Guide to the Human Genome
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Search of human proteins with 10518506

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
         (216 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...   446   e-126
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...   429   e-121
gi|105990535 coagulation factor V precursor [Homo sapiens]            198   3e-51
gi|31317224 EGF-like repeats and discoidin I-like domains-contai...   183   8e-47
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...   167   8e-42
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]           128   4e-30
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]           128   4e-30
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]           128   4e-30
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]           128   4e-30
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]           128   4e-30
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]           128   4e-30
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...   120   9e-28
gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho...   117   6e-27
gi|66864913 neuropilin 1 isoform c [Homo sapiens]                     113   1e-25
gi|66912178 neuropilin 1 isoform b [Homo sapiens]                     113   1e-25
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                    113   1e-25
gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo sa...   110   9e-25
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...   102   2e-22
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...   101   4e-22
gi|10835083 X-linked juvenile retinoschisis protein precursor [H...    96   2e-20
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...    84   9e-17
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]       82   3e-16
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...    80   1e-15
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...    80   1e-15
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...    77   9e-15
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...    77   9e-15
gi|239743729 PREDICTED: similar to contactin associated protein-...    77   9e-15
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]            77   9e-15
gi|38327632 discoidin domain receptor family, member 1 isoform b...    74   1e-13
gi|83977452 discoidin domain receptor family, member 1 isoform c...    74   1e-13

>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score =  446 bits (1147), Expect = e-126
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MRIQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSM 60
           MRIQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSM
Sbjct: 1   MRIQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSM 60

Query: 61  PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQK 120
           PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQK
Sbjct: 61  PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQK 120

Query: 121 TMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNS 180
           TMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNS
Sbjct: 121 TMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNS 180

Query: 181 LDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY 216
           LDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY
Sbjct: 181 LDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY 216


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score =  429 bits (1104), Expect = e-121
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 9    VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKA 68
            VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKA
Sbjct: 2144 VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKA 2203

Query: 69   ISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVT 128
            ISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVT
Sbjct: 2204 ISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVT 2263

Query: 129  TQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTR 188
            TQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTR
Sbjct: 2264 TQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTR 2323

Query: 189  YLRIHPQSWVHQIALRMEVLGCEAQDLY 216
            YLRIHPQSWVHQIALRMEVLGCEAQDLY
Sbjct: 2324 YLRIHPQSWVHQIALRMEVLGCEAQDLY 2351



 Score =  121 bits (304), Expect = 4e-28
 Identities = 63/158 (39%), Positives = 88/158 (55%), Gaps = 8/158 (5%)

Query: 56   NSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQ 115
            N C  PLGM S  I D QITAS      +  W+P  ARLH  G  NAW      P  W++
Sbjct: 2038 NKCQTPLGMASGHIRDFQITASG----QYGQWAPKLARLHYSGSINAW--STKEPFSWIK 2091

Query: 116  VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQN--GKVKVFQGNQDS 173
            VD    M + G+ TQG +   +S+Y+ +F+I  S DG +W  +  N  G + VF GN DS
Sbjct: 2092 VDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDS 2151

Query: 174  FTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
                 N  +PP++ RY+R+HP  +  +  LRME++GC+
Sbjct: 2152 SGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCD 2189



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 21/47 (44%), Positives = 31/47 (65%)

Query: 8    KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCD 54
            KVF GN DS     N  +PP++ RY+R+HP  +  +  LRME++GC+
Sbjct: 2300 KVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 2346


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score =  198 bits (503), Expect = 3e-51
 Identities = 95/205 (46%), Positives = 138/205 (67%), Gaps = 3/205 (1%)

Query: 10   FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAI 69
            F GN D+S IK N F+PPI+ARYIR+ PT    R TLR+EL GC++N CS PLGME+  I
Sbjct: 2018 FNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKI 2077

Query: 70   SDAQITASSYFTNMFAT-WSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVT 128
             + QITASS+  + +   W P +ARL+ QGR NAW+ + NN K+WL++D  K  K+T + 
Sbjct: 2078 ENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAII 2137

Query: 129  TQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV--KVFQGNQDSFTPVVNSLDPPLL 186
            TQG KSL + MYVK + I  S+ G +W  +     +  K+F+GN ++   V N  +PP++
Sbjct: 2138 TQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPII 2197

Query: 187  TRYLRIHPQSWVHQIALRMEVLGCE 211
            +R++R+ P++W   IALR+E+ GC+
Sbjct: 2198 SRFIRVIPKTWNQSIALRLELFGCD 2222



 Score =  113 bits (282), Expect = 1e-25
 Identities = 63/160 (39%), Positives = 86/160 (53%), Gaps = 10/160 (6%)

Query: 58   CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNP----KEW 113
            C MP+G+ +  ISD+QI AS +       W P  ARL+  G  NAW  +        K W
Sbjct: 1907 CRMPMGLSTGIISDSQIKASEFL----GYWEPRLARLNNGGSYNAWSVEKLAAEFASKPW 1962

Query: 114  LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNG--KVKVFQGNQ 171
            +QVD QK + +TG+ TQG K  L S Y  EF ++ S +   W +F  N    V  F GN 
Sbjct: 1963 IQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNS 2022

Query: 172  DSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
            D+ T   N  DPP++ RY+RI P    ++  LR+E+ GCE
Sbjct: 2023 DASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCE 2062



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 23/48 (47%), Positives = 33/48 (68%)

Query: 8    KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 55
            K+F GN ++ G   N FNPPII+R+IR+ P  ++    LR+EL GCD+
Sbjct: 2176 KIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDI 2223


>gi|31317224 EGF-like repeats and discoidin I-like
           domains-containing protein 3 [Homo sapiens]
          Length = 480

 Score =  183 bits (465), Expect = 8e-47
 Identities = 98/211 (46%), Positives = 129/211 (61%), Gaps = 5/211 (2%)

Query: 9   VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKA 68
           VF GN+D++    N F PPI A+Y+RL+P       TLRMEL+GC+L+ CS PLGM+S  
Sbjct: 270 VFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGH 329

Query: 69  ISDAQITASSYFTNM---FATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVT 125
           I D QITASS F  +     TW P KARL  QG+ NAW    N+  +WLQVD     KVT
Sbjct: 330 IQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVT 389

Query: 126 GVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--FQNGKVKVFQGNQDSFTPVVNSLDP 183
           G+ TQG K      +V  + ++ S DG  WT++   +  K KVFQGN D+ T   N +DP
Sbjct: 390 GIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDP 449

Query: 184 PLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
           P+  R++RI P SW  +I LR E+LGC  ++
Sbjct: 450 PIYARHIRILPWSWYGRITLRSELLGCTEEE 480



 Score =  129 bits (324), Expect = 2e-30
 Identities = 71/168 (42%), Positives = 99/168 (58%), Gaps = 5/168 (2%)

Query: 49  ELMGCDLN-SCSMPLGMESKAISDAQITASSYFTNMFAT--WSPSKARLHLQGRSNAWRP 105
           E MG +    CS PLG+E   IS+ QITASS    +F    W P  ARL+ +G  NAW  
Sbjct: 148 EFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTA 207

Query: 106 QVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNG--K 163
             N+   W+Q++ Q+ M+VTGV TQG K + +  Y+K + I+ S DG  W ++   G  +
Sbjct: 208 AENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNE 267

Query: 164 VKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
             VF+GN D+ TP  NS  PP+  +Y+R++PQ       LRME+LGCE
Sbjct: 268 DMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCE 315



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 24/50 (48%), Positives = 32/50 (64%)

Query: 4   QDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 53
           Q   KVF GN D+   + N+ +PPI AR+IR+ P  +  R TLR EL+GC
Sbjct: 427 QRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 476


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score =  167 bits (422), Expect = 8e-42
 Identities = 84/208 (40%), Positives = 126/208 (60%), Gaps = 5/208 (2%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESK 67
           K F GN + + +  N+F  P+ A+Y+RL+PT      TLR EL+GC+LN C+ PLG+++ 
Sbjct: 180 KEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNN 239

Query: 68  AISDAQITASSYFTNM---FATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKV 124
           +I D QITASS +        +W+PS ARL  QG  NAW        +WLQVD   + +V
Sbjct: 240 SIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEV 299

Query: 125 TGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFF--QNGKVKVFQGNQDSFTPVVNSLD 182
           TG+ TQG ++  +  +V  + ++ S D   WT +   + G  K+F GN D+ +   N  +
Sbjct: 300 TGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFE 359

Query: 183 PPLLTRYLRIHPQSWVHQIALRMEVLGC 210
            P+L RY+RI P +W ++IALR+E+LGC
Sbjct: 360 TPILARYVRILPVAWHNRIALRLELLGC 387



 Score =  106 bits (265), Expect = 1e-23
 Identities = 60/157 (38%), Positives = 85/157 (54%), Gaps = 3/157 (1%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFAT--WSPSKARLHLQGRSNAWRPQVNNPKEWLQ 115
           C  PLG+E+  I+++QI ASS          W P  ARL+  G  NAW P  N+   W+Q
Sbjct: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQ 129

Query: 116 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ-NGKVKVFQGNQDSF 174
           V+  + M VTGV TQG   L +  Y+K F ++ S +GH++      N K K F GN +  
Sbjct: 130 VNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKN 189

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
              VN  + P+  +Y+R++P S      LR E+LGCE
Sbjct: 190 AVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score =  114 bits (285), Expect = 6e-26
 Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 20/221 (9%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV---KVFQGNQDSF 174
           V GV  QG      + ++    +V++F +S S +G  W  + Q+ +    K+F+GN    
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE-YIQDPRTQQPKLFEGNMHYD 556

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQ-IALRMEVLGCEAQD 214
           TP +   D P+  +Y+R++P+ W    I +R+EVLGC+  D
Sbjct: 557 TPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCDWTD 596


>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
          Length = 901

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score =  114 bits (285), Expect = 6e-26
 Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 20/221 (9%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV---KVFQGNQDSF 174
           V GV  QG      + ++    +V++F +S S +G  W  + Q+ +    K+F+GN    
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE-YIQDPRTQQPKLFEGNMHYD 556

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQ-IALRMEVLGCEAQD 214
           TP +   D P+  +Y+R++P+ W    I +R+EVLGC+  D
Sbjct: 557 TPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCDWTD 596


>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
          Length = 931

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score =  114 bits (285), Expect = 6e-26
 Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 20/221 (9%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV---KVFQGNQDSF 174
           V GV  QG      + ++    +V++F +S S +G  W  + Q+ +    K+F+GN    
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE-YIQDPRTQQPKLFEGNMHYD 556

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQ-IALRMEVLGCEAQD 214
           TP +   D P+  +Y+R++P+ W    I +R+EVLGC+  D
Sbjct: 557 TPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCDWTD 596


>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
          Length = 555

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score = 84.0 bits (206), Expect = 9e-17
 Identities = 57/158 (36%), Positives = 83/158 (52%), Gaps = 14/158 (8%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQW 155
           V GV  QG      + ++    +V++F +S S +G  W
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDW 535


>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
          Length = 906

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score =  114 bits (285), Expect = 6e-26
 Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 20/221 (9%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV---KVFQGNQDSF 174
           V GV  QG      + ++    +V++F +S S +G  W  + Q+ +    K+F+GN    
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE-YIQDPRTQQPKLFEGNMHYD 556

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQ-IALRMEVLGCEAQD 214
           TP +   D P+  +Y+R++P+ W    I +R+EVLGC+  D
Sbjct: 557 TPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCDWTD 596


>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
          Length = 926

 Score =  128 bits (321), Expect = 4e-30
 Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C++PLGMES  I++ QI+ASS +++    W+P ++RLH  G  N W P +++ KE+LQVD
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332

Query: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
            +    +T + TQG  S  T    YVK + +  S +G  W ++      KVFQ N D+  
Sbjct: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            V+N L  PLLTR++RI PQ+W   IALR+E+ GC   D
Sbjct: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431



 Score =  114 bits (285), Expect = 6e-26
 Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 20/221 (9%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
           KVF  N D++ +  N  + P++ R++R+ P  +     LR+EL GC +    CS  LGM 
Sbjct: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441

Query: 66  SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
           S  I+D+QI+ASS        WSPS ARL +  RS  +   PQ    +EWLQVD      
Sbjct: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497

Query: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKV---KVFQGNQDSF 174
           V GV  QG      + ++    +V++F +S S +G  W  + Q+ +    K+F+GN    
Sbjct: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE-YIQDPRTQQPKLFEGNMHYD 556

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQ-IALRMEVLGCEAQD 214
           TP +   D P+  +Y+R++P+ W    I +R+EVLGC+  D
Sbjct: 557 TPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCDWTD 596


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score =  120 bits (301), Expect = 9e-28
 Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 9/178 (5%)

Query: 41  SIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYF-----TNMFATWSPSKARLH 95
           S+   L   L     + C   LGMES  I+D QITASS       T    +W P KARL 
Sbjct: 275 SVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK 334

Query: 96  LQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW 155
             G    W     +  +WLQ+D  K  K+TG+ T G   +  + YV  + I  S DG +W
Sbjct: 335 KPGPP--WAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW 392

Query: 156 TLFFQNG--KVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
           T++ + G  + K+FQGN+D    V N+  PP++ R++R++P  W  +IA++ME+LGC+
Sbjct: 393 TVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 24/54 (44%), Positives = 35/54 (64%), Gaps = 4/54 (7%)

Query: 4   QDPG----KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 53
           ++PG    K+F GN D      N F PPIIAR+IR++PT +  +  ++MEL+GC
Sbjct: 396 REPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449


>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
           sapiens]
          Length = 335

 Score =  117 bits (294), Expect = 6e-27
 Identities = 69/206 (33%), Positives = 99/206 (48%), Gaps = 53/206 (25%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESK 67
           K F GN + + +  N+F  P+ A+Y+RL+PT      TLR EL+GC+LN C+ PLG+++ 
Sbjct: 180 KEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNN 239

Query: 68  AISDAQITASSYFTNM---FATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKV 124
           +I D QITASS +        +W+PS ARL  QG  NAW        +WLQ         
Sbjct: 240 SIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQ--------- 290

Query: 125 TGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPP 184
                                                    +F GN D+ +   N  + P
Sbjct: 291 -----------------------------------------IFPGNWDNHSHKKNLFETP 309

Query: 185 LLTRYLRIHPQSWVHQIALRMEVLGC 210
           +L RY+RI P +W ++IALR+E+LGC
Sbjct: 310 ILARYVRILPVAWHNRIALRLELLGC 335



 Score =  106 bits (265), Expect = 1e-23
 Identities = 60/157 (38%), Positives = 85/157 (54%), Gaps = 3/157 (1%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFAT--WSPSKARLHLQGRSNAWRPQVNNPKEWLQ 115
           C  PLG+E+  I+++QI ASS          W P  ARL+  G  NAW P  N+   W+Q
Sbjct: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQ 129

Query: 116 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ-NGKVKVFQGNQDSF 174
           V+  + M VTGV TQG   L +  Y+K F ++ S +GH++      N K K F GN +  
Sbjct: 130 VNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKN 189

Query: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
              VN  + P+  +Y+R++P S      LR E+LGCE
Sbjct: 190 AVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226


>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
          Length = 609

 Score =  113 bits (283), Expect = 1e-25
 Identities = 70/211 (33%), Positives = 111/211 (52%), Gaps = 10/211 (4%)

Query: 9   VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGMES 66
           +F GN + + +   +F  P+I R++R+ P  +    ++R E+ GC +    CS  LGM S
Sbjct: 380 LFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVS 439

Query: 67  KAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNP-KEWLQVDFQKTMKVT 125
             ISD+QIT+S+        W P   RL       A  P  ++   EWLQ+D  +   V 
Sbjct: 440 GLISDSQITSSNQGDR---NWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVR 496

Query: 126 GVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNG--KVKVFQGNQDSFTPVVNSLDP 183
           G+  QG K     +++++F I  S +G  W +   +   K K F+GN +  TP + +  P
Sbjct: 497 GIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-P 555

Query: 184 PLLTRYLRIHPQSWVH-QIALRMEVLGCEAQ 213
            L TR++RI+P+   H  + LRME+LGCE +
Sbjct: 556 ALSTRFIRIYPERATHGGLGLRMELLGCEVE 586



 Score =  103 bits (257), Expect = 1e-22
 Identities = 62/159 (38%), Positives = 83/159 (52%), Gaps = 7/159 (4%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C   LGMES  I   QITASS ++     WS  ++RL+     N W P  ++ +EW+QVD
Sbjct: 275 CMEALGMESGEIHSDQITASSQYST---NWSAERSRLNYP--ENGWTPGEDSYREWIQVD 329

Query: 118 FQKTMKVTGVTTQGVKSLLTSM--YVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
                 VT V TQG  S  T    YVK + I  S +G  W    +  K  +FQGN +   
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            VV     PL+TR++RI P +W   I++R EV GC+  D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITD 428



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 5/52 (9%)

Query: 26  PPIIARYIRLHP---THYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQI 74
           P +  R+IR++P   TH  +   LRMEL+GC++   +  L  E   + D+ I
Sbjct: 555 PALSTRFIRIYPERATHGGLG--LRMELLGCEVEGGTTVLATEKPTVIDSTI 604


>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
          Length = 644

 Score =  113 bits (283), Expect = 1e-25
 Identities = 70/211 (33%), Positives = 111/211 (52%), Gaps = 10/211 (4%)

Query: 9   VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGMES 66
           +F GN + + +   +F  P+I R++R+ P  +    ++R E+ GC +    CS  LGM S
Sbjct: 380 LFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVS 439

Query: 67  KAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNP-KEWLQVDFQKTMKVT 125
             ISD+QIT+S+        W P   RL       A  P  ++   EWLQ+D  +   V 
Sbjct: 440 GLISDSQITSSNQGDR---NWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVR 496

Query: 126 GVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNG--KVKVFQGNQDSFTPVVNSLDP 183
           G+  QG K     +++++F I  S +G  W +   +   K K F+GN +  TP + +  P
Sbjct: 497 GIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-P 555

Query: 184 PLLTRYLRIHPQSWVH-QIALRMEVLGCEAQ 213
            L TR++RI+P+   H  + LRME+LGCE +
Sbjct: 556 ALSTRFIRIYPERATHGGLGLRMELLGCEVE 586



 Score =  103 bits (257), Expect = 1e-22
 Identities = 62/159 (38%), Positives = 83/159 (52%), Gaps = 7/159 (4%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C   LGMES  I   QITASS ++     WS  ++RL+     N W P  ++ +EW+QVD
Sbjct: 275 CMEALGMESGEIHSDQITASSQYST---NWSAERSRLNYP--ENGWTPGEDSYREWIQVD 329

Query: 118 FQKTMKVTGVTTQGVKSLLTSM--YVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
                 VT V TQG  S  T    YVK + I  S +G  W    +  K  +FQGN +   
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            VV     PL+TR++RI P +W   I++R EV GC+  D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITD 428



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 5/35 (14%)

Query: 26  PPIIARYIRLHP---THYSIRSTLRMELMGCDLNS 57
           P +  R+IR++P   TH  +   LRMEL+GC++ +
Sbjct: 555 PALSTRFIRIYPERATHGGLG--LRMELLGCEVEA 587


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score =  113 bits (283), Expect = 1e-25
 Identities = 70/211 (33%), Positives = 111/211 (52%), Gaps = 10/211 (4%)

Query: 9   VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGMES 66
           +F GN + + +   +F  P+I R++R+ P  +    ++R E+ GC +    CS  LGM S
Sbjct: 380 LFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVS 439

Query: 67  KAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNP-KEWLQVDFQKTMKVT 125
             ISD+QIT+S+        W P   RL       A  P  ++   EWLQ+D  +   V 
Sbjct: 440 GLISDSQITSSNQGDR---NWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVR 496

Query: 126 GVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNG--KVKVFQGNQDSFTPVVNSLDP 183
           G+  QG K     +++++F I  S +G  W +   +   K K F+GN +  TP + +  P
Sbjct: 497 GIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTF-P 555

Query: 184 PLLTRYLRIHPQSWVH-QIALRMEVLGCEAQ 213
            L TR++RI+P+   H  + LRME+LGCE +
Sbjct: 556 ALSTRFIRIYPERATHGGLGLRMELLGCEVE 586



 Score =  103 bits (257), Expect = 1e-22
 Identities = 62/159 (38%), Positives = 83/159 (52%), Gaps = 7/159 (4%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C   LGMES  I   QITASS ++     WS  ++RL+     N W P  ++ +EW+QVD
Sbjct: 275 CMEALGMESGEIHSDQITASSQYST---NWSAERSRLNYP--ENGWTPGEDSYREWIQVD 329

Query: 118 FQKTMKVTGVTTQGVKSLLTSM--YVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
                 VT V TQG  S  T    YVK + I  S +G  W    +  K  +FQGN +   
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389

Query: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
            VV     PL+TR++RI P +W   I++R EV GC+  D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITD 428



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 5/35 (14%)

Query: 26  PPIIARYIRLHP---THYSIRSTLRMELMGCDLNS 57
           P +  R+IR++P   TH  +   LRMEL+GC++ +
Sbjct: 555 PALSTRFIRIYPERATHGGLG--LRMELLGCEVEA 587


>gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo
           sapiens]
          Length = 539

 Score =  110 bits (275), Expect = 9e-25
 Identities = 62/165 (37%), Positives = 94/165 (56%), Gaps = 13/165 (7%)

Query: 56  NSCSMPLGMESKAISDAQITASSYFTNMFAT-----WSPSKARLHLQGRSNAWRPQVNN- 109
           N CS  L  E     D QI ASS + ++  +     WSP +ARL  QG S A     NN 
Sbjct: 253 NGCSRSLSFEP----DGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNH 308

Query: 110 -PKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--FQNGKVKV 166
            P+EWL++D  +  K+TG+ T G      + YVK F+++   +  +W  +    N + KV
Sbjct: 309 KPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKV 368

Query: 167 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
           FQGN +   PV N+  PP++ RY+R+ PQ+W  +IAL++E++GC+
Sbjct: 369 FQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQ 413



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 21/53 (39%), Positives = 32/53 (60%)

Query: 3   IQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 55
           + +  KVF GN +      N F PPI+ARY+R+ P  +  R  L++EL+GC +
Sbjct: 362 VNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQI 414


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score =  102 bits (255), Expect = 2e-22
 Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 10/163 (6%)

Query: 61  PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQVNNPKEW 113
           P+GMES  I D QI ASS   +        + RL++Q  +        AW  + +   +W
Sbjct: 387 PIGMESHRIEDNQIRASSMLRHGLGA---QRGRLNMQTGATEDDYYDGAWCAEDDARTQW 443

Query: 114 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDS 173
           ++VD ++T + TGV TQG  S +   +V  F +  S D   W ++    +   F GN D 
Sbjct: 444 IEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDK 503

Query: 174 FTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY 216
            TPV++ L  P++ R++RI+P +W   + +R+EVLGC    +Y
Sbjct: 504 DTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVY 546



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 55
           F GNVD      +    P++AR+IR++P  ++    +R+E++GC +
Sbjct: 497 FHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score =  101 bits (252), Expect = 4e-22
 Identities = 58/170 (34%), Positives = 88/170 (51%), Gaps = 12/170 (7%)

Query: 54  DLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQ 106
           D+     PLG+E+  I+D Q+ AS+            + RL++Q   N       AW   
Sbjct: 131 DVRESCPPLGLETLKITDFQLHASTVKRYGLGA---HRGRLNIQAGINENDFYDGAWCAG 187

Query: 107 VNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKV 166
            N+ ++W++VD ++  + TGV TQG  SL  S +V  + +  S D H W          +
Sbjct: 188 RNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI 247

Query: 167 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVH--QIALRMEVLGCEAQD 214
           F+GN +   PV+N L  P++ RY+RI+PQSW     I +RME+LGC   D
Sbjct: 248 FEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 9   VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDL 55
           +F GN +      N    P++ARYIR++P  +    +  +RME++GC L
Sbjct: 247 IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295


>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
           sapiens]
          Length = 224

 Score = 95.9 bits (237), Expect = 2e-20
 Identities = 50/154 (32%), Positives = 89/154 (57%), Gaps = 6/154 (3%)

Query: 61  PLGMESKAISDAQITASS--YFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDF 118
           PLG ES  ++  QIT S+   +   +++W+ +KARL+ QG   AW  +  +  +WLQ+D 
Sbjct: 68  PLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDL 127

Query: 119 QKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFF--QNGKVKVFQGNQDSFTP 176
           ++   ++G+ TQG   +    ++ ++ +    D     +++  Q G  +VF GN D  + 
Sbjct: 128 KEIKVISGILTQGRCDI--DEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTST 185

Query: 177 VVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGC 210
           V N L PP+++R++R+ P  W  +IA+RME+L C
Sbjct: 186 VQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC 219



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 21/46 (45%), Positives = 31/46 (67%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 53
           +VF+GN D +    N+  PPII+R+IRL P  + +R  +RMEL+ C
Sbjct: 174 RVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC 219


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
           sapiens]
          Length = 1331

 Score = 84.0 bits (206), Expect = 9e-17
 Identities = 49/155 (31%), Positives = 82/155 (52%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL      +S     A S  +++  ++SP  A+++ +G +  W P  ++  +WLQVD
Sbjct: 35  CDEPL------VSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVD 88

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
           F    +++ + TQG  S  +S +V ++ +  S  G  W  + Q+G +  F GN +S   V
Sbjct: 89  FGNRKQISAIATQGRYS--SSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVV 146

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
            + L  P++ RY+RI P  W    +I LR+EV GC
Sbjct: 147 RHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYS--IRSTLRMELMGC 53
           F GN++S G+  +    PIIARY+R+ P  ++   R  LR+E+ GC
Sbjct: 136 FPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181


>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
          Length = 734

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 14/165 (8%)

Query: 61  PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGR-------SNAWRPQVNNPKEW 113
           PLG+ES  +SD+++ ASS  +  F    P + RL++Q           AW  +  +   W
Sbjct: 117 PLGLESLRVSDSRLEASS--SQSFGL-GPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPW 173

Query: 114 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW--TLFFQNGKVKVFQGNQ 171
            QVD     + +GV TQG  S+    +V  + +  S D   W  +    +G   VF  N 
Sbjct: 174 FQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233

Query: 172 DSFTPVVNSLDPPLLTRYLRIHPQSWVHQIA--LRMEVLGCEAQD 214
           D  TPV+N L  P + R++R+ PQ+W+   A  LR E+L C   D
Sbjct: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 6   CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 59

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 60  LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 117

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 118 YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSI--RSTLRMELMGCDLNS 57
           F GN ++  + +    P I AR++R  P  ++   R  +R+E+ GC   S
Sbjct: 107 FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRS 156


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 31  CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 84

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 85  LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 142

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 143 YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSI--RSTLRMELMGCDLNS 57
           F GN ++  + +    P I AR++R  P  ++   R  +R+E+ GC   S
Sbjct: 132 FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRS 181


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 77.4 bits (189), Expect = 9e-15
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 31  CDSPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 85  LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 57
           F GN ++  + H    PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 132 FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
           [Homo sapiens]
          Length = 1288

 Score = 77.4 bits (189), Expect = 9e-15
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 31  CDSPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 85  LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 57
           F GN ++  + H    PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 132 FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score = 77.4 bits (189), Expect = 9e-15
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 31  CDAPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 85  LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 57
           F GN ++  + H    PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 132 FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 77.4 bits (189), Expect = 9e-15
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
           C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 31  CDAPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84

Query: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177
             + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 85  LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142

Query: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210
              L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 32.0 bits (71), Expect = 0.41
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 57
           F GN ++  + H    PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 132 FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181


>gi|38327632 discoidin domain receptor family, member 1 isoform b
           [Homo sapiens]
          Length = 876

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 16/170 (9%)

Query: 54  DLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN----AWRPQVN- 108
           D   C   LGM+ + I D+ I+ASS       +WS S A  H +  S+    AW P  + 
Sbjct: 27  DPAKCRYALGMQDRTIPDSDISASS-------SWSDSTAARHSRLESSDGDGAWCPAGSV 79

Query: 109 --NPKEWLQVDFQKTMKVTGVTTQGVKSL-LTSMYVKEFLISSSQDGHQWTLFFQNGKVK 165
               +E+LQVD Q+   V  V TQG  +  L   + + + +  S+DG +W  +      +
Sbjct: 80  FPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQE 139

Query: 166 VFQGNQDSFTPVVNSLDPPLLTRYLRIHPQS-WVHQIALRMEVLGCEAQD 214
           V  GN+D    V+  L PP++ R +R +P++  V  + LR+E+ GC  +D
Sbjct: 140 VISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRD 189



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST-LRMELMGC----DLNSCSMPL 62
           +V  GN D  G+      PP++AR +R +P    + S  LR+EL GC     L S + P+
Sbjct: 139 EVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPV 198

Query: 63  GMESKAISDAQITASSY 79
           G          +  S+Y
Sbjct: 199 GQTMYLSEAVYLNDSTY 215


>gi|83977452 discoidin domain receptor family, member 1 isoform c
           [Homo sapiens]
          Length = 919

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 16/170 (9%)

Query: 54  DLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN----AWRPQVN- 108
           D   C   LGM+ + I D+ I+ASS       +WS S A  H +  S+    AW P  + 
Sbjct: 27  DPAKCRYALGMQDRTIPDSDISASS-------SWSDSTAARHSRLESSDGDGAWCPAGSV 79

Query: 109 --NPKEWLQVDFQKTMKVTGVTTQGVKSL-LTSMYVKEFLISSSQDGHQWTLFFQNGKVK 165
               +E+LQVD Q+   V  V TQG  +  L   + + + +  S+DG +W  +      +
Sbjct: 80  FPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQE 139

Query: 166 VFQGNQDSFTPVVNSLDPPLLTRYLRIHPQS-WVHQIALRMEVLGCEAQD 214
           V  GN+D    V+  L PP++ R +R +P++  V  + LR+E+ GC  +D
Sbjct: 140 VISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRD 189



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST-LRMELMGC----DLNSCSMPL 62
           +V  GN D  G+      PP++AR +R +P    + S  LR+EL GC     L S + P+
Sbjct: 139 EVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPV 198

Query: 63  GMESKAISDAQITASSY 79
           G          +  S+Y
Sbjct: 199 GQTMYLSEAVYLNDSTY 215


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,335,816
Number of Sequences: 37866
Number of extensions: 323415
Number of successful extensions: 804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 615
Number of HSP's gapped (non-prelim): 92
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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