Guide to the Human Genome
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Search of human proteins with 194239701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194239701 tubulin folding cofactor E-like [Homo sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194239701 tubulin folding cofactor E-like [Homo sapiens]           856   0.0  
gi|194239699 tubulin folding cofactor E-like [Homo sapiens]           856   0.0  
gi|118442828 beta-tubulin cofactor E [Homo sapiens]                   127   2e-29
gi|4507375 beta-tubulin cofactor E [Homo sapiens]                     127   2e-29
gi|66472382 nischarin [Homo sapiens]                                   50   4e-06
gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens]             45   2e-04
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap...    44   2e-04
gi|164607156 axonemal dynein light chain 1 [Homo sapiens]              43   6e-04
gi|21389483 leucine-rich repeats and guanylate kinase domain con...    42   0.001
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]              41   0.002
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]              41   0.002
gi|21389431 leucine rich repeat containing 39 [Homo sapiens]           40   0.003
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...    40   0.003
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...    40   0.003
gi|4503743 flightless I homolog [Homo sapiens]                         40   0.004
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]             40   0.005
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]             40   0.005
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]             40   0.005
gi|31621309 leucine rich repeat containing 6 [Homo sapiens]            39   0.007
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo...    38   0.020
gi|20143971 toll-like receptor 6 [Homo sapiens]                        37   0.026
gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]         37   0.026
gi|15487670 nuclear RNA export factor 1 isoform 1 [Homo sapiens]       37   0.034
gi|41350337 toll-like receptor 1 [Homo sapiens]                        37   0.034
gi|42822866 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034
gi|42822864 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034
gi|42822868 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034
gi|42822870 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034
gi|42822874 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034
gi|42794608 ribonuclease/angiogenin inhibitor [Homo sapiens]           37   0.034

>gi|194239701 tubulin folding cofactor E-like [Homo sapiens]
          Length = 424

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI 60
           MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI
Sbjct: 1   MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI 60

Query: 61  TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT 120
           TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT
Sbjct: 61  TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT 120

Query: 121 CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH 180
           CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH
Sbjct: 121 CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH 180

Query: 181 ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ 240
           ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ
Sbjct: 181 ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ 240

Query: 241 SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS 300
           SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS
Sbjct: 241 SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS 300

Query: 301 ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR 360
           ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR
Sbjct: 301 ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR 360

Query: 361 LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE 420
           LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE
Sbjct: 361 LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE 420

Query: 421 SKTK 424
           SKTK
Sbjct: 421 SKTK 424


>gi|194239699 tubulin folding cofactor E-like [Homo sapiens]
          Length = 424

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI 60
           MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI
Sbjct: 1   MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGI 60

Query: 61  TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT 120
           TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT
Sbjct: 61  TCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERT 120

Query: 121 CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH 180
           CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH
Sbjct: 121 CAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLH 180

Query: 181 ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ 240
           ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ
Sbjct: 181 ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ 240

Query: 241 SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS 300
           SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS
Sbjct: 241 SWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDS 300

Query: 301 ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR 360
           ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR
Sbjct: 301 ERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIR 360

Query: 361 LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE 420
           LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE
Sbjct: 361 LDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVE 420

Query: 421 SKTK 424
           SKTK
Sbjct: 421 SKTK 424


>gi|118442828 beta-tubulin cofactor E [Homo sapiens]
          Length = 527

 Score =  127 bits (319), Expect = 2e-29
 Identities = 102/397 (25%), Positives = 184/397 (46%), Gaps = 37/397 (9%)

Query: 55  LNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNL 114
           L +C ++CAG++  +A  C ++ ++DLS N L  W EV  I   +  LE LN+S N L  
Sbjct: 134 LRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKF 193

Query: 115 ---SVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSI 171
              SVL     G+ S ++ LVLN +  +W  V   +   P LEEL+L  N+      P+ 
Sbjct: 194 PSGSVL----TGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNNIFISERPTD 249

Query: 172 CCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLA---RLFPN 228
              ++KLL ++ N L D  ++  +  + P L+ L+L++  ++++  PD  +     +FP+
Sbjct: 250 VLQTVKLLDLSSNQLIDENQLYLIAHL-PRLEQLILSDTGISSLHFPDAGIGCKTSMFPS 308

Query: 229 LRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLL-QPYTTEERRKLVIARLPSVSKL 287
           L+ + ++ + +  W   ++L   P L  +  L  PL  +    E  R L+IA +  +  L
Sbjct: 309 LKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTL 368

Query: 288 NGSVVTDGEREDSERFFIRYYVDV---------PQEE--------VPFRYHELITKYGKL 330
           N   +   ER  +E  + + + +          P++            RY  L  KYG  
Sbjct: 369 NKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAP 428

Query: 331 E--------PLAEVDLRPQSSAKVEVHFNDQVEEMSIRLDQTVAELKKQLKTLVQLPTSN 382
           E        PL   +       K     + +V E  +    T+ ++K  L  L+++P S+
Sbjct: 429 EDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSD 488

Query: 383 MLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYV 419
           +LL Y   + P    E++   ++L  + + +GD + V
Sbjct: 489 LLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLV 525


>gi|4507375 beta-tubulin cofactor E [Homo sapiens]
          Length = 527

 Score =  127 bits (319), Expect = 2e-29
 Identities = 102/397 (25%), Positives = 184/397 (46%), Gaps = 37/397 (9%)

Query: 55  LNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNL 114
           L +C ++CAG++  +A  C ++ ++DLS N L  W EV  I   +  LE LN+S N L  
Sbjct: 134 LRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKF 193

Query: 115 ---SVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSI 171
              SVL     G+ S ++ LVLN +  +W  V   +   P LEEL+L  N+      P+ 
Sbjct: 194 PSGSVL----TGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNNIFISERPTD 249

Query: 172 CCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLA---RLFPN 228
              ++KLL ++ N L D  ++  +  + P L+ L+L++  ++++  PD  +     +FP+
Sbjct: 250 VLQTVKLLDLSSNQLIDENQLYLIAHL-PRLEQLILSDTGISSLHFPDAGIGCKTSMFPS 308

Query: 229 LRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLL-QPYTTEERRKLVIARLPSVSKL 287
           L+ + ++ + +  W   ++L   P L  +  L  PL  +    E  R L+IA +  +  L
Sbjct: 309 LKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTL 368

Query: 288 NGSVVTDGEREDSERFFIRYYVDV---------PQEE--------VPFRYHELITKYGKL 330
           N   +   ER  +E  + + + +          P++            RY  L  KYG  
Sbjct: 369 NKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAP 428

Query: 331 E--------PLAEVDLRPQSSAKVEVHFNDQVEEMSIRLDQTVAELKKQLKTLVQLPTSN 382
           E        PL   +       K     + +V E  +    T+ ++K  L  L+++P S+
Sbjct: 429 EDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSD 488

Query: 383 MLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYV 419
           +LL Y   + P    E++   ++L  + + +GD + V
Sbjct: 489 LLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLV 525


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 33/170 (19%)

Query: 59  GITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLE 118
           G T  G    +      ++ LDLS N +    E+ + V  +P++EFL+LS N L      
Sbjct: 272 GTTLEGPVTAVIPTWQALTTLDLSHNSIS---EIDESVKLIPKIEFLDLSHNGL------ 322

Query: 119 RTCAGSFSGVRKLVLNNSKASWETVHMIL--QELPDLEELFLCLNDYETVSCPSICCHSL 176
                       LV++N +  +  VH+ L   +L  LE L   L + +T++       SL
Sbjct: 323 ------------LVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESL 370

Query: 177 KLLH---------ITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEE 217
             LH         + DN ++   E+R +G + P L+ + L NN L+ I +
Sbjct: 371 SGLHKLYSLVNLDLRDNRIEQMEEVRSIGSL-PCLEHVSLLNNPLSIIPD 419


>gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens]
          Length = 716

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 44/183 (24%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGV---RKLV 132
           +  L   DNKL    +++  +  VP L+FL+L+ NP++     +   G F  +   ++L 
Sbjct: 241 LESLSFYDNKLVKVPQLA--LQKVPNLKFLDLNKNPIH-----KIQEGDFKNMLRLKELG 293

Query: 133 LNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSIC-CHSLKLLHITDNNLQDWTE 191
           +NN           L  LP+L +L       E  + P +   H L    +          
Sbjct: 294 INNMGELVSVDRYALDNLPELTKL-------EATNNPKLSYIHRLAFRSV---------- 336

Query: 192 IRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQ-----SWEDID 246
                   P+L++L+L NN LNAI +         PNLR IS+H + L+      W + +
Sbjct: 337 --------PALESLMLNNNALNAIYQ---KTVESLPNLREISIHSNPLRCDCVIHWINSN 385

Query: 247 KLN 249
           K N
Sbjct: 386 KTN 388



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 46/188 (24%)

Query: 52  VLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNP 111
           VL+L S  I    DE +      +++ELD S N   +  EV   ++N+ QL  L+L  N 
Sbjct: 76  VLLLQSNNIAKTVDELQQLF---NLTELDFSQNNFTNIKEVG--LANLTQLTTLHLEENQ 130

Query: 112 LNLSVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSI 171
           +                            E     LQ+L +L+EL++  N   T+S  + 
Sbjct: 131 IT---------------------------EMTDYCLQDLSNLQELYINHNQISTISAHAF 163

Query: 172 C-CHSLKLLHITDNNLQ----DWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLF 226
               +L  LH+  N L+     W +        P+L+ L++  N +  I    D   +  
Sbjct: 164 AGLKNLLRLHLNSNKLKVIDSRWFD------STPNLEILMIGENPVIGIL---DMNFKPL 214

Query: 227 PNLRSISL 234
            NLRS+ L
Sbjct: 215 ANLRSLVL 222


>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
           sapiens]
          Length = 360

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 58/247 (23%), Positives = 115/247 (46%), Gaps = 44/247 (17%)

Query: 78  ELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPL-NLSVLERTCAGSFSGVRKLVLNNS 136
           ELDL DN+++    +  +     +LE L++S N L N+  +++      + ++KL L N+
Sbjct: 124 ELDLYDNQIKKIENLEALT----ELEILDISFNLLRNIEGVDK-----LTRLKKLFLVNN 174

Query: 137 KAS----WETVHMI---------------LQELPDLEELFLCLNDYETV----SCPSICC 173
           K S       +H +               +  L +LE LFL  N    +    +  ++  
Sbjct: 175 KISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTV 234

Query: 174 HSLKLLHITD-NNLQDWTEIRKLGVMFPSLDTL--VLANNHLNAIEEPDDSLARL----- 225
            S++   +T    LQ+   +R+L +    ++ +  +  NN L  ++   + + ++     
Sbjct: 235 LSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISH 294

Query: 226 FPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVS 285
              L+   ++ + L+SW D+D+L     LE V L   PL +    + RRK+++A LPSV 
Sbjct: 295 LTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQK--DPQYRRKVMLA-LPSVR 351

Query: 286 KLNGSVV 292
           +++ + V
Sbjct: 352 QIDATFV 358


>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
          Length = 190

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 35/160 (21%), Positives = 78/160 (48%), Gaps = 10/160 (6%)

Query: 141 ETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFP 200
           E +   L  L + E+L L  N  E ++  +    +L++L +  NN+++   +  +G    
Sbjct: 38  EKMDASLSMLANCEKLSLSTNCIEKIANLN-GLKNLRILSLGRNNIKNLNGLEAVG---D 93

Query: 201 SLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLL 260
           +L+ L ++ N +  ++        +   L+ + +  + ++ W +  KL   P LE++  +
Sbjct: 94  TLEELWISYNFIEKLKG-----IHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFV 148

Query: 261 GIPLLQPYTTEER-RKLVIARLPSVSKLNGSVVTDGERED 299
           G PL + ++ E    +    R+P + KL+G+ V  G+ E+
Sbjct: 149 GNPLEEKHSAENNWIEEATKRVPKLKKLDGTPVIKGDEEE 188


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 74/296 (25%), Positives = 127/296 (42%), Gaps = 57/296 (19%)

Query: 53  LVLNSCGITCAGDEKEIAAFCA--HVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSN 110
           L L+ C +       +++  C   H+ +LDLS NK+ED       VS +P L  LN S N
Sbjct: 132 LTLSGCNLI------DVSILCGYVHLQKLDLSANKIED----LSCVSCMPYLLELNASQN 181

Query: 111 PLNLSVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLE------ELFLCLNDYE 164
            L       T   +F   + L     KA +   H  + E+ DL       +L L  N+ E
Sbjct: 182 NL-------TTFFNFKPPKNL----KKADFS--HNQISEICDLSAYHALTKLILDGNEIE 228

Query: 165 TVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLAR 224
            +S   + C++L  L + +N +     + KL +       L L+NN +  I   +D  A 
Sbjct: 229 EISGLEM-CNNLIHLSLANNKITTINGLNKLPIKI-----LCLSNNQIEMITGLEDLKA- 281

Query: 225 LFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKL-VIARLPS 283
               L+++ L           ++++S   LE   LL +  L+     E R++  I  LP 
Sbjct: 282 ----LQNLDLSH---------NQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPI 328

Query: 284 VSKLNGSVVTDGEREDSERFFIRYYVDVPQEEV---PFRYHELITKYGKLEPLAEV 336
           +  LN  ++ +  +E SE +F   ++ +   E+     +  E ++   K +P  EV
Sbjct: 329 LRVLN--LLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYDPPPEV 382


>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 31/160 (19%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNN 135
           +  L   DN+L       + +  VP L+FL+L+ NP     L+R   G F+ +       
Sbjct: 239 LESLSFYDNQLA--RVPRRALEQVPGLKFLDLNKNP-----LQRVGPGDFANM------- 284

Query: 136 SKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKL 195
                  +H+    L ++EEL + ++ +  V+ P      L  L IT+N    +   R  
Sbjct: 285 -------LHLKELGLNNMEEL-VSIDKFALVNLP-----ELTKLDITNNPRLSFIHPRAF 331

Query: 196 GVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLH 235
             + P ++TL+L NN L+A+ +         PNL+ + LH
Sbjct: 332 HHL-PQMETLMLNNNALSALHQ---QTVESLPNLQEVGLH 367


>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 31/160 (19%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNN 135
           +  L   DN+L       + +  VP L+FL+L+ NP     L+R   G F+ +       
Sbjct: 239 LESLSFYDNQLA--RVPRRALEQVPGLKFLDLNKNP-----LQRVGPGDFANM------- 284

Query: 136 SKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKL 195
                  +H+    L ++EEL + ++ +  V+ P      L  L IT+N    +   R  
Sbjct: 285 -------LHLKELGLNNMEEL-VSIDKFALVNLP-----ELTKLDITNNPRLSFIHPRAF 331

Query: 196 GVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLH 235
             + P ++TL+L NN L+A+ +         PNL+ + LH
Sbjct: 332 HHL-PQMETLMLNNNALSALHQ---QTVESLPNLQEVGLH 367


>gi|21389431 leucine rich repeat containing 39 [Homo sapiens]
          Length = 335

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 53/201 (26%), Positives = 87/201 (43%), Gaps = 16/201 (7%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLV-LN 134
           + EL LS NK++    V K +SN   LE L L+ N     + +       S + KL  L+
Sbjct: 131 LQELILSYNKIKT---VPKELSNCASLEKLELAVNRDICDLPQE-----LSNLLKLTHLD 182

Query: 135 NSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRK 194
            S   + T+ + +  +P LE L +  N  E +        +L  L +  N +   T + +
Sbjct: 183 LSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEI---TCLPQ 239

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPKL 254
                 +L TLVL+NN L  I    + +A    NLR ++   + L+    +       + 
Sbjct: 240 TISNMKNLGTLVLSNNKLQDIPVCMEEMA----NLRFVNFRDNPLKLKVSLPPSEGTDEE 295

Query: 255 EEVRLLGIPLLQPYTTEERRK 275
           EE  L G+  +  Y  E RR+
Sbjct: 296 EERELFGLQFMHTYIQESRRR 316



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 50/208 (24%), Positives = 90/208 (43%), Gaps = 43/208 (20%)

Query: 66  EKEIAAFCAHVSELDLSDNKLED--WHEVSKIVSNVPQLEFLNLSSNPLNLSVLER---- 119
           EKE       + E  +S  KL +    E  +++  + + E+  L S+ L L+ L+     
Sbjct: 32  EKEFQHKLVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLH 91

Query: 120 --------TCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETV----- 166
                      G F  +  +VL+ S+ +   +   +  L  L+EL L  N  +TV     
Sbjct: 92  RTGLLKIPEFIGRFQNL--IVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELS 149

Query: 167 SCPS-----------IC------CHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLAN 209
           +C S           IC       + LKL H+ D ++ D+T I    +  P+L+ L + +
Sbjct: 150 NCASLEKLELAVNRDICDLPQELSNLLKLTHL-DLSMNDFTTIPLAVLNMPALEWLDMGS 208

Query: 210 NHLNAIEEPDDSLARLFPNLRSISLHKS 237
           N L   E+  D++ R+  NL ++ L ++
Sbjct: 209 NKL---EQLPDTIERM-QNLHTLWLQRN 232


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 55/211 (26%), Positives = 91/211 (43%), Gaps = 36/211 (17%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNN 135
           + EL LS NK+   H  +K    VP L  L+LS N L     E+     F G+RKL++ +
Sbjct: 111 LKELILSSNKITYLH--NKTFHPVPNLRNLDLSYNKLQTLQSEQ-----FKGLRKLIILH 163

Query: 136 SKA-SWETVHM-ILQELPDLEELFLCLNDYETVSCPSIC-CHSLKLLHITDNNLQ----- 187
            ++ S +TV + + Q+  +L+ L L  N   ++S  +      LK LH+  N        
Sbjct: 164 LRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFA 223

Query: 188 -------------DWTEIRKLGV----MFPSLDTLVLANNHLNAIEEPDDSLARLFPNLR 230
                         W  IR +       + SL  L L+ N +  IE       +  PNL+
Sbjct: 224 HFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE---PGTFKCLPNLQ 280

Query: 231 SISLHKSGLQSWEDIDKLNSFPKLEEVRLLG 261
            ++L  + L +    + +N++  L  + L G
Sbjct: 281 KLNLDSNKLTNISQ-ETVNAWISLISITLSG 310


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 55/211 (26%), Positives = 91/211 (43%), Gaps = 36/211 (17%)

Query: 76  VSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNN 135
           + EL LS NK+   H  +K    VP L  L+LS N L     E+     F G+RKL++ +
Sbjct: 111 LKELILSSNKITYLH--NKTFHPVPNLRNLDLSYNKLQTLQSEQ-----FKGLRKLIILH 163

Query: 136 SKA-SWETVHM-ILQELPDLEELFLCLNDYETVSCPSIC-CHSLKLLHITDNNLQ----- 187
            ++ S +TV + + Q+  +L+ L L  N   ++S  +      LK LH+  N        
Sbjct: 164 LRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFA 223

Query: 188 -------------DWTEIRKLGV----MFPSLDTLVLANNHLNAIEEPDDSLARLFPNLR 230
                         W  IR +       + SL  L L+ N +  IE       +  PNL+
Sbjct: 224 HFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIE---PGTFKCLPNLQ 280

Query: 231 SISLHKSGLQSWEDIDKLNSFPKLEEVRLLG 261
            ++L  + L +    + +N++  L  + L G
Sbjct: 281 KLNLDSNKLTNISQ-ETVNAWISLISITLSG 310


>gi|4503743 flightless I homolog [Homo sapiens]
          Length = 1269

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 8/109 (7%)

Query: 79  LDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNNSKA 138
           L+LS N++    E+S  +     +E LNLS N L  S+    C    S ++KL LN++K 
Sbjct: 251 LNLSSNQIT---ELSLCIDQWVHVETLNLSRNQLT-SLPSAIC--KLSKLKKLYLNSNKL 304

Query: 139 SWETVHMILQELPDLEELFLCLNDYETVSCPSIC-CHSLKLLHITDNNL 186
            ++ +   + +L +LEE     N+ E V   S+C C  L+ L +  N+L
Sbjct: 305 DFDGLPSGIGKLTNLEEFMAANNNLELVP-ESLCRCPKLRKLVLNKNHL 352


>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
          Length = 708

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 50/214 (23%), Positives = 89/214 (41%), Gaps = 45/214 (21%)

Query: 44  KDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLE 103
           K  +NL S+++    GI              ++  +   DN+L     V+  +  V  L+
Sbjct: 209 KPLINLRSLVI---AGINLTEIPDNALVGLENLESISFYDNRLIKVPHVA--LQKVVNLK 263

Query: 104 FLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNNSKASWETVHMILQELPDLEELFLCL 160
           FL+L+ NP+N     R   G FS    +++L +NN         + +  LPDL ++    
Sbjct: 264 FLDLNKNPIN-----RIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKI---- 314

Query: 161 NDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDD 220
              E  + P       +L +I  N               P L++L+L +N L+A+     
Sbjct: 315 ---EATNNP-------RLSYIHPNAF----------FRLPKLESLMLNSNALSALYH--- 351

Query: 221 SLARLFPNLRSISLHKSGLQ-----SWEDIDKLN 249
                 PNL+ IS+H + ++      W +++K N
Sbjct: 352 GTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTN 385


>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
          Length = 708

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 50/214 (23%), Positives = 89/214 (41%), Gaps = 45/214 (21%)

Query: 44  KDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLE 103
           K  +NL S+++    GI              ++  +   DN+L     V+  +  V  L+
Sbjct: 209 KPLINLRSLVI---AGINLTEIPDNALVGLENLESISFYDNRLIKVPHVA--LQKVVNLK 263

Query: 104 FLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNNSKASWETVHMILQELPDLEELFLCL 160
           FL+L+ NP+N     R   G FS    +++L +NN         + +  LPDL ++    
Sbjct: 264 FLDLNKNPIN-----RIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKI---- 314

Query: 161 NDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDD 220
              E  + P       +L +I  N               P L++L+L +N L+A+     
Sbjct: 315 ---EATNNP-------RLSYIHPNAF----------FRLPKLESLMLNSNALSALYH--- 351

Query: 221 SLARLFPNLRSISLHKSGLQ-----SWEDIDKLN 249
                 PNL+ IS+H + ++      W +++K N
Sbjct: 352 GTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTN 385


>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
          Length = 708

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 50/214 (23%), Positives = 89/214 (41%), Gaps = 45/214 (21%)

Query: 44  KDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLE 103
           K  +NL S+++    GI              ++  +   DN+L     V+  +  V  L+
Sbjct: 209 KPLINLRSLVI---AGINLTEIPDNALVGLENLESISFYDNRLIKVPHVA--LQKVVNLK 263

Query: 104 FLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNNSKASWETVHMILQELPDLEELFLCL 160
           FL+L+ NP+N     R   G FS    +++L +NN         + +  LPDL ++    
Sbjct: 264 FLDLNKNPIN-----RIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKI---- 314

Query: 161 NDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDD 220
              E  + P       +L +I  N               P L++L+L +N L+A+     
Sbjct: 315 ---EATNNP-------RLSYIHPNAF----------FRLPKLESLMLNSNALSALYH--- 351

Query: 221 SLARLFPNLRSISLHKSGLQ-----SWEDIDKLN 249
                 PNL+ IS+H + ++      W +++K N
Sbjct: 352 GTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTN 385


>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
          Length = 466

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 12/145 (8%)

Query: 153 LEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHL 212
           LEEL L   + E +      C  LK+L++ +N +     + KL      L+ L LA N++
Sbjct: 23  LEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKL----KKLEYLNLALNNI 78

Query: 213 NAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEE 272
             IE  +         L  + L  + +     I  L     L+E+ L+G P     + + 
Sbjct: 79  EKIENLEGC-----EELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCA---SFDH 130

Query: 273 RRKLVIARLPSVSKLNGSVVTDGER 297
            R+ V+A LP +  L+G  +   ER
Sbjct: 131 YREFVVATLPQLKWLDGKEIEPSER 155


>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
           sapiens]
          Length = 255

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 191 EIRKLG--VMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKL 248
           EIRKL    +   L TL++ NN +  I E    L +  P L  + L  + L    D+D L
Sbjct: 53  EIRKLDGFPLLRRLKTLLVNNNRICRIGE---GLDQALPCLTELILTNNSLVELGDLDPL 109

Query: 249 NSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDSERFF 304
            S   L  + +L  P+      +  R  VI ++P V  L+   V   ER+++E+ F
Sbjct: 110 ASLKSLTYLSILRNPVTNK---KHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMF 162


>gi|20143971 toll-like receptor 6 [Homo sapiens]
          Length = 796

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 43/175 (24%), Positives = 80/175 (45%), Gaps = 14/175 (8%)

Query: 79  LDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNNSKA 138
           L L  N L+D  +V  +  ++P LE L++S N L     +  C    + V  +V+ N  +
Sbjct: 382 LILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESGRHKENC----TWVESIVVLNLSS 437

Query: 139 SWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVM 198
           +  T  +     P ++ L L  N  ++V    +   +L+ L++  N+L   T++   G  
Sbjct: 438 NMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSL---TDLPGCG-S 493

Query: 199 FPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPK 253
           F SL  L++ +   N++  P     +    +RSI   K+G   ++   +L  F K
Sbjct: 494 FSSLSVLIIDH---NSVSHPSADFFQSCQKMRSI---KAGDNPFQCTCELREFVK 542


>gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]
          Length = 198

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 17/135 (12%)

Query: 177 KLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHK 236
           K L ++ N+  +   +  L   F SL+ L+L NN L      DD +    P L +++L+K
Sbjct: 3   KYLSLSGNHSSNKRSLEGLSA-FRSLEELILDNNQLG-----DDLVLPGLPRLHTLTLNK 56

Query: 237 SGLQSWEDI-DKLNSF-PKLEEVRLLGI-----PLLQPYTTEERRK----LVIARLPSVS 285
           + +   E++ D L    P LE + LLG       L+     EE  K     V+ +LP++ 
Sbjct: 57  NRITDLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLK 116

Query: 286 KLNGSVVTDGEREDS 300
            L+   VT  ERE++
Sbjct: 117 FLDAQKVTRQEREEA 131


>gi|15487670 nuclear RNA export factor 1 isoform 1 [Homo sapiens]
          Length = 619

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 3/91 (3%)

Query: 200 PSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRL 259
           P L +L L+NN L  +++   S+ +  PNL+ ++L  + L+S  ++DK+    KLEE+ L
Sbjct: 265 PELLSLNLSNNRLYRLDDMS-SIVQKAPNLKILNLSGNELKSERELDKIKGL-KLEELWL 322

Query: 260 LGIPLLQPYTTEERR-KLVIARLPSVSKLNG 289
            G  L   +  +      +  R P + +L+G
Sbjct: 323 DGNSLCDTFRDQSTYISAIRERFPKLLRLDG 353



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 48  NLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNL 107
           N+  VL   SC    A   + I      +  L+LS+N+L    ++S IV   P L+ LNL
Sbjct: 242 NIDVVLNRRSC---MAATLRIIEENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNL 298

Query: 108 SSNPL 112
           S N L
Sbjct: 299 SGNEL 303


>gi|41350337 toll-like receptor 1 [Homo sapiens]
          Length = 786

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 43/185 (23%), Positives = 91/185 (49%), Gaps = 19/185 (10%)

Query: 73  CAHVSELD---LSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVR 129
           C H++EL+   L  N+L++  +++++ + +  L+ L++S N ++    +  C+ + S   
Sbjct: 368 CGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCSWTKS--- 424

Query: 130 KLVLN-NSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQD 188
            L LN +S    +T+   L   P ++ L L  N  +++    +   +L+ L++  N+L  
Sbjct: 425 LLSLNMSSNILTDTIFRCLP--PRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL-- 480

Query: 189 WTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKL 248
            T++   G  F SL  L++ +   N++  P     +    +RSI   K+G   ++   +L
Sbjct: 481 -TDLPGCG-SFSSLSVLIIDH---NSVSHPSADFFQSCQKMRSI---KAGDNPFQCTCEL 532

Query: 249 NSFPK 253
             F K
Sbjct: 533 GEFVK 537


>gi|42822866 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


>gi|42822864 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


>gi|42822868 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


>gi|42822870 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


>gi|42822874 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


>gi|42794608 ribonuclease/angiogenin inhibitor [Homo sapiens]
          Length = 461

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 92  VSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSG---VRKLVLNN---SKASWETVHM 145
           +S  +  +P L+ L+LS N L  + L+  C G       + KL L     S AS E +  
Sbjct: 105 LSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLAS 164

Query: 146 ILQELPDLEELFLCLNDYETVSCPSIC---------CHSLKL--LHITDNNLQDWTEIRK 194
           +L+  PD +EL +  ND        +C           +LKL    +T +N +D   +  
Sbjct: 165 VLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD---LCG 221

Query: 195 LGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWE 243
           +     SL  L L +N L      D  +A L P L   S     L  WE
Sbjct: 222 IVASKASLRELALGSNKLG-----DVGMAELCPGLLHPSSRLRTLWIWE 265


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,920,884
Number of Sequences: 37866
Number of extensions: 787314
Number of successful extensions: 2417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 2292
Number of HSP's gapped (non-prelim): 198
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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