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Search of human proteins with 197333868
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197333868 T-box 2 [Homo sapiens]
(712 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197333868 T-box 2 [Homo sapiens] 1430 0.0
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 687 0.0
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 675 0.0
gi|18129690 T-box 4 [Homo sapiens] 266 4e-71
gi|5174711 T-box 1 isoform B [Homo sapiens] 249 8e-66
gi|18104952 T-box 1 isoform C [Homo sapiens] 249 8e-66
gi|18104950 T-box 1 isoform A [Homo sapiens] 249 8e-66
gi|18201900 T-box 6 [Homo sapiens] 249 8e-66
gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 248 2e-65
gi|18201896 T-box 5 isoform 2 [Homo sapiens] 247 3e-65
gi|18201894 T-box 5 isoform 3 [Homo sapiens] 247 3e-65
gi|18201892 T-box 5 isoform 1 [Homo sapiens] 247 3e-65
gi|31652232 T-box 5 isoform 1 [Homo sapiens] 247 3e-65
gi|32567784 T-box 10 [Homo sapiens] 232 1e-60
gi|122937456 T-box 18 [Homo sapiens] 230 3e-60
gi|55770860 T-box 15 [Homo sapiens] 216 8e-56
gi|122937388 MAX gene associated [Homo sapiens] 210 3e-54
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 209 5e-54
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 209 5e-54
gi|4507339 transcription factor T [Homo sapiens] 199 1e-50
gi|22538470 eomesodermin [Homo sapiens] 194 2e-49
gi|7019549 T-box 21 [Homo sapiens] 189 6e-48
gi|5730081 T-box, brain, 1 [Homo sapiens] 185 1e-46
gi|4827024 T-box 19 [Homo sapiens] 179 1e-44
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 169 6e-42
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 54 7e-07
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 54 7e-07
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 54 7e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens] 53 1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 53 1e-06
>gi|197333868 T-box 2 [Homo sapiens]
Length = 712
Score = 1430 bits (3701), Expect = 0.0
Identities = 712/712 (100%), Positives = 712/712 (100%)
Query: 1 MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGA 60
MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGA
Sbjct: 1 MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGA 60
Query: 61 AAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHK 120
AAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHK
Sbjct: 61 AAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHK 120
Query: 121 LGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADP 180
LGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADP
Sbjct: 121 LGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADP 180
Query: 181 EMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRAN 240
EMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRAN
Sbjct: 181 EMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRAN 240
Query: 241 DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLT 300
DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLT
Sbjct: 241 DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLT 300
Query: 301 LPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADS 360
LPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADS
Sbjct: 301 LPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADS 360
Query: 361 DPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLR 420
DPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLR
Sbjct: 361 DPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLR 420
Query: 421 SLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFF 480
SLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFF
Sbjct: 421 SLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFF 480
Query: 481 GPLGAGQPLFLHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPA 540
GPLGAGQPLFLHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPA
Sbjct: 481 GPLGAGQPLFLHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPA 540
Query: 541 ASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAA 600
ASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAA
Sbjct: 541 ASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAA 600
Query: 601 AAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPLP 660
AAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPLP
Sbjct: 601 AAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPLP 660
Query: 661 ELALRKVGAPSRGALSPSGSAKEAANELQSIQRLVSGLESQRALSPGRESPK 712
ELALRKVGAPSRGALSPSGSAKEAANELQSIQRLVSGLESQRALSPGRESPK
Sbjct: 661 ELALRKVGAPSRGALSPSGSAKEAANELQSIQRLVSGLESQRALSPGRESPK 712
>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
Length = 723
Score = 687 bits (1772), Expect = 0.0
Identities = 425/761 (55%), Positives = 488/761 (64%), Gaps = 97/761 (12%)
Query: 1 MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPP---------GALAKP 51
MR+P + ++MAYHPF R DF MSA L QP FFPAL LPP GALAKP
Sbjct: 5 MRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGH-QPPFFPALTLPPNGAAALSLPGALAKP 63
Query: 52 LPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEA 111
+ D AAE G+ S+LGP AHLR LK++EPE+EVEDDPKV LEA
Sbjct: 64 IMDQ-----------LVGAAETGIPFSSLGPQ---AHLRPLKTMEPEEEVEDDPKVHLEA 109
Query: 112 KELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSR 171
KELWDQFHK GTEMVITKSGRRMFPPFKVR SGLDKKAKYILLMDI+AADDCRYKFHNSR
Sbjct: 110 KELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSR 169
Query: 172 WMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQ 231
WMVAGKADPEMPKRMYIHPDSPATGEQWM+K V FHKLKLTNNISDKHGFTILNSMHKYQ
Sbjct: 170 WMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQ 229
Query: 232 PRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNG 291
PRFHIVRANDILKLPYSTFRTY+FPET+FIAVTAYQNDKITQLKIDNNPFAKGFRDTGNG
Sbjct: 230 PRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNG 289
Query: 292 RREKRKQLTLPSLRLYEEHCKPER---DGAESDASSCDPPPAREPPTSPGAAPSPLRLHR 348
RREKRKQLTL S+R+++E K E D + S+ ++ + P + S L+
Sbjct: 290 RREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLC 349
Query: 349 ARAEEKSCAADSDPE--PERLSEERAGAPLGRSPAPDSASP---TRLTEPERAR-----E 398
E A+S E PE + P D SP L ER R +
Sbjct: 350 PSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLD 409
Query: 399 RRSPERGKEPA----ESGGDGPFGLRSLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQT 454
+ SP+ PA + G G RS +E + +E R A GKE APL VQT
Sbjct: 410 KASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEAR--ALPGKE-AFAPLTVQT 466
Query: 455 DSASP-LGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFTMGPGAFSAM---GMGH 510
D+A+ L G LPGL F+ L GQQFF G PLFLHP QF MG GAFS+M GMG
Sbjct: 467 DAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHPSQFAMG-GAFSSMAAAGMGP 521
Query: 511 LLASVAGGGNGGGGGPGTAAGLDAGGLGPAASA----ASTAAPFPFHLSQHMLASQGIPM 566
LLA+V+G G +GLD+ + AA+A ++AA PFHL QH+LASQG+ M
Sbjct: 522 LLATVSGASTG-------VSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAM 574
Query: 567 PTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPF--LGSARPRLRFSPY 624
FG LFPYPYTYMAAAAAA+S AAA+ S+ R PF L + RPRLR+SPY
Sbjct: 575 SPFGSLFPYPYTYMAAAAAASS-----------AAASSSVHRHPFLNLNTMRPRLRYSPY 623
Query: 625 QIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPL------------PELALRKVGAPSR 672
IPV +P +SLLTT L S + AAG + + L EL R S
Sbjct: 624 SIPVPVPDGSSLLTTALPSMAA-AAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSS 682
Query: 673 G-ALSPSGSA-KEAA-NELQSIQRLVSGLESQ----RALSP 706
+LSP A KEAA +ELQSIQRLVSGLE++ R+ SP
Sbjct: 683 SMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRSASP 723
>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
Length = 743
Score = 675 bits (1741), Expect = 0.0
Identities = 425/781 (54%), Positives = 488/781 (62%), Gaps = 117/781 (14%)
Query: 1 MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPP---------GALAKP 51
MR+P + ++MAYHPF R DF MSA L QP FFPAL LPP GALAKP
Sbjct: 5 MRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGH-QPPFFPALTLPPNGAAALSLPGALAKP 63
Query: 52 LPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEA 111
+ D AAE G+ S+LGP AHLR LK++EPE+EVEDDPKV LEA
Sbjct: 64 IMDQ-----------LVGAAETGIPFSSLGPQ---AHLRPLKTMEPEEEVEDDPKVHLEA 109
Query: 112 KELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSR 171
KELWDQFHK GTEMVITKSGRRMFPPFKVR SGLDKKAKYILLMDI+AADDCRYKFHNSR
Sbjct: 110 KELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSR 169
Query: 172 WMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF---------- 221
WMVAGKADPEMPKRMYIHPDSPATGEQWM+K V FHKLKLTNNISDKHGF
Sbjct: 170 WMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHAT 229
Query: 222 ----------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKI 271
TILNSMHKYQPRFHIVRANDILKLPYSTFRTY+FPET+FIAVTAYQNDKI
Sbjct: 230 WQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKI 289
Query: 272 TQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPER---DGAESDASSCDPP 328
TQLKIDNNPFAKGFRDTGNGRREKRKQLTL S+R+++E K E D + S+ ++ +
Sbjct: 290 TQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCF 349
Query: 329 PAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPE--PERLSEERAGAPLGRSPAPDSAS 386
P + S L+ E A+S E PE + P D S
Sbjct: 350 AQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGS 409
Query: 387 P---TRLTEPERAR-----ERRSPERGKEPA----ESGGDGPFGLRSLEKERAEARRKDE 434
P L ER R ++ SP+ PA + G G RS +E + +E
Sbjct: 410 PAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEE 469
Query: 435 GRKEAAEGKEQGLAPLVVQTDSASP-LGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHP 493
R A GKE APL VQTD+A+ L G LPGL F+ L GQQFF G PLFLHP
Sbjct: 470 AR--ALPGKE-AFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHP 522
Query: 494 GQFTMGPGAFSAM---GMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASA----AST 546
QF MG GAFS+M GMG LLA+V+G G +GLD+ + AA+A ++
Sbjct: 523 SQFAMG-GAFSSMAAAGMGPLLATVSGASTG-------VSGLDSTAMASAAAAQGLSGAS 574
Query: 547 AAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSL 606
AA PFHL QH+LASQG+ M FG LFPYPYTYMAAAAAA+S AAA+ S+
Sbjct: 575 AATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASS-----------AAASSSV 623
Query: 607 SRSPF--LGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPL----- 659
R PF L + RPRLR+SPY IPV +P +SLLTT L S + AAG + + L
Sbjct: 624 HRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAA-AAGPLDGKVAALAASPA 682
Query: 660 -------PELALRKVGAPSRG-ALSPSGSA-KEAA-NELQSIQRLVSGLESQ----RALS 705
EL R S +LSP A KEAA +ELQSIQRLVSGLE++ R+ S
Sbjct: 683 SVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRSAS 742
Query: 706 P 706
P
Sbjct: 743 P 743
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 266 bits (681), Expect = 4e-71
Identities = 139/237 (58%), Positives = 172/237 (72%), Gaps = 6/237 (2%)
Query: 53 PDPGLAGAAAAAAAAAAAAEAGLHVSALGPHP-PAAHLRSLKSLEPEDEVEDDPKVTLEA 111
P P L A+AA A A A GL +ALG P P A + + + E + ++ KV L
Sbjct: 17 PGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAAE---QTIENIKVGLHE 73
Query: 112 KELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSR 171
KELW +FH+ GTEM+ITK+GRRMFP +KV+V+G++ K KYILL+DIV ADD RYKF +++
Sbjct: 74 KELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNK 133
Query: 172 WMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQ 231
WMVAGKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILNSMHKYQ
Sbjct: 134 WMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 193
Query: 232 PRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFR 286
PR HIV+A N+ + F T+VFPET FI+VT+YQN KITQLKI+NNPFAKGFR
Sbjct: 194 PRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFR 250
>gi|5174711 T-box 1 isoform B [Homo sapiens]
Length = 372
Score = 249 bits (635), Expect = 8e-66
Identities = 134/258 (51%), Positives = 168/258 (65%), Gaps = 13/258 (5%)
Query: 35 PSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKS 94
P + P A PGA P P A AA AA +AAAE P A+ + K+
Sbjct: 48 PRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEP--------EGPGASCAAAAKA 99
Query: 95 LEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILL 154
++ V LE K LWD+F++LGTEM++TK+GRRMFP F+V++ G+D A Y+LL
Sbjct: 100 PVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLL 159
Query: 155 MDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLT 212
MD V DD RY+ FH+S W+VAGKADP P R++ HPDSPA G QWM + V+F KLKLT
Sbjct: 160 MDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLT 219
Query: 213 NNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTAYQND 269
NN+ D +G ILNSMH+YQPRFH+V + D K F+T+VF ET F AVTAYQN
Sbjct: 220 NNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNH 279
Query: 270 KITQLKIDNNPFAKGFRD 287
+ITQLKI +NPFAKGFRD
Sbjct: 280 RITQLKIASNPFAKGFRD 297
Score = 30.0 bits (66), Expect = 7.8
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)
Query: 491 LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPF 550
+H T AF+A + L A+ GG PG AA A GP P
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAA--------GGFPG-AASPGADPYGPREPP-----PP 46
Query: 551 PFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS 609
P A+ G P P YP+ A AA +A+A P A+ AAAA + ++
Sbjct: 47 PPRYDPCAAAAPGAPGPP-PPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN 104
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 249 bits (635), Expect = 8e-66
Identities = 134/258 (51%), Positives = 168/258 (65%), Gaps = 13/258 (5%)
Query: 35 PSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKS 94
P + P A PGA P P A AA AA +AAAE P A+ + K+
Sbjct: 48 PRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEP--------EGPGASCAAAAKA 99
Query: 95 LEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILL 154
++ V LE K LWD+F++LGTEM++TK+GRRMFP F+V++ G+D A Y+LL
Sbjct: 100 PVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLL 159
Query: 155 MDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLT 212
MD V DD RY+ FH+S W+VAGKADP P R++ HPDSPA G QWM + V+F KLKLT
Sbjct: 160 MDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLT 219
Query: 213 NNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTAYQND 269
NN+ D +G ILNSMH+YQPRFH+V + D K F+T+VF ET F AVTAYQN
Sbjct: 220 NNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNH 279
Query: 270 KITQLKIDNNPFAKGFRD 287
+ITQLKI +NPFAKGFRD
Sbjct: 280 RITQLKIASNPFAKGFRD 297
Score = 34.7 bits (78), Expect = 0.32
Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 34/100 (34%)
Query: 7 AASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAG------- 59
A+ + +HP+ P AAA + A + P P P PGL G
Sbjct: 407 ASEPLHHHPYKYP-----------AAAYDHYLGAKSRPA-----PYPLPGLRGHGYHPHA 450
Query: 60 -----------AAAAAAAAAAAAEAGLHVSALGPHPPAAH 88
AAAAAAAAAAAA A S+ G PP ++
Sbjct: 451 HPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPPGSY 490
Score = 33.5 bits (75), Expect = 0.70
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query: 481 GPLGAGQPLFLHPGQF---TMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGL 537
GP G P HP Q + P A G G L+ + G G P L+A
Sbjct: 351 GPAVLGDPA--HPPQLLARVLSPSLPGAGGAGGLVP-LPGAPGGRPSPPNPELRLEA--- 404
Query: 538 GPAASAASTAAPFPFHLS--QHMLASQG----IPMPTFGGLFPYPYTYMAAAAAAASALP 591
P AS P+ + + H L ++ P+P G +P+ + S P
Sbjct: 405 -PGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVS--P 461
Query: 592 ATSAAAAAAAAAGSLSRSPFLGSARP 617
A +AAAAAAAAA + + G+A P
Sbjct: 462 AAAAAAAAAAAAAAANMYSSAGAAPP 487
Score = 30.0 bits (66), Expect = 7.8
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)
Query: 491 LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPF 550
+H T AF+A + L A+ GG PG AA A GP P
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAA--------GGFPG-AASPGADPYGPREPP-----PP 46
Query: 551 PFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS 609
P A+ G P P YP+ A AA +A+A P A+ AAAA + ++
Sbjct: 47 PPRYDPCAAAAPGAPGPP-PPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN 104
>gi|18104950 T-box 1 isoform A [Homo sapiens]
Length = 398
Score = 249 bits (635), Expect = 8e-66
Identities = 134/258 (51%), Positives = 168/258 (65%), Gaps = 13/258 (5%)
Query: 35 PSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKS 94
P + P A PGA P P A AA AA +AAAE P A+ + K+
Sbjct: 48 PRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEP--------EGPGASCAAAAKA 99
Query: 95 LEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILL 154
++ V LE K LWD+F++LGTEM++TK+GRRMFP F+V++ G+D A Y+LL
Sbjct: 100 PVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLL 159
Query: 155 MDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLT 212
MD V DD RY+ FH+S W+VAGKADP P R++ HPDSPA G QWM + V+F KLKLT
Sbjct: 160 MDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLT 219
Query: 213 NNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTAYQND 269
NN+ D +G ILNSMH+YQPRFH+V + D K F+T+VF ET F AVTAYQN
Sbjct: 220 NNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNH 279
Query: 270 KITQLKIDNNPFAKGFRD 287
+ITQLKI +NPFAKGFRD
Sbjct: 280 RITQLKIASNPFAKGFRD 297
Score = 30.0 bits (66), Expect = 7.8
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)
Query: 491 LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPF 550
+H T AF+A + L A+ GG PG AA A GP P
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAA--------GGFPG-AASPGADPYGPREPP-----PP 46
Query: 551 PFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS 609
P A+ G P P YP+ A AA +A+A P A+ AAAA + ++
Sbjct: 47 PPRYDPCAAAAPGAPGPP-PPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN 104
>gi|18201900 T-box 6 [Homo sapiens]
Length = 436
Score = 249 bits (635), Expect = 8e-66
Identities = 143/346 (41%), Positives = 190/346 (54%), Gaps = 21/346 (6%)
Query: 13 YHP--FHAPRPADFPMSAFLAAAQPSFFPALA--LPPGALAKPLPDPGLAGAAAAAAAAA 68
YHP + A + + A SF PALA L P D L+G AA A
Sbjct: 2 YHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTLA 61
Query: 69 AAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVIT 128
A L A+G P + +L SL ++LE +ELW +F +GTEM+IT
Sbjct: 62 AHPPLPLLPPAMGTEPAPSAPEALHSLP-------GVSLSLENRELWKEFSSVGTEMIIT 114
Query: 129 KSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYI 188
K+GRRMFP +V V+GLD +A+Y+ L+D++ D RY++ RW +GKA+P +P R+YI
Sbjct: 115 KAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYI 174
Query: 189 HPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYS 248
HPDSPATG WM +PV+FH++KLTN+ D HG IL+SMHKYQPR H+VRA + +
Sbjct: 175 HPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWG 234
Query: 249 TFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYE 308
++ FPET FI+VTAYQN +ITQLKI NPFAKGFR+ G + +R LR E
Sbjct: 235 GMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPE 294
Query: 309 EHCKPERDGAESDASSCD----------PPPAREPPTSPGAAPSPL 344
++ CD P P AAP+PL
Sbjct: 295 PAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPL 340
>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
Length = 447
Score = 248 bits (632), Expect = 2e-65
Identities = 119/187 (63%), Positives = 147/187 (78%), Gaps = 6/187 (3%)
Query: 108 TLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKF 167
+LE KELWD+FH+LGTEM+ITKSGRRMFP +V SG+D +AKYI+LMDIV D+ RY++
Sbjct: 103 SLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRY 162
Query: 168 --HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
H S W+VAGKADP +P R+Y+HPDSP TGEQ + + V+F K+KLTNN D+HG ILN
Sbjct: 163 AYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILN 222
Query: 226 SMHKYQPRFHIVRAND----ILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPF 281
SMHKYQPR HI++ D +L L FRT++FPET F AVTAYQN IT+LKID+NPF
Sbjct: 223 SMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPF 282
Query: 282 AKGFRDT 288
AKGFRD+
Sbjct: 283 AKGFRDS 289
>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
Length = 349
Score = 247 bits (630), Expect = 3e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
Query: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
Query: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
Query: 284 GFR 286
GFR
Sbjct: 235 GFR 237
>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
Length = 468
Score = 247 bits (630), Expect = 3e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
Query: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 65 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 124
Query: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 125 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 184
Query: 284 GFR 286
GFR
Sbjct: 185 GFR 187
>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 247 bits (630), Expect = 3e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
Query: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
Query: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
Query: 284 GFR 286
GFR
Sbjct: 235 GFR 237
>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 247 bits (630), Expect = 3e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
Query: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
Query: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
Query: 284 GFR 286
GFR
Sbjct: 235 GFR 237
>gi|32567784 T-box 10 [Homo sapiens]
Length = 385
Score = 232 bits (591), Expect = 1e-60
Identities = 112/203 (55%), Positives = 149/203 (73%), Gaps = 10/203 (4%)
Query: 96 EPEDEVEDDPKVT-----LEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAK 150
EP + +P+V+ LE K LW++F++LGTEM++TK+GRRMFPPF+V++ G+D A
Sbjct: 51 EPTGQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLAD 110
Query: 151 YILLMDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHK 208
Y LLMD + DD RY+ FH+S W+VAGKADP P R++ HPDSPA G QWM + V+F K
Sbjct: 111 YALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDK 170
Query: 209 LKLTNNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTA 265
LKLTNN+ D +G ILNSMH+YQPRFH+V + D + F++++F ET F AVTA
Sbjct: 171 LKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQENFKSFIFTETQFTAVTA 230
Query: 266 YQNDKITQLKIDNNPFAKGFRDT 288
YQN +ITQLKI +NPFAKGFR++
Sbjct: 231 YQNHRITQLKIASNPFAKGFRES 253
>gi|122937456 T-box 18 [Homo sapiens]
Length = 607
Score = 230 bits (587), Expect = 3e-60
Identities = 122/262 (46%), Positives = 161/262 (61%), Gaps = 9/262 (3%)
Query: 40 ALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPED 99
AL P GA + P AA + +++ G P + RSL
Sbjct: 74 ALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTPL 133
Query: 100 EVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVA 159
P+V L+ ELW +FH++GTEM+ITK+GRRMFP +V++SGLD +Y + MDIV
Sbjct: 134 PSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVP 193
Query: 160 ADDCRYKF--HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISD 217
D+ RY++ H+S+WMVAG AD +P R+YIHPDSPA+GE WM + ++F KLKLTNN D
Sbjct: 194 VDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELD 253
Query: 218 KHGFTILNSMHKYQPRFHIVR------ANDILKLPYST-FRTYVFPETDFIAVTAYQNDK 270
G IL+SMHKYQPR H++R + I +P + + FPET F VTAYQN +
Sbjct: 254 DQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQ 313
Query: 271 ITQLKIDNNPFAKGFRDTGNGR 292
IT+LKID NPFAKGFRD+G R
Sbjct: 314 ITRLKIDRNPFAKGFRDSGRNR 335
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 216 bits (549), Expect = 8e-56
Identities = 105/199 (52%), Positives = 141/199 (70%), Gaps = 9/199 (4%)
Query: 103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADD 162
++ +V L+ +LW +FH +GTEM+ITK+GRRMFP +V+++GLD +Y + MDIV D+
Sbjct: 5 EEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDN 64
Query: 163 CRYKF--HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHG 220
RY++ H+S+WMVAG AD +P R+YIHPDS A+G+ WM + V+F KLKLTNN D G
Sbjct: 65 KRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQG 124
Query: 221 FTILNSMHKYQPRFHIVRANDILKLPYST-------FRTYVFPETDFIAVTAYQNDKITQ 273
IL+SMHKYQPR H++R + L + +T+ FPET F VTAYQN +IT+
Sbjct: 125 HIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITR 184
Query: 274 LKIDNNPFAKGFRDTGNGR 292
LKID NPFAKGFRD+G R
Sbjct: 185 LKIDRNPFAKGFRDSGRNR 203
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 210 bits (535), Expect = 3e-54
Identities = 119/297 (40%), Positives = 167/297 (56%), Gaps = 39/297 (13%)
Query: 30 LAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHL 89
+A A P+FF L P D G+ A A A++ + +
Sbjct: 17 VAGAAPTFFVILKQPGNGKT----DQGILVTNQDACALASSVSSPVKSKG---------- 62
Query: 90 RSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKA 149
K P D VTL+ +W++F+ TEM++TK GRRMFP + ++GLD
Sbjct: 63 ---KICLPADCTVGGITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNL 119
Query: 150 KYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKL 209
KYIL+MDI D+ RYK++ W +GKA+P + R++IHP+SP+TG WM +PV+F+KL
Sbjct: 120 KYILVMDISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKL 179
Query: 210 KLTNNISDKHGFTILNSMHKYQPRFHIV---RANDILKLPYSTFRTYVFPETDFIAVTAY 266
KLTNN D+ G IL+SMH+Y PR H+V +A ++++L T+ FP+T+F AVTAY
Sbjct: 180 KLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAVEVIQLNGPGVHTFTFPQTEFFAVTAY 239
Query: 267 QNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPERDGAESDAS 323
QN +ITQLKID NPFAKGFRD G KP+RDG + ++S
Sbjct: 240 QNIQITQLKIDYNPFAKGFRDDGLNN-------------------KPQRDGKQKNSS 277
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 209 bits (533), Expect = 5e-54
Identities = 116/253 (45%), Positives = 155/253 (61%), Gaps = 16/253 (6%)
Query: 102 EDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAAD 161
E D ++ L+ ELW +FH +GTEM+ITK+GRRMFP +V+V GLD +Y + +D+V D
Sbjct: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
Query: 162 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDK 218
RY+ +H+S+WMVAG D + R Y+HPDSP +GE WM + ++F ++KLTNN D
Sbjct: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
Query: 219 HGFTILNSMHKYQPRFHIVR------ANDILKLPYSTFRTYVFPETDFIAVTAYQNDKIT 272
G IL SMHKY+PR H++ + I LP +T+ F ET+F VTAYQN +IT
Sbjct: 209 KGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQIT 268
Query: 273 QLKIDNNPFAKGFRDTGNGRREKRKQL-TLPSLRLYEEHCKPERDGAESDASSCDPPPAR 331
+LKI+ NPFAKGFRDTG R L T P + K GA++ + S
Sbjct: 269 KLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFK--TFGADTQSGS----SGS 322
Query: 332 EPPTSPGAAPSPL 344
P TS G APSPL
Sbjct: 323 SPVTSSGGAPSPL 335
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 209 bits (533), Expect = 5e-54
Identities = 116/253 (45%), Positives = 155/253 (61%), Gaps = 16/253 (6%)
Query: 102 EDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAAD 161
E D ++ L+ ELW +FH +GTEM+ITK+GRRMFP +V+V GLD +Y + +D+V D
Sbjct: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
Query: 162 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDK 218
RY+ +H+S+WMVAG D + R Y+HPDSP +GE WM + ++F ++KLTNN D
Sbjct: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
Query: 219 HGFTILNSMHKYQPRFHIVR------ANDILKLPYSTFRTYVFPETDFIAVTAYQNDKIT 272
G IL SMHKY+PR H++ + I LP +T+ F ET+F VTAYQN +IT
Sbjct: 209 KGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQIT 268
Query: 273 QLKIDNNPFAKGFRDTGNGRREKRKQL-TLPSLRLYEEHCKPERDGAESDASSCDPPPAR 331
+LKI+ NPFAKGFRDTG R L T P + K GA++ + S
Sbjct: 269 KLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFK--TFGADTQSGS----SGS 322
Query: 332 EPPTSPGAAPSPL 344
P TS G APSPL
Sbjct: 323 SPVTSSGGAPSPL 335
>gi|4507339 transcription factor T [Homo sapiens]
Length = 435
Score = 199 bits (505), Expect = 1e-50
Identities = 101/192 (52%), Positives = 127/192 (66%), Gaps = 5/192 (2%)
Query: 96 EPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLM 155
E D E + +V LE ELW +F +L EM++TK+GRRMFP KV VSGLD A Y L+
Sbjct: 33 EKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLL 92
Query: 156 DIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNI 215
D VAAD+ R+K+ N W+ GK +P+ P +YIHPDSP G WM PV+F K+KLTN +
Sbjct: 93 DFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKL 152
Query: 216 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLK 275
+ G +LNS+HKY+PR HIVR P ++ FPET FIAVTAYQN++IT LK
Sbjct: 153 NG-GGQIMLNSLHKYEPRIHIVRVGG----PQRMITSHCFPETQFIAVTAYQNEEITALK 207
Query: 276 IDNNPFAKGFRD 287
I NPFAK F D
Sbjct: 208 IKYNPFAKAFLD 219
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 194 bits (493), Expect = 2e-49
Identities = 136/373 (36%), Positives = 185/373 (49%), Gaps = 47/373 (12%)
Query: 4 PALAASAMAYHPFH-APRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAA 62
P AA+ + P + AP A +P + L P FPA PPG + PG +
Sbjct: 164 PYQAAAGAPHGPVYPAPNGARYPYGSMLP---PGGFPAAVCPPG---RAQFGPGAGAGSG 217
Query: 63 AAAAAAAAAEAGLH-----VSALGPHPPAAHLRSLKSLEPEDEVEDDPK--VTLEAKELW 115
A ++ G + GP+P AA S L + V L + LW
Sbjct: 218 AGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLW 277
Query: 116 DQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVA 175
+FH+ TEM+ITK GRRMFP ++GL+ A Y + +++V AD ++F +W+
Sbjct: 278 LKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTC 337
Query: 176 GKADPEMP-KRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFT---ILNSMHKYQ 231
GKAD M +MY+HP+SP TG WM + ++F KLKLTNN + T +L S+HKYQ
Sbjct: 338 GKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQ 397
Query: 232 PRFHIVRAN----DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRD 287
PR HIV + L P T +T+ F ET FIAVTAYQN ITQLKID+NPFAKGFRD
Sbjct: 398 PRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456
Query: 288 TGNGRRE--------------KRKQLTLPSLRLYE-EHCKPERDGAESDASS---CDPP- 328
+ + + TLP R Y E P+ +G S S +PP
Sbjct: 457 NYDSSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQ 516
Query: 329 -----PAREPPTS 336
P ++P T+
Sbjct: 517 RWLVTPVQQPGTN 529
Score = 52.8 bits (125), Expect = 1e-06
Identities = 67/229 (29%), Positives = 84/229 (36%), Gaps = 33/229 (14%)
Query: 337 PGAAPSPLRLHRARAEEK-----SCAADSDPEPERLSEERAGAPLGRSPAPDS-ASPTRL 390
P AAPSP +L +A +K SC A S EP S A L + A D+ AS +
Sbjct: 37 PSAAPSPQKLDLDKASKKFSGSLSCEAVSG-EPAAASAGAPAAMLSDTDAGDAFASAAAV 95
Query: 391 TEPERARERRSPERGKEPAESGGDGPFGLRSLEKERAEARRKDEGRKEAAEGKEQGLAPL 450
+P P + P G L A A A L+
Sbjct: 96 AKPG-------------PPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSE 142
Query: 451 VVQTDSASPLGA------GHLPGLAFSSHLHGQQFFGPLGAGQPL--FLHPGQFTMG--P 500
S P G+ P A + HG + P GA P L PG F P
Sbjct: 143 RYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCP 202
Query: 501 GAFSAMGMGHLLASVAGGGNGGGGGPGT---AAGLDAGGLGPAASAAST 546
+ G G S AGG +GGGGGPGT + G G P A+AA +
Sbjct: 203 PGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGS 251
Score = 31.6 bits (70), Expect = 2.7
Identities = 29/71 (40%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
Query: 3 EPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAA 62
EPA AASA A + A ++ A A+P P G P + L AAA
Sbjct: 67 EPA-AASAGAPAAMLSDTDAGDAFASAAAVAKPG------PPDGRKGSPCGEEELPSAAA 119
Query: 63 AAAAAAAAAEA 73
AAAAAAAAA A
Sbjct: 120 AAAAAAAAAAA 130
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 189 bits (481), Expect = 6e-48
Identities = 116/274 (42%), Positives = 150/274 (54%), Gaps = 15/274 (5%)
Query: 24 FPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPH 83
+P A + A F A A PP A P AG + A A + G +A P
Sbjct: 58 YPGGALVPAPPSRFLGAYAYPPRPQAAGFPG---AGESFPPPADAEGYQPGEGYAA--PD 112
Query: 84 PPAAHL---RSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKV 140
P A R +L EV +V L LW +F++ TEM+ITK GRRMFP
Sbjct: 113 PRAGLYPGPREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSF 172
Query: 141 RVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQW 199
V+GL+ + Y + +D+V D +++ + +W+ GKA+ MP R+Y+HPDSP TG W
Sbjct: 173 TVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHW 232
Query: 200 MAKPVAFHKLKLTNNISDKHGFT---ILNSMHKYQPRFHIVRAND---ILKLPYSTFRTY 253
M + V+F KLKLTNN + T +L S+HKYQPR HIV ND S +
Sbjct: 233 MRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIF 292
Query: 254 VFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRD 287
F ET FIAVTAYQN +ITQLKIDNNPFAKGFR+
Sbjct: 293 TFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE 326
>gi|5730081 T-box, brain, 1 [Homo sapiens]
Length = 682
Score = 185 bits (469), Expect = 1e-46
Identities = 96/189 (50%), Positives = 125/189 (66%), Gaps = 7/189 (3%)
Query: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
+V L + LW +FH+ TEM+ITK GRRMFP +SGLD A Y + +D++ AD +
Sbjct: 205 QVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHW 264
Query: 166 KFHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMAKPVAFHKLKLTNN--ISDKHG-F 221
+F +W+ GKAD + R+Y+HPDSP TG WM + ++F KLKLTNN S+ +G
Sbjct: 265 RFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQM 324
Query: 222 TILNSMHKYQPRFHIVRANDILKLPYS---TFRTYVFPETDFIAVTAYQNDKITQLKIDN 278
+L S+HKYQPR H+V N+ S +T+ FPET FIAVTAYQN ITQLKID+
Sbjct: 325 VVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDH 384
Query: 279 NPFAKGFRD 287
NPFAKGFRD
Sbjct: 385 NPFAKGFRD 393
>gi|4827024 T-box 19 [Homo sapiens]
Length = 448
Score = 179 bits (453), Expect = 1e-44
Identities = 91/192 (47%), Positives = 120/192 (62%), Gaps = 5/192 (2%)
Query: 96 EPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLM 155
E D E ++ LE LW +F ++ EM++TK+GRRMFP K+ V+GLD A Y LL+
Sbjct: 32 EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91
Query: 156 DIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNI 215
D V D R+K+ N W+ AGK + +YIHPDSP G WM P++F K+KLTN +
Sbjct: 92 DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151
Query: 216 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLK 275
+ G +LNS+HKY+P+ HIVR ++ FPET FIAVTAYQN++IT LK
Sbjct: 152 NG-GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALK 206
Query: 276 IDNNPFAKGFRD 287
I NPFAK F D
Sbjct: 207 IKYNPFAKAFLD 218
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 169 bits (429), Expect = 6e-42
Identities = 98/221 (44%), Positives = 130/221 (58%), Gaps = 16/221 (7%)
Query: 134 MFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKF--HNSRWMVAGKADPE-MPKRMYIHP 190
MFP +V+V GLD +Y + +D+V D RY++ H+S+WMVAG D + R Y+HP
Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60
Query: 191 DSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVR------ANDILK 244
DSP +GE WM + ++F ++KLTNN D G IL SMHKY+PR H++ + I
Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120
Query: 245 LPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQL-TLPS 303
LP +T+ F ET+F VTAYQN +IT+LKI+ NPFAKGFRDTG R L T P
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 180
Query: 304 LRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPL 344
+ K GA++ + S P TS G APSPL
Sbjct: 181 RPSFTLDFK--TFGADTQSGS----SGSSPVTSSGGAPSPL 215
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
Query: 504 SAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPFPFHL----SQHML 559
+A + AS G GGG G G AG+ G A + A P + + S+
Sbjct: 332 AAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSF 391
Query: 560 ASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGS 605
P GGLFP+PYT+ AAAAA + A AAA A G+
Sbjct: 392 GGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGA 437
Score = 39.3 bits (90), Expect = 0.013
Identities = 54/200 (27%), Positives = 71/200 (35%), Gaps = 14/200 (7%)
Query: 489 LFLHPGQFTMGPGAFSAMGM---GHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAAS 545
LF HP F AFS A GG GG G AGL GL A
Sbjct: 404 LFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL--SGLFWPAGRKD 461
Query: 546 TAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASAL--PATSAAAAAAAAA 603
P PF + G+P+PT+ P P + + A + AL A A AA
Sbjct: 462 AFYP-PFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAA 520
Query: 604 GSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGG---NSREPSPLP 660
GS +P G + P P PP+ + E G ++ P
Sbjct: 521 GSAEAAPPPGQPPQVVANGPGSGPP--PPAGGAGSRDALFESPPGGSGGDCSAGSTPPAD 578
Query: 661 ELALRKVGAPSRGALSPSGS 680
+A GA + G+ P+GS
Sbjct: 579 SVAAAGAGAAAAGS-GPAGS 597
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
Query: 504 SAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPFPFHL----SQHML 559
+A + AS G GGG G G AG+ G A + A P + + S+
Sbjct: 332 AAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSF 391
Query: 560 ASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGS 605
P GGLFP+PYT+ AAAAA + A AAA A G+
Sbjct: 392 GGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGA 437
Score = 39.3 bits (90), Expect = 0.013
Identities = 54/200 (27%), Positives = 71/200 (35%), Gaps = 14/200 (7%)
Query: 489 LFLHPGQFTMGPGAFSAMGM---GHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAAS 545
LF HP F AFS A GG GG G AGL GL A
Sbjct: 404 LFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL--SGLFWPAGRKD 461
Query: 546 TAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASAL--PATSAAAAAAAAA 603
P PF + G+P+PT+ P P + + A + AL A A AA
Sbjct: 462 AFYP-PFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAA 520
Query: 604 GSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGG---NSREPSPLP 660
GS +P G + P P PP+ + E G ++ P
Sbjct: 521 GSAEAAPPPGQPPQVVANGPGSGPP--PPAGGAGSRDALFESPPGGSGGDCSAGSTPPAD 578
Query: 661 ELALRKVGAPSRGALSPSGS 680
+A GA + G+ P+GS
Sbjct: 579 SVAAAGAGAAAAGS-GPAGS 597
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
Query: 504 SAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPFPFHL----SQHML 559
+A + AS G GGG G G AG+ G A + A P + + S+
Sbjct: 332 AAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSF 391
Query: 560 ASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGS 605
P GGLFP+PYT+ AAAAA + A AAA A G+
Sbjct: 392 GGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGA 437
Score = 39.3 bits (90), Expect = 0.013
Identities = 54/200 (27%), Positives = 71/200 (35%), Gaps = 14/200 (7%)
Query: 489 LFLHPGQFTMGPGAFSAMGM---GHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAAS 545
LF HP F AFS A GG GG G AGL GL A
Sbjct: 404 LFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL--SGLFWPAGRKD 461
Query: 546 TAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASAL--PATSAAAAAAAAA 603
P PF + G+P+PT+ P P + + A + AL A A AA
Sbjct: 462 AFYP-PFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAA 520
Query: 604 GSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGG---NSREPSPLP 660
GS +P G + P P PP+ + E G ++ P
Sbjct: 521 GSAEAAPPPGQPPQVVANGPGSGPP--PPAGGAGSRDALFESPPGGSGGDCSAGSTPPAD 578
Query: 661 ELALRKVGAPSRGALSPSGS 680
+A GA + G+ P+GS
Sbjct: 579 SVAAAGAGAAAAGS-GPAGS 597
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 52.8 bits (125), Expect = 1e-06
Identities = 92/376 (24%), Positives = 114/376 (30%), Gaps = 68/376 (18%)
Query: 320 SDASSCDPPPAREPPTSPGAAPSPLRLHRAR--------------------AEEKSCAAD 359
S A + PA +PGAAP P RAR A AA
Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
Query: 360 SDPEPE----RLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDG 415
P PE + A A + P P A P + P R P G P G G
Sbjct: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185
Query: 416 PF-----GLRSLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASP---------LG 461
P G A A G A L+ A+P +G
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
Query: 462 AGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFTMGPG-----AFSAMGMGHLLASVA 516
A P A S P A P P PG +A + A+
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305
Query: 517 GGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPFPFHLSQ-------------HMLASQG 563
GG G P AAG AG G A+ AAP P ++ LA+ G
Sbjct: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365
Query: 564 --------IPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGSA 615
+ PT G P P AA A P AA A SLSR+P ++
Sbjct: 366 PASTAASMVIGPTMQGALPSP----AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTS 421
Query: 616 RPRLRFSPYQIPVTIP 631
R +P + +P
Sbjct: 422 GIRATLTPTVLAPRLP 437
Score = 42.7 bits (99), Expect = 0.001
Identities = 98/365 (26%), Positives = 127/365 (34%), Gaps = 56/365 (15%)
Query: 367 LSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPF--GLRSLEK 424
+S AGA AP +P EP P G+ A GG GP G S +
Sbjct: 63 VSGSPAGAAGAGPAAPAEGAPGAAPEP--------PPAGR--ARPGGGGPQRPGPPSPRR 112
Query: 425 ERAEARRKDEGRK--EAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGP 482
A K EG AP+ +A+ + AG P A GP
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPV----PAAAAVAAGPEPAPA-----------GP 157
Query: 483 LGAGQPLFLHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAAS 542
P L GPG G G G G G GPG A L+ G +
Sbjct: 158 AKPAGPAALAA---RAGPGPGPGPGPG------PGPGPGKPAGPGAAQTLN--GSAALLN 206
Query: 543 AASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAA 602
+ AAP ++ A +P P G ++ AAA A A P+ AA A AA
Sbjct: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAP 266
Query: 603 AGSLSRSPFLGS--ARP--RLRFSPYQIPVTIPPSTSLL--TTGLASEGSKAAGGN---S 653
A + P + ARP P P PP+ + + G A + AAGG S
Sbjct: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
Query: 654 REPSPLPELALR----KVGAPSR--GALSPSGSAKEAANELQSIQRLVSGLESQRAL-SP 706
+P P A K +P R A P+ A+ + +V G Q AL SP
Sbjct: 327 GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP 386
Query: 707 GRESP 711
P
Sbjct: 387 AAVPP 391
Score = 39.7 bits (91), Expect = 0.010
Identities = 96/419 (22%), Positives = 145/419 (34%), Gaps = 78/419 (18%)
Query: 318 AESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPEPERLSEERAGAPLG 377
A A + PPA P +P AAP P P P L+ P G
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPP----------------PPPAPATLAR-----PPG 285
Query: 378 RSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLRSLEKERAEARRKDEGRK 437
P +A+P + P A+ S PA + G GP G+ A A G K
Sbjct: 286 HPAGPPTAAPA-VPPPAAAQNGGSAGAAPAPAPAAG-GPAGVSGQPGPGAAAAAPAPGVK 343
Query: 438 EAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFT 497
+ + AP QT +AS P +S + G G L + P + P
Sbjct: 344 AESPKRVVQAAPPAAQTLAASG------PASTAASMVIGPTMQGALPS--PAAVPP---- 391
Query: 498 MGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAP--FPFHLS 555
PG + + G A+ A + T +G+ A L P A P P ++
Sbjct: 392 PAPGTPTGLPKG---AAGAVTQSLSRTPTATTSGIRA-TLTPTVLAPRLPQPPQNPTNIQ 447
Query: 556 QHMLASQGIPMPTFGG-LFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGS 614
L + + + G L P +A A A A P T+ A P +
Sbjct: 448 NFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP-----------RPATPT 496
Query: 615 ARPRLRFSPYQIPVT------IPPSTSLLTTGLASEGSKAAGGNSREPSPLPELALR--- 665
+ P ++ S Q P T + P+T + A + + R P P+L L
Sbjct: 497 SAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556
Query: 666 -----------KVGAPSR---GALSPSGSAKEAANELQSIQRLVSGLESQRALSPGRES 710
+ G P R GA + S +A E ++ + +S L + S G++S
Sbjct: 557 QTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTL--IKLASSGKQS 613
Score = 33.5 bits (75), Expect = 0.70
Identities = 33/81 (40%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 18 APRPADFPMSAFLAAAQPSFFPA---LALPPGALAKP------LPDPGLA--GAAAAAAA 66
AP P P A AAA P PA LA PPG A P +P P A G +A AA
Sbjct: 254 APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAP 313
Query: 67 AAAAAEAGLHVSALGPHPPAA 87
A A A G + P P AA
Sbjct: 314 APAPAAGGPAGVSGQPGPGAA 334
Score = 32.7 bits (73), Expect = 1.2
Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 39 PALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPA 86
PA PP A +P P+ G AG+ A AAAA A AG + GP PA
Sbjct: 116 PAGPAPPAAKLRPPPE-GSAGSCAPVPAAAAVA-AGPEPAPAGPAKPA 161
Score = 30.8 bits (68), Expect = 4.5
Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 6 LAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAA 65
L SA + HA PA ++ AA P PA PG + + P G A A AA
Sbjct: 198 LNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA---PGTVIQTPPFVGAAAPPAPAA 254
Query: 66 AAAAAAEAGLHVSALGPHPPAA 87
+ AA A +A P PP A
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPA 276
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 10/156 (6%)
Query: 308 EEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPEPERL 367
EE K E G E +A + + PP A+P + E KS A PE E
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEE-TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538
Query: 368 SE--ERAGAPLGRSPAPDSA-SPTRLTEPERAR-----ERRSPERGKEPAESGGDGPFGL 419
E +SPA + A SP PE+ E +SPE+ K PA+ P
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 420 RSLEKERAEARRKDEGRKEA-AEGKEQGLAPLVVQT 454
+S EK ++ + + + EA + KE+ +P V++
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Score = 50.8 bits (120), Expect = 4e-06
Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 18/162 (11%)
Query: 313 PERDGAESDASSCDPP----PAREPPTSPGAAPSPLRLH-RARAEEKSCAADSDPEPERL 367
PE++ A+S A P PA+E SP A SP + ++ AE KS P E
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 368 -------SEERAGAPL---GRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPF 417
S E+A +P+ +SPA ++ SP + E + E +SPE+ K P + P
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPA-EAKSPVK-EEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Query: 418 GLRSLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASP 459
+S EKE A++ K + + AE K A V+ ++ SP
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVK-AEAKSPEKAKSPVKAEAKSP 691
Score = 47.4 bits (111), Expect = 5e-05
Identities = 46/171 (26%), Positives = 77/171 (45%), Gaps = 19/171 (11%)
Query: 294 EKRKQLTLPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEE 353
EK K T + E+ PE++ A+S + P A SP A SP++ A++ E
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK--SPEKAKSPVKAE-AKSPE 692
Query: 354 KSCAADSDPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGG 413
K A S + E S E+A +P+ ++ SP + P + E ++PE+ K P +
Sbjct: 693 K---AKSPVKEEAKSPEKAKSPVKE----EAKSPEKAKSPVK-EEAKTPEKAKSPVKEEA 744
Query: 414 DGPFGLRSLEKER--------AEARRKDEGRKEAAEGKEQGLAPLVVQTDS 456
P +S EK + A+ K+E R A + E+ +P+ + S
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 10/148 (6%)
Query: 294 EKRKQLTLPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEE 353
EK K + E+ P ++ A+S + P +E SP A SP++ A+ E
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA--KSPVKEEAKSPEKAKSPVK-EEAKTPE 734
Query: 354 KSCAADSDPEPERLSEERAGAPLGRSPAPDSASPTRLT---EPERARERRSPERGKEPAE 410
K A S + E S E+A +P ++ D SP T E R+ + PE+ K P +
Sbjct: 735 K---AKSPVKEEAKSPEKAKSP-EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 411 SGGDGPFGLRSLEKERAEARRKDEGRKE 438
P +S KE A+A K+ +KE
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
Query: 352 EEKSCAADSDPEPERLSEERA--GAPLGRSP-APDSASPTRLTEPERARERRSPERGKEP 408
EEK + E E EE A G +SP A ++ASP + + E +SP K P
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 409 AESGGDGPFGLRSLEKERAEARRKDEGRKEA-AEGKEQGLAPLVVQT 454
+ P ++S EK ++ A+ + + EA + KE+ +P V++
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580
Score = 36.2 bits (82), Expect = 0.11
Identities = 34/154 (22%), Positives = 68/154 (44%), Gaps = 4/154 (2%)
Query: 294 EKRKQLTLPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLH-RARAE 352
EK K + E+ P ++ A+S + P A+ A +P + R+ A+
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 353 EKSCAADSDPEPERLSEERAGAPLGR-SPAPDSASPTR--LTEPERARERRSPERGKEPA 409
+ A S + E S E+A +PL + AP+ P + + P + E+ + KEP
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 410 ESGGDGPFGLRSLEKERAEARRKDEGRKEAAEGK 443
+ + +E+ ++++++ +KEA + K
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873
Score = 33.1 bits (74), Expect = 0.92
Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 10/144 (6%)
Query: 304 LRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPE 363
+++ E K E + A + + + +++ AP P + EEK A P+
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP------KVEEKKEPAVEKPK 886
Query: 364 PERLSEERAGAPLGRS-PAPDSASPTRLTEPERARERRSPE-RGKEPAESGGDGPFGLRS 421
++ ++ A + P P+ +P ++ E A+ + E KEP ++ P +
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP--SKP 944
Query: 422 LEKERAEARRKDEGRKEAAEGKEQ 445
EK+ A +KD ++A + +E+
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEK 968
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,675,055
Number of Sequences: 37866
Number of extensions: 2053521
Number of successful extensions: 25111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 272
Number of HSP's successfully gapped in prelim test: 988
Number of HSP's that attempted gapping in prelim test: 15571
Number of HSP's gapped (non-prelim): 7215
length of query: 712
length of database: 18,247,518
effective HSP length: 109
effective length of query: 603
effective length of database: 14,120,124
effective search space: 8514434772
effective search space used: 8514434772
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.