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Search of human proteins with 18640734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18640734 contactin associated protein-like 5 [Homo sapiens]
(1306 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18640734 contactin associated protein-like 5 [Homo sapiens] 2687 0.0
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 1595 0.0
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 1508 0.0
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 1407 0.0
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1... 1399 0.0
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 1338 0.0
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2... 1074 0.0
gi|4505463 contactin associated protein 1 precursor [Homo sapiens] 938 0.0
gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 548 e-155
gi|239743729 PREDICTED: similar to contactin associated protein-... 427 e-119
gi|169184330 PREDICTED: novel protein similar to contactin assoc... 197 4e-50
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 127 5e-29
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 127 9e-29
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 120 1e-26
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 119 2e-26
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 117 7e-26
gi|239758135 PREDICTED: similar to cell recognition molecule CAS... 105 2e-22
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 89 3e-17
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 87 8e-17
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 87 8e-17
gi|33469935 EGF-like, fibronectin type III and laminin G domains... 86 2e-16
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 82 3e-15
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 82 3e-15
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 82 3e-15
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 80 1e-14
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 77 8e-14
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 77 1e-13
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 77 1e-13
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 77 1e-13
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 77 1e-13
>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
Length = 1306
Score = 2687 bits (6966), Expect = 0.0
Identities = 1306/1306 (100%), Positives = 1306/1306 (100%)
Query: 1 MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNW 60
MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNW
Sbjct: 1 MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNW 60
Query: 61 RVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQY 120
RVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQY
Sbjct: 61 RVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQY 120
Query: 121 KQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDV 180
KQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDV
Sbjct: 121 KQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDV 180
Query: 181 ADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLAL 240
ADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLAL
Sbjct: 181 ADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLAL 240
Query: 241 HLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDA 300
HLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDA
Sbjct: 241 HLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDA 300
Query: 301 LDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSC 360
LDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSC
Sbjct: 301 LDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSC 360
Query: 361 SEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSL 420
SEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSL
Sbjct: 361 SEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSL 420
Query: 421 EGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWV 480
EGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWV
Sbjct: 421 EGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWV 480
Query: 481 QIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLH 540
QIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLH
Sbjct: 481 QIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLH 540
Query: 541 IDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNT 600
IDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNT
Sbjct: 541 IDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNT 600
Query: 601 AGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGS 660
AGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGS
Sbjct: 601 AGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGS 660
Query: 661 MEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQC 720
MEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQC
Sbjct: 661 MEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQC 720
Query: 721 ECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGP 780
ECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGP
Sbjct: 721 ECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGP 780
Query: 781 LRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRL 840
LRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRL
Sbjct: 781 LRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRL 840
Query: 841 EISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRET 900
EISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRET
Sbjct: 841 EISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRET 900
Query: 901 SEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHC 960
SEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHC
Sbjct: 901 SEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHC 960
Query: 961 SSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTK 1020
SSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTK
Sbjct: 961 SSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTK 1020
Query: 1021 NISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL 1080
NISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL
Sbjct: 1021 NISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL 1080
Query: 1081 NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTL 1140
NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTL
Sbjct: 1081 NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTL 1140
Query: 1141 GKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCG 1200
GKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCG
Sbjct: 1141 GKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCG 1200
Query: 1201 FMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR 1260
FMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR
Sbjct: 1201 FMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR 1260
Query: 1261 FLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI 1306
FLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI
Sbjct: 1261 FLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI 1306
>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
Length = 1308
Score = 1595 bits (4130), Expect = 0.0
Identities = 762/1299 (58%), Positives = 982/1299 (75%), Gaps = 7/1299 (0%)
Query: 11 LTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWS 68
L LL + W+ +Y+CDDPL S L +FSSSS+L+ +H P A+LN R G GGWS
Sbjct: 12 LLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWS 71
Query: 69 PADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWT 128
P SN QWLQ+DLG R+E+TAVATQG YGSS+WVTSY LMFSD+G NWKQY+QEDSIW
Sbjct: 72 PLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWG 131
Query: 129 FAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSS 188
F+GN NADSVV+++L S++ARF+RF+PLEWNP G+IGMR+EV+GC+Y+S+V D DG+SS
Sbjct: 132 FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSS 191
Query: 189 LLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSK 248
LLYRF+QK +S +KD+ISLKFK+MQ DG+L H EG GDHITL+L++ RL L +N G++K
Sbjct: 192 LLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAK 251
Query: 249 ARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELS 308
+S+L + TLGSLLDDQHWHSVLI+R+GKQVNFTVD+H HF +GE + +++DYE+S
Sbjct: 252 LPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEIS 311
Query: 309 FGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT-GNVTFSCSEPQIVP 367
FGGIP PGK +F +NFHGC+ENLYYNGV+IIDLAK++K QI GNV+FSCS+PQ +P
Sbjct: 312 FGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMP 371
Query: 368 ITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRL 427
+TF+ SS SYL LP + +S +FQFRTWNK GLLL +EL SG +LL L G L+
Sbjct: 372 VTFL-SSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKS 430
Query: 428 VIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNS 487
+ + + ++I G LNDG WHSVS++A++N +++ +D + A AP QIYSG +
Sbjct: 431 NLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGT 490
Query: 488 YYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIK 547
YYFGGCPD S+C +P+ FQGCMRLI I + DLISVQQGSLGNFSDL ID C I
Sbjct: 491 YYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGIS 550
Query: 548 DRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYID 607
DRCLPNYCEHGG CSQSW+TF+CNC++T Y GATCHNSIYEQSCE Y+H+GNT+GF+YID
Sbjct: 551 DRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYID 610
Query: 608 SDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAV 667
SDGSGPL P +YCN+TE WT +QHN ++LTRVR NPE PYA +Y SMEQL+A
Sbjct: 611 SDGSGPLEPFLLYCNMTETA-WTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQAT 669
Query: 668 IDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDES 727
I+ +EHCEQE Y+C++SRL+N DGTP +WW+GR+NE YWGGS P +Q+C CGL+ +
Sbjct: 670 INRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGN 729
Query: 728 CLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDR 787
C+D Q++CNCDAD++EWTNDTG L++K+HLPVT+IVITDT R +SEAA+++GPL C GDR
Sbjct: 730 CIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDR 789
Query: 788 RFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSE 847
FWN+ SF TEASYLHFPTFH E SAD+SFFFKTTA SGVFLENLGI DFIR+E+ SP+
Sbjct: 790 SFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTV 849
Query: 848 ITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFR 907
+TF+ DVGNGP E+ VQSP+ NDNQWH+VR ERN+KE SLQVD L T+ +GH
Sbjct: 850 VTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVL 909
Query: 908 LQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSIC 967
LQLNSQLFVGGT++RQ+GFLGCIRSL LNG +DLEERA+VT V+PGC GHCSSYG +C
Sbjct: 910 LQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLC 969
Query: 968 HNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSS 1027
NGGKC E+ G+ CDCT S Y GPFC E+SA F +G+SV Y FQE Y ++KN S ++
Sbjct: 970 RNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAA 1029
Query: 1028 AIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNK-EETH 1086
+ + D S+E I SF TT+ PSLLLF++S ++++ V++ KNGSLQ+RY LNK +E
Sbjct: 1030 SFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPD 1089
Query: 1087 VFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTEN 1146
V D N A+ ++HH+ INRE + I++D R + S EF ++SL LG++ E+
Sbjct: 1090 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEH 1149
Query: 1147 LGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSD 1206
+D + A A A GF GC+S+VQ +H+APLKAAL + PVTV G +TESSC +D
Sbjct: 1150 SDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTD 1209
Query: 1207 VNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK 1266
+ HS +D G D+REPL NA++SDSAVIGG+IAVVIFI+ CI I R +YQ K
Sbjct: 1210 ATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQK 1268
Query: 1267 QSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYF 1305
+ ++ S+ K E ++ ++ ++E+++QN V+E ++EYF
Sbjct: 1269 RLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYF 1307
>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
Length = 1235
Score = 1508 bits (3903), Expect = 0.0
Identities = 727/1282 (56%), Positives = 937/1282 (73%), Gaps = 53/1282 (4%)
Query: 27 NYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWSPADSNAQQWLQMDLGN 84
NY+CDDPL S L +FSSSS+L+ +H P A+LN R G GGWSP SN QWLQ+DLG
Sbjct: 3 NYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 62
Query: 85 RVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHKLL 144
R+E+TAVATQG YGSS+WVTSY LMFSD+G NWKQY+QEDSIW F+GN NADSVV+++L
Sbjct: 63 RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 122
Query: 145 HSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDV 204
S++ARF+RF+PLEWNP G+IGMR+EV+GC+Y+S+V D DG+SSLLYRF+QK +S +KD+
Sbjct: 123 PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 182
Query: 205 ISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLL 264
ISLKFK+MQ DG+L H EG GDHITL+L++ RL L +N G++K +S+L + TLGSLL
Sbjct: 183 ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 242
Query: 265 DDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKK 324
DDQHWHSVLI+R+GKQVNFTVD+H HF +GE + +++DYE
Sbjct: 243 DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE------------------ 284
Query: 325 NFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTP 384
GNV+FSCS+PQ +P+TF+ SS SYL LP
Sbjct: 285 -----------------------------GNVSFSCSQPQSMPVTFL-SSRSYLALPDFS 314
Query: 385 QIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN 444
+ +S +FQFRTWNK GLLL +EL SG +LL L G L+ + + + ++I G
Sbjct: 315 GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 374
Query: 445 LNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLN 504
LNDG WHSVS++A++N +++ +D + A AP QIYSG +YYFGGCPD S+C +
Sbjct: 375 LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 434
Query: 505 PIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQS 564
P+ FQGCMRLI I + DLISVQQGSLGNFSDL ID C I DRCLPNYCEHGG CSQS
Sbjct: 435 PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 494
Query: 565 WTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVYCNIT 624
W+TF+CNC++T Y GATCHNSIYEQSCE Y+H+GNT+GF+YIDSDGSGPL P +YCN+T
Sbjct: 495 WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 554
Query: 625 EDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQEVAYHCRR 684
E WT +QHN ++LTRVR NPE PYA +Y SMEQL+A I+ +EHCEQE Y+C++
Sbjct: 555 ETA-WTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKK 613
Query: 685 SRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEW 744
SRL+N DGTP +WW+GR+NE YWGGS P +Q+C CGL+ +C+D Q++CNCDAD++EW
Sbjct: 614 SRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEW 673
Query: 745 TNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHF 804
TNDTG L++K+HLPVT+IVITDT R +SEAA+++GPL C GDR FWN+ SF TEASYLHF
Sbjct: 674 TNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHF 733
Query: 805 PTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQ 864
PTFH E SAD+SFFFKTTA SGVFLENLGI DFIR+E+ SP+ +TF+ DVGNGP E+ VQ
Sbjct: 734 PTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQ 793
Query: 865 SPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQK 924
SP+ NDNQWH+VR ERN+KE SLQVD L T+ +GH LQLNSQLFVGGT++RQ+
Sbjct: 794 SPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR 853
Query: 925 GFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDC 984
GFLGCIRSL LNG +DLEERA+VT V+PGC GHCSSYG +C NGGKC E+ G+ CDC
Sbjct: 854 GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDC 913
Query: 985 TNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSF 1044
T S Y GPFC E+SA F +G+SV Y FQE Y ++KN S +++ + D S+E I SF
Sbjct: 914 TFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSF 973
Query: 1045 VTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNK-EETHVFTIDADNFANRRMHHL 1103
TT+ PSLLLF++S ++++ V++ KNGSLQ+RY LNK +E V D N A+ ++HH+
Sbjct: 974 RTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHI 1033
Query: 1104 KINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAG 1163
INRE + I++D R + S EF ++SL LG++ E+ +D + A A A GF G
Sbjct: 1034 MINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTG 1093
Query: 1164 CMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSDVNAVTTVHSSSDPFGKT 1223
C+S+VQ +H+APLKAAL + PVTV G +TESSC +D + HS +D G
Sbjct: 1094 CLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTI 1153
Query: 1224 DEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHKQSHRTSQMKEKEYPENL 1283
D+REPL NA++SDSAVIGG+IAVVIFI+ CI I R +YQ K+ ++ S+ K E ++
Sbjct: 1154 DDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQKRLYKRSEAKRSENVDSA 1212
Query: 1284 DSSFRNEIDLQNTVSECKREYF 1305
++ ++E+++QN V+E ++EYF
Sbjct: 1213 EAVLKSELNIQNAVNENQKEYF 1234
>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
Length = 1288
Score = 1407 bits (3641), Expect = 0.0
Identities = 690/1279 (53%), Positives = 900/1279 (70%), Gaps = 13/1279 (1%)
Query: 10 VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67
VL LL + W +CD PLAS L +FSSSS+L+ +H P ++LN R G GGW
Sbjct: 11 VLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
Query: 68 SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127
+P SN QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 71 TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
Query: 128 TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187
F GN NADSVVH++L ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V FDG+S
Sbjct: 131 GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
Query: 188 SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247
+LLYR ++K + ++DVISLKFK+MQ +G+L H EGQ G+HITLEL KG+L LN G++
Sbjct: 191 ALLYRLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNA 250
Query: 248 KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307
K + + + TLGSLLDDQHWHSVLIE + QVNFTVDKHT HF+ KG++ LD+++E+
Sbjct: 251 KLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEI 310
Query: 308 SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT-GNVTFSCSEPQIV 366
SFGGIP PG+ F +K+FHGC+ENLYYNGV++ +LAK+ K QI GNV+FSC +PQ V
Sbjct: 311 SFGGIPTPGRSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTV 370
Query: 367 PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILR 426
P+TF+ SS SYL LPG D +SV+FQFRTWN+ G LL EL GSG+ +L L+ G L+
Sbjct: 371 PVTFL-SSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLK 429
Query: 427 LVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN 486
L + + + + G+ LNDG WHSVS +A+ + + + +DD+ A V I SG+
Sbjct: 430 LSLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA--VQPLVAVLIDSGD 487
Query: 487 SYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSI 546
+YYFGGC DN + S C +P+ FQGC+RLI I ++ D I VQQG+LG+F DL ID C I
Sbjct: 488 TYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 547
Query: 547 KDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYI 606
DRCLP+YCEHGG CSQSW TF C+C T YTG TCH+S+YEQSCE ++H+GN +G +YI
Sbjct: 548 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 607
Query: 607 DSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPY-AMALDYGGSMEQLE 665
D+DGSGPLGP VYCN+T D WT VQH + +RGA P A++ Y QL
Sbjct: 608 DADGSGPLGPFLVYCNMTADAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLR 667
Query: 666 AVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLD 725
+ ++ +E CEQ +A C +R ++ DGTP +WW+GR+NE H WGGS P Q+C CGL+
Sbjct: 668 SAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLE 727
Query: 726 ESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYG 785
+C+D Q++CNCDA ++EWT+DT LS K+HLPVTQIV+TD R +SEAA+ +GPL C G
Sbjct: 728 GNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRG 787
Query: 786 DRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSP 845
D+ FWN+ SF TE SYLHFP FH E +AD+ FFFKTT SGVF+ENLGI DFIR+E+ +P
Sbjct: 788 DQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAP 847
Query: 846 SEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGH 905
+E+TF+ DVGNGP E+ VQSP+ NDNQWH+VRAERN+K SLQVD LP+ + +GH
Sbjct: 848 TEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGH 907
Query: 906 FRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGS 965
RLQLNSQLF+GGT++RQ+GFLGCIRSL LNG +DLEERA VT GV PGC GHCS+YG
Sbjct: 908 VRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGH 967
Query: 966 ICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLS 1025
+C NGG+C EK G CDC S Y+GPFC E+SA F G+S+TY FQE Y +++N S
Sbjct: 968 LCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSL 1027
Query: 1026 SSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEET 1085
S+++ D ++E I LSF TT+ PSLLL+++S ++++ V+L NGSLQ+RY L++ +
Sbjct: 1028 VSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQN 1087
Query: 1086 -HVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVT 1144
FT D N A+ ++H +KINRE + ++++Q + S EF ++SL LGKV
Sbjct: 1088 PDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSTKKQVILSSGTEFNAVKSLILGKVL 1147
Query: 1145 ENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHG---TLTESSCGF 1201
E G D + +A GF GC+S+V++ APLKAALR + + VTV G + + G
Sbjct: 1148 EAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGA 1207
Query: 1202 MVDSDVNAVT-TVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR 1260
S + + + G DE EPL NA R DSAVIGGVIAVVIFI+ CI I R
Sbjct: 1208 ASGSPARELAPRLAGGAGRSGPADEGEPLVNADRRDSAVIGGVIAVVIFILLCITAIAIR 1267
Query: 1261 FLYQHK-QSHRTSQMKEKE 1278
Q K + S++ +KE
Sbjct: 1268 IYQQRKLRKENESKVSKKE 1286
>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
[Homo sapiens]
Length = 1288
Score = 1399 bits (3620), Expect = 0.0
Identities = 686/1279 (53%), Positives = 898/1279 (70%), Gaps = 13/1279 (1%)
Query: 10 VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67
VL LL + W +CD PLAS L +FSSSS+L+ +H P ++LN R G GGW
Sbjct: 11 VLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
Query: 68 SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127
+P SN QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 71 TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
Query: 128 TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187
F GN NADSVVH++L ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V FDG+S
Sbjct: 131 GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
Query: 188 SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247
+LLY ++K + ++DVISLKFK+MQ +G+L H EGQ G+HITLEL KG+L LN G++
Sbjct: 191 ALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNA 250
Query: 248 KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307
K + + + TLGSLLDDQHWHSVLIE + QVNFTVDKHT HF+ KG++ LD+++E+
Sbjct: 251 KLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEI 310
Query: 308 SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT-GNVTFSCSEPQIV 366
SFGGI PG+ F +K+FHGC+ENLYYNGV++ +LAK+ K QI GNV+FSC +PQ V
Sbjct: 311 SFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTV 370
Query: 367 PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILR 426
P+TF+ SS SYL LPG D +SV+FQFRTWN+ G LL EL GSG+ +L L+ G L+
Sbjct: 371 PVTFL-SSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLK 429
Query: 427 LVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN 486
L + + + + G+ LNDG WHSVS +A+ + + + +DD+ A V I SG+
Sbjct: 430 LSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA--VQPLVAVLIDSGD 487
Query: 487 SYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSI 546
+YYFGGC N + S C +P+ FQGC+RLI I ++ D I VQQG+LG+F DL ID C I
Sbjct: 488 TYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 547
Query: 547 KDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYI 606
DRCLP+YCEHGG CSQSW TF C+C T YTG TCH+S+YEQSCE ++H+GN +G +YI
Sbjct: 548 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 607
Query: 607 DSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPY-AMALDYGGSMEQLE 665
D+DGSGPLGP VYCN+T D WT V+H + +RGA P A++ Y QL
Sbjct: 608 DADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLR 667
Query: 666 AVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLD 725
A ++ +E CEQ +A C +R ++ DGTP +WW+GR+NE H WGGS P Q+C CGL+
Sbjct: 668 AAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLE 727
Query: 726 ESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYG 785
+C+D Q++CNCDA ++EWT+DT LS K+HLPVTQIV+TDT + +SEA + +GPL C G
Sbjct: 728 GNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRG 787
Query: 786 DRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSP 845
D+ FWN+ SF TE SYLHFP FH E +AD+ FFFKTT SGVF+ENLGI DFIR+E+ +P
Sbjct: 788 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAP 847
Query: 846 SEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGH 905
+E+TF+ DVGNGP E+ VQSP+ NDNQWH+VRAERN+K SLQVD LP+ + +GH
Sbjct: 848 TEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGH 907
Query: 906 FRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGS 965
RLQLNSQLF+GGT++RQ+GFLGCIRSL LNG +DLEERA VT GV PGC GHCS+YG
Sbjct: 908 VRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGH 967
Query: 966 ICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLS 1025
+C NGG+C EK G CDC S Y+GPFC E+SA F G+S+TY FQE Y +++N S
Sbjct: 968 LCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSL 1027
Query: 1026 SSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEET 1085
S++Y D ++E I LSF TT++PSLLL+++S ++++ V+L NGSLQ+RY L++ +
Sbjct: 1028 VSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQN 1087
Query: 1086 -HVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVT 1144
FT D N A+ ++H +KINRE + ++++Q + S EF ++SL LGKV
Sbjct: 1088 PDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL 1147
Query: 1145 ENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHG---TLTESSCGF 1201
E G D + +A GF GC+S+V++ APLKAALR + + VTV G + + G
Sbjct: 1148 EAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGA 1207
Query: 1202 MVDSDVNAVT-TVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR 1260
S + + + G DE EPL NA R DSAV+GGVIAVVIFI+ CI I R
Sbjct: 1208 ASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR 1267
Query: 1261 FLYQHK-QSHRTSQMKEKE 1278
Q K + S++ +KE
Sbjct: 1268 IYQQRKLRKENESKVSKKE 1286
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
Length = 1331
Score = 1338 bits (3463), Expect = 0.0
Identities = 662/1316 (50%), Positives = 901/1316 (68%), Gaps = 48/1316 (3%)
Query: 25 ATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWSPADSNAQQWLQMDL 82
+T+ CD+PL S L +AFSSSS ++G++SP A++N R G GGWSP+DS+ QWLQ+D
Sbjct: 30 STSQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDF 89
Query: 83 GNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHK 142
GNR +I+A+ATQGRY SSDWVT Y +++SDTGRNWK Y Q+ +IW F GN+N+D VV H+
Sbjct: 90 GNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHE 149
Query: 143 LLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLK 202
L H + AR+VR VPL+WN G+IG+R+EVYGCSY +DV +FDG L YRF K M TLK
Sbjct: 150 LQHPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLK 209
Query: 203 DVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGS 262
DVI+L FK+ + +GV+ HGEGQ+GD+ITLEL+K +L L LNLG ++ S GS
Sbjct: 210 DVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGS 269
Query: 263 LLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFL 322
LLDD HWHSV+IER G+ +N T+D+ QHFRT GE D LD+DYE++FGGIP GKP +
Sbjct: 270 LLDDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSS 329
Query: 323 KKNFHGCIENLYYNGVNIIDLAKRRKHQ-IYTGNVTFSCSEPQIVPITFVNSSGSYLLLP 381
+KNF GC+E++ YNGVNI DLA+R+K + GN++FSC EP VP+ F ++ SYL +P
Sbjct: 330 RKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFF--NATSYLEVP 387
Query: 382 GTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLE----GGILRLVIQKMTERVA 437
G D SVSFQFRTWN +GLL+ + ++ G + + L G + + KM++
Sbjct: 388 GRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQ--I 445
Query: 438 EILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNL 497
+I +GS LNDG WH V A+ N LT+D + A ++ +Q+ +G Y+FGG + +
Sbjct: 446 DISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQM 505
Query: 498 TDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEH 557
+S +FQGCM+LI +D+Q +L V Q G+F+++ ID+C+I DRC+PN+CEH
Sbjct: 506 NNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEH 565
Query: 558 GGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPL 617
GG CSQ+W +F C C +T Y+GATCHNSIYE SCE Y+H G T+ +++ID DGSGPLGPL
Sbjct: 566 GGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPL 625
Query: 618 QVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQE 677
+VYCN+TEDK+WT V H+ T V G NPEK L Y SM+Q+ A+ D +E+CEQ
Sbjct: 626 KVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQY 685
Query: 678 VAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNC 737
V+Y C+ SRLLNTPDG+P+TWW+G++NE+H YWGGS PG+Q+C CG++ +C D +++CNC
Sbjct: 686 VSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNC 745
Query: 738 DADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYT 797
DAD +W D GFLS+KDHLPV+Q+V+ DTDR SEA +GPLRC GDR +WNA SF
Sbjct: 746 DADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPN 805
Query: 798 EASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNG 857
+SYLHF TF E SADISF+FKT GVFLEN+G +DFI+LE+ S +E++F+ DVGNG
Sbjct: 806 PSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNG 865
Query: 858 PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917
PVE+VV+SP+ LND+QWH V AERN+K+ SLQVD LP+ R+ EGH RL+L SQLFVG
Sbjct: 866 PVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVG 925
Query: 918 GTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKH 977
G Q+GFLGCIRSL +NG +DLEERAKVTSG GC GHC+SYG+ C NGGKC+E++
Sbjct: 926 GAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERY 984
Query: 978 NGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSK 1037
+GY CDC+N+ Y+G FC K+V A FE G + Y FQ P N SSS + D+AP +
Sbjct: 985 HGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP---ATNARDSSSRV--DNAPDQ 1039
Query: 1038 EN---------IALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL-NKEETHV 1087
+N I SF TT+AP +LL+I+S + DF+ VL+ GSLQ+RY+L E +
Sbjct: 1040 QNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYN 1099
Query: 1088 FTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNF--SPEVEFRVIRSLTLGKVTE 1145
+D N AN + H + I R + + +++D +SY+ S + F +SL LGKV E
Sbjct: 1100 IDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIE 1159
Query: 1146 NLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATV-APVTVHGTLTESSCGFMVD 1204
+D E+ K N GF GC+S VQ+N IAPLKAALR A V + G L ES+CG
Sbjct: 1160 TGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCG---- 1215
Query: 1205 SDVNAVTTVHSSSDPFG-------------KTDEREPLTNAVRSDSAVIGGVIAVVIFII 1251
+ ++ + S++DP+ + + + N V +SA+IGGVIAVVIF I
Sbjct: 1216 ASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTI 1275
Query: 1252 FCIIGIMTRFLYQHKQSHRTSQMKEKEYPENLDSS-FRNEIDLQNTVSECKREYFI 1306
C + + R++++HK ++ T++ K E E+ D++ N+ + T+ E K+E+ I
Sbjct: 1276 LCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI 1331
>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
[Homo sapiens]
Length = 1207
Score = 1074 bits (2778), Expect = 0.0
Identities = 516/911 (56%), Positives = 665/911 (72%), Gaps = 8/911 (0%)
Query: 10 VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67
VL LL + W +CD PLAS L +FSSSS+L+ +H P ++LN R G GGW
Sbjct: 11 VLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
Query: 68 SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127
+P SN QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 71 TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
Query: 128 TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187
F GN NADSVVH++L ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V FDG+S
Sbjct: 131 GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
Query: 188 SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247
+LLY ++K + ++DVISLKFK+MQ +G+L H EGQ G+HITLEL KG+L LN G++
Sbjct: 191 ALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNA 250
Query: 248 KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307
K + + + TLGSLLDDQHWHSVLIE + QVNFTVDKHT HF+ KG++ LD+++E+
Sbjct: 251 KLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEI 310
Query: 308 SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSEPQIV 366
SFGGI PG+ F +K+FHGC+ENLYYNGV++ +LAK+ K QI GNV+FSC +PQ V
Sbjct: 311 SFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTV 370
Query: 367 PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILR 426
P+TF+ SS SYL LPG D +SV+FQFRTWN+ G LL EL GSG+ +L L+ G L+
Sbjct: 371 PVTFL-SSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLK 429
Query: 427 LVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN 486
L + + + + G+ LNDG WHSVS +A+ + + + +DD+ A V I SG+
Sbjct: 430 LSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA--VQPLVAVLIDSGD 487
Query: 487 SYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSI 546
+YYFGGC N + S C +P+ FQGC+RLI I ++ D I VQQG+LG+F DL ID C I
Sbjct: 488 TYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 547
Query: 547 KDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYI 606
DRCLP+YCEHGG CSQSW TF C+C T YTG TCH+S+YEQSCE ++H+GN +G +YI
Sbjct: 548 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 607
Query: 607 DSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPY-AMALDYGGSMEQLE 665
D+DGSGPLGP VYCN+T D WT V+H + +RGA P A++ Y QL
Sbjct: 608 DADGSGPLGPFLVYCNMT-DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLR 666
Query: 666 AVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLD 725
A ++ +E CEQ +A C +R ++ DGTP +WW+GR+NE H WGGS P Q+C CGL+
Sbjct: 667 AAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLE 726
Query: 726 ESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYG 785
+C+D Q++CNCDA ++EWT+DT LS K+HLPVTQIV+TDT + +SEA + +GPL C G
Sbjct: 727 GNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRG 786
Query: 786 DRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSP 845
D+ FWN+ SF TE SYLHFP FH E +AD+ FFFKTT SGVF+ENLGI DFIR+E+ +P
Sbjct: 787 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAP 846
Query: 846 SEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGH 905
+E+TF+ DVGNGP E+ VQSP+ NDNQWH+VRAERN+K SLQVD LP+ + +GH
Sbjct: 847 TEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGH 906
Query: 906 FRLQLNSQLFV 916
RLQLNSQLF+
Sbjct: 907 VRLQLNSQLFI 917
Score = 204 bits (518), Expect = 6e-52
Identities = 117/288 (40%), Positives = 172/288 (59%), Gaps = 6/288 (2%)
Query: 997 EVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFI 1056
E+SA F G+S+TY FQE Y +++N S S++Y D ++E I LSF TT++PSLLL++
Sbjct: 918 EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
Query: 1057 NSSSQDFVVVLLCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRELTIQ 1115
+S ++++ V+L NGSLQ+RY L++ + FT D N A+ ++H +KINRE + ++
Sbjct: 978 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
Query: 1116 MDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAP 1175
++Q + S EF ++SL LGKV E G D + +A GF GC+S+V++ AP
Sbjct: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
Query: 1176 LKAALRHATVAPVTVHG---TLTESSCGFMVDSDVNAVT-TVHSSSDPFGKTDEREPLTN 1231
LKAALR + + VTV G + + G S + + + G DE EPL N
Sbjct: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
Query: 1232 AVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK-QSHRTSQMKEKE 1278
A R DSAV+GGVIAVVIFI+ CI I R Q K + S++ +KE
Sbjct: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKE 1205
Score = 50.4 bits (119), Expect = 1e-05
Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 44/229 (19%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAI 852
V+F + SYL P E ++F F+T +G L F L+ S S + F
Sbjct: 372 VTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLL-------FGELQRGSGSFVLFLK 424
Query: 853 DVGNGPVELVV----QSP------SLLNDNQWHYVRAERNLKETSLQVDN------LPRS 896
D G ++L + QSP + LND QWH V ++ VD+ L
Sbjct: 425 D---GKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV 481
Query: 897 TRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMD--LEERAKVTS---- 950
++ + +F L + G S GF GC+R + + + +D L ++ + S
Sbjct: 482 LIDSGDTYYFGGCLGNSSG-SGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
Query: 951 -----GVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFC 994
G+ C S C +GG+C + + + CDC + Y G C
Sbjct: 541 QIDSCGITDRC------LPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
Score = 42.4 bits (98), Expect = 0.003
Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 22/148 (14%)
Query: 815 ISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAIDVGNG-------PVELVVQSP 866
IS FK +G+ L G + I LE+ ++ F ++ GN PV L + S
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIK-GKLVFFLNSGNAKLPSTIAPVTLTLGS- 265
Query: 867 SLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSS----- 921
LL+D WH V E + + VD + + + L LN ++ GG S
Sbjct: 266 -LLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGILSPGRSR 322
Query: 922 --RQKGFLGCIRSLHLNGQKMDLEERAK 947
+K F GC+ +L+ NG +D+ E AK
Sbjct: 323 AFTRKSFHGCLENLYYNG--VDVTELAK 348
>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
Length = 1384
Score = 938 bits (2424), Expect = 0.0
Identities = 510/1340 (38%), Positives = 761/1340 (56%), Gaps = 93/1340 (6%)
Query: 6 RLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVG 63
RL +L SG G Y CD+ L L + +SS + +P A+L+ G
Sbjct: 5 RLFCILLAAVSGAEGWGY----YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---G 57
Query: 64 TGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQE 123
GWSP + WLQ+DL + I AVATQG + S DWVT Y L++ D +W + Q
Sbjct: 58 ISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQR 117
Query: 124 DSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADF 183
TF GN+N +VV H L AR++R VPL WNP GKIG+R+ +YGC YK+D+ F
Sbjct: 118 GHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYF 177
Query: 184 DGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLN 243
DG ++ YRF + + +L DV + FK+ + DG+L H EG +GD++TLEL+ L LH++
Sbjct: 178 DGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMS 237
Query: 244 LGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDI 303
LG S + + + G +L+DQHWH V ++R G+ VNFT+D + Q F G+ + L++
Sbjct: 238 LGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNL 297
Query: 304 DYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSE 362
D E+ GG+ + + NF GCIEN+ +N VNI DLA RR +I + G V F C +
Sbjct: 298 DTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLD 357
Query: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
P PI F +++ +PG P+ L+VSF+FRTW+ GLLL + L +G G + L+L
Sbjct: 358 PVPHPINF-GGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSE 416
Query: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482
G + + I + + + G LNDG WH V+ A+ N +++DD S + I
Sbjct: 417 GQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLI 476
Query: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHID 542
+G SY+FGGCP + C + AF GCM L+ +D Q +L V+ LG ++++ D
Sbjct: 477 RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536
Query: 543 LCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAG 602
C I DRC PN CEH G C QSW F C C T Y G TCH +Y++SCE YR G T+G
Sbjct: 537 TCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSG 596
Query: 603 FFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDY-GGSM 661
F ID DGSGPL P VYC+I E++ WT V+H+ TRV G++ E+P+ A+ Y S
Sbjct: 597 NFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASW 656
Query: 662 EQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCE 721
E++ A+ + S+HCEQ + + C SRLLNT G P+++WIGR+ E+H YWGGS PG+Q+C
Sbjct: 657 EEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCA 716
Query: 722 CGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPL 781
CGLD SC+D +CNCDAD+ +W D G L+F DHLPVTQ+VI DT+RS SEA + + PL
Sbjct: 717 CGLDRSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPL 776
Query: 782 RCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLG------IK 835
RCYGDR WN +SF+T A+ L FP A S D+SF+F+T+A SGVFLEN+G +
Sbjct: 777 RCYGDRNSWNTISFHTGAA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRR 835
Query: 836 DFIRLEISSPSEITFAIDVGNGPVELVVQSPSL-LNDNQWHYVRAERNLKETSLQVDNLP 894
++R+E+++ ++ FA DVGNG L V S ND++WH VRAE N+K+ L+VD+ P
Sbjct: 836 PYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRP 895
Query: 895 RSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRP 954
R + + ++ + L+VG +++ F+GC+R++ LNG ++LE RA + G P
Sbjct: 896 WVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSP 955
Query: 955 GCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQE 1014
C GHC+ C +GG+CVE+++ Y CDC + ++GP+C ++ FE GT + Y Q
Sbjct: 956 NCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQS 1015
Query: 1015 PYPVTKNISLSSSAIYTDSAPSKE------------------------------------ 1038
++ + S + + P E
Sbjct: 1016 ---ALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGY 1072
Query: 1039 ----------NIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVF 1088
++ SF T+ AP++LL+++S +D++ VL+ +G+LQ+RY L +V+
Sbjct: 1073 RGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG-TSPYVY 1131
Query: 1089 TIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRV--IRSLTLGKVTEN 1146
+ + + H + I R R L IQ+D FS V+ ++ ++L LG+V E
Sbjct: 1132 QLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMET 1191
Query: 1147 LGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVT--------VHGTLTESS 1198
+D E+ + N GF+GC+S V++N++APLK R T P+T V G L+ES+
Sbjct: 1192 GVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFR--TPRPMTAELAEALRVQGELSESN 1249
Query: 1199 CGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIM 1258
CG M V+ V DP+ + P + + ++G ++A F++ ++G++
Sbjct: 1250 CGAM----PRLVSEVPPELDPWYLPPD-FPYYHDEGWVAILLGFLVA---FLLLGLVGML 1301
Query: 1259 TRFLYQ---HKQSHRTSQMK 1275
F Q +K S+ T++ K
Sbjct: 1302 VLFYLQNHRYKGSYHTNEPK 1321
>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 944
Score = 548 bits (1413), Expect = e-155
Identities = 252/457 (55%), Positives = 333/457 (72%), Gaps = 1/457 (0%)
Query: 693 GTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEWTNDTGFLS 752
GTP +WW+GR+NE H WGGS P Q+C CGL+ +C+D Q++CNCDA ++EWT+DT LS
Sbjct: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
Query: 753 FKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHFPTFHAEFS 812
K+HLPVTQIV+TD + +SEA + +GPL C GD+ FWN+ SF TE SYLHFP FH E +
Sbjct: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
Query: 813 ADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDN 872
AD+ FFFKTT SGVF+ENLGI DFIR+E+ +P+E+TF+ DVGNGP E+ VQSP+ NDN
Sbjct: 548 ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
Query: 873 QWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRS 932
QWH+VRAERN+K SLQVD LP+ + +GH RLQLNSQLF+GGT++RQ+GFLGCIRS
Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667
Query: 933 LHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGP 992
L LNG +DLEERA V GV PGC GHCS+YG +C NGG+C EK G CDC S Y+GP
Sbjct: 668 LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
Query: 993 FCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSL 1052
FC E+SA F G+S+TY FQE Y +++N S S+++ D ++E I LSF TT+ PSL
Sbjct: 728 FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787
Query: 1053 LLFINSSSQDFVVVLLCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRE 1111
LL+++S ++++ V+L NGSLQ+RY L++ + FT D N A+ ++H +KINRE
Sbjct: 788 LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847
Query: 1112 LTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLG 1148
+ ++++Q + S EF ++SL LGKV G
Sbjct: 848 VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
Score = 192 bits (487), Expect = 2e-48
Identities = 84/151 (55%), Positives = 106/151 (70%)
Query: 475 PDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLG 534
P + W + C N + S C +P+ FQGC+RLI I ++ D I VQQG+LG
Sbjct: 169 PGAAWREGLQRRGRLLVRCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALG 228
Query: 535 NFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVY 594
+F DL ID C I DRCLP+YCEHGG CSQSW TF C+C T YTG TCH+S+YEQSCE +
Sbjct: 229 SFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAH 288
Query: 595 RHQGNTAGFFYIDSDGSGPLGPLQVYCNITE 625
+H+GN +G +YID+DGSGPLGP VYCN+T+
Sbjct: 289 KHRGNPSGLYYIDADGSGPLGPFLVYCNMTD 319
Score = 57.4 bits (137), Expect = 9e-08
Identities = 32/59 (54%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1221 GKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK-QSHRTSQMKEKE 1278
G DE EPL NA R DSAVIGGVIAV IFI+ CI I R Q K + S++ +KE
Sbjct: 884 GPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKE 942
Score = 41.6 bits (96), Expect = 0.005
Identities = 34/150 (22%), Positives = 55/150 (36%), Gaps = 30/150 (20%)
Query: 446 NDGLWHSVSINARRNRITLTLDD--EAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCL 503
ND WH V +L +D + PAP V++ + + GG
Sbjct: 605 NDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ------ 658
Query: 504 NPIKAFQGCMRLIFIDNQPKDLIS-------VQQGSLGNFSDLHIDLCSIKDRCLPNYCE 556
+ F GC+R + ++ DL V+ G G+ S + C
Sbjct: 659 ---RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYG------------HLCR 703
Query: 557 HGGSCSQSWTTFYCNCSDTSYTGATCHNSI 586
+GG C + C+C+ ++Y G C N I
Sbjct: 704 NGGRCREKRRGVTCDCAFSAYDGPFCSNEI 733
Score = 36.2 bits (82), Expect = 0.21
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 17/88 (19%)
Query: 918 GTSSRQKGFLGCIRSLHLNGQKMD--LEERAKVTS---------GVRPGCPGHCSSYGSI 966
G S GF GC+R + + + +D L ++ + S G+ C S
Sbjct: 195 GCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRC------LPSY 248
Query: 967 CHNGGKCVEKHNGYLCDCTNSPYEGPFC 994
C +GG+C + + + CDC + Y G C
Sbjct: 249 CEHGGECSQSWDTFSCDCLGTGYTGETC 276
Score = 35.0 bits (79), Expect = 0.47
Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 17/141 (12%)
Query: 209 FKSMQGDGVLFHGEGQRGDHITLELQKG-RLALHLNLGDSKARLSSSLPSATLGSLLDDQ 267
FK+ GV G D I +EL+ + ++G+ ++ P+ +D
Sbjct: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607
Query: 268 HWHSVLIERVGKQVNFTVDKHTQHFRTKGETD--ALDIDYELSFGGIPVPGKPGTFLKKN 325
WH V ER K + VD+ Q + L ++ +L GG ++
Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT-------RQRG 660
Query: 326 FHGCIENLYYNGVNIIDLAKR 346
F GCI +L NGV +DL +R
Sbjct: 661 FLGCIRSLQLNGV-ALDLEER 680
>gi|239743729 PREDICTED: similar to contactin associated
protein-like 3B [Homo sapiens]
Length = 380
Score = 427 bits (1099), Expect = e-119
Identities = 206/344 (59%), Positives = 262/344 (76%), Gaps = 2/344 (0%)
Query: 10 VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67
VL LL + W +CD PLAS L +FSSSS+L+ +H P ++LN R G GGW
Sbjct: 11 VLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
Query: 68 SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127
+P SN QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 71 TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
Query: 128 TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187
F GN NADSVVH++L ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V FDG+S
Sbjct: 131 GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
Query: 188 SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247
+LLY ++K + ++DVISLKFK+MQ +G+L H EGQ G+HITLEL K +L LN G++
Sbjct: 191 ALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNA 250
Query: 248 KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307
K + + + TLGSLLDDQHWHSVLIE + QVNFTVDKHT HF+ KG++ LD+++E+
Sbjct: 251 KLPSTIAPVTLTLGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEI 310
Query: 308 SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI 351
SFGGIP PG+ F +K+FHGC+ENLYYNGV++ +LAK+ K QI
Sbjct: 311 SFGGIPTPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQI 354
Score = 41.6 bits (96), Expect = 0.005
Identities = 42/148 (28%), Positives = 66/148 (44%), Gaps = 22/148 (14%)
Query: 815 ISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAIDVGNG-------PVELVVQSP 866
IS FK +G+ L G + I LE+ ++ F ++ GN PV L + S
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIK-RKLVFFLNSGNAKLPSTIAPVTLTLGS- 265
Query: 867 SLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSS----- 921
LL+D WH V E + + VD + + + L LN ++ GG +
Sbjct: 266 -LLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGIPTPGRSR 322
Query: 922 --RQKGFLGCIRSLHLNGQKMDLEERAK 947
+K F GC+ +L+ NG +D+ E AK
Sbjct: 323 AFTRKSFHGCLENLYYNG--VDVTELAK 348
Score = 32.3 bits (72), Expect = 3.0
Identities = 29/132 (21%), Positives = 52/132 (39%), Gaps = 7/132 (5%)
Query: 391 VSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQ---KMTERVAEILT--GSNL 445
+S +F+ +G+LL E G+ L ++ ++ + K+ +A + GS L
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGSLL 267
Query: 446 NDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNP 505
+D WHSV I ++ T+D + FGG P
Sbjct: 268 DDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGRSRAFTR- 326
Query: 506 IKAFQGCMRLIF 517
K+F GC+ ++
Sbjct: 327 -KSFHGCLENLY 337
>gi|169184330 PREDICTED: novel protein similar to contactin associated
protein-like 3 (CNTNAP3) [Homo sapiens]
Length = 291
Score = 197 bits (502), Expect = 4e-50
Identities = 115/288 (39%), Positives = 170/288 (59%), Gaps = 6/288 (2%)
Query: 997 EVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFI 1056
++SA F G+S+TY FQE Y +++N S S+++ D ++E I LSF TT+ PSLLL++
Sbjct: 2 KISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 61
Query: 1057 NSSSQDFVVVLLCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRELTIQ 1115
+S ++++ V+L NGSLQ+RY L++ + FT D N A+ ++H +KINRE + ++
Sbjct: 62 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 121
Query: 1116 MDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAP 1175
++Q + S EF ++SL LGKV E G D + +A GF GC+S+V++ AP
Sbjct: 122 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAAP 181
Query: 1176 LKAALRHATVAPVTVHG---TLTESSCGFMVDSDVNAVT-TVHSSSDPFGKTDEREPLTN 1231
LKAALR + + VTV G + + G S + + + G DE EPL N
Sbjct: 182 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 241
Query: 1232 AVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK-QSHRTSQMKEKE 1278
A R DSAVIGGVIAV IFI+ CI I R Q K + S++ +KE
Sbjct: 242 ADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKE 289
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 127 bits (320), Expect = 5e-29
Identities = 130/475 (27%), Positives = 217/475 (45%), Gaps = 73/475 (15%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGI-KDFIRLEISSPSEITFA 851
V+F T++SY+ T A S + F FKTT+L G+ L N G DFI +E+ + +
Sbjct: 907 VTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYV 965
Query: 852 IDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLN 911
D+GNG + S LNDNQWH V R+ + +T+ T+ G L L
Sbjct: 966 FDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITA--GARNLDLK 1023
Query: 912 SQLFVGGTSSR-----------QKGFLGCIRSLHLNGQKMDLEERAKVTSG-VRPGCPGH 959
S L++GG + ++GF GC+ S+ LNG+ DL A +G + GC G
Sbjct: 1024 SDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGP 1083
Query: 960 CSS-YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMF-----Q 1013
++ C N G C+++ +G+ CDC+ + + GP C + GT TY+F Q
Sbjct: 1084 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN-------DPGT--TYIFSKGGGQ 1134
Query: 1014 EPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSS--QDFVVVLLCKN 1071
Y N S+ A + +A+ F T Q ++L+ ++SSS D+ + L
Sbjct: 1135 ITYKWPPNDRPSTRA---------DRLAIGFSTVQKEAVLVRVDSSSGLGDY-LELHIHQ 1184
Query: 1072 GSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVE 1131
G + V++++ ++ + +A + + H ++ R G T+Q+D P +E
Sbjct: 1185 GKIGVKFNVGTDDIAIEESNA-IINDGKYHVVRFTRSGGNATLQVDSW--------PVIE 1235
Query: 1132 -FRVIRSLTL--GKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLK-AALRHATVAP 1187
+ R LT+ + T +G K F G +S + YN + L AA A +A
Sbjct: 1236 RYPAGRQLTIFNSQATIIIG-----GKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAI 1290
Query: 1188 V-------TVHGTLTESSCGFMVDSDVN-----AVTTVHSSSDPFGKTDEREPLT 1230
V V ++T S + S+++ TT+ +S+ GK +EP++
Sbjct: 1291 VGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS 1345
Score = 127 bits (318), Expect = 9e-29
Identities = 122/457 (26%), Positives = 197/457 (43%), Gaps = 49/457 (10%)
Query: 174 CSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQ-RGDHITLE 232
C ++ V +DG + + +M T + +SL+F+S + G+L + D + LE
Sbjct: 712 CEREATVLSYDGSMFMKIQL-PVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLE 770
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATL--GSLLDDQHWHSVLIERVGKQVNFTVDKHTQ 290
L GR+ L +NL + +SS TL G L+D WH+V + R GK + TVD Q
Sbjct: 771 LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQ-Q 829
Query: 291 HFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQ 350
+ D +++ GI + + + NF G +++L +NG+ IDL K
Sbjct: 830 AMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDID 889
Query: 351 IYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELS 410
N F P+TF S SY+ L + + FQF+T + DGL+L
Sbjct: 890 YCELNARFGFRNIIADPVTFKTKS-SYVALATLQAYTSMHLFFQFKTTSLDGLILYNS-G 947
Query: 411 EGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN---LNDGLWHSVSINARRNRI-TLTL 466
+G+ +++ L G L V A ++ GS+ LND WH+V I+ + + T+ +
Sbjct: 948 DGNDFIVVELVKGYLHYVFD--LGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKI 1005
Query: 467 DDEAAPPAPDSTWVQIYSG-------NSYYFGGCPDNLTDS--QCLNPIKAFQGCMRLIF 517
D + QI +G + Y GG S + ++ + FQGC+ +
Sbjct: 1006 DTKIT--------TQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVD 1057
Query: 518 IDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSY 577
++ + DLIS +L + C + C + G C Q W F C+CS TS+
Sbjct: 1058 LNGRLPDLIS---DALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSF 1114
Query: 578 TGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPL 614
+G C N G YI S G G +
Sbjct: 1115 SGPLC----------------NDPGTTYIFSKGGGQI 1135
Score = 118 bits (296), Expect = 3e-26
Identities = 117/453 (25%), Positives = 193/453 (42%), Gaps = 73/453 (16%)
Query: 180 VADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLA 239
+A F G Y +Q + + D I+L FK++Q +G++ H G+ D++ L L+ G ++
Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 341
Query: 240 LHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQ--------VNFTVDKH-TQ 290
L +NLG +L G +D WH V + R +Q V +VD T
Sbjct: 342 LVINLGSGAFE---ALVEPVNGKF-NDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397
Query: 291 HFRTKGETDALDIDYELSFGGIPVPGK-PGTFLKKNFHGCIENLYYNGVNI-IDLAKRRK 348
T+ + L D GG P PG+ + NF GC++ + Y ++ ++L++ K
Sbjct: 398 TGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 457
Query: 349 H-----QIYTGNVTFSCSEPQIV-PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDG 402
+I+ G V F C + PITF + S++ LP S+SF FRT +G
Sbjct: 458 QGDPKMKIH-GVVAFKCENVATLDPITF-ETPESFISLPKWNAKKTGSISFDFRTTEPNG 515
Query: 403 LLL-----------------------STELSEGSGTLLLSLEGGILRLVIQKMTERVAEI 439
L+L + E+ +G LLL + G ++ I+ + ++V
Sbjct: 516 LILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIK--IKALLKKV--- 570
Query: 440 LTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTD 499
NDG W+ V T++++ P + + Y GG P+N
Sbjct: 571 ------NDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAG 624
Query: 500 --------SQCLNPIKAFQGCMRLIFIDNQPKDL--ISVQQGSLGNFSDLHIDLCSIKDR 549
+ LN + GC+R +FID Q KD+ ++ Q + G +
Sbjct: 625 LVFPTEVWTALLN--YGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAK---P 679
Query: 550 CLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATC 582
CL N C++ G C W + C+CS T Y G +C
Sbjct: 680 CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 712
Score = 109 bits (273), Expect = 2e-23
Identities = 97/416 (23%), Positives = 187/416 (44%), Gaps = 53/416 (12%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLG-------------IK-DFI 838
++F T S++ P ++A+ + ISF F+TT +G+ L + G IK DF
Sbjct: 482 ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 541
Query: 839 RLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTR 898
+E+ + +D+G+G +++ + ND +W++V +R+ + ++ V+ L T
Sbjct: 542 AIEMLD-GHLYLLLDMGSGTIKIKALLKKV-NDGEWYHVDFQRDGRSGTISVNTL--RTP 597
Query: 899 ETSEEGHFRLQLNSQLFVGG---------------TSSRQKGFLGCIRSLHLNGQKMDLE 943
T+ L L+ +L++GG T+ G++GCIR L ++GQ D+
Sbjct: 598 YTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIR 657
Query: 944 ERAKV--TSGVRPGCPGHCSS--YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVS 999
+ A+V T+GV+P C + + C N G C + N Y+CDC+ + Y G C++E +
Sbjct: 658 QMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREAT 717
Query: 1000 AVFEAGTSVTYMFQE-PYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINS 1058
+ G+ MF + PV + ++ S + + + A +L L +++
Sbjct: 718 VLSYDGS----MFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDA 773
Query: 1059 SSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQ 1118
V L C +R + N + N + H +++ R G+ L + +D
Sbjct: 774 GRVKLTVNLDC------IRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDD 827
Query: 1119 QLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIA 1174
Q ++ + + ++ G +TE L S + F G + S+ +N +A
Sbjct: 828 QQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPS-----NFIGHLQSLTFNGMA 878
Score = 80.5 bits (197), Expect = 1e-14
Identities = 86/351 (24%), Positives = 146/351 (41%), Gaps = 46/351 (13%)
Query: 798 EASYLHFPTFHAEFSADISFFFKTTALSGVFL--ENLGIKDFIRLEISSPSEITFAIDVG 855
E + FP ++A +++SF KT + G+ L ++ G DF+ L ++ + + +
Sbjct: 37 EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96
Query: 856 NG-PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQL 914
P L+ +P +ND WH VR R + T+L +D + E + + + S L
Sbjct: 97 CAEPATLLADTP--VNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGL 153
Query: 915 FVGG---------------TSSRQKGFLGCIRSLHLNGQKMDLEERAKV-------TSGV 952
FVGG + ++ F G IR + +N ++ + +V SG
Sbjct: 154 FVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGG 213
Query: 953 RPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAV-----FEAGTS 1007
C G +C NGG C + +CDC+ + + G C +E + V G
Sbjct: 214 GSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQ 273
Query: 1008 VTYMFQEPYPVTKNIS------LSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQ 1061
+E Y T S LS + I + S + I LSF T Q L+L S+
Sbjct: 274 GKSKGKEEYIATFKGSEYFCYDLSQNPIQS----SSDEITLSFKTLQRNGLMLHTGKSA- 328
Query: 1062 DFVVVLLCKNGSLQVRYHLNKEETHVFTIDAD-NFANRRMHHLKINREGRE 1111
D+V + L KNG++ + +L + F + H +K+ R R+
Sbjct: 329 DYVNLAL-KNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQ 378
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/149 (26%), Positives = 72/149 (48%), Gaps = 19/149 (12%)
Query: 812 SADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPS-LLN 870
S +I+ FKT +G+ L D++ L + + + ++ I++G+G E +V+ + N
Sbjct: 305 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKFN 363
Query: 871 DNQWHYVRAERNLKETS--------LQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSR 922
DN WH V+ RNL++ S + VD + +T T E+ + L + +VGG+ S
Sbjct: 364 DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYVGGSPST 422
Query: 923 --------QKGFLGCIRSLHLNGQKMDLE 943
F+GC++ + + LE
Sbjct: 423 ADLPGSPVSNNFMGCLKEVVYKNNDVRLE 451
Score = 52.4 bits (124), Expect = 3e-06
Identities = 86/385 (22%), Positives = 145/385 (37%), Gaps = 74/385 (19%)
Query: 808 HAEFSADISFFFKTTALSGVFLENLG--IKDFIRLEISSPS-EITFAIDV-------GNG 857
H E + D+S F++ G+ + D +RLE+ + ++T +D G
Sbjct: 736 HTE-AEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKG 794
Query: 858 PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917
P L LNDN+WH VR R K L VD+ T + + + H RL+ ++ + G
Sbjct: 795 PETLFAGYN--LNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN-IETG 850
Query: 918 GTSSRQ------KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGG 971
+ R+ F+G ++SL NG +Y +C NG
Sbjct: 851 IITERRYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNG- 886
Query: 972 KCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYT 1031
+ +C E++A F + PVT S A+ T
Sbjct: 887 ------------------DIDYC--ELNARFGFRNIIAD------PVTFKTKSSYVALAT 920
Query: 1032 DSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTID 1091
A + ++ F TT L+L+ + DF+VV L K G L + L +
Sbjct: 921 LQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANLIKGSS 979
Query: 1092 ADNFANRRMHHLKINREGREL-TIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLD 1150
+ + H++ I+R+ L T+++D ++ + L +G V +
Sbjct: 980 NKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGAR-NLDLKSDLYIGGVAKETYKS 1038
Query: 1151 SEVAKANAMGFAGCMSSVQYNHIAP 1175
GF GC++SV N P
Sbjct: 1039 LPKLVHAKEGFQGCLASVDLNGRLP 1063
Score = 51.2 bits (121), Expect = 6e-06
Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 38/239 (15%)
Query: 368 ITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLL--LSLEGGIL 425
+ F + G + P +SFQ +T + GL+L + EG L + GG L
Sbjct: 31 LEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRL 89
Query: 426 RLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSG 485
+L A +L + +NDG WHSV I + TL +D ++ WV++ S
Sbjct: 90 QLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQ------VEAKWVEVKSK 143
Query: 486 -------NSYYFGGCPDNLTDS------QCLNPIKAFQGCMRLIFIDNQPKDLISVQQGS 532
+ + GG P L + + + F+G +R + +++ ++ V G
Sbjct: 144 RRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNS--SQVLPVDSGE 201
Query: 533 L---------GNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATC 582
+ G S C + C +GG CS C+CS T + G C
Sbjct: 202 VKLDDEPPNSGGGSP-----CEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/163 (22%), Positives = 70/163 (42%), Gaps = 19/163 (11%)
Query: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
ST D +++ F ++Q + VL + G D++ L + +G++ + N+G + S
Sbjct: 1146 STRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES-- 1203
Query: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKHT--QHFRTKGETDALDIDYELSFGGIPV 314
++++D +H V R G VD + + + + + GG
Sbjct: 1204 ----NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-KE 1258
Query: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNV 356
G+P F G + LYYNG+ ++++A I GNV
Sbjct: 1259 QGQP-------FQGQLSGLYYNGLKVLNMAAENDANIAIVGNV 1294
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 127 bits (318), Expect = 9e-29
Identities = 122/457 (26%), Positives = 197/457 (43%), Gaps = 49/457 (10%)
Query: 174 CSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQ-RGDHITLE 232
C ++ V +DG + + +M T + +SL+F+S + G+L + D + LE
Sbjct: 752 CEREATVLSYDGSMFMKIQL-PVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLE 810
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATL--GSLLDDQHWHSVLIERVGKQVNFTVDKHTQ 290
L GR+ L +NL + +SS TL G L+D WH+V + R GK + TVD Q
Sbjct: 811 LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQ-Q 869
Query: 291 HFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQ 350
+ D +++ GI + + + NF G +++L +NG+ IDL K
Sbjct: 870 AMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDID 929
Query: 351 IYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELS 410
N F P+TF S SY+ L + + FQF+T + DGL+L
Sbjct: 930 YCELNARFGFRNIIADPVTFKTKS-SYVALATLQAYTSMHLFFQFKTTSLDGLILYNS-G 987
Query: 411 EGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN---LNDGLWHSVSINARRNRI-TLTL 466
+G+ +++ L G L V A ++ GS+ LND WH+V I+ + + T+ +
Sbjct: 988 DGNDFIVVELVKGYLHYVFD--LGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKI 1045
Query: 467 DDEAAPPAPDSTWVQIYSG-------NSYYFGGCPDNLTDS--QCLNPIKAFQGCMRLIF 517
D + QI +G + Y GG S + ++ + FQGC+ +
Sbjct: 1046 DTKIT--------TQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVD 1097
Query: 518 IDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSY 577
++ + DLIS +L + C + C + G C Q W F C+CS TS+
Sbjct: 1098 LNGRLPDLIS---DALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSF 1154
Query: 578 TGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPL 614
+G C N G YI S G G +
Sbjct: 1155 SGPLC----------------NDPGTTYIFSKGGGQI 1175
Score = 126 bits (316), Expect = 2e-28
Identities = 130/492 (26%), Positives = 220/492 (44%), Gaps = 77/492 (15%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGI-KDFIRLEISSPSEITFA 851
V+F T++SY+ T A S + F FKTT+L G+ L N G DFI +E+ + +
Sbjct: 947 VTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYV 1005
Query: 852 IDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLN 911
D+GNG + S LNDNQWH V R+ + +T+ T+ G L L
Sbjct: 1006 FDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITA--GARNLDLK 1063
Query: 912 SQLFVGGTSSR-----------QKGFLGCIRSLHLNGQKMDLEERAKVTSG-VRPGCPGH 959
S L++GG + ++GF GC+ S+ LNG+ DL A +G + GC G
Sbjct: 1064 SDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGP 1123
Query: 960 CSS-YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMF-----Q 1013
++ C N G C+++ +G+ CDC+ + + GP C + GT TY+F Q
Sbjct: 1124 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN-------DPGT--TYIFSKGGGQ 1174
Query: 1014 EPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSS--QDFVVVLLCKN 1071
Y N S+ A + +A+ F T Q ++L+ ++SSS D+ + L
Sbjct: 1175 ITYKWPPNDRPSTRA---------DRLAIGFSTVQKEAVLVRVDSSSGLGDY-LELHIHQ 1224
Query: 1072 GSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMD-------------- 1117
G + V++++ ++ + +A + + H ++ R G T+Q+D
Sbjct: 1225 GKIGVKFNVGTDDIAIEESNA-IINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND 1283
Query: 1118 -QQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEV-----AKANAMGFAGCMSSVQYN 1171
++L ++ P RV+ L K + +S+ K F G +S + YN
Sbjct: 1284 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYN 1343
Query: 1172 HIAPLK-AALRHATVAPV-------TVHGTLTESSCGFMVDSDVN-----AVTTVHSSSD 1218
+ L AA A +A V V ++T S + S+++ TT+ +S+
Sbjct: 1344 GLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTA 1403
Query: 1219 PFGKTDEREPLT 1230
GK +EP++
Sbjct: 1404 RRGKPPTKEPIS 1415
Score = 115 bits (289), Expect = 2e-25
Identities = 117/460 (25%), Positives = 193/460 (41%), Gaps = 80/460 (17%)
Query: 180 VADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLA 239
+A F G Y +Q + + D I+L FK++Q +G++ H G+ D++ L L+ G ++
Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 374
Query: 240 LHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQ---------------VNFT 284
L +NLG +L G +D WH V + R +Q V +
Sbjct: 375 LVINLGSGAFE---ALVEPVNGKF-NDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430
Query: 285 VDKH-TQHFRTKGETDALDIDYELSFGGIPVPGK-PGTFLKKNFHGCIENLYYNGVNI-I 341
VD T T+ + L D GG P PG+ + NF GC++ + Y ++ +
Sbjct: 431 VDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRL 490
Query: 342 DLAKRRKH-----QIYTGNVTFSCSEPQIV-PITFVNSSGSYLLLPGTPQIDGLSVSFQF 395
+L++ K +I+ G V F C + PITF + S++ LP S+SF F
Sbjct: 491 ELSRLAKQGDPKMKIH-GVVAFKCENVATLDPITF-ETPESFISLPKWNAKKTGSISFDF 548
Query: 396 RTWNKDGLLL-----------------------STELSEGSGTLLLSLEGGILRLVIQKM 432
RT +GL+L + E+ +G LLL + G ++ I+ +
Sbjct: 549 RTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIK--IKAL 606
Query: 433 TERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGG 492
++V NDG W+ V T++++ P + + Y GG
Sbjct: 607 LKKV---------NDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGG 657
Query: 493 CPDNLTD--------SQCLNPIKAFQGCMRLIFIDNQPKDL--ISVQQGSLGNFSDLHID 542
P+N + LN + GC+R +FID Q KD+ ++ Q + G +
Sbjct: 658 LPENKAGLVFPTEVWTALLN--YGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKE 715
Query: 543 LCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATC 582
CL N C++ G C W + C+CS T Y G +C
Sbjct: 716 TAK---PCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 752
Score = 109 bits (273), Expect = 2e-23
Identities = 97/416 (23%), Positives = 187/416 (44%), Gaps = 53/416 (12%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLG-------------IK-DFI 838
++F T S++ P ++A+ + ISF F+TT +G+ L + G IK DF
Sbjct: 522 ITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFF 581
Query: 839 RLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTR 898
+E+ + +D+G+G +++ + ND +W++V +R+ + ++ V+ L T
Sbjct: 582 AIEMLD-GHLYLLLDMGSGTIKIKALLKKV-NDGEWYHVDFQRDGRSGTISVNTL--RTP 637
Query: 899 ETSEEGHFRLQLNSQLFVGG---------------TSSRQKGFLGCIRSLHLNGQKMDLE 943
T+ L L+ +L++GG T+ G++GCIR L ++GQ D+
Sbjct: 638 YTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIR 697
Query: 944 ERAKV--TSGVRPGCPGHCSS--YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVS 999
+ A+V T+GV+P C + + C N G C + N Y+CDC+ + Y G C++E +
Sbjct: 698 QMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREAT 757
Query: 1000 AVFEAGTSVTYMFQE-PYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINS 1058
+ G+ MF + PV + ++ S + + + A +L L +++
Sbjct: 758 VLSYDGS----MFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDA 813
Query: 1059 SSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQ 1118
V L C +R + N + N + H +++ R G+ L + +D
Sbjct: 814 GRVKLTVNLDC------IRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDD 867
Query: 1119 QLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIA 1174
Q ++ + + ++ G +TE L S + F G + S+ +N +A
Sbjct: 868 QQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPS-----NFIGHLQSLTFNGMA 918
Score = 71.6 bits (174), Expect = 5e-12
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 28/226 (12%)
Query: 798 EASYLHFPTFHAEFSADISFFFKTTALSGVFL--ENLGIKDFIRLEISSPSEITFAIDVG 855
E + FP ++A +++SF KT + G+ L ++ G DF+ L ++ + + +
Sbjct: 37 EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96
Query: 856 NG-PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQL 914
P L+ +P +ND WH VR R + T+L +D + E + + + S L
Sbjct: 97 CAEPATLLADTP--VNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGL 153
Query: 915 FVGG---------------TSSRQKGFLGCIRSLHLNGQKMDLEERAKV-------TSGV 952
FVGG + ++ F G IR + +N ++ + +V SG
Sbjct: 154 FVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGG 213
Query: 953 RPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEV 998
C G +C NGG C + +CDC+ + + G C +E+
Sbjct: 214 GSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259
Score = 52.4 bits (124), Expect = 3e-06
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 38/243 (15%)
Query: 368 ITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLL--LSLEGGIL 425
+ F + G + P +SFQ +T + GL+L + EG L + GG L
Sbjct: 31 LEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRL 89
Query: 426 RLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSG 485
+L A +L + +NDG WHSV I + TL +D ++ WV++ S
Sbjct: 90 QLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQ------VEAKWVEVKSK 143
Query: 486 -------NSYYFGGCPDNLTDS------QCLNPIKAFQGCMRLIFIDNQPKDLISVQQGS 532
+ + GG P L + + + F+G +R + +++ ++ V G
Sbjct: 144 RRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNS--SQVLPVDSGE 201
Query: 533 L---------GNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCH 583
+ G S C + C +GG CS C+CS T + G C
Sbjct: 202 VKLDDEPPNSGGGSP-----CEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS 256
Query: 584 NSI 586
I
Sbjct: 257 QEI 259
Score = 52.4 bits (124), Expect = 3e-06
Identities = 86/385 (22%), Positives = 145/385 (37%), Gaps = 74/385 (19%)
Query: 808 HAEFSADISFFFKTTALSGVFLENLG--IKDFIRLEISSPS-EITFAIDV-------GNG 857
H E + D+S F++ G+ + D +RLE+ + ++T +D G
Sbjct: 776 HTE-AEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKG 834
Query: 858 PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917
P L LNDN+WH VR R K L VD+ T + + + H RL+ ++ + G
Sbjct: 835 PETLFAGYN--LNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN-IETG 890
Query: 918 GTSSRQ------KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGG 971
+ R+ F+G ++SL NG +Y +C NG
Sbjct: 891 IITERRYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNG- 926
Query: 972 KCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYT 1031
+ +C E++A F + PVT S A+ T
Sbjct: 927 ------------------DIDYC--ELNARFGFRNIIAD------PVTFKTKSSYVALAT 960
Query: 1032 DSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTID 1091
A + ++ F TT L+L+ + DF+VV L K G L + L +
Sbjct: 961 LQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANLIKGSS 1019
Query: 1092 ADNFANRRMHHLKINREGREL-TIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLD 1150
+ + H++ I+R+ L T+++D ++ + L +G V +
Sbjct: 1020 NKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGAR-NLDLKSDLYIGGVAKETYKS 1078
Query: 1151 SEVAKANAMGFAGCMSSVQYNHIAP 1175
GF GC++SV N P
Sbjct: 1079 LPKLVHAKEGFQGCLASVDLNGRLP 1103
Score = 50.4 bits (119), Expect = 1e-05
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 26/156 (16%)
Query: 812 SADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPS-LLN 870
S +I+ FKT +G+ L D++ L + + + ++ I++G+G E +V+ + N
Sbjct: 338 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKFN 396
Query: 871 DNQWHYVRAERNLKETS---------------LQVDNLPRSTRETSEEGHFRLQLNSQLF 915
DN WH V+ RNL++ S + VD + +T T E+ + L + +
Sbjct: 397 DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQED-YTMLGSDDFFY 455
Query: 916 VGGTSSR--------QKGFLGCIRSLHLNGQKMDLE 943
VGG+ S F+GC++ + + LE
Sbjct: 456 VGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLE 491
Score = 36.6 bits (83), Expect = 0.16
Identities = 43/188 (22%), Positives = 72/188 (38%), Gaps = 39/188 (20%)
Query: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
ST D +++ F ++Q + VL + G D++ L + +G++ + N+G + S
Sbjct: 1186 STRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES-- 1243
Query: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFR-TKGETD-------ALDIDYEL- 307
++++D +H V R G VD R G D I Y L
Sbjct: 1244 ----NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLG 1299
Query: 308 ------------------SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKH 349
S I + GK + F G + LYYNG+ ++++A
Sbjct: 1300 RVVDEWLLDKGRQLTIFNSQATIIIGGKE---QGQPFQGQLSGLYYNGLKVLNMAAENDA 1356
Query: 350 QI-YTGNV 356
I GNV
Sbjct: 1357 NIAIVGNV 1364
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 120 bits (300), Expect = 1e-26
Identities = 129/489 (26%), Positives = 210/489 (42%), Gaps = 64/489 (13%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGI-KDFIRLEISSPSEITFA 851
V+F + +SYL T A S + F FKTTA G+ L N G DFI +E+ I +
Sbjct: 920 VTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVK-GYIHYV 978
Query: 852 IDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKET-SLQVDNLPRSTRETSEEGHFRLQL 910
D+GNGP + S +NDNQWH V R+ +L++D+ T G L L
Sbjct: 979 FDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDL 1035
Query: 911 NSQLFVGGTSSR-----------QKGFLGCIRSLHLNGQKMDLEERAKVTSG-VRPGCPG 958
+L++GG S + GF GC+ S+ LNG+ DL A G V GC G
Sbjct: 1036 KGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDG 1095
Query: 959 HCSSYGS-ICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYP 1017
++ C N G C+++ +G+ CDCT + Y GP C + GT TY+F
Sbjct: 1096 PSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGT--TYIF----- 1141
Query: 1018 VTKNISLSSSAIYTDSAPS--KENIALSFVTTQAPSLLLFINSSS--QDFVVVLLCKNGS 1073
K +L + + PS + +A+ F T Q ++L+ ++S+S D+ + L G+
Sbjct: 1142 -GKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDY-LQLHIDQGT 1199
Query: 1074 LQVRYHLNKEETHVFTIDADN--FANRRMHHLKINREGRELTIQMD-------------- 1117
+ V +++ ++ TID N ++ + H ++ R G T+Q+D
Sbjct: 1200 VGVIFNVGTDD---ITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD 1256
Query: 1118 -QQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVA-----KANAMGFAGCMSSVQYN 1171
++L ++ P RV+ L K + +S+ A + F G +S + YN
Sbjct: 1257 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYN 1316
Query: 1172 HIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTN 1231
+ L A H L ++ ++ A T + + +T T
Sbjct: 1317 GLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTT 1376
Query: 1232 AVRSDSAVI 1240
R S +
Sbjct: 1377 TRRGRSPTL 1385
Score = 112 bits (281), Expect = 2e-24
Identities = 104/420 (24%), Positives = 175/420 (41%), Gaps = 20/420 (4%)
Query: 174 CSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRG-DHITLE 232
C ++ V +DG + + + +DV SL+F S + G++ + D + LE
Sbjct: 726 CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATL--GSLLDDQHWHSVLIERVGKQVNFTVDKHTQ 290
L G++ L +NL + + S TL G L+D WH+V + R GK + +VD T
Sbjct: 785 LDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTV 844
Query: 291 HFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQ 350
+ G + +++ GI + + + NF G + L +NG +D K
Sbjct: 845 EGQMAGAH--MRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDIT 902
Query: 351 IYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELS 410
N F P+TF S SYL L + + FQF+T DGLLL
Sbjct: 903 YCELNARFGLRAIVADPVTF-KSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS-G 960
Query: 411 EGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN---LNDGLWHSVSINARRNRI-TLTL 466
G+ +++ L G + V ++ G++ +ND WH+V ++ + TL +
Sbjct: 961 NGNDFIVIELVKGYIHYVFD--LGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKI 1018
Query: 467 DDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDS--QCLNPIKAFQGCMRLIFIDNQPKD 524
D + G Y GG N+ + + + FQGC+ + ++ + D
Sbjct: 1019 DSRTVTQHSNGARNLDLKGE-LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPD 1077
Query: 525 LISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHN 584
LI+ +L + C C + G C Q W F C+C+ TSY G C++
Sbjct: 1078 LIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCND 1134
Score = 110 bits (275), Expect = 9e-24
Identities = 114/451 (25%), Positives = 196/451 (43%), Gaps = 61/451 (13%)
Query: 180 VADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLA 239
VA F G Y + + + D I+L F+++Q +G++ H G+ D++ L L+ G +
Sbjct: 289 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 347
Query: 240 LHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQ---------------VNFT 284
L +NLG +L G +D WH V + R +Q V +
Sbjct: 348 LVINLGSGAFE---ALVEPVNGKF-NDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTIS 403
Query: 285 VDKH-TQHFRTKGETDALDIDYELSFGGIP-VPGKPGTFLKKNFHGCIENLYYNG----V 338
VD T T+ + L D GG P PG+ + NF GC++++ Y +
Sbjct: 404 VDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKL 463
Query: 339 NIIDLAKRRKHQI-YTGNVTFSCSEPQIV-PITFVNSSGSYLLLPGTPQIDGLSVSFQFR 396
+ LAK ++ G+++F C + + P+TF S +++ LP S+S FR
Sbjct: 464 ELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTF-ESPEAFVALPRWSAKRTGSISLDFR 522
Query: 397 TWNKDGLLLSTE---LSEGSGT---------LLLSLEGGILRLVIQKMTERVAEILTGSN 444
T +GLLL ++ G+G+ + L G L L++ + + +
Sbjct: 523 TTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRK 582
Query: 445 LNDGLWHSVSINARRNRITLTLDDEAAP--PAPDSTWVQIYSGNSYYFGGCPDNLTDSQC 502
+NDG W V + +++++ + P DS + + S Y GG P+
Sbjct: 583 VNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLES--ELYLGGLPEGGRVDLP 640
Query: 503 LNP------IKA-FQGCMRLIFIDNQPKDL--ISVQQGSLGNFSDLHIDLCSIKD--RCL 551
L P ++A + GC+R +FID + +DL ++ QG++G CS + +C
Sbjct: 641 LPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV-----APFCSRETLKQCA 695
Query: 552 PNYCEHGGSCSQSWTTFYCNCSDTSYTGATC 582
C +GG C + W F C+C T + G C
Sbjct: 696 SAPCRNGGVCREGWNRFICDCIGTGFLGRVC 726
Score = 92.0 bits (227), Expect = 3e-18
Identities = 84/370 (22%), Positives = 171/370 (46%), Gaps = 69/370 (18%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIK--------------DFI 838
V+F + +++ P + A+ + IS F+TT +G+ L + G + D+
Sbjct: 495 VTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYF 554
Query: 839 RLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTR 898
+E+ + +D+G+G ++L S + ND +W +V +R+ ++ S+ V++ RST
Sbjct: 555 AMELLD-GHLYLLLDMGSGGIKLRASSRKV-NDGEWCHVDFQRDGRKGSISVNS--RSTP 610
Query: 899 ETSEEGHFRLQLNSQLFVGG----------------TSSRQKGFLGCIRSLHLNGQKMDL 942
+ L L S+L++GG T++ + G++GC+R L ++G+ DL
Sbjct: 611 FLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDL 670
Query: 943 EERAKVTS--GVRPGCPGH----CSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKK 996
A+ GV P C C+S + C NGG C E N ++CDC + + G C++
Sbjct: 671 RGLAEAQGAVGVAPFCSRETLKQCAS--APCRNGGVCREGWNRFICDCIGTGFLGRVCER 728
Query: 997 EVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFI 1056
E + + G+ M+ + + +A++T++ E+++L F++ +A L++
Sbjct: 729 EATVLSYDGS----MYMK--------IMLPNAMHTEA----EDVSLRFMSQRAYGLMMAT 772
Query: 1057 NSSSQDFVVVLLCKNGSLQVRYHL---------NKEETHVFTIDADNFANRRMHHLKINR 1107
S + L G +++ +L +K +F + H +++ R
Sbjct: 773 TSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFA--GHKLNDNEWHTVRVVR 830
Query: 1108 EGRELTIQMD 1117
G+ L + +D
Sbjct: 831 RGKSLQLSVD 840
Score = 57.0 bits (136), Expect = 1e-07
Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 27/207 (13%)
Query: 809 AEFSADISFFFKTTALSGV--FLENLGIKDFIRLE-ISSPSEITFAIDVGNGPVELVVQS 865
A S ++SF +T A + +L++ G DF+ L + + F + P L + +
Sbjct: 47 AASSGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE-PATLQLDT 105
Query: 866 PSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGG------- 918
P + D++WH V R+ + T+L VD R+ S+ +Q+ S LFVGG
Sbjct: 106 P--VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRR--EMQVASDLFVGGIPPDVRL 161
Query: 919 ------TSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGH-CSSYGSICHNGG 971
T + F G + +L L + L + G+R C+ + C NGG
Sbjct: 162 SALTLSTVKYEPPFRGLLANLKLGERPPAL----LGSQGLRGATADPLCAPARNPCANGG 217
Query: 972 KCVEKHNGYL-CDCTNSPYEGPFCKKE 997
C G + CDC+++ + G FC +E
Sbjct: 218 LCTVLAPGEVGCDCSHTGFGGKFCSEE 244
Score = 52.8 bits (125), Expect = 2e-06
Identities = 92/387 (23%), Positives = 154/387 (39%), Gaps = 79/387 (20%)
Query: 808 HAEFSADISFFFKTTALSGVFLENLGIK--DFIRLEISSPS-EITFAIDV-------GNG 857
H E + D+S F + G+ + + D +RLE+ ++T +D G
Sbjct: 750 HTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKG 808
Query: 858 PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEG-HFRLQLNSQLFV 916
P L LNDN+WH VR R K L VDN+ T E G H RL+ ++ +
Sbjct: 809 PETLFAGHK--LNDNEWHTVRVVRRGKSLQLSVDNV---TVEGQMAGAHMRLEFHN-IET 862
Query: 917 GGTSSRQ------KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNG 970
G + R+ F+G + L NGQ Y C +G
Sbjct: 863 GIMTERRFISVVPSNFIGHLSGLVFNGQP-----------------------YMDQCKDG 899
Query: 971 GKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIY 1030
D T +C E++A F V PVT S A+
Sbjct: 900 ------------DIT-------YC--ELNARFGLRAIVAD------PVTFKSRSSYLALA 932
Query: 1031 TDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTI 1090
T A + ++ F TT LLLF + + DF+V+ L K G + + L + +
Sbjct: 933 TLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVK-GYIHYVFDLGNGPSLMKGN 991
Query: 1091 DADNFANRRMHHLKINRE-GRELTIQMDQQLRLSY-NFSPEVEFRVIRSLTLGKVTENLG 1148
+ + H++ ++R+ G T+++D + + N + ++ + L +G +++N+
Sbjct: 992 SDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLK--GELYIGGLSKNMF 1049
Query: 1149 LDSEVAKANAMGFAGCMSSVQYNHIAP 1175
+ A+ GF GC++SV N P
Sbjct: 1050 SNLPKLVASRDGFQGCLASVDLNGRLP 1076
Score = 49.3 bits (116), Expect = 2e-05
Identities = 40/160 (25%), Positives = 74/160 (46%), Gaps = 28/160 (17%)
Query: 814 DISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPS-LLNDN 872
+I+ F+T +G+ L D++ L + S + + I++G+G E +V+ + NDN
Sbjct: 313 EITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFNDN 371
Query: 873 QWHYVRAERNLKE---------------TSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917
WH VR RNL++ ++ VD + +T T E+ + L + ++G
Sbjct: 372 AWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQED-YTMLGSDDFFYIG 430
Query: 918 GT--------SSRQKGFLGCIRSL--HLNGQKMDLEERAK 947
G+ S F+GC++ + N K++L AK
Sbjct: 431 GSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAK 470
Score = 48.1 bits (113), Expect = 5e-05
Identities = 57/237 (24%), Positives = 88/237 (37%), Gaps = 17/237 (7%)
Query: 391 VSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLW 450
+SF RT LLL + L L L G LRL A + + + D W
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112
Query: 451 HSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGC-PDNLTDSQCLNPIK-- 507
H V + R L +D EA S ++ + + GG PD + L+ +K
Sbjct: 113 HMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYE 172
Query: 508 -AFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLP--NYCEHGGSCS-Q 563
F+G + + + +P L+ QG G +D C P N C +GG C+
Sbjct: 173 PPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLCTVL 222
Query: 564 SWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVY 620
+ C+CS T + G C + + + G G+G G V+
Sbjct: 223 APGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVH 279
Score = 37.7 bits (86), Expect = 0.073
Identities = 34/157 (21%), Positives = 63/157 (40%), Gaps = 9/157 (5%)
Query: 159 WNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVL 218
W P+ + + + + ++D +F G R+ + + +S ++ +L
Sbjct: 7 WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66
Query: 219 FH-GEGQRGDHITLELQKGRLALHLNLGDSK-ARLSSSLPSATLGSLLDDQHWHSVLIER 276
+ +G D + L L GRL L L ++ A L P A D WH VL+ R
Sbjct: 67 LYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVA-------DDRWHMVLLTR 119
Query: 277 VGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIP 313
++ VD + + + + + +L GGIP
Sbjct: 120 DARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIP 156
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 119 bits (298), Expect = 2e-26
Identities = 106/346 (30%), Positives = 167/346 (48%), Gaps = 44/346 (12%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGI-KDFIRLEISSPSEITFA 851
V+F + +SYL T A S + F FKTTA G+ L N G DFI +E+ I +
Sbjct: 880 VTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVK-GYIHYV 938
Query: 852 IDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKET-SLQVDNLPRSTRETSEEGHFRLQL 910
D+GNGP + S +NDNQWH V R+ +L++D+ T G L L
Sbjct: 939 FDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDL 995
Query: 911 NSQLFVGGTSSR-----------QKGFLGCIRSLHLNGQKMDLEERAKVTSG-VRPGCPG 958
+L++GG S + GF GC+ S+ LNG+ DL A G V GC G
Sbjct: 996 KGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDG 1055
Query: 959 HCSSYGS-ICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYP 1017
++ C N G C+++ +G+ CDCT + Y GP C + GT TY+F
Sbjct: 1056 PSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN-------DPGT--TYIF----- 1101
Query: 1018 VTKNISLSSSAIYTDSAPS--KENIALSFVTTQAPSLLLFINSSS--QDFVVVLLCKNGS 1073
K +L + + PS + +A+ F T Q ++L+ ++S+S D+ + L G+
Sbjct: 1102 -GKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDY-LQLHIDQGT 1159
Query: 1074 LQVRYHLNKEETHVFTIDADN--FANRRMHHLKINREGRELTIQMD 1117
+ V +++ ++ TID N ++ + H ++ R G T+Q+D
Sbjct: 1160 VGVIFNVGTDD---ITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202
Score = 113 bits (282), Expect = 1e-24
Identities = 114/444 (25%), Positives = 196/444 (44%), Gaps = 54/444 (12%)
Query: 180 VADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLA 239
VA F G Y + + + D I+L F+++Q +G++ H G+ D++ L L+ G +
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 323
Query: 240 LHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQ--------VNFTVDKH-TQ 290
L +NLG +L G +D WH V + R +Q V +VD T
Sbjct: 324 LVINLGSGAFE---ALVEPVNGKF-NDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT 379
Query: 291 HFRTKGETDALDIDYELSFGGIP-VPGKPGTFLKKNFHGCIENLYYNG----VNIIDLAK 345
T+ + L D GG P PG+ + NF GC++++ Y + + LAK
Sbjct: 380 TGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAK 439
Query: 346 RRKHQI-YTGNVTFSCSEPQIV-PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGL 403
++ G+++F C + + P+TF S +++ LP S+S FRT +GL
Sbjct: 440 EGDPKMKLQGDLSFRCEDVAALDPVTF-ESPEAFVALPRWSAKRTGSISLDFRTTEPNGL 498
Query: 404 LLSTE---LSEGSGT---------LLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWH 451
LL ++ G+G+ + L G L L++ + + + +NDG W
Sbjct: 499 LLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWC 558
Query: 452 SVSINARRNRITLTLDDEAAP--PAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNP---- 505
V + +++++ + P DS + + S Y GG P+ L P
Sbjct: 559 HVDFQRDGRKGSISVNSRSTPFLATGDSEILDLES--ELYLGGLPEGGRVDLPLPPEVWT 616
Query: 506 --IKA-FQGCMRLIFIDNQPKDL--ISVQQGSLGNFSDLHIDLCSIKD--RCLPNYCEHG 558
++A + GC+R +FID + +DL ++ QG++G CS + +C C +G
Sbjct: 617 AALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV-----APFCSRETLKQCASAPCRNG 671
Query: 559 GSCSQSWTTFYCNCSDTSYTGATC 582
G C + W F C+C T + G C
Sbjct: 672 GVCREGWNRFICDCIGTGFLGRVC 695
Score = 112 bits (281), Expect = 2e-24
Identities = 103/418 (24%), Positives = 173/418 (41%), Gaps = 25/418 (5%)
Query: 174 CSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRG-DHITLE 232
C ++ V +DG + + + +DV SL+F S + G++ + D + LE
Sbjct: 695 CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHF 292
L G++ L +NLG L + G L+D WH+V + R GK + +VD T
Sbjct: 754 LDGGQMKLTVNLGKGPETLFA-------GHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806
Query: 293 RTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIY 352
+ G + +++ GI + + + NF G + L +NG +D K
Sbjct: 807 QMAGAH--MRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYC 864
Query: 353 TGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEG 412
N F P+TF S SYL L + + FQF+T DGLLL G
Sbjct: 865 ELNARFGLRAIVADPVTF-KSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS-GNG 922
Query: 413 SGTLLLSLEGGILRLVIQKMTERVAEILTGSN---LNDGLWHSVSINARRNRI-TLTLDD 468
+ +++ L G + V ++ G++ +ND WH+V ++ + TL +D
Sbjct: 923 NDFIVIELVKGYIHYVFD--LGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS 980
Query: 469 EAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDS--QCLNPIKAFQGCMRLIFIDNQPKDLI 526
+ G Y GG N+ + + + FQGC+ + ++ + DLI
Sbjct: 981 RTVTQHSNGARNLDLKGE-LYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLI 1039
Query: 527 SVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHN 584
+ +L + C C + G C Q W F C+C+ TSY G C++
Sbjct: 1040 A---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCND 1094
Score = 99.4 bits (246), Expect = 2e-20
Identities = 84/361 (23%), Positives = 170/361 (47%), Gaps = 60/361 (16%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIK--------------DFI 838
V+F + +++ P + A+ + IS F+TT +G+ L + G + D+
Sbjct: 464 VTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYF 523
Query: 839 RLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTR 898
+E+ + +D+G+G ++L S + ND +W +V +R+ ++ S+ V++ RST
Sbjct: 524 AMELLD-GHLYLLLDMGSGGIKLRASSRKV-NDGEWCHVDFQRDGRKGSISVNS--RSTP 579
Query: 899 ETSEEGHFRLQLNSQLFVGG----------------TSSRQKGFLGCIRSLHLNGQKMDL 942
+ L L S+L++GG T++ + G++GC+R L ++G+ DL
Sbjct: 580 FLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDL 639
Query: 943 EERAKVTS--GVRPGCPGH----CSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKK 996
A+ GV P C C+S + C NGG C E N ++CDC + + G C++
Sbjct: 640 RGLAEAQGAVGVAPFCSRETLKQCAS--APCRNGGVCREGWNRFICDCIGTGFLGRVCER 697
Query: 997 EVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFI 1056
E + + G+ M+ + + +A++T++ E+++L F++ +A L++
Sbjct: 698 EATVLSYDGS----MYMK--------IMLPNAMHTEA----EDVSLRFMSQRAYGLMMAT 741
Query: 1057 NSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQM 1116
S + L G +++ +L K +F + H +++ R G+ L + +
Sbjct: 742 TSRESADTLRLELDGGQMKLTVNLGKGPETLFA--GHKLNDNEWHTVRVVRRGKSLQLSV 799
Query: 1117 D 1117
D
Sbjct: 800 D 800
Score = 60.8 bits (146), Expect = 8e-09
Identities = 91/379 (24%), Positives = 155/379 (40%), Gaps = 72/379 (18%)
Query: 808 HAEFSADISFFFKTTALSGVFLENLGIK--DFIRLEISSPSEITFAIDVGNGPVELVVQS 865
H E + D+S F + G+ + + D +RLE+ ++ +++G GP L
Sbjct: 719 HTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDG-GQMKLTVNLGKGPETLFAGH 776
Query: 866 PSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEG-HFRLQLNSQLFVGGTSSRQ- 923
LNDN+WH VR R K L VDN+ T E G H RL+ ++ + G + R+
Sbjct: 777 K--LNDNEWHTVRVVRRGKSLQLSVDNV---TVEGQMAGAHMRLEFHN-IETGIMTERRF 830
Query: 924 -----KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHN 978
F+G + L NGQ Y C +G
Sbjct: 831 ISVVPSNFIGHLSGLVFNGQ-----------------------PYMDQCKDG-------- 859
Query: 979 GYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKE 1038
D T +C E++A F V PVT S A+ T A +
Sbjct: 860 ----DIT-------YC--ELNARFGLRAIVA------DPVTFKSRSSYLALATLQAYASM 900
Query: 1039 NIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANR 1098
++ F TT LLLF + + DF+V+ L K G + + L + + +
Sbjct: 901 HLFFQFKTTAPDGLLLFNSGNGNDFIVIELVK-GYIHYVFDLGNGPSLMKGNSDKPVNDN 959
Query: 1099 RMHHLKINRE-GRELTIQMDQQLRLSY-NFSPEVEFRVIRSLTLGKVTENLGLDSEVAKA 1156
+ H++ ++R+ G T+++D + + N + ++ + L +G +++N+ + A
Sbjct: 960 QWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLK--GELYIGGLSKNMFSNLPKLVA 1017
Query: 1157 NAMGFAGCMSSVQYNHIAP 1175
+ GF GC++SV N P
Sbjct: 1018 SRDGFQGCLASVDLNGRLP 1036
Score = 60.1 bits (144), Expect = 1e-08
Identities = 78/325 (24%), Positives = 138/325 (42%), Gaps = 33/325 (10%)
Query: 809 AEFSADISFFFKTTALSGV--FLENLGIKDFIRLE-ISSPSEITFAIDVGNGPVELVVQS 865
A S ++SF +T A + +L++ G DF+ L + + F + P L + +
Sbjct: 47 AASSGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE-PATLQLDT 105
Query: 866 PSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGG------- 918
P + D++WH V R+ + T+L VD R+ S+ +Q+ S LFVGG
Sbjct: 106 P--VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRR--EMQVASDLFVGGIPPDVRL 161
Query: 919 ------TSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGH-CSSYGSICHNGG 971
T + F G + +L L + L + G+R C+ + C NGG
Sbjct: 162 SALTLSTVKYEPPFRGLLANLKLGERPPAL----LGSQGLRGATADPLCAPARNPCANGG 217
Query: 972 KCVEKHNGYL-CDCTNSPYEGPFCKKEVSAV-FEAGTSVTYMFQEPYPVT--KNISLSSS 1027
C G + CDC+++ + G FC +E + A ++ +E + T N
Sbjct: 218 LCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYD 277
Query: 1028 AIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHV 1087
+ S + I L+F T Q L+L S+ D+V + L K+G++ + +L
Sbjct: 278 LSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSA-DYVNLSL-KSGAVWLVINLGSGAFEA 335
Query: 1088 FTIDAD-NFANRRMHHLKINREGRE 1111
+ F + H +++ R R+
Sbjct: 336 LVEPVNGKFNDNAWHDVRVTRNLRQ 360
Score = 52.0 bits (123), Expect = 4e-06
Identities = 40/153 (26%), Positives = 74/153 (48%), Gaps = 21/153 (13%)
Query: 814 DISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPS-LLNDN 872
+I+ F+T +G+ L D++ L + S + + I++G+G E +V+ + NDN
Sbjct: 289 EITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFNDN 347
Query: 873 QWHYVRAERNLKE--------TSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGT----- 919
WH VR RNL++ ++ VD + +T T E+ + L + ++GG+
Sbjct: 348 AWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYIGGSPNTAD 406
Query: 920 ---SSRQKGFLGCIRSL--HLNGQKMDLEERAK 947
S F+GC++ + N K++L AK
Sbjct: 407 LPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAK 439
Score = 46.2 bits (108), Expect = 2e-04
Identities = 52/199 (26%), Positives = 78/199 (39%), Gaps = 17/199 (8%)
Query: 391 VSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLW 450
+SF RT LLL + L L L G LRL A + + + D W
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112
Query: 451 HSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGC-PDNLTDSQCLNPIK-- 507
H V + R L +D EA S ++ + + GG PD + L+ +K
Sbjct: 113 HMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYE 172
Query: 508 -AFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLP--NYCEHGGSCS-Q 563
F+G + + + +P L+ QG G +D C P N C +GG C+
Sbjct: 173 PPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLCTVL 222
Query: 564 SWTTFYCNCSDTSYTGATC 582
+ C+CS T + G C
Sbjct: 223 APGEVGCDCSHTGFGGKFC 241
Score = 39.3 bits (90), Expect = 0.025
Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
ST D +++ F + Q VL + G D++ L + +G + + N+G + P
Sbjct: 1119 STRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDE--P 1176
Query: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKH--TQHFRTKGETDALDIDYELSFGGIPV 314
+A ++ D +H V R G VD + + + + + GG
Sbjct: 1177 NA----IVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQLTIFNSQAAIKIGGRD- 1231
Query: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT 353
G+P F G + LYYNG+ ++ LA + T
Sbjct: 1232 QGRP-------FQGQVSGLYYNGLKVLALAAESDPNVRT 1263
Score = 37.7 bits (86), Expect = 0.073
Identities = 34/157 (21%), Positives = 63/157 (40%), Gaps = 9/157 (5%)
Query: 159 WNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVL 218
W P+ + + + + ++D +F G R+ + + +S ++ +L
Sbjct: 7 WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66
Query: 219 FH-GEGQRGDHITLELQKGRLALHLNLGDSK-ARLSSSLPSATLGSLLDDQHWHSVLIER 276
+ +G D + L L GRL L L ++ A L P A D WH VL+ R
Sbjct: 67 LYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVA-------DDRWHMVLLTR 119
Query: 277 VGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIP 313
++ VD + + + + + +L GGIP
Sbjct: 120 DARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIP 156
Score = 37.0 bits (84), Expect = 0.12
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 833 GIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPS-LLNDNQWHYVRAERNLKETSLQVD 891
G+ D+++L I T + G ++ + P+ +++D ++H VR R+ +LQVD
Sbjct: 1146 GLGDYLQLHIDQG---TVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202
Query: 892 NLPRSTRETSEEGHFRLQLNSQLFVG-GTSSRQKGFLGCIRSLHLNGQKM 940
+ P E G NSQ + G + + F G + L+ NG K+
Sbjct: 1203 SWP--VNERYPAGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKV 1250
>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
Length = 1061
Score = 117 bits (293), Expect = 7e-26
Identities = 109/421 (25%), Positives = 179/421 (42%), Gaps = 22/421 (5%)
Query: 174 CSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQ-RGDHITLE 232
C ++ + +DG S + +M T + +S +F S + G+L + D + LE
Sbjct: 306 CEREASILSYDG-SMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLE 364
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATL--GSLLDDQHWHSVLIERVGKQVNFTVDKHTQ 290
L GR+ L +NL + +SS TL G L+D WH+V + R GK + TVD
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424
Query: 291 HFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQ 350
G D +++ GI + + + +F G +++L +NG+ IDL K
Sbjct: 425 EGTMVG--DHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDID 482
Query: 351 IYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELS 410
F P+TF S SYL L + + FQF+T + DG +L
Sbjct: 483 YCELKARFGLRNIIADPVTFKTKS-SYLSLATLQAYTSMHLFFQFKTTSPDGFILFNS-G 540
Query: 411 EGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN---LNDGLWHSVSINA-RRNRITLTL 466
+G+ + + L G + V ++ G++ LND WH+V I N +L +
Sbjct: 541 DGNDFIAVELVKGYIHYVFD--LGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKV 598
Query: 467 DDEAAPPAPDSTWVQIYSGNSYYFG---GCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPK 523
D + + G+ Y G G NL + + FQGC+ + ++ +
Sbjct: 599 DTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLP--KLVASRDGFQGCLASVDLNGRLP 656
Query: 524 DLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCH 583
DLI+ +L + C + C + G C Q W F C+CS TSY+G C+
Sbjct: 657 DLIN---DALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN 713
Query: 584 N 584
+
Sbjct: 714 D 714
Score = 109 bits (273), Expect = 2e-23
Identities = 109/406 (26%), Positives = 178/406 (43%), Gaps = 50/406 (12%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGI-KDFIRLEISSPSEITFA 851
V+F T++SYL T A S + F FKTT+ G L N G DFI +E+ I +
Sbjct: 500 VTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVK-GYIHYV 558
Query: 852 IDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKET-SLQVDNLPRSTRETSE--EGHFRL 908
D+GNGP + S LNDNQWH V R+ T SL+VD T+ ++ G L
Sbjct: 559 FDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD-----TKVVTQVINGAKNL 613
Query: 909 QLNSQLFVGGTS-----------SRQKGFLGCIRSLHLNGQKMDLEERAKVTSG-VRPGC 956
L L++ G + + + GF GC+ S+ LNG+ DL A SG + GC
Sbjct: 614 DLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGC 673
Query: 957 PGHCSS-YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEP 1015
G ++ C N G C+++ G+ CDC+ + Y G C TY+F +
Sbjct: 674 EGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN---------DPGATYIFGK- 723
Query: 1016 YPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSS--QDFVVVLLCKNGS 1073
+ + L + + + +A+ F TT +L+ I+S+ DF + L + G
Sbjct: 724 ---SGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDF-LQLHIEQGK 779
Query: 1074 LQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFR 1133
+ V +++ + + + + + H ++ R G T+Q+D N+ +
Sbjct: 780 IGVVFNIGTVDISI-KEERTPVNDGKYHVVRFTRNGGNATLQVD-------NWPVNEHYP 831
Query: 1134 VIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAA 1179
R LT+ + + K F G +S + Y+ + L A
Sbjct: 832 TGRQLTIFNTQAQIAIG---GKDKGRLFQGQLSGLYYDGLKVLNMA 874
Score = 89.4 bits (220), Expect = 2e-17
Identities = 79/370 (21%), Positives = 161/370 (43%), Gaps = 64/370 (17%)
Query: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIK--------------DFI 838
++F T +Y+ P ++ + ISF F+TT +G+ L G DF
Sbjct: 76 INFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFF 135
Query: 839 RLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTR 898
+E+ + +D+G+G ++ V + ND +W++V +R+ + ++ V++ R T
Sbjct: 136 AVELLD-GNLYLLLDMGSGTIK-VKATQKKANDGEWYHVDIQRDGRSGTISVNS--RRTP 191
Query: 899 ETSEEGHFRLQLNSQLFVGG---------------TSSRQKGFLGCIRSLHLNGQKMDLE 943
T+ L L +++GG T+ G++GCIR L ++G+ ++
Sbjct: 192 FTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIR 251
Query: 944 ERAKV--TSGVRPGCPG----HCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKE 997
+ A++ +GV+ C C SY C N C + N ++CDCT + Y G C++E
Sbjct: 252 QLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309
Query: 998 VSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFIN 1057
S + G+ M+ + + ++T++ E+++ F++ +A LL+
Sbjct: 310 ASILSYDGS----MYMK--------IIMPMVMHTEA----EDVSFRFMSQRAYGLLVATT 353
Query: 1058 SSSQDFVVVLLCKNGSLQ-------VRYHLNKEETHVFTIDADNFANRRMHHLKINREGR 1110
S + L G ++ +R + N + + H +++ R G+
Sbjct: 354 SRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGK 413
Query: 1111 ELTIQMDQQL 1120
L + +D +
Sbjct: 414 SLKLTVDDDV 423
Score = 84.7 bits (208), Expect = 5e-16
Identities = 83/352 (23%), Positives = 148/352 (42%), Gaps = 84/352 (23%)
Query: 190 LYRFNQKLMSTLKDVISLKFKSMQGDGVLF--HGEGQ-----------RGDHITLELQKG 236
L ++N K M + IS F++ + +G++ HG+ Q + D +EL G
Sbjct: 87 LPKWNTKRMGS----ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDG 142
Query: 237 RLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKG 296
L L L++G ++ ++ A +D W+ V I+R G+ +V+ F G
Sbjct: 143 NLYLLLDMGSGTIKVKATQKKA------NDGEWYHVDIQRDGRSGTISVNSRRTPFTASG 196
Query: 297 ETDALDIDYELSFGGIP-------VPGKPGT-FLKKNFHGCIENLYYNG--VNIIDLAKR 346
E++ LD++ ++ GG+P +P + T L + GCI +L+ +G NI LA+
Sbjct: 197 ESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEM 256
Query: 347 RKHQIYTGNVTFSCS---------------------------------------EPQIVP 367
+ V SCS E +
Sbjct: 257 QN----AAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASI 312
Query: 368 ITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRL 427
+++ S +++P + VSF+F + GLL++T + + TL L L+GG ++L
Sbjct: 313 LSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKL 372
Query: 428 VIQKMTERV--------AEILTGSNLNDGLWHSVSINARRNRITLTLDDEAA 471
++ R+ + G LND WH+V + R + LT+DD+ A
Sbjct: 373 MVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424
Score = 83.2 bits (204), Expect = 2e-15
Identities = 81/313 (25%), Positives = 131/313 (41%), Gaps = 57/313 (18%)
Query: 310 GGIPVPGK-PGTFLKKNFHGCIENLYYNGVNI-IDLAKRR-----KHQIYTGNVTFSCSE 362
GG P PG+ + NF GC++ + Y +I ++L++ K +IY G V F C
Sbjct: 11 GGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIY-GEVVFKCEN 69
Query: 363 PQIV-PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLST-------------- 407
+ PI F + +Y+ LP S+SF FRT +GL+L T
Sbjct: 70 VATLDPINF-ETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQK 128
Query: 408 ---------ELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINAR 458
EL +G+ LLL + G +++ K T++ A NDG W+ V I
Sbjct: 129 NTKVDFFAVELLDGNLYLLLDMGSGTIKV---KATQKKA--------NDGEWYHVDIQRD 177
Query: 459 RNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTD--------SQCLNPIKAFQ 510
T++++ P + Y GG P+N + LN +
Sbjct: 178 GRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLN--YGYV 235
Query: 511 GCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNY-CEHGGSCSQSWTTFY 569
GC+R +FID + K++ Q + N + + + + +Y C++ C W F
Sbjct: 236 GCIRDLFIDGRSKNIR--QLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFI 293
Query: 570 CNCSDTSYTGATC 582
C+C+ T Y G TC
Sbjct: 294 CDCTGTGYWGRTC 306
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 19/180 (10%)
Query: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
ST D +++ F + DG+L + G D + L +++G++ + N+G +
Sbjct: 739 STRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERT 798
Query: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKH--TQHFRTKGETDALDIDYELSFGGIPV 314
++D +H V R G VD +H+ T + + +++ GG
Sbjct: 799 P------VNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 852
Query: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSEPQIVPITFVNS 373
+ F G + LYY+G+ ++++A I G+V P I+ T S
Sbjct: 853 G--------RLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTS 904
Score = 40.0 bits (92), Expect = 0.015
Identities = 88/397 (22%), Positives = 134/397 (33%), Gaps = 99/397 (24%)
Query: 808 HAEFSADISFFFKTTALSGVFLENLG--IKDFIRLEISSPSE--------ITFAIDVGNG 857
H E + D+SF F + G+ + D +RLE+ I + G
Sbjct: 330 HTE-AEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKG 388
Query: 858 PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917
P L LNDN+WH VR R K L VD+ T H RL+ ++
Sbjct: 389 PETLYAGQK--LNDNEWHTVRVVRRGKSLKLTVDD--DVAEGTMVGDHTRLEFHNIETGI 444
Query: 918 GTSSRQ-----KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGK 972
T R F+G ++SL NG Y +C NG
Sbjct: 445 MTEKRYISVVPSSFIGHLQSLMFNGLL-----------------------YIDLCKNG-- 479
Query: 973 CVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTD 1032
D + F + + A VT+ + Y +SL++ YT
Sbjct: 480 ----------DIDYCELKARFGLRNIIA-----DPVTFKTKSSY-----LSLATLQAYTS 519
Query: 1033 SAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCK----------NGSLQVRYH--- 1079
++ F TT +LF + DF+ V L K NG ++ +
Sbjct: 520 M-----HLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDR 574
Query: 1080 -LNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSL 1138
LN + H I D N H LK++ + I + L L L
Sbjct: 575 PLNDNQWHNVVITRD---NSNTHSLKVDTKVVTQVINGAKNLDLK------------GDL 619
Query: 1139 TLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAP 1175
+ + + + + A+ GF GC++SV N P
Sbjct: 620 YMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLP 656
>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 140
Score = 105 bits (263), Expect = 2e-22
Identities = 54/137 (39%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Query: 1008 VTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVL 1067
+TY FQE Y +++N S S+++ D ++E I LSF TT+ PSLLL+++S ++++ V+
Sbjct: 1 MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI 60
Query: 1068 LCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNF 1126
L NGSLQ+RY L++ + FT D N A+ ++H +KINRE + ++++Q +
Sbjct: 61 LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 120
Query: 1127 SPEVEFRVIRSLTLGKV 1143
S EF ++SL LGKV
Sbjct: 121 SSGTEFNAVKSLILGKV 137
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 89.0 bits (219), Expect = 3e-17
Identities = 88/362 (24%), Positives = 162/362 (44%), Gaps = 28/362 (7%)
Query: 187 SSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQ-RGDHITLELQKGRLALHLNLG 245
S + FNQ + K + L ++ G++++ Q + D+ L+L GRL +LG
Sbjct: 2722 SHFILPFNQSAVRK-KLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLG 2780
Query: 246 DSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVD-KHTQHFRTKGETDALDID 304
+ ++S +LL D WH+V + V ++ TVD + + G+ LD++
Sbjct: 2781 KGRTKVSHP-------ALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVE 2833
Query: 305 YELSFGGIPVPGKPGTF--LKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSE 362
GG+P + + + CI ++ VN L K +T N ++ ++
Sbjct: 2834 GLFYLGGLPSQYQARKIGNITHSIPACIGDVT---VNSKQLDKDSPVSAFTVNRCYAVAQ 2890
Query: 363 PQIVPITFVNSSG-SYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLE 421
T+ + SG + L+ G ++++ +FRT +++G+LL ++ L ++
Sbjct: 2891 EG----TYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVD 2946
Query: 422 GGILRLVIQKMTERVA--EILTGSNLNDGLWHSVSINARRNRITLTLDDEA-APPAPDST 478
G +L V A E T + L DG WH++ N ++RITL +D A +P +
Sbjct: 2947 GKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQ 3006
Query: 479 WVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSD 538
+ + N Y GG P + +CL +F+GC+R + + P+ VQ +
Sbjct: 3007 STSVDTNNPIYVGGYPAGV-KQKCLRSQTSFRGCLRKLALIKSPQ----VQSFDFSRAFE 3061
Query: 539 LH 540
LH
Sbjct: 3062 LH 3063
Score = 66.6 bits (161), Expect = 1e-10
Identities = 76/363 (20%), Positives = 147/363 (40%), Gaps = 40/363 (11%)
Query: 193 FNQKLMSTLKDVISLKFKSMQGDGVLFH-GEGQRGDHITLELQKGRLALHLNLGDSKARL 251
+ ++ ST + ++L K+ + D +LF+ G D + +E+++GR+A +LG RL
Sbjct: 2130 YQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRL 2189
Query: 252 S-SSLPSATLGSLLDDQHWHSVLIERVG-------KQVNFTVDKHTQHFRTKGETDALDI 303
P +DD WHS+ + R G K+++ T+ ++ G + LD+
Sbjct: 2190 EFPDFP-------IDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDV 2242
Query: 304 DYE--LSFGGIPVPGKPGTFLK-KNFHGCIENLYYNG--VNIIDLAKRRKHQIYTGNVTF 358
+ + GG+ K +K +F GC+ + NG + + + +R G
Sbjct: 2243 NNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIERE------GKCRG 2296
Query: 359 SCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLL 418
Q +F Y ++ + + F T++ +GLLL L +
Sbjct: 2297 CFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSI 2356
Query: 419 SLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDD---------- 468
L G ++ V+ + +LT N+G W+ ++ R + L + D
Sbjct: 2357 ELFRGRVK-VMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETK 2415
Query: 469 EAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISV 528
+ P S ++ + Y GG P + + + K+F GC++ + I DL+
Sbjct: 2416 QGETPGASSDLNRL-DKDPIYVGGLPRSRVVRRGVT-TKSFVGCIKNLEISRSTFDLLRN 2473
Query: 529 QQG 531
G
Sbjct: 2474 SYG 2476
Score = 60.8 bits (146), Expect = 8e-09
Identities = 77/366 (21%), Positives = 143/366 (39%), Gaps = 57/366 (15%)
Query: 209 FKSMQGDGVLFHGEG----QRGDH-------ITLELQKGRLALHLNLGDSKARLSSSLPS 257
F + G++ G +RGD ++ L G + +H+N GD L +L
Sbjct: 2514 FATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTG-LRKALLH 2572
Query: 258 ATLGSLLDDQHWHSVLIERVGKQVNFTVDKHT---QHFRTKGETDALDIDYELSFGGIPV 314
A G+ D Q HS+ + R + + +D++ T E+ +++ L GGIP
Sbjct: 2573 APTGTCSDGQA-HSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVS-NLYVGGIPE 2630
Query: 315 -PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPIT---- 369
G ++++FHGCI+NL +N + ++D H+ + + P++ P
Sbjct: 2631 GEGTSLLTMRRSFHGCIKNLIFN-LELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSK 2689
Query: 370 --------------------------FVNSSGSYLLLPGTPQI--DGLSVSFQFRTWNKD 401
F + S+ +LP LSV RT+
Sbjct: 2690 LLPEPRAFPEQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASS 2749
Query: 402 GLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNR 461
GL+ + +L L GG L + R ++ + L+DG WH+V + + +
Sbjct: 2750 GLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGR-TKVSHPALLSDGKWHTVKTDYVKRK 2808
Query: 462 ITLTLDDEAAPPAP---DSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFI 518
+T+D +P D T + + +Y GG P + N + C+ + +
Sbjct: 2809 GFITVDGRESPMVTVVGDGTMLDV--EGLFYLGGLPSQYQARKIGNITHSIPACIGDVTV 2866
Query: 519 DNQPKD 524
+++ D
Sbjct: 2867 NSKQLD 2872
Score = 52.4 bits (124), Expect = 3e-06
Identities = 97/420 (23%), Positives = 170/420 (40%), Gaps = 55/420 (13%)
Query: 159 WNPSGKIGMRVEVYGCSYKSDVA-DFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGV 217
WN + G +G S D + FDG + + L +T+ +I L F + +G+
Sbjct: 2285 WNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVE--KSLPATVTQIIML-FNTFSPNGL 2341
Query: 218 LFH-GEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIER 276
L + G D +++EL +GR+ + +LG L + ++ W+ + +R
Sbjct: 2342 LLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTD-------RRYNNGTWYKIAFQR 2394
Query: 277 VGKQ-VNFTVDKH-TQHFRTK-GETDALDIDYE-LSFGGIPVPGKPGTFL------KKNF 326
KQ V +D + T + TK GET D L I V G P + + K+F
Sbjct: 2395 NRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSF 2454
Query: 327 HGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQI 386
GCI+NL + + DL + + V C I ++F+ G Y+ LP
Sbjct: 2455 VGCIKNLEISR-STFDLLRN------SYGVRKGCLLEPIRSVSFLK--GGYIELPPKSLS 2505
Query: 387 DGLSVSFQFRTWNKDGLLLST---------ELSEGSGTLL-LSLEGGILRLVIQK----- 431
F T N G++L+ + E + L GG + + +
Sbjct: 2506 PESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTG 2565
Query: 432 MTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN--SYY 489
+ + + TG+ +DG HS+S+ R IT+ LD+ T V+ + N + Y
Sbjct: 2566 LRKALLHAPTGT-CSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLY 2624
Query: 490 FGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDR 549
GG P+ + L ++F GC++ + + + D S + +D C + +R
Sbjct: 2625 VGGIPEG-EGTSLLTMRRSFHGCIKNLIFNLELLDF-----NSAVGHEQVDLDTCWLSER 2678
Score = 50.8 bits (120), Expect = 8e-06
Identities = 41/160 (25%), Positives = 76/160 (47%), Gaps = 25/160 (15%)
Query: 815 ISFFFKTTALSGV--FLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDN 872
I F T + +G+ +L + G KDF+ +E+ + D+G+GP+ L+ N+
Sbjct: 2329 IIMLFNTFSPNGLLLYLGSYGTKDFLSIELFR-GRVKVMTDLGSGPITLLTDRR--YNNG 2385
Query: 873 QWHYVRAERNLKETSLQVDNLPRSTRETSEEGHF--------RLQLNSQLFVGGTSSRQ- 923
W+ + +RN K+ L V + ++ + +++G RL ++VGG +
Sbjct: 2386 TWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLD-KDPIYVGGLPRSRV 2444
Query: 924 -------KGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGC 956
K F+GCI++L ++ DL + + GVR GC
Sbjct: 2445 VRRGVTTKSFVGCIKNLEISRSTFDL---LRNSYGVRKGC 2481
Score = 37.4 bits (85), Expect = 0.095
Identities = 30/131 (22%), Positives = 58/131 (44%), Gaps = 19/131 (14%)
Query: 828 FLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSL-LNDNQWHYVRAER----- 881
+L + DF+ +E+ + F D+G+G L + P ++DN+WH + R
Sbjct: 2157 YLGSSTASDFLAVEMRR-GRVAFLWDLGSGSTRL--EFPDFPIDDNRWHSIHVARFGNIG 2213
Query: 882 --NLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQK--------GFLGCIR 931
++KE S + ++++ + ++ +FVGG + K F GC+
Sbjct: 2214 SLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLG 2273
Query: 932 SLHLNGQKMDL 942
LNG+ + L
Sbjct: 2274 EAFLNGKSIGL 2284
Score = 33.9 bits (76), Expect = 1.0
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 15/138 (10%)
Query: 815 ISFFFKTTALSGV--FLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDN 872
+ +T A SG+ ++ + D+ L++ + F D+G G + V P+LL+D
Sbjct: 2739 VELSIRTFASSGLIYYMAHQNQADYAVLQLHG-GRLHFMFDLGKGRTK--VSHPALLSDG 2795
Query: 873 QWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQK-------- 924
+WH V+ + ++ + VD +G L + ++GG S+ +
Sbjct: 2796 KWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTM-LDVEGLFYLGGLPSQYQARKIGNIT 2854
Query: 925 -GFLGCIRSLHLNGQKMD 941
CI + +N +++D
Sbjct: 2855 HSIPACIGDVTVNSKQLD 2872
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 87.4 bits (215), Expect = 8e-17
Identities = 88/334 (26%), Positives = 142/334 (42%), Gaps = 47/334 (14%)
Query: 801 YLHFPTFHAEFSADISFFFKTTALSGVFLENL--GIKDFIRLEISSPSEITFAIDVGNGP 858
YL F F F D GV L + G KDF+ + ++ + F D G+G
Sbjct: 397 YLSFMEFEITFRPDSG--------DGVLLYSYDTGSKDFLSINLAG-GHVEFRFDCGSGT 447
Query: 859 VELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGG 918
L + P L + WH +R R K LQVD + +E G +++ N+ +F+GG
Sbjct: 448 GVLRSEDPLTLGN--WHELRVSRTAKNGILQVDK-QKIVEGMAEGGFTQIKCNTDIFIGG 504
Query: 919 T---------SSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHN 969
S K F G I+ + LN + + ++ TSGV H + C +
Sbjct: 505 VPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAH-PCVRAPCAH 561
Query: 970 GGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSV--TYMFQEPYPVTKNISLSSS 1027
GG C + GY CDC +EG C+K + E + +Y+ + + K +S
Sbjct: 562 GGSCRPRKEGYDCDCPLG-FEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVS---- 616
Query: 1028 AIYTDSAPSKENIALSFVTTQAPSLLLFINSS----SQDFVVVLLCKNGSLQVRYHLNKE 1083
S+ N+ + F TT LLL+ S + DF+ + L ++G+L Y+L
Sbjct: 617 -------GSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSG 668
Query: 1084 ETHVFTIDADNFANRRMHHLKINREGRELTIQMD 1117
+ +F + R H +K R+G+ I +D
Sbjct: 669 VASIMV--NGSFNDGRWHRVKAVRDGQSGKITVD 700
Score = 60.5 bits (145), Expect = 1e-08
Identities = 78/339 (23%), Positives = 140/339 (41%), Gaps = 38/339 (11%)
Query: 800 SYLHFPTFHAEFSA-DISFFFKTTALSGVFL----ENLGIKDFIRLEISSPSEITFAIDV 854
SY+ F + A I+ F+ A G+ L G DF+ L I S + F +
Sbjct: 161 SYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRS-LQFRFNC 219
Query: 855 GNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQL 914
G G +V ++ L WH V R+ LQ++N T + S+ + ++ + L
Sbjct: 220 GTGVAIIVSETKIKLGG--WHTVMLYRDGLNGLLQLNNGTPVTGQ-SQGQYSKITFRTPL 276
Query: 915 FVGGTSSR---------QKGFLGCIRSLHLNGQKMDLE--ERAKVTSGVRPG-CPGHCSS 962
++GG S +GF GC++SL +NG+++D+ K SG G C
Sbjct: 277 YLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICD 336
Query: 963 YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVS-AVFEAGTSVTYMFQEPYPVTKN 1021
S H G K + Y+C C ++G C+ + + + S+ P+P+
Sbjct: 337 EASCIHGGTCTAIKADSYICLCPLG-FKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQ 395
Query: 1022 ISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLF-INSSSQDFVVVLLCKNGSLQVRYHL 1080
LS ++F +LL+ ++ S+DF+ + L G ++ R+
Sbjct: 396 HYLSFM-----------EFEITFRPDSGDGVLLYSYDTGSKDFLSINLA-GGHVEFRFDC 443
Query: 1081 NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQ 1119
+ + D N H L+++R + +Q+D+Q
Sbjct: 444 GSGTGVLRSEDPLTLGN--WHELRVSRTAKNGILQVDKQ 480
Score = 53.9 bits (128), Expect = 1e-06
Identities = 78/330 (23%), Positives = 120/330 (36%), Gaps = 52/330 (15%)
Query: 207 LKFKSMQGDGVLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLD 265
+ F+ GDGVL + + D +++ L G + + G L S P TLG+
Sbjct: 405 ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDP-LTLGN--- 460
Query: 266 DQHWHSVLIERVGKQVNFTVDKHT-QHFRTKGETDALDIDYELSFGGIPVPG--KPGTFL 322
WH + + R K VDK +G + + ++ GG+P K + +
Sbjct: 461 ---WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGV 517
Query: 323 KKNFHGCIENLYYN------------GVNIIDLAK-------------RRKHQIYT---- 353
K F G I+ + N GVN+ + A R + + Y
Sbjct: 518 LKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCP 577
Query: 354 -GNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQI------DGLSVSFQFRTWNKDGLLL- 405
G C + I I G L P I +V +F+T KDGLLL
Sbjct: 578 LGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLW 637
Query: 406 --STELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRIT 463
+ + S + L L G L + + VA I+ + NDG WH V
Sbjct: 638 RGDSPMRPNSDFISLGLRDGAL-VFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGK 696
Query: 464 LTLDDEAAPPAPDSTWV-QIYSGNSYYFGG 492
+T+DD A + Q+ + Y GG
Sbjct: 697 ITVDDYGARTGKSPGMMRQLNINGALYVGG 726
Score = 52.0 bits (123), Expect = 4e-06
Identities = 87/433 (20%), Positives = 159/433 (36%), Gaps = 67/433 (15%)
Query: 205 ISLKFKSMQGDGVLFH-GEGQ--RGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
I+L+F++ DG+L + GE + RGD ++L + + L N G A + S G
Sbjct: 177 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGG 236
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHF-RTKGETDALDIDYELSFGGIPVPG--KP 318
WH+V++ R G ++ T +++G+ + L GG P
Sbjct: 237 -------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 289
Query: 319 GTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVN------ 372
T + F GC+++L NG ID+ + +G CS + ++
Sbjct: 290 ATGTNRGFQGCVQSLAVNG-RRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTA 348
Query: 373 -SSGSYLLL---------------------------------PGTPQ--IDGLSVSFQFR 396
+ SY+ L P PQ + + FR
Sbjct: 349 IKADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFR 408
Query: 397 TWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSIN 456
+ DG+LL + + L ++L GG + + + L G WH + ++
Sbjct: 409 PDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFD-CGSGTGVLRSEDPLTLGNWHELRVS 467
Query: 457 ARRNRITLTLD-DEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRL 515
L +D + + + QI + GG P+ + +K F G ++
Sbjct: 468 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 527
Query: 516 IFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDT 575
I ++++ I V+ +++ + C+ C HGGSC + C+C
Sbjct: 528 IILNDR---TIHVKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC-PL 578
Query: 576 SYTGATCHNSIYE 588
+ G C +I E
Sbjct: 579 GFEGLHCQKAIIE 591
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 819 FKTTALSGVFLENLGI-----KDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQ 873
FKTTA G+ L DFI L + + + F+ ++G+G ++V ND +
Sbjct: 626 FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGA-LVFSYNLGSGVASIMVNGS--FNDGR 682
Query: 874 WHYVRAERNLKETSLQVDNLPRSTRETSEEGHFR-LQLNSQLFVGGT------SSRQ--K 924
WH V+A R+ + + VD+ R G R L +N L+VGG ++RQ +
Sbjct: 683 WHRVKAVRDGQSGKITVDDY--GARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMR 740
Query: 925 GFLGCIRSLHLN 936
G +GCI L+
Sbjct: 741 GLVGCISHFTLS 752
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 179 DVADFDGRSSLLYRFNQ--KLMSTLKDVISLKFKSMQGDGVL-FHGEGQ---RGDHITLE 232
++ F GRS L Y K +S + + ++FK+ DG+L + G+ D I+L
Sbjct: 594 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 653
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKH-TQH 291
L+ G L NLG S + S + +D WH V R G+ TVD + +
Sbjct: 654 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGART 706
Query: 292 FRTKGETDALDIDYELSFGGI 312
++ G L+I+ L GG+
Sbjct: 707 GKSPGMMRQLNINGALYVGGM 727
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/234 (23%), Positives = 95/234 (40%), Gaps = 15/234 (6%)
Query: 359 SCSEPQIV--PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTL 416
SCSE ++ P F +S ++ L + Q ++ +FR +DGLLL +E
Sbjct: 145 SCSEDIVIQYPQFFGHSYVTFEPLKNSYQ--AFQITLEFRAEAEDGLLLYCGENEHGRGD 202
Query: 417 LLSLEGGILRLVIQ---KMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPP 473
+SL I+R +Q VA I++ + + G WH+V + L L++ P
Sbjct: 203 FMSL--AIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQLNN-GTPV 259
Query: 474 APDST--WVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQG 531
S + +I Y GG P + + FQGC++ + ++ + D+ G
Sbjct: 260 TGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLG 319
Query: 532 SLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNS 585
S + CS C C HGG+C+ Y + G C ++
Sbjct: 320 KA--LSGADVGECS-SGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDA 370
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 87.4 bits (215), Expect = 8e-17
Identities = 88/334 (26%), Positives = 142/334 (42%), Gaps = 47/334 (14%)
Query: 801 YLHFPTFHAEFSADISFFFKTTALSGVFLENL--GIKDFIRLEISSPSEITFAIDVGNGP 858
YL F F F D GV L + G KDF+ + ++ + F D G+G
Sbjct: 631 YLSFMEFEITFRPDSG--------DGVLLYSYDTGSKDFLSINLAG-GHVEFRFDCGSGT 681
Query: 859 VELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGG 918
L + P L + WH +R R K LQVD + +E G +++ N+ +F+GG
Sbjct: 682 GVLRSEDPLTLGN--WHELRVSRTAKNGILQVDK-QKIVEGMAEGGFTQIKCNTDIFIGG 738
Query: 919 T---------SSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHN 969
S K F G I+ + LN + + ++ TSGV H + C +
Sbjct: 739 VPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAH-PCVRAPCAH 795
Query: 970 GGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSV--TYMFQEPYPVTKNISLSSS 1027
GG C + GY CDC +EG C+K + E + +Y+ + + K +S
Sbjct: 796 GGSCRPRKEGYDCDCPLG-FEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVS---- 850
Query: 1028 AIYTDSAPSKENIALSFVTTQAPSLLLFINSS----SQDFVVVLLCKNGSLQVRYHLNKE 1083
S+ N+ + F TT LLL+ S + DF+ + L ++G+L Y+L
Sbjct: 851 -------GSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSG 902
Query: 1084 ETHVFTIDADNFANRRMHHLKINREGRELTIQMD 1117
+ +F + R H +K R+G+ I +D
Sbjct: 903 VASIMV--NGSFNDGRWHRVKAVRDGQSGKITVD 934
Score = 60.5 bits (145), Expect = 1e-08
Identities = 78/339 (23%), Positives = 140/339 (41%), Gaps = 38/339 (11%)
Query: 800 SYLHFPTFHAEFSA-DISFFFKTTALSGVFL----ENLGIKDFIRLEISSPSEITFAIDV 854
SY+ F + A I+ F+ A G+ L G DF+ L I S + F +
Sbjct: 395 SYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRS-LQFRFNC 453
Query: 855 GNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQL 914
G G +V ++ L WH V R+ LQ++N T + S+ + ++ + L
Sbjct: 454 GTGVAIIVSETKIKLGG--WHTVMLYRDGLNGLLQLNNGTPVTGQ-SQGQYSKITFRTPL 510
Query: 915 FVGGTSSR---------QKGFLGCIRSLHLNGQKMDLE--ERAKVTSGVRPG-CPGHCSS 962
++GG S +GF GC++SL +NG+++D+ K SG G C
Sbjct: 511 YLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICD 570
Query: 963 YGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVS-AVFEAGTSVTYMFQEPYPVTKN 1021
S H G K + Y+C C ++G C+ + + + S+ P+P+
Sbjct: 571 EASCIHGGTCTAIKADSYICLCPLG-FKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQ 629
Query: 1022 ISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLF-INSSSQDFVVVLLCKNGSLQVRYHL 1080
LS ++F +LL+ ++ S+DF+ + L G ++ R+
Sbjct: 630 HYLSFM-----------EFEITFRPDSGDGVLLYSYDTGSKDFLSINLA-GGHVEFRFDC 677
Query: 1081 NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQ 1119
+ + D N H L+++R + +Q+D+Q
Sbjct: 678 GSGTGVLRSEDPLTLGN--WHELRVSRTAKNGILQVDKQ 714
Score = 53.9 bits (128), Expect = 1e-06
Identities = 78/330 (23%), Positives = 120/330 (36%), Gaps = 52/330 (15%)
Query: 207 LKFKSMQGDGVLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLD 265
+ F+ GDGVL + + D +++ L G + + G L S P TLG+
Sbjct: 639 ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDP-LTLGN--- 694
Query: 266 DQHWHSVLIERVGKQVNFTVDKHT-QHFRTKGETDALDIDYELSFGGIPVPG--KPGTFL 322
WH + + R K VDK +G + + ++ GG+P K + +
Sbjct: 695 ---WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGV 751
Query: 323 KKNFHGCIENLYYN------------GVNIIDLAK-------------RRKHQIYT---- 353
K F G I+ + N GVN+ + A R + + Y
Sbjct: 752 LKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCP 811
Query: 354 -GNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQI------DGLSVSFQFRTWNKDGLLL- 405
G C + I I G L P I +V +F+T KDGLLL
Sbjct: 812 LGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLW 871
Query: 406 --STELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRIT 463
+ + S + L L G L + + VA I+ + NDG WH V
Sbjct: 872 RGDSPMRPNSDFISLGLRDGAL-VFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGK 930
Query: 464 LTLDDEAAPPAPDSTWV-QIYSGNSYYFGG 492
+T+DD A + Q+ + Y GG
Sbjct: 931 ITVDDYGARTGKSPGMMRQLNINGALYVGG 960
Score = 52.0 bits (123), Expect = 4e-06
Identities = 87/433 (20%), Positives = 159/433 (36%), Gaps = 67/433 (15%)
Query: 205 ISLKFKSMQGDGVLFH-GEGQ--RGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
I+L+F++ DG+L + GE + RGD ++L + + L N G A + S G
Sbjct: 411 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGG 470
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHF-RTKGETDALDIDYELSFGGIPVPG--KP 318
WH+V++ R G ++ T +++G+ + L GG P
Sbjct: 471 -------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 523
Query: 319 GTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVN------ 372
T + F GC+++L NG ID+ + +G CS + ++
Sbjct: 524 ATGTNRGFQGCVQSLAVNG-RRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTA 582
Query: 373 -SSGSYLLL---------------------------------PGTPQ--IDGLSVSFQFR 396
+ SY+ L P PQ + + FR
Sbjct: 583 IKADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFR 642
Query: 397 TWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSIN 456
+ DG+LL + + L ++L GG + + + L G WH + ++
Sbjct: 643 PDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFD-CGSGTGVLRSEDPLTLGNWHELRVS 701
Query: 457 ARRNRITLTLD-DEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRL 515
L +D + + + QI + GG P+ + +K F G ++
Sbjct: 702 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 761
Query: 516 IFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDT 575
I ++++ I V+ +++ + C+ C HGGSC + C+C
Sbjct: 762 IILNDR---TIHVKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC-PL 812
Query: 576 SYTGATCHNSIYE 588
+ G C +I E
Sbjct: 813 GFEGLHCQKAIIE 825
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 819 FKTTALSGVFLENLGI-----KDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQ 873
FKTTA G+ L DFI L + + + F+ ++G+G ++V ND +
Sbjct: 860 FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGA-LVFSYNLGSGVASIMVNGS--FNDGR 916
Query: 874 WHYVRAERNLKETSLQVDNLPRSTRETSEEGHFR-LQLNSQLFVGGT------SSRQ--K 924
WH V+A R+ + + VD+ R G R L +N L+VGG ++RQ +
Sbjct: 917 WHRVKAVRDGQSGKITVDDY--GARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMR 974
Query: 925 GFLGCIRSLHLN 936
G +GCI L+
Sbjct: 975 GLVGCISHFTLS 986
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 179 DVADFDGRSSLLYRFNQ--KLMSTLKDVISLKFKSMQGDGVL-FHGEGQ---RGDHITLE 232
++ F GRS L Y K +S + + ++FK+ DG+L + G+ D I+L
Sbjct: 828 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 887
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKH-TQH 291
L+ G L NLG S + S + +D WH V R G+ TVD + +
Sbjct: 888 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGART 940
Query: 292 FRTKGETDALDIDYELSFGGI 312
++ G L+I+ L GG+
Sbjct: 941 GKSPGMMRQLNINGALYVGGM 961
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/234 (23%), Positives = 95/234 (40%), Gaps = 15/234 (6%)
Query: 359 SCSEPQIV--PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTL 416
SCSE ++ P F +S ++ L + Q ++ +FR +DGLLL +E
Sbjct: 379 SCSEDIVIQYPQFFGHSYVTFEPLKNSYQ--AFQITLEFRAEAEDGLLLYCGENEHGRGD 436
Query: 417 LLSLEGGILRLVIQ---KMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPP 473
+SL I+R +Q VA I++ + + G WH+V + L L++ P
Sbjct: 437 FMSL--AIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQLNN-GTPV 493
Query: 474 APDST--WVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQG 531
S + +I Y GG P + + FQGC++ + ++ + D+ G
Sbjct: 494 TGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLG 553
Query: 532 SLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNS 585
S + CS C C HGG+C+ Y + G C ++
Sbjct: 554 KA--LSGADVGECS-SGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDA 604
>gi|33469935 EGF-like, fibronectin type III and laminin G domains
isoform 3 [Homo sapiens]
Length = 375
Score = 86.3 bits (212), Expect = 2e-16
Identities = 83/316 (26%), Positives = 139/316 (43%), Gaps = 39/316 (12%)
Query: 819 FKTTALSGVFLENL--GIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHY 876
F+ + GV L + G KDF+ + ++ + F D G+G L + P L + WH
Sbjct: 7 FRPDSGDGVLLYSYDTGSKDFLSINLAG-GHVEFRFDCGSGTGVLRSEDPLTLGN--WHE 63
Query: 877 VRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGT---------SSRQKGFL 927
+R R K LQVD + +E G +++ N+ +F+GG S K F
Sbjct: 64 LRVSRTAKNGILQVDK-QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFS 122
Query: 928 GCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNS 987
G I+ + LN + + ++ TSGV H + C +GG C + GY CDC
Sbjct: 123 GSIQKIILNDRTIHVKH--DFTSGVNVENAAH-PCVRAPCAHGGSCRPRKEGYDCDCPLG 179
Query: 988 PYEGPFCKKEVSAVFEAGTSV--TYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFV 1045
+EG C+K + E + +Y+ + + K +S S+ N+ + F
Sbjct: 180 -FEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVS-----------GSRSNVFMRFK 227
Query: 1046 TTQAPSLLLFINSS----SQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMH 1101
TT LLL+ S + DF+ + L ++G+L Y+L + +F + R H
Sbjct: 228 TTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSGVASIMV--NGSFNDGRWH 284
Query: 1102 HLKINREGRELTIQMD 1117
+K R+G+ I +D
Sbjct: 285 RVKAVRDGQSGKITVD 300
Score = 53.9 bits (128), Expect = 1e-06
Identities = 78/330 (23%), Positives = 120/330 (36%), Gaps = 52/330 (15%)
Query: 207 LKFKSMQGDGVLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLD 265
+ F+ GDGVL + + D +++ L G + + G L S P TLG+
Sbjct: 5 ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDP-LTLGN--- 60
Query: 266 DQHWHSVLIERVGKQVNFTVDKHT-QHFRTKGETDALDIDYELSFGGIPVPG--KPGTFL 322
WH + + R K VDK +G + + ++ GG+P K + +
Sbjct: 61 ---WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGV 117
Query: 323 KKNFHGCIENLYYN------------GVNIIDLAK-------------RRKHQIYT---- 353
K F G I+ + N GVN+ + A R + + Y
Sbjct: 118 LKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCP 177
Query: 354 -GNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQI------DGLSVSFQFRTWNKDGLLL- 405
G C + I I G L P I +V +F+T KDGLLL
Sbjct: 178 LGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLW 237
Query: 406 --STELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRIT 463
+ + S + L L G L + + VA I+ + NDG WH V
Sbjct: 238 RGDSPMRPNSDFISLGLRDGAL-VFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGK 296
Query: 464 LTLDDEAAPPAPDSTWV-QIYSGNSYYFGG 492
+T+DD A + Q+ + Y GG
Sbjct: 297 ITVDDYGARTGKSPGMMRQLNINGALYVGG 326
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 819 FKTTALSGVFLENLGI-----KDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQ 873
FKTTA G+ L DFI L + + + F+ ++G+G ++V ND +
Sbjct: 226 FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGA-LVFSYNLGSGVASIMVNGS--FNDGR 282
Query: 874 WHYVRAERNLKETSLQVDNLPRSTRETSEEGHFR-LQLNSQLFVGGT------SSRQ--K 924
WH V+A R+ + + VD+ R G R L +N L+VGG ++RQ +
Sbjct: 283 WHRVKAVRDGQSGKITVDDY--GARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMR 340
Query: 925 GFLGCIRSLHLN 936
G +GCI L+
Sbjct: 341 GLVGCISHFTLS 352
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 179 DVADFDGRSSLLYRFNQ--KLMSTLKDVISLKFKSMQGDGVL-FHGEGQ---RGDHITLE 232
++ F GRS L Y K +S + + ++FK+ DG+L + G+ D I+L
Sbjct: 194 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 253
Query: 233 LQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKH-TQH 291
L+ G L NLG S + S + +D WH V R G+ TVD + +
Sbjct: 254 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGART 306
Query: 292 FRTKGETDALDIDYELSFGGI 312
++ G L+I+ L GG+
Sbjct: 307 GKSPGMMRQLNINGALYVGGM 327
Score = 39.3 bits (90), Expect = 0.025
Identities = 40/195 (20%), Positives = 76/195 (38%), Gaps = 11/195 (5%)
Query: 395 FRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVS 454
FR + DG+LL + + L ++L GG + + + L G WH +
Sbjct: 7 FRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFD-CGSGTGVLRSEDPLTLGNWHELR 65
Query: 455 INARRNRITLTLDDEAAPPA-PDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCM 513
++ L +D + + + QI + GG P+ + +K F G +
Sbjct: 66 VSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSI 125
Query: 514 RLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCS 573
+ I ++++ I V+ +++ + C+ C HGGSC + C+C
Sbjct: 126 QKIILNDRT---IHVKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC- 176
Query: 574 DTSYTGATCHNSIYE 588
+ G C +I E
Sbjct: 177 PLGFEGLHCQKAIIE 191
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 82.0 bits (201), Expect = 3e-15
Identities = 79/328 (24%), Positives = 135/328 (41%), Gaps = 24/328 (7%)
Query: 202 KDVISLKFKSMQGDGVLFH-GEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATL 260
K S++ ++ G++F+ + + D +TL L GRL N+G K ++ S
Sbjct: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ------ 1538
Query: 261 GSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDAL-DIDYELSFGGIPVPGKPG 319
+D WH V+ R +D + T+A I + GG+ PGK
Sbjct: 1539 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGV-APGKAV 1596
Query: 320 TFLKKN----FHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSG 375
++ N F GC+ NL NG +I ++ T +VT C E + T+ ++ G
Sbjct: 1597 KNVQINSIYSFSGCLSNLQLNGASITSASQ-------TFSVT-PCFEGPMETGTYFSTEG 1648
Query: 376 SYLLLPGTPQID-GLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTE 434
Y++L + I ++F+ R + G L+ G + G ++ V + +
Sbjct: 1649 GYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRD 1708
Query: 435 RVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCP 494
+ +L DG WH +++ N + L +D E I + GG P
Sbjct: 1709 FSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVP 1768
Query: 495 DNLTDSQCLNPIKAFQGCMRLIFIDNQP 522
++L + L P K F GC+R ID P
Sbjct: 1769 ESLLTPR-LAPSKPFTGCIRHFVIDGHP 1795
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/311 (21%), Positives = 122/311 (39%), Gaps = 43/311 (13%)
Query: 231 LELQKGRLALHLNLGDS--KARLSSSLPSATLGSLLDDQHWHSV-LIERVGKQVNFTVDK 287
LE++ G L + + G S L +L A + +D +H + +I K++ VD+
Sbjct: 1093 LEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQI----NDAKYHEISIIYHNDKKMILVVDR 1148
Query: 288 HTQHFRTKGETDALDIDY-ELSFGGIPVPGKPGTFLKK------NFHGCIENLYYN--GV 338
+H ++ + + + I + ++ GG P L+ NF GC++ +
Sbjct: 1149 --RHVKSM-DNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDF 1205
Query: 339 NIIDLAKRRKHQIYTGNVTFSCSEPQIVPI-TFVNSSGSYLLLPGTPQIDGLSVSFQFRT 397
N+++ Q T V + C E ++ + N + DG F FRT
Sbjct: 1206 NLLE-------QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRT 1258
Query: 398 WNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINA 457
+GLL + GS +SL+ G + + ++ + + + NDGL H V +
Sbjct: 1259 LQPNGLLF--YYASGSDVFSISLDNGTVIMDVKGIKVQSVD----KQYNDGLSHFVISSV 1312
Query: 458 RRNRITLTLDDE---AAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
R L +D + P S +YFGG P +Q N F GC+
Sbjct: 1313 SPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP---ISAQYAN----FTGCIS 1365
Query: 515 LIFIDNQPKDL 525
+ +D+
Sbjct: 1366 NAYFTRVDRDV 1376
Score = 37.7 bits (86), Expect = 0.073
Identities = 73/333 (21%), Positives = 130/333 (39%), Gaps = 46/333 (13%)
Query: 217 VLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIE 275
+L+ G + + +++ L ++ L NLG + L S + S ++ V IE
Sbjct: 875 ILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIP--LDSKPVSSW--PAYFSIVKIE 930
Query: 276 RVGK--QVNFTV--------DKHTQHFRTKGETDALDIDYE---LSFGGIPVPGKPGTFL 322
RVGK +V TV +K + G+ LD+D E GG+P K T L
Sbjct: 931 RVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSL 990
Query: 323 K-KNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP 381
F GC+E N ++I L + + + C+ ++ F S +
Sbjct: 991 NLPGFVGCLELATLNN-DVISLYNFKHIYNMDPSTSVPCARDKLA---FTQSRAASYFFD 1046
Query: 382 GTPQIDGLSVS------------FQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLV- 428
G+ ++ + RT +GL+L + GS L + G L +
Sbjct: 1047 GSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILL--MVNGSMFFRLEMRNGYLHVFY 1104
Query: 429 ---IQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSG 485
+ + L + +ND +H +SI ++ + + D + D+ ++I
Sbjct: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI-PF 1163
Query: 486 NSYYFGGCPDNLTDSQCLN---PIKA-FQGCMR 514
Y GG P + S+ L P+ F+GCM+
Sbjct: 1164 TDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
Score = 35.8 bits (81), Expect = 0.28
Identities = 40/181 (22%), Positives = 69/181 (38%), Gaps = 28/181 (15%)
Query: 795 FYTEASYLHFP-TFHAEFSADISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAI 852
F TE Y+ +F+ +I+F + + SG + + +++ + + + ++ +
Sbjct: 1644 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKN-GQVIVKV 1702
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+ G V L D +WH + R+ L VD SE H LN
Sbjct: 1703 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD---------SEVNHVVGPLNP 1753
Query: 913 Q-------LFVGGTSSR--------QKGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGC 956
+ +FVGG K F GCIR ++G + + A V+ V C
Sbjct: 1754 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1813
Query: 957 P 957
P
Sbjct: 1814 P 1814
Score = 32.3 bits (72), Expect = 3.0
Identities = 34/155 (21%), Positives = 60/155 (38%), Gaps = 18/155 (11%)
Query: 797 TEASYLHFPTFHAEFSADISFFFKTTALSG----VFLENLGIKDFIRLEISSPSEITFAI 852
T S F +F A F + S ++ + DF+ L ++ + +
Sbjct: 1468 TANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMF 1526
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+VG+ +L ++S ND WH V R L +D L R E+ ++
Sbjct: 1527 NVGHK--KLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGL-RVLEESLPPTEATWKIKG 1583
Query: 913 QLFVGGTSSRQK----------GFLGCIRSLHLNG 937
+++GG + + F GC+ +L LNG
Sbjct: 1584 PIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG 1618
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 82.0 bits (201), Expect = 3e-15
Identities = 79/328 (24%), Positives = 135/328 (41%), Gaps = 24/328 (7%)
Query: 202 KDVISLKFKSMQGDGVLFH-GEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATL 260
K S++ ++ G++F+ + + D +TL L GRL N+G K ++ S
Sbjct: 1492 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ------ 1545
Query: 261 GSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDAL-DIDYELSFGGIPVPGKPG 319
+D WH V+ R +D + T+A I + GG+ PGK
Sbjct: 1546 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGV-APGKAV 1603
Query: 320 TFLKKN----FHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSG 375
++ N F GC+ NL NG +I ++ T +VT C E + T+ ++ G
Sbjct: 1604 KNVQINSIYSFSGCLSNLQLNGASITSASQ-------TFSVT-PCFEGPMETGTYFSTEG 1655
Query: 376 SYLLLPGTPQID-GLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTE 434
Y++L + I ++F+ R + G L+ G + G ++ V + +
Sbjct: 1656 GYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRD 1715
Query: 435 RVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCP 494
+ +L DG WH +++ N + L +D E I + GG P
Sbjct: 1716 FSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVP 1775
Query: 495 DNLTDSQCLNPIKAFQGCMRLIFIDNQP 522
++L + L P K F GC+R ID P
Sbjct: 1776 ESLLTPR-LAPSKPFTGCIRHFVIDGHP 1802
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/311 (21%), Positives = 122/311 (39%), Gaps = 43/311 (13%)
Query: 231 LELQKGRLALHLNLGDS--KARLSSSLPSATLGSLLDDQHWHSV-LIERVGKQVNFTVDK 287
LE++ G L + + G S L +L A + +D +H + +I K++ VD+
Sbjct: 1100 LEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQI----NDAKYHEISIIYHNDKKMILVVDR 1155
Query: 288 HTQHFRTKGETDALDIDY-ELSFGGIPVPGKPGTFLKK------NFHGCIENLYYN--GV 338
+H ++ + + + I + ++ GG P L+ NF GC++ +
Sbjct: 1156 --RHVKSM-DNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDF 1212
Query: 339 NIIDLAKRRKHQIYTGNVTFSCSEPQIVPI-TFVNSSGSYLLLPGTPQIDGLSVSFQFRT 397
N+++ Q T V + C E ++ + N + DG F FRT
Sbjct: 1213 NLLE-------QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRT 1265
Query: 398 WNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINA 457
+GLL + GS +SL+ G + + ++ + + + NDGL H V +
Sbjct: 1266 LQPNGLLF--YYASGSDVFSISLDNGTVIMDVKGIKVQSVD----KQYNDGLSHFVISSV 1319
Query: 458 RRNRITLTLDDE---AAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
R L +D + P S +YFGG P +Q N F GC+
Sbjct: 1320 SPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP---ISAQYAN----FTGCIS 1372
Query: 515 LIFIDNQPKDL 525
+ +D+
Sbjct: 1373 NAYFTRVDRDV 1383
Score = 37.7 bits (86), Expect = 0.073
Identities = 73/333 (21%), Positives = 130/333 (39%), Gaps = 46/333 (13%)
Query: 217 VLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIE 275
+L+ G + + +++ L ++ L NLG + L S + S ++ V IE
Sbjct: 882 ILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIP--LDSKPVSSW--PAYFSIVKIE 937
Query: 276 RVGK--QVNFTV--------DKHTQHFRTKGETDALDIDYE---LSFGGIPVPGKPGTFL 322
RVGK +V TV +K + G+ LD+D E GG+P K T L
Sbjct: 938 RVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSL 997
Query: 323 K-KNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP 381
F GC+E N ++I L + + + C+ ++ F S +
Sbjct: 998 NLPGFVGCLELATLNN-DVISLYNFKHIYNMDPSTSVPCARDKLA---FTQSRAASYFFD 1053
Query: 382 GTPQIDGLSVS------------FQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLV- 428
G+ ++ + RT +GL+L + GS L + G L +
Sbjct: 1054 GSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILL--MVNGSMFFRLEMRNGYLHVFY 1111
Query: 429 ---IQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSG 485
+ + L + +ND +H +SI ++ + + D + D+ ++I
Sbjct: 1112 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI-PF 1170
Query: 486 NSYYFGGCPDNLTDSQCLN---PIKA-FQGCMR 514
Y GG P + S+ L P+ F+GCM+
Sbjct: 1171 TDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1203
Score = 35.8 bits (81), Expect = 0.28
Identities = 40/181 (22%), Positives = 69/181 (38%), Gaps = 28/181 (15%)
Query: 795 FYTEASYLHFP-TFHAEFSADISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAI 852
F TE Y+ +F+ +I+F + + SG + + +++ + + + ++ +
Sbjct: 1651 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKN-GQVIVKV 1709
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+ G V L D +WH + R+ L VD SE H LN
Sbjct: 1710 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD---------SEVNHVVGPLNP 1760
Query: 913 Q-------LFVGGTSSR--------QKGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGC 956
+ +FVGG K F GCIR ++G + + A V+ V C
Sbjct: 1761 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1820
Query: 957 P 957
P
Sbjct: 1821 P 1821
Score = 32.3 bits (72), Expect = 3.0
Identities = 34/155 (21%), Positives = 60/155 (38%), Gaps = 18/155 (11%)
Query: 797 TEASYLHFPTFHAEFSADISFFFKTTALSG----VFLENLGIKDFIRLEISSPSEITFAI 852
T S F +F A F + S ++ + DF+ L ++ + +
Sbjct: 1475 TANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMF 1533
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+VG+ +L ++S ND WH V R L +D L R E+ ++
Sbjct: 1534 NVGHK--KLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGL-RVLEESLPPTEATWKIKG 1590
Query: 913 QLFVGGTSSRQK----------GFLGCIRSLHLNG 937
+++GG + + F GC+ +L LNG
Sbjct: 1591 PIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG 1625
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 82.0 bits (201), Expect = 3e-15
Identities = 79/328 (24%), Positives = 135/328 (41%), Gaps = 24/328 (7%)
Query: 202 KDVISLKFKSMQGDGVLFH-GEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATL 260
K S++ ++ G++F+ + + D +TL L GRL N+G K ++ S
Sbjct: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ------ 1538
Query: 261 GSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDAL-DIDYELSFGGIPVPGKPG 319
+D WH V+ R +D + T+A I + GG+ PGK
Sbjct: 1539 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGV-APGKAV 1596
Query: 320 TFLKKN----FHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSG 375
++ N F GC+ NL NG +I ++ T +VT C E + T+ ++ G
Sbjct: 1597 KNVQINSIYSFSGCLSNLQLNGASITSASQ-------TFSVT-PCFEGPMETGTYFSTEG 1648
Query: 376 SYLLLPGTPQID-GLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTE 434
Y++L + I ++F+ R + G L+ G + G ++ V + +
Sbjct: 1649 GYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRD 1708
Query: 435 RVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCP 494
+ +L DG WH +++ N + L +D E I + GG P
Sbjct: 1709 FSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVP 1768
Query: 495 DNLTDSQCLNPIKAFQGCMRLIFIDNQP 522
++L + L P K F GC+R ID P
Sbjct: 1769 ESLLTPR-LAPSKPFTGCIRHFVIDGHP 1795
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/311 (21%), Positives = 122/311 (39%), Gaps = 43/311 (13%)
Query: 231 LELQKGRLALHLNLGDS--KARLSSSLPSATLGSLLDDQHWHSV-LIERVGKQVNFTVDK 287
LE++ G L + + G S L +L A + +D +H + +I K++ VD+
Sbjct: 1093 LEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQI----NDAKYHEISIIYHNDKKMILVVDR 1148
Query: 288 HTQHFRTKGETDALDIDY-ELSFGGIPVPGKPGTFLKK------NFHGCIENLYYN--GV 338
+H ++ + + + I + ++ GG P L+ NF GC++ +
Sbjct: 1149 --RHVKSM-DNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDF 1205
Query: 339 NIIDLAKRRKHQIYTGNVTFSCSEPQIVPI-TFVNSSGSYLLLPGTPQIDGLSVSFQFRT 397
N+++ Q T V + C E ++ + N + DG F FRT
Sbjct: 1206 NLLE-------QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRT 1258
Query: 398 WNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINA 457
+GLL + GS +SL+ G + + ++ + + + NDGL H V +
Sbjct: 1259 LQPNGLLF--YYASGSDVFSISLDNGTVIMDVKGIKVQSVD----KQYNDGLSHFVISSV 1312
Query: 458 RRNRITLTLDDE---AAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
R L +D + P S +YFGG P +Q N F GC+
Sbjct: 1313 SPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP---ISAQYAN----FTGCIS 1365
Query: 515 LIFIDNQPKDL 525
+ +D+
Sbjct: 1366 NAYFTRVDRDV 1376
Score = 37.7 bits (86), Expect = 0.073
Identities = 73/333 (21%), Positives = 130/333 (39%), Gaps = 46/333 (13%)
Query: 217 VLFHG-EGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIE 275
+L+ G + + +++ L ++ L NLG + L S + S ++ V IE
Sbjct: 875 ILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIP--LDSKPVSSW--PAYFSIVKIE 930
Query: 276 RVGK--QVNFTV--------DKHTQHFRTKGETDALDIDYE---LSFGGIPVPGKPGTFL 322
RVGK +V TV +K + G+ LD+D E GG+P K T L
Sbjct: 931 RVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSL 990
Query: 323 K-KNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP 381
F GC+E N ++I L + + + C+ ++ F S +
Sbjct: 991 NLPGFVGCLELATLNN-DVISLYNFKHIYNMDPSTSVPCARDKLA---FTQSRAASYFFD 1046
Query: 382 GTPQIDGLSVS------------FQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLV- 428
G+ ++ + RT +GL+L + GS L + G L +
Sbjct: 1047 GSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILL--MVNGSMFFRLEMRNGYLHVFY 1104
Query: 429 ---IQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSG 485
+ + L + +ND +H +SI ++ + + D + D+ ++I
Sbjct: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI-PF 1163
Query: 486 NSYYFGGCPDNLTDSQCLN---PIKA-FQGCMR 514
Y GG P + S+ L P+ F+GCM+
Sbjct: 1164 TDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
Score = 35.8 bits (81), Expect = 0.28
Identities = 40/181 (22%), Positives = 69/181 (38%), Gaps = 28/181 (15%)
Query: 795 FYTEASYLHFP-TFHAEFSADISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAI 852
F TE Y+ +F+ +I+F + + SG + + +++ + + + ++ +
Sbjct: 1644 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKN-GQVIVKV 1702
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+ G V L D +WH + R+ L VD SE H LN
Sbjct: 1703 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD---------SEVNHVVGPLNP 1753
Query: 913 Q-------LFVGGTSSR--------QKGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGC 956
+ +FVGG K F GCIR ++G + + A V+ V C
Sbjct: 1754 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1813
Query: 957 P 957
P
Sbjct: 1814 P 1814
Score = 32.3 bits (72), Expect = 3.0
Identities = 34/155 (21%), Positives = 60/155 (38%), Gaps = 18/155 (11%)
Query: 797 TEASYLHFPTFHAEFSADISFFFKTTALSG----VFLENLGIKDFIRLEISSPSEITFAI 852
T S F +F A F + S ++ + DF+ L ++ + +
Sbjct: 1468 TANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMF 1526
Query: 853 DVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNS 912
+VG+ +L ++S ND WH V R L +D L R E+ ++
Sbjct: 1527 NVGHK--KLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGL-RVLEESLPPTEATWKIKG 1583
Query: 913 QLFVGGTSSRQK----------GFLGCIRSLHLNG 937
+++GG + + F GC+ +L LNG
Sbjct: 1584 PIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG 1618
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 80.5 bits (197), Expect = 1e-14
Identities = 44/113 (38%), Positives = 60/113 (53%), Gaps = 4/113 (3%)
Query: 65 GGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGS--SDWVTSYSLMFSDTGRNWKQYKQ 122
G W D QW+++D T V TQGR S D+VT++ + FS+ + W Y
Sbjct: 431 GAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTN 490
Query: 123 EDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCS 175
TF GN++ D+ V +L V ARF+R PL WN G + MR+EV GCS
Sbjct: 491 GYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWN--GSLCMRLEVLGCS 541
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 77.4 bits (189), Expect = 8e-14
Identities = 40/112 (35%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 65 GGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGS--SDWVTSYSLMFSDTGRNWKQYKQ 122
G W ++ QQW+++D T V TQGR SDWVTSY +M S+ W K
Sbjct: 182 GAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN 241
Query: 123 EDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGC 174
F GN + V ++L + AR++R P W +G I MR+E+ GC
Sbjct: 242 GSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 77.0 bits (188), Expect = 1e-13
Identities = 80/342 (23%), Positives = 140/342 (40%), Gaps = 30/342 (8%)
Query: 187 SSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGD 246
S LL++ Q+L+ + ++ ++ G++FH G + + L L KGRL L
Sbjct: 2995 SHLLFKLPQELLKP-RSQFAVDMQTTSSRGLVFH-TGTKNSFMALYLSKGRLVFALGTDG 3052
Query: 247 SKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYE 306
K R+ S +D WH+V+ G++ VD + + I
Sbjct: 3053 KKLRIKSK-------EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3105
Query: 307 LSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSE---- 362
+ G P GKP + +F GC++N + +YT + +F S
Sbjct: 3106 VYLGS-PPSGKPKSLPTNSFVGCLKNFQLDS-----------KPLYTPSSSFGVSSCLGG 3153
Query: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
P I F G +L + F R + G+L+ G L + LE
Sbjct: 3154 PLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKH-LCVYLEA 3212
Query: 423 GILRLVIQKMTERVAEILTGS-NLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQ 481
G + + + +T +L DG WHSV++ +++ + L LD +++ A +
Sbjct: 3213 GKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPP 3272
Query: 482 IYSGNSYYFGGCPDNLTDSQCLNPI-KAFQGCMRLIFIDNQP 522
+ + GG P NLT + P+ K+F GC+R I +++ P
Sbjct: 3273 ASTQEPLHLGGAPANLTTLRI--PVWKSFFGCLRNIHVNHIP 3312
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 31/260 (11%)
Query: 216 GVLFHGEGQRGDH-ITLELQKGRLALHLNLGDSKARLSSSLPSAT-LGSLLDDQHWHSVL 273
G+LF E GD I+L ++ G+L + + +L+S LP +G +++ HS+
Sbjct: 2633 GLLFFAEN--GDRFISLNIEDGKLMV-------RYKLNSELPKERGVGDAINNGRDHSIQ 2683
Query: 274 IERVGK-QVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKN-FHGCIE 331
I ++GK Q ++ Q+ GE Y GGIP+ + + F GC++
Sbjct: 2684 I-KIGKLQKRMWINVDVQNTIIDGEVFDFSTYY---LGGIPIAIRERFNISTPAFRGCMK 2739
Query: 332 NLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP--GTPQIDGL 389
NL ++ L T VT CSE + + S G L G P D L
Sbjct: 2740 NLKKTS-GVVRLND-------TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHL 2791
Query: 390 SVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGL 449
SF F+T+ G+LL + + L ++LE G + L + + + DGL
Sbjct: 2792 QASFGFQTFQPSGILLDHQ--TWTRNLQVTLEDGYIELSTSDSGSPIFK--SPQTYMDGL 2847
Query: 450 WHSVSINARRNRITLTLDDE 469
H VS+ + + + L +DD+
Sbjct: 2848 LHYVSVISDNSGLRLLIDDQ 2867
Score = 46.6 bits (109), Expect = 2e-04
Identities = 86/392 (21%), Positives = 152/392 (38%), Gaps = 73/392 (18%)
Query: 155 VPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSL---LYRFNQKLMSTLKDVISLKFKS 211
VP+ +N GK G+ V + +D+ D G +SL L R N + +++
Sbjct: 2389 VPMRFN--GKSGVEVRL-----PNDLEDLKGYTSLSLFLQRPNSRENGGTENMF------ 2435
Query: 212 MQGDGVLFHGEGQRG-DHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWH 270
V++ G D+I + + G+L NLGD +A L + +L
Sbjct: 2436 -----VMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQ-------VDQILTKSETK 2483
Query: 271 SVLIERVGKQ-------VNFTVDKHTQHFRTKGETD--------ALDIDYE---LSFGGI 312
+++RV Q +N+T + T G D L++D E GG
Sbjct: 2484 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 2543
Query: 313 PVPGK-PGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPI--- 368
P K P + GCIE +D +Y TF+ + ++ P
Sbjct: 2544 PPDFKLPSRLSFPPYKGCIE---------LDDLNENVLSLYNFKKTFNLNTTEVEPCRRR 2594
Query: 369 ------TFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
+ +G Y +P P + +T GLL E G + L++E
Sbjct: 2595 KEESDKNYFEGTG-YARVPTQPHAPIPTFGQTIQTTVDRGLLFFAE--NGDRFISLNIED 2651
Query: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482
G L + + +E E G +N+G HS+ I + + + ++ + D ++
Sbjct: 2652 GKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDG---EV 2708
Query: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
+ ++YY GG P + + ++ AF+GCM+
Sbjct: 2709 FDFSTYYLGGIPIAIRERFNIS-TPAFRGCMK 2739
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 40/156 (25%)
Query: 202 KDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
K V S++ +S+ G +L H Q G H+ + L+ G++ ++ G + S T
Sbjct: 3181 KLVFSIRPRSLTG--ILIHIGSQPGKHLCVYLEAGKVTASMDSG-----AGGTSTSVTPK 3233
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVP------ 315
L D WHSV + T+ +H H LD D + G IP P
Sbjct: 3234 QSLCDGQWHSVAV---------TIKQHILHLE-------LDTDSSYTAGQIPFPPASTQE 3277
Query: 316 -----GKPGTFLK------KNFHGCIENLYYNGVNI 340
G P K+F GC+ N++ N + +
Sbjct: 3278 PLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPV 3313
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 15/138 (10%)
Query: 809 AEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSL 868
++F+ D+ +TT+ G+ F+ L +S + FA+ G +L ++S
Sbjct: 3010 SQFAVDM----QTTSSRGLVFHTGTKNSFMALYLSK-GRLVFAL--GTDGKKLRIKSKEK 3062
Query: 869 LNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQ----- 923
ND +WH V + ++ L VD L RE S G+ + + + +++G S +
Sbjct: 3063 CNDGKWHTVVFGHDGEKGRLVVDGL--RAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3120
Query: 924 -KGFLGCIRSLHLNGQKM 940
F+GC+++ L+ + +
Sbjct: 3121 TNSFVGCLKNFQLDSKPL 3138
Score = 36.6 bits (83), Expect = 0.16
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 847 EITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHF 906
++T ++D G G V L D QWH V +K+ L ++ S+ +
Sbjct: 3214 KVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAV--TIKQHILHLELDTDSSYTAGQIPFP 3271
Query: 907 RLQLNSQLFVGGTSSRQ--------KGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGCP 957
L +GG + K F GC+R++H+N + + E +V V GCP
Sbjct: 3272 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 3331
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 77.0 bits (188), Expect = 1e-13
Identities = 80/342 (23%), Positives = 140/342 (40%), Gaps = 30/342 (8%)
Query: 187 SSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGD 246
S LL++ Q+L+ + ++ ++ G++FH G + + L L KGRL L
Sbjct: 1330 SHLLFKLPQELLKP-RSQFAVDMQTTSSRGLVFH-TGTKNSFMALYLSKGRLVFALGTDG 1387
Query: 247 SKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYE 306
K R+ S +D WH+V+ G++ VD + + I
Sbjct: 1388 KKLRIKSK-------EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1440
Query: 307 LSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSE---- 362
+ G P GKP + +F GC++N + +YT + +F S
Sbjct: 1441 VYLGS-PPSGKPKSLPTNSFVGCLKNFQLDS-----------KPLYTPSSSFGVSSCLGG 1488
Query: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
P I F G +L + F R + G+L+ G L + LE
Sbjct: 1489 PLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKH-LCVYLEA 1547
Query: 423 GILRLVIQKMTERVAEILTGS-NLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQ 481
G + + + +T +L DG WHSV++ +++ + L LD +++ A +
Sbjct: 1548 GKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPP 1607
Query: 482 IYSGNSYYFGGCPDNLTDSQCLNPI-KAFQGCMRLIFIDNQP 522
+ + GG P NLT + P+ K+F GC+R I +++ P
Sbjct: 1608 ASTQEPLHLGGAPANLTTLRI--PVWKSFFGCLRNIHVNHIP 1647
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 31/260 (11%)
Query: 216 GVLFHGEGQRGDH-ITLELQKGRLALHLNLGDSKARLSSSLPSAT-LGSLLDDQHWHSVL 273
G+LF E GD I+L ++ G+L + + +L+S LP +G +++ HS+
Sbjct: 968 GLLFFAEN--GDRFISLNIEDGKLMV-------RYKLNSELPKERGVGDAINNGRDHSIQ 1018
Query: 274 IERVGK-QVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKN-FHGCIE 331
I ++GK Q ++ Q+ GE Y GGIP+ + + F GC++
Sbjct: 1019 I-KIGKLQKRMWINVDVQNTIIDGEVFDFSTYY---LGGIPIAIRERFNISTPAFRGCMK 1074
Query: 332 NLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP--GTPQIDGL 389
NL ++ L T VT CSE + + S G L G P D L
Sbjct: 1075 NLKKTS-GVVRLND-------TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHL 1126
Query: 390 SVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGL 449
SF F+T+ G+LL + + L ++LE G + L + + + DGL
Sbjct: 1127 QASFGFQTFQPSGILLDHQ--TWTRNLQVTLEDGYIELSTSDSGSPIFK--SPQTYMDGL 1182
Query: 450 WHSVSINARRNRITLTLDDE 469
H VS+ + + + L +DD+
Sbjct: 1183 LHYVSVISDNSGLRLLIDDQ 1202
Score = 46.6 bits (109), Expect = 2e-04
Identities = 86/392 (21%), Positives = 152/392 (38%), Gaps = 73/392 (18%)
Query: 155 VPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSL---LYRFNQKLMSTLKDVISLKFKS 211
VP+ +N GK G+ V + +D+ D G +SL L R N + +++
Sbjct: 724 VPMRFN--GKSGVEVRL-----PNDLEDLKGYTSLSLFLQRPNSRENGGTENMF------ 770
Query: 212 MQGDGVLFHGEGQRG-DHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWH 270
V++ G D+I + + G+L NLGD +A L + +L
Sbjct: 771 -----VMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQ-------VDQILTKSETK 818
Query: 271 SVLIERVGKQ-------VNFTVDKHTQHFRTKGETD--------ALDIDYE---LSFGGI 312
+++RV Q +N+T + T G D L++D E GG
Sbjct: 819 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 878
Query: 313 PVPGK-PGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPI--- 368
P K P + GCIE +D +Y TF+ + ++ P
Sbjct: 879 PPDFKLPSRLSFPPYKGCIE---------LDDLNENVLSLYNFKKTFNLNTTEVEPCRRR 929
Query: 369 ------TFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
+ +G Y +P P + +T GLL E G + L++E
Sbjct: 930 KEESDKNYFEGTG-YARVPTQPHAPIPTFGQTIQTTVDRGLLFFAE--NGDRFISLNIED 986
Query: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482
G L + + +E E G +N+G HS+ I + + + ++ + D ++
Sbjct: 987 GKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDG---EV 1043
Query: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
+ ++YY GG P + + ++ AF+GCM+
Sbjct: 1044 FDFSTYYLGGIPIAIRERFNIS-TPAFRGCMK 1074
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 40/156 (25%)
Query: 202 KDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
K V S++ +S+ G +L H Q G H+ + L+ G++ ++ G + S T
Sbjct: 1516 KLVFSIRPRSLTG--ILIHIGSQPGKHLCVYLEAGKVTASMDSG-----AGGTSTSVTPK 1568
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVP------ 315
L D WHSV + T+ +H H LD D + G IP P
Sbjct: 1569 QSLCDGQWHSVAV---------TIKQHILHLE-------LDTDSSYTAGQIPFPPASTQE 1612
Query: 316 -----GKPGTFLK------KNFHGCIENLYYNGVNI 340
G P K+F GC+ N++ N + +
Sbjct: 1613 PLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPV 1648
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 15/138 (10%)
Query: 809 AEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSL 868
++F+ D+ +TT+ G+ F+ L +S + FA+ G +L ++S
Sbjct: 1345 SQFAVDM----QTTSSRGLVFHTGTKNSFMALYLSK-GRLVFAL--GTDGKKLRIKSKEK 1397
Query: 869 LNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQ----- 923
ND +WH V + ++ L VD L RE S G+ + + + +++G S +
Sbjct: 1398 CNDGKWHTVVFGHDGEKGRLVVDGL--RAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 1455
Query: 924 -KGFLGCIRSLHLNGQKM 940
F+GC+++ L+ + +
Sbjct: 1456 TNSFVGCLKNFQLDSKPL 1473
Score = 36.6 bits (83), Expect = 0.16
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 847 EITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHF 906
++T ++D G G V L D QWH V +K+ L ++ S+ +
Sbjct: 1549 KVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAV--TIKQHILHLELDTDSSYTAGQIPFP 1606
Query: 907 RLQLNSQLFVGGTSSRQ--------KGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGCP 957
L +GG + K F GC+R++H+N + + E +V V GCP
Sbjct: 1607 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 77.0 bits (188), Expect = 1e-13
Identities = 80/342 (23%), Positives = 140/342 (40%), Gaps = 30/342 (8%)
Query: 187 SSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGD 246
S LL++ Q+L+ + ++ ++ G++FH G + + L L KGRL L
Sbjct: 2939 SHLLFKLPQELLKP-RSQFAVDMQTTSSRGLVFH-TGTKNSFMALYLSKGRLVFALGTDG 2996
Query: 247 SKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYE 306
K R+ S +D WH+V+ G++ VD + + I
Sbjct: 2997 KKLRIKSK-------EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3049
Query: 307 LSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSE---- 362
+ G P GKP + +F GC++N + +YT + +F S
Sbjct: 3050 VYLGS-PPSGKPKSLPTNSFVGCLKNFQLDS-----------KPLYTPSSSFGVSSCLGG 3097
Query: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
P I F G +L + F R + G+L+ G L + LE
Sbjct: 3098 PLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKH-LCVYLEA 3156
Query: 423 GILRLVIQKMTERVAEILTGS-NLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQ 481
G + + + +T +L DG WHSV++ +++ + L LD +++ A +
Sbjct: 3157 GKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPP 3216
Query: 482 IYSGNSYYFGGCPDNLTDSQCLNPI-KAFQGCMRLIFIDNQP 522
+ + GG P NLT + P+ K+F GC+R I +++ P
Sbjct: 3217 ASTQEPLHLGGAPANLTTLRI--PVWKSFFGCLRNIHVNHIP 3256
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 31/260 (11%)
Query: 216 GVLFHGEGQRGDH-ITLELQKGRLALHLNLGDSKARLSSSLPSAT-LGSLLDDQHWHSVL 273
G+LF E GD I+L ++ G+L + + +L+S LP +G +++ HS+
Sbjct: 2577 GLLFFAEN--GDRFISLNIEDGKLMV-------RYKLNSELPKERGVGDAINNGRDHSIQ 2627
Query: 274 IERVGK-QVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKN-FHGCIE 331
I ++GK Q ++ Q+ GE Y GGIP+ + + F GC++
Sbjct: 2628 I-KIGKLQKRMWINVDVQNTIIDGEVFDFSTYY---LGGIPIAIRERFNISTPAFRGCMK 2683
Query: 332 NLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP--GTPQIDGL 389
NL ++ L T VT CSE + + S G L G P D L
Sbjct: 2684 NLKKTS-GVVRLND-------TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHL 2735
Query: 390 SVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGL 449
SF F+T+ G+LL + + L ++LE G + L + + + DGL
Sbjct: 2736 QASFGFQTFQPSGILLDHQ--TWTRNLQVTLEDGYIELSTSDSGSPIFK--SPQTYMDGL 2791
Query: 450 WHSVSINARRNRITLTLDDE 469
H VS+ + + + L +DD+
Sbjct: 2792 LHYVSVISDNSGLRLLIDDQ 2811
Score = 46.6 bits (109), Expect = 2e-04
Identities = 86/392 (21%), Positives = 152/392 (38%), Gaps = 73/392 (18%)
Query: 155 VPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSL---LYRFNQKLMSTLKDVISLKFKS 211
VP+ +N GK G+ V + +D+ D G +SL L R N + +++
Sbjct: 2333 VPMRFN--GKSGVEVRL-----PNDLEDLKGYTSLSLFLQRPNSRENGGTENMF------ 2379
Query: 212 MQGDGVLFHGEGQRG-DHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWH 270
V++ G D+I + + G+L NLGD +A L + +L
Sbjct: 2380 -----VMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQ-------VDQILTKSETK 2427
Query: 271 SVLIERVGKQ-------VNFTVDKHTQHFRTKGETD--------ALDIDYE---LSFGGI 312
+++RV Q +N+T + T G D L++D E GG
Sbjct: 2428 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 2487
Query: 313 PVPGK-PGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPI--- 368
P K P + GCIE +D +Y TF+ + ++ P
Sbjct: 2488 PPDFKLPSRLSFPPYKGCIE---------LDDLNENVLSLYNFKKTFNLNTTEVEPCRRR 2538
Query: 369 ------TFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
+ +G Y +P P + +T GLL E G + L++E
Sbjct: 2539 KEESDKNYFEGTG-YARVPTQPHAPIPTFGQTIQTTVDRGLLFFAE--NGDRFISLNIED 2595
Query: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482
G L + + +E E G +N+G HS+ I + + + ++ + D ++
Sbjct: 2596 GKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDG---EV 2652
Query: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
+ ++YY GG P + + ++ AF+GCM+
Sbjct: 2653 FDFSTYYLGGIPIAIRERFNIS-TPAFRGCMK 2683
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 40/156 (25%)
Query: 202 KDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
K V S++ +S+ G +L H Q G H+ + L+ G++ ++ G + S T
Sbjct: 3125 KLVFSIRPRSLTG--ILIHIGSQPGKHLCVYLEAGKVTASMDSG-----AGGTSTSVTPK 3177
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVP------ 315
L D WHSV + T+ +H H LD D + G IP P
Sbjct: 3178 QSLCDGQWHSVAV---------TIKQHILHLE-------LDTDSSYTAGQIPFPPASTQE 3221
Query: 316 -----GKPGTFLK------KNFHGCIENLYYNGVNI 340
G P K+F GC+ N++ N + +
Sbjct: 3222 PLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPV 3257
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 15/138 (10%)
Query: 809 AEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSL 868
++F+ D+ +TT+ G+ F+ L +S + FA+ G +L ++S
Sbjct: 2954 SQFAVDM----QTTSSRGLVFHTGTKNSFMALYLSK-GRLVFAL--GTDGKKLRIKSKEK 3006
Query: 869 LNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQ----- 923
ND +WH V + ++ L VD L RE S G+ + + + +++G S +
Sbjct: 3007 CNDGKWHTVVFGHDGEKGRLVVDGL--RAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3064
Query: 924 -KGFLGCIRSLHLNGQKM 940
F+GC+++ L+ + +
Sbjct: 3065 TNSFVGCLKNFQLDSKPL 3082
Score = 36.6 bits (83), Expect = 0.16
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 847 EITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHF 906
++T ++D G G V L D QWH V +K+ L ++ S+ +
Sbjct: 3158 KVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAV--TIKQHILHLELDTDSSYTAGQIPFP 3215
Query: 907 RLQLNSQLFVGGTSSRQ--------KGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGCP 957
L +GG + K F GC+R++H+N + + E +V V GCP
Sbjct: 3216 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 3275
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 77.0 bits (188), Expect = 1e-13
Identities = 80/342 (23%), Positives = 140/342 (40%), Gaps = 30/342 (8%)
Query: 187 SSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGD 246
S LL++ Q+L+ + ++ ++ G++FH G + + L L KGRL L
Sbjct: 1386 SHLLFKLPQELLKP-RSQFAVDMQTTSSRGLVFH-TGTKNSFMALYLSKGRLVFALGTDG 1443
Query: 247 SKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYE 306
K R+ S +D WH+V+ G++ VD + + I
Sbjct: 1444 KKLRIKSK-------EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1496
Query: 307 LSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSE---- 362
+ G P GKP + +F GC++N + +YT + +F S
Sbjct: 1497 VYLGS-PPSGKPKSLPTNSFVGCLKNFQLDS-----------KPLYTPSSSFGVSSCLGG 1544
Query: 363 PQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
P I F G +L + F R + G+L+ G L + LE
Sbjct: 1545 PLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKH-LCVYLEA 1603
Query: 423 GILRLVIQKMTERVAEILTGS-NLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQ 481
G + + + +T +L DG WHSV++ +++ + L LD +++ A +
Sbjct: 1604 GKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPP 1663
Query: 482 IYSGNSYYFGGCPDNLTDSQCLNPI-KAFQGCMRLIFIDNQP 522
+ + GG P NLT + P+ K+F GC+R I +++ P
Sbjct: 1664 ASTQEPLHLGGAPANLTTLRI--PVWKSFFGCLRNIHVNHIP 1703
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 31/260 (11%)
Query: 216 GVLFHGEGQRGDH-ITLELQKGRLALHLNLGDSKARLSSSLPSAT-LGSLLDDQHWHSVL 273
G+LF E GD I+L ++ G+L + + +L+S LP +G +++ HS+
Sbjct: 1024 GLLFFAEN--GDRFISLNIEDGKLMV-------RYKLNSELPKERGVGDAINNGRDHSIQ 1074
Query: 274 IERVGK-QVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKN-FHGCIE 331
I ++GK Q ++ Q+ GE Y GGIP+ + + F GC++
Sbjct: 1075 I-KIGKLQKRMWINVDVQNTIIDGEVFDFSTYY---LGGIPIAIRERFNISTPAFRGCMK 1130
Query: 332 NLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLP--GTPQIDGL 389
NL ++ L T VT CSE + + S G L G P D L
Sbjct: 1131 NLKKTS-GVVRLND-------TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHL 1182
Query: 390 SVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGL 449
SF F+T+ G+LL + + L ++LE G + L + + + DGL
Sbjct: 1183 QASFGFQTFQPSGILLDHQ--TWTRNLQVTLEDGYIELSTSDSGSPIFK--SPQTYMDGL 1238
Query: 450 WHSVSINARRNRITLTLDDE 469
H VS+ + + + L +DD+
Sbjct: 1239 LHYVSVISDNSGLRLLIDDQ 1258
Score = 46.6 bits (109), Expect = 2e-04
Identities = 86/392 (21%), Positives = 152/392 (38%), Gaps = 73/392 (18%)
Query: 155 VPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSL---LYRFNQKLMSTLKDVISLKFKS 211
VP+ +N GK G+ V + +D+ D G +SL L R N + +++
Sbjct: 780 VPMRFN--GKSGVEVRL-----PNDLEDLKGYTSLSLFLQRPNSRENGGTENMF------ 826
Query: 212 MQGDGVLFHGEGQRG-DHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWH 270
V++ G D+I + + G+L NLGD +A L + +L
Sbjct: 827 -----VMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQ-------VDQILTKSETK 874
Query: 271 SVLIERVGKQ-------VNFTVDKHTQHFRTKGETD--------ALDIDYE---LSFGGI 312
+++RV Q +N+T + T G D L++D E GG
Sbjct: 875 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 934
Query: 313 PVPGK-PGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPI--- 368
P K P + GCIE +D +Y TF+ + ++ P
Sbjct: 935 PPDFKLPSRLSFPPYKGCIE---------LDDLNENVLSLYNFKKTFNLNTTEVEPCRRR 985
Query: 369 ------TFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEG 422
+ +G Y +P P + +T GLL E G + L++E
Sbjct: 986 KEESDKNYFEGTG-YARVPTQPHAPIPTFGQTIQTTVDRGLLFFAE--NGDRFISLNIED 1042
Query: 423 GILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQI 482
G L + + +E E G +N+G HS+ I + + + ++ + D ++
Sbjct: 1043 GKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDG---EV 1099
Query: 483 YSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMR 514
+ ++YY GG P + + ++ AF+GCM+
Sbjct: 1100 FDFSTYYLGGIPIAIRERFNIS-TPAFRGCMK 1130
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 40/156 (25%)
Query: 202 KDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLG 261
K V S++ +S+ G +L H Q G H+ + L+ G++ ++ G + S T
Sbjct: 1572 KLVFSIRPRSLTG--ILIHIGSQPGKHLCVYLEAGKVTASMDSG-----AGGTSTSVTPK 1624
Query: 262 SLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVP------ 315
L D WHSV + T+ +H H LD D + G IP P
Sbjct: 1625 QSLCDGQWHSVAV---------TIKQHILHLE-------LDTDSSYTAGQIPFPPASTQE 1668
Query: 316 -----GKPGTFLK------KNFHGCIENLYYNGVNI 340
G P K+F GC+ N++ N + +
Sbjct: 1669 PLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPV 1704
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 15/138 (10%)
Query: 809 AEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSL 868
++F+ D+ +TT+ G+ F+ L +S + FA+ G +L ++S
Sbjct: 1401 SQFAVDM----QTTSSRGLVFHTGTKNSFMALYLSK-GRLVFAL--GTDGKKLRIKSKEK 1453
Query: 869 LNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQ----- 923
ND +WH V + ++ L VD L RE S G+ + + + +++G S +
Sbjct: 1454 CNDGKWHTVVFGHDGEKGRLVVDGL--RAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 1511
Query: 924 -KGFLGCIRSLHLNGQKM 940
F+GC+++ L+ + +
Sbjct: 1512 TNSFVGCLKNFQLDSKPL 1529
Score = 36.6 bits (83), Expect = 0.16
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 847 EITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHF 906
++T ++D G G V L D QWH V +K+ L ++ S+ +
Sbjct: 1605 KVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAV--TIKQHILHLELDTDSSYTAGQIPFP 1662
Query: 907 RLQLNSQLFVGGTSSRQ--------KGFLGCIRSLHLNGQKMDLEERAKVTSGVR-PGCP 957
L +GG + K F GC+R++H+N + + E +V V GCP
Sbjct: 1663 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1722
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,780,801
Number of Sequences: 37866
Number of extensions: 2455175
Number of successful extensions: 7447
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 5984
Number of HSP's gapped (non-prelim): 1062
length of query: 1306
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1192
effective length of database: 13,930,794
effective search space: 16605506448
effective search space used: 16605506448
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.