BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] (1938 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 3760 0.0 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3159 0.0 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3146 0.0 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3146 0.0 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3141 0.0 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3138 0.0 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3070 0.0 gi|156104908 myosin heavy chain 6 [Homo sapiens] 2992 0.0 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 2977 0.0 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2544 0.0 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2311 0.0 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1388 0.0 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1387 0.0 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1387 0.0 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1387 0.0 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1375 0.0 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1374 0.0 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1262 0.0 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1258 0.0 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1245 0.0 gi|215982791 myosin VA isoform 1 [Homo sapiens] 608 e-173 gi|153945715 myosin VC [Homo sapiens] 608 e-173 gi|215982794 myosin VA isoform 2 [Homo sapiens] 605 e-172 gi|122937345 myosin VB [Homo sapiens] 582 e-165 gi|28416946 myosin 18A isoform a [Homo sapiens] 511 e-144 gi|42794779 myosin 18A isoform b [Homo sapiens] 507 e-143 gi|154354979 myosin X [Homo sapiens] 483 e-136 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 474 e-133 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 474 e-133 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 474 e-133 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 3760 bits (9750), Expect = 0.0 Identities = 1938/1938 (100%), Positives = 1938/1938 (100%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV Sbjct: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRN 240 SGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRN Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRN 240 Query: 241 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELI 300 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELI Sbjct: 241 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELI 300 Query: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH Sbjct: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360 Query: 361 YGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQ 420 YGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQ Sbjct: 361 YGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQ 420 Query: 421 QVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 480 QVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI Sbjct: 421 QVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 480 Query: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 540 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC Sbjct: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 540 Query: 541 MFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNK 600 MFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNK Sbjct: 541 MFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNK 600 Query: 601 DPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLN 660 DPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLN Sbjct: 601 DPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLN 660 Query: 661 KLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYA 720 KLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYA Sbjct: 661 KLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYA 720 Query: 721 DFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEM 780 DFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEM Sbjct: 721 DFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEM 780 Query: 781 RDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKI 840 RDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKI Sbjct: 781 RDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKI 840 Query: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE Sbjct: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 Query: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD 960 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD Sbjct: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD 960 Query: 961 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK Sbjct: 961 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020 Query: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080 Query: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 Query: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ Sbjct: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 Query: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 Query: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 Query: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 Query: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE Sbjct: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 Query: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES Sbjct: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560 Query: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK 1620 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK 1620 Query: 1621 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER 1680 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER Sbjct: 1621 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER 1680 Query: 1681 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ 1740 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ Sbjct: 1681 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ 1740 Query: 1741 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR Sbjct: 1741 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800 Query: 1801 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE 1860 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE Sbjct: 1801 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE 1860 Query: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ Sbjct: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920 Query: 1921 VNKLRAKSRDVGSQKMEE 1938 VNKLRAKSRDVGSQKMEE Sbjct: 1921 VNKLRAKSRDVGSQKMEE 1938 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 3159 bits (8189), Expect = 0.0 Identities = 1588/1939 (81%), Positives = 1766/1939 (91%), Gaps = 2/1939 (0%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSD+EMAIFGEAAP+LRK E+ERIEAQN+PFD+K + FV D KE +VK +Q+RE KV Sbjct: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 KT +T+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVY EVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKE-TQPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239 SGAGKTVNTKRVIQYFATIAVTG+KKKE GKMQGTLEDQII ANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299 NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQIMSNKKP+L Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300 Query: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359 I++LLI+TNP+D+ FVSQGE+TV SIDD EEL+ATD+AI+ILGF+S+E+V IYKLTGAVM Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360 Query: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419 HYGNMKFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ V Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479 QQV N+VGALAKAVY+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599 CMFPKATDTSFKNKLY+QHLGKSNNFQKPKPAKGK EAHFSL+HYAGTVDYNIAGWLDKN Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600 Query: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENL 659 KDPLNETVVGLYQKS++K L+ LF GAE ++GG KKGGKKKGSSFQTVSA+FRENL Sbjct: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEA-EAGGGKKGGKKKGSSFQTVSALFRENL 659 Query: 660 NKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILY 719 NKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY Sbjct: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719 Query: 720 ADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEE 779 ADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLEE Sbjct: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEE 779 Query: 780 MRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFK 839 MRDEKL L+T TQA+CRG+L RVE++KM+ERR+SIFCIQYN+R+FMNVKHWPWM L+FK Sbjct: 780 MRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFK 839 Query: 840 IKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSET 899 IKPLLKSAE EKEMA MKE+FE+TKEELA++EA+RKELEEKMV+L+QEKNDLQLQVQ+E Sbjct: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899 Query: 900 ENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959 ++L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DID Sbjct: 900 DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959 Query: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019 DLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ EED Sbjct: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019 Query: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079 KVN L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QES MD+ENDKQQ Sbjct: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQ 1079 Query: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139 ++EKLKKKEFE+S LQ+KI+DEQ +Q QKKIKELQARIEELEEEIEAE RAK EKQ Sbjct: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139 Query: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199 RSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199 Query: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259 ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CR +EDQ Sbjct: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 1259 Query: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEEL 1319 SEIK K+E+Q +LI+DL Q+ARLQT++GE S +++EK++L+SQL++ KQA TQQ+EEL Sbjct: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319 Query: 1320 KRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY 1379 KRQ+EEE KAK+A+AHALQSSRHDCDLLREQYEEEQEAKAELQRA+SKANSEVAQWRTKY Sbjct: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379 Query: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439 ETDAIQRTEELEEAKKKLAQRLQ+AEE+ E N+KCASLEKTKQRLQ EVEDLM D+ER+ Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT 1439 Query: 1440 HTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQL 1499 + ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKESRSLSTELFK++NAYEE +DQL Sbjct: 1440 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQL 1499 Query: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559 ETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEKS+LQ ALEE E SLEHEE Sbjct: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEE 1559 Query: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619 KILR+QLEL+QVKSE+DRK+ EKDEEI+Q+KRN R E++QS LDAEIRSRNDA+RLK Sbjct: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619 Query: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679 KKMEGDLNEMEIQL H+NR AE ++ R Q LKD+QLHLDDALRS EDLKEQLA+VE Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679 Query: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739 RR LL E+EE++ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI+ Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739 Query: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799 Q Q E+E+ IQE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH Sbjct: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799 Query: 1800 RLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAE 1859 RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR EA+KG K+ERKVKE+TYQ E Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859 Query: 1860 EDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAES 1919 ED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+N LS+ RR+QHELEEA ERADIAES Sbjct: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919 Query: 1920 QVNKLRAKSRDVGSQKMEE 1938 QVNKLR KSR+V ++ + E Sbjct: 1920 QVNKLRVKSREVHTKIISE 1938 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 3146 bits (8157), Expect = 0.0 Identities = 1583/1940 (81%), Positives = 1766/1940 (91%), Gaps = 2/1940 (0%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSD+E+A+FGEAAP+LRK E+ERIEAQNRPFD+K + FVA+ KE +VKG IQ+RE KV Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 VKT LT+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKET-QPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239 SGAGKTVNTKRVIQYFATIAVTG+KKKE GK+QGTLEDQII ANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299 NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQL +ERSYHIFYQI SNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 Query: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359 I++LLI+TNP+D+PFVSQGE++VASIDD EEL+ATD+AIDILGF++EEKV IYKLTGAVM Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 Query: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419 HYGN+KFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ V Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479 +QV+N+VGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599 CMFPKATDTSFKNKLYDQHLGKS NFQKPK KGKAEAHF+L+HYAG VDYNI GWL+KN Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 Query: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAE-TGDSGGSKKGGKKKGSSFQTVSAVFREN 658 KDPLNETVVGLYQKS++K L+ LFS AE G GG+KKGGKKKGSSFQTVSA+FREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 Query: 659 LNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRIL 718 LNKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRIL Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 Query: 719 YADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLE 778 YADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLE Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Query: 779 EMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFF 838 EMRD+KL L+T TQA CRG+L RVE+++M+ERR++IFCIQYNIRSFMNVKHWPWM LFF Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 Query: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898 KIKPLLKSAE EKEMATMKE+F++ K+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQ+E Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 Query: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958 E L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DI Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Query: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018 DDLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ EE Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 Query: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ 1078 DKVN L K KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QESIMD+EN+KQ Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 1079 QIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEK 1138 Q++EKLKKKEFE+S LQ+KI+DEQ +Q QKKIKELQARIEELEEEIEAE RAK EK Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 Query: 1139 QRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198 QRSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 Query: 1199 KQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVED 1258 K ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CRT+ED Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 Query: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE 1318 Q SE+K+K+E+Q +LI+DL Q+ RLQT++GE S +++EKE+L+SQL++ KQA TQQ+EE Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Query: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTK 1378 LKRQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE+KAELQRALSKAN+EVAQWRTK Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 Query: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438 YETDAIQRTEELEEAKKKLAQRLQ AEE+ E N+KCASLEKTKQRLQ EVEDLM D+ER Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1439 SHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ 1498 ++ ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKE+RSL TELFK++NAYEE +DQ Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 Query: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558 LETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK +LQ ALEE E SLEHE Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 Query: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618 E KILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN R E++QS LDAEIRSRNDA+RL Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 Query: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678 KKKMEGDLNEMEIQL H+NR AE ++ R QG LKD+Q+HLDDALRS EDLKEQLA+V Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 Query: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADI 1738 ERR LL E+EE++ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 1739 AQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798 +Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 Query: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858 RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG K+ER+VKE+TYQ Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 Query: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918 EED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+NT L++ R++QHELEEA ERADIAE Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 Query: 1919 SQVNKLRAKSRDVGSQKMEE 1938 SQVNKLR KSR+V ++ + E Sbjct: 1921 SQVNKLRVKSREVHTKVISE 1940 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 3146 bits (8157), Expect = 0.0 Identities = 1583/1940 (81%), Positives = 1766/1940 (91%), Gaps = 2/1940 (0%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSD+E+A+FGEAAP+LRK E+ERIEAQNRPFD+K + FVA+ KE +VKG IQ+RE KV Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 VKT LT+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKET-QPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239 SGAGKTVNTKRVIQYFATIAVTG+KKKE GK+QGTLEDQII ANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299 NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQL +ERSYHIFYQI SNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 Query: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359 I++LLI+TNP+D+PFVSQGE++VASIDD EEL+ATD+AIDILGF++EEKV IYKLTGAVM Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 Query: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419 HYGN+KFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ V Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479 +QV+N+VGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599 CMFPKATDTSFKNKLYDQHLGKS NFQKPK KGKAEAHF+L+HYAG VDYNI GWL+KN Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 Query: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAE-TGDSGGSKKGGKKKGSSFQTVSAVFREN 658 KDPLNETVVGLYQKS++K L+ LFS AE G GG+KKGGKKKGSSFQTVSA+FREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 Query: 659 LNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRIL 718 LNKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRIL Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 Query: 719 YADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLE 778 YADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLE Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Query: 779 EMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFF 838 EMRD+KL L+T TQA CRG+L RVE+++M+ERR++IFCIQYNIRSFMNVKHWPWM LFF Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 Query: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898 KIKPLLKSAE EKEMATMKE+F++ K+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQ+E Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 Query: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958 E L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DI Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Query: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018 DDLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ EE Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 Query: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ 1078 DKVN L K KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QESIMD+EN+KQ Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 1079 QIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEK 1138 Q++EKLKKKEFE+S LQ+KI+DEQ +Q QKKIKELQARIEELEEEIEAE RAK EK Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 Query: 1139 QRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198 QRSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 Query: 1199 KQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVED 1258 K ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CRT+ED Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 Query: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE 1318 Q SE+K+K+E+Q +LI+DL Q+ RLQT++GE S +++EKE+L+SQL++ KQA TQQ+EE Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Query: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTK 1378 LKRQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE+KAELQRALSKAN+EVAQWRTK Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 Query: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438 YETDAIQRTEELEEAKKKLAQRLQ AEE+ E N+KCASLEKTKQRLQ EVEDLM D+ER Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1439 SHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ 1498 ++ ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKE+RSL TELFK++NAYEE +DQ Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 Query: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558 LETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK +LQ ALEE E SLEHE Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 Query: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618 E KILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN R E++QS LDAEIRSRNDA+RL Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 Query: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678 KKKMEGDLNEMEIQL H+NR AE ++ R QG LKD+Q+HLDDALRS EDLKEQLA+V Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 Query: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADI 1738 ERR LL E+EE++ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 1739 AQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798 +Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 Query: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858 RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG K+ER+VKE+TYQ Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 Query: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918 EED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+NT L++ R++QHELEEA ERADIAE Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 Query: 1919 SQVNKLRAKSRDVGSQKMEE 1938 SQVNKLR KSR+V ++ + E Sbjct: 1921 SQVNKLRVKSREVHTKVISE 1940 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 3141 bits (8143), Expect = 0.0 Identities = 1577/1939 (81%), Positives = 1763/1939 (90%), Gaps = 2/1939 (0%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSD+EMAIFGEAAP+LRK EKERIEAQN+PFD+K + FV D KE YVK ++Q+RE KV Sbjct: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 KT +T+ DQVF MNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVY PEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQP-GKMQGTLEDQIIQANPLLEAFGNAKTVR 239 SGAGKTVNTKRVIQYFATIAVTG+KKKE GKMQGTLEDQII ANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI+SNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300 Query: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359 I++LLI+TNP+DF FVSQGE+TV SIDD EEL+ATD+A+DILGF+++EKV IYKLTGAVM Sbjct: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360 Query: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419 HYGNMKFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNE+VTKGQ V Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420 Query: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479 QQV N+VGALAKA+YEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599 CMFPKATDTSFKNKLY+QHLGKSNNFQKPKPAKGK EAHFSLVHYAGTVDYNIAGWLDKN Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600 Query: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENL 659 KDPLNETVVGLYQKS++K L+FLFS AE + GG KKGGKKKGSSFQTVSA+FRENL Sbjct: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEA-EGGGGKKGGKKKGSSFQTVSALFRENL 659 Query: 660 NKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILY 719 NKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY Sbjct: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719 Query: 720 ADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEE 779 ADFKQRY++LNASAIPEGQFIDSK ASEKLL SI++D Q++FG+TKVFFKAGLLG LEE Sbjct: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEE 779 Query: 780 MRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFK 839 MRDEKL L+T TQA+CRG+LMRVEF+KMMERR+SIFCIQYNIR+FMNVKHWPWM L+FK Sbjct: 780 MRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFK 839 Query: 840 IKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSET 899 IKPLLKSAE EKEMA MKE+FE+TKEELA++EA+RKELEEKMV+L+QEKNDLQLQVQ+E Sbjct: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899 Query: 900 ENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959 + L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DID Sbjct: 900 DALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959 Query: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019 DLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ+EED Sbjct: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED 1019 Query: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079 KVN L K KLEQQ DDLEGSLEQEKKL DLERAKRKLEGDLK++QES MD ENDKQQ Sbjct: 1020 KVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQ 1079 Query: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139 + EKLKKKEFE+S LQ KI+DEQ ++Q QKKIKELQARIEELEEEIEAE RAK EKQ Sbjct: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139 Query: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199 RSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRKK Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKK 1199 Query: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259 ADSVAELGEQID+LQRVKQKLEKEKSELKMEI+D+ASN+E +SK+K+N E+ CRT+EDQ Sbjct: 1200 HADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQ 1259 Query: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEEL 1319 SEIK K+E+Q +LI++L+ QKARL T++GE S +++EK++++SQL++ KQA TQQ+EEL Sbjct: 1260 LSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEEL 1319 Query: 1320 KRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY 1379 KRQ+EEETKAK+ +AHALQS+RHDCDLLREQYEEEQEAKAELQR +SKANSEVAQWRTKY Sbjct: 1320 KRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKY 1379 Query: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439 ETDAIQRTEELEEAKKKLAQRLQ+AEE+ E NSKCASLEKTKQRLQ EVEDLM D+ERS Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERS 1439 Query: 1440 HTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQL 1499 + AC LDKKQRNFDKVLAEWKQK +E+QAELEA+QKESRSLSTELFK++NAYEE +D L Sbjct: 1440 NAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHL 1499 Query: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559 ETL+RENKNLQ+EISDLTEQIAE GK++ E EK KK ++ EKS+LQ +LEE E SLEHEE Sbjct: 1500 ETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEE 1559 Query: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619 KILR+QLEL+QVKSE+DRK+ EKDEE++QLKRN R E++QS LDAEIRSRNDALR+K Sbjct: 1560 GKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIK 1619 Query: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679 KKMEGDLNEMEIQL H+NRQ AE ++LR QG LKD+QLHLDDA+R +DLKEQLA+VE Sbjct: 1620 KKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVE 1679 Query: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739 RR L+ E+EE++ +LE+TER R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI+ Sbjct: 1680 RRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739 Query: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799 Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1740 QIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1799 Query: 1800 RLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAE 1859 RLDEAEQLALKGGKKQIQKLE RVRELE+E++ EQK EA+KG K+ER+VKE+TYQ E Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTE 1859 Query: 1860 EDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAES 1919 ED KNILRLQDLVDKLQ KVK+YKRQAEEAEEQ+N L++ R++QHELEEA ERADIAES Sbjct: 1860 EDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAES 1919 Query: 1920 QVNKLRAKSRDVGSQKMEE 1938 QVNKLR KSR+V ++ + E Sbjct: 1920 QVNKLRVKSREVHTKVISE 1938 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 3138 bits (8137), Expect = 0.0 Identities = 1582/1930 (81%), Positives = 1752/1930 (90%), Gaps = 3/1930 (0%) Query: 2 SSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVI 61 SSDAEMA+FGEAAPYLRK EKERIEAQN+PFD+K + FVA+ KE YVK IQ++E KV Sbjct: 4 SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63 Query: 62 VKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121 VKT LT+ DQVFPMNPPK+DKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL Sbjct: 64 VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123 Query: 122 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGES 181 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGES Sbjct: 124 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183 Query: 182 GAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRND 241 GAGKTVNTKRVIQYFATIAVTG+KKK+ + GKMQGTLEDQII ANPLLEAFGNAKTVRND Sbjct: 184 GAGKTVNTKRVIQYFATIAVTGEKKKD-ESGKMQGTLEDQIISANPLLEAFGNAKTVRND 242 Query: 242 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELID 301 NSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI SNKKP+LI+ Sbjct: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIE 302 Query: 302 LLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHY 361 +LLI+TNP+D+ FVSQGE+TV SIDD EEL+ATD+AIDILGF+ EEKV IYKLTGAVMHY Sbjct: 303 MLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHY 362 Query: 362 GNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQ 421 GNMKFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ VQQ Sbjct: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422 Query: 422 VTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 481 V N+VGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN Sbjct: 423 VYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482 Query: 482 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 541 FTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKP+GIFSILEEECM Sbjct: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECM 542 Query: 542 FPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKD 601 FPKATDTSFKNKLYDQHLGKS NFQKPK KGKAEAHFSL+HYAGTVDYNI GWLDKNKD Sbjct: 543 FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKD 602 Query: 602 PLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNK 661 PLN+TVVGLYQKS++K L+ LFS YA AE S +KKG KKKGSSFQTVSA+FRENLNK Sbjct: 603 PLNDTVVGLYQKSAMKTLASLFSTYASAEADSS--AKKGAKKKGSSFQTVSALFRENLNK 660 Query: 662 LMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYAD 721 LMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY D Sbjct: 661 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720 Query: 722 FKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMR 781 FKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLEEMR Sbjct: 721 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780 Query: 782 DEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIK 841 DEKL ++T TQAVCRG+LMRVE++KM++RR+++FCIQYN+R+FMNVKHWPWM LFFKIK Sbjct: 781 DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840 Query: 842 PLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETEN 901 PLLKSAE EKEMATMKE+F++TK+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQSE ++ Sbjct: 841 PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900 Query: 902 LMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDL 961 L DAEERCE LIK+KI LEAK+KE+TER EEEEE+N+EL AKKR LED+CS LK+DIDDL Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960 Query: 962 ELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKV 1021 ELTL KVEKEKHATENKVKNL+EEM L+E I+KL+KEKK+LQE HQQTLDDLQ EEDKV Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020 Query: 1022 NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIE 1081 N L K KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QES MD+ENDKQQ++ Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080 Query: 1082 EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141 EKL+KKEFE+S L +KI+DEQ +Q QKKIKELQARIEEL EEIEAE RAK EKQRS Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140 Query: 1142 DLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQA 1201 DL+RELEEISERLEEA GATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA A LRKK A Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200 Query: 1202 DSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFS 1261 DS+AELGEQIDNLQRVKQKLEKEKSELKME DD++SN EA+SK+K N+E+ CR++EDQ S Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260 Query: 1262 EIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKR 1321 E+K K+E+Q +LI+DL Q+ARLQT+ GE S +++EK++L+SQL++SKQA TQQ+EELK Sbjct: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320 Query: 1322 QMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET 1381 Q+EEETKAKNA+AHALQSSRHDCDLLREQYEEEQE KAELQRALSKANSEVAQWRTKYET Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380 Query: 1382 DAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHT 1441 DAIQRTEELEEAKKKLAQRLQEAEE+ E N+KCASLEKTKQRLQ EVEDLM D+ERS+ Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440 Query: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLET 1501 ACA LDKKQRNFDKVL+EWKQK +E+QAELEA+QKESRSLSTELFK++N YEE +DQLET Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500 Query: 1502 LRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561 LRRENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK ++Q ALEE E SLEHEE K Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560 Query: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621 ILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN R E +QS LDAEIRSRNDALR+KKK Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620 Query: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681 MEGDLNEMEIQL H+NR AE+ ++ R QG LK++QLHLDDALR EDLKEQLAIVERR Sbjct: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680 Query: 1682 NGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQC 1741 LL E+EE+ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE D++Q Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740 Query: 1742 QAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801 Q+EVE IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800 Query: 1802 DEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEED 1861 DEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG K+ER+VKE+TYQ EED Sbjct: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860 Query: 1862 HKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921 KN+LRLQDLVDKLQAKVKSYKRQAEEAEEQ+N LS+ R++QHELEEA ERADIAESQV Sbjct: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920 Query: 1922 NKLRAKSRDV 1931 NKLR KSR+V Sbjct: 1921 NKLRVKSREV 1930 Score = 171 bits (434), Expect = 5e-42 Identities = 179/861 (20%), Positives = 372/861 (43%), Gaps = 136/861 (15%) Query: 838 FKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQ---EKNDLQLQ 894 F+I L+ E E+ + + ++ KE AR E +E+E + S + +++DL + Sbjct: 1088 FEISNLISKIEDEQAVEIQLQ--KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRE 1145 Query: 895 VQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLE-DKCSS 953 ++ +E L +A ++ EA+ ++L LEE + +VA R D + Sbjct: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205 Query: 954 LKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEE---NISKLTK-------EKKSL 1003 L ID+L+ K+EKEK + + +LS A+ + N+ K+ + E K+ Sbjct: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265 Query: 1004 QEAHQQTLDDLQVEEDK------------------VNGLIKINAKLEQQTDDLEGSLEQE 1045 +E Q+ ++DL + + V+ L + QQ ++L+ LE+E Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325 Query: 1046 KKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHS 1105 K + L A + D + +E + + K +++ L K E++Q + K + + + Sbjct: 1326 TKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1385 Query: 1106 LQ-FQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQ 1164 + ++ K+L R++E EE +EA + A +EK + L E+E++ +E ++ A +A Sbjct: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAAL 1445 Query: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRK------KQADSVAELGEQIDNLQRVK 1218 + + + + ++ EE + EA+ R K + E +Q++ L+R Sbjct: 1446 DKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN 1505 Query: 1219 QKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLN 1278 + L++E S+L +I + I L K K +E+ ++ E +A E + I + Sbjct: 1506 KNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQ 1565 Query: 1279 MQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE--------------LKRQME 1324 ++ L E+ ++ EK+ I QL ++ + + ++ +K++ME Sbjct: 1566 LE---LNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKME 1622 Query: 1325 EETK--------AKNAMAHALQSSRHDCDLLREQY----------EEEQEAKAELQRALS 1366 + A A +L++ R+ +L+E E+ +E A ++R + Sbjct: 1623 GDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1682 Query: 1367 KANSEVAQ-WRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRL 1425 +E+ + W T E+ E ++K Q L +A E + +++ SL TK++L Sbjct: 1683 LLQAEIEELWAT---------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1733 Query: 1426 -------QGEVEDLMRD---------------------LERSHTACATLDKKQRNFDKVL 1457 Q EVE+++++ L++ A L++ ++N ++ + Sbjct: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1793 Query: 1458 AEWKQKLDESQ----------------------AELEAAQKESRSLSTELFKMRNAYEEV 1495 + + +LDE++ E+E QK + L K +E+ Sbjct: 1794 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL 1853 Query: 1496 VDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL 1555 Q E R+ LQ+ + L ++ + +EAE+ + LQ LEE E Sbjct: 1854 TYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERA 1913 Query: 1556 EHEESKILRVQLELSQVKSEL 1576 + ES++ +++++ +V +++ Sbjct: 1914 DIAESQVNKLRVKSREVHTKI 1934 Score = 69.3 bits (168), Expect = 3e-11 Identities = 68/315 (21%), Positives = 147/315 (46%), Gaps = 30/315 (9%) Query: 846 SAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDA 905 +AE+ + + + T+ L + +++L+E++ + + N LQ +++ L Sbjct: 1639 AAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698 Query: 906 EERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTL 965 E +S+ + E ++ + +ER++ N+ L+ K+ LE+ S L+ +++++ Sbjct: 1699 E-------RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQES 1751 Query: 966 TKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLI 1025 E++ ++EE+ ++ + L + KK+L+ QT+ DLQ D+ L Sbjct: 1752 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQLA 1807 Query: 1026 -----KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKM-------SQESIMDL 1073 K KLE + +LEG +E E+K A+ + RK E +K +++++ L Sbjct: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRL 1867 Query: 1074 EN--DKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHT 1131 ++ DK Q + K K++ E ++ Q+ + + LQ EL+ E + + Sbjct: 1868 QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQ-----HELEEAEERADIAESQVNK 1922 Query: 1132 LRAKIEKQRSDLARE 1146 LR K + + ++ E Sbjct: 1923 LRVKSREVHTKISAE 1937 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 3070 bits (7960), Expect = 0.0 Identities = 1530/1936 (79%), Positives = 1748/1936 (90%), Gaps = 3/1936 (0%) Query: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 MSSD EM +FG AAP+LRK EKERIEAQN+PFD+K CFV D+KE Y KG I++ ++ KV Sbjct: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60 Query: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 V+T D+R L + + V+ MNPPKFD+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG Sbjct: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 LFCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRN 240 SGAGKTVNTKRVIQYFATIA TGD K+ + KM+GTLEDQII ANPLLEAFGNAKTVRN Sbjct: 181 SGAGKTVNTKRVIQYFATIAATGDLAKK-KDSKMKGTLEDQIISANPLLEAFGNAKTVRN 239 Query: 241 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELI 300 DNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI+SNKKPELI Sbjct: 240 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELI 299 Query: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360 +LLLI+TNP+D+PF+SQGE+ VASIDD+EELLATD+AIDILGF+ EEK G+YKLTGAVMH Sbjct: 300 ELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMH 359 Query: 361 YGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQ 420 YGNMKFKQKQREEQAEPDGTEVADK YLMGLNS+++LK LC PRVKVGNEYVTKGQ V Sbjct: 360 YGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVD 419 Query: 421 QVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 480 QV ++V AL+K+VYEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLCI Sbjct: 420 QVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCI 479 Query: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 540 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEEC Sbjct: 480 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 539 Query: 541 MFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNK 600 MFPKATDTSFKNKLYDQHLGKSNNFQKPK KG+AEAHFSL+HYAGTVDY+++GWL+KNK Sbjct: 540 MFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNK 599 Query: 601 DPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLN 660 DPLNETVVGLYQKSS +LL+ L++ +A A+ G KK KKKGSSFQTVSA+FRENLN Sbjct: 600 DPLNETVVGLYQKSSNRLLAHLYATFATADA--DSGKKKVAKKKGSSFQTVSALFRENLN 657 Query: 661 KLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYA 720 KLM+NLR+THPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFP+RILY Sbjct: 658 KLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYG 717 Query: 721 DFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEM 780 DFKQRYR+LNASAIPEGQFIDSK A EKLL SID+D Q++FG+TKVFFKAGLLG LEEM Sbjct: 718 DFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEM 777 Query: 781 RDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKI 840 RD++L L+T TQAVCRG+LMRVEF+KM++RR+SIFCIQYNIRSFMNVKHWPWM LFFKI Sbjct: 778 RDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKI 837 Query: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 KPLLKSAE EKEMATMKE+F++TK+ELA+SEA+RKELEEK+V+L+QEKNDLQLQVQ+E+E Sbjct: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897 Query: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD 960 NL+DAEERC+ LIK+K LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DIDD Sbjct: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957 Query: 961 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020 LELTL KVEKEKHATENKVKNL+EE++ L+E I+KLT+EKK+LQEAHQQ LDDLQ EEDK Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017 Query: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080 VN L K +KLEQQ +DLE SLEQEKKLR DLER KRKLEGDLK++QESI+DLENDKQQ+ Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077 Query: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 +E+LKKK+FE QLQ+K++DEQ LQFQKKIKELQARIEELEEEIEAE RAK EKQR Sbjct: 1078 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137 Query: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 SD ARELEE+SERLEEA G TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRKK Sbjct: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197 Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 ADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDD++S++E++SKSK+N+E+ CRT+EDQ Sbjct: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257 Query: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 SE + K+E+ + + +L QK+RLQT+ GELS ++EEKES++SQL++SKQA TQQ EELK Sbjct: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317 Query: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 RQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE KAELQRALSKANSEVAQWRTKYE Sbjct: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377 Query: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 TDAIQRTEELEEAKKKLAQRLQ++EE E N+KCASLEKTKQRLQGEVEDLM D+ER++ Sbjct: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437 Query: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 + A LDKKQRNFDKVLAEWK K +ESQAELEA+ KESRSLSTELFK++NAYEE +DQLE Sbjct: 1438 SLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLE 1497 Query: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560 T++RENKNL++EI+DLTEQIAE GK + E EK++K +E EK+D+Q+ALEE E +LEHEE+ Sbjct: 1498 TVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEA 1557 Query: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK 1620 KILR+QLEL+QVKSE+DRK+ EKDEEIEQLKRN QR E +QS LDAE+RSRN+A+RLKK Sbjct: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 1617 Query: 1621 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER 1680 KMEGDLNE+EIQL H+NRQ AET KHLR+VQGQLKD+QLHLDDALR EDLKEQLAIVER Sbjct: 1618 KMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVER 1677 Query: 1681 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ 1740 R LL E+EE++ LEQTER R+L+EQELLD+++RVQLLH+QNTSLI+TKKKLE D+ Q Sbjct: 1678 RANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ 1737 Query: 1741 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800 Q+EVE++ +++RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR Sbjct: 1738 LQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1797 Query: 1801 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE 1860 LDEAEQLALKGGKKQIQKLE R+RELE EL+ EQK+ E++KG KYER+VKE+TYQ+EE Sbjct: 1798 LDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857 Query: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920 D KN+LRLQDLVDKLQ KVKSYKRQAEEA+EQAN L++ R+ QHELEEA ERADIAESQ Sbjct: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917 Query: 1921 VNKLRAKSRDVGSQKM 1936 VNKLRAK+RD S +M Sbjct: 1918 VNKLRAKTRDFTSSRM 1933 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 2992 bits (7757), Expect = 0.0 Identities = 1501/1937 (77%), Positives = 1715/1937 (88%), Gaps = 2/1937 (0%) Query: 3 SDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIV 62 +DA+MA FG AA YLRK EKER+EAQ RPFD + CFV D+KE +VK I +RE KVI Sbjct: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61 Query: 63 KTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122 +T + + +T+ DQV NPPKFDKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF Sbjct: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121 Query: 123 CVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESG 182 CVTVNPYKWLPVY EVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDR+NQSILITGESG Sbjct: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181 Query: 183 AGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDN 242 AGKTVNTKRVIQYFA+IA GD+ K+ +GTLEDQIIQANP LEAFGNAKTVRNDN Sbjct: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241 Query: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDL 302 SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQL +ER+YHIFYQI+SNKKPEL+D+ Sbjct: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301 Query: 303 LLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362 LL++ NP+D+ FVSQGEV+VASIDDSEEL+ATD+A D+LGF+SEEK G+YKLTGA+MHYG Sbjct: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361 Query: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422 NMKFKQKQREEQAEPDGTE ADK+ YLMGLNSA++LKGLC PRVKVGNEYVTKGQ+VQQV Sbjct: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421 Query: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 482 S+GALAKAVYEKMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF Sbjct: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481 Query: 483 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 542 TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF Sbjct: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541 Query: 543 PKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDP 602 PKATD +FK KLYD HLGKSNNFQKP+ KGK EAHFSL+HYAGTVDYNI GWL+KNKDP Sbjct: 542 PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601 Query: 603 LNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKL 662 LNETVV LYQKSSLKL++ LFS+YA A+TGDSG SK GGKKKGSSFQTVSA+ RENLNKL Sbjct: 602 LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSK-GGKKKGSSFQTVSALHRENLNKL 660 Query: 663 MTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADF 722 MTNLR+THPHFVRC+IPNE K PGVMD+ LVMHQLRCNGVLEGIRICRKGFP+RILY DF Sbjct: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720 Query: 723 KQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRD 782 +QRYRILN AIPEGQFIDS+ +EKLL+S+D+D Q++FG+TKVFFKAGLLGLLEEMRD Sbjct: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780 Query: 783 EKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKP 842 E+L ++T QA RG LMR+EFKK++ERRD++ IQ+NIR+FM VK+WPWM L+FKIKP Sbjct: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840 Query: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902 LLKSAE EKEMATMKE+F R KE L +SEARRKELEEKMVSLLQEKNDLQLQVQ+E +NL Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900 Query: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962 DAEERC+ LIK+KI LEAKVKE+ ERLE+EEEMN+EL AKKR LED+CS LK+DIDDLE Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960 Query: 963 LTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN 1022 LTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQ LDDLQVEEDKVN Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020 Query: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEE 1082 L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QESIMDLENDK Q+EE Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080 Query: 1083 KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142 KLKKKEF+++Q +KI+DEQV +LQ QKK+KE QARIEELEEE+EAE T RAK+EK RSD Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140 Query: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202 L+RELEEISERLEEA GATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKK AD Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200 Query: 1203 SVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSE 1262 SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + K+K+N+E+ RT+EDQ +E Sbjct: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260 Query: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQ 1322 + K E+ + ++D Q+A+LQT+NGEL+ ++EEKE+LISQLT+ K + TQQ+E+LKRQ Sbjct: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320 Query: 1323 MEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382 +EEE KAKNA+AHALQS+RHDCDLLREQYEEE EAKAELQR LSKANSEVAQWRTKYETD Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380 Query: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442 AIQRTEELEEAKKKLAQRLQ+AEE E N+KC+SLEKTK RLQ E+EDLM D+ERS+ A Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440 Query: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL 1502 A LDKKQRNFDK+LAEWKQK +ESQ+ELE++QKE+RSLSTELFK++NAYEE ++ LET Sbjct: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500 Query: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562 +RENKNLQEEISDLTEQ+ E GKN+ E EK +K +E EK +LQ ALEE E SLEHEE KI Sbjct: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560 Query: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622 LR QLE +Q+K+E++RK+ EKDEE+EQ KRN QR ++LQ+ LDAE RSRN+ LR+KKKM Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620 Query: 1623 EGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN 1682 EGDLNEMEIQL H+NR AE QK ++++Q LKD+Q+ LDDA+R+N+DLKE +AIVERRN Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680 Query: 1683 GLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ 1742 LL ELEE++ +EQTER+R+L+EQEL++ S+RVQLLHSQNTSLIN KKK+E+D+ Q Q Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740 Query: 1743 AEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802 +EVE ++QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800 Query: 1803 EAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDH 1862 EAEQ+ALKGGKKQ+QKLE RVRELE EL+ EQKR AE++KG K ER++KE+TYQ EED Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860 Query: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVN 1922 KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQANT LS+ R+VQHEL+EA ERADIAESQVN Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920 Query: 1923 KLRAKSRDVGS-QKMEE 1938 KLRAKSRD+G+ QKM + Sbjct: 1921 KLRAKSRDIGAKQKMHD 1937 Score = 78.2 bits (191), Expect = 7e-14 Identities = 92/408 (22%), Positives = 181/408 (44%), Gaps = 69/408 (16%) Query: 757 REQFRFGNTKVFFKAGLLGLLEEMRDEK------LVTLMTSTQAVCRGYLMRVEFKKMME 810 R Q F K + L EEM K + +L TS A R + KK ME Sbjct: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621 Query: 811 RRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARS 870 + IQ + + M +AEA+K++ +++ + T+ +L + Sbjct: 1622 GDLNEMEIQLSHANRM-------------------AAEAQKQVKSLQSLLKDTQIQLDDA 1662 Query: 871 EARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERL 930 +L+E +++++ +N+L +Q+E E L E+ E +S+ L E ++ E +ER+ Sbjct: 1663 VRANDDLKEN-IAIVERRNNL---LQAELEELRAVVEQTE---RSRKLAEQELIETSERV 1715 Query: 931 EEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALE 990 + N+ L+ +K+ +E + L+ ++++ E++ ++EE+ + Sbjct: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1775 Query: 991 ENISKLTKEKKSLQEAHQQTLDDLQ-----VEEDKVNGLIKINAKLEQQTDDLEGSLEQE 1045 + + L + KK+++ QT+ DLQ E+ + G K KLE + +LEG LE E Sbjct: 1776 DTSAHLERMKKNME----QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAE 1831 Query: 1046 KKLRADLERAKRKLEGDLK-MSQESIMDLEN-----------------DKQQIEE----- 1082 +K A+ + RK E +K ++ ++ D +N K+Q EE Sbjct: 1832 QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQA 1891 Query: 1083 -----KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEE 1125 K +K + EL + + + D + + + K +++ A+ + +EE Sbjct: 1892 NTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 2977 bits (7717), Expect = 0.0 Identities = 1494/1936 (77%), Positives = 1704/1936 (88%), Gaps = 5/1936 (0%) Query: 4 DAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVK 63 D+EMA+FG AAPYLRK EKER+EAQ RPFD KK FV D+K+ +VK I +RE KV + Sbjct: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62 Query: 64 TLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123 T + +T+ DQV NPPKFDKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC Sbjct: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122 Query: 124 VTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGA 183 VTVNPYKWLPVY PEVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDR+NQSILITGESGA Sbjct: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182 Query: 184 GKTVNTKRVIQYFATIAVTGDK-KKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDN 242 GKTVNTKRVIQYFA IA GD+ KK+ PGK GTLEDQIIQANP LEAFGNAKTVRNDN Sbjct: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240 Query: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDL 302 SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQL +ER YHIFYQI+SNKKPEL+D+ Sbjct: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300 Query: 303 LLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362 LLI+ NP+D+ F+SQGE TVASIDD+EEL+ATDNA D+LGF+SEEK +YKLTGA+MH+G Sbjct: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360 Query: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422 NMKFK KQREEQAEPDGTE ADK+ YLMGLNSA++LKGLC PRVKVGNEYVTKGQNVQQV Sbjct: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420 Query: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 482 + GALAKAVYE+MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF Sbjct: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480 Query: 483 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 542 TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF Sbjct: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540 Query: 543 PKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDP 602 PKATD +FK KL+D HLGKS NFQKP+ KGK EAHFSL+HYAG VDYNI GWL KNKDP Sbjct: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600 Query: 603 LNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKL 662 LNETVVGLYQKSSLKLLS LF+NYAGA+ G KG KKGSSFQTVSA+ RENLNKL Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG--KGKAKKGSSFQTVSALHRENLNKL 658 Query: 663 MTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADF 722 MTNLRSTHPHFVRC+IPNETK+PGVMD+ LVMHQLRCNGVLEGIRICRKGFP+RILY DF Sbjct: 659 MTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 718 Query: 723 KQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRD 782 +QRYRILN +AIPEGQFIDS+ +EKLL+S+D+D Q++FG+TKVFFKAGLLGLLEEMRD Sbjct: 719 RQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 778 Query: 783 EKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKP 842 E+L ++T QA RG L R+E+KK++ERRDS+ IQ+NIR+FM VK+WPWM L+FKIKP Sbjct: 779 ERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP 838 Query: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902 LLKSAE EKEMA+MKE+F R KE L +SEARRKELEEKMVSLLQEKNDLQLQVQ+E +NL Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898 Query: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962 DAEERC+ LIK+KI LEAKVKE+ ERLE+EEEMN+EL AKKR LED+CS LKRDIDDLE Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958 Query: 963 LTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN 1022 LTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQ LDDLQ EEDKVN Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018 Query: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEE 1082 L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QESIMDLENDKQQ++E Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078 Query: 1083 KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142 +LKKK+FEL+ L A+I+DEQ Q QKK+KELQARIEELEEE+EAE T RAK+EK RSD Sbjct: 1079 RLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD 1138 Query: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202 L+RELEEISERLEEA GATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKK AD Sbjct: 1139 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1198 Query: 1203 SVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSE 1262 SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + K+K+N+E+ CRT+EDQ +E Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258 Query: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQ 1322 ++K E+ + ++DL Q+A+LQT+NGELS +++EKE+LISQLT+ K TQQLE+LKRQ Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQ 1318 Query: 1323 MEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382 +EEE KAKNA+AHALQS+RHDCDLLREQYEEE EAKAELQR LSKANSEVAQWRTKYETD Sbjct: 1319 LEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378 Query: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442 AIQRTEELEEAKKKLAQRLQEAEE E N+KC+SLEKTK RLQ E+EDLM D+ERS+ A Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1438 Query: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL 1502 A LDKKQRNFDK+LAEWKQK +ESQ+ELE++QKE+RSLSTELFK++NAYEE ++ LET Sbjct: 1439 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1498 Query: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562 +RENKNLQEEISDLTEQ+ +GK + E EK +K +E EK +LQ ALEE E SLEHEE KI Sbjct: 1499 KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKI 1558 Query: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622 LR QLE +Q+K+E++RK+ EKDEE+EQ KRN R ++LQ+ LDAE RSRN+ALR+KKKM Sbjct: 1559 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM 1618 Query: 1623 EGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN 1682 EGDLNEMEIQL H+NR AE QK ++++Q LKD+Q+ LDDA+R+N+DLKE +AIVERRN Sbjct: 1619 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1678 Query: 1683 GLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ 1742 LL ELEE++ +EQTER+R+L+EQEL++ S+RVQLLHSQNTSLIN KKK++AD++Q Q Sbjct: 1679 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ 1738 Query: 1743 AEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802 EVE ++QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD Sbjct: 1739 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798 Query: 1803 EAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDH 1862 EAEQ+ALKGGKKQ+QKLE RVRELENEL+ EQKR AE++KG K ER++KE+TYQ EED Sbjct: 1799 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 1858 Query: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVN 1922 KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQANT LS+ R+VQHEL+EA ERADIAESQVN Sbjct: 1859 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1918 Query: 1923 KLRAKSRDVGSQKMEE 1938 KLRAKSRD+G++ + E Sbjct: 1919 KLRAKSRDIGTKGLNE 1934 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 2544 bits (6594), Expect = 0.0 Identities = 1273/1941 (65%), Positives = 1598/1941 (82%), Gaps = 10/1941 (0%) Query: 6 EMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTREND-KVIVKT 64 +++ GE+A YLR+ +E + P+D KK +V D ++ YV+ +++ +V V+T Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104 Query: 65 LDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124 D ++L + ++ PMNPP+FD +EDMAMMTHL+E +VL+NL++RYA WMIYTYSGLFCV Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164 Query: 125 TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAG 184 T+NPYKWLPVY VVAAY+GK+R ++PPHI++++DNAY ML +RDNQS+LITGESGAG Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224 Query: 185 KTVNTKRVIQYFATIAVTGD---KKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRND 241 KTVNTKRVIQYFA +A GD KK + K GTLEDQII+ANP +EAFGNAKT+RND Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284 Query: 242 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELID 301 NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV FQL ERSYH++YQI+S +KPEL D Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344 Query: 302 LLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHY 361 +LL+S NP+D+ F SQG +TV +++D EEL+ATD+A+DILGFS +EK YK+ GA++H+ Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404 Query: 362 GNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQ 421 GNMKFKQKQREEQAE DGTE ADKA YLMG++S ++LKGL PRV+VGNEYVTKGQ+V+Q Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464 Query: 422 VTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 481 V +VGALAKA Y+++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS EQLCIN Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524 Query: 482 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 541 FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL CI+LIEKP+GI SILEEECM Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584 Query: 542 FPKATDTSFKNKLYDQHLGKSNNFQKPKP-AKGKAEAHFSLVHYAGTVDYNIAGWLDKNK 600 FPKA+D SF+ KLYD H GKS NFQ+P+P K K +AHF +VHYAG V Y+I GWL+KNK Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644 Query: 601 DPLNETVVGLYQKSSLKLLSFLFSNYAGA---ETGDSGGSKKGGKKKGSSFQTVSAVFRE 657 DPLNETVV ++QKS +LL+ L+ NYAG+ E SG +K +KK +SFQTVS + +E Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEK--RKKAASFQTVSQLHKE 702 Query: 658 NLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRI 717 NLNKLMTNLR+T PHFVRC++PNE KTPGVMD +LV+HQLRCNGVLEGIRICR+GFP+R+ Sbjct: 703 NLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRL 762 Query: 718 LYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLL 777 LY DF+QRYRILN SAIP+ F+DS+ A+EKLL S+D+D Q++FG+TKVFFKAGLLG+L Sbjct: 763 LYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVL 822 Query: 778 EEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLF 837 EE+RD++L ++T QA RG LMR+E+++++ RD++F IQ+NIR+F VK+W WM LF Sbjct: 823 EELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLF 882 Query: 838 FKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQS 897 FK+KPLL+SA+AE+E+A ++ + + LA +EA+R+ELEE VS+ QEKNDL LQ+Q+ Sbjct: 883 FKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQA 942 Query: 898 ETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRD 957 E +NL DAEERC LIKSK+ LE KVKEL+ERLE+EEE+N++L A++R LED+C+ LK+D Sbjct: 943 EQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKD 1002 Query: 958 IDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE 1017 IDDL+LTL K EKEK ATENKVKNL+EEM AL+E++++LTKEKK+LQEAHQQ L DLQ E Sbjct: 1003 IDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAE 1062 Query: 1018 EDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDK 1077 ED+V+ L K +LEQQ +DLE SLEQEKKLR D ERAKRKLEGDLK++QES+ D DK Sbjct: 1063 EDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDK 1122 Query: 1078 QQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIE 1137 QQ+EEKLKKK+ ELSQL +++DEQ+ Q QKKIKELQAR EELEEE+EAE RA++E Sbjct: 1123 QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVE 1182 Query: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1197 KQR++ ARELEE+SERLEEA GA++ Q E +KREAE ++RR+LEEA L+HEAT A LR Sbjct: 1183 KQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALR 1242 Query: 1198 KKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE 1257 +KQA+ AELGEQ+D+LQRV+QKLEKEKSEL+ME+DD+A+N+E L+++K++ E+ CRT E Sbjct: 1243 RKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE 1302 Query: 1258 DQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317 DQ SE K K E+ + + D + Q+ RLQT++GELS +EEKE LISQL++ K Q LE Sbjct: 1303 DQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE 1362 Query: 1318 ELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRT 1377 EL+RQ+EEE+KAK+A+AHA+Q+ RHDCDLLREQ+EEE EA+AELQR LSKAN+EVAQWR+ Sbjct: 1363 ELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRS 1422 Query: 1378 KYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLE 1437 KYE DAIQRTEELEEAKKKLA RLQEAEE E AN+KC+SLEK K RLQ E ED+ +LE Sbjct: 1423 KYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1482 Query: 1438 RSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVD 1497 R+ +A A LDKKQR+ ++ L E +++ +E Q ELEAAQ+ESR L TELF++R+ +EE ++ Sbjct: 1483 RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALE 1542 Query: 1498 QLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEH 1557 LETL+RENKNLQEEISDLT+Q++ +GK++QE EKTKK +E EKS++Q ALEE EG+LE Sbjct: 1543 ALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALEL 1602 Query: 1558 EESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617 EE+K LR+QLELSQVK+E+DRK+ EKDEE L+RN QRA E+LQ+ LDAE R+RN+ALR Sbjct: 1603 EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALR 1662 Query: 1618 LKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAI 1677 LKKKMEGDLN++E+QLGH+ RQ E Q R +Q QLK+ Q D+ R +L EQ Sbjct: 1663 LKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQA 1722 Query: 1678 VERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEAD 1737 +ERR LL ELEE++ ALEQ ER+RRL+EQELL+A++R+ LLHSQNT L+N KKKLEAD Sbjct: 1723 LERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEAD 1782 Query: 1738 IAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797 +AQ EVE + QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK LEQTV++L Sbjct: 1783 LAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVREL 1842 Query: 1798 QHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQ 1857 Q RL+EAEQ AL+GGKKQ+QKLE +VRELE ELD EQK+ AEALKG K+ER+VKE+ YQ Sbjct: 1843 QARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQ 1902 Query: 1858 AEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIA 1917 AEED KN+ R+QDLVDKLQ+KVKSYKRQ EEAE+QANT L++ R+ QHEL++A ERAD+A Sbjct: 1903 AEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMA 1962 Query: 1918 ESQVNKLRAKSRDVGSQKMEE 1938 E+Q NKLRA++RD K +E Sbjct: 1963 ETQANKLRARTRDALGPKHKE 1983 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 2311 bits (5990), Expect = 0.0 Identities = 1160/1934 (59%), Positives = 1522/1934 (78%), Gaps = 10/1934 (0%) Query: 6 EMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTREND-KVIVKT 64 +++ GEAA +LR+ E E + Q D KK C++ D + Y++ ++ E+D VIV+T Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81 Query: 65 LDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124 D L++ D++ MNPP+F+ IEDMAM+THL+E +VL+ LK RY WMIYTYSGLFCV Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141 Query: 125 TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAG 184 T+NPYKWLPVY+ EV+AAY+GK+R EAPPHIF++++NA+Q ML +R+NQSIL TGESGAG Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201 Query: 185 KTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244 KTVN+K +IQYFATIA + +K+ QG LEDQI+QAN +LEAFGNAKT+RNDNSS Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKK------QGALEDQIMQANTILEAFGNAKTLRNDNSS 255 Query: 245 RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLL 304 RFGKFIR+HFGA G L+S DI+ YLLEKSRV FQ + ER+YHIFYQI+S +K EL DLLL Sbjct: 256 RFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLL 314 Query: 305 ISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNM 364 +S NP DF F S G VTV S+DD+EELLAT+ A+DILGF +EK G YKLTGA+MH+GNM Sbjct: 315 VSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNM 374 Query: 365 KFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTN 424 KFKQK REEQ E DGTE ADKA +LMG+NS+E++K L PR+KVGNEYVT+GQ ++QVT Sbjct: 375 KFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTC 434 Query: 425 SVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTN 484 +VGAL+K++YE+MF W+V RIN+ LD K RQ+FIG+LDI GFEI ++NSLEQLCINFTN Sbjct: 435 AVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTN 494 Query: 485 EKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPK 544 EKLQQFFN HMFVLEQEEYKKE IEW I FG+DL ACI+LIEKPMGI SILEEECMFPK Sbjct: 495 EKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPK 554 Query: 545 ATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLN 604 ATD +FK KL+D H GKS + QKPKP K K EAHF LVHYAG V YNI+GWL+KNKD LN Sbjct: 555 ATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLN 614 Query: 605 ETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMT 664 ETVV ++QKSS +LL+ LF NY ++ G KK +KKG+SFQTV+++ +ENLNKLMT Sbjct: 615 ETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMT 672 Query: 665 NLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724 NL+ST PHFVRC+ PN K PG++D YLV+ QLRCNGVLEG RICR+GFP+R+ YADFKQ Sbjct: 673 NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732 Query: 725 RYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEK 784 RY ILN P+ +F+ S+ A+E+LL S+++D Q+RFG TKVFFKAG LG LE +RDE+ Sbjct: 733 RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792 Query: 785 LVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLL 844 L + T QA +G LMR++F+K++E RD++ IQ+NIR+FM VK+WPWM LFFKIKPL+ Sbjct: 793 LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852 Query: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904 KS+E +E+A +KE+ + ++ L +SE +R+EL+ K VSL QEKNDL LQ+Q+E E L + Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912 Query: 905 AEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELT 964 EE+CE LIKSKI LEA+VKEL+ER+EEEEE+NSEL A+ R LED+C LK++IDDLE Sbjct: 913 VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972 Query: 965 LTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGL 1024 L K EKEK TE+KVKNL+EE+ L E+ISKL + K +QEAHQQTLDDL +EE+K++ L Sbjct: 973 LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032 Query: 1025 IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKL 1084 K N KLEQQ D+LEG+LEQE+K R + ER KLEG+LK+++ES+ +LE+ ++ + E+L Sbjct: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092 Query: 1085 KKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLA 1144 +KKE ELSQ+ +K+++E+ Q QK +KELQ +I++L+E++EAE T RAK+E++R+DL Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152 Query: 1145 RELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSV 1204 ++L +++ERLEE G++ AQ+E+ KK+E +FQK+ RD+EEATL E T+A+L+K+ ADS+ Sbjct: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212 Query: 1205 AELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIK 1264 AEL Q++NLQ+VKQKLEK+KS+L++E+DD+ + +E ++++K+N E+ C E++ E Sbjct: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272 Query: 1265 AKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQME 1324 AK ++ TQL +DL QK +L +++GE R+EEKE+LI+QL++ K T+Q+E+L+ Q+E Sbjct: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332 Query: 1325 EETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAI 1384 +ETK+++A+AHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + I Sbjct: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392 Query: 1385 QRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACA 1444 QRTE+LE+AKK+LA RLQEA E AN++ ASLE+ + +LQ E+ D + DL + +A A Sbjct: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452 Query: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504 LD+KQ K LA+WKQK +ESQA L+A+QKE ++LSTEL K++N YEE + ETLRR Sbjct: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512 Query: 1505 ENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILR 1564 ENKNLQEEIS+LT Q+ E KNL E EK KKL+E+EK+++QV LEE EG+LE ESKIL Sbjct: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572 Query: 1565 VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEG 1624 QLEL + K+EL+RK+ EKDEEIE +R Q ++LQS LD+E +SR + RLKKKME Sbjct: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632 Query: 1625 DLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGL 1684 DLNEME+QL +NRQ++E K L +Q Q+KD Q+ LDD+ + N DLKEQ+A+ ERRN L Sbjct: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692 Query: 1685 LLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAE 1744 L ELE+++ EQTER RRLSE+ELL+A++R+ L ++QNTSL++ KKKLEAD+A+ Q E Sbjct: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752 Query: 1745 VENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804 E +QE +NAEEKAKKA +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EA Sbjct: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812 Query: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864 EQ+AL G +KQIQKLE+RVRELE EL+ E +R AEA +GA + ER +KE+TYQAEED KN Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872 Query: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKL 1924 + R+Q +DKLQ KV++YK+Q E AE QAN LS+ ++ QHEL E ERA++AESQVNKL Sbjct: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932 Query: 1925 RAKSRDVGSQKMEE 1938 + K+R+ G + EE Sbjct: 1933 KIKAREFGKKVQEE 1946 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 1388 bits (3592), Expect = 0.0 Identities = 762/1922 (39%), Positives = 1167/1922 (60%), Gaps = 25/1922 (1%) Query: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92 +K+ +V K+ + I+ + D+V+V+ +++ + +T+ D + MNPPKF K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQ-- 210 PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+T Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211 Query: 211 --PGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 268 P G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271 Query: 269 LLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDD 327 LLEKSR Q ER++HIFY +++ K ++ DLLL N ++ F+S G V + + D Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQD 329 Query: 328 SEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAG 387 E T A+ I+GFS EE++ I K+ +V+ GN+ FK+++ +QA A K Sbjct: 330 DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVC 389 Query: 388 YLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQ 447 +LMG+N + + + PR+KVG + V K Q +Q +V ALAKA YE++F W++TR+N+ Sbjct: 390 HLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNK 449 Query: 448 QLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 506 LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++E Sbjct: 450 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 509 Query: 507 GIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 563 GIEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G Sbjct: 510 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHP 568 Query: 564 NFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF 623 FQKPK K K E FS++HYAG VDYN + WL KN DPLN+ V L SS K ++ L+ Sbjct: 569 KFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 624 SNYAG-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRC 676 + A+ +S KKG F+TV +++E L KLMT LR+T P+FVRC Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRC 685 Query: 677 LIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPE 736 +IPN K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+ Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745 Query: 737 GQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVC 796 G F+D K A ++ ++++D +R G +K+FF+ G+L LEE RD K+ ++ + QA+C Sbjct: 746 G-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMC 804 Query: 797 RGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATM 856 RGYL R F K ++ ++ IQ N +++ +++W W LF K+KPLL+ E+EM Sbjct: 805 RGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAK 864 Query: 857 KEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSK 916 +++ ++TKE ++E KELE+K L +EKN LQ Q+Q+ETE +AEE L K Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924 Query: 917 ILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATE 976 LE + E+ RLEEEE+ +L A+++ + + L+ +++ E K++ EK E Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984 Query: 977 NKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTD 1036 K+K L +E+ +++ +KL+KE+K L+E +L EE+K L K+ K E Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044 Query: 1037 DLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQA 1096 +LE L++E+K R +LE+ KRKLEGD E I DL+ +++ +L KKE EL A Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104 Query: 1097 KIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156 ++DDE KKI+EL+ I +L+E++++E R K EKQ+ DL ELE + LE+ Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164 Query: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQR 1216 +T+ Q E+ KRE E +++ L+E T HEA +R+K A +V EL EQ++ +R Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224 Query: 1217 VKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHD 1276 K L+K K L+ E D+A + L ++K +E + +E Q E+++K + + Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284 Query: 1277 LNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHA 1336 LN + +LQ + ++ + E E +L K +L+ QL++ + ++EET+ K ++ Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344 Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396 L+ + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKR 1403 Query: 1397 LAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKV 1456 + ++ + E + LEKTK RLQ E++DL+ DL+ + L+KKQR FD++ Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463 Query: 1457 LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516 LAE K + E + A+ E+R T+ + A EE ++ E L R NK L+ E+ DL Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523 Query: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576 + GKN+ E EK+K+ +E + +++ LEE+E L+ E LR+++ + +K + Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583 Query: 1577 DRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHS 1636 +R + +DE+ E+ +R QR ++ L+ E + R A KKK+EGDL ++E+Q + Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643 Query: 1637 NRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVAL 1696 + E K LR +Q Q+KD Q L+DA S +++ E++ L +L +++ L Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703 Query: 1697 EQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAE 1756 ER R+ ++ E + ++ + S +L + K++LEA IAQ + E+E Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763 Query: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1816 ++ +KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1823 Query: 1817 QKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQ 1876 LE ++ +LE +++ E + A K + ++K+KE+ Q E++ K + ++ +K Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883 Query: 1877 AKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKM 1936 A+VK KRQ EEAEE++ + R++Q EL+EA E + +VN L++K R Q+ Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1943 Query: 1937 EE 1938 + Sbjct: 1944 SQ 1945 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 1387 bits (3591), Expect = 0.0 Identities = 761/1913 (39%), Positives = 1164/1913 (60%), Gaps = 25/1913 (1%) Query: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92 +K+ +V K+ + I+ + D+V+V+ +++ + +T+ D + MNPPKF K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQ-- 210 PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+T Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211 Query: 211 --PGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 268 P G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271 Query: 269 LLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDD 327 LLEKSR Q ER++HIFY +++ K ++ DLLL N ++ F+S G V + + D Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQD 329 Query: 328 SEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAG 387 E T A+ I+GFS EE++ I K+ +V+ GN+ FK+++ +QA A K Sbjct: 330 DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVC 389 Query: 388 YLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQ 447 +LMG+N + + + PR+KVG + V K Q +Q +V ALAKA YE++F W++TR+N+ Sbjct: 390 HLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNK 449 Query: 448 QLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 506 LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++E Sbjct: 450 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 509 Query: 507 GIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSN 563 GIEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G Sbjct: 510 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHP 568 Query: 564 NFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF 623 FQKPK K K E FS++HYAG VDYN + WL KN DPLN+ V L SS K ++ L+ Sbjct: 569 KFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 624 SNYAG-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRC 676 + A+ +S KKG F+TV +++E L KLMT LR+T P+FVRC Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRC 685 Query: 677 LIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPE 736 +IPN K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+ Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745 Query: 737 GQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVC 796 G F+D K A ++ ++++D +R G +K+FF+ G+L LEE RD K+ ++ + QA+C Sbjct: 746 G-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMC 804 Query: 797 RGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATM 856 RGYL R F K ++ ++ IQ N +++ +++W W LF K+KPLL+ E+EM Sbjct: 805 RGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAK 864 Query: 857 KEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSK 916 +++ ++TKE ++E KELE+K L +EKN LQ Q+Q+ETE +AEE L K Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924 Query: 917 ILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATE 976 LE + E+ RLEEEE+ +L A+++ + + L+ +++ E K++ EK E Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984 Query: 977 NKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTD 1036 K+K L +E+ +++ +KL+KE+K L+E +L EE+K L K+ K E Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044 Query: 1037 DLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQA 1096 +LE L++E+K R +LE+ KRKLEGD E I DL+ +++ +L KKE EL A Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104 Query: 1097 KIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156 ++DDE KKI+EL+ I +L+E++++E R K EKQ+ DL ELE + LE+ Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164 Query: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQR 1216 +T+ Q E+ KRE E +++ L+E T HEA +R+K A +V EL EQ++ +R Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224 Query: 1217 VKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHD 1276 K L+K K L+ E D+A + L ++K +E + +E Q E+++K + + Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284 Query: 1277 LNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHA 1336 LN + +LQ + ++ + E E +L K +L+ QL++ + ++EET+ K ++ Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344 Query: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396 L+ + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKR 1403 Query: 1397 LAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKV 1456 + ++ + E + LEKTK RLQ E++DL+ DL+ + L+KKQR FD++ Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463 Query: 1457 LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516 LAE K + E + A+ E+R T+ + A EE ++ E L R NK L+ E+ DL Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523 Query: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576 + GKN+ E EK+K+ +E + +++ LEE+E L+ E LR+++ + +K + Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583 Query: 1577 DRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHS 1636 +R + +DE+ E+ +R QR ++ L+ E + R A KKK+EGDL ++E+Q + Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643 Query: 1637 NRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVAL 1696 + E K LR +Q Q+KD Q L+DA S +++ E++ L +L +++ L Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703 Query: 1697 EQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAE 1756 ER R+ ++ E + ++ + S +L + K++LEA IAQ + E+E Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763 Query: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1816 ++ +KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1823 Query: 1817 QKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQ 1876 LE ++ +LE +++ E + A K + ++K+KE+ Q E++ K + ++ +K Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883 Query: 1877 AKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929 A+VK KRQ EEAEE++ + R++Q EL+EA E + +VN L++K R Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936 Score = 219 bits (559), Expect = 2e-56 Identities = 221/911 (24%), Positives = 418/911 (45%), Gaps = 120/911 (13%) Query: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 EE+++ KE EL + + + + + ++K +L L+E+++AE L A+ E+ R Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917 Query: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 LA + +E+ E L E + + ++ +AE RKK Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 955 Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 A + +L EQ++ + +QKL+ EK + +I + I + + + + + +E++ Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1015 Query: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 S++ ++ + +L K + ++ EL R++++E KS+Q +LE+LK Sbjct: 1016 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE-------KSRQ----ELEKLK 1064 Query: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 R++E + + LQ+ + L+ Q +++E ELQ AL++ + E+AQ + Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAE---LKMQLAKKEE---ELQAALARLDDEIAQ-----K 1113 Query: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 +A+++ ELE + + +E+ ++ + EK K+ L E+E L +LE + Sbjct: 1114 NNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166 Query: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 + AT + + ++ + K+ LDE EA +E R K A EE+ +QLE Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEELTEQLE 1220 Query: 1501 TLRRENKNL-------QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553 +R NL ++E +DL ++ G+ QE E KK +E + +LQ + E Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1280 Query: 1554 SLEHEESKILRVQLELSQVK---SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610 + K+ ++Q E+ V +E + K I+ +++ L Q E LQ E R Sbjct: 1281 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE----ETR 1336 Query: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670 + + +++E + N ++ QL ++H+ T+ QL DS+ L D + E Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396 Query: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730 L+E ++ L ++ EE A ++ E+T+ +QEL D V L +Q + N Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL---DDLVVDLDNQRQLVSNL 1453 Query: 1731 KKKLEADIAQCQAEVENS----IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786 +KK + Q AE +N E AE +A++ T A +A L++ + LER Sbjct: 1454 EKK-QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512 Query: 1787 KKNLEQTVKDLQHRLDEAEQLA--LKGGKK----QIQKLENRVRELENELDVEQKR---- 1836 K L+ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL + Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572 Query: 1837 --GAEALKGAHKYERKVKEMTYQAEEDHKNILR--------LQD----------LVDKLQ 1876 +ALKG ++ER ++ Q EE + + R L+D KL+ Sbjct: 1573 EVNMQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630 Query: 1877 AKVKSYKRQA-------EEAEEQANTQLSRCRRVQHELEEAAERAD--IAESQVNKLRAK 1927 +K + QA EEA +Q ++ + Q ELE+A D A ++ N+ +AK Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690 Query: 1928 SRDVGSQKMEE 1938 S + +++E Sbjct: 1691 SLEADLMQLQE 1701 Score = 163 bits (412), Expect = 2e-39 Identities = 173/814 (21%), Positives = 350/814 (42%), Gaps = 121/814 (14%) Query: 847 AEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAE 906 A+ E+E+ +K+ + EE EA+ +E+ +K ++E TE L + Sbjct: 1177 AKREQEVTVLKKALD---EETRSHEAQVQEMRQKHAQAVEEL----------TEQLEQFK 1223 Query: 907 ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT 966 L K+K LE + +L L + E+ KK+ LE + L+ D E Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283 Query: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLI 1025 ++ + H +N+V++++ + E KL K+ SL Q T + LQ E K+N Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343 Query: 1026 KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLK 1085 K+ +LE++ + L+ L++E + + +LER L L S++ + D + + +EE K Sbjct: 1344 KLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402 Query: 1086 KKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR---SD 1142 + + E+ L + +++ + +K LQ +++L +++ + L + +EK++ Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462 Query: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202 L E + IS + + A+ + + + + EA + E T L+ + D Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522 Query: 1203 SVA---ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259 V+ ++G+ + L++ K+ LE + E+K +++++ ++A +K +E + ++ Q Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582 Query: 1260 FS-EIKAKDEQ--------QTQL------IHDLNMQKARLQTQNGELSHRVEEKESLISQ 1304 F +++A+DEQ Q QL + D Q+A +L +++ E Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1642 Query: 1305 LTKSKQALTQQLEELKRQM----------------------EEETKAKNAMAHALQ---- 1338 K ++ +QL +L+ QM E E KAK+ A +Q Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702 Query: 1339 -----SSRHDCDLLREQYEEE-----------QEAKAELQRALSKANSEVAQWRTKYET- 1381 +R DL +E+ EE Q+ K L+ +++ E+ + + E Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762 Query: 1382 -----DAIQRTEELEE---AKKKLAQRLQEAEENTETAN-------------------SK 1414 A Q+ E+L ++ AQ+ + A + E N S Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822 Query: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAA 1474 A+LE +L+ +VE R+ + AT KQ+ DK L E ++++ + E Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQK--DKKLKEILLQVEDERKMAEQY 1875 Query: 1475 QKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTK 1534 ++++ + + +++ EE ++ + + + LQ E+ + TE G+ + A K+K Sbjct: 1876 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV-NALKSK 1934 Query: 1535 -------KLVEQEKSDLQVALEEVEGSLEHEESK 1561 V +S + +E +GS E +++ Sbjct: 1935 LRRGNETSFVPSRRSGGRRVIENADGSEEETDTR 1968 Score = 124 bits (311), Expect = 9e-28 Identities = 116/542 (21%), Positives = 246/542 (45%), Gaps = 47/542 (8%) Query: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460 L + E +K L+KTK+R Q + E+ +++LE+ H+ ++K +++ AE Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAET 907 Query: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520 + + + + A K+ + L L +M EE D+ + L+ E K + +++ DL EQ Sbjct: 908 ELYAEAEEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ- 965 Query: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL---EHEESKILRVQLELSQVKSELD 1577 L+E E ++ ++ EK + ++++E + + + +K+ + + L + S+L Sbjct: 966 ------LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1019 Query: 1578 RKVIEKDEE---IEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLG 1634 + E++E+ + +LK + L+ L E +SR + +LK+K+EGD ++ Q+ Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1079 Query: 1635 HSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKV 1694 Q+AE + L + +L+ + LDD + + +++ +E L E+L+ + Sbjct: 1080 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1139 Query: 1695 ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRN 1754 A + E+ +R D + ++ L + E+E+++ + Sbjct: 1140 ARNKAEKQKR-------DLGEELEAL---------------------KTELEDTLDSTAT 1171 Query: 1755 AEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813 +E K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K Sbjct: 1172 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1231 Query: 1814 KQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVD 1873 + Q LE +L EL V + E K E +V+E+ + + + L D V Sbjct: 1232 NK-QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290 Query: 1874 KLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGS 1933 KLQ +V+S EAE +A + +L++ E Q + K R + Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350 Query: 1934 QK 1935 ++ Sbjct: 1351 ER 1352 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 1387 bits (3591), Expect = 0.0 Identities = 761/1918 (39%), Positives = 1167/1918 (60%), Gaps = 24/1918 (1%) Query: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92 +K+ +V K+ + I+ + D+V+V+ +++ + +T+ D + MNPPKF K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212 PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+T Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209 Query: 213 KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272 + G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEK Sbjct: 210 -ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268 Query: 273 SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331 SR Q ER++HIFY +++ K ++ DLLL N ++ F+S G V + + D E Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 326 Query: 332 LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391 T A+ I+GFS EE++ I K+ +V+ GN+ FK+++ +QA A K +LMG Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 392 LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450 +N + + + PR+KVG + V K Q +Q +V ALAKA YE++F W++TR+N+ LD Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 451 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510 T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 511 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567 FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565 Query: 568 PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYA 627 PK K K E FS++HYAG VDYN + WL KN DPLN+ V L SS K ++ L+ + Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623 Query: 628 G-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPN 680 A+ +S KKG F+TV +++E L KLMT LR+T P+FVRC+IPN Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682 Query: 681 ETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFI 740 K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+G F+ Sbjct: 683 HEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FM 741 Query: 741 DSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYL 800 D K A ++ ++++D +R G +K+FF+ G+L LEE RD K+ ++ + QA+CRGYL Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801 Query: 801 MRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDF 860 R F K ++ ++ IQ N +++ +++W W LF K+KPLL+ E+EM +++ Sbjct: 802 ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861 Query: 861 ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLE 920 ++TKE ++E KELE+K L +EKN LQ Q+Q+ETE +AEE L K LE Sbjct: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921 Query: 921 AKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVK 980 + E+ RLEEEE+ +L A+++ + + L+ +++ E K++ EK E K+K Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981 Query: 981 NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040 L +E+ +++ +KL+KE+K L+E +L EE+K L K+ K E +LE Sbjct: 982 KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041 Query: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD 1100 L++E+K R +LE+ KRKLEGD E I DL+ +++ +L KKE EL A++DD Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101 Query: 1101 EQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGA 1160 E KKI+EL+ I +L+E++++E R K EKQ+ DL ELE + LE+ + Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161 Query: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220 T+ Q E+ KRE E +++ L+E T HEA +R+K A +V EL EQ++ +R K Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221 Query: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280 L+K K L+ E D+A + L ++K +E + +E Q E+++K + +LN + Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281 Query: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS 1340 +LQ + ++ + E E +L K +L+ QL++ + ++EET+ K ++ L+ Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341 Query: 1341 RHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400 + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKE 1400 Query: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460 ++ + E + LEKTK RLQ E++DL+ DL+ + L+KKQR FD++LAE Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460 Query: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520 K + E + A+ E+R T+ + A EE ++ E L R NK L+ E+ DL Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520 Query: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKV 1580 + GKN+ E EK+K+ +E + +++ LEE+E L+ E LR+++ + +K + +R + Sbjct: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDL 1580 Query: 1581 IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640 +DE+ E+ +R QR ++ L+ E + R A KKK+EGDL ++E+Q + + Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640 Query: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700 E K LR +Q Q+KD Q L+DA S +++ E++ L +L +++ L E Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 1700 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 R R+ ++ E + ++ + S +L + K++LEA IAQ + E+E ++ + Sbjct: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 ++ +LE +++ E + A K + ++K+KE+ Q E++ K + ++ +K A+VK Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 KRQ EEAEE++ + R++Q EL+EA E + +VN L++K R Q+ + Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQETSQ 1938 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 1387 bits (3590), Expect = 0.0 Identities = 760/1909 (39%), Positives = 1164/1909 (60%), Gaps = 24/1909 (1%) Query: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92 +K+ +V K+ + I+ + D+V+V+ +++ + +T+ D + MNPPKF K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212 PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+T Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209 Query: 213 KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272 + G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEK Sbjct: 210 -ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268 Query: 273 SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331 SR Q ER++HIFY +++ K ++ DLLL N ++ F+S G V + + D E Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 326 Query: 332 LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391 T A+ I+GFS EE++ I K+ +V+ GN+ FK+++ +QA A K +LMG Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 392 LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450 +N + + + PR+KVG + V K Q +Q +V ALAKA YE++F W++TR+N+ LD Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 451 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510 T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 511 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567 FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565 Query: 568 PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYA 627 PK K K E FS++HYAG VDYN + WL KN DPLN+ V L SS K ++ L+ + Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623 Query: 628 G-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPN 680 A+ +S KKG F+TV +++E L KLMT LR+T P+FVRC+IPN Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682 Query: 681 ETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFI 740 K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+G F+ Sbjct: 683 HEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FM 741 Query: 741 DSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYL 800 D K A ++ ++++D +R G +K+FF+ G+L LEE RD K+ ++ + QA+CRGYL Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801 Query: 801 MRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDF 860 R F K ++ ++ IQ N +++ +++W W LF K+KPLL+ E+EM +++ Sbjct: 802 ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861 Query: 861 ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLE 920 ++TKE ++E KELE+K L +EKN LQ Q+Q+ETE +AEE L K LE Sbjct: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921 Query: 921 AKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVK 980 + E+ RLEEEE+ +L A+++ + + L+ +++ E K++ EK E K+K Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981 Query: 981 NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040 L +E+ +++ +KL+KE+K L+E +L EE+K L K+ K E +LE Sbjct: 982 KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041 Query: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD 1100 L++E+K R +LE+ KRKLEGD E I DL+ +++ +L KKE EL A++DD Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101 Query: 1101 EQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGA 1160 E KKI+EL+ I +L+E++++E R K EKQ+ DL ELE + LE+ + Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161 Query: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220 T+ Q E+ KRE E +++ L+E T HEA +R+K A +V EL EQ++ +R K Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221 Query: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280 L+K K L+ E D+A + L ++K +E + +E Q E+++K + +LN + Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281 Query: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS 1340 +LQ + ++ + E E +L K +L+ QL++ + ++EET+ K ++ L+ Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341 Query: 1341 RHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400 + + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKE 1400 Query: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460 ++ + E + LEKTK RLQ E++DL+ DL+ + L+KKQR FD++LAE Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460 Query: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520 K + E + A+ E+R T+ + A EE ++ E L R NK L+ E+ DL Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520 Query: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKV 1580 + GKN+ E EK+K+ +E + +++ LEE+E L+ E LR+++ + +K + +R + Sbjct: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDL 1580 Query: 1581 IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640 +DE+ E+ +R QR ++ L+ E + R A KKK+EGDL ++E+Q + + Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640 Query: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700 E K LR +Q Q+KD Q L+DA S +++ E++ L +L +++ L E Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 1700 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 R R+ ++ E + ++ + S +L + K++LEA IAQ + E+E ++ + Sbjct: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 ++ +LE +++ E + A K + ++K+KE+ Q E++ K + ++ +K A+VK Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929 KRQ EEAEE++ + R++Q EL+EA E + +VN L++K R Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929 Score = 219 bits (559), Expect = 2e-56 Identities = 221/911 (24%), Positives = 418/911 (45%), Gaps = 120/911 (13%) Query: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 EE+++ KE EL + + + + + ++K +L L+E+++AE L A+ E+ R Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 LA + +E+ E L E + + ++ +AE RKK Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 948 Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 A + +L EQ++ + +QKL+ EK + +I + I + + + + + +E++ Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008 Query: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 S++ ++ + +L K + ++ EL R++++E KS+Q +LE+LK Sbjct: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE-------KSRQ----ELEKLK 1057 Query: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 R++E + + LQ+ + L+ Q +++E ELQ AL++ + E+AQ + Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAE---LKMQLAKKEE---ELQAALARLDDEIAQ-----K 1106 Query: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 +A+++ ELE + + +E+ ++ + EK K+ L E+E L +LE + Sbjct: 1107 NNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159 Query: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 + AT + + ++ + K+ LDE EA +E R K A EE+ +QLE Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEELTEQLE 1213 Query: 1501 TLRRENKNL-------QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553 +R NL ++E +DL ++ G+ QE E KK +E + +LQ + E Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273 Query: 1554 SLEHEESKILRVQLELSQVK---SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610 + K+ ++Q E+ V +E + K I+ +++ L Q E LQ E R Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE----ETR 1329 Query: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670 + + +++E + N ++ QL ++H+ T+ QL DS+ L D + E Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389 Query: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730 L+E ++ L ++ EE A ++ E+T+ +QEL D V L +Q + N Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL---DDLVVDLDNQRQLVSNL 1446 Query: 1731 KKKLEADIAQCQAEVENS----IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786 +KK + Q AE +N E AE +A++ T A +A L++ + LER Sbjct: 1447 EKK-QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505 Query: 1787 KKNLEQTVKDLQHRLDEAEQLA--LKGGKK----QIQKLENRVRELENELDVEQKR---- 1836 K L+ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL + Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565 Query: 1837 --GAEALKGAHKYERKVKEMTYQAEEDHKNILR--------LQD----------LVDKLQ 1876 +ALKG ++ER ++ Q EE + + R L+D KL+ Sbjct: 1566 EVNMQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623 Query: 1877 AKVKSYKRQA-------EEAEEQANTQLSRCRRVQHELEEAAERAD--IAESQVNKLRAK 1927 +K + QA EEA +Q ++ + Q ELE+A D A ++ N+ +AK Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683 Query: 1928 SRDVGSQKMEE 1938 S + +++E Sbjct: 1684 SLEADLMQLQE 1694 Score = 163 bits (412), Expect = 2e-39 Identities = 173/814 (21%), Positives = 350/814 (42%), Gaps = 121/814 (14%) Query: 847 AEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAE 906 A+ E+E+ +K+ + EE EA+ +E+ +K ++E TE L + Sbjct: 1170 AKREQEVTVLKKALD---EETRSHEAQVQEMRQKHAQAVEEL----------TEQLEQFK 1216 Query: 907 ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT 966 L K+K LE + +L L + E+ KK+ LE + L+ D E Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276 Query: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLI 1025 ++ + H +N+V++++ + E KL K+ SL Q T + LQ E K+N Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1336 Query: 1026 KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLK 1085 K+ +LE++ + L+ L++E + + +LER L L S++ + D + + +EE K Sbjct: 1337 KLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395 Query: 1086 KKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR---SD 1142 + + E+ L + +++ + +K LQ +++L +++ + L + +EK++ Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455 Query: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202 L E + IS + + A+ + + + + EA + E T L+ + D Sbjct: 1456 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515 Query: 1203 SVA---ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259 V+ ++G+ + L++ K+ LE + E+K +++++ ++A +K +E + ++ Q Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575 Query: 1260 FS-EIKAKDEQ--------QTQL------IHDLNMQKARLQTQNGELSHRVEEKESLISQ 1304 F +++A+DEQ Q QL + D Q+A +L +++ E Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1635 Query: 1305 LTKSKQALTQQLEELKRQM----------------------EEETKAKNAMAHALQ---- 1338 K ++ +QL +L+ QM E E KAK+ A +Q Sbjct: 1636 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695 Query: 1339 -----SSRHDCDLLREQYEEE-----------QEAKAELQRALSKANSEVAQWRTKYET- 1381 +R DL +E+ EE Q+ K L+ +++ E+ + + E Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755 Query: 1382 -----DAIQRTEELEE---AKKKLAQRLQEAEENTETAN-------------------SK 1414 A Q+ E+L ++ AQ+ + A + E N S Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815 Query: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAA 1474 A+LE +L+ +VE R+ + AT KQ+ DK L E ++++ + E Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQK--DKKLKEILLQVEDERKMAEQY 1868 Query: 1475 QKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTK 1534 ++++ + + +++ EE ++ + + + LQ E+ + TE G+ + A K+K Sbjct: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV-NALKSK 1927 Query: 1535 -------KLVEQEKSDLQVALEEVEGSLEHEESK 1561 V +S + +E +GS E +++ Sbjct: 1928 LRRGNETSFVPSRRSGGRRVIENADGSEEETDTR 1961 Score = 124 bits (311), Expect = 9e-28 Identities = 116/542 (21%), Positives = 246/542 (45%), Gaps = 47/542 (8%) Query: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460 L + E +K L+KTK+R Q + E+ +++LE+ H+ ++K +++ AE Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAET 900 Query: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520 + + + + A K+ + L L +M EE D+ + L+ E K + +++ DL EQ Sbjct: 901 ELYAEAEEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ- 958 Query: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL---EHEESKILRVQLELSQVKSELD 1577 L+E E ++ ++ EK + ++++E + + + +K+ + + L + S+L Sbjct: 959 ------LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1012 Query: 1578 RKVIEKDEE---IEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLG 1634 + E++E+ + +LK + L+ L E +SR + +LK+K+EGD ++ Q+ Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072 Query: 1635 HSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKV 1694 Q+AE + L + +L+ + LDD + + +++ +E L E+L+ + Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132 Query: 1695 ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRN 1754 A + E+ +R D + ++ L + E+E+++ + Sbjct: 1133 ARNKAEKQKR-------DLGEELEAL---------------------KTELEDTLDSTAT 1164 Query: 1755 AEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813 +E K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224 Query: 1814 KQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVD 1873 + Q LE +L EL V + E K E +V+E+ + + + L D V Sbjct: 1225 NK-QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283 Query: 1874 KLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGS 1933 KLQ +V+S EAE +A + +L++ E Q + K R + Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343 Query: 1934 QK 1935 ++ Sbjct: 1344 ER 1345 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 1375 bits (3559), Expect = 0.0 Identities = 760/1920 (39%), Positives = 1166/1920 (60%), Gaps = 26/1920 (1%) Query: 27 AQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKF 85 A + +KK ++ + + I+ D+V+V+ ++ + +N D + MNPPKF Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84 Query: 86 DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRG 145 K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ YRG Sbjct: 85 SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144 Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDK 205 KKR E PPHI++IS++AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + Sbjct: 145 KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204 Query: 206 KKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADI 265 +K+ + G LE Q++QANP+LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+I Sbjct: 205 RKDHN---IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261 Query: 266 ETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVAS 324 ETYLLEKSR Q ER++HIFYQ++S L DLLL N ++ F+S G + + Sbjct: 262 ETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPG 319 Query: 325 IDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 384 D + T A+ I+GFS EE + + K+ +V+ +GN+ FK+++ +QA VA Sbjct: 320 QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379 Query: 385 KAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTR 444 K +L+G+N E + + PR+KVG +YV K Q +Q +V ALAKA YE++F W+V R Sbjct: 380 KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439 Query: 445 INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 503 IN+ LD TK+ FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY Sbjct: 440 INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499 Query: 504 KKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 560 ++EGIEW FIDFG+DL CI+LIE+P G+ ++L+EEC FPKATD +F KL Q G Sbjct: 500 QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558 Query: 561 KSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLS 620 + FQKP+ K KA+ F ++HYAG VDY WL KN DPLN+ V L +SS + ++ Sbjct: 559 SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616 Query: 621 FLFSNY--------AGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPH 672 L+ + T + GS K K F+TV +++E+L KLM LR+T+P+ Sbjct: 617 ELWKDVDRIVGLDQVTGMTETAFGSAY--KTKKGMFRTVGQLYKESLTKLMATLRNTNPN 674 Query: 673 FVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNAS 732 FVRC+IPN K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL + Sbjct: 675 FVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN 734 Query: 733 AIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTST 792 AIP+G F+D K A E+++ ++++D +R G +K+FF+AG+L LEE RD K+ ++ Sbjct: 735 AIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF 793 Query: 793 QAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKE 852 QAVCRGYL R F K ++ ++ +Q N +++ ++HW W +F K+KPLL+ E+E Sbjct: 794 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE 853 Query: 853 MATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGL 912 + E+ + KE+ + E +E+E K LL+EKN L Q+Q+ETE +AEE L Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL 913 Query: 913 IKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEK 972 K LE + +L R+EEEEE N L +K+ ++ L+ +D+ E K++ EK Sbjct: 914 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK 973 Query: 973 HATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLE 1032 E K+K + EE+ LE+ SK KEKK +++ + L EE+K L KI K E Sbjct: 974 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE 1033 Query: 1033 QQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELS 1092 DLE L++E+K R +LE+AKRKL+G+ Q+ I +L+ +++ +L KKE EL Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093 Query: 1093 QLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISE 1152 A+ DDE +H K ++ELQA+I EL+E+ E+E R K EKQ+ DL+ ELE + Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153 Query: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212 LE+ T+AQ E+ KRE E ++++ LEE T HEA +R++ A ++ EL EQ++ Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213 Query: 1213 NLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272 +R K LEK K L+ + ++A ++ L + K+ E + ++ Q E+ AK + + Sbjct: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR 1273 Query: 1273 LIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNA 1332 L +L + ++LQ + +S +EE E + K +L QL++ + ++EET+ K Sbjct: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333 Query: 1333 MAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE 1392 ++ ++ + + L+EQ EEE+EA+ L++ + S++A + K + D + E LEE Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEE 1392 Query: 1393 AKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRN 1452 AKKKL + + + E LEKTK RLQ E++DL DL+ + L+KKQ+ Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452 Query: 1453 FDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEE 1512 FD++LAE K E + A+ E+R T+ + A EE ++ E R+NK L+ + Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRAD 1512 Query: 1513 ISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQV 1572 + DL + GKN+ E EK+K+ +EQ+ +++ LEE+E L+ E LR+++ + + Sbjct: 1513 MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572 Query: 1573 KSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQ 1632 K++ +R + +DE+ E+ KR + L++ L+ E + R A+ KKKME DL ++E Q Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632 Query: 1633 LGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM 1692 + +N+ E K LR +Q Q+KD Q L++A S +++ Q E++ L E+ ++ Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692 Query: 1693 KVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQES 1752 + L +ER RR +EQE + +D + S ++L++ K++LEA IAQ + E+E Sbjct: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNM 1752 Query: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1812 ++ +K + EL E+ + + ++ LE+ K+L+ +L E E Sbjct: 1753 ELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812 Query: 1813 KKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLV 1872 K I LE ++ +LE +L+ E K A A K + E+K+KE+ Q E++ ++ + ++ + Sbjct: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872 Query: 1873 DKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVG 1932 +K A++K KRQ EEAEE+A + R++Q EL++A E + +V+ L+ + R G Sbjct: 1873 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG 1932 Score = 199 bits (506), Expect = 2e-50 Identities = 202/864 (23%), Positives = 397/864 (45%), Gaps = 92/864 (10%) Query: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 EE+L+ K+ EL +++ K + + ++K ++L L E+++AE L A+ E+ R Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910 Query: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200 + LA + +E+ E L + + E N+ LQ+E +KK Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQ----------------ILQNE------KKKM 948 Query: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260 + +L EQ+D + +QKL+ EK + +I M I L S + + +ED+ Sbjct: 949 QAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRI 1008 Query: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 +E ++ ++ + +L + + + +L R++++E +L K+K+ L + +L+ Sbjct: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068 Query: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380 Q+ E LQ+ D L+ Q +++E ELQ AL++ + E T ++ Sbjct: 1069 DQIAE-----------LQAQ---IDELKLQLAKKEE---ELQGALARGDDE-----TLHK 1106 Query: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440 +A++ EL+ ++ E +E+ E+ + EK K+ L E+E L +LE + Sbjct: 1107 NNALKVVRELQA-------QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159 Query: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500 A + + ++ +AE K+ L+E EA ++ R + A EE+ +QLE Sbjct: 1160 DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ------RHATALEELSEQLE 1213 Query: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560 +R NL++ L E ++ ++ K E ++ L ++E+ + E Sbjct: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EG 1271 Query: 1561 KILRVQL--ELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQS-------VLDAEIRS 1611 LRV+L + S++++ELD V EE E+ + A +L+S +L E R Sbjct: 1272 DRLRVELAEKASKLQNELDN-VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330 Query: 1612 RNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDL 1671 + + +++E + N ++ Q +K + +Q QL D++ +DD L + E L Sbjct: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL 1390 Query: 1672 KEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTK 1731 +E + + L + LEE +A ++ E+T+ +QEL D + + ++L + Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450 Query: 1732 KKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1791 KK + +A+ ++ +E AE +A++ T A +A L++ + ER K L Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510 Query: 1792 QTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKV 1851 ++DL D+ K + +LE R LE +++ E + E L Sbjct: 1511 ADMEDLMSSKDDVG--------KNVHELEKSKRALEQQVE-EMRTQLEEL---------- 1551 Query: 1852 KEMTYQAEEDHKNILRLQDLVDKLQAKV-KSYKRQAEEAEEQANTQLSRCRRVQHELEEA 1910 E QA ED K LRL+ + ++A+ + + + E+ EE+ + + R ++ ELE+ Sbjct: 1552 -EDELQATEDAK--LRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE 1608 Query: 1911 AERADIAESQVNKLRAKSRDVGSQ 1934 ++ +A + K+ +D+ +Q Sbjct: 1609 RKQRALAVASKKKMEIDLKDLEAQ 1632 Score = 158 bits (400), Expect = 4e-38 Identities = 161/735 (21%), Positives = 328/735 (44%), Gaps = 69/735 (9%) Query: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275 +VK L+ + E +++ D E L K K + VE + E++ K +Q L+ Sbjct: 840 KVKPLLQVTRQEEELQAKD-----EELLKVKEKQTK----VEGELEEMERKHQQ---LLE 887 Query: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335 + N+ +LQ + + E E + ++L KQ L + L +L+ ++EEE + + + Sbjct: 888 EKNILAEQLQAE----TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943 Query: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395 + + L EQ +EE+ A+ +LQ A +++ + + Q ++ ++E KK Sbjct: 944 EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE-KK 1002 Query: 1396 KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDK 1455 + R+ E K +L K + + + + DL L++ L+K +R D Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062 Query: 1456 VLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN-----KNLQ 1510 + + ++ E QA+++ + + EL + A D ETL + N + LQ Sbjct: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEEEL---QGALARGDD--ETLHKNNALKVVRELQ 1117 Query: 1511 EEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELS 1570 +I++L E + +AEK K+ + +E L+ LE+ + ++ + + E++ Sbjct: 1118 AQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVA 1177 Query: 1571 QVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEME 1630 ++K L+ + + +I+ +++ A E L L+ R + + + K+ +E D E+ Sbjct: 1178 ELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELA 1237 Query: 1631 IQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELE 1690 ++ + AE++ + + Q+++ + + R +L E+ + ++ EL+ Sbjct: 1238 CEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN-------ELD 1290 Query: 1691 EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVE-NSI 1749 + LE+ E+ ++ AS QL +Q T++KL Q E E NS+ Sbjct: 1291 NVSTLLEEAEKKGIKFAKDA--ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSL 1348 Query: 1750 QESRNAEEKAKKAITDAAM-----MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804 QE + EE+A+K + + +A+ KK D +E +++ ++ +KD + Sbjct: 1349 QEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL 1408 Query: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864 E+ AL K ++K +NR+++ ++L V+ + K ++K Sbjct: 1409 EEKALAYDK--LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF------------- 1453 Query: 1865 ILRLQDLVDKLQAKVKS----YKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920 D+L A+ KS Y + + AE +A + ++ + LEEA E + E Q Sbjct: 1454 --------DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQ 1505 Query: 1921 VNKLRAKSRDVGSQK 1935 +LRA D+ S K Sbjct: 1506 NKQLRADMEDLMSSK 1520 Score = 115 bits (288), Expect = 4e-25 Identities = 123/561 (21%), Positives = 262/561 (46%), Gaps = 72/561 (12%) Query: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460 L + E +K L K K++ Q +VE + ++ER H L++K +++ AE Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMERKHQQL--LEEKNILAEQLQAET 900 Query: 1461 K--QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTE 1518 + + +E +A L A ++E + L + + EE ++ + L+ E K +Q I DL E Sbjct: 901 ELFAEAEEMRARLAAKKQELEEI---LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957 Query: 1519 QIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGS---LEHEESKILRVQLELSQVKSE 1575 Q L E E ++ ++ EK + ++++E LE + SK ++ + + +E Sbjct: 958 Q-------LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010 Query: 1576 LDRKVIEKDEEIEQLK--RNSQRAAEA-LQSVLDAEIRSRNDALRLKKKMEGD------- 1625 ++ E++E+ + L RN Q + L+ L E ++R + + K+K++G+ Sbjct: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 1070 Query: 1626 LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685 + E++ Q+ Q+A+ ++ L+ + D LH ++AL+ +L+ Q+A ++ Sbjct: 1071 IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ------ 1124 Query: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745 E+ E K + + E+ +R D S+ ++ L + E+ Sbjct: 1125 -EDFESEKASRNKAEKQKR-------DLSEELEAL---------------------KTEL 1155 Query: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEA 1804 E+++ + +E K + A + + L++E ++ A ++ M++ +++L +L++A Sbjct: 1156 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA 1215 Query: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864 ++ K + Q LE +EL E+ V Q+ AE+ K + +V+E+ + E + Sbjct: 1216 KRFKANLEKNK-QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274 Query: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQ-------ANTQLSRCRRVQHELEEAAERADIA 1917 + L + KLQ ++ + EEAE++ A + S+ + Q L+E + Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334 Query: 1918 ESQVNKLRAKSRDVGSQKMEE 1938 S++ +L + + Q+ EE Sbjct: 1335 SSRIRQLEEEKNSLQEQQEEE 1355 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 1374 bits (3557), Expect = 0.0 Identities = 762/1912 (39%), Positives = 1156/1912 (60%), Gaps = 33/1912 (1%) Query: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92 +KK +V +K + ++ ++ IV+ +++ + + +N D + MNPPKF K+EDMA Sbjct: 28 AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152 +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y E+V Y+GKKR E P Sbjct: 88 ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147 Query: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212 PHI++I+D AY+ M+ DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+ Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203 Query: 213 KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272 QG LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEK Sbjct: 204 --QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEK 261 Query: 273 SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331 SR Q ER++HIFY ++S L DLLL N + F +S G VT+ D + Sbjct: 262 SRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRF--LSNGHVTIPGQQDKDMF 319 Query: 332 LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391 T A+ I+G EE++G+ ++ V+ GN+ FK+++ +QA A K +L+G Sbjct: 320 QETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLG 379 Query: 392 LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450 +N + +G+ PR+KVG +YV K Q +Q ++ ALAKA YE+MF W+V RIN+ LD Sbjct: 380 INVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDK 439 Query: 451 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510 TK+ FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW Sbjct: 440 TKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 499 Query: 511 EFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567 FIDFG+DL CI+LIEKP G I ++L+EEC FPKATD SF K+ Q G FQK Sbjct: 500 NFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQK 558 Query: 568 PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNY- 626 PK K KA+ F ++HYAG VDY WL KN DPLN+ + L +SS K +S L+ + Sbjct: 559 PKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVD 616 Query: 627 --------AG-AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCL 677 AG +ET G K +KG F+TV +++E L KLM LR+T+P+FVRC+ Sbjct: 617 RIIGLDQVAGMSETALPGAFKT---RKGM-FRTVGQLYKEQLAKLMATLRNTNPNFVRCI 672 Query: 678 IPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEG 737 IPN K G +D +LV+ QLRCNGVLEGIRICR+GFP+R+++ +F+QRY IL ++IP+G Sbjct: 673 IPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG 732 Query: 738 QFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCR 797 F+D K A ++ ++++D +R G +KVFF+AG+L LEE RD K+ ++ QA CR Sbjct: 733 -FMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCR 791 Query: 798 GYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMK 857 GYL R F K ++ ++ +Q N +++ +++W W LF K+KPLL+ + E+EM + Sbjct: 792 GYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKE 851 Query: 858 EDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKI 917 E+ + +E+ +E R E+E L+ EK LQ Q+Q+ETE +AEE L K Sbjct: 852 EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQ 911 Query: 918 LLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATEN 977 LE +L R+EEEEE L A+K+ ++ L+ +++ E K++ EK TE Sbjct: 912 ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971 Query: 978 KVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDD 1037 K+K L EE LE+ KL KEKK L++ + +L EE+K L K+ K E D Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031 Query: 1038 LEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAK 1097 LE L +E+K R +LE+ +RKLEGD + I +L+ +++ +L KKE EL A+ Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091 Query: 1098 IDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157 +++E KKI+EL+++I EL+E++E+E R K EKQ+ DL ELE + LE+ Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151 Query: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217 +T+AQ E+ KRE E +++ LEE HEA +R+K + +V EL EQ++ +RV Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211 Query: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDL 1277 K LEK K L+ E ++A+ ++ L + K + E + VE Q E++ K + ++ +L Sbjct: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271 Query: 1278 NMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHAL 1337 + +LQ + ++ + + +S S+LTK AL QL++ + ++EE + K +++ L Sbjct: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331 Query: 1338 QSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1397 + + + REQ EEE+EAK L++ ++ +++VA + K E D++ E EE K+KL Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKL 1390 Query: 1398 AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL 1457 + L+ + E + LEKTK RLQ E++DL+ DL+ + L+KKQ+ FD++L Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450 Query: 1458 AEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLT 1517 AE K + E + A+ E+R T+ + A EE ++Q L R NK + E+ DL Sbjct: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510 Query: 1518 EQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELD 1577 + GK++ E EK+K+ +EQ+ +++ LEE+E L+ E LR+++ L +K++ + Sbjct: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570 Query: 1578 RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSN 1637 R + +DE+ E+ K+ R +++ L+ E + R+ A+ +KK+E DL ++E + +N Sbjct: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630 Query: 1638 RQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALE 1697 + E K LR +Q Q+KD LDD S E++ Q E++ + E+ +++ L Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690 Query: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757 ER +R ++QE + +D + + + K++LEA IAQ + E+E + + Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750 Query: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817 + KKA + +L E+ + E ++ LE+ K+L+ +L E E K I Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810 Query: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQA 1877 LE ++ +LE +LD E K A K + E+K+K++ Q +++ +N + +D DK Sbjct: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870 Query: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929 ++K KRQ EEAEE+A + R++Q ELE+A E AD +V+ L+ K R Sbjct: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922 Score = 260 bits (665), Expect = 8e-69 Identities = 264/1195 (22%), Positives = 526/1195 (44%), Gaps = 184/1195 (15%) Query: 686 GVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA 745 GV+ H L+ V+ G + C +G+ +R +A +Q+ + ++ +N Sbjct: 766 GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825 Query: 746 S-----EKLLNSIDVDR-EQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGY 799 K+ + V R E+ + K L E R ++ TL + A Sbjct: 826 QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAE---- 881 Query: 800 LMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEA-----EKEMA 854 +++ ++ ++ + +R+ + K + ++ ++ E + E Sbjct: 882 --KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK 939 Query: 855 TMKEDFERTKEELARSEARR--------------KELEEKMV-------SLLQEKNDLQL 893 M+++ + +E+L E+ R K+LEE+ + L +EK L+ Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLED 999 Query: 894 QVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLE----- 948 ++ T NL + EE+ + L K K EA + +L ERL EE+ EL +R LE Sbjct: 1000 RIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD 1059 Query: 949 --DKCSSLKRDIDDLELTLTKVEKE--------------KHATENKVKNLSEEMTALEEN 992 D+ + L+ I +L++ L K E+E K+ K++ L +++ L+E+ Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119 Query: 993 I-------SKLTKEKKSLQEAHQ-------QTLDDLQVE-------EDKVNGLIK----- 1026 + +K K+K+ L E + TLD + E +VN L K Sbjct: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179 Query: 1027 ----------INAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND 1076 + K Q ++L LEQ K+++A+LE+AK+ LE + + L Sbjct: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239 Query: 1077 KQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKI 1136 K E K KK E +L +LQ K ++ + + K+ +LQ ++ + + + +K+ Sbjct: 1240 KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299 Query: 1137 EKQRSDLARELEEISERLEE--------ASGATSAQIEMNKKREA--EFQKMRRDLEEAT 1186 K S L +L++ E L+E ++ + E N RE E ++ + +LE+ Sbjct: 1300 TKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQI 1359 Query: 1187 LQHEATAATLRKKQADSVA--ELGEQID-----NLQRVKQ----------KLEKEKSELK 1229 A A ++KK DSV E E++ +L+ + Q KLEK K+ L+ Sbjct: 1360 ATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419 Query: 1230 MEIDDMASNIEALSKSKSNIERTCR----------TVEDQFSEIKAKDEQQTQ------- 1272 E+DD+ +++ +S N+E+ + T+ +++E + + E + + Sbjct: 1420 QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL 1479 Query: 1273 ----LIHDLNMQKARLQTQNGELSHRVEEKESL-------ISQLTKSKQALTQQLEELKR 1321 + + QKA L+ N + +E+ S + +L KSK+AL QQ+EE+K Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539 Query: 1322 QMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET 1381 Q+EE L ++ + ++AK L+ L ++ +E Sbjct: 1540 QLEE---------------------LEDELQATEDAKLRLEVNLQAMKAQ-------FER 1571 Query: 1382 DAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHT 1441 D R E+ EE KK+L ++++E E E + + +++L+ +++DL ++ ++ Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631 Query: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLET 1501 K+ R + + ++LD+++A E +++ +L M ++ ++L Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691 Query: 1502 LRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561 R + Q+E +L ++IA + A + K+ +E + L+ LEE +G+ E + Sbjct: 1692 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1751 Query: 1562 ILRVQLELSQVKSEL--DRKVIEKDEEI-EQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618 + + L++ Q+ ++L +R +K+E +QL+R ++ LQ ++ ++S+ A Sbjct: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE-MEGTVKSKYKASIT 1810 Query: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678 +E + ++E QL + ++ K +R + +LKD L +DD R+ E K+Q Sbjct: 1811 A--LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868 Query: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKK 1733 R L +LEE + ++ +RR ++EL DA++ ++ + +SL N ++ Sbjct: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923 Score = 192 bits (487), Expect = 3e-48 Identities = 197/847 (23%), Positives = 370/847 (43%), Gaps = 83/847 (9%) Query: 1106 LQFQKKIKELQARIEEL----EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGAT 1161 LQ ++ +E+ A+ EEL E+++ AE+ L ++E +S L E ++ E+L+ + Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRL-TEMETLQSQLMAEKLQLQEQLQAETELC 896 Query: 1162 SAQIEMNKK---REAEFQKMRRDLEEATLQHEATAATL---RKKQADSVAELGEQIDNLQ 1215 + E+ + ++ E +++ DLE + E L +KK ++ EL EQ++ + Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956 Query: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275 +QKL+ EK + ++ + L + + + +ED+ +E ++ Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE----- 1011 Query: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335 EEK +++L +A+ LEE R+ E++ + Sbjct: 1012 --------------------EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051 Query: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395 L+ D L +Q E Q AEL+ L+K E+ + E +A Q+ L++ ++ Sbjct: 1052 KLEGDSTD---LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE 1108 Query: 1396 KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDK 1455 L ++ E +E+ E+ + EK K+ L E+E L +LE + + A + + ++ Sbjct: 1109 -LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167 Query: 1456 VLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISD 1515 + K+ L+E EA +E R K A EE+ +QLE +R NL++ Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAEQLEQTKRVKANLEKAKQT 1221 Query: 1516 LTEQIAETGKNLQ-------EAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568 L + E ++ ++E +K VE + +LQV E E K+ ++Q+E Sbjct: 1222 LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281 Query: 1569 LSQVK---SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD 1625 L V S+ D K + ++ L+ Q E LQ E R + K++E + Sbjct: 1282 LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE----ENRQKLSLSTKLKQVEDE 1337 Query: 1626 LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685 N QL +K + T+ Q+ D + ++D++ E +E +++ L Sbjct: 1338 KNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL 1397 Query: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745 + EE A ++ E+T+ +QEL D + +L +KK + +A+ + Sbjct: 1398 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTIS 1457 Query: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1805 +E AE +A++ T A +A L++ + A LER+ K ++DL D+ Sbjct: 1458 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 1517 Query: 1806 QLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNI 1865 K + +LE R LE +++ E K E L E QA ED K Sbjct: 1518 --------KSVHELEKSKRALEQQVE-EMKTQLEEL-----------EDELQATEDAK-- 1555 Query: 1866 LRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSR-CRRVQHELEEAAERADIAESQVNKL 1924 LRL+ + ++A+ + + +E E+ QL R R ++ ELE+ ++ +A + KL Sbjct: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKL 1615 Query: 1925 RAKSRDV 1931 +D+ Sbjct: 1616 EMDLKDL 1622 Score = 157 bits (398), Expect = 7e-38 Identities = 145/648 (22%), Positives = 298/648 (45%), Gaps = 55/648 (8%) Query: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE---- 900 KS++ K+ + ++ + T+E L ++ L K+ + EKN + Q++ E E Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354 Query: 901 ----------NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDK 950 + D +++ E + E ++L + LE + + E VA LE Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414 Query: 951 CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQT 1010 + L++++DDL + L + E K K +++ A E+ IS E++ EA + Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKF-DQLLAEEKTISAKYAEERDRAEAEARE 1473 Query: 1011 LDD--------LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062 + L+ ++ L ++N + + +DL S + K +LE++KR LE Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533 Query: 1063 LKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKID-DEQVHSLQFQKKIKELQARIEE 1121 ++ + + +LE++ Q E+ + E L ++A+ + D Q Q ++K K+L ++ E Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593 Query: 1122 LEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRD 1181 +E E+E E R+ R L +L+++ ++ A+ I+ +K +A+ + R+ Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653 Query: 1182 LEEATLQHEATAATLR------KKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDM 1235 L++ E A + K + +L E++ +R K++ ++E+ EL EI + Sbjct: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713 Query: 1236 ASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQ------NG 1289 + + K +E +E++ E ++ T+LI+D ++KA LQ N Sbjct: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQIDQINTDLNL 1768 Query: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349 E SH ++ E+ QL + + L +L+E++ ++ + KA AL++ + + Sbjct: 1769 ERSH-AQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT---ALEAKIAQLEEQLD 1824 Query: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQEAEE 1406 +E++A + R K +V +A Q ++ ++A K+L ++L+EAEE Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884 Query: 1407 NTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFD 1454 + AN+ ++++LQ E+ED + + ++L K R D Sbjct: 1885 EAQRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925 Score = 152 bits (385), Expect = 2e-36 Identities = 160/706 (22%), Positives = 316/706 (44%), Gaps = 38/706 (5%) Query: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309 E + E Q + E +T L L +K +LQ Q + E E L ++LT K Sbjct: 852 EELVKVREKQLAAENRLTEMET-LQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKK 910 Query: 1310 QALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKAN 1369 Q L + +L+ ++EEE + + + + + L EQ EEE+ A+ +LQ L K Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ--LEKVT 968 Query: 1370 SEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGE 1428 +E + + E ++ +L + KK L R+ E N K SL K K + + Sbjct: 969 TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM 1028 Query: 1429 VEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKM 1488 + DL L R L+K +R + + ++ E QA++ + + EL Sbjct: 1029 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 1088 Query: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548 EE Q ++ + L+ +IS+L E + + +AEK K+ + +E L+ L Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148 Query: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAE 1608 E+ S ++ + + E++ +K L+ + + +I+++++ +A E L L+ Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208 Query: 1609 IRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSN 1668 R + + + K+ +E + E+ ++ + +++ + V+ QL++ Q+ ++ R Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVR 1268 Query: 1669 EDLKEQLAIVERRNGLLLEELEEMKVALEQTE-RTRRLS------EQELLDASDRVQLLH 1721 +L +++ ++ EL+ + L Q++ ++ +L+ E +L D + +Q + Sbjct: 1269 TELADKVTKLQ-------VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321 Query: 1722 SQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1781 Q SL K++E + + ++E + N E K+ T A +A+ KK +D+ Sbjct: 1322 RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE---KQIATLHAQVADMKKKMEDSVG 1378 Query: 1782 HLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGA 1838 LE +K+ L++ ++ L R +E + A +K +L+ + +L +LD +++ Sbjct: 1379 CLETAEEVKRKLQKDLEGLSQRHEE-KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 1437 Query: 1839 EALKGAHKY-----ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQA 1893 K K+ E K Y E D R + + + K S R EEA EQ Sbjct: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERD-----RAEAEAREKETKALSLARALEEAMEQ- 1491 Query: 1894 NTQLSRC-RRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 +L R ++ + E+E+ D V++L KS+ Q++EE Sbjct: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELE-KSKRALEQQVEE 1536 Score = 119 bits (297), Expect = 4e-26 Identities = 118/557 (21%), Positives = 249/557 (44%), Gaps = 27/557 (4%) Query: 1393 AKKKLAQRLQEAEENTETANSKCASLEKTKQ----RLQGEVEDLMRDLERSHTACATLDK 1448 A+K A+R Q+ + CA+ K + RL +V+ L++ + A ++ Sbjct: 795 ARKAFAKRQQQLTA-MKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEE 853 Query: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKN 1508 + +K LA + E+E Q + + +L + A E+ + E LR Sbjct: 854 LVKVREKQLAA-----ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTA 908 Query: 1509 LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568 ++E+ ++ + ++E E+ + ++ EK +Q ++E+E LE EES R +L+ Sbjct: 909 KKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA--RQKLQ 963 Query: 1569 LSQVKSELDRKVIEKDEEI---------EQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619 L +V +E K +E+++ I ++ K R AE ++ + E +S++ A +LK Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA-KLK 1022 Query: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679 K E + ++E +L +Q E +K R ++G D + + +LK QLA E Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082 Query: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739 L +EE + R E ++ + + ++ + K+ L ++ Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142 Query: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT-SAHLERMKKNLEQTVKDLQ 1798 + E+E+++ + +E K + ++ + L++E T A ++ M++ Q V++L Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELA 1202 Query: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858 +L++ +++ K + Q LEN EL NE+ V + ++ K E +++E+ + Sbjct: 1203 EQLEQTKRVKANLEKAK-QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF 1261 Query: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918 E + L D V KLQ ++ + +++ +++ ++ +L++ E Sbjct: 1262 NEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321 Query: 1919 SQVNKLRAKSRDVGSQK 1935 Q L K + V +K Sbjct: 1322 RQKLSLSTKLKQVEDEK 1338 Score = 115 bits (289), Expect = 3e-25 Identities = 122/589 (20%), Positives = 261/589 (44%), Gaps = 66/589 (11%) Query: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMR 1434 WR + + + EE + L + E A ++ +E + +L E L Sbjct: 828 WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887 Query: 1435 DLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEE 1494 L+ CA ++ + L KQ+L+E +LEA EE Sbjct: 888 QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEAR-----------------VEE 926 Query: 1495 VVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA-LEEVEG 1553 ++ + L+ E K +Q+ I +L EQ+ E +E+ + K +E+ ++ ++ LEE + Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEE-----EESARQKLQLEKVTTEAKLKKLEEEQI 981 Query: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEE---IEQLKRNSQRAAEALQSVLDAEIR 1610 LE + K+ + + L +E + E++E+ + +LK + L+ L E + Sbjct: 982 ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEK 1041 Query: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670 R + + ++K+EGD ++ Q+ Q+AE + L + +L+ + +++ Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101 Query: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQEL----------LDASDRVQLL 1720 +++ +E + L E+LE + + + E+ +R +EL LD++ Q L Sbjct: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161 Query: 1721 HSQNTSLINT-KKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT 1779 S+ +N KK LE + +A+++ Q+ A E+ +AE+L++ + Sbjct: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE----------LAEQLEQTKRV 1211 Query: 1780 SAHLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLENRVRELENELDVEQKR 1836 A+LE+ K+ LE +L + + ++ L+G + + +K+E +++EL+ + + ++ Sbjct: 1212 KANLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267 Query: 1837 GAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQ 1896 E K + ++ +T + +L L+++++ + +E Q + Sbjct: 1268 RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSL 1327 Query: 1897 LSRCRRVQHE-------LEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 ++ ++V+ E LEE E E Q+ L A+ D+ +KME+ Sbjct: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM-KKKMED 1375 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 1262 bits (3265), Expect = 0.0 Identities = 713/1882 (37%), Positives = 1119/1882 (59%), Gaps = 42/1882 (2%) Query: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127 R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N Sbjct: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146 Query: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187 PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT Sbjct: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206 Query: 188 NTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFG 247 NTK+VIQY A +A + +KE PG + G LE Q++QANP+LEAFGNAKTV+NDNSSRFG Sbjct: 207 NTKKVIQYLAHVASSPKGRKE--PG-VPGELERQLLQANPILEAFGNAKTVKNDNSSRFG 263 Query: 248 KFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLIS 306 KFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L DLLL Sbjct: 264 KFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEP 323 Query: 307 TNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362 + + F P S G+ + E T ++ +LGFS EE + + ++ AV+ +G Sbjct: 324 CSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFG 376 Query: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422 N+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q +Q Sbjct: 377 NIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQA 436 Query: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCI 480 ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS EQLCI Sbjct: 437 DFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCI 495 Query: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILE 537 N+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+ ++L+ Sbjct: 496 NYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLD 555 Query: 538 EECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLD 597 EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY WL Sbjct: 556 EECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLM 612 Query: 598 KNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----ETGDSGGSKKGGKKKGSSFQTVSA 653 KN DPLN+ V L +S+ +L + ++ + G + G GG+ + F+TV Sbjct: 613 KNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQ 672 Query: 654 VFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGF 713 +++E+L++LM L +T+P FVRC++PN K G ++ LV+ QLRCNGVLEGIRICR+GF Sbjct: 673 LYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGF 732 Query: 714 PSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGL 773 P+RIL+ +F+QRY IL +AIP+G F+D K A EK++ ++++D +R G +K+FF+AG+ Sbjct: 733 PNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGV 791 Query: 774 LGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPW 833 L LEE RD K+ ++ S QA RGYL R F+K +++ ++ +Q N +++ ++HW W Sbjct: 792 LAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW 851 Query: 834 MNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQL 893 LF K+KPLL+ ++ + ++ ++ +E +S EL+ ++ L +E+ L Sbjct: 852 WRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAE 911 Query: 894 QVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSS 953 Q+++E E +AEE L K LE V EL R+ EEEE + ++ +K+ L+ Sbjct: 912 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE 971 Query: 954 LKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013 L+ ++ E K++ EK TE K+K E++ LE+ SKL+KE+K L++ + Sbjct: 972 LEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQ 1031 Query: 1014 LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDL 1073 EE+KV L K+ K E D+E L +E+K R +LE+ KR+L+G+ QE +++ Sbjct: 1032 AAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQ 1091 Query: 1074 ENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLR 1133 + +++ +L +KE EL A+ +DE Q K ++E QA + E +E++E+E R Sbjct: 1092 QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVAR 1151 Query: 1134 AKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1193 K EKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T HEA Sbjct: 1152 TKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAV 1211 Query: 1194 ATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253 LR++ ++ EL EQ++ +R K EK + L+ E+ ++ + + +L ++ E+ Sbjct: 1212 QELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRR 1271 Query: 1254 RTVEDQFSEI--KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQA 1311 R +E Q E+ +A D ++ + +Q+A+ + +N +S + E ES +L+K + Sbjct: 1272 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELEN--VSGALNEAESKTIRLSKELSS 1329 Query: 1312 LTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSE 1371 QL + + ++EET+AK A+ +++ + LREQ EEE A+ R L A ++ Sbjct: 1330 TEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQ 1389 Query: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQR----LQEAEENTETANSKCASLEKTKQRLQG 1427 +++WR + E +A E EEA+++ A+ Q E TET + LE+ ++RLQ Sbjct: 1390 LSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVD----RLERGRRRLQQ 1444 Query: 1428 EVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFK 1487 E++D DLE+ +TL+KKQR FD++LAE K + + E E A+ E R Sbjct: 1445 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1504 Query: 1488 MRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA 1547 + A EE + E L R+N+ L+ E+ L + GK++ E E+ ++ EQ +DL+ Sbjct: 1505 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1564 Query: 1548 LEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDA 1607 + E+E L E LR+++ + +K++ +R + +DE E+ +R + + D Sbjct: 1565 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1624 Query: 1608 EIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRS 1667 E + R A+ +KK+EG+L E++ Q+ + + E K LR +Q Q+K+ +++ S Sbjct: 1625 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1684 Query: 1668 NEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSL 1727 E++ Q E+R L E+ ++ L ++R RR ++Q+ + +D V + ++ Sbjct: 1685 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1744 Query: 1728 INTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787 + K++LE + Q + E+E S ++ +K + + EL E+ SA E + Sbjct: 1745 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1804 Query: 1788 KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKY 1847 + LE+ +++L+ RL E + A K I LE+++ + E +L+ E + + K + Sbjct: 1805 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1864 Query: 1848 ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL 1907 E+++KE+ Q EE+ + +L+D ++K +VK KRQ EEAEE+A+ + RR+Q EL Sbjct: 1865 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1924 Query: 1908 EEAAERADIAESQVNKLRAKSR 1929 E+ E A+ +V LR + R Sbjct: 1925 EDVTESAESMNREVTTLRNRLR 1946 Score = 214 bits (546), Expect = 5e-55 Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%) Query: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894 K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q Sbjct: 1044 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101 Query: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947 + + E L A R E L+KS +A + E E LE E ++ ++R+L Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161 Query: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007 ++ +L+ +++D TL ++ + + ++E LEE + L++ H Sbjct: 1162 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1218 Query: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063 Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L Sbjct: 1219 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1278 Query: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123 + Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + + Sbjct: 1279 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1338 Query: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183 E ++ E + + + + E + E+LEE + A + +A+ + RR E Sbjct: 1339 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1398 Query: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237 E EA R+ ++ +AE E +D L+R +++L++E + M+++ Sbjct: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1458 Query: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297 + L K + ++ E++ + ++A +E++ + L L+ +EE Sbjct: 1459 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1511 Query: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357 ++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++ Sbjct: 1512 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1571 Query: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417 + A + V +T++E D R E EE +++LA++L++AE + + Sbjct: 1572 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1631 Query: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477 +++L+GE+E+L + + K+ R + E ++++E++ E + Sbjct: 1632 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1691 Query: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537 +R L + + ++L R + Q++ ++ +++A + + K+ + Sbjct: 1692 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1751 Query: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594 E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R Sbjct: 1752 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1811 Query: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654 Q L DA R+R+ +E L + E QL R+ + K +R + +L Sbjct: 1812 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1868 Query: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714 K+ L +++ R + L++QL R L +LEE + + + RR ++EL D + Sbjct: 1869 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1928 Query: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762 + + ++ + T+L N ++ ++E ++E+A++A Sbjct: 1929 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 Score = 133 bits (334), Expect = 2e-30 Identities = 178/808 (22%), Positives = 345/808 (42%), Gaps = 89/808 (11%) Query: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212 +LEE I ++ + A RR ++ Q A LR Q + A L + Sbjct: 794 QLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA----LRVMQRNCAAYLKLRHW 849 Query: 1213 NLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272 R+ K+ K ++ + + + + + L K + +++ R V + + +E++ + Sbjct: 850 QWWRLFTKV-KPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 908 Query: 1273 LIHDLNMQK---ARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKA 1329 L L + A + G L+ R +E E ++S+L +A + EE RQM+ T+ Sbjct: 909 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL----EARVGEEEECSRQMQ--TEK 962 Query: 1330 KNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAI---QR 1386 K H + H E E+ A+ +LQ L K +E K+E D + + Sbjct: 963 KRLQQHIQELEAH--------LEAEEGARQKLQ--LEKVTTEAKM--KKFEEDLLLLEDQ 1010 Query: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446 +L + +K L RL E K SL K + + + + D+ L + L Sbjct: 1011 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1070 Query: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQ----KESRSLSTELFKMRNAYEEVVDQLETL 1502 +K +R D +E ++++ E Q E + ++ L L + + L++L Sbjct: 1071 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1130 Query: 1503 RRENKNLQEEISDL-TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561 R L E DL +E++A T +AEK ++ + +E L+ LE+ S ++ Sbjct: 1131 REAQAALAEAQEDLESERVART-----KAEKQRRDLGEELEALRGELEDTLDSTNAQQEL 1185 Query: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621 + + E++++K L+ + + +++L++ +A L L+ R + + + Sbjct: 1186 RSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLA 1245 Query: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681 +E +++E+ +L E ++ R ++ QL++ Q D R+ + E+L + Sbjct: 1246 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA- 1304 Query: 1682 NGLLLEELEEMKVALEQTE-RTRRLS------EQELLDASDRVQLLHSQNTSLINTKKKL 1734 ELE + AL + E +T RLS E +L DA + +Q +L + + + Sbjct: 1305 ------ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 1358 Query: 1735 EADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1794 EA+ A + ++E +E+ E ++ T A ++E +++++ + LE ++ + Sbjct: 1359 EAEAAGLREQLE---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1415 Query: 1795 KDLQHRLDEAEQLALKGGKKQ--IQKLENRVRELENELD-----VEQKRGAEALKGAHKY 1847 + EAE L + +K + +LE R L+ ELD +EQ+R + + K Sbjct: 1416 R-------EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQR--QLVSTLEKK 1466 Query: 1848 ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL 1907 +RK ++ AEE +A V + E AE + + +R + L Sbjct: 1467 QRKFDQLL--AEE---------------KAAVLRAVEERERAEAEGREREARALSLTRAL 1509 Query: 1908 EEAAERADIAESQVNKLRAKSRDVGSQK 1935 EE E + E Q LRA+ + S K Sbjct: 1510 EEEQEAREELERQNRALRAELEALLSSK 1537 Score = 116 bits (291), Expect = 2e-25 Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%) Query: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351 R+ K + Q+T+ + L + +EL++ E + QS+R +L Q Sbjct: 853 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 902 Query: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411 EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE + Sbjct: 903 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 956 Query: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 ++ K+RLQ +++L LE A +++ +KV E K K E L Sbjct: 957 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1006 Query: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526 Q KE + L L + + E +++++L + + I+D+ +++ + K Sbjct: 1007 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1066 Query: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586 QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + + Sbjct: 1067 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1126 Query: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643 ++ L+ AEA L+S A ++ L +++E E+E L +N Q Sbjct: 1127 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186 Query: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700 K + V +LK + L++ R +E ++L +R G L E+LE+ + E Sbjct: 1187 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1240 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 +TR E E+ + + L + +++LE + + Q + + A EK + Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 +A + ++ L + + + L + + E + D Q L E + L G + ++ +E Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1359 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 L +L+ E A + + ++ E + EE+ + ++ + + + Sbjct: 1360 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1419 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 + ++ E E + RR+Q EL++A + V+ L K R EE Sbjct: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 1258 bits (3255), Expect = 0.0 Identities = 712/1887 (37%), Positives = 1118/1887 (59%), Gaps = 44/1887 (2%) Query: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127 R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N Sbjct: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146 Query: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187 PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT Sbjct: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206 Query: 188 NTKRVIQYFATIAVTGDKKKETQ-PGKMQ----GTLEDQIIQANPLLEAFGNAKTVRNDN 242 NTK+VIQY A +A + +KE P + G LE Q++QANP+LEAFGNAKTV+NDN Sbjct: 207 NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266 Query: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-ID 301 SSRFGKFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L D Sbjct: 267 SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326 Query: 302 LLLISTNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGA 357 LLL + + F P S G+ + E T ++ +LGFS EE + + ++ A Sbjct: 327 LLLEPCSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSA 379 Query: 358 VMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQ 417 V+ +GN+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q Sbjct: 380 VLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQ 439 Query: 418 NVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSL 475 +Q ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS Sbjct: 440 TKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSF 498 Query: 476 EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GI 532 EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+ Sbjct: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGL 558 Query: 533 FSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNI 592 ++L+EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY Sbjct: 559 LALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKA 615 Query: 593 AGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----ETGDSGGSKKGGKKKGSSF 648 WL KN DPLN+ V L +S+ +L + ++ + G + G GG+ + F Sbjct: 616 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMF 675 Query: 649 QTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRI 708 +TV +++E+L++LM L +T+P FVRC++PN K G ++ LV+ QLRCNGVLEGIRI Sbjct: 676 RTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRI 735 Query: 709 CRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVF 768 CR+GFP+RIL+ +F+QRY IL +AIP+G F+D K A EK++ ++++D +R G +K+F Sbjct: 736 CRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIF 794 Query: 769 FKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNV 828 F+AG+L LEE RD K+ ++ S QA RGYL R F+K +++ ++ +Q N +++ + Sbjct: 795 FRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKL 854 Query: 829 KHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEK 888 +HW W LF K+KPLL+ ++ + ++ ++ +E +S EL+ ++ L +E+ Sbjct: 855 RHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEER 914 Query: 889 NDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLE 948 L Q+++E E +AEE L K LE V EL R+ EEEE + ++ +K+ L+ Sbjct: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974 Query: 949 DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQ 1008 L+ ++ E K++ EK TE K+K E++ LE+ SKL+KE+K L++ Sbjct: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1034 Query: 1009 QTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQE 1068 + EE+KV L K+ K E D+E L +E+K R +LE+ KR+L+G+ QE Sbjct: 1035 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQE 1094 Query: 1069 SIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEA 1128 +++ + +++ +L +KE EL A+ +DE Q K ++E QA + E +E++E+ Sbjct: 1095 QMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLES 1154 Query: 1129 EHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188 E R K EKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T Sbjct: 1155 ERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214 Query: 1189 HEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSN 1248 HEA LR++ ++ EL EQ++ +R K EK + L+ E+ ++ + + +L ++ Sbjct: 1215 HEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQE 1274 Query: 1249 IERTCRTVEDQFSEI--KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLT 1306 E+ R +E Q E+ +A D ++ + +Q+A+ + +N +S + E ES +L+ Sbjct: 1275 GEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELEN--VSGALNEAESKTIRLS 1332 Query: 1307 KSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALS 1366 K + QL + + ++EET+AK A+ +++ + LREQ EEE A+ R L Sbjct: 1333 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1392 Query: 1367 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR----LQEAEENTETANSKCASLEKTK 1422 A +++++WR + E +A E EEA+++ A+ Q E TET + LE+ + Sbjct: 1393 TAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVD----RLERGR 1447 Query: 1423 QRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLS 1482 +RLQ E++D DLE+ +TL+KKQR FD++LAE K + + E E A+ E R Sbjct: 1448 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1507 Query: 1483 TELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKS 1542 + A EE + E L R+N+ L+ E+ L + GK++ E E+ ++ EQ + Sbjct: 1508 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1567 Query: 1543 DLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQ 1602 DL+ + E+E L E LR+++ + +K++ +R + +DE E+ +R + + Sbjct: 1568 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1627 Query: 1603 SVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLD 1662 D E + R A+ +KK+EG+L E++ Q+ + + E K LR +Q Q+K+ ++ Sbjct: 1628 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1687 Query: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722 + S E++ Q E+R L E+ ++ L ++R RR ++Q+ + +D V + Sbjct: 1688 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1747 Query: 1723 QNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782 +++ K++LE + Q + E+E S ++ +K + + EL E+ SA Sbjct: 1748 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1807 Query: 1783 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALK 1842 E ++ LE+ +++L+ RL E + A K I LE+++ + E +L+ E + + K Sbjct: 1808 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 1867 Query: 1843 GAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRR 1902 + E+++KE+ Q EE+ + +L+D ++K +VK KRQ EEAEE+A+ + RR Sbjct: 1868 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1927 Query: 1903 VQHELEEAAERADIAESQVNKLRAKSR 1929 +Q ELE+ E A+ +V LR + R Sbjct: 1928 LQRELEDVTESAESMNREVTTLRNRLR 1954 Score = 214 bits (546), Expect = 5e-55 Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%) Query: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894 K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q Sbjct: 1052 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109 Query: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947 + + E L A R E L+KS +A + E E LE E ++ ++R+L Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169 Query: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007 ++ +L+ +++D TL ++ + + ++E LEE + L++ H Sbjct: 1170 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1226 Query: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063 Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L Sbjct: 1227 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1286 Query: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123 + Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + + Sbjct: 1287 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1346 Query: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183 E ++ E + + + + E + E+LEE + A + +A+ + RR E Sbjct: 1347 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1406 Query: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237 E EA R+ ++ +AE E +D L+R +++L++E + M+++ Sbjct: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1466 Query: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297 + L K + ++ E++ + ++A +E++ + L L+ +EE Sbjct: 1467 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1519 Query: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357 ++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++ Sbjct: 1520 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1579 Query: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417 + A + V +T++E D R E EE +++LA++L++AE + + Sbjct: 1580 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1639 Query: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477 +++L+GE+E+L + + K+ R + E ++++E++ E + Sbjct: 1640 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1699 Query: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537 +R L + + ++L R + Q++ ++ +++A + + K+ + Sbjct: 1700 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1759 Query: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594 E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R Sbjct: 1760 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1819 Query: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654 Q L DA R+R+ +E L + E QL R+ + K +R + +L Sbjct: 1820 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1876 Query: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714 K+ L +++ R + L++QL R L +LEE + + + RR ++EL D + Sbjct: 1877 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1936 Query: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762 + + ++ + T+L N ++ ++E ++E+A++A Sbjct: 1937 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984 Score = 133 bits (334), Expect = 2e-30 Identities = 178/808 (22%), Positives = 345/808 (42%), Gaps = 89/808 (11%) Query: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212 +LEE I ++ + A RR ++ Q A LR Q + A L + Sbjct: 802 QLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA----LRVMQRNCAAYLKLRHW 857 Query: 1213 NLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272 R+ K+ K ++ + + + + + L K + +++ R V + + +E++ + Sbjct: 858 QWWRLFTKV-KPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 916 Query: 1273 LIHDLNMQK---ARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKA 1329 L L + A + G L+ R +E E ++S+L +A + EE RQM+ T+ Sbjct: 917 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL----EARVGEEEECSRQMQ--TEK 970 Query: 1330 KNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAI---QR 1386 K H + H E E+ A+ +LQ L K +E K+E D + + Sbjct: 971 KRLQQHIQELEAH--------LEAEEGARQKLQ--LEKVTTEAKM--KKFEEDLLLLEDQ 1018 Query: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446 +L + +K L RL E K SL K + + + + D+ L + L Sbjct: 1019 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078 Query: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQ----KESRSLSTELFKMRNAYEEVVDQLETL 1502 +K +R D +E ++++ E Q E + ++ L L + + L++L Sbjct: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1138 Query: 1503 RRENKNLQEEISDL-TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561 R L E DL +E++A T +AEK ++ + +E L+ LE+ S ++ Sbjct: 1139 REAQAALAEAQEDLESERVART-----KAEKQRRDLGEELEALRGELEDTLDSTNAQQEL 1193 Query: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621 + + E++++K L+ + + +++L++ +A L L+ R + + + Sbjct: 1194 RSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLA 1253 Query: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681 +E +++E+ +L E ++ R ++ QL++ Q D R+ + E+L + Sbjct: 1254 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA- 1312 Query: 1682 NGLLLEELEEMKVALEQTE-RTRRLS------EQELLDASDRVQLLHSQNTSLINTKKKL 1734 ELE + AL + E +T RLS E +L DA + +Q +L + + + Sbjct: 1313 ------ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 1366 Query: 1735 EADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1794 EA+ A + ++E +E+ E ++ T A ++E +++++ + LE ++ + Sbjct: 1367 EAEAAGLREQLE---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423 Query: 1795 KDLQHRLDEAEQLALKGGKKQ--IQKLENRVRELENELD-----VEQKRGAEALKGAHKY 1847 + EAE L + +K + +LE R L+ ELD +EQ+R + + K Sbjct: 1424 R-------EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQR--QLVSTLEKK 1474 Query: 1848 ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL 1907 +RK ++ AEE +A V + E AE + + +R + L Sbjct: 1475 QRKFDQLL--AEE---------------KAAVLRAVEERERAEAEGREREARALSLTRAL 1517 Query: 1908 EEAAERADIAESQVNKLRAKSRDVGSQK 1935 EE E + E Q LRA+ + S K Sbjct: 1518 EEEQEAREELERQNRALRAELEALLSSK 1545 Score = 116 bits (291), Expect = 2e-25 Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%) Query: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351 R+ K + Q+T+ + L + +EL++ E + QS+R +L Q Sbjct: 861 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 910 Query: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411 EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE + Sbjct: 911 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 964 Query: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 ++ K+RLQ +++L LE A +++ +KV E K K E L Sbjct: 965 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1014 Query: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526 Q KE + L L + + E +++++L + + I+D+ +++ + K Sbjct: 1015 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1074 Query: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586 QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + + Sbjct: 1075 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1134 Query: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643 ++ L+ AEA L+S A ++ L +++E E+E L +N Q Sbjct: 1135 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1194 Query: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700 K + V +LK + L++ R +E ++L +R G L E+LE+ + E Sbjct: 1195 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1248 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 +TR E E+ + + L + +++LE + + Q + + A EK + Sbjct: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 +A + ++ L + + + L + + E + D Q L E + L G + ++ +E Sbjct: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1367 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 L +L+ E A + + ++ E + EE+ + ++ + + + Sbjct: 1368 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1427 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 + ++ E E + RR+Q EL++A + V+ L K R EE Sbjct: 1428 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1485 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 1245 bits (3221), Expect = 0.0 Identities = 712/1920 (37%), Positives = 1118/1920 (58%), Gaps = 77/1920 (4%) Query: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127 R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N Sbjct: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146 Query: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187 PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT Sbjct: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206 Query: 188 NTKRVIQYFATIAVTGDKKKETQ-PGKMQ----GTLEDQIIQANPLLEAFGNAKTVRNDN 242 NTK+VIQY A +A + +KE P + G LE Q++QANP+LEAFGNAKTV+NDN Sbjct: 207 NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266 Query: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-ID 301 SSRFGKFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L D Sbjct: 267 SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326 Query: 302 LLLISTNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGA 357 LLL + + F P S G+ + E T ++ +LGFS EE + + ++ A Sbjct: 327 LLLEPCSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSA 379 Query: 358 VMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQ 417 V+ +GN+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q Sbjct: 380 VLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQ 439 Query: 418 NVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSL 475 +Q ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS Sbjct: 440 TKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSF 498 Query: 476 EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GI 532 EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+ Sbjct: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGL 558 Query: 533 FSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNI 592 ++L+EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY Sbjct: 559 LALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKA 615 Query: 593 AGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----------------------- 629 WL KN DPLN+ V L +S+ +L + ++ + G Sbjct: 616 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSS 675 Query: 630 --------------ETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVR 675 + G GG+ + F+TV +++E+L++LM L +T+P FVR Sbjct: 676 AISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 735 Query: 676 CLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIP 735 C++PN K G ++ LV+ QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY IL +AIP Sbjct: 736 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 795 Query: 736 EGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAV 795 +G F+D K A EK++ ++++D +R G +K+FF+AG+L LEE RD K+ ++ S QA Sbjct: 796 KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 854 Query: 796 CRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMAT 855 RGYL R F+K +++ ++ +Q N +++ ++HW W LF K+KPLL+ ++ + Sbjct: 855 ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 914 Query: 856 MKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKS 915 ++ ++ +E +S EL+ ++ L +E+ L Q+++E E +AEE L Sbjct: 915 RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 974 Query: 916 KILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHAT 975 K LE V EL R+ EEEE + ++ +K+ L+ L+ ++ E K++ EK T Sbjct: 975 KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 1034 Query: 976 ENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQT 1035 E K+K E++ LE+ SKL+KE+K L++ + EE+KV L K+ K E Sbjct: 1035 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1094 Query: 1036 DDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQ 1095 D+E L +E+K R +LE+ KR+L+G+ QE +++ + +++ +L +KE EL Sbjct: 1095 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1154 Query: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155 A+ +DE Q K ++E QA + E +E++E+E R K EKQR DL ELE + LE Sbjct: 1155 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1214 Query: 1156 EASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQ 1215 + +T+AQ E+ KRE E ++++ LEE T HEA LR++ ++ EL EQ++ + Sbjct: 1215 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1274 Query: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI--KAKDEQQTQL 1273 R K EK + L+ E+ ++ + + +L ++ E+ R +E Q E+ +A D ++ + Sbjct: 1275 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1334 Query: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333 +Q+A+ + +N +S + E ES +L+K + QL + + ++EET+AK A+ Sbjct: 1335 EAAEKLQRAQAELEN--VSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1392 Query: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393 +++ + LREQ EEE A+ R L A +++++WR + E +A E EEA Sbjct: 1393 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEA 1451 Query: 1394 KKKLAQR----LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKK 1449 +++ A+ Q E TET + LE+ ++RLQ E++D DLE+ +TL+KK Sbjct: 1452 RRRAAREAEALTQRLAEKTETVD----RLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1507 Query: 1450 QRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNL 1509 QR FD++LAE K + + E E A+ E R + A EE + E L R+N+ L Sbjct: 1508 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1567 Query: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569 + E+ L + GK++ E E+ ++ EQ +DL+ + E+E L E LR+++ + Sbjct: 1568 RAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV 1627 Query: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEM 1629 +K++ +R + +DE E+ +R + + D E + R A+ +KK+EG+L E+ Sbjct: 1628 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEEL 1687 Query: 1630 EIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEEL 1689 + Q+ + + E K LR +Q Q+K+ +++ S E++ Q E+R L E+ Sbjct: 1688 KAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEV 1747 Query: 1690 EEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSI 1749 ++ L ++R RR ++Q+ + +D V + +++ K++LE + Q + E+E Sbjct: 1748 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807 Query: 1750 QESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809 S ++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A Sbjct: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867 Query: 1810 KGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQ 1869 K I LE+++ + E +L+ E + + K + E+++KE+ Q EE+ + +L+ Sbjct: 1868 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLR 1927 Query: 1870 DLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929 D ++K +VK KRQ EEAEE+A+ + RR+Q ELE+ E A+ +V LR + R Sbjct: 1928 DQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987 Score = 214 bits (546), Expect = 5e-55 Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%) Query: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894 K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q Sbjct: 1085 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142 Query: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947 + + E L A R E L+KS +A + E E LE E ++ ++R+L Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202 Query: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007 ++ +L+ +++D TL ++ + + ++E LEE + L++ H Sbjct: 1203 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1259 Query: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063 Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L Sbjct: 1260 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1319 Query: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123 + Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + + Sbjct: 1320 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1379 Query: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183 E ++ E + + + + E + E+LEE + A + +A+ + RR E Sbjct: 1380 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1439 Query: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237 E EA R+ ++ +AE E +D L+R +++L++E + M+++ Sbjct: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499 Query: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297 + L K + ++ E++ + ++A +E++ + L L+ +EE Sbjct: 1500 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1552 Query: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357 ++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++ Sbjct: 1553 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1612 Query: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417 + A + V +T++E D R E EE +++LA++L++AE + + Sbjct: 1613 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1672 Query: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477 +++L+GE+E+L + + K+ R + E ++++E++ E + Sbjct: 1673 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1732 Query: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537 +R L + + ++L R + Q++ ++ +++A + + K+ + Sbjct: 1733 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1792 Query: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594 E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R Sbjct: 1793 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1852 Query: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654 Q L DA R+R+ +E L + E QL R+ + K +R + +L Sbjct: 1853 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1909 Query: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714 K+ L +++ R + L++QL R L +LEE + + + RR ++EL D + Sbjct: 1910 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1969 Query: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762 + + ++ + T+L N ++ ++E ++E+A++A Sbjct: 1970 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017 Score = 133 bits (334), Expect = 2e-30 Identities = 178/808 (22%), Positives = 345/808 (42%), Gaps = 89/808 (11%) Query: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212 +LEE I ++ + A RR ++ Q A LR Q + A L + Sbjct: 835 QLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA----LRVMQRNCAAYLKLRHW 890 Query: 1213 NLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272 R+ K+ K ++ + + + + + L K + +++ R V + + +E++ + Sbjct: 891 QWWRLFTKV-KPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 949 Query: 1273 LIHDLNMQK---ARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKA 1329 L L + A + G L+ R +E E ++S+L +A + EE RQM+ T+ Sbjct: 950 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSEL----EARVGEEEECSRQMQ--TEK 1003 Query: 1330 KNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAI---QR 1386 K H + H E E+ A+ +LQ L K +E K+E D + + Sbjct: 1004 KRLQQHIQELEAH--------LEAEEGARQKLQ--LEKVTTEAKM--KKFEEDLLLLEDQ 1051 Query: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446 +L + +K L RL E K SL K + + + + D+ L + L Sbjct: 1052 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1111 Query: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQ----KESRSLSTELFKMRNAYEEVVDQLETL 1502 +K +R D +E ++++ E Q E + ++ L L + + L++L Sbjct: 1112 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1171 Query: 1503 RRENKNLQEEISDL-TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561 R L E DL +E++A T +AEK ++ + +E L+ LE+ S ++ Sbjct: 1172 REAQAALAEAQEDLESERVART-----KAEKQRRDLGEELEALRGELEDTLDSTNAQQEL 1226 Query: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621 + + E++++K L+ + + +++L++ +A L L+ R + + + Sbjct: 1227 RSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLA 1286 Query: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681 +E +++E+ +L E ++ R ++ QL++ Q D R+ + E+L + Sbjct: 1287 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA- 1345 Query: 1682 NGLLLEELEEMKVALEQTE-RTRRLS------EQELLDASDRVQLLHSQNTSLINTKKKL 1734 ELE + AL + E +T RLS E +L DA + +Q +L + + + Sbjct: 1346 ------ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 1399 Query: 1735 EADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1794 EA+ A + ++E +E+ E ++ T A ++E +++++ + LE ++ + Sbjct: 1400 EAEAAGLREQLE---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1456 Query: 1795 KDLQHRLDEAEQLALKGGKKQ--IQKLENRVRELENELD-----VEQKRGAEALKGAHKY 1847 + EAE L + +K + +LE R L+ ELD +EQ+R + + K Sbjct: 1457 R-------EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQR--QLVSTLEKK 1507 Query: 1848 ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL 1907 +RK ++ AEE +A V + E AE + + +R + L Sbjct: 1508 QRKFDQLL--AEE---------------KAAVLRAVEERERAEAEGREREARALSLTRAL 1550 Query: 1908 EEAAERADIAESQVNKLRAKSRDVGSQK 1935 EE E + E Q LRA+ + S K Sbjct: 1551 EEEQEAREELERQNRALRAELEALLSSK 1578 Score = 116 bits (291), Expect = 2e-25 Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%) Query: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351 R+ K + Q+T+ + L + +EL++ E + QS+R +L Q Sbjct: 894 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 943 Query: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411 EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE + Sbjct: 944 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 997 Query: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 ++ K+RLQ +++L LE A +++ +KV E K K E L Sbjct: 998 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1047 Query: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526 Q KE + L L + + E +++++L + + I+D+ +++ + K Sbjct: 1048 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1107 Query: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586 QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + + Sbjct: 1108 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1167 Query: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643 ++ L+ AEA L+S A ++ L +++E E+E L +N Q Sbjct: 1168 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227 Query: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700 K + V +LK + L++ R +E ++L +R G L E+LE+ + E Sbjct: 1228 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1281 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 +TR E E+ + + L + +++LE + + Q + + A EK + Sbjct: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 +A + ++ L + + + L + + E + D Q L E + L G + ++ +E Sbjct: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1400 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 L +L+ E A + + ++ E + EE+ + ++ + + + Sbjct: 1401 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1460 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 + ++ E E + RR+Q EL++A + V+ L K R EE Sbjct: 1461 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 608 bits (1569), Expect = e-173 Identities = 445/1462 (30%), Positives = 729/1462 (49%), Gaps = 135/1462 (9%) Query: 81 NPPKFDKIEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEV 139 NP D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y ++ Sbjct: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123 Query: 140 VAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATI 199 + AY G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+ Sbjct: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183 Query: 200 AVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 259 + + + +E++++ +NP++E+ GNAKT RNDNSSRFGK+I I F + Sbjct: 184 SGSAS----------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYR 233 Query: 260 LASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDFPFVSQG- 318 + A++ TYLLEKSRV FQ ER+YHIFYQ+ ++ K +L + N +F + QG Sbjct: 234 IIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGG 292 Query: 319 EVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPD 378 + +DD++E+ T A +LG S ++GI+++ ++H GN+ F + + P Sbjct: 293 SPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPP 352 Query: 379 GTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMF 438 E LMG++ EM LC ++ E K + Q TN+ ALAK +Y K+F Sbjct: 353 KHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLF 412 Query: 439 LWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVL 498 W+V +NQ L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F L Sbjct: 413 NWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKL 472 Query: 499 EQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQH 558 EQEEY KE I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ H Sbjct: 473 EQEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531 Query: 559 LGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKL 618 L K F+KP+ KA F + H+A V+Y G+L+KNKD + E + + + S K+ Sbjct: 532 LNKCALFEKPR-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKM 587 Query: 619 LSFLFSNYAGAETGDSGGSK---------------KGGKKKGSSFQTVSAVFRENLNKLM 663 L LF + A + S S + G+ +TV FR +L+ LM Sbjct: 588 LPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLM 647 Query: 664 TNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFK 723 L +T PH+VRC+ PN+ K P D + QLR GVLE IRI GFPSR Y +F Sbjct: 648 ETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFF 707 Query: 724 QRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDE 783 RYR+L + D K + +L + +D+++++FG TK+FF+AG + LE++R + Sbjct: 708 SRYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRAD 764 Query: 784 KLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFM---------NVKHWPWM 834 KL Q RG+L+R KK + R + +Q +R + K + Sbjct: 765 KLRAACIRIQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATII 821 Query: 835 NLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQE------- 887 ++++ + + + + + + + R LAR+ R+ E K V + + Sbjct: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLR--GFLARNRYRKILREHKAVIIQKRVRGWLAR 879 Query: 888 ---KNDL-----------QLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE 933 K + ++ + E + L E K I +E K+ +L +++E+ Sbjct: 880 THYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQ 939 Query: 934 EEMNSELVAKKRNLE----DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989 + LV K NLE + L+ D++ L+L+ E+E +V +L EE+ L Sbjct: 940 NKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKL 995 Query: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049 +++ + EKK ++E + Q E V+ L + N L+Q+ + L + Q+ K Sbjct: 996 RKDLEQTRSEKKCIEEHADRY---KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052 Query: 1050 ADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQ 1109 E ++KL + K + +DL +++ + + L E S+L+ + DD + Sbjct: 1053 T--ETMEKKLVEETKQLE---LDLNDERLRYQNLLN----EFSRLEERYDDLKEEMTLMV 1103 Query: 1110 KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMN- 1168 K R + E+E+ ++I E+E+I R EE S ++M+ Sbjct: 1104 HVPKPGHKRTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEPS-EKKVPLDMSL 1154 Query: 1169 ----KKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKE 1224 +KR E ++ ++ +++ + E + K+ + G +++ +Q+LE E Sbjct: 1155 FLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE 1214 Query: 1225 KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284 +LK E++++ +ALS+ KS E T + EQ T + +L+++K + Sbjct: 1215 NKKLKNELNELR---KALSE-KSAPEVTAPGA----PAYRVLMEQLTSVSEELDVRKEEV 1266 Query: 1285 QTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH-ALQSSRHD 1343 +L V +KE++ Q K +T L+ + + K + A A+ L+ + Sbjct: 1267 LILRSQL---VSQKEAI--QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRS 1321 Query: 1344 CDLLREQYEEEQE---AKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400 L + E+ E L++A S++ + +E +A E++ K++ ++ Sbjct: 1322 SALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQ 1381 Query: 1401 LQEAEENTETANSKC--ASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLA 1458 Q +N + ASL+ RL E DLM LE+ DK R K L Sbjct: 1382 QQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQ-------DKTVRKLKKQLK 1434 Query: 1459 EWKQKLDESQAELEAAQKESRS 1480 + +K+ ELE Q E+ S Sbjct: 1435 VFAKKI----GELEVGQMENIS 1452 Score = 85.5 bits (210), Expect = 5e-16 Identities = 134/635 (21%), Positives = 255/635 (40%), Gaps = 112/635 (17%) Query: 1084 LKKKEFELSQLQAK-IDDEQVHSLQFQKKIKELQARIEE--------LEEEIEAEHTLRA 1134 + K+E + +++A+ ++ + + + KI +LQ +++E +E+ E + Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959 Query: 1135 KIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194 + EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + + Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009 Query: 1195 TLRKKQADSVAELGEQ-IDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253 ++ AD + EQ + NL+ L++EK L I A + Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMT------------- 1053 Query: 1254 RTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313 T+E K E+ QL DLN ++ R Q E S E + L ++T L Sbjct: 1054 ETME------KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102 Query: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVA 1373 + + + + T + N + S + + + + EE E K L +L + Sbjct: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK-- 1160 Query: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLM 1433 R ELE+ K+ + L EE + +K E+ + +++G Sbjct: 1161 ------------RVTELEQEKQVMQDELDRKEEQVLRSKAK----EEERPQIRGA----- 1199 Query: 1434 RDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYE 1493 +LE L+ + + L E ++ L E A A AY Sbjct: 1200 -ELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP------------AYR 1246 Query: 1494 EVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553 +++QL ++ E +EE+ L Q+ + +Q + + +D + LE+V+ Sbjct: 1247 VLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTM-----TDSTILLEDVQK 1301 Query: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRN 1613 + E + L+ + S LD + +D E+ + ++A L+S L ++ RS Sbjct: 1302 MKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHE 1361 Query: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673 + + + G++ ++ + +NRQ QL L L R L+ Sbjct: 1362 NEA---EALRGEIQSLKEE---NNRQQ------------QLLAQNLQLPPEARIEASLQH 1403 Query: 1674 QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQ 1708 ++ + N L+E+LE +Q + R+L +Q Sbjct: 1404 EITRLTNENLDLMEQLE------KQDKTVRKLKKQ 1432 Score = 75.1 bits (183), Expect = 6e-13 Identities = 133/633 (21%), Positives = 276/633 (43%), Gaps = 91/633 (14%) Query: 1022 NGLIKINAKLEQQTDD----------LEGSLEQE-KKLRADLERAKRKLEGDLKMSQESI 1070 N ++++ K+++Q D LEG E +KLR+DLER L++S+E Sbjct: 927 NKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLER--------LQLSEEEA 978 Query: 1071 MDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEH 1130 ++E++ K +L Q +++ + H+ +++++ ++L + ++E E+ Sbjct: 979 KVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKE-------EN 1031 Query: 1131 TLRAKIEKQRSD--LARELEEISERLEEASGATSAQIEMNKKREA--------EFQKMRR 1180 TL K EK+ + + ++ +E++E +E+ + Q+E++ E EF ++ Sbjct: 1032 TL-LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090 Query: 1181 ---DL-EEATLQ-------HEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELK 1229 DL EE TL H+ T +T +++ + +I ++ + + E E SE K Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI--FSSEIAEMEDIPSRTE-EPSEKK 1147 Query: 1230 MEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNG 1289 + +D S L K + +E+ + ++D+ D ++ Q++ ++ R Q + Sbjct: 1148 VPLD--MSLFLKLQKRVTELEQEKQVMQDEL------DRKEEQVLRSKAKEEERPQIRGA 1199 Query: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349 EL + +++ L S+ K K L + + L + E A A A+ + L+ + Sbjct: 1200 ELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRV--------LMEQ 1251 Query: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK--LAQRLQEAEEN 1407 +E + L + V+Q +AIQ ++ L + +Q+ ++ Sbjct: 1252 LTSVSEELDVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTILLEDVQKMKDK 1305 Query: 1408 TETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDES 1467 E A + L++T + + +L D E L + R + L K+ + Sbjct: 1306 GEIAQAYIG-LKETNRSSALDYHELNEDGEL-WLVYEGLKQANRLLESQLQSQKRSHEN- 1362 Query: 1468 QAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNL 1527 E EA + E +SL E + + + + QL R +LQ EI+ LT + + + Sbjct: 1363 --EAEALRGEIQSLKEENNRQQQLLAQNL-QLPPEARIEASLQHEITRLTNENLDL---M 1416 Query: 1528 QEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDR--KVIEKDE 1585 ++ EK K V + K L+V +++ G LE + + + Q+ E R + K++ Sbjct: 1417 EQLEKQDKTVRKLKKQLKVFAKKI-GELEVGQME----NISPGQIIDEPIRPVNIPRKEK 1471 Query: 1586 EIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618 + + + + + L L E++ R A+ L Sbjct: 1472 DFQGMLEYKKEDEQKLVKNLILELKPRGVAVNL 1504 Score = 52.4 bits (124), Expect = 4e-06 Identities = 88/464 (18%), Positives = 205/464 (44%), Gaps = 60/464 (12%) Query: 1462 QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIA 1521 +KL +E +K + ++ +++ +E + L + NL+ + TE++ Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965 Query: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581 + LQ +E+ K+ LQ +I +++ +L Q +SE +K I Sbjct: 966 SDLERLQLSEEEAKVATGRVLSLQ--------------EEIAKLRKDLEQTRSE--KKCI 1009 Query: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMA 1641 E E ++ K+ +++ L + ++ N L+ +K+ LN +Q ++M Sbjct: 1010 E--EHADRYKQETEQ--------LVSNLKEENTLLKQEKEA---LNHRIVQ---QAKEMT 1053 Query: 1642 ETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM----KVALE 1697 ET + + + + K +L L+D ++L + + +E R L EE+ M K + Sbjct: 1054 ETME--KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111 Query: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757 +T+ T +E E + +S+ ++ + + ++KK+ D++ Sbjct: 1112 RTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL--------------- 1156 Query: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817 K +K +T+ + ++ E D K E+ ++ E E L + + + + Sbjct: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENK 1216 Query: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQA 1877 KL+N + EL L E+ GA Y ++++T +EE ++ + + L+ L++ Sbjct: 1217 KLKNELNELRKALS-EKSAPEVTAPGAPAYRVLMEQLTSVSEE--LDVRKEEVLI--LRS 1271 Query: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921 ++ S K +A + ++ NT ++ + ++++ ++ +IA++ + Sbjct: 1272 QLVSQK-EAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 608 bits (1568), Expect = e-173 Identities = 449/1439 (31%), Positives = 718/1439 (49%), Gaps = 109/1439 (7%) Query: 39 FVADNKEMYVKGMIQT--RENDKVIVKTLDDRM---LTLNNDQVFPM-NPPKFDKIEDMA 92 ++ D +E++ I R DKV+ L+D ++N + + P+ NP D+ Sbjct: 14 WIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDLT 73 Query: 93 MMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEA 151 +++LHEPAVL+NL+ R+A + +IYTYSG+ V +NPYK LP+Y ++ AY G+ + Sbjct: 74 ALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDM 133 Query: 152 PPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQP 211 PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFAT++ +G Sbjct: 134 DPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH---- 189 Query: 212 GKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 271 +ED+++ +NP+ EA GNAKT RNDNSSRFGK+ I F ++ A++ TYLLE Sbjct: 190 ------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243 Query: 272 KSRVTFQLSSERSYHIFYQIMSN-KKPELIDLLLISTNPFDFPFVSQGEVTVASIDDSEE 330 KSRV FQ +ER+YHIFYQ+ ++ ++ E L L S F++ + G + ++D E Sbjct: 244 KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302 Query: 331 LLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLM 390 ++ T +LGF + ++ ++K+ A++H GN++ E + + L+ Sbjct: 303 MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362 Query: 391 GLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD 450 GL S + + LC ++ +E V K Q N+ ALAK +Y +F ++V RINQ L Sbjct: 363 GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422 Query: 451 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510 + FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482 Query: 511 EFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKP 570 IDF D I+LIE MGI +L+EEC+ P TD ++ KLY+ + ++ F+KP+ Sbjct: 483 TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR- 540 Query: 571 AKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF------- 623 + F + H+A V+Y G+L+KN+D + + +V + + S L + F Sbjct: 541 ---MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597 Query: 624 SNYAGAETGDSGGSKKGGKKKGSSFQ-TVSAVFRENLNKLMTNLRSTHPHFVRCLIPNET 682 S + T S +K+ K F+ TV + FR +L LM L +T PH+VRC+ PN+ Sbjct: 598 SPFGSMITVKS--AKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655 Query: 683 KTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDS 742 K P D ++ QLR GVLE IRI + +PSR Y +F RY IL E F D Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713 Query: 743 KNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMR 802 K + +L+ + D Q++FG TK+FF+AG + LE++R +KL Q RG+L R Sbjct: 714 KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773 Query: 803 VEFKKMMERRDSIFCIQYNIRSFMNVK--------HWPWMNLFFKIK---PLLKSAEAEK 851 KK + R + IQ R V+ W + + L++S Sbjct: 774 ---KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830 Query: 852 EMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEG 911 MAT+ ++ LAR RK LEE +LQ+ L A R + Sbjct: 831 RMATITMQ-AYSRGFLAR-RRYRKMLEEHKAVILQKYARAWL-----------ARRRFQS 877 Query: 912 LIK--SKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVE 969 + + I L +V+ L ++LE++ + N LV K +L + I LE L K Sbjct: 878 IRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAA 937 Query: 970 KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINA 1029 + E K K + A+EE ++KL K L+ +Q I Sbjct: 938 THRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQ-----------------IQL 977 Query: 1030 KLEQQTDDLEGSLEQ-EKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKE 1088 KL+++T++L+ ++ K+L D+++ +R+ K + D E Q ++E++K + Sbjct: 978 KLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALK 1037 Query: 1089 FELSQLQAKIDDEQVHSLQFQKKIKELQAR---IEELEEEIEAEHTLRAKIEKQRSDLAR 1145 E QLQ ++ E V S + ++ L + I E E+EIE + +EK R Sbjct: 1038 DEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKR 1097 Query: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVA 1205 E+ E+ S T +E + + DLE E A K+A V Sbjct: 1098 EMR------EKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151 Query: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK---SKSNIERTCRTVEDQFSE 1262 E + Q K EKE L ++ ++ I L K +++I + R + + Sbjct: 1152 E-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTS 1206 Query: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEK-ESLISQLTKSKQALTQQLEELKR 1321 Q I +L QK L+ + E + +++ K E L +QL +S++ Q + L+ Sbjct: 1207 ENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEA 1266 Query: 1322 QMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET 1381 Q E TK K + +Q + D L++Q+E E E K ++ S+ E + E Sbjct: 1267 QNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEEL 1324 Query: 1382 DAIQRT-EELEEAKKKLAQRLQEAEENTETANSK--CASLEKTKQRLQGEVEDLMRDLE 1437 D R ++L++ K L++ + +A + ++ K L+ ++ +++L+ DL+ Sbjct: 1325 DMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383 Score = 92.4 bits (228), Expect = 4e-18 Identities = 117/535 (21%), Positives = 240/535 (44%), Gaps = 63/535 (11%) Query: 1312 LTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSE 1371 LT +++ L++++E++ K + + L S L E+ Q+ +AEL++A Sbjct: 887 LTYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA------- 936 Query: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVED 1431 A R YE + + +EE KL + E E E K L++ + L+ ++++ Sbjct: 937 -ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLK---LQEKTEELKEKMDN 992 Query: 1432 LMRDLERSHTACATLDKKQRNFDKVLAEWKQK-LDESQAELEAA--QKESRSLSTELFKM 1488 L + L FD V E +Q+ L E EL+ +K+ +SL E+ + Sbjct: 993 LTKQL----------------FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKAL 1036 Query: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548 ++ ++ +E + L+ E++ L++Q+ K + E EK +L++ +K D++ + Sbjct: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHV 1092 Query: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQR--AAEALQS--- 1603 + + + + S+I + LE ++ R +E ++E L + + A E L+ Sbjct: 1093 QSQKREMREKMSEITKQLLESYDIEDVRSRLSVE---DLEHLNEDGELWFAYEGLKKATR 1149 Query: 1604 VLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDD 1663 VL++ +S+ D E ++ + ++ H ++++ QK R + + +S H Sbjct: 1150 VLESHFQSQKDCY------EKEIEALNFKVVHLSQEINHLQKLFRE-ENDINESIRHEVT 1202 Query: 1664 ALRSNE----DLKEQLAIVERRNG----LLLEELEEMKVALEQTERTRRLSEQELLDASD 1715 L S D K+Q++ +E++ L E+ E+MK LE+ S++E + + Sbjct: 1203 RLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQ 1260 Query: 1716 RVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKK 1775 R + L +QN K+KL I + Q ++ ++ E +A+ + E + Sbjct: 1261 R-KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD 1319 Query: 1776 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENEL 1830 ++ +R+ K L+ VK L + +A + G K+ + RE E +L Sbjct: 1320 LEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374 Score = 73.9 bits (180), Expect = 1e-12 Identities = 119/574 (20%), Positives = 242/574 (42%), Gaps = 118/574 (20%) Query: 1346 LLREQYEEE-QEAKAELQRALSKANSEVAQWRTKYETDAIQR---TEELEEAKKKLAQRL 1401 L R +Y + +E KA + + ++A W + +I+R +L ++L ++L Sbjct: 845 LARRRYRKMLEEHKAVILQKYARA------WLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898 Query: 1402 QEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWK 1461 ++ + K SL + +++ L +LE++ T ++K + + + E Sbjct: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958 Query: 1462 QKLDESQAELEAAQKESRSLSTE------LFKMRNAYEEVVD------------------ 1497 KL + +ELE QKE L + KM N +++ D Sbjct: 959 AKLQKHNSELE-TQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFEL 1017 Query: 1498 -------QLETLRRENKNLQEEISDLT-----EQIAETG------------KNLQEAEKT 1533 Q+++L+ E K L++E L E + G K + E EK Sbjct: 1018 KTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKE 1077 Query: 1534 KKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRN 1593 +L++ +K D++ ++ + + + S+I + LE ++ R + E++E L + Sbjct: 1078 IELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSV---EDLEHLNED 1134 Query: 1594 SQR--AAEALQS---VLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR 1648 + A E L+ VL++ +S+ D E ++ + ++ H ++++ QK R Sbjct: 1135 GELWFAYEGLKKATRVLESHFQSQKDC------YEKEIEALNFKVVHLSQEINHLQKLFR 1188 Query: 1649 TVQGQLKDSQLHLDDALRSNE----DLKEQLAIVERRNG----LLLEELEEMKVALEQTE 1700 + + +S H L S D K+Q++ +E++ L E+ E+MK LE+ Sbjct: 1189 E-ENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELS 1247 Query: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 S++E + + R + L +QN I+TK+K ++ + IQE + A + K Sbjct: 1248 NQLHRSQEE--EGTQR-KALEAQNE--IHTKEK---------EKLIDKIQEMQEASDHLK 1293 Query: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 K + + E + + + L +DL+ LD +++ I+KL+ Sbjct: 1294 K----------QFETESEVKCNFRQEASRLTLENRDLEEELDMKDRV--------IKKLQ 1335 Query: 1821 NRVRELENEL----DVEQKRGAEALKGAHKYERK 1850 ++V+ L + DV G + G +Y+R+ Sbjct: 1336 DQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRE 1369 Score = 46.2 bits (108), Expect = 3e-04 Identities = 53/263 (20%), Positives = 111/263 (42%), Gaps = 32/263 (12%) Query: 1658 QLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRV 1717 Q L+D + N L E+L + +E++++++ LE+ RR E++ D V Sbjct: 895 QKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV 954 Query: 1718 QLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQ 1777 + + L +LE Q Q +++ +E + + K + D +++KE+ Sbjct: 955 E---EKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD------DVQKEE 1005 Query: 1778 DTSAHLERMKKNLEQTVKDLQHRLDEAEQ--LALKGGKKQIQKLENRVRELENELDVEQK 1835 LE K+ E +D + ++ ++ ALK K Q+Q L + L E Sbjct: 1006 RQRMLLE---KSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVA 1062 Query: 1836 RGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANT 1895 R ++ +K ++E++++ + Q + K+ V+S KR+ E + Sbjct: 1063 RLSKQVKTISEFEKEIELLQAQKIDVEKH--------------VQSQKREMREKMSEITK 1108 Query: 1896 QLSRCRRVQHELEEAAERADIAE 1918 QL +++E+ R + + Sbjct: 1109 QLLE----SYDIEDVRSRLSVED 1127 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 605 bits (1560), Expect = e-172 Identities = 450/1466 (30%), Positives = 720/1466 (49%), Gaps = 170/1466 (11%) Query: 81 NPPKFDKIEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEV 139 NP D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y ++ Sbjct: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123 Query: 140 VAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATI 199 + AY G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+ Sbjct: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183 Query: 200 AVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 259 + + + +E++++ +NP++E+ GNAKT RNDNSSRFGK+I I F + Sbjct: 184 SGSAS----------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYR 233 Query: 260 LASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDFPFVSQG- 318 + A++ TYLLEKSRV FQ ER+YHIFYQ+ ++ K +L + N +F + QG Sbjct: 234 IIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGG 292 Query: 319 EVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPD 378 + +DD++E+ T A +LG S ++GI+++ ++H GN+ F + + P Sbjct: 293 SPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPP 352 Query: 379 GTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMF 438 E LMG++ EM LC ++ E K + Q TN+ ALAK +Y K+F Sbjct: 353 KHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLF 412 Query: 439 LWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVL 498 W+V +NQ L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F L Sbjct: 413 NWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKL 472 Query: 499 EQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQH 558 EQEEY KE I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ H Sbjct: 473 EQEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531 Query: 559 LGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKL 618 L K F+KP+ KA F + H+A V+Y G+L+KNKD + E + + + S K+ Sbjct: 532 LNKCALFEKPR-LSNKA---FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKM 587 Query: 619 LSFLFSNYAGAETGDSGGSK---------------KGGKKKGSSFQTVSAVFRENLNKLM 663 L LF + A + S S + G+ +TV FR +L+ LM Sbjct: 588 LPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLM 647 Query: 664 TNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFK 723 L +T PH+VRC+ PN+ K P D + QLR GVLE IRI GFPSR Y +F Sbjct: 648 ETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFF 707 Query: 724 QRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDE 783 RYR+L + D K + +L + +D+++++FG TK+FF+AG + LE++R + Sbjct: 708 SRYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRAD 764 Query: 784 KLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFM---------NVKHWPWM 834 KL Q RG+L+R KK + R + +Q +R + K + Sbjct: 765 KLRAACIRIQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATII 821 Query: 835 NLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQE------- 887 ++++ + + + + + + + R LAR+ R+ E K V + + Sbjct: 822 QKYWRMYVVRRRYKIRRAATIVLQSYLR--GFLARNRYRKILREHKAVIIQKRVRGWLAR 879 Query: 888 ---KNDL-----------QLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE 933 K + ++ + E + L E K I +E K+ +L +++E+ Sbjct: 880 THYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQ 939 Query: 934 EEMNSELVAKKRNLE----DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989 + LV K NLE + L+ D++ L+L+ E+E +V +L EE+ L Sbjct: 940 NKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKL 995 Query: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049 +++ + EKK ++E + Q E V+ L + N L+Q+ + L + Q+ K Sbjct: 996 RKDLEQTRSEKKCIEEHADRY---KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052 Query: 1050 ADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQ 1109 E ++KL + K + +DL +++ + + L E S+L+ + DD + Sbjct: 1053 T--ETMEKKLVEETKQLE---LDLNDERLRYQNLLN----EFSRLEERYDDLKEEMTLMV 1103 Query: 1110 KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMN- 1168 K R + E+E+ ++I E+E+I R EE S ++M+ Sbjct: 1104 HVPKPGHKRTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEPS-EKKVPLDMSL 1154 Query: 1169 ----KKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKE 1224 +KR E ++ ++ +++ + E + K+ + G +++ +Q+LE E Sbjct: 1155 FLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE 1214 Query: 1225 KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284 +LK E++++ +ALS E E+ A +++ + +L Sbjct: 1215 NKKLKNELNELR---KALS-------------EKSAPEVTAPGAPAYRVLME------QL 1252 Query: 1285 QTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEET---------KAKNAMAH 1335 + + EL R EE L SQL K+A+ Q ++ K M + T K K +A Sbjct: 1253 TSVSEELDVRKEEVLILRSQLVSQKEAI--QPKDDKNTMTDSTILLEDVQKMKDKGEIAQ 1310 Query: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395 A + LL Q + ++ + AL E+ + EE ++ Sbjct: 1311 AYIGLKETNRLLESQLQSQKRSHENEAEAL---RGEIQSLK-----------EENNRQQQ 1356 Query: 1396 KLAQRLQ-EAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFD 1454 LAQ LQ E E ASL+ RL E DLM LE+ DK R Sbjct: 1357 LLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQ-------DKTVRKLK 1403 Query: 1455 KVLAEWKQKLDESQAELEAAQKESRS 1480 K L + +K+ ELE Q E+ S Sbjct: 1404 KQLKVFAKKI----GELEVGQMENIS 1425 Score = 77.0 bits (188), Expect = 2e-13 Identities = 133/667 (19%), Positives = 284/667 (42%), Gaps = 101/667 (15%) Query: 852 EMATMKEDFERTKEELARSEARRKELEEKMVSLLQE----KNDLQLQVQSETENL----- 902 E ++ D ER L SE K +++SL +E + DL+ Q +SE + + Sbjct: 960 ETEKLRSDLER----LQLSEEEAKVATGRVLSLQEEIAKLRKDLE-QTRSEKKCIEEHAD 1014 Query: 903 ---MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959 + E+ L + LL+ + + L R+ ++ + +E + KK L ++ L+ D++ Sbjct: 1015 RYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKK--LVEETKQLELDLN 1072 Query: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019 D L + E E + +L EEMT + + K ++ + + + Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLKEEMTLMVH----VPKPGHKRTDSTHSSNESEYIFSS 1128 Query: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079 ++ + I ++ E+ + EKK+ D+ LK+ Q+ + +LE +KQ Sbjct: 1129 EIAEMEDIPSRTEEPS---------EKKVPLDMSLF-------LKL-QKRVTELEQEKQV 1171 Query: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE-EEIEAEHTLRAKIEK 1138 ++++L +KE ++ + +AK ++ + +I+ + E L+ +E+E+E+ K++ Sbjct: 1172 MQDELDRKEEQVLRSKAKEEE--------RPQIRGAELEYESLKRQELESEN---KKLKN 1220 Query: 1139 QRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA---AT 1195 + ++L + L E S A GA + ++ M + + R E L+ + + A Sbjct: 1221 ELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI 1280 Query: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255 K +++ + ++++Q++K K E ++ + ++ + + S+ +S+ E Sbjct: 1281 QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSH-ENEAEA 1339 Query: 1256 VEDQFSEIKAKDEQQTQLI-------------HDLNMQKARLQTQNGELSHRVEEKESLI 1302 + + +K ++ +Q QL+ L + RL +N +L ++E+++ + Sbjct: 1340 LRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTV 1399 Query: 1303 SQLTKSKQALTQQLEELK-RQMEEETKAK--NAMAHALQSSRHDCD---LLREQYEEEQE 1356 +L K + +++ EL+ QME + + + + R + D +L + E+EQ+ Sbjct: 1400 RKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQK 1459 Query: 1357 AKAELQRALSKANSEV-----------------AQWRTKYETDAIQRTEELEEAKKKLAQ 1399 L L V A + + T + KK L + Sbjct: 1460 LVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKK 1519 Query: 1400 RLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAE 1459 R + E + ++ C L KQ GE + + R + C T NFD LAE Sbjct: 1520 RGDDFETVSFWLSNTCRFLHCLKQ-YSGEEGFMKHNTSRQNEHCLT------NFD--LAE 1570 Query: 1460 WKQKLDE 1466 ++Q L + Sbjct: 1571 YRQVLSD 1577 Score = 72.8 bits (177), Expect = 3e-12 Identities = 132/635 (20%), Positives = 247/635 (38%), Gaps = 139/635 (21%) Query: 1084 LKKKEFELSQLQAK-IDDEQVHSLQFQKKIKELQARIEE--------LEEEIEAEHTLRA 1134 + K+E + +++A+ ++ + + + KI +LQ +++E +E+ E + Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959 Query: 1135 KIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194 + EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + + Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009 Query: 1195 TLRKKQADSVAELGEQ-IDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253 ++ AD + EQ + NL+ L++EK L I A + Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMT------------- 1053 Query: 1254 RTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313 T+E K E+ QL DLN ++ R Q E S E + L ++T L Sbjct: 1054 ETME------KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102 Query: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVA 1373 + + + + T + N + S + + + + EE E K L +L + Sbjct: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK-- 1160 Query: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLM 1433 R ELE+ K+ + L EE + +K E+ + +++G Sbjct: 1161 ------------RVTELEQEKQVMQDELDRKEEQVLRSKAK----EEERPQIRGA----- 1199 Query: 1434 RDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYE 1493 +LE L+ + + L E ++ L E A A AY Sbjct: 1200 -ELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP------------AYR 1246 Query: 1494 EVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553 +++QL ++ E +EE+ L Q+ + +Q + + +D + LE+V+ Sbjct: 1247 VLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTM-----TDSTILLEDVQK 1301 Query: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRN 1613 ++ +I + + L + L+ +++ KR+ + AEAL+ EI+S Sbjct: 1302 M--KDKGEIAQAYIGLKETNRLLE-------SQLQSQKRSHENEAEALRG----EIQSLK 1348 Query: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673 + +NRQ QL L L R L+ Sbjct: 1349 E--------------------ENNRQQ------------QLLAQNLQLPPEARIEASLQH 1376 Query: 1674 QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQ 1708 ++ + N L+E+LE +Q + R+L +Q Sbjct: 1377 EITRLTNENLDLMEQLE------KQDKTVRKLKKQ 1405 Score = 71.6 bits (174), Expect = 7e-12 Identities = 137/621 (22%), Positives = 269/621 (43%), Gaps = 69/621 (11%) Query: 1026 KINAKLEQQTDDLEG-SLEQEKKLRADLE----RAKRKLEG---DLKMSQESIMDLENDK 1077 ++ AK E + +E S+E+ KKL +E + +RK++ D K E + +LE Sbjct: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957 Query: 1078 QQIEEKLKK--KEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK 1135 EKL+ + +LS+ +AK+ +V SLQ + I +L +++E + + Sbjct: 958 NSETEKLRSDLERLQLSEEEAKVATGRVLSLQEE---------IAKLRKDLEQTRSEKKC 1008 Query: 1136 IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195 IE+ +E E++ L+E + + +++EA ++ + +E T T Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL------LKQEKEALNHRIVQQAKEMT-------ET 1055 Query: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK-SKSNIERTCR 1254 + KK + +L +++ + Q L E S L+ DD+ + + K +RT Sbjct: 1056 MEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDS 1115 Query: 1255 TVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEK-ESLISQLTKSKQALT 1313 T SE E + D+ + + L + K + +++L + KQ + Sbjct: 1116 THSSNESEYIFSSEIAE--MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQ 1173 Query: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKA-----ELQRALSKA 1368 +L+ + Q+ +KAK ++ + + + L+ Q E + K EL++ALS+ Sbjct: 1174 DELDRKEEQVLR-SKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEK 1232 Query: 1369 NSE--VAQWRTKYETDAIQRT---EELEEAKKK---LAQRLQEAEENTETANSKCASLEK 1420 ++ A Y Q T EEL+ K++ L +L +E + + K + Sbjct: 1233 SAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDS 1292 Query: 1421 TKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDES-QAELEAAQKESR 1479 T +ED+ + ++ A A + K+ N ++L Q S + E EA + E + Sbjct: 1293 TIL-----LEDVQKMKDKGEIAQAYIGLKETN--RLLESQLQSQKRSHENEAEALRGEIQ 1345 Query: 1480 SLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ 1539 SL E + + + + QL R +LQ EI+ LT + + +++ EK K V + Sbjct: 1346 SLKEENNRQQQLLAQNL-QLPPEARIEASLQHEITRLTNENLDL---MEQLEKQDKTVRK 1401 Query: 1540 EKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDR--KVIEKDEEIEQLKRNSQRA 1597 K L+V +++ G LE + + + Q+ E R + K+++ + + + Sbjct: 1402 LKKQLKVFAKKI-GELEVGQME----NISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKED 1456 Query: 1598 AEALQSVLDAEIRSRNDALRL 1618 + L L E++ R A+ L Sbjct: 1457 EQKLVKNLILELKPRGVAVNL 1477 Score = 53.1 bits (126), Expect = 3e-06 Identities = 92/477 (19%), Positives = 212/477 (44%), Gaps = 61/477 (12%) Query: 1462 QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIA 1521 +KL +E +K + ++ +++ +E + L + NL+ + TE++ Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965 Query: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581 + LQ +E+ K+ LQ +I +++ +L Q +SE +K I Sbjct: 966 SDLERLQLSEEEAKVATGRVLSLQ--------------EEIAKLRKDLEQTRSE--KKCI 1009 Query: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMA 1641 E E ++ K+ +++ L + ++ N L+ +K+ LN +Q ++M Sbjct: 1010 E--EHADRYKQETEQ--------LVSNLKEENTLLKQEKEA---LNHRIVQ---QAKEMT 1053 Query: 1642 ETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM----KVALE 1697 ET + + + + K +L L+D ++L + + +E R L EE+ M K + Sbjct: 1054 ETME--KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHK 1111 Query: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757 +T+ T +E E + +S+ ++ + + ++KK+ D++ Sbjct: 1112 RTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL--------------- 1156 Query: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817 K +K +T+ + ++ E D K E+ ++ E E L + + + + Sbjct: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENK 1216 Query: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQA 1877 KL+N + EL L E+ GA Y ++++T +EE ++ + + L+ L++ Sbjct: 1217 KLKNELNELRKALS-EKSAPEVTAPGAPAYRVLMEQLTSVSEE--LDVRKEEVLI--LRS 1271 Query: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934 ++ S K +A + ++ NT ++ + ++++ ++ +IA++ + L+ +R + SQ Sbjct: 1272 QLVSQK-EAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYIG-LKETNRLLESQ 1325 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 582 bits (1499), Expect = e-165 Identities = 458/1587 (28%), Positives = 768/1587 (48%), Gaps = 191/1587 (12%) Query: 55 RENDKVIVKTLDDRML------TLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKE 108 +E DK + L+D + N F NP D+ +++LHEPAVL+NLK Sbjct: 32 KEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKV 91 Query: 109 RYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFML 167 R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+ + PHIF++++ AY+ M Sbjct: 92 RFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMA 151 Query: 168 TDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANP 227 D NQSI+++GESGAGKTV+ K ++YFAT+ G ET +E++++ ++P Sbjct: 152 RDEKNQSIIVSGESGAGKTVSAKYAMRYFATV---GGSASETN-------IEEKVLASSP 201 Query: 228 LLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHI 287 ++EA GNAKT RNDNSSRFGK+I+I F + A++ TYLLEKSRV FQ ER+YHI Sbjct: 202 IMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQADDERNYHI 261 Query: 288 FYQIMSNKK-PELIDLLLISTNPFDFPFVSQG-EVTVASIDDSEELLATDNAIDILGFSS 345 FYQ+ + PE +L L S DF + SQG + ++ +DD+E+ T A +LG Sbjct: 262 FYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKE 319 Query: 346 EEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VADKAGYL------MGLNSAEM 397 ++ I+K+ +++H G++ QAE DG ++ + YL +G+ ++M Sbjct: 320 SHQMSIFKIIASILHLGSVAI-------QAERDGDSCSISPQDVYLSNFCRLLGVEHSQM 372 Query: 398 LKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQY 457 LC ++ +E K ++QQV N+ ALAK +Y ++F W+V IN+ L T + Sbjct: 373 EHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLKQHS 432 Query: 458 FIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGM 517 FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W IDF Sbjct: 433 FIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDF-Y 491 Query: 518 DLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEA 577 D CI+LIE +GI +L+EEC PK TD ++ KLYD+H S +FQKP+ + Sbjct: 492 DNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPR----MSNT 546 Query: 578 HFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF---SNYAGAETGDS 634 F +VH+A V+Y G+L+KN+D + E + + + S L++ LF + A T Sbjct: 547 AFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGK 606 Query: 635 GGSKKGGKKKG---------SSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTP 685 G S K + +TV FR +L+ LM L +T PH+VRC+ PN+ K P Sbjct: 607 GSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLP 666 Query: 686 GVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA 745 D + QLR GVLE IRI G+PSR Y DF RYR+L E D K Sbjct: 667 FHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR--ELANTDKKAI 724 Query: 746 SEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEF 805 +L ++ D ++F+FG TK+FF+AG + LE++R +K T Q RG+L +V++ Sbjct: 725 CRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKY 784 Query: 806 KKMMERRDSI--FCIQYNIR----SFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKED 859 ++ ++ +C + R ++ + ++++ ++ + + A + + Sbjct: 785 HRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQA 844 Query: 860 FERTKEELARSEARRKELEEKMVSL------------LQEKNDLQLQVQ---------SE 898 F T+ R R+ +E K ++ Q D + +Q E Sbjct: 845 F--TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE 902 Query: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958 + L E L + + +E KV +L +++E+ N E L S+ ++ Sbjct: 903 LKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ---NKEFKTLSEQLSVTTSTYTMEV 959 Query: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018 + L+ L V ++ E+ L EE+ +L + + E+K L++AH + D+L Sbjct: 960 ERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDEL---- 1013 Query: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND-- 1076 +K ADLE+ L+ + + I+ D Sbjct: 1014 ---------------------------RKRVADLEQENALLKDEKEQLNNQILCQSKDEF 1046 Query: 1077 -KQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK 1135 + ++E L KKE E +E+ K+ +L+ R + L +E+ Sbjct: 1047 AQNSVKENLMKKELE---------EERSRYQNLVKEYSQLEQRYDNLRDEM--------T 1089 Query: 1136 IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195 I KQ R S +++ + + E+ +A + +EE L+ A T Sbjct: 1090 IIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA-----LQQVEEIGLEKAAMDMT 1144 Query: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255 + K V EL ++ LQ +K E++ S+ K++ + ++I+ N + + Sbjct: 1145 VFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDIDL----DPNADLAYNS 1199 Query: 1256 VEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQ 1315 ++ Q E+++++++ +++L A TQN + L++QL + + L + Sbjct: 1200 LKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVR 1257 Query: 1316 LEE---LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372 EE L+ Q+ + + A +A + + +QE E + + NS+ Sbjct: 1258 KEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKT 1317 Query: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQ--RLQEAEENTETANSKCASLEKTKQRLQGEVE 1430 W + EL A + L Q RL EA+ ++ E+ + L+ ++E Sbjct: 1318 EDW------GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEH-----EEEVEHLKAQLE 1366 Query: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRN 1490 L + +DK+Q+ F + L E+Q E Q+ SR L+ E ++ Sbjct: 1367 ALKEE----------MDKQQQTFCQTLL----LSPEAQVEFGVQQEISR-LTNENLDLKE 1411 Query: 1491 AYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE 1550 E++ L+++ K ++ DL E + L ++E+ + + ++ + +Q ++ Sbjct: 1412 LVEKLEKNERKLKKQLKIYMKKAQDL-----EAAQALAQSERKRHELNRQVT-VQRKEKD 1465 Query: 1551 VEGSLE-HEESKILRVQLELSQVKSEL 1576 +G LE H+E + L ++ ++ +K ++ Sbjct: 1466 FQGMLEYHKEDEALLIRNLVTDLKPQM 1492 Score = 73.9 bits (180), Expect = 1e-12 Identities = 124/562 (22%), Positives = 231/562 (41%), Gaps = 86/562 (15%) Query: 1360 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLE 1419 +LQR + + N E + T E+E KK+L Q E+T Sbjct: 929 QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSL--------- 979 Query: 1420 KTKQRLQGEVEDLMRDLERSHTACATL-DKKQRNFDK-------------VLAEWKQKLD 1465 RLQ EVE L +L+R+H+ L D R D+ +L + K++L+ Sbjct: 980 ----RLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLN 1035 Query: 1466 ES---QAELEAAQKESRS--LSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTE-- 1518 Q++ E AQ + + EL + R+ Y+ +V + L + NL++E++ + + Sbjct: 1036 NQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTP 1095 Query: 1519 ---QIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSE 1575 + +L+ + E D + AL++VE + + + V L+L + E Sbjct: 1096 GHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155 Query: 1576 L--DRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRS--------RNDALRLKKKMEGD 1625 L +RK ++ E + + + + AE Q+ +D + + R + KK++ D Sbjct: 1156 LEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKND 1215 Query: 1626 LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDL---KEQLAIVERRN 1682 LNE+ + +A+ + G L L+ ++E+L KE++ I+ + Sbjct: 1216 LNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQ- 1267 Query: 1683 GLLLEELEEMKVALEQTE-----RTRRLSEQELLDASDRVQLLHS--QNTSLINTKKKLE 1735 + ++ ++A E R+ + ++ +D D ++ H Q S L Sbjct: 1268 ---IVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLN 1324 Query: 1736 AD---------IAQCQAEVENSIQ-ESRNAEEKAKKAITDAAMMAEELKKEQDTSAH--L 1783 D + Q +E +Q +S EE+ + + EE+ K+Q T L Sbjct: 1325 EDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLL 1384 Query: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRG--AEAL 1841 + +E V+ RL E L L K+ ++KLE R+L+ +L + K+ EA Sbjct: 1385 LSPEAQVEFGVQQEISRLTN-ENLDL---KELVEKLEKNERKLKKQLKIYMKKAQDLEAA 1440 Query: 1842 KGAHKYERKVKEMTYQAEEDHK 1863 + + ERK E+ Q K Sbjct: 1441 QALAQSERKRHELNRQVTVQRK 1462 Score = 48.5 bits (114), Expect = 6e-05 Identities = 78/364 (21%), Positives = 149/364 (40%), Gaps = 67/364 (18%) Query: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDA----EIRSRNDA 1615 ++ + V+ QV E I+K +R+ QR +A + A + R A Sbjct: 846 TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKA 905 Query: 1616 LRLKKKMEGDLNEMEIQLGHS----NRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDL 1671 LR++ + L + + + + R++ E K +T+ QL + E L Sbjct: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLS---VTTSTYTMEVERL 962 Query: 1672 KEQLAIVERRNG-----LLLEELEEMKVALEQTERTRRLSE----QELLDASDRVQLLHS 1722 K++L ++ G L EE+E ++ L++ R++ E +E + RV L Sbjct: 963 KKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQ 1022 Query: 1723 QNTSLINTKKKLEADIAQCQAEVE---NSIQESRNAEEKAKKAITDAAMMAEELKKEQDT 1779 +N L + K++L I CQ++ E NS++E+ +M +EL++E+ Sbjct: 1023 ENALLKDEKEQLNNQIL-CQSKDEFAQNSVKEN---------------LMKKELEEERSR 1066 Query: 1780 SAHLERMKKNLEQTVKDLQ-----------HRLDEAEQLALKGGKKQIQKLENRVRELEN 1828 +L + LEQ +L+ HR + + Q +L+ + + + E+ Sbjct: 1067 YQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTED 1126 Query: 1829 ELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEE 1888 L ++ G E +A D L+LQ V +L+ + K + Q E+ Sbjct: 1127 ALQQVEEIGLE-----------------KAAMDMTVFLKLQKRVRELEQERKKLQVQLEK 1169 Query: 1889 AEEQ 1892 E+Q Sbjct: 1170 REQQ 1173 Score = 37.4 bits (85), Expect = 0.14 Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 27/166 (16%) Query: 1773 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDV 1832 L+ E ++ HL+R+ +E V LQ ++DE K+ + L ++ + + Sbjct: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ--------NKEFKTLSEQLSVTTSTYTM 957 Query: 1833 EQKRGAEALKGAHKYERKVKEMT-YQAEEDHKNILRLQDLVDKLQAKVK---SYKRQAEE 1888 E ER KE+ YQ LRLQ+ V+ L+ +++ S ++ E+ Sbjct: 958 E-------------VERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004 Query: 1889 AEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934 A + +L +RV +E A D E N++ +S+D +Q Sbjct: 1005 AHSREKDELR--KRVADLEQENALLKDEKEQLNNQILCQSKDEFAQ 1048 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 511 bits (1315), Expect = e-144 Identities = 410/1672 (24%), Positives = 815/1672 (48%), Gaps = 192/1672 (11%) Query: 66 DDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVT 125 D +L ++ D V N P D++ED+A + +L+E +VL+ L++RY A +++TY+G + Sbjct: 385 DGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLV 444 Query: 126 VNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGK 185 + P VY +V+ ++G +R++ PHI++++ AY+ ML R +QSI++ G SG+GK Sbjct: 445 LGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGK 504 Query: 186 TVNTKRVIQYFATIA-VTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244 T + + ++QY ATIA ++G+K + + TL LEAFGN+ T+ N N++ Sbjct: 505 TTSCQHLVQYLATIAGISGNKVFSVEKWQALYTL----------LEAFGNSPTIINGNAT 554 Query: 245 RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS----NKKPELI 300 RF + + + F G++ASA I+T LLEK RV + +SE ++++FY +++ + EL Sbjct: 555 RFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELH 614 Query: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360 L N F +++ E + +L A A+ +LG S +E+ + + A+ H Sbjct: 615 LNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWFILAAIYH 671 Query: 361 YGNMKFKQKQREEQAEPDGT-EVADKAGYLMGLNSAEMLKGLCCPRVKVG----NEYVTK 415 G ++ E + E A KA YL+G + E+ + + K G + + Sbjct: 672 LGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQ 731 Query: 416 GQNVQQVTNSVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIA 465 G + + G +A +Y ++F +V+ +N+ L + Q + ++D Sbjct: 732 GPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTP 791 Query: 466 GFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDF---- 515 GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE F D Sbjct: 792 GFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPT 851 Query: 516 -----GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564 +D A+ L+ ++ G+ +LEEE + P A++ + +L+ + + + Sbjct: 852 DDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGD 911 Query: 565 FQKPKPAKGKAEAH-FSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVGLYQKSSLKLLS 620 + P ++ H F L H GT V+YN+ GWL+ K +P + L Q S K++S Sbjct: 912 KKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIIS 971 Query: 621 FLFSNYAGAET-------GDSGGSKKGGKKKGSSFQT----VSAVFRENL--------NK 661 LF AG+ T G GGS+ ++ S +T ++AV +++L + Sbjct: 972 NLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDA 1031 Query: 662 LMTNLRSTHPHFVRCLIP--------------------NETKTPG---------VMDHYL 692 L+ ++ + HFV C +P +E P +D L Sbjct: 1032 LIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPL 1091 Query: 693 VMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ----FIDSKNASEK 748 + QLR + +L+ +R+ R+G+P +++++F++R+ +L + +D + A E+ Sbjct: 1092 LRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEE 1151 Query: 749 LLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKM 808 LL +D+++ G ++VFF+AG L LEE RDE+ +T QA CRGYL R FKK Sbjct: 1152 LLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKR 1211 Query: 809 MERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELA 868 + +I C+Q NI+ VK WPW LF ++PL++ +E+++ E+ ++ + +L Sbjct: 1212 KIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLE 1271 Query: 869 RSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELT- 927 ++E R EL L ++L ++ E A + + ++ E ++KEL Sbjct: 1272 KAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT 1331 Query: 928 --ERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL---TLTKVEKEKHATENKVKNL 982 + L+++ E+ V + R + + + + ++DD + K E+ + K L Sbjct: 1332 QYDALKKQMEVMEMEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389 Query: 983 SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGS 1041 +E E+ + + K+ L ++ L DLQ + E+ L ++ K ++ T +L+ + Sbjct: 1390 QQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442 Query: 1042 ---LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ---LQ 1095 LE ++ +LE+ +R+ + +L + E + + +K Q E+ ++K+ L++ L+ Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLK 1499 Query: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155 +++++ + F +K+ L+A ++++ + + AK++KQ DL ++++ E L+ Sbjct: 1500 QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559 Query: 1156 EASGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKQADSVAELGEQI 1211 E +G + + E E ++MR +++E + E + +KK +L E+ Sbjct: 1560 EQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY 1619 Query: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNI-----EALSKSKSNIERTCRTVEDQFSEIKAK 1266 ++ KQK+ +EK EL+ ++ ++ + E+ + + +++RT + D Sbjct: 1620 ED----KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD-------- 1667 Query: 1267 DEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326 QL+ D A + + +L +++EE E + K+++A+ ++E+L Q+++ Sbjct: 1668 ----AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723 Query: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQR 1386 KAK A+ L + + + ++ + EE+QE EL + K + VAQ Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------ 1768 Query: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446 A + LAQ + + + E AN + L++ Q LQ +VE LE+S + + Sbjct: 1769 ------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVE----FLEQSMVDKSLV 1817 Query: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506 +++ + E + +L+ + +++ + + L + K+ ++ + + +N Sbjct: 1818 SRQEAK----IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873 Query: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566 K LQ ++ D E++ E + EA + K +E + L+ A + ++ L+ +I +Q Sbjct: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933 Query: 1567 LEL-SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617 + +++S+ + +I +++ + + E S +D+E+ R D ++ Sbjct: 1934 AAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEG-DSDVDSELEDRVDGVK 1984 Score = 190 bits (483), Expect = 1e-47 Identities = 171/701 (24%), Positives = 332/701 (47%), Gaps = 64/701 (9%) Query: 1256 VEDQFSE--IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313 +E Q SE I+ KDE+ I L + + + + EL + ES IS+LT Sbjct: 1247 IEVQLSEEQIRNKDEE----IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER 1302 Query: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE 1371 E + ++ ET + ++ + D L++Q E E + +A L RA ++ N E Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361 Query: 1372 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEENTETA 1411 V +WR KYE + + E ++ K++L +RL + + ++E + Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421 Query: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 L+K QRL E++D LE L+KKQR FD L++ ++ + + Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481 Query: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531 E Q+E L E F ++ EE + ++ +L+ E+ D++ Q ++ +L + + Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541 Query: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591 K + +E + D + L+E G+++ E LR+++E+ +++ +++ +DEE+E+ + Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601 Query: 1592 RNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR--- 1648 ++ Q+ + ++ L+ E + LR K+++EG L + Q+ NR+ E++K LR Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKDL 1658 Query: 1649 -TVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE 1707 + L D+QL LD L+++ K ++A L +LEE + + R+ E Sbjct: 1659 KRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAME 1710 Query: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA---EVENSIQESR-NAEEKAKKAI 1763 E+ D LH Q + K LE +++ Q E++N ++E + + E KK Sbjct: 1711 VEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763 Query: 1764 TDAAMMAEELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 A + +L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E Sbjct: 1764 AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQE 1821 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 ++RELE L+ E+ + A + + ++++T + ++ R ++ +LQ +++ Sbjct: 1822 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1881 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921 K EE E A + R+ +HELE E + A + Sbjct: 1882 DTK---EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918 Score = 70.1 bits (170), Expect = 2e-11 Identities = 60/304 (19%), Positives = 145/304 (47%), Gaps = 9/304 (2%) Query: 1643 TQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERT 1702 +++ +R +++ + L+ A + +L+ +E R L EL + + E + Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311 Query: 1703 RRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ----AEVENSIQESRNAEE- 1757 E L A ++ L +Q +L + +E ++ + + AE+ + + E Sbjct: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371 Query: 1758 --KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKK 1814 K ++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKK 1430 Query: 1815 QIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDK 1874 + Q+L +++ + L+ +Q R E K +++ ++ + +A+ + +LQ D Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490 Query: 1875 LQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934 L A+ S K+Q EE + + ++ EL++ + + E+ + K++ + RD+ ++ Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550 Query: 1935 KMEE 1938 ++ Sbjct: 1551 VKDQ 1554 Score = 56.6 bits (135), Expect = 2e-07 Identities = 109/534 (20%), Positives = 222/534 (41%), Gaps = 63/534 (11%) Query: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQA---ELEAAQKESRSLSTELFK 1487 D MR + + + +R FD + +K + E A ++ L E Sbjct: 1103 DAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSS 1162 Query: 1488 MRNAYEEVVDQLETLRRENKNLQEEIS-DLTE-QIAETGKNLQEAEKTKKLVEQEKSDLQ 1545 V + TL R + E+ S +LT Q A G ++ K +K+ + +Q Sbjct: 1163 CCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQ 1222 Query: 1546 VALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVL 1605 +++ +G + K+ L +V+ + ++ KDEEI+QL+ ++A + Sbjct: 1223 KNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIRNKDEEIQQLRSKLEKAEKERN--- 1278 Query: 1606 DAEIRSRNDALRLK-KKMEGDLNEMEIQLGHSNRQM--AETQKHLRTVQGQLKDSQLHLD 1662 E+R +D L + ++ +L + E G S Q+ AET + LR + ++K+ Q D Sbjct: 1279 --ELRLNSDRLESRISELTSELTD-ERNTGESASQLLDAETAERLRA-EKEMKELQTQYD 1334 Query: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722 LK+Q+ ++E +E M+ L + + + DA +L + Sbjct: 1335 A-------LKKQMEVME---------MEVMEARLIRAAEINGEVDDD--DAGGEWRLKYE 1376 Query: 1723 QNTSLIN-TKKKLEADIA-------QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774 + ++ TKK+L+ + Q + ++E + + + E++++A+ + L Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436 Query: 1775 KE-QDTSAHLE-------RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK--LENRVR 1824 E QDT HLE ++K + +L +EA++ L+ K Q +K L Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496 Query: 1825 ELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKR 1884 L+ +L+ + A + E ++++++ Q +D ++ AKVK R Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL-----------AKVKKQLR 1545 Query: 1885 QAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 E + +L LE+A R ++ ++ + +K + +++EE Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 507 bits (1306), Expect = e-143 Identities = 411/1671 (24%), Positives = 810/1671 (48%), Gaps = 205/1671 (12%) Query: 66 DDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVT 125 D +L ++ D V N P D++ED+A + +L+E +VL+ L++RY A +++TY+G + Sbjct: 385 DGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLV 444 Query: 126 VNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGK 185 + P VY +V+ ++G +R++ PHI++++ AY+ ML R +QSI++ G SG+GK Sbjct: 445 LGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGK 504 Query: 186 TVNTKRVIQYFATIA-VTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244 T + + ++QY ATIA ++G+K + + TL LEAFGN+ T+ N N++ Sbjct: 505 TTSCQHLVQYLATIAGISGNKVFSVEKWQALYTL----------LEAFGNSPTIINGNAT 554 Query: 245 RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS----NKKPELI 300 RF + + + F G++ASA I+T LLEK RV + +SE ++++FY +++ + EL Sbjct: 555 RFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELH 614 Query: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360 L N F +++ E + +L A A+ +LG S +E+ + + A+ H Sbjct: 615 LNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWFILAAIYH 671 Query: 361 YGNMKFKQKQREEQAEPDGT-EVADKAGYLMGLNSAEMLKGLCCPRVKVG----NEYVTK 415 G ++ E + E A KA YL+G + E+ + + K G + + Sbjct: 672 LGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQ 731 Query: 416 GQNVQQVTNSVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIA 465 G + + G +A +Y ++F +V+ +N+ L + Q + ++D Sbjct: 732 GPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTP 791 Query: 466 GFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDF---- 515 GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE F D Sbjct: 792 GFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPT 851 Query: 516 -----GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564 +D A+ L+ ++ G+ +LEEE + P A++ + +L+ + + + Sbjct: 852 DDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGD 911 Query: 565 FQKPKPAKGKAEAH-FSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVGLYQKSSLKLLS 620 + P ++ H F L H GT V+YN+ GWL+ K +P + L Q S K++S Sbjct: 912 KKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIIS 971 Query: 621 FLFSNYAGAET-------GDSGGSKKGGKKKGSSFQT----VSAVFRENL--------NK 661 LF AG+ T G GGS+ ++ S +T ++AV +++L + Sbjct: 972 NLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDA 1031 Query: 662 LMTNLRSTHPHFVRCLIP--------------------NETKTPG---------VMDHYL 692 L+ ++ + HFV C +P +E P +D L Sbjct: 1032 LIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPL 1091 Query: 693 VMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ----FIDSKNASEK 748 + QLR + +L+ +R+ R+G+P +++++F++R+ +L + +D + A E+ Sbjct: 1092 LRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEE 1151 Query: 749 LLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKM 808 LL +D+++ G ++VFF+AG L LEE RDE+ +T QA CRGYL R FKK Sbjct: 1152 LLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKR 1211 Query: 809 MERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELA 868 + +I C+Q NI+ VK WPW LF ++PL++ +E+++ E+ ++ + +L Sbjct: 1212 KIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLE 1271 Query: 869 RSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELT- 927 ++E R EL L ++L ++ E A + + ++ E ++KEL Sbjct: 1272 KAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT 1331 Query: 928 --ERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL---TLTKVEKEKHATENKVKNL 982 + L+++ E+ V + R + + + + ++DD + K E+ + K L Sbjct: 1332 QYDALKKQMEVMEMEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389 Query: 983 SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGS 1041 +E E+ + + K+ L ++ L DLQ + E+ L ++ K ++ T +L+ + Sbjct: 1390 QQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442 Query: 1042 ---LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ---LQ 1095 LE ++ +LE+ +R+ + +L + E + + +K Q E+ ++K+ L++ L+ Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLK 1499 Query: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155 +++++ + F +K+ L+A ++++ + + AK++KQ DL ++++ E L+ Sbjct: 1500 QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559 Query: 1156 EASGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKQADSVAELGEQI 1211 E +G + + E E ++MR +++E + E + +KK +L E+ Sbjct: 1560 EQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY 1619 Query: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNI-----EALSKSKSNIERTCRTVEDQFSEIKAK 1266 ++ KQK+ +EK EL+ ++ ++ + E+ + + +++RT + D Sbjct: 1620 ED----KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD-------- 1667 Query: 1267 DEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326 QL+ D A + + +L +++EE E + K+++A+ ++E+L Q+++ Sbjct: 1668 ----AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723 Query: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQR 1386 KAK A+ L + + + ++ + EE+QE EL + K + VAQ Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------ 1768 Query: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446 A + LAQ + + + E AN + L++ Q LQ +VE LE+S + + Sbjct: 1769 ------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVE----FLEQSMVDKSLV 1817 Query: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506 +++ + E + +L+ + +++ + + L + K+ ++ + + +N Sbjct: 1818 SRQEAK----IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873 Query: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566 K LQ ++ D E++ E + EA + K +E + L+ A + ++ L+ +I +Q Sbjct: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933 Query: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617 + ++ E+ E DE + + S +D+E+ R D ++ Sbjct: 1934 ---AAIEDEM-----ESDENEDLINSEG-------DSDVDSELEDRVDGVK 1969 Score = 190 bits (483), Expect = 1e-47 Identities = 171/701 (24%), Positives = 332/701 (47%), Gaps = 64/701 (9%) Query: 1256 VEDQFSE--IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313 +E Q SE I+ KDE+ I L + + + + EL + ES IS+LT Sbjct: 1247 IEVQLSEEQIRNKDEE----IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER 1302 Query: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE 1371 E + ++ ET + ++ + D L++Q E E + +A L RA ++ N E Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361 Query: 1372 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEENTETA 1411 V +WR KYE + + E ++ K++L +RL + + ++E + Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421 Query: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 L+K QRL E++D LE L+KKQR FD L++ ++ + + Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481 Query: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531 E Q+E L E F ++ EE + ++ +L+ E+ D++ Q ++ +L + + Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541 Query: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591 K + +E + D + L+E G+++ E LR+++E+ +++ +++ +DEE+E+ + Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601 Query: 1592 RNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR--- 1648 ++ Q+ + ++ L+ E + LR K+++EG L + Q+ NR+ E++K LR Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKDL 1658 Query: 1649 -TVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE 1707 + L D+QL LD L+++ K ++A L +LEE + + R+ E Sbjct: 1659 KRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAME 1710 Query: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA---EVENSIQESR-NAEEKAKKAI 1763 E+ D LH Q + K LE +++ Q E++N ++E + + E KK Sbjct: 1711 VEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763 Query: 1764 TDAAMMAEELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 A + +L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E Sbjct: 1764 AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQE 1821 Query: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 ++RELE L+ E+ + A + + ++++T + ++ R ++ +LQ +++ Sbjct: 1822 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1881 Query: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921 K EE E A + R+ +HELE E + A + Sbjct: 1882 DTK---EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918 Score = 70.1 bits (170), Expect = 2e-11 Identities = 60/304 (19%), Positives = 145/304 (47%), Gaps = 9/304 (2%) Query: 1643 TQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERT 1702 +++ +R +++ + L+ A + +L+ +E R L EL + + E + Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311 Query: 1703 RRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ----AEVENSIQESRNAEE- 1757 E L A ++ L +Q +L + +E ++ + + AE+ + + E Sbjct: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371 Query: 1758 --KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKK 1814 K ++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKK 1430 Query: 1815 QIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDK 1874 + Q+L +++ + L+ +Q R E K +++ ++ + +A+ + +LQ D Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490 Query: 1875 LQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934 L A+ S K+Q EE + + ++ EL++ + + E+ + K++ + RD+ ++ Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550 Query: 1935 KMEE 1938 ++ Sbjct: 1551 VKDQ 1554 Score = 56.6 bits (135), Expect = 2e-07 Identities = 109/534 (20%), Positives = 222/534 (41%), Gaps = 63/534 (11%) Query: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQA---ELEAAQKESRSLSTELFK 1487 D MR + + + +R FD + +K + E A ++ L E Sbjct: 1103 DAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSS 1162 Query: 1488 MRNAYEEVVDQLETLRRENKNLQEEIS-DLTE-QIAETGKNLQEAEKTKKLVEQEKSDLQ 1545 V + TL R + E+ S +LT Q A G ++ K +K+ + +Q Sbjct: 1163 CCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQ 1222 Query: 1546 VALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVL 1605 +++ +G + K+ L +V+ + ++ KDEEI+QL+ ++A + Sbjct: 1223 KNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIRNKDEEIQQLRSKLEKAEKERN--- 1278 Query: 1606 DAEIRSRNDALRLK-KKMEGDLNEMEIQLGHSNRQM--AETQKHLRTVQGQLKDSQLHLD 1662 E+R +D L + ++ +L + E G S Q+ AET + LR + ++K+ Q D Sbjct: 1279 --ELRLNSDRLESRISELTSELTD-ERNTGESASQLLDAETAERLRA-EKEMKELQTQYD 1334 Query: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722 LK+Q+ ++E +E M+ L + + + DA +L + Sbjct: 1335 A-------LKKQMEVME---------MEVMEARLIRAAEINGEVDDD--DAGGEWRLKYE 1376 Query: 1723 QNTSLIN-TKKKLEADIA-------QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774 + ++ TKK+L+ + Q + ++E + + + E++++A+ + L Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436 Query: 1775 KE-QDTSAHLE-------RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK--LENRVR 1824 E QDT HLE ++K + +L +EA++ L+ K Q +K L Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496 Query: 1825 ELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKR 1884 L+ +L+ + A + E ++++++ Q +D ++ AKVK R Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL-----------AKVKKQLR 1545 Query: 1885 QAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 E + +L LE+A R ++ ++ + +K + +++EE Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 483 bits (1244), Expect = e-136 Identities = 310/925 (33%), Positives = 518/925 (56%), Gaps = 49/925 (5%) Query: 71 TLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130 T+ + +V M+P + ++DMA +T LH +++YNL +RY IYTY G +VNPY+ Sbjct: 48 TITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQ 107 Query: 131 WLP-VYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNT 189 + +Y+P + Y + E PPHIF+I++ Y+ + DNQ ILI+GESGAGKT +T Sbjct: 108 PIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTEST 167 Query: 190 KRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKF 249 K ++++ + I+ + E + +E I++++P++EAFGNAKTV N+NSSRFGKF Sbjct: 168 KLILKFLSVIS---QQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224 Query: 250 IRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNP 309 ++++ G + I YLLEK+RV Q ER+YHIFY +++ + E + +ST P Sbjct: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-P 283 Query: 310 FDFPFVSQ-GEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQ 368 ++ +++Q G V +I D E A+D++ FS EE + +L ++H GN++F Sbjct: 284 ENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF-- 341 Query: 369 KQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGA 428 A+ ++ L+GL+ ++ L + + E + NVQQ +S + Sbjct: 342 -ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDS 400 Query: 429 LAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 488 LA A+Y F W++ +IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ Sbjct: 401 LAMALYACCFEWVIKKINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQ 459 Query: 489 QFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 548 ++FN H+F LEQ EY +EG+ WE ID+ +D C++LIEK +G+ +++ EE FP+ATD+ Sbjct: 460 EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDS 518 Query: 549 SFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVV 608 + KL+ QH +NN KP A +F + HYAG V Y++ G L+KN+D + ++ Sbjct: 519 TLLEKLHSQH---ANNHFYVKPR--VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573 Query: 609 GLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRS 668 L ++S + LF + + D+ K G K + TVS+ F+++L+ LM L S Sbjct: 574 NLLRESRFDFIYDLFEHVSSRNNQDT--LKCGSKHRR---PTVSSQFKDSLHSLMATLSS 628 Query: 669 THPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRI 728 ++P FVRC+ PN K P D +V++QLR +G+LE +RI + G+ R + DF +RY++ Sbjct: 629 SNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKV 688 Query: 729 LNAS-AIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVT 787 L + A+PE D + LL D +++ G TKVF + L LE+ R+E++ Sbjct: 689 LMRNLALPE----DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSH 744 Query: 788 LMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFM---NVKHWPWMNLFF--KIKP 842 +A G+L R +++K++ + IQ N R+F+ H + F +++ Sbjct: 745 AAMVIRAHVLGFLARKQYRKVLY---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801 Query: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902 + + +A +E E+ K+E E +K+ EE+ +E+ + +L+ Q E E Sbjct: 802 QIARRVYRQLLAEKREQEEKKKQE----EEEKKKREEEERERERERREAELRAQQEEET- 856 Query: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962 ++ E L KS+ K ELT LE+++E ++ V + LE + L+R + E Sbjct: 857 -RKQQELEALQKSQ-----KEAELTRELEKQKE--NKQVEEILRLEKEIEDLQRMKEQQE 908 Query: 963 LTLTK--VEKEKHATENKVKNLSEE 985 L+LT+ ++K + + +++ L EE Sbjct: 909 LSLTEASLQKLQERRDQELRRLEEE 933 Score = 52.4 bits (124), Expect = 4e-06 Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 24/192 (12%) Query: 1045 EKKLRADL-ERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFEL--SQLQAKIDDE 1101 +K+LR + R R+L + + +E E +K++ EE+ +++E E ++L+A+ ++E Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855 Query: 1102 -----QVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156 ++ +LQ +K EL +E+ +E + E LR +EK+ DL R E+ L E Sbjct: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQELSLTE 913 Query: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQR 1216 AS + K +E RRD E L+ EA A ++ + E+ E + N++R Sbjct: 914 AS--------LQKLQE------RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959 Query: 1217 VKQKLEKEKSEL 1228 + SEL Sbjct: 960 SLSVGSEFSSEL 971 Score = 47.4 bits (111), Expect = 1e-04 Identities = 56/214 (26%), Positives = 102/214 (47%), Gaps = 33/214 (15%) Query: 1277 LNMQKARLQTQN---GELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333 L+++KA + Q G+++ RV + L+++ + ++ Q+ EE K++ EEE + + Sbjct: 786 LHLKKAAIVFQKQLRGQIARRVYRQ--LLAEKREQEEKKKQEEEE-KKKREEEERER--- 839 Query: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393 + R + + LR Q EEE + EL+ AL K+ E R + ++ EE+ Sbjct: 840 ----ERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRL 893 Query: 1394 KKKL--AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQR 1451 +K++ QR++E +E + T ASL+K ++R E +R LE A + Sbjct: 894 EKEIEDLQRMKEQQELSLTE----ASLQKLQERRDQE----LRRLEEEACRAAQEFLESL 945 Query: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL 1485 NFD++ DE +E + S+EL Sbjct: 946 NFDEI--------DECVRNIERSLSVGSEFSSEL 971 Score = 47.0 bits (110), Expect = 2e-04 Identities = 43/162 (26%), Positives = 83/162 (51%), Gaps = 7/162 (4%) Query: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531 E ++E + E K + EE + E E + QEE + +++ K+ +EAE Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAE 873 Query: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591 T++L E++K + QV E + E E+ + ++ Q ELS ++ L + +D+E+ +L+ Sbjct: 874 LTREL-EKQKENKQVE-EILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLE 931 Query: 1592 RNSQRAA-EALQSV----LDAEIRSRNDALRLKKKMEGDLNE 1628 + RAA E L+S+ +D +R+ +L + + +L E Sbjct: 932 EEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973 Score = 43.9 bits (102), Expect = 0.002 Identities = 47/207 (22%), Positives = 100/207 (48%), Gaps = 32/207 (15%) Query: 939 ELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTK 998 +L+A+KR E+K + + K ++E+ E + + E+ A +E ++ + Sbjct: 810 QLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRAQQEEETRKQQ 860 Query: 999 EKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQE---------KKLR 1049 E ++LQ++ ++ ++E+ K N ++ +LE++ +DL+ EQ+ +KL+ Sbjct: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ 920 Query: 1050 ADLERAKRKLEGD-LKMSQESIMDLENDKQQIEEKLKKKE------FELSQLQAKIDDEQ 1102 ++ R+LE + + +QE + L D +I+E ++ E E S A+ E+ Sbjct: 921 ERRDQELRRLEEEACRAAQEFLESLNFD--EIDECVRNIERSLSVGSEFSSELAESACEE 978 Query: 1103 VHSLQFQKKIKELQARIEELEEEIEAE 1129 + F + E EE++E EA+ Sbjct: 979 KPNFNFSQPYPE-----EEVDEGFEAD 1000 Score = 39.3 bits (90), Expect = 0.038 Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 10/124 (8%) Query: 1820 ENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKV 1879 E R +E + + + E+K+ E + + ER+ E+ Q EE+ R Q ++ LQ Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869 Query: 1880 KSYKRQAEEAEEQANTQLSRCRRVQHELEE-----AAERADIAESQVNKLRAKSRDVGSQ 1934 K + E +++ N Q+ R++ E+E+ + + E+ + KL+ + RD + Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER-RDQELR 928 Query: 1935 KMEE 1938 ++EE Sbjct: 929 RLEE 932 Score = 36.6 bits (83), Expect = 0.24 Identities = 35/153 (22%), Positives = 75/153 (49%), Gaps = 17/153 (11%) Query: 1448 KKQRNFDKVLAEWKQKLDESQ---AELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504 KKQ +K E +++ E + AEL A Q+E EL ++ + +E + L + Sbjct: 822 KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKE-AELTRELEK 880 Query: 1505 ENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILR 1564 + +N Q E+I K +++ ++ K+ +QE S + +L++++ E + ++ R Sbjct: 881 QKENKQ------VEEILRLEKEIEDLQRMKE--QQELSLTEASLQKLQ---ERRDQELRR 929 Query: 1565 VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRA 1597 ++ E + E + +EI++ RN +R+ Sbjct: 930 LEEEACRAAQEFLESL--NFDEIDECVRNIERS 960 Score = 32.3 bits (72), Expect = 4.6 Identities = 30/130 (23%), Positives = 64/130 (49%), Gaps = 17/130 (13%) Query: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562 RR + L E + E+ + + ++ E+ ++ E+E+ + ++ ++ E + + +E + Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE- 863 Query: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622 L+ SQ ++EL R E+E+ K N Q ++ +L E + D R+K++ Sbjct: 864 ---ALQKSQKEAELTR-------ELEKQKENKQ-----VEEILRLE-KEIEDLQRMKEQQ 907 Query: 1623 EGDLNEMEIQ 1632 E L E +Q Sbjct: 908 ELSLTEASLQ 917 Score = 32.0 bits (71), Expect = 6.0 Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 42/162 (25%) Query: 1716 RVQLLHSQNTSLINTKKKLEADIA-----QCQAEV-ENSIQESRNAEEKAKKAITD---- 1765 R + LH + +++ +K+L IA Q AE E ++ + EEK K+ + Sbjct: 782 RRRFLHLKKAAIV-FQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840 Query: 1766 --------AAMMAEELKKEQDTSA------------HLERMKKN--------LEQTVKDL 1797 A EE +K+Q+ A LE+ K+N LE+ ++DL Sbjct: 841 RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900 Query: 1798 QHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAE 1839 Q R+ E ++L+L + +QKL+ R + L+ E R A+ Sbjct: 901 Q-RMKEQQELSLT--EASLQKLQERRDQELRRLEEEACRAAQ 939 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 474 bits (1220), Expect = e-133 Identities = 335/1042 (32%), Positives = 528/1042 (50%), Gaps = 102/1042 (9%) Query: 73 NNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWL 132 N + PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L Sbjct: 52 NATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL 111 Query: 133 PVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRV 192 +Y PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK + Sbjct: 112 SIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLI 171 Query: 193 IQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRI 252 +Q+ A I+ +E Q+++A P+LEAFGNAKT+RNDNSSRFGK+I I Sbjct: 172 LQFLAAIS------------GQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDI 219 Query: 253 HFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDF 312 HF G + A IE YLLEKSRV Q ER+YH+FY ++ + L + D+ Sbjct: 220 HFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDY 278 Query: 313 PFVSQGE-VTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQR 371 +++ G +T DS+E +A+ +L F+ E I KL A++H GN++++ + Sbjct: 279 NYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTF 338 Query: 372 E--EQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGAL 429 E + E + A L+ +N +++ L + E V+ + +Q + A Sbjct: 339 ENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAF 398 Query: 430 AKAVYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 483 K +Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457 Query: 484 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 543 NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517 Query: 544 KATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPL 603 K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573 Query: 604 NETVVGLYQKSSLKLLSFLFSN--YAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNK 661 + ++ L S K + +F GAET +K+ T+S+ F+ +L Sbjct: 574 HGDIIQLVHSSRNKFIKQIFQADVAMGAET----------RKRS---PTLSSQFKRSLEL 620 Query: 662 LMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYAD 721 LM L + P FVRC+ PNE K P + D +L + QLR +G++E IRI R G+P R + + Sbjct: 621 LMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVE 680 Query: 722 FKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMR 781 F +RYR+L P + D + +++ ++ + ++ G TK+F K LLE R Sbjct: 681 FVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVER 740 Query: 782 DEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNL-FFKI 840 D+ + + Q V RG+ R F K+ +++ IQ + R K++ M L F ++ Sbjct: 741 DKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797 Query: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 + L +S + ++ ++ + + R+ RK ++ ++ L VQ+ Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYAR 848 Query: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKK------RNLEDKCSSL 954 ++ R ++++ L + +++ RL EEE++ E+ AKK R +++ + L Sbjct: 849 GMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904 Query: 955 KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDL 1014 R+ + EL KEK A K + L + A E ++ H + Sbjct: 905 AREDAEREL------KEKEAARRKKELLEQMERARHEPVN------------HSDMV--- 943 Query: 1015 QVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL-EGDLKMSQESIMDL 1073 DK+ G + + L Q E DLER +R++ E DL ++ + L Sbjct: 944 ----DKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRREMVEEDL----DAALPL 988 Query: 1074 ENDKQQIEEKLKKKEFELSQLQ 1095 ++ ++ + K +F + Q Sbjct: 989 PDEDEEDLSEYKFAKFAATYFQ 1010 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 474 bits (1220), Expect = e-133 Identities = 335/1042 (32%), Positives = 528/1042 (50%), Gaps = 102/1042 (9%) Query: 73 NNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWL 132 N + PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L Sbjct: 52 NATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL 111 Query: 133 PVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRV 192 +Y PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK + Sbjct: 112 SIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLI 171 Query: 193 IQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRI 252 +Q+ A I+ +E Q+++A P+LEAFGNAKT+RNDNSSRFGK+I I Sbjct: 172 LQFLAAIS------------GQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDI 219 Query: 253 HFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDF 312 HF G + A IE YLLEKSRV Q ER+YH+FY ++ + L + D+ Sbjct: 220 HFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDY 278 Query: 313 PFVSQGE-VTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQR 371 +++ G +T DS+E +A+ +L F+ E I KL A++H GN++++ + Sbjct: 279 NYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTF 338 Query: 372 E--EQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGAL 429 E + E + A L+ +N +++ L + E V+ + +Q + A Sbjct: 339 ENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAF 398 Query: 430 AKAVYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 483 K +Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457 Query: 484 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 543 NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517 Query: 544 KATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPL 603 K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573 Query: 604 NETVVGLYQKSSLKLLSFLFSN--YAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNK 661 + ++ L S K + +F GAET +K+ T+S+ F+ +L Sbjct: 574 HGDIIQLVHSSRNKFIKQIFQADVAMGAET----------RKRS---PTLSSQFKRSLEL 620 Query: 662 LMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYAD 721 LM L + P FVRC+ PNE K P + D +L + QLR +G++E IRI R G+P R + + Sbjct: 621 LMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVE 680 Query: 722 FKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMR 781 F +RYR+L P + D + +++ ++ + ++ G TK+F K LLE R Sbjct: 681 FVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVER 740 Query: 782 DEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNL-FFKI 840 D+ + + Q V RG+ R F K+ +++ IQ + R K++ M L F ++ Sbjct: 741 DKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797 Query: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 + L +S + ++ ++ + + R+ RK ++ ++ L VQ+ Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYAR 848 Query: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKK------RNLEDKCSSL 954 ++ R ++++ L + +++ RL EEE++ E+ AKK R +++ + L Sbjct: 849 GMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904 Query: 955 KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDL 1014 R+ + EL KEK A K + L + A E ++ H + Sbjct: 905 AREDAEREL------KEKEAARRKKELLEQMERARHEPVN------------HSDMV--- 943 Query: 1015 QVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL-EGDLKMSQESIMDL 1073 DK+ G + + L Q E DLER +R++ E DL ++ + L Sbjct: 944 ----DKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRREMVEEDL----DAALPL 988 Query: 1074 ENDKQQIEEKLKKKEFELSQLQ 1095 ++ ++ + K +F + Q Sbjct: 989 PDEDEEDLSEYKFAKFAATYFQ 1010 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 474 bits (1220), Expect = e-133 Identities = 335/1042 (32%), Positives = 528/1042 (50%), Gaps = 102/1042 (9%) Query: 73 NNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWL 132 N + PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L Sbjct: 52 NATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL 111 Query: 133 PVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRV 192 +Y PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK + Sbjct: 112 SIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLI 171 Query: 193 IQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRI 252 +Q+ A I+ +E Q+++A P+LEAFGNAKT+RNDNSSRFGK+I I Sbjct: 172 LQFLAAIS------------GQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDI 219 Query: 253 HFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDF 312 HF G + A IE YLLEKSRV Q ER+YH+FY ++ + L + D+ Sbjct: 220 HFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDY 278 Query: 313 PFVSQGE-VTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQR 371 +++ G +T DS+E +A+ +L F+ E I KL A++H GN++++ + Sbjct: 279 NYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTF 338 Query: 372 E--EQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGAL 429 E + E + A L+ +N +++ L + E V+ + +Q + A Sbjct: 339 ENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAF 398 Query: 430 AKAVYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 483 K +Y ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457 Query: 484 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 543 NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517 Query: 544 KATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPL 603 K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573 Query: 604 NETVVGLYQKSSLKLLSFLFSN--YAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNK 661 + ++ L S K + +F GAET +K+ T+S+ F+ +L Sbjct: 574 HGDIIQLVHSSRNKFIKQIFQADVAMGAET----------RKRS---PTLSSQFKRSLEL 620 Query: 662 LMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYAD 721 LM L + P FVRC+ PNE K P + D +L + QLR +G++E IRI R G+P R + + Sbjct: 621 LMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVE 680 Query: 722 FKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMR 781 F +RYR+L P + D + +++ ++ + ++ G TK+F K LLE R Sbjct: 681 FVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVER 740 Query: 782 DEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNL-FFKI 840 D+ + + Q V RG+ R F K+ +++ IQ + R K++ M L F ++ Sbjct: 741 DKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797 Query: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900 + L +S + ++ ++ + + R+ RK ++ ++ L VQ+ Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYAR 848 Query: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKK------RNLEDKCSSL 954 ++ R ++++ L + +++ RL EEE++ E+ AKK R +++ + L Sbjct: 849 GMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904 Query: 955 KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDL 1014 R+ + EL KEK A K + L + A E ++ H + Sbjct: 905 AREDAEREL------KEKEAARRKKELLEQMERARHEPVN------------HSDMV--- 943 Query: 1015 QVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL-EGDLKMSQESIMDL 1073 DK+ G + + L Q E DLER +R++ E DL ++ + L Sbjct: 944 ----DKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRREMVEEDL----DAALPL 988 Query: 1074 ENDKQQIEEKLKKKEFELSQLQ 1095 ++ ++ + K +F + Q Sbjct: 989 PDEDEEDLSEYKFAKFAATYFQ 1010 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.340 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,955,122 Number of Sequences: 37866 Number of extensions: 2935253 Number of successful extensions: 63210 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 829 Number of HSP's successfully gapped in prelim test: 1632 Number of HSP's that attempted gapping in prelim test: 13529 Number of HSP's gapped (non-prelim): 16276 length of query: 1938 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1821 effective length of database: 13,817,196 effective search space: 25161113916 effective search space used: 25161113916 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.