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Search of human proteins with 187608363
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 808 0.0
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 790 0.0
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 385 e-107
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 280 1e-75
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 277 1e-74
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 232 4e-61
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 96 4e-20
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 96 4e-20
gi|51593098 class-I MHC-restricted T cell associated molecule [H... 95 1e-19
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 94 3e-19
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 94 3e-19
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 87 3e-17
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 87 3e-17
gi|166295173 kin of IRRE like [Homo sapiens] 84 2e-16
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 83 5e-16
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 83 5e-16
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 83 5e-16
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 82 9e-16
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 82 1e-15
gi|157819143 IgLON family member 5 [Homo sapiens] 81 1e-15
gi|45594240 limbic system-associated membrane protein [Homo sapi... 81 2e-15
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 80 4e-15
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 77 4e-14
gi|68163411 activated leukocyte cell adhesion molecule [Homo sap... 76 5e-14
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 75 1e-13
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 74 2e-13
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 74 2e-13
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 73 5e-13
gi|110349719 titin isoform N2-A [Homo sapiens] 72 7e-13
gi|18426911 signal-regulatory protein alpha precursor [Homo sapi... 72 7e-13
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 808 bits (2086), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL 60
MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL
Sbjct: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL 60
Query: 61 QWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTA 120
QWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTA
Sbjct: 61 QWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTA 120
Query: 121 KSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQ 180
KSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQ
Sbjct: 121 KSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQ 180
Query: 181 EDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD 240
EDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD
Sbjct: 181 EDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD 240
Query: 241 PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 300
PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT
Sbjct: 241 PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 300
Query: 301 ATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKG 360
ATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKG
Sbjct: 301 ATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKG 360
Query: 361 TYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
TYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI
Sbjct: 361 TYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 790 bits (2041), Expect = 0.0
Identities = 398/432 (92%), Positives = 398/432 (92%), Gaps = 34/432 (7%)
Query: 1 MGAPAASLLLLLLLFACCWAPGGANLSQD------------------------------- 29
MGAPAASLLLLLLLFACCWAPGGANLSQD
Sbjct: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML 60
Query: 30 ---DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 86
DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV
Sbjct: 61 ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 120
Query: 87 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 146
TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD
Sbjct: 121 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 180
Query: 147 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 206
TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS
Sbjct: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
Query: 207 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 266
IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL
Sbjct: 241 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 300
Query: 267 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 326
WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS
Sbjct: 301 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 360
Query: 327 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 386
STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG
Sbjct: 361 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 420
Query: 387 QSGGDDKKEYFI 398
QSGGDDKKEYFI
Sbjct: 421 QSGGDDKKEYFI 432
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 385 bits (988), Expect = e-107
Identities = 195/409 (47%), Positives = 264/409 (64%), Gaps = 43/409 (10%)
Query: 33 PWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHE 92
P T + TVV GGT +L C+V ++++SLQWSNPAQQTLYF +K+ALRDNRI+LV ++ HE
Sbjct: 29 PLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHE 88
Query: 93 LSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNC 152
LSIS+S+V+L+DEG+YTCS+FTMPV+T+K+ +TVLG+P+KP I+G+ S + E D L C
Sbjct: 89 LSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTC 148
Query: 153 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
++SGSKPAA + W K D+E+ +ED N KTFTVSS++ F+V R DDG +++C V+
Sbjct: 149 KTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVD 208
Query: 213 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 272
HESL + Q +E+ YTP+ I P P P+EGQ L+L CE +G P+P+ LW K+G
Sbjct: 209 HESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGG 268
Query: 273 V---PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL--------------- 314
P + L FLNK+D+GTY C AT+ +G A Y L
Sbjct: 269 ELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLLPTTII 328
Query: 315 -------------------------NVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIMLI 349
++ DP+ + + HA+IGGIVA +VF+ L +
Sbjct: 329 PSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVTLCSIF 388
Query: 350 FLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
LG YL RHKGTYLT+EAKG++DAPDADTAIINAEG Q ++KKEYFI
Sbjct: 389 LLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 280 bits (717), Expect = 1e-75
Identities = 163/402 (40%), Positives = 233/402 (57%), Gaps = 16/402 (3%)
Query: 4 PAASLLLLLLLF-ACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQW 62
P L LLLLLF A P G D +T D TV+ G + CQV +DS +Q
Sbjct: 22 PGLRLRLLLLLFSAAALIPTG-----DGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQL 76
Query: 63 SNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKS 122
NP +QT+YF + R L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + +
Sbjct: 77 LNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT 136
Query: 123 LVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 182
+TVL P+ +I K + E + +NC + SKPA + W KG+ EL G+ + ++E
Sbjct: 137 TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEW 195
Query: 183 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP 242
+ +TV+S + +V +EDDG ++C V H ++ G + T + +EV Y P I+ P
Sbjct: 196 SD--MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYP 252
Query: 243 ---HPREGQKLLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYG 298
REG L L CE G P P W + + +P + L LNK+D+GTY
Sbjct: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
Query: 299 CTATSNMGSYKAYYTLNVNDPSPVPSSS--STYHAIIGGIVAFIVFLLLIMLIFLGHYLI 356
C A++ +G + Y L V D S + HA+IGG+VA +VF +L +LI LG Y
Sbjct: 313 CEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFA 372
Query: 357 RHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
RHKGTY THEAKG+DDA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 373 RHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 277 bits (708), Expect = 1e-74
Identities = 166/430 (38%), Positives = 239/430 (55%), Gaps = 44/430 (10%)
Query: 4 PAASLLLLLLLF-ACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQW 62
P L LLLLLF A P G D +T D TV+ G + CQV +DS +Q
Sbjct: 22 PGLRLRLLLLLFSAAALIPTG-----DGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQL 76
Query: 63 SNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKS 122
NP +QT+YF + R L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + +
Sbjct: 77 LNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT 136
Query: 123 LVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 182
+TVL P+ +I K + E + +NC + SKPA + W KG+ EL G+ + ++E
Sbjct: 137 TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEW 195
Query: 183 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP 242
+ +TV+S + +V +EDDG ++C V H ++ G + T + +EV Y P I+ P
Sbjct: 196 SD--MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYP 252
Query: 243 ---HPREGQKLLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYG 298
REG L L CE G P P W + + +P + L LNK+D+GTY
Sbjct: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
Query: 299 CTATSNMGSYKAYYTLNVNDPS---PVPSSSSTY-------------------------- 329
C A++ +G + Y L V DP P P++++T
Sbjct: 313 CEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAV 372
Query: 330 -HAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQS 388
HA+IGG+VA +VF +L +LI LG Y RHKGTY THEAKG+DDA DADTAIINAEGGQ+
Sbjct: 373 DHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQN 432
Query: 389 GGDDKKEYFI 398
++KKEYFI
Sbjct: 433 NSEEKKEYFI 442
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 232 bits (592), Expect = 4e-61
Identities = 141/391 (36%), Positives = 212/391 (54%), Gaps = 16/391 (4%)
Query: 11 LLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTL 70
LLLL+A PG Q T + TV GG + C++ ++ S + NPA+QTL
Sbjct: 11 LLLLWAAAAGPGAGQEVQ------TENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTL 64
Query: 71 YFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIP 130
+F RAL+D R QL +P + I +S+ L DEG Y C ++T + +TVL P
Sbjct: 65 FFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAP 124
Query: 131 QKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTV 190
+ P++ + ++ E L+C S+PAA L W + +EL G + NGK ++V
Sbjct: 125 ENPVVEVREQAV-EGGEVELSCLVPRSRPAATLRWYRDRKELKGVSS---SQENGKVWSV 180
Query: 191 SSSVTFQVTREDDGASIVCSVNHESL-KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQK 249
+S+V F+V R+DDG I+C +++L G + T ++V Y+PTA I REG
Sbjct: 181 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT 240
Query: 250 LLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSY 308
L+L C GNP P Q W + S+P L P L +D+GTY C A++ G
Sbjct: 241 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA 300
Query: 309 KAYYTLNVNDP-SPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEA 367
+A Y L V DP + V + +S +AI+GGI+A +VFL++ +L+ + +R KG+YLTHEA
Sbjct: 301 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA 360
Query: 368 KGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
G D+ +A A +N G G K+E+FI
Sbjct: 361 SGLDEQGEAREAFLN---GSDGHKRKEEFFI 388
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 96.3 bits (238), Expect = 4e-20
Identities = 102/370 (27%), Positives = 155/370 (41%), Gaps = 45/370 (12%)
Query: 5 AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54
AA LLL+ L W P P T D V A G +V L C QV +
Sbjct: 7 AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
Query: 55 HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101
E S L W+ + Q + E + L +L S+ + +
Sbjct: 56 MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
Query: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159
+ DEG YTC T P + ++S+ L + KP T K L + C S+G +P
Sbjct: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
Query: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
A++TW +L G P Q T TV+S + + DG ++ C V HES +
Sbjct: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276
T + V Y P I + GQ + L C+ R NP P Y W G +PP
Sbjct: 231 PQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
Query: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGI 336
+ Q + L+ ++K + T C T+ +G+ +A T+ V + P S + +AII +
Sbjct: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLV 349
Query: 337 VAFIVFLLLI 346
+ +VFL+L+
Sbjct: 350 LGILVFLILL 359
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 96.3 bits (238), Expect = 4e-20
Identities = 102/370 (27%), Positives = 155/370 (41%), Gaps = 45/370 (12%)
Query: 5 AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54
AA LLL+ L W P P T D V A G +V L C QV +
Sbjct: 7 AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
Query: 55 HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101
E S L W+ + Q + E + L +L S+ + +
Sbjct: 56 MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
Query: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159
+ DEG YTC T P + ++S+ L + KP T K L + C S+G +P
Sbjct: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
Query: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
A++TW +L G P Q T TV+S + + DG ++ C V HES +
Sbjct: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276
T + V Y P I + GQ + L C+ R NP P Y W G +PP
Sbjct: 231 PQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
Query: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGI 336
+ Q + L+ ++K + T C T+ +G+ +A T+ V + P S + +AII +
Sbjct: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLV 349
Query: 337 VAFIVFLLLI 346
+ +VFL+L+
Sbjct: 350 LGILVFLILL 359
>gi|51593098 class-I MHC-restricted T cell associated molecule [Homo
sapiens]
Length = 393
Score = 95.1 bits (235), Expect = 1e-19
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 7/201 (3%)
Query: 35 TSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELS 94
T TV G T+ LKC ++SSLQW P+ T++ E AL++++ QL+ + ++LS
Sbjct: 23 TETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLS 82
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE---KDTATLN 151
I++ NV L DEG Y C ++ V T + V VL P KPI+ S +R+ ++ L
Sbjct: 83 ITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEA--SVIRKQNGEEHVVLM 140
Query: 152 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSV 211
C + SKP ++TW G+ T + + +GK +S++ ++ +++ C +
Sbjct: 141 CSTMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKN--STVDCII 198
Query: 212 NHESLKGADRSTSQRIEVLYT 232
H L+G R E L T
Sbjct: 199 RHRGLQGRKLVAPFRFEDLVT 219
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 93.6 bits (231), Expect = 3e-19
Identities = 65/240 (27%), Positives = 106/240 (44%), Gaps = 8/240 (3%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST--PHELS 94
D+ VV+G V L C + ++ D + W + L G R L LV E
Sbjct: 56 DQVVVSGQPVTLLCAIPEY-DGFVLW---IKDGLALGVGRDLSSYPQYLVVGNHLSGEHH 111
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 153
+ I L D+ Y C +R+ + +TVL P P+I G SLR D L C
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCH 171
Query: 154 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNH 213
+ +KPAA + W + + ++G +GK ++ S++ ++G SIVC +
Sbjct: 172 ADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATN 231
Query: 214 ESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 273
+++ G + TS I++ + P + +P E + HC + NP QY W K G +
Sbjct: 232 KAIPGG-KETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQI 290
Score = 30.0 bits (66), Expect = 3.8
Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 23/186 (12%)
Query: 184 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 243
+G + ++T + R++D VC + +R + + P + H
Sbjct: 373 SGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVN---GPPIISSTQTQH 429
Query: 244 PREGQKLLLHCEGRGNPVPQQYLWEKEGSV----------PPLKMTQE---SALIFPFLN 290
G+K + C R P P + W + +V T+E S L +
Sbjct: 430 ALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
Query: 291 KSDSGT-YGCTATSNMGSYKAYYTL-----NVNDPSPVPSSSSTYHAIIG-GIVAFIVFL 343
++D T Y CTA ++ GS L + + + + S IIG + A + FL
Sbjct: 490 RADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFL 549
Query: 344 LLIMLI 349
+L+ I
Sbjct: 550 VLMATI 555
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 93.6 bits (231), Expect = 3e-19
Identities = 65/240 (27%), Positives = 106/240 (44%), Gaps = 8/240 (3%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST--PHELS 94
D+ VV+G V L C + ++ D + W + L G R L LV E
Sbjct: 56 DQVVVSGQPVTLLCAIPEY-DGFVLW---IKDGLALGVGRDLSSYPQYLVVGNHLSGEHH 111
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 153
+ I L D+ Y C +R+ + +TVL P P+I G SLR D L C
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCH 171
Query: 154 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNH 213
+ +KPAA + W + + ++G +GK ++ S++ ++G SIVC +
Sbjct: 172 ADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATN 231
Query: 214 ESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 273
+++ G + TS I++ + P + +P E + HC + NP QY W K G +
Sbjct: 232 KAIPGG-KETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQI 290
Score = 30.0 bits (66), Expect = 3.8
Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 23/186 (12%)
Query: 184 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 243
+G + ++T + R++D VC + +R + + P + H
Sbjct: 373 SGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVN---GPPIISSTQTQH 429
Query: 244 PREGQKLLLHCEGRGNPVPQQYLWEKEGSV----------PPLKMTQE---SALIFPFLN 290
G+K + C R P P + W + +V T+E S L +
Sbjct: 430 ALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
Query: 291 KSDSGT-YGCTATSNMGSYKAYYTL-----NVNDPSPVPSSSSTYHAIIG-GIVAFIVFL 343
++D T Y CTA ++ GS L + + + + S IIG + A + FL
Sbjct: 490 RADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFL 549
Query: 344 LLIMLI 349
+L+ I
Sbjct: 550 VLMATI 555
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 86.7 bits (213), Expect = 3e-17
Identities = 98/355 (27%), Positives = 144/355 (40%), Gaps = 46/355 (12%)
Query: 5 AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54
AA LLL+ L W P P T D V A G +V L C QV +
Sbjct: 7 AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
Query: 55 HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101
E S L W+ + Q + E + L +L S+ + +
Sbjct: 56 MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
Query: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159
+ DEG YTC T P + ++S+ L + KP T K L + C S+G +P
Sbjct: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
Query: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
A++TW +L G P Q T TV+S + + DG ++ C V HES +
Sbjct: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276
T + V Y P I + GQ + L C+ R NP P Y W G +PP
Sbjct: 231 PQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
Query: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHA 331
+ Q + L+ ++K + T C T+ +G+ +A T+ V + P S T HA
Sbjct: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE-GPPSEHSGTEHA 343
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 86.7 bits (213), Expect = 3e-17
Identities = 82/350 (23%), Positives = 136/350 (38%), Gaps = 37/350 (10%)
Query: 9 LLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--GGTVVLKCQVKDHEDSSLQWSNPA 66
L +LL CC P Q PW + + ++ G T VL+C ++D W N +
Sbjct: 17 LAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGA-WLNRS 75
Query: 67 QQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTV 126
G+K ++ D R+ + T + S+ I NV + D+G YTCS+ T +
Sbjct: 76 SIIFAGGDKWSV-DPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLT 134
Query: 127 LGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGK 186
+ +P K ++ E TL C ++G KP ++WR P+ K
Sbjct: 135 VQVPPKIYDISNDMTVNEGTNVTLTCLATG-KPEPSISWR-------------HISPSAK 180
Query: 187 TFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAM-IRPDPPHPR 245
F + D CS ++ R ++ V + PT I+ P
Sbjct: 181 PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKV--KVVVNFAPTIQEIKSGTVTP- 237
Query: 246 EGQKLLLHCEGRGNPVP-------QQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYG 298
G+ L+ CEG G P P ++ L+ + + + S L + + G Y
Sbjct: 238 -GRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYT 296
Query: 299 CTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIML 348
C A + +G+ A LN P S++ Y V F + L++ L
Sbjct: 297 CVAANKLGTTNASLPLN-------PPSTAQYGITGSADVLFSCWYLVLTL 339
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 84.3 bits (207), Expect = 2e-16
Identities = 69/268 (25%), Positives = 124/268 (46%), Gaps = 12/268 (4%)
Query: 7 SLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPA 66
SLL+ +L + ++ G +Q +D+TVVAG VL C + ++ +QW+
Sbjct: 3 SLLVWILTLSDTFSQG----TQTRFSQEPADQTVVAGQRAVLPCVLLNYS-GIVQWTKDG 57
Query: 67 QQTLYFGEKRALRD-NRIQLVTSTPH-ELSISISNVALADEGEYTCSIFTMPVRTAKSLV 124
L G + L+ R ++V S + ++ I++ L+D+ Y C +R+ ++ +
Sbjct: 58 ---LALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKL 114
Query: 125 TVLGIPQKPIITGYKSSLREKDTA-TLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDP 183
TVL P+ I G L + T L C++ +KPAA + W + + G +
Sbjct: 115 TVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLK 174
Query: 184 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 243
+GK T S + T D G C +E++ + TS ++V + PT + +P
Sbjct: 175 DGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSG-KETSIELDVHHPPTVTLSIEPQT 233
Query: 244 PREGQKLLLHCEGRGNPVPQQYLWEKEG 271
+EG++++ C+ NP Y W K G
Sbjct: 234 VQEGERVVFTCQATANPEILGYRWAKGG 261
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 30/307 (9%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWS-NPAQQTLYF--GEKRALRDNRIQLVTSTPHEL 93
++T + GG V+L H + ++ PA ++F G ++ +L+ E
Sbjct: 121 EDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRET 180
Query: 94 SIS--ISNVALADEGE-YTCSIFTMPVRTAKSLVTVLGIPQKPIITGY--KSSLREKDTA 148
++S + N D G +TC + + K L + P +T +++E +
Sbjct: 181 TVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERV 240
Query: 149 TLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIV 208
CQ++ + W KG + ED + + + +F +
Sbjct: 241 VFTCQATANPEILGYRWAKGGFLI--------EDAHESRYETNVDYSFFTE------PVS 286
Query: 209 CSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWE 268
C V++ K + S + V + P ++ P P G + L C GNP P W
Sbjct: 287 CEVHN---KVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNP-PLTLTWT 342
Query: 269 KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTA-TSNMGSYKAYYTLNVNDPSPVPSSSS 327
K+ S + ++ + L+ + ++D+GTY C A +G + L VN P P+ SS +
Sbjct: 343 KKDS--NMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGP-PIISSEA 399
Query: 328 TYHAIIG 334
+A+ G
Sbjct: 400 VQYAVRG 406
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 82.8 bits (203), Expect = 5e-16
Identities = 67/254 (26%), Positives = 113/254 (44%), Gaps = 9/254 (3%)
Query: 92 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 149
+ ++++ + + DEG YTC T P + + + T L + KP K + + T
Sbjct: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
Query: 150 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 209
C S +P AR++W + + T++ G T TV+S T + DG ++ C
Sbjct: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
Query: 210 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 268
V HES + + V Y P I + G+ L C+ R NP P Y W
Sbjct: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
Query: 269 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327
G+ P + Q S L+ ++ + T+ CT T+ +G +A + V + +P + +
Sbjct: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPNTAGAG 356
Query: 328 TYHAIIGGIVAFIV 341
IIGGI+A I+
Sbjct: 357 ATGGIIGGIIAAII 370
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 82.8 bits (203), Expect = 5e-16
Identities = 94/351 (26%), Positives = 142/351 (40%), Gaps = 45/351 (12%)
Query: 5 AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54
AA LLL+ L W P P T D V A G +V L C QV +
Sbjct: 7 AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
Query: 55 HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101
E S L W+ + Q + E + L +L S+ + +
Sbjct: 56 MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
Query: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159
+ DEG YTC T P + ++S+ L + KP T K L + C S+G +P
Sbjct: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
Query: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
A++TW +L G P Q T TV+S + + DG ++ C V HES +
Sbjct: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276
T + V Y P I + GQ + L C+ R NP P Y W G +PP
Sbjct: 231 PQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
Query: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327
+ Q + L+ ++K + T C T+ +G+ +A T+ V +S++
Sbjct: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEHASASAN 340
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 82.8 bits (203), Expect = 5e-16
Identities = 104/394 (26%), Positives = 159/394 (40%), Gaps = 45/394 (11%)
Query: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL 60
M P A LLLLLLL + L D TVV G L C + DS
Sbjct: 9 MWGPEAWLLLLLLLASFTGRCPAGELETSDVV------TVVLGQDAKLPCFYRG--DSGE 60
Query: 61 QWSNPAQQTLYFGE---KRALRDNRIQLVTS--------------TPHELSISISNVALA 103
Q A + GE + AL ++ L S P + S+ + N A
Sbjct: 61 QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA 120
Query: 104 DEGEYTCSIFTMPVRT--AKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAA 161
DEGEY C + T P + A+ + VL P + G + T +C + GS PA
Sbjct: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGS-PAP 179
Query: 162 RLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADR 221
+TW D E+ G T + + ++ V+S +R +G + C V+H L D+
Sbjct: 180 SVTW---DTEVKGT-TSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL-QDQ 234
Query: 222 STSQRIEVLYTPTAMIRPDPPHP-----REGQKLLLHCEGRGNPVPQQYLWEK-EGSVPP 275
+ + V + A +R REG +L C G P P Y W + +G +P
Sbjct: 235 RITHILHVSFLAEASVRGLEDQNLWHIGREGA--MLKCLSEGQP-PPSYNWTRLDGPLPS 291
Query: 276 LKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP---SPVPSSSSTYHAI 332
L FP L SG Y C ++ S + T++V DP S + +
Sbjct: 292 GVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV 351
Query: 333 IGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHE 366
+ G++A ++F LL++++ L R K +T +
Sbjct: 352 VVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 82.0 bits (201), Expect = 9e-16
Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 22/283 (7%)
Query: 82 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 139
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
Query: 140 SSLREKD-----TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 192
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
Query: 193 SVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLL 251
+RE S+ C VN+ + + T + V Y P I D + +
Sbjct: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLT---LNVQYEPEVTIEGFDGNWYLQRMDVK 266
Query: 252 LHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYK 309
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 267 LTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRS 326
Query: 310 AYYTLNVND-PSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFL 351
+N+ + P P S + G + F++ + ++ + FL
Sbjct: 327 GQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFFL 369
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/333 (26%), Positives = 142/333 (42%), Gaps = 29/333 (8%)
Query: 4 PAASLLLLLLLFA-CCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHED-SSLQ 61
P LL LLLF+ C A G + + T V G V LKC ++ +E + +
Sbjct: 38 PLLLLLFPLLLFSRLCGALAGPIIVEPHV-------TAVWGKNVSLKCLIEVNETITQIS 90
Query: 62 WSN---PAQQTL------YFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSI 112
W + QT+ Y + R+ + ++ +I++ N+ +D G+Y C
Sbjct: 91 WEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKA 150
Query: 113 FTMPVRTAKS--LVTVLGIPQKPIITGYKSSL-REKDTATLNCQSSGSKPAARLTWRKGD 169
T P+ A+S VTVL P +I G S + +T C ++ KP A + W
Sbjct: 151 VTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDL 210
Query: 170 QELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEV 229
E+ T PN +T T+ S TR G I C V H +L+ D S +++
Sbjct: 211 GEMESTTTSF---PN-ETATIISQYKLFPTRFARGRRITCVVKHPALE-KDIRYSFILDI 265
Query: 230 LYTPTAMIRPDPPHPREGQK-LLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFP 287
Y P + + G+K + L C NP P + +W + +G P + ++ L F
Sbjct: 266 QYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFV 325
Query: 288 F-LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
L + SG Y C T+++G + ++DP
Sbjct: 326 HPLTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 81.3 bits (199), Expect = 1e-15
Identities = 74/281 (26%), Positives = 113/281 (40%), Gaps = 30/281 (10%)
Query: 39 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 98
TV G L C + +H + + W N + LY G R D R++L+ +TP E SI I+
Sbjct: 43 TVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSILIT 100
Query: 99 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 158
V L DEG YTCS T + ++ +P + + ++ E L C + G +
Sbjct: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG-R 159
Query: 159 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
P +TWR+ E G+ +S Q + V H +
Sbjct: 160 PEPTVTWRQLRDGFTSE---------GEILEISDIQRGQAGEYE-------CVTHNGVNS 203
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE------GS 272
A S + V Y PT + G+ LL CE P P + W K+ G+
Sbjct: 204 APDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVP-PADFQWYKDDRLLSSGT 261
Query: 273 VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKA 310
LK+ E S L+F ++ G Y C A + +G+ A
Sbjct: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 80.9 bits (198), Expect = 2e-15
Identities = 81/318 (25%), Positives = 133/318 (41%), Gaps = 26/318 (8%)
Query: 4 PAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWS 63
P L L+LL C P G + D T + TV G T +L+C V+D ++S + W
Sbjct: 7 PDRKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVED-KNSKVAWL 65
Query: 64 NPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSL 123
N + ++ G + D R++L E S+ I V + DEG YTCS+ T +
Sbjct: 66 NRSG-IIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQV 124
Query: 124 VTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDP 183
++ +P K ++ E TL C ++G +P +TWR H PT + +
Sbjct: 125 YLIVQVPPKISNISSDVTVNEGSNVTLVCMANG-RPEPVITWR------HLTPTGREFEG 177
Query: 184 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 243
+ + +TRE G C +E + AD ++ V Y PT +
Sbjct: 178 EEEYLEI-----LGITREQSG-KYECKAANE-VSSAD-VKQVKVTVNYPPT-ITESKSNE 228
Query: 244 PREGQKLLLHCEGRGNPVPQQYLWEKE------GSVPPLKMTQ-ESALIFPFLNKSDSGT 296
G++ L CE P P + W ++ + +K T+ +S+L + + G
Sbjct: 229 ATTGRQASLKCEASAVPAP-DFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGN 287
Query: 297 YGCTATSNMGSYKAYYTL 314
Y C A + +G A L
Sbjct: 288 YTCVAANKLGVTNASLVL 305
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 79.7 bits (195), Expect = 4e-15
Identities = 88/306 (28%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 82 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 139
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
Query: 140 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 192
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
Query: 193 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 250
+RE S+ C VN+ DR S + V Y P I D + +
Sbjct: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265
Query: 251 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 308
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
Query: 309 KAYYTLNVND----PSPVP---SSSSTYHAIIGGIVAFIVFLLLI---MLIFLGHYLIRH 358
+N+ + PSP + AIIGG+ I+ +L++ +++ L
Sbjct: 326 SGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTF 385
Query: 359 KGTYLT 364
KG Y T
Sbjct: 386 KGDYST 391
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 76.6 bits (187), Expect = 4e-14
Identities = 68/270 (25%), Positives = 116/270 (42%), Gaps = 9/270 (3%)
Query: 92 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 149
+ ++++ + + DEG YTC T P + + + T L + KP K + + T
Sbjct: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
Query: 150 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 209
C S +P AR++W + + T++ G T TV+S T + DG ++ C
Sbjct: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
Query: 210 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 268
V HES + + V Y P I + G+ L C+ R NP P Y W
Sbjct: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
Query: 269 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327
G+ P + Q S L+ ++ + T+ CT T+ +G +A + V + +P S
Sbjct: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPRASPRD 356
Query: 328 TYHAIIGGIVAFIVFLLLIMLIFLGHYLIR 357
+ G + ++ LLL+ L L+R
Sbjct: 357 VGPLVWGAVGGTLLVLLLLAGGSLAFILLR 386
>gi|68163411 activated leukocyte cell adhesion molecule [Homo
sapiens]
Length = 583
Score = 76.3 bits (186), Expect = 5e-14
Identities = 74/327 (22%), Positives = 136/327 (41%), Gaps = 45/327 (13%)
Query: 2 GAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVK-------- 53
GA + LL LL+ A + PG W + + G T+++ C++
Sbjct: 5 GASSCRLLFCLLISATVFRPGLG---------WYTVNSAY-GDTIIIPCRLDVPQNLMFG 54
Query: 54 -------DHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEG 106
D + + + ++++ + + +D R+ L ++SISN ++DE
Sbjct: 55 KWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKD-RLNL----SENYTLSISNARISDEK 109
Query: 107 EYTCSIFTMP-VRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL-NCQSSGSKPAARLT 164
+ C + T V A ++V V P KP I L + L +C S S P +T
Sbjct: 110 RFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNIT 169
Query: 165 WRKGDQELHGEPTRI------QEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
W + + LH + + DP + +T++S++ ++ T+ D CSV + G
Sbjct: 170 WYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSG 229
Query: 219 ADRSTS-QRIEVLYTPTAMIR----PDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 273
S Q + +Y PT + P +EG + L C G GNP P+++L+ G
Sbjct: 230 QKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQ- 288
Query: 274 PPLKMTQESALIFPFLNKSDSGTYGCT 300
P + + + ++ +G Y C+
Sbjct: 289 -PEGIRSSNTYTLTDVRRNATGDYKCS 314
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 75.1 bits (183), Expect = 1e-13
Identities = 81/310 (26%), Positives = 137/310 (44%), Gaps = 31/310 (10%)
Query: 16 ACCWAPGGANLSQDDSQPWTSDE-TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGE 74
A + PG S D + P D TV G + L+C + D + + W N + LY G
Sbjct: 15 ALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGN 72
Query: 75 KRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI 134
+ D R+ ++ +TP + SI I NV + DEG YTCS+ T + ++ +P + +
Sbjct: 73 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 132
Query: 135 ITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSV 194
++ E + TL C + G +P +TWR ++E G+ F VS
Sbjct: 133 NISSDITVNEGSSVTLLCLAIG-RPEPTVTWRH---------LSVKE---GQGF-VSEDE 178
Query: 195 TFQVT--REDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLL 252
+++ + D CS ++ R +I V Y P + + GQK +L
Sbjct: 179 YLEISDIKRDQSGEYECSALNDVAAPDVRKV--KITVNYPPY-ISKAKNTGVSVGQKGIL 235
Query: 253 HCEGRGNPVPQQYLWEKEGS-----VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSN 304
CE P+ + + W KE + + +++ + S L F +++ D G Y C AT+
Sbjct: 236 SCEASAVPMAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNK 294
Query: 305 MGSYKAYYTL 314
+G+ A TL
Sbjct: 295 LGNTNASITL 304
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 74.3 bits (181), Expect = 2e-13
Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 23/238 (9%)
Query: 97 ISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQKPIITGYKSS-LREKDTATLNC 152
I N+ + + G YTC RT + +TV P KP IT S+ + ++D L C
Sbjct: 286 IPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTC 345
Query: 153 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
+ W +Q L P R+Q + +T T+ S VTR D G C +
Sbjct: 346 EPEIQN--TTYLWWVNNQSLPVSP-RLQLSNDNRTLTLLS-----VTRNDVG-PYECGIQ 396
Query: 213 HESLKGADRSTSQRIEVLYTP-TAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG 271
++ D S + VLY P I P + R G L L C NP P QY W +G
Sbjct: 397 NK--LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNP-PAQYSWLIDG 453
Query: 272 SVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYK--AYYTLNVNDPSPVPSSSS 327
++ + TQE L + + +SG Y C A ++ + T+ V+ P PS SS
Sbjct: 454 NIQ--QHTQE--LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISS 507
Score = 73.9 bits (180), Expect = 2e-13
Identities = 76/256 (29%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 91 HELSISISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQKPIITGYKSS-LREKD 146
H + ISN+ + G YTC RT +TV KP I+ S + +KD
Sbjct: 458 HTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKD 517
Query: 147 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 206
C+ L W G Q L P R+Q +T T+ F VTR +D +
Sbjct: 518 AVAFTCEPEAQN-TTYLWWVNG-QSLPVSP-RLQLSNGNRTLTL-----FNVTR-NDARA 568
Query: 207 IVCSVNHESLKGADRSTSQRIEVLYTP-TAMIRPDPPHPREGQKLLLHCEGRGNPVPQQY 265
VC + + A+RS ++VLY P T +I P G L L C NP P QY
Sbjct: 569 YVCGIQNSV--SANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSP-QY 625
Query: 266 LWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGC----TATSNMGSYKAYYTLNVNDPSP 321
W G P + TQ L + +++GTY C AT S T++ + SP
Sbjct: 626 SWRINGI--PQQHTQ--VLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
Query: 322 VPSSSSTYHAIIGGIV 337
S+ +T +IG +V
Sbjct: 682 GLSAGATVGIMIGVLV 697
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 73.9 bits (180), Expect = 2e-13
Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 28/306 (9%)
Query: 14 LFACCWAPGGANLSQDDSQPWTSDE-TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYF 72
L A C G S D + P D TV G + L+C + D+ + + W N + LY
Sbjct: 20 LAALCLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTI-DNRVTRVAWLNRST-ILYA 77
Query: 73 GEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQK 132
G + D R+ L+++T + SI I NV + DEG YTCS+ T + ++ + K
Sbjct: 78 GNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPK 137
Query: 133 PIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSS 192
+ S+ E + +L C ++G +P +TWR H P + + +
Sbjct: 138 IVEISSDISINEGNNISLTCIATG-RPEPTVTWR------HISPKAVGFVSEDEYLEIQG 190
Query: 193 SVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLL 252
+TRE G CS +++ R ++ V Y P P GQK L
Sbjct: 191 -----ITREQSG-DYECSASNDVAAPVVRRV--KVTVNYPPYISEAKGTGVP-VGQKGTL 241
Query: 253 HCEGRGNPVPQQYLWEKEG--------SVPPLKMTQESALIFPFLNKSDSGTYGCTATSN 304
CE P ++ W K+ V S LIF +++ D G Y C A++
Sbjct: 242 QCEASAVP-SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNK 300
Query: 305 MGSYKA 310
+G A
Sbjct: 301 LGHTNA 306
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 72.8 bits (177), Expect = 5e-13
Identities = 78/299 (26%), Positives = 133/299 (44%), Gaps = 31/299 (10%)
Query: 27 SQDDSQPWTSDE-TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQL 85
S D + P D TV G + L+C + D + + W N + LY G + D R+ +
Sbjct: 33 SGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGNDKWSIDPRVII 90
Query: 86 VTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK 145
+ +TP + SI I NV + DEG YTCS+ T + ++ +P + + ++ E
Sbjct: 91 LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
Query: 146 DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVT--REDD 203
+ TL C + G +P +TWR ++E G+ F VS +++ + D
Sbjct: 151 SSVTLLCLAIG-RPEPTVTWRH---------LSVKE---GQGF-VSEDEYLEISDIKRDQ 196
Query: 204 GASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQ 263
CS ++ R +I V Y P + + GQK +L CE P+ +
Sbjct: 197 SGEYECSALNDVAAPDVRKV--KITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAE 253
Query: 264 QYLWEKEGS-----VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL 314
+ W KE + + +++ + S L F +++ D G Y C AT+ +G+ A TL
Sbjct: 254 -FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 72.4 bits (176), Expect = 7e-13
Identities = 78/316 (24%), Positives = 129/316 (40%), Gaps = 29/316 (9%)
Query: 30 DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST 89
D +P + D V+AG + +C V + + WS + E R + I V +T
Sbjct: 6274 DIKPVSID--VIAGESADFECHVTGAQPMRITWSKDNK------EIRPGGNYTITCVGNT 6325
Query: 90 PHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSL-REKDTA 148
PH + I V D G+YTC + S + P K + S + ++ ++
Sbjct: 6326 PH---LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESI 6382
Query: 149 TLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIV 208
L C+ SGS P +++W + D ELH E + N + +T +D +
Sbjct: 6383 QLECKISGS-PEIKVSWFRNDSELH-ESWKY----NMSFINSVALLTINEASAEDSGDYI 6436
Query: 209 CSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWE 268
C ++ D S S + V P +P P +G ++L CE G P P + +W
Sbjct: 6437 CEAHNGV---GDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTP-PFEVVWV 6492
Query: 269 KE----GSVPPLKMTQ---ESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSP 321
K+ + K+T +++L L SD G Y C AT+ +GS ++ +P
Sbjct: 6493 KDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPR 6552
Query: 322 VPSSSSTYHAIIGGIV 337
S +IG V
Sbjct: 6553 FVKKLSDTSTLIGDAV 6568
Score = 58.2 bits (139), Expect = 1e-08
Identities = 71/317 (22%), Positives = 123/317 (38%), Gaps = 37/317 (11%)
Query: 30 DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST 89
D +P + D + GT KC V + W+ + R +R +T
Sbjct: 7215 DLKPVSVDLALGESGT--FKCHVTGTAPIKITWAK---------DNREIRPGGNYKMTLV 7263
Query: 90 PHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKP-IITGYKSS--LREKD 146
+ ++++ V D G+YTC + + S LG+ + P I + S +++ +
Sbjct: 7264 ENTATLTVLKVGKGDAGQYTC--YASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDE 7321
Query: 147 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTR--EDDG 204
C+ GS P ++ W K + T IQE + V S ++ +D
Sbjct: 7322 FTRYECKIGGS-PEIKVLWYKDE-------TEIQESSKFRMSFVDSVAVLEMHNLSVEDS 7373
Query: 205 ASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQ 264
C H + A STS ++V P +P P +G + L CE +G P P
Sbjct: 7374 GDYTCEA-HNAAGSASSSTS--LKVKEPPIFRKKPHPIETLKGADVHLECELQGTP-PFH 7429
Query: 265 YLWEKEG----SVPPLKMTQESALIFPFL---NKSDSGTYGCTATSNMGSYKAYYTLNVN 317
W K+ S K+ E+ L + + +D G Y C AT+++GS ++ +
Sbjct: 7430 VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489
Query: 318 DPSPVPSSSSTYHAIIG 334
P S ++G
Sbjct: 7490 APPRFVKKLSDISTVVG 7506
Score = 56.6 bits (135), Expect = 4e-08
Identities = 62/275 (22%), Positives = 108/275 (39%), Gaps = 32/275 (11%)
Query: 65 PAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLV 124
P + +++ +KR LR ++ + S SI I NV +D GEY C + + V
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCK--AQNEVGSDTCV 5601
Query: 125 TVLGIPQKPIITGYKSSLR--EKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 182
+ + + P +SL + A L G++P + W K +E+ I+E
Sbjct: 5602 CTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIF-VQWLKEKEEV------IRES 5654
Query: 183 PNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD 240
N + V + T Q + + + +C + ++ G R + VL + +
Sbjct: 5655 ENIRITFVENVATLQFAKAEPANAGKYICQIKND---GGMRENMATLMVLEPAVIVEKAG 5711
Query: 241 PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNK--------- 291
P G+ L C+ G P W K+G + +T F F NK
Sbjct: 5712 PMTVTVGETCTLECKVAGTP-ELSVEWYKDGKL----LTSSQKHKFSFYNKISSLRILSV 5766
Query: 292 --SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 324
D+GTY +N+G ++V+D + PS
Sbjct: 5767 ERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPS 5801
Score = 55.8 bits (133), Expect = 7e-08
Identities = 67/299 (22%), Positives = 117/299 (39%), Gaps = 50/299 (16%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 102
G +V L+CQV + ++ W Y G+ + LR T + ++ + V +
Sbjct: 6093 GDSVSLQCQVAGTPEITVSW--------YKGDTK-LRPTPEYRTYFTNNVATLVFNKVNI 6143
Query: 103 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTA-----TLNCQSSGS 157
D GEYTC + TA S TV I ++ + + L++ + TL C+ +GS
Sbjct: 6144 NDSGEYTCKAENS-IGTASSK-TVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS 6201
Query: 158 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHES 215
P +R G +++D N +T V + T ++ + D CS ++
Sbjct: 6202 APIQVCWYRDG--------VLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPL 6253
Query: 216 LKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE----- 270
+ + E +P I+P G+ C G P + W K+
Sbjct: 6254 GTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQ-PMRITWSKDNKEIR 6312
Query: 271 ----------GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
G+ P L++ + + K DSG Y C AT+++G L+V +P
Sbjct: 6313 PGGNYTITCVGNTPHLRILK--------VGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 6363
Score = 52.4 bits (124), Expect = 7e-07
Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 34/292 (11%)
Query: 40 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 99
V G C+++ + QW ++ +Y +K ++R S+ + S+ I
Sbjct: 3467 VALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR--------SSKYISSLEILR 3517
Query: 100 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE--KDTATLNCQSSGS 157
+ D GEYTC + + + P SL A C +G+
Sbjct: 3518 TQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGT 3577
Query: 158 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLK 217
P W+K L P D K S++T Q D C +++
Sbjct: 3578 -PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQ-----DRGVYSCKASNKF-- 3629
Query: 218 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHC---EGRGNPVPQQYLWEKEGS-V 273
GAD ++ I ++ P + +P +K+ L C E R V W K+G +
Sbjct: 3630 GADICQAELI-IIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVT----WSKDGQKL 3684
Query: 274 PPLK------MTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
PP K + + L P DSGTY CTA++ GS T+ V +P
Sbjct: 3685 PPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP 3736
Score = 51.6 bits (122), Expect = 1e-06
Identities = 75/322 (23%), Positives = 130/322 (40%), Gaps = 39/322 (12%)
Query: 31 SQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTP 90
++P + D V+ G V LK S+ Q S P + G K + +T
Sbjct: 4210 TKPGSKD--VLPGSAVCLK--------STFQGSTPLTIRWFKGNKELVSGGSCY-ITKEA 4258
Query: 91 HELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTAT- 149
E S+ + V +D G YTC + + S + P + S L +K AT
Sbjct: 4259 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQ 4318
Query: 150 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRE--DDGASI 207
L C+ +G+ P ++TW D+E I+E + V S+ ++T +D
Sbjct: 4319 LACKVTGTPPI-KITWFANDRE-------IKESSKHRMSFVESTAVLRLTDVGIEDSGEY 4370
Query: 208 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLW 267
+C +E+ G+D +S I V +P P + ++L E G P P + W
Sbjct: 4371 MCEAQNEA--GSDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTP-PFEITW 4426
Query: 268 EKEGSVPPLKMTQE----------SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVN 317
K+ ++ L+ ++ S I F+ +D+G Y C T+ +GS + +
Sbjct: 4427 FKDNTI--LRSGRKYKTFIQDHLVSLQILKFV-AADAGEYQCRVTNEVGSSICSARVTLR 4483
Query: 318 DPSPVPSSSSTYHAIIGGIVAF 339
+P + ++ GG AF
Sbjct: 4484 EPPSFIKKIESTSSLRGGTAAF 4505
Score = 51.6 bits (122), Expect = 1e-06
Identities = 63/311 (20%), Positives = 119/311 (38%), Gaps = 40/311 (12%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 102
G V+L+C++ P + ++ +++ +R+++ +TS + S+ I N+
Sbjct: 6472 GSDVILQCEIS---------GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEA 6522
Query: 103 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR 162
+D GEY C S P + + +S D L G +P +
Sbjct: 6523 SDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPIS- 6581
Query: 163 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQV--TREDDGASIVCSVNHESLKGAD 220
+ W K E+ I+E N + + + T Q+ + +C + +++
Sbjct: 6582 VVWLKDRGEV------IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDA---GM 6632
Query: 221 RSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQ 280
R S + VL + +P+P G L C G P W K+G +++
Sbjct: 6633 RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTP-ELSAKWFKDGR----ELSA 6687
Query: 281 ESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS---SS 326
+S F+NK SD G Y +++G +++V+D PS
Sbjct: 6688 DSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKL 6747
Query: 327 STYHAIIGGIV 337
+AI+G V
Sbjct: 6748 KDVNAILGASV 6758
Score = 50.4 bits (119), Expect = 3e-06
Identities = 69/308 (22%), Positives = 117/308 (37%), Gaps = 49/308 (15%)
Query: 36 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSI 95
SD +V G +++L+ S+ W F + + N + +T +
Sbjct: 5993 SDHSVEPGKSIILESTYTGTLPISVTWKKDG-----FNITTSEKCN----IVTTEKTCIL 6043
Query: 96 SISNVALADEGEYTCSIFTMPVR-TAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 153
I N D G+Y+C I R +LV+ L P +T + D+ +L CQ
Sbjct: 6044 EILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPY--FVTELEPLEAAVGDSVSLQCQ 6101
Query: 154 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVT--FQVTREDDGASIVCSV 211
+G+ P ++W KGD T+++ P +T+ ++ T F +D C
Sbjct: 6102 VAGT-PEITVSWYKGD-------TKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 6153
Query: 212 NHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 270
+ S+ A T RI+ P + R G + L C G+ P Q W ++
Sbjct: 6154 EN-SIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS-APIQVCWYRD 6211
Query: 271 G---------------SVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLN 315
G +V LK+ Q S SG Y C+A++ +G+ + L
Sbjct: 6212 GVLLRDDENLQTSFVDNVATLKILQTDL--------SHSGQYSCSASNPLGTASSSARLT 6263
Query: 316 VNDPSPVP 323
+P P
Sbjct: 6264 AREPKKSP 6271
Score = 50.4 bits (119), Expect = 3e-06
Identities = 74/316 (23%), Positives = 120/316 (37%), Gaps = 32/316 (10%)
Query: 36 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEK-RALRDNRIQLVTSTPHELS 94
SD + V G V L+ ++ E S+ W F +K +R++ ++ + + +
Sbjct: 7499 SDISTVVGKEVQLQTTIEGAEPISVVW---------FKDKGEIVRESDNIWISYSENIAT 7549
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK--DTATLNC 152
+ S V A+ G+YTC I + L + + I S++ DT TL C
Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDA--GMQECFATLSVLEPATIVEKPESIKVTTGDTCTLEC 7607
Query: 153 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
+G+ P W K +EL + N VS V D G V S
Sbjct: 7608 TVAGT-PELSTKWFKDGKELTSDNKYKISFFN----KVSGLKIINVAPSDSG---VYSFE 7659
Query: 213 HESLKGADRSTS--QRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 270
++ G D T+ Q + P+ + + G +++ C+ G+P P W E
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSP-PISVSWFHE 7718
Query: 271 GSVPPLKMTQES-------ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVP 323
G+ ++ AL L +SDSG Y C AT+ GS + L V +P
Sbjct: 7719 GNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 7778
Query: 324 SSSSTYHAIIGGIVAF 339
+ G V F
Sbjct: 7779 QKPDPMDVLTGTNVTF 7794
Score = 49.7 bits (117), Expect = 5e-06
Identities = 68/299 (22%), Positives = 122/299 (40%), Gaps = 34/299 (11%)
Query: 40 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 99
V G + L+CQ+ + + W Y G+ + LR + + ++ +
Sbjct: 7972 VSVGDSASLQCQLAGTPEIGVSW--------YKGDTK-LRPTTTYKMHFRNNVATLVFNQ 8022
Query: 100 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE-KDTATL----NCQS 154
V + D GEY C + S T L + ++ + + LR+ ++T L +C
Sbjct: 8023 VDINDSGEYICKAENSVGEVSAS--TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 214
SGS+P + ++W K G+P +++ PN +T + ++ T + + D + S
Sbjct: 8081 SGSEPIS-VSWYKD-----GKP--LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 8132
Query: 215 SLKGADRSTSQRI--EVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE-- 270
+ G+ S+++ I E P IR P G+ C G P + W K+
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQ-PIKVSWAKDSR 8191
Query: 271 ----GSVPPLKMTQESA-LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 324
G + + SA L ++K DSG Y C A + +G LN+ + PS
Sbjct: 8192 EIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 8250
Score = 48.1 bits (113), Expect = 1e-05
Identities = 64/292 (21%), Positives = 110/292 (37%), Gaps = 30/292 (10%)
Query: 40 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 99
++ G + L C++K +P Q +F + L ++ + E + I++
Sbjct: 3749 MLPGESARLHCKLK---------GSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITD 3799
Query: 100 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKP 159
V + D G Y+C + S V+ P I T + + A L C+ SG+ P
Sbjct: 3800 VKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP 3859
Query: 160 AARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQV--TREDDGASIVCSVNHESLK 217
++W K + +I+ + F+ S V ++ D C V +E K
Sbjct: 3860 -FEISWFK-------DKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 3911
Query: 218 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK-------E 270
+T E PT + + D GQ + L RG+ P W K +
Sbjct: 3912 CGCMATHLLKE---PPTFVKKVDDLIALGGQTVTLQAAVRGSE-PISVTWMKGQEVIRED 3967
Query: 271 GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 322
G + + LI P + S G Y C A + GS + L V +P+ +
Sbjct: 3968 GKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKI 4019
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/295 (23%), Positives = 110/295 (37%), Gaps = 32/295 (10%)
Query: 40 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 99
VV V L+C+V P + + R +R ++ +T ++ I+
Sbjct: 4966 VVKYSDVELECEVT---------GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITK 5016
Query: 100 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKP 159
+D GEY C + + S L P I ++ K +AT +GS P
Sbjct: 5017 CDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPP 5076
Query: 160 AARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS--IVCSVNHESLK 217
+ +TW K DQ L ED N V S T Q+ D+G S C +ES
Sbjct: 5077 IS-ITWLKDDQIL-------DEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNES-- 5126
Query: 218 GADRSTSQRIEVLYTPTAMI-RPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS--VP 274
G +R + ++ P ++ + E + L C G P + W K+G VP
Sbjct: 5127 GVERCYA--FLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTP-ELKVKWLKDGKQIVP 5183
Query: 275 PLKMTQE-----SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 324
+ ++ + K DSG Y ++ GS L V D + PS
Sbjct: 5184 SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPS 5238
Score = 47.4 bits (111), Expect = 2e-05
Identities = 56/252 (22%), Positives = 108/252 (42%), Gaps = 26/252 (10%)
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKP-IITGYKSS--LREKDTATLN 151
+++ +V + G+YTC + T V + S T+L + + P + ++S ++ D++ L
Sbjct: 5387 LNLYSVDASKTGQYTCHV-TNDVGS-DSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLE 5444
Query: 152 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTR--EDDGASIVC 209
C+ +GS P R+ W + + EL D TF + S Q+ +D +C
Sbjct: 5445 CKIAGS-PEIRVVWFRNEHELPAS------DKYRMTF-IDSVAVIQMNNLSTEDSGDFIC 5496
Query: 210 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK 269
+ + S S ++ V P P + ++ L CE G P P + +W K
Sbjct: 5497 EAQNPA---GSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTP-PFEVVWYK 5552
Query: 270 EG----SVPPLKMTQES---ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 322
+ S K+ ++ ++ ++ SD G Y C A + +GS T+ + +P
Sbjct: 5553 DKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRF 5612
Query: 323 PSSSSTYHAIIG 334
S ++ + G
Sbjct: 5613 VSKLNSLTVVAG 5624
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/287 (21%), Positives = 112/287 (39%), Gaps = 31/287 (10%)
Query: 51 QVKDHEDSSLQWS---NPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGE 107
QV + ++L+++ P + ++ + R L ++ ++ + + + L D G+
Sbjct: 4027 QVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQ 4086
Query: 108 YTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD-----TATLNCQSSGSKPAAR 162
YT I + S T + + I + LR D T L+C+ +GS P R
Sbjct: 4087 YTFEISNEV--GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPM-R 4143
Query: 163 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKGAD 220
++W K +E I + V + + ++ R D D + C +
Sbjct: 4144 VSWFKDGKE-------IAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSV---GS 4193
Query: 221 RSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE-------GSV 273
+ +S + V P+ + +P G + L +G+ P W K GS
Sbjct: 4194 KDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGS-TPLTIRWFKGNKELVSGGSC 4252
Query: 274 PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPS 320
K ES+L + SDSGTY C ++ G + L V +P+
Sbjct: 4253 YITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 4299
Score = 45.8 bits (107), Expect = 7e-05
Identities = 57/232 (24%), Positives = 94/232 (40%), Gaps = 20/232 (8%)
Query: 86 VTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK 145
+T+T + I + + D G+Y C I + + S ++ P + +
Sbjct: 7916 ITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVG 7975
Query: 146 DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA 205
D+A+L CQ +G+ P ++W KGD +L T N V++ V QV D G
Sbjct: 7976 DSASLQCQLAGT-PEIGVSWYKGDTKLRPTTTYKMHFRN----NVATLVFNQVDINDSGE 8030
Query: 206 SIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQ 264
I + N S+ ST ++ P + R G ++ C G+ P
Sbjct: 8031 YICKAEN--SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSE-PIS 8087
Query: 265 YLWEKEGSVPPLK---------MTQESALIFPFLNKSDSGTYGCTATSNMGS 307
W K+G PLK + + L ++S +G Y CTAT+ +GS
Sbjct: 8088 VSWYKDGK--PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 8137
Score = 45.1 bits (105), Expect = 1e-04
Identities = 65/290 (22%), Positives = 119/290 (41%), Gaps = 34/290 (11%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELS-ISISNVA 101
G V +C++ E + W + + L+D+ L TS H ++ + I
Sbjct: 7130 GFPVAFECRINGSEPLQVSW---------YKDGVLLKDDA-NLQTSFVHNVATLQILQTD 7179
Query: 102 LADEGEYTCSIFTMPVRTAKSLVTVL----GIPQKPIITGYKSSLREKDTATLNCQSSGS 157
+ G+Y CS + P+ TA S ++ +P + L ++ T C +G+
Sbjct: 7180 QSHIGQYNCSA-SNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGT 7238
Query: 158 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLK 217
P ++TW K ++E I+ N K V ++ T V + G + + ++
Sbjct: 7239 API-KITWAKDNRE-------IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIA 7290
Query: 218 GADRSTSQRIEVLYTPTAMIRPDPPH-PREGQKLLLHCEGRGNPVPQQYLWEK------E 270
G D S S ++ V P + + +P ++ + C+ G+P + LW K E
Sbjct: 7291 GKD-SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSP-EIKVLWYKDETEIQE 7348
Query: 271 GSVPPLKMTQESALI-FPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
S + A++ L+ DSG Y C A + GS + +L V +P
Sbjct: 7349 SSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP 7398
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/297 (21%), Positives = 112/297 (37%), Gaps = 41/297 (13%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 102
G V L+C+++ + W + +KR LR + + S SI I NV
Sbjct: 7413 GADVHLECELQGTPPFHVSW---------YKDKRELRSGKKYKIMSENFLTSIHILNVDA 7463
Query: 103 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSS--GSKPA 160
AD GEY C T V + + V + + P S + + Q++ G++P
Sbjct: 7464 ADIGEYQCKA-TNDV-GSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPI 7521
Query: 161 ARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKG 218
+ + W K E+ ++E N + T Q +R + + C + +++
Sbjct: 7522 S-VVWFKDKGEI------VRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDA--- 7571
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKM 278
+ + VL T + +P+ G L C G P W K+G ++
Sbjct: 7572 GMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTP-ELSTKWFKDGK----EL 7626
Query: 279 TQESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 324
T ++ F NK SDSG Y + +G +L V+D + PS
Sbjct: 7627 TSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPS 7683
Score = 43.5 bits (101), Expect = 3e-04
Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 15/238 (6%)
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 154
+ + +V + GEYTC + + + + + P K + S+ + L
Sbjct: 7832 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTF 7891
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 214
+G+ P + +TW+K +G + N T S+ + + +D C + E
Sbjct: 7892 TGTPPIS-VTWKK-----NGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYI--E 7943
Query: 215 SLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVP 274
+ G D S S +I +L P + + +P G L C+ G P ++ + +
Sbjct: 7944 NASGKD-SCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLR 8002
Query: 275 PL---KM---TQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 326
P KM + L+F ++ +DSG Y C A +++G A L V + PS S
Sbjct: 8003 PTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8060
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 97 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSG 156
I+ L DE EY+C VRTA++ + + ++ + T +++ +T T+
Sbjct: 12432 INKCLLDDEAEYSCE-----VRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV 12486
Query: 157 SKPAARLTWRKGDQEL 172
SKP A + W KGD+E+
Sbjct: 12487 SKPGAEVIWYKGDEEI 12502
Score = 43.1 bits (100), Expect = 4e-04
Identities = 61/291 (20%), Positives = 104/291 (35%), Gaps = 35/291 (12%)
Query: 41 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGE-KRALRDNRIQLVTSTPHELSISISN 99
+ G + L+C V S+QW Q+ + K + DN L IS
Sbjct: 4687 IKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFL----------EISQ 4736
Query: 100 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKP 159
+ D G YTCS S + P + + L G+ P
Sbjct: 4737 LEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAP 4796
Query: 160 AARLTWRKGDQELHGEPTR-IQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
+ W K ++ELH R + +D S+S+ + D + +C ++++
Sbjct: 4797 MT-IKWFKDNKELHSGAARSVWKDDT------STSLELFAAKATDSGTYICQLSNDVGTA 4849
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHP-REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLK 277
++T + V P + +P P R GQ C+ G P + W +G+ +
Sbjct: 4850 TSKAT---LFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTP-KIRVSWYLDGN--EIT 4903
Query: 278 MTQESALIF---------PFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
Q+ + F +SGTY C A ++ G+ L V +P
Sbjct: 4904 AIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEP 4954
Score = 42.7 bits (99), Expect = 6e-04
Identities = 65/317 (20%), Positives = 120/317 (37%), Gaps = 41/317 (12%)
Query: 41 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNV 100
V G + +C V + + W+ + R +R ++ + +++ V
Sbjct: 8165 VVGESADFECHVTGTQPIKVSWAK---------DSREIRSGGKYQISYLENSAHLTVLKV 8215
Query: 101 ALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTAT------LNCQS 154
D G+YTC + + S L I ++ I + L E T L +
Sbjct: 8216 DKGDSGQYTC--YAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRV 8273
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRE--DDGASIVCSVN 212
+GS+P + W K + E IQ N + ++++ QV + +D C V+
Sbjct: 8274 AGSQPIT-VAWYKNNIE-------IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVS 8325
Query: 213 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 272
+++ S+ E P P EG+ + L C +G+ P + W K G
Sbjct: 8326 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE-PIRIQWLKAGR 8384
Query: 273 VPPLKMTQESALIFPF---------LNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVP 323
+K + + F + K+DSG Y C A++ GS + + D V
Sbjct: 8385 --EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV- 8441
Query: 324 SSSSTYHAIIGGIVAFI 340
+ +T A + G + F+
Sbjct: 8442 -APATKKAAVDGRLFFV 8457
Score = 42.0 bits (97), Expect = 0.001
Identities = 68/306 (22%), Positives = 115/306 (37%), Gaps = 54/306 (17%)
Query: 41 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNV 100
V G ++ ++C+V S QW ++ + R + R +S+ ++N+
Sbjct: 5249 VLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHER---------SVSLEVNNL 5299
Query: 101 ALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPA 160
L D YTC + + A S + + P ++ + T G+ P
Sbjct: 5300 ELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGT-PP 5358
Query: 161 ARLTWRKGDQELHGEPTRIQEDPNGKT-----FTVSSSVTFQVTREDDGASIVCSVNHES 215
++ W K D EL P + G T ++V +S T Q T C V ++
Sbjct: 5359 FKIKWFKDDVELVSGP-KCFIGLEGSTSFLNLYSVDASKTGQYT---------CHVTND- 5407
Query: 216 LKGADRSTSQRIEVLYTPTAMIRPDPPH----------PREGQKLLLHCEGRGNPVPQQY 265
G+D T T ++ +PP + G L C+ G+P +
Sbjct: 5408 -VGSDSCT----------TMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVV 5456
Query: 266 LWEKEGSVP---PLKMT-QESALIFPFLNKS--DSGTYGCTATSNMGSYKAYYTLNVNDP 319
+ E +P +MT +S + N S DSG + C A + GS + V +P
Sbjct: 5457 WFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP 5516
Query: 320 SPVPSS 325
PV SS
Sbjct: 5517 -PVFSS 5521
Score = 42.0 bits (97), Expect = 0.001
Identities = 65/319 (20%), Positives = 117/319 (36%), Gaps = 30/319 (9%)
Query: 39 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 98
TVVAG L+ ++ + +QW ++ + R++ +T + ++ +
Sbjct: 5620 TVVAGEPAELQASIEGAQPIFVQWLKEKEEVI--------RESENIRITFVENVATLQFA 5671
Query: 99 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 158
A+ G+Y C I ++ P + ++ +T TL C+ +G+
Sbjct: 5672 KAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGT- 5730
Query: 159 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
P + W K + L T Q+ +SS V R+D G + V + K
Sbjct: 5731 PELSVEWYKDGKLL----TSSQKHKFSFYNKISSLRILSVERQDAG-TYTFQVQNNVGKS 5785
Query: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGN-PVPQQYLWEKEGSVPPLK 277
+ + + P+ R G +L C+ G+ P+ + EK V K
Sbjct: 5786 SCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAK 5845
Query: 278 MTQESA-----LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP----------SPV 322
+ L L+ SD G Y C A + GS + L V +P +
Sbjct: 5846 YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVL 5905
Query: 323 PSSSSTYHAIIGGIVAFIV 341
P + T+ ++I G F V
Sbjct: 5906 PGKNVTFTSVIRGTPPFKV 5924
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/298 (24%), Positives = 116/298 (38%), Gaps = 45/298 (15%)
Query: 40 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 99
V G L+ + ++ + +W Q+ L G K + VT T L I +
Sbjct: 4590 VTQGDPATLQVKFSGTKEITAKWFKDGQE-LTLGSKYKIS------VTDTVSILKII--S 4640
Query: 100 VALADEGEYTCSIFTMPVRTA-KSLVTVLGIPQKPIITGYKSSLREKDTAT-----LNCQ 153
D GEYT + R++ K+ + VL + P T L++ D+ L C
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFT---KKLKKMDSIKGSFIDLECI 4697
Query: 154 SSGSKPAARLTWRKGDQELHG-EPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
+GS P + + W K DQE+ E + N +S Q+ D G + CS
Sbjct: 4698 VAGSHPIS-IQWFKDDQEISASEKYKFSFHDNTAFLEIS-----QLEGTDSG-TYTCSAT 4750
Query: 213 HESLKGADRSTSQRIEVLYTPTAMIRPDP----PHPREGQKLLLHCEGRGNPVPQQYLWE 268
+ K S + V P + +P P+ R K L+ G P W
Sbjct: 4751 N---KAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV-----GGTAPMTIKWF 4802
Query: 269 KE------GSVPPLKMTQESALIFPFLNKS-DSGTYGCTATSNMGSYKAYYTLNVNDP 319
K+ G+ + S + F K+ DSGTY C ++++G+ + TL V +P
Sbjct: 4803 KDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Score = 41.2 bits (95), Expect = 0.002
Identities = 68/283 (24%), Positives = 111/283 (39%), Gaps = 39/283 (13%)
Query: 36 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTS-TPHELS 94
SD V +C+V E + +W G + D+R +L+ T H S
Sbjct: 11847 SDVKVFEKDEAKFECEVS-REPKTFRWLK--------GTQEITGDDRFELIKDGTKH--S 11895
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 154
+ I + A DE +Y +F + + + GI K + + +EK++A +
Sbjct: 11896 MVIKSAAFEDEAKY---MFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVEL 11952
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 214
S R+ W K DQ LH + +D GKT S+TF+ DD + I
Sbjct: 11953 SHDN--IRVKWFKNDQRLHTTRSVSMQD-EGKT----HSITFKDLSIDDTSQI------- 11998
Query: 215 SLKGADRSTSQRIEVLY-TPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG-S 272
++ S+ ++ VL P + E +++L CE P + W K+G
Sbjct: 11999 RVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVK--WFKDGKE 12056
Query: 273 VPPLKMT------QESALIFPFLNKSDSGTYGCTATSNMGSYK 309
+ P K ++ LI KSD G Y C ++ S K
Sbjct: 12057 IKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGK 12099
Score = 38.5 bits (88), Expect = 0.011
Identities = 43/236 (18%), Positives = 90/236 (38%), Gaps = 15/236 (6%)
Query: 95 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 154
+ + N+ ++ GEYTC + + + + + P + S+ + L
Sbjct: 5950 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 6009
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 214
+G+ P + +TW+K G E N T + + + + D C + +E
Sbjct: 6010 TGTLPIS-VTWKKD-----GFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENE 6063
Query: 215 SLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVP 274
+ + + +E Y T + +P G + L C+ G P ++ + +
Sbjct: 6064 AGRDVCGALVSTLEPPYFVTEL---EPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 6120
Query: 275 PLK------MTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 324
P + L+F +N +DSG Y C A +++G+ + + + PS
Sbjct: 6121 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPS 6176
Score = 38.5 bits (88), Expect = 0.011
Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 11/88 (12%)
Query: 245 REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT---------QESALIFPFLNKSDSG 295
+ G + L RG P P+ W K+ L + S +SD G
Sbjct: 18214 KAGDTIRLEAGVRGKPFPE-VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272
Query: 296 TYGCTATSNMGSYKAYYTLNVND-PSPV 322
Y TAT+ GS+ AY T+NV D P PV
Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPV 18300
Score = 37.7 bits (86), Expect = 0.018
Identities = 57/291 (19%), Positives = 110/291 (37%), Gaps = 37/291 (12%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 102
GGT + +K ++ W + + R +N + S+ +S + +
Sbjct: 4500 GGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVA---------SLYLSGIEV 4550
Query: 103 ADEGEYTCSIFT-MPVRTAKSLVTVLGIPQKPIITGYKSSL--REKDTATLNCQSSGSKP 159
+G+Y C ++ +L L + + IT S+ + D ATL + SG+K
Sbjct: 4551 KHDGKYVCQAKNDAGIQRCSAL---LSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKE 4607
Query: 160 AARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGA 219
++ G + G +I T TVS ++D G V ++ + +
Sbjct: 4608 ITAKWFKDGQELTLGSKYKISV-----TDTVSILKIISTEKKDSG-EYTFEVQNDVGRSS 4661
Query: 220 DRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT 279
++ ++++ P+ + +G + L C G+ P W K+ +++
Sbjct: 4662 CKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSH-PISIQWFKDDQ----EIS 4716
Query: 280 QESALIFPF-----------LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
F F L +DSGTY C+AT+ G + L V +P
Sbjct: 4717 ASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP 4767
Score = 37.0 bits (84), Expect = 0.031
Identities = 65/303 (21%), Positives = 112/303 (36%), Gaps = 51/303 (16%)
Query: 39 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 98
TV G L+C V + S +W F + R L + +T S+ I
Sbjct: 6655 TVTTGNPFALECVVTGTPELSAKW---------FKDGRELSADSKHHITFINKVASLKIP 6705
Query: 99 NVALADEGEYTCSIFTMPVRTAKSLVTV-LGIPQKPIITGYKSSLREKD-----TATLNC 152
++D+G Y+ F + KS TV + + + + + L++ + + L C
Sbjct: 6706 CAEMSDKGLYS---FEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLEC 6762
Query: 153 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 212
+ SGS P + ++ G++ + G + N T +S + D G + N
Sbjct: 6763 RVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSL-----LEPSDTGIYTCVAAN 6817
Query: 213 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK--- 269
+ G+D ++ + V P+ PD G L RG P P + W K
Sbjct: 6818 ---VAGSDECSAV-LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTP-PFKVKWFKGSR 6872
Query: 270 ------------EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVN 317
E V L++ + L +SG Y C T++ GS L V
Sbjct: 6873 ELVPGESCNISLEDFVTELELFEVQPL--------ESGDYSCLVTNDAGSASCTTHLFVK 6924
Query: 318 DPS 320
+P+
Sbjct: 6925 EPA 6927
Score = 36.2 bits (82), Expect = 0.053
Identities = 67/326 (20%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 36 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSI 95
SD + + G V L+ V+ + S+ W + + R + RI + + ++
Sbjct: 6558 SDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVI-----RESENTRISFIDNIA---TL 6609
Query: 96 SISNVALADEGEYTCSIFT-MPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 154
+ + ++ G+Y C I +R +++TVL P + I ++ + L C
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-PARIIEKPEPMTVTTGNPFALECVV 6668
Query: 155 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 214
+G+ P W K +EL + + TF ++ + ++ + + S +
Sbjct: 6669 TGT-PELSAKWFKDGRELSAD------SKHHITF-INKVASLKIPCAEMSDKGLYSFEVK 6720
Query: 215 SLKGADRST-SQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG- 271
+ G T S + P + IR + G ++L C G+ P W ++G
Sbjct: 6721 NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS-APISVGWFQDGN 6779
Query: 272 ---SVPPLKMTQES---ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP------ 319
S P + + L L SD+G Y C A + GS + L V +P
Sbjct: 6780 EIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT 6839
Query: 320 ----SPVPSSSSTYHAIIGGIVAFIV 341
+P S T+ ++I G F V
Sbjct: 6840 PDSVEVLPGMSLTFTSVIRGTPPFKV 6865
Score = 36.2 bits (82), Expect = 0.053
Identities = 55/219 (25%), Positives = 89/219 (40%), Gaps = 40/219 (18%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHEL-SI 95
D T+ G T + CQ +S P ++ +F R L+ + T H++ +
Sbjct: 8753 DVTLKEGQTCTMTCQ----------FSVPNVKSEWFRNGRILKPQG-RHKTEVEHKVHKL 8801
Query: 96 SISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSS---LREKDTATLNC 152
+I++V D+G+YTC + L I +PI + + E +AT C
Sbjct: 8802 TIADVRAEDQGQYTCKYEDLETSAE------LRIEAEPIQFTKRIQNIVVSEHQSATFEC 8855
Query: 153 QSSGSKPAARLTWRKGDQEL-HGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSV 211
+ S A +TW KG EL + + D T+ + VT +D+G V +
Sbjct: 8856 EVSFDD--AIVTWYKGPTELTESQKYNFRNDGRCHYMTIHN-----VTPDDEGVYSV--I 8906
Query: 212 NHESLKGADRSTSQRIEVLYTPTAMIR-----PDPPHPR 245
+G RST++ LY T I+ PD P R
Sbjct: 8907 ARLEPRGEARSTAE----LYLTTKEIKLELKPPDIPDSR 8941
Score = 35.8 bits (81), Expect = 0.070
Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 220 DRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT 279
++ST+++I+ + +P EG+ C+ G PVP W ++G V
Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP-TVTWLRKGQVLSTSAR 32606
Query: 280 QE-------SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNV 316
+ S + SD G Y ++ G +A +TL +
Sbjct: 32607 HQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Score = 35.0 bits (79), Expect = 0.12
Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 16/128 (12%)
Query: 215 SLKGADRSTSQRIEV--LYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 272
++K DR T+ +++ + T ++R G + L +G P P +W K S
Sbjct: 28345 TIKAVDRLTAPELDIDANFKQTHVVRA-------GASIRLFIAYQGRPTPTA-VWSKPDS 28396
Query: 273 VPPLKMTQESALIFPFL-----NKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327
L+ + F L N++D+G Y T +N GS +T+ V D +P P
Sbjct: 28397 NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLD-TPGPPGPI 28455
Query: 328 TYHAIIGG 335
T+ + G
Sbjct: 28456 TFKDVTRG 28463
Score = 34.3 bits (77), Expect = 0.20
Identities = 34/141 (24%), Positives = 56/141 (39%), Gaps = 25/141 (17%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSIS 96
D+TV G T VL+C+V E++ ++W + L + + D R++ +
Sbjct: 12293 DQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR---------KLV 12342
Query: 97 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSL-----REKDTATLN 151
I + D YTC AK T + P + L REK+ A
Sbjct: 12343 IHDCTPEDIKTYTCD--------AKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFE 12394
Query: 152 CQSSGSKPAARLTWRKGDQEL 172
C+ S+ A++ W K E+
Sbjct: 12395 CEL--SRENAKVKWFKDGAEI 12413
Score = 33.9 bits (76), Expect = 0.27
Identities = 53/229 (23%), Positives = 89/229 (38%), Gaps = 30/229 (13%)
Query: 118 RTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPT 177
RTA TV I GY++S+ ATL + S + A ++T + T
Sbjct: 810 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSET 869
Query: 178 RIQEDPN--------GKTFTVSSSVTFQVTREDDGASI----VCSVNHESLKGADRSTSQ 225
R++ +P T S +V +E G SI V E L G + ++
Sbjct: 870 RVRAEPTPLPQFPFADTPDTYKSEAGVEVKKE-VGVSITGTTVREERFEVLHGREAKVTE 928
Query: 226 R------IEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG----SVP 274
+E+ TP ++ EG+ + L C G P P W +E S
Sbjct: 929 TARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSP-TVTWYREDYQIESSI 987
Query: 275 PLKMTQESALIFPFLNKS---DSGTYGCTATSNMG--SYKAYYTLNVND 318
++T +S + + ++ DSG + C+A + G S Y + V++
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 33.9 bits (76), Expect = 0.27
Identities = 52/270 (19%), Positives = 106/270 (39%), Gaps = 27/270 (10%)
Query: 65 PAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLV 124
P + +F R ++++ ++ + +++V + D GEY C S +
Sbjct: 4327 PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 4386
Query: 125 TVLGIPQKPIITG-YK--SSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE 181
+ + + P T +K L+E D L + +G+ P +TW K + T ++
Sbjct: 4387 VI--VKESPYFTKEFKPIEVLKEYDVMLL-AEVAGTPPF-EITWFKDN-------TILRS 4435
Query: 182 DPNGKTFTVSSSVTFQVTR--EDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP 239
KTF V+ Q+ + D C V +E S R+ + P+ + +
Sbjct: 4436 GRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEV---GSSICSARVTLREPPSFIKKI 4492
Query: 240 DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFLNKSD-- 293
+ G +G+ +P W K+ ++MT E+ + +L+ +
Sbjct: 4493 ESTSSLRGGTAAFQATLKGS-LPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVK 4551
Query: 294 -SGTYGCTATSNMGSYKAYYTLNVNDPSPV 322
G Y C A ++ G + L+V +P+ +
Sbjct: 4552 HDGKYVCQAKNDAGIQRCSALLSVKEPATI 4581
Score = 33.5 bits (75), Expect = 0.35
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 22/152 (14%)
Query: 196 FQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLY------TPTAMIRP---DPPHPRE 246
F VT +G + ++ GA + S+ E + PT ++ P D +
Sbjct: 20333 FTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKA 20392
Query: 247 GQKLLLHCEG-RGNPVPQQYLWEKEGS-VPPLKMTQ------ESALIFPFLNKSDSGTYG 298
G ++L+ G P+P+ W K G + P +TQ S L + + D+G Y
Sbjct: 20393 GDTIVLNAISILGKPLPKSS-WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 20451
Query: 299 CTATSNMGSYKAYYTLNVND----PSPVPSSS 326
TAT+ G+ + + V D P PV S+
Sbjct: 20452 ITATNPFGTKVEHVKVTVLDVPGPPGPVEISN 20483
Score = 33.5 bits (75), Expect = 0.35
Identities = 56/253 (22%), Positives = 91/253 (35%), Gaps = 62/253 (24%)
Query: 114 TMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR-LTWRKGDQEL 172
T P T K V L + P IT + + K+ A L C S A+ +TW K ++L
Sbjct: 32701 TKPTPTEK--VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 32758
Query: 173 HGEPTRIQEDPNGK-TFTVSSSVTFQVT----REDDGASIVCSVN--------------- 212
NG F S+ T+++ E D VC ++
Sbjct: 32759 K---------ENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQ 32809
Query: 213 -----HESL-KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLH------------- 253
HE + K ++ S + T T P P P + +++
Sbjct: 32810 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVA 32869
Query: 254 ---CEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFLNK---SDSGTYGCTATS 303
+ G P P +W K+G K++++ F ++K SDSG Y CT +
Sbjct: 32870 KFAVKATGEPRPTA-IWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 32928
Query: 304 NMGSYKAYYTLNV 316
+ GS + L +
Sbjct: 32929 SAGSVSSSCKLTI 32941
Score = 33.1 bits (74), Expect = 0.45
Identities = 33/114 (28%), Positives = 45/114 (39%), Gaps = 13/114 (11%)
Query: 39 TVVAGGTVVLKC-QVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISI 97
T+ AG T+VL + WS + +R + I +TSTP ++I
Sbjct: 20389 TIKAGDTIVLNAISILGKPLPKSSWSKAGKD---------IRPSDITQITSTPTSSMLTI 20439
Query: 98 SNVALADEGEYTCSIFTMPVRTAKS--LVTVLGIPQKPIITGYKSSLREKDTAT 149
D GEYT + T P T VTVL +P P + EK T T
Sbjct: 20440 KYATRKDAGEYTITA-TNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLT 20492
Score = 32.7 bits (73), Expect = 0.59
Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 25/145 (17%)
Query: 39 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 98
TV G V L C V+ E +QW R ++ + + + +
Sbjct: 8356 TVSEGEYVQLSCHVQGSEPIRIQWLKAG---------REIKPSDRCSFSFASGTAVLELR 8406
Query: 99 NVALADEGEYTCSIFTMP-VRTAKSLVTVLGIP------QKPIITG------YKSSLR-- 143
+VA AD G+Y C + T KS VT+ P +K + G S+R
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVV 8466
Query: 144 EKDTATLNCQSSGSKPAARLTWRKG 168
EK TAT + G P + W KG
Sbjct: 8467 EKTTATFIAKVGGD-PIPNVKWTKG 8490
Score = 32.7 bits (73), Expect = 0.59
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query: 245 REGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFL---NKSDSGTY 297
+ G + L G P+P W+K+G++ +KM + L L N+ DSG Y
Sbjct: 19308 KAGTNVCLDATVFGKPMPT-VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 298 GCTATSNMGSYKAYYTLNVNDPSPVPSS 325
TA ++ GS A L V D P+S
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPAS 19394
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/142 (23%), Positives = 57/142 (40%), Gaps = 25/142 (17%)
Query: 141 SLREKDTATLNCQSSGSKPAARLTWRKGDQELH-GEPTRIQEDPNGKTFTVSSSVTFQVT 199
+++ DT LN S KP + +W K +++ + T+I P T+ T
Sbjct: 20389 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIK-----YAT 20443
Query: 200 REDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPRE-----GQKLLL-- 252
R+D G + + N K + ++V T + P PP P E +K L
Sbjct: 20444 RKDAGEYTITATNPFGTK------VEHVKV----TVLDVPGPPGPVEISNVSAEKATLTW 20493
Query: 253 --HCEGRGNPVPQQYLWEKEGS 272
E G+P+ L ++E S
Sbjct: 20494 TPPLEDGGSPIKSYILEKRETS 20515
Score = 31.6 bits (70), Expect = 1.3
Identities = 43/184 (23%), Positives = 66/184 (35%), Gaps = 17/184 (9%)
Query: 141 SLREKDTATLNCQSSGSKPAARLTWRKGDQEL-HGEPTRIQEDPNGKTFTVSSSVTFQVT 199
S+ E L +G A + W EL + E R + +T T+ Q +
Sbjct: 33049 SINEGQRLVLKANIAG---ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK-----QAS 33100
Query: 200 REDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGN 259
D+G S E + + E+ P + +P + EGQ +L CE G
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 33160
Query: 260 PVPQQYLWEK-------EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYY 312
P P + W K +V + +L + SDSG Y A + G A
Sbjct: 33161 PSP-EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 33219
Query: 313 TLNV 316
+L V
Sbjct: 33220 SLMV 33223
Score = 31.6 bits (70), Expect = 1.3
Identities = 61/311 (19%), Positives = 110/311 (35%), Gaps = 53/311 (17%)
Query: 31 SQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTP 90
SQP + + G V+ C++ ++W F + + ++ +
Sbjct: 33138 SQP--RSQNINEGQNVLFTCEISGEPSPEIEW---------FKNNLPISISSNVSISRSR 33186
Query: 91 HELSISISNVALADEGEY-------------TCSIFTMPVRTAKSLVTVLGIPQKPIITG 137
+ S+ I N +++D G+Y T S+ +P+ S VL + G
Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246
Query: 138 YKSSLREKDTAT---LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSV 194
SS + +A+ + S S A+ +T K + +QE +F SS
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQE-----SFVEMSSS 33301
Query: 195 TFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHC 254
+F + + S + LK R +IE L P EG+ L + C
Sbjct: 33302 SFMGI---SNMTQLESSTSKMLKAGIRGIPPKIEAL--------PSDISIDEGKVLTVAC 33350
Query: 255 EGRGNPVPQQYLW---------EKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNM 305
G P P + W +++G + LI + K D G Y + +
Sbjct: 33351 AFTGEPTP-EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEF 33409
Query: 306 GSYKAYYTLNV 316
GS A +++
Sbjct: 33410 GSDSATVNIHI 33420
Score = 31.2 bits (69), Expect = 1.7
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQ-LVTSTPHELSI 95
D V+ G VL+C+V + +S++W Y +++ D+R+Q +V T L I
Sbjct: 2453 DVNVIEGTKAVLECKVSVPDVTSVKW--------YLNDEQIKPDDRVQAIVKGTKQRLVI 2504
Query: 96 SISNVALADEGEY 108
+ ++ +DEG Y
Sbjct: 2505 NRTHA--SDEGPY 2515
Score = 30.8 bits (68), Expect = 2.2
Identities = 54/296 (18%), Positives = 106/296 (35%), Gaps = 44/296 (14%)
Query: 43 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 102
G + +CQ+ + W L E A++ + I + + IS +
Sbjct: 4876 GQSTTFECQITGTPKIRVSWY------LDGNEITAIQKHGISFIDGLA---TFQISGARV 4926
Query: 103 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR 162
+ G Y C + S+ + P I + + L C+ +G+ P
Sbjct: 4927 ENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPF-E 4985
Query: 163 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVT---FQVTRED--DGASIVCSVNHESLK 217
+TW K ++E+ + K +T++ V+ +T+ D D C V++E
Sbjct: 4986 VTWLKNNREIR----------SSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE--- 5032
Query: 218 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLK 277
G S S R+ + P+ + + + G+P P W K+ +
Sbjct: 5033 GGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSP-PISITWLKDDQI---- 5087
Query: 278 MTQESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 322
+ ++ + F++ SG Y C A + G + Y L V +P+ +
Sbjct: 5088 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI 5143
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 245 REGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQE-SALIFPFLNKSDSGTYGC 299
R L L +G P P+ WEK + +++T + L+ + + DSG Y
Sbjct: 25120 RASATLRLFVTIKGRPEPE-VKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 25178
Query: 300 TATSNMGSYKAYYTLNVNDPSPVP 323
T +N GS A+ + V D P
Sbjct: 25179 TLENNSGSKTAFVNVRVLDSPSAP 25202
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 247 GQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT-----QESALIFPFLNKSDSGTYGCTA 301
G+ L + G PVP + ++EG + ++ +S LI + D G Y TA
Sbjct: 15119 GKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITA 15178
Query: 302 TSNMGSYKAYYTLNVND-PSPV 322
T++ GS A + V D P PV
Sbjct: 15179 TNSCGSKFAAARVEVFDVPGPV 15200
Score = 30.0 bits (66), Expect = 3.8
Identities = 58/240 (24%), Positives = 90/240 (37%), Gaps = 37/240 (15%)
Query: 94 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQ 153
S++I NV D +YT + TA V I + I K + EK A C+
Sbjct: 3024 SLNIRNVHFGDAADYTF-VAGKATSTATLYVEARHIEFRKHIKDIK--VLEKKRAMFECE 3080
Query: 154 SSGSKPAARLTWRKGDQELH-GEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA--SIVCS 210
S +P + W K DQEL + +IQ++ + S TR D ++V
Sbjct: 3081 VS--EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS------TRMSDAGKYTVVAG 3132
Query: 211 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 270
N + K RI + +I E Q+ ++ E + V W K+
Sbjct: 3133 GNVSTAKLFVEGRDVRIRSIKKEVQVI--------EKQRAVVEFEVNEDDVDAH--WYKD 3182
Query: 271 GSVPPLKMTQESALIFP------FLN---KSDSGTYGCTATSNMGSYKAYYTLNVNDPSP 321
G ++ + + F++ +SD+G Y A N S TL VN P P
Sbjct: 3183 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS----VTLYVNAPEP 3238
Score = 29.6 bits (65), Expect = 5.0
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 37 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSIS 96
D+T V + LKC+V +D ++W ++ + K +++ + ++ + +
Sbjct: 11671 DKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVP-SPKYSIKADGLRRI--------LK 11719
Query: 97 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSG 156
I L D+GEY C T + ++ L +KP+ Y + +TA +
Sbjct: 11720 IKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL---YGVEVFVGETAHFEIEL-- 11774
Query: 157 SKPAARLTWRKGDQELHGEP 176
S+P W+ Q L P
Sbjct: 11775 SEPDVHGQWKLKGQPLTASP 11794
Score = 29.3 bits (64), Expect = 6.5
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 15/99 (15%)
Query: 237 IRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV-----PPLKMTQESA-------- 283
+R D + G+ + + + G P+P+ W K +V L++T+E
Sbjct: 15403 VRGDTIKVKAGEPVHIPADVTGLPMPK-IEWSKNETVIEKPTDALQITKEEVSRSEAKTE 15461
Query: 284 LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVND-PSP 321
L P + D GTY TA++ +GS + V D PSP
Sbjct: 15462 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSP 15500
Score = 29.3 bits (64), Expect = 6.5
Identities = 15/44 (34%), Positives = 22/44 (50%)
Query: 273 VPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNV 316
V L + L+ P +SD+G Y TA +N+G+ LNV
Sbjct: 16170 VNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 28.9 bits (63), Expect = 8.5
Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 12/104 (11%)
Query: 245 REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQ----ESALIFPFLN-----KSDSG 295
+ G + + G P P W+K + LK TQ E+ LN +SDSG
Sbjct: 21078 KAGDNIKVEIPVLGRPKPT-VTWKKGDQI--LKQTQRVNFETTATSTILNINECVRSDSG 21134
Query: 296 TYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAF 339
Y TA + +G T+ V+D P+ + + V F
Sbjct: 21135 PYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 21178
>gi|18426911 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 72.4 bits (176), Expect = 7e-13
Identities = 71/281 (25%), Positives = 113/281 (40%), Gaps = 16/281 (5%)
Query: 8 LLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHED-SSLQW---S 63
LL LLL +C W+ QP S V AG T L+C +QW +
Sbjct: 14 LLCLLLAASCAWSGVAGEEELQVIQPDKS-VLVAAGETATLRCTATSLIPVGPIQWFRGA 72
Query: 64 NPAQQTLYFGEKRAL-RDNRIQLVTSTPH-ELSISISNVALADEGEYTCSIFTM----PV 117
P ++ +Y ++ R + +T + + SI I N+ AD G Y C F V
Sbjct: 73 GPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDV 132
Query: 118 RTAKSLVTVLGI---PQKPIITGYKSSLREKDTATLNCQSSGSKPA-ARLTWRKGDQELH 173
T L + P P+++G + + T + C+S G P L W K EL
Sbjct: 133 EFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELS 192
Query: 174 GEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGAD-RSTSQRIEVLYT 232
T + ++++ S+ +TRED + ++C V H +L+G R T+ E +
Sbjct: 193 DFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRV 252
Query: 233 PTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 273
P + P E Q + + P Q W + G+V
Sbjct: 253 PPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNV 293
Score = 29.6 bits (65), Expect = 5.0
Identities = 21/113 (18%), Positives = 42/113 (37%), Gaps = 3/113 (2%)
Query: 116 PVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAA-RLTWRKGDQELHG 174
P+R +L + +P P + + +R ++ + CQ P +LTW +
Sbjct: 239 PLRGTANLSETIRVP--PTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRT 296
Query: 175 EPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRI 227
E + T+ S + V+ D + C V H+ +S ++
Sbjct: 297 ETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKV 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,923,828
Number of Sequences: 37866
Number of extensions: 828677
Number of successful extensions: 4742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 295
Number of HSP's that attempted gapping in prelim test: 2812
Number of HSP's gapped (non-prelim): 1503
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.