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Search of human proteins with 18390331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
(751 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens] 1504 0.0
gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo s... 382 e-106
gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo s... 352 9e-97
gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo s... 268 2e-71
gi|157426893 GUF1 GTPase homolog [Homo sapiens] 103 4e-22
gi|4503483 eukaryotic translation elongation factor 2 [Homo sapi... 102 1e-21
gi|94966754 elongation factor Tu GTP binding domain containing 1... 93 8e-19
gi|239756373 PREDICTED: similar to elongation factor Tu GTP bind... 76 1e-13
gi|239750897 PREDICTED: similar to elongation factor Tu GTP bind... 76 1e-13
gi|239745282 PREDICTED: similar to elongation factor Tu GTP bind... 76 1e-13
gi|217272894 elongation factor Tu GTP binding domain containing ... 68 4e-11
gi|217272892 elongation factor Tu GTP binding domain containing ... 68 4e-11
gi|94966752 elongation factor Tu GTP binding domain containing 1... 64 7e-10
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform... 58 4e-08
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1... 58 4e-08
gi|239757543 PREDICTED: similar to eukaryotic translation elonga... 57 5e-08
gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [H... 57 5e-08
gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [H... 57 6e-08
gi|53729339 mitochondrial translational initiation factor 2 prec... 53 1e-06
gi|53729337 mitochondrial translational initiation factor 2 prec... 53 1e-06
gi|34147630 Tu translation elongation factor, mitochondrial prec... 52 3e-06
gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens] 52 3e-06
gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens] 52 3e-06
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens] 52 3e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 50 8e-06
gi|46094014 peptide chain release factor 3 [Homo sapiens] 50 1e-05
gi|54607086 eukaryotic elongation factor, selenocysteine-tRNA-sp... 34 0.57
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 32 2.8
gi|115298663 SCL/TAL1 interrupting locus isoform 1 [Homo sapiens] 31 3.7
gi|115298661 SCL/TAL1 interrupting locus isoform 2 [Homo sapiens] 31 3.7
>gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
Length = 751
Score = 1504 bits (3893), Expect = 0.0
Identities = 751/751 (100%), Positives = 751/751 (100%)
Query: 1 MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKT 60
MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKT
Sbjct: 1 MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKT 60
Query: 61 TLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIID 120
TLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIID
Sbjct: 61 TLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIID 120
Query: 121 TPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG 180
TPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG
Sbjct: 121 TPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMG 180
Query: 181 SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPA 240
SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPA
Sbjct: 181 SNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPA 240
Query: 241 ELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSA 300
ELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSA
Sbjct: 241 ELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSA 300
Query: 301 LKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKL 360
LKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKL
Sbjct: 301 LKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKL 360
Query: 361 EVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICAL 420
EVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICAL
Sbjct: 361 EVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICAL 420
Query: 421 FGIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTF 480
FGIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTF
Sbjct: 421 FGIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTF 480
Query: 481 KVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHK 540
KVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHK
Sbjct: 481 KVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHK 540
Query: 541 KQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLS 600
KQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLS
Sbjct: 541 KQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLS 600
Query: 601 GHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEF 660
GHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEF
Sbjct: 601 GHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEF 660
Query: 661 QGQVIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRY 720
QGQVIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRY
Sbjct: 661 QGQVIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRY 720
Query: 721 QPCLPSTQEDVINKYLEATGQLPVKKGKAKN 751
QPCLPSTQEDVINKYLEATGQLPVKKGKAKN
Sbjct: 721 QPCLPSTQEDVINKYLEATGQLPVKKGKAKN 751
>gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo
sapiens]
Length = 779
Score = 382 bits (981), Expect = e-106
Identities = 257/731 (35%), Positives = 368/731 (50%), Gaps = 60/731 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGIT 101
P KIRNIGI AHID+GKTT TER+LYY+G + +V D V D M ER+RGIT
Sbjct: 66 PIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGD---TVTDFMAQERERGIT 122
Query: 102 IQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQ 161
IQSAA WK +N+IDTPGHVDFT+EVER LRVLDGAV V A GV+ QT+TV RQ
Sbjct: 123 IQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQ 182
Query: 162 MKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEER 221
++N+P + F+NK+D+ G++ A++ +R KL +Q+P+G FKG+VD++ +
Sbjct: 183 ADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKE 242
Query: 222 AIYF-----DG-DFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEE---- 271
+ + DG DF + EL T+ R LIE VA+ D++ ++ LEE
Sbjct: 243 KLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSEN 302
Query: 272 -KIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILN 330
+ L+ AI R TL ++ PV GSALKNKG+QPLLDAV YLP+P E +NY L
Sbjct: 303 FDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEE-RNYEFLQ 361
Query: 331 KEDDSKEKTKILMNSSRDNSHPFVGLAFK-LEVGRFGQLTYVRSYQGELKKGDTIYNTRT 389
D LAFK L + G L ++R Y G +K I+N
Sbjct: 362 WYKDD-----------------LCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNING 404
Query: 390 RKKVRLQRLARMHADMMEDVEEVYAGDICALFGI-DCASGDTFTDKANSGLS-------- 440
R+ RL AD ++ + AG+I G+ A+GDT +S L+
Sbjct: 405 NCTERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAERE 464
Query: 441 ---------------MESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFD 485
+ + +P+PV ++P + + + REDP+ KV D
Sbjct: 465 GEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLD 524
Query: 486 TENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGG 545
++ +TV+ GMGELH+EI R++REYG G +VA+RETI V T + G
Sbjct: 525 PDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGD 584
Query: 546 AGQYGKVIGVLEPLDPEDYTK-LEFS-DETFGSNIPKQFVPAVEKGFLDACEKGPLSGHK 603
V P++ +EF E+ + K A+E G AC +GPL G
Sbjct: 585 KRHLVTVEVEARPIETSSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSP 644
Query: 604 LSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEFQGQ 663
+ + L H S + +++AL A +LEP+M +EV ++
Sbjct: 645 IQDVAITLHSLTIHPGTSTTM-ISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSP 703
Query: 664 VIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPC 723
V+A + +R G I +D + VPL ++ GYST LR+ T G + +E S YQ
Sbjct: 704 VLADLAQRRGNIQEIQTRQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAM 763
Query: 724 LPSTQEDVINK 734
P Q ++N+
Sbjct: 764 NPQDQNTLLNR 774
>gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo
sapiens]
Length = 732
Score = 352 bits (902), Expect = 9e-97
Identities = 240/706 (33%), Positives = 351/706 (49%), Gaps = 57/706 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGIT 101
P KIRNIGI AHID+GKTT TER+LYY+G + +V D V D M ER+RGIT
Sbjct: 66 PIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGD---TVTDFMAQERERGIT 122
Query: 102 IQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQ 161
IQSAA WK +N+IDTPGHVDFT+EVER LRVLDGAV V A GV+ QT+TV RQ
Sbjct: 123 IQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQ 182
Query: 162 MKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEER 221
++N+P + F+NK+D+ G++ A++ +R KL +Q+P+G FKG+VD++ +
Sbjct: 183 ADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKE 242
Query: 222 AIYF-----DG-DFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEE---- 271
+ + DG DF + EL T+ R LIE VA+ D++ ++ LEE
Sbjct: 243 KLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSEN 302
Query: 272 -KIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILN 330
+ L+ AI R TL ++ PV GSALKNKG+QPLLDAV YLP+P E +NY L
Sbjct: 303 FDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEE-RNYEFLE 361
Query: 331 KEDDSKEKTKILMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRTR 390
+ +++L+ PF ++ G + + GDTI ++++
Sbjct: 362 R------ISRLLL--------PFADQHVEIPSLTAGNIALTVGLK-HTATGDTIVSSKSS 406
Query: 391 KKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVPDPV 450
+R R E L + + +P+PV
Sbjct: 407 ALAAARRAEREGEKKHRQNNEA------------------------ERLLLAGVEIPEPV 442
Query: 451 ISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLER 510
++P + + + REDP+ KV D ++ +TV+ GMGELH+EI R++R
Sbjct: 443 FFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKR 502
Query: 511 EYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPEDYTK-LEF 569
EYG G +VA+RETI V T + G V P++ +EF
Sbjct: 503 EYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIETSSVMPVIEF 562
Query: 570 S-DETFGSNIPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIR 628
E+ + K A+E G AC +GPL G + + L H S +
Sbjct: 563 EYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPGTSTTM-ISA 621
Query: 629 AGEGALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLY 688
+++AL A +LEP+M +EV ++ V+A + +R G I +D +
Sbjct: 622 CVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQTRQDNKVVI 681
Query: 689 ADVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINK 734
VPL ++ GYST LR+ T G + +E S YQ P Q ++N+
Sbjct: 682 GFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNR 727
>gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo
sapiens]
Length = 513
Score = 268 bits (684), Expect = 2e-71
Identities = 170/412 (41%), Positives = 230/412 (55%), Gaps = 34/412 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGIT 101
P KIRNIGI AHID+GKTT TER+LYY+G + +V D V D M ER+RGIT
Sbjct: 66 PIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGD---TVTDFMAQERERGIT 122
Query: 102 IQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQ 161
IQSAA WK +N+IDTPGHVDFT+EVER LRVLDGAV V A GV+ QT+TV RQ
Sbjct: 123 IQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQ 182
Query: 162 MKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEER 221
++N+P + F+NK+D+ G++ A++ +R KL +Q+P+G FKG+VD++ +
Sbjct: 183 ADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKE 242
Query: 222 AIYF-----DG-DFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEE---- 271
+ + DG DF + EL T+ R LIE VA+ D++ ++ LEE
Sbjct: 243 KLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSEN 302
Query: 272 -KIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILN 330
+ L+ AI R TL ++ PV GSALKNKG+QPLLDAV YLP+P E +NY L
Sbjct: 303 FDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEE-RNYEFLQ 361
Query: 331 KEDDSKEKTKILMNSSRDNSHPFVGLAFK-LEVGRFGQLTYVRSYQGELKKGDTIYNTRT 389
D LAFK L + G L ++R Y G +K I+N
Sbjct: 362 WYKDD-----------------LCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNING 404
Query: 390 RKKVRLQRLARMHADMMEDVEEVYAGDICALFGI-DCASGDTFTDKANSGLS 440
R+ RL AD ++ + AG+I G+ A+GDT +S L+
Sbjct: 405 NCTERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALA 456
>gi|157426893 GUF1 GTPase homolog [Homo sapiens]
Length = 669
Score = 103 bits (258), Expect = 4e-22
Identities = 83/257 (32%), Positives = 122/257 (47%), Gaps = 36/257 (14%)
Query: 2 RLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVI---------PNEKIRNIGIS 52
R GAA + A G AP +LG + +W R SS P E IRN I
Sbjct: 18 RATGAALLVAPGPRSAP-TLGAAPE--SWATDRLYSSAEFKEKLDMSRFPVENIRNFSIV 74
Query: 53 AHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMW- 111
AH+D GK+TL +R+L TG I K K V+D +++ER+RGIT+++ +
Sbjct: 75 AHVDHGKSTLADRLLELTGTIDKTKNNK------QVLDKLQVERERGITVKAQTASLFYN 128
Query: 112 ---KDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVP 168
K +N+IDTPGHVDF+ EV R+L G +LV+ A G+Q QT+ +
Sbjct: 129 CEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLS 188
Query: 169 FLTFINKLDRMGSNPARALQQMRSKLN-HNAAFMQIPMGLEGNFKGIVDLIEE------- 220
+ INK+D ++P R Q+ + + ++I L N + ++ I E
Sbjct: 189 VIPVINKIDLKNADPERVENQIEKVFDIPSDECIKISAKLGTNVESVLQAIIERIPPPKV 248
Query: 221 ------RAIYFDGDFGQ 231
RA+ FD F Q
Sbjct: 249 HRKNPLRALVFDSTFDQ 265
Score = 53.1 bits (126), Expect = 9e-07
Identities = 40/190 (21%), Positives = 80/190 (42%), Gaps = 10/190 (5%)
Query: 351 HPFVGLAFKLEVGRF-GQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDV 409
+P L F ++ G + V + G + KGD I + T+K + + ++ + +
Sbjct: 252 NPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNE-QPT 310
Query: 410 EEVYAGDICALFG-----IDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLE 464
++YAG + L + GDT + P++ M P ++++
Sbjct: 311 HKLYAGQVGYLIAGMKDVTEAQIGDTLCLHKQPVEPLPGFKSAKPMVFAGMYPLDQSEYN 370
Query: 465 KFSKGIGRFTREDPTFKVYFDTE---NKETVISGMGELHLEIYAQRLEREYGCPCITGKP 521
I + T D + V+ D+ + +G LH+E++ QRLE+EY I P
Sbjct: 371 NLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTP 430
Query: 522 KVAFRETITA 531
V ++ +++
Sbjct: 431 TVPYKAVLSS 440
>gi|4503483 eukaryotic translation elongation factor 2 [Homo
sapiens]
Length = 858
Score = 102 bits (255), Expect = 1e-21
Identities = 125/528 (23%), Positives = 208/528 (39%), Gaps = 84/528 (15%)
Query: 297 LGSALKNKGVQPLLDAVLE---------------YLPNPSEVQNYAILNKEDDSKEKTKI 341
L S K+K +PLL AV+ +LP+P Q Y + +
Sbjct: 323 LDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAA 382
Query: 342 LMNSSRDNSHPFVGLAFKL----EVGRFGQLTYVRSYQGELKKGDTIY----NTRTRKKV 393
+ S D P + K+ + GRF + R + G + G + N KK
Sbjct: 383 MGIKSCDPKGPLMMYISKMVPTSDKGRF--YAFGRVFSGLVSTGLKVRIMGPNYTPGKKE 440
Query: 394 RL-----QRLARMHADMMEDVEEVYAGDICALFGID-----CASGDTFTDKANSGLSMES 443
L QR M +E +E+V G+I L G+D + TF N + S
Sbjct: 441 DLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFS 500
Query: 444 IHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEI 503
+ PV+ +A++ N DL K +G+ R + DP + + E+ E +I+G GELHLEI
Sbjct: 501 V---SPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIE-ESGEHIIAGAGELHLEI 556
Query: 504 YAQRLEREYGC-PCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKV----IGVLEP 558
+ LE ++ C P P V++RET++ K + Y K G+ E
Sbjct: 557 CLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAED 616
Query: 559 LDPEDYTKLE-----------------------------------FSDETFGSNIPKQFV 583
+D + + + +D T G +
Sbjct: 617 IDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIK 676
Query: 584 PAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHH--MVDSNEISFIRAGEGALKQALANA 641
+V GF A ++G L + G+RF + D H + I L ++ A
Sbjct: 677 DSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTA 736
Query: 642 TLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGV--EDYFTLYADVPLNDMFGY 699
++EPI VE+ P + G + +NR+ G + + V F + A +P+N+ FG+
Sbjct: 737 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 796
Query: 700 STELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEATGQLPVKKG 747
+ +LRS T G+ + +Q LP D ++ + + +KG
Sbjct: 797 TADLRSNTGGQAFPQCVFDHWQ-ILPGDPFDNSSRPSQVVAETRKRKG 843
Score = 88.2 bits (217), Expect = 3e-17
Identities = 58/149 (38%), Positives = 84/149 (56%), Gaps = 21/149 (14%)
Query: 46 IRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
IRN+ + AH+D GK+TLT+ ++ G IA + G D+ + E++R ITI+S
Sbjct: 19 IRNMSVIAHVDHGKSTLTDSLVCKAGIIAS-----ARAGETRFTDTRKDEQERCITIKST 73
Query: 106 ATYTMWK----DVN------------INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVG 149
A ++ D+N IN+ID+PGHVDF+ EV ALRV DGA++V+ V
Sbjct: 74 AISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVS 133
Query: 150 GVQCQTMTVNRQMKRYNVPFLTFINKLDR 178
GV QT TV RQ + + +NK+DR
Sbjct: 134 GVCVQTETVLRQAIAERIKPVLMMNKMDR 162
>gi|94966754 elongation factor Tu GTP binding domain containing 1
isoform 1 [Homo sapiens]
Length = 1120
Score = 93.2 bits (230), Expect = 8e-19
Identities = 59/138 (42%), Positives = 83/138 (60%), Gaps = 9/138 (6%)
Query: 46 IRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
IRNI + AH+D GKTTL + ++ G I+ K + MDS E E+ RGIT++S+
Sbjct: 19 IRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLR-----YMDSREDEQIRGITMKSS 73
Query: 106 ATYTMWKDVN----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQ 161
A + N IN+ID+PGHVDF+ EV A+R+ DG ++V+ AV GV QT V RQ
Sbjct: 74 AISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQ 133
Query: 162 MKRYNVPFLTFINKLDRM 179
N+ + INK+DR+
Sbjct: 134 AWLENIRPVLVINKIDRL 151
Score = 47.4 bits (111), Expect = 5e-05
Identities = 38/155 (24%), Positives = 75/155 (48%), Gaps = 14/155 (9%)
Query: 395 LQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESI--HVP----- 447
L+ L + +E +EEV G++ + G+ F K+ + S+ S +P
Sbjct: 560 LENLYLLMGRELEYLEEVPPGNVLGIGGLQ-----DFVLKSATLCSLPSCPPFIPLNFEA 614
Query: 448 DPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQR 507
P++ +A++P + +++ + KG+ + DP ++ E E V+ GE+HL+
Sbjct: 615 TPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQ-ETGEHVLVTAGEVHLQRCLDD 673
Query: 508 LEREYGCPCIT-GKPKVAFRETITAPVPFDFTHKK 541
L+ + I+ +P + FRETIT P D +++
Sbjct: 674 LKERFAKIHISVSEPIIPFRETITKPPKVDMVNEE 708
Score = 38.5 bits (88), Expect = 0.023
Identities = 24/109 (22%), Positives = 56/109 (51%), Gaps = 8/109 (7%)
Query: 633 ALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVE--DYFTLYAD 690
A + AL ++ + +++A + G+V A +++R G + ++ E D F + A
Sbjct: 968 ACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAV 1027
Query: 691 VPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPC------LPSTQEDVIN 733
+P+ + FG++ E+R T G + +S ++ +P+T+E+ ++
Sbjct: 1028 LPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLH 1076
>gi|239756373 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/110 (42%), Positives = 69/110 (62%), Gaps = 9/110 (8%)
Query: 46 IRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
IRNI + AH+D GKTTL + ++ G I+ + GK MDS E E+ RGIT++S+
Sbjct: 150 IRNICVLAHVDRGKTTLADCLISSNGIISS--HLAGKL---RYMDSREDEQIRGITMKSS 204
Query: 106 ATYTMWKDVN----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGV 151
A + N IN+ID+PGH+DF+ +V A+R+ DG ++V+ AV GV
Sbjct: 205 AISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|239750897 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/110 (42%), Positives = 69/110 (62%), Gaps = 9/110 (8%)
Query: 46 IRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
IRNI + AH+D GKTTL + ++ G I+ + GK MDS E E+ RGIT++S+
Sbjct: 150 IRNICVLAHVDRGKTTLADCLISSNGIISS--HLAGKL---RYMDSREDEQIRGITMKSS 204
Query: 106 ATYTMWKDVN----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGV 151
A + N IN+ID+PGH+DF+ +V A+R+ DG ++V+ AV GV
Sbjct: 205 AISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|239745282 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/110 (42%), Positives = 69/110 (62%), Gaps = 9/110 (8%)
Query: 46 IRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
IRNI + AH+D GKTTL + ++ G I+ + GK MDS E E+ RGIT++S+
Sbjct: 150 IRNICVLAHVDRGKTTLADCLISSNGIISS--HLAGKL---RYMDSREDEQIRGITMKSS 204
Query: 106 ATYTMWKDVN----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGV 151
A + N IN+ID+PGH+DF+ +V A+R+ DG ++V+ AV GV
Sbjct: 205 AISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|217272894 elongation factor Tu GTP binding domain containing 2
isoform b [Homo sapiens]
Length = 937
Score = 67.8 bits (164), Expect = 4e-11
Identities = 90/370 (24%), Positives = 143/370 (38%), Gaps = 66/370 (17%)
Query: 398 LARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVP-----DPVIS 452
+AR H + V V AG+ + G+D T T G I P VI
Sbjct: 499 VARYHIE----VNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIK 554
Query: 453 IAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREY 512
IA++P N ++L K G+ + + P+ + E+ E VI G GEL+L+ L + Y
Sbjct: 555 IAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVE-ESGEHVILGTGELYLDCVMHDLRKMY 613
Query: 513 GCPCI-TGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDP---EDY---- 564
I P V F ET+ K + + K+ + EPL+ ED
Sbjct: 614 SEIDIKVADPVVTFCETVVETSSL----KCFAETPNKKNKITMIAEPLEKGLAEDIENEV 669
Query: 565 ---------------TKLEFS---------------------DETFGSNIPKQFVPAVE- 587
TK ++ D+T S + K + +V+
Sbjct: 670 VQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKD 729
Query: 588 ---KGFLDACEKGPLSGHKLSGLRFVLQDG--AHHMVDSNEISFIRAGEGALKQALANAT 642
+GF +GPL + ++F + D A + I + A AT
Sbjct: 730 SIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMAT 789
Query: 643 LCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGV--EDYFTLYADVPLNDMFGYS 700
++EP VEV AP + V + RR G +T + +T+ A +P D FG+
Sbjct: 790 PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 849
Query: 701 TELRSCTEGK 710
T+LR+ T+G+
Sbjct: 850 TDLRTHTQGQ 859
Score = 66.6 bits (161), Expect = 8e-11
Identities = 44/142 (30%), Positives = 69/142 (48%), Gaps = 9/142 (6%)
Query: 43 NEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITI 102
+E IRN+ + H+ GKT + ++ T + K D D + E++RG+ I
Sbjct: 91 SELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIR----KRYDQDLCYTDILFTEQERGVGI 146
Query: 103 QSAATYTMWKDVN-----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMT 157
+S + D NI+DTPGHV+F+ EV LR+ DG VL + A GV T
Sbjct: 147 KSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTER 206
Query: 158 VNRQMKRYNVPFLTFINKLDRM 179
+ + + + INK+DR+
Sbjct: 207 LIKHAVQERLAVTVCINKIDRL 228
>gi|217272892 elongation factor Tu GTP binding domain containing 2
isoform a [Homo sapiens]
Length = 972
Score = 67.8 bits (164), Expect = 4e-11
Identities = 90/370 (24%), Positives = 143/370 (38%), Gaps = 66/370 (17%)
Query: 398 LARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVP-----DPVIS 452
+AR H + V V AG+ + G+D T T G I P VI
Sbjct: 534 VARYHIE----VNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIK 589
Query: 453 IAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREY 512
IA++P N ++L K G+ + + P+ + E+ E VI G GEL+L+ L + Y
Sbjct: 590 IAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVE-ESGEHVILGTGELYLDCVMHDLRKMY 648
Query: 513 GCPCI-TGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDP---EDY---- 564
I P V F ET+ K + + K+ + EPL+ ED
Sbjct: 649 SEIDIKVADPVVTFCETVVETSSL----KCFAETPNKKNKITMIAEPLEKGLAEDIENEV 704
Query: 565 ---------------TKLEFS---------------------DETFGSNIPKQFVPAVE- 587
TK ++ D+T S + K + +V+
Sbjct: 705 VQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKD 764
Query: 588 ---KGFLDACEKGPLSGHKLSGLRFVLQDG--AHHMVDSNEISFIRAGEGALKQALANAT 642
+GF +GPL + ++F + D A + I + A AT
Sbjct: 765 SIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMAT 824
Query: 643 LCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGV--EDYFTLYADVPLNDMFGYS 700
++EP VEV AP + V + RR G +T + +T+ A +P D FG+
Sbjct: 825 PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 884
Query: 701 TELRSCTEGK 710
T+LR+ T+G+
Sbjct: 885 TDLRTHTQGQ 894
Score = 66.6 bits (161), Expect = 8e-11
Identities = 44/142 (30%), Positives = 69/142 (48%), Gaps = 9/142 (6%)
Query: 43 NEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITI 102
+E IRN+ + H+ GKT + ++ T + K D D + E++RG+ I
Sbjct: 126 SELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIR----KRYDQDLCYTDILFTEQERGVGI 181
Query: 103 QSAATYTMWKDVN-----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMT 157
+S + D NI+DTPGHV+F+ EV LR+ DG VL + A GV T
Sbjct: 182 KSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTER 241
Query: 158 VNRQMKRYNVPFLTFINKLDRM 179
+ + + + INK+DR+
Sbjct: 242 LIKHAVQERLAVTVCINKIDRL 263
>gi|94966752 elongation factor Tu GTP binding domain containing 1
isoform 2 [Homo sapiens]
Length = 1069
Score = 63.5 bits (153), Expect = 7e-10
Identities = 32/64 (50%), Positives = 44/64 (68%)
Query: 116 INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINK 175
IN+ID+PGHVDF+ EV A+R+ DG ++V+ AV GV QT V RQ N+ + INK
Sbjct: 37 INLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINK 96
Query: 176 LDRM 179
+DR+
Sbjct: 97 IDRL 100
Score = 47.4 bits (111), Expect = 5e-05
Identities = 38/155 (24%), Positives = 75/155 (48%), Gaps = 14/155 (9%)
Query: 395 LQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESI--HVP----- 447
L+ L + +E +EEV G++ + G+ F K+ + S+ S +P
Sbjct: 509 LENLYLLMGRELEYLEEVPPGNVLGIGGLQ-----DFVLKSATLCSLPSCPPFIPLNFEA 563
Query: 448 DPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQR 507
P++ +A++P + +++ + KG+ + DP ++ E E V+ GE+HL+
Sbjct: 564 TPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQ-ETGEHVLVTAGEVHLQRCLDD 622
Query: 508 LEREYGCPCIT-GKPKVAFRETITAPVPFDFTHKK 541
L+ + I+ +P + FRETIT P D +++
Sbjct: 623 LKERFAKIHISVSEPIIPFRETITKPPKVDMVNEE 657
Score = 38.5 bits (88), Expect = 0.023
Identities = 24/109 (22%), Positives = 56/109 (51%), Gaps = 8/109 (7%)
Query: 633 ALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVE--DYFTLYAD 690
A + AL ++ + +++A + G+V A +++R G + ++ E D F + A
Sbjct: 917 ACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAV 976
Query: 691 VPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPC------LPSTQEDVIN 733
+P+ + FG++ E+R T G + +S ++ +P+T+E+ ++
Sbjct: 977 LPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLH 1025
>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
[Homo sapiens]
Length = 642
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/206 (26%), Positives = 87/206 (42%), Gaps = 25/206 (12%)
Query: 22 GWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAK--MHEV 79
G R+Q++ KA G +++ N+ + H+D+GK+TL +LY G I K MH+
Sbjct: 197 GKLRQQIDVKAELEKRQG---GKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKY 253
Query: 80 --------KGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEV 131
K V+D ER+RG+T+ T I ++D PGH DF +
Sbjct: 254 EQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNM 313
Query: 132 ERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNV--------PFLTFINKLDRMGSNP 183
D AVLV+ A G Q + + + +NK+D++
Sbjct: 314 ITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQ 373
Query: 184 ARALQQMRSKLNH---NAAFMQIPMG 206
R Q++ KL H A F + +G
Sbjct: 374 ER-FQEITGKLGHFLKQAGFKESDVG 398
>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
[Homo sapiens]
Length = 684
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/206 (26%), Positives = 87/206 (42%), Gaps = 25/206 (12%)
Query: 22 GWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAK--MHEV 79
G R+Q++ KA G +++ N+ + H+D+GK+TL +LY G I K MH+
Sbjct: 239 GKLRQQIDVKAELEKRQG---GKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKY 295
Query: 80 --------KGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEV 131
K V+D ER+RG+T+ T I ++D PGH DF +
Sbjct: 296 EQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNM 355
Query: 132 ERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNV--------PFLTFINKLDRMGSNP 183
D AVLV+ A G Q + + + +NK+D++
Sbjct: 356 ITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQ 415
Query: 184 ARALQQMRSKLNH---NAAFMQIPMG 206
R Q++ KL H A F + +G
Sbjct: 416 ER-FQEITGKLGHFLKQAGFKESDVG 440
>gi|239757543 PREDICTED: similar to eukaryotic translation
elongation factor 1 alpha 2 [Homo sapiens]
Length = 444
Score = 57.4 bits (137), Expect = 5e-08
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 26/152 (17%)
Query: 48 NIGISAHIDSGKTTLTERVLYYTG-----RIAKMHEVKGKDGVGA-----VMDSMELERQ 97
NI + H+DSGK+T T ++Y G I K + + G G+ V+D ++ ER+
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 98 RGITIQSAATYTMWK----DVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCA-VG--- 149
RGITI ++WK I IID PGH DF + D AVL++ A VG
Sbjct: 69 RGITID----ISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFE 124
Query: 150 -GVQCQTMTVNRQMKRYNV---PFLTFINKLD 177
G+ T + Y + + +NK+D
Sbjct: 125 AGISKNGQTREHALLAYTLGVKQLIVGVNKMD 156
>gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [Homo
sapiens]
Length = 463
Score = 57.4 bits (137), Expect = 5e-08
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 26/152 (17%)
Query: 48 NIGISAHIDSGKTTLTERVLYYTG-----RIAKMHEVKGKDGVGA-----VMDSMELERQ 97
NI + H+DSGK+T T ++Y G I K + + G G+ V+D ++ ER+
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 98 RGITIQSAATYTMWK----DVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCA-VG--- 149
RGITI ++WK I IID PGH DF + D AVL++ A VG
Sbjct: 69 RGITID----ISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFE 124
Query: 150 -GVQCQTMTVNRQMKRYNV---PFLTFINKLD 177
G+ T + Y + + +NK+D
Sbjct: 125 AGISKNGQTREHALLAYTLGVKQLIVGVNKMD 156
>gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [Homo
sapiens]
Length = 462
Score = 57.0 bits (136), Expect = 6e-08
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 48 NIGISAHIDSGKTTLTERVLYYTG-----RIAKMHEVKGKDGVGA-----VMDSMELERQ 97
NI + H+DSGK+T T ++Y G I K + + G G+ V+D ++ ER+
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 98 RGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCA-VG----GVQ 152
RGITI + + IID PGH DF + D AVL++ A VG G+
Sbjct: 69 RGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 153 CQTMTVNRQMKRYNV---PFLTFINKLD 177
T + Y + + +NK+D
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMD 156
>gi|53729339 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 20/142 (14%)
Query: 49 IGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATY 108
+ I H+D GKTTL ++ + ++A + +GA + S+ +
Sbjct: 183 VTIMGHVDHGKTTLLDK--FRKTQVAAVETGGITQHIGAFLVSLPSGEK----------- 229
Query: 109 TMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVP 168
I +DTPGH F+ R +V D VLV+ A GV QT+ + K VP
Sbjct: 230 -------ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP 282
Query: 169 FLTFINKLDRMGSNPARALQQM 190
+ +NK D+ ++P + +++
Sbjct: 283 IILAVNKCDKAEADPEKVKKEL 304
>gi|53729337 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 20/142 (14%)
Query: 49 IGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATY 108
+ I H+D GKTTL ++ + ++A + +GA + S+ +
Sbjct: 183 VTIMGHVDHGKTTLLDK--FRKTQVAAVETGGITQHIGAFLVSLPSGEK----------- 229
Query: 109 TMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVP 168
I +DTPGH F+ R +V D VLV+ A GV QT+ + K VP
Sbjct: 230 -------ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP 282
Query: 169 FLTFINKLDRMGSNPARALQQM 190
+ +NK D+ ++P + +++
Sbjct: 283 IILAVNKCDKAEADPEKVKKEL 304
>gi|34147630 Tu translation elongation factor, mitochondrial
precursor [Homo sapiens]
Length = 455
Score = 51.6 bits (122), Expect = 3e-06
Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 14/135 (10%)
Query: 48 NIGISAHIDSGKTTLTERV--LYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSA 105
N+G H+D GKTTLT + + G AK + + +D+ ER RGITI +A
Sbjct: 62 NVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEE-------IDNAPEERARGITINAA 114
Query: 106 ATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQT---MTVNRQM 162
+ D PGH D+ + LDG +LV+ A G QT + + RQ+
Sbjct: 115 HVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQI 174
Query: 163 KRYNVPFLTFINKLD 177
+V + ++NK D
Sbjct: 175 GVEHV--VVYVNKAD 187
>gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]
Length = 499
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKM------HEVKGKDG----VGAVMDS 91
P ++ N+ H+D+GK+T+ +++Y TG + K E K K+ + +D+
Sbjct: 70 PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDT 129
Query: 92 MELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGG 150
+ ER +G T++ Y + + I+D PGH F + D AVLV+ A G
Sbjct: 130 NQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKG 188
>gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]
Length = 636
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKM------HEVKGKDG----VGAVMDS 91
P ++ N+ H+D+GK+T+ +++Y TG + K E K K+ + +D+
Sbjct: 207 PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDT 266
Query: 92 MELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGG 150
+ ER +G T++ Y + + I+D PGH F + D AVLV+ A G
Sbjct: 267 NQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKG 325
>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
Length = 637
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKM------HEVKGKDG----VGAVMDS 91
P ++ N+ H+D+GK+T+ +++Y TG + K E K K+ + +D+
Sbjct: 208 PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDT 267
Query: 92 MELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGG 150
+ ER +G T++ Y + + I+D PGH F + D AVLV+ A G
Sbjct: 268 NQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKG 326
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 50.1 bits (118), Expect = 8e-06
Identities = 41/153 (26%), Positives = 74/153 (48%), Gaps = 15/153 (9%)
Query: 34 RWSSSGVIPNEKIRN--IGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDG-----VG 86
R S + EK+R I + H+D+GKT + +++ + H G+ G +G
Sbjct: 617 RLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRH-------THVQDGEAGGITQQIG 669
Query: 87 AVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLC 146
A +E ++ I++ + + + IIDTPGH F+ R + D A+LV+
Sbjct: 670 ATNVPLEAINEQTKMIKNFDRENV-RIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVD 728
Query: 147 AVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRM 179
+ G++ QT+ +K PF+ +NK+DR+
Sbjct: 729 IMHGLEPQTIESINLLKSKKCPFIVALNKIDRL 761
>gi|46094014 peptide chain release factor 3 [Homo sapiens]
Length = 628
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKM------HEVKGKDG----VGAVMDS 91
P ++ N+ H+D+GK+T+ ++++ TG + K E K K+ + +D+
Sbjct: 199 PKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDT 258
Query: 92 MELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGG 150
+ ER +G T++ Y + + I+D PGH F + D AVLV+ A G
Sbjct: 259 NQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKG 317
>gi|54607086 eukaryotic elongation factor,
selenocysteine-tRNA-specific [Homo sapiens]
Length = 596
Score = 33.9 bits (76), Expect = 0.57
Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 39/133 (29%)
Query: 48 NIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITI----- 102
N+G+ HIDSGKT L R L T A D R+RGIT+
Sbjct: 9 NVGVLGHIDSGKTALA-RALSTTAST-------------AAFDKQPQSRERGITLDLGFS 54
Query: 103 -----------QSAATYTMWKD---------VNINIIDTPGHVDFTIEVERALRVLDGAV 142
S + + + + ++D PGH + +++D +
Sbjct: 55 CFSVPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMM 114
Query: 143 LVLCAVGGVQCQT 155
LV+ G+Q Q+
Sbjct: 115 LVIDVTKGMQTQS 127
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 31.6 bits (70), Expect = 2.8
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 171 TFINKLDRMGSNPARALQQMRSKLNHNA--AFMQIPMGLEGNFKGIVDLIEERAIYFDGD 228
TF+N RM SN R RS N +A + Q G+ +++ ++ER +Y++G
Sbjct: 418 TFVN---RMKSNHMRG----RSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGL 470
Query: 229 FGQIVRYGEIPAELRAAATDHRQELIECVANSDEQ 263
++ + + L A +HR++L ++ Q
Sbjct: 471 QDKLAQIRDARGALSALREEHREKLRRAAEEAERQ 505
>gi|115298663 SCL/TAL1 interrupting locus isoform 1 [Homo sapiens]
Length = 1288
Score = 31.2 bits (69), Expect = 3.7
Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 422 GIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFK 481
G++C S F + SGLS + + +IA+K N+N L + S DP
Sbjct: 1040 GLNCMS---FANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSL 1096
Query: 482 VYFDTENKETVISGMGELHLEIYAQRLEREYG 513
++ +T+ +S + ++ ++ + YG
Sbjct: 1097 LHINTDRSTVGLSLISPNNMSFATKKYMKRYG 1128
>gi|115298661 SCL/TAL1 interrupting locus isoform 2 [Homo sapiens]
Length = 1287
Score = 31.2 bits (69), Expect = 3.7
Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 422 GIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFK 481
G++C S F + SGLS + + +IA+K N+N L + S DP
Sbjct: 1039 GLNCMS---FANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQNNCDPFSL 1095
Query: 482 VYFDTENKETVISGMGELHLEIYAQRLEREYG 513
++ +T+ +S + ++ ++ + YG
Sbjct: 1096 LHINTDRSTVGLSLISPNNMSFATKKYMKRYG 1127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,624,197
Number of Sequences: 37866
Number of extensions: 1250237
Number of successful extensions: 2673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2570
Number of HSP's gapped (non-prelim): 65
length of query: 751
length of database: 18,247,518
effective HSP length: 110
effective length of query: 641
effective length of database: 14,082,258
effective search space: 9026727378
effective search space used: 9026727378
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.