Search of human proteins with 110671329

Search of human proteins with 110671329

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110671329 dihydrolipoamide branched chain transacylase
precursor [Homo sapiens]
         (482 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110671329 dihydrolipoamide branched chain transacylase precur...   964   0.0  
gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]       154   2e-37
gi|203098753 pyruvate dehydrogenase complex, component X isoform...   150   2e-36
gi|203098816 pyruvate dehydrogenase complex, component X isoform...   146   4e-35
gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component...   145   1e-34
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr...    40   0.004
gi|119120861 formin-like 3 isoform 2 [Homo sapiens]                    35   0.12 
gi|119120874 formin-like 3 isoform 1 [Homo sapiens]                    35   0.12 
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ...    33   0.58 
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide...    33   0.58 
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]       32   0.98 
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]           32   0.98 
gi|116292174 fidgetin-like 2 [Homo sapiens]                            32   1.3  
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    31   2.2  
gi|153792074 proline rich 12 [Homo sapiens]                            31   2.9  
gi|239735569 grainyhead-like 1 [Homo sapiens]                          30   3.7  
gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sap...    30   3.7  
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           30   3.7  
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           30   3.7  
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]      30   3.7  
gi|4758666 LATS homolog 1 [Homo sapiens]                               30   3.7  
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    30   4.9  
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    30   4.9  
gi|56118234 proline rich 6 [Homo sapiens]                              30   4.9  
gi|15812226 transcriptional regulating factor 1 [Homo sapiens]         30   4.9  
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     30   6.4  
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     30   6.4  
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    30   6.4  
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    30   6.4  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    30   6.4  

>gi|110671329 dihydrolipoamide branched chain transacylase precursor
           [Homo sapiens]
          Length = 482

 Score =  964 bits (2491), Expect = 0.0
 Identities = 482/482 (100%), Positives = 482/482 (100%)

Query: 1   MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAAL 60
           MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAAL
Sbjct: 1   MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAAL 60

Query: 61  RGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKK 120
           RGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKK
Sbjct: 61  RGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKK 120

Query: 121 LYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRL 180
           LYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRL
Sbjct: 121 LYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRL 180

Query: 181 AMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPIL 240
           AMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPIL
Sbjct: 181 AMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPIL 240

Query: 241 VSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFA 300
           VSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFA
Sbjct: 241 VSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFA 300

Query: 301 RGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVK 360
           RGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVK
Sbjct: 301 RGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVK 360

Query: 361 NVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAI 420
           NVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAI
Sbjct: 361 NVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAI 420

Query: 421 GALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLD 480
           GALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLD
Sbjct: 421 GALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLD 480

Query: 481 LK 482
           LK
Sbjct: 481 LK 482


>gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]
          Length = 647

 Score =  154 bits (388), Expect = 2e-37
 Identities = 127/437 (29%), Positives = 211/437 (48%), Gaps = 60/437 (13%)

Query: 80  TVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYY--NLDDIAYVGKPL-V 136
           TV+ W  K G+ +S+ D + E+++DKA++    + +G + K+       D+  +G PL +
Sbjct: 234 TVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVP-LGTPLCI 292

Query: 137 DIETEALKDSEEDVVET--------------PAVSHDEHTHQEI---------------K 167
            +E EA   +  D   T              P V+    T Q +               K
Sbjct: 293 IVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPK 352

Query: 168 GRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMP 227
           GR    +P  ++LA+E  I L++V G+G DGRI K+DI +++  +      P+P   + P
Sbjct: 353 GR-VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVA----PAPAAVVPP 407

Query: 228 PPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMV-KTMSAALKIPHFGYCDEIDLTE 286
             P              PV TG     PI   ++ +  + M +   IPH+    ++++ E
Sbjct: 408 TGP-----------GMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGE 456

Query: 287 LVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASH--NI 344
           ++ +R+EL  I   R  K+S   F +KA++L  L+ P  N+S      +   + +H  ++
Sbjct: 457 VLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSS----WMDTVIRQNHVVDV 511

Query: 345 GIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSI 404
            +A+ T  GLI P V N  I  +  IA ++  L       +L   +  GGTFT+SN+G  
Sbjct: 512 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 571

Query: 405 GGTFAKPVIMPPEVAIGALGSI--KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSR 462
           G      +I PP+  I A+G+   K +P  N+KG    A +M+V+ S DHRV+DGA  ++
Sbjct: 572 GIKNFSAIINPPQACILAIGASEDKLVPADNEKG-FDVASMMSVTLSCDHRVVDGAVGAQ 630

Query: 463 FSNLWKSYLENPAFMLL 479
           +   ++ YLE P  MLL
Sbjct: 631 WLAEFRKYLEKPITMLL 647



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 16/42 (38%), Positives = 26/42 (61%)

Query: 80  TVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKL 121
           T+  W  KEGD +++ D I EV++DKA+V   S  +  + K+
Sbjct: 107 TIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKI 148


>gi|203098753 pyruvate dehydrogenase complex, component X isoform 1
           [Homo sapiens]
          Length = 501

 Score =  150 bits (380), Expect = 2e-36
 Identities = 121/457 (26%), Positives = 214/457 (46%), Gaps = 45/457 (9%)

Query: 56  TTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYD 115
           +T  LRG  ++  +  +   + E  + +W  KEG+ VS  D++CE+++DKA VT+ +  D
Sbjct: 48  STQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDD 107

Query: 116 GVIKKLYY-----NLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTH------- 163
           G++ K+       N+   + +G  + + E     +  +DV   P VS             
Sbjct: 108 GILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQI 167

Query: 164 ------QEIKGR-KTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLE-KQTGA 215
                 + I G  +   +PA R +  ++++  S+   +G  G   KED L  ++ KQTG 
Sbjct: 168 SIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGK 227

Query: 216 ILP--PSPKVEIMPPPPKPKDMTV----------PILVSKPPVFTGKDKTEPIKGFQKAM 263
           I    P+P     P  P P   T           P+     P   G     P    ++ +
Sbjct: 228 ITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVI 287

Query: 264 VKTMSAALK-IPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQF 322
            K ++ +   +PH     + DL  ++K+R++L        IK+S   F +KAA++ L Q 
Sbjct: 288 AKRLTESKSTVPHAYATADCDLGAVLKVRQDL----VKDDIKVSVNDFIIKAAAVTLKQM 343

Query: 323 PILNASVD-ENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLG 381
           P +N S D E  + + +    +I +A+ T++GL+ P +K+     I +IA  +  L K  
Sbjct: 344 PDVNVSWDGEGPKQLPFI---DISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKA 400

Query: 382 SVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGE---- 437
              +L   +  GG+F++SN+G  G      VI PP+  I A+G  + + +  +  E    
Sbjct: 401 RDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAK 460

Query: 438 VYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENP 474
           + + Q++ V+ S+D RV+D    +RF   +K+ LENP
Sbjct: 461 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497


>gi|203098816 pyruvate dehydrogenase complex, component X isoform 2
           [Homo sapiens]
          Length = 486

 Score =  146 bits (369), Expect = 4e-35
 Identities = 118/451 (26%), Positives = 210/451 (46%), Gaps = 45/451 (9%)

Query: 62  GQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKL 121
           G  ++  +  +   + E  + +W  KEG+ VS  D++CE+++DKA VT+ +  DG++ K+
Sbjct: 39  GDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKI 98

Query: 122 YY-----NLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTH------------- 163
                  N+   + +G  + + E     +  +DV   P VS                   
Sbjct: 99  VVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKK 158

Query: 164 QEIKGR-KTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLE-KQTGAILP--P 219
           + I G  +   +PA R +  ++++  S+   +G  G   KED L  ++ KQTG I    P
Sbjct: 159 EHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRP 218

Query: 220 SPKVEIMPPPPKPKDMTV----------PILVSKPPVFTGKDKTEPIKGFQKAMVKTMSA 269
           +P     P  P P   T           P+     P   G     P    ++ + K ++ 
Sbjct: 219 TPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTE 278

Query: 270 ALK-IPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNAS 328
           +   +PH     + DL  ++K+R++L        IK+S   F +KAA++ L Q P +N S
Sbjct: 279 SKSTVPHAYATADCDLGAVLKVRQDL----VKDDIKVSVNDFIIKAAAVTLKQMPDVNVS 334

Query: 329 VD-ENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLS 387
            D E  + + +    +I +A+ T++GL+ P +K+     I +IA  +  L K     +L 
Sbjct: 335 WDGEGPKQLPFI---DISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLL 391

Query: 388 TTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGE----VYKAQI 443
             +  GG+F++SN+G  G      VI PP+  I A+G  + + +  +  E    + + Q+
Sbjct: 392 PEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQL 451

Query: 444 MNVSWSADHRVIDGATMSRFSNLWKSYLENP 474
           + V+ S+D RV+D    +RF   +K+ LENP
Sbjct: 452 ITVTMSSDSRVVDDELATRFLKSFKANLENP 482


>gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component of
           2-oxo-glutarate complex) [Homo sapiens]
          Length = 453

 Score =  145 bits (365), Expect = 1e-34
 Identities = 118/445 (26%), Positives = 190/445 (42%), Gaps = 66/445 (14%)

Query: 53  FLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITS 112
           F +TTA  +  +V  K     E + E  V+ W    GDTV++ + +CE+++DK SV + S
Sbjct: 59  FFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEVVCEIETDKTSVQVPS 117

Query: 113 RYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTL 172
             +GVI+ L          G PL  +       ++    E PA                 
Sbjct: 118 PANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAA---------------- 161

Query: 173 ATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEI-MPPPPK 231
           A P                                  E    A+ PP+  +   MPP P 
Sbjct: 162 AAPKA--------------------------------EPTAAAVPPPAAPIPTQMPPVPS 189

Query: 232 PKDMTV--PILVSKPPVFTGKDKTEPIKGF------------QKAMVKTMSAALKIPHFG 277
           P       P+   KP V     +    KG             Q+   +   A        
Sbjct: 190 PSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLT 249

Query: 278 YCDEIDLTELVKLREELKPIAFAR-GIKLSFMPFFLKAASLGLLQFPILNASVDENCQNI 336
             +EID++ + ++R   K     +  +KL FM  F+KA++  L + P++NA +D+  + +
Sbjct: 250 TFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEV 309

Query: 337 TYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTF 396
            Y+   +I +A+ T +GL+VP ++NV+  +  DI   +  L +    ++L+  D+ GGTF
Sbjct: 310 VYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTF 369

Query: 397 TLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVID 456
           T+SN G  G  F  P+I PP+ AI  +  I   P     G+V    +M V+ + DHR+ID
Sbjct: 370 TISNGGVFGSLFGTPIINPPQSAILGMHGIFDRP-VAIGGKVEVRPMMYVALTYDHRLID 428

Query: 457 GATMSRFSNLWKSYLENPAFMLLDL 481
           G     F    K+ +E+P  +LLDL
Sbjct: 429 GREAVTFLRKIKAAVEDPRVLLLDL 453


>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
           precursor [Homo sapiens]
          Length = 725

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/70 (34%), Positives = 36/70 (51%)

Query: 80  TVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIE 139
           T+++ +VK GD V   DS+  + + K   TI S  DG +KK++Y     A    PLV+ E
Sbjct: 656 TIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFE 715

Query: 140 TEALKDSEED 149
            E     E +
Sbjct: 716 EEESDKRESE 725


>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
          Length = 976

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 19/156 (12%)

Query: 124 NLDDIAYVGKPLV--DIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLA 181
           N+  +A + K L+  + E E++K++ E+       SH  HT + +   K  A    RR  
Sbjct: 368 NMMRVAELEKQLLQREKELESIKETYENT------SHQVHTLRRLIKEKEEAFQ--RRCH 419

Query: 182 MENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSP---KVEIMPPPPKPKDMTVP 238
           +E N++  E V S    R+   ++   +      +L P+P   +V  +PPPP P     P
Sbjct: 420 LEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAP-----P 474

Query: 239 ILVSKPPVFTGKDKTEPIKGFQKAMVKTMS-AALKI 273
           +    PP+        P+ G   ++V T+  +A++I
Sbjct: 475 LPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRI 510


>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
          Length = 1027

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 19/156 (12%)

Query: 124 NLDDIAYVGKPLV--DIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLA 181
           N+  +A + K L+  + E E++K++ E+       SH  HT + +   K  A    RR  
Sbjct: 419 NMMRVAELEKQLLQREKELESIKETYENT------SHQVHTLRRLIKEKEEAFQ--RRCH 470

Query: 182 MENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSP---KVEIMPPPPKPKDMTVP 238
           +E N++  E V S    R+   ++   +      +L P+P   +V  +PPPP P     P
Sbjct: 471 LEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAP-----P 525

Query: 239 ILVSKPPVFTGKDKTEPIKGFQKAMVKTMS-AALKI 273
           +    PP+        P+ G   ++V T+  +A++I
Sbjct: 526 LPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRI 561


>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform a precursor [Homo sapiens]
          Length = 728

 Score = 33.1 bits (74), Expect = 0.58
 Identities = 16/54 (29%), Positives = 29/54 (53%)

Query: 86  VKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIE 139
           VK GD V++   IC +++ K   ++T+   G +K ++    D    G  LV++E
Sbjct: 675 VKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 728


>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform b [Homo sapiens]
          Length = 702

 Score = 33.1 bits (74), Expect = 0.58
 Identities = 16/54 (29%), Positives = 29/54 (53%)

Query: 86  VKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIE 139
           VK GD V++   IC +++ K   ++T+   G +K ++    D    G  LV++E
Sbjct: 649 VKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 702


>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
          Length = 1439

 Score = 32.3 bits (72), Expect = 0.98
 Identities = 14/30 (46%), Positives = 19/30 (63%), Gaps = 4/30 (13%)

Query: 218 PPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
           PP P ++ +PPPP P ++ VP     PPVF
Sbjct: 861 PPPPLLDSIPPPPVPGNLLVP----PPPVF 886


>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
          Length = 788

 Score = 32.3 bits (72), Expect = 0.98
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 13/107 (12%)

Query: 83  EWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY--------YNLDDIAYVGKP 134
           E+ + +GD    FD + E  + +  +T+    D   ++LY         ++D   Y   P
Sbjct: 305 EYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGP 364

Query: 135 LVDIETEALKDSEEDVVETPAVSHDEH---THQEIKGRKTLATPAVR 178
             D  T  +K S EDV E P  S   +    H++I+    + T   R
Sbjct: 365 FKD--TTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMAR 409


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 212 QTGAILPPSPKVEIMPPPPKP 232
           QTGA LPP P   ++ PPP P
Sbjct: 174 QTGAALPPPPPAALLQPPPPP 194


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 15/37 (40%), Positives = 19/37 (51%)

Query: 211 KQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
           K TG    P+P  + +PPPP P  +  P L   PP F
Sbjct: 539 KGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDF 575


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 209  LEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEP 255
            LE++     PP+P  +  PPPP P     P L S PP+      + P
Sbjct: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQ--PALPSPPPLVAPTPSSPP 1497


>gi|239735569 grainyhead-like 1 [Homo sapiens]
          Length = 618

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 9/91 (9%)

Query: 221 PKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCD 280
           P+VE  P P   K  ++PI+  +P +  G+++ + +K     +V      L I   G+  
Sbjct: 81  PEVE-HPEPDHSKRNSIPIVTEQPLISAGENRVQVLKNVPFNIVLPHGNQLGIDKRGHLT 139

Query: 281 EIDLTELV--------KLREELKPIAFARGI 303
             D T  V         ++ E +P  FA GI
Sbjct: 140 APDTTVTVSIATMPTHSIKTETQPHGFAVGI 170


>gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo
           sapiens]
          Length = 1124

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 18/58 (31%), Positives = 29/58 (50%)

Query: 148 EDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDI 205
           ++V E PAV  +  T    +  K    P +  +   N+IK  +V+G G  G++LK  I
Sbjct: 786 QNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARI 843


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 4/48 (8%)

Query: 211 KQTGAILPPSPKVEIMPPPPKPKDMTVPI----LVSKPPVFTGKDKTE 254
           K T A+LP  P V ++P  P P + TV +      + PPV    D  E
Sbjct: 161 KPTEAVLPSPPTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLE 208


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 4/48 (8%)

Query: 211 KQTGAILPPSPKVEIMPPPPKPKDMTVPI----LVSKPPVFTGKDKTE 254
           K T A+LP  P V ++P  P P + TV +      + PPV    D  E
Sbjct: 161 KPTEAVLPSPPTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLE 208


>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
          Length = 1164

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 17/63 (26%), Positives = 26/63 (41%)

Query: 217 LPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHF 276
           LPP P ++   PPP P  +  P+  S P       K + +K F + +       +    F
Sbjct: 588 LPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRF 647

Query: 277 GYC 279
           G C
Sbjct: 648 GPC 650


>gi|4758666 LATS homolog 1 [Homo sapiens]
          Length = 1130

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 12/28 (42%), Positives = 16/28 (57%)

Query: 218 PPSPKVEIMPPPPKPKDMTVPILVSKPP 245
           PP P+V  + PPP P+  T P   + PP
Sbjct: 237 PPPPQVRSVTPPPPPRGQTPPPRGTTPP 264


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 30/115 (26%)

Query: 141 EALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPA--VRRLAMENNIKLSEVVGSGKDG 198
           E  ++ E+   E      ++H H++IK       P+  + RL +         VG+G+D 
Sbjct: 720 EKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLR--------VGAGQDK 771

Query: 199 RILKEDILNYLEKQTGAILPPSPKVEIMP-------PPPKPKDMTVPILVSKPPV 246
            ++ + +             P+P+ +  P       PPP P     P+LVS  PV
Sbjct: 772 IVISKVV-------------PAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPV 813


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 4/53 (7%)

Query: 193 GSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPP 245
           G  K+ R + E+++   EK+    LPP P   + PP P P     P   S PP
Sbjct: 378 GEEKEERAVAEEMMPAAEKEEAK-LPPPP---LTPPAPSPPPPLPPPSTSPPP 426


>gi|56118234 proline rich 6 [Homo sapiens]
          Length = 272

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 218 PPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKI 273
           PP P++ ++PPPP P         S   +  G+ + E  + FQK    T   A K+
Sbjct: 78  PPPPELALLPPPPPPPPTPATPTSSASNLDLGEQR-ERWETFQKRQKLTSEGAAKL 132


>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
          Length = 1200

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 11/32 (34%), Positives = 18/32 (56%)

Query: 207 NYLEKQTGAILPPSPKVEIMPPPPKPKDMTVP 238
           N  +++   +LPP P+  + PPPP P    +P
Sbjct: 542 NLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLP 573


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 5/36 (13%)

Query: 215 AILPPSPKVE-----IMPPPPKPKDMTVPILVSKPP 245
           A +PP+P +      I+PPPP P D T P     PP
Sbjct: 571 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 606


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 5/36 (13%)

Query: 215 AILPPSPKVE-----IMPPPPKPKDMTVPILVSKPP 245
           A +PP+P +      I+PPPP P D T P     PP
Sbjct: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 615


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 218 PPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEP 255
           PP+P     PPP  PK+       + PPV  G+++  P
Sbjct: 792 PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPP 829


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 218 PPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEP 255
           PP+P     PPP  PK+       + PPV  G+++  P
Sbjct: 809 PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPP 846


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 3/46 (6%)

Query: 213  TGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKG 258
            T A  PPSPK  +  PPPK    T     + PP   G   T P KG
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTP---AATPPSPKGGLATPPPKG 1170


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,377,258
Number of Sequences: 37866
Number of extensions: 840769
Number of successful extensions: 4409
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4235
Number of HSP's gapped (non-prelim): 150
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.