Guide to the Human Genome
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Search of human proteins with 169210082

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169210082 PREDICTED: similar to coiled-coil domain
containing 25 [Homo sapiens]
         (170 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169210521 PREDICTED: similar to coiled-coil domain containing...   351   2e-97
gi|169210082 PREDICTED: similar to coiled-coil domain containing...   351   2e-97
gi|169209444 PREDICTED: similar to coiled-coil domain containing...   289   9e-79
gi|108936950 coiled-coil domain containing 25 [Homo sapiens]          244   3e-65
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    29   2.2  
gi|218505670 epithelial cell adhesion molecule precursor [Homo s...    28   2.9  
gi|115527120 nebulin [Homo sapiens]                                    28   3.8  
gi|4507531 toll-like receptor 3 [Homo sapiens]                         28   5.0  
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho...    28   5.0  
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    27   6.5  
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    27   6.5  
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              27   6.5  
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             27   6.5  
gi|4758666 LATS homolog 1 [Homo sapiens]                               27   6.5  
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]                     27   8.5  
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    27   8.5  
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    27   8.5  
gi|38373673 synaptonemal complex protein 2 [Homo sapiens]              27   8.5  

>gi|169210521 PREDICTED: similar to coiled-coil domain containing 25
           [Homo sapiens]
          Length = 170

 Score =  351 bits (900), Expect = 2e-97
 Identities = 170/170 (100%), Positives = 170/170 (100%)

Query: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
           MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI
Sbjct: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60

Query: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120
           EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT
Sbjct: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120

Query: 121 MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV 170
           MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV
Sbjct: 121 MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV 170


>gi|169210082 PREDICTED: similar to coiled-coil domain containing 25
           [Homo sapiens]
          Length = 170

 Score =  351 bits (900), Expect = 2e-97
 Identities = 170/170 (100%), Positives = 170/170 (100%)

Query: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
           MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI
Sbjct: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60

Query: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120
           EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT
Sbjct: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120

Query: 121 MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV 170
           MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV
Sbjct: 121 MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVPSCRLGLLV 170


>gi|169209444 PREDICTED: similar to coiled-coil domain containing 25
           [Homo sapiens]
          Length = 173

 Score =  289 bits (739), Expect = 9e-79
 Identities = 142/153 (92%), Positives = 144/153 (94%)

Query: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
           MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI
Sbjct: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60

Query: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120
           EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT
Sbjct: 61  EDIPKEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVT 120

Query: 121 MEKKVNEILNRLEKTKVEPEKTAYEFWKREFQK 153
           MEKKVNEILNRLEKTKVEP   A++     F K
Sbjct: 121 MEKKVNEILNRLEKTKVEPGTMAHKKQHMSFGK 153


>gi|108936950 coiled-coil domain containing 25 [Homo sapiens]
          Length = 208

 Score =  244 bits (622), Expect = 3e-65
 Identities = 122/139 (87%), Positives = 127/139 (91%), Gaps = 1/139 (0%)

Query: 1   MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
           MVFYFTSSSVNSSA  IYMGKDKYENEDL+KHGWPE IWF  D+LS AHVYL+LHKGENI
Sbjct: 1   MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60

Query: 61  EDIPKEVLTDCAHLVKANSTQGCK-NNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIV 119
           EDIPKEVL DCAHLVKANS QGCK NNVNVV TP SNLKKTAD+DV QIGFHRQKDVKIV
Sbjct: 61  EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120

Query: 120 TMEKKVNEILNRLEKTKVE 138
           T+EKKVNEILNRLEKTKVE
Sbjct: 121 TVEKKVNEILNRLEKTKVE 139


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 28.9 bits (63), Expect = 2.2
 Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 65  KEVLTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVTMEKK 124
           KEVL       K  + +  ++    V    ++L +  ++    I + ++K  + +  EKK
Sbjct: 759 KEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKK 818

Query: 125 -VNEILNRLEKTKVEPE 140
            V ++ NRL K K E E
Sbjct: 819 KVQDLENRLTKQKEELE 835


>gi|218505670 epithelial cell adhesion molecule precursor [Homo
           sapiens]
          Length = 314

 Score = 28.5 bits (62), Expect = 2.9
 Identities = 18/62 (29%), Positives = 39/62 (62%), Gaps = 4/62 (6%)

Query: 84  KNNVNVVNTPRSNLKKTA-DVDVRQIGFHRQKDVKIVTM--EKKVNEILNRLEKTKVEPE 140
           +NNV  ++  +++ +KT  DVD+  + ++ +KDVK  ++   KK++  +N  E+  ++P 
Sbjct: 187 ENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNG-EQLDLDPG 245

Query: 141 KT 142
           +T
Sbjct: 246 QT 247


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 15/66 (22%)

Query: 89   VVNTPRSNLKKTADVDVRQI----GFHRQKD-----------VKIVTMEKKVNEILNRLE 133
            VV+ PR  L KTA   + QI     + + KD           ++   + K++++IL +LE
Sbjct: 5420 VVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLE 5479

Query: 134  KTKVEP 139
              K +P
Sbjct: 5480 YNKAKP 5485


>gi|4507531 toll-like receptor 3 [Homo sapiens]
          Length = 904

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 16/70 (22%), Positives = 28/70 (40%)

Query: 68  LTDCAHLVKANSTQGCKNNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIVTMEKKVNE 127
           + DC+HL           N+ V+N   + L++    +  +       DV   T+ K   E
Sbjct: 34  VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93

Query: 128 ILNRLEKTKV 137
           +  +L   KV
Sbjct: 94  LCQKLPMLKV 103


>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
           sapiens]
          Length = 370

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 31  KHGWPEYIWFRADRLS-LAHVYLQLHKGENIEDIPKEVLTDCAHLVKANSTQG 82
           KH W E+  +R  RL  LA    +  +G+++  +P E+   C+ L   NS+ G
Sbjct: 210 KH-WMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDENSSAG 261


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 14/46 (30%), Positives = 21/46 (45%)

Query: 91   NTPRSNLKKTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTK 136
            N     ++  + +D       RQKD KI   E+K   I+  LEK +
Sbjct: 1171 NLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDR 1216


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 14/46 (30%), Positives = 21/46 (45%)

Query: 91   NTPRSNLKKTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTK 136
            N     ++  + +D       RQKD KI   E+K   I+  LEK +
Sbjct: 1171 NLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDR 1216


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 15/58 (25%), Positives = 27/58 (46%)

Query: 93  PRSNLKKTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTKVEPEKTAYEFWKRE 150
           P    +K  D+D+ Q         K+   E+K +E+  + EK   + ++T  E  K+E
Sbjct: 214 PDFTYRKRLDLDLTQFVDICIDQAKLEEFEEKASELYKKFEKEFTDHQETQAELQKKE 271


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 15/58 (25%), Positives = 27/58 (46%)

Query: 93  PRSNLKKTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTKVEPEKTAYEFWKRE 150
           P    +K  D+D+ Q         K+   E+K +E+  + EK   + ++T  E  K+E
Sbjct: 477 PDFTYRKRLDLDLTQFVDICIDQAKLEEFEEKASELYKKFEKEFTDHQETQAELQKKE 534


>gi|4758666 LATS homolog 1 [Homo sapiens]
          Length = 1130

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 15/41 (36%), Positives = 19/41 (46%)

Query: 122  EKKVNEILNRLEKTKVEPEKTAYEFWKREFQKIVGFSIHVP 162
            E+ VN+ LN   K    PE   YEF  R F    G+  + P
Sbjct: 1054 EENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYP 1094


>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
          Length = 347

 Score = 26.9 bits (58), Expect = 8.5
 Identities = 17/88 (19%), Positives = 44/88 (50%), Gaps = 12/88 (13%)

Query: 86  NVNVVNTPRSNLKKTADVDVRQIGFHRQK--------DVKIVTM----EKKVNEILNRLE 133
           ++NV  T    L+   D D+++IG H +K        D K   +    +++V + + + E
Sbjct: 132 DINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFE 191

Query: 134 KTKVEPEKTAYEFWKREFQKIVGFSIHV 161
           ++K   E++ + F + + +++   ++ +
Sbjct: 192 ESKELAERSMFNFLENDVEQVSQLAVFI 219


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 26.9 bits (58), Expect = 8.5
 Identities = 13/43 (30%), Positives = 26/43 (60%)

Query: 99  KTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTKVEPEK 141
           +T  + +++  F ++KD  +  +EKK+ ++ N L K + E EK
Sbjct: 246 ETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEK 288


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 26.9 bits (58), Expect = 8.5
 Identities = 13/43 (30%), Positives = 26/43 (60%)

Query: 99  KTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTKVEPEK 141
           +T  + +++  F ++KD  +  +EKK+ ++ N L K + E EK
Sbjct: 391 ETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEK 433


>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
          Length = 1530

 Score = 26.9 bits (58), Expect = 8.5
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 99   KTADVDVRQIGFHRQKDVKIVTMEKKVNEILNRLEKTKVEP------EKTAYEFWKREFQ 152
            KTA   +R +  H+ +D +I  ++K    I+  LE  + +       EK   +FW++ FQ
Sbjct: 1390 KTAQQHLRTMN-HQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQ 1448

Query: 153  KIVGF 157
            K   +
Sbjct: 1449 KFSAY 1453


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,049,739
Number of Sequences: 37866
Number of extensions: 239767
Number of successful extensions: 760
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 747
Number of HSP's gapped (non-prelim): 20
length of query: 170
length of database: 18,247,518
effective HSP length: 95
effective length of query: 75
effective length of database: 14,650,248
effective search space: 1098768600
effective search space used: 1098768600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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