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Search of human proteins with 189491645
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189491645 fibulin 7 isoform 1 [Homo sapiens]
(439 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189491645 fibulin 7 isoform 1 [Homo sapiens] 926 0.0
gi|189491647 fibulin 7 isoform 2 [Homo sapiens] 671 0.0
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 165 9e-41
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 149 5e-36
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 149 5e-36
gi|19743803 fibulin 5 precursor [Homo sapiens] 140 2e-33
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 134 2e-31
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 134 2e-31
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 134 2e-31
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 134 2e-31
gi|34734066 fibulin 1 isoform D [Homo sapiens] 127 3e-29
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 116 4e-26
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 116 4e-26
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 116 4e-26
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 111 1e-24
gi|118572606 hemicentin 1 [Homo sapiens] 108 1e-23
gi|4557733 latent transforming growth factor beta binding protei... 107 3e-23
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 105 6e-23
gi|56237021 fibrillin 3 precursor [Homo sapiens] 104 1e-22
gi|88758613 CD93 antigen precursor [Homo sapiens] 103 2e-22
gi|66346695 fibrillin 2 precursor [Homo sapiens] 103 3e-22
gi|24430141 fibrillin 1 precursor [Homo sapiens] 102 5e-22
gi|110347437 latent transforming growth factor beta binding prot... 102 5e-22
gi|110347412 latent transforming growth factor beta binding prot... 102 5e-22
gi|110347431 latent transforming growth factor beta binding prot... 102 5e-22
gi|192447438 protein S, alpha preproprotein [Homo sapiens] 100 3e-21
gi|46249414 latent transforming growth factor beta binding prote... 99 1e-20
gi|46249412 latent transforming growth factor beta binding prote... 99 1e-20
gi|4557679 jagged 1 precursor [Homo sapiens] 97 3e-20
gi|194328809 latent transforming growth factor beta binding prot... 97 3e-20
>gi|189491645 fibulin 7 isoform 1 [Homo sapiens]
Length = 439
Score = 926 bits (2393), Expect = 0.0
Identities = 439/439 (100%), Positives = 439/439 (100%)
Query: 1 MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS 60
MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS
Sbjct: 1 MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS 60
Query: 61 RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV 120
RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV
Sbjct: 61 RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV 120
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP
Sbjct: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
Query: 181 EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC
Sbjct: 181 EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
Query: 241 MHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE 300
MHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE
Sbjct: 241 MHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE 300
Query: 301 CPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATA 360
CPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATA
Sbjct: 301 CPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATA 360
Query: 361 SAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDR 420
SAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDR
Sbjct: 361 SAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDR 420
Query: 421 SFQANHVSKVTIFVSPYDF 439
SFQANHVSKVTIFVSPYDF
Sbjct: 421 SFQANHVSKVTIFVSPYDF 439
>gi|189491647 fibulin 7 isoform 2 [Homo sapiens]
Length = 393
Score = 671 bits (1730), Expect = 0.0
Identities = 341/443 (76%), Positives = 351/443 (79%), Gaps = 54/443 (12%)
Query: 1 MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS 60
MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS
Sbjct: 1 MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKS 60
Query: 61 RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV 120
RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV
Sbjct: 61 RLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVV 120
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQT
Sbjct: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTDVN 180
Query: 181 EGSVAGDSAFSR--APRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPR 238
E + G R C + C+C G+ A C+DV+EC G
Sbjct: 181 ECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRT--LADGKSCEDVDEC-----VGLQP 233
Query: 239 LCMH--ACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
+C C+NT GS++C
Sbjct: 234 VCPQGTTCINTGGSFQC------------------------------------------- 250
Query: 297 VSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFR 356
VSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFR
Sbjct: 251 VSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFR 310
Query: 357 MATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSE 416
MATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSE
Sbjct: 311 MATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSE 370
Query: 417 YLDRSFQANHVSKVTIFVSPYDF 439
YLDRSFQANHVSKVTIFVSPYDF
Sbjct: 371 YLDRSFQANHVSKVTIFVSPYDF 393
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 165 bits (417), Expect = 9e-41
Identities = 105/346 (30%), Positives = 168/346 (48%), Gaps = 55/346 (15%)
Query: 130 EQPHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGR------------------TGN 169
E C + EC+ ++PC G CV +RC C G G
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 170 RCQHQAQTA--------------APEGSVAGD----SAFSRAPRCAQVERAQHCSCEAGF 211
C H+ + + +G D S+ + CA V + C C G+
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGY 469
Query: 212 HLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPG-GYRTLADGKSCED 270
LS G + C+D++EC L +C + C+N PGS++C+CP GYR +G++C+D
Sbjct: 470 QLSDVDGVT-CEDIDECAL---PTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Query: 271 VDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
+DECV C TC N G F+C++ ECPE +Y +++ +CER PC ++R C
Sbjct: 526 IDECVTGIHNCSINETCFNIQGGFRCLAFECPE-----NYRRSAATRCERLPC-HENREC 579
Query: 331 RHLPKTISFHYLSLPSNLKTPITLFRMATASA-PGRAGPNSLRFGIVGGNSRGHFVMQRS 389
LP I++++LS P+N++ P +FRM +SA PG +S++ I GGN G F ++
Sbjct: 580 SKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPG----DSMQLAITGGNEEGFFTTRKV 635
Query: 390 DRQTGDLILVQNLEGPQTLEVDVDMSEYLDRSFQANHVSKVTIFVS 435
+G + L + + P+ L + V M + ++ V+K+ IFVS
Sbjct: 636 SPHSGVVALTKPVPEPRDLLLTVKM-DLSRHGTVSSFVAKLFIFVS 680
Score = 63.9 bits (154), Expect = 3e-10
Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 19/133 (14%)
Query: 205 CSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMHACVNTPGSYRC----TCPGGY 259
CSC G+ L D V C+DVNEC R +C+NT GS+RC +C GY
Sbjct: 199 CSCFVGYQL---LSDGVSCEDVNECITGSHSCR---LGESCINTVGSFRCQRDSSCGTGY 252
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC-VSPECPEGSGNVSYVKTSPFQC 318
L + SC+D+DEC C C NT GSF+C +C G +++ + C
Sbjct: 253 E-LTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG-----FIQDALGNC 306
Query: 319 -ERNPCPMDSRPC 330
+ N C S PC
Sbjct: 307 IDINECLSISAPC 319
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 30/213 (14%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVN----QYRCIC 162
C G R+ LP T E CR + E C G++ Q RC
Sbjct: 37 CADGHRMATHQKDCSLPYAT---ESKECRMVQEQCCHSQLEELHCATGISLANEQDRCAT 93
Query: 163 PPGRTGN-------RCQHQAQT--AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHL 213
P G + RC H AA + + + +C QV RA C
Sbjct: 94 PHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRA----CCVKSQE 149
Query: 214 SGAAGDSVCQDVNEC-ELYGQEGRPRL---------CMHACVNTPGSYRCTCPGGYRTLA 263
+G Q+ ++ E+ ++ P L C C +T C+C GY+ L+
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 264 DGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
DG SCEDV+EC+ C G +CINT GSF+C
Sbjct: 210 DGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 149 bits (376), Expect = 5e-36
Identities = 99/312 (31%), Positives = 150/312 (48%), Gaps = 36/312 (11%)
Query: 134 CRGISECSSQP---CQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSVAG 186
C ++EC + P CQ+ TC + YRC C G G RC+ + A S
Sbjct: 899 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCS--- 953
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVN 246
CA + + C C G+ L A C D++EC +G LC C+N
Sbjct: 954 -------QECANIYGSYQCYCRQGYQL--AEDGHTCTDIDECA----QGAGILCTFRCLN 1000
Query: 247 TPGSYRCTCPG-GYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
PGSY+C CP GY A+G+SC+DVDEC C + TC N GSF+C+ ECP
Sbjct: 1001 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP-- 1058
Query: 306 GNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGR 365
+YV+ S +CER C D C++ P I+ + L+ + L P +FR+ AP
Sbjct: 1059 ---NYVQVSKTKCERTTC-HDFLECQNSPARITHYQLNFQTGLLVPAHIFRI--GPAPAF 1112
Query: 366 AGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDRSFQAN 425
G +++ I+ GN G+F +R + TG + L + + P+ +DV+M + S
Sbjct: 1113 TG-DTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSV-TT 1170
Query: 426 HVSKVTIFVSPY 437
++K+ IF + +
Sbjct: 1171 FLAKMHIFFTTF 1182
Score = 78.6 bits (192), Expect = 1e-14
Identities = 76/248 (30%), Positives = 104/248 (41%), Gaps = 59/248 (23%)
Query: 122 LPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----GNRCQ---HQ 174
LPN +Q C + + CQ+ C+ V Y C C PG + G C+ H
Sbjct: 596 LPNSLPGDDQDECLLLP---GELCQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHP 650
Query: 175 AQTAAPE--------GSVAGDSAFSRAPR-------------CAQVERAQHCSCEAGFHL 213
Q AP+ VA ++ P+ C+ V + CSC G+ +
Sbjct: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAI 710
Query: 214 SGAAGDSVCQDVNEC--ELYGQEGRPRLCMHA--CVNTPGSYRC----TCPGGYRTLADG 265
A C+D+NEC +L+ C CVNT GS+ C TC GY L DG
Sbjct: 711 M--ADGVSCEDINECVTDLH-------TCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG 760
Query: 266 KSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE-CPEGSGNVSYVKTSPFQC-ERNPC 323
+ CEDVDEC C G C NT GSF C + + C +G +++ C + N C
Sbjct: 761 E-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG-----FLQDPEGNCVDINEC 814
Query: 324 PMDSRPCR 331
S PCR
Sbjct: 815 TSLSEPCR 822
Score = 29.3 bits (64), Expect = 7.4
Identities = 31/160 (19%), Positives = 42/160 (26%), Gaps = 47/160 (29%)
Query: 114 VGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCV---------EGVNQYRCI--- 161
+GPS P TG + C + C + + G C EG Y C+
Sbjct: 20 LGPSVAAAAPRQDCTGVE--CPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGG 77
Query: 162 ----------------------CPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQV 199
CPPG CQ P + P+C QV
Sbjct: 78 FVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQV 137
Query: 200 -----------ERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
H H A G+ +C + C
Sbjct: 138 GCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGC 177
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 149 bits (376), Expect = 5e-36
Identities = 99/312 (31%), Positives = 150/312 (48%), Gaps = 36/312 (11%)
Query: 134 CRGISECSSQP---CQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSVAG 186
C ++EC + P CQ+ TC + YRC C G G RC+ + A S
Sbjct: 946 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCS--- 1000
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVN 246
CA + + C C G+ L A C D++EC +G LC C+N
Sbjct: 1001 -------QECANIYGSYQCYCRQGYQL--AEDGHTCTDIDECA----QGAGILCTFRCLN 1047
Query: 247 TPGSYRCTCPG-GYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
PGSY+C CP GY A+G+SC+DVDEC C + TC N GSF+C+ ECP
Sbjct: 1048 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP-- 1105
Query: 306 GNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGR 365
+YV+ S +CER C D C++ P I+ + L+ + L P +FR+ AP
Sbjct: 1106 ---NYVQVSKTKCERTTC-HDFLECQNSPARITHYQLNFQTGLLVPAHIFRI--GPAPAF 1159
Query: 366 AGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDRSFQAN 425
G +++ I+ GN G+F +R + TG + L + + P+ +DV+M + S
Sbjct: 1160 TG-DTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSV-TT 1217
Query: 426 HVSKVTIFVSPY 437
++K+ IF + +
Sbjct: 1218 FLAKMHIFFTTF 1229
Score = 73.2 bits (178), Expect = 4e-13
Identities = 68/229 (29%), Positives = 94/229 (41%), Gaps = 43/229 (18%)
Query: 122 LPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPE 181
LPN +Q C + + CQ+ C+ V Y C C PG + Q +T PE
Sbjct: 596 LPNSLPGDDQDECLLLP---GELCQH--LCINTVGSYHCACFPGFS---LQDDGRTCRPE 647
Query: 182 GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV---CQDVNECELYGQEGRPR 238
G Q E Q + ++ F S A +++ N C+ G
Sbjct: 648 GHPP------------QPEAPQEPALKSEF--SQVASNTIPLPLPQPNTCKDNGP----- 688
Query: 239 LCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVS 298
C C GS C+C GY +ADG SCED DEC+ C + C+NT GSF CV+
Sbjct: 689 -CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVN 747
Query: 299 PE--CPEGSGNVSYVKTSPFQC-ERNPCPMDSRPC---RHLPKTI-SFH 340
C +G Y+ + +C + N C D C H T+ SFH
Sbjct: 748 HTVLCADG-----YILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFH 791
Score = 65.9 bits (159), Expect = 7e-11
Identities = 78/266 (29%), Positives = 106/266 (39%), Gaps = 62/266 (23%)
Query: 104 HFTCNPGFRLVGPSSVVCLPNG----TWTGEQPHCRG-ISECSS--------QP--CQNG 148
H C PGF L C P G ++P + S+ +S QP C++
Sbjct: 628 HCACFPGFSLQDDGRT-CRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDN 686
Query: 149 GTCVEGVNQYR----CICPPGRT----GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVE 200
G C + + C C PG G C+ Q + + G SR C
Sbjct: 687 GPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDEC------LMGAHDCSRRQFCVNTL 740
Query: 201 RAQHCS-----CEAGFHLSGAAGDSVCQDVNEC--ELYGQEGRPRLCMHA--CVNTPGSY 251
+ +C C G+ L+ C D+NEC +L+ C CVNT GS+
Sbjct: 741 GSFYCVNHTVLCADGYILNA---HRKCVDINECVTDLH-------TCSRGEHCVNTLGSF 790
Query: 252 RC----TCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE-CPEGSG 306
C TC GY L DG+ CEDVDEC C G C NT GSF C + + C +G
Sbjct: 791 HCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG-- 846
Query: 307 NVSYVKTSPFQC-ERNPCPMDSRPCR 331
+++ C + N C S PCR
Sbjct: 847 ---FLQDPEGNCVDINECTSLSEPCR 869
Score = 29.3 bits (64), Expect = 7.4
Identities = 31/160 (19%), Positives = 42/160 (26%), Gaps = 47/160 (29%)
Query: 114 VGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCV---------EGVNQYRCI--- 161
+GPS P TG + C + C + + G C EG Y C+
Sbjct: 20 LGPSVAAAAPRQDCTGVE--CPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGG 77
Query: 162 ----------------------CPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQV 199
CPPG CQ P + P+C QV
Sbjct: 78 FVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQV 137
Query: 200 -----------ERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
H H A G+ +C + C
Sbjct: 138 GCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGC 177
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 140 bits (353), Expect = 2e-33
Identities = 99/324 (30%), Positives = 146/324 (45%), Gaps = 40/324 (12%)
Query: 124 NGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQTAA 179
+G W E C I EC CQ C Y C C PG T G CQ + A
Sbjct: 157 DGYWLLEG-QCLDIDECRYGYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT 213
Query: 180 PEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPR 238
V C + C C+ G+ L D V C D++EC
Sbjct: 214 ENPCVQ---------TCVNTYGSFICRCDPGYELEE---DGVHCSDMDECSF-----SEF 256
Query: 239 LCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVS 298
LC H CVN PG+Y C+CP GY L D +SC+D++EC C TC N G F+C+
Sbjct: 257 LCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCID 316
Query: 299 P-ECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRM 357
P C E Y++ S +C CP ++ CR P TI + + + S P +F+M
Sbjct: 317 PIRCEE-----PYLRISDNRC---MCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQM 368
Query: 358 -ATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDM-S 415
AT PG F I GN F M+++ + L++ + ++GP+ +++D++M +
Sbjct: 369 QATTRYPGA----YYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMIT 424
Query: 416 EYLDRSFQANHVSKVTIFVSPYDF 439
+F+ + V ++ I+VS Y F
Sbjct: 425 VNTVINFRGSSVIRLRIYVSQYPF 448
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 52/203 (25%)
Query: 134 CRGISECSSQP--CQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP-EGSVAGDSAF 190
C I EC + P C+ CV Y CI P R + + P G +
Sbjct: 40 CLDIDECRTIPEACRGDMMCVNQNGGYLCI-PRTNPVYRGPYSNPYSTPYSGPYPAAAPP 98
Query: 191 SRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
AP + R C G+ + + + C DV+EC + P C+NT G
Sbjct: 99 LSAPNYPTISRP--LICRFGYQMDES---NQCVDVDECATDSHQCNPT---QICINTEGG 150
Query: 251 YRCTCPGGYRTL-------------------------------------ADGKSCEDVDE 273
Y C+C GY L DG+SC+DV+E
Sbjct: 151 YTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNE 210
Query: 274 CVGLQPVCPQGTTCINTGGSFQC 296
C P C Q TC+NT GSF C
Sbjct: 211 CATENP-CVQ--TCVNTYGSFIC 230
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 244 CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPE 303
C+ +PG+ + C G+ C D+DEC + C C+N G + C+ P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPV 75
Query: 304 GSGNVSYVKTSPFQCERNPCPMDSRP 329
G S ++P+ P P + P
Sbjct: 76 YRGPYSNPYSTPYS---GPYPAAAPP 98
Score = 37.0 bits (84), Expect = 0.036
Identities = 34/141 (24%), Positives = 44/141 (31%), Gaps = 52/141 (36%)
Query: 207 CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCT------------ 254
C GF L +G C D++EC + R + CVN G Y C
Sbjct: 27 CTNGFDLDRQSGQ--CLDIDECRTIPEACRGDMM---CVNQNGGYLCIPRTNPVYRGPYS 81
Query: 255 -------------------------------CPGGYRTLADGKSCEDVDECVGLQPVCPQ 283
C GY+ + + C DVDEC C
Sbjct: 82 NPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQ-MDESNQCVDVDECATDSHQCNP 140
Query: 284 GTTCINTGGSFQCVSPECPEG 304
CINT G + C C +G
Sbjct: 141 TQICINTEGGYTC---SCTDG 158
Score = 32.7 bits (73), Expect = 0.67
Identities = 27/108 (25%), Positives = 32/108 (29%), Gaps = 36/108 (33%)
Query: 106 TCNPGFRL--------------------------VGPSSVVCLPNGTWTGEQPHCRGISE 139
TCNPGF L G C P + HC + E
Sbjct: 191 TCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDE 250
Query: 140 CSSQPCQNGGTCVEGVNQYRCICPPG----------RTGNRCQHQAQT 177
CS CV Y C CPPG + N C+H+ T
Sbjct: 251 CSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHT 298
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 134 bits (337), Expect = 2e-31
Identities = 98/340 (28%), Positives = 148/340 (43%), Gaps = 52/340 (15%)
Query: 106 TCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG 165
TC G+R +GP C I EC + CQ+ CV +RC C PG
Sbjct: 150 TCPDGYRKIGPE----------------CVDIDECRYRYCQH--RCVNLPGSFRCQCEPG 191
Query: 166 ---RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVC 222
NR D RC C C G+ L C
Sbjct: 192 FQLGPNNRSCVDVNEC--------DMGAPCEQRCFNSYGTFLCRCHQGYELH--RDGFSC 241
Query: 223 QDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282
D++EC LC + CVN PG + C CP GY+ LA + C+D+DEC C
Sbjct: 242 SDIDECSYSSY-----LCQYRCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCS 295
Query: 283 QGTTCINTGGSFQCV-SPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHY 341
+ TC+N G ++CV + C E Y++ S +C CP + CR P +I Y
Sbjct: 296 EAQTCVNFHGGYRCVDTNRCVE-----PYIQVSENRC---LCPASNPLCREQPSSIVHRY 347
Query: 342 LSLPSNLKTPITLFRM-ATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQ 400
+++ S P +F++ AT+ PG F I GNS+G F +++ + + L+L +
Sbjct: 348 MTITSERSVPADVFQIQATSVYPGAYN----AFQIRAGNSQGDFYIRQINNVSAMLVLAR 403
Query: 401 NLEGPQTLEVDVDMSEYLD-RSFQANHVSKVTIFVSPYDF 439
+ GP+ +D++M S++A+ V ++T+FV Y F
Sbjct: 404 PVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF 443
>gi|86788132 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 134 bits (336), Expect = 2e-31
Identities = 100/366 (27%), Positives = 155/366 (42%), Gaps = 67/366 (18%)
Query: 116 PSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPPG--RTGNRC 171
PS + G E C+ I EC++ C+ C+ + C CPPG + G +C
Sbjct: 153 PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC 212
Query: 172 QHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELY 231
+ P RC + +C C GF L AA + C D+NEC+
Sbjct: 213 VDIDECTIPPYC---------HQRCVNTPGSFYCQCSPGFQL--AANNYTCVDINECDAS 261
Query: 232 GQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTG 291
Q C C N GS+ C C GY +D +CED+DEC +C C+N
Sbjct: 262 NQ------CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEP 313
Query: 292 GSFQCVSP---------------------ECPEGSGNVSYVKTSPFQC-ERNP------- 322
G F C+ P EC E +Y F+C RNP
Sbjct: 314 GKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNY--HGGFRCYPRNPCQDPYIL 371
Query: 323 -------CPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGRAGPNSLR-FG 374
CP+ + CR LP++I + Y+S+ S+ P +F++ + N++ F
Sbjct: 372 TPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA----NTINTFR 427
Query: 375 IVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLD-RSFQANHVSKVTIF 433
I GN G F ++++ + L+LV++L GP+ VD++M +F+ + V ++TI
Sbjct: 428 IKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTII 487
Query: 434 VSPYDF 439
V P+ F
Sbjct: 488 VGPFSF 493
Score = 35.4 bits (80), Expect = 0.10
Identities = 14/43 (32%), Positives = 21/43 (48%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C GY + C+D+DEC + C G C+N G + C+
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCL 71
>gi|86788015 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 134 bits (336), Expect = 2e-31
Identities = 100/366 (27%), Positives = 155/366 (42%), Gaps = 67/366 (18%)
Query: 116 PSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPPG--RTGNRC 171
PS + G E C+ I EC++ C+ C+ + C CPPG + G +C
Sbjct: 153 PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC 212
Query: 172 QHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELY 231
+ P RC + +C C GF L AA + C D+NEC+
Sbjct: 213 VDIDECTIPPYC---------HQRCVNTPGSFYCQCSPGFQL--AANNYTCVDINECDAS 261
Query: 232 GQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTG 291
Q C C N GS+ C C GY +D +CED+DEC +C C+N
Sbjct: 262 NQ------CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEP 313
Query: 292 GSFQCVSP---------------------ECPEGSGNVSYVKTSPFQC-ERNP------- 322
G F C+ P EC E +Y F+C RNP
Sbjct: 314 GKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNY--HGGFRCYPRNPCQDPYIL 371
Query: 323 -------CPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGRAGPNSLR-FG 374
CP+ + CR LP++I + Y+S+ S+ P +F++ + N++ F
Sbjct: 372 TPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA----NTINTFR 427
Query: 375 IVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLD-RSFQANHVSKVTIF 433
I GN G F ++++ + L+LV++L GP+ VD++M +F+ + V ++TI
Sbjct: 428 IKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTII 487
Query: 434 VSPYDF 439
V P+ F
Sbjct: 488 VGPFSF 493
Score = 35.4 bits (80), Expect = 0.10
Identities = 14/43 (32%), Positives = 21/43 (48%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C GY + C+D+DEC + C G C+N G + C+
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCL 71
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 134 bits (336), Expect = 2e-31
Identities = 100/366 (27%), Positives = 155/366 (42%), Gaps = 67/366 (18%)
Query: 116 PSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPPG--RTGNRC 171
PS + G E C+ I EC++ C+ C+ + C CPPG + G +C
Sbjct: 153 PSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC 212
Query: 172 QHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELY 231
+ P RC + +C C GF L AA + C D+NEC+
Sbjct: 213 VDIDECTIPPYC---------HQRCVNTPGSFYCQCSPGFQL--AANNYTCVDINECDAS 261
Query: 232 GQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTG 291
Q C C N GS+ C C GY +D +CED+DEC +C C+N
Sbjct: 262 NQ------CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEP 313
Query: 292 GSFQCVSP---------------------ECPEGSGNVSYVKTSPFQC-ERNP------- 322
G F C+ P EC E +Y F+C RNP
Sbjct: 314 GKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNY--HGGFRCYPRNPCQDPYIL 371
Query: 323 -------CPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGRAGPNSLR-FG 374
CP+ + CR LP++I + Y+S+ S+ P +F++ + N++ F
Sbjct: 372 TPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA----NTINTFR 427
Query: 375 IVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLD-RSFQANHVSKVTIF 433
I GN G F ++++ + L+LV++L GP+ VD++M +F+ + V ++TI
Sbjct: 428 IKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTII 487
Query: 434 VSPYDF 439
V P+ F
Sbjct: 488 VGPFSF 493
Score = 35.4 bits (80), Expect = 0.10
Identities = 14/43 (32%), Positives = 21/43 (48%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C GY + C+D+DEC + C G C+N G + C+
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCL 71
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 127 bits (318), Expect = 3e-29
Identities = 98/358 (27%), Positives = 152/358 (42%), Gaps = 52/358 (14%)
Query: 130 EQPHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGR------------------TGN 169
E C + EC+ ++PC G CV +RC C G G
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 170 RCQHQAQTA--------------APEGSVAGD----SAFSRAPRCAQVERAQHCSCEAGF 211
C H+ + + +G D S+ + CA V + C C G+
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGY 469
Query: 212 HLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPG-GYRTLADGKSCED 270
LS G + C+D++EC L +C + C+N PGS++C+CP GYR +G++C+D
Sbjct: 470 QLSDVDGVT-CEDIDECAL---PTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Query: 271 VDECVGLQPVCPQGTTCINTGGSFQCVSPECPE----GSGNVSYVKTSPFQCERNPCPMD 326
+DECV C TC N G F+C++ ECPE + + KT +C ++ P D
Sbjct: 526 IDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPND 585
Query: 327 SRPCRHLPKTISFHYLSLPS--NLKTPITLFRMATASAPGRAGPNSLRFGIVGGNSRGHF 384
TIS +SLP+ P + + + P A ++ F I GN R F
Sbjct: 586 VTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSF 645
Query: 385 --VMQRSDRQT-GDLILVQNLEGPQTLEVDVDMSEYLDRSFQANHVSKVTIFVSPYDF 439
+ + D T G + V+ + GP + ++M+ + +V V IFVS Y F
Sbjct: 646 DIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF 703
Score = 63.9 bits (154), Expect = 3e-10
Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 19/133 (14%)
Query: 205 CSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMHACVNTPGSYRC----TCPGGY 259
CSC G+ L D V C+DVNEC R +C+NT GS+RC +C GY
Sbjct: 199 CSCFVGYQL---LSDGVSCEDVNECITGSHSCR---LGESCINTVGSFRCQRDSSCGTGY 252
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC-VSPECPEGSGNVSYVKTSPFQC 318
L + SC+D+DEC C C NT GSF+C +C G +++ + C
Sbjct: 253 E-LTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG-----FIQDALGNC 306
Query: 319 -ERNPCPMDSRPC 330
+ N C S PC
Sbjct: 307 IDINECLSISAPC 319
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 30/213 (14%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVN----QYRCIC 162
C G R+ LP T E CR + E C G++ Q RC
Sbjct: 37 CADGHRMATHQKDCSLPYAT---ESKECRMVQEQCCHSQLEELHCATGISLANEQDRCAT 93
Query: 163 PPGRTGN-------RCQHQAQT--AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHL 213
P G + RC H AA + + + +C QV RA C
Sbjct: 94 PHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRA----CCVKSQE 149
Query: 214 SGAAGDSVCQDVNEC-ELYGQEGRPRL---------CMHACVNTPGSYRCTCPGGYRTLA 263
+G Q+ ++ E+ ++ P L C C +T C+C GY+ L+
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 264 DGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
DG SCEDV+EC+ C G +CINT GSF+C
Sbjct: 210 DGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 116 bits (291), Expect = 4e-26
Identities = 88/283 (31%), Positives = 116/283 (40%), Gaps = 56/283 (19%)
Query: 106 TCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG 165
+C G+R+ GPS LP C ++EC P C YRC+CPPG
Sbjct: 3555 SCPRGYRMQGPS----LP----------CLDVNECLQLPKACAYQCHNLQGSYRCLCPPG 3600
Query: 166 RT----GNRC---QHQAQTAA-------------PEGSVAGDSAF---SRAPRCAQVERA 202
+T G C + Q P S+ G S S P +
Sbjct: 3601 QTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSV 3660
Query: 203 QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTL 262
C GF + VC D++EC + LC HAC NT GSY+C CP GYR L
Sbjct: 3661 GRAWCPPGF----IRQNGVCTDLDECRVRN------LCQHACRNTEGSYQCLCPAGYRLL 3710
Query: 263 ADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVK-TSPFQCERN 321
GK+C+D++EC C G C NT GS+QCV CP +Y + SP C R
Sbjct: 3711 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCP-----ATYRQGPSPGTCFRR 3765
Query: 322 PCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPG 364
C D P T+ + L LP ++ + R+ S G
Sbjct: 3766 -CSQDCGTGG--PSTLQYRLLPLPLGVRAHHDVARLTAFSEVG 3805
Score = 84.3 bits (207), Expect = 2e-16
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 25/152 (16%)
Query: 170 RCQHQAQTAAPEG----------SVAGDSAFSRAPRCAQVERA-------QHCSCEAGFH 212
RC H Q A G + A SAF + + A C GF
Sbjct: 3374 RCNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFE 3433
Query: 213 LSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVD 272
L + C D +EC G P C HAC+N PG + CTCP G+ D ++C DVD
Sbjct: 3434 LDSQG--AFCVDRDECS-----GGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 273 ECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
EC +C +G C+N GS++C+ P+C G
Sbjct: 3487 ECAWDAHLCREGQRCVNLLGSYRCL-PDCGPG 3517
Score = 82.8 bits (203), Expect = 6e-16
Identities = 57/176 (32%), Positives = 77/176 (43%), Gaps = 21/176 (11%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR- 192
C ECS P C+ ++ C CP TG + A D+ R
Sbjct: 3441 CVDRDECSGGPSPCSHACLNAPGRFSCTCP---TGFALAWDDRNCRDVDECAWDAHLCRE 3497
Query: 193 APRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMH--ACVNTP 248
RC + + C C GF ++ AG C+DV+EC L G + C + C NTP
Sbjct: 3498 GQRCVNLLGSYRCLPDCGPGFRVADGAG---CEDVDEC-LEGLDD----CHYNQLCENTP 3549
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
G +RC+CP GYR C DV+EC+ L C C N GS++C+ CP G
Sbjct: 3550 GGHRCSCPRGYRMQGPSLPCLDVNECLQLPKAC--AYQCHNLQGSYRCL---CPPG 3600
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 116 bits (291), Expect = 4e-26
Identities = 88/283 (31%), Positives = 116/283 (40%), Gaps = 56/283 (19%)
Query: 106 TCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG 165
+C G+R+ GPS LP C ++EC P C YRC+CPPG
Sbjct: 4746 SCPRGYRMQGPS----LP----------CLDVNECLQLPKACAYQCHNLQGSYRCLCPPG 4791
Query: 166 RT----GNRC---QHQAQTAA-------------PEGSVAGDSAF---SRAPRCAQVERA 202
+T G C + Q P S+ G S S P +
Sbjct: 4792 QTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSV 4851
Query: 203 QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTL 262
C GF + VC D++EC + LC HAC NT GSY+C CP GYR L
Sbjct: 4852 GRAWCPPGF----IRQNGVCTDLDECRVRN------LCQHACRNTEGSYQCLCPAGYRLL 4901
Query: 263 ADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVK-TSPFQCERN 321
GK+C+D++EC C G C NT GS+QCV CP +Y + SP C R
Sbjct: 4902 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCP-----ATYRQGPSPGTCFRR 4956
Query: 322 PCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPG 364
C D P T+ + L LP ++ + R+ S G
Sbjct: 4957 -CSQDCGTGG--PSTLQYRLLPLPLGVRAHHDVARLTAFSEVG 4996
Score = 84.3 bits (207), Expect = 2e-16
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 25/152 (16%)
Query: 170 RCQHQAQTAAPEG----------SVAGDSAFSRAPRCAQVERA-------QHCSCEAGFH 212
RC H Q A G + A SAF + + A C GF
Sbjct: 4565 RCNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFE 4624
Query: 213 LSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVD 272
L + C D +EC G P C HAC+N PG + CTCP G+ D ++C DVD
Sbjct: 4625 LDSQG--AFCVDRDECS-----GGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 273 ECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
EC +C +G C+N GS++C+ P+C G
Sbjct: 4678 ECAWDAHLCREGQRCVNLLGSYRCL-PDCGPG 4708
Score = 82.8 bits (203), Expect = 6e-16
Identities = 57/176 (32%), Positives = 77/176 (43%), Gaps = 21/176 (11%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR- 192
C ECS P C+ ++ C CP TG + A D+ R
Sbjct: 4632 CVDRDECSGGPSPCSHACLNAPGRFSCTCP---TGFALAWDDRNCRDVDECAWDAHLCRE 4688
Query: 193 APRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMH--ACVNTP 248
RC + + C C GF ++ AG C+DV+EC L G + C + C NTP
Sbjct: 4689 GQRCVNLLGSYRCLPDCGPGFRVADGAG---CEDVDEC-LEGLDD----CHYNQLCENTP 4740
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
G +RC+CP GYR C DV+EC+ L C C N GS++C+ CP G
Sbjct: 4741 GGHRCSCPRGYRMQGPSLPCLDVNECLQLPKAC--AYQCHNLQGSYRCL---CPPG 4791
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 116 bits (291), Expect = 4e-26
Identities = 88/283 (31%), Positives = 116/283 (40%), Gaps = 56/283 (19%)
Query: 106 TCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG 165
+C G+R+ GPS LP C ++EC P C YRC+CPPG
Sbjct: 3464 SCPRGYRMQGPS----LP----------CLDVNECLQLPKACAYQCHNLQGSYRCLCPPG 3509
Query: 166 RT----GNRC---QHQAQTAA-------------PEGSVAGDSAF---SRAPRCAQVERA 202
+T G C + Q P S+ G S S P +
Sbjct: 3510 QTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSV 3569
Query: 203 QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTL 262
C GF + VC D++EC + LC HAC NT GSY+C CP GYR L
Sbjct: 3570 GRAWCPPGF----IRQNGVCTDLDECRVRN------LCQHACRNTEGSYQCLCPAGYRLL 3619
Query: 263 ADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVK-TSPFQCERN 321
GK+C+D++EC C G C NT GS+QCV CP +Y + SP C R
Sbjct: 3620 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCP-----ATYRQGPSPGTCFRR 3674
Query: 322 PCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPG 364
C D P T+ + L LP ++ + R+ S G
Sbjct: 3675 -CSQDCGTGG--PSTLQYRLLPLPLGVRAHHDVARLTAFSEVG 3714
Score = 84.3 bits (207), Expect = 2e-16
Identities = 50/152 (32%), Positives = 67/152 (44%), Gaps = 25/152 (16%)
Query: 170 RCQHQAQTAAPEG----------SVAGDSAFSRAPRCAQVERA-------QHCSCEAGFH 212
RC H Q A G + A SAF + + A C GF
Sbjct: 3283 RCNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFE 3342
Query: 213 LSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVD 272
L + C D +EC G P C HAC+N PG + CTCP G+ D ++C DVD
Sbjct: 3343 LDSQG--AFCVDRDECS-----GGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 273 ECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
EC +C +G C+N GS++C+ P+C G
Sbjct: 3396 ECAWDAHLCREGQRCVNLLGSYRCL-PDCGPG 3426
Score = 82.8 bits (203), Expect = 6e-16
Identities = 57/176 (32%), Positives = 77/176 (43%), Gaps = 21/176 (11%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR- 192
C ECS P C+ ++ C CP TG + A D+ R
Sbjct: 3350 CVDRDECSGGPSPCSHACLNAPGRFSCTCP---TGFALAWDDRNCRDVDECAWDAHLCRE 3406
Query: 193 APRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMH--ACVNTP 248
RC + + C C GF ++ AG C+DV+EC L G + C + C NTP
Sbjct: 3407 GQRCVNLLGSYRCLPDCGPGFRVADGAG---CEDVDEC-LEGLDD----CHYNQLCENTP 3458
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
G +RC+CP GYR C DV+EC+ L C C N GS++C+ CP G
Sbjct: 3459 GGHRCSCPRGYRMQGPSLPCLDVNECLQLPKAC--AYQCHNLQGSYRCL---CPPG 3509
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 111 bits (278), Expect = 1e-24
Identities = 69/244 (28%), Positives = 103/244 (42%), Gaps = 43/244 (17%)
Query: 130 EQPHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGR------------------TGN 169
E C + EC+ ++PC G CV +RC C G G
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 170 RCQHQAQTA--------------APEGSVAGD----SAFSRAPRCAQVERAQHCSCEAGF 211
C H+ + + +G D S+ + CA V + C C G+
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGY 469
Query: 212 HLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPG-GYRTLADGKSCED 270
LS G + C+D++EC L +C + C+N PGS++C+CP GYR +G++C+D
Sbjct: 470 QLSDVDGVT-CEDIDECAL---PTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Query: 271 VDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
+DECV C TC N G F+C++ ECPE + + S + P C
Sbjct: 526 IDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDC 585
Query: 331 RHLP 334
R LP
Sbjct: 586 RVLP 589
Score = 99.8 bits (247), Expect = 4e-21
Identities = 61/175 (34%), Positives = 79/175 (45%), Gaps = 27/175 (15%)
Query: 133 HCRGISECSS--QPCQNGGTCVEGVNQYRC-----ICPPG----RTGNRCQHQAQTAAPE 181
+C I+EC S PC G TC+ Y C C G G RC + A P
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 182 GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM 241
+ RC + C C+ G++ G + +C DVNEC+ Y RLC
Sbjct: 365 ------EPCGKGHRCVNSPGSFRCECKTGYYFDGIS--RMCVDVNECQRY----PGRLCG 412
Query: 242 HACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
H C NT GSY C+C G+R DG+SCED++EC P C N GS+QC
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS----SPCSQECANVYGSYQC 463
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/219 (28%), Positives = 90/219 (41%), Gaps = 35/219 (15%)
Query: 134 CRGISEC--SSQPCQNGGTCVEGVNQYRC----ICPPG---RTGNRCQHQAQTAAPEGSV 184
C ++EC S C+ G +C+ V +RC C G N C+ + + +
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNC 273
Query: 185 AGDSAFSRAPRCAQVERAQHC----SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
D C + C C++GF + A G+ C D+NEC P
Sbjct: 274 LPDFI------CQNTLGSFRCRPKLQCKSGF-IQDALGN--CIDINECLSISA---PCPI 321
Query: 241 MHACVNTPGSYRC-----TCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQ 295
H C+NT GSY C C GY +G C DVDEC C +G C+N+ GSF+
Sbjct: 322 GHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 296 CVSPECPEG--SGNVSYVKTSPFQCERNPCPMDSRPCRH 332
C EC G +S + +C+R P + C +
Sbjct: 382 C---ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCEN 417
Score = 63.9 bits (154), Expect = 3e-10
Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 19/133 (14%)
Query: 205 CSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMHACVNTPGSYRC----TCPGGY 259
CSC G+ L D V C+DVNEC R +C+NT GS+RC +C GY
Sbjct: 199 CSCFVGYQL---LSDGVSCEDVNECITGSHSCR---LGESCINTVGSFRCQRDSSCGTGY 252
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC-VSPECPEGSGNVSYVKTSPFQC 318
L + SC+D+DEC C C NT GSF+C +C G +++ + C
Sbjct: 253 E-LTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG-----FIQDALGNC 306
Query: 319 -ERNPCPMDSRPC 330
+ N C S PC
Sbjct: 307 IDINECLSISAPC 319
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 30/213 (14%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVN----QYRCIC 162
C G R+ LP T E CR + E C G++ Q RC
Sbjct: 37 CADGHRMATHQKDCSLPYAT---ESKECRMVQEQCCHSQLEELHCATGISLANEQDRCAT 93
Query: 163 PPGRTGN-------RCQHQAQT--AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHL 213
P G + RC H AA + + + +C QV RA C
Sbjct: 94 PHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRA----CCVKSQE 149
Query: 214 SGAAGDSVCQDVNEC-ELYGQEGRPRL---------CMHACVNTPGSYRCTCPGGYRTLA 263
+G Q+ ++ E+ ++ P L C C +T C+C GY+ L+
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 264 DGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
DG SCEDV+EC+ C G +CINT GSF+C
Sbjct: 210 DGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 108 bits (269), Expect = 1e-23
Identities = 87/340 (25%), Positives = 130/340 (38%), Gaps = 53/340 (15%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGR----TGNRC-----------QHQAQTA 178
C I+EC P C ++CICPPG+ G C Q+ +
Sbjct: 5313 CMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNL 5372
Query: 179 APEGSVAGD--------------SAFSR----APRCAQVERAQHCSCEAGFHLSGAAGDS 220
A V + S++S ++ R +C G A
Sbjct: 5373 ARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG----SEASHD 5428
Query: 221 VCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
C D++ECE C H C NT GSY+C CP GY+ +GK+C+D+DEC+
Sbjct: 5429 TCVDIDECE------NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVH 5482
Query: 281 CPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFH 340
C C N GS+QC+ CP N S F C +N CP + C P + +
Sbjct: 5483 CGPNRMCFNMRGSYQCIDTPCPP---NYQRDPVSGF-CLKN-CPPNDLECALSPYALEYK 5537
Query: 341 YLSLPSNLKTPITLFRMATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQ 400
+SLP + T L R+ + G P + F +V F + R + G + +
Sbjct: 5538 LVSLPFGIATNQDLIRLVAYTQDGVMHPRT-TFLMVDEEQTVPFAL-RDENLKGVVYTTR 5595
Query: 401 NLEGPQTLEVDVDMSEYLDR---SFQANHVSKVTIFVSPY 437
L +T + V S Y +Q + + + PY
Sbjct: 5596 PLREAETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY 5635
Score = 82.8 bits (203), Expect = 6e-16
Identities = 73/272 (26%), Positives = 95/272 (34%), Gaps = 56/272 (20%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISECSS-QPCQNGGTCVEGVNQYRCICPPGRT----GN 169
G S C T P C EC++ PC + +C + Y C CP G T G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSH--SCHNAMGTYYCSCPKGLTIAADGR 5143
Query: 170 RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE 229
CQ + A G C + C G + CQD+NEC
Sbjct: 5144 TCQDIDECAL------GRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC- 5196
Query: 230 LYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
QE P C C N GS+ C C GY+ G+ C DV+EC Q VC C N
Sbjct: 5197 ---QESSP--CHQRCFNAIGSFHCGCEPGYQ--LKGRKCMDVNEC--RQNVCRPDQHCKN 5247
Query: 290 TGGSFQCVSPECPEGSG--------NVSYVKTSPFQCERNP------------CP----- 324
T G ++C+ CP G ++ K QC N CP
Sbjct: 5248 TRGGYKCID-LCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS 5306
Query: 325 -------MDSRPCRHLPKTISFHYLSLPSNLK 349
MD C +PK + + P + K
Sbjct: 5307 QGVGRPCMDINECEQVPKPCAHQCSNTPGSFK 5338
Score = 80.9 bits (198), Expect = 2e-15
Identities = 64/216 (29%), Positives = 79/216 (36%), Gaps = 61/216 (28%)
Query: 134 CRGISECS--SQPCQNGGTCVEGVNQYRCI--CPPG--RTGNRCQHQAQTAAPEGSVAGD 187
C+ I EC+ C G C + YRC+ C G RT + Q E S
Sbjct: 5145 CQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ 5204
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE------------LYGQEG 235
RC + HC CE G+ L G C DVNEC G
Sbjct: 5205 -------RCFNAIGSFHCGCEPGYQLKGRK----CMDVNECRQNVCRPDQHCKNTRGGYK 5253
Query: 236 RPRLCMHA---------------------------CVNTPGSYRCTCPGGYRTLADGKSC 268
LC + C NT GSYRC CP GYR+ G+ C
Sbjct: 5254 CIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPC 5313
Query: 269 EDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
D++EC + C C NT GSF+C+ CP G
Sbjct: 5314 MDINECEQVPKPCAH--QCSNTPGSFKCI---CPPG 5344
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/171 (28%), Positives = 64/171 (37%), Gaps = 28/171 (16%)
Query: 104 HFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCI-- 161
H C PG++L G C ++EC C+ C Y+CI
Sbjct: 5214 HCGCEPGYQLKGRK----------------CMDVNECRQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 162 CPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV 221
CP G T + G C + C C G+ G
Sbjct: 5258 CPNGMTK---AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRP-- 5312
Query: 222 CQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVD 272
C D+NECE P+ C H C NTPGS++C CP G L DGKSC ++
Sbjct: 5313 CMDINECEQV-----PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLE 5358
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 107 bits (266), Expect = 3e-23
Identities = 72/237 (30%), Positives = 92/237 (38%), Gaps = 56/237 (23%)
Query: 107 CNPGFRLVGPSSV--VCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP 164
C PG + P VC P Q +C +EC PC+ G C+ V Y C C P
Sbjct: 856 CGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYP 915
Query: 165 GRT------GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAG 218
G T CQ + P G +C E + HC C+ G+ +
Sbjct: 916 GYTLATSGATQECQDINECEQPGVCSGG--------QCTNTEGSYHCECDQGYIM---VR 964
Query: 219 DSVCQDVNECE-------------------------LYGQEG---------RPRLCMHA- 243
CQD+NEC GQ G P +C H
Sbjct: 965 KGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK 1024
Query: 244 CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPE 300
C N GS+RC+C GY +D K C+DVDEC + CP G C+NT GSF C + E
Sbjct: 1025 CTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTG-LCLNTEGSFACSACE 1079
Score = 91.3 bits (225), Expect = 2e-18
Identities = 69/207 (33%), Positives = 91/207 (43%), Gaps = 28/207 (13%)
Query: 106 TCNPGFRLVGPSSVVCLP-NGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP 164
TC G + P S CL + G+ C ++EC + G C +RC C
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQ 1038
Query: 165 GRTGNRCQHQAQTAAPEGSVAGDSAFSRAP----RCAQVERAQHCS-CEAGFHLSGAAGD 219
G T+ +G D SRA C E + CS CE G+ ++
Sbjct: 1039 G--------YEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVN--EDG 1088
Query: 220 SVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCT-CPGGYRTLADGKSCEDVDECVGL 277
+ C+D++EC P +C C NT GS+ C C GGYR G SCEDVDEC
Sbjct: 1089 TACEDLDECAF------PGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDP 1142
Query: 278 QPVCPQGTTCINTGGSFQCVSPECPEG 304
Q C G C NT GS+QC+ CP+G
Sbjct: 1143 QSSC-LGGECKNTVGSYQCL---CPQG 1165
Score = 90.9 bits (224), Expect = 2e-18
Identities = 62/201 (30%), Positives = 81/201 (40%), Gaps = 26/201 (12%)
Query: 106 TCNPGFRLVGPSSVVC--LPNGTWTGEQ-PHCRGISECSSQPCQNGGTCVEGVNQYRCI- 161
+C G L S C NG W E C + EC+ G C + C
Sbjct: 1060 SCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKD 1119
Query: 162 CP----PGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA 217
C P G+ C+ + P+ S G C + C C GF L A
Sbjct: 1120 CDGGYRPSPLGDSCEDVDECEDPQSSCLGGE-------CKNTVGSYQCLCPQGFQL---A 1169
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVG 276
+VC+DVNEC G H C+N+ GS+ C C G+ + G SC+DVDEC
Sbjct: 1170 NGTVCEDVNECM-----GEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT 1224
Query: 277 LQPVCPQGTTCINTGGSFQCV 297
P G C+NT GSF C+
Sbjct: 1225 TDPCV--GGHCVNTEGSFNCL 1243
Score = 84.3 bits (207), Expect = 2e-16
Identities = 57/176 (32%), Positives = 85/176 (48%), Gaps = 22/176 (12%)
Query: 128 TGEQPHCRGISECSSQPCQNGGTCVEGVNQYRC-ICPPG----RTGNRCQHQAQTAAPEG 182
T ++ C+ + EC+S+ G C+ + C C G G C+ + A P
Sbjct: 1043 TSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102
Query: 183 SVAGDSAFSRAPRCAQVERAQHCS-CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM 241
+G C + C C+ G+ S GDS C+DV+ECE + +
Sbjct: 1103 CPSGV--------CTNTAGSFSCKDCDGGYRPS-PLGDS-CEDVDECE----DPQSSCLG 1148
Query: 242 HACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C NT GSY+C CP G++ LA+G CEDV+EC+G + P G C+N+ GSF C+
Sbjct: 1149 GECKNTVGSYQCLCPQGFQ-LANGTVCEDVNECMGEEHCAPHG-ECLNSHGSFFCL 1202
Score = 81.3 bits (199), Expect = 2e-15
Identities = 64/229 (27%), Positives = 85/229 (37%), Gaps = 57/229 (24%)
Query: 114 VGPSSVVCLPNGTWTGEQPHCRGISECSSQP-CQNGGTCVEGVNQYRCICPPG----RTG 168
VG +C P G C ++EC + C G C+ + C+C PG G
Sbjct: 1155 VGSYQCLC-PQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGG 1213
Query: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
CQ + A + V G C E + +C CE GF S +G+ C D++EC
Sbjct: 1214 TSCQDVDECATTDPCVGG--------HCVNTEGSFNCLCETGFQPSPESGE--CVDIDEC 1263
Query: 229 ELYGQ--------EGRP------------------------------RLC-MHA-CVNTP 248
E YG E P +C H C NT
Sbjct: 1264 EDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTD 1323
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
GS+RC C G+ G C DV+EC + VC C N GSF C+
Sbjct: 1324 GSFRCLCDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCL 1371
Score = 62.8 bits (151), Expect = 6e-10
Identities = 45/127 (35%), Positives = 61/127 (48%), Gaps = 12/127 (9%)
Query: 174 QAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGF-HLSGA--AGDSVCQDVNECEL 230
QA+ +G+ GD A P E ++ C G+ + GA G ++ D +EC +
Sbjct: 1433 QAECCCTQGASWGD-ACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVI 1491
Query: 231 YGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
+G P LC + C+NT Y C C G+ A K CED DEC L C G C+N
Sbjct: 1492 FG----PGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDL--ACENG-ECVN 1544
Query: 290 TGGSFQC 296
T GSF C
Sbjct: 1545 TEGSFHC 1551
Score = 56.6 bits (135), Expect = 4e-08
Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V C C GF L A C DVNEC+ G LC+H C NT GSYRC
Sbjct: 1747 RCVRVREGYTCDCFEGFQLDAA--HMACVDVNECD--DLNGPAVLCVHGYCENTEGSYRC 1802
Query: 254 TCPGGYRTLADGKSC 268
C GY A C
Sbjct: 1803 HCSPGYVAEAGPPHC 1817
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 7/61 (11%)
Query: 222 CQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
CQD+NEC G LC A CVNT GSY CTC G C LQ +
Sbjct: 620 CQDINECLTLG------LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGL 673
Query: 281 C 281
C
Sbjct: 674 C 674
Score = 38.5 bits (88), Expect = 0.012
Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 18/98 (18%)
Query: 202 AQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRT 261
A H AGF G + C +N CE GR CV Y C C G++
Sbjct: 1720 ASHPEPPAGFE--GLQAEE-CGILNGCE----NGR-------CVRVREGYTCDCFEGFQL 1765
Query: 262 LADGKSCEDVDECVGLQ---PVCPQGTTCINTGGSFQC 296
A +C DV+EC L +C G C NT GS++C
Sbjct: 1766 DAAHMACVDVNECDDLNGPAVLCVHG-YCENTEGSYRC 1802
Score = 38.1 bits (87), Expect = 0.016
Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCT 254
RC C C GFH A C+D +EC+ E CVNT GS+ C
Sbjct: 1501 RCLNTVPGYVCLCNPGFHYD--ASHKKCEDHDECQDLACENGE------CVNTEGSFHCF 1552
Query: 255 C 255
C
Sbjct: 1553 C 1553
Score = 34.7 bits (78), Expect = 0.18
Identities = 18/52 (34%), Positives = 21/52 (40%), Gaps = 5/52 (9%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQ 172
C P T HC I PCQN G+C C+C G G RC+
Sbjct: 173 CCPGWTTANSTNHC--IKPVCEPPCQNRGSC---SRPQLCVCRSGFRGARCE 219
Score = 34.3 bits (77), Expect = 0.23
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
CP GY+ L + C+D++EC+ L +C + C+NT GS+ C
Sbjct: 608 CPQGYKRL-NLTHCQDINECLTLG-LC-KDAECVNTRGSYLC 646
Score = 32.7 bits (73), Expect = 0.67
Identities = 23/104 (22%), Positives = 36/104 (34%), Gaps = 14/104 (13%)
Query: 120 VCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----GNRCQHQA 175
+C P + C EC C+NG CV + C C P T RC +
Sbjct: 1512 LCNPGFHYDASHKKCEDHDECQDLACENG-ECVNTEGSFHCFCSPPLTLDLSQQRCMNST 1570
Query: 176 QTA--APEGSVAGDSAFSRAPR--CAQVERAQ-----HCSCEAG 210
+ P+ + D + + C++ R C C+ G
Sbjct: 1571 SSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDG 1614
Score = 32.0 bits (71), Expect = 1.1
Identities = 28/113 (24%), Positives = 40/113 (35%), Gaps = 12/113 (10%)
Query: 133 HCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR 192
HC+ I+EC + CV Y C C PG + + + + + G S
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSL 678
Query: 193 APRCAQVERAQH-----CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
P + AQ C C G A S C+ +C L G E +C
Sbjct: 679 GPGTCTLPLAQRITKQICCCSR----VGKAWGSECE---KCPLPGTEAFREIC 724
Score = 30.0 bits (66), Expect = 4.3
Identities = 29/107 (27%), Positives = 38/107 (35%), Gaps = 22/107 (20%)
Query: 111 FRLVGPSSVVCLP-NGTWTGEQPHCRGISEC---SSQPCQNGGTCVEGVNQYRCICPPG- 165
F + PS +P G WT Q EC C NG C+ V Y C+C PG
Sbjct: 1459 FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGF 1517
Query: 166 ---RTGNRCQ--HQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSC 207
+ +C+ + Q A E C E + HC C
Sbjct: 1518 HYDASHKKCEDHDECQDLACENG-----------ECVNTEGSFHCFC 1553
Score = 29.3 bits (64), Expect = 7.4
Identities = 12/28 (42%), Positives = 14/28 (50%), Gaps = 3/28 (10%)
Query: 144 PCQNGGTCVEGVNQYRCICPPGRTGNRC 171
PC NGG C + + C CP TG C
Sbjct: 403 PCLNGGRC---IGRDECWCPANSTGKFC 427
Score = 29.3 bits (64), Expect = 7.4
Identities = 37/175 (21%), Positives = 59/175 (33%), Gaps = 16/175 (9%)
Query: 134 CRGISECSSQPCQNGGTCVEGVN-QYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR 192
C ++EC G E V + C+C + ++ AQ AG + S
Sbjct: 1343 CVDVNECELMLAVCGAALCENVEGSFLCLC----ASDLEEYDAQEGHCRPRGAGGQSMSE 1398
Query: 193 APRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP--RLCMHACVNTPGS 250
AP C +G + ++ + E +G C
Sbjct: 1399 APTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE 1458
Query: 251 YRCTCPGGYRTL------ADGKSC-EDVDECVGLQP-VCPQGTTCINTGGSFQCV 297
+ CP G + G++ D DECV P +CP G C+NT + C+
Sbjct: 1459 FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCL 1512
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 105 bits (263), Expect = 6e-23
Identities = 63/213 (29%), Positives = 94/213 (44%), Gaps = 43/213 (20%)
Query: 130 EQPHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGR------------------TGN 169
E C + EC+ ++PC G CV +RC C G G
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 170 RCQHQAQTA--------------APEGSVAGD----SAFSRAPRCAQVERAQHCSCEAGF 211
C H+ + + +G D S+ + CA V + C C G+
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGY 469
Query: 212 HLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPG-GYRTLADGKSCED 270
LS G + C+D++EC L +C + C+N PGS++C+CP GYR +G++C+D
Sbjct: 470 QLSDVDGVT-CEDIDECAL---PTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Query: 271 VDECVGLQPVCPQGTTCINTGGSFQCVSPECPE 303
+DECV C TC N G F+C++ ECPE
Sbjct: 526 IDECVTGIHNCSINETCFNIQGGFRCLAFECPE 558
Score = 99.8 bits (247), Expect = 4e-21
Identities = 61/175 (34%), Positives = 79/175 (45%), Gaps = 27/175 (15%)
Query: 133 HCRGISECSS--QPCQNGGTCVEGVNQYRCI-----CPPG----RTGNRCQHQAQTAAPE 181
+C I+EC S PC G TC+ Y C C G G RC + A P
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 182 GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM 241
+ RC + C C+ G++ G + +C DVNEC+ Y RLC
Sbjct: 365 ------EPCGKGHRCVNSPGSFRCECKTGYYFDGIS--RMCVDVNECQRYPG----RLCG 412
Query: 242 HACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
H C NT GSY C+C G+R DG+SCED++EC P C N GS+QC
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS----SPCSQECANVYGSYQC 463
Score = 63.9 bits (154), Expect = 3e-10
Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 19/133 (14%)
Query: 205 CSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMHACVNTPGSYRC----TCPGGY 259
CSC G+ L D V C+DVNEC R +C+NT GS+RC +C GY
Sbjct: 199 CSCFVGYQL---LSDGVSCEDVNECITGSHSCR---LGESCINTVGSFRCQRDSSCGTGY 252
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC-VSPECPEGSGNVSYVKTSPFQC 318
L + SC+D+DEC C C NT GSF+C +C G +++ + C
Sbjct: 253 E-LTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG-----FIQDALGNC 306
Query: 319 -ERNPCPMDSRPC 330
+ N C S PC
Sbjct: 307 IDINECLSISAPC 319
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 30/213 (14%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVN----QYRCIC 162
C G R+ LP T E CR + E C G++ Q RC
Sbjct: 37 CADGHRMATHQKDCSLPYAT---ESKECRMVQEQCCHSQLEELHCATGISLANEQDRCAT 93
Query: 163 PPGRTGN-------RCQHQAQT--AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHL 213
P G + RC H AA + + + +C QV RA C
Sbjct: 94 PHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRA----CCVKSQE 149
Query: 214 SGAAGDSVCQDVNEC-ELYGQEGRPRL---------CMHACVNTPGSYRCTCPGGYRTLA 263
+G Q+ ++ E+ ++ P L C C +T C+C GY+ L+
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 264 DGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
DG SCEDV+EC+ C G +CINT GSF+C
Sbjct: 210 DGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 104 bits (260), Expect = 1e-22
Identities = 67/197 (34%), Positives = 90/197 (45%), Gaps = 25/197 (12%)
Query: 133 HCRGISECSSQPCQ-NGGTCVEGVNQYRCICPPGRT----GNRCQHQAQTAAPEGSVAGD 187
+C + EC+ P GGTC Y+C CPPG G C+ + + +G
Sbjct: 1068 NCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNT 247
+C V A CSC AGF C D+NEC + Q G C C+NT
Sbjct: 1128 -------QCVNVIGAFQCSCHAGFQ--STPDRQGCVDINECRV--QNGG---CDVHCINT 1173
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGN 307
GSYRC+C GY + DG++C DVDEC VC QG C N G +C+ C +G
Sbjct: 1174 EGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCL---CYDGFMA 1229
Query: 308 VSYVKT--SPFQCERNP 322
++T +C+ NP
Sbjct: 1230 TPDMRTCVDVDECDLNP 1246
Score = 98.2 bits (243), Expect = 1e-20
Identities = 67/205 (32%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 102 EVHFTCNPGFRLVGPSSVVCLPNGTW--TGEQPHCRGISECSSQPCQNGGTCVEGVNQYR 159
E+ C+ G + S +CL + + + +Q C I EC QPC N GTC + Y
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN-GTCKNIIGSYN 1869
Query: 160 CICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGD 219
C+C PG H + R C + HC C+ GF L+ A
Sbjct: 1870 CLCFPGFV---VTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELT--ADG 1924
Query: 220 SVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQP 279
C D NEC P C N GS+RC CP G++ +D C D+DEC
Sbjct: 1925 KNCVDTNECLSLAGTCLPGTCQ----NLEGSFRCICPPGFQVQSD--HCIDIDECSEEPN 1978
Query: 280 VCPQGTTCINTGGSFQCVSPECPEG 304
+C G TC N+ GSFQC+ CP G
Sbjct: 1979 LCLFG-TCTNSPGSFQCL---CPPG 1999
Score = 97.1 bits (240), Expect = 3e-20
Identities = 64/200 (32%), Positives = 83/200 (41%), Gaps = 23/200 (11%)
Query: 104 HFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCI 161
H +C + G S CLP W G+ C + EC SQ C G C+ YRC
Sbjct: 1294 HASC---LNIPGSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCT 1348
Query: 162 CPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV 221
C G G+ + + E D+ +C C CE GF
Sbjct: 1349 CRQGFAGDGFFCEDRDECAENVDLCDNG-----QCLNAPGGYRCECEMGF--DPTEDHRA 1401
Query: 222 CQDVNECELYGQEGRPRLC-MHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
CQDV+EC + LC +C N PG +RC C GGY G +C D++EC PV
Sbjct: 1402 CQDVDEC------AQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECA--DPV 1453
Query: 281 CPQGTTCINTGGSFQCVSPE 300
CINT GS+ C P+
Sbjct: 1454 NCINGVCINTPGSYLCSCPQ 1473
Score = 97.1 bits (240), Expect = 3e-20
Identities = 66/188 (35%), Positives = 79/188 (42%), Gaps = 27/188 (14%)
Query: 124 NGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCICPPGR----TGNRCQHQAQT 177
+G G ++EC+ P C NG CV +RC CP G TG C +
Sbjct: 2072 HGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINCVDTDEC 2130
Query: 178 AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
+ G G C V C+C GF C+D++EC L P
Sbjct: 2131 SV--GHPCGQGT------CTNVIGGFECACADGFEPGLMM---TCEDIDECSL-----NP 2174
Query: 238 RLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC-PQGTTCINTGGSFQC 296
LC C NT GSY CTCP GY DG C DVDEC Q C +G C N G+F C
Sbjct: 2175 LLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFAC 2234
Query: 297 VSPECPEG 304
V CP G
Sbjct: 2235 V---CPPG 2239
Score = 95.1 bits (235), Expect = 1e-19
Identities = 56/173 (32%), Positives = 74/173 (42%), Gaps = 20/173 (11%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNR--CQHQAQTAAPEGSVAGDSAFS 191
C+ + EC+S+ CV V + C CPPG T + C + +A G
Sbjct: 2444 CKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHG--- 2500
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSY 251
C + C C GF L + C+DVNEC+ P C H C N G Y
Sbjct: 2501 ---HCHNTPGSFRCECHQGFTLVSSGHG--CEDVNECD------GPHRCQHGCQNQLGGY 2549
Query: 252 RCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
RC+CP G+ + C D +EC P C +C NT G F+CV CP G
Sbjct: 2550 RCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCV---CPSG 2598
Score = 94.7 bits (234), Expect = 1e-19
Identities = 67/235 (28%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 104 HFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNG-GTCVEGVNQYRCIC 162
H TC VG C ++ +C I EC P G GTCV + C C
Sbjct: 999 HGTCR---NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECEC 1055
Query: 163 PPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVC 222
PG + A D R C + + C C G L+ A + C
Sbjct: 1056 FPGYESGFM--LMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT--AKGTAC 1111
Query: 223 QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
+D++EC L +G LC H CVN G+++C+C G+++ D + C D++EC C
Sbjct: 1112 EDIDECSL--SDG---LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC 1166
Query: 282 PQGTTCINTGGSFQCVSPECPEGSGNV--SYVKTSPFQCERNPCPMDSRPCRHLP 334
CINT GS++C C +G + +CE NP D C ++P
Sbjct: 1167 --DVHCINTEGSYRC---SCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMP 1216
Score = 93.2 bits (230), Expect = 4e-19
Identities = 69/197 (35%), Positives = 88/197 (44%), Gaps = 18/197 (9%)
Query: 104 HFT--CNPGFRLVGPSSVVCLPNGTWTGE-QPHCRGISECSSQPCQNGGTCVEGVNQYRC 160
HFT C G L PSS C N +T + + C + EC+S PC +G CV Y C
Sbjct: 414 HFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIPGTYHC 472
Query: 161 ICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS 220
C PG + QA E V+G RC E + C C AGF LS +
Sbjct: 473 RCYPGFQATPTR-QACVDVDECIVSG--GLCHLGRCVNTEGSFQCVCNAGFELSPDGKN- 528
Query: 221 VCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQP 279
C D NEC +C++ C+N GS+ C C G+ G C D+DEC
Sbjct: 529 -CVDHNEC------ATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPG 580
Query: 280 VCPQGTTCINTGGSFQC 296
+C G C NT GSF+C
Sbjct: 581 ICVNG-HCTNTEGSFRC 596
Score = 88.6 bits (218), Expect = 1e-17
Identities = 69/254 (27%), Positives = 92/254 (36%), Gaps = 80/254 (31%)
Query: 134 CRGISECSSQ--PCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
C + EC S+ PCQ C+ YRC C G +P G+ G +
Sbjct: 1761 CEDVDECGSRESPCQQNADCINIPGSYRCKCTRG----------YKLSPGGACVGRNECR 1810
Query: 192 RAPR------CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE---------------- 229
P C E + C C GF S A ++C D++EC+
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQAS--ADQTLCMDIDECDRQPCGNGTCKNIIGSY 1868
Query: 230 ------------------------LYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADG 265
L GQ R C+NT GS+ C C G+ ADG
Sbjct: 1869 NCLCFPGFVVTHNGDCVDFDECTTLVGQVCR----FGHCLNTAGSFHCLCQDGFELTADG 1924
Query: 266 KSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPM 325
K+C D +EC+ L C G TC N GSF+C+ CP G FQ + + C +
Sbjct: 1925 KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCI---CPPG-----------FQVQSDHC-I 1968
Query: 326 DSRPCRHLPKTISF 339
D C P F
Sbjct: 1969 DIDECSEEPNLCLF 1982
Score = 85.5 bits (210), Expect = 9e-17
Identities = 75/244 (30%), Positives = 102/244 (41%), Gaps = 32/244 (13%)
Query: 107 CNPGFRLVGPSSVVC--LPNGTWTGE--QPHCRGISECSSQPCQNGGTCVEGVNQY--RC 160
C+ GF+ P+ C + G E Q CR +S SS+ C G + RC
Sbjct: 2279 CDEGFQ-PSPTLTECHDIRQGPCFAEVLQTMCRSLSS-SSEAVTRAECCCGGGRGWGPRC 2336
Query: 161 -ICP-PGRTGNR--CQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQ-----HCSCEAGF 211
+CP PG + R C H + A V D A CA E C C+AG+
Sbjct: 2337 ELCPLPGTSAYRKLCPHGSGYTAEGRDV--DECRMLAHLCAHGECINSLGSFRCHCQAGY 2394
Query: 212 HLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDV 271
A + C D++EC P+ C C NT GS+ C+CP GY DG++C+D+
Sbjct: 2395 TPDATA--TTCLDMDECSQV-----PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDL 2447
Query: 272 DECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSR-PC 330
DEC Q C C+NT G+F C CP G +C P P + C
Sbjct: 2448 DECTSRQHNCQ--FLCVNTVGAFTC---RCPPGFTQHHQACFDNDECSAQPGPCGAHGHC 2502
Query: 331 RHLP 334
+ P
Sbjct: 2503 HNTP 2506
Score = 84.3 bits (207), Expect = 2e-16
Identities = 66/203 (32%), Positives = 87/203 (42%), Gaps = 43/203 (21%)
Query: 134 CRGISECSSQP--CQNGGTCVEGVNQYRCICPPG----RTGNRC-------------QHQ 174
C ++EC S P C NG CV +RC CP G +G C + +
Sbjct: 867 CDDVNECESFPGVCPNG-RCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 175 AQTAAPE-----------GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSG-AAGDSVC 222
P G+V G P +E A C GF +G
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVEC-EACPDPESLEFASLCPRGLGFASRDFLSGRPFY 984
Query: 223 QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
+DVNEC+++ P LC H C NT GS+ C C GG+ A ++C D+DEC +C
Sbjct: 985 KDVNECKVF-----PGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLC 1039
Query: 282 PQGTTCINTGGSFQCVSPECPEG 304
QG TC+NT GSF+C EC G
Sbjct: 1040 GQG-TCVNTPGSFEC---ECFPG 1058
Score = 80.9 bits (198), Expect = 2e-15
Identities = 78/267 (29%), Positives = 104/267 (38%), Gaps = 61/267 (22%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGR-------- 166
G S C P + + C+ + EC S PC +G C Y C C PG
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTF 803
Query: 167 ----TGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERA-----QHC----SCEAGF-H 212
T C + Q + E ++ G S R+ CA + A + C +C GF
Sbjct: 804 CLDSTKGTCWLKIQESRCEVNLQGASL--RSECCATLGAAWGSPCERCEIDPACARGFAR 861
Query: 213 LSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDV 271
++G C DVNECE + P +C + CVNT GS+RC CP G A G+ C DV
Sbjct: 862 MTGVT----CDDVNECESF-----PGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDV 912
Query: 272 -----------DEC-VGLQPVCPQGTTCINTGGSF-----QCVSPE-------CPEGSGN 307
DEC V L C + G + C PE CP G G
Sbjct: 913 RLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGF 972
Query: 308 VS--YVKTSPFQCERNPCPMDSRPCRH 332
S ++ PF + N C + C H
Sbjct: 973 ASRDFLSGRPFYKDVNECKVFPGLCTH 999
Score = 80.9 bits (198), Expect = 2e-15
Identities = 58/195 (29%), Positives = 74/195 (37%), Gaps = 31/195 (15%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGT---CVEGVNQYRCICPPGRTGN 169
++G C T ++ C I+EC QNGG C+ YRC C G
Sbjct: 1132 VIGAFQCSCHAGFQSTPDRQGCVDINECR---VQNGGCDVHCINTEGSYRCSCGQG---- 1184
Query: 170 RCQHQAQTAAPEGSVAGD-SAFSRAPR------CAQVERAQHCSCEAGFHLSGAAGDSVC 222
+ P+G D PR C + C C GF C
Sbjct: 1185 ------YSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF--MATPDMRTC 1236
Query: 223 QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
DV+EC+L P +C+H C NT GS+ C C GY C DVDEC C
Sbjct: 1237 VDVDECDL-----NPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNC 1291
Query: 282 PQGTTCINTGGSFQC 296
+C+N GSF C
Sbjct: 1292 DSHASCLNIPGSFSC 1306
Score = 80.5 bits (197), Expect = 3e-15
Identities = 59/207 (28%), Positives = 82/207 (39%), Gaps = 41/207 (19%)
Query: 134 CRGISECS--SQPCQNGGTCVEGVNQYRCICPPGRTGN--------RCQHQAQTAAPEGS 183
C + EC C + +C+ + C C PG G+ C Q +P G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGD 1337
Query: 184 VAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMH 242
C V + C+C GF AGD C+D +EC LC +
Sbjct: 1338 ------------CLNVPGSYRCTCRQGF-----AGDGFFCEDRDECA-----ENVDLCDN 1375
Query: 243 A-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV---S 298
C+N PG YRC C G+ D ++C+DVDEC +C G +C N G F+C+
Sbjct: 1376 GQCLNAPGGYRCECEMGFDPTEDHRACQDVDEC-AQGNLCAFG-SCENLPGMFRCICNGG 1433
Query: 299 PECPEGSGNVSYVK--TSPFQCERNPC 323
E G GN + + P C C
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVC 1460
Score = 78.2 bits (191), Expect = 1e-14
Identities = 63/217 (29%), Positives = 88/217 (40%), Gaps = 39/217 (17%)
Query: 116 PSSVVCLPNGTWTGEQP--HCRGISECSSQPCQNGGTCVEGVNQYRCICPP----GRTGN 169
P C+ NG + ++ +C I+EC+ G C+ Y C CP +G
Sbjct: 1423 PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGV 1482
Query: 170 RC-QHQAQTAAPEGSVAGDSAFS----------RAPRCAQVERAQHCSCEAGFHLSGAAG 218
C +A E GDS S RA C + RA CE +
Sbjct: 1483 GCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEY 1542
Query: 219 DSVC---------------QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTL 262
++C +D++EC+ P LC CVNT GS++C CP GY
Sbjct: 1543 RTLCPGGEGFQPNRITVILEDIDECQEL-----PGLCQGGDCVNTFGSFQCECPPGYHLS 1597
Query: 263 ADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299
+ CED+DEC +C G TC NT G++ CV P
Sbjct: 1598 EHTRICEDIDECSTHSGICGPG-TCYNTLGNYTCVCP 1633
Score = 75.9 bits (185), Expect = 7e-14
Identities = 67/232 (28%), Positives = 92/232 (39%), Gaps = 49/232 (21%)
Query: 134 CRGISECSSQPCQNG-GTCVEGVNQYRCICPPG----RTGNRCQHQAQTAA---PEGSVA 185
C I ECS+ G GTC + Y C+CP GN C ++ G+
Sbjct: 1603 CEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQ 1662
Query: 186 GDSAFS--RAPRCAQ--VERAQHCSCEA------------------GFHLSGAAGDSVCQ 223
+ AF+ R C + +A + CEA GF G +
Sbjct: 1663 NELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPL-- 1720
Query: 224 DVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282
D++EC P +C + C+N GS+RC CP G+ + +CEDVDEC + C
Sbjct: 1721 DIDECGEI-----PAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 283 QGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQC--ERNPCPMDSRPCRH 332
Q CIN GS++C +C G K SP RN C C H
Sbjct: 1776 QNADCINIPGSYRC---KCTRG------YKLSPGGACVGRNECREIPNVCSH 1818
Score = 75.5 bits (184), Expect = 9e-14
Identities = 53/158 (33%), Positives = 70/158 (44%), Gaps = 25/158 (15%)
Query: 145 CQNGGTCVEGVNQYRCICPPGRT----GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVE 200
C NG C+ + YRC C G T G T++P GD C +
Sbjct: 419 CLNG-RCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSP--CHHGD--------CVNIP 467
Query: 201 RAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC-MHACVNTPGSYRCTCPGGY 259
HC C GF + C DV+EC + G LC + CVNT GS++C C G+
Sbjct: 468 GTYHCRCYPGFQATPTR--QACVDVDECIVSGG-----LCHLGRCVNTEGSFQCVCNAGF 520
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
DGK+C D +EC +C G C+N GSF C+
Sbjct: 521 ELSPDGKNCVDHNEC-ATSTMCVNG-VCLNEDGSFSCL 556
Score = 75.1 bits (183), Expect = 1e-13
Identities = 78/289 (26%), Positives = 108/289 (37%), Gaps = 47/289 (16%)
Query: 134 CRGISECSS-QPCQNGGTCVEGVNQYRCICPPGRTGNRCQH-QAQTAAPEGSVAGDSAFS 191
C ++EC CQ+G C + YRC CP G T QH Q E A
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFT----QHSQWAQCVDENECALSPPTC 2579
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSY 251
+ C C C +GF A G CQ+V+EC GR C ++C NTPG +
Sbjct: 2580 GSASCRNTLGGFRCVCPSGFDFDQALGG--CQEVDECA-----GRRGPCSYSCANTPGGF 2632
Query: 252 RCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYV 311
C CP GY G CV +G F + P+ +S
Sbjct: 2633 LCGCPQGYFRAGQG-------HCV--------------SGLGFSPGPQDTPDKEELLS-- 2669
Query: 312 KTSPFQCERNPCPMDSRPCR--HLPKTISFHYLSLPSNLKTPITLFRMATAS-----APG 364
+ ++C+ N RP R H ++ L + L + L + A P
Sbjct: 2670 SEACYECKINGLSPRDRPRRSAHRDHQVNLATLDSEALLTLGLNLSHLGRAERILELRPA 2729
Query: 365 RAG-PNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDV 412
G +R+ IV GN +G F M R L L + GP T ++V
Sbjct: 2730 LEGLEGRIRYVIVRGNEQGFFRMHHL-RGVSSLQLGRRRPGPGTYRLEV 2777
Score = 74.3 bits (181), Expect = 2e-13
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 36/244 (14%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCIC----PPGRTGNR 170
G S +C P +C I EC + G C +RC C G G
Sbjct: 551 GSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRV 610
Query: 171 CQHQAQTAAPEGSVAGDSAFSRAPR--------CAQVERAQHCSCEAGFHLSGAAGDSVC 222
C + G++ S P CA + C+ A ++C
Sbjct: 611 CVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALC 670
Query: 223 ----------QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDV 271
+D+NEC L P +C + C N GSYRC C GY A GK C DV
Sbjct: 671 SSGLGITTDGRDINECAL-----DPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDV 725
Query: 272 DECVGLQPVCPQGTTCINTGGSFQCVSPECPEG--SGNVSYVKTSPFQCERNPCPMDSRP 329
DEC +C G C N+ GS+ C CP G + + +C +PC S
Sbjct: 726 DECALNSLLCDNG-WCQNSPGSYSC---SCPPGFHFWQDTEICKDVDECLSSPCV--SGV 779
Query: 330 CRHL 333
CR+L
Sbjct: 780 CRNL 783
Score = 67.4 bits (163), Expect = 2e-11
Identities = 58/179 (32%), Positives = 74/179 (41%), Gaps = 36/179 (20%)
Query: 118 SVVCLPNGTWTGEQPHCRG--ISECSSQP-----CQNGGTCVEGVNQYRCICPPGRTGNR 170
SV C+ GT G C+ QP C NGG C+ G N RC C G G +
Sbjct: 121 SVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCI-GPN--RCACVYGFMGPQ 177
Query: 171 CQHQAQTAAPEGSVAGDSA--------FSRAPRCAQVERAQHCSCEA----------GFH 212
C+ +T G V + ++A CA V RA CE GF
Sbjct: 178 CERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFI 237
Query: 213 LSGAAGDSVCQDVNECELYGQEGRPRLCMH-ACVNTPGSYRCTCPGGYRTLADGKSCED 270
+ G CQDV+EC+ P LC +CVN GS+ C CP G+R +CED
Sbjct: 238 PNIHTG--ACQDVDECQAV-----PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 65.5 bits (158), Expect = 9e-11
Identities = 55/200 (27%), Positives = 76/200 (38%), Gaps = 20/200 (10%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT----G 168
++G C +G G C I ECS P C Y C CP G T G
Sbjct: 2144 VIGGFECACA-DGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 169 NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNEC 228
C+ + A + +R C + C C G +G+ C D NEC
Sbjct: 2203 AMCRDVDECADGQ-----QDCHARGMECKNLIGTFACVCPPGMRPLPGSGEG-CTDDNEC 2256
Query: 229 ELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTC 287
+P LC++ CVNT GS+RC C G++ C D+ + V T C
Sbjct: 2257 H-----AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQ--TMC 2309
Query: 288 INTGGSFQCVS-PECPEGSG 306
+ S + V+ EC G G
Sbjct: 2310 RSLSSSSEAVTRAECCCGGG 2329
Score = 57.8 bits (138), Expect = 2e-08
Identities = 59/196 (30%), Positives = 73/196 (37%), Gaps = 51/196 (26%)
Query: 132 PHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSA 189
P C G+S S S C NGGTC G + C+C G TG C G D
Sbjct: 110 PSC-GVSRGSGCSVSCMNGGTC-RGAS---CLCQKGYTGTVC----------GQPICDRG 154
Query: 190 FSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA------ 243
RC R C+C GF G +D +GQ G P C H
Sbjct: 155 CHNGGRCIGPNR---CACVYGF-----MGPQCERDYRTGPCFGQVG-PEGCQHQLTGLVC 205
Query: 244 ----CVNTPG-----------SYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCI 288
C T G + C G+ +C+DVDEC + +C QG +C+
Sbjct: 206 TKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLC-QGGSCV 264
Query: 289 NTGGSFQCVSPECPEG 304
N GSF C CP G
Sbjct: 265 NMVGSFHC---RCPVG 277
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 103 bits (258), Expect = 2e-22
Identities = 70/194 (36%), Positives = 86/194 (44%), Gaps = 32/194 (16%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVN--QYRCICPP 164
C PGFRL+ + C + CSS PC+ G TCV G + Y C CP
Sbjct: 287 CRPGFRLLD--------------DLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQ 332
Query: 165 GRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQD 224
G + +Q + DS A C C C G+ G G+ CQD
Sbjct: 333 GYQLD----SSQLDCVDVDECQDSPC--AQECVNTPGGFRCECWVGYE-PGGPGEGACQD 385
Query: 225 VNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLA-DGKSCEDVDECVGL-QPVCP 282
V+EC L GR C C NT GS+ C+C GY DG C+DVDECVG P+C
Sbjct: 386 VDECAL----GRSP-CAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC- 439
Query: 283 QGTTCINTGGSFQC 296
+ C NT GSF C
Sbjct: 440 -DSLCFNTQGSFHC 452
Score = 49.3 bits (116), Expect = 7e-06
Identities = 41/127 (32%), Positives = 48/127 (37%), Gaps = 23/127 (18%)
Query: 205 CSCEAGFHLSGAAGDSV-CQDVNECELYGQEGRPRLCMHACVNTPG--SYRCTCPGGYRT 261
C C GF L D V C N C G CV P +Y C CP GY+
Sbjct: 285 CGCRPGFRL---LDDLVTCASRNPCSSSPCRGGA-----TCVLGPHGKNYTCRCPQGYQL 336
Query: 262 LADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC-----PEGSGNVSYVKTSPF 316
+ C DVDEC P C+NT G F+C EC P G G +
Sbjct: 337 DSSQLDCVDVDECQD----SPCAQECVNTPGGFRC---ECWVGYEPGGPGEGACQDVDEC 389
Query: 317 QCERNPC 323
R+PC
Sbjct: 390 ALGRSPC 396
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCI--NTGGSFQCVSPECPEG-- 304
GS+ C C G+R L D +C + C C G TC+ G ++ C CP+G
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCVLGPHGKNYTC---RCPQGYQ 335
Query: 305 --SGNVSYVKTSPFQCERNPCPMD 326
S + V +C+ +PC +
Sbjct: 336 LDSSQLDCVDVD--ECQDSPCAQE 357
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 103 bits (257), Expect = 3e-22
Identities = 69/200 (34%), Positives = 90/200 (45%), Gaps = 30/200 (15%)
Query: 137 ISECSSQP--CQNGGTCVEGVNQYRCICPPGR----TGNRCQHQAQTAAPEGSVAGDSAF 190
++EC P C NG C+ +RC CP G TG RC + + G+ G+
Sbjct: 2172 VNECLESPGICSNG-QCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI--GNPCGNGT- 2227
Query: 191 SRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGS 250
C V + C+C GF C+D+NEC P LC C+NT GS
Sbjct: 2228 -----CTNVIGSFECNCNEGFEPGPMMN---CEDINECAQ-----NPLLCAFRCMNTFGS 2274
Query: 251 YRCTCPGGYRTLADGKSCEDVDECV-GLQPVCPQGTTCINTGGSFQCVSP----ECPEGS 305
Y CTCP GY D K C+D+DEC GL +G C N G+F C+ P P+G
Sbjct: 2275 YECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGE 2334
Query: 306 GNV--SYVKTSPFQCERNPC 323
G V + +T P CE C
Sbjct: 2335 GCVDENECRTKPGICENGRC 2354
Score = 96.3 bits (238), Expect = 5e-20
Identities = 74/230 (32%), Positives = 103/230 (44%), Gaps = 44/230 (19%)
Query: 102 EVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRG--ISECSSQP-----CQNGGTCVEG 154
++ TC G + + SV C+ GT + C+ I QP CQNGG C+ G
Sbjct: 136 QISSTC--GSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCI-G 192
Query: 155 VNQYRCICPPGRTGNRCQHQAQTAAP---------EGSVAGDSAFSRAPRCAQVERA--- 202
N RC C G TG +C+ +T +G + G ++ CA + RA
Sbjct: 193 PN--RCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTG-IVCTKTLCCATIGRAWGH 249
Query: 203 -------QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCT 254
Q C GF + G CQDV+EC+ P +C C+NT GS+ C
Sbjct: 250 PCEMCPAQPQPCRRGFIPNIRTG--ACQDVDECQAI-----PGICQGGNCINTVGSFECR 302
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
CP G++ + CED+DEC + +C G C NT GS+ CV CP G
Sbjct: 303 CPAGHKQSETTQKCEDIDECSIIPGICETG-ECSNTVGSYFCV---CPRG 348
Score = 94.4 bits (233), Expect = 2e-19
Identities = 57/187 (30%), Positives = 76/187 (40%), Gaps = 18/187 (9%)
Query: 116 PSSVVCLPNGTWTGEQPHCRGISECS--SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQH 173
P S C W G C + ECS + C CV YRC C G TG+
Sbjct: 1388 PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD---- 1443
Query: 174 QAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQ 233
T + A + +C V A C CE GF + A+ CQD++EC
Sbjct: 1444 -GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGF--TPASDSRSCQDIDECSF--- 1497
Query: 234 EGRPRLCMH-ACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGG 292
+C+ C N PG + C C GY G +C D+DEC P+ C+NT G
Sbjct: 1498 ---QNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA--DPINCVNGLCVNTPG 1552
Query: 293 SFQCVSP 299
++C P
Sbjct: 1553 RYECNCP 1559
Score = 93.2 bits (230), Expect = 4e-19
Identities = 74/242 (30%), Positives = 98/242 (40%), Gaps = 48/242 (19%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP-- 164
C PGF V PNG + C + EC + G C+ +RC CPP
Sbjct: 643 CKPGF--------VLAPNGRY------CTDVDECQTPGICMNGHCINSEGSFRCDCPPGL 688
Query: 165 --GRTGNRC--QHQAQTAAP-----------EGSVAGDSAFSRAPRCAQVERAQHCSCE- 208
G G C H T G+V P E Q C +
Sbjct: 689 AVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKN 748
Query: 209 -AGFHLSGAAGDSVC---QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLA 263
A FH ++G + +D+NEC L P +C + C N GSYRC C GY A
Sbjct: 749 SAEFHGLCSSGVGITVDGRDINECAL-----DPDICANGICENLRGSYRCNCNSGYEPDA 803
Query: 264 DGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSP--FQCERN 321
G++C D+DEC+ + +C G C NT GS+ C CP G + +T +CE N
Sbjct: 804 SGRNCIDIDECLVNRLLCDNG-LCRNTPGSYSCT---CPPGYVFRTETETCEDINECESN 859
Query: 322 PC 323
PC
Sbjct: 860 PC 861
Score = 92.0 bits (227), Expect = 9e-19
Identities = 56/199 (28%), Positives = 83/199 (41%), Gaps = 18/199 (9%)
Query: 133 HCRGISECSSQPCQ-NGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
+C I EC P GGTCV ++C CP G+ + +
Sbjct: 1155 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCP---LGHELSPSREDCVDINECSLSDNLC 1211
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSY 251
R +C + CSC G+ + C D++EC + C C N+ GSY
Sbjct: 1212 RNGKCVNMIGTYQCSCNPGYQAT--PDRQGCTDIDECMIMNGG-----CDTQCTNSEGSY 1264
Query: 252 RCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYV 311
C+C GY + DG+SC D+DEC +C G C N G ++C+ C +G +
Sbjct: 1265 ECSCSEGYALMPDGRSCADIDECENNPDIC-DGGQCTNIPGEYRCL---CYDGFMASMDM 1320
Query: 312 KTSPFQCERNPCPMDSRPC 330
KT + N C ++S C
Sbjct: 1321 KTC---IDVNECDLNSNIC 1336
Score = 91.7 bits (226), Expect = 1e-18
Identities = 63/209 (30%), Positives = 89/209 (42%), Gaps = 18/209 (8%)
Query: 130 EQPHCRGISECSSQPCQNG-GTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDS 188
E+ +C I EC P G G CV + C C G + E +
Sbjct: 1109 EERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE--CERNP 1166
Query: 189 AFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNT 247
R C E + C C G LS + D C D+NEC L LC + CVN
Sbjct: 1167 LLCRGGTCVNTEGSFQCDCPLGHELSPSRED--CVDINECSL-----SDNLCRNGKCVNM 1219
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGN 307
G+Y+C+C GY+ D + C D+DEC+ + C T C N+ GS++C C EG
Sbjct: 1220 IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCD--TQCTNSEGSYEC---SCSEGYAL 1274
Query: 308 VSYVKTSPF--QCERNPCPMDSRPCRHLP 334
+ ++ +CE NP D C ++P
Sbjct: 1275 MPDGRSCADIDECENNPDICDGGQCTNIP 1303
Score = 90.1 bits (222), Expect = 4e-18
Identities = 65/208 (31%), Positives = 88/208 (42%), Gaps = 24/208 (11%)
Query: 102 EVHFTCNPGF--RLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYR 159
E+ C+ G L G +C + +Q C + EC PC NG TC V Y
Sbjct: 1898 EIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNG-TCKNTVGSYN 1956
Query: 160 CICPPG---RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGA 216
C+C PG N C + ++ G V R RC + C C G+ L+
Sbjct: 1957 CLCYPGFELTHNNDCLDIDECSSFFGQVC------RNGRCFNEIGSFKCLCNEGYELTPD 2010
Query: 217 AGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVG 276
+ C D NEC P C N GS+RC CP GY ++ +C D++EC
Sbjct: 2011 GKN--CIDTNECVALPGSCSPGTCQ----NLEGSFRCICPPGYEVKSE--NCIDINECDE 2062
Query: 277 LQPVCPQGTTCINTGGSFQCVSPECPEG 304
+C G+ C NT G FQC+ CP G
Sbjct: 2063 DPNICLFGS-CTNTPGGFQCL---CPPG 2086
Score = 87.4 bits (215), Expect = 2e-17
Identities = 56/174 (32%), Positives = 79/174 (45%), Gaps = 22/174 (12%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPG--RTGNRCQHQAQTAAPEGSVAGDSAFS 191
C + EC+S PC NG CV Y C C G RT + Q +
Sbjct: 533 CIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRTPTK-----QACIDIDECIQNGVLC 586
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGS 250
+ RC + + C C AGF L+ + C D +EC +C++ C+N GS
Sbjct: 587 KNGRCVNTDGSFQCICNAGFELTTDGKN--CVDHDECTT------TNMCLNGMCINEDGS 638
Query: 251 YRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
++C C G+ +G+ C DVDEC +C G CIN+ GSF+C +CP G
Sbjct: 639 FKCICKPGFVLAPNGRYCTDVDEC-QTPGICMNG-HCINSEGSFRC---DCPPG 687
Score = 85.1 bits (209), Expect = 1e-16
Identities = 71/229 (31%), Positives = 96/229 (41%), Gaps = 44/229 (19%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCICPP 164
C GF+L PNG C +EC P C +G CV+ Y+CIC
Sbjct: 1878 CAAGFKLS--------PNGA-------CVDRNECLEIPNVCSHG-LCVDLQGSYQCICHN 1921
Query: 165 GRTGNRCQHQAQTAAP-EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQ 223
G ++ Q E G+ C + +C C GF L+ ++ C
Sbjct: 1922 GFKASQDQTMCMDVDECERHPCGNGT------CKNTVGSYNCLCYPGFELTH---NNDCL 1972
Query: 224 DVNECE-LYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
D++EC +GQ +C + C N GS++C C GY DGK+C D +ECV L C
Sbjct: 1973 DIDECSSFFGQ-----VCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC 2027
Query: 282 PQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
G TC N GSF+C+ CP G Y S + N C D C
Sbjct: 2028 SPG-TCQNLEGSFRCI---CPPG-----YEVKSENCIDINECDEDPNIC 2067
Score = 83.6 bits (205), Expect = 3e-16
Identities = 57/166 (34%), Positives = 73/166 (43%), Gaps = 16/166 (9%)
Query: 134 CRGISECSSQP--CQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
C I+ECS C+NG CV + Y+C C PG Q T E + +
Sbjct: 1198 CVDINECSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATP-DRQGCTDIDECMIMNGGCDT 1255
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGS 250
+ C E + CSC G+ L C D++ECE P +C C N PG
Sbjct: 1256 Q---CTNSEGSYECSCSEGYALMPDGRS--CADIDECE-----NNPDICDGGQCTNIPGE 1305
Query: 251 YRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
YRC C G+ D K+C DV+EC +C G C NT GSF C
Sbjct: 1306 YRCLCYDGFMASMDMKTCIDVNECDLNSNICMFG-ECENTKGSFIC 1350
Score = 83.2 bits (204), Expect = 4e-16
Identities = 71/218 (32%), Positives = 95/218 (43%), Gaps = 41/218 (18%)
Query: 107 CNPGFRLVGPSSVVCLPN--GTWTGE--QPHCRGISEC-----SSQPCQNGGT------- 150
CN GF+ S CL N G E Q C+ S S+ C +GG
Sbjct: 2365 CNEGFQS-SSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCE 2423
Query: 151 -C-VEGVNQYRCICP--PGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCS 206
C + G QY+ ICP PG T + P G +C + C
Sbjct: 2424 LCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG--------QCINTMGSFRCF 2475
Query: 207 CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGK 266
C+ G+ + +G S C D++EC P+ C + C NT GSY+C+CP GY DGK
Sbjct: 2476 CKVGY-TTDISGTS-CIDLDECSQ-----SPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
Query: 267 SCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
+C+D+DEC Q C C+NT G F C +CP G
Sbjct: 2529 TCKDLDECQTKQHNCQ--FLCVNTLGGFTC---KCPPG 2561
Score = 82.8 bits (203), Expect = 6e-16
Identities = 58/201 (28%), Positives = 83/201 (41%), Gaps = 29/201 (14%)
Query: 134 CRGISECS--SQPCQNGGTCVEGVNQYRCICPPGRTGN--RCQHQAQTAAPEGSVAGDSA 189
C + EC + C +C+ ++C C G GN +C + + G
Sbjct: 1365 CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSN------GTHQ 1418
Query: 190 FSRAPRCAQVERAQHCSCEAGFHLSGAAGDS-VCQDVNECELYGQEGRPRLCMHA-CVNT 247
S +C + C+C GF GD C DV+EC LC + C+N
Sbjct: 1419 CSINAQCVNTPGSYRCACSEGF-----TGDGFTCSDVDECA-----ENINLCENGQCLNV 1468
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP---ECPEG 304
PG+YRC C G+ +D +SC+D+DEC Q +C G TC N G F C+ E
Sbjct: 1469 PGAYRCECEMGFTPASDSRSCQDIDEC-SFQNICVFG-TCNNLPGMFHCICDDGYELDRT 1526
Query: 305 SGNVSYVK--TSPFQCERNPC 323
GN + + P C C
Sbjct: 1527 GGNCTDIDECADPINCVNGLC 1547
Score = 81.6 bits (200), Expect = 1e-15
Identities = 64/225 (28%), Positives = 93/225 (41%), Gaps = 40/225 (17%)
Query: 106 TCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP- 164
TCN L G +C +C I EC+ G CV +Y C CPP
Sbjct: 1505 TCN---NLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPD 1561
Query: 165 --------GRTGNRCQHQAQTAAP--EGSVAGDSAF----SRAPRCAQVERAQHCSCEAG 210
G NR + P +GS++ ++ SR+ C + +A CE
Sbjct: 1562 FQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETC 1621
Query: 211 FHLSGAAGDSVC---------------QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCT 254
++ ++C +D++EC+ P LC C+NT GS++C
Sbjct: 1622 PPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQEL-----PGLCQGGNCINTFGSFQCE 1676
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299
CP GY D + CED+DEC VC G TC NT G++ C+ P
Sbjct: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCICP 1720
Score = 78.6 bits (192), Expect = 1e-14
Identities = 54/158 (34%), Positives = 71/158 (44%), Gaps = 25/158 (15%)
Query: 145 CQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVE 200
C NG C+ V+ YRC C G G+ T+ P GD C
Sbjct: 505 CLNG-RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP--CTNGD--------CVNTP 553
Query: 201 RAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGY 259
+ +C C AGF + C D++EC G LC + CVNT GS++C C G+
Sbjct: 554 GSYYCKCHAGFQRTPTK--QACIDIDECIQNGV-----LCKNGRCVNTDGSFQCICNAGF 606
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
DGK+C D DEC +C G CIN GSF+C+
Sbjct: 607 ELTTDGKNCVDHDECTTTN-MCLNG-MCINEDGSFKCI 642
Score = 78.6 bits (192), Expect = 1e-14
Identities = 57/196 (29%), Positives = 72/196 (36%), Gaps = 20/196 (10%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGT---CVEGVNQYRCICPPGRTGN 169
++G C P T ++ C I EC NGG C Y C C G
Sbjct: 1219 MIGTYQCSCNPGYQATPDRQGCTDIDECM---IMNGGCDTQCTNSEGSYECSCSEGYA-- 1273
Query: 170 RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE 229
++ A + +C + C C GF S C DVNEC+
Sbjct: 1274 -LMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMAS--MDMKTCIDVNECD 1330
Query: 230 LYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCI 288
L +CM C NT GS+ C C GY C DVDEC C +C+
Sbjct: 1331 L-----NSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
Query: 289 NTGGSFQCVSPECPEG 304
N GSF+C C EG
Sbjct: 1386 NIPGSFKC---SCREG 1398
Score = 78.2 bits (191), Expect = 1e-14
Identities = 64/224 (28%), Positives = 89/224 (39%), Gaps = 45/224 (20%)
Query: 134 CRGISECSSQP--CQNGGTCVEGVNQYRCICPPGRT---------------------GNR 170
C ++EC P C NG CV + C CP G T +
Sbjct: 953 CEDVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDE 1011
Query: 171 CQH------QAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSG--AAGDSVC 222
C H + A + P+ E C AGF G G
Sbjct: 1012 CIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFY 1071
Query: 223 QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
+D+NEC+ + P +C + C NT GS++C C G+ + ++C D+DEC +C
Sbjct: 1072 KDINECKAF-----PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC 1126
Query: 282 PQGTTCINTGGSFQCVSPECPEG--SGNVSYVKTSPF-QCERNP 322
G C+NT GSF+C EC EG SG + +CERNP
Sbjct: 1127 GSG-ICVNTPGSFEC---ECFEGYESGFMMMKNCMDIDECERNP 1166
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/186 (31%), Positives = 81/186 (43%), Gaps = 23/186 (12%)
Query: 154 GVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDS----AFSRAPRCAQVERAQHCSCEA 209
G +Y +CP G G + T P + +C + C C +
Sbjct: 1044 GTKEYETLCPRG-AGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNS 1102
Query: 210 GFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRT-LADGKS 267
GF L + C D++EC + P LC CVNTPGS+ C C GY + K+
Sbjct: 1103 GFALD--MEERNCTDIDECRI-----SPDLCGSGICVNTPGSFECECFEGYESGFMMMKN 1155
Query: 268 CEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQC-ERNPCPMD 326
C D+DEC P+ +G TC+NT GSFQC +CP G + S C + N C +
Sbjct: 1156 CMDIDEC-ERNPLLCRGGTCVNTEGSFQC---DCPLG----HELSPSREDCVDINECSLS 1207
Query: 327 SRPCRH 332
CR+
Sbjct: 1208 DNLCRN 1213
Score = 76.6 bits (187), Expect = 4e-14
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 55/249 (22%)
Query: 123 PNGTWTGEQPH-CRGISECSSQPCQNG-GTCVEGVNQYRCICPPG----RTGNRCQHQAQ 176
P G + E C I EC + P G GTC + Y CICPP G+ C +
Sbjct: 1678 PQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRK 1737
Query: 177 TAAPEGSVAGDSAFSRAP------RCA---QVERAQHCSCEA-----------------G 210
+ S G + + P C V +A + CE G
Sbjct: 1738 SFCYR-SYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPG 1796
Query: 211 FHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCE 269
F G +V D++EC+ P +C + C+N GS+RC CP G+ CE
Sbjct: 1797 FTFDIHTGKAV--DIDECKEI-----PGICANGVCINQIGSFRCECPTGFSYNDLLLVCE 1849
Query: 270 DVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRP 329
D+DEC +C + CIN+ GS++C EC G F+ N +D
Sbjct: 1850 DIDECSNGDNLCQRNADCINSPGSYRC---ECAAG-----------FKLSPNGACVDRNE 1895
Query: 330 CRHLPKTIS 338
C +P S
Sbjct: 1896 CLEIPNVCS 1904
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/221 (28%), Positives = 86/221 (38%), Gaps = 41/221 (18%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGR----TG-- 168
G S C P + E C I+EC S PC NG C + + C C PG TG
Sbjct: 831 GSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLI 889
Query: 169 ------NRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSV- 221
C Q + E ++ G + S CA + A CE L A +
Sbjct: 890 CIDSLKGTCWLNIQDSRCEVNINGATLKSEC--CATLGAAWGSPCER-CELDTACPRGLA 946
Query: 222 ------CQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDV--- 271
C+DVNECE++ P +C + CVN+ GS+ C CP G G+ C D+
Sbjct: 947 RIKGVTCEDVNECEVF-----PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
Query: 272 --------DECVGLQP-VCPQGTTCINTGGSFQCVSPECPE 303
DEC+ P C G ++ ECP+
Sbjct: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPK 1042
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/178 (30%), Positives = 77/178 (43%), Gaps = 27/178 (15%)
Query: 134 CRGISECS-SQPCQNGGTCVEGVNQYRCIC----PPGRTGNRCQHQAQTAAPEGSVAGDS 188
C ECS PC NG TC + + C C PG N C+ + A +
Sbjct: 2211 CVDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMN-CEDINECA--------QN 2260
Query: 189 AFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE--LYGQEGRPRLCMHACVN 246
A RC + C+C G+ L +C+D++EC L+ E R +C N
Sbjct: 2261 PLLCAFRCMNTFGSYECTCPIGYAL--REDQKMCKDLDECAEGLHDCESRGMMCK----N 2314
Query: 247 TPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
G++ C CP G DG+ C D +EC +C G C+N GS++C EC EG
Sbjct: 2315 LIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENG-RCVNIIGSYRC---ECNEG 2368
Score = 73.6 bits (179), Expect = 3e-13
Identities = 65/243 (26%), Positives = 83/243 (34%), Gaps = 67/243 (27%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSVAGDSA 189
C + ECS P C Y+C CP G G C+ + + +
Sbjct: 2489 CIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--- 2545
Query: 190 FSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC--MHACVNT 247
C C C GF A C D NEC +P LC C NT
Sbjct: 2546 -----LCVNTLGGFTCKCPPGFTQHHTA----CIDNNECG-----SQPSLCGAKGICQNT 2591
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDEC--------------VGLQPVCPQG--------- 284
PGS+ C C G+ A G +CEDVDEC G + CPQG
Sbjct: 2592 PGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQ 2651
Query: 285 ---------------TTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRP 329
+C NT GS++C CP G S+ + S + N C P
Sbjct: 2652 CVDENECSNPNACGSASCYNTLGSYKCA---CPSG---FSFDQFSSACHDVNECSSSKNP 2705
Query: 330 CRH 332
C +
Sbjct: 2706 CNY 2708
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/208 (27%), Positives = 77/208 (37%), Gaps = 50/208 (24%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGD--SAFS 191
C+ + EC ++ CV + + C CPPG T Q TA + + G S
Sbjct: 2530 CKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT------QHHTACIDNNECGSQPSLCG 2583
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE------------LYGQE----- 234
C + C C+ GF L + C+DV+EC+ L G
Sbjct: 2584 AKGICQNTPGSFSCECQRGFSLDATGLN--CEDVDECDGNHRCQHGCQNILGGYRCGCPQ 2641
Query: 235 -----------------GRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVG 276
P C A C NT GSY+C CP G+ +C DV+EC
Sbjct: 2642 GYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSS 2701
Query: 277 LQPVCPQGTTCINTGGSFQCVSPECPEG 304
+ C G C NT G + C CP G
Sbjct: 2702 SKNPCNYG--CSNTEGGYLC---GCPPG 2724
Score = 72.4 bits (176), Expect = 8e-13
Identities = 48/165 (29%), Positives = 72/165 (43%), Gaps = 26/165 (15%)
Query: 114 VGPSSVVCLPNGTWTGEQPHCRGISECSS---QPCQNGGTCVEGVNQYRCICPPGRT--- 167
VG + +C P T C I ECSS Q C+NG C + ++C+C G
Sbjct: 1952 VGSYNCLCYPGFELTHNND-CLDIDECSSFFGQVCRNG-RCFNEIGSFKCLCNEGYELTP 2009
Query: 168 -GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVN 226
G C + A GS + + C +E + C C G+ + C D+N
Sbjct: 2010 DGKNCIDTNECVALPGSCSPGT-------CQNLEGSFRCICPPGYEVKSEN----CIDIN 2058
Query: 227 ECELYGQEGRPRLCMH-ACVNTPGSYRCTCPGGYRTLADGKSCED 270
EC+ P +C+ +C NTPG ++C CP G+ +G+ C D
Sbjct: 2059 ECD-----EDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Score = 72.0 bits (175), Expect = 1e-12
Identities = 66/217 (30%), Positives = 78/217 (35%), Gaps = 45/217 (20%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQ 176
C T + C+ I ECS Q GTC + CIC G RTG C +
Sbjct: 1476 CEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDE 1535
Query: 177 TAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECEL-YGQEG 235
A P V G C C+C F L+ V V C L +G G
Sbjct: 1536 CADPINCVNG--------LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRG 1587
Query: 236 ---------------RPRLCM-------HACVNTPG----SYRCTCPGG--YRTLADGKS 267
R C + C P Y CPGG +R
Sbjct: 1588 DGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITII 1647
Query: 268 CEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
ED+DEC L +C QG CINT GSFQC ECP+G
Sbjct: 1648 LEDIDECQELPGLC-QGGNCINTFGSFQC---ECPQG 1680
Score = 70.1 bits (170), Expect = 4e-12
Identities = 70/238 (29%), Positives = 91/238 (38%), Gaps = 56/238 (23%)
Query: 82 PALNTPADGRKFGSKYLVDHEVHFTCNPGFR---LVGP------SSVVCLPNGTWTGEQP 132
P L DGR VD + TC G + V P S C N + +P
Sbjct: 686 PGLAVGMDGR-----VCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEP 740
Query: 133 HCRGISECSSQPCQNG----GTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDS 188
C P +N G C GV I GR N C A D
Sbjct: 741 -------CQPCPAKNSAEFHGLCSSGVG----ITVDGRDINEC-------------ALDP 776
Query: 189 AFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNT 247
C + + C+C +G+ + + C D++EC + LC + C NT
Sbjct: 777 DICANGICENLRGSYRCNCNSGYEPDASGRN--CIDIDECLV-----NRLLCDNGLCRNT 829
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
PGSY CTCP GY + ++CED++EC C G C N GSF C EC GS
Sbjct: 830 PGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNG-ACRNNLGSFNC---ECSPGS 881
Score = 65.1 bits (157), Expect = 1e-10
Identities = 53/201 (26%), Positives = 76/201 (37%), Gaps = 23/201 (11%)
Query: 129 GEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDS 188
G +C I+EC+ P C+ Y C CP G Q + E +
Sbjct: 2246 GPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDL-DECAEGLHD 2304
Query: 189 AFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNT 247
SR C + C C G ++ C D NEC +P +C + CVN
Sbjct: 2305 CESRGMMCKNLIGTFMCICPPG--MARRPDGEGCVDENECRT-----KPGICENGRCVNI 2357
Query: 248 PGSYRCTCPGGYRTLADGKSCEDVDE--CVG--LQPVCPQGTTCINTGGSFQCVSPECPE 303
GSYRC C G+++ + G C D + C LQ +C ++ N +C C +
Sbjct: 2358 IGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSEC----CCD 2413
Query: 304 GSGNVSYVKTSPFQCERNPCP 324
G + QCE P P
Sbjct: 2414 GGRGWGH------QCELCPLP 2428
Score = 63.9 bits (154), Expect = 3e-10
Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 133 HCRGISECS-SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
+C + EC + CQ+G C + YRC CP G + +Q E + +A
Sbjct: 2611 NCEDVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQH---YQWNQCVDENECSNPNACG 2665
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSY 251
A C + C+C +GF + S C DVNEC C + C NT G Y
Sbjct: 2666 SAS-CYNTLGSYKCACPSGFSFDQFS--SACHDVNECS-----SSKNPCNYGCSNTEGGY 2717
Query: 252 RCTCPGGYRTLADG 265
C CP GY + G
Sbjct: 2718 LCGCPPGYYRVGQG 2731
Score = 58.5 bits (140), Expect = 1e-08
Identities = 60/231 (25%), Positives = 89/231 (38%), Gaps = 46/231 (19%)
Query: 106 TCNPGF--RLVGPSSVVCLPNGTWTGEQPHCRGISECSSQP--CQNGGTCVEGVNQYRCI 161
+C+PG L G +C P + + +C I+EC P C G +C ++C+
Sbjct: 2026 SCSPGTCQNLEGSFRCICPPG--YEVKSENCIDINECDEDPNICLFG-SCTNTPGGFQCL 2082
Query: 162 CPPG----RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA 217
CPPG G RC Q+ G + P+ +A+ C
Sbjct: 2083 CPPGFVLSDNGRRCFDTRQSFCFTNFENGKCS---VPKAFNTTKAKCC------------ 2127
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLAD-GKSCEDVDECVG 276
C EG C + +++ CP G+ T+ + EDV+EC+
Sbjct: 2128 ----------CSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLE 2177
Query: 277 LQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCER----NPC 323
+C G CINT GSF+C ECP G N+ Y + NPC
Sbjct: 2178 SPGICSNG-QCINTDGSFRC---ECPMGY-NLDYTGVRCVDTDECSIGNPC 2223
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 102 bits (255), Expect = 5e-22
Identities = 65/192 (33%), Positives = 83/192 (43%), Gaps = 18/192 (9%)
Query: 114 VGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQH 173
VG +C +Q C I+EC C NG TC + + C C G H
Sbjct: 1869 VGSFYCLCHTGFKTNDDQTMCLDINECERDACGNG-TCRNTIGSFNCRCNHGFI---LSH 1924
Query: 174 QAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQ 233
+ +G+ R +C + C C G+ + A C D+NEC L
Sbjct: 1925 NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEV--APDGRTCVDINECLL--- 1979
Query: 234 EGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGG 292
PR C C N GSYRC CP GY + CED+DECV +C G TC NT G
Sbjct: 1980 --EPRKCAPGTCQNLDGSYRCICPPGYSL--QNEKCEDIDECVEEPEICALG-TCSNTEG 2034
Query: 293 SFQCVSPECPEG 304
SF+C+ CPEG
Sbjct: 2035 SFKCL---CPEG 2043
Score = 99.0 bits (245), Expect = 8e-21
Identities = 61/208 (29%), Positives = 95/208 (45%), Gaps = 27/208 (12%)
Query: 103 VHFTCNPGFRLVGPSSVVCLPN-GTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCI 161
V + C G + P S C N G + C + EC PC GG C+ Y C
Sbjct: 456 VRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQ 514
Query: 162 CPPGR----TGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA 217
C G T C+ G + + RC + + HC C AGFH++
Sbjct: 515 CRAGYQSTLTRTECR-DIDECLQNGRICNNG------RCINTDGSFHCVCNAGFHVTRDG 567
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVG 276
+ C+D++EC + +C++ C+N GS++C C G++ +DG+ C+D++EC
Sbjct: 568 KN--CEDMDECSIRN------MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-E 618
Query: 277 LQPVCPQGTTCINTGGSFQCVSPECPEG 304
+C G C+NT GS++C EC G
Sbjct: 619 TPGICMNG-RCVNTDGSYRC---ECFPG 642
Score = 91.7 bits (226), Expect = 1e-18
Identities = 64/209 (30%), Positives = 83/209 (39%), Gaps = 25/209 (11%)
Query: 124 NGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGR--TGNRCQHQAQTAAPE 181
+G G + EC G C+ YRC CP G GN C + +
Sbjct: 2115 SGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSV-- 2172
Query: 182 GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM 241
G+ G+ C V C+CE GF C+D+NEC P LC
Sbjct: 2173 GNPCGNGT------CKNVIGGFECTCEEGFEPGPMM---TCEDINECAQ-----NPLLCA 2218
Query: 242 HACVNTPGSYRCTCPGGYRTLADGKSCEDVDEC-VGLQPVCPQGTTCINTGGSFQCVS-- 298
CVNT GSY C CP GY D + C+D DEC G + C N G++ C+
Sbjct: 2219 FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGP 2278
Query: 299 --PECPEGSGNV--SYVKTSPFQCERNPC 323
P+G G V + +T P CE C
Sbjct: 2279 GYQRRPDGEGCVDENECQTKPGICENGRC 2307
Score = 89.0 bits (219), Expect = 8e-18
Identities = 62/221 (28%), Positives = 86/221 (38%), Gaps = 37/221 (16%)
Query: 133 HCRGISECSSQPCQ-NGGTCVEGVNQYRCICPPGRTG----------NRCQHQAQTAAPE 181
+C I EC P GG C YRC CPPG N C+ A P
Sbjct: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLC-PN 1168
Query: 182 GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM 241
G RC + C+C G+H C D++EC + C
Sbjct: 1169 G------------RCVNLIGKYQCACNPGYH--STPDRLFCVDIDECSIMNGG-----CE 1209
Query: 242 HACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC 301
C N+ GSY C+C G+ + D +SC D+DEC +C G C N G ++C+ C
Sbjct: 1210 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPGEYRCL---C 1265
Query: 302 PEGSGNVSYVKT--SPFQCERNPCPMDSRPCRHLPKTISFH 340
+G +KT +C+ NP S C + + H
Sbjct: 1266 YDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICH 1306
Score = 88.6 bits (218), Expect = 1e-17
Identities = 71/243 (29%), Positives = 94/243 (38%), Gaps = 44/243 (18%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGR 166
CN GF P+ CL N + +C +E CQ G + V + C C GR
Sbjct: 2318 CNDGFT-ASPNQDECLDN-----REGYC--FTEVLQNMCQIGSSNRNPVTKSECCCDGGR 2369
Query: 167 TGNR----CQHQAQTAAPEGSVAGDSAFS---------------RAPRCAQVERAQHCSC 207
C Q A + G + R C + HC C
Sbjct: 2370 GWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCIC 2429
Query: 208 EAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKS 267
+ G+ G S C D+NEC P+ C C NT GSY+C+CP GY DG+S
Sbjct: 2430 KTGY-TPDITGTS-CVDLNECNQ-----APKPCNFICKNTEGSYQCSCPKGYILQEDGRS 2482
Query: 268 CEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDS 327
C+D+DEC Q C C+NT G F C +CP G + + + N C D
Sbjct: 2483 CKDLDECATKQHNCQ--FLCVNTIGGFTC---KCPPG-----FTQHHTSCIDNNECTSDI 2532
Query: 328 RPC 330
C
Sbjct: 2533 NLC 2535
Score = 88.2 bits (217), Expect = 1e-17
Identities = 70/265 (26%), Positives = 102/265 (38%), Gaps = 57/265 (21%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGT---CVEGVNQYRCICPPGRT-- 167
L+G C P T ++ C I ECS NGG C Y C C PG
Sbjct: 1174 LIGKYQCACNPGYHSTPDRLFCVDIDECS---IMNGGCETFCTNSEGSYECSCQPGFALM 1230
Query: 168 --------------------GNRCQH---QAQTAAPEGSVAGDSA--------------F 190
G +C + + + +G +A +
Sbjct: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNI 1290
Query: 191 SRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPG 249
+ C + + C C+ G+ SG G + C D+NECE+ G HA C NT G
Sbjct: 1291 CLSGTCENTKGSFICHCDMGY--SGKKGKTGCTDINECEI----GAHNCGKHAVCTNTAG 1344
Query: 250 SYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVS 309
S++C+C G+ + DG C D+DEC +C Q C NT GS++C+ C EG
Sbjct: 1345 SFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL---CKEGYTGDG 1399
Query: 310 YVKTSPFQCERNPCPMDSRPCRHLP 334
+ T +C N + C + P
Sbjct: 1400 FTCTDLDECSENLNLCGNGQCLNAP 1424
Score = 87.8 bits (216), Expect = 2e-17
Identities = 68/222 (30%), Positives = 98/222 (44%), Gaps = 42/222 (18%)
Query: 110 GFRLVGPSSVVCLPNGTWTGEQPHCRG--ISECSSQP-----CQNGGTCVEGVNQYRCIC 162
G R + ++ C+ G+ + + C+ I QP C NGG CV RC C
Sbjct: 112 GSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVA---PNRCAC 168
Query: 163 PPGRTGNRCQHQAQTAAP---------EGSVAGDSAFSRAPRCAQVERA----------Q 203
G TG +C+ +T +G ++G ++ CA V RA Q
Sbjct: 169 TYGFTGPQCERDYRTGPCFTVISNQMCQGQLSG-IVCTKTLCCATVGRAWGHPCEMCPAQ 227
Query: 204 HCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTL 262
C GF + G CQDV+EC+ P LC C+NT GS+ C CP G++
Sbjct: 228 PHPCRRGFIPNIRTG--ACQDVDECQAI-----PGLCQGGNCINTVGSFECKCPAGHKLN 280
Query: 263 ADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
+ CED+DEC + +C +G C NT S+ C +CP G
Sbjct: 281 EVSQKCEDIDECSTIPGIC-EGGECTNTVSSYFC---KCPPG 318
Score = 87.8 bits (216), Expect = 2e-17
Identities = 70/243 (28%), Positives = 94/243 (38%), Gaps = 51/243 (20%)
Query: 102 EVHFTCNPG--FRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQP-CQNGGTCVEGVNQY 158
E+ C G +VG C + + C I EC + P CQ C+ Y
Sbjct: 1772 EIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSY 1831
Query: 159 RCICPPG----RTG-----NRCQH------QAQTAAPEGSV-----AGDSAFSRAPRCAQ 198
RC C PG TG N CQ Q GS G C
Sbjct: 1832 RCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD 1891
Query: 199 VERAQ----------------HCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMH 242
+ + +C C GF LS ++ C DV+EC G LC +
Sbjct: 1892 INECERDACGNGTCRNTIGSFNCRCNHGFILSH---NNDCIDVDECA----SGNGNLCRN 1944
Query: 243 A-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC 301
C+NT GS++C C GY DG++C D++EC+ C G TC N GS++C+ C
Sbjct: 1945 GQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG-TCQNLDGSYRCI---C 2000
Query: 302 PEG 304
P G
Sbjct: 2001 PPG 2003
Score = 86.3 bits (212), Expect = 5e-17
Identities = 72/245 (29%), Positives = 98/245 (40%), Gaps = 51/245 (20%)
Query: 123 PNGTWTGEQPH-CRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQT 177
P G + E C ++EC + GTC V Y CICPP GN C ++
Sbjct: 1634 PTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRS 1693
Query: 178 A------APEGSVAGDSAFSRAPRCA----QVERAQHCSCE------------------A 209
A + G+ F+ + + RA + CE
Sbjct: 1694 LCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRP 1753
Query: 210 GFHLSGAAGDSVCQDVNECELYGQEGRPRLCMH-ACVNTPGSYRCTCPGGYRTLADGKSC 268
GF + G V D++EC P +C + C+N GS+RC CP G+ C
Sbjct: 1754 GFVIDIYTGLPV--DIDECREI-----PGVCENGVCINMVGSFRCECPVGFFYNDKLLVC 1806
Query: 269 EDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQC-ERNPCPMDS 327
ED+DEC PVC + CINT GS++C +C G Y TS QC +RN C
Sbjct: 1807 EDIDECQN-GPVCQRNAECINTAGSYRC---DCKPG-----YRFTSTGQCNDRNECQEIP 1857
Query: 328 RPCRH 332
C H
Sbjct: 1858 NICSH 1862
Score = 84.7 bits (208), Expect = 1e-16
Identities = 68/234 (29%), Positives = 97/234 (41%), Gaps = 36/234 (15%)
Query: 108 NPGFRLVGP-----SSVVCLPNGTWTGEQPH--CRGISECS--SQPCQNGGTCVEGVNQY 158
NP L G S +C + ++G++ C I+EC + C C +
Sbjct: 1287 NPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSF 1346
Query: 159 RCICPPGRTGN--RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGA 216
+C C PG G+ +C + + G S+ C + C C+ G+
Sbjct: 1347 KCSCSPGWIGDGIKCTDLDECSN------GTHMCSQHADCKNTMGSYRCLCKEGY----- 1395
Query: 217 AGDS-VCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDEC 274
GD C D++EC LC + C+N PG YRC C G+ ADGK+CED+DEC
Sbjct: 1396 TGDGFTCTDLDECS-----ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC 1450
Query: 275 VGLQPVCPQGTTCINTGGSFQC---VSPECPEGSGNVSYVK--TSPFQCERNPC 323
L +C G TC N G F+C + E GN + V P C C
Sbjct: 1451 -SLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNC 1502
Score = 77.4 bits (189), Expect = 2e-14
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 45/224 (20%)
Query: 134 CRGISECSSQP--CQNGGTCVEGVNQYRCICPPG----RTGNRC---------------- 171
C I EC P C+NG CV ++C CP G TG C
Sbjct: 908 CEDIDECEVFPGVCKNG-LCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEE 966
Query: 172 -------QHQAQT-AAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAA-GDSVC 222
+H+ G+ G P E + C GF G
Sbjct: 967 CTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFF 1026
Query: 223 QDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
+D+NEC++ P LC H C NT GS++C C G+ ++ ++C D+DEC +C
Sbjct: 1027 KDINECKMI-----PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC 1081
Query: 282 PQGTTCINTGGSFQCVSPECPEG--SGNVSYVKTSPF-QCERNP 322
+G C+NT G F+C +C EG SG + +C+R+P
Sbjct: 1082 GRG-QCVNTPGDFEC---KCDEGYESGFMMMKNCMDIDECQRDP 1121
Score = 75.5 bits (184), Expect = 9e-14
Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 34/173 (19%)
Query: 134 CRGISEC--SSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTAAPEGSVAGD 187
CR I EC + + C NG C+ + C+C G R G C+ + + + G
Sbjct: 528 CRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNG- 585
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVN 246
C + + C C+ GF L A+ C+D+NECE P +CM+ CVN
Sbjct: 586 -------MCINEDGSFKCICKPGFQL--ASDGRYCKDINECET------PGICMNGRCVN 630
Query: 247 TPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSP 299
T GSYRC C G DG+ C D +TC QC+ P
Sbjct: 631 TDGSYRCECFPGLAVGLDGRVCVDTH----------MRSTCYGGYKRGQCIKP 673
Score = 74.7 bits (182), Expect = 2e-13
Identities = 55/200 (27%), Positives = 83/200 (41%), Gaps = 41/200 (20%)
Query: 133 HCRGISECSSQPCQNGGTCVEGVNQYRCICPPG-------------RTGNRCQHQAQTAA 179
+C ++EC G CV Y C CPP R+GN C +
Sbjct: 1484 NCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN-CYLDIRPRG 1542
Query: 180 PEGSVAGDSAF----SRAPRCAQVERAQHCSCE-------AGFHLSGAAGDS-------- 220
G A + S+A C + +A CE + + + G+
Sbjct: 1543 DNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITV 1602
Query: 221 VCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQP 279
+ +D++EC+ P LC C+NT GS++C CP GY D + C+DV+EC
Sbjct: 1603 ILEDIDECQEL-----PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPG 1656
Query: 280 VCPQGTTCINTGGSFQCVSP 299
+C G TC NT G++ C+ P
Sbjct: 1657 ICGPG-TCYNTVGNYTCICP 1675
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 33/211 (15%)
Query: 103 VHFTCNPGFRLVGPSSVVCLPNGTWTGE--QPHCRGISECSSQPCQNGGTCVEGVNQYRC 160
+H C G + S C+ +T + C ++EC+ P C Y+C
Sbjct: 2409 IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQC 2468
Query: 161 ICPPG----RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGF---HL 213
CP G G C+ + A + + C C C GF H
Sbjct: 2469 SCPKGYILQEDGRSCKDLDECATKQHNCQF--------LCVNTIGGFTCKCPPGFTQHHT 2520
Query: 214 SGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDE 273
S + D+N C G +G C NTPGS+ C C G+ G SCEDVDE
Sbjct: 2521 SCIDNNECTSDINLC---GSKG-------ICQNTPGSFTCECQRGFSLDQTGSSCEDVDE 2570
Query: 274 CVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
C G C G C N G ++C CP+G
Sbjct: 2571 CEG-NHRCQHG--CQNIIGGYRC---SCPQG 2595
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/206 (26%), Positives = 77/206 (37%), Gaps = 46/206 (22%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRA 193
C+ + EC+++ CV + + C CPPG T QH + +
Sbjct: 2483 CKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT----QHHTSCIDNNECTSDINLCGSK 2538
Query: 194 PRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECEL----------------------Y 231
C + C C+ GF L S C+DV+ECE Y
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQTG--SSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGY 2596
Query: 232 GQEGRPRLCMH-------------ACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQ 278
Q + C+ +C NT GSY+C CP G++ C+D++EC Q
Sbjct: 2597 LQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQ 2656
Query: 279 PVCPQGTTCINTGGSFQCVSPECPEG 304
C G C NT G + C CP G
Sbjct: 2657 APCSYG--CSNTEGGYLC---GCPPG 2677
Score = 73.2 bits (178), Expect = 4e-13
Identities = 63/226 (27%), Positives = 88/226 (38%), Gaps = 32/226 (14%)
Query: 82 PALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECS 141
P L DGR VD + TC G++ + G T + C
Sbjct: 641 PGLAVGLDGR-----VCVDTHMRSTCYGGYKR---GQCIKPLFGAVTKSECCCASTEYAF 692
Query: 142 SQPCQNGGTC-VEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVE 200
+PCQ C + +Y+ +C G A + + + C +
Sbjct: 693 GEPCQ---PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI------CENLR 743
Query: 201 RAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGY 259
C C +G+ + + C D+NEC L LC + C NTPGS+ CTCP G+
Sbjct: 744 GTYKCICNSGYEVDSTGKN--CVDINECVL-----NSLLCDNGQCRNTPGSFVCTCPKGF 796
Query: 260 RTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
D K+CED+DEC C G C N+ GSF C EC S
Sbjct: 797 IYKPDLKTCEDIDECE--SSPCING-VCKNSPGSFIC---ECSSES 836
Score = 69.7 bits (169), Expect = 5e-12
Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 196 CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTC 255
C + + C C GF + VC+D++EC Q G C+NT GSYRC C
Sbjct: 1782 CINMVGSFRCECPVGFFYNDKL--LVCEDIDEC----QNGPVCQRNAECINTAGSYRCDC 1835
Query: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG--SGNVSYVKT 313
GYR + G+ C D +EC + +C G CI+T GSF C+ C G + + +
Sbjct: 1836 KPGYRFTSTGQ-CNDRNECQEIPNICSHG-QCIDTVGSFYCL---CHTGFKTNDDQTMCL 1890
Query: 314 SPFQCERNPC 323
+CER+ C
Sbjct: 1891 DINECERDAC 1900
Score = 67.4 bits (163), Expect = 2e-11
Identities = 42/133 (31%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Query: 134 CRGISECS-SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSR 192
C + EC + CQ+G C + YRC CP G QH + + +
Sbjct: 2565 CEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYL----QHYQWNQCVDENECLSAHICG 2618
Query: 193 APRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYR 252
C + C C AGF +G CQD+NEC G P C + C NT G Y
Sbjct: 2619 GASCHNTLGSYKCMCPAGFQYEQFSGG--CQDINEC---GSAQAP--CSYGCSNTEGGYL 2671
Query: 253 CTCPGGYRTLADG 265
C CP GY + G
Sbjct: 2672 CGCPPGYFRIGQG 2684
Score = 65.9 bits (159), Expect = 7e-11
Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 37/152 (24%)
Query: 134 CRGISECSS---QPCQNGGTCVEGVNQYRCIC-------PPGRTG---NRCQHQAQTAAP 180
C + EC+S C+NG C+ V ++C C P GRT N C + + AP
Sbjct: 1928 CIDVDECASGNGNLCRNG-QCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 1986
Query: 181 EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
C ++ + C C G+ L + C+D++EC P +C
Sbjct: 1987 G-------------TCQNLDGSYRCICPPGYSLQ----NEKCEDIDECV-----EEPEIC 2024
Query: 241 -MHACVNTPGSYRCTCPGGYRTLADGKSCEDV 271
+ C NT GS++C CP G+ + G+ C+D+
Sbjct: 2025 ALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 2056
Score = 63.2 bits (152), Expect = 5e-10
Identities = 73/277 (26%), Positives = 104/277 (37%), Gaps = 62/277 (22%)
Query: 107 CNPGFRLVGPSSVVCL-PNG-TWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP 164
C+ G P S VC P G + + C I EC S PC NG C + C C
Sbjct: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCING-VCKNSPGSFICECSS 834
Query: 165 GRT------------GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCE---- 208
T C E ++ G + S+ C+ + A C
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC--CSSLGAAWGSPCTLCQV 892
Query: 209 ---AGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLAD 264
G S G C+D++ECE++ P +C + CVNT GS++C CP G A
Sbjct: 893 DPICGKGYSRIKGTQ-CEDIDECEVF-----PGVCKNGLCVNTRGSFKCQCPSGMTLDAT 946
Query: 265 GKSCEDV-----------DECVGLQPVCPQ---GTTCINTG---GSFQCV------SPE- 300
G+ C D+ +EC P+ + C + G G+ +C +PE
Sbjct: 947 GRICLDIRLETCFLRYEDEECT--LPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEY 1004
Query: 301 ---CPEGSGNVSYVKTS--PFQCERNPCPMDSRPCRH 332
CP G G + T+ PF + N C M C H
Sbjct: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTH 1041
Score = 60.8 bits (146), Expect = 2e-09
Identities = 55/212 (25%), Positives = 78/212 (36%), Gaps = 21/212 (9%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT--GNR 170
++G C G G C I+EC+ P CV Y C CP G +R
Sbjct: 2184 VIGGFECTC-EEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
Query: 171 CQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECEL 230
+ + EG + C + C C G+ C D NEC+
Sbjct: 2243 RMCKDEDECEEGK---HDCTEKQMECKNLIGTYMCICGPGYQRR--PDGEGCVDENECQT 2297
Query: 231 YGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDE--CVG--LQPVCPQGT 285
+P +C + C+NT GSY C C G+ + C D E C LQ +C G+
Sbjct: 2298 -----KPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS 2352
Query: 286 TCINTGGSFQCVSPECPEGSGNVSYVKTSPFQ 317
+ N +C C G G + + PFQ
Sbjct: 2353 SNRNPVTKSECC---CDGGRGWGPHCEICPFQ 2381
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/114 (32%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 159 RCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAG 218
R P RTG CQ + A G G + C + C C AG L+ +
Sbjct: 233 RGFIPNIRTG-ACQDVDECQAIPGLCQGGN-------CINTVGSFECKCPAGHKLNEVS- 283
Query: 219 DSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDV 271
C+D++EC P +C C NT SY C CP G+ T DG C DV
Sbjct: 284 -QKCEDIDECSTI-----PGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 102 bits (255), Expect = 5e-22
Identities = 76/244 (31%), Positives = 97/244 (39%), Gaps = 33/244 (13%)
Query: 70 GRVGPDALPVSCPALNTPADGR---KFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGT 126
G P P C +N +G G D TC PG+R GP CL
Sbjct: 798 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR-PGPRGASCLD--- 853
Query: 127 WTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAG 186
+ ECS + G C + CICPPG A +
Sbjct: 854 ----------VDECSEEDLCQSGICTNTDGSFECICPPGHRAG--PDLASCLDVDECRER 901
Query: 187 DSAFSRAPRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC-MHA 243
A + RC + C C+ G+H A + C DV+EC+ YG P +C
Sbjct: 902 GPALCGSQRCENSPGSYRCVRDCDPGYH---AGPEGTCDDVDECQEYG----PEICGAQR 954
Query: 244 CVNTPGSYRCT--CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC 301
C NTPGSYRCT C GY+ G C+DVDEC + C C N GSFQC+ +
Sbjct: 955 CENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQG 1012
Query: 302 PEGS 305
EG+
Sbjct: 1013 YEGA 1016
Score = 96.7 bits (239), Expect = 4e-20
Identities = 73/240 (30%), Positives = 95/240 (39%), Gaps = 48/240 (20%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPP 164
C PGFR GP + CL + EC PC G C + C+CP
Sbjct: 547 CGPGFR-AGPRAAECLD-------------VDECHRVPPPCDLG-RCENTPGSFLCVCPA 591
Query: 165 GRT----GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS 220
G G CQ + G + G A C + + C C AGF G +
Sbjct: 592 GYQAAPHGASCQDVDECTQSPG-LCGRGA------CKNLPGSFRCVCPAGFR-----GSA 639
Query: 221 VCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
+DV+EC + P C NT GS+ C CP G+R+ G C+DVDEC P
Sbjct: 640 CEEDVDECA----QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 695
Query: 281 CPQGTTCINTGGSFQCVSP----------ECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
C G C NT GSFQCV P EC + +++ +C +P R C
Sbjct: 696 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC 754
Score = 89.4 bits (220), Expect = 6e-18
Identities = 67/213 (31%), Positives = 85/213 (39%), Gaps = 29/213 (13%)
Query: 127 WTG----EQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTA 178
WTG E G+ + + Q C G C+ + Y C C G G RC +
Sbjct: 467 WTGPEIPESGPSSGMCQRNPQVC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 525
Query: 179 -APEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
P G RC + C C GF A + C DV+EC P
Sbjct: 526 RVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE--CLDVDECHRVP----P 571
Query: 238 RLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
+ C NTPGS+ C CP GY+ G SC+DVDEC +C +G C N GSF+CV
Sbjct: 572 PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRCV 630
Query: 298 SPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
P GS V +C + P P C
Sbjct: 631 CPAGFRGSACEEDVD----ECAQEPPPCGPGRC 659
Score = 89.4 bits (220), Expect = 6e-18
Identities = 71/215 (33%), Positives = 90/215 (41%), Gaps = 31/215 (14%)
Query: 102 EVHFTCNPGFRLVG-PSSVVC--LPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVN 156
E H C PG V P S C P+G + C + ECSS PC G C
Sbjct: 732 ENHLAC-PGQECVNSPGSFQCRTCPSGHHL-HRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
Query: 157 QYRCICPPGRTGNRCQHQAQTAAP------EGSVAGDSAFSRAPRCAQVERAQHCSCEAG 210
+RC C PG ++A + P + GD F C + + C+C G
Sbjct: 790 SFRCSCAPG-------YRAPSGRPGPCADVNECLEGDFCFPHG-ECLNTDGSFACTCAPG 841
Query: 211 FHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCE 269
+ G G S C DV+EC LC C NT GS+ C CP G+R D SC
Sbjct: 842 YR-PGPRGAS-CLDVDECS------EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 893
Query: 270 DVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
DVDEC P C N+ GS++CV +C G
Sbjct: 894 DVDECRERGPALCGSQRCENSPGSYRCVR-DCDPG 927
Score = 66.2 bits (160), Expect = 5e-11
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 192 RAPRCAQVERAQHCS-CEAGFHLSGAAGD-SVCQDVNECELYGQEGRPRLCMHA-CVNTP 248
R +C E A++ S C G +GD S+ +DV+EC+L+ R ++C CVNT
Sbjct: 1152 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF----RDQVCKSGVCVNTA 1207
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
Y C C GY C D DEC +P C +G C+NT GS+ C
Sbjct: 1208 PGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC 1254
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 5/66 (7%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V C C G+ L C D+NEC+ E LC++A C+NT GS+RC
Sbjct: 1480 RCVRVPEGFTCRCFDGYRLDMTR--MACVDINECD--EAEAASPLCVNARCLNTDGSFRC 1535
Query: 254 TCPGGY 259
C G+
Sbjct: 1536 ICRPGF 1541
Score = 45.8 bits (107), Expect = 8e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 244 CVNTPGSYRCTCPGGYRTLADGKSCEDVDEC---VGLQPVCPQGTTCINTGGSFQCV 297
CV P + C C GYR +C D++EC P+C C+NT GSF+C+
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCI 1536
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 11/63 (17%)
Query: 207 CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADG 265
C GF + C+DV+EC G+ C H C NT G Y C CP G+ +
Sbjct: 277 CPTGFERVNGS----CEDVDECATGGR------CQHGECANTRGGYTCVCPDGFLLDSSR 326
Query: 266 KSC 268
SC
Sbjct: 327 SSC 329
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGL 277
G + V++C+L + RL V+ P CP G+ + SCEDVDEC
Sbjct: 247 GAGLAWGVHDCQLCSE----RLGNSERVSAPDG---PCPTGFERV--NGSCEDVDEC-AT 296
Query: 278 QPVCPQGTTCINTGGSFQCVSPECPEG----SGNVSYVKTSPFQCERNPC 323
C G C NT G + CV CP+G S S + + PC
Sbjct: 297 GGRCQHG-ECANTRGGYTCV---CPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 37.4 bits (85), Expect = 0.027
Identities = 31/130 (23%), Positives = 46/130 (35%), Gaps = 13/130 (10%)
Query: 135 RGISECS---SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
R + EC Q C++G CV Y C C G Q A +
Sbjct: 1185 RDVDECQLFRDQVCKSG-VCVNTAPGYSCYCS---NGYYYHTQRLECIDNDECADEEPAC 1240
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGA-----AGDSVCQDVNECELYGQEGRPRLCMHACVN 246
RC + HC+CE L G+ + +S D N + + G +C H ++
Sbjct: 1241 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1300
Query: 247 TPGSY-RCTC 255
+Y C C
Sbjct: 1301 RQATYTECCC 1310
Score = 36.2 bits (82), Expect = 0.061
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%)
Query: 145 CQNGGTCVEGVNQYRCICPPGRTGNRCQ-HQAQTAAPEGSVAG 186
C NGG CV+ RC+CPP G CQ H + P +V G
Sbjct: 90 CHNGGVCVK---PDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 129
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/128 (25%), Positives = 44/128 (34%), Gaps = 30/128 (23%)
Query: 138 SECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVA----------GD 187
S C Q C T +Y+ +CP GR AP G ++
Sbjct: 1149 SGCRIQQCPGTETA-----EYQSLCPHGRG---------YLAPSGDLSLRRDVDECQLFR 1194
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNT 247
++ C C C G++ + C D +EC + P CVNT
Sbjct: 1195 DQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE--CIDNDECA----DEEPACEGGRCVNT 1248
Query: 248 PGSYRCTC 255
GSY CTC
Sbjct: 1249 VGSYHCTC 1256
Score = 30.4 bits (67), Expect = 3.3
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 1/32 (3%)
Query: 134 CRGISECSSQ-PCQNGGTCVEGVNQYRCICPP 164
C EC+ + P GG CV V Y C C P
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 29.3 bits (64), Expect = 7.4
Identities = 30/114 (26%), Positives = 41/114 (35%), Gaps = 16/114 (14%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPG------RTGNRCQHQ-AQTAAPEGSVAG 186
C + EC++ G C Y C+CP G R+ QH ++ P V
Sbjct: 288 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR 347
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
D S P + + Q C C G A CQ C +G EG +C
Sbjct: 348 DGGCS-LPILRNITK-QICCCSR----VGKAWGRGCQ---LCPPFGSEGFREIC 392
Score = 28.9 bits (63), Expect = 9.7
Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 4/51 (7%)
Query: 134 CRGISEC----SSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
C I+EC ++ P C+ +RCIC PG H A P
Sbjct: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 102 bits (255), Expect = 5e-22
Identities = 76/244 (31%), Positives = 97/244 (39%), Gaps = 33/244 (13%)
Query: 70 GRVGPDALPVSCPALNTPADGR---KFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGT 126
G P P C +N +G G D TC PG+R GP CL
Sbjct: 828 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR-PGPRGASCLD--- 883
Query: 127 WTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAG 186
+ ECS + G C + CICPPG A +
Sbjct: 884 ----------VDECSEEDLCQSGICTNTDGSFECICPPGHRAG--PDLASCLDVDECRER 931
Query: 187 DSAFSRAPRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC-MHA 243
A + RC + C C+ G+H A + C DV+EC+ YG P +C
Sbjct: 932 GPALCGSQRCENSPGSYRCVRDCDPGYH---AGPEGTCDDVDECQEYG----PEICGAQR 984
Query: 244 CVNTPGSYRCT--CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC 301
C NTPGSYRCT C GY+ G C+DVDEC + C C N GSFQC+ +
Sbjct: 985 CENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQG 1042
Query: 302 PEGS 305
EG+
Sbjct: 1043 YEGA 1046
Score = 96.7 bits (239), Expect = 4e-20
Identities = 73/240 (30%), Positives = 95/240 (39%), Gaps = 48/240 (20%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPP 164
C PGFR GP + CL + EC PC G C + C+CP
Sbjct: 577 CGPGFR-AGPRAAECLD-------------VDECHRVPPPCDLG-RCENTPGSFLCVCPA 621
Query: 165 GRT----GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS 220
G G CQ + G + G A C + + C C AGF G +
Sbjct: 622 GYQAAPHGASCQDVDECTQSPG-LCGRGA------CKNLPGSFRCVCPAGFR-----GSA 669
Query: 221 VCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
+DV+EC + P C NT GS+ C CP G+R+ G C+DVDEC P
Sbjct: 670 CEEDVDECA----QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 725
Query: 281 CPQGTTCINTGGSFQCVSP----------ECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
C G C NT GSFQCV P EC + +++ +C +P R C
Sbjct: 726 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC 784
Score = 89.4 bits (220), Expect = 6e-18
Identities = 67/213 (31%), Positives = 85/213 (39%), Gaps = 29/213 (13%)
Query: 127 WTG----EQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTA 178
WTG E G+ + + Q C G C+ + Y C C G G RC +
Sbjct: 497 WTGPEIPESGPSSGMCQRNPQVC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 555
Query: 179 -APEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
P G RC + C C GF A + C DV+EC P
Sbjct: 556 RVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE--CLDVDECHRVP----P 601
Query: 238 RLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
+ C NTPGS+ C CP GY+ G SC+DVDEC +C +G C N GSF+CV
Sbjct: 602 PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRCV 660
Query: 298 SPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
P GS V +C + P P C
Sbjct: 661 CPAGFRGSACEEDVD----ECAQEPPPCGPGRC 689
Score = 89.4 bits (220), Expect = 6e-18
Identities = 71/215 (33%), Positives = 90/215 (41%), Gaps = 31/215 (14%)
Query: 102 EVHFTCNPGFRLVG-PSSVVC--LPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVN 156
E H C PG V P S C P+G + C + ECSS PC G C
Sbjct: 762 ENHLAC-PGQECVNSPGSFQCRTCPSGHHL-HRGRCTDVDECSSGAPPCGPHGHCTNTEG 819
Query: 157 QYRCICPPGRTGNRCQHQAQTAAP------EGSVAGDSAFSRAPRCAQVERAQHCSCEAG 210
+RC C PG ++A + P + GD F C + + C+C G
Sbjct: 820 SFRCSCAPG-------YRAPSGRPGPCADVNECLEGDFCFPHG-ECLNTDGSFACTCAPG 871
Query: 211 FHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCE 269
+ G G S C DV+EC LC C NT GS+ C CP G+R D SC
Sbjct: 872 YR-PGPRGAS-CLDVDECS------EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 923
Query: 270 DVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
DVDEC P C N+ GS++CV +C G
Sbjct: 924 DVDECRERGPALCGSQRCENSPGSYRCVR-DCDPG 957
Score = 66.2 bits (160), Expect = 5e-11
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 192 RAPRCAQVERAQHCS-CEAGFHLSGAAGD-SVCQDVNECELYGQEGRPRLCMHA-CVNTP 248
R +C E A++ S C G +GD S+ +DV+EC+L+ R ++C CVNT
Sbjct: 1182 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF----RDQVCKSGVCVNTA 1237
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
Y C C GY C D DEC +P C +G C+NT GS+ C
Sbjct: 1238 PGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC 1284
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 5/66 (7%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V C C G+ L C D+NEC+ E LC++A C+NT GS+RC
Sbjct: 1510 RCVRVPEGFTCRCFDGYRLDMTR--MACVDINECD--EAEAASPLCVNARCLNTDGSFRC 1565
Query: 254 TCPGGY 259
C G+
Sbjct: 1566 ICRPGF 1571
Score = 45.8 bits (107), Expect = 8e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 244 CVNTPGSYRCTCPGGYRTLADGKSCEDVDEC---VGLQPVCPQGTTCINTGGSFQCV 297
CV P + C C GYR +C D++EC P+C C+NT GSF+C+
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCI 1566
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 11/63 (17%)
Query: 207 CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADG 265
C GF + C+DV+EC G+ C H C NT G Y C CP G+ +
Sbjct: 307 CPTGFERVNGS----CEDVDECATGGR------CQHGECANTRGGYTCVCPDGFLLDSSR 356
Query: 266 KSC 268
SC
Sbjct: 357 SSC 359
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGL 277
G + V++C+L + RL V+ P CP G+ + SCEDVDEC
Sbjct: 277 GAGLAWGVHDCQLCSE----RLGNSERVSAPDG---PCPTGFERV--NGSCEDVDEC-AT 326
Query: 278 QPVCPQGTTCINTGGSFQCVSPECPEG----SGNVSYVKTSPFQCERNPC 323
C G C NT G + CV CP+G S S + + PC
Sbjct: 327 GGRCQHG-ECANTRGGYTCV---CPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 37.4 bits (85), Expect = 0.027
Identities = 31/130 (23%), Positives = 46/130 (35%), Gaps = 13/130 (10%)
Query: 135 RGISECS---SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
R + EC Q C++G CV Y C C G Q A +
Sbjct: 1215 RDVDECQLFRDQVCKSG-VCVNTAPGYSCYCS---NGYYYHTQRLECIDNDECADEEPAC 1270
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGA-----AGDSVCQDVNECELYGQEGRPRLCMHACVN 246
RC + HC+CE L G+ + +S D N + + G +C H ++
Sbjct: 1271 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1330
Query: 247 TPGSY-RCTC 255
+Y C C
Sbjct: 1331 RQATYTECCC 1340
Score = 36.2 bits (82), Expect = 0.061
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%)
Query: 145 CQNGGTCVEGVNQYRCICPPGRTGNRCQ-HQAQTAAPEGSVAG 186
C NGG CV+ RC+CPP G CQ H + P +V G
Sbjct: 120 CHNGGVCVK---PDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 159
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/128 (25%), Positives = 44/128 (34%), Gaps = 30/128 (23%)
Query: 138 SECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVA----------GD 187
S C Q C T +Y+ +CP GR AP G ++
Sbjct: 1179 SGCRIQQCPGTETA-----EYQSLCPHGRG---------YLAPSGDLSLRRDVDECQLFR 1224
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNT 247
++ C C C G++ + C D +EC + P CVNT
Sbjct: 1225 DQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE--CIDNDECA----DEEPACEGGRCVNT 1278
Query: 248 PGSYRCTC 255
GSY CTC
Sbjct: 1279 VGSYHCTC 1286
Score = 30.4 bits (67), Expect = 3.3
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 1/32 (3%)
Query: 134 CRGISECSSQ-PCQNGGTCVEGVNQYRCICPP 164
C EC+ + P GG CV V Y C C P
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 29.3 bits (64), Expect = 7.4
Identities = 30/114 (26%), Positives = 41/114 (35%), Gaps = 16/114 (14%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPG------RTGNRCQHQ-AQTAAPEGSVAG 186
C + EC++ G C Y C+CP G R+ QH ++ P V
Sbjct: 318 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR 377
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
D S P + + Q C C G A CQ C +G EG +C
Sbjct: 378 DGGCS-LPILRNITK-QICCCSR----VGKAWGRGCQ---LCPPFGSEGFREIC 422
Score = 28.9 bits (63), Expect = 9.7
Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 4/51 (7%)
Query: 134 CRGISEC----SSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
C I+EC ++ P C+ +RCIC PG H A P
Sbjct: 1535 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1585
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 102 bits (255), Expect = 5e-22
Identities = 76/244 (31%), Positives = 97/244 (39%), Gaps = 33/244 (13%)
Query: 70 GRVGPDALPVSCPALNTPADGR---KFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGT 126
G P P C +N +G G D TC PG+R GP CL
Sbjct: 865 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR-PGPRGASCLD--- 920
Query: 127 WTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAG 186
+ ECS + G C + CICPPG A +
Sbjct: 921 ----------VDECSEEDLCQSGICTNTDGSFECICPPGHRAG--PDLASCLDVDECRER 968
Query: 187 DSAFSRAPRCAQVERAQHC--SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC-MHA 243
A + RC + C C+ G+H A + C DV+EC+ YG P +C
Sbjct: 969 GPALCGSQRCENSPGSYRCVRDCDPGYH---AGPEGTCDDVDECQEYG----PEICGAQR 1021
Query: 244 CVNTPGSYRCT--CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPEC 301
C NTPGSYRCT C GY+ G C+DVDEC + C C N GSFQC+ +
Sbjct: 1022 CENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQG 1079
Query: 302 PEGS 305
EG+
Sbjct: 1080 YEGA 1083
Score = 96.7 bits (239), Expect = 4e-20
Identities = 73/240 (30%), Positives = 95/240 (39%), Gaps = 48/240 (20%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVNQYRCICPP 164
C PGFR GP + CL + EC PC G C + C+CP
Sbjct: 614 CGPGFR-AGPRAAECLD-------------VDECHRVPPPCDLG-RCENTPGSFLCVCPA 658
Query: 165 GRT----GNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS 220
G G CQ + G + G A C + + C C AGF G +
Sbjct: 659 GYQAAPHGASCQDVDECTQSPG-LCGRGA------CKNLPGSFRCVCPAGFR-----GSA 706
Query: 221 VCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
+DV+EC + P C NT GS+ C CP G+R+ G C+DVDEC P
Sbjct: 707 CEEDVDECA----QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 762
Query: 281 CPQGTTCINTGGSFQCVSP----------ECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
C G C NT GSFQCV P EC + +++ +C +P R C
Sbjct: 763 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC 821
Score = 89.4 bits (220), Expect = 6e-18
Identities = 67/213 (31%), Positives = 85/213 (39%), Gaps = 29/213 (13%)
Query: 127 WTG----EQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG----RTGNRCQHQAQTA 178
WTG E G+ + + Q C G C+ + Y C C G G RC +
Sbjct: 534 WTGPEIPESGPSSGMCQRNPQVC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 592
Query: 179 -APEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
P G RC + C C GF A + C DV+EC P
Sbjct: 593 RVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE--CLDVDECHRVP----P 638
Query: 238 RLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
+ C NTPGS+ C CP GY+ G SC+DVDEC +C +G C N GSF+CV
Sbjct: 639 PCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRCV 697
Query: 298 SPECPEGSGNVSYVKTSPFQCERNPCPMDSRPC 330
P GS V +C + P P C
Sbjct: 698 CPAGFRGSACEEDVD----ECAQEPPPCGPGRC 726
Score = 89.4 bits (220), Expect = 6e-18
Identities = 71/215 (33%), Positives = 90/215 (41%), Gaps = 31/215 (14%)
Query: 102 EVHFTCNPGFRLVG-PSSVVC--LPNGTWTGEQPHCRGISECSS--QPCQNGGTCVEGVN 156
E H C PG V P S C P+G + C + ECSS PC G C
Sbjct: 799 ENHLAC-PGQECVNSPGSFQCRTCPSGHHL-HRGRCTDVDECSSGAPPCGPHGHCTNTEG 856
Query: 157 QYRCICPPGRTGNRCQHQAQTAAP------EGSVAGDSAFSRAPRCAQVERAQHCSCEAG 210
+RC C PG ++A + P + GD F C + + C+C G
Sbjct: 857 SFRCSCAPG-------YRAPSGRPGPCADVNECLEGDFCFPHG-ECLNTDGSFACTCAPG 908
Query: 211 FHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCE 269
+ G G S C DV+EC LC C NT GS+ C CP G+R D SC
Sbjct: 909 YR-PGPRGAS-CLDVDECS------EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 960
Query: 270 DVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
DVDEC P C N+ GS++CV +C G
Sbjct: 961 DVDECRERGPALCGSQRCENSPGSYRCVR-DCDPG 994
Score = 66.2 bits (160), Expect = 5e-11
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 192 RAPRCAQVERAQHCS-CEAGFHLSGAAGD-SVCQDVNECELYGQEGRPRLCMHA-CVNTP 248
R +C E A++ S C G +GD S+ +DV+EC+L+ R ++C CVNT
Sbjct: 1219 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF----RDQVCKSGVCVNTA 1274
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
Y C C GY C D DEC +P C +G C+NT GS+ C
Sbjct: 1275 PGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC 1321
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 5/66 (7%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V C C G+ L C D+NEC+ E LC++A C+NT GS+RC
Sbjct: 1547 RCVRVPEGFTCRCFDGYRLDMTR--MACVDINECD--EAEAASPLCVNARCLNTDGSFRC 1602
Query: 254 TCPGGY 259
C G+
Sbjct: 1603 ICRPGF 1608
Score = 45.8 bits (107), Expect = 8e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 244 CVNTPGSYRCTCPGGYRTLADGKSCEDVDEC---VGLQPVCPQGTTCINTGGSFQCV 297
CV P + C C GYR +C D++EC P+C C+NT GSF+C+
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCI 1603
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 11/63 (17%)
Query: 207 CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADG 265
C GF + C+DV+EC G+ C H C NT G Y C CP G+ +
Sbjct: 344 CPTGFERVNGS----CEDVDECATGGR------CQHGECANTRGGYTCVCPDGFLLDSSR 393
Query: 266 KSC 268
SC
Sbjct: 394 SSC 396
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 218 GDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGL 277
G + V++C+L + RL V+ P CP G+ + SCEDVDEC
Sbjct: 314 GAGLAWGVHDCQLCSE----RLGNSERVSAPDG---PCPTGFERV--NGSCEDVDEC-AT 363
Query: 278 QPVCPQGTTCINTGGSFQCVSPECPEG----SGNVSYVKTSPFQCERNPC 323
C G C NT G + CV CP+G S S + + PC
Sbjct: 364 GGRCQHG-ECANTRGGYTCV---CPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 37.4 bits (85), Expect = 0.027
Identities = 31/130 (23%), Positives = 46/130 (35%), Gaps = 13/130 (10%)
Query: 135 RGISECS---SQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
R + EC Q C++G CV Y C C G Q A +
Sbjct: 1252 RDVDECQLFRDQVCKSG-VCVNTAPGYSCYCS---NGYYYHTQRLECIDNDECADEEPAC 1307
Query: 192 RAPRCAQVERAQHCSCEAGFHLSGA-----AGDSVCQDVNECELYGQEGRPRLCMHACVN 246
RC + HC+CE L G+ + +S D N + + G +C H ++
Sbjct: 1308 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1367
Query: 247 TPGSY-RCTC 255
+Y C C
Sbjct: 1368 RQATYTECCC 1377
Score = 36.2 bits (82), Expect = 0.061
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%)
Query: 145 CQNGGTCVEGVNQYRCICPPGRTGNRCQ-HQAQTAAPEGSVAG 186
C NGG CV+ RC+CPP G CQ H + P +V G
Sbjct: 157 CHNGGVCVK---PDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 196
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/128 (25%), Positives = 44/128 (34%), Gaps = 30/128 (23%)
Query: 138 SECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVA----------GD 187
S C Q C T +Y+ +CP GR AP G ++
Sbjct: 1216 SGCRIQQCPGTETA-----EYQSLCPHGRG---------YLAPSGDLSLRRDVDECQLFR 1261
Query: 188 SAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNT 247
++ C C C G++ + C D +EC + P CVNT
Sbjct: 1262 DQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE--CIDNDECA----DEEPACEGGRCVNT 1315
Query: 248 PGSYRCTC 255
GSY CTC
Sbjct: 1316 VGSYHCTC 1323
Score = 30.4 bits (67), Expect = 3.3
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 1/32 (3%)
Query: 134 CRGISECSSQ-PCQNGGTCVEGVNQYRCICPP 164
C EC+ + P GG CV V Y C C P
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 29.3 bits (64), Expect = 7.4
Identities = 30/114 (26%), Positives = 41/114 (35%), Gaps = 16/114 (14%)
Query: 134 CRGISECSSQPCQNGGTCVEGVNQYRCICPPG------RTGNRCQHQ-AQTAAPEGSVAG 186
C + EC++ G C Y C+CP G R+ QH ++ P V
Sbjct: 355 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR 414
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
D S P + + Q C C G A CQ C +G EG +C
Sbjct: 415 DGGCS-LPILRNITK-QICCCSR----VGKAWGRGCQ---LCPPFGSEGFREIC 459
Score = 28.9 bits (63), Expect = 9.7
Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 4/51 (7%)
Query: 134 CRGISEC----SSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
C I+EC ++ P C+ +RCIC PG H A P
Sbjct: 1572 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1622
>gi|192447438 protein S, alpha preproprotein [Homo sapiens]
Length = 676
Score = 100 bits (248), Expect = 3e-21
Identities = 55/161 (34%), Positives = 77/161 (47%), Gaps = 18/161 (11%)
Query: 139 ECSSQPCQNGG--TCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRC 196
+CS PC G +C +G + C C PG G +C+ ++ G + C
Sbjct: 120 QCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCS----QIC 175
Query: 197 AQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTC 255
+ HCSC+ GF + D C+DV+EC L +P +C A C N PG + C C
Sbjct: 176 DNTPGSYHCSCKNGFVMLSNKKD--CKDVDECSL-----KPSICGTAVCKNIPGDFECEC 228
Query: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
P GYR KSCED+DEC + +C Q C+N G + C
Sbjct: 229 PEGYRYNLKSKSCEDIDEC--SENMCAQ--LCVNYPGGYTC 265
Score = 72.0 bits (175), Expect = 1e-12
Identities = 40/109 (36%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 196 CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTC 255
C + + C+C+ G+ G+ D+NEC+ C C NTPGSY C+C
Sbjct: 134 CKDGKASFTCTCKPGWQ-----GEKCEFDINECK--DPSNINGGCSQICDNTPGSYHCSC 186
Query: 256 PGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEG 304
G+ L++ K C+DVDEC L+P C N G F+C ECPEG
Sbjct: 187 KNGFVMLSNKKDCKDVDEC-SLKPSICGTAVCKNIPGDFEC---ECPEG 231
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 98.6 bits (244), Expect = 1e-20
Identities = 68/225 (30%), Positives = 86/225 (38%), Gaps = 50/225 (22%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG------- 165
L G C T T + HCR I EC G C +RC C G
Sbjct: 1057 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAK 1116
Query: 166 ---RTGNRCQHQ-----AQTAAPEGSVA-----------------------GDSAFSRAP 194
+ CQH+ Q EGS D + +
Sbjct: 1117 DQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRG 1176
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC--MHACVNTPGSYR 252
C + C+C GF L + CQD+NECE P LC C+NT GS+
Sbjct: 1177 DCINTAGSYDCTCPDGFQLDD---NKTCQDINECE------HPGLCGPQGECLNTEGSFH 1227
Query: 253 CTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C C G+ ADG++CED+DECV VC C NT GSF+C+
Sbjct: 1228 CVCQQGFSISADGRTCEDIDECVN-NTVCDSHGFCDNTAGSFRCL 1271
Score = 92.4 bits (228), Expect = 7e-19
Identities = 64/196 (32%), Positives = 83/196 (42%), Gaps = 36/196 (18%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISEC--SSQPCQNGGTCVEGVNQYRCICPPG------- 165
G VC +G HC I+EC CQ G C+ Y C CP G
Sbjct: 1141 GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNK 1199
Query: 166 --RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQ 223
+ N C+H P+G C E + HC C+ GF +S A C+
Sbjct: 1200 TCQDINECEHPG-LCGPQGE------------CLNTEGSFHCVCQQGFSIS--ADGRTCE 1244
Query: 224 DVNECELYGQEGRPRLC-MHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
D++EC +C H C NT GS+RC C G++ DG+ C DV+EC L VC
Sbjct: 1245 DIDECV------NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC 1298
Query: 282 PQGTTCINTGGSFQCV 297
+ C N GSF CV
Sbjct: 1299 GE-AFCENVEGSFLCV 1313
Score = 89.7 bits (221), Expect = 5e-18
Identities = 63/204 (30%), Positives = 91/204 (44%), Gaps = 28/204 (13%)
Query: 130 EQPHCRGISECSSQPCQNGGTCVEGVNQYRCI-CPPGRTG--NRCQHQAQTAAPEGSVAG 186
++ C I EC + CV Y+C+ C G G +C + P G
Sbjct: 993 QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG 1052
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CV 245
D C+ +E + CSC G+ + C+D++EC Q+G LC++ C
Sbjct: 1053 D--------CSNLEGSYMCSCHKGY--TRTPDHKHCRDIDEC----QQGN--LCVNGQCK 1096
Query: 246 NTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
NT GS+RCTC GY+ A CED+DEC + +C G C NT GSFQCV + S
Sbjct: 1097 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHG-QCRNTEGSFQCVCDQGYRAS 1154
Query: 306 G------NVSYVKTSPFQCERNPC 323
G +++ C+R C
Sbjct: 1155 GLGDHCEDINECLEDKSVCQRGDC 1178
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/182 (30%), Positives = 73/182 (40%), Gaps = 25/182 (13%)
Query: 161 ICPPGRTGNRCQHQAQTAAPE-GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGD 219
+ P T + Q A T E + A C + C C G+ S
Sbjct: 854 VAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ--Q 911
Query: 220 SVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQ 278
C D++EC LC C NT GS+ C CP G+ +G +C DVDEC L+
Sbjct: 912 RKCVDIDECTQV-----QHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC--LR 964
Query: 279 P-VCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCE-----RNPCPMDSRPCRH 332
P VC +G C+NT G+F+C C G Y T +CE NP C +
Sbjct: 965 PDVCGEG-HCVNTVGAFRC--EYCDSG-----YRMTQRGRCEDIDECLNPSTCPDEQCVN 1016
Query: 333 LP 334
P
Sbjct: 1017 SP 1018
Score = 57.0 bits (136), Expect = 3e-08
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V+ C C G+HL A C DVNEC+ R LC +A C+NT GSY+C
Sbjct: 1636 RCVRVQEGYTCDCFDGYHLDTAK--MTCVDVNECDELNN--RMSLCKNAKCINTDGSYKC 1691
Query: 254 TCPGGYRTLADGKSCEDVDECVGLQ 278
C GY C ++ + L+
Sbjct: 1692 LCLPGYVPSDKPNYCTPLNTALNLE 1716
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/108 (33%), Positives = 46/108 (42%), Gaps = 11/108 (10%)
Query: 194 PRCAQVERAQHCSCEAGF----HLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTP 248
P E + C GF S AG +D +EC L+GQE +C + C+NT
Sbjct: 1391 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQE----ICKNGFCLNTR 1446
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
Y C C G C D+DEC C G C+NT GS+ C
Sbjct: 1447 PGYECYCKQGTYYDPVKLQCFDMDECQDPSS-CIDGQ-CVNTEGSYNC 1492
Score = 46.2 bits (108), Expect = 6e-05
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 14/92 (15%)
Query: 182 GSVAGDSAFSRAPRCAQVERA----QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
G+V F++ +C + Q C G+ ++ CQD+NEC+L G
Sbjct: 583 GTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK---RVNNTFCQDINECQLQG----- 634
Query: 238 RLCMHA-CVNTPGSYRCTCPGGYRTLADGKSC 268
+C + C+NT GSYRCTC G+ SC
Sbjct: 635 -VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 15/79 (18%)
Query: 222 CQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQ--- 278
C +N CE GR CV Y C C GY +C DV+EC L
Sbjct: 1626 CGILNGCE----NGR-------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRM 1674
Query: 279 PVCPQGTTCINTGGSFQCV 297
+C + CINT GS++C+
Sbjct: 1675 SLC-KNAKCINTDGSYKCL 1692
Score = 39.3 bits (90), Expect = 0.007
Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGN----VSY 310
C GY+ + + C+D++EC LQ VCP G C+NT GS++C C G G S
Sbjct: 612 CLPGYKRV-NNTFCQDINECQ-LQGVCPNGE-CLNTMGSYRCT---CKIGFGPDPTFSSC 665
Query: 311 VKTSP-FQCERNPC---PMDSRPCRH 332
V P E+ PC R C H
Sbjct: 666 VPDPPVISEEKGPCYRLVSSGRQCMH 691
Score = 36.2 bits (82), Expect = 0.061
Identities = 36/156 (23%), Positives = 52/156 (33%), Gaps = 27/156 (17%)
Query: 140 CSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPR---- 195
C PC V G ++ +CP G+ + A E D
Sbjct: 1385 CEIFPCP-----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1439
Query: 196 --CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYR 252
C C C+ G + C D++EC+ P C+ CVNT GSY
Sbjct: 1440 GFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQ------DPSSCIDGQCVNTEGSYN 1491
Query: 253 CTC-------PGGYRTLADGKSCEDVDECVGLQPVC 281
C C R + +S E ++E Q +C
Sbjct: 1492 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC 1527
Score = 35.0 bits (79), Expect = 0.14
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 144 PCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQ 203
PCQNGG C+ C+C PG G C+ A G S + + + A+
Sbjct: 194 PCQNGGMCLR---PQLCVCKPGTKGKACETIAAQDTSSPVFGGQSPGAASSWGPPEQAAK 250
Query: 204 HCS 206
H S
Sbjct: 251 HTS 253
Score = 33.9 bits (76), Expect = 0.30
Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 144 PCQNGGTCVEGVNQYRCICPPGRTGNRCQ 172
PC NGG C ++ +C CPP TG CQ
Sbjct: 406 PCMNGGQCS---SRDKCQCPPNFTGKLCQ 431
Score = 32.3 bits (72), Expect = 0.88
Identities = 32/138 (23%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
CLP G C+ I+EC Q G C+ + YRC C + G + P
Sbjct: 612 CLP-GYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTC---KIGFGPDPTFSSCVP 667
Query: 181 EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
+ V + + P V + C HL+ +C C G+ P C
Sbjct: 668 DPPVISE---EKGPCYRLVSSGRQCMHPLSVHLT----KQLC-----CCSVGKAWGPH-C 714
Query: 241 MHACVNTPGSYRCTCPGG 258
+ +++ CPGG
Sbjct: 715 EKCPLPGTAAFKEICPGG 732
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 98.6 bits (244), Expect = 1e-20
Identities = 68/225 (30%), Positives = 86/225 (38%), Gaps = 50/225 (22%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPG------- 165
L G C T T + HCR I EC G C +RC C G
Sbjct: 731 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAK 790
Query: 166 ---RTGNRCQHQ-----AQTAAPEGSVA-----------------------GDSAFSRAP 194
+ CQH+ Q EGS D + +
Sbjct: 791 DQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRG 850
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC--MHACVNTPGSYR 252
C + C+C GF L + CQD+NECE P LC C+NT GS+
Sbjct: 851 DCINTAGSYDCTCPDGFQLDD---NKTCQDINECE------HPGLCGPQGECLNTEGSFH 901
Query: 253 CTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCV 297
C C G+ ADG++CED+DECV VC C NT GSF+C+
Sbjct: 902 CVCQQGFSISADGRTCEDIDECVN-NTVCDSHGFCDNTAGSFRCL 945
Score = 92.4 bits (228), Expect = 7e-19
Identities = 64/196 (32%), Positives = 83/196 (42%), Gaps = 36/196 (18%)
Query: 115 GPSSVVCLPNGTWTGEQPHCRGISEC--SSQPCQNGGTCVEGVNQYRCICPPG------- 165
G VC +G HC I+EC CQ G C+ Y C CP G
Sbjct: 815 GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNK 873
Query: 166 --RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQ 223
+ N C+H P+G C E + HC C+ GF +S A C+
Sbjct: 874 TCQDINECEHPG-LCGPQGE------------CLNTEGSFHCVCQQGFSIS--ADGRTCE 918
Query: 224 DVNECELYGQEGRPRLC-MHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVC 281
D++EC +C H C NT GS+RC C G++ DG+ C DV+EC L VC
Sbjct: 919 DIDECV------NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC 972
Query: 282 PQGTTCINTGGSFQCV 297
+ C N GSF CV
Sbjct: 973 GE-AFCENVEGSFLCV 987
Score = 89.7 bits (221), Expect = 5e-18
Identities = 63/204 (30%), Positives = 91/204 (44%), Gaps = 28/204 (13%)
Query: 130 EQPHCRGISECSSQPCQNGGTCVEGVNQYRCI-CPPGRTG--NRCQHQAQTAAPEGSVAG 186
++ C I EC + CV Y+C+ C G G +C + P G
Sbjct: 667 QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG 726
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CV 245
D C+ +E + CSC G+ + C+D++EC Q+G LC++ C
Sbjct: 727 D--------CSNLEGSYMCSCHKGY--TRTPDHKHCRDIDEC----QQGN--LCVNGQCK 770
Query: 246 NTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 305
NT GS+RCTC GY+ A CED+DEC + +C G C NT GSFQCV + S
Sbjct: 771 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHG-QCRNTEGSFQCVCDQGYRAS 828
Query: 306 G------NVSYVKTSPFQCERNPC 323
G +++ C+R C
Sbjct: 829 GLGDHCEDINECLEDKSVCQRGDC 852
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/182 (30%), Positives = 73/182 (40%), Gaps = 25/182 (13%)
Query: 161 ICPPGRTGNRCQHQAQTAAPE-GSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGD 219
+ P T + Q A T E + A C + C C G+ S
Sbjct: 528 VAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ--Q 585
Query: 220 SVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQ 278
C D++EC LC C NT GS+ C CP G+ +G +C DVDEC L+
Sbjct: 586 RKCVDIDECTQV-----QHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC--LR 638
Query: 279 P-VCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCE-----RNPCPMDSRPCRH 332
P VC +G C+NT G+F+C C G Y T +CE NP C +
Sbjct: 639 PDVCGEG-HCVNTVGAFRC--EYCDSG-----YRMTQRGRCEDIDECLNPSTCPDEQCVN 690
Query: 333 LP 334
P
Sbjct: 691 SP 692
Score = 57.0 bits (136), Expect = 3e-08
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYRC 253
RC +V+ C C G+HL A C DVNEC+ R LC +A C+NT GSY+C
Sbjct: 1310 RCVRVQEGYTCDCFDGYHLDTAK--MTCVDVNECDELNN--RMSLCKNAKCINTDGSYKC 1365
Query: 254 TCPGGYRTLADGKSCEDVDECVGLQ 278
C GY C ++ + L+
Sbjct: 1366 LCLPGYVPSDKPNYCTPLNTALNLE 1390
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/108 (33%), Positives = 46/108 (42%), Gaps = 11/108 (10%)
Query: 194 PRCAQVERAQHCSCEAGF----HLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTP 248
P E + C GF S AG +D +EC L+GQE +C + C+NT
Sbjct: 1065 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQE----ICKNGFCLNTR 1120
Query: 249 GSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
Y C C G C D+DEC C G C+NT GS+ C
Sbjct: 1121 PGYECYCKQGTYYDPVKLQCFDMDECQDPSS-CIDGQ-CVNTEGSYNC 1166
Score = 46.2 bits (108), Expect = 6e-05
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 14/92 (15%)
Query: 182 GSVAGDSAFSRAPRCAQVERA----QHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRP 237
G+V F++ +C + Q C G+ ++ CQD+NEC+L G
Sbjct: 257 GTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK---RVNNTFCQDINECQLQG----- 308
Query: 238 RLCMHA-CVNTPGSYRCTCPGGYRTLADGKSC 268
+C + C+NT GSYRCTC G+ SC
Sbjct: 309 -VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 15/79 (18%)
Query: 222 CQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQ--- 278
C +N CE GR CV Y C C GY +C DV+EC L
Sbjct: 1300 CGILNGCE----NGR-------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRM 1348
Query: 279 PVCPQGTTCINTGGSFQCV 297
+C + CINT GS++C+
Sbjct: 1349 SLC-KNAKCINTDGSYKCL 1366
Score = 39.3 bits (90), Expect = 0.007
Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 255 CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGN----VSY 310
C GY+ + + C+D++EC LQ VCP G C+NT GS++C C G G S
Sbjct: 286 CLPGYKRV-NNTFCQDINECQ-LQGVCPNGE-CLNTMGSYRCT---CKIGFGPDPTFSSC 339
Query: 311 VKTSP-FQCERNPC---PMDSRPCRH 332
V P E+ PC R C H
Sbjct: 340 VPDPPVISEEKGPCYRLVSSGRQCMH 365
Score = 36.2 bits (82), Expect = 0.061
Identities = 36/156 (23%), Positives = 52/156 (33%), Gaps = 27/156 (17%)
Query: 140 CSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPR---- 195
C PC V G ++ +CP G+ + A E D
Sbjct: 1059 CEIFPCP-----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1113
Query: 196 --CAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHA-CVNTPGSYR 252
C C C+ G + C D++EC+ P C+ CVNT GSY
Sbjct: 1114 GFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQ------DPSSCIDGQCVNTEGSYN 1165
Query: 253 CTC-------PGGYRTLADGKSCEDVDECVGLQPVC 281
C C R + +S E ++E Q +C
Sbjct: 1166 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC 1201
Score = 33.9 bits (76), Expect = 0.30
Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 144 PCQNGGTCVEGVNQYRCICPPGRTGNRCQ 172
PC NGG C ++ +C CPP TG CQ
Sbjct: 80 PCMNGGQCS---SRDKCQCPPNFTGKLCQ 105
Score = 32.3 bits (72), Expect = 0.88
Identities = 32/138 (23%), Positives = 49/138 (35%), Gaps = 17/138 (12%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
CLP G C+ I+EC Q G C+ + YRC C + G + P
Sbjct: 286 CLP-GYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTC---KIGFGPDPTFSSCVP 341
Query: 181 EGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
+ V + + P V + C HL+ +C C G+ P C
Sbjct: 342 DPPVISE---EKGPCYRLVSSGRQCMHPLSVHLT----KQLC-----CCSVGKAWGPH-C 388
Query: 241 MHACVNTPGSYRCTCPGG 258
+ +++ CPGG
Sbjct: 389 EKCPLPGTAAFKEICPGG 406
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 97.1 bits (240), Expect = 3e-20
Identities = 72/208 (34%), Positives = 93/208 (44%), Gaps = 40/208 (19%)
Query: 121 CLPNGTWTGEQPHCR-GISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAA 179
C P WTG P C I +CS C +GGTC + VN ++C+CPP TG CQ A
Sbjct: 362 CSPG--WTG--PTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECE 417
Query: 180 PEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRL 239
+ V A C + + +C C L G G + ++N+C GQ
Sbjct: 418 AKPCV-------NAKSCKNLIASYYCDC-----LPGWMGQNCDININDC--LGQ------ 457
Query: 240 CMH--ACVNTPGSYRCTCPGGYRTLADGKSCE-DVDECVGLQPVCPQGTTCINTGGSFQC 296
C + +C + YRC CP GY G CE D+DEC C G C N FQC
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECA--SNPCLNGGHCQNEINRFQC 511
Query: 297 VSPECPEG-SGNVSYVKTSPFQCERNPC 323
+ CP G SGN+ + CE NPC
Sbjct: 512 L---CPTGFSGNLCQLDID--YCEPNPC 534
Score = 91.7 bits (226), Expect = 1e-18
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 38/239 (15%)
Query: 113 LVGPSSVVCLPNGTWTGEQPHC-RGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRC 171
LV +C P + G+ HC R I EC+S PC NGG C +N+++C+CP G +GN C
Sbjct: 467 LVNGYRCICPPG--YAGD--HCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLC 522
Query: 172 QHQAQTAAPEGSVAGDSAFSRAP----RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNE 227
Q P G ++RA +C + ++CS HL + C+ ++
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS-----HLKDHCRTTPCEVIDS 577
Query: 228 CELY-----GQEGRPRLCMHAC-------VNTPGSYRCTCPGGYRTLADGKSC-EDVDEC 274
C + EG + + C + G + C C G+ G C E++++C
Sbjct: 578 CTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTYCHENINDC 633
Query: 275 VGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHL 333
C G TCI+ S++C+ + EG +Y +T+ C +NPC + CR L
Sbjct: 634 E--SNPCRNGGTCIDGVNSYKCICSDGWEG----AYCETNINDCSQNPC-HNGGTCRDL 685
Score = 79.0 bits (193), Expect = 8e-15
Identities = 63/242 (26%), Positives = 81/242 (33%), Gaps = 48/242 (19%)
Query: 106 TCNPGFRLVGPSSVV-CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP 164
TCN G C+ G W G + S C PC NGGTCV + C+C
Sbjct: 713 TCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKE 772
Query: 165 GRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQD 224
G G C +P + C + C C GF AG +
Sbjct: 773 GWEGPICAQNTNDCSPHPCY-------NSGTCVDGDNWYRCECAPGF-----AGPDCRIN 820
Query: 225 VNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVD--ECVGLQPVCP 282
+NEC + P CV+ YRC CP G+ G C++V C+ + V P
Sbjct: 821 INEC-----QSSPCAFGATCVDEINGYRCVCPPGH----SGAKCQEVSGRPCITMGSVIP 871
Query: 283 QG-------TTCINTGGSFQCVS--------------PECPEGSGNVSYVKTSPFQCERN 321
G TC G C ECP G S + QC +
Sbjct: 872 DGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQ---SCIPILDDQCFVH 928
Query: 322 PC 323
PC
Sbjct: 929 PC 930
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/236 (25%), Positives = 92/236 (38%), Gaps = 52/236 (22%)
Query: 108 NPGFRLVGPSSVVCLPNGTWTGEQPHCR-GISECSSQPCQNGGTCVEGVNQYRCICPPGR 166
N G + G +S C+ + W G +C I++CS PC NGGTC + VN + C C G
Sbjct: 640 NGGTCIDGVNSYKCICSDGWEGA--YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW 697
Query: 167 TGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFH-------------- 212
G C + S ++ + C A C C G+
Sbjct: 698 KGKTCHSR-------DSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLP 750
Query: 213 ----------LSGAAGDSVCQDVNE---CELYGQEGRPRLCMHA--CVNTPGSYRCTCPG 257
++G + VC++ E C + P C ++ CV+ YRC C
Sbjct: 751 NPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAP 810
Query: 258 GYRTLADGKSCE-DVDECVGLQPVCPQGTTCINTGGSFQCVSP------ECPEGSG 306
G+ G C +++EC C G TC++ ++CV P +C E SG
Sbjct: 811 GFA----GPDCRININEC--QSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSG 860
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 97.1 bits (240), Expect = 3e-20
Identities = 81/262 (30%), Positives = 109/262 (41%), Gaps = 58/262 (22%)
Query: 80 SCPALNTPADGRKFGSK-YLVDHEVHFTCN--PGFRLVGPSSVVC-----------LPNG 125
SC LN A G + ++ H+ CN PG+RL VC P+G
Sbjct: 657 SCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 126 TWTGE---------QPH--------CRGISECSS-QPCQNGGTCVEGVNQYRCICP---- 163
+ QP CR ++EC+ PC + G C +RC C
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTCAQGYA 775
Query: 164 PGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQ 223
P G C + A G V + S P Q C C +G+HLS S C+
Sbjct: 776 PAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQ------CQCLSGYHLS--RDRSHCE 825
Query: 224 DVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCP 282
D++EC+ P C+ C+NT GSYRC CP G+R L G+ C+D+DEC +C
Sbjct: 826 DIDECDF------PAACIGGDCINTNGSYRCLCPQGHR-LVGGRKCQDIDECSQDPSLCL 878
Query: 283 QGTTCINTGGSFQCVSPECPEG 304
C N GS+ CV C EG
Sbjct: 879 PHGACKNLQGSYVCV---CDEG 897
Score = 95.5 bits (236), Expect = 8e-20
Identities = 75/238 (31%), Positives = 93/238 (39%), Gaps = 61/238 (25%)
Query: 107 CNPGFRLVGPSSVVCLPNGTWTGEQPH--CRGISECSSQPCQNG-GTCVEGVNQYRCICP 163
C G + GP C N + H C ++EC ++PC G G C+ Y C C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN 644
Query: 164 PGRT------GNRCQHQAQTAAPEGSVAGDSAF--------------------SRAPRCA 197
G G C + A P + GD F SR P C
Sbjct: 645 RGYRLHVGAGGRSCVDLNECAKPH--LCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 702
Query: 198 QVERAQHCS------------------CEAGFHLSGAAGDSVCQDVNECELYGQEGRPRL 239
++ + S C+ G+ + G C+DVNEC EG P
Sbjct: 703 DIDECRDPSSCPDGKCENKPGSFKCIACQPGYR---SQGGGACRDVNECA----EGSP-- 753
Query: 240 CMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQC 296
C C N PGS+RCTC GY DG+SC DVDEC VC G C NT GSFQC
Sbjct: 754 CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GDVCDNG-ICSNTPGSFQC 809
Score = 67.8 bits (164), Expect = 2e-11
Identities = 46/175 (26%), Positives = 66/175 (37%), Gaps = 24/175 (13%)
Query: 107 CNPGF--RLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPP 164
C+PG+ L G C + C + EC + + G C ++C C
Sbjct: 754 CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLS 813
Query: 165 G----RTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDS 220
G R + C+ + P + GD C + C C G L G
Sbjct: 814 GYHLSRDRSHCEDIDECDFPAACIGGD--------CINTNGSYRCLCPQGHRL---VGGR 862
Query: 221 VCQDVNECELYGQEGRPRLCMH--ACVNTPGSYRCTCPGGYRTLADGKSCEDVDE 273
CQD++EC P LC+ AC N GSY C C G+ D CE+V++
Sbjct: 863 KCQDIDECSQ-----DPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 912
Score = 65.1 bits (157), Expect = 1e-10
Identities = 88/349 (25%), Positives = 118/349 (33%), Gaps = 98/349 (28%)
Query: 74 PDALPVSCPALNTPA-DGRKFGSKYLVDH-EVHFTCNPGFRLVGPSSVVC--LPNGTWTG 129
P + +C PA DGR S VD E C+ G P S C L +
Sbjct: 763 PGSFRCTCAQGYAPAPDGR---SCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSR 819
Query: 130 EQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRT---GNRCQ------HQAQTAAP 180
++ HC I EC GG C+ YRC+CP G G +CQ P
Sbjct: 820 DRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLP 879
Query: 181 EGSVAG---------DSAFSRAPR---CAQVERAQH------------------------ 204
G+ D F+ C +VE+ H
Sbjct: 880 HGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQ 939
Query: 205 ----CSCEAGFH----------LSGAAGDSVC--------------------QDVNECEL 230
CS AG+ S A S+C +D++EC L
Sbjct: 940 QECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECML 999
Query: 231 YGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
+G E +C CVNT Y C C G+ + C DVDEC+ + C G C N
Sbjct: 1000 FGSE----ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD-ESNCRNG-VCEN 1053
Query: 290 TGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPC--PMDSRP--CRHLP 334
T G ++C P SP + + + C P RP C +LP
Sbjct: 1054 TRGGYRCACTP-PAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLP 1101
Score = 64.3 bits (155), Expect = 2e-10
Identities = 59/222 (26%), Positives = 76/222 (34%), Gaps = 45/222 (20%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNG-----GTCVEGVNQYRCICPP----GRTGNRC 171
C P ++ Q C E CQ+ G CV YRC C P G +G C
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1121
Query: 172 QHQAQTA--APEG-----SVAGDSAFSRAPRCAQVERAQHCSCE---------------- 208
Q A APE S G+ P C C
Sbjct: 1122 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRG 1181
Query: 209 AGFHLSGAAGDSVCQDVNECELYGQEGRP-----------RLCMHACVNTPGSYRCTCPG 257
AG H + +S L G+ R R CV PG C CPG
Sbjct: 1182 AGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPG 1241
Query: 258 GYRTLADGKSCEDVDEC--VGLQPVCPQGTTCINTGGSFQCV 297
G++ A C D+DEC + + + + C+NT GSF+CV
Sbjct: 1242 GFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1283
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/197 (25%), Positives = 73/197 (37%), Gaps = 32/197 (16%)
Query: 140 CSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP-----EGSVAGDSAFSRAP 194
C PC V ++ +CP G+ + + P + + S +
Sbjct: 954 CEIYPCP-----VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG 1008
Query: 195 RCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNEC--ELYGQEGRPRLCMHACVNTPGSYR 252
+C + C C+ GF+ G + C DV+EC E + G C NT G YR
Sbjct: 1009 KCVNTQPGYECYCKQGFYYDGNLLE--CVDVDECLDESNCRNG-------VCENTRGGYR 1059
Query: 253 CTCPGGYRTLADGKSC-----EDVDECVGLQPVCPQGTTCINTGGSF--QCVSPECPEGS 305
C C + C DVDEC P + C+N GS+ +C P P S
Sbjct: 1060 CACTPPAEYSPAQRQCLSPEEMDVDECQ--DPAACRPGRCVNLPGSYRCECRPPWVPGPS 1117
Query: 306 GNVSYVKTSPFQCERNP 322
G + SP ER P
Sbjct: 1118 GRDCQLPESP--AERAP 1132
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 21/80 (26%)
Query: 222 CQDVNECELYGQEGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPV 280
CQD+NEC + P +C H C+N PGSYRC CP G+ +L ++ +C+ +P
Sbjct: 353 CQDINECAM------PGVCRHGDCLNNPGSYRCVCPPGH-SLGPSRT-----QCIADKP- 399
Query: 281 CPQGTTCINTGGSFQCVSPE 300
+ + C F+ VSPE
Sbjct: 400 -EEKSLC------FRLVSPE 412
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/116 (31%), Positives = 44/116 (37%), Gaps = 22/116 (18%)
Query: 162 CPPGRTGNRCQHQAQTA---------------APEGSVAGDSAFSR--APRCAQVERAQH 204
CPP G+ C + E S DS R + RC
Sbjct: 1177 CPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAV 1236
Query: 205 CSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCM-HACVNTPGSYRCTCPGGY 259
C C GF L A + C D++EC Q G LC CVNT GS+RC C G+
Sbjct: 1237 CECPGGFQLD--ASRARCVDIDECRELNQRGL--LCKSERCVNTSGSFRCVCKAGF 1288
Score = 43.5 bits (101), Expect = 4e-04
Identities = 41/147 (27%), Positives = 53/147 (36%), Gaps = 22/147 (14%)
Query: 132 PHCRGISEC---SSQPCQNGGTCVEGVNQYRCICPPG--RTGNRCQHQAQTAAPEGSVAG 186
P R I EC S+ C+ G CV Y C C G GN + +
Sbjct: 989 PAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFYYDGNLLE------CVDVDECL 1041
Query: 187 DSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVC---QDVNECELYGQEGRPRLCMHA 243
D + R C C+C S A + DV+EC+ P C
Sbjct: 1042 DESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ------DPAACRPG 1095
Query: 244 -CVNTPGSYRCTCPGGYRTLADGKSCE 269
CVN PGSYRC C + G+ C+
Sbjct: 1096 RCVNLPGSYRCECRPPWVPGPSGRDCQ 1122
Score = 42.7 bits (99), Expect = 6e-04
Identities = 19/59 (32%), Positives = 26/59 (44%)
Query: 123 PNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPE 181
P G HC+ I+EC+ G C+ YRC+CPPG + + Q PE
Sbjct: 342 PQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPE 400
Score = 35.8 bits (81), Expect = 0.079
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 9/48 (18%)
Query: 144 PCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFS 191
PC NGG C ++ +C+CPP TG CQ P G G + S
Sbjct: 116 PCMNGGQCS---SRNQCLCPPDFTGRFCQ------VPAGGAGGGTGGS 154
Score = 34.7 bits (78), Expect = 0.18
Identities = 21/88 (23%), Positives = 29/88 (32%), Gaps = 1/88 (1%)
Query: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAP 180
C + G C + EC + G C YRC C P + Q Q +
Sbjct: 1021 CKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEE 1080
Query: 181 -EGSVAGDSAFSRAPRCAQVERAQHCSC 207
+ D A R RC + + C C
Sbjct: 1081 MDVDECQDPAACRPGRCVNLPGSYRCEC 1108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,943,886
Number of Sequences: 37866
Number of extensions: 1152258
Number of successful extensions: 6780
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 247
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 2811
Number of HSP's gapped (non-prelim): 2033
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.