Guide to the Human Genome
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Search of human proteins with 189095271

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189095271 phospholipase A2, group VII [Homo sapiens]
         (441 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189095271 phospholipase A2, group VII [Homo sapiens]               912   0.0  
gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo sa...   306   2e-83
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...    33   0.40 
gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]                   32   1.5  
gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]                    31   2.0  
gi|20270371 carboxymethylenebutenolidase [Homo sapiens]                30   4.4  
gi|7705415 hook homolog 1 [Homo sapiens]                               30   5.7  
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog...    30   5.7  
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         30   5.7  
gi|94721347 heparanase [Homo sapiens]                                  29   7.5  
gi|148746204 heparanase [Homo sapiens]                                 29   7.5  
gi|19924141 like-glycosyltransferase [Homo sapiens]                    29   9.7  
gi|4758664 like-glycosyltransferase [Homo sapiens]                     29   9.7  
gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]            29   9.7  
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    29   9.7  
gi|74316009 MAWD binding protein isoform b [Homo sapiens]              29   9.7  
gi|62177133 MAWD binding protein isoform a [Homo sapiens]              29   9.7  

>gi|189095271 phospholipase A2, group VII [Homo sapiens]
          Length = 441

 Score =  912 bits (2358), Expect = 0.0
 Identities = 441/441 (100%), Positives = 441/441 (100%)

Query: 1   MVPPKLHVLFCLCGCLAVVYPFDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGN 60
           MVPPKLHVLFCLCGCLAVVYPFDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGN
Sbjct: 1   MVPPKLHVLFCLCGCLAVVYPFDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGN 60

Query: 61  GPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNI 120
           GPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNI
Sbjct: 61  GPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNI 120

Query: 121 LRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR 180
           LRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR
Sbjct: 121 LRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR 180

Query: 181 DRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDID 240
           DRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDID
Sbjct: 181 DRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDID 240

Query: 241 HGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMF 300
           HGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMF
Sbjct: 241 HGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMF 300

Query: 301 PLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFA 360
           PLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFA
Sbjct: 301 PLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFA 360

Query: 361 TGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGT 420
           TGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGT
Sbjct: 361 TGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGT 420

Query: 421 NINTTNQHIMLQNSSGIEKYN 441
           NINTTNQHIMLQNSSGIEKYN
Sbjct: 421 NINTTNQHIMLQNSSGIEKYN 441


>gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo
           sapiens]
          Length = 392

 Score =  306 bits (784), Expect = 2e-83
 Identities = 163/375 (43%), Positives = 234/375 (62%), Gaps = 12/375 (3%)

Query: 57  PRGNGPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRL--DTLWIPNKEYFWGLSKFLGTH 114
           P   GP+ VGC D+M     +G+F RL+YP Q  +      LWIP  EY  GL+++L  +
Sbjct: 10  PPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCTGLAEYLQFN 69

Query: 115 WLMGNIL-RLLFGSMTTPANWNSPLRPGEK-YPLVVFSHGLGAFRTLYSAIGIDLASHGF 172
              G +L  L  GS   P +WN P +  +  YPL++FSHGLGAFRTLYSA  ++LAS GF
Sbjct: 70  KRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMELASRGF 129

Query: 173 IVAAVEHRDRSASATYYFK-----DQSAAEIGDKSWLYLRTLKQ-EEETHIRNEQVRQRA 226
           +VA  EHRDRSA+ TY+ K     +Q   E   + W+  R +++ E+E H+RN QV QR 
Sbjct: 130 VVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHVRNPQVHQRV 189

Query: 227 KECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSED 286
            EC + L ++ ++  G+ V N L    D+  LK +ID  ++AV+GHSFGGAT I  L+++
Sbjct: 190 SECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGATAILALAKE 249

Query: 287 QRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITI 346
            +FRC +ALDAWMFPL  + Y +   P+FFIN+E FQ   ++  MKK  +  ++ ++IT+
Sbjct: 250 TQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQHEQSRIITV 309

Query: 347 RGSVHQNFADFTFATGKIIGHML--KLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQ 404
            GSVH++  DF F TG +IG     + +G +D     ++  +A LAFLQKHL L +D++Q
Sbjct: 310 LGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKHLDLKEDYNQ 369

Query: 405 WDCLIEGDDENLIPG 419
           W+ LIEG   +L PG
Sbjct: 370 WNNLIEGIGPSLTPG 384


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 306 VYSRIPQP-LFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSV 350
           VY R PQ  LFF+  EY+ Y     KM+K Y  + E +   + G +
Sbjct: 398 VYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQI 443


>gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]
          Length = 558

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 22/110 (20%)

Query: 190 FKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDI---------- 239
           F D+ A+ + DK    LRT + EE+   R   + +  K C+  LSL   I          
Sbjct: 73  FFDRGASIVEDKLVKDLRTQESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVI 132

Query: 240 --------DHGKPVKNAL----DLKFDMEQLKDSIDREKIAVIGHSFGGA 277
                    H  P K  +    D+  D  +   S+   K AV+   FGGA
Sbjct: 133 EGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182


>gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]
          Length = 558

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 22/110 (20%)

Query: 190 FKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDI---------- 239
           F D+ A+ + DK    LRT + EE+   R   + +  K C+  LSL   I          
Sbjct: 73  FFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVI 132

Query: 240 --------DHGKPVKNAL----DLKFDMEQLKDSIDREKIAVIGHSFGGA 277
                    H  P K  +    D+  D  +   S+   K AV+   FGGA
Sbjct: 133 EGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182


>gi|20270371 carboxymethylenebutenolidase [Homo sapiens]
          Length = 245

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 16/66 (24%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 255 MEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPL 314
           ++ LK     +KI ++G  +GG  V   + +   FR G+++   +    +++Y+ +  P 
Sbjct: 114 LKYLKQQCHAQKIGIVGFCWGGTAVHHLMMKYSEFRAGVSVYG-IVKDSEDIYN-LKNPT 171

Query: 315 FFINSE 320
            FI +E
Sbjct: 172 LFIFAE 177


>gi|7705415 hook homolog 1 [Homo sapiens]
          Length = 728

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 198 IGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQ 257
           +G+      R L++ +E     E++RQR +E    ++ + D  +    +N + +   ++Q
Sbjct: 173 VGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEM-MNEKLDQ 231

Query: 258 LKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALD 296
           L  S D     V    F     ++ L E + FR   A D
Sbjct: 232 LDGSFDDPNTVVAKKYFHAQLQLEQLQE-ENFRLEAAKD 269


>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
           [Homo sapiens]
          Length = 766

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 19/79 (24%), Positives = 38/79 (48%)

Query: 210 KQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAV 269
           +Q E T        +  KE  Q ++L   +    P   +L +   +E+L+D  +R++  +
Sbjct: 534 QQSERTPNNRPDAPKEKKEKEQLINLQNFLTTQSPSVRSLAVPTIIEELEDEEERDQRQM 593

Query: 270 IGHSFGGATVIQTLSEDQR 288
           I  +F G  VI+   +++R
Sbjct: 594 IKEAFAGDDVIRDFLKEKR 612


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 17/73 (23%), Positives = 40/73 (54%), Gaps = 6/73 (8%)

Query: 206 LRTLKQEEETHIRNEQVRQRAKEC-----SQALSLILDIDHGKPVKNALDLKFDMEQLK- 259
           L+  +QEEET +R ++  QR KE      ++   +  ++D  +  K+    K ++E+ + 
Sbjct: 692 LQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRL 751

Query: 260 DSIDREKIAVIGH 272
           +  ++E++ ++ H
Sbjct: 752 EEQEKEQVMLVAH 764


>gi|94721347 heparanase [Homo sapiens]
          Length = 543

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 17/88 (19%)

Query: 76  NKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRL------LFGSMT 129
           N   +LRL YP             NK+    L + LG H L+   ++L      +    T
Sbjct: 459 NVTKYLRLPYP-----------FSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQT 507

Query: 130 TPANWNSPLRPGEKYPLVVFSHGLGAFR 157
            P     PLRPG    L  FS+     R
Sbjct: 508 LPPLMEKPLRPGSSLGLPAFSYSFFVIR 535


>gi|148746204 heparanase [Homo sapiens]
          Length = 543

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 17/88 (19%)

Query: 76  NKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRL------LFGSMT 129
           N   +LRL YP             NK+    L + LG H L+   ++L      +    T
Sbjct: 459 NVTKYLRLPYP-----------FSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQT 507

Query: 130 TPANWNSPLRPGEKYPLVVFSHGLGAFR 157
            P     PLRPG    L  FS+     R
Sbjct: 508 LPPLMEKPLRPGSSLGLPAFSYSFFVIR 535


>gi|19924141 like-glycosyltransferase [Homo sapiens]
          Length = 756

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 81  LRLYYPSQDNDRLDTLWIPNKEY--FWGLSKFLGTHWLMGNILRLL 124
           +R+ + + D  + +  WIPNK Y   +GL K + T  L  N+ R++
Sbjct: 194 VRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVI 239


>gi|4758664 like-glycosyltransferase [Homo sapiens]
          Length = 756

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 81  LRLYYPSQDNDRLDTLWIPNKEY--FWGLSKFLGTHWLMGNILRLL 124
           +R+ + + D  + +  WIPNK Y   +GL K + T  L  N+ R++
Sbjct: 194 VRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVI 239


>gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]
          Length = 847

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 124 LFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAI-GI------DLASHGFIVAA 176
           L+G +  P +    L+PG+KYP V+F +G    + + +   G+       LAS G++V  
Sbjct: 646 LYGMLYKPHD----LQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVV 701

Query: 177 VE-----HRDRSASATYYFKDQSAAEIGDKSWLYLRT 208
           ++     HR       + +K  + A      W++  T
Sbjct: 702 IDNRGSCHRGLKFEGAFKYKMVAIAGAPVTLWIFYDT 738


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
            sapiens]
          Length = 2715

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 106  GLSKFLGTHWLMGNILRLLFGSMTTPANWNSPLRPG--EKYPLVVFSHGLGAFRTLYSAI 163
            GL +F  TH     IL    G      + +S   PG    +P+   +  +GA  +L  A+
Sbjct: 2193 GLEQFSATHGHTPIILNGWHGESAMDLSCSSEGSPGATSPFPVSASTPKIGAISSLQGAL 2252

Query: 164  GIDLASHGFIVAAVEH 179
            G+DL+  G + A + H
Sbjct: 2253 GMDLS--GILQAGLIH 2266


>gi|74316009 MAWD binding protein isoform b [Homo sapiens]
          Length = 280

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 20/106 (18%)

Query: 282 TLSEDQRFRC---GIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPD 338
           TLS + R R    GI LD  ++P         PQ    +         N +    CYSPD
Sbjct: 105 TLSGELRARRAEDGIVLDLPLYPAH-------PQDFHEVEDLIKTAIGNTLVQDICYSPD 157

Query: 339 KERKMITIRGSVHQNFADFTFA----------TGKIIGHMLKLKGD 374
            ++ ++ +    +++F +              TGK+ G +L LKG+
Sbjct: 158 TQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGE 203


>gi|62177133 MAWD binding protein isoform a [Homo sapiens]
          Length = 288

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 20/106 (18%)

Query: 282 TLSEDQRFRC---GIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPD 338
           TLS + R R    GI LD  ++P         PQ    +         N +    CYSPD
Sbjct: 105 TLSGELRARRAEDGIVLDLPLYPAH-------PQDFHEVEDLIKTAIGNTLVQDICYSPD 157

Query: 339 KERKMITIRGSVHQNFADFTFA----------TGKIIGHMLKLKGD 374
            ++ ++ +    +++F +              TGK+ G +L LKG+
Sbjct: 158 TQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGE 203


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,980,402
Number of Sequences: 37866
Number of extensions: 721826
Number of successful extensions: 1642
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1632
Number of HSP's gapped (non-prelim): 17
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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