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Search of human proteins with 17999520
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 1063 0.0
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 90 6e-18
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 78 2e-14
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 69 8e-12
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 67 4e-11
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 67 4e-11
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 64 3e-10
gi|117168277 amino acid transporter system A1 [Homo sapiens] 64 3e-10
gi|117168275 amino acid transporter system A1 [Homo sapiens] 64 3e-10
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 63 6e-10
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 63 6e-10
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 61 2e-09
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 55 1e-07
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 49 1e-05
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 48 3e-05
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 46 7e-05
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 45 1e-04
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 45 1e-04
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 38 0.020
gi|112382239 desmuslin isoform B [Homo sapiens] 31 2.4
gi|112382237 desmuslin isoform A [Homo sapiens] 31 2.4
gi|44662807 hypothetical protein LOC388407 [Homo sapiens] 31 2.4
gi|84662753 G protein-coupled receptor 149 [Homo sapiens] 31 3.2
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 30 5.4
gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo... 30 7.1
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 29 9.2
gi|157388943 transmembrane protein 104 [Homo sapiens] 29 9.2
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 1063 bits (2750), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM 60
MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM
Sbjct: 1 MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM 60
Query: 61 DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE 120
DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE
Sbjct: 61 DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE 120
Query: 121 AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV 180
AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV
Sbjct: 121 AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV 180
Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ
Sbjct: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
Query: 241 KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY 300
KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY
Sbjct: 241 KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY 300
Query: 301 IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL 360
IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL
Sbjct: 301 IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL 360
Query: 361 TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA 420
TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA
Sbjct: 361 TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA 420
Query: 421 CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL
Sbjct: 421 CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
Query: 481 LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED 525
LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED
Sbjct: 481 LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED 525
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 89.7 bits (221), Expect = 6e-18
Identities = 94/439 (21%), Positives = 184/439 (41%), Gaps = 40/439 (9%)
Query: 107 EFGGHDKPK-ITAWEAGWNVTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCCYTGK 164
E G K K IT ++A ++ G +LGLP A+ + G L G ++ + C+
Sbjct: 44 ESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMH 103
Query: 165 ILIACLYE--ENEDGEVVRVRDSYVAIANA---CCAPRFPTLGGRVVNVAQIIELVMTCI 219
IL+ C + + + D+ + A G +V+ II + C
Sbjct: 104 ILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCC 163
Query: 220 LYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPC-----------------AFLKNLKA 262
+Y+V + + + + + T +L P ++NL+
Sbjct: 164 VYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRI 223
Query: 263 VSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIF 322
++ FS+L ++ V +++I Y D + ++ K +P+ G +FS+ S
Sbjct: 224 LTIFSMLANISMLVSLVIIIQYITQEIPDPS--RLPLVASWKTYPLFFGTAIFSFESIGV 281
Query: 323 LPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS-IRAV 381
+ LE M+ F +++ L A + YL + D+ K I+ NLP +
Sbjct: 282 VLPLENKMKNARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLPNCWLYQS 341
Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEK-SLFQEGSRAFFPACYSGDGRLKSWGLTLRCALV 440
V + +A L +Y L F+ E++ ++ + +R P L++R +V
Sbjct: 342 VKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPL-----------DLSIRLVMV 390
Query: 441 VFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRK-LLWHQVFFDVAIFVI 499
T L+AI +P L++ L GS++G L ++P L + + + + +F D I ++
Sbjct: 391 CLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISIL 450
Query: 500 GGICSVSGFVHSLEGLIEA 518
G + V G +L+ L+++
Sbjct: 451 GFVGFVVGTYQALDELLKS 469
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 77.8 bits (190), Expect = 2e-14
Identities = 97/451 (21%), Positives = 186/451 (41%), Gaps = 42/451 (9%)
Query: 95 PSGSKDQVGGGGEFGGHDKPKITAW-EAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLI 152
PS + + G + + T W + ++ G +LGLP A+ + G +G +
Sbjct: 25 PSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISL 84
Query: 153 IFAAVVCCYTGKILIACLYE--ENEDGEVVRVRDSYV-AIANACCA--PRFPTLGGRVVN 207
+ +V + IL+ C + + V D+ + + ++ C+ G RVV+
Sbjct: 85 LIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVD 144
Query: 208 VAQII-ELVMTCILYVVVSGNLM-------------YNS-----FPGLPVSQKSWSIIAT 248
I+ +L C+ +V ++ N +N+ P + S +
Sbjct: 145 FFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPF 204
Query: 249 AVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPI 308
VLL F++NL+A+S FSLL + V +++ + + R D + + K +P+
Sbjct: 205 LVLL--VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPS--HLPLVAPWKTYPL 260
Query: 309 SIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKE 368
G +FS+ + LE M+ P +F ++ + +L + YL + +
Sbjct: 261 FFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQG 320
Query: 369 VITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGR 427
IT NLP + V + +Y L F+ E++ FF +
Sbjct: 321 SITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP---------FFVSRAPEHCE 371
Query: 428 LKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRK-LL 486
L L +R LV T ++AI +P L++ L GS++ + L ++P L + + + +
Sbjct: 372 LVV-DLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMS 430
Query: 487 WHQVFFDVAIFVIGGICSVSGFVHSLEGLIE 517
+F D I ++G + V G +L LI+
Sbjct: 431 PLTIFKDALISILGFVGFVVGTYEALYELIQ 461
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 69.3 bits (168), Expect = 8e-12
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 74/402 (18%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACL-------YEEN 174
+N++NAI G +LGL YA+ H G + L L++ A++ Y+ +L+ C YE+
Sbjct: 55 FNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQL 114
Query: 175 EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYV------VVSGNL 228
G+ V +A C + + + + LV+ LY+ + GNL
Sbjct: 115 --GQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNL 172
Query: 229 MYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYC 285
+ I++ ++LP A +K+L + S SL C L F+++++ +
Sbjct: 173 LI-------------IIVSVLIILPLALMKHLGYLGYTSGLSLTCML-FFLVSVIYKKFQ 218
Query: 286 L--------------------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPS 325
L S+ + + E F +D + ++ I+ F++ +
Sbjct: 219 LGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVD-SQMSYTVPIMAFAFVCHPEVLP 277
Query: 326 LEGNMQQPSE--FHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITD--NLPGSIRAV 381
+ + +PS+ + N + A + GL A YLT+ K + + +
Sbjct: 278 IYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILC 337
Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVV 441
V + ++ L+ P+ F L++ LF G+ SW + AL++
Sbjct: 338 VRLAVLLAVTLTVPVVLFPIRRALQQLLFP--------------GKAFSWPRHVAIALIL 383
Query: 442 FTLL--MAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
L+ + I VP + G+ GS + L F+LPS+F+LR++
Sbjct: 384 LVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIV 425
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/276 (21%), Positives = 117/276 (42%), Gaps = 22/276 (7%)
Query: 243 WSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYID 302
+ +I L+ F++NLK +S FS L + L+ Y + + + +
Sbjct: 233 YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPS--NLPLMAN 290
Query: 303 VKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW 362
K F + G +F++ + L+ M+ P +F ++ +L L + Y+ +
Sbjct: 291 WKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKF 350
Query: 363 ADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPAC 421
+T+ IT NLP + V + +Y L F E++ + S
Sbjct: 351 GSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVS------- 403
Query: 422 YSGDGRLKSWGL----TLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
+SW L ++R ALV T + AI +P L++ L GS++ + L ++P+L
Sbjct: 404 -------ESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 456
Query: 478 LRLLWRK-LLWHQVFFDVAIFVIGGICSVSGFVHSL 512
+ + + + + + D+ I ++G + + G +L
Sbjct: 457 IVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQAL 492
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/276 (21%), Positives = 117/276 (42%), Gaps = 22/276 (7%)
Query: 243 WSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYID 302
+ +I L+ F++NLK +S FS L + L+ Y + + + +
Sbjct: 192 YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPS--NLPLMAN 249
Query: 303 VKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW 362
K F + G +F++ + L+ M+ P +F ++ +L L + Y+ +
Sbjct: 250 WKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKF 309
Query: 363 ADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPAC 421
+T+ IT NLP + V + +Y L F E++ + S
Sbjct: 310 GSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVS------- 362
Query: 422 YSGDGRLKSWGL----TLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
+SW L ++R ALV T + AI +P L++ L GS++ + L ++P+L
Sbjct: 363 -------ESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 415
Query: 478 LRLLWRK-LLWHQVFFDVAIFVIGGICSVSGFVHSL 512
+ + + + + + D+ I ++G + + G +L
Sbjct: 416 IVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQAL 451
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 64.3 bits (155), Expect = 3e-10
Identities = 79/377 (20%), Positives = 147/377 (38%), Gaps = 42/377 (11%)
Query: 131 GMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACL------YEENEDGEVVRVR 183
G +LGLP AI + G LG ++F ++ + IL+ C ++++ G V
Sbjct: 74 GTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVS 133
Query: 184 DSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL------- 236
+ + ++ C + G VV+ +I + C +Y+V + G
Sbjct: 134 FA-MEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFI 192
Query: 237 --------PVSQKSWSI-IATAVLLP----CAFLKNLKAVSKFSLLCTLAHFVINILVIA 283
P ++S + I LP F++ LK + S L ++ V +++
Sbjct: 193 SNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQ 252
Query: 284 YCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWT 343
Y + D + KK+P+ G VF++ + LE M++ F +N
Sbjct: 253 YVVRNMPDP--HNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIG 310
Query: 344 HIAACVLKGLFALVAYLTWADETKEVITDNLPGSI--RAVVNIFLVAKALLSYPLPFFAA 401
L A + Y+ + DE K IT NLP + V I ++Y + F+
Sbjct: 311 MGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVP 370
Query: 402 VEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTG 461
E++ + + + C G +R LV T AI +P +++ G
Sbjct: 371 AEIIIPGITSKFHTKWKQICEFG----------IRSFLVSITCAGAILIPRLDIVISFVG 420
Query: 462 SLTGAGLCFLLPSLFHL 478
+++ + L +LP L +
Sbjct: 421 AVSSSTLALILPPLVEI 437
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 63.9 bits (154), Expect = 3e-10
Identities = 86/394 (21%), Positives = 164/394 (41%), Gaps = 66/394 (16%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAV--VCCYTGKILIACLYEENEDGEVV 180
+N++NAI G +LGL +A+ + G L LFL++ +V + Y+ +L+ C E G +V
Sbjct: 78 FNLSNAIMGSGILGLAFALANTGIL-LFLVLLTSVTLLSIYSINLLLIC---SKETGCMV 133
Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
Y + F T G V+ A ++ + Y+ + N + ++ L +
Sbjct: 134 -----YEKLGEQV----FGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKE 184
Query: 241 KSWS-----------IIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAY-- 284
+++S I+ ++LP LKNL + S FSL C V ++V+ Y
Sbjct: 185 ETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSC----MVFFLIVVIYKK 240
Query: 285 ----CL---------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQ 331
C+ + + + K+ K ++ I F++ + + ++
Sbjct: 241 FQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300
Query: 332 QPSEFHCMM--NWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS---IRAVVNIFL 386
S+ M N + A V+ L A+ YLT+ D + + + V + +
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360
Query: 387 VAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLM 446
+ +L+ P+ FF + SLF+ + F C + C L+V L+
Sbjct: 361 IVAVILTVPVLFFT----VRSSLFELAKKTKFNLCRH---------TVVTCILLVVINLL 407
Query: 447 AIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
I++P + G+ G + L F+LPS +L++
Sbjct: 408 VIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKI 441
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 63.9 bits (154), Expect = 3e-10
Identities = 86/394 (21%), Positives = 164/394 (41%), Gaps = 66/394 (16%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAV--VCCYTGKILIACLYEENEDGEVV 180
+N++NAI G +LGL +A+ + G L LFL++ +V + Y+ +L+ C E G +V
Sbjct: 78 FNLSNAIMGSGILGLAFALANTGIL-LFLVLLTSVTLLSIYSINLLLIC---SKETGCMV 133
Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
Y + F T G V+ A ++ + Y+ + N + ++ L +
Sbjct: 134 -----YEKLGEQV----FGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKE 184
Query: 241 KSWS-----------IIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAY-- 284
+++S I+ ++LP LKNL + S FSL C V ++V+ Y
Sbjct: 185 ETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSC----MVFFLIVVIYKK 240
Query: 285 ----CL---------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQ 331
C+ + + + K+ K ++ I F++ + + ++
Sbjct: 241 FQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300
Query: 332 QPSEFHCMM--NWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS---IRAVVNIFL 386
S+ M N + A V+ L A+ YLT+ D + + + V + +
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360
Query: 387 VAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLM 446
+ +L+ P+ FF + SLF+ + F C + C L+V L+
Sbjct: 361 IVAVILTVPVLFFT----VRSSLFELAKKTKFNLCRH---------TVVTCILLVVINLL 407
Query: 447 AIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
I++P + G+ G + L F+LPS +L++
Sbjct: 408 VIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKI 441
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 63.2 bits (152), Expect = 6e-10
Identities = 89/442 (20%), Positives = 185/442 (41%), Gaps = 53/442 (11%)
Query: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
W N+ N+I G+ VL +P+ G LG L++F + + + L+
Sbjct: 9 WGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK--------S 60
Query: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP 237
+ R +Y +A + G +V + I ++ TCI + VV G+L N F L
Sbjct: 61 ASLSKRRTYAGLAFHA----YGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLF 116
Query: 238 VSQKSWSI-------IATAVLLPCAFLKNLKA-VSKFSLLCTLAHFVINILVIAYCLSRA 289
Q + ++ ++LP + +N+ A + FS + L + V +++ L
Sbjct: 117 GFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHG 176
Query: 290 R-DWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAAC 348
W + Y+ + I I S+ Q + ++ +PS M + +
Sbjct: 177 LFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPS-VKTMSSIFASSLN 235
Query: 349 VLKGLFALVA---YLTWADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEV 404
V+ + +V Y+++ + T + + P + + ++ + + + +P+ +
Sbjct: 236 VVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQA 295
Query: 405 LEKSLFQEGSR--AFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGS 462
L L ++ + F Y R K+ L ++V T++ I +P+ ++GLTG+
Sbjct: 296 LSTLLCEQQQKDGTFAAGGYMPPLRFKA----LTLSVVFGTMVGGILIPNVETILGLTGA 351
Query: 463 LTGAGLCFLLPSLFHLRLLWRKLLWHQV--FFDVAIFVIGGICSVS-------------- 506
G+ +CF+ P+L + + + + L QV + + + V+ + ++S
Sbjct: 352 TMGSLICFICPALIY-KKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAP 410
Query: 507 -GFVHSLEGL--IEAYRTNAED 525
G + EGL +EA R +A+D
Sbjct: 411 GGRLGEAEGLMKVEAARLSAQD 432
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 63.2 bits (152), Expect = 6e-10
Identities = 89/442 (20%), Positives = 185/442 (41%), Gaps = 53/442 (11%)
Query: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
W N+ N+I G+ VL +P+ G LG L++F + + + L+
Sbjct: 9 WGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK--------S 60
Query: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP 237
+ R +Y +A + G +V + I ++ TCI + VV G+L N F L
Sbjct: 61 ASLSKRRTYAGLAFHA----YGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLF 116
Query: 238 VSQKSWSI-------IATAVLLPCAFLKNLKA-VSKFSLLCTLAHFVINILVIAYCLSRA 289
Q + ++ ++LP + +N+ A + FS + L + V +++ L
Sbjct: 117 GFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHG 176
Query: 290 R-DWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAAC 348
W + Y+ + I I S+ Q + ++ +PS M + +
Sbjct: 177 LFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPS-VKTMSSIFASSLN 235
Query: 349 VLKGLFALVA---YLTWADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEV 404
V+ + +V Y+++ + T + + P + + ++ + + + +P+ +
Sbjct: 236 VVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQA 295
Query: 405 LEKSLFQEGSR--AFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGS 462
L L ++ + F Y R K+ L ++V T++ I +P+ ++GLTG+
Sbjct: 296 LSTLLCEQQQKDGTFAAGGYMPPLRFKA----LTLSVVFGTMVGGILIPNVETILGLTGA 351
Query: 463 LTGAGLCFLLPSLFHLRLLWRKLLWHQV--FFDVAIFVIGGICSVS-------------- 506
G+ +CF+ P+L + + + + L QV + + + V+ + ++S
Sbjct: 352 TMGSLICFICPALIY-KKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAP 410
Query: 507 -GFVHSLEGL--IEAYRTNAED 525
G + EGL +EA R +A+D
Sbjct: 411 GGRLGEAEGLMKVEAARLSAQD 432
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 61.2 bits (147), Expect = 2e-09
Identities = 90/403 (22%), Positives = 166/403 (41%), Gaps = 65/403 (16%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGL-FLIIFAAVVCCYTGKILIACLYE----ENED- 176
+N+ NAI G +LGL Y + + G G FL++ A++ Y+ +L++ + ED
Sbjct: 52 FNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDL 111
Query: 177 GEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL 236
G + +A G + + II+ + + ++G+ Y+ + L
Sbjct: 112 GLFAFGLPGKLVVAGTIIIQNI----GAMSSYLLIIKTELPAAIAEFLTGD--YSRYWYL 165
Query: 237 PVSQKSWSIIATAVLLPCAFLKNLK--------------------AVSKFSLLCTLAHFV 276
Q II ++ P A L + + K+S+ C L
Sbjct: 166 D-GQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLT--- 221
Query: 277 INILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEF 336
+N + + +S D K K + K+ ++ + FS+ + + +Q PS+
Sbjct: 222 LNYVEKGFQISNVTDDC--KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKK 279
Query: 337 HCMMNWTHIAACV---LKGLFALVAYLTWADETKEVITDNLPGSIR-----AVVNIFLVA 388
M N T+ A + + + AL YLT+ D+ + + + V + ++
Sbjct: 280 R-MQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILF 338
Query: 389 KALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAI 448
LL+ PL F A + + F FP + ++ + +TL AL + +L+AI
Sbjct: 339 AVLLTVPLIHFPARKAVTMMFFSN-----FPFSW-----IRHFLITL--ALNIIIVLLAI 386
Query: 449 YVPHFALLMGLTGSLTGAGLCFLLPSLFHLR------LLWRKL 485
YVP + G+ G+ T L F+ P LF+L+ L W+KL
Sbjct: 387 YVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKL 429
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 55.5 bits (132), Expect = 1e-07
Identities = 87/429 (20%), Positives = 174/429 (40%), Gaps = 62/429 (14%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181
+N++NAI G +LGL YA+ + G L + L+ F ++ Y+ +L L NE G ++
Sbjct: 78 FNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLL---LKTANEGGSLLY 134
Query: 182 VRDSY--------VAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSF 233
+ Y +A + + + + V + LV+ + + L Y +
Sbjct: 135 EQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNG 194
Query: 234 PGLPVSQKSWSIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINI----------- 279
L + +++ V+LP + +NL + S SLLC + ++ I
Sbjct: 195 NYLVL------LVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVE 248
Query: 280 --LVIAYCLSRARDWAWEKVK---------------FYIDVKKFPISIGIIVFSYTSQIF 322
L+I ++ V ++I + ++ I++FS+
Sbjct: 249 AALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPA 308
Query: 323 LPSLEGNMQQPSEFHCMMNWTHI---AACVLKGLFALVAYLTWADETKEVITDNLPGSIR 379
+ + ++ S MMN + I A ++ L AL YLT+ + + + +
Sbjct: 309 VLPIYEELKDRSRRR-MMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILG 367
Query: 380 AVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTL-RCA 438
+ + +V A+L A + +F S C S D W +L +
Sbjct: 368 TDILLLIVRLAVL------MAVTLTVPVVIFPIRSSVTHLLCASKD--FSWWRHSLITVS 419
Query: 439 LVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFV 498
++ FT L+ I+VP + G G+ + L F+LPS F+++L+ ++ + F+
Sbjct: 420 ILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFL 479
Query: 499 IGGICSVSG 507
+ G+ ++G
Sbjct: 480 LSGVLVMTG 488
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/372 (19%), Positives = 149/372 (40%), Gaps = 48/372 (12%)
Query: 131 GMFVLGLPYAILH-GGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAI 189
G +L P+A GG + FL+ ++V +G +++ Y G+ +Y +
Sbjct: 39 GAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILG--YAAAVSGQA-----TYQGV 91
Query: 190 ANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGN----LMYNSFPGLPVSQKSW-- 243
C P G++ ++ L+M + ++ V G+ L + G P + + W
Sbjct: 92 VRGLCGPAI----GKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYA 147
Query: 244 ------SIIATAVLLPCAFLKNLKAVSKFSLLCTLAH-FVINILVIAYCL-----SRARD 291
+++ V+LP + + + S+L TLA ++ ++ + Y L R
Sbjct: 148 DQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESH 207
Query: 292 WAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMN--WTHIAACV 349
+ + FP I F + S+ +M++ S H + + +A C+
Sbjct: 208 PSLSPASWTSVFSVFPT----ICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCL 263
Query: 350 LKGLFALVAYLTWADETKEVITDNLPGS--IRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
+ L + +LT+ E + + PG+ + V + + YP+ F L +
Sbjct: 264 IYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLF-----LGR 318
Query: 408 SLFQEGSRAFFPACYSGDGRLKSWGLTLRCAL----VVFTLLMAIYVPHFALLMGLTGSL 463
S+ Q+ R + GL +R L V TL MA+++P + ++ + G +
Sbjct: 319 SVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGI 378
Query: 464 TGAGLCFLLPSL 475
+ + F+ P L
Sbjct: 379 S-SFFIFIFPGL 389
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/301 (21%), Positives = 129/301 (42%), Gaps = 41/301 (13%)
Query: 225 SGNLMYNSFPGLPVSQKSWSIIATA------VLLPCAFLKNLKAVSKFSLLCTLAHFVIN 278
S + Y + G +K W T +LLP K+ SKF++L T++ +
Sbjct: 267 SSMIFYANDTGAQQFEKWWDKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLI 326
Query: 279 ILVI--AYCLSRARDWAWE-KVKFYI-DVK-KFPISIGIIVFSY-TSQIFLPSLEGNMQQ 332
LV A L ++ W +F++ +++ +FP G++ ++ + L+ N +Q
Sbjct: 327 FLVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIITLLKNNKKQ 386
Query: 333 PSEFHCMMNWTHIAACVLKGLFALVAYLTWA---------DETKEVITDNLPGS--IRAV 381
+ + IA ++ + + L +A D ++ DN P S + +
Sbjct: 387 ENNVRDLC----IAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFI 442
Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVV 441
IFL+ + + YPL + A L +F + +P+ + L L +V
Sbjct: 443 ARIFLLFQMMTVYPLLGYLARVQLLGHIFGD----IYPSIFHV--------LILNLIIVG 490
Query: 442 FTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWR--KLLWHQVFFDVAIFVI 499
++MA + P+ ++ +G+ G F+ PSL ++ L + +L W ++ F V I ++
Sbjct: 491 AGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKLIFHVFIIIL 550
Query: 500 G 500
G
Sbjct: 551 G 551
Score = 29.3 bits (64), Expect = 9.2
Identities = 22/109 (20%), Positives = 46/109 (42%), Gaps = 8/109 (7%)
Query: 125 VTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVR 183
+ N + G +L +P+ I G+ G+ +II ++ Y C Y + ++
Sbjct: 126 IWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLY-------CCYRVVKSRTMMFSL 178
Query: 184 DSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNS 232
D+ C F + G + ++ L+ I+Y V+ N ++N+
Sbjct: 179 DTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNT 227
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 46.2 bits (108), Expect = 7e-05
Identities = 81/411 (19%), Positives = 171/411 (41%), Gaps = 79/411 (19%)
Query: 123 WNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181
+N++NAI G +LGL YA+ + G L LFL+ A++ Y+ +L+ + VV
Sbjct: 73 FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLL-------KSSGVVG 125
Query: 182 VRDSYVAIANACCAPRFPTLGGRVVNVAQIIELV--MTCILYVVVSG-NLMYNSFPGLPV 238
+R +Y + F T G +A ++ + M+ LY++ S L+ +F L
Sbjct: 126 IR-AYEQLGYRA----FGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180
Query: 239 SQKSW--------SIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
W +++ ++LP A ++ L + S FSL C + F+I ++ + +
Sbjct: 181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSC-MVFFLIAVIYKKFHVP 239
Query: 288 --------------RARDWAWEKVKFYIDVK--------------KFPISIGIIVFSYTS 319
+ EKV+ ++ + + +I I+ F++
Sbjct: 240 CPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVC 299
Query: 320 QIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--- 374
+ + ++ PS + + N + ++ L AL YLT+ + + +
Sbjct: 300 HPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKV 359
Query: 375 -PGSIRAV-VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSW- 431
P + + V + ++ L+ P+ F +++ LF ++ F SW
Sbjct: 360 DPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFP--NQEF------------SWL 405
Query: 432 -GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
+ + L+ L+ I+ P+ + G+ G+ + L F+ P++F+ R++
Sbjct: 406 RHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIM 456
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 38/237 (16%)
Query: 121 AGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEV 179
+ +N++NAI G +LGL YA+ + G L + +++ A++ Y+ +L L E G +
Sbjct: 80 SSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLL---LKTAKEGGSL 136
Query: 180 VRVRDSYVAIANACCAPRFPTLGGRVVNVA-QIIELVMTCILYVVVSGNLMYNSFPGLPV 238
+ + A +P G V++ Q I + + + + + +F GL
Sbjct: 137 IYEKLGEKAFG-------WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEE 189
Query: 239 SQKSWSI--------IATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
+ W + ++ ++LP + LKNL + S FSL C + F +++++
Sbjct: 190 NTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMV--FFVSVVI------ 241
Query: 288 RARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTH 344
++K + + S+G + F+ T + + L N + S+ + MM++TH
Sbjct: 242 ------YKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNN-SESSDVNFMMDYTH 291
Score = 38.9 bits (89), Expect = 0.012
Identities = 45/222 (20%), Positives = 92/222 (41%), Gaps = 29/222 (13%)
Query: 298 KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFA 355
K+++ + +I I+VF++ + + ++ S + + N + V+ L A
Sbjct: 324 KYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAA 383
Query: 356 LVAYLTWADETKE--------VITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
L YLT+ E ++ V T ++P +V + ++ L+ P+ F +
Sbjct: 384 LFGYLTFYGEVEDELLHAYSKVYTLDIP---LLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440
Query: 408 SLFQEGSRAFFPACYSGDGRLKSW--GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTG 465
LF + R SW + L+ ++ I VP + G G+ +
Sbjct: 441 LLFPK--------------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSA 486
Query: 466 AGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSG 507
L F+LP++F+L+L+ ++ IF++ GI + G
Sbjct: 487 TMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIG 528
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 38/237 (16%)
Query: 121 AGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEV 179
+ +N++NAI G +LGL YA+ + G L + +++ A++ Y+ +L L E G +
Sbjct: 80 SSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLL---LKTAKEGGSL 136
Query: 180 VRVRDSYVAIANACCAPRFPTLGGRVVNVA-QIIELVMTCILYVVVSGNLMYNSFPGLPV 238
+ + A +P G V++ Q I + + + + + +F GL
Sbjct: 137 IYEKLGEKAFG-------WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEE 189
Query: 239 SQKSWSI--------IATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
+ W + ++ ++LP + LKNL + S FSL C + F +++++
Sbjct: 190 NTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMV--FFVSVVI------ 241
Query: 288 RARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTH 344
++K + + S+G + F+ T + + L N + S+ + MM++TH
Sbjct: 242 ------YKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNN-SESSDVNFMMDYTH 291
Score = 38.9 bits (89), Expect = 0.012
Identities = 45/222 (20%), Positives = 92/222 (41%), Gaps = 29/222 (13%)
Query: 298 KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFA 355
K+++ + +I I+VF++ + + ++ S + + N + V+ L A
Sbjct: 324 KYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAA 383
Query: 356 LVAYLTWADETKE--------VITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
L YLT+ E ++ V T ++P +V + ++ L+ P+ F +
Sbjct: 384 LFGYLTFYGEVEDELLHAYSKVYTLDIP---LLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440
Query: 408 SLFQEGSRAFFPACYSGDGRLKSW--GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTG 465
LF + R SW + L+ ++ I VP + G G+ +
Sbjct: 441 LLFPK--------------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSA 486
Query: 466 AGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSG 507
L F+LP++F+L+L+ ++ IF++ GI + G
Sbjct: 487 TMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIG 528
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 38.1 bits (87), Expect = 0.020
Identities = 84/434 (19%), Positives = 152/434 (35%), Gaps = 75/434 (17%)
Query: 109 GGHDKPKITAWEAGWNVTNAIQGMFVLGLPYAI-LHGGYLGLFLIIFAAVVCCYTGKILI 167
GG D+ + A + V NA G +L P A GG + +V +G +++
Sbjct: 44 GGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVIL 103
Query: 168 A-CLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSG 226
A C NE +Y + A C L G + VA + TCI ++++ G
Sbjct: 104 AYCSQASNER--------TYQEVVWAVCGK----LTGVLCEVAIAVYTFGTCIAFLIIIG 151
Query: 227 NLMYN------------SFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAH 274
+ S P + + S+ A +LP + + + S L +
Sbjct: 152 DQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGT 211
Query: 275 FVINILVIAYCLSRARDWAW-EKVKFYIDVKKFPIS-------IGIIVFSYTSQIFLPSL 326
+ + +VI + W +K ++ P S + I F + + +
Sbjct: 212 WYVTAIVII-------KYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPV 264
Query: 327 EGNMQQPSEFHCMMNWTHIAACVLKGLFA------LVAYLTWADETKEVITDNLPGSIRA 380
+MQQP + W + + A + +LT+ + + P A
Sbjct: 265 FNSMQQPE----VKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMA 320
Query: 381 VV--NIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSG------DGRLKSWG 432
V F++ L SYP+ F V+E + Y G GR +
Sbjct: 321 VAVARAFIILSVLTSYPILHFCGRAVVEGLWLR----------YQGVPVEEDVGRERRRR 370
Query: 433 LTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGA------GLCFLLPSLFHLRLLWRKLL 486
+ + TLL+A+++P ++ + G L GLC + L + +
Sbjct: 371 VLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASW 430
Query: 487 WHQVFFDVAIFVIG 500
W V + V + +G
Sbjct: 431 WVLVSYGVLLVTLG 444
>gi|112382239 desmuslin isoform B [Homo sapiens]
Length = 1253
Score = 31.2 bits (69), Expect = 2.4
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 55 RQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPL-PPSGSKDQVGGGGEFGGHDK 113
R+ L A G P + GAEAP G I ++R + L PSG + GG G
Sbjct: 1036 RESLSRQRSPAPGSPDEEGGAEAPAAG-IRFRRWATRELYIPSGESEVAGGASHSSGQRT 1094
Query: 114 PK 115
P+
Sbjct: 1095 PQ 1096
>gi|112382237 desmuslin isoform A [Homo sapiens]
Length = 1565
Score = 31.2 bits (69), Expect = 2.4
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 55 RQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPL-PPSGSKDQVGGGGEFGGHDK 113
R+ L A G P + GAEAP G I ++R + L PSG + GG G
Sbjct: 1036 RESLSRQRSPAPGSPDEEGGAEAPAAG-IRFRRWATRELYIPSGESEVAGGASHSSGQRT 1094
Query: 114 PK 115
P+
Sbjct: 1095 PQ 1096
>gi|44662807 hypothetical protein LOC388407 [Homo sapiens]
Length = 251
Score = 31.2 bits (69), Expect = 2.4
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 97 GSKDQVGGGGEFGGHDKPKITAW--EAGW---NVTNAIQGMFVLGLPYAILHGGYLGLFL 151
G+ +GG G P +A+ EAG NV+ +G F LGLP+ + G YL L L
Sbjct: 71 GAPALLGGSPSSGSPGHPPGSAFGVEAGCRALNVSEHARGGFALGLPFGLSGGAYLFLLL 130
>gi|84662753 G protein-coupled receptor 149 [Homo sapiens]
Length = 731
Score = 30.8 bits (68), Expect = 3.2
Identities = 19/59 (32%), Positives = 24/59 (40%)
Query: 419 PACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
P C G WG + C+ L +Y F LL+GL+ LT LC P H
Sbjct: 168 PLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLH 226
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 30.0 bits (66), Expect = 5.4
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 6/48 (12%)
Query: 69 PCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKI 116
P G G E P+ RG P P SG K + G GE G H P +
Sbjct: 619 PMGQRGREGPMG-----PRGEAGP-PGSGEKGERGAAGEPGPHGPPGV 660
>gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo
sapiens]
Length = 1543
Score = 29.6 bits (65), Expect = 7.1
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 430 SWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
SWGLT C + + ++ MA+ + ++ TG + F L SL+ L L+
Sbjct: 179 SWGLTYICFIFIMSIFMALVITSIPIVFH-----TGFMVIFTLYSLYGLSLI 225
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 29.3 bits (64), Expect = 9.2
Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 6/54 (11%)
Query: 3 TLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQ 56
TL SKL S+ NK +M G + R+GF + F D+ +F +++
Sbjct: 1769 TLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSK------FGDLDEQEFVYKE 1816
>gi|157388943 transmembrane protein 104 [Homo sapiens]
Length = 496
Score = 29.3 bits (64), Expect = 9.2
Identities = 49/251 (19%), Positives = 93/251 (37%), Gaps = 35/251 (13%)
Query: 246 IATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKK 305
I T +L P F +++ +L +L ++ ++I L R E D
Sbjct: 214 IFTLLLGPFTFF-DVQKTKYLQILTSLMRWIAFAVMIVLALIRIGHGQGEGHPPLADFSG 272
Query: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW-AD 364
G+ V+S+ Q LPSL + ++ ++ GL + A + D
Sbjct: 273 VRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGD 332
Query: 365 ETKEVITDNLP-------GSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGS--- 414
++ T N ++R + +F V ++P+ + +EG
Sbjct: 333 SLMDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYP 392
Query: 415 ----RAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCF 470
R FP +TL V +L+A L+G+TG+ G G+ +
Sbjct: 393 WVVDRVVFPT------------ITL-----VPPVLVAFCTHDLESLVGITGAYAGTGIQY 435
Query: 471 LLPS--LFHLR 479
++P+ ++H R
Sbjct: 436 VIPAFLVYHCR 446
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,424,772
Number of Sequences: 37866
Number of extensions: 897472
Number of successful extensions: 2790
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2753
Number of HSP's gapped (non-prelim): 33
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.