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Search of human proteins with 194018492
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 885 0.0
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 355 6e-98
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ... 351 6e-97
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 349 2e-96
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 349 3e-96
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 333 1e-91
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 320 1e-87
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 208 7e-54
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 208 7e-54
gi|223942069 enterokinase precursor [Homo sapiens] 195 6e-50
gi|33695155 hepsin [Homo sapiens] 195 8e-50
gi|4504481 hepsin [Homo sapiens] 195 8e-50
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 195 8e-50
gi|11415040 matriptase [Homo sapiens] 193 2e-49
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 188 7e-48
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 187 2e-47
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 186 3e-47
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 186 5e-47
gi|148613878 acrosin precursor [Homo sapiens] 185 8e-47
gi|4503627 coagulation factor XI precursor [Homo sapiens] 184 2e-46
gi|117956391 protease, serine, 33 [Homo sapiens] 181 9e-46
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 181 1e-45
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 180 2e-45
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 179 3e-45
gi|21614531 testisin isoform 2 [Homo sapiens] 177 2e-44
gi|13994276 marapsin [Homo sapiens] 175 6e-44
gi|5803197 testisin isoform 1 [Homo sapiens] 175 6e-44
gi|110815798 ovochymase 1 [Homo sapiens] 173 2e-43
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 173 3e-43
gi|11545839 protease, serine, 22 [Homo sapiens] 173 3e-43
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 885 bits (2287), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY 60
MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY
Sbjct: 1 MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY 60
Query: 61 YLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDE 120
YLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDE
Sbjct: 61 YLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDE 120
Query: 121 QGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRN 180
QGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRN
Sbjct: 121 QGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRN 180
Query: 181 LLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISN 240
LLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISN
Sbjct: 181 LLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISN 240
Query: 241 TWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLS 300
TWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLS
Sbjct: 241 TWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLS 300
Query: 301 TGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNR 360
TGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNR
Sbjct: 301 TGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNR 360
Query: 361 KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPG 420
KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPG
Sbjct: 361 KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPG 420
Query: 421 VYTRVTKYRDWIASKTGM 438
VYTRVTKYRDWIASKTGM
Sbjct: 421 VYTRVTKYRDWIASKTGM 438
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 355 bits (910), Expect = 6e-98
Identities = 188/439 (42%), Positives = 268/439 (61%), Gaps = 22/439 (5%)
Query: 1 MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY 60
MMY V F R + W L + +L +VA+ IG++ HF+V D K Y
Sbjct: 1 MMYRTVGFGTRS-------RNLKPWMIAVLIVLSLTVVAV---TIGLLVHFLVFDQKKEY 50
Query: 61 YLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDE 120
Y SFK+ + + N+G ++ + + E ++ IF S+ +IK+ V++L+P+E
Sbjct: 51 YHGSFKILDPQINNNFGQSNTYQLKDLRETTENLVDEIFIDSAWKKNYIKNQVVRLTPEE 110
Query: 121 QGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRN 180
GV + ++++F++PST+ +KKI+ L Q ++ + +L IN S ++ + S
Sbjct: 111 DGVKVDVIMVFQFPSTEQRAVREKKIQSILNQKIRNLR-ALPINASSVQVNAMSSSTGEL 169
Query: 181 LLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISN 240
+ + CG R+ N+ RI G A + WPWQASLQ + HQCGA+LISN
Sbjct: 170 TVQASCGKRVVPLNV--------NRIASG-VIAPKAAWPWQASLQY-DNIHQCGATLISN 219
Query: 241 TWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLS 300
TWL+TAAHCF K K+P QW +FG I PP +KRNVR+ I+HE Y E DIA+VQ+S
Sbjct: 220 TWLVTAAHCFQKYKNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVS 279
Query: 301 TGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNR 360
+ V FS+ ++++CLP++S P +V +TGFG++ G QN LR+ARV+ IS DVC +
Sbjct: 280 SRVTFSDDIRQICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQ 339
Query: 361 KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLV-YDNHDIWYIVGIVSWGQSCALPKKP 419
VY I PGM CAG+MEG DAC+GDSGGPLV D D WY++GIVSWG +C KP
Sbjct: 340 PQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKP 399
Query: 420 GVYTRVTKYRDWIASKTGM 438
GVYT+VT YR+WIASKTG+
Sbjct: 400 GVYTQVTYYRNWIASKTGI 418
>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
sapiens]
Length = 421
Score = 351 bits (901), Expect = 6e-97
Identities = 189/442 (42%), Positives = 270/442 (61%), Gaps = 25/442 (5%)
Query: 1 MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY 60
MMY V F R + W L + +L +VA+ IG++ HF+V D K Y
Sbjct: 1 MMYRTVGFGTRS-------RNLKPWMIAVLIVLSLTVVAV---TIGLLVHFLVFDQKKEY 50
Query: 61 YLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSR---IFRHSSVGGRFIKSHVIKLS 117
Y SFK+ + + N+G ++ + + E ++S+ IF S+ +IK+ V++L+
Sbjct: 51 YHGSFKILDPQINNNFGQSNTYQLKDLRETTENLVSQVDEIFIDSAWKKNYIKNQVVRLT 110
Query: 118 PDEQGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKK 177
P+E GV + ++++F++PST+ +KKI+ L Q ++ + +L IN S ++ + S
Sbjct: 111 PEEDGVKVDVIMVFQFPSTEQRAVREKKIQSILNQKIRNLR-ALPINASSVQVNAMSSST 169
Query: 178 MRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASL 237
+ + CG R+ N+ RI G A + WPWQASLQ + HQCGA+L
Sbjct: 170 GELTVQASCGKRVVPLNV--------NRIASG-VIAPKAAWPWQASLQY-DNIHQCGATL 219
Query: 238 ISNTWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALV 297
ISNTWL+TAAHCF K K+P QW +FG I PP +KRNVR+ I+HE Y E DIA+V
Sbjct: 220 ISNTWLVTAAHCFQKYKNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVV 279
Query: 298 QLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDV 357
Q+S+ V FS+ ++++CLP++S P +V +TGFG++ G QN LR+ARV+ IS DV
Sbjct: 280 QVSSRVTFSDDIRQICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDV 339
Query: 358 CNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLV-YDNHDIWYIVGIVSWGQSCALP 416
C + VY I PGM CAG+MEG DAC+GDSGGPLV D D WY++GIVSWG +C
Sbjct: 340 CKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQK 399
Query: 417 KKPGVYTRVTKYRDWIASKTGM 438
KPGVYT+VT YR+WIASKTG+
Sbjct: 400 DKPGVYTQVTYYRNWIASKTGI 421
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 349 bits (896), Expect = 2e-96
Identities = 184/421 (43%), Positives = 256/421 (60%), Gaps = 10/421 (2%)
Query: 20 RKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY-YLASFKVTNIKYKENYGI 78
RK+ W+ + L + ++ + IG+ H+V + K Y Y ++ T K +G
Sbjct: 11 RKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGR 70
Query: 79 RSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDS 138
+S F E S ++E M+ F S + F+KS VIK S + GV ++LI R+ ST+
Sbjct: 71 EASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTED 130
Query: 139 AEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLP 198
E + K ++ L++ L+ ++ S ++ I+ + + LN CG R + +
Sbjct: 131 PETVDKIVQLVLHEKLQDAVGPPKVDPQSVKIKKINKTETDSYLNHCCGTRRSKT----- 185
Query: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQ 258
+ RIV G E EGEWPWQASLQ GS H+CGA+LI+ TWL++AAHCF K+P +
Sbjct: 186 -LGQSLRIVGGTEVE-EGEWPWQASLQWDGS-HRCGATLINATWLVSAAHCFTTYKNPAR 242
Query: 259 WIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318
W A+FG TI P +KR +R+II+HE Y +++ DI+L +LS+ V ++N V RVCLPD+S
Sbjct: 243 WTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDAS 302
Query: 319 IKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFM 378
+ P +FVTGFG++ +DG QN LRQA+V I CN Y+ ITP MLCAG +
Sbjct: 303 YEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSL 362
Query: 379 EGKIDACKGDSGGPLV-YDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437
EGK DAC+GDSGGPLV D DIWY+ GIVSWG CA P KPGVYTRVT RDWI SKTG
Sbjct: 363 EGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422
Query: 438 M 438
+
Sbjct: 423 I 423
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 349 bits (895), Expect = 3e-96
Identities = 184/421 (43%), Positives = 256/421 (60%), Gaps = 10/421 (2%)
Query: 20 RKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFY-YLASFKVTNIKYKENYGI 78
RK+ W+ + L + ++ + IG+ H+V + K Y Y ++ T K +G
Sbjct: 11 RKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGR 70
Query: 79 RSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDS 138
+S F E S ++E M+ F S + F+KS VIK S + GV ++LI R+ ST+
Sbjct: 71 EASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTED 130
Query: 139 AEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLP 198
E + K ++ L++ L+ ++ S ++ I+ + + LN CG R + +
Sbjct: 131 PETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKT----- 185
Query: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQ 258
+ RIV G E EGEWPWQASLQ GS H+CGA+LI+ TWL++AAHCF K+P +
Sbjct: 186 -LGQSLRIVGGTEVE-EGEWPWQASLQWDGS-HRCGATLINATWLVSAAHCFTTYKNPAR 242
Query: 259 WIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318
W A+FG TI P +KR +R+II+HE Y +++ DI+L +LS+ V ++N V RVCLPD+S
Sbjct: 243 WTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDAS 302
Query: 319 IKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFM 378
+ P +FVTGFG++ +DG QN LRQA+V I CN Y+ ITP MLCAG +
Sbjct: 303 YEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSL 362
Query: 379 EGKIDACKGDSGGPLV-YDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437
EGK DAC+GDSGGPLV D DIWY+ GIVSWG CA P KPGVYTRVT RDWI SKTG
Sbjct: 363 EGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422
Query: 438 M 438
+
Sbjct: 423 I 423
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 333 bits (855), Expect = 1e-91
Identities = 175/417 (41%), Positives = 254/417 (60%), Gaps = 11/417 (2%)
Query: 23 QFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGIRSSR 82
+F + + +A V I+ + I ++ +F+ D KS++Y +SF++ N++Y +++
Sbjct: 12 RFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQ 71
Query: 83 EFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDSAEQI 142
E+ S +IE ++++ F+ S++ +FI++HV KL D GV +V+ F++ ++ +
Sbjct: 72 EYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASM 131
Query: 143 KKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSS 202
K +IE L Q L +L IN PS +T + + N L + CG P + S
Sbjct: 132 KSRIESVLRQMLNNSG-NLEIN-PSTEITSLTDQAAANWLINECGAG------PDLITLS 183
Query: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIAT 262
QRI+ G E A EG WPWQ SL+L + H CG SLI+N W+LTAAHCF N +P WIAT
Sbjct: 184 EQRILGGTE-AEEGSWPWQVSLRL-NNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIAT 241
Query: 263 FGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLP 322
G + T P ++ VR I++H NY T+ENDIALV+L V F+ + VCLP ++ +P
Sbjct: 242 SGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301
Query: 323 PKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKI 382
P ++ +VTG+G+ G LRQ +V IS DVCN Y+G I GMLCAG +G +
Sbjct: 302 PGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGV 361
Query: 383 DACKGDSGGPLVY-DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTGM 438
DAC+GDSGGPLV D+ +W+IVGIVSWG C LP KPGVYTRVT Y DWI +TG+
Sbjct: 362 DACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 320 bits (821), Expect = 1e-87
Identities = 166/421 (39%), Positives = 247/421 (58%), Gaps = 14/421 (3%)
Query: 19 QRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGI 78
QR W ++ L + AI+G+ IG++ HF+ + K++YY F ++ + Y +N
Sbjct: 9 QRSWPLWTTI---FIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGVTYNDNCEN 64
Query: 79 RSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDS 138
+S+ S IE M F++SS+ ++KS VIKL P+ G ++ + L F++P +
Sbjct: 65 AASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEG 124
Query: 139 AEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLP 198
++ KI+ L+Q LK S S +L I L N+ CG ++ +S +
Sbjct: 125 VS-MRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSII--- 180
Query: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQ 258
+ +IV G+ +++EG WPWQAS+Q G H CGASLIS+ WLL+AAHCF K +
Sbjct: 181 ---TGNKIVNGK-SSLEGAWPWQASMQWKGR-HYCGASLISSRWLLSAAHCFAKKNNSKD 235
Query: 259 WIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318
W FG + P + R V+ II HENY +DIALVQL+ V F+ ++++CLP++
Sbjct: 236 WTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAK 295
Query: 319 IKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFM 378
+KL +V VTG+G++ +G L++ ++ I +CN Y G +T MLCAGFM
Sbjct: 296 MKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFM 355
Query: 379 EGKIDACKGDSGGPLVY-DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437
G+ DAC+ DSGGPL Y D+ +IW++VGIVSWG C KPGVYTRVT YR+WI SKTG
Sbjct: 356 SGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTG 415
Query: 438 M 438
+
Sbjct: 416 L 416
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 208 bits (530), Expect = 7e-54
Identities = 110/286 (38%), Positives = 161/286 (56%), Gaps = 14/286 (4%)
Query: 151 YQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGR 210
+ L T ++ I K + SK + +L CG+ + SS RIV G
Sbjct: 246 FMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQ--------SRIVGG- 296
Query: 211 ETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKN-KDPTQWIATFGA---T 266
E+A+ G WPWQ SL + + H CG S+I+ W++TAAHC K +P W A G +
Sbjct: 297 ESALPGAWPWQVSLH-VQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQS 355
Query: 267 ITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTS 326
V K+I H NY +T NDIAL++L + F+++V+ VCLP+ + L P+
Sbjct: 356 FMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQL 415
Query: 327 VFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACK 386
+++G+G+ + G L A+V I T CN + VYD LITP M+CAGF++G +D+C+
Sbjct: 416 CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQ 475
Query: 387 GDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
GDSGGPLV ++IW+++G SWG CA +PGVY V + DWI
Sbjct: 476 GDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 208 bits (530), Expect = 7e-54
Identities = 110/286 (38%), Positives = 161/286 (56%), Gaps = 14/286 (4%)
Query: 151 YQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGR 210
+ L T ++ I K + SK + +L CG+ + SS RIV G
Sbjct: 209 FMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQ--------SRIVGG- 259
Query: 211 ETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKN-KDPTQWIATFGA---T 266
E+A+ G WPWQ SL + + H CG S+I+ W++TAAHC K +P W A G +
Sbjct: 260 ESALPGAWPWQVSLH-VQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQS 318
Query: 267 ITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTS 326
V K+I H NY +T NDIAL++L + F+++V+ VCLP+ + L P+
Sbjct: 319 FMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQL 378
Query: 327 VFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACK 386
+++G+G+ + G L A+V I T CN + VYD LITP M+CAGF++G +D+C+
Sbjct: 379 CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQ 438
Query: 387 GDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
GDSGGPLV ++IW+++G SWG CA +PGVY V + DWI
Sbjct: 439 GDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 195 bits (496), Expect = 6e-50
Identities = 100/271 (36%), Positives = 162/271 (59%), Gaps = 11/271 (4%)
Query: 170 LTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGS 229
LTP +L+ +C + S L A T +IV G A EG WPW L G
Sbjct: 751 LTPSQQCLQDSLIRLQCNHK--SCGKKLAAQDITPKIVGG-SNAKEGAWPWVVGLYY-GG 806
Query: 230 GHQCGASLISNTWLLTAAHCFW-KNKDPTQWIATFGATI-----TPPAVKRNVRKIILHE 283
CGASL+S+ WL++AAHC + +N +P++W A G + +P V R + +I+++
Sbjct: 807 RLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINP 866
Query: 284 NYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQN 343
+Y+R +NDIA++ L V +++ +Q +CLP+ + PP + + G+G++V G N
Sbjct: 867 HYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTAN 926
Query: 344 TLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYI 403
L++A V +S + C ++ + + IT M+CAG+ EG ID+C+GDSGGPL+ ++ W++
Sbjct: 927 ILQEADVPLLSNERCQQQ-MPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFL 985
Query: 404 VGIVSWGQSCALPKKPGVYTRVTKYRDWIAS 434
G+ S+G CALP +PGVY RV+++ +WI S
Sbjct: 986 AGVTSFGYKCALPNRPGVYARVSRFTEWIQS 1016
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 195 bits (495), Expect = 8e-50
Identities = 108/241 (44%), Positives = 145/241 (60%), Gaps = 15/241 (6%)
Query: 205 RIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCF-WKNKDPTQWIATF 263
RIV GR+T++ G WPWQ SL+ G+ H CG SL+S W+LTAAHCF +N+ ++W
Sbjct: 162 RIVGGRDTSL-GRWPWQVSLRYDGA-HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 219
Query: 264 GATI--TPPAVKRNVRKIILHENY------HRETNENDIALVQLSTGVEFSNIVQRVCLP 315
GA +P ++ V+ ++ H Y + E N NDIALV LS+ + + +Q VCLP
Sbjct: 220 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 279
Query: 316 DSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCA 375
+ L VTG+G+ G L++ARV IS DVCN D Y I P M CA
Sbjct: 280 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 339
Query: 376 GFMEGKIDACKGDSGGPLVYDNH----DIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
G+ EG IDAC+GDSGGP V ++ W + GIVSWG CAL +KPGVYT+V+ +R+W
Sbjct: 340 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREW 399
Query: 432 I 432
I
Sbjct: 400 I 400
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 195 bits (495), Expect = 8e-50
Identities = 108/241 (44%), Positives = 145/241 (60%), Gaps = 15/241 (6%)
Query: 205 RIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCF-WKNKDPTQWIATF 263
RIV GR+T++ G WPWQ SL+ G+ H CG SL+S W+LTAAHCF +N+ ++W
Sbjct: 162 RIVGGRDTSL-GRWPWQVSLRYDGA-HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 219
Query: 264 GATI--TPPAVKRNVRKIILHENY------HRETNENDIALVQLSTGVEFSNIVQRVCLP 315
GA +P ++ V+ ++ H Y + E N NDIALV LS+ + + +Q VCLP
Sbjct: 220 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 279
Query: 316 DSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCA 375
+ L VTG+G+ G L++ARV IS DVCN D Y I P M CA
Sbjct: 280 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 339
Query: 376 GFMEGKIDACKGDSGGPLVYDNH----DIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
G+ EG IDAC+GDSGGP V ++ W + GIVSWG CAL +KPGVYT+V+ +R+W
Sbjct: 340 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREW 399
Query: 432 I 432
I
Sbjct: 400 I 400
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 195 bits (495), Expect = 8e-50
Identities = 100/233 (42%), Positives = 138/233 (59%), Gaps = 5/233 (2%)
Query: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIAT 262
+ RIV G + + +WPWQASLQ G H CG S+I+ W++TAAHC + P W
Sbjct: 214 SSRIVGGNMSLLS-QWPWQASLQFQGY-HLCGGSVITPLWIITAAHCVYDLYLPKSWTIQ 271
Query: 263 FG--ATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIK 320
G + + PA V KI+ H Y + NDIAL++L+ + F+ ++Q VCLP+S
Sbjct: 272 VGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEEN 331
Query: 321 LPPKTSVFVTGFGSIVDD-GPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFME 379
P + +G+G+ D G L A V IS +CN +DVY G+I+P MLCAG++
Sbjct: 332 FPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLT 391
Query: 380 GKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
G +D+C+GDSGGPLV +W +VG S+G CA KPGVYTRVT + DWI
Sbjct: 392 GGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 193 bits (491), Expect = 2e-49
Identities = 106/264 (40%), Positives = 150/264 (56%), Gaps = 23/264 (8%)
Query: 186 CGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLT 245
CG+R S + Q V G A EGEWPWQ SL +G GH CGASLIS WL++
Sbjct: 604 CGLR----------SFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVS 653
Query: 246 AAHCF-----WKNKDPTQWIATFG-----ATITPPAVKRNVRKIILHENYHRETNENDIA 295
AAHC+ ++ DPTQW A G P +R +++II H ++ T + DIA
Sbjct: 654 AAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIA 713
Query: 296 LVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETIST 355
L++L E+S++V+ +CLPD+S P +++VTG+G G L++ + I+
Sbjct: 714 LLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQ 773
Query: 356 DVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHD-IWYIVGIVSWGQSCA 414
C +++ ITP M+C GF+ G +D+C+GDSGGPL D + G+VSWG CA
Sbjct: 774 TTC--ENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCA 831
Query: 415 LPKKPGVYTRVTKYRDWIASKTGM 438
KPGVYTR+ +RDWI TG+
Sbjct: 832 QRNKPGVYTRLPLFRDWIKENTGV 855
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 188 bits (478), Expect = 7e-48
Identities = 103/252 (40%), Positives = 144/252 (57%), Gaps = 9/252 (3%)
Query: 191 TSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQ--LIGSGHQCGASLISNTWLLTAAH 248
T N +ST RIV G ++ GEWPWQ SLQ L H CG SLI + W+LTAAH
Sbjct: 377 TGDNSVCTTKTST-RIVGGTNSSW-GEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAH 434
Query: 249 CFWKNKDPTQWIATFG----ATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVE 304
CF W G + IT +++II+H+NY +DIAL++L +
Sbjct: 435 CFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLN 494
Query: 305 FSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVY 364
++ + +CLP T+ +VTG+G + G IQN L++ + ++ + C +K
Sbjct: 495 YTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQ 553
Query: 365 DGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTR 424
D IT M+CAG+ EG DACKGDSGGPLV ++ +W +VGI SWG+ CA ++PGVYT+
Sbjct: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613
Query: 425 VTKYRDWIASKT 436
V +Y DWI KT
Sbjct: 614 VAEYMDWILEKT 625
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 187 bits (475), Expect = 2e-47
Identities = 107/286 (37%), Positives = 155/286 (54%), Gaps = 20/286 (6%)
Query: 164 NKPSFR---LTPIDSKKMRNLLNSRCGIRMTSSNMPLPASS-------------STQRIV 207
+KP+FR + P + + + +RM +S+ P + S T R+V
Sbjct: 147 SKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVV 206
Query: 208 QGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGATI 267
G E +++ WPWQ S+Q H CG S++ W+LTAAHCF K+ D W G+
Sbjct: 207 GGEEASVDS-WPWQVSIQY-DKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDK 264
Query: 268 TPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSV 327
V KII+ E +NDIAL++L + FS V+ +CLP +L P T +
Sbjct: 265 LGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPL 324
Query: 328 FVTGFGSIVDDG-PIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACK 386
++ G+G +G + + L QA V+ I + CN D Y G +T M+CAG EG +D C+
Sbjct: 325 WIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQ 384
Query: 387 GDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
GDSGGPL+Y + D W++VGIVSWG C P PGVYT+V+ Y +WI
Sbjct: 385 GDSGGPLMYQS-DQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 186 bits (473), Expect = 3e-47
Identities = 98/234 (41%), Positives = 136/234 (58%), Gaps = 4/234 (1%)
Query: 200 SSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQW 259
S T R+V G E +++ WPWQ S+Q H CG S++ W+LTAAHCF K+ D W
Sbjct: 194 SLKTPRVVGGEEASVDS-WPWQVSIQY-DKQHVCGGSILDPHWVLTAAHCFRKHTDVFNW 251
Query: 260 IATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSI 319
G+ V KII+ E +NDIAL++L + FS V+ +CLP
Sbjct: 252 KVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 311
Query: 320 KLPPKTSVFVTGFGSIVDDG-PIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFM 378
+L P T +++ G+G +G + + L QA V+ I + CN D Y G +T M+CAG
Sbjct: 312 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIP 371
Query: 379 EGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
EG +D C+GDSGGPL+Y + D W++VGIVSWG C P PGVYT+V+ Y +WI
Sbjct: 372 EGGVDTCQGDSGGPLMYQS-DQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 186 bits (471), Expect = 5e-47
Identities = 99/245 (40%), Positives = 153/245 (62%), Gaps = 10/245 (4%)
Query: 198 PASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPT 257
PA RIV G E A GE+PWQASL+ H CGA++I+ WL++AAHCF + +DPT
Sbjct: 195 PAWRMAGRIVGGME-ASPGEFPWQASLRE-NKEHFCGAAIINARWLVSAAHCFNEFQDPT 252
Query: 258 QWIATFGATI----TPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVC 313
+W+A GAT V+ V +I+ H Y+ +T + D+A+++L++ + F +Q VC
Sbjct: 253 KWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVC 312
Query: 314 LPDSSIKLPPKTSVFVTGFGSIVDDGPIQ-NTLRQARVETISTDVCNRKDVYDGLITPGM 372
LP ++ PP ++G+G + +D ++ L++A VE + +C +Y +T M
Sbjct: 313 LPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALC--ASLYGHSLTDRM 370
Query: 373 LCAGFMEGKIDACKGDSGGPLVYDN-HDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
+CAG+++GK+D+C+GDSGGPLV + +++ GIVSWG CA ++PGVY RVT+ RDW
Sbjct: 371 VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDW 430
Query: 432 IASKT 436
I T
Sbjct: 431 ILEAT 435
Score = 178 bits (452), Expect = 8e-45
Identities = 97/237 (40%), Positives = 133/237 (56%), Gaps = 6/237 (2%)
Query: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQ 258
A ++ RIV G A GEWPWQ SL L H+CGA L++ WLL+AAHCF DP Q
Sbjct: 820 APAALTRIVGG-SAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQ 878
Query: 259 WIATFGATITPPAVKR--NVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPD 316
W A G A + V +I H Y+ T + D+AL++L+ V S +V+ +CLP+
Sbjct: 879 WAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPE 938
Query: 317 SSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAG 376
+ + P T +TG+GS+ + G + L++A V +S C R Y I+ MLCAG
Sbjct: 939 PAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRR--FYPVQISSRMLCAG 996
Query: 377 FMEGKIDACKGDSGGPLV-YDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
F +G +D+C GD+GGPL + W + G+ SWG C P PGVYTRV R WI
Sbjct: 997 FPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053
Score = 162 bits (411), Expect = 4e-40
Identities = 94/241 (39%), Positives = 142/241 (58%), Gaps = 11/241 (4%)
Query: 198 PASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPT 257
PA R+V G A GE PWQ SL+ GS H CGA+++ + WLL+AAHCF K
Sbjct: 496 PAMEKPTRVVGGFGAA-SGEVPWQVSLKE-GSRHFCGATVVGDRWLLSAAHCFNHTK-VE 552
Query: 258 QWIATFGAT----ITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVC 313
Q A G + VK +R+++LH Y+ + D+A+++L++ + F+ +Q VC
Sbjct: 553 QVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVC 612
Query: 314 LPDSSIKLPPKTSVFVTGFGSIVDDGPIQ-NTLRQARVETISTDVCNRKDVYDGLITPGM 372
LP + K P ++G+G+ + + L++A V I C+ +Y+ +T M
Sbjct: 613 LPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSV--LYNFSLTDRM 670
Query: 373 LCAGFMEGKIDACKGDSGGPLVYDNHD-IWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
+CAGF+EGK+D+C+GDSGGPL + ++Y+ GIVSWG CA KKPGVYTR+T+ + W
Sbjct: 671 ICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGW 730
Query: 432 I 432
I
Sbjct: 731 I 731
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 185 bits (469), Expect = 8e-47
Identities = 102/250 (40%), Positives = 138/250 (55%), Gaps = 18/250 (7%)
Query: 205 RIVQGRETAMEGEWPWQASLQLIGSG----HQCGASLISNTWLLTAAHCFWKNKDPTQWI 260
RIV G+ A G WPW SLQ+ H CG SL+++ W+LTAAHCF + W
Sbjct: 42 RIVGGK-AAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWR 100
Query: 261 ATFGAT---------ITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQR 311
FGA + P +R V KII+HE Y+ T NDIALV+++ + +
Sbjct: 101 LVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGP 160
Query: 312 VCLPDSSIKLPPKT-SVFVTGFGSIVDDGPIQNT-LRQARVETISTDVCNRKDVYDGLIT 369
CLP LP + S +V G+G I + P ++ L +ARV+ I D+CN Y+G +
Sbjct: 161 GCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQ 220
Query: 370 PGMLCAGFMEGKIDACKGDSGGPLVY--DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTK 427
P +CAG+ GKID C+GDSGGPL+ + +VGI SWG CA K+PG+YT
Sbjct: 221 PTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWP 280
Query: 428 YRDWIASKTG 437
Y +WIASK G
Sbjct: 281 YLNWIASKIG 290
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 184 bits (466), Expect = 2e-46
Identities = 99/267 (37%), Positives = 155/267 (58%), Gaps = 14/267 (5%)
Query: 181 LLNSRCGIRMTSSNMPLPASSSTQRI---VQGRETAMEGEWPWQASLQLIG--SGHQCGA 235
+L+ R GI + + + T +I + G ++ GEWPWQ +L H CG
Sbjct: 359 ILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGG 418
Query: 236 SLISNTWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRN-----VRKIILHENYHRETN 290
S+I N W+LTAAHCF+ + P + + + + +K + V++II+H+ Y +
Sbjct: 419 SIIGNQWILTAAHCFYGVESP-KILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 477
Query: 291 ENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARV 350
DIAL++L T V +++ + +CLP + T +VTG+G IQNTL++A++
Sbjct: 478 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKI 537
Query: 351 ETISTDVCNRKDVYDG-LITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSW 409
++ + C ++ Y G IT M+CAG+ EG DACKGDSGGPL ++++W++VGI SW
Sbjct: 538 PLVTNEECQKR--YRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSW 595
Query: 410 GQSCALPKKPGVYTRVTKYRDWIASKT 436
G+ CA ++PGVYT V +Y DWI KT
Sbjct: 596 GEGCAQRERPGVYTNVVEYVDWILEKT 622
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 181 bits (460), Expect = 9e-46
Identities = 102/246 (41%), Positives = 142/246 (57%), Gaps = 15/246 (6%)
Query: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIAT 262
+ RIV GR+ +GEWPWQAS+Q G+ H CG SLI+ W+LTAAHCF + P ++
Sbjct: 34 SSRIVGGRD-GRDGEWPWQASIQHRGA-HVCGGSLIAPQWVLTAAHCFPRRALPAEYRVR 91
Query: 263 FGA----TITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318
GA + +P + VR+++L +Y + D+AL+QL V S VQ VCLP
Sbjct: 92 LGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPG 151
Query: 319 IKLPPKTSVFVTGFGSIVDDGPIQN--TLRQARVETISTDVCNR-----KDV--YDGLIT 369
+ PP T VTG+GS+ P+ L+ RV + + C+ DV + ++
Sbjct: 152 ARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVL 211
Query: 370 PGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYR 429
PG LCAG+ +G DAC+GDSGGPL W +VG+VSWG+ CALP +PGVYT V Y
Sbjct: 212 PGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYS 271
Query: 430 DWIASK 435
WI ++
Sbjct: 272 PWIQAR 277
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 181 bits (459), Expect = 1e-45
Identities = 103/265 (38%), Positives = 151/265 (56%), Gaps = 21/265 (7%)
Query: 175 SKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCG 234
S ++ +L S CG R +S RIV G+ A G WPWQAS+ L G H CG
Sbjct: 198 SGQVVSLRCSECGARPLAS-----------RIVGGQSVA-PGRWPWQASVAL-GFRHTCG 244
Query: 235 ASLISNTWLLTAAHCF--WKNKDPTQWIATFGATITPPAVKRN----VRKIILHENYHRE 288
S+++ W++TAAHC ++ + W G ++ AV+ + V +II H Y +
Sbjct: 245 GSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGL-VSHSAVRPHQGALVERIIPHPLYSAQ 303
Query: 289 TNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQA 348
++ D+AL++L T + FS+ V VCLP P + +V+G+G + + Q
Sbjct: 304 NHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQD 363
Query: 349 RVETI-STDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIV 407
V + ST +CN VY G +TP MLCAG+++G+ DAC+GDSGGPLV + D W +VG+V
Sbjct: 364 TVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVV 423
Query: 408 SWGQSCALPKKPGVYTRVTKYRDWI 432
SWG+ CA P PGVY +V ++ DWI
Sbjct: 424 SWGRGCAEPNHPGVYAKVAEFLDWI 448
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 180 bits (457), Expect = 2e-45
Identities = 107/242 (44%), Positives = 142/242 (58%), Gaps = 13/242 (5%)
Query: 199 ASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNK--DP 256
+SS+ RI+ G +T +EG WPWQ SL +GS + CGAS+IS WLL+AAHCF N+ DP
Sbjct: 473 SSSALHRIIGGTDT-LEGGWPWQVSLHFVGSAY-CGASVISREWLLSAAHCFHGNRLSDP 530
Query: 257 TQWIATFGATITPPA-VKRNVRKIILHENYHRETNENDIALVQLSTG--VEFSNIVQRVC 313
T W A G + A VR+I++HE Y+ +T + DIAL+QLS ++Q +C
Sbjct: 531 TPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPIC 590
Query: 314 LPDSSIKLPPKTSVFVTGFGSIVD-DGPIQNTLRQARVETISTDVCNRKDVYDGLITPGM 372
+P + ++ +VTG+G + D L+QA VE I +C Y G+IT M
Sbjct: 591 IPPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLC--VSTY-GIITSRM 647
Query: 373 LCAGFMEGKIDACKGDSGGPLV--YDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRD 430
LCAG M GK DACKGDSGGPL + W + GIVSWG P PGVYTRV+ +
Sbjct: 648 LCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVP 707
Query: 431 WI 432
WI
Sbjct: 708 WI 709
Score = 37.7 bits (86), Expect = 0.021
Identities = 21/98 (21%), Positives = 51/98 (52%)
Query: 65 FKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVD 124
F++TNI++ Y + SREF+ S ++++++ ++ S+ + +S V +S ++ G+
Sbjct: 2 FRITNIEFLPEYRQKESREFLSVSRTVQQVINLVYTTSAFSKFYEQSVVADVSNNKGGLL 61
Query: 125 ILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLT 162
+ ++F P + + L S++T ++ T
Sbjct: 62 VHFWIVFVMPRAKGHIFCEDCVAAILKDSIQTSIINRT 99
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 179 bits (455), Expect = 3e-45
Identities = 99/237 (41%), Positives = 141/237 (59%), Gaps = 11/237 (4%)
Query: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNK--DPTQWI 260
+ RIV G ++ EGEWPWQASLQ+ G H CG +LI++ W++TAAHCF ++ W
Sbjct: 574 SSRIVGGAVSS-EGEWPWQASLQVRGR-HICGGALIADRWVITAAHCFQEDSMASTVLWT 631
Query: 261 ATFGATIT----PPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPD 316
G P V V +++LH + ++++ D+AL+QL V S V+ VCLP
Sbjct: 632 VFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPA 691
Query: 317 SSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAG 376
S P ++TG+G++ + GPI N L++ V+ I D+C+ +VY +TP MLCAG
Sbjct: 692 RSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCS--EVYRYQVTPRMLCAG 749
Query: 377 FMEGKIDACKGDSGGPLVYDN-HDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
+ +GK DAC+GDSGGPLV W++ G+VSWG C P GVYTR+T WI
Sbjct: 750 YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 806
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 177 bits (449), Expect = 2e-44
Identities = 106/277 (38%), Positives = 151/277 (54%), Gaps = 33/277 (11%)
Query: 181 LLNSRCGIRMTSSNMPLPASSS------TQRIVQGRETAMEGEWPWQASLQLIGSGHQCG 234
LL +R G+R S P S T RIV G + + G WPWQ SL+L S H CG
Sbjct: 11 LLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAEL-GRWPWQGSLRLWDS-HVCG 68
Query: 235 ASLISNTWLLTAAHCFWKN-KDPTQWIATFGATITPPA--------VKRNVRKIILHENY 285
SL+S+ W LTAAHCF + DP+ W+ FG + P+ + V I L Y
Sbjct: 69 VSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY 128
Query: 286 HRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDG--PIQN 343
+ DIALV+LS V ++ +Q +CL S+ + +T +VTG+G I +D P +
Sbjct: 129 -LGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPH 187
Query: 344 TLRQARVETISTDVCN--------RKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVY 395
TL++ +V I+ +CN RKD++ M+CAG +G DAC GDSGGPL
Sbjct: 188 TLQEVQVAIINNSMCNHLFLKYSFRKDIFGD-----MVCAGNAQGGKDACFGDSGGPLAC 242
Query: 396 DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
+ + +WY +G+VSWG C P +PGVYT ++ + +WI
Sbjct: 243 NKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI 279
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 175 bits (444), Expect = 6e-44
Identities = 103/241 (42%), Positives = 135/241 (56%), Gaps = 15/241 (6%)
Query: 205 RIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFG 264
R+V G++T EGEWPWQ S+Q GS H CG SLI+ W+LTAAHCF + + + G
Sbjct: 34 RMVGGQDT-QEGEWPWQVSIQRNGS-HFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLG 91
Query: 265 ATIT----PPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIK 320
A P A+ VR++ + Y + D+ALV+L V F+N + VCLPD S+
Sbjct: 92 ARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVI 151
Query: 321 LPPKTSVFVTGFGSIVDDG--PIQNTLRQARVETISTDVCN---RKDVYDGL----ITPG 371
+ +VTG+GS ++ P L++ V I T CN KD G I
Sbjct: 152 FETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKND 211
Query: 372 MLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
MLCAGF EGK DACKGDSGGPLV W G++SWG+ CA +PGVY RVT + +W
Sbjct: 212 MLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNW 271
Query: 432 I 432
I
Sbjct: 272 I 272
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 175 bits (444), Expect = 6e-44
Identities = 106/279 (37%), Positives = 150/279 (53%), Gaps = 35/279 (12%)
Query: 181 LLNSRCGIRMTSSNMPLPASSS------TQRIVQGRETAMEGEWPWQASLQLIGSGHQCG 234
LL +R G+R S P S T RIV G + + G WPWQ SL+L S H CG
Sbjct: 11 LLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAEL-GRWPWQGSLRLWDS-HVCG 68
Query: 235 ASLISNTWLLTAAHCFWKNKD---PTQWIATFGATITPPA--------VKRNVRKIILHE 283
SL+S+ W LTAAHCF D P+ W+ FG + P+ + V I L
Sbjct: 69 VSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSP 128
Query: 284 NYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDG--PI 341
Y + DIALV+LS V ++ +Q +CL S+ + +T +VTG+G I +D P
Sbjct: 129 RY-LGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPS 187
Query: 342 QNTLRQARVETISTDVCN--------RKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPL 393
+TL++ +V I+ +CN RKD++ M+CAG +G DAC GDSGGPL
Sbjct: 188 PHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD-----MVCAGNAQGGKDACFGDSGGPL 242
Query: 394 VYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
+ + +WY +G+VSWG C P +PGVYT ++ + +WI
Sbjct: 243 ACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI 281
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 173 bits (439), Expect = 2e-43
Identities = 105/286 (36%), Positives = 159/286 (55%), Gaps = 18/286 (6%)
Query: 160 SLTINKPSFRLTPIDS--KKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGE 217
S ++NK +L P ++ ++ +L+ CGI P + R + G E A
Sbjct: 533 SESLNKFEPKLPPQNNPVSTVKAILHDVCGI-------PPFSPQWLSRRIAGGEEACPHC 585
Query: 218 WPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGA----TITPPAVK 273
WPWQ L+ +G +QCG ++I+ W+LTAAHC +P W G
Sbjct: 586 WPWQVGLRFLGD-YQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQV 644
Query: 274 RNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFG 333
R + II+HE+++ + ++DIAL+QLS+ +E++++V+ VCLP S+ L VTG+G
Sbjct: 645 RRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWG 704
Query: 334 SIVDDGPIQNTLRQARVETISTDVCNRK--DVYDGLITPGMLCAGF-MEGKIDACKGDSG 390
SI DG + + L+Q +V + +VC + G IT M+CAGF G+ D C+GDSG
Sbjct: 705 SISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSG 764
Query: 391 GPLVYDNHDIWYIV-GIVSWGQSCALPKKPGVYTRVTKYRDWIASK 435
GPLV + + +++ GIVSWG C P KPGV+ RV + DWI SK
Sbjct: 765 GPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSK 810
Score = 126 bits (317), Expect = 3e-29
Identities = 96/273 (35%), Positives = 128/273 (46%), Gaps = 24/273 (8%)
Query: 182 LNSRCGIRMTSSNMPLPASSST--QRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLIS 239
L +CGIRM + PA S RI R + + G PWQ SL+ H CG SLI
Sbjct: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGH-PWQVSLKS-DEHHFCGGSLIQ 78
Query: 240 NTWLLTAAHCF--WKNKDPTQWIATFGATITPPAVKRN----VRKIILHENYH-RETNEN 292
++TAAHC K T G K+ V KII H Y+ RE
Sbjct: 79 EDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP 138
Query: 293 DIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVET 352
DIAL+ L V+F N VQ +CLPDS K+ P +G+G I N L++ +
Sbjct: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
Query: 353 ISTDVCNR--KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLV-YDNHDIWYIVGIVSW 409
+ CN K + + MLCAGF + +DAC+GDSGGPLV IW + GI SW
Sbjct: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
Query: 410 GQSCALPKKP----------GVYTRVTKYRDWI 432
CA P G++++V++ D+I
Sbjct: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 173 bits (438), Expect = 3e-43
Identities = 106/305 (34%), Positives = 157/305 (51%), Gaps = 22/305 (7%)
Query: 137 DSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMP 196
+SA + + + S + + TI + S + S++ +L S CG+R
Sbjct: 269 ESAHRTTEVAHRDFANSFSILRYNSTIQE-SLHRSECPSQRYISLQCSHCGLR------- 320
Query: 197 LPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDP 256
+ T RIV G A + +WPWQ SL G+ H CG +LI W+LTAAHCF+ ++
Sbjct: 321 ----AMTGRIVGGA-LASDSKWPWQVSLHF-GTTHICGGTLIDAQWVLTAAHCFFVTREK 374
Query: 257 TQ-----WIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQR 311
+ T P A ++ +II++ NY E ++ DIAL++LS + S +
Sbjct: 375 VLEGWKVYAGTSNLHQLPEAA--SIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHP 432
Query: 312 VCLPDSSIKLPPKTSVFVTGFGSIVD-DGPIQNTLRQARVETISTDVCNRKDVYDGLITP 370
CLP + ++TGFG + D LR+ +V I CN VYD +TP
Sbjct: 433 ACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTP 492
Query: 371 GMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRD 430
M+CAG + G D+C+GDSGGPLV + ++ WY+ G+ SWG C KPGVYT+VT+
Sbjct: 493 RMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLP 552
Query: 431 WIASK 435
WI SK
Sbjct: 553 WIYSK 557
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 173 bits (438), Expect = 3e-43
Identities = 100/257 (38%), Positives = 152/257 (59%), Gaps = 15/257 (5%)
Query: 190 MTSSNMPLP-ASSSTQRI--VQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTA 246
+ ++ +P+P A Q++ V G E + + EWPW S+Q G+ H C SL+++ W++TA
Sbjct: 30 LNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGT-HHCAGSLLTSRWVITA 88
Query: 247 AHCFWKNKD-PTQWIATFGA-TITPP---AVKRNVRKIILHENYH-RETNENDIALVQLS 300
AHCF N + P + GA + P + K V + H Y +E DIALV+L
Sbjct: 89 AHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLE 148
Query: 301 TGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQN--TLRQARVETISTDVC 358
++FS V +CLPD+SI LPP T +++G+GSI D P+ + TL++ +V I ++VC
Sbjct: 149 RSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVC 208
Query: 359 NR---KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCAL 415
+ + G IT MLCAG++EG+ DAC GDSGGPL+ W + GI+SWG+ CA
Sbjct: 209 SHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAE 268
Query: 416 PKKPGVYTRVTKYRDWI 432
+PGVY ++ +R W+
Sbjct: 269 RNRPGVYISLSAHRSWV 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,685,801
Number of Sequences: 37866
Number of extensions: 643612
Number of successful extensions: 1979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1312
Number of HSP's gapped (non-prelim): 226
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.