Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 18105007
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18105007 carbamoylphosphate synthetase 2/aspartate
transcarbamylase/dihydroorotase [Homo sapiens]
(2225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba... 4452 0.0
gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso... 1436 0.0
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor... 1436 0.0
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa... 1045 0.0
gi|38788445 ornithine carbamoyltransferase precursor [Homo sapiens] 96 5e-19
gi|106049528 pyruvate carboxylase precursor [Homo sapiens] 79 6e-14
gi|106049295 pyruvate carboxylase precursor [Homo sapiens] 79 6e-14
gi|106049292 pyruvate carboxylase precursor [Homo sapiens] 79 6e-14
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 69 7e-11
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 69 7e-11
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 69 7e-11
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 69 7e-11
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 69 7e-11
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens] 66 3e-10
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ... 63 4e-09
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide... 63 4e-09
gi|190194363 dihydropyrimidinase-like 4 [Homo sapiens] 57 2e-07
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr... 55 8e-07
gi|19923821 dihydropyrimidinase-like 5 [Homo sapiens] 52 7e-06
gi|4503379 dihydropyrimidinase-like 3 [Homo sapiens] 48 1e-04
gi|4503377 dihydropyrimidinase-like 2 [Homo sapiens] 46 5e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 45 0.001
gi|4503375 dihydropyrimidinase [Homo sapiens] 44 0.001
gi|62422571 collapsin response mediator protein 1 isoform 1 [Hom... 42 0.005
gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo... 42 0.005
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] 42 0.009
gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens] 42 0.009
gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens] 42 0.009
gi|194272172 double homeobox, 4 [Homo sapiens] 42 0.009
gi|194272217 double homeobox, 4-like [Homo sapiens] 42 0.009
>gi|18105007 carbamoylphosphate synthetase 2/aspartate
transcarbamylase/dihydroorotase [Homo sapiens]
Length = 2225
Score = 4452 bits (11547), Expect = 0.0
Identities = 2225/2225 (100%), Positives = 2225/2225 (100%)
Query: 1 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY 60
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
Sbjct: 1 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY 60
Query: 61 GIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD 120
GIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD
Sbjct: 61 GIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD 120
Query: 121 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA 180
TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA
Sbjct: 121 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA 180
Query: 181 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL 240
LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL
Sbjct: 181 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL 240
Query: 241 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE 300
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
Sbjct: 241 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE 300
Query: 301 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA 360
TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA
Sbjct: 301 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA 360
Query: 361 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI 420
TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
Sbjct: 361 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI 420
Query: 421 KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT 480
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
Sbjct: 421 KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT 480
Query: 481 ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ 540
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
Sbjct: 481 ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ 540
Query: 541 AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI 600
AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI
Sbjct: 541 AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI 600
Query: 601 EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG 660
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
Sbjct: 601 EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG 660
Query: 661 IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN 720
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
Sbjct: 661 IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN 720
Query: 721 SVTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
SVTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
Sbjct: 721 SVTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
Query: 781 RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM 840
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM
Sbjct: 781 RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM 840
Query: 841 KRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV 900
KRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV
Sbjct: 841 KRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV 900
Query: 901 KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ 960
KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
Sbjct: 901 KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ 960
Query: 961 QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP 1020
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
Sbjct: 961 QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP 1020
Query: 1021 NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT 1080
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
Sbjct: 1021 NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT 1080
Query: 1081 VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV 1140
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
Sbjct: 1081 VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV 1140
Query: 1141 ASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN 1200
ASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
Sbjct: 1141 ASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN 1200
Query: 1201 LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG 1260
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG
Sbjct: 1201 LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG 1260
Query: 1261 VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG 1320
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
Sbjct: 1261 VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG 1320
Query: 1321 SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI 1380
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
Sbjct: 1321 SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI 1380
Query: 1381 LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL 1440
LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
Sbjct: 1381 LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL 1440
Query: 1441 GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV 1500
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV
Sbjct: 1441 GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV 1500
Query: 1501 CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLN 1560
CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLN
Sbjct: 1501 CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLN 1560
Query: 1561 ETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEE 1620
ETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEE
Sbjct: 1561 ETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEE 1620
Query: 1621 ILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVI 1680
ILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVI
Sbjct: 1621 ILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVI 1680
Query: 1681 DCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF 1740
DCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
Sbjct: 1681 DCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF 1740
Query: 1741 HLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL 1800
HLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
Sbjct: 1741 HLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL 1800
Query: 1801 VPPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASD 1860
VPPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASD
Sbjct: 1801 VPPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASD 1860
Query: 1861 PGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS 1920
PGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
Sbjct: 1861 PGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS 1920
Query: 1921 LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF 1980
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
Sbjct: 1921 LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF 1980
Query: 1981 AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR 2040
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
Sbjct: 1981 AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR 2040
Query: 2041 PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS 2100
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
Sbjct: 2041 PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS 2100
Query: 2101 LRYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEA 2160
LRYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEA
Sbjct: 2101 LRYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEA 2160
Query: 2161 CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT 2220
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
Sbjct: 2161 CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT 2220
Query: 2221 VLGRF 2225
VLGRF
Sbjct: 2221 VLGRF 2225
>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
[Homo sapiens]
Length = 1506
Score = 1436 bits (3717), Expect = 0.0
Identities = 747/1458 (51%), Positives = 1018/1458 (69%), Gaps = 45/1458 (3%)
Query: 2 AALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYG 61
A +VLEDG+ ++G FG S AGEVVF TG+ GYPEA+TDP+YK QIL + P+IGN G
Sbjct: 52 AHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGG 111
Query: 62 IPPDE-MDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD 120
P +DE GL K+ ES+GI V+ L+V + +HW AT++L +WLQ+ +P + GVD
Sbjct: 112 APDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVD 171
Query: 121 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA 180
TR LTK +R++G++LGK+ G + F+DPN + L+ EVS K +V+ G +++A
Sbjct: 172 TRMLTKIIRDKGTMLGKIEFEG---QPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVA 228
Query: 181 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL 240
+DCG+K N IR L +RGAEV +VPW+H EY+G+ ++ GPG+PA ++ + ++L
Sbjct: 229 VDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKIL 288
Query: 241 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE 300
P+FGI G+ + LA GAKTYKM NRG NQP L + + + F+T+QNHG+A++
Sbjct: 289 ESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALD 348
Query: 301 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA 360
++LPA W PLF N ND +NEGI+H S PFF+VQFHPE GP D E LFD F +K+
Sbjct: 349 -NTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKG 407
Query: 361 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI 420
A +T L P + + KVLILGSGGLSIGQAGEFDYSGSQA+
Sbjct: 408 KATT---------ITSVLPKPALVASRVEVS---KVLILGSGGLSIGQAGEFDYSGSQAV 455
Query: 421 KALKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLLTFG 477
KA+KEEN++T+L+NPNIA+VQT++ GL AD VYFLPITP +VT+VI+ E+PDG++L G
Sbjct: 456 KAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMG 515
Query: 478 GQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANS 537
GQTALNCGVEL K GVL YGV+VLGT VE+I TEDR+ F+ ++ EI E +APS A S
Sbjct: 516 GQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVES 575
Query: 538 LEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGW 597
+E A AA+ +GYPV++R+A+ALGGLGSG NRE L L AFA T+Q+LV+KS+ GW
Sbjct: 576 IEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGW 635
Query: 598 KEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQ 657
KEIEYEVVRDA NCVTVCNMEN+D +G+HTG+S+VVAP+QTL++ E+Q+LR+T+I V +
Sbjct: 636 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVR 695
Query: 658 HLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPE 717
HLGIVGECN+Q+AL+P S +Y IIEVNARLSRSSALASKATGYPLA++AAK+ALGIPLPE
Sbjct: 696 HLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPE 755
Query: 718 LRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAF 776
++N V+G T+A FEPS+DY V KIPRWDL +F S++IGS MKSVGEVM IGR+FEE+F
Sbjct: 756 IKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESF 815
Query: 777 QKALRMVDENCVGFDHTVKPVSDM--------ELETPTDKRIFVVAAALWAGYSVDRLYE 828
QKALRM + GF + + EL P+ RI+ +A A+ S+D + +
Sbjct: 816 QKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEK 875
Query: 829 LTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVR 888
LT ID+WFL++M+ I+ + L+ + + + L++AK +GFSDKQI+ + TE R
Sbjct: 876 LTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTR 935
Query: 889 KLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSS 948
+LR + I P VKQIDT+AAE+P+ TNYLY+TY G HD+ F ++VLG G Y IGSS
Sbjct: 936 ELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSS 995
Query: 949 VEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENP 1008
VEFDWCAV I+ LR++G KT++VN NPETVSTD+D CD+LYF+E+S E ++DIY E
Sbjct: 996 VEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEAC 1055
Query: 1009 EGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWREL 1068
G I+S+GGQ+PNN+A+ L++ +++GTSP ID AE+R FS +LD + ++Q W+ +
Sbjct: 1056 GGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAV 1115
Query: 1069 SDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKF 1128
+ L A +F ++V YPC++RPSYVLSG+AMNV +++ ++++FL A VS+EHPVV++KF
Sbjct: 1116 NTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKF 1175
Query: 1129 IQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHA 1188
++ A+E+++DAV DG V + AISEHVE+AGVHSGDATL+ P Q I+ +E++K
Sbjct: 1176 VEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRK 1235
Query: 1189 VGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVE 1248
+ + ++GPFN+Q + K + + VIECN+R SRSFPFVSKTLGVD + +AT+V++GE V+
Sbjct: 1236 IAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVD 1295
Query: 1249 PVGLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKA 1302
L T + V +K P FS+ RL AD +L EM STGEVA FGE A+LKA
Sbjct: 1296 EKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKA 1355
Query: 1303 MLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAV 1362
MLSTGFKIP+K IL+ I + L L + G+ L+A+ T+D+ + V T V
Sbjct: 1356 MLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPV 1414
Query: 1363 DWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADF 1422
W +E G+ P SI + + + + +LVINL + FV Y RR A D
Sbjct: 1415 AWPSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRTAVDS 1465
Query: 1423 SVPLIIDIKCTKLFVEAL 1440
+PL+ + + TKLF EA+
Sbjct: 1466 GIPLLTNFQVTKLFAEAV 1483
>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
[Homo sapiens]
Length = 1500
Score = 1436 bits (3717), Expect = 0.0
Identities = 747/1458 (51%), Positives = 1018/1458 (69%), Gaps = 45/1458 (3%)
Query: 2 AALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYG 61
A +VLEDG+ ++G FG S AGEVVF TG+ GYPEA+TDP+YK QIL + P+IGN G
Sbjct: 46 AHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGG 105
Query: 62 IPPDE-MDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD 120
P +DE GL K+ ES+GI V+ L+V + +HW AT++L +WLQ+ +P + GVD
Sbjct: 106 APDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVD 165
Query: 121 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA 180
TR LTK +R++G++LGK+ G + F+DPN + L+ EVS K +V+ G +++A
Sbjct: 166 TRMLTKIIRDKGTMLGKIEFEG---QPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVA 222
Query: 181 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL 240
+DCG+K N IR L +RGAEV +VPW+H EY+G+ ++ GPG+PA ++ + ++L
Sbjct: 223 VDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKIL 282
Query: 241 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE 300
P+FGI G+ + LA GAKTYKM NRG NQP L + + + F+T+QNHG+A++
Sbjct: 283 ESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALD 342
Query: 301 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA 360
++LPA W PLF N ND +NEGI+H S PFF+VQFHPE GP D E LFD F +K+
Sbjct: 343 -NTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKG 401
Query: 361 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI 420
A +T L P + + KVLILGSGGLSIGQAGEFDYSGSQA+
Sbjct: 402 KATT---------ITSVLPKPALVASRVEVS---KVLILGSGGLSIGQAGEFDYSGSQAV 449
Query: 421 KALKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLLTFG 477
KA+KEEN++T+L+NPNIA+VQT++ GL AD VYFLPITP +VT+VI+ E+PDG++L G
Sbjct: 450 KAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMG 509
Query: 478 GQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANS 537
GQTALNCGVEL K GVL YGV+VLGT VE+I TEDR+ F+ ++ EI E +APS A S
Sbjct: 510 GQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVES 569
Query: 538 LEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGW 597
+E A AA+ +GYPV++R+A+ALGGLGSG NRE L L AFA T+Q+LV+KS+ GW
Sbjct: 570 IEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGW 629
Query: 598 KEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQ 657
KEIEYEVVRDA NCVTVCNMEN+D +G+HTG+S+VVAP+QTL++ E+Q+LR+T+I V +
Sbjct: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVR 689
Query: 658 HLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPE 717
HLGIVGECN+Q+AL+P S +Y IIEVNARLSRSSALASKATGYPLA++AAK+ALGIPLPE
Sbjct: 690 HLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPE 749
Query: 718 LRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAF 776
++N V+G T+A FEPS+DY V KIPRWDL +F S++IGS MKSVGEVM IGR+FEE+F
Sbjct: 750 IKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESF 809
Query: 777 QKALRMVDENCVGFDHTVKPVSDM--------ELETPTDKRIFVVAAALWAGYSVDRLYE 828
QKALRM + GF + + EL P+ RI+ +A A+ S+D + +
Sbjct: 810 QKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEK 869
Query: 829 LTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVR 888
LT ID+WFL++M+ I+ + L+ + + + L++AK +GFSDKQI+ + TE R
Sbjct: 870 LTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTR 929
Query: 889 KLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSS 948
+LR + I P VKQIDT+AAE+P+ TNYLY+TY G HD+ F ++VLG G Y IGSS
Sbjct: 930 ELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSS 989
Query: 949 VEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENP 1008
VEFDWCAV I+ LR++G KT++VN NPETVSTD+D CD+LYF+E+S E ++DIY E
Sbjct: 990 VEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEAC 1049
Query: 1009 EGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWREL 1068
G I+S+GGQ+PNN+A+ L++ +++GTSP ID AE+R FS +LD + ++Q W+ +
Sbjct: 1050 GGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAV 1109
Query: 1069 SDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKF 1128
+ L A +F ++V YPC++RPSYVLSG+AMNV +++ ++++FL A VS+EHPVV++KF
Sbjct: 1110 NTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKF 1169
Query: 1129 IQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHA 1188
++ A+E+++DAV DG V + AISEHVE+AGVHSGDATL+ P Q I+ +E++K
Sbjct: 1170 VEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRK 1229
Query: 1189 VGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVE 1248
+ + ++GPFN+Q + K + + VIECN+R SRSFPFVSKTLGVD + +AT+V++GE V+
Sbjct: 1230 IAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVD 1289
Query: 1249 PVGLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKA 1302
L T + V +K P FS+ RL AD +L EM STGEVA FGE A+LKA
Sbjct: 1290 EKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKA 1349
Query: 1303 MLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAV 1362
MLSTGFKIP+K IL+ I + L L + G+ L+A+ T+D+ + V T V
Sbjct: 1350 MLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPV 1408
Query: 1363 DWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADF 1422
W +E G+ P SI + + + + +LVINL + FV Y RR A D
Sbjct: 1409 AWPSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRTAVDS 1459
Query: 1423 SVPLIIDIKCTKLFVEAL 1440
+PL+ + + TKLF EA+
Sbjct: 1460 GIPLLTNFQVTKLFAEAV 1477
>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
sapiens]
Length = 1049
Score = 1045 bits (2703), Expect = 0.0
Identities = 544/1036 (52%), Positives = 741/1036 (71%), Gaps = 28/1036 (2%)
Query: 423 LKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQ 479
+KEEN++T+L+NPNIA+VQT++ GL AD VYFLPITP +VT+VI+ E+PDG++L GGQ
Sbjct: 1 MKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQ 60
Query: 480 TALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLE 539
TALNCGVEL K GVL YGV+VLGT VE+I TEDR+ F+ ++ EI E +APS A S+E
Sbjct: 61 TALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIE 120
Query: 540 QAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKE 599
A AA+ +GYPV++R+A+ALGGLGSG NRE L L AFA T+Q+LV+KS+ GWKE
Sbjct: 121 DALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKE 180
Query: 600 IEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHL 659
IEYEVVRDA NCVTVCNMEN+D +G+HTG+S+VVAP+QTL++ E+Q+LR+T+I V +HL
Sbjct: 181 IEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHL 240
Query: 660 GIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELR 719
GIVGECN+Q+AL+P S +Y IIEVNARLSRSSALASKATGYPLA++AAK+ALGIPLPE++
Sbjct: 241 GIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIK 300
Query: 720 NSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQK 778
N V+G T+A FEPS+DY V KIPRWDL +F S++IGS MKSVGEVM IGR+FEE+FQK
Sbjct: 301 NVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQK 360
Query: 779 ALRMVDENCVGFDHTVKPVSDM--------ELETPTDKRIFVVAAALWAGYSVDRLYELT 830
ALRM + GF + + EL P+ RI+ +A A+ S+D + +LT
Sbjct: 361 ALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLT 420
Query: 831 RIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKL 890
ID+WFL++M+ I+ + L+ + + + L++AK +GFSDKQI+ + TE R+L
Sbjct: 421 YIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTREL 480
Query: 891 RQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVE 950
R + I P VKQIDT+AAE+P+ TNYLY+TY G HD+ F ++VLG G Y IGSSVE
Sbjct: 481 RLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVE 540
Query: 951 FDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEG 1010
FDWCAV I+ LR++G KT++VN NPETVSTD+D CD+LYF+E+S E ++DIY E G
Sbjct: 541 FDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGG 600
Query: 1011 VILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSD 1070
I+S+GGQ+PNN+A+ L++ +++GTSP ID AE+R FS +LD + ++Q W+ ++
Sbjct: 601 CIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNT 660
Query: 1071 LESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQ 1130
L A +F ++V YPC++RPSYVLSG+AMNV +++ ++++FL A VS+EHPVV++KF++
Sbjct: 661 LNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVE 720
Query: 1131 EAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVG 1190
A+E+++DAV DG V + AISEHVE+AGVHSGDATL+ P Q I+ +E++K +
Sbjct: 721 GAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIA 780
Query: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250
+ ++GPFN+Q + K + + VIECN+R SRSFPFVSKTLGVD + +AT+V++GE V+
Sbjct: 781 KAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEK 840
Query: 1251 GLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAML 1304
L T + V +K P FS+ RL AD +L EM STGEVA FGE A+LKAML
Sbjct: 841 HLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAML 900
Query: 1305 STGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDW 1364
STGFKIP+K IL+ I + L L + G+ L+A+ T+D+ + V T V W
Sbjct: 901 STGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAW 959
Query: 1365 HFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSV 1424
+E G+ P SI + + + + +LVINL + FV Y RR A D +
Sbjct: 960 PSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRTAVDSGI 1010
Query: 1425 PLIIDIKCTKLFVEAL 1440
PL+ + + TKLF EA+
Sbjct: 1011 PLLTNFQVTKLFAEAV 1026
Score = 154 bits (388), Expect = 1e-36
Identities = 110/393 (27%), Positives = 190/393 (48%), Gaps = 26/393 (6%)
Query: 396 VLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPI 455
+++LG G IG + EFD+ +I+ L++ +T+++N N TV T DK+YF +
Sbjct: 525 MMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEEL 584
Query: 456 TPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDR 515
+ + + E G +++ GGQ N V L K GV+++GT I+ EDR
Sbjct: 585 SLERILDIYHQEACGGCIISVGGQIPNNLAVPLYK------NGVKIMGTSPLQIDRAEDR 638
Query: 516 RAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELS 575
F+A + E+ AP +A N+L +A A+ + YP L+R ++ L G + +E+
Sbjct: 639 SIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMK 698
Query: 576 ALV--APAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIV 633
+ A + V++ K ++G +E+E + V G ++ E+++ G+H+G++ +
Sbjct: 699 KFLEEATRVSQEHPVVLTKFVEGAREVEMDAV-GKDGRVISHAISEHVEDAGVHSGDATL 757
Query: 634 VAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSAL 693
+ P+QT++ + ++ K+ + I G NVQ+ + + +IE N R SRS
Sbjct: 758 MLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLV--KGNDVLVIECNLRASRSFPF 815
Query: 694 ASKATGYPLAYVAAKLALG-----IPLPELRNSVTGGTAAFEPSVDYCVVKIPRWDLSKF 748
SK G VA K+ +G LP L + + DY +K P + +
Sbjct: 816 VSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPII--------PADYVAIKAPMFSWPR- 866
Query: 749 LRVSTKIGSC-MKSVGEVMGIGRSFEEAFQKAL 780
LR + I C M S GEV G AF KA+
Sbjct: 867 LRDADPILRCEMASTGEVACFGEGIHTAFLKAM 899
>gi|38788445 ornithine carbamoyltransferase precursor [Homo sapiens]
Length = 354
Score = 95.5 bits (236), Expect = 5e-19
Identities = 79/309 (25%), Positives = 141/309 (45%), Gaps = 10/309 (3%)
Query: 1921 LVGQHILSVQQFTKDQMSHLFNVAHTLRMMV-QKERSLDILKGKVMASMFYEVSTRTSSS 1979
L G+ +L+++ FT +++ ++ ++ L+ + QK L +L+GK + +F + STRT S
Sbjct: 37 LKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLS 96
Query: 1980 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 2039
A LGG + + ESL D+ + +S AD V+ R + ++ AK
Sbjct: 97 TETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEAS 156
Query: 2040 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRV 2099
P+IN + HP Q L D T++E ++ G+T++ +GD +HS+ ++ +
Sbjct: 157 IPIINGLSDL-YHPIQILADYLTLQEHYSSLKGLTLSWIGD--GNNILHSIMMSAAKFGM 213
Query: 2100 SLRYVAP----PSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYM-TRIQKERFGS 2154
L+ P P + + GTK EA +VL T I +
Sbjct: 214 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEE 273
Query: 2155 TQEYEACFGQFILTPHIMTRAKKKMVVMHPMPR-VNEISVEVDSDPRAAYFRQAENGMYI 2213
++ F + +T A +H +PR E+ EV PR+ F +AEN +
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWT 333
Query: 2214 RMALLATVL 2222
MA++ ++L
Sbjct: 334 IMAVMVSLL 342
>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 78.6 bits (192), Expect = 6e-14
Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%)
Query: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451
P +KV++ G ++I + +A E I+T+ I T Q + AD+ Y
Sbjct: 36 PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84
Query: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505
+ P+ + ++ +I+ + + V G L+ + +A A GVR +G
Sbjct: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142
Query: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563
E + D+ A G V P A SL +A + G+P++ +AA+ GG
Sbjct: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202
Query: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615
G + EEL A++ + V+K ++ + IE +++ D YGN + +
Sbjct: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262
Query: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673
C+++ + + +AP+ L+ + L ++K+ + +G V++ ++
Sbjct: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316
Query: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733
+ Y+ IEVN+RL + + T L + +A G LP+L G +
Sbjct: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369
Query: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
+ C + ++ D ++ + T +S GE MGI AFQ A+
Sbjct: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%)
Query: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079
+ A A R +G SPE + ++ + + G+ + ++ L A +F
Sbjct: 126 DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185
Query: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135
T G+P + + +Y G M V ++ +LE R S A A + + KFI++ + I
Sbjct: 186 TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245
Query: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190
+V + D + + E + + P PQ T T + +K + VG
Sbjct: 246 EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303
Query: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250
E T F L+ + + IE N R+ + VDLV V G + +
Sbjct: 304 YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301
GL + G + V + P SF G +E+ +GE G A+
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415
Query: 1302 AMLS 1305
A++S
Sbjct: 416 AVIS 419
>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 78.6 bits (192), Expect = 6e-14
Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%)
Query: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451
P +KV++ G ++I + +A E I+T+ I T Q + AD+ Y
Sbjct: 36 PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84
Query: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505
+ P+ + ++ +I+ + + V G L+ + +A A GVR +G
Sbjct: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142
Query: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563
E + D+ A G V P A SL +A + G+P++ +AA+ GG
Sbjct: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202
Query: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615
G + EEL A++ + V+K ++ + IE +++ D YGN + +
Sbjct: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262
Query: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673
C+++ + + +AP+ L+ + L ++K+ + +G V++ ++
Sbjct: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316
Query: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733
+ Y+ IEVN+RL + + T L + +A G LP+L G +
Sbjct: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369
Query: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
+ C + ++ D ++ + T +S GE MGI AFQ A+
Sbjct: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%)
Query: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079
+ A A R +G SPE + ++ + + G+ + ++ L A +F
Sbjct: 126 DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185
Query: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135
T G+P + + +Y G M V ++ +LE R S A A + + KFI++ + I
Sbjct: 186 TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245
Query: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190
+V + D + + E + + P PQ T T + +K + VG
Sbjct: 246 EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303
Query: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250
E T F L+ + + IE N R+ + VDLV V G + +
Sbjct: 304 YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301
GL + G + V + P SF G +E+ +GE G A+
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415
Query: 1302 AMLS 1305
A++S
Sbjct: 416 AVIS 419
>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 78.6 bits (192), Expect = 6e-14
Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%)
Query: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451
P +KV++ G ++I + +A E I+T+ I T Q + AD+ Y
Sbjct: 36 PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84
Query: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505
+ P+ + ++ +I+ + + V G L+ + +A A GVR +G
Sbjct: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142
Query: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563
E + D+ A G V P A SL +A + G+P++ +AA+ GG
Sbjct: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202
Query: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615
G + EEL A++ + V+K ++ + IE +++ D YGN + +
Sbjct: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262
Query: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673
C+++ + + +AP+ L+ + L ++K+ + +G V++ ++
Sbjct: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316
Query: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733
+ Y+ IEVN+RL + + T L + +A G LP+L G +
Sbjct: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369
Query: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
+ C + ++ D ++ + T +S GE MGI AFQ A+
Sbjct: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%)
Query: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079
+ A A R +G SPE + ++ + + G+ + ++ L A +F
Sbjct: 126 DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185
Query: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135
T G+P + + +Y G M V ++ +LE R S A A + + KFI++ + I
Sbjct: 186 TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245
Query: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190
+V + D + + E + + P PQ T T + +K + VG
Sbjct: 246 EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303
Query: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250
E T F L+ + + IE N R+ + VDLV V G + +
Sbjct: 304 YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301
GL + G + V + P SF G +E+ +GE G A+
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415
Query: 1302 AMLS 1305
A++S
Sbjct: 416 AVIS 419
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 518 FAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
F+ R+ + + + ++ AAE +GYPV+++A+ GG G +N ++ L
Sbjct: 274 FSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNL 333
Query: 578 VAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGES 631
A S + V + K + +E +++ D YGN +++ C+++ I +
Sbjct: 334 FRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA 393
Query: 632 IVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSS 691
+ P+ ++ + Q A+K+ + +G V V+Y L + +Y +E+N RL
Sbjct: 394 TIATPA------VFEHMEQCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEH 446
Query: 692 ALASKATGYPLAYVAAKLALGIPLPELRN 720
L ++A+GIPL +++
Sbjct: 447 PCTEMVADVNLPAAQLQIAMGIPLYRIKD 475
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 518 FAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
F+ R+ + + + ++ AAE +GYPV+++A+ GG G +N ++ L
Sbjct: 196 FSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNL 255
Query: 578 VAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGES 631
A S + V + K + +E +++ D YGN +++ C+++ I +
Sbjct: 256 FRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA 315
Query: 632 IVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSS 691
+ P+ ++ + Q A+K+ + +G V V+Y L + +Y +E+N RL
Sbjct: 316 TIATPA------VFEHMEQCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEH 368
Query: 692 ALASKATGYPLAYVAAKLALGIPLPELRN 720
L ++A+GIPL +++
Sbjct: 369 PCTEMVADVNLPAAQLQIAMGIPLYRIKD 397
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 518 FAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
F+ R+ + + + ++ AAE +GYPV+++A+ GG G +N ++ L
Sbjct: 216 FSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNL 275
Query: 578 VAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGES 631
A S + V + K + +E +++ D YGN +++ C+++ I +
Sbjct: 276 FRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA 335
Query: 632 IVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSS 691
+ P+ ++ + Q A+K+ + +G V V+Y L + +Y +E+N RL
Sbjct: 336 TIATPA------VFEHMEQCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEH 388
Query: 692 ALASKATGYPLAYVAAKLALGIPLPELRN 720
L ++A+GIPL +++
Sbjct: 389 PCTEMVADVNLPAAQLQIAMGIPLYRIKD 417
>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 518 FAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
F+ R+ + + + ++ AAE +GYPV+++A+ GG G +N ++ L
Sbjct: 274 FSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNL 333
Query: 578 VAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGES 631
A S + V + K + +E +++ D YGN +++ C+++ I +
Sbjct: 334 FRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA 393
Query: 632 IVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSS 691
+ P+ ++ + Q A+K+ + +G V V+Y L + +Y +E+N RL
Sbjct: 394 TIATPA------VFEHMEQCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEH 446
Query: 692 ALASKATGYPLAYVAAKLALGIPLPELRN 720
L ++A+GIPL +++
Sbjct: 447 PCTEMVADVNLPAAQLQIAMGIPLYRIKD 475
>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
sapiens]
Length = 2383
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 518 FAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSAL 577
F+ R+ + + + ++ AAE +GYPV+++A+ GG G +N ++ L
Sbjct: 311 FSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNL 370
Query: 578 VAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGES 631
A S + V + K + +E +++ D YGN +++ C+++ I +
Sbjct: 371 FRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA 430
Query: 632 IVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSS 691
+ P+ ++ + Q A+K+ + +G V V+Y L + +Y +E+N RL
Sbjct: 431 TIATPA------VFEHMEQCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEH 483
Query: 692 ALASKATGYPLAYVAAKLALGIPLPELRN 720
L ++A+GIPL +++
Sbjct: 484 PCTEMVADVNLPAAQLQIAMGIPLYRIKD 512
>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
Length = 2458
Score = 66.2 bits (160), Expect = 3e-10
Identities = 50/219 (22%), Positives = 102/219 (46%), Gaps = 14/219 (6%)
Query: 508 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF 567
T+E TED R++ + E V +++ AAER+G+P++++A+ GG G
Sbjct: 408 TVEWTEDDLQQGKRIS-VPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRK 466
Query: 568 ASNREELSALVAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENL 621
A + E+ L + S + + K + + +E +++ D YGN V++ C+++
Sbjct: 467 AESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR- 525
Query: 622 DPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYII 681
+ + AP+ ++ + Q AI++ + +G V V+Y L + ++ +
Sbjct: 526 -----RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFL 579
Query: 682 EVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN 720
E+N RL L ++A+G+PL L++
Sbjct: 580 ELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKD 618
>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform a precursor [Homo sapiens]
Length = 728
Score = 62.8 bits (151), Expect = 4e-09
Identities = 71/316 (22%), Positives = 133/316 (42%), Gaps = 28/316 (8%)
Query: 418 QAIKALKEENIQTLLINPNIATVQTSQGLADKVYFL---PITPHY-----VTQVIRNERP 469
+ I+ K+ I+T+ I+ ++ +AD+ + P + Y + + I+ R
Sbjct: 77 RVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRA 136
Query: 470 DGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDR--RAFAARMAEIGE 527
V +G L+ E + LA V +G I+ D+ A+ AE+
Sbjct: 137 QAVHPGYG---FLSENKEFARC--LAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNT 191
Query: 528 HVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREE------LSALVAPA 581
E+A A +GYPV+++A+ GG G A + EE LS+ A +
Sbjct: 192 IPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAAS 251
Query: 582 FAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVV--APSQT 639
++L++K + + IE +V+ D +GN + + E I VV APS
Sbjct: 252 SFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERE----CSIQRRNQKVVEEAPSIF 307
Query: 640 LNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATG 699
L+ + + + A+ + + + V++ ++ + +Y +E+N RL + TG
Sbjct: 308 LDAETRRAMGEQAVALARAVKYSSAGTVEFLVD-SKKNFYFLEMNTRLQVEHPVTECITG 366
Query: 700 YPLAYVAAKLALGIPL 715
L ++A G PL
Sbjct: 367 LDLVQEMIRVAKGYPL 382
Score = 46.6 bits (109), Expect = 3e-04
Identities = 65/305 (21%), Positives = 117/305 (38%), Gaps = 23/305 (7%)
Query: 959 IQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYF--------DEISFEVVMDIYELENPEG 1010
I+ +KMG KT+ ++ + + S M D ++ + +M+ + +
Sbjct: 79 IRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQA 138
Query: 1011 VILSMGGQLPN-NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE-- 1067
V G N A L + +G AI + ++ + L ++ +
Sbjct: 139 VHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGV 198
Query: 1068 LSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLE---RFLSSAAAVS-KEHPV 1123
+ D E A + + +GYP +++ S G M +A+ D + R S AA S + +
Sbjct: 199 VKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRL 258
Query: 1124 VISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTL---- 1179
+I KFI + I++ V D A+ ++E + + P + A+T
Sbjct: 259 LIEKFIDNPRHIEIQ-VLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMG 317
Query: 1180 ERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALAT 1239
E+ A+ AV T F L+ +E N R+ P G+DLV
Sbjct: 318 EQAVALARAVKYSSAGTVEF---LVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMI 374
Query: 1240 RVIMG 1244
RV G
Sbjct: 375 RVAKG 379
>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform b [Homo sapiens]
Length = 702
Score = 62.8 bits (151), Expect = 4e-09
Identities = 71/316 (22%), Positives = 133/316 (42%), Gaps = 28/316 (8%)
Query: 418 QAIKALKEENIQTLLINPNIATVQTSQGLADKVYFL---PITPHY-----VTQVIRNERP 469
+ I+ K+ I+T+ I+ ++ +AD+ + P + Y + + I+ R
Sbjct: 51 RVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRA 110
Query: 470 DGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDR--RAFAARMAEIGE 527
V +G L+ E + LA V +G I+ D+ A+ AE+
Sbjct: 111 QAVHPGYG---FLSENKEFARC--LAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNT 165
Query: 528 HVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREE------LSALVAPA 581
E+A A +GYPV+++A+ GG G A + EE LS+ A +
Sbjct: 166 IPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAAS 225
Query: 582 FAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVV--APSQT 639
++L++K + + IE +V+ D +GN + + E I VV APS
Sbjct: 226 SFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERE----CSIQRRNQKVVEEAPSIF 281
Query: 640 LNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATG 699
L+ + + + A+ + + + V++ ++ + +Y +E+N RL + TG
Sbjct: 282 LDAETRRAMGEQAVALARAVKYSSAGTVEFLVD-SKKNFYFLEMNTRLQVEHPVTECITG 340
Query: 700 YPLAYVAAKLALGIPL 715
L ++A G PL
Sbjct: 341 LDLVQEMIRVAKGYPL 356
Score = 46.6 bits (109), Expect = 3e-04
Identities = 65/305 (21%), Positives = 117/305 (38%), Gaps = 23/305 (7%)
Query: 959 IQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYF--------DEISFEVVMDIYELENPEG 1010
I+ +KMG KT+ ++ + + S M D ++ + +M+ + +
Sbjct: 53 IRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQA 112
Query: 1011 VILSMGGQLPN-NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE-- 1067
V G N A L + +G AI + ++ + L ++ +
Sbjct: 113 VHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGV 172
Query: 1068 LSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLE---RFLSSAAAVS-KEHPV 1123
+ D E A + + +GYP +++ S G M +A+ D + R S AA S + +
Sbjct: 173 VKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRL 232
Query: 1124 VISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTL---- 1179
+I KFI + I++ V D A+ ++E + + P + A+T
Sbjct: 233 LIEKFIDNPRHIEIQ-VLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMG 291
Query: 1180 ERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALAT 1239
E+ A+ AV T F L+ +E N R+ P G+DLV
Sbjct: 292 EQAVALARAVKYSSAGTVEF---LVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMI 348
Query: 1240 RVIMG 1244
RV G
Sbjct: 349 RVAKG 353
>gi|190194363 dihydropyrimidinase-like 4 [Homo sapiens]
Length = 572
Score = 57.0 bits (136), Expect = 2e-07
Identities = 118/528 (22%), Positives = 205/528 (38%), Gaps = 89/528 (16%)
Query: 1442 QIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITM 1499
QIG + + + + L+ LPG +DVH L+ P G T +DF GT AALAGG TM
Sbjct: 44 QIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTM 103
Query: 1500 VC--AMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGAS------SENAGTLGTVAGS 1551
+ P+T ++ A ++ A++ A CD++L + + E L G
Sbjct: 104 ILDHVFPDTGVSLL--AAYEQWRERADSAACCDYSLHVDITRWHESIKEELEALVKEKGV 161
Query: 1552 AAGLKL------------YLNETFSELR-LDSVVQ---------------WMEHFETWPS 1583
+ L + E FS +R L ++ Q +E T P
Sbjct: 162 NSFLVFMAYKDRCQCSDSQMYEIFSIIRDLGALAQVHAENGDIVEEEQKRLLELGITGPE 221
Query: 1584 HLPIVAHAEQQTVAAV---LMVAQLTQRSVHICHVARKEEILLIKAAKARGL-----PVT 1635
+++H E+ AV + +A+ +++ V K I AK RG+ P+T
Sbjct: 222 G-HVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADAIAQAKRRGVVVFGEPIT 280
Query: 1636 CEVAP--HHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLE 1693
+ H + + V P+ + + L + + S H T
Sbjct: 281 ASLGTDGSHYWSKNWAKAAAFVTSPPVNPDPTTADHLTCLLSS-GDLQVTGSAHCTFTTA 339
Query: 1694 EKCGSRP-----PPGFPGLETMLPLLL-TAVSEGRLSLDDLLQRLHHNPRRIFHLPPQED 1747
+K + P G G+E + ++ V+ G++ ++ + N +IF+ P++
Sbjct: 340 QKAVGKDNFALIPEGTNGIEERMSMVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKG 399
Query: 1748 TYV---EVDLEHEWTIPSHMPFSKAH-----WTPFEGQKVKGTVRRVVLRGEVAYIDGQV 1799
+ DL + + +K H + FEG + +G V+ +G VA DG++
Sbjct: 400 RVAVGSDADLVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQGRVALEDGKM 459
Query: 1800 LVPPGYGQDV--RKWPQ---------------GAVPQLPPSAPATSEMTTTPERPRRGIP 1842
V PG G+ V + +P VP+ P M P +P G P
Sbjct: 460 FVTPGAGRFVPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVM--VPAKPGSGAP 517
Query: 1843 GLPD--GRFHLPP-RIHRASDPGLPAEEPKEKSSRKVAEPELMGTPDG 1887
G+ +PP R S L + + +R+ A+ ++M P G
Sbjct: 518 ARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQ-KIMAPPGG 564
>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
precursor [Homo sapiens]
Length = 725
Score = 55.1 bits (131), Expect = 8e-07
Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 30/335 (8%)
Query: 418 QAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHY-----VTQVIRNERPDGV 472
+ ++ K+ +QT+ + +AD+ Y + P + ++I+ +
Sbjct: 63 RVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAA 122
Query: 473 LLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPS 532
G L+ +E A + + G+ +G P I + + MA G V
Sbjct: 123 QAIHPGCGFLSENMEF--AELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVV-- 178
Query: 533 EAANSLEQAQAA----AERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQ- 587
E + +Q+ A R+GYPV+++A GG G + +E + A +
Sbjct: 179 EGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKS 238
Query: 588 -----VLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGESIVVAPSQ 638
+L++K + + +E +V D +GN V + C+++ + I AP+
Sbjct: 239 FNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQR------RHQKIIEEAPAP 292
Query: 639 TLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKAT 698
+ + L + A++ + + VG V++ ++ + +E+N RL + T
Sbjct: 293 GIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMD-SKHNFCFMEMNTRLQVEHPVTEMIT 351
Query: 699 GYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733
G L ++A G +P + +T AFE +
Sbjct: 352 GTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARI 386
Score = 42.7 bits (99), Expect = 0.004
Identities = 53/301 (17%), Positives = 112/301 (37%), Gaps = 17/301 (5%)
Query: 963 RKMGYKTIMVNYNPETVSTDYDMCDRLYF--------DEISFEVVMDIYELENPEGVILS 1014
+K+G +T+ V + S DM D Y +S E ++ + + + +
Sbjct: 69 KKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPG 128
Query: 1015 MGGQLPNNMAMALHRQQCRV-LGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDL-- 1071
G N L +Q+ + +G P AI + ++ G+ + D
Sbjct: 129 CGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSD 188
Query: 1072 ESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSK----EHPVVISK 1127
+ ++ + +GYP +++ G M + ++ + + L SA +K + ++I K
Sbjct: 189 QCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEK 248
Query: 1128 FIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVH 1187
F+ + ++V V D A+ + E + P I ++ +++
Sbjct: 249 FVDTPRHVEVQ-VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAV 307
Query: 1188 AVGQELQVTGPFNLQLIAKDDQ-LKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEE 1246
+ + G ++ I +E N R+ P G DLV R+ GE+
Sbjct: 308 RAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEK 367
Query: 1247 V 1247
+
Sbjct: 368 I 368
>gi|19923821 dihydropyrimidinase-like 5 [Homo sapiens]
Length = 564
Score = 52.0 bits (123), Expect = 7e-06
Identities = 93/424 (21%), Positives = 162/424 (38%), Gaps = 67/424 (15%)
Query: 1460 KLVRLPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVC--AMPNTRPPIIDAPA 1515
KLV +PG ID H + T +DF GT AAL GG TM+ +P+ ++D A
Sbjct: 56 KLV-IPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVD--A 112
Query: 1516 LALAQKLAEAGARCDFALFLGA---SSENAGTLGTVAGSAAGLKLYLNETFSELRL--DS 1570
+ LA+ CD+AL +G + + + T+ + T+ +L + DS
Sbjct: 113 YEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDS 172
Query: 1571 VVQWMEHF-----------------------------ETWPSHLPIVAHAEQQTVAA--V 1599
+ + H T P + I E + A V
Sbjct: 173 ELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRV 232
Query: 1600 LMVAQLTQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLS-----HDDLERLG 1654
+ +A T +++ +V+ +I AAK +G V E H L+ H D
Sbjct: 233 ITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAA 292
Query: 1655 P--GKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRP-----PPGFPGL 1707
+R + + + +L N ++ ASDH P T ++K + P G G+
Sbjct: 293 AYVTVPPLRLDTNTSTYLMSLLAN-DTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGV 351
Query: 1708 ETMLPLLL-TAVSEGRLSLDDLLQRLHHNPRRIFHLPPQE-------DTYVEV-DLEHEW 1758
+ + ++ V G++ + + N ++ +L P++ D V V D E
Sbjct: 352 QDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATK 411
Query: 1759 TIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQ--DVRKWPQGA 1816
TI + + +E + G + RG V Y +G + G G+ +R +P
Sbjct: 412 TISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTV 471
Query: 1817 VPQL 1820
+L
Sbjct: 472 YKKL 475
>gi|4503379 dihydropyrimidinase-like 3 [Homo sapiens]
Length = 570
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 1464 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 1521
+PG IDVH H + P G T +DF GT AALAGG TM+ P A ++
Sbjct: 66 IPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWRE 125
Query: 1522 LAEAGARCDFALFLGASSEN 1541
A+ + CD+AL + + N
Sbjct: 126 WADGKSCCDYALHVDITHWN 145
Score = 35.4 bits (80), Expect = 0.63
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 39/213 (18%)
Query: 1701 PPGFPGLETMLPLLLT-AVSEGRLSLDDLLQRLHHNPRRIFHLPPQ--------EDTYVE 1751
P G G+E + ++ AV+ G++ + + N +IF+L P+ + V
Sbjct: 352 PEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVI 411
Query: 1752 VDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRK 1811
D + + + S A + FEG +++G V+ +G++ DG + V G G+ +
Sbjct: 412 WDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPC 471
Query: 1812 WPQG-----------------AVPQLPPSAPATSEMTT----TPERPRRGIPGLPDGRFH 1850
P AVP+ P TT TP RG P P+
Sbjct: 472 SPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPN---- 527
Query: 1851 LPP--RIHRA--SDPGLPAEEPKEKSSRKVAEP 1879
PP +H++ S G +E +S+++ P
Sbjct: 528 -PPVRNLHQSGFSLSGTQVDEGVRSASKRIVAP 559
>gi|4503377 dihydropyrimidinase-like 2 [Homo sapiens]
Length = 572
Score = 45.8 bits (107), Expect = 5e-04
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 1464 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 1521
+PG IDVH + P G T +DF GT AALAGG TM+ P A ++
Sbjct: 66 IPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWRE 125
Query: 1522 LAEAGARCDFALFLGASSENAG 1543
A++ + CD++L + S + G
Sbjct: 126 WADSKSCCDYSLHVDISEWHKG 147
Score = 32.7 bits (73), Expect = 4.1
Identities = 28/122 (22%), Positives = 55/122 (45%), Gaps = 9/122 (7%)
Query: 1701 PPGFPGLETMLPLLLT-AVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYV---EVDL-- 1754
P G G E + ++ AV G++ + + N ++F+L P++ + DL
Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVI 411
Query: 1755 ---EHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRK 1811
+ TI + S + FEG + +G+ V+ +G++ DG + V G G+ + +
Sbjct: 412 WDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471
Query: 1812 WP 1813
P
Sbjct: 472 KP 473
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens]
Length = 505
Score = 44.7 bits (104), Expect = 0.001
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 11/96 (11%)
Query: 1814 QGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDPGLPAEEPKEKSS 1873
+GA P P AP + P RP +P P R + PP P LP+ P S
Sbjct: 307 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPP------PPALPSSAP---SG 357
Query: 1874 RKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGL 1909
P ++G G PPPP P P PGL
Sbjct: 358 PPPPPPSVLGV--GPVAPPPPPPPPPPPGPPPPPGL 391
>gi|4503375 dihydropyrimidinase [Homo sapiens]
Length = 519
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 7/83 (8%)
Query: 1460 KLVRLPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVC--AMPNTRPPIIDAPA 1515
KLV LPG ID H H++ P G +DF GT AAL+GG TM+ A+P +I+ A
Sbjct: 57 KLV-LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIE--A 113
Query: 1516 LALAQKLAEAGARCDFALFLGAS 1538
+ A+ CD++L + +
Sbjct: 114 FETWRSWADPKVCCDYSLHVAVT 136
>gi|62422571 collapsin response mediator protein 1 isoform 1 [Homo
sapiens]
Length = 686
Score = 42.4 bits (98), Expect = 0.005
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 1464 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 1521
+PG IDV+ +L++P G T +DF GT AAL GG TM+ P + +
Sbjct: 180 IPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHE 239
Query: 1522 LAEAGARCDFALFLGASS 1539
A+ + CD++L + +S
Sbjct: 240 AADTKSCCDYSLHVDITS 257
Score = 40.4 bits (93), Expect = 0.020
Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
Query: 1685 SDHAPHTLEEKCGSRP-----PPGFPGLETMLPLLLT-AVSEGRLSLDDLLQRLHHNPRR 1738
S H P++ +K + P G G+E + ++ AV+ G++ + + N +
Sbjct: 445 SGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAK 504
Query: 1739 IFHLPPQE-------DTYVEV-DLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRG 1790
IF+L P++ D V + D + TI + S + FEG + G+ V+ +G
Sbjct: 505 IFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQG 564
Query: 1791 EVAYIDGQVLVPPGYGQDVRKWPQGAVPQ 1819
++ + DG + V G G+ + P+ A P+
Sbjct: 565 KIVFEDGNINVNKGMGRFI---PRKAFPE 590
>gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo
sapiens]
Length = 572
Score = 42.4 bits (98), Expect = 0.005
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 1464 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 1521
+PG IDV+ +L++P G T +DF GT AAL GG TM+ P + +
Sbjct: 66 IPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHE 125
Query: 1522 LAEAGARCDFALFLGASS 1539
A+ + CD++L + +S
Sbjct: 126 AADTKSCCDYSLHVDITS 143
Score = 40.4 bits (93), Expect = 0.020
Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
Query: 1685 SDHAPHTLEEKCGSRP-----PPGFPGLETMLPLLLT-AVSEGRLSLDDLLQRLHHNPRR 1738
S H P++ +K + P G G+E + ++ AV+ G++ + + N +
Sbjct: 331 SGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAK 390
Query: 1739 IFHLPPQE-------DTYVEV-DLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRG 1790
IF+L P++ D V + D + TI + S + FEG + G+ V+ +G
Sbjct: 391 IFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQG 450
Query: 1791 EVAYIDGQVLVPPGYGQDVRKWPQGAVPQ 1819
++ + DG + V G G+ + P+ A P+
Sbjct: 451 KIVFEDGNINVNKGMGRFI---PRKAFPE 476
>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
Length = 1133
Score = 41.6 bits (96), Expect = 0.009
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 40/219 (18%)
Query: 1685 SDHAPHTLEEKC-GSRPPPGFPGLETMLPLLLTAVSEGRL-SLDDLLQRLHHNPRRIFHL 1742
S H P E+ G PP L+T LT + S DD ++ R L
Sbjct: 859 SRHLPSVCGERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRG--PL 916
Query: 1743 PPQEDTYVEVDLEHEWT-IPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLV 1801
PP D ++ E + T +P P P +K R LRG +
Sbjct: 917 PPSADDNLKTPSERQLTPLPPSAP-------PSADDNIKTPAER--LRGPL--------- 958
Query: 1802 PPGYGQDVRKWPQGAVPQLPPSAPATSE--MTTTPERPRRGIPGLPDGRFHLPPRIHRAS 1859
PP +++ + + LPPSAP +++ + T ER R +P D PP + +
Sbjct: 959 PPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPPLATQEA 1018
Query: 1860 DPGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQ 1898
+ AE+P++ ++ AE E PPP P++
Sbjct: 1019 E----AEKPRKPKRQRAAEME-----------PPPEPKR 1042
Score = 35.8 bits (81), Expect = 0.48
Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 43/217 (19%)
Query: 1700 PPPGFPGLETMLPLLLTAVSEGRL-----SLDDLLQRLHHNPRRIFH-LPPQEDTYVEVD 1753
PP L+T LLT + L S DD L+ + H LPP D ++
Sbjct: 332 PPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKT---RAECLLHPLPPSADDNLKTP 388
Query: 1754 LEHEWT-IPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKW 1812
E + T +P P P +K R LRG + PP +++
Sbjct: 389 SERQLTPLPPSAP-------PSADDNIKTPAER--LRGPL---------PPSADDNLKTP 430
Query: 1813 PQGAVPQLPPSAP--ATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDPGLPAEEPKE 1870
+ + LPPSAP A + T ER R +P D P R P P+ P
Sbjct: 431 SERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPS--ERQLTPLPPSAPPSA 488
Query: 1871 KSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTP 1907
+ K L G P PP ++ NL TP
Sbjct: 489 DDNIKTPAERLRG-------PLPP----SADDNLKTP 514
Score = 34.3 bits (77), Expect = 1.4
Identities = 45/171 (26%), Positives = 62/171 (36%), Gaps = 34/171 (19%)
Query: 1742 LPPQEDTYVEVDLEHEWT-IPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL 1800
LPP D ++ E + T +P P P +K R LRG +
Sbjct: 874 LPPSADDNLKTPSERQLTPLPPSAP-------PSADDNIKTPAER--LRGPL-------- 916
Query: 1801 VPPGYGQDVRKWPQGAVPQLPPSAP--ATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRA 1858
PP +++ + + LPPSAP A + T ER R +P D P R
Sbjct: 917 -PPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPS--ERQ 973
Query: 1859 SDPGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGL 1909
P P+ P + K L G P PP ++ NL TP L
Sbjct: 974 LTPLPPSAPPSADDNIKTPAERLRG-------PLPP----SADDNLKTPPL 1013
Score = 31.6 bits (70), Expect = 9.1
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 17/119 (14%)
Query: 1801 VPPGYGQDVRKWPQGAVPQLPPSAP--ATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRA 1858
+PP +++ + + LPPSAP A + T ER R +P D P R
Sbjct: 377 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPS--ERQ 434
Query: 1859 SDPGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPL 1917
P P+ P + K L G P PP ++ NL TP Q +PL
Sbjct: 435 LTPLPPSAPPSADDNIKTPAERLRG-------PLPP----SADDNLKTPS--ERQLTPL 480
Score = 31.6 bits (70), Expect = 9.1
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 17/119 (14%)
Query: 1801 VPPGYGQDVRKWPQGAVPQLPPSAP--ATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRA 1858
+PP +++ + + LPPSAP A + T ER R +P D P R
Sbjct: 874 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPS--ERQ 931
Query: 1859 SDPGLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPL 1917
P P+ P + K L G P PP ++ NL TP Q +PL
Sbjct: 932 LTPLPPSAPPSADDNIKTPAERLRG-------PLPP----SADDNLKTPS--ERQLTPL 977
>gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 41.6 bits (96), Expect = 0.009
Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1816 AVPQLPPSAPATSEMTTTPERPRRG-----IPGLPDGRFHLPPRIHRASDPGLPAEEPKE 1870
A P L PS A +E + P P RG P PDG S P P P
Sbjct: 275 AAPALQPSQAAPAEGVSQPA-PARGDFAYAAPAPPDGAL---------SHPQAPRWPPHP 324
Query: 1871 KSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTS 1915
SR+ +P+ G P G C P P QA PQ G+L P TS
Sbjct: 325 GKSREDRDPQRDGLP-GPCAVAQPGPAQAGPQG---QGVLAPPTS 365
>gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]
Length = 483
Score = 41.6 bits (96), Expect = 0.009
Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1816 AVPQLPPSAPATSEMTTTPERPRRG-----IPGLPDGRFHLPPRIHRASDPGLPAEEPKE 1870
A P L PS A +E + P P RG P PDG S P P P
Sbjct: 275 AAPALQPSQAAPAEGVSQPA-PARGDFAYAAPAPPDGAL---------SHPQAPRWPPHP 324
Query: 1871 KSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTS 1915
SR+ +P+ G P G C P P QA PQ G+L P TS
Sbjct: 325 GKSREDRDPQRDGLP-GPCAVAQPGPAQAGPQG---QGVLAPPTS 365
>gi|194272172 double homeobox, 4 [Homo sapiens]
Length = 485
Score = 41.6 bits (96), Expect = 0.009
Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1816 AVPQLPPSAPATSEMTTTPERPRRG-----IPGLPDGRFHLPPRIHRASDPGLPAEEPKE 1870
A P L PS A +E + P P RG P PDG S P P P
Sbjct: 275 AAPALQPSQAAPAEGVSQPA-PARGDFAYAAPAPPDGAL---------SHPQAPRWPPHP 324
Query: 1871 KSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTS 1915
SR+ +P+ G P G C P P QA PQ G+L P TS
Sbjct: 325 GKSREDRDPQRDGLP-GPCAVAQPGPAQAGPQG---QGVLAPPTS 365
>gi|194272217 double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 41.6 bits (96), Expect = 0.009
Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1816 AVPQLPPSAPATSEMTTTPERPRRG-----IPGLPDGRFHLPPRIHRASDPGLPAEEPKE 1870
A P L PS A +E + P P RG P PDG S P P P
Sbjct: 275 AAPALQPSQAAPAEGVSQPA-PARGDFAYAAPAPPDGAL---------SHPQAPRWPPHP 324
Query: 1871 KSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTS 1915
SR+ +P+ G P G C P P QA PQ G+L P TS
Sbjct: 325 GKSREDRDPQRDGLP-GPCAVAQPGPAQAGPQG---QGVLAPPTS 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,220,670
Number of Sequences: 37866
Number of extensions: 4333986
Number of successful extensions: 14184
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 13173
Number of HSP's gapped (non-prelim): 1069
length of query: 2225
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2107
effective length of database: 13,779,330
effective search space: 29033048310
effective search space used: 29033048310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.