Guide to the Human Genome
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Name: DYRK1A Sequence: fasta or formatted (540aa) NCBI GI: 18765754
Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 4

Referenced in:

Dual-Specificity Protein Kinases

Other entries for this name:
alt prot [584aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [754aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [529aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [763aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         28           2
 C cysteine            1.3          7           1
 D aspartate           5.9         32           3
 E glutamate           4.8         26           1
 F phenylalanine       3.9         21           2
 G glycine             5.9         32           2
 H histidine           3.5         19           1
 I isoleucine          5.2         28           2
 K lysine              7.4         40           3
 L leucine             8.9         48           2
 M methionine          3.7         20           1
 N asparagine          4.1         22           1
 P proline             5.0         27           2
 Q glutamine           5.9         32           2
 R arginine            5.6         30           2
 S serine              7.8         42           4
 T threonine           5.0         27           2
 V valine              5.6         30           2
 W tryptophan          0.9          5           1
 Y tyrosine            4.4         24           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   dual-specificity tyrosine-(Y)-phosphorylation regula... 
DYRK1A                0.951   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.951   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.951   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.928   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1B                0.656   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.599   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.583   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK4                 0.238   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK2                 0.234   dual-specificity tyrosine-(Y)-phosphorylation regul...
DYRK2                 0.234   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK3                 0.233   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK3                 0.233   dual-specificity tyrosine-(Y)-phosphorylation regula...
HIPK2                 0.183   homeodomain interacting protein kinase 2 isoform 2 ...
HIPK2                 0.183   homeodomain interacting protein kinase 2 isoform 1 ...
HIPK1                 0.182   homeodomain-interacting protein kinase 1 isoform 1 [...
HIPK1                 0.182   homeodomain-interacting protein kinase 1 isoform 2 [...
HIPK3                 0.177   homeodomain interacting protein kinase 3 isoform 2 ...
HIPK3                 0.177   homeodomain interacting protein kinase 3 isoform 1 ...
HIPK4                 0.163   homeodomain interacting protein kinase 4 
CLK1                  0.137   CDC-like kinase 1 isoform 2 
CLK1                  0.137   CDC-like kinase 1 isoform 1 
CLK4                  0.137   CDC-like kinase 4 
CLK2                  0.136   CDC-like kinase 2 
CLK3                  0.136   CDC-like kinase 3 isoform a 
CLK3                  0.136   CDC-like kinase 3 isoform b 
PRPF4B                0.134   serine/threonine-protein kinase PRP4K 
LOC653052             0.104   PREDICTED: similar to homeodomain interacting prote...
CDKL5                 0.101   cyclin-dependent kinase-like 5 
CDKL5                 0.101   cyclin-dependent kinase-like 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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