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Search of human proteins with 187761343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
(576 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 1177 0.0
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 1177 0.0
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 133 4e-31
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 130 3e-30
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 129 1e-29
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 123 4e-28
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 122 7e-28
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 122 7e-28
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 114 2e-25
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 110 3e-24
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 109 6e-24
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 109 6e-24
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 103 6e-22
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 103 6e-22
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 98 2e-20
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 90 6e-18
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 89 1e-17
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 89 1e-17
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 89 1e-17
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 88 2e-17
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 87 5e-17
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 85 2e-16
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 82 2e-15
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 75 2e-13
gi|27477105 lipidosin [Homo sapiens] 72 2e-12
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 71 2e-12
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 70 5e-12
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 70 7e-12
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 68 3e-11
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 67 3e-11
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 1177 bits (3046), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV
Sbjct: 1 MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
Query: 61 DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG
Sbjct: 61 DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
Query: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE
Sbjct: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
Query: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH
Sbjct: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
Query: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL
Sbjct: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
Query: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI
Sbjct: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
Query: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE
Sbjct: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
Query: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV
Sbjct: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 1177 bits (3046), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV
Sbjct: 1 MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
Query: 61 DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG
Sbjct: 61 DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
Query: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE
Sbjct: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
Query: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH
Sbjct: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
Query: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL
Sbjct: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
Query: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI
Sbjct: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
Query: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE
Sbjct: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
Query: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV
Sbjct: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 133 bits (335), Expect = 4e-31
Identities = 136/525 (25%), Positives = 233/525 (44%), Gaps = 64/525 (12%)
Query: 67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
++REL S S + + + + CG GD R++ + + + A +G + +P
Sbjct: 90 SFRELGSLSRKAANVLTKPCGLQRGD----RLAVILPRIPEWWLVNVACIRTGIIFMPGT 145
Query: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAIYTG--AVEE 181
+ A + Y + S++ ++AS+E + +V + L LL ++P + G + +E
Sbjct: 146 IQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLL-VSPQSWNGWLSFQE 204
Query: 182 PAEVPVPEQGWRNKGAM----IIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKD-D 236
+ E G+ I +TSGTTG PK + ++ T W K D
Sbjct: 205 LFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSD 264
Query: 237 VILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR-INVFMAVPT 295
+I ++ V + ++ W+ CV + + Q + FL + T I + PT
Sbjct: 265 IIWNMSDTGWVKAAIGSVFSS-WLCGACVFVHRMA-QFDTDTFLDTLTTYPITTLCSPPT 322
Query: 296 IYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERY 355
+Y L+ Q L+ + +R ++G L VLE+W+ TG L E Y
Sbjct: 323 VYRMLV------------QKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGY 370
Query: 356 GMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVT 415
G TE+GM + ++ PGS+G + V+I+ EN G +
Sbjct: 371 GQTEVGMICANQKGQEIK-PGSMGKGMLPYDVQIIDEN-----------------GNVLP 412
Query: 416 PGFEEKEGELLVRGPSV-----FREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIR 469
PG KEGE+ +R F +Y + P++T + D ++ TGD V+ DG +W
Sbjct: 413 PG---KEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD-FYVTGDRGVMDSDGYFWFV 468
Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
GR D+I + GY++ EVE L+ HP++ + AV+ PD G+ V A V L
Sbjct: 469 GRAD-DVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSY 527
Query: 530 H-----RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
+ EL++ + APY P ++ V+E+P+ GKI + L
Sbjct: 528 NPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 130 bits (327), Expect = 3e-30
Identities = 134/531 (25%), Positives = 225/531 (42%), Gaps = 72/531 (13%)
Query: 65 RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
R ++ EL S S + + + C GD RV + + +A A +G V +P
Sbjct: 94 RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
+ + Y + S+++ ++ + ++L+P V + L +
Sbjct: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
Query: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
++ ++ + N+ I +TSGT+G PK TH + ++ W
Sbjct: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
Query: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
T DV+ + +++ P W+ CV +P F P + + S+ P I
Sbjct: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
Query: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
VF + PT+Y L+ Q+ + + + ++ VS + V EKW+N TG
Sbjct: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
Query: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGD 408
+ E YG TE + + G PGS+G P P V+IV N
Sbjct: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN--------------- 413
Query: 409 ERGTKVTPGFEEKEG-ELLVRGP-SVFREYWNKPEETKSAFTLDG-WFKTGDT-VVFKDG 464
G + PG E G ++L P +F Y + P +T S TL G ++ TGD + KDG
Sbjct: 414 --GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAS--TLRGNFYITGDRGYMDKDG 469
Query: 465 QYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLRE 524
+W R D+I + GY++ EVE L HPS+ + AV+ PD G+ V A V L
Sbjct: 470 YFWFVARAD-DVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNP 528
Query: 525 GHSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
+ SH +E++E + APY P ++ ++E+P+ GK + L
Sbjct: 529 DYK-SHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 129 bits (323), Expect = 1e-29
Identities = 137/530 (25%), Positives = 220/530 (41%), Gaps = 75/530 (14%)
Query: 67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
++ EL +S + + + CG GD R+ + + + A +G V +P
Sbjct: 91 SFEELGKQSRKAANVLGGACGLQPGD----RMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146
Query: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPA--- 183
+ L+Y + S++ ++ S L+P V + L + P
Sbjct: 147 TQLTEKDLKYRLQASRAKSIITSDS----LAPRVDAISAECPSLQTKLLVSDSSRPGWLN 202
Query: 184 ------EVPVPEQGWRNKGA---MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWT 233
E R K I +TSGTTG PK V + + +W A T
Sbjct: 203 FRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALT 262
Query: 234 KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR--INVFM 291
+ D+ + V L W +C+ + E +V K + + + I
Sbjct: 263 ESDIFWNTTDTGWVKAAWT--LFSAWPNGSCIFVHELP--RVDAKVILNTLSKFPITTLC 318
Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
VPTI+ L+ Q+ L + +R ++G AL V EKWK+ TG L
Sbjct: 319 CVPTIFRLLV------------QEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVEL 366
Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
E YG +E + + P ++ GS+G P V+IV D+ G
Sbjct: 367 YEGYGQSETVVICANPKGMKIK-SGSMGKASPPYDVQIV-----------------DDEG 408
Query: 412 TKVTPGFEEKEGELLVR-GPS----VFREYWNKPEETKSAFTLDGWFKTGDTV-VFKDGQ 465
+ PG +EG + VR P+ F Y + PE+T ++ D ++ TGD + KDG
Sbjct: 409 NVLPPG---EEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGD-FYITGDRARMDKDGY 464
Query: 466 YWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREG 525
+W GR D+I + Y++ +EVE L HP++ + AV+ PD G+ V A + L
Sbjct: 465 FWFMGRND-DVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPA 523
Query: 526 HSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
+S SH REL+E + V APY P ++ V E+P+ GKI + L
Sbjct: 524 YS-SHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 123 bits (309), Expect = 4e-28
Identities = 129/525 (24%), Positives = 225/525 (42%), Gaps = 67/525 (12%)
Query: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
+REL S + + + CG GD RV+ + + + +G + +P
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGD----RVAVVLPRVPEWWLVILGCIRAGLIFMPGTI 138
Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
+ + + Y + S++ ++A E ++ + V + L + LL + + +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
E + + + + I +TSGT+G PK ++ ++ GL K WT
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV--MMPEFSPQQVWEKFLSSETPRINVFMA 292
D++ + + ++ +L+ P +GA ++P+F P + K LSS I M
Sbjct: 254 SDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMMG 310
Query: 293 VPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL 352
P +Y L++ + PH Q+ + G + LP LE W+ TG +
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTV-----------GESLLP-ETLENWRAQTGLDIR 358
Query: 353 ERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
E YG TE G+ T ++ PG +GT V+I+ D++G
Sbjct: 359 ESYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQII-----------------DDKGN 400
Query: 413 KVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRG 470
+ PG E G + +R +F Y + P++T + D W + +DG + G
Sbjct: 401 VLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMG 460
Query: 471 RTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH 530
R DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LSH
Sbjct: 461 RAD-DIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVL-ASQFLSH 518
Query: 531 ------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
+EL++ ++V APY P ++ V +P+ GKI + L
Sbjct: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 122 bits (307), Expect = 7e-28
Identities = 129/526 (24%), Positives = 222/526 (42%), Gaps = 69/526 (13%)
Query: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
+REL S + + + CG GD RV+ + + + +G + +P
Sbjct: 83 FRELSENSQQAANILSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138
Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
+ + + Y + S++ ++A E ++ + V + L + LL + + +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
E + + + + I +TSGT+G PK ++ ++ GL K WT
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
D++ + + ++ +LL W C ++P+F P + K LSS I M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309
Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
P +Y L++ + PH Q+ L G + LP LE W+ TG +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357
Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
E YG TE G+ T ++ PG +GT V+++ D++G
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVI-----------------DDKG 399
Query: 412 TKVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
+ PG E G + +R +F Y P++T + D W + +DG +
Sbjct: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 459
Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS
Sbjct: 460 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 517
Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
H +EL++ ++V APY P ++ V +P+ GKI + L
Sbjct: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 122 bits (307), Expect = 7e-28
Identities = 129/526 (24%), Positives = 222/526 (42%), Gaps = 69/526 (13%)
Query: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
+REL S + + + CG GD RV+ + + + +G + +P
Sbjct: 83 FRELSENSQQAANILSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138
Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
+ + + Y + S++ ++A E ++ + V + L + LL + + +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
E + + + + I +TSGT+G PK ++ ++ GL K WT
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
D++ + + ++ +LL W C ++P+F P + K LSS I M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309
Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
P +Y L++ + PH Q+ L G + LP LE W+ TG +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357
Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
E YG TE G+ T ++ PG +GT V+++ D++G
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVI-----------------DDKG 399
Query: 412 TKVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
+ PG E G + +R +F Y P++T + D W + +DG +
Sbjct: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 459
Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS
Sbjct: 460 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 517
Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
H +EL++ ++V APY P ++ V +P+ GKI + L
Sbjct: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 114 bits (285), Expect = 2e-25
Identities = 141/565 (24%), Positives = 232/565 (41%), Gaps = 88/565 (15%)
Query: 48 TRALAFGDRIALVDQHG--RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCAND 105
T A +R ALV H R T+ +L + + + + C G +R+ N
Sbjct: 80 TTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKG-----DRLGMWGPNS 134
Query: 106 ASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVL-----ASQEYLELLSPV- 159
++V+ Q A+ +G + V + + A +LEYV+ ++ +Q+Y +L +
Sbjct: 135 YAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC 194
Query: 160 ---------------------VRKLGVPL---LPLTPAIYTGAVEEPAEVPVPEQGWRN- 194
V + PL L L + G+ + + Q + +
Sbjct: 195 PEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSC 254
Query: 195 -KGAMIIYTSGTTGRPKGVLSTHQNI--RAVVTGLVHKWAWTKDDVILHVLP--LHHVHG 249
I +TSGTTG PKG +H NI + + G K + + +LP L+H G
Sbjct: 255 HDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLG 314
Query: 250 VVNALLCPLWVGATCVMM-PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHF 308
V + L GAT ++ P F+ ++ E +S E R PT++ ++
Sbjct: 315 SVAGTMMCLMYGATLILASPIFNGKKALEA-ISRE--RGTFLYGTPTMFVDILN------ 365
Query: 309 TQPHAQDF-LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG- 366
QP + + +C +++GS A P + I L+ YG TE
Sbjct: 366 -QPDFSSYDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420
Query: 367 -PLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKV---TPGFEEKE 422
P T + SVG +P + RI++ E GT TPG
Sbjct: 421 FPEDTVEQKAESVGRIMPHTEARIMNM----------------EAGTLAKLNTPG----- 459
Query: 423 GELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGG 481
EL +RG V YW +P++T+ A D W+ TGD + G I GR S D+I GG
Sbjct: 460 -ELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR-SKDMIIRGG 517
Query: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVL 541
+ E+E HP + +V V+GV D G+ + A + L++G + E+K + + +
Sbjct: 518 ENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKI 577
Query: 542 APYAVPSELVLVEEIPRNQMGKIDK 566
+ + +P +V V P GKI K
Sbjct: 578 SHFKIPKYIVFVTNYPLTISGKIQK 602
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 110 bits (276), Expect = 3e-24
Identities = 106/384 (27%), Positives = 169/384 (44%), Gaps = 48/384 (12%)
Query: 198 MIIYTSGTTGRPKGVLSTHQ-NIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
+I +TSGTTG PK +H ++ G + DV + + + L+
Sbjct: 222 VIFFTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVE 281
Query: 257 PLWVGATCVM--MPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQ 314
P G T + +P+F + + + L IN F V +IY +++ Q
Sbjct: 282 PWTAGCTVFIHHLPQFDTKVIIQTLLKYP---INHFWGVSSIYRMILQ-----------Q 327
Query: 315 DFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
DF G LP E+WK TG L E YG +E G+ + ++
Sbjct: 328 DFTSIRFPALEHCYTGGEVVLPKDQ-EEWKRRTGLLLYENYGQSETGLICATYWGMKIK- 385
Query: 375 PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELL--VRGPSV 432
PG +G P V+++ D++G+ + P E G + VR S+
Sbjct: 386 PGFMGKATPPYDVQVI-----------------DDKGSILPPNTEGNIGIRIKPVRPVSL 428
Query: 433 FREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEW 491
F Y PE+T D ++ TGD + ++G GR+ DII GY++ EVE
Sbjct: 429 FMCYEGDPEKTAKVECGD-FYNTGDRGKMDEEGYICFLGRSD-DIINASGYRIGPAEVES 486
Query: 492 HLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH------RELKEWARNVLAPYA 545
L+ HP++ + AV+G PD G+ V A + L LSH +EL++ ++V APY
Sbjct: 487 ALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTP-QFLSHDKDQLTKELQQHVKSVTAPYK 545
Query: 546 VPSELVLVEEIPRNQMGKIDKKAL 569
P ++ V E+P+ GKI++K L
Sbjct: 546 YPRKVEFVSELPKTITGKIERKEL 569
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 109 bits (273), Expect = 6e-24
Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%)
Query: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
+REL S + + + CG GD RV+ + + + +G + +P
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138
Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
+ + + Y + S++ ++A E ++ + V + L + LL + + +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
E + + + + I +TSGT+G PK ++ ++ GL K WT
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
D++ + + ++ +LL W C ++P+F P + K LSS I M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309
Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
P +Y L++ + PH Q+ L G + LP LE W+ TG +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357
Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
E YG TE G+ T ++ PG +GT V++++ +H
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400
Query: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
+ G+L G F + P++T + D W + +DG +
Sbjct: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453
Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS
Sbjct: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511
Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
H +EL++ ++V APY P ++ V +P+ GKI + L
Sbjct: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 109 bits (273), Expect = 6e-24
Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%)
Query: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
+REL S + + + CG GD RV+ + + + +G + +P
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138
Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
+ + + Y + S++ ++A E ++ + V + L + LL + + +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
E + + + + I +TSGT+G PK ++ ++ GL K WT
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
D++ + + ++ +LL W C ++P+F P + K LSS I M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309
Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
P +Y L++ + PH Q+ L G + LP LE W+ TG +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357
Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
E YG TE G+ T ++ PG +GT V++++ +H
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400
Query: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
+ G+L G F + P++T + D W + +DG +
Sbjct: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453
Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS
Sbjct: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511
Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
H +EL++ ++V APY P ++ V +P+ GKI + L
Sbjct: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 103 bits (256), Expect = 6e-22
Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)
Query: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
I+YTSG+TG+PKGV+ T V T + + + +DV + + G P
Sbjct: 326 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 385
Query: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
L GAT V+ + S + ++ F PT LM++ D T+
Sbjct: 386 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 439
Query: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
+ L V G+ P+ P W + + G +++ + TE G + PL A
Sbjct: 440 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 494
Query: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
+ PGS P GV I++E+ + EG+ G V F++ P
Sbjct: 495 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 536
Query: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
+ R + E ++ + G++ TGD +DG YWI GR D++ G+ +S
Sbjct: 537 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 595
Query: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
EVE L+ H ++ + AV+G P G+ + VTL +GH+ S + ELK+ R + P
Sbjct: 596 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 655
Query: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
A P + +P+ + GKI ++ L
Sbjct: 656 ATPDYIQNAPGLPKTRSGKIMRRVL 680
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 103 bits (256), Expect = 6e-22
Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)
Query: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
I+YTSG+TG+PKGV+ T V T + + + +DV + + G P
Sbjct: 313 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 372
Query: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
L GAT V+ + S + ++ F PT LM++ D T+
Sbjct: 373 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 426
Query: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
+ L V G+ P+ P W + + G +++ + TE G + PL A
Sbjct: 427 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 481
Query: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
+ PGS P GV I++E+ + EG+ G V F++ P
Sbjct: 482 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 523
Query: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
+ R + E ++ + G++ TGD +DG YWI GR D++ G+ +S
Sbjct: 524 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 582
Query: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
EVE L+ H ++ + AV+G P G+ + VTL +GH+ S + ELK+ R + P
Sbjct: 583 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 642
Query: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
A P + +P+ + GKI ++ L
Sbjct: 643 ATPDYIQNAPGLPKTRSGKIMRRVL 667
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 97.8 bits (242), Expect = 2e-20
Identities = 135/551 (24%), Positives = 224/551 (40%), Gaps = 88/551 (15%)
Query: 65 RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
R TYREL + RL+ + R G R +RV+ V A A G V
Sbjct: 140 RITYRELLETTCRLANTLKR-----HGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTV 194
Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPV-VRKLGVPLLPLTPAI--------- 174
++ A L I D++ VV+ + L V ++K+ + P +
Sbjct: 195 IFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRT 254
Query: 175 ----YTGAVEEPAE--------VPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
+ G ++ P E V PE ++YTSG+TG PKG++ T +
Sbjct: 255 DNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGY-LL 313
Query: 223 VTGLVHKWAWTKD--DVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQ-----QV 275
L HK + D+ V + + G + PL GAT V+ E +P +
Sbjct: 314 YAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF-ESTPVYPNAGRY 372
Query: 276 WEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAAL 335
WE + E +IN F PT L++Y D + + + + LR + GS
Sbjct: 373 WE---TVERLKINQFYGAPTAVRLLLKYGDA-WVKKYDRSSLRTL----------GSVGE 418
Query: 336 PLPVLEKWK---NITGH---TLLERYGMTEIGMALSGPLTT---AVRLPGSVGTPLPGVQ 386
P+ E W+ + G TL++ + TE G P + A LP P G+
Sbjct: 419 PINC-EAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIV 477
Query: 387 VRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRG--PSVFREYWNKPEETK 444
++ DE+G+ V G L + P + R + +
Sbjct: 478 PVLM-----------------DEKGSVVEGS--NVSGALCISQAWPGMARTIYGDHQRFV 518
Query: 445 SAF--TLDGWFKTGDTVVFKDGQYW-IRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITD 501
A+ G++ TGD +G Y+ I GR D+I G+++ E+E + HP++ +
Sbjct: 519 DAYFKAYPGYYFTGDGAYRTEGGYYQITGRMD-DVINISGHRLGTAEIEDAIADHPAVPE 577
Query: 502 VAVIGVPDMTWGQRVTAVVTLREGHSLSH---RELKEWARNVLAPYAVPSELVLVEEIPR 558
AVIG P G+ A + +++ S +ELK +A YAVP E+++V+ +P+
Sbjct: 578 SAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPK 637
Query: 559 NQMGKIDKKAL 569
+ GK+ ++ L
Sbjct: 638 TRSGKVMRRLL 648
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 89.7 bits (221), Expect = 6e-18
Identities = 111/444 (25%), Positives = 173/444 (38%), Gaps = 104/444 (23%)
Query: 78 LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
L Q C+ C ++ + N +++ + A + V VPLY + Y+
Sbjct: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
Query: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
I + S V+ Q+ + LL V RK G+ L+ P A+ G V
Sbjct: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
Query: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVH----K 229
+E + PVP Q + +++ +TSGTTG PKG + TH N+ A +G + +
Sbjct: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQ 332
Query: 230 WAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
WA T DV + LPL H+ + + G + + LS + +
Sbjct: 333 WAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
Query: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
+F VP + ++ YD+ F+Q P + L + K
Sbjct: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
Query: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
+R++V+G+A VL + G + E YG TE + T
Sbjct: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
Query: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
G VG PLP +++V E AC + EGE+ VRGP+VF
Sbjct: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
Query: 434 REYWNKPEETKSAFTLDGWFKTGD 457
+ Y P+ TK A DGW TGD
Sbjct: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 88.6 bits (218), Expect = 1e-17
Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)
Query: 95 EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
++ V N +++++ A + VAVPLY A + VICD+ Q +
Sbjct: 132 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 191
Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
+VL S + + L+ P K G+ +L L A G +E PVP
Sbjct: 192 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 249
Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
++I +TSGTTG PKG + THQNI A + + H + T DDV + LPL
Sbjct: 250 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 307
Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
H+ +V A++ C VG + P P ++++K +
Sbjct: 308 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 367
Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
+ F +AV + + +L + RH F ++ ++R++V+G+A + V
Sbjct: 368 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 427
Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
+ ++ G + E YG TE L G T+ G VG PL
Sbjct: 428 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 469
Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
AC+Y + D V EGE+ ++G +VF+ Y PE+T+ A DGW
Sbjct: 470 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 522
Query: 455 TGD 457
TGD
Sbjct: 523 TGD 525
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 88.6 bits (218), Expect = 1e-17
Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)
Query: 95 EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
++ V N +++++ A + VAVPLY A + VICD+ Q +
Sbjct: 132 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 191
Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
+VL S + + L+ P K G+ +L L A G +E PVP
Sbjct: 192 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 249
Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
++I +TSGTTG PKG + THQNI A + + H + T DDV + LPL
Sbjct: 250 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 307
Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
H+ +V A++ C VG + P P ++++K +
Sbjct: 308 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 367
Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
+ F +AV + + +L + RH F ++ ++R++V+G+A + V
Sbjct: 368 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 427
Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
+ ++ G + E YG TE L G T+ G VG PL
Sbjct: 428 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 469
Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
AC+Y + D V EGE+ ++G +VF+ Y PE+T+ A DGW
Sbjct: 470 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 522
Query: 455 TGD 457
TGD
Sbjct: 523 TGD 525
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 88.6 bits (218), Expect = 1e-17
Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)
Query: 95 EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
++ V N +++++ A + VAVPLY A + VICD+ Q +
Sbjct: 188 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 247
Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
+VL S + + L+ P K G+ +L L A G +E PVP
Sbjct: 248 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 305
Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
++I +TSGTTG PKG + THQNI A + + H + T DDV + LPL
Sbjct: 306 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 363
Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
H+ +V A++ C VG + P P ++++K +
Sbjct: 364 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 423
Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
+ F +AV + + +L + RH F ++ ++R++V+G+A + V
Sbjct: 424 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 483
Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
+ ++ G + E YG TE L G T+ G VG PL
Sbjct: 484 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 525
Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
AC+Y + D V EGE+ ++G +VF+ Y PE+T+ A DGW
Sbjct: 526 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 578
Query: 455 TGD 457
TGD
Sbjct: 579 TGD 581
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 87.8 bits (216), Expect = 2e-17
Identities = 110/444 (24%), Positives = 172/444 (38%), Gaps = 104/444 (23%)
Query: 78 LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
L Q C+ C ++ + N +++ + A + V VPLY + Y+
Sbjct: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
Query: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
I + S V+ Q+ + LL V RK G+ L+ P A+ G V
Sbjct: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
Query: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWT 233
+E + PVP Q + +++ +TSGTTG PKG + TH N+ A +G +
Sbjct: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKV 332
Query: 234 ----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
+DDV++ LPL H+ V + G + + LS + +
Sbjct: 333 IFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
Query: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
+F VP + ++ YD+ F+Q P + L + K
Sbjct: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
Query: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
+R++V+G+A VL + G + E YG TE + T
Sbjct: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
Query: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
G VG PLP +++V E AC + EGE+ VRGP+VF
Sbjct: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
Query: 434 REYWNKPEETKSAFTLDGWFKTGD 457
+ Y P+ TK A DGW TGD
Sbjct: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 86.7 bits (213), Expect = 5e-17
Identities = 137/542 (25%), Positives = 215/542 (39%), Gaps = 66/542 (12%)
Query: 64 GRHTYRELYSRSLRLSQEICRLCG-----CVGGDLREERVSFLCANDASYVVAQWASWMS 118
G T+ EL +R+ + + + G C G E + A+ A + W
Sbjct: 141 GSVTFGELDARACQAAWALKAELGDPASLCAG----EPTALLVLASQAVPALCMWLGLAK 196
Query: 119 GGVAVPLYRKHPAAQ-LEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPL------- 170
G H L + + S + V++ + E L ++ KL +
Sbjct: 197 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS 256
Query: 171 -TPAIYT--GAVEEPAEVPVPEQ-----GWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
TP + A++ PVP WR+ A+ IYTSGTTG PK + TH+ + +
Sbjct: 257 PTPGVGALGAALDAAPSHPVPADLRAGITWRSP-ALFIYTSGTTGLPKPAILTHERVLQM 315
Query: 223 VTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSS 282
L A T DDV+ VLPL+HV G+V +L L +GATCV+ P+FS W+
Sbjct: 316 SKMLSLSGA-TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWD---DC 371
Query: 283 ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEK 342
+ V + V +L+ Y QP + +RL + L V E
Sbjct: 372 RQHGVTVILYV----GELLRYLCNIPQQPEDR-------THTVRLAMGN--GLRADVWET 418
Query: 343 WKNITGH-TLLERYGMTEIGMAL---------SGPLTTAVRLPGSVGTPLPGVQVRIVSE 392
++ G + E YG TE M L G ++ +R+ +P VQ + +
Sbjct: 419 FQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRML----SPFELVQFDMEAA 474
Query: 393 NPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGW 452
P R+ + I E G +T ++ + RGP RE + + D +
Sbjct: 475 EPVRDNQGFCIPVGLGEPGLLLTK-VVSQQPFVGYRGP---RELSERKLVRNVRQSGDVY 530
Query: 453 FKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPD 509
+ TGD + ++G + R R D + G VS EVE L + V V G VP
Sbjct: 531 YNTGDVLAMDREGFLYFRDRLG-DTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589
Query: 510 MTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
G+ A V L G + +L + R L YA P + + + + K+ K L
Sbjct: 590 CE-GKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
Query: 570 IR 571
+R
Sbjct: 649 VR 650
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 84.7 bits (208), Expect = 2e-16
Identities = 122/466 (26%), Positives = 183/466 (39%), Gaps = 69/466 (14%)
Query: 146 VLASQEYLELLSP---VVRKLGVPLLPLTPAIYTGAV-----EEPAEVPVPEQGWRNKGA 197
++ + E+LE L P +R +G+ L P + + E AEV P G+ +
Sbjct: 265 LVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQ 324
Query: 198 MI------IYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVV 251
I I+TSGTTG PK +H I G ++DVI LPL+H+ G +
Sbjct: 325 SITDTCLYIFTSGTTGLPKAARISHLKILQC-QGFYQLCGVHQEDVIYLALPLYHMSGSL 383
Query: 252 NALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQP 311
++ + +GAT V+ +FS Q WE + R+ VF + + L+ QP
Sbjct: 384 LGIVGCMGIGATVVLKSKFSAGQFWE---DCQQHRVTVFQYIGELCRYLV-------NQP 433
Query: 312 HAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGH----TLLERYGMTEIGMALSGP 367
+ +A K+RL V GS P + W+ +LE YG+TE +A
Sbjct: 434 PS----KAERGHKVRLAV-GSGLRP----DTWERFVRRFGPLQVLETYGLTEGNVATIN- 483
Query: 368 LTTAVRLPGSVGT---------PLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGF 418
T R G+VG P ++ + + P R+ + + E G V P
Sbjct: 484 -YTGQR--GAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAP-- 538
Query: 419 EEKEGELLVRGPSVFREYWNKPEETKSAFTL------DGWFKTGDTVVFKDGQYWIRGRT 472
V S F Y PE + D +F TGD +V D +
Sbjct: 539 --------VSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDR 590
Query: 473 SVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVP-DMTWGQRVTAVVTLREGHSLSHR 531
+ D + G V+ EV A + +V V GV G+ A + LR H+L
Sbjct: 591 TGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLM 650
Query: 532 ELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHPS 576
+L L PYA P L L E + + K K + F PS
Sbjct: 651 QLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPS 696
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 81.6 bits (200), Expect = 2e-15
Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)
Query: 80 QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131
+++ L C+G L ++ + N +V+ + + V VPLY
Sbjct: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183
Query: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187
+ Y++ ++ S+V ++ LL V KL G+ ++ + A + VE V
Sbjct: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243
Query: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229
+ G N+ A+I +TSGTTG PKG + TH+NI + + V
Sbjct: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303
Query: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282
T DD ++ LPL H+ V CVM+ + ++ + L
Sbjct: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353
Query: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316
+ + VF VP + ++ +DR F Q + DF
Sbjct: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410
Query: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365
+++ ++RLMV+G+A + VL + G E YG TE G L+
Sbjct: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470
Query: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425
P G VG P+P +++V E +Y + AEG EGE+
Sbjct: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508
Query: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457
V+GP+VF+ Y P +T A DGW TGD
Sbjct: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 74.7 bits (182), Expect = 2e-13
Identities = 108/482 (22%), Positives = 188/482 (39%), Gaps = 59/482 (12%)
Query: 53 FGDRIALVDQHGRH----TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASY 108
FG AL ++G+ + + Y + ++ + +L G R V L N A +
Sbjct: 64 FGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKL-----GLERFHGVGILGFNSAEW 118
Query: 109 VVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLL 168
+ + ++GG+ V +Y + A +YVI ++ +++L + + L ++ L
Sbjct: 119 FITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVEND--QQLQKILSIPQSSLE 176
Query: 169 PLTPAI--------------YTGAVEEPAEVP------VPEQGWRNKGAMIIYTSGTTGR 208
PL I + +E +P V E N+ A++IYTSGTTG
Sbjct: 177 PLKAIIQYRLPMKKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTGI 236
Query: 209 PKGVLSTHQNIRAVVTGLVHKWAWT-KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMM 267
PKGV+ +H NI + + + T K + ++ LPL H+ + + P+ +GA
Sbjct: 237 PKGVMLSHDNITWIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFA 296
Query: 268 PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRL 327
+ + L P VF+ VP I+ K+ E ++ + V I
Sbjct: 297 QADALKGTLVSTLKEVKP--TVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGF 354
Query: 328 MVSGSAAL---PLPVLEKW-KNITGHTLLERYGMTEIGMALSG--PLT-TAVRLPGSVGT 380
V+ L PV + K + + G+ +SG PL S+
Sbjct: 355 KVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSLDI 414
Query: 381 PLPGVQVRIVSENPQREACSYTIHAEGDER---GTKVTPG-----FEEKE---GELLVRG 429
P+ + S P +TI + + R K+ G F++ + GE+ + G
Sbjct: 415 PIGELYGLSESSGP------HTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWG 468
Query: 430 PSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGGYKVSALE 488
+F Y ET A +GW +GD G ++ G +I GG V +
Sbjct: 469 RHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIP 528
Query: 489 VE 490
VE
Sbjct: 529 VE 530
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 71.6 bits (174), Expect = 2e-12
Identities = 120/511 (23%), Positives = 204/511 (39%), Gaps = 82/511 (16%)
Query: 53 FGDRIAL----VDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASY 108
+GD IAL D+ +Y + Y + R ++ +L G + V+ L N +
Sbjct: 116 YGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKL-----GLKQAHSVAILGFNSPEW 170
Query: 109 VVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLA-SQEYLELLSPVVRKL---- 163
+ + +GG+ +Y +Y+ D ++V++ +Q+ LE + + ++L
Sbjct: 171 FFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLK 230
Query: 164 GVPLLPLTPA-----IYTGAVEEPAEV--PVPEQGWR--------NKGAMIIYTSGTTGR 208
V + P +YT +EE E+ VPE+ N+ +++YTSGTTG
Sbjct: 231 AVVIYKEPPPNKMANVYT--MEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGN 288
Query: 209 PKGVLSTHQNIRAVV-----TGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPL-WVGA 262
PKGV+ + NI G + A + +V++ LPL H+ + L + W
Sbjct: 289 PKGVMLSQDNITWTARYGSQAGDIRP-AEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ 347
Query: 263 TCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLR---- 318
C P+ + E M VP ++ K+ME Q F+R
Sbjct: 348 VCFAEPDALKGSLVNTLREVEP---TSHMGVPRVWEKIMERIQEVAAQ---SGFIRRKML 401
Query: 319 ----AVCEEKIRLMVSGSAALPLP-------VLEKWKNITGHTLLER--YGMTEIGMALS 365
+V E+ L GS P VL K + G ++ YG + MA +
Sbjct: 402 LWAMSVTLEQ-NLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPM-MAET 459
Query: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFE------ 419
+ + G L +P +Y +++ G K+ PG
Sbjct: 460 QHFFLGLNIRLYAGYGLSETSGPHFMSSPY----NYRLYSSG-----KLVPGCRVKLVNQ 510
Query: 420 --EKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDI 476
E GE+ + G ++F Y N ++T A +GW TGD + DG +I GR I
Sbjct: 511 DAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELI 570
Query: 477 IKTGGYKVSALEVEWHL-LAHPSITDVAVIG 506
I GG V + +E + + P I++ +IG
Sbjct: 571 ITAGGENVPPVPIEEAVKMELPIISNAMLIG 601
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 71.2 bits (173), Expect = 2e-12
Identities = 101/393 (25%), Positives = 155/393 (39%), Gaps = 29/393 (7%)
Query: 187 VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHH 246
+P +G ++ IYTSGTTG PK + H + H + DV+ LPL+H
Sbjct: 235 IPSKGMDDR-LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYH 293
Query: 247 VHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDR 306
G + + L G T V+ +FS + W+ + V + I L++ R
Sbjct: 294 SAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKY---NCTVVQYIGEICRYLLKQPVR 350
Query: 307 HFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG 366
+ H ++RL V G+ P E + + E YG TE +++
Sbjct: 351 EAERRH-----------RVRLAV-GNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
Query: 367 PLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGDERGTKVTPGFEE 420
+ V G LP V +R+V N R+A I + E G V +
Sbjct: 399 -MDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG---QI 454
Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKDGQYWIRGRTSVDIIKT 479
+ + L R E + S F+ D + +GD +V + Y S D +
Sbjct: 455 NQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRW 514
Query: 480 GGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHS-LSHRELKEWAR 538
G VS EVE L TDVAV GV + + + + + HS L + + +
Sbjct: 515 RGENVSTTEVEGVLSRLLGQTDVAVYGVA-VPGVEGKAGMAAVADPHSLLDPNAIYQELQ 573
Query: 539 NVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
VLAPYA P L L+ ++ KI K L R
Sbjct: 574 KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 70.1 bits (170), Expect = 5e-12
Identities = 131/546 (23%), Positives = 219/546 (40%), Gaps = 75/546 (13%)
Query: 67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
TY ++ RS ++++ + G GD V+ L N+ +YV W + G A+
Sbjct: 80 TYAQVDRRSNQVARALHDHLGLRQGDC----VALLMGNEPAYVWL-WLGLVKLGCAMACL 134
Query: 127 RKHPAAQ-LEYVICDSQSSVVLASQEY---LELLSPVVRKLGVPLLPLTPAIYTGA---- 178
+ A+ L + + V+L S E +E + P ++K V + ++ T
Sbjct: 135 NYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSF 194
Query: 179 ---VEEPAEVPVPEQGWRNK-----GAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW 230
V+E + P+PE WR++ A+ IYTSGTTG PK + THQ I TGL
Sbjct: 195 LDKVDEVSTEPIPES-WRSEVTFSTPALYIYTSGTTGLPKAAMITHQRI-WYGTGLTFVS 252
Query: 231 AWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVF 290
DDVI LP +H ++ + + GAT + +FS Q W+ + + NV
Sbjct: 253 GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD-----DCRKYNV- 306
Query: 291 MAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKW-KNITGH 349
V +L+ Y +P+ +D K+RL + L V ++ K
Sbjct: 307 -TVIQYIGELLRYLCNSPQKPNDRD-------HKVRLALGN--GLRGDVWRQFVKRFGDI 356
Query: 350 TLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVS----------ENPQREAC 399
+ E Y TE + R G+VG + +Q +I++ + P R+
Sbjct: 357 CIYEFYAATEGNIG----FMNYARKVGAVGR-VNYLQKKIITYDLIKYDVEKDEPVRDEN 411
Query: 400 SYTIHAEGDERG------TKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWF 453
Y + E G T++TP F G R+ + K D +F
Sbjct: 412 GYCVRVPKGEVGLLVCKITQLTP-FNGYAGAKAQTEKKKLRDVFKKG---------DLYF 461
Query: 454 KTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPDMT 511
+GD ++ + D + G V+ EV + + +V V G VPD
Sbjct: 462 NSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE 521
Query: 512 WGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
G+ A + ++E H ++L + + L YA P L + + I K K L+
Sbjct: 522 -GRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 580
Query: 572 H-FHPS 576
F+P+
Sbjct: 581 EGFNPA 586
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 69.7 bits (169), Expect = 7e-12
Identities = 94/407 (23%), Positives = 160/407 (39%), Gaps = 83/407 (20%)
Query: 199 IIYTSGTTGRPKGVLST--------HQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGV 250
I+YTSGTTG PKGV+ H ++ ++ + W D+ V + +G
Sbjct: 296 ILYTSGTTGLPKGVIRPTGGYAVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYG- 354
Query: 251 VNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEY-YDRHFT 309
PL G T V+ E P TP + V L E+ FT
Sbjct: 355 ------PLLHGNTTVLY-EGKPVG---------TPDAGAYFRV------LAEHGVAALFT 392
Query: 310 QPHAQDFLRAVCEE-------------KIRLMVSGSAALPLPVLEKWKNITGHTLLERYG 356
P A +RA+ ++ + + + + LE KN+ +L+ +
Sbjct: 393 APTA---IRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHWW 449
Query: 357 MTEIGMALS----GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
TE G ++ G + PG G +PG V I+ +N Q+
Sbjct: 450 QTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCL---------- 499
Query: 413 KVTPGFEEKEGELLVR---GPSVFREYWNKPEETKSAF--TLDGWFKTGDT-VVFKDGQY 466
G ++V+ P F W E K + G++ T D + ++G
Sbjct: 500 ----------GNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYL 549
Query: 467 WIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGH 526
++ R D+I G+++SA +E +L+H ++ D AV+G D G A+ LR+
Sbjct: 550 YVMSRVD-DVINVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDI 608
Query: 527 SLSH----RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
+ + E+ + R + P A V V+++P+ + GKI + AL
Sbjct: 609 NATEEQVLEEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSAL 655
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 67.8 bits (164), Expect = 3e-11
Identities = 101/389 (25%), Positives = 156/389 (40%), Gaps = 64/389 (16%)
Query: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
A +++TSGTTG PK V H+ I + + T++DV+ PL VV L
Sbjct: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLA 252
Query: 257 PLWVGATCVMMP---EFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHA 313
L GA+ +++P + P ++ S R+ V A PT+ R +Q
Sbjct: 253 -LSSGASLLIVPTSVKLLPSKLASVLFSHH--RVTVLQATPTLLR-------RFGSQLIK 302
Query: 314 QDFLRAVCEEKIRLMVSGSAALP-LPVLEKWKNITGHT-LLERYGMTEIGM--------- 362
L A +R++ G A P L VL W+ T + YG+TE+
Sbjct: 303 STVLSATTS--LRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
Query: 363 -ALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEK 421
L+ T LP +G PL G V + R+ +TI +E
Sbjct: 361 KTLNS--TLKCELPVQLGFPLLGTVVEV------RDTNGFTI---------------QEG 397
Query: 422 EGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGG 481
G++ + G + R + E T T+ TGD V KDG+ + GR I + G
Sbjct: 398 SGQVFLGGRN--RVCFLDDEVTVPLGTMRA---TGDFVTVKDGEIFFLGRKDSQIKRHG- 451
Query: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWARNV 540
L +E L ++ + +TW Q + + + S+ KE +
Sbjct: 452 ---KRLNIE---LVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKE-LQKY 504
Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
L +AVP ELVL++ +P GKID L
Sbjct: 505 LPSHAVPDELVLIDSLPFTSHGKIDVSEL 533
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 67.4 bits (163), Expect = 3e-11
Identities = 76/348 (21%), Positives = 140/348 (40%), Gaps = 41/348 (11%)
Query: 65 RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
R ++ EL S S + + + C GD RV + + +A A +G V +P
Sbjct: 94 RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
+ + Y + S+++ ++ + ++L+P V + L +
Sbjct: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
Query: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
++ ++ + N+ I +TSGT+G PK TH + ++ W
Sbjct: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
Query: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
T DV+ + +++ P W+ CV +P F P + + S+ P I
Sbjct: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
Query: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
VF + PT+Y L+ Q+ + + + ++ VS + V EKW+N TG
Sbjct: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
Query: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQR 396
+ E YG TE + + G PGS+G P P V++ + +R
Sbjct: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRR 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,702,522
Number of Sequences: 37866
Number of extensions: 1133647
Number of successful extensions: 2382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2242
Number of HSP's gapped (non-prelim): 64
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.