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Search of human proteins with 195947378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial
[Homo sapiens]
(480 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 993 0.0
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 451 e-127
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 429 e-120
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 420 e-117
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 379 e-105
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 379 e-105
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 379 e-105
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 378 e-105
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 355 4e-98
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 344 1e-94
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 344 1e-94
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 91 2e-18
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 91 2e-18
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 78 2e-14
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 77 3e-14
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 76 6e-14
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 62 1e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 62 1e-09
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 60 3e-09
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 51 2e-06
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens] 45 2e-04
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens] 45 2e-04
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 44 3e-04
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens] 43 6e-04
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 42 0.001
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 42 0.001
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 42 0.001
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 42 0.002
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 42 0.002
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 40 0.005
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 993 bits (2568), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MLGRFQPFSLVRSFRLGFEACCYPNQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWS 60
MLGRFQPFSLVRSFRLGFEACCYPNQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWS
Sbjct: 1 MLGRFQPFSLVRSFRLGFEACCYPNQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWS 60
Query: 61 QLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPP 120
QLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPP
Sbjct: 61 QLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPP 120
Query: 121 TPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCP 180
TPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCP
Sbjct: 121 TPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCP 180
Query: 181 TLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQ 240
TLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQ
Sbjct: 181 TLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQ 240
Query: 241 YGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPE 300
YGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPE
Sbjct: 241 YGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPE 300
Query: 301 TVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRIT 360
TVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRIT
Sbjct: 301 TVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRIT 360
Query: 361 KLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIR 420
KLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIR
Sbjct: 361 KLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIR 420
Query: 421 IKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL 480
IKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL
Sbjct: 421 IKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL 480
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 451 bits (1161), Expect = e-127
Identities = 216/434 (49%), Positives = 303/434 (69%), Gaps = 1/434 (0%)
Query: 47 QNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTC 106
+NFNFA DVLDQWSQ EK G R PALW V+ KG+E KWSF + LS+KAA++L+ C
Sbjct: 50 KNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPC 109
Query: 107 ALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANE 166
L GDRL +ILP PE + + +AC+R GI F+PG+ QLTAK I Y+LR SKA+CIVA+E
Sbjct: 110 GLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASE 169
Query: 167 AMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFT 226
+AP V S V +CP LKTKLLVS +S++GWL F++L Q A + + + T SQ+PM I+FT
Sbjct: 170 EVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFT 229
Query: 227 KGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQG 286
GTTG PKM ++SQ LG+GF+ R W+DL+ +D++W++ D ++ +V +W G
Sbjct: 230 SGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCG 289
Query: 287 ACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGG 346
ACVF+ M F +T L+ L+ +PITTL + P +Y+ L+Q K Y+FKSL+ C+ G
Sbjct: 290 ACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQ-KDLKRYKFKSLRHCLTGGE 348
Query: 347 PISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENS 406
P++P V+E W+ T L++YEGYGQTE G++CA K ++KP S+GK + PY VQI+DEN
Sbjct: 349 PLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQIIDENG 408
Query: 407 NLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWS 466
N+LPPG+EG IA+R+K +P + ++ + ++ A+ Y+TGDRG+MD DGYFW+
Sbjct: 409 NVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFV 468
Query: 467 GRVDDVANALGQRL 480
GR DDV + G R+
Sbjct: 469 GRADDVIISSGYRI 482
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 429 bits (1102), Expect = e-120
Identities = 206/436 (47%), Positives = 290/436 (66%), Gaps = 1/436 (0%)
Query: 45 VSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSD 104
+ + FNFAKDVLDQW+ EK G + PA W ++ GEE +WSFE + LS+K A+ILS+
Sbjct: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
Query: 105 TCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVA 164
C+L GDR+++ILP PE + +AC+R G +PG+ QLT K I Y+L+ SKA CI+
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
Query: 165 NEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIF 224
N+ +AP V++ S C L +KL+VS+ S +GW + K+L++ A T ++TK + MAIF
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
Query: 225 FTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWF 284
FT GT+G PKM ++ G+G S R W+DL P+DV+W+ D + S+V W
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
Query: 285 QGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAA 344
QGACVF H+P F P ++L LS++PIT + P +Y+ L+Q+ TSY+FKSLK CV+A
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQND-ITSYKFKSLKHCVSA 352
Query: 345 GGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDE 404
G PI+P V E W+ T LDIYEGYGQTET L+C K +K+KP S+GKP P + V+IVD
Sbjct: 353 GEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDV 412
Query: 405 NSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFW 464
N N+LPPG+EG+I I++ N+P L+ ++ + + AS Y+TGDRG MD+DGYFW
Sbjct: 413 NGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFW 472
Query: 465 WSGRVDDVANALGQRL 480
+ R DDV + G R+
Sbjct: 473 FVARADDVILSSGYRI 488
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 420 bits (1079), Expect = e-117
Identities = 201/438 (45%), Positives = 297/438 (67%), Gaps = 2/438 (0%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V + FNFA DVLD WS+LE+ G R P PA W V+ G E KWSFE + + S+KAA++L
Sbjct: 47 QLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVL 106
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
C L GDR+M++LP PE + + +AC+R G +PG QLT K ++Y+L+ S+A+ I
Sbjct: 107 GGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSI 166
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
+ ++++AP V++ ++CP+L+TKLLVSD S GWL+F++L++ A + MRTKS+DP+A
Sbjct: 167 ITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLA 226
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GTTGAPKMVE+SQ G+GF + RRW+ L +D+ W+ D G + +
Sbjct: 227 IYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDT-GWVKAAWTLFSA 285
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W G+C+F+ +P + +LN LS+FPITTL P +++ L+Q T Y+F+SL+ C+
Sbjct: 286 WPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQED-LTRYQFQSLRHCL 344
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
G ++P V E WK T +++YEGYGQ+ET ++CA K +K+K S+GK PPY VQIV
Sbjct: 345 TGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIV 404
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
D+ N+LPPGEEGN+A+RI+ +P + ++ + E+ A++ Y+TGDR MD+DGY
Sbjct: 405 DDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGY 464
Query: 463 FWWSGRVDDVANALGQRL 480
FW+ GR DDV N+ R+
Sbjct: 465 FWFMGRNDDVINSSSYRI 482
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 379 bits (972), Expect = e-105
Identities = 195/437 (44%), Positives = 277/437 (63%), Gaps = 3/437 (0%)
Query: 45 VSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSD 104
V + FNFA VLD W+Q EK+G RGP PA W V+ +G+E KWSF M L+++ A++ +
Sbjct: 45 VPEEFNFASYVLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQ 104
Query: 105 TCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVA 164
TC L GD L ++LP PE + + + C+R GI F+P + L AK I Y+L++SKA+ IV
Sbjct: 105 TCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVT 164
Query: 165 NEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIF 224
+A+A V+S S CP+LKTKLLVSD S +GWLDF+ L++ A P+ T +++K+ DPM IF
Sbjct: 165 IDALASEVDSIASQCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIF 224
Query: 225 FTKGTTGAPKMVEYSQYGLGMGFS-QASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTW 283
FT GTTG PKM ++S +GL + S SR+ L+ +DV W L D+ ++ ++ W
Sbjct: 225 FTSGTTGFPKMAKHS-HGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPW 283
Query: 284 FQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVA 343
G VF+ H+P F + ++ L ++PI +Y+ +LQ FTS RF +L+ C
Sbjct: 284 TAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQD-FTSIRFPALEHCYT 342
Query: 344 AGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVD 403
G + P E+WKR T L +YE YGQ+ETGL+CAT +K+KP +GK PPY VQ++D
Sbjct: 343 GGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID 402
Query: 404 ENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYF 463
+ ++LPP EGNI IRIK +P SL+ + E+ A Y TGDRG MDE+GY
Sbjct: 403 DKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTAKVECGDFYNTGDRGKMDEEGYI 462
Query: 464 WWSGRVDDVANALGQRL 480
+ GR DD+ NA G R+
Sbjct: 463 CFLGRSDDIINASGYRI 479
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 379 bits (972), Expect = e-105
Identities = 190/438 (43%), Positives = 280/438 (63%), Gaps = 2/438 (0%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA+IL
Sbjct: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANIL 97
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I
Sbjct: 98 SGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A
Sbjct: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L ++L +
Sbjct: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILGSLLES 276
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ C+
Sbjct: 277 WTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCL 335
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
A G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQ++
Sbjct: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
D+ N+LPPG EG+I IR+K +P ++ ++ + ++ A+ +L GDRGI DEDGY
Sbjct: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGY 455
Query: 463 FWWSGRVDDVANALGQRL 480
F + GR DD+ N+ G R+
Sbjct: 456 FQFMGRADDIINSSGYRI 473
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 379 bits (972), Expect = e-105
Identities = 190/438 (43%), Positives = 280/438 (63%), Gaps = 2/438 (0%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA+IL
Sbjct: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANIL 97
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I
Sbjct: 98 SGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A
Sbjct: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L ++L +
Sbjct: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILGSLLES 276
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ C+
Sbjct: 277 WTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCL 335
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
A G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQ++
Sbjct: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
D+ N+LPPG EG+I IR+K +P ++ ++ + ++ A+ +L GDRGI DEDGY
Sbjct: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGY 455
Query: 463 FWWSGRVDDVANALGQRL 480
F + GR DD+ N+ G R+
Sbjct: 456 FQFMGRADDIINSSGYRI 473
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 378 bits (970), Expect = e-105
Identities = 189/438 (43%), Positives = 278/438 (63%), Gaps = 2/438 (0%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA++L
Sbjct: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVL 97
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I
Sbjct: 98 SGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A
Sbjct: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L +++
Sbjct: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILCSLMEP 276
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ CV
Sbjct: 277 WALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCV 335
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQI+
Sbjct: 336 TVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQII 395
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
D+ N+LPPG EG+I IR+K +P ++ ++ + ++ A+ +L GDRGI DEDGY
Sbjct: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGY 455
Query: 463 FWWSGRVDDVANALGQRL 480
F + GR DD+ N+ G R+
Sbjct: 456 FQFMGRADDIINSSGYRI 473
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 355 bits (912), Expect = 4e-98
Identities = 169/357 (47%), Positives = 238/357 (66%), Gaps = 1/357 (0%)
Query: 45 VSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSD 104
+ + FNFAKDVLDQW+ EK G + PA W ++ GEE +WSFE + LS+K A+ILS+
Sbjct: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
Query: 105 TCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVA 164
C+L GDR+++ILP PE + +AC+R G +PG+ QLT K I Y+L+ SKA CI+
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
Query: 165 NEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIF 224
N+ +AP V++ S C L +KL+VS+ S +GW + K+L++ A T ++TK + MAIF
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
Query: 225 FTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWF 284
FT GT+G PKM ++ G+G S R W+DL P+DV+W+ D + S+V W
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
Query: 285 QGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAA 344
QGACVF H+P F P ++L LS++PIT + P +Y+ L+Q+ TSY+FKSLK CV+A
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQND-ITSYKFKSLKHCVSA 352
Query: 345 GGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQI 401
G PI+P V E W+ T LDIYEGYGQTET L+C K +K+KP S+GKP P + V++
Sbjct: 353 GEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 344 bits (882), Expect = 1e-94
Identities = 182/438 (41%), Positives = 268/438 (61%), Gaps = 8/438 (1%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA++L
Sbjct: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVL 97
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I
Sbjct: 98 SGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A
Sbjct: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L ++L +
Sbjct: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILGSLLES 276
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ C+
Sbjct: 277 WTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCL 335
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
A G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQ++
Sbjct: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
G+ G A + L+ +C H + ++ A+ +L GDRGI DEDGY
Sbjct: 396 AFVHGSPRAGDLG-FAGTMTLS-----FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGY 449
Query: 463 FWWSGRVDDVANALGQRL 480
F + GR DD+ N+ G R+
Sbjct: 450 FQFMGRADDIINSSGYRI 467
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 344 bits (882), Expect = 1e-94
Identities = 182/438 (41%), Positives = 268/438 (61%), Gaps = 8/438 (1%)
Query: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102
Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA++L
Sbjct: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVL 97
Query: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162
S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I
Sbjct: 98 SGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
Query: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222
VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A
Sbjct: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L ++L +
Sbjct: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILGSLLES 276
Query: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342
W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ C+
Sbjct: 277 WTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCL 335
Query: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402
A G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQ++
Sbjct: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395
Query: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462
G+ G A + L+ +C H + ++ A+ +L GDRGI DEDGY
Sbjct: 396 AFVHGSPRAGDLG-FAGTMTLS-----FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGY 449
Query: 463 FWWSGRVDDVANALGQRL 480
F + GR DD+ N+ G R+
Sbjct: 450 FQFMGRADDIINSSGYRI 467
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 91.3 bits (225), Expect = 2e-18
Identities = 100/437 (22%), Positives = 185/437 (42%), Gaps = 35/437 (8%)
Query: 74 LWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVR 133
+W+ G E + ++ + + + + A+ L + GDR+ I +P +P A LAC R
Sbjct: 129 IWERDEPGTEVRITYRELLETTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACAR 187
Query: 134 LGITFVPGSPQLTAKKIRYQLRMSKAQCIVA-NEAMA--------PVVNSAVSDCPTLKT 184
+G +A+ + ++ +K + ++ N+ + +V+ AV CPT++
Sbjct: 188 IGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQH 247
Query: 185 KLLV---SDKSYDGWLDFKKLIQVAP--PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYS 239
L+ +K + G LD ++A P S+D + + +T G+TG PK + ++
Sbjct: 248 VLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHT 307
Query: 240 QYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCP 299
Q G + + + D QP D+ + D + V G GA L P
Sbjct: 308 QAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYP 367
Query: 300 ET--VLNVLSRFPITTLSANPEMYQELLQH--KCFTSYRFKSLKQCVAAGGPISPGVIED 355
+ R I P + LL++ Y SL+ + G PI+ E
Sbjct: 368 NAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEW 427
Query: 356 WKRI---TKLDIYEGYGQTETGLLCATSKT----IKLKPSSLGKPLPPYIVQIVDENSNL 408
R+ ++ + + + QTETG +C + ++ P+ +P + ++DE ++
Sbjct: 428 LHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSV 487
Query: 409 LPPGEEGNIAIRIKLNQP-----ASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYF 463
+ E N++ + ++Q ++Y H + Y A Y TGD E GY+
Sbjct: 488 V---EGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGY-YFTGDGAYRTEGGYY 543
Query: 464 WWSGRVDDVANALGQRL 480
+GR+DDV N G RL
Sbjct: 544 QITGRMDDVINISGHRL 560
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 91.3 bits (225), Expect = 2e-18
Identities = 107/427 (25%), Positives = 176/427 (41%), Gaps = 43/427 (10%)
Query: 89 ERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAK 148
E + Q+SK A ++ + GD ++I +P P+A + LAC R+G +K
Sbjct: 148 EVLEQVSKLAGVLVKH--GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASK 205
Query: 149 KIRYQLRMSKAQCIV-ANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKK----LI 203
++ ++ K + +V A+ + P V P ++ L + D L + + +
Sbjct: 206 ELSSRIDHVKPKVVVTASFGIEP--GRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAV 263
Query: 204 QVAPPK-----QTYMRTKSQD--------PMAIFFTKGTTGAPKMVEYSQYGLGMGFSQA 250
+AP + + + +S D P+ I +T GTTG PK V G + +
Sbjct: 264 PLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAVMLHWS 323
Query: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVL-GTWFQGACVFLCH-MPTFCPET--VLNVL 306
LQP +V W+ D G + S + G G L P P+ VL
Sbjct: 324 MSSIYGLQPGEVWWAASD-LGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVL 382
Query: 307 SRFPITTLSANPEMYQELLQH-------KCFTSYRFKSLKQCVAAGGPISPGVIEDWKRI 359
+ + L P + + Q K ++ RFK+L AG +E K +
Sbjct: 383 AEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTL---FVAGERCDVETLEWSKNV 439
Query: 360 TKLDIYEGYGQTETGLLCATS-----KTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEE 414
++ + + + QTETG S + P GK +P Y V I+D+N L
Sbjct: 440 FRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCL 499
Query: 415 GNIAIRIKLNQPA-SLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVA 473
GNI +++ L A S + +++ + Y T D G MDE+GY + RVDDV
Sbjct: 500 GNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVI 559
Query: 474 NALGQRL 480
N G R+
Sbjct: 560 NVAGHRI 566
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 78.2 bits (191), Expect = 2e-14
Identities = 107/486 (22%), Positives = 194/486 (39%), Gaps = 63/486 (12%)
Query: 50 NFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALS 109
N +VLD+ +K G + + W+ + GE + ++ ++ + +++L +
Sbjct: 102 NICYNVLDRNVHEKKLGDKVAF--YWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GIQ 158
Query: 110 HGDRLMIILPPTPEAYWICLACVRLG----ITFVPGSPQLTAKKI--------------- 150
GDR+ I +P PE LAC R+G I F S + ++I
Sbjct: 159 KGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFY 218
Query: 151 -----------------RYQLRMSKAQCIVANEAMAPV---VNSAVSDCPTLKTKLLVSD 190
+ Q + +C + + + + + S P +K
Sbjct: 219 RGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ 278
Query: 191 KSYDGWLD--FKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFS 248
S++ +D + +L+Q A + ++DP+ I +T G+TG PK V ++ G + +
Sbjct: 279 ISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVA 338
Query: 249 QASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCH-MPTFCPETVL-NVL 306
+ D DV W D + G GA L +PT+ L +++
Sbjct: 339 TTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIV 398
Query: 307 SRFPITTLSANPEMYQELLQH--KCFTSYRFKSLKQCVAAGGPISPGVIEDWKRIT---K 361
++ +T P + L++ + T + SL+ G PI+P + R+ +
Sbjct: 399 DKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQR 458
Query: 362 LDIYEGYGQTETG--LLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAI 419
I + + QTETG +L +KP S P I++E+ L EG +
Sbjct: 459 CPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVF 518
Query: 420 RIKLNQP-----ASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVAN 474
+ QP ++Y H +E + Y+TGD D+DGY+W +GR+DD+ N
Sbjct: 519 K----QPWPGIMRTVYGNHE-RFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLN 573
Query: 475 ALGQRL 480
G L
Sbjct: 574 VSGHLL 579
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 77.0 bits (188), Expect = 3e-14
Identities = 109/439 (24%), Positives = 175/439 (39%), Gaps = 54/439 (12%)
Query: 82 EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141
E+ + +F ++ + KAAS L + L GDRL + P + + LA + GI V
Sbjct: 96 EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
Query: 142 SPQLTAKKIRYQLRMSKAQCIV------------ANEAMAPVVNSAVSDC------PTLK 183
+P A ++ Y L+ + +V + + P V +A P L
Sbjct: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
Query: 184 TKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTK-------SQDPMAIFFTKGTTGAPKMV 236
T + V D G L +++ +Q + + DP+ I FT GTTG+PK
Sbjct: 215 TVISV-DAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGA 273
Query: 237 EYSQYGLGMGFSQASRRWM--DLQPTDVLWSLGDAFGGSL-SLSAVLGTWFQGACVFLCH 293
S Y + + R + P + L + L S++ + GA + L
Sbjct: 274 TLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS 333
Query: 294 MPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVI 353
P F + L +SR T L P M+ ++L F+SY ++ V AG P P +I
Sbjct: 334 -PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELI 392
Query: 354 ED-WKRITKLDIYEGYGQTETGLLCAT---SKTIKLKPSSLGKPLPPYIVQIVDENSNLL 409
+I D+ YG TE + T++ K S+G+ +P +I++
Sbjct: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNM----- 447
Query: 410 PPGEEGNIAIRIKLNQPASL----YCPHMVSWEEYASARGHM----LYLTGDRGIMDEDG 461
E G +A KLN P L YC + W E + Y TGD M+E G
Sbjct: 448 ---EAGTLA---KLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQG 501
Query: 462 YFWWSGRVDDVANALGQRL 480
+ GR D+ G+ +
Sbjct: 502 FCKIVGRSKDMIIRGGENI 520
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 76.3 bits (186), Expect = 6e-14
Identities = 112/500 (22%), Positives = 195/500 (39%), Gaps = 78/500 (15%)
Query: 50 NFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALS 109
N +VLD+ +K G + + W+ + GE + ++ ++ + +++L +
Sbjct: 102 NICYNVLDRNVHEKKLGDKVAF--YWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GIQ 158
Query: 110 HGDRLMIILPPTPEAYWICLACVRLGI------------------------------TFV 139
GDR+ I +P PE LAC R+G F
Sbjct: 159 KGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFY 218
Query: 140 PGSPQLTAKKIRYQLRMSKAQ--------CIVANEAMAPVVNSAVS---------DCPTL 182
G + K++ + + K Q CIV + S CP +
Sbjct: 219 RGEKLVNLKELADEA-LQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
Query: 183 KTKLLVSDK------SYDGWLD--FKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPK 234
+ KL K S++ +D + +L+Q A + ++DP+ I +T G+TG PK
Sbjct: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
Query: 235 MVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCH- 293
V ++ G + + + D DV W D + G GA L
Sbjct: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397
Query: 294 MPTFCPETVL-NVLSRFPITTLSANPEMYQELLQH--KCFTSYRFKSLKQCVAAGGPISP 350
+PT+ L +++ ++ +T P + L++ + T + SL+ G PI+P
Sbjct: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457
Query: 351 GVIEDWKRIT---KLDIYEGYGQTETG--LLCATSKTIKLKPSSLGKPLPPYIVQIVDEN 405
+ R+ + I + + QTETG +L +KP S P I++E+
Sbjct: 458 EAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNES 517
Query: 406 SNLLPPGEEGNIAIRIKLNQP-----ASLYCPHMVSWEEYASARGHMLYLTGDRGIMDED 460
L EG + + QP ++Y H +E + Y+TGD D+D
Sbjct: 518 GEELEGEAEGYLVFK----QPWPGIMRTVYGNHE-RFETTYFKKFPGYYVTGDGCQRDQD 572
Query: 461 GYFWWSGRVDDVANALGQRL 480
GY+W +GR+DD+ N G L
Sbjct: 573 GYYWITGRIDDMLNVSGHLL 592
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 62.0 bits (149), Expect = 1e-09
Identities = 73/289 (25%), Positives = 111/289 (38%), Gaps = 59/289 (20%)
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I +T GTTG PK V + + + +W W+ D L L V G
Sbjct: 199 IIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA--------WTKDDVILHVLPLHHVHGV 250
Query: 283 --------WFQGACVFLCHMPTFCPETVLN--VLSRFP-ITTLSANPEMYQELLQH--KC 329
W CV MP F P+ V + S P I A P +Y +L+++ +
Sbjct: 251 VNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRH 307
Query: 330 FTSYRFKS---------LKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATS 380
FT + ++ V+ + V+E WK IT + E YG TE G+ +
Sbjct: 308 FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGP 367
Query: 381 KTIKLK-PSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEE 439
T ++ P S+G PLP V+IV EN P E + I + ++ + P E
Sbjct: 368 LTTAVRLPGSVGTPLPGVQVRIVSEN----PQREACSYTIHAEGDERGTKVTPGFEEKEG 423
Query: 440 YASARGHML--------------------YLTGDRGIMDEDGYFWWSGR 468
RG + + TGD ++ +DG +W GR
Sbjct: 424 ELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGR 471
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 62.0 bits (149), Expect = 1e-09
Identities = 73/289 (25%), Positives = 111/289 (38%), Gaps = 59/289 (20%)
Query: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282
I +T GTTG PK V + + + +W W+ D L L V G
Sbjct: 199 IIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA--------WTKDDVILHVLPLHHVHGV 250
Query: 283 --------WFQGACVFLCHMPTFCPETVLN--VLSRFP-ITTLSANPEMYQELLQH--KC 329
W CV MP F P+ V + S P I A P +Y +L+++ +
Sbjct: 251 VNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRH 307
Query: 330 FTSYRFKS---------LKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATS 380
FT + ++ V+ + V+E WK IT + E YG TE G+ +
Sbjct: 308 FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGP 367
Query: 381 KTIKLK-PSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEE 439
T ++ P S+G PLP V+IV EN P E + I + ++ + P E
Sbjct: 368 LTTAVRLPGSVGTPLPGVQVRIVSEN----PQREACSYTIHAEGDERGTKVTPGFEEKEG 423
Query: 440 YASARGHML--------------------YLTGDRGIMDEDGYFWWSGR 468
RG + + TGD ++ +DG +W GR
Sbjct: 424 ELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGR 471
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 60.5 bits (145), Expect = 3e-09
Identities = 89/431 (20%), Positives = 172/431 (39%), Gaps = 47/431 (10%)
Query: 83 EDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGS 142
++ ++ ++ + S + A L D L GD + +++ P W+ L V+LG +
Sbjct: 76 DETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLN 135
Query: 143 PQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSD-CPTLK--------TKLLVSDKSY 193
+ AK + + + A+ ++ ++P + +AV + P+LK +
Sbjct: 136 YNIRAKSLLHCFQCCGAKVLL----VSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGI 191
Query: 194 DGWLDFKKLIQVAP-PKQTYMRTKSQDPMAIFFTKGTTGAPK--MVEYSQYGLGMGFSQA 250
D +LD + P P+ P +T GTTG PK M+ + + G G +
Sbjct: 192 DSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFV 251
Query: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
S L+ DV++ + + L + G GA + L F + ++
Sbjct: 252 S----GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLAL--RTKFSASQFWDDCRKYN 305
Query: 311 ITTLSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEG 367
+T + + ELL++ C + + + K +A G + V + KR + IYE
Sbjct: 306 VTVI----QYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEF 361
Query: 368 YGQTETGL--------LCATSKTIKLKPSSLGKPLPPYIVQ----IVDENSNL--LPPGE 413
Y TE + + A + L+ + L Y V+ + DEN +P GE
Sbjct: 362 YAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGE 421
Query: 414 EGNIAIRIKLNQPASLYCPHMVSWEEY----ASARGHMLYLTGDRGIMDEDGYFWWSGRV 469
G + +I P + Y E+ +G + + +GD ++D + + ++ RV
Sbjct: 422 VGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRV 481
Query: 470 DDVANALGQRL 480
D G+ +
Sbjct: 482 GDTFRWKGENV 492
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 51.2 bits (121), Expect = 2e-06
Identities = 92/432 (21%), Positives = 163/432 (37%), Gaps = 43/432 (9%)
Query: 81 GEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVP 140
G + W+F ++ S A++ + GD + I L PE + L + G+
Sbjct: 99 GTGECWTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAAL 157
Query: 141 GSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFK 200
+ L + + + L S A+ ++ M V K D +G L
Sbjct: 158 LNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDT 217
Query: 201 KLIQ-------VAPPKQTYMRTKSQDPMAIF-FTKGTTGAPK--MVEYSQYGLGMGFSQA 250
L+ AP Q + +K D + +T GTTG PK +V +S+Y F
Sbjct: 218 HLLDPLLKEASTAPLAQ--IPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHH 275
Query: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
+ R +Q DVL+ + + ++ V G V L F + ++
Sbjct: 276 AYR---MQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVL--RKKFSASRFWDDCIKYN 330
Query: 311 ITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYG 369
T + E+ + LL+ + R ++ +A G + P + E++ +R I E YG
Sbjct: 331 CTVVQYIGEICRYLLKQPVREAERRHRVR--LAVGNGLRPAIWEEFTERFGVRQIGEFYG 388
Query: 370 QTETGLLCATSKTIKLKPSSLGKPLPPYI-----VQIVDENSNLL----------PPGEE 414
TE A K+ + P++ V++ ++ LL GE
Sbjct: 389 ATECNCSIANMDG-KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEP 447
Query: 415 GNIAIRIKLNQPASL---YCPHMVSWEEYASA---RGHMLYLTGDRGIMDEDGYFWWSGR 468
G + +I P Y + ++ A + +G YL+GD +MDE GY ++ R
Sbjct: 448 GLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDR 507
Query: 469 VDDVANALGQRL 480
D G+ +
Sbjct: 508 SGDTFRWRGENV 519
>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
Length = 1567
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/298 (23%), Positives = 119/298 (39%), Gaps = 57/298 (19%)
Query: 46 SQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKA---ASIL 102
++ F F DVL + D +P ++AKG S QL K+A A+ L
Sbjct: 977 ARKFLFLADVLQWRAHTTPD-----HPLFLLLNAKGTVT--STATCVQLHKRAERVAAAL 1029
Query: 103 SDTCALSHGDRLMIILPPTPE---AYWICLACVRLGITFVPGSPQ---LTAKKIRYQLRM 156
+ LS GD + ++ PP + A++ CL C + +T P PQ T ++ + +
Sbjct: 1030 MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1089
Query: 157 SKAQCIVANEAMAPVVNS----AVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTY 212
SK+ C++ +A+ ++ S A D T T L D + KK+ V
Sbjct: 1090 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDD------IPKKKIASV------- 1136
Query: 213 MRTKSQDPMA-IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTD---------- 261
R S D +A + F+ TTG V+ S + ++ + +L P+
Sbjct: 1137 FRPPSPDVLAYLDFSVSTTGILAGVKMS-HAATSALCRSIKLQCELYPSRQIAICLDPYC 1195
Query: 262 ----VLWSLGDAFGG-------SLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSR 308
LW L + G L L + + W + + TFC +V+ + ++
Sbjct: 1196 GLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARV-TFCSYSVMEMCTK 1252
>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
Length = 1571
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/298 (23%), Positives = 119/298 (39%), Gaps = 57/298 (19%)
Query: 46 SQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKA---ASIL 102
++ F F DVL + D +P ++AKG S QL K+A A+ L
Sbjct: 981 ARKFLFLADVLQWRAHTTPD-----HPLFLLLNAKGTVT--STATCVQLHKRAERVAAAL 1033
Query: 103 SDTCALSHGDRLMIILPPTPE---AYWICLACVRLGITFVPGSPQ---LTAKKIRYQLRM 156
+ LS GD + ++ PP + A++ CL C + +T P PQ T ++ + +
Sbjct: 1034 MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1093
Query: 157 SKAQCIVANEAMAPVVNS----AVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTY 212
SK+ C++ +A+ ++ S A D T T L D + KK+ V
Sbjct: 1094 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDD------IPKKKIASV------- 1140
Query: 213 MRTKSQDPMA-IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTD---------- 261
R S D +A + F+ TTG V+ S + ++ + +L P+
Sbjct: 1141 FRPPSPDVLAYLDFSVSTTGILAGVKMS-HAATSALCRSIKLQCELYPSRQIAICLDPYC 1199
Query: 262 ----VLWSLGDAFGG-------SLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSR 308
LW L + G L L + + W + + TFC +V+ + ++
Sbjct: 1200 GLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARV-TFCSYSVMEMCTK 1256
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 43.9 bits (102), Expect = 3e-04
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376
N ++ L+ HK +S + ++ V P+S V+ + YEGYGQTE
Sbjct: 408 NNSLWDRLIFHKVQSSLGGR-VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAG 466
Query: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420
C + +G P+P ++++VD E N + EG + ++
Sbjct: 467 CCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVK 511
>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
Length = 1110
Score = 43.1 bits (100), Expect = 6e-04
Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 34/200 (17%)
Query: 46 SQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKA---ASIL 102
++ F F DVL + D +P ++AKG S QL K+A A+ L
Sbjct: 917 ARKFLFLADVLQWRAHTTPD-----HPLFLLLNAKGTVT--STATCVQLHKRAERVAAAL 969
Query: 103 SDTCALSHGDRLMIILPPTPE---AYWICLACVRLGITFVPGSPQ---LTAKKIRYQLRM 156
+ LS GD + ++ PP + A++ CL C + +T P PQ T ++ + +
Sbjct: 970 MEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEV 1029
Query: 157 SKAQCIVANEAMAPVVNS----AVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTY 212
SK+ C++ +A+ ++ S A D T T L D + KK+ V
Sbjct: 1030 SKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDD------IPKKKIASV------- 1076
Query: 213 MRTKSQDPMA-IFFTKGTTG 231
R S D +A + F+ TTG
Sbjct: 1077 FRPPSPDVLAYLDFSVSTTG 1096
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 42.0 bits (97), Expect = 0.001
Identities = 86/431 (19%), Positives = 157/431 (36%), Gaps = 40/431 (9%)
Query: 80 KGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFV 139
+G + W+F ++ + S A+ L L+ GD I + E + L +LG+
Sbjct: 96 EGTDTHWTFRQLDEYSSSVANFLQAR-GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
Query: 140 PGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSA-VSDCPTLKTKLLVSDKSYDGWL- 197
+ L + + L S+A+ +V MA + S P+L L S G +
Sbjct: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSL--SLFCSGSWEPGAVP 212
Query: 198 ----DFKKLIQVAPPKQTYMRTKS-QDPMAIFFTKGTTGAPK--MVEYSQYGLGMGFSQA 250
L++ AP K D + +T GTTG PK +V +S+Y
Sbjct: 213 PSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYY 272
Query: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
R ++P D+++ + + ++ + G V + F + ++
Sbjct: 273 GFR---MRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVI--RKKFSASRFWDDCIKYN 327
Query: 311 ITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYG 369
T + E+ + LL + ++ +A G + + ++ R + E YG
Sbjct: 328 CTIVQYIGELCRYLLNQPPREAENQHQVR--MALGNGLRQSIWTNFSSRFHIPQVAEFYG 385
Query: 370 QTE----TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLL----------PPGEEG 415
TE G + L P +V++ ++ L+ PGE G
Sbjct: 386 ATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPG 445
Query: 416 NIAIRIKLNQPASLYCPHMVSWEEYAS------ARGHMLYLTGDRGIMDEDGYFWWSGRV 469
+ RI P + ++ +G YLTGD +MDE GY ++ R
Sbjct: 446 QLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRT 505
Query: 470 DDVANALGQRL 480
D G+ +
Sbjct: 506 GDTFRWKGENV 516
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 42.0 bits (97), Expect = 0.001
Identities = 81/428 (18%), Positives = 160/428 (37%), Gaps = 41/428 (9%)
Query: 82 EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141
E D ++++ + + S + A + + +L GD + +++ P+ + +LG
Sbjct: 76 EGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFL 135
Query: 142 SPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLV---SDKSYDGWLD 198
+ + + + +R + +V A ++ + P+L + V D G +
Sbjct: 136 NTNIRSNSLLNCIRACGPRALVVG---ADLLGTVEEILPSLSENISVWGMKDSVPQGVIS 192
Query: 199 FKKLIQVAP----PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRW 254
K+ + +P P+ ++ + + FT GTTG PK SQ + G ++ W
Sbjct: 193 LKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG---SAVLW 249
Query: 255 -MDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITT 313
D+++ + S ++ + G GA L F + ++ +T
Sbjct: 250 AFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVL--KKKFSASQFWSDCKKYDVTV 307
Query: 314 LSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQ 370
+ EL ++ C S R K K +A G I V ++ R + + E Y
Sbjct: 308 F----QYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAA 363
Query: 371 TE--------TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSN------LLPPGEEGN 416
TE TG + A +T L Y Q + N + GE G
Sbjct: 364 TESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGL 423
Query: 417 IAIRIKLNQPASLYC-PHMVSWEEY---ASARGHMLYLTGDRGIMDEDGYFWWSGRVDDV 472
+ R+ P Y P+ + ++ +G + TGD + D+D + ++ R D
Sbjct: 424 LISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDT 483
Query: 473 ANALGQRL 480
G+ +
Sbjct: 484 FRWKGENV 491
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 42.0 bits (97), Expect = 0.001
Identities = 81/428 (18%), Positives = 160/428 (37%), Gaps = 41/428 (9%)
Query: 82 EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141
E D ++++ + + S + A + + +L GD + +++ P+ + +LG
Sbjct: 76 EGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFL 135
Query: 142 SPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLV---SDKSYDGWLD 198
+ + + + +R + +V A ++ + P+L + V D G +
Sbjct: 136 NTNIRSNSLLNCIRACGPRALVVG---ADLLGTVEEILPSLSENISVWGMKDSVPQGVIS 192
Query: 199 FKKLIQVAP----PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRW 254
K+ + +P P+ ++ + + FT GTTG PK SQ + G ++ W
Sbjct: 193 LKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG---SAVLW 249
Query: 255 -MDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITT 313
D+++ + S ++ + G GA L F + ++ +T
Sbjct: 250 AFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVL--KKKFSASQFWSDCKKYDVTV 307
Query: 314 LSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQ 370
+ EL ++ C S R K K +A G I V ++ R + + E Y
Sbjct: 308 F----QYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAA 363
Query: 371 TE--------TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSN------LLPPGEEGN 416
TE TG + A +T L Y Q + N + GE G
Sbjct: 364 TESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGL 423
Query: 417 IAIRIKLNQPASLYC-PHMVSWEEY---ASARGHMLYLTGDRGIMDEDGYFWWSGRVDDV 472
+ R+ P Y P+ + ++ +G + TGD + D+D + ++ R D
Sbjct: 424 LISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDT 483
Query: 473 ANALGQRL 480
G+ +
Sbjct: 484 FRWKGENV 491
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 2/105 (1%)
Query: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376
N ++ EL +K S ++ V P SP V+ + +YEGYGQTE
Sbjct: 433 NDSIWDELFFNKIQASLG-GCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAG 491
Query: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420
C + +G PLP +++VD E N EG I +R
Sbjct: 492 CTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVR 536
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 2/105 (1%)
Query: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376
N ++ EL +K S ++ V P SP V+ + +YEGYGQTE
Sbjct: 433 NDSIWDELFFNKIQASLG-GCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAG 491
Query: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420
C + +G PLP +++VD E N EG I +R
Sbjct: 492 CTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVR 536
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 40.0 bits (92), Expect = 0.005
Identities = 92/404 (22%), Positives = 148/404 (36%), Gaps = 43/404 (10%)
Query: 108 LSHGDRLMIILPPTPEAYWICLACVRLGI--TFVPGSPQLTAKKIRYQLRMSKAQCIVAN 165
LS G + ++LP PE W+ + G+ FVP + L + + LR A+ +V
Sbjct: 211 LSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTA--LRRGPLLHCLRSCGARALV-- 266
Query: 166 EAMAP-VVNSAVSDCPTLKTKLLVSDKSYDGW-------LDFKKLIQVAPPKQTYMRTKS 217
+AP + S D P L+ L + G L + +V P Y+ +
Sbjct: 267 --LAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQ 324
Query: 218 Q--DPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLS 275
D FT GTTG PK S L + Q + + DV++ + S S
Sbjct: 325 SITDTCLYIFTSGTTGLPKAARISH--LKILQCQGFYQLCGVHQEDVIYLALPLYHMSGS 382
Query: 276 LSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRF 335
L ++G GA V L F + +T E+ + L+ + R
Sbjct: 383 LLGIVGCMGIGATVVL--KSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERG 440
Query: 336 KSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQTE--------TGLLCATSKTIKLK 386
++ +A G + P E + +R L + E YG TE TG A + L
Sbjct: 441 HKVR--LAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLY 498
Query: 387 PSSLGKPLPPYIV----QIVDENSNLL--PPGEEGNIAIRIKLNQPASLYC--PHMVSWE 438
L Y V I D + + PGE G + + P Y P + +
Sbjct: 499 KHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGK 558
Query: 439 --EYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL 480
+ G + + TGD + D+ G+ + R D G+ +
Sbjct: 559 LLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENV 602
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,066,144
Number of Sequences: 37866
Number of extensions: 908906
Number of successful extensions: 1845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1757
Number of HSP's gapped (non-prelim): 68
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.