Search of human proteins with 169160863

Search of human proteins with 169160863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169160863 PREDICTED: similar to guanylate-binding protein 5
[Homo sapiens]
         (112 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169160863 PREDICTED: similar to guanylate-binding protein 5 [...   226   2e-60
gi|157671915 guanylate binding protein family, member 6 [Homo sa...   109   4e-25
gi|148234215 guanylate binding protein 4-like [Homo sapiens]          102   9e-23
gi|31377634 guanylate binding protein 4 [Homo sapiens]                102   9e-23
gi|197333737 guanylate-binding protein 5 [Homo sapiens]                77   4e-15
gi|16418425 guanylate-binding protein 5 [Homo sapiens]                 77   4e-15
gi|38327558 guanylate binding protein 2, interferon-inducible [H...    74   3e-14
gi|112382372 guanylate binding protein 3 [Homo sapiens]                70   4e-13
gi|166706903 guanylate binding protein 1, interferon-inducible, ...    70   5e-13
gi|157042792 coiled-coil domain containing 64B [Homo sapiens]          28   1.6  
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]                  27   2.7  
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]                  27   2.7  
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]                   27   2.7  
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]                   27   2.7  
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    27   4.6  
gi|33188443 microfilament and actin filament cross-linker protei...    26   6.0  
gi|33188445 microfilament and actin filament cross-linker protei...    26   6.0  
gi|38455391 ribonuclease H2, large subunit [Homo sapiens]              26   7.8  

>gi|169160863 PREDICTED: similar to guanylate-binding protein 5
           [Homo sapiens]
          Length = 112

 Score =  226 bits (577), Expect = 2e-60
 Identities = 112/112 (100%), Positives = 112/112 (100%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGEN 60
           MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGEN
Sbjct: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGEN 60

Query: 61  QEFQKKLMSHWGKMTNKTVKVCLVETAILKNALMVTGMHVSTVDQEKNNHTL 112
           QEFQKKLMSHWGKMTNKTVKVCLVETAILKNALMVTGMHVSTVDQEKNNHTL
Sbjct: 61  QEFQKKLMSHWGKMTNKTVKVCLVETAILKNALMVTGMHVSTVDQEKNNHTL 112


>gi|157671915 guanylate binding protein family, member 6 [Homo
           sapiens]
          Length = 633

 Score =  109 bits (273), Expect = 4e-25
 Identities = 54/69 (78%), Positives = 62/69 (89%), Gaps = 1/69 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           +TLAQRENS A+QRAA++YSQQMAQR++ PTD LQELLDMH ACEREAIA+FMEHS + E
Sbjct: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375

Query: 60  NQEFQKKLM 68
           NQEFQKK M
Sbjct: 376 NQEFQKKFM 384


>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
          Length = 638

 Score =  102 bits (253), Expect = 9e-23
 Identities = 51/67 (76%), Positives = 60/67 (89%), Gaps = 1/67 (1%)

Query: 3   LAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGENQ 61
           LAQ ENS A+QRAANHYSQQMAQ++RFPTD LQELLD+H  CEREAIAVFME+S + ++Q
Sbjct: 318 LAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAVCEREAIAVFMEYSFKDKSQ 377

Query: 62  EFQKKLM 68
           EFQKKL+
Sbjct: 378 EFQKKLV 384


>gi|31377634 guanylate binding protein 4 [Homo sapiens]
          Length = 640

 Score =  102 bits (253), Expect = 9e-23
 Identities = 51/67 (76%), Positives = 58/67 (86%), Gaps = 1/67 (1%)

Query: 3   LAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGENQ 61
           LAQ EN  A+QRAA+HYSQQMAQ++R PTD LQELLD+H ACEREAIAVFMEHS + EN 
Sbjct: 333 LAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENH 392

Query: 62  EFQKKLM 68
           EFQKKL+
Sbjct: 393 EFQKKLV 399


>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
          Length = 586

 Score = 76.6 bits (187), Expect = 4e-15
 Identities = 38/68 (55%), Positives = 51/68 (75%), Gaps = 1/68 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           + LAQRENS A+Q+A  HY QQM Q+++ P + LQELLD+H   EREAI VFM++S +  
Sbjct: 315 LALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEVFMKNSFKDV 374

Query: 60  NQEFQKKL 67
           +Q FQK+L
Sbjct: 375 DQSFQKEL 382


>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
          Length = 586

 Score = 76.6 bits (187), Expect = 4e-15
 Identities = 38/68 (55%), Positives = 51/68 (75%), Gaps = 1/68 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           + LAQRENS A+Q+A  HY QQM Q+++ P + LQELLD+H   EREAI VFM++S +  
Sbjct: 315 LALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEVFMKNSFKDV 374

Query: 60  NQEFQKKL 67
           +Q FQK+L
Sbjct: 375 DQSFQKEL 382


>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
           sapiens]
          Length = 591

 Score = 73.6 bits (179), Expect = 3e-14
 Identities = 37/68 (54%), Positives = 51/68 (75%), Gaps = 1/68 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           + LAQ ENS A+++A  HY QQM Q+++ PT+ LQELLD+H   EREAI VFM++S +  
Sbjct: 315 LALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDV 374

Query: 60  NQEFQKKL 67
           +Q FQ+KL
Sbjct: 375 DQMFQRKL 382


>gi|112382372 guanylate binding protein 3 [Homo sapiens]
          Length = 595

 Score = 70.1 bits (170), Expect = 4e-13
 Identities = 36/74 (48%), Positives = 50/74 (67%), Gaps = 1/74 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           + LAQ ENS A+Q+A  HY QQM Q+++ P + LQELLD+H   EREA  V+M++S +  
Sbjct: 315 LALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEVYMKNSFKDV 374

Query: 60  NQEFQKKLMSHWGK 73
           +  FQKKL +   K
Sbjct: 375 DHLFQKKLAAQLDK 388


>gi|166706903 guanylate binding protein 1, interferon-inducible,
           67kDa [Homo sapiens]
          Length = 592

 Score = 69.7 bits (169), Expect = 5e-13
 Identities = 37/74 (50%), Positives = 50/74 (67%), Gaps = 1/74 (1%)

Query: 1   MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
           + LAQ ENS A+Q+A  HY QQM Q+++ PT+ LQELLD+H   EREAI VF+  S +  
Sbjct: 317 LALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDV 376

Query: 60  NQEFQKKLMSHWGK 73
           +  FQK+L +   K
Sbjct: 377 DHLFQKELAAQLEK 390


>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
          Length = 508

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 6   RENSVALQRAANH---YSQQMAQRMRFPTDMLQELLDMHTACEREAIA-----VFMEHSR 57
           RE + AL   +      SQQ+AQ  +   ++ +EL  +   C+ +A+A       +E  +
Sbjct: 144 RERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQ 203

Query: 58  GENQEFQKK 66
           GENQ  Q +
Sbjct: 204 GENQMLQSR 212


>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
          Length = 1015

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 9/68 (13%)

Query: 6   RENSVALQRAANHYSQQMAQRMRFPT-----DMLQELLDMHTACEREAIAVFMEHSRGEN 60
           +E+    +RAA  YS   AQ+ R  +     D LQE L +HT  + + I   +E    EN
Sbjct: 240 QEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL-LHTQLKYQRI---LERLEKEN 295

Query: 61  QEFQKKLM 68
           +E +K ++
Sbjct: 296 KELRKLVL 303


>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
          Length = 997

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 9/68 (13%)

Query: 6   RENSVALQRAANHYSQQMAQRMRFPT-----DMLQELLDMHTACEREAIAVFMEHSRGEN 60
           +E+    +RAA  YS   AQ+ R  +     D LQE L +HT  + + I   +E    EN
Sbjct: 222 QEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL-LHTQLKYQRI---LERLEKEN 277

Query: 61  QEFQKKLM 68
           +E +K ++
Sbjct: 278 KELRKLVL 285


>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
          Length = 979

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 9/68 (13%)

Query: 6   RENSVALQRAANHYSQQMAQRMRFPT-----DMLQELLDMHTACEREAIAVFMEHSRGEN 60
           +E+    +RAA  YS   AQ+ R  +     D LQE L +HT  + + I   +E    EN
Sbjct: 204 QEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL-LHTQLKYQRI---LERLEKEN 259

Query: 61  QEFQKKLM 68
           +E +K ++
Sbjct: 260 KELRKLVL 267


>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
          Length = 961

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 9/68 (13%)

Query: 6   RENSVALQRAANHYSQQMAQRMRFPT-----DMLQELLDMHTACEREAIAVFMEHSRGEN 60
           +E+    +RAA  YS   AQ+ R  +     D LQE L +HT  + + I   +E    EN
Sbjct: 186 QEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL-LHTQLKYQRI---LERLEKEN 241

Query: 61  QEFQKKLM 68
           +E +K ++
Sbjct: 242 KELRKLVL 249


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 8/50 (16%)

Query: 13  QRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGENQE 62
           Q A   Y QQ AQ  +F          +H A ++ AIA F   S+G +Q+
Sbjct: 484 QPAGTFYQQQQAQTQQFQA--------VHPATQQPAIAQFPVVSQGGSQQ 525


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 2/69 (2%)

Query: 4    AQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGENQEF 63
            A R N +    A+    QQM   +R   D  Q        C   A    ++    EN+EF
Sbjct: 3222 ADRINRLQAALASTQQFQQMFDELRTWLDDKQS--QQAKNCPISAKLERLQSQLQENEEF 3279

Query: 64   QKKLMSHWG 72
            QK L  H G
Sbjct: 3280 QKSLNQHSG 3288


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 2/69 (2%)

Query: 4    AQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHSRGENQEF 63
            A R N +    A+    QQM   +R   D  Q        C   A    ++    EN+EF
Sbjct: 2720 ADRINRLQAALASTQQFQQMFDELRTWLDDKQS--QQAKNCPISAKLERLQSQLQENEEF 2777

Query: 64   QKKLMSHWG 72
            QK L  H G
Sbjct: 2778 QKSLNQHSG 2786


>gi|38455391 ribonuclease H2, large subunit [Homo sapiens]
          Length = 299

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 13/30 (43%), Positives = 18/30 (60%)

Query: 42  TACEREAIAVFMEHSRGENQEFQKKLMSHW 71
           T  E+EA  V  E S  ENQE  +K+ S++
Sbjct: 243 TILEKEAEDVIWEDSASENQEGLRKITSYF 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.125    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,445,039
Number of Sequences: 37866
Number of extensions: 114224
Number of successful extensions: 336
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 322
Number of HSP's gapped (non-prelim): 20
length of query: 112
length of database: 18,247,518
effective HSP length: 82
effective length of query: 30
effective length of database: 15,142,506
effective search space: 454275180
effective search space used: 454275180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.