Search of human proteins with 19923959

Search of human proteins with 19923959

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923959 serine dehydratase-like [Homo sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923959 serine dehydratase-like [Homo sapiens]                    657   0.0  
gi|33469958 serine dehydratase [Homo sapiens]                         390   e-108
gi|11345492 serine racemase [Homo sapiens]                             94   2e-19
gi|4557415 cystathionine-beta-synthase [Homo sapiens]                  39   0.005
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             32   1.0  
gi|71725371 solute carrier family 10 (sodium/bile acid cotranspo...    31   1.7  
gi|14149785 solute carrier family 10 (sodium/bile acid cotranspo...    30   3.0  
gi|189571643 sulfatase 1 [Homo sapiens]                                29   6.6  
gi|189571641 sulfatase 1 [Homo sapiens]                                29   6.6  
gi|189571638 sulfatase 1 [Homo sapiens]                                29   6.6  
gi|189571636 sulfatase 1 [Homo sapiens]                                29   6.6  
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]           29   6.6  
gi|27734925 hypothetical protein LOC285315 [Homo sapiens]              28   8.6  

>gi|19923959 serine dehydratase-like [Homo sapiens]
          Length = 329

 Score =  657 bits (1695), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMA 60
           MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMA
Sbjct: 1   MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMA 60

Query: 61  KKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVW 120
           KKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVW
Sbjct: 61  KKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVW 120

Query: 121 DEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLA 180
           DEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLA
Sbjct: 121 DEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLA 180

Query: 181 GVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALE 240
           GVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALE
Sbjct: 181 GVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALE 240

Query: 241 CMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPS 300
           CMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPS
Sbjct: 241 CMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPS 300

Query: 301 LTSVVVIVCGGNNINSRELQALKTHLGQV 329
           LTSVVVIVCGGNNINSRELQALKTHLGQV
Sbjct: 301 LTSVVVIVCGGNNINSRELQALKTHLGQV 329


>gi|33469958 serine dehydratase [Homo sapiens]
          Length = 328

 Score =  390 bits (1001), Expect = e-108
 Identities = 196/317 (61%), Positives = 249/317 (78%), Gaps = 1/317 (0%)

Query: 12  EPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSS 71
           EP HV TP+ +S ALS++AG  V+LK ++ QPSGSFKIRGIGHFC+  AK+GC H VCSS
Sbjct: 5   EPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSS 64

Query: 72  GGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELA 131
            GNAG+AAAYAAR+LG+PATIV+P +T    ++RL+ EGA V++ G++ DEA   A+ LA
Sbjct: 65  AGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALA 124

Query: 132 KRD-GWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVG 190
           K + GW  +PPFD PLIW+GHAS+V+ELK  L   PGA+ L+VGGGGLL GVV GL EVG
Sbjct: 125 KNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVG 184

Query: 191 WQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSE 250
           W  VP+IAMET GAH F+AA TAGKLV+LP ITSVAK+LG KTV A+AL+  Q   I SE
Sbjct: 185 WGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 244

Query: 251 VVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCG 310
           V+ D EAV+A+++ +DDE++LVEPACGAALAA+YS ++++LQ EG L   L S+VVIVCG
Sbjct: 245 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 304

Query: 311 GNNINSRELQALKTHLG 327
           G+NI+  +L+ALK  LG
Sbjct: 305 GSNISLAQLRALKEQLG 321


>gi|11345492 serine racemase [Homo sapiens]
          Length = 340

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 88/308 (28%), Positives = 146/308 (47%), Gaps = 28/308 (9%)

Query: 17  VTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRG----IGHFCQEMAKKGCRHLVCSSG 72
           +TP+L S  L+Q+ G  +F KCE  Q +GSFKIRG    +     +  ++  + +V  S 
Sbjct: 25  LTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSS 84

Query: 73  GNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQE-LA 131
           GN G A  YAA+  GIPA IV+P++        +Q  GA +     V+ E +  ++E +A
Sbjct: 85  GNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-----VYCEPSDESRENVA 139

Query: 132 KRDGWEN----VPPFDHPLIWKGHASLVQELKAVLRTPP--GALVLAVGGGGLLAGVVAG 185
           KR   E     V P   P +  G  ++  E   VL   P   ALV+ VGGGG+LAG +A 
Sbjct: 140 KRVTEETEGIMVHPNQEPAVIAGQGTIALE---VLNQVPLVDALVVPVGGGGMLAG-IAI 195

Query: 186 LLEVGWQHVPIIAMETHGA-HCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQV 244
            ++     V + A E   A  C+ + +    +  L    ++A  +   ++       ++ 
Sbjct: 196 TVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV-KSSIGLNTWPIIRD 254

Query: 245 CKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSV 304
                  V + E   A Q + +  ++L+EP  G  +AA+ S      Q    + P + ++
Sbjct: 255 LVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLS------QHFQTVSPEVKNI 308

Query: 305 VVIVCGGN 312
            +++ GGN
Sbjct: 309 CIVLSGGN 316


>gi|4557415 cystathionine-beta-synthase [Homo sapiens]
          Length = 551

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 19/187 (10%)

Query: 18  TPLLESWALSQVAGMPVFL--KCENVQPSGSFKIRGIGHFCQEMAKKGCRH----LVCSS 71
           TP++    + +  G+   L  KCE     GS K R      ++  + G       ++  +
Sbjct: 87  TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 146

Query: 72  GGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELA 131
            GN GI  A AA   G    IV+PE  S + V  L+  GAE+  T      A   + E  
Sbjct: 147 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTP---TNARFDSPESH 203

Query: 132 KRDGW--ENVPPFDHPLIWKGHAS--------LVQELKAVLRTPPGALVLAVGGGGLLAG 181
               W  +N  P  H L    +AS           E+          LV +VG GG + G
Sbjct: 204 VGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITG 263

Query: 182 VVAGLLE 188
           +   L E
Sbjct: 264 IARKLKE 270


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 89  PATIVLPESTSL----QVVQRLQGEGAEVQLTGKVWDEANLRAQELAKRD---GWENVPP 141
           P  +  PE  ++    Q+++ L G G+E+Q   +  D+   R  ++ K     GWE V P
Sbjct: 320 PVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVP 379

Query: 142 FDHPL 146
            +  L
Sbjct: 380 LEEGL 384


>gi|71725371 solute carrier family 10 (sodium/bile acid
           cotransporter family), member 7 isoform b [Homo sapiens]
          Length = 340

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 279 ALAAIYSGLLRRLQAEGCLPPSLTSVVVI--VCGGNNINSRELQALKTHLGQV 329
           ++  I   LL+ LQ  GC+PP ++S V++    GGN   +    A  + LG V
Sbjct: 96  SITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIV 148


>gi|14149785 solute carrier family 10 (sodium/bile acid
           cotransporter family), member 7 isoform c [Homo sapiens]
          Length = 159

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 279 ALAAIYSGLLRRLQAEGCLPPSLTSVVVI--VCGGN 312
           ++  I   LL+ LQ  GC+PP ++S V++    GGN
Sbjct: 96  SITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGN 131


>gi|189571643 sulfatase 1 [Homo sapiens]
          Length = 871

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 7/52 (13%)

Query: 41  VQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATI 92
           +QP    K    GH       KG R L  SSGGN G   A ++  +G P T+
Sbjct: 568 LQPRNIAKRHDEGH-------KGPRDLQASSGGNRGRMLADSSNAVGPPTTV 612


>gi|189571641 sulfatase 1 [Homo sapiens]
          Length = 871

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 7/52 (13%)

Query: 41  VQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATI 92
           +QP    K    GH       KG R L  SSGGN G   A ++  +G P T+
Sbjct: 568 LQPRNIAKRHDEGH-------KGPRDLQASSGGNRGRMLADSSNAVGPPTTV 612


>gi|189571638 sulfatase 1 [Homo sapiens]
          Length = 871

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 7/52 (13%)

Query: 41  VQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATI 92
           +QP    K    GH       KG R L  SSGGN G   A ++  +G P T+
Sbjct: 568 LQPRNIAKRHDEGH-------KGPRDLQASSGGNRGRMLADSSNAVGPPTTV 612


>gi|189571636 sulfatase 1 [Homo sapiens]
          Length = 871

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 7/52 (13%)

Query: 41  VQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATI 92
           +QP    K    GH       KG R L  SSGGN G   A ++  +G P T+
Sbjct: 568 LQPRNIAKRHDEGH-------KGPRDLQASSGGNRGRMLADSSNAVGPPTTV 612


>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
          Length = 640

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 12/35 (34%), Positives = 21/35 (60%)

Query: 167 GALVLAVGGGGLLAGVVAGLLEVGWQHVPIIAMET 201
           G  VL VG GG+   ++  L+  G+ H+ +I ++T
Sbjct: 17  GGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDT 51


>gi|27734925 hypothetical protein LOC285315 [Homo sapiens]
          Length = 251

 Score = 28.5 bits (62), Expect = 8.6
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 6/89 (6%)

Query: 92  IVLPESTSLQVVQR----LQGEGAEVQLTGKVWDEANLRAQELA--KRDGWENVPPFDHP 145
           I LP   SL+   R    ++  G E+  TGK W +  L+  +L   +  G EN   F + 
Sbjct: 55  ITLPIIASLRKEPRGALLVKLAGVELAETGKAWLQKELKPSQLLWFQLLGKENSALFCYL 114

Query: 146 LIWKGHASLVQELKAVLRTPPGALVLAVG 174
           L+ KG    V   + +LR   G  VL  G
Sbjct: 115 LVSKGGYFSVNLNEEILRRGLGKTVLVKG 143


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,630,317
Number of Sequences: 37866
Number of extensions: 532689
Number of successful extensions: 1257
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1244
Number of HSP's gapped (non-prelim): 13
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.