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Search of human proteins with 110611903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
(1939 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3757 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3577 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3498 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3498 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3450 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3196 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 3141 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3115 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 3107 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2576 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2315 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1424 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1424 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1422 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1422 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1402 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1396 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1285 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1285 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1276 0.0
gi|153945715 myosin VC [Homo sapiens] 595 e-169
gi|215982791 myosin VA isoform 1 [Homo sapiens] 590 e-168
gi|215982794 myosin VA isoform 2 [Homo sapiens] 590 e-168
gi|122937345 myosin VB [Homo sapiens] 569 e-161
gi|42794779 myosin 18A isoform b [Homo sapiens] 501 e-141
gi|28416946 myosin 18A isoform a [Homo sapiens] 501 e-141
gi|154354979 myosin X [Homo sapiens] 482 e-135
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 473 e-133
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 473 e-133
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 473 e-133
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 3757 bits (9743), Expect = 0.0
Identities = 1939/1939 (100%), Positives = 1939/1939 (100%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM
Sbjct: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
Query: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA
Sbjct: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM
Sbjct: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
Query: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI
Sbjct: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
Query: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
Query: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
Query: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR
Sbjct: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
Query: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
Query: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK
Sbjct: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
Query: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE
Sbjct: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
Query: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
Query: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE
Sbjct: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
Query: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
Query: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK
Sbjct: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
Query: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
Query: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ
Sbjct: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
Query: 1921 VNKLRVKSREVHTKVISEE 1939
VNKLRVKSREVHTKVISEE
Sbjct: 1921 VNKLRVKSREVHTKVISEE 1939
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 3577 bits (9276), Expect = 0.0
Identities = 1824/1939 (94%), Positives = 1892/1939 (97%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSDSEMAIFGEAAPFLRKSE+ERIEAQNKPFDAKTSVFVVDPKES+VKA VQSREGGKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
TAKTEAGATVTVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYN EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE SGKMQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI+SNKKP+L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
IEMLLITTNPYD+AFVSQGEITVPSIDDQEELMATDSA++ILGFT+DE+V+IYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKAAYL +LNSADLLK+LCYPRVKVGNE+VTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQVYNAVGALAKA+Y+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSL+HYAGTVDYNIAGWLDKN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
KDPLNETVVGLYQKSAMKTLA LF GA AEAE GGGKKGGKKKGSSFQTVSALFRENLN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN 660
Query: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA
Sbjct: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSI+IDHTQYKFGHTKVFFKAGLLG LEEM
Sbjct: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM 780
Query: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
RDEKLAQLITRTQA+CRGFL RVE++KM+ERRESIFCIQYN+RAFMNVKHWPWMKLYFKI
Sbjct: 781 RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI 840
Query: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
+LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EEDK
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
VNTLTKAK KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKLAQESTMD ENDKQQL
Sbjct: 1021 VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL 1080
Query: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+EKLKKKEFEMS LQ KIEDEQAL +QLQKKIKELQARIEELEEEIEAERASRAKAEKQR
Sbjct: 1081 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRKKH
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1200
Query: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
ADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASNMETVSKAK N EKMCR LEDQL
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL 1260
Query: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
SEIKTKEEEQQRLIN+L+AQ+ARL TESGE+SRQLDEKD +VSQLSRGKQAFTQQIEELK
Sbjct: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
Query: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
RQLEEE KAKS LAHALQS+RHDCDLLREQYEEEQEAKAELQR MSKANSEVAQWRTKYE
Sbjct: 1321 RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE 1380
Query: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN+KCASLEKTKQRLQNEVEDLMIDVER+N
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN 1440
Query: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
AAC ALDKKQRNFDK+LAEWKQK EET AELEASQKESRSLSTELFK+KNAYEESLD LE
Sbjct: 1441 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE 1500
Query: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
TLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EKSELQ +LEEAEASLEHEEG
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG 1560
Query: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
KILRIQLELNQVKSE+DRKIAEKDEE+DQ+KRNH+R+VESMQSTLDAEIRSRNDA+R+KK
Sbjct: 1561 KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1620
Query: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
KMEGDLNEMEIQLNHANR AAEALRN RNTQ ILKDTQLHLDDA+R Q+DLKEQLAMVER
Sbjct: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680
Query: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
RANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDISQ
Sbjct: 1681 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
IQGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ R
Sbjct: 1741 IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
Query: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
LDEAEQLALKGGKKQIQKLEARVRELE EVESEQK NVEAVKGLRKHER+VKELTYQTEE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE 1860
Query: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
DRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSNVNL+KFR++QHELEEA+ERADIAESQ
Sbjct: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ 1920
Query: 1921 VNKLRVKSREVHTKVISEE 1939
VNKLRVKSREVHTK+ISEE
Sbjct: 1921 VNKLRVKSREVHTKIISEE 1939
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3498 bits (9070), Expect = 0.0
Identities = 1783/1941 (91%), Positives = 1870/1941 (96%), Gaps = 2/1941 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSDSE+A+FGEAAPFLRKSE+ERIEAQN+PFDAKTSVFV +PKES+VK +QSREGGKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T KTE GAT+TVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE SGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
IEMLLITTNPYD+ FVSQGEI+V SIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGN+KFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
+QV NAVGALAKA+YEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+L+HYAG VDYNI GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGG--KKGGKKKGSSFQTVSALFREN 658
KDPLNETVVGLYQKSAMKTLA LFSGAQTAE EG GG KKGGKKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718
LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLE 778
YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 779 EMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYF 838
EMRD+KLAQLITRTQA CRGFL RVE+++M+ERRE+IFCIQYNIR+FMNVKHWPWMKL+F
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078
DKVNTLTKAK KLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQES MD EN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
QL+EKLKKKEFE+SNLQ KIEDEQAL IQLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198
QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1199 KHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLED 1258
KHADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASN+ETVSKAK N EKMCRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1259 QLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318
QLSE+K+KEEEQQRLIN+L+AQ+ RL TESGEFSRQLDEK+A+VSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
LKRQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE+KAELQR +SKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498
+NAAC ALDKKQRNFDK+LAEWKQK EET AELEASQKE+RSL TELFK+KNAYEESLD
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE 1558
LETLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK ELQ +LEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1559 EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618
EGKILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH+R+VESMQSTLDAEIRSRNDA+R+
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678
KKKMEGDLNEMEIQLNHANR AAEALRN RNTQGILKDTQ+HLDDA+R Q+DLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
ERRANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798
SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT 1858
LRLDEAEQLALKGGKKQIQKLEARVRELE EVESEQK N EAVKGLRKHERRVKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1859 EEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918
EEDRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSN NLAKFRKLQHELEEA+ERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1919 SQVNKLRVKSREVHTKVISEE 1939
SQVNKLRVKSREVHTKVISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3498 bits (9070), Expect = 0.0
Identities = 1783/1941 (91%), Positives = 1870/1941 (96%), Gaps = 2/1941 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSDSE+A+FGEAAPFLRKSE+ERIEAQN+PFDAKTSVFV +PKES+VK +QSREGGKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T KTE GAT+TVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTGEKKKEE SGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
IEMLLITTNPYD+ FVSQGEI+V SIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGN+KFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
+QV NAVGALAKA+YEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+L+HYAG VDYNI GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGG--KKGGKKKGSSFQTVSALFREN 658
KDPLNETVVGLYQKSAMKTLA LFSGAQTAE EG GG KKGGKKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718
LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLE 778
YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 779 EMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYF 838
EMRD+KLAQLITRTQA CRGFL RVE+++M+ERRE+IFCIQYNIR+FMNVKHWPWMKL+F
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078
DKVNTLTKAK KLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQES MD EN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
QL+EKLKKKEFE+SNLQ KIEDEQAL IQLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198
QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1199 KHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLED 1258
KHADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASN+ETVSKAK N EKMCRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1259 QLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318
QLSE+K+KEEEQQRLIN+L+AQ+ RL TESGEFSRQLDEK+A+VSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
LKRQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE+KAELQR +SKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498
+NAAC ALDKKQRNFDK+LAEWKQK EET AELEASQKE+RSL TELFK+KNAYEESLD
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE 1558
LETLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK ELQ +LEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1559 EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618
EGKILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH+R+VESMQSTLDAEIRSRNDA+R+
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678
KKKMEGDLNEMEIQLNHANR AAEALRN RNTQGILKDTQ+HLDDA+R Q+DLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
ERRANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798
SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT 1858
LRLDEAEQLALKGGKKQIQKLEARVRELE EVESEQK N EAVKGLRKHERRVKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1859 EEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918
EEDRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSN NLAKFRKLQHELEEA+ERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1919 SQVNKLRVKSREVHTKVISEE 1939
SQVNKLRVKSREVHTKVISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 3450 bits (8945), Expect = 0.0
Identities = 1750/1937 (90%), Positives = 1859/1937 (95%), Gaps = 3/1937 (0%)
Query: 2 SSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVT 61
SSD+EMA+FGEAAP+LRKSEKERIEAQNKPFDAKTSVFV +PKESYVK+ +QS+EGGKVT
Sbjct: 4 SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
Query: 62 AKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121
KTE GAT+TV+EDQVF MNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 64 VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
Query: 122 FCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181
FCVTVNPYKWLPVY PEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 124 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
Query: 182 GAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
GAGKTVNTKRVIQYFATIAVTGEKKK+E SGKMQGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 184 GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
Query: 242 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELI 301
DNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKP+LI
Sbjct: 242 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
Query: 302 EMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMH 361
EMLLITTNPYD+AFVSQGEITVPSIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVMH
Sbjct: 302 EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
Query: 362 YGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQ 421
YGNMKFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTVQ
Sbjct: 362 YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
Query: 422 QVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
QVYNAVGALAKA+YEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422 QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
Query: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 541
NFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
Query: 542 MFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNK 601
MFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHFSL+HYAGTVDYNI GWLDKNK
Sbjct: 542 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
Query: 602 DPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNK 661
DPLN+TVVGLYQKSAMKTLA LFS +AEA+ KKG KKKGSSFQTVSALFRENLNK
Sbjct: 602 DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSA-KKGAKKKGSSFQTVSALFRENLNK 660
Query: 662 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 721
LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY D
Sbjct: 661 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
Query: 722 FKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMR 781
FKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LEEMR
Sbjct: 721 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
Query: 782 DEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIK 841
DEKLAQ+ITRTQA+CRGFLMRVE++KM++RRE++FCIQYN+RAFMNVKHWPWMKL+FKIK
Sbjct: 781 DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
Query: 842 PLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADA 901
PLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQ+EAD+
Sbjct: 841 PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
Query: 902 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961
LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDL
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
Query: 962 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKV 1021
ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQ EEDKV
Sbjct: 961 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 1022 NTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLN 1081
N LTKAKTKLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQESTMD ENDKQQL+
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
EKL+KKEFE+SNL KIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQRS
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHA 1201
DLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEE+TLQHEA AALRKKHA
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
Query: 1202 DSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLS 1261
DS+AELGEQID+LQRVKQKLEKEKSELKME +DL+SN E +SKAK N EKMCR+LEDQ+S
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
Query: 1262 EIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKR 1321
E+KTKEEEQQRLIN+L+AQ+ARL TE+GE+SRQLDEKDA+VSQLSR KQA TQQIEELK
Sbjct: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
Query: 1322 QLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYET 1381
QLEEETKAK+ LAHALQS+RHDCDLLREQYEEEQE KAELQR +SKANSEVAQWRTKYET
Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
Query: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNA 1441
DAIQRTEELEEAKKKLAQRLQ+AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVERSNA
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
Query: 1442 ACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLET 1501
AC ALDKKQRNFDKVL+EWKQKYEETQAELEASQKESRSLSTELFKVKN YEESLD LET
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
Query: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGK 1561
L+RENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK E+Q +LEEAEASLEHEEGK
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 1562 ILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKK 1621
ILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH RVVE+MQSTLDAEIRSRNDALR+KKK
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
Query: 1622 MEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERR 1681
MEGDLNEMEIQLNHANR AAE+LRN RNTQGILK+TQLHLDDA+RGQ+DLKEQLA+VERR
Sbjct: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
Query: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQI 1741
ANL+QAE+EEL A+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLE D+SQ+
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
Query: 1742 QGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801
Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ RL
Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Query: 1802 DEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED 1861
DEAEQLALKGGKKQIQKLEARVRELE EVE+EQK N EAVKGLRKHERRVKELTYQTEED
Sbjct: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
Query: 1862 RKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV 1921
RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQSN NL+KFRKLQHELEEA+ERADIAESQV
Sbjct: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
Query: 1922 NKLRVKSREVHTKVISE 1938
NKLRVKSREVHTK+ +E
Sbjct: 1921 NKLRVKSREVHTKISAE 1937
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 3196 bits (8286), Expect = 0.0
Identities = 1611/1930 (83%), Positives = 1788/1930 (92%), Gaps = 3/1930 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSD+EM +FG AAPFLRKSEKERIEAQN+PFDAKT FVVD KE Y K ++S + GKV
Sbjct: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
T +TE T+ VK + V++MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYNPEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIA TG+ K++ + KM+GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKKDS--KMKGTLEDQIISANPLLEAFGNAKTVR 238
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL
Sbjct: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
IE+LLITTNPYD+ F+SQGEI V SIDD EEL+ATDSA+DILGFT +EK +YKLTGAVM
Sbjct: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADK AYL LNS+DLLK+LC+PRVKVGNE+VTKGQTV
Sbjct: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QV++AV AL+K++YEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKSNNFQKPK KG+ EAHFSL+HYAGTVDY+++GWL+KN
Sbjct: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
KDPLNETVVGLYQKS+ + LA L++ TA+A+ G KK KKKGSSFQTVSALFRENLN
Sbjct: 599 KDPLNETVVGLYQKSSNRLLAHLYATFATADADSGK-KKVAKKKGSSFQTVSALFRENLN 657
Query: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
KLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 658 KLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYG 717
Query: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
DFKQRY+VLNASAIPEGQFIDSKKA EKLL SI+IDHTQYKFGHTKVFFKAGLLGTLEEM
Sbjct: 718 DFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEM 777
Query: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
RD++LA+LITRTQA+CRGFLMRVEF+KM++RRESIFCIQYNIR+FMNVKHWPWMKL+FKI
Sbjct: 778 RDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKI 837
Query: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
KPLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEK+VTL+QEKNDLQLQVQAE++
Sbjct: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897
Query: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
Query: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
LELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQ EEDK
Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
VN+L K K+KLEQQV+DLE SLEQEKKL +DLER KRKLEGDLKLAQES +D ENDKQQL
Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077
Query: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
+E+LKKK+FE LQ K+EDEQ L +Q QKKIKELQARIEELEEEIEAERA+RAK EKQR
Sbjct: 1078 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
SD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEE+TLQHEA AALRKKH
Sbjct: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
Query: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
ADSVAELGEQID+LQRVKQKLEKEKSE K+EI+DL+S+ME+VSK+KAN EK+CRTLEDQL
Sbjct: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
Query: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
SE + K EE QR ++EL+ QK+RL TE+GE SRQL+EK+++VSQLSR KQAFTQQ EELK
Sbjct: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317
Query: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
RQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE KAELQR +SKANSEVAQWRTKYE
Sbjct: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377
Query: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
TDAIQRTEELEEAKKKLAQRLQD+EE VEAVN+KCASLEKTKQRLQ EVEDLM+DVER+N
Sbjct: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Query: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
+ ALDKKQRNFDKVLAEWK K EE+QAELEAS KESRSLSTELFK+KNAYEE+LD LE
Sbjct: 1438 SLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLE 1497
Query: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
T+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ++ EK+++Q +LEEAEA+LEHEE
Sbjct: 1498 TVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEA 1557
Query: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
KILRIQLEL QVKSEIDRKIAEKDEE++QLKRN+ R VE+MQS LDAE+RSRN+A+R+KK
Sbjct: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 1617
Query: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
KMEGDLNE+EIQL+HANRQAAE L++LR+ QG LKDTQLHLDDA+RGQ+DLKEQLA+VER
Sbjct: 1618 KMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVER 1677
Query: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
RANL+QAEVEELRA+LE+TER RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+ Q
Sbjct: 1678 RANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ 1737
Query: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ R
Sbjct: 1738 LQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1797
Query: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
LDEAEQLALKGGKKQIQKLE R+RELE E+E EQK N E+VKGLRK+ERRVKELTYQ+EE
Sbjct: 1798 LDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857
Query: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
DRKN+LRLQDLVDKLQ KVK+YKRQAEEA+EQ+N +L KFRK QHELEEA+ERADIAESQ
Sbjct: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917
Query: 1921 VNKLRVKSRE 1930
VNKLR K+R+
Sbjct: 1918 VNKLRAKTRD 1927
Score = 216 bits (550), Expect = 2e-55
Identities = 210/950 (22%), Positives = 419/950 (44%), Gaps = 82/950 (8%)
Query: 994 AKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLE 1053
A+ KE ++E Q+T D+L E K L + L Q+ +DL+ ++ E + +D E
Sbjct: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
Query: 1054 RAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIK 1113
++ ++ +K K QL+ KIK
Sbjct: 904 ------------------------ERCDQLIKAK------------------FQLEAKIK 921
Query: 1114 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1172
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
Query: 1173 AEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQK---LEKEKSELK 1229
A K++ EE + E A R+K A A + +D LQ + K L K KS+L+
Sbjct: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
Query: 1230 MEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG 1289
++ DL S++E K + + E+ R LE ++K +E L N+ RL +
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
Query: 1290 EFSR---QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDL 1346
E+ + +++++ + Q + + +IEEL+ ++E E ++ + +
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
Query: 1347 LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
L E+ EE + K +E + R E +Q + +KK A + + E
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGE 1206
Query: 1407 HVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEE 1466
++ + LEK K + E++DL +E + + L+K R + L+E + K EE
Sbjct: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266
Query: 1467 TQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKH 1526
Q L + L TE ++ EE + L R + Q+ +L Q+ E K
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Query: 1527 IHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
+ L + H+ L+ EE + + + + E+ Q +++ + ++ EE
Sbjct: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1386
Query: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
L++ K+ + ++ + ++A + K++++G++ ++ + + AN AA +
Sbjct: 1387 LEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKK 1446
Query: 1647 LRNTQGILKDTQLHLDDA-IRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKM 1705
RN +L + + +++ + LKE ++ L A EE LE +R K
Sbjct: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEEALDQLETVKRENKN 1505
Query: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITD 1765
EQE+ D +E++ L ++K++E + + IQ +E+ + E K + +
Sbjct: 1506 LEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 1565
Query: 1766 AAMMAEEL-KKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVR 1824
+ E+ +K + +E++K+N ++TV+ +Q LD AE + + +K+E +
Sbjct: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRNEAIRLKKKMEGDLN 1624
Query: 1825 ELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKR 1884
E+E ++ + E +K LR + ++K+ T+ + LR Q+ + K
Sbjct: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKD----TQLHLDDALRGQEDL----------KE 1670
Query: 1885 QAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTK 1934
Q E ++N+ A+ +L+ LE+ + +AE ++ + + +HT+
Sbjct: 1671 QLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQ 1720
Score = 85.1 bits (209), Expect = 6e-16
Identities = 86/346 (24%), Positives = 152/346 (43%), Gaps = 48/346 (13%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
++AET K + +++ + + T+ L +++L+E++ + + N LQ +V+ E A +
Sbjct: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
ER +L E ++ + ER + N L K+KLE + +L+ +++D
Sbjct: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L
Sbjct: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804
Query: 1025 T-----KAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQ 1079
K KLE ++ +LE LE E+K + + RK E +K E T +E D++
Sbjct: 1805 ALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK---ELTYQSEEDRKN 1861
Query: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
+ Q L +LQ K+K + + EE +E+ A KA+
Sbjct: 1862 VLRL------------------QDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ-- 1901
Query: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEES 1185
ELEE ER + A +Q+ + + +F R + ES
Sbjct: 1902 -----HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/195 (23%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTV-------KDLQLRLDEAEQLALK 1810
K+ + + A M EE +K +D A E +K +E+ + DLQL++ + L
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 1811 GGKKQIQ------KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKN 1864
++ Q +LEA+++E+ E E++ N E RK E EL ++
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 1865 ILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERA----DIAESQ 1920
+ +++ + KVK + +E +AK + + L+EA ++A E +
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDE----TIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 1921 VNKLRVKSREVHTKV 1935
VN L ++ +V
Sbjct: 1018 VNSLNKTKSKLEQQV 1032
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 3141 bits (8143), Expect = 0.0
Identities = 1577/1939 (81%), Positives = 1763/1939 (90%), Gaps = 2/1939 (0%)
Query: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
MSSD+EMAIFGEAAP+LRK EKERIEAQN+PFD+K + FV D KE YVK ++Q+RE KV
Sbjct: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60
Query: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
KT +T+ DQVF MNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
SGAGKTVNTKRVIQYFATIAVTG+KKKE GKMQGTLEDQII ANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQP-GKMQGTLEDQIIQANPLLEAFGNAKTVR 239
Query: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI+SNKKPEL
Sbjct: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299
Query: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
I++LLI+TNP+DF FVSQGE+TV SIDD EEL+ATD+A+DILGF+++EKV IYKLTGAVM
Sbjct: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359
Query: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
HYGNMKFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNE+VTKGQ V
Sbjct: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419
Query: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
QQV N+VGALAKA+YEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479
Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539
Query: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
CMFPKATDTSFKNKLY+QHLGKSNNFQKPKPAKGK EAHFSLVHYAGTVDYNIAGWLDKN
Sbjct: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599
Query: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEA-EGGGGKKGGKKKGSSFQTVSALFRENL 659
KDPLNETVVGLYQKS++K L+FLFS AE + GG KKGGKKKGSSFQTVSA+FRENL
Sbjct: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENL 659
Query: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719
NKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY
Sbjct: 660 NKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILY 719
Query: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEE 779
ADFKQRY++LNASAIPEGQFIDSK ASEKLL SI++D Q++FG+TKVFFKAGLLG LEE
Sbjct: 720 ADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEE 779
Query: 780 MRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFK 839
MRDEKL L+T TQA+CRG+LMRVEF+KMMERR+SIFCIQYNIR+FMNVKHWPWM L+FK
Sbjct: 780 MRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFK 839
Query: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
IKPLLKSAE EKEMA MKE+FE+TKEELA++EA+RKELEEKMV+L+QEKNDLQLQVQ+E
Sbjct: 840 IKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSET 899
Query: 900 DALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
+ L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DID
Sbjct: 900 ENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959
Query: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED 1019
DLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ+EED
Sbjct: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019
Query: 1020 KVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQ 1079
KVN L K KLEQQ DDLEGSLEQEKKL DLERAKRKLEGDLK++QES MD ENDKQQ
Sbjct: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079
Query: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
+ EKLKKKEFE+S LQ KI+DEQ ++Q QKKIKELQARIEELEEEIEAE RAK EKQ
Sbjct: 1080 IEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139
Query: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKK 1199
RSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRKK
Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
Query: 1200 HADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQ 1259
ADSVAELGEQID+LQRVKQKLEKEKSELKMEI+D+ASN+E +SK+K+N E+ CRT+EDQ
Sbjct: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259
Query: 1260 LSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEEL 1319
SEIK K+E+Q +LI++L+ QKARL T++GE S +++EK++++SQL++ KQA TQQ+EEL
Sbjct: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEEL 1319
Query: 1320 KRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKY 1379
KRQ+EEETKAK+ +AHALQS+RHDCDLLREQYEEEQEAKAELQR +SKANSEVAQWRTKY
Sbjct: 1320 KRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKY 1379
Query: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERS 1439
ETDAIQRTEELEEAKKKLAQRLQ+AEE+ E NSKCASLEKTKQRLQ EVEDLM D+ERS
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439
Query: 1440 NAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHL 1499
+ AC LDKKQRNFDKVLAEWKQK +E+QAELEA+QKESRSLSTELFK++NAYEE +D L
Sbjct: 1440 HTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQL 1499
Query: 1500 ETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEE 1559
ETL+RENKNLQ+EISDLTEQIAE GK++ E EK KK ++ EKS+LQ +LEE E SLEHEE
Sbjct: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559
Query: 1560 GKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIK 1619
KILR+QLEL+QVKSE+DRK+ EKDEE++QLKRN R E++QS LDAEIRSRNDALR+K
Sbjct: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619
Query: 1620 KKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVE 1679
KKMEGDLNEMEIQL H+NRQ AE ++LR QG LKD+QLHLDDA+R +DLKEQLA+VE
Sbjct: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679
Query: 1680 RRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
RR L+ E+EE++ +LE+TER R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI+
Sbjct: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739
Query: 1740 QIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1799
Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 1800 RLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTE 1859
RLDEAEQLALKGGKKQIQKLE RVRELE+E++ EQK EA+KG K+ER+VKE+TYQ E
Sbjct: 1800 RLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAE 1859
Query: 1860 EDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAES 1919
ED KNILRLQDLVDKLQ KVK+YKRQAEEAEEQ+N L++ R++QHELEEA ERADIAES
Sbjct: 1860 EDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAES 1919
Query: 1920 QVNKLRVKSREVHTKVISE 1938
QVNKLR KSR+V ++ + E
Sbjct: 1920 QVNKLRAKSRDVGSQKMEE 1938
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 3115 bits (8077), Expect = 0.0
Identities = 1564/1936 (80%), Positives = 1757/1936 (90%), Gaps = 3/1936 (0%)
Query: 4 DSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAK 63
DSEMA+FG AAP+LRKSEKER+EAQ +PFD K VFV D K+ +VKA + SREGGKVTA+
Sbjct: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
Query: 64 TEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
TE G TVTVKEDQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
Query: 124 VTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
Query: 184 GKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240
Query: 244 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEM 303
SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQLKAER YHIFYQILSNKKPEL++M
Sbjct: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300
Query: 304 LLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYG 363
LLIT NPYD+AF+SQGE TV SIDD EELMATD+A D+LGFT++EK ++YKLTGA+MH+G
Sbjct: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360
Query: 364 NMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQV 423
NMKFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNE+VTKGQ VQQV
Sbjct: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420
Query: 424 YNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
A GALAKA+YE+MF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480
Query: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540
Query: 544 PKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDP 603
PKATD +FK KL++ HLGKS NFQKP+ KGKPEAHFSL+HYAG VDYNI GWL KNKDP
Sbjct: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600
Query: 604 LNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLM 663
LNETVVGLYQKS++K L+ LF+ A+A GK G KKGSSFQTVSAL RENLNKLM
Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGK-GKAKKGSSFQTVSALHRENLNKLM 659
Query: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
TNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF+
Sbjct: 660 TNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 719
Query: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDE 783
QRY++LN +AIPEGQFIDS+K +EKLL S++IDH QYKFGHTKVFFKAGLLG LEEMRDE
Sbjct: 720 QRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 779
Query: 784 KLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPL 843
+L+++ITR QA RG L R+E++K++ERR+S+ IQ+NIRAFM VK+WPWMKLYFKIKPL
Sbjct: 780 RLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPL 839
Query: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA 903
LKSAE EKEMA+MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D LA
Sbjct: 840 LKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLA 899
Query: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLEL
Sbjct: 900 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLEL 959
Query: 964 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNT 1023
TLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDKVNT
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 1024 LTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEK 1083
LTKAK KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKL QES MD ENDKQQL+E+
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 1084 LKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
LKKK+FE++ L +IEDEQAL QLQKK+KELQARIEELEEE+EAER +RAK EK RSDL
Sbjct: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADS 1203
SRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEE+TLQHEATAAALRKKHADS
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
VAELGEQID+LQRVKQKLEKEKSE K+E++D+ SNME + KAKAN EKMCRTLEDQ++E
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
++K EE QR +N+L++Q+A+L TE+GE SRQLDEK+A++SQL+RGK +TQQ+E+LKRQL
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
EEE KAK+ LAHALQSARHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETDA
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAAC 1443
IQRTEELEEAKKKLAQRLQ+AEE VEAVN+KC+SLEKTK RLQNE+EDLM+DVERSNAA
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439
Query: 1444 IALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLK 1503
ALDKKQRNFDK+LAEWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KNAYEESL+HLET K
Sbjct: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
Query: 1504 RENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKIL 1563
RENKNLQ+EISDLTEQ+ GK IHELEKV+KQL+ EK ELQ++LEEAEASLEHEEGKIL
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559
Query: 1564 RIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKME 1623
R QLE NQ+K+EI+RK+AEKDEE++Q KRNHLRVV+S+Q++LDAE RSRN+ALR+KKKME
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619
Query: 1624 GDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRAN 1683
GDLNEMEIQL+HANR AAEA + +++ Q +LKDTQ+ LDDA+R DDLKE +A+VERR N
Sbjct: 1620 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1679
Query: 1684 LMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
L+QAE+EELRA +E+TER RK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+Q
Sbjct: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQT 1739
Query: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1803
E+E+ VQE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RLDE
Sbjct: 1740 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1799
Query: 1804 AEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863
AEQ+ALKGGKKQ+QKLEARVRELE+E+E+EQK N E+VKG+RK ERR+KELTYQTEEDRK
Sbjct: 1800 AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRK 1859
Query: 1864 NILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNK 1923
N+LRLQDLVDKLQ KVKAYKRQAEEAEEQ+N NL+KFRK+QHEL+EA+ERADIAESQVNK
Sbjct: 1860 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919
Query: 1924 LRVKSREVHTKVISEE 1939
LR KSR++ TK ++EE
Sbjct: 1920 LRAKSRDIGTKGLNEE 1935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 3107 bits (8055), Expect = 0.0
Identities = 1555/1932 (80%), Positives = 1752/1932 (90%), Gaps = 1/1932 (0%)
Query: 3 SDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTA 62
+D++MA FG AA +LRKSEKER+EAQ +PFD +T FV D KE +VKA + SREGGKV A
Sbjct: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
Query: 63 KTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
+TE G TVTVKEDQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
Query: 123 CVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
CVTVNPYKWLPVYN EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
Query: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
AGKTVNTKRVIQYFA+IA G++ K++ A+ +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
Query: 243 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 302
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQLKAER+YHIFYQILSNKKPEL++
Sbjct: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
Query: 303 MLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHY 362
MLL+T NPYD+AFVSQGE++V SIDD EELMATDSA D+LGFT++EK +YKLTGA+MHY
Sbjct: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
Query: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQ 422
GNMKFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNE+VTKGQ+VQQ
Sbjct: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
Query: 423 VYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
VY ++GALAKA+YEKMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 542
FTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
Query: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKD 602
FPKATD +FK KLY+ HLGKSNNFQKP+ KGK EAHFSL+HYAGTVDYNI GWL+KNKD
Sbjct: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
Query: 603 PLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKL 662
PLNETVV LYQKS++K +A LFS TA+ G KGGKKKGSSFQTVSAL RENLNKL
Sbjct: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
Query: 663 MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 722
MTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
Query: 723 KQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRD 782
+QRY++LN AIPEGQFIDS+K +EKLL S++IDH QYKFGHTKVFFKAGLLG LEEMRD
Sbjct: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
Query: 783 EKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKP 842
E+L+++ITR QA RG LMR+EF+K++ERR+++ IQ+NIRAFM VK+WPWMKLYFKIKP
Sbjct: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
Query: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADAL 902
LLKSAETEKEMA MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D L
Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
Query: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLE
Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVN 1022
LTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ+EEDKVN
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNE 1082
+L+K+K KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKL QES MD ENDK QL E
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 1083 KLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
KLKKKEF+++ KIEDEQ LA+QLQKK+KE QARIEELEEE+EAER +RAK EK RSD
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
Query: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHAD 1202
LSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEE+TLQHEATAAALRKKHAD
Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
Query: 1203 SVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSE 1262
SVAELGEQID+LQRVKQKLEKEKSE K+E++D+ SNME + KAKAN EK+ RTLEDQ +E
Sbjct: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
Query: 1263 IKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQ 1322
+ K EE QR +N+ + Q+A+L TE+GE +RQL+EK+A++SQL+RGK ++TQQ+E+LKRQ
Sbjct: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
Query: 1323 LEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETD 1382
LEEE KAK+ LAHALQSARHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETD
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
Query: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAA 1442
AIQRTEELEEAKKKLAQRLQDAEE VEAVN+KC+SLEKTK RLQNE+EDLM+DVERSNAA
Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
Query: 1443 CIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETL 1502
ALDKKQRNFDK+LAEWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KNAYEESL+HLET
Sbjct: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
Query: 1503 KRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKI 1562
KRENKNLQ+EISDLTEQ+ EGGK++HELEKV+KQL+ EK ELQ++LEEAEASLEHEEGKI
Sbjct: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
Query: 1563 LRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKM 1622
LR QLE NQ+K+EI+RK+AEKDEE++Q KRNH RVV+S+Q++LDAE RSRN+ LR+KKKM
Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
Query: 1623 EGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRA 1682
EGDLNEMEIQL+HANR AAEA + +++ Q +LKDTQ+ LDDA+R DDLKE +A+VERR
Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 1683 NLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQ 1742
NL+QAE+EELRA +E+TER RK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q+Q
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Query: 1743 GEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1802
E+E+ VQE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RLD
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 1803 EAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDR 1862
EAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQK N E+VKG+RK ERR+KELTYQTEED+
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 1863 KNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVN 1922
KN+LRLQDLVDKLQ KVKAYKRQAEEAEEQ+N NL+KFRK+QHEL+EA+ERADIAESQVN
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 1923 KLRVKSREVHTK 1934
KLR KSR++ K
Sbjct: 1921 KLRAKSRDIGAK 1932
Score = 209 bits (533), Expect = 2e-53
Identities = 208/938 (22%), Positives = 425/938 (45%), Gaps = 87/938 (9%)
Query: 834 MKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
+KL ++ L S E EK++ + + E+ K +L E K +E ++ L +K L+
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKV---RMDLERAKRKL---EGDLKLTQESIMDLENDKLQLEE 1080
Query: 894 QVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAED-EEEINAELTAKKRKLEDECS 952
+++ + + + + +QL+ K+KE R E+ EEE+ AE TA+ K+E S
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARA-KVEKLRS 1139
Query: 953 ELKKDIDDLELTLAK----------VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002
+L ++++++ L + + K++ A K++ EE E A ++K A
Sbjct: 1140 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1199
Query: 1003 LQEAHQ-QTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEG 1061
A + +D+LQ + K L K K++ + ++DD+ ++EQ K +LE+ R LE
Sbjct: 1200 DSVAELGEQIDNLQRVKQK---LEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLED 1256
Query: 1062 DLKLAQESTMDTENDKQQLNE---KLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQAR 1118
A E + E ++ LN+ + K + E L ++E+++AL QL + +
Sbjct: 1257 Q---ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313
Query: 1119 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1178
+E+L+ ++E E ++ + + + E+ EE A + + K +E +
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
Query: 1179 RRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASN 1238
R E +Q +KK A + + E ++++ LEK K L+ EI DL +
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 1239 METVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEK 1298
+E + A A +K R + L+E K K EE Q + + L TE + +E
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
Query: 1299 DAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYE---EEQ 1355
+ R + ++I +L QL E K H L+ R ++ + + + EE
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKN----VHELEKVRKQLEVEKLELQSALEEA 1549
Query: 1356 EAKAELQRG-MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSK 1414
EA E + G + +A E Q + + E ++ EE+E+AK+ + + + ++A
Sbjct: 1550 EASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS 1609
Query: 1415 CASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEAS 1474
+ + K++++ ++ ++ I + +N K+ ++ +L ++TQ +L+ +
Sbjct: 1610 RNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL-------KDTQIQLDDA 1662
Query: 1475 QKESRSLSTELFKVK---NAYEESLDHL----ETLKRENKNLQQEISDLTEQIAEGGKHI 1527
+ + L + V+ N + L+ L E +R K +QE+ + +E++
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1722
Query: 1528 HELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEL 1587
L KK+++ + ++LQ+ +EEA + E K + + + E+ +K + L
Sbjct: 1723 TSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEEL-KKEQDTSAHL 1781
Query: 1588 DQLKRNHLRVVESMQSTLD-AEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
+++K+N + ++ +Q LD AE + + +K+E + E+E +L ++ AE+++
Sbjct: 1782 ERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG 1841
Query: 1647 LRNTQGILKDTQ----------LHLDDAI-----------RGQDDLKEQ----------- 1674
+R ++ +K+ L L D + R ++ +EQ
Sbjct: 1842 MRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKV 1901
Query: 1675 ---LAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709
L E RA++ +++V +LRA +KM ++E
Sbjct: 1902 QHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
Score = 191 bits (484), Expect = 8e-48
Identities = 193/870 (22%), Positives = 390/870 (44%), Gaps = 125/870 (14%)
Query: 1086 KKEFEMSNLQGKIEDEQALAIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
K F++ L E E+ +A ++ +IKE + E +E+E + S + +++DL
Sbjct: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889
Query: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADS 1203
+++ + L +A I+ + EA+ ++M LE+ + A A ++K D
Sbjct: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE-EMNAELTAKKRKLEDE 948
Query: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
+EL + ID L+ K+EKEK + ++ +L M + + A K E
Sbjct: 949 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK----------EK 998
Query: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
K +E Q+ +++L ++ + V+ LS+ K QQ+++L+ L
Sbjct: 999 KALQEAHQQALDDLQVEEDK------------------VNSLSKSKVKLEQQVDDLEGSL 1040
Query: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
E+E K + L A + D L +E + + K +L+ + K ++ Q +K E +
Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
Query: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAAC 1443
+ + L++ K+ R+++ EE +EA + A +EK + L E+E++ +E + A
Sbjct: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
Query: 1444 ---IALDKKQR-NFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHL 1499
I ++KK+ F K+ + ++ + +A A +K+ EL E +D+L
Sbjct: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212
Query: 1500 ETLK----RENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
+ +K +E + E+ D+T + + K LEKV + L+ + +E + LEEA+ SL
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
Query: 1556 EHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDA 1615
+ ++Q E E+ R++ EK+ + QL R L + M+
Sbjct: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316
Query: 1616 LRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQL 1675
+K+++E + A A AL++ R+ +L++ + + K +L
Sbjct: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359
Query: 1676 AMVERRANLMQAEVEELRA-----SLERTER---GRKMAEQELLDASERVQLLHTQNTSL 1727
V +AN +EV + R +++RTE +K Q L DA E V+ ++ + +SL
Sbjct: 1360 QRVLSKAN---SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
Query: 1728 INTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787
TK +L Q E+ED++ + + A A L++ +
Sbjct: 1417 EKTKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQ 1448
Query: 1788 KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKH 1847
+N ++ + + + + +E+ Q L+ +K+ + L + +L++ E +H +E K K+
Sbjct: 1449 RNFDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKN 1506
Query: 1848 -ERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE 1906
+ + +LT Q E KN+ L+ + +L+ + + EEAE K + Q E
Sbjct: 1507 LQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLE 1566
Query: 1907 LEEAKERADIAESQVNKLRVKSREVHTKVI 1936
+ K + ++ ++ +++ H +V+
Sbjct: 1567 FNQIKAEIERKLAEKDEEMEQAKRNHQRVV 1596
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 2576 bits (6677), Expect = 0.0
Identities = 1294/1932 (66%), Positives = 1613/1932 (83%), Gaps = 8/1932 (0%)
Query: 6 EMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSRE-GGKVTAKT 64
+++ GE+A +LR+ +E + P+D K V+V D +++YV+A V+S GG+VT +T
Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104
Query: 65 EAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
+ + V+E ++ MNPP++D +EDMAMMTHL+E +VL+NL++RYA WMIYTYSGLFCV
Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164
Query: 125 TVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY VV AY+GK+R ++PPHI++++DNAY ML +R+NQS+LITGESGAG
Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224
Query: 185 KTVNTKRVIQYFATIAVTGEK--KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
KTVNTKRVIQYFA +A G+ KK + + K GTLEDQII ANP +EAFGNAKT+RND
Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284
Query: 243 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 302
NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV FQL ERSYH++YQILS +KPEL +
Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344
Query: 303 MLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHY 362
MLL++ NPYD+ F SQG ITV +++D EEL+ATD A+DILGF+ DEK A YK+ GA++H+
Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404
Query: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQ 422
GNMKFKQKQREEQAE DGTE ADKAAYL ++S DLLK L +PRV+VGNE+VTKGQ+V+Q
Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464
Query: 423 VYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
V AVGALAKA Y+++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS EQLCIN
Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524
Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 542
FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL CI+LIEKP+GI SILEEECM
Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584
Query: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKP-AKGKPEAHFSLVHYAGTVDYNIAGWLDKNK 601
FPKA+D SF+ KLY+ H GKS NFQ+P+P K K +AHF +VHYAG V Y+I GWL+KNK
Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644
Query: 602 DPLNETVVGLYQKSAMKTLAFLF---SGAQTAEAEGGGGKKGGKKKGSSFQTVSALFREN 658
DPLNETVV ++QKS + LA L+ +G+ + E G K+ +KK +SFQTVS L +EN
Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEK-RKKAASFQTVSQLHKEN 703
Query: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718
LNKLMTNLR+T PHFVRCI+PNE KTPG M+ LVLHQLRCNGVLEGIRICR+GFP+R+L
Sbjct: 704 LNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLL 763
Query: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLE 778
Y DF+QRY++LN SAIP+ F+DS+KA+EKLLGS+++DHTQY+FGHTKVFFKAGLLG LE
Sbjct: 764 YTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLE 823
Query: 779 EMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYF 838
E+RD++LA+++T QA RG LMR+E+++++ R+++F IQ+NIRAF VK+W WMKL+F
Sbjct: 824 ELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFF 883
Query: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
K+KPLL+SA+ E+E+A ++ E + LA EAKR+ELEE V++ QEKNDL LQ+QAE
Sbjct: 884 KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943
Query: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
D LADAEERC LIK+K+QLE K+KE++ER EDEEE+NA+L A++RKLEDEC+ELKKDI
Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
DDL+LTLAK EKEK ATENKVKNLTEEMA LDE++A+LTKEKKALQEAHQQ L DLQ EE
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEE 1063
Query: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078
D+V+ LTKAK +LEQQV+DLE SLEQEKKL MD ERAKRKLEGDLKL QES D DKQ
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123
Query: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
QL EKLKKK+ E+S L ++EDEQ L Q+QKKIKELQAR EELEEE+EAERA+RA+ EK
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183
Query: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198
QR++ +RELEE+SERLEEAGGA++ Q E +KREAE ++RR+LEE+ L+HEAT AALR+
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243
Query: 1199 KHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLED 1258
K A+ AELGEQ+DSLQRV+QKLEKEKSEL+ME++DLA+N+ET+++AKA+ EK+CRT ED
Sbjct: 1244 KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303
Query: 1259 QLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318
QLSE K K EE QR + + S Q+ RL TESGE SR L+EK+ ++SQLSRGK Q +EE
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363
Query: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
L+RQLEEE+KAKS LAHA+Q+ RHDCDLLREQ+EEE EA+AELQR +SKAN+EVAQWR+K
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423
Query: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
YE DAIQRTEELEEAKKKLA RLQ+AEE VEA N+KC+SLEK K RLQ E ED+ +++ER
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483
Query: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498
+ +A ALDKKQR+ ++ L E +++ EE Q ELEA+Q+ESR L TELF++++ +EE+L+
Sbjct: 1484 ATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEA 1543
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE 1558
LETLKRENKNLQ+EISDLT+Q++ GK I ELEK KK L+ EKSE+Q +LEEAE +LE E
Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELE 1603
Query: 1559 EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618
E K LRIQLEL+QVK+E+DRK+AEKDEE L+RNH R VES+Q++LDAE R+RN+ALR+
Sbjct: 1604 ETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRL 1663
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678
KKKMEGDLN++E+QL HA RQA EA R Q LK+ Q D+ R +L EQ +
Sbjct: 1664 KKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQAL 1723
Query: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
ERRA+L+ AE+EELRA+LE+ ER R++AEQELL+A+ER+ LLH+QNT L+N KKKLE D+
Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783
Query: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798
+Q+ GE+E+ QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK +EQTV++LQ
Sbjct: 1784 AQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQ 1843
Query: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT 1858
RL+EAEQ AL+GGKKQ+QKLEA+VRELE+E+++EQK + EA+KG+RKHERRVKEL YQ
Sbjct: 1844 ARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQA 1903
Query: 1859 EEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918
EEDRKN+ R+QDLVDKLQ+KVK+YKRQ EEAE+Q+N NLAK+RK QHEL++A+ERAD+AE
Sbjct: 1904 EEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963
Query: 1919 SQVNKLRVKSRE 1930
+Q NKLR ++R+
Sbjct: 1964 TQANKLRARTRD 1975
Score = 224 bits (571), Expect = 6e-58
Identities = 209/928 (22%), Positives = 424/928 (45%), Gaps = 62/928 (6%)
Query: 1030 KLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDK----QQLNEKLK 1085
KL ++ L S + E++L L R L G L A+ + E Q+ N+
Sbjct: 880 KLFFKMKPLLRSAQAEEELAA-LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLAL 938
Query: 1086 KKEFEMSNLQGKIEDEQALA---IQLQKKIKELQARIEELEEEIEAERASRA-KAEKQRS 1141
+ + E NL E L +QL+ K+KEL R+E+ EEE+ A+ A+R K E + +
Sbjct: 939 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLED-EEEVNADLAARRRKLEDECT 997
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAA------A 1195
+L ++++++ L +A K+++A K++ EE E+ A A
Sbjct: 998 ELKKDIDDLKLTLAKA----------EKEKQATENKVKNLTEEMAALDESVARLTKEKKA 1047
Query: 1196 LRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRT 1255
L++ H ++ +L + D + L K K L+ ++ DL ++E K + + E+ R
Sbjct: 1048 LQEAHQQALGDLQAEEDRVSA----LTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRK 1103
Query: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
LE L + + + +L + + +E + S +++++ + +Q+ + + +
Sbjct: 1104 LEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQAR 1163
Query: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
EEL+ +LE E A++ + A + + L E+ EE A A + G K +E+ +
Sbjct: 1164 AEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRL 1223
Query: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMID 1435
R + E A++ + ++K A+ + E V+++ LEK K L+ EV+DL +
Sbjct: 1224 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 1283
Query: 1436 VERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEES 1495
VE A + +K R ++ L+E K K EE Q +L + + L TE ++ EE
Sbjct: 1284 VETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEK 1343
Query: 1496 LDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
+ L R Q + +L Q+ E K L + L H+ L+ EE EA
Sbjct: 1344 ECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE-EAEA 1402
Query: 1556 EHEEGKIL-RIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRND 1614
+ E ++L + E+ Q +S+ + ++ EEL++ K+ ++ + ++A +
Sbjct: 1403 QAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSS 1462
Query: 1615 ALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQ 1674
+ K +++ + ++ ++L A AA + R+ + L++ + R +++++ +
Sbjct: 1463 LEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR-------RQEEEMQRE 1515
Query: 1675 LAMVERRANLMQAEV-------EELRASLERTERGRKMAEQELLDASERVQLLHTQNTSL 1727
L +R + + E+ EE +LE +R K ++E+ D +++V L L
Sbjct: 1516 LEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL 1575
Query: 1728 INTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERM 1786
TKK LE + S+IQ +E+ E K + + + + E+ +K + +
Sbjct: 1576 EKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANL 1635
Query: 1787 KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRK 1846
++N ++ V+ LQ LD AE A + +K+E + +LE ++ + EA R
Sbjct: 1636 RRNHQRAVESLQASLD-AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRL 1694
Query: 1847 HERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE 1906
+ ++KE +E+++ L + QA+ E ++++ A+ +L+
Sbjct: 1695 MQAQLKEEQAGRDEEQRLAAELHE--------------QAQALERRASLLAAELEELRAA 1740
Query: 1907 LEEAKERADIAESQVNKLRVKSREVHTK 1934
LE+ + +AE ++ + + +H++
Sbjct: 1741 LEQGERSRRLAEQELLEATERLNLLHSQ 1768
Score = 161 bits (408), Expect = 5e-39
Identities = 192/870 (22%), Positives = 362/870 (41%), Gaps = 131/870 (15%)
Query: 1089 FEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
F+M L + E+ LA L+ +++ L+ + E + + + ++++DL+ +L+
Sbjct: 883 FKMKPLLRSAQAEEELAA-LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQ 941
Query: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELG 1208
+ L +A I+ + E + +++ LE+ + A AA R+K D EL
Sbjct: 942 AEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEE-EVNADLAARRRKLEDECTELK 1000
Query: 1209 EQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEE 1268
+ ID L+ K EKEK + ++ +L M + ++ A K E K +E
Sbjct: 1001 KDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTK----------EKKALQE 1050
Query: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328
Q+ + +L A++ R VS L++ K QQ+E+L+ LE+E K
Sbjct: 1051 AHQQALGDLQAEEDR------------------VSALTKAKLRLEQQVEDLECSLEQEKK 1092
Query: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE 1388
+ + + AK +L+ + VA DA Q +
Sbjct: 1093 LRM---------------------DTERAKRKLEGDLKLTQESVA--------DAAQDKQ 1123
Query: 1389 ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDK 1448
+LEE KK L VE A ++K + LQ E+L ++E AA ++K
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183
Query: 1449 KQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKN 1508
++ + L E ++ EE ++ R EL +++ EE+ E +
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243
Query: 1509 LQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLE 1568
Q E AE G+ + L++V+++L+ EKSEL+ +++ A++E
Sbjct: 1244 KQ------AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE-----------T 1286
Query: 1569 LNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEI---RSRNDALRIKKKMEGD 1625
L + K+ ++ +++L + K ++V E + DA R + ++ + + +E +
Sbjct: 1287 LTRAKASAEKLCRTYEDQLSEAK---IKVEELQRQLADASTQRGRLQTESGELSRLLE-E 1342
Query: 1626 LNEMEIQLNHANRQAAEALRNLRNT---QGILKDTQLHLDDAIRGQDDL--------KEQ 1674
+ QL+ AA++L LR + K H A+R DL E
Sbjct: 1343 KECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEA 1402
Query: 1675 LAMVERRANLMQAEVEELRA-----SLERTER---GRKMAEQELLDASERVQLLHTQNTS 1726
A ++R + AEV + R+ +++RTE +K L +A E V+ + + +S
Sbjct: 1403 QAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSS 1462
Query: 1727 LINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786
L K +L+T E ED+ E A T AA ++ ++ HLER
Sbjct: 1463 LEKAKLRLQT-------ESEDVTLELERA--------TSAAAALDKKQR------HLERA 1501
Query: 1787 KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRK 1846
+ + +++Q L EA Q +G ++ +L E +E+ ++ N +
Sbjct: 1502 LEERRRQEEEMQREL-EAAQRESRGLGTELFRLRHGHEEALEALETLKREN-------KN 1553
Query: 1847 HERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE 1906
+ + +LT Q K+I L+ L+ + + EEAE + K ++Q E
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 1907 LEEAKERADIAESQVNKLRVKSREVHTKVI 1936
L + K D ++ ++ R H + +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAV 1643
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 2315 bits (5998), Expect = 0.0
Identities = 1156/1934 (59%), Positives = 1539/1934 (79%), Gaps = 10/1934 (0%)
Query: 6 EMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQ-SREGGKVTAKT 64
+++ GEAA FLR+SE E + Q D K ++ D + +Y++A V+ S + G V +T
Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
Query: 65 EAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
G ++++KED++ MNPP+++ IEDMAM+THL+E +VL+ LK RY WMIYTYSGLFCV
Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
Query: 125 TVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
Query: 185 KTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNS 244
KTVN+K +IQYFATIA E +K+ QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
Query: 245 SRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEML 304
SRFGKFIR+HFGA G L+S DI+ YLLEKSRV FQ ER+YHIFYQILS +K EL ++L
Sbjct: 255 SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
Query: 305 LITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGN 364
L++ NP DF F S G +TV S+DD EEL+AT+ A+DILGF DEK YKLTGA+MH+GN
Sbjct: 314 LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
Query: 365 MKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVY 424
MKFKQK REEQ E DGTE ADKAA+L +NS++L+K L +PR+KVGNE+VT+GQT++QV
Sbjct: 374 MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
Query: 425 NAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
AVGAL+K++YE+MF W+V RIN+ LD K RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 434 CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
NEKLQQFFN HMFVLEQEEYKKE IEW I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 494 NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
Query: 545 KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPL 604
KATD +FK KL++ H GKS + QKPKP K K EAHF LVHYAG V YNI+GWL+KNKD L
Sbjct: 554 KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
Query: 605 NETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664
NETVV ++QKS+ + LA LF + ++ G+K +KKG+SFQTV++L +ENLNKLMT
Sbjct: 614 NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK-RKKGASFQTVASLHKENLNKLMT 672
Query: 665 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724
NL+ST PHFVRCI PN K PG ++ LVL QLRCNGVLEG RICR+GFP+R+ YADFKQ
Sbjct: 673 NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732
Query: 725 RYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEK 784
RY +LN P+ +F+ S+KA+E+LLGS+EIDHTQY+FG TKVFFKAG LG LE +RDE+
Sbjct: 733 RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792
Query: 785 LAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLL 844
L+++ T QA +G LMR++F+K++E R+++ IQ+NIRAFM VK+WPWM+L+FKIKPL+
Sbjct: 793 LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
KS+E +E+A +KEE + ++ L K+E +R+EL+ K V+L QEKNDL LQ+QAE + LA+
Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE
Sbjct: 913 VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
L K EKEK TE+KVKNLTEE+ L+E I+KL + K +QEAHQQTLDDL MEE+K+++L
Sbjct: 973 LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
Query: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL 1084
+KA KLEQQVD+LEG+LEQE+K M+ ER KLEG+LKL +ES + E+ ++ L E+L
Sbjct: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
Query: 1085 KKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
+KKE E+S + K+E+E+ L QLQK +KELQ +I++L+E++EAER +RAK E++R+DL+
Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
Query: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSV 1204
++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EE+TL E T+A+L+K+HADS+
Sbjct: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212
Query: 1205 AELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264
AEL Q+++LQ+VKQKLEK+KS+L++E++DL + +E +++AKAN EK+C E++L E
Sbjct: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272
Query: 1265 TKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLE 1324
K ++ +L N+L+AQK +L +ESGEF R+L+EK+A+++QLSR K FT+QIE+L+ QLE
Sbjct: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332
Query: 1325 EETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAI 1384
+ETK++S LAHALQ A+ DCDLLREQYEEEQE KAEL R +SK N+E+ QWR KYE + I
Sbjct: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392
Query: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACI 1444
QRTE+LE+AKK+LA RLQ+A E + N++ ASLE+ + +LQ E+ D + D+ + +A
Sbjct: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452
Query: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKR 1504
LD+KQ K LA+WKQK+EE+QA L+ASQKE ++LSTEL K+KN YEES+ ETL+R
Sbjct: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512
Query: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564
ENKNLQ+EIS+LT Q+ EG K++ E+EKVKK ++ EK+E+Q +LEE E +LE E KIL
Sbjct: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572
Query: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEG 1624
QLEL + K+E++RK++EKDEE++ +R ++S+QS+LD+E +SR + R+KKKME
Sbjct: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632
Query: 1625 DLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANL 1684
DLNEME+QL+ ANRQ +EA ++L Q +KD Q+ LDD+ + DLKEQ+A+ ERR +L
Sbjct: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692
Query: 1685 MQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744
+Q+E+E+LR+ E+TERGR+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D++++Q E
Sbjct: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
Query: 1745 MEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1804
E++VQE +NAEEKAKKA +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL EA
Sbjct: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812
Query: 1805 EQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKN 1864
EQ+AL G +KQIQKLE+RVRELE E+E E + + EA +G R+ ER +KELTYQ EED+KN
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872
Query: 1865 ILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKL 1924
+ R+Q +DKLQ KV+ YK+Q E AE Q+N L+K++K QHEL E KERA++AESQVNKL
Sbjct: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932
Query: 1925 RVKSREVHTKVISE 1938
++K+RE KV E
Sbjct: 1933 KIKAREFGKKVQEE 1946
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 1424 bits (3687), Expect = 0.0
Identities = 781/1913 (40%), Positives = 1186/1913 (61%), Gaps = 32/1913 (1%)
Query: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
AK V+V K+ + A ++ +G +V + E G VTV +D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 273 KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEEL 332
KSR Q + ER++HIFY +++ K ++ LL+ ++ F+S G + +P+ D E
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
Query: 333 MATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTS 392
T A+ I+GF+ +E+++I K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
Query: 393 LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD- 451
+N D +S+ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+ LD
Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 512 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 569 PKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA- 627
PK K K E FS++HYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 628 ------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
Q A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 742 SKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLM 801
K+A ++ ++E+D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG+L
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 802 RVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
R F K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 921
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGS 1041
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1042 LEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDE 1101
L++E+K +LE+ KRKLEGD E D + +L +L KKE E+ +++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1102 QALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1162 SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL 1221
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
+K K L+ E DLA + + +AK E + LE Q+ E+++K + +R EL+ +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341
+L E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461
++ + E + LEKTK RLQ E++DL++D++ L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1462 ---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL 1516
KY E +AE EA +KE+++LS + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 1517 TEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
+ GK++HELEK K+ L+ + E++T LEE E L+ E LR+++ + +K +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
+R + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
+ EA++ LR Q +KD Q L+DA +D++ E++A ++A++ +L+ L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAE 1756
ER RK A+ E + +E + + +L + K++LE I+Q++ E+E+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1816
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
Query: 1817 QKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1876
LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 1877 TKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
+VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 215 bits (548), Expect = 3e-55
Identities = 189/901 (20%), Positives = 428/901 (47%), Gaps = 53/901 (5%)
Query: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEESTLQHEATAAALRK 1198
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971
Query: 1199 KHADSVAE---LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRT 1255
+ + A+ L ++I + KL KE+ L+ I+DL +N+ + N K+
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNK 1031
Query: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
E +SE++ + +++++ EL K +L ++ +F Q+ + A +++L ++
Sbjct: 1032 HESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1091
Query: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
++ +L++E K+ ++ L+E + E+ A+ + ++ E+
Sbjct: 1092 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
Query: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNSKCASLEKTKQRLQNEVEDLMI 1434
+T+ E D + T +E + K Q + ++ + E S A +++ +Q+ VE+L
Sbjct: 1152 KTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 1435 DVERSNAACIALDKKQRNFDK----------VLAEWKQKYEETQAELEASQKESRS---- 1480
+E+ A LDK ++ +K VL + KQ+ E + +LEA +E +S
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 1481 -------LSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
L+ ++ K++N E L + + L ++++ L+ Q+ + + + E +
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 1534 K-------KQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
K +QL+ E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1389
Query: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
L++ K+ + +E++ + + + + + K +++ +L+++ + L++ + + +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 1647 LRNTQGILKD----TQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERG 1702
R +L + + + D+ R + + +E+ E +A + +EE + E ER
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
Query: 1703 RKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEE-KAKK 1761
KM + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1623
Query: 1821 ARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + R + + + K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS--RDEIFATAKENEKK 1681
Query: 1881 AYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV--NKLRVKSREVHTKVISE 1938
A +A+ + Q ++ A+ + Q +LE+ + ++A S N L+ + R + ++
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 1939 E 1939
E
Sbjct: 1742 E 1742
Score = 97.8 bits (242), Expect = 9e-20
Identities = 85/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
K + ++++ + E E +++ A A +K+LE + DL+LQ + A+
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADS---AIKG 1639
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
EE QL K L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 1640 REEAIKQLRK----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLE--------------GDLKLAQEST 1070
+ K QQ + L L E+ E A+++LE G +K +ST
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
Query: 1071 MDTENDK-----QQLNEK----------LKKKEFEMSNLQGKIEDEQALAIQLQKKIKEL 1115
+ K +Q+ ++ LK+K+ ++ + ++EDE+ +A Q +++ ++
Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
Query: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
Query: 1175 FQKMRR 1180
F RR
Sbjct: 1936 FVPSRR 1941
Score = 74.7 bits (182), Expect = 8e-13
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677
+++ E E E+Q +Q AE L+ L L + + L + ++ + +L +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
+ R + E+EE+ +E ++ E+E +R Q L + + LE
Sbjct: 909 MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 958
Query: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
+ + + + + E AE K KK + +E+ D + L + +K +E+ + DL
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
L E E+ A K K K E+ + ELE ++ E+K E K RK E + Q
Sbjct: 1012 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917
+ + I L+ + K + +++A + ++ Q N L K R+L+ + + +E D
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 1918 ESQVNKLRVKSREV 1931
+ NK + R++
Sbjct: 1131 RAARNKAEKQKRDL 1144
Score = 72.4 bits (176), Expect = 4e-12
Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)
Query: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728
L V R+ MQA+ +EL+ + ER ++ K EQ+ +E LL Q T L
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782
+++ ++ + E+E+I+ E E++ ++ + MA+++ +EQ
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838
R K +E+ + +++ E E L + ++ K LE R+ +L + + E++
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
+ K + EL+ A R D +Q N K RE+
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1116
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 1424 bits (3687), Expect = 0.0
Identities = 781/1913 (40%), Positives = 1186/1913 (61%), Gaps = 32/1913 (1%)
Query: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
AK V+V K+ + A ++ +G +V + E G VTV +D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 273 KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEEL 332
KSR Q + ER++HIFY +++ K ++ LL+ ++ F+S G + +P+ D E
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
Query: 333 MATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTS 392
T A+ I+GF+ +E+++I K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
Query: 393 LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD- 451
+N D +S+ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+ LD
Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 512 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 569 PKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA- 627
PK K K E FS++HYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 628 ------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
Q A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 742 SKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLM 801
K+A ++ ++E+D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG+L
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 802 RVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
R F K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 921
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGS 1041
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1042 LEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDE 1101
L++E+K +LE+ KRKLEGD E D + +L +L KKE E+ +++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1102 QALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1162 SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL 1221
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
+K K L+ E DLA + + +AK E + LE Q+ E+++K + +R EL+ +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341
+L E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461
++ + E + LEKTK RLQ E++DL++D++ L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1462 ---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL 1516
KY E +AE EA +KE+++LS + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 1517 TEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
+ GK++HELEK K+ L+ + E++T LEE E L+ E LR+++ + +K +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
+R + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
+ EA++ LR Q +KD Q L+DA +D++ E++A ++A++ +L+ L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAE 1756
ER RK A+ E + +E + + +L + K++LE I+Q++ E+E+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1816
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
Query: 1817 QKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1876
LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 1877 TKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
+VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 215 bits (548), Expect = 3e-55
Identities = 189/901 (20%), Positives = 428/901 (47%), Gaps = 53/901 (5%)
Query: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEESTLQHEATAAALRK 1198
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971
Query: 1199 KHADSVAE---LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRT 1255
+ + A+ L ++I + KL KE+ L+ I+DL +N+ + N K+
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNK 1031
Query: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
E +SE++ + +++++ EL K +L ++ +F Q+ + A +++L ++
Sbjct: 1032 HESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1091
Query: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
++ +L++E K+ ++ L+E + E+ A+ + ++ E+
Sbjct: 1092 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
Query: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNSKCASLEKTKQRLQNEVEDLMI 1434
+T+ E D + T +E + K Q + ++ + E S A +++ +Q+ VE+L
Sbjct: 1152 KTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 1435 DVERSNAACIALDKKQRNFDK----------VLAEWKQKYEETQAELEASQKESRS---- 1480
+E+ A LDK ++ +K VL + KQ+ E + +LEA +E +S
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 1481 -------LSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
L+ ++ K++N E L + + L ++++ L+ Q+ + + + E +
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
Query: 1534 K-------KQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
K +QL+ E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1389
Query: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
L++ K+ + +E++ + + + + + K +++ +L+++ + L++ + + +
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 1647 LRNTQGILKD----TQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERG 1702
R +L + + + D+ R + + +E+ E +A + +EE + E ER
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
Query: 1703 RKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEE-KAKK 1761
KM + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1623
Query: 1821 ARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + R + + + K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS--RDEIFATAKENEKK 1681
Query: 1881 AYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV--NKLRVKSREVHTKVISE 1938
A +A+ + Q ++ A+ + Q +LE+ + ++A S N L+ + R + ++
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 1939 E 1939
E
Sbjct: 1742 E 1742
Score = 74.7 bits (182), Expect = 8e-13
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677
+++ E E E+Q +Q AE L+ L L + + L + ++ + +L +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
+ R + E+EE+ +E ++ E+E +R Q L + + LE
Sbjct: 909 MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 958
Query: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
+ + + + + E AE K KK + +E+ D + L + +K +E+ + DL
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
L E E+ A K K K E+ + ELE ++ E+K E K RK E + Q
Sbjct: 1012 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917
+ + I L+ + K + +++A + ++ Q N L K R+L+ + + +E D
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 1918 ESQVNKLRVKSREV 1931
+ NK + R++
Sbjct: 1131 RAARNKAEKQKRDL 1144
Score = 72.4 bits (176), Expect = 4e-12
Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)
Query: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728
L V R+ MQA+ +EL+ + ER ++ K EQ+ +E LL Q T L
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782
+++ ++ + E+E+I+ E E++ ++ + MA+++ +EQ
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838
R K +E+ + +++ E E L + ++ K LE R+ +L + + E++
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
+ K + EL+ A R D +Q N K RE+
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1116
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 1422 bits (3681), Expect = 0.0
Identities = 781/1916 (40%), Positives = 1185/1916 (61%), Gaps = 31/1916 (1%)
Query: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
AK V+V K+ + A ++ +G +V + E G VTV +D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 ---GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 269
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 270 LLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQ 329
LLEKSR Q + ER++HIFY +++ K ++ LL+ ++ F+S G + +P+ D
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330
Query: 330 EELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
E T A+ I+GF+ +E+++I K+ +V+ GN+ FK+++ +QA A K +
Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390
Query: 390 LTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQ 449
L +N D +S+ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+
Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450
Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510
Query: 509 IEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569
Query: 566 FQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFS 625
FQKPK K K E FS++HYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627
Query: 626 GA-------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 678
Q A+ K K F+TV L++E L KLMT LR+T P+FVRCII
Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687
Query: 679 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 738
PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G
Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746
Query: 739 FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRG 798
F+D K+A ++ ++E+D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG
Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806
Query: 799 FLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+L R F K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++
Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQ 918
E +KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +
Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 919 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 978
LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986
Query: 979 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDL 1038
+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Query: 1039 EGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKI 1098
E L++E+K +LE+ KRKLEGD E D + +L +L KKE E+ ++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106
Query: 1099 EDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
+DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVK 1218
+T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 1219 QKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELS 1278
L+K K L+ E DLA + + +AK E + LE Q+ E+++K + +R EL+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1279 AQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQ 1338
+ +L E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1339 SARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405
Query: 1399 QRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLA 1458
+ +++ + E + LEKTK RLQ E++DL++D++ L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1459 EWK---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEI 1513
E K KY E +AE EA +KE+++LS + A EE+L+ E L+R NK L+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEM 1520
Query: 1514 SDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK 1573
DL + GK++HELEK K+ L+ + E++T LEE E L+ E LR+++ + +K
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580
Query: 1574 SEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQL 1633
+ +R + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640
Query: 1634 NHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELR 1693
+ A + EA++ LR Q +KD Q L+DA +D++ E++A ++A++ +L+
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700
Query: 1694 ASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEAR 1753
L ER RK A+ E + +E + + +L + K++LE I+Q++ E+E+
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGK 1813
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 1814 KQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVD 1873
I LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880
Query: 1874 KLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
K +VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 215 bits (548), Expect = 3e-55
Identities = 189/901 (20%), Positives = 428/901 (47%), Gaps = 53/901 (5%)
Query: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEESTLQHEATAAALRK 1198
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978
Query: 1199 KHADSVAE---LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRT 1255
+ + A+ L ++I + KL KE+ L+ I+DL +N+ + N K+
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNK 1038
Query: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
E +SE++ + +++++ EL K +L ++ +F Q+ + A +++L ++
Sbjct: 1039 HESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1098
Query: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
++ +L++E K+ ++ L+E + E+ A+ + ++ E+
Sbjct: 1099 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158
Query: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNSKCASLEKTKQRLQNEVEDLMI 1434
+T+ E D + T +E + K Q + ++ + E S A +++ +Q+ VE+L
Sbjct: 1159 KTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 1435 DVERSNAACIALDKKQRNFDK----------VLAEWKQKYEETQAELEASQKESRS---- 1480
+E+ A LDK ++ +K VL + KQ+ E + +LEA +E +S
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 1481 -------LSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
L+ ++ K++N E L + + L ++++ L+ Q+ + + + E +
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 1534 K-------KQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
K +QL+ E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1338 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1396
Query: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
L++ K+ + +E++ + + + + + K +++ +L+++ + L++ + + +
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 1647 LRNTQGILKD----TQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERG 1702
R +L + + + D+ R + + +E+ E +A + +EE + E ER
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1512
Query: 1703 RKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEE-KAKK 1761
KM + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1630
Query: 1821 ARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + R + + + K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS--RDEIFATAKENEKK 1688
Query: 1881 AYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV--NKLRVKSREVHTKVISE 1938
A +A+ + Q ++ A+ + Q +LE+ + ++A S N L+ + R + ++
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 1939 E 1939
E
Sbjct: 1749 E 1749
Score = 97.8 bits (242), Expect = 9e-20
Identities = 85/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
K + ++++ + E E +++ A A +K+LE + DL+LQ + A+
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADS---AIKG 1646
Query: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
EE QL K L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 1647 REEAIKQLRK----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLE--------------GDLKLAQEST 1070
+ K QQ + L L E+ E A+++LE G +K +ST
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 1071 MDTENDK-----QQLNEK----------LKKKEFEMSNLQGKIEDEQALAIQLQKKIKEL 1115
+ K +Q+ ++ LK+K+ ++ + ++EDE+ +A Q +++ ++
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942
Query: 1175 FQKMRR 1180
F RR
Sbjct: 1943 FVPSRR 1948
Score = 74.7 bits (182), Expect = 8e-13
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677
+++ E E E+Q +Q AE L+ L L + + L + ++ + +L +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
+ R + E+EE+ +E ++ E+E +R Q L + + LE
Sbjct: 916 MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 965
Query: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
+ + + + + E AE K KK + +E+ D + L + +K +E+ + DL
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
L E E+ A K K K E+ + ELE ++ E+K E K RK E + Q
Sbjct: 1019 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917
+ + I L+ + K + +++A + ++ Q N L K R+L+ + + +E D
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1918 ESQVNKLRVKSREV 1931
+ NK + R++
Sbjct: 1138 RAARNKAEKQKRDL 1151
Score = 72.4 bits (176), Expect = 4e-12
Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)
Query: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728
L V R+ MQA+ +EL+ + ER ++ K EQ+ +E LL Q T L
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782
+++ ++ + E+E+I+ E E++ ++ + MA+++ +EQ
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838
R K +E+ + +++ E E L + ++ K LE R+ +L + + E++
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
+ K + EL+ A R D +Q N K RE+
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1123
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 1422 bits (3681), Expect = 0.0
Identities = 781/1916 (40%), Positives = 1185/1916 (61%), Gaps = 31/1916 (1%)
Query: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
AK V+V K+ + A ++ +G +V + E G VTV +D + MNPPK+ K+EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
Query: 213 ---GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETY 269
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY
Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271
Query: 270 LLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQ 329
LLEKSR Q + ER++HIFY +++ K ++ LL+ ++ F+S G + +P+ D
Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330
Query: 330 EELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
E T A+ I+GF+ +E+++I K+ +V+ GN+ FK+++ +QA A K +
Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390
Query: 390 LTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQ 449
L +N D +S+ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+
Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450
Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510
Query: 509 IEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565
IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569
Query: 566 FQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFS 625
FQKPK K K E FS++HYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627
Query: 626 GA-------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 678
Q A+ K K F+TV L++E L KLMT LR+T P+FVRCII
Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687
Query: 679 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 738
PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G
Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746
Query: 739 FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRG 798
F+D K+A ++ ++E+D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG
Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806
Query: 799 FLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
+L R F K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++
Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866
Query: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQ 918
E +KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +
Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 919 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 978
LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986
Query: 979 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDL 1038
+K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Query: 1039 EGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKI 1098
E L++E+K +LE+ KRKLEGD E D + +L +L KKE E+ ++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106
Query: 1099 EDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
+DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 1159 GATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVK 1218
+T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 1219 QKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELS 1278
L+K K L+ E DLA + + +AK E + LE Q+ E+++K + +R EL+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1279 AQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQ 1338
+ +L E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1339 SARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405
Query: 1399 QRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLA 1458
+ +++ + E + LEKTK RLQ E++DL++D++ L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1459 EWK---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEI 1513
E K KY E +AE EA +KE+++LS + A EE+L+ E L+R NK L+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEM 1520
Query: 1514 SDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK 1573
DL + GK++HELEK K+ L+ + E++T LEE E L+ E LR+++ + +K
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580
Query: 1574 SEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQL 1633
+ +R + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640
Query: 1634 NHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELR 1693
+ A + EA++ LR Q +KD Q L+DA +D++ E++A ++A++ +L+
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700
Query: 1694 ASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEAR 1753
L ER RK A+ E + +E + + +L + K++LE I+Q++ E+E+
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGK 1813
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 1814 KQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVD 1873
I LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880
Query: 1874 KLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
K +VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 215 bits (548), Expect = 3e-55
Identities = 189/901 (20%), Positives = 428/901 (47%), Gaps = 53/901 (5%)
Query: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEESTLQHEATAAALRK 1198
L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978
Query: 1199 KHADSVAE---LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRT 1255
+ + A+ L ++I + KL KE+ L+ I+DL +N+ + N K+
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNK 1038
Query: 1256 LEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
E +SE++ + +++++ EL K +L ++ +F Q+ + A +++L ++
Sbjct: 1039 HESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE 1098
Query: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQW 1375
++ +L++E K+ ++ L+E + E+ A+ + ++ E+
Sbjct: 1099 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158
Query: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV-EAVNSKCASLEKTKQRLQNEVEDLMI 1434
+T+ E D + T +E + K Q + ++ + E S A +++ +Q+ VE+L
Sbjct: 1159 KTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 1435 DVERSNAACIALDKKQRNFDK----------VLAEWKQKYEETQAELEASQKESRS---- 1480
+E+ A LDK ++ +K VL + KQ+ E + +LEA +E +S
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 1481 -------LSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
L+ ++ K++N E L + + L ++++ L+ Q+ + + + E +
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1337
Query: 1534 K-------KQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
K +QL+ E++ LQ L+E + ++ E I + ++L+ K ++ + A E
Sbjct: 1338 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEA 1396
Query: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
L++ K+ + +E++ + + + + + K +++ +L+++ + L++ + + +
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 1647 LRNTQGILKD----TQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERG 1702
R +L + + + D+ R + + +E+ E +A + +EE + E ER
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1512
Query: 1703 RKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEE-KAKK 1761
KM + E+ D + L +K+ LET + +++ ++E++ E + E+ K +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKLE 1820
+ A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLE 1630
Query: 1821 ARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVK 1880
+++LE + +S K EA+K LRK + ++K+ + E+ R + R + + + K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS--RDEIFATAKENEKK 1688
Query: 1881 AYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV--NKLRVKSREVHTKVISE 1938
A +A+ + Q ++ A+ + Q +LE+ + ++A S N L+ + R + ++
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 1939 E 1939
E
Sbjct: 1749 E 1749
Score = 74.7 bits (182), Expect = 8e-13
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677
+++ E E E+Q +Q AE L+ L L + + L + ++ + +L +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
+ R + E+EE+ +E ++ E+E +R Q L + + LE
Sbjct: 916 MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 965
Query: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
+ + + + + E AE K KK + +E+ D + L + +K +E+ + DL
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
L E E+ A K K K E+ + ELE ++ E+K E K RK E + Q
Sbjct: 1019 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917
+ + I L+ + K + +++A + ++ Q N L K R+L+ + + +E D
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1918 ESQVNKLRVKSREV 1931
+ NK + R++
Sbjct: 1138 RAARNKAEKQKRDL 1151
Score = 72.4 bits (176), Expect = 4e-12
Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)
Query: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728
L V R+ MQA+ +EL+ + ER ++ K EQ+ +E LL Q T L
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782
+++ ++ + E+E+I+ E E++ ++ + MA+++ +EQ
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838
R K +E+ + +++ E E L + ++ K LE R+ +L + + E++
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
+ K + EL+ A R D +Q N K RE+
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1123
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 1402 bits (3630), Expect = 0.0
Identities = 773/1914 (40%), Positives = 1175/1914 (61%), Gaps = 37/1914 (1%)
Query: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
AK V+V K + A ++ G + + E G V V +D + MNPPK+ K+EDMA
Sbjct: 28 AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
+T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V Y+GKKR E P
Sbjct: 88 ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+
Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
Query: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272
QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE
Sbjct: 204 ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
Query: 273 KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYD-FAFVSQGEITVPSIDDQEE 331
KSR Q K ER++HIFY +LS L LL+ PY+ + F+S G +T+P D++
Sbjct: 261 KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
Query: 332 LMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLT 391
T A+ I+G +E++ + ++ V+ GN+ FK+++ +QA A K ++L
Sbjct: 319 FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
Query: 392 SLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD 451
+N D + + PR+KVG ++V K QT +Q A+ ALAKA YE+MF W+V RIN+ LD
Sbjct: 379 GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
Query: 452 -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
TK+ FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 439 KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
Query: 511 WEFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
W FIDFG+DL CI+LIEKP G I ++L+EEC FPKATD SF K+ ++ G FQ
Sbjct: 499 WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQ 557
Query: 568 KPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA 627
KPK K K A F ++HYAG VDY WL KN DPLN+ + L +S+ K ++ L+
Sbjct: 558 KPKQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
Query: 628 -------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680
Q A K + F+TV L++E L KLM LR+T+P+FVRCIIPN
Sbjct: 616 DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
Query: 681 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740
K G ++ LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L ++IP+G F+
Sbjct: 676 HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
Query: 741 DSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFL 800
D K+A ++ ++E+D Y+ G +KVFF+AG+L LEE RD K+ +I QA CRG+L
Sbjct: 735 DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
Query: 801 MRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860
R F K ++ ++ +Q N A++ +++W W +L+ K+KPLL+ + E+EM +EE
Sbjct: 795 ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
Query: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLE 920
K +E+ E + E+E LM EK LQ Q+QAE + A+AEE +L K +LE
Sbjct: 855 VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
Query: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980
++ R E+EEE L A+K+K++ EL++ +++ E K++ EK TE K+K
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEG 1040
L EE L++ KL KEKK L++ + +L EE+K +L K K K E + DLE
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 1041 SLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIED 1100
L +E+K +LE+ +RKLEGD + + + +L +L KKE E+ ++E+
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
Query: 1101 EQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
E A KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL ELE + LE+ +
Sbjct: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
Query: 1161 TSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQK 1220
T+AQ E+ KRE E +++ LEE HEA +R+KH+ +V EL EQ++ +RVK
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 1221 LEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ 1280
LEK K L+ E +LA+ ++ + + K + E + +E QL E++ K E +R+ EL+ +
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340
+L E + L + D+ S+L++ A Q+++ + L+EE + K +L+ L+
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ + REQ EEE+EAK L++ ++ +++VA + K E D++ E EE K+KL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
Query: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460
L+ + E + LEKTK RLQ E++DL++D++ + L+KKQ+ FD++LAE
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
Query: 1461 K---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISD 1515
K KY E +AE EA +KE+++LS + A EE+++ L+R NK + E+ D
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALS-----LARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 1516 LTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSE 1575
L + GK +HELEK K+ L+ + E++T LEE E L+ E LR+++ L +K++
Sbjct: 1509 LMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
Query: 1576 IDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNH 1635
+R + +DE+ ++ K+ +R V M++ L+ E + R+ A+ +KK+E DL ++E ++
Sbjct: 1569 FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
Query: 1636 ANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRAS 1695
AN+ EA++ LR Q +KD LDD ++++ Q E++ M+AE+ +L+
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
Query: 1696 LERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNA 1755
L ER ++ A+QE + ++ + + + K++LE I+Q++ E+E+
Sbjct: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748
Query: 1756 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1815
++ KKA + +L E+ + E ++ +E+ K+L+++L E E K
Sbjct: 1749 NDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKAS 1808
Query: 1816 IQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1875
I LEA++ +LE ++++E K A K +R+ E+++K++ Q +++R+N + +D DK
Sbjct: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868
Query: 1876 QTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
T++K KRQ EEAEE++ A RKLQ ELE+A E AD +V+ L+ K R
Sbjct: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 260 bits (665), Expect = 8e-69
Identities = 237/993 (23%), Positives = 464/993 (46%), Gaps = 103/993 (10%)
Query: 835 KLYFKIKPLLKSAETEKEMANMKEEFEK--TKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892
K+ I+ L + E E+E A K + EK T+ +L K E ++ LE++ L +EK L+
Sbjct: 940 KMQQNIQELEEQLE-EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 893 LQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE---- 948
++ L + EE+ L K K + EA I ++ ER EE+ EL +RKLE
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 949 ---DECSELKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDE 991
D+ +EL+ I +L++ LAK E+E K+ K++ L +++ L E
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 992 TIAK--------------LTKEKKALQEAHQQTLDDLQME-------EDKVNTLTK---- 1026
+ L +E +AL+ + TLD + E +VN L K
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 1027 -AKT----------KLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL-KLAQESTMDTE 1074
AKT K Q V++L LEQ K++ +LE+AK+ LE + +LA E + +
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 1075 NDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRA 1134
K K KK E ++ LQ K + + + +L K+ +LQ ++ + + + +
Sbjct: 1239 G-KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSS 1297
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGAT--------SAQIEMNKKREA--EFQKMRRDLEE 1184
K K S L +L++ E L+E + E N RE E ++ + +LE+
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
Query: 1185 STLQHEATAAALRKKHADSVA--ELGEQID-----SLQRVKQ----------KLEKEKSE 1227
A A ++KK DSV E E++ L+ + Q KLEK K+
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417
Query: 1228 LKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTE 1287
L+ E++DL +++ ++ N EK + + L+E KT + + A+ T+
Sbjct: 1418 LQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETK 1477
Query: 1288 SGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLL 1347
+ +R L+E ++L R + F ++E+L ++ K+ L + ++ + +
Sbjct: 1478 ALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEM 1537
Query: 1348 REQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEH 1407
+ Q EE ++ + + + + ++E D R E+ EE KK+L +++++ E
Sbjct: 1538 KTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597
Query: 1408 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEET 1467
+E + + +++L+ +++DL ++ +N K+ R + + ++ ++T
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
Query: 1468 QAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEG-GKH 1526
+A E +++ +L ++ + + L +R + QQE +L ++IA GK
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 1527 IHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKD 1584
LE+ K++L+ ++L+ LEE + + E ++ + L+++Q+ +++ +R A+K+
Sbjct: 1718 ALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 1585 EEL-DQLKRNHLRV---VESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQA 1640
E QL+R + + ++ M+ T+ ++ ++ AL K + ++E QL++ ++
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKER 1830
Query: 1641 AEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTE 1700
A + +R T+ LKD L +DD R + K+Q R ++ ++EE +R
Sbjct: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRAN 1890
Query: 1701 RGRKMAEQELLDASERVQLLHTQNTSLINTKKK 1733
R+ ++EL DA+E ++ + +SL N ++
Sbjct: 1891 ASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
Score = 228 bits (582), Expect = 3e-59
Identities = 207/985 (21%), Positives = 452/985 (45%), Gaps = 100/985 (10%)
Query: 997 TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056
TK K LQ + Q+ +++ +E+++ + + + E ++ ++E Q L K
Sbjct: 832 TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEMETLQSQ-------LMAEK 882
Query: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116
+L+ L+ E + E + +L K ++ E +L+ ++E+E+ LQ + K++Q
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1173
I+ELEE++E E ++R K + ++ +L+++ E LE+ + + ++ + R A
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 1174 EFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
EF + EE + + A L+ KH + +L E++ ++ +Q+LEK + +L+ +
Sbjct: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
Query: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
DL+ + + A + E++L + EE+ N + L ++ E
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
L+ + A ++ + K+ +++E LK +LE+ + + + ++L++ EE
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 1354 EQEAKA----ELQRGMSKANSEVAQW-----RTKYETDAIQRTEELEEAK-----KKLAQ 1399
E + E+++ S+A E+A+ R K + ++T E E + K L Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 1400 RLQDAEEHVEAVNSKCASL-------EKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452
D+E + V ++ L E+ + L ++V L ++++ D K
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 1453 FDKVLAEWKQKYEETQAELEASQKESRSLSTELFKV---KNAYEESLDHLETLKRENKNL 1509
K + + + ++TQ L+ ++ SLST+L +V KN++ E L+ E K NL
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH---NL 1355
Query: 1510 QQEISDLTEQIAEGGKHIHE-------LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKI 1562
+++I+ L Q+A+ K + + E+VK++L + L EE A+ + E
Sbjct: 1356 EKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTK 1415
Query: 1563 LRIQLELNQVKSEIDRK------IAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDAL 1616
R+Q EL+ + ++D + + +K ++ DQL + T+ A+ D
Sbjct: 1416 TRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE--------EKTISAKYAEERD-- 1465
Query: 1617 RIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLA 1676
+ E + E E + R EA+ + + K + ++D + +DD+ + +
Sbjct: 1466 ----RAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 1677 MVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
+E+ ++ +VEE++ LE E + L A+E + K +LE
Sbjct: 1522 ELEKSKRALEQQVEEMKTQLEELE--------DELQATE-------------DAKLRLEV 1560
Query: 1737 DISQIQGEME-DIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK 1795
++ ++ + E D+ +EEK K+ + M EL+ E+ + +K +E +K
Sbjct: 1561 NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK 1620
Query: 1796 DLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELT 1855
DL+ +D A + + KQ++KL+A++++ E++ + E + +++E+++K +
Sbjct: 1621 DLEAHIDSANKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSME 1679
Query: 1856 YQTEEDRKNIL-------RLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELE 1908
+ + ++ + + Q D+L ++ + A E+ A+ +L+ ELE
Sbjct: 1680 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1739
Query: 1909 EAKERADIAESQVNKLRVKSREVHT 1933
E + ++ ++ K ++ +++T
Sbjct: 1740 EEQGNTELINDRLKKANLQIDQINT 1764
Score = 182 bits (461), Expect = 4e-45
Identities = 189/889 (21%), Positives = 386/889 (43%), Gaps = 85/889 (9%)
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
+L K+K L ++ EEE+ A+ K +++ L E+ E L+ A Q++
Sbjct: 829 RLFTKVKPL-LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEM-ETLQSQLMAEKLQLQ 886
Query: 1167 MNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKS 1226
+ E E +L A A +++ + +L +++ + Q L+ EK
Sbjct: 887 EQLQAETELCAEAEELR-------ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK 939
Query: 1227 ELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE-----LSAQK 1281
+++ I +L +E A+ + LE +E K K+ E++++I E L+ +K
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQ-----LEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341
L EF+ L E++ L++ K I +L+ +L E K + L +
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE 1054
Query: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
D L +Q E Q AEL+ ++K E+ + E +A Q+ L++ ++ L ++
Sbjct: 1055 GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE-LESQI 1113
Query: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461
+ +E +E+ + EK K+ L E+E L ++E + + A + + ++ + K
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Query: 1462 QKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIA 1521
+ EE EA +E R K A EE + LE KR NL++ L +
Sbjct: 1174 KTLEEEAKTHEAQIQEMRQ------KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERG 1227
Query: 1522 EGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEE-------GKILRIQLELNQVK- 1573
E + L + K +H++ +++ L+E + E K+ ++Q+EL+ V
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTG 1287
Query: 1574 --SEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEI 1631
S+ D K ++ ++ L+ ++ Q L E R + K++E + N
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQ----LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 1632 QLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEE 1691
QL + + + D + ++D++ + +E +++ + EE
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 1692 LRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI--- 1748
A+ ++ E+ + +QEL D V L H Q S N +KK + Q+ E + I
Sbjct: 1404 KVAAYDKLEKTKTRLQQELDDLL--VDLDH-QRQSACNLEKK-QKKFDQLLAEEKTISAK 1459
Query: 1749 -VQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE-- 1805
+E AE +A++ T A +A L++ + A LER+ K ++DL D+
Sbjct: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 1806 ----QLALKGGKKQIQKLEARVRELESEVESEQ------KHNVEAVKGLRKHE------- 1848
+ + + ++Q+++++ ++ ELE E+++ + + N++A+K + +
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 1849 ---------RRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAK 1899
R+V+E+ + E++RK KL+ +K + + A + + + +
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Query: 1900 FRKLQHELEEAKERAD---------IAESQVNKLRVKSREVHTKVISEE 1939
RKLQ ++++ D +A+++ N+ ++KS E + EE
Sbjct: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
Score = 174 bits (441), Expect = 8e-43
Identities = 143/693 (20%), Positives = 314/693 (45%), Gaps = 30/693 (4%)
Query: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLE 920
+K + +L + + K E E L + LQ+++ L+ ++ + +L K LE
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALE 1307
Query: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE---KHATEN 977
+++++ E ++E L+ K +++EDE + ++ +++ E +EK+ HA
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367
Query: 978 KVKNLTEEMAGLDETIA----KLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033
+K E+ G ET KL K+ + L + H++ + + L K KT+L+Q
Sbjct: 1368 DMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-------AYDKLEKTKTRLQQ 1420
Query: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE--NDKQQLNEKLKKKEFEM 1091
++DDL L+ +++ +LE+ ++K D LA+E T+ + ++ + + ++KE +
Sbjct: 1421 ELDDLLVDLDHQRQSACNLEKKQKKF--DQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
Query: 1092 SNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1151
+L +E+ +L++ K+ + +E+L + S + EK + L +++EE+
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
Query: 1152 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQI 1211
+LEE A + + E Q M+ E + + +K+ V E+ ++
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
Query: 1212 DSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQ 1271
+ ++ + + +L+M++ DL +++++ +K + K R L+ Q+ + + ++ +
Sbjct: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658
Query: 1272 RLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKS 1331
E+ AQ + ++ + ++ R K+ Q+ +EL ++ + +
Sbjct: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
Query: 1332 TLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT--KYETDAIQRTE- 1388
+ L E+ EEEQ + + KAN ++ Q T E Q+ E
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 1389 ---ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIA 1445
+LE K+L +LQ+ E V++ AS+ + ++ E L + + AAC
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYK--ASITALEAKIAQLEEQLDNETKERQAAC-- 1834
Query: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505
K+ R +K L + + ++ + E + ++ ST L ++K EE+ + +
Sbjct: 1835 --KQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANAS 1892
Query: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLD 1538
+ LQ+E+ D TE + + L+ ++ D
Sbjct: 1893 RRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 114 bits (285), Expect = 9e-25
Identities = 118/579 (20%), Positives = 251/579 (43%), Gaps = 58/579 (10%)
Query: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMI 1434
WR + + + EE + L E A ++ +E + +L E L
Sbjct: 828 WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
Query: 1435 DVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494
++ C ++ + L KQ+ EE +LEA +E EE
Sbjct: 888 QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEARVEEE--------------EE 929
Query: 1495 SLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTS-LEEAEA 1553
HL+ E K +QQ I +L EQ+ E E + K QL+ +E + LEE +
Sbjct: 930 RCQHLQA---EKKKMQQNIQELEEQLEE-----EESARQKLQLEKVTTEAKLKKLEEEQI 981
Query: 1554 SLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE---LDQLKRNHLRVVESMQSTLDAEIR 1610
LE + K+ + + L +E + E++E+ L +LK H ++ ++ L E +
Sbjct: 982 ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEK 1041
Query: 1611 SRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDD 1670
R + + ++K+EGD ++ Q+ Q AE L + L+ +++ ++
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
Query: 1671 LKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQEL----------LDASERVQLL 1720
+++ +E + + +Q ++E RAS + E+ ++ +EL LD++ Q L
Sbjct: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161
Query: 1721 HTQNTSLINT-KKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779
++ +N KK LE + + +++++ Q+ A E+ +AE+L++ +
Sbjct: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE----------LAEQLEQTKRV 1211
Query: 1780 SAHLERMKKNMEQTVKDLQLRLDEAEQLALKG---GKKQIQKLEARVRELESEVESEQKH 1836
A+LE+ K QT+++ + L ++ L+G + + +K+EA+++EL+ + ++
Sbjct: 1212 KANLEKAK----QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
Query: 1837 NVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896
E + K + + +T + +L L+++++ + +E Q
Sbjct: 1268 RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSL 1327
Query: 1897 LAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKV 1935
K ++++ E +E+ + E + L + +H +V
Sbjct: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 1396 bits (3613), Expect = 0.0
Identities = 765/1924 (39%), Positives = 1190/1924 (61%), Gaps = 40/1924 (2%)
Query: 27 AQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKY 85
A + AK V++ + + A ++ G +V + E G V +D + MNPPK+
Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
Query: 86 DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRG 145
K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ ++ YRG
Sbjct: 85 SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + +
Sbjct: 145 KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
Query: 206 KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASAD 265
+K+ + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+
Sbjct: 205 RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
Query: 266 IETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPS 325
IETYLLEKSR Q K ER++HIFYQ+LS L LL+ ++ F+S G I +P
Sbjct: 261 IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
Query: 326 IDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385
D++ T A+ I+GF+ +E +++ K+ +V+ +GN+ FK+++ +QA VA
Sbjct: 320 QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
Query: 386 KAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTR 445
K +L +N + +++ PR+KVG ++V K QT +Q AV ALAKA YE++F W+V R
Sbjct: 380 KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
Query: 446 INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
IN+ LD TK+ FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 440 INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
Query: 505 KKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
++EGIEW FIDFG+DL CI+LIE+P G+ ++L+EEC FPKATD +F KL ++ G
Sbjct: 500 QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-G 558
Query: 562 KSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
+ FQKP+ K K A F ++HYAG VDY WL KN DPLN+ V L +S+ + +A
Sbjct: 559 SHSKFQKPRQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
Query: 622 FLFSGAQ--------TAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHF 673
L+ T E G KKG F+TV L++E+L KLM LR+T+P+F
Sbjct: 617 ELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNF 675
Query: 674 VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASA 733
VRCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L +A
Sbjct: 676 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
Query: 734 IPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQ 793
IP+G F+D K+A E+++ ++E+D Y+ G +K+FF+AG+L LEE RD K+ +I Q
Sbjct: 736 IPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQ 794
Query: 794 AICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEM 853
A+CRG+L R F K ++ ++ +Q N A++ ++HW W +++ K+KPLL+ E+E+
Sbjct: 795 AVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEEL 854
Query: 854 ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLI 913
EE K KE+ K E + +E+E K L++EKN L Q+QAE + A+AEE +L
Sbjct: 855 QAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLA 914
Query: 914 KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973
K +LE + ++ R E+EEE N L +K+K++ +L++ +D+ E K++ EK
Sbjct: 915 AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033
E K+K + EE+ L++ +K KEKK +++ + L EE+K L K + K E
Sbjct: 975 TAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEV 1034
Query: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSN 1093
+ DLE L++E+K +LE+AKRKL+G+ Q+ + + +L +L KKE E+
Sbjct: 1035 MISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 1094 LQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER 1153
+ +DE K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE +
Sbjct: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
Query: 1154 LEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDS 1213
LE+ T+AQ E+ KRE E ++++ LEE T HEA +R++HA ++ EL EQ++
Sbjct: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
Query: 1214 LQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRL 1273
+R K LEK K L+ + +LA ++ + + KA E + L+ Q+ E+ K E RL
Sbjct: 1215 AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
Query: 1274 INELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTL 1333
EL+ + ++L E S L+E + + ++ + Q+++ + L+EET+ K L
Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
Query: 1334 AHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEA 1393
+ ++ + + L+EQ EEE+EA+ L++ + S++A + K + D + E LEEA
Sbjct: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEA 1393
Query: 1394 KKKLAQRLQDAEEHVEAVNSKCAS---LEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450
KKKL L+DAE + + K + LEKTK RLQ E++DL +D++ L+KKQ
Sbjct: 1394 KKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450
Query: 1451 RNFDKVLAEWKQ---KY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505
+ FD++LAE K +Y E +AE EA +KE+++LS + A EE+L+ E +R+
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS-----LARALEEALEAKEEFERQ 1505
Query: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
NK L+ ++ DL + GK++HELEK K+ L+ + E++T LEE E L+ E LR+
Sbjct: 1506 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRL 1565
Query: 1566 QLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGD 1625
++ + +K++ +R + +DE+ ++ KR ++ V +++ L+ E + R A+ KKKME D
Sbjct: 1566 EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEID 1625
Query: 1626 LNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLM 1685
L ++E Q+ AN+ E ++ LR Q +KD Q L++A +D++ Q E++ +
Sbjct: 1626 LKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSL 1685
Query: 1686 QAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEM 1745
+AE+ +L+ L +ER R+ AEQE + ++ + + ++L++ K++LE I+Q++ E+
Sbjct: 1686 EAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 1746 EDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE 1805
E+ ++ +K + EL E+ + + ++ +E+ K+L+ +L E E
Sbjct: 1746 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
Query: 1806 QLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNI 1865
K I LEA++ +LE ++E E K A K +R+ E+++KE+ Q E++R++
Sbjct: 1806 GAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHA 1865
Query: 1866 LRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLR 1925
+ ++ ++K ++K KRQ EEAEE++ A RKLQ EL++A E + +V+ L+
Sbjct: 1866 DQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLK 1925
Query: 1926 VKSR 1929
+ R
Sbjct: 1926 NRLR 1929
Score = 249 bits (637), Expect = 1e-65
Identities = 258/1124 (22%), Positives = 500/1124 (44%), Gaps = 155/1124 (13%)
Query: 718 LYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTL 777
L A ++ KV EG+ + ++ ++LL I Q + T++F +A
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ-AETELFAEA------ 906
Query: 778 EEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLY 837
EEMR +LA + I RVE E R I N K K+
Sbjct: 907 EEMR-ARLAAKKQELEEILHDLESRVEEE---EERNQIL---------QNEKK----KMQ 949
Query: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTL-------MQEKND 890
I+ L + + E+E A K + EK EAK K++EE+++ L ++EK
Sbjct: 950 AHIQDLEEQLD-EEEGARQKLQLEKVT-----AEAKIKKMEEEILLLEDQNSKFIKEKKL 1003
Query: 891 LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-- 948
++ ++ + LA+ EE+ L K + + E I ++ ER + EE+ EL KRKL+
Sbjct: 1004 MEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGE 1063
Query: 949 -----DECSELKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGL 989
D+ +EL+ ID+L+L LAK E+E K+ V+ L ++A L
Sbjct: 1064 TTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL 1123
Query: 990 DETIA-------KLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
E K K+K+ L E + +L+ D + +TK EQ+V +L+ +L
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 1043 EQE-----------------------------KKLCMDLERAKRKLEGDLKLAQESTMDT 1073
E+E K+ +LE+ K+ LE D K
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 1074 ENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASR 1133
+ K + K KK + ++ L K+ + L ++L +K +LQ ++ + +E
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 1134 AKAEKQRSDLSRELEEISERLEEAGGAT---SAQIEMNKKREAEFQKMRRDLEESTLQHE 1190
K K + L +L++ E L+E S++I ++ + Q+ + + EE+ E
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
Query: 1191 ATAAALRKKHADSVAELGEQ---IDSLQRVKQKL---------------------EKEKS 1226
AL+ + AD+ ++ + I+SL+ K+KL EK K+
Sbjct: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Query: 1227 ELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHT 1286
L+ E++DL +++ + +N EK + + L+E K+ + A+ T
Sbjct: 1424 RLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 1287 ESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK-------RQLEEETKAKSTLAHALQS 1339
++ +R L+E + R + +E+L + + E K+K L ++
Sbjct: 1484 KALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543
Query: 1340 ARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1399
R + L ++ + ++AK L+ M ++ +E D R E+ EE K+ L +
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQ-------FERDLQTRDEQNEEKKRLLIK 1596
Query: 1400 RLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAE 1459
++++ E +E + A +K++++ +++DL +E +N A + K+ R + +
Sbjct: 1597 QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656
Query: 1460 WKQKYEETQA---ELEASQKES----RSLSTELFKVKNAYEESLDHLETLKRENKNLQQE 1512
++++ EE +A E+ A KES +SL E+ +++ + L + +R ++ +QE
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQE 1709
Query: 1513 ISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQV 1572
+L ++I L K++L+ ++L+ LEE ++++E + + L+++ +
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 1573 KSEI--DRKIAEK-DEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEM 1629
+E+ +R A+K D QL+R + + +Q L+ ++S+ A +E + ++
Sbjct: 1770 NAELAAERSAAQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATI--SALEAKIGQL 1826
Query: 1630 EIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV 1689
E QL ++ A A + +R T+ LK+ + ++D R D KEQ+ R ++ ++
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
Query: 1690 EELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKK 1733
EE R R+ ++EL DA+E + L + ++L N ++
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Score = 191 bits (484), Expect = 8e-48
Identities = 191/883 (21%), Positives = 400/883 (45%), Gaps = 81/883 (9%)
Query: 1111 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS---ERLEEAGGATSAQIEM 1167
K+K L ++ EEE++A+ K +++++ + ELEE+ ++L E + Q++
Sbjct: 840 KVKPL-LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA 898
Query: 1168 NKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSE 1227
+ AE ++MR A AA +++ + + +L +++ + Q L+ EK +
Sbjct: 899 ETELFAEAEEMR-----------ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKK 947
Query: 1228 LKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE-----LSAQKA 1282
++ I DL ++ A+ + LE +E K K+ E++ L+ E +K
Sbjct: 948 MQAHIQDLEEQLDEEEGARQKLQ-----LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 1283 RLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARH 1342
+ E S QL E++ L++ + I +L+ +L++E K + L A +
Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
Query: 1343 DCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1402
+ L++Q E Q EL+ ++K E+ + + + + + L+ ++ AQ +
Sbjct: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ-IA 1121
Query: 1403 DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQ 1462
+ +E E+ + EK K+ L E+E L ++E + A + + ++ +AE K+
Sbjct: 1122 ELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKK 1181
Query: 1463 KYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAE 1522
EE EA ++ R + A EE + LE KR NL++ L E
Sbjct: 1182 ALEEETKNHEAQIQDMRQ------RHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE 1235
Query: 1523 GGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQL--ELNQVKSEIDRKI 1580
+ L++VK + +H++ +L ++E A + EG LR++L + +++++E+D +
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVELAEKASKLQNELDN-V 1292
Query: 1581 AEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQA 1640
+ EE ++ + S++S L + R K + + ++E + N Q
Sbjct: 1293 STLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQ 1352
Query: 1641 AE---ALRNLRNT----QGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELR 1693
E A +NL Q L DT+ +DD + + L+E + + A + +EE
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA 1412
Query: 1694 ASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEAR 1753
+ ++ E+ + +QEL D + + ++L +KK + +++ + +E
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QL 1807
AE +A++ T A +A L++ + ER K + ++DL D+ +
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 1808 ALKGGKKQIQKLEARVRELESEVESEQ------KHNVEAVKGLRKHE------------- 1848
+ + ++Q++++ ++ ELE E+++ + + N++A+K + +
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 1849 ---RRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQ- 1904
++V+EL + E++RK K++ +K + Q E A + + + + RKLQ
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 1905 ------HELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
ELEEA+ D A+S+ ++ ++KS E + EE
Sbjct: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
Score = 173 bits (439), Expect = 1e-42
Identities = 164/737 (22%), Positives = 339/737 (45%), Gaps = 59/737 (8%)
Query: 854 ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLI 913
A + + +K ++ + AK E + V L ++ + LQ ++ + L +AE++ +
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 914 KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973
K LE+++++ E ++E L+++ R+LE+E + L++ ++ E +EK+
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDDLQMEEDKVNTLTKAKTK 1030
A ++++ + +++ TI L + KK L EA Q L++ + DK L K K +
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK---LEKTKNR 1424
Query: 1031 LEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE--NDKQQLNEKLKKKE 1088
L+Q++DDL L+ ++++ +LE+ ++K D LA+E ++ ++ + + ++KE
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYAEERDRAEAEAREKE 1482
Query: 1089 FEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
+ +L +E+ + +++ K+L+A +E+L + + + EK + L +++E
Sbjct: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE 1542
Query: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEESTLQHEATAAALRKKHADSV 1204
E+ +LEE A + + E Q M+ RDL+ Q+E L K+ V
Sbjct: 1543 EMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ----V 1598
Query: 1205 AELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264
EL +++ ++ + K ++++++ DL + +E +KA+ K R L+ Q+
Sbjct: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM---- 1654
Query: 1265 TKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLS-------RGKQAFTQQIE 1317
++ QR + E A + + +S E ++L +A + QL R ++ Q+ +
Sbjct: 1655 ---KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERD 1711
Query: 1318 ELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT 1377
EL ++ KS L + L E+ EEEQ L K +V
Sbjct: 1712 ELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNA 1771
Query: 1378 KY--ETDAIQRTE----ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431
+ E A Q+++ +LE K+L +LQ+ E AV SK + T L+ ++
Sbjct: 1772 ELAAERSAAQKSDNARQQLERQNKELKAKLQELEG---AVKSK---FKATISALEAKIGQ 1825
Query: 1432 LMIDVERSNAACIALDKKQRNFDKVLAE--------------WKQKYEETQAELEASQKE 1477
L +E+ A +K R +K L E +K++ E+ A ++ +++
Sbjct: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
Query: 1478 SRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGK-HIHELEKVKKQ 1536
E + + + L+ N+ L +E+S L ++ GG ++Q
Sbjct: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQ 1945
Query: 1537 LDHEKSELQTSLEEAEA 1553
L E + L+ S ++ E+
Sbjct: 1946 LHLEGASLELSDDDTES 1962
Score = 119 bits (298), Expect = 3e-26
Identities = 111/489 (22%), Positives = 225/489 (46%), Gaps = 19/489 (3%)
Query: 844 LKSAETEKEMANMKEEFEKTKEEL-AKTE---AKRKELEEKMVTLMQEKNDLQLQVQAEA 899
L A +E KEEFE+ ++L A E + + ++ + + L + K L+ QV+
Sbjct: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
Query: 900 DALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTA-KKRKLEDECSELKKDI 958
L + E+ K++LE ++ + + E + + E KKR L + EL+ ++
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1605
Query: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ---EAHQQTLDDLQ 1015
+D A K E +K+L ++ ++ ++ K+ + LQ + +Q+ L++ +
Sbjct: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
Query: 1016 MEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL-KLAQESTMDTE 1074
D++ +K E+++ LE + Q ++ ERA+R E + +LA E T
Sbjct: 1666 ASRDEIFAQSKES---EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSAS 1722
Query: 1075 NDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRA 1134
L+EK ++ E ++ L+ ++E+EQ+ L + ++ +++ L E+ AER++
Sbjct: 1723 GKSALLDEK-RRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ 1781
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMN-KKREAEFQKMRRDLEESTLQHEATA 1193
K++ R L R+ +E+ +L+E GA ++ + EA+ ++ LE+ + A A
Sbjct: 1782 KSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA-KERAAA 1840
Query: 1194 AALRKKHADSVAELGEQIDSLQR----VKQKLEKEKSELKMEINDLASNMETVSKAKANF 1249
L ++ + E+ Q++ +R K+++EK + +K L E ++A A+
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGK 1309
K+ R L+D + E L N L + S RQL + A +
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDT 1960
Query: 1310 QAFTQQIEE 1318
++ T + E
Sbjct: 1961 ESKTSDVNE 1969
Score = 75.9 bits (185), Expect = 4e-13
Identities = 77/346 (22%), Positives = 157/346 (45%), Gaps = 15/346 (4%)
Query: 1591 KRNHLRVVESMQSTLDAEIRSRN-DALRIKKKMEG--DLNEMEIQLNHANRQAAEALRNL 1647
K+ L ++ +Q A ++ R+ R+ K++ + E +L + + +
Sbjct: 809 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ 868
Query: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE 1707
+G L++ + + ++ L EQL + + AE EE+RA L ++ E
Sbjct: 869 TKVEGELEEMERKHQQLLEEKNILAEQL----QAETELFAEAEEMRARLAAK---KQELE 921
Query: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA 1767
+ L D RV+ +N L N KKK++ I ++ ++++ +E + + +K +A
Sbjct: 922 EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE--EEGARQKLQLEKVTAEAK 979
Query: 1768 M--MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRE 1825
+ M EE+ +D ++ + KK ME + + +L E E+ A K K K E + +
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA-KNLAKIRNKQEVMISD 1038
Query: 1826 LESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885
LE ++ E+K E K RK + +L Q E + I L+ + K + +++ +
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 1886 AEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
++ N L R+LQ ++ E +E + ++ NK + R++
Sbjct: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDL 1144
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 1285 bits (3326), Expect = 0.0
Identities = 707/1900 (37%), Positives = 1141/1900 (60%), Gaps = 25/1900 (1%)
Query: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99
P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E
Sbjct: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
Query: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159
+VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++
Sbjct: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
Query: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTL 219
+ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + K ++EP + G L
Sbjct: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA-SSPKGRKEPG---VPGEL 234
Query: 220 EDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQ 279
E Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR Q
Sbjct: 235 ERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQ 294
Query: 280 LKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAV 339
K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T ++
Sbjct: 295 AKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESL 352
Query: 340 DILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLL 399
+LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L D
Sbjct: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412
Query: 400 KSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQ-- 457
++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + PRQ
Sbjct: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGA 471
Query: 458 YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFG 517
F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG
Sbjct: 472 SFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFG 531
Query: 518 MDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKG 574
+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+ +
Sbjct: 532 LDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRHLRD 590
Query: 575 KPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQ-----T 629
+A FS++HYAG VDY WL KN DPLN+ V L +S + A ++ +
Sbjct: 591 --QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLE 648
Query: 630 AEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAME 689
+ G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN K G +E
Sbjct: 649 QVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLE 708
Query: 690 HELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKL 749
LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK+
Sbjct: 709 PRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKM 767
Query: 750 LGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMM 809
+ ++E+D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L R F+K
Sbjct: 768 IQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQ 827
Query: 810 ERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAK 869
+++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E +
Sbjct: 828 QQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQ 887
Query: 870 TEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTER 929
+ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE + E+ R
Sbjct: 888 SAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEAR 947
Query: 930 AEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
+EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E++ L
Sbjct: 948 VGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLL 1007
Query: 990 DETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLC 1049
++ +KL+KE+K L++ + EE+KV +L K + K E + D+E L +E+K
Sbjct: 1008 EDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGR 1067
Query: 1050 MDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQ 1109
+LE+ KR+L+G+ QE ++ + ++L +L +KE E+ + EDE QL
Sbjct: 1068 QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1127
Query: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169
K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+
Sbjct: 1128 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1187
Query: 1170 KREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELK 1229
KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK + L+
Sbjct: 1188 KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALE 1247
Query: 1230 MEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG 1289
E+++L + + ++ A+ E+ R LE QL E++ + + +R E + + R E
Sbjct: 1248 AEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELE 1307
Query: 1290 EFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLRE 1349
S L+E ++ +LS+ + Q+ + + L+EET+AK L +++ + LRE
Sbjct: 1308 NVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLRE 1367
Query: 1350 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE 1409
Q EEE A+ R + A +++++WR + E +A E EEA+++ A+ + + +
Sbjct: 1368 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLA 1426
Query: 1410 AVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA 1469
LE+ ++RLQ E++D +D+E+ L+KKQR FD++LAE K
Sbjct: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486
Query: 1470 ELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHE 1529
E E ++ E R + A EE + E L+R+N+ L+ E+ L + GK +HE
Sbjct: 1487 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1546
Query: 1530 LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ 1589
LE+ + + ++L+ + E E L E LR+++ + +K++ +R + +DE ++
Sbjct: 1547 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEE 1606
Query: 1590 LKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRN 1649
+R + + + D E + R A+ +KK+EG+L E++ Q+ A + EA++ LR
Sbjct: 1607 RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1666
Query: 1650 TQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709
Q +K+ +++ ++++ Q E+R ++AEV L+ L ++R R+ A+Q+
Sbjct: 1667 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQD 1726
Query: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMM 1769
+ ++ V + +++ K++LE + Q++ E+E+ + ++ +K + +
Sbjct: 1727 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1786
Query: 1770 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESE 1829
EL E+ SA E ++ +E+ +++L+ RL E + A K I LE+++ + E +
Sbjct: 1787 TTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1846
Query: 1830 VESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEA 1889
+E E + + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ EEA
Sbjct: 1847 LEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1906
Query: 1890 EEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
EE+++ A R+LQ ELE+ E A+ +V LR + R
Sbjct: 1907 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
Score = 241 bits (615), Expect = 5e-63
Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097
Query: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214
Query: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L
Sbjct: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274
Query: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++
Sbjct: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394
Query: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
R EE EA A R+ ++ +AE E +D L+R +++L++E + M++
Sbjct: 1395 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1454
Query: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
+ T+ K + F+++ L ++ + + EE++R E ++AR + +R
Sbjct: 1455 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1507
Query: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E
Sbjct: 1508 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1567
Query: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
++ + + V +T++E D R E EE +++LA++L+DAE +
Sbjct: 1568 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1627
Query: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1628 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1687
Query: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
++R L ++ + L R + QQ+ ++ +++A G + +
Sbjct: 1688 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1747
Query: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591
K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1748 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1807
Query: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
++ + DA R+R+ +E L + E QL R+ + + +R +
Sbjct: 1808 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1865
Query: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL
Sbjct: 1866 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1925
Query: 1712 DASERVQLLHTQNTSLINTKKK 1733
D +E + ++ + T+L N ++
Sbjct: 1926 DVTESAESMNREVTTLRNRLRR 1947
Score = 169 bits (429), Expect = 2e-41
Identities = 187/885 (21%), Positives = 388/885 (43%), Gaps = 85/885 (9%)
Query: 1106 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
+Q+ ++ + LQAR +EL++ E ++ S +RE+ E+ R+ AQ+
Sbjct: 862 LQVTRQDEVLQARAQELQKVQELQQQS-----------AREVGELQGRV--------AQL 902
Query: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEK 1225
E + R AE + +L + AA +++ V+EL ++ + ++++ EK
Sbjct: 903 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 962
Query: 1226 SELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE-----LSAQ 1280
L+ I +L +++E A+ + LE +E K K+ E+ L+ E LS +
Sbjct: 963 KRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1017
Query: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340
+ L EFS Q E++ V L++ + + I +++ +L +E K + L +
Sbjct: 1018 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1077
Query: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ L+EQ E+Q+ EL+ + + E+ + E + R + L+ ++ A
Sbjct: 1078 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAA- 1136
Query: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460
L +A+E +E+ EK ++ L E+E L ++E + + A + + ++ + E
Sbjct: 1137 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1196
Query: 1461 KQKYEETQAELEASQKESRSLSTE-LFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQ 1519
K+ EE EA+ +E R + L ++ E++ ++ L+ E+S+L +
Sbjct: 1197 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1256
Query: 1520 IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK---SEI 1576
++ E E+ +++L+ + E+Q + E + K+ R Q EL V +E
Sbjct: 1257 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEA 1316
Query: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
+ K +EL + + Q L E R++ + ME + + QL
Sbjct: 1317 ESKTIRLSKELSSTEAQ----LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1372
Query: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
A R L+ Q L + + ++ + +E R A + + E ++
Sbjct: 1373 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1432
Query: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIV----QEA 1752
+R ERGR+ +QEL DA+ ++ Q L++T +K + Q+ E + V +E
Sbjct: 1433 DRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1488
Query: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM---------------------- 1790
AE + ++ A + L++EQ+ LER + +
Sbjct: 1489 ERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1548
Query: 1791 ------EQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGL 1844
EQ DL+ ++ E E L + +LE V+ L+++ E + + EA +
Sbjct: 1549 RACRVAEQAANDLRAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1607
Query: 1845 RKH-ERRVKELTYQTEEDRKNIL-------RLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896
R+ +++++ + +E+RK +L+ +++L+ ++ + + EEA +Q
Sbjct: 1608 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667
Query: 1897 LAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
A+ ++L E+EE + + ++++ ++ R+K E + EE
Sbjct: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 1285 bits (3325), Expect = 0.0
Identities = 709/1904 (37%), Positives = 1142/1904 (59%), Gaps = 25/1904 (1%)
Query: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99
P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E
Sbjct: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
Query: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159
+VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++
Sbjct: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
Query: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEE--PASGKM-- 215
+ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE PAS
Sbjct: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVS 238
Query: 216 QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 275
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 239 YGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 298
Query: 276 VTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMAT 335
Q K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T
Sbjct: 299 AIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQET 356
Query: 336 DSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNS 395
++ +LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L
Sbjct: 357 LESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGV 416
Query: 396 ADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQP 455
D ++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + P
Sbjct: 417 TDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSP 475
Query: 456 RQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEF 513
RQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F
Sbjct: 476 RQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 535
Query: 514 IDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570
+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+
Sbjct: 536 LDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPR 594
Query: 571 PAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQ-- 628
+ +A FS++HYAG VDY WL KN DPLN+ V L +S + A ++ +
Sbjct: 595 HLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGI 652
Query: 629 ---TAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTP 685
+ G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN K
Sbjct: 653 VGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRA 712
Query: 686 GAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA 745
G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A
Sbjct: 713 GKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA 771
Query: 746 SEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEF 805
EK++ ++E+D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L R F
Sbjct: 772 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 831
Query: 806 RKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKE 865
+K +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E
Sbjct: 832 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 891
Query: 866 ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKE 925
++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE + E
Sbjct: 892 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 951
Query: 926 VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E+
Sbjct: 952 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1011
Query: 986 MAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1045
+ L++ +KL+KE+K L++ + EE+KV +L K + K E + D+E L +E
Sbjct: 1012 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1071
Query: 1046 KKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALA 1105
+K +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ + EDE
Sbjct: 1072 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
Query: 1106 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ
Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1191
Query: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEK 1225
E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK +
Sbjct: 1192 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
Query: 1226 SELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLH 1285
L+ E+++L + + ++ A+ E+ R LE QL E++ + + +R E + + R
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
Query: 1286 TESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCD 1345
E S L+E ++ +LS+ + Q+ + + L+EET+AK L +++ +
Sbjct: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
Query: 1346 LLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405
LREQ EEE A+ R + A +++++WR + E +A E EEA+++ A+ +
Sbjct: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALT 1430
Query: 1406 EHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYE 1465
+ + LE+ ++RLQ E++D +D+E+ L+KKQR FD++LAE K
Sbjct: 1431 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
Query: 1466 ETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGK 1525
E E ++ E R + A EE + E L+R+N+ L+ E+ L + GK
Sbjct: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1550
Query: 1526 HIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDE 1585
+HELE+ + + ++L+ + E E L E LR+++ + +K++ +R + +DE
Sbjct: 1551 SVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE 1610
Query: 1586 ELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR 1645
++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + EA++
Sbjct: 1611 AGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVK 1670
Query: 1646 NLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKM 1705
LR Q +K+ +++ ++++ Q E+R ++AEV L+ L ++R R+
Sbjct: 1671 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQ 1730
Query: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITD 1765
A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +K +
Sbjct: 1731 AQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQ 1790
Query: 1766 AAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRE 1825
+ EL E+ SA E ++ +E+ +++L+ RL E + A K I LE+++ +
Sbjct: 1791 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 1850
Query: 1826 LESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885
E ++E E + + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ
Sbjct: 1851 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1910
Query: 1886 AEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
EEAEE+++ A R+LQ ELE+ E A+ +V LR + R
Sbjct: 1911 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
Score = 241 bits (615), Expect = 5e-63
Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
Query: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222
Query: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L
Sbjct: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282
Query: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++
Sbjct: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402
Query: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
R EE EA A R+ ++ +AE E +D L+R +++L++E + M++
Sbjct: 1403 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1462
Query: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
+ T+ K + F+++ L ++ + + EE++R E ++AR + +R
Sbjct: 1463 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1515
Query: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E
Sbjct: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575
Query: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
++ + + V +T++E D R E EE +++LA++L+DAE +
Sbjct: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635
Query: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695
Query: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
++R L ++ + L R + QQ+ ++ +++A G + +
Sbjct: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755
Query: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591
K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815
Query: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
++ + DA R+R+ +E L + E QL R+ + + +R +
Sbjct: 1816 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1873
Query: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL
Sbjct: 1874 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1933
Query: 1712 DASERVQLLHTQNTSLINTKKK 1733
D +E + ++ + T+L N ++
Sbjct: 1934 DVTESAESMNREVTTLRNRLRR 1955
Score = 169 bits (429), Expect = 2e-41
Identities = 187/885 (21%), Positives = 388/885 (43%), Gaps = 85/885 (9%)
Query: 1106 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
+Q+ ++ + LQAR +EL++ E ++ S +RE+ E+ R+ AQ+
Sbjct: 870 LQVTRQDEVLQARAQELQKVQELQQQS-----------AREVGELQGRV--------AQL 910
Query: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEK 1225
E + R AE + +L + AA +++ V+EL ++ + ++++ EK
Sbjct: 911 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 970
Query: 1226 SELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE-----LSAQ 1280
L+ I +L +++E A+ + LE +E K K+ E+ L+ E LS +
Sbjct: 971 KRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1025
Query: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340
+ L EFS Q E++ V L++ + + I +++ +L +E K + L +
Sbjct: 1026 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1085
Query: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ L+EQ E+Q+ EL+ + + E+ + E + R + L+ ++ A
Sbjct: 1086 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAA- 1144
Query: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460
L +A+E +E+ EK ++ L E+E L ++E + + A + + ++ + E
Sbjct: 1145 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1204
Query: 1461 KQKYEETQAELEASQKESRSLSTE-LFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQ 1519
K+ EE EA+ +E R + L ++ E++ ++ L+ E+S+L +
Sbjct: 1205 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1264
Query: 1520 IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK---SEI 1576
++ E E+ +++L+ + E+Q + E + K+ R Q EL V +E
Sbjct: 1265 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEA 1324
Query: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
+ K +EL + + Q L E R++ + ME + + QL
Sbjct: 1325 ESKTIRLSKELSSTEAQ----LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
Query: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
A R L+ Q L + + ++ + +E R A + + E ++
Sbjct: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440
Query: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIV----QEA 1752
+R ERGR+ +QEL DA+ ++ Q L++T +K + Q+ E + V +E
Sbjct: 1441 DRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1496
Query: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM---------------------- 1790
AE + ++ A + L++EQ+ LER + +
Sbjct: 1497 ERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1556
Query: 1791 ------EQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGL 1844
EQ DL+ ++ E E L + +LE V+ L+++ E + + EA +
Sbjct: 1557 RACRVAEQAANDLRAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1615
Query: 1845 RKH-ERRVKELTYQTEEDRKNIL-------RLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896
R+ +++++ + +E+RK +L+ +++L+ ++ + + EEA +Q
Sbjct: 1616 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675
Query: 1897 LAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
A+ ++L E+EE + + ++++ ++ R+K E + EE
Sbjct: 1676 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 1276 bits (3301), Expect = 0.0
Identities = 713/1937 (36%), Positives = 1143/1937 (59%), Gaps = 58/1937 (2%)
Query: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99
P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E
Sbjct: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
Query: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159
+VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++
Sbjct: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
Query: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEE--PASGKM-- 215
+ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE PAS
Sbjct: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVS 238
Query: 216 QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 275
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 239 YGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 298
Query: 276 VTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMAT 335
Q K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T
Sbjct: 299 AIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQET 356
Query: 336 DSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNS 395
++ +LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L
Sbjct: 357 LESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGV 416
Query: 396 ADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQP 455
D ++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + P
Sbjct: 417 TDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSP 475
Query: 456 RQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEF 513
RQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F
Sbjct: 476 RQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 535
Query: 514 IDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570
+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+
Sbjct: 536 LDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPR 594
Query: 571 PAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA--------- 621
+ +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 595 HLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGG 652
Query: 622 ---FLFSGAQTAEAEG--------------------------GGGKKGGKKKGSSFQTVS 652
F F G+ G G G GG+ + F+TV
Sbjct: 653 FQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVG 712
Query: 653 ALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKG 712
L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEGIRICR+G
Sbjct: 713 QLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQG 772
Query: 713 FPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAG 772
FP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++E+D Y+ G +K+FF+AG
Sbjct: 773 FPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAG 831
Query: 773 LLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWP 832
+L LEE RD K+ +I QA RG+L R F+K +++ ++ +Q N A++ ++HW
Sbjct: 832 VLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQ 891
Query: 833 WMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892
W +L+ K+KPLL+ ++ + +E +K +E ++ + EL+ ++ L +E+ L
Sbjct: 892 WWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLA 951
Query: 893 LQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 952
Q++AEA+ A+AEE +L K +LE + E+ R +EEE + ++ +K++L+
Sbjct: 952 EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQ 1011
Query: 953 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++ +
Sbjct: 1012 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSS 1071
Query: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072
EE+KV +L K + K E + D+E L +E+K +LE+ KR+L+G+ QE ++
Sbjct: 1072 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVE 1131
Query: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERAS 1132
+ ++L +L +KE E+ + EDE QL K ++E QA + E +E++E+ER +
Sbjct: 1132 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
Query: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEAT 1192
R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T HEA
Sbjct: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
Query: 1193 AAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKM 1252
LR++H ++ EL EQ++ +R K EK + L+ E+++L + + ++ A+ E+
Sbjct: 1252 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1311
Query: 1253 CRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAF 1312
R LE QL E++ + + +R E + + R E S L+E ++ +LS+ +
Sbjct: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
Query: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEV 1372
Q+ + + L+EET+AK L +++ + LREQ EEE A+ R + A +++
Sbjct: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1431
Query: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDL 1432
++WR + E +A E EEA+++ A+ + + + LE+ ++RLQ E++D
Sbjct: 1432 SEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDA 1490
Query: 1433 MIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY 1492
+D+E+ L+KKQR FD++LAE K E E ++ E R + A
Sbjct: 1491 TMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1550
Query: 1493 EESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAE 1552
EE + E L+R+N+ L+ E+ L + GK +HELE+ + + ++L+ + E E
Sbjct: 1551 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1610
Query: 1553 ASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSR 1612
L E LR+++ + +K++ +R + +DE ++ +R + + + D E + R
Sbjct: 1611 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1670
Query: 1613 NDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLK 1672
A+ +KK+EG+L E++ Q+ A + EA++ LR Q +K+ +++ ++++
Sbjct: 1671 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1730
Query: 1673 EQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKK 1732
Q E+R ++AEV L+ L ++R R+ A+Q+ + ++ V + +++ K+
Sbjct: 1731 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1790
Query: 1733 KLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1792
+LE + Q++ E+E+ + ++ +K + + EL E+ SA E ++ +E+
Sbjct: 1791 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850
Query: 1793 TVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVK 1852
+++L+ RL E + A K I LE+++ + E ++E E + + + K +R+ E+R+K
Sbjct: 1851 QIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 1910
Query: 1853 ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKE 1912
E+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ A R+LQ ELE+ E
Sbjct: 1911 EVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTE 1970
Query: 1913 RADIAESQVNKLRVKSR 1929
A+ +V LR + R
Sbjct: 1971 SAESMNREVTTLRNRLR 1987
Score = 241 bits (615), Expect = 5e-63
Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)
Query: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
Query: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
Query: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255
Query: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L
Sbjct: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315
Query: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119
E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++
Sbjct: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375
Query: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435
Query: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
R EE EA A R+ ++ +AE E +D L+R +++L++E + M++
Sbjct: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1495
Query: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
+ T+ K + F+++ L ++ + + EE++R E ++AR + +R
Sbjct: 1496 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1548
Query: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E
Sbjct: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608
Query: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
++ + + V +T++E D R E EE +++LA++L+DAE +
Sbjct: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668
Query: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728
Query: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
++R L ++ + L R + QQ+ ++ +++A G + +
Sbjct: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788
Query: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591
K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848
Query: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
++ + DA R+R+ +E L + E QL R+ + + +R +
Sbjct: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906
Query: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL
Sbjct: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966
Query: 1712 DASERVQLLHTQNTSLINTKKK 1733
D +E + ++ + T+L N ++
Sbjct: 1967 DVTESAESMNREVTTLRNRLRR 1988
Score = 169 bits (429), Expect = 2e-41
Identities = 187/885 (21%), Positives = 388/885 (43%), Gaps = 85/885 (9%)
Query: 1106 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
+Q+ ++ + LQAR +EL++ E ++ S +RE+ E+ R+ AQ+
Sbjct: 903 LQVTRQDEVLQARAQELQKVQELQQQS-----------AREVGELQGRV--------AQL 943
Query: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEK 1225
E + R AE + +L + AA +++ V+EL ++ + ++++ EK
Sbjct: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
Query: 1226 SELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE-----LSAQ 1280
L+ I +L +++E A+ + LE +E K K+ E+ L+ E LS +
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1058
Query: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340
+ L EFS Q E++ V L++ + + I +++ +L +E K + L +
Sbjct: 1059 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1118
Query: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
+ L+EQ E+Q+ EL+ + + E+ + E + R + L+ ++ A
Sbjct: 1119 DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAA- 1177
Query: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460
L +A+E +E+ EK ++ L E+E L ++E + + A + + ++ + E
Sbjct: 1178 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1237
Query: 1461 KQKYEETQAELEASQKESRSLSTE-LFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQ 1519
K+ EE EA+ +E R + L ++ E++ ++ L+ E+S+L +
Sbjct: 1238 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1297
Query: 1520 IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK---SEI 1576
++ E E+ +++L+ + E+Q + E + K+ R Q EL V +E
Sbjct: 1298 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEA 1357
Query: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
+ K +EL + + Q L E R++ + ME + + QL
Sbjct: 1358 ESKTIRLSKELSSTEAQ----LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1413
Query: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
A R L+ Q L + + ++ + +E R A + + E ++
Sbjct: 1414 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1473
Query: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIV----QEA 1752
+R ERGR+ +QEL DA+ ++ Q L++T +K + Q+ E + V +E
Sbjct: 1474 DRLERGRRRLQQELDDATMDLE----QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1529
Query: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM---------------------- 1790
AE + ++ A + L++EQ+ LER + +
Sbjct: 1530 ERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELE 1589
Query: 1791 ------EQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGL 1844
EQ DL+ ++ E E L + +LE V+ L+++ E + + EA +
Sbjct: 1590 RACRVAEQAANDLRAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
Query: 1845 RKH-ERRVKELTYQTEEDRKNIL-------RLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896
R+ +++++ + +E+RK +L+ +++L+ ++ + + EEA +Q
Sbjct: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
Query: 1897 LAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
A+ ++L E+EE + + ++++ ++ R+K E + EE
Sbjct: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 595 bits (1534), Expect = e-169
Identities = 443/1444 (30%), Positives = 717/1444 (49%), Gaps = 117/1444 (8%)
Query: 38 VFVVDPKESYVKAIVQS--REGGKVTAKTEAGATVTVKEDQVFSMNPPKYDKIE------ 89
V++ DP+E + A + R G KV T + +S+NP +
Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGT-----ELDYSVNPESLPPLRNPDILV 67
Query: 90 ---DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRG 145
D+ +++LHEPAVL+NL+ R+A + +IYTYSG+ V +NPYK LP+Y ++ AY G
Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127
Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
+ + PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFAT++ +G
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187
Query: 206 KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASAD 265
+ED+++++NP+ EA GNAKT RNDNSSRFGK+ I F ++ A+
Sbjct: 188 AH-----------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGAN 236
Query: 266 IETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIEMLLITTNPYDFAFVSQGEITVP 324
+ TYLLEKSRV FQ + ER+YHIFYQ+ ++ ++ E + L + +++ + G +
Sbjct: 237 MSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIE 295
Query: 325 SIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA 384
++D+ E++ T +LGF D ++ ++K+ A++H GN++ E + +
Sbjct: 296 GVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHL 355
Query: 385 DKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVT 444
L L S + + LC ++ +E V K T Q NA ALAK IY +F ++V
Sbjct: 356 KVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVE 415
Query: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
RINQ L + FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY
Sbjct: 416 RINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475
Query: 505 KKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSN 564
KE I W IDF D I+LIE MGI +L+EEC+ P TD ++ KLY + ++
Sbjct: 476 MKEDIPWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNP 534
Query: 565 NFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLF 624
F+KP+ + F + H+A V+Y G+L+KN+D + + +V + + S A F
Sbjct: 535 LFEKPRMS----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFF 590
Query: 625 SGAQTAEAEGG------GGKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCI 677
T + G K+ K F+ TV + FR +L LM L +T PH+VRCI
Sbjct: 591 QENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCI 650
Query: 678 IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEG 737
PN+ K P + + ++ QLR GVLE IRI + +PSR Y +F RY +L E
Sbjct: 651 KPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QEL 708
Query: 738 QFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797
F D K+ + +L + D QY+FG TK+FF+AG + LE++R +KL Q Q R
Sbjct: 709 SFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMR 768
Query: 798 GFLMRVEFRKMMERRESIFCIQY---------NIRAFMNVKHWPWMKLYFKIKP-LLKSA 847
G+L R +F + ERR ++ QY I A + W + + + L++S
Sbjct: 769 GWLQRKKF--LRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSL 826
Query: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEE 907
MA + T + ++ R+ + +++E + LQ A A LA
Sbjct: 827 YQLIRMATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARA-WLARRRF 875
Query: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
+ + IQL +++ + ++ ED+ + N L K L + + I LE L K
Sbjct: 876 QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEK 935
Query: 968 VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKA 1027
+ E K K + ++E +AKL K L+ +Q LQ + +++
Sbjct: 936 AATHRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------ 986
Query: 1028 KTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKK 1087
K K++ L +++E ER + LE +L T D E Q L E++K
Sbjct: 987 KEKMDNLTKQLFDDVQKE-------ERQRMLLEKSFEL---KTQDYEKQIQSLKEEIKAL 1036
Query: 1088 EFEMSNLQGKIEDEQALAIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QR 1140
+ E LQ +E E + L+ ++ L + I E E+EIE +A + EK Q+
Sbjct: 1037 KDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQK 1096
Query: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
++ ++ EI+++L E S IE + R + DLE E A K
Sbjct: 1097 REMREKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKK 1146
Query: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
A V E Q K EKE L ++ L+ + + K + ++ ++
Sbjct: 1147 ATRVLE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEV 1201
Query: 1261 SEIKTKE---EEQQRLINELSAQKARLHTESGEFSRQLDEK-DAMVSQLSRGKQAFTQQI 1316
+ + ++ + ++ I+EL QK L E + ++ K + + +QL R ++ Q
Sbjct: 1202 TRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQR 1261
Query: 1317 EELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWR 1376
+ L+ Q E TK K L +Q + D L++Q+E E E K ++ S+ E
Sbjct: 1262 KALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD-- 1319
Query: 1377 TKYETDAIQRT-EELEEAKKKLAQRLQDAEEHVEAVNSK--CASLEKTKQRLQNEVEDLM 1433
+ E D R ++L++ K L++ + A + + K L+ ++ +++L+
Sbjct: 1320 LEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLI 1379
Query: 1434 IDVE 1437
+D++
Sbjct: 1380 LDLK 1383
Score = 81.6 bits (200), Expect = 7e-15
Identities = 107/533 (20%), Positives = 234/533 (43%), Gaps = 61/533 (11%)
Query: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEV 1372
T +++ L+++LE++ K L L S L E+ Q+ +AEL++
Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
Query: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCAS-LEKTKQRLQNEVED 1431
A R YE + + +EE KL + + E E + K E+ K+++ N +
Sbjct: 937 ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
Query: 1432 LMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNA 1491
L DV++ + L+K ++ K ++ + ++++ ++E ++L E ++++
Sbjct: 997 LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
Query: 1492 YEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEA 1551
E +H+ + L+ E++ L++Q+ K I E EK + L +K +++ ++
Sbjct: 1047 VEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1552 EASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ----------LKRNHLRVVES- 1600
+ + + +I + LE ++ R E E L++ LK+ RV+ES
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKA-TRVLESH 1154
Query: 1601 MQSTLDA---EIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDT 1657
QS D EI + N + + L ++ + N N + L + ++ D
Sbjct: 1155 FQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDF 1214
Query: 1658 QLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERV 1717
+ + + + + DL+ +L +A M+ ++EEL L R++ + +++ L+A +
Sbjct: 1215 KQQISELEKQKQDLEIRL---NEQAEKMKGKLEELSNQLHRSQE-EEGTQRKALEAQNEI 1270
Query: 1718 QLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQ 1777
HT+ K+KL I ++Q + + ++ E +A+ + E + +
Sbjct: 1271 ---HTKE------KEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLE 1321
Query: 1778 DTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEV 1830
+ +R+ K ++ VK L + +A + G K+ + RE E+++
Sbjct: 1322 EELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
Score = 42.0 bits (97), Expect = 0.006
Identities = 53/257 (20%), Positives = 113/257 (43%), Gaps = 26/257 (10%)
Query: 1668 QDDLKEQLAMVERRANLMQA------EVEELRASLERTERGRKMAEQELLDASERVQLLH 1721
+D KE +VE+ +L ++++L A LE+ R+ E++ + V+
Sbjct: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVE--- 955
Query: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
+ L +LET QIQ ++++ +E + + K + D +++KE+
Sbjct: 956 EKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD------DVQKEERQRM 1009
Query: 1782 HLERMKKNMEQTVKDLQLRLDEAEQ--LALKGGKKQIQKLEARVRELESEVESEQKHNVE 1839
LE K+ E +D + ++ ++ ALK K Q+Q L +++E +
Sbjct: 1010 LLE---KSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSK 1066
Query: 1840 AVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAK 1899
VK + + E+ ++ L Q + K++ Q +++ K+ +Q E+ + +V +
Sbjct: 1067 QVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLESYDIEDV---R 1120
Query: 1900 FRKLQHELEEAKERADI 1916
R +LE E ++
Sbjct: 1121 SRLSVEDLEHLNEDGEL 1137
Score = 37.0 bits (84), Expect = 0.19
Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 1818 KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877
+L RV+ L+ ++E + K N V+ ++ L D + I +L+ ++K T
Sbjct: 886 QLTYRVQRLQKKLEDQNKENHGLVE-------KLTSLAALRAGDVEKIQKLEAELEKAAT 938
Query: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKV 1935
+ Y+ + + + LAK +K ELE KE+ + KL+ K+ E+ K+
Sbjct: 939 HRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQL------KLQEKTEELKEKM 990
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 590 bits (1521), Expect = e-168
Identities = 434/1463 (29%), Positives = 718/1463 (49%), Gaps = 186/1463 (12%)
Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKR 148
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
Query: 209 EPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 268
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
Query: 269 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG-EITVPSID 327
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N +F + QG + +D
Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
Query: 328 DQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 388 AYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRIN 447
L ++ ++ LC+ ++ E K + Q NA ALAK IY K+F W+V +N
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 508 GIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 568 KPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA 627
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
Query: 628 QTAEAEGGGGKKG----------------GKKKGSSFQTVSALFRENLNKLMTNLRSTHP 671
+ A + G G+ +TV FR +L+ LM L +T P
Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655
Query: 672 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 731
H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715
Query: 732 SAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITR 791
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL R
Sbjct: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772
Query: 792 TQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEK 851
Q RG+L+R +K + R++ +Q +R + + Y K K+A +
Sbjct: 773 IQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATIIQ 822
Query: 852 EMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE----------- 887
+ M + K A T RK L E ++Q+
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHY 882
Query: 888 KNDL-----------QLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 937 NAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDET 992
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKD 998
Query: 993 IAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDL 1052
+ + EKK ++E + +Q+ + L +L++E L L
Sbjct: 999 LEQTRSEKKCIEE---------------------HADRYKQETEQLVSNLKEENTL---L 1034
Query: 1053 ERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKI 1112
++ K L + ++ Q++ TE +++L E+ K+ E +++ DE+ L +
Sbjct: 1035 KQEKEAL--NHRIVQQAKEMTETMEKKLVEETKQLELDLN-------DERLRYQNLLNEF 1085
Query: 1113 KELQARIEELEEEIEA-------------ERASRAKAEKQRSDLSRELEEISERLEEAGG 1159
L+ R ++L+EE+ S ++E S E+E+I R EE
Sbjct: 1086 SRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-S 1144
Query: 1160 ATSAQIEMN-----KKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSL 1214
++M+ +KR E ++ ++ +++ + E + K + G +++
Sbjct: 1145 EKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYE 1204
Query: 1215 QRVKQKLEKEKSELKMEINDL--ASNMETVSKAKANFEKMCRTLEDQLS----EIKTKEE 1268
+Q+LE E +LK E+N+L A + ++ + A R L +QL+ E+ ++E
Sbjct: 1205 SLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKE 1264
Query: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328
E L ++L +QK + + D+K+ M T +E++++ ++
Sbjct: 1265 EVLILRSQLVSQKEAIQPK--------DDKNTMTDS--------TILLEDVQKMKDKGEI 1308
Query: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKAN----SEVAQWRTKYETDAI 1384
A++ + L+ L + E+ E + G+ +AN S++ + +E +A
Sbjct: 1309 AQAYI--GLKETNRSSALDYHELNEDGELWL-VYEGLKQANRLLESQLQSQKRSHENEAE 1365
Query: 1385 QRTEELEEAKKK-------LAQRLQ-DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDV 1436
E++ K++ LAQ LQ E +E ASL+ RL NE DLM +
Sbjct: 1366 ALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQL 1419
Query: 1437 ERSNAACIALDKKQRNFDKVLAE 1459
E+ + L K+ + F K + E
Sbjct: 1420 EKQDKTVRKLKKQLKVFAKKIGE 1442
Score = 98.2 bits (243), Expect = 7e-20
Identities = 159/697 (22%), Positives = 290/697 (41%), Gaps = 87/697 (12%)
Query: 793 QAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKE 852
Q+ RGFL R +RK++ +++ IQ +R ++ H Y + + +
Sbjct: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTH------YKRSMHAIIYLQCCFR 897
Query: 853 MANMKEEFEKTKEELAKTEAKRK---ELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
K E +K K E E +K +E K++ L ++ ++ + + L + E
Sbjct: 898 RMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIY 957
Query: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
+ + K++ ER + EE T + L++E ++L+KD++ +E
Sbjct: 958 NSETE-------KLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
Query: 970 KE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAHQQTLD 1012
+ K TE V NL EE L + L T EKK ++E Q L
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLEL- 1069
Query: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072
DL E + L ++LE++ DD L++E L + + + K + ES
Sbjct: 1070 DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAER-- 1130
++ ++ E + + E S + K+ + +L ++LQK++ EL+ + +++E++ +
Sbjct: 1126 FSSEIAEM-EDIPSRTEEPS--EKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQ 1182
Query: 1131 --ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQ 1188
S+AK E++ ELE S + +E NKK + E ++R+ L E +
Sbjct: 1183 VLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALSEKSAP 1235
Query: 1189 HEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVS-KAKA 1247
E TA A + L EQ+ S V ++L+ K E+ + + L S E + K
Sbjct: 1236 -EVTAPG-----APAYRVLMEQLTS---VSEELDVRKEEVLILRSQLVSQKEAIQPKDDK 1286
Query: 1248 NFEKMCRTLEDQLSEIKTKEEEQQRLI-----NELSAQKARLHTESGE----FSRQLDEK 1298
N L + + ++K K E Q I N SA E GE +
Sbjct: 1287 NTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQAN 1346
Query: 1299 DAMVSQLSRGKQAFTQQIEELKRQL----EEETKAKSTLAHALQ---SARHDCDLLREQY 1351
+ SQL K++ + E L+ ++ EE + + LA LQ AR + L E
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEIT 1406
Query: 1352 EEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
E +L + K + V + + + + A ++ ELE + + Q +E + V
Sbjct: 1407 RLTNE-NLDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDEPIRPV 1464
Query: 1412 N------SKCASLEKTKQRLQNEVEDLMIDVERSNAA 1442
N LE K+ Q V++L+++++ A
Sbjct: 1465 NIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVA 1501
Score = 82.4 bits (202), Expect = 4e-15
Identities = 165/743 (22%), Positives = 298/743 (40%), Gaps = 172/743 (23%)
Query: 1084 LKKKEFEMSNLQGK-IEDEQALAIQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
+ K+E + ++ + +E + L I ++ KI +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAA 1194
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE++ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1195 ALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCR 1254
++HAD + EQ+ S + + L K++ E A N V +AK +M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE--------ALNHRIVQQAK----EMTE 1054
Query: 1255 TLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQ 1314
T+E +L E E ++L +L+ ++ R EFSR
Sbjct: 1055 TMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSR--------------------- 1087
Query: 1315 QIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQ 1374
+EE L+EE + + H + D E E +SE+A+
Sbjct: 1088 -LEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIF-----------SSEIAE 1132
Query: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMI 1434
D RTEE E K L L + + LE+ KQ +Q+E
Sbjct: 1133 ME-----DIPSRTEEPSEKKVPLDMSL------FLKLQKRVTELEQEKQVMQDE------ 1175
Query: 1435 DVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494
LD+K+ + A+ +++ + AELE + + L +E K+KN
Sbjct: 1176 -----------LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN---- 1220
Query: 1495 SLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEAS 1554
E+++L + ++E K E+ E TS+ E E
Sbjct: 1221 -----------------ELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLTSVSE-ELD 1260
Query: 1555 LEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRND 1614
+ EE ILR QL + +K A + ++ + ++E +Q
Sbjct: 1261 VRKEEVLILRSQL--------VSQKEAIQPKDDKNTMTDSTILLEDVQ------------ 1300
Query: 1615 ALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIR-GQDDLKE 1673
K K +G++ + I L NR +A L N G L L A R + L+
Sbjct: 1301 ----KMKDKGEIAQAYIGLKETNRSSALDYHEL-NEDGELWLVYEGLKQANRLLESQLQS 1355
Query: 1674 QLAMVERRANLMQAEVEELRASLERTERGRKMAEQEL-------LDAS--ERVQLLHTQN 1724
Q E A ++ E++ L+ E R +++ Q L ++AS + L +N
Sbjct: 1356 QKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN 1412
Query: 1725 TSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL------KKEQD 1778
L+ +K + + +++ +++ ++ E + I+ ++ E + +KE+D
Sbjct: 1413 LDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKD 1472
Query: 1779 TSAHLERMKKNMEQTVKDLQLRL 1801
LE K++ ++ VK+L L L
Sbjct: 1473 FQGMLEYKKEDEQKLVKNLILEL 1495
Score = 68.9 bits (167), Expect = 4e-11
Identities = 108/616 (17%), Positives = 257/616 (41%), Gaps = 74/616 (12%)
Query: 1346 LLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEEL----EEAKKKLAQRL 1401
L R Y+ A LQ + ++ + K E +++R ++L E +L +++
Sbjct: 877 LARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKV 936
Query: 1402 QDAEEHVEAVNSKCASLE----KTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVL 1457
+ + + + K +LE ++L++++E L + E + A + Q K+
Sbjct: 937 DEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKL- 995
Query: 1458 AEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLT 1517
+ +LE ++ E + + + K E+ + +L K EN L+QE L
Sbjct: 996 ----------RKDLEQTRSEKKCIEEHADRYKQETEQLVSNL---KEENTLLKQEKEALN 1042
Query: 1518 EQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEID 1577
+I + K + E ++K+L E +L+ L + ++ + R++ + +K E+
Sbjct: 1043 HRIVQQAKEM--TETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT 1100
Query: 1578 RKI------------AEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDA-----LRIKK 1620
+ E + + + + +E + S + + L+++K
Sbjct: 1101 LMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK 1160
Query: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
++ E ++ + +R+ + LR+ ++ + + A + LK Q +E
Sbjct: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAK-----EEERPQIRGAELEYESLKRQ--ELES 1213
Query: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
++ E+ ELR +L K A + + ++L Q TS+ + ++
Sbjct: 1214 ENKKLKNELNELRKALSE-----KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
Query: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTVKDL 1797
++ ++ + Q+ + K +TD+ ++ E+++K +D + +K+ + D
Sbjct: 1269 LRSQL--VSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDY 1326
Query: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
++ E + G KQ +L LES+++S+++ + + LR + +KE
Sbjct: 1327 HELNEDGELWLVYEGLKQANRL------LESQLQSQKRSHENEAEALRGEIQSLKE---- 1376
Query: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE---LEEAKERA 1914
E +R+ L Q+L + +++A + E +N NL +L+ + + + K++
Sbjct: 1377 -ENNRQQQLLAQNLQLPPEARIEASLQ--HEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433
Query: 1915 DIAESQVNKLRVKSRE 1930
+ ++ +L V E
Sbjct: 1434 KVFAKKIGELEVGQME 1449
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 590 bits (1520), Expect = e-168
Identities = 436/1455 (29%), Positives = 711/1455 (48%), Gaps = 197/1455 (13%)
Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKR 148
D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ +
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188
Query: 209 EPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 268
+ +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T
Sbjct: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241
Query: 269 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG-EITVPSID 327
YLLEKSRV FQ + ER+YHIFYQ+ ++ K +ML + N +F + QG + +D
Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300
Query: 328 DQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360
Query: 388 AYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRIN 447
L ++ ++ LC+ ++ E K + Q NA ALAK IY K+F W+V +N
Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420
Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 508 GIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567
I W IDF D CI LIE +GI +L+EEC PK TD ++ KLY HL K F+
Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 568 KPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA 627
KP+ + F + H+A V+Y G+L+KNKD + E + + + S K L LF
Sbjct: 540 KPRLS----NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595
Query: 628 QTAEAEGGGGKKG----------------GKKKGSSFQTVSALFRENLNKLMTNLRSTHP 671
+ A + G G+ +TV FR +L+ LM L +T P
Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655
Query: 672 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 731
H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL
Sbjct: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715
Query: 732 SAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITR 791
+ D K+ + +L + +D +Y+FG TK+FF+AG + LE++R +KL R
Sbjct: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772
Query: 792 TQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEK 851
Q RG+L+R +K + R++ +Q +R + + Y K K+A +
Sbjct: 773 IQKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQ-------ARCYAKFLRRTKAATIIQ 822
Query: 852 EMANMKEEFEKTKEELAKT-------------EAKRKELEEKMVTLMQE----------- 887
+ M + K A T RK L E ++Q+
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHY 882
Query: 888 KNDL-----------QLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936
K + ++ + E L ++ K I +E KI ++ + +++ +
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 937 NAELTAKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDET 992
L K LE E +L+ D++ L+L+ E+E +V +L EE+A L +
Sbjct: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKD 998
Query: 993 IAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDL 1052
+ + EKK ++E + +Q+ + L +L++E L L
Sbjct: 999 LEQTRSEKKCIEE---------------------HADRYKQETEQLVSNLKEENTL---L 1034
Query: 1053 ERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKI 1112
++ K L + ++ Q++ TE +++L E+ K+ E +++ DE+ L +
Sbjct: 1035 KQEKEAL--NHRIVQQAKEMTETMEKKLVEETKQLELDLN-------DERLRYQNLLNEF 1085
Query: 1113 KELQARIEELEEEIEA-------------ERASRAKAEKQRSDLSRELEEISERLEEAGG 1159
L+ R ++L+EE+ S ++E S E+E+I R EE
Sbjct: 1086 SRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP-S 1144
Query: 1160 ATSAQIEMN-----KKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSL 1214
++M+ +KR E ++ ++ +++ + E + K + G +++
Sbjct: 1145 EKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYE 1204
Query: 1215 QRVKQKLEKEKSELKMEINDL--ASNMETVSKAKANFEKMCRTLEDQLS----EIKTKEE 1268
+Q+LE E +LK E+N+L A + ++ + A R L +QL+ E+ ++E
Sbjct: 1205 SLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKE 1264
Query: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328
E L ++L +QK + + D+K+ M T +E++++ K
Sbjct: 1265 EVLILRSQLVSQKEAIQPK--------DDKNTMTDS--------TILLEDVQKM-----K 1303
Query: 1329 AKSTLAHALQSARHDCDLLREQYEEEQ---EAKAELQRGMSKANSEVAQWRTKYETDAIQ 1385
K +A A + LL Q + ++ E +AE RG E +++
Sbjct: 1304 DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRG---------------EIQSLK 1348
Query: 1386 RTEELEEAKKKLAQRLQ-DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACI 1444
EE ++ LAQ LQ E +E ASL+ RL NE DLM +E+ +
Sbjct: 1349 --EENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVR 1400
Query: 1445 ALDKKQRNFDKVLAE 1459
L K+ + F K + E
Sbjct: 1401 KLKKQLKVFAKKIGE 1415
Score = 84.0 bits (206), Expect = 1e-15
Identities = 117/548 (21%), Positives = 239/548 (43%), Gaps = 85/548 (15%)
Query: 1084 LKKKEFEMSNLQGK-IEDEQALAIQLQKKIKELQARIEE--------LEEEIEAERASRA 1134
+ K+E + ++ + +E + L I ++ KI +LQ +++E +E+ E +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAA 1194
+ EK RSDL R ++SE EEA AT + + + E K+R+DLE++ + +
Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009
Query: 1195 ALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCR 1254
++HAD + EQ+ S + + L K++ E A N V +AK +M
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE--------ALNHRIVQQAK----EMTE 1054
Query: 1255 TLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQ 1314
T+E +L E E ++L +L+ ++ R EFSR + D + +++
Sbjct: 1055 TMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LMV 1103
Query: 1315 QIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGM----SKANS 1370
+ + + + T + + + S + + + + EE E K L + K +
Sbjct: 1104 HVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVT 1163
Query: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
E+ Q + + + ++ E++ +K K +R Q +E + K LE ++L+NE+
Sbjct: 1164 ELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELN 1223
Query: 1431 DLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKN 1490
+L + +A + +VL E E EL+ ++E L ++L K
Sbjct: 1224 ELRKALSEKSAPEVTAPGAPAY--RVLMEQLTSVSE---ELDVRKEEVLILRSQLVSQKE 1278
Query: 1491 AYEES------------LDHLETLKRENKNLQ-----QEISDLTEQIAEGGKHIHE---- 1529
A + L+ ++ +K + + Q +E + L E + K HE
Sbjct: 1279 AIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAE 1338
Query: 1530 -----LEKVKKQLDHEKSELQTSLE-----EAEASLEHEEGKILRIQLELNQVKSEIDRK 1579
++ +K++ + ++ L +L+ EASL+HE ++ L+L + + D+
Sbjct: 1339 ALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKT 1398
Query: 1580 IAEKDEEL 1587
+ + ++L
Sbjct: 1399 VRKLKKQL 1406
Score = 80.5 bits (197), Expect = 1e-14
Identities = 105/498 (21%), Positives = 205/498 (41%), Gaps = 43/498 (8%)
Query: 806 RKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEK----EMANMKEEFE 861
RK+ E+ + C+ + + + KL ++ L S E K + +++EE
Sbjct: 934 RKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIA 993
Query: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 921
K +++L +T +++K +EE QE L ++ E L +E + I +Q
Sbjct: 994 KLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI---VQQAK 1050
Query: 922 KIKEVTERAEDEEEINAELTAKKRKLE-----DECSELKKDIDDL--ELTL-AKVEKEKH 973
++ E E+ EE EL +L +E S L++ DDL E+TL V K H
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGH 1110
Query: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033
+ + E IA++ +E ++ + ++ L K T+LEQ
Sbjct: 1111 KRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEK---KVPLDMSLFLKLQKRVTELEQ 1167
Query: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSN 1093
+ ++ L+++++ + R+K K E ++ +Q+L + KK + E++
Sbjct: 1168 EKQVMQDELDRKEEQVL---RSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
Query: 1094 LQGKIEDEQA-------------LAIQLQKKIKELQARIEEL----EEEIEAERASRAKA 1136
L+ + ++ A L QL +EL R EE+ + + + A + K
Sbjct: 1225 LRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKD 1284
Query: 1137 EKQRSDLSRELEEISERLEEAGGATSAQI---EMNKKREAEFQKMRR--DLEESTLQHEA 1191
+K S L E +++++ G A I E N+ E++ Q +R + E L+ E
Sbjct: 1285 DKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEI 1344
Query: 1192 TAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEK 1251
+ + Q+ R++ L+ E + L E DL +E K +K
Sbjct: 1345 QSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKK 1404
Query: 1252 MCRTLEDQLSEIKTKEEE 1269
+ ++ E++ + E
Sbjct: 1405 QLKVFAKKIGELEVGQME 1422
Score = 60.8 bits (146), Expect = 1e-08
Identities = 97/472 (20%), Positives = 205/472 (43%), Gaps = 87/472 (18%)
Query: 1499 LETLKRENKNLQQEISDLTEQIAEGGKH----IHELEKVKKQLDHEKSELQTSLEEAEAS 1554
+E K+ + ++ +I L ++ E K + +L ++ + E +L++ LE + S
Sbjct: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS 974
Query: 1555 LEHEE---GKILRIQLELNQVKSEIDRKIAEK---DEELDQLKRNHLRVVESMQSTLDAE 1608
E + G++L +Q E+ +++ ++++ +EK +E D+ K+ ++V ++
Sbjct: 975 EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL------- 1027
Query: 1609 IRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLD---DAI 1665
+ N L+ +K+ LNH Q A+ + + + + QL LD + +
Sbjct: 1028 -KEENTLLKQEKEA----------LNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERL 1076
Query: 1666 RGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNT 1725
R Q+ L E + ER +L EE+ + + G K R H+ N
Sbjct: 1077 RYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPGHK-----------RTDSTHSSNE 1121
Query: 1726 SLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
S E S EMEDI +R E KK D ++ + L++
Sbjct: 1122 S--------EYIFSSEIAEMEDI--PSRTEEPSEKKVPLDMSLFLK-----------LQK 1160
Query: 1786 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE------SEVESEQKHNVE 1839
+EQ + +Q LD E+ L+ K+ ++ + R ELE E+ESE K
Sbjct: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220
Query: 1840 AVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVDKLQTKVK---------AYKRQAE 1887
+ LRK E+ E+T + ++ +L + ++L + + +++A
Sbjct: 1221 ELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI 1280
Query: 1888 EAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVISEE 1939
+ ++ N + L ++++ K++ +IA++ + L+ +R + +++ S++
Sbjct: 1281 QPKDDKN-TMTDSTILLEDVQKMKDKGEIAQAYIG-LKETNRLLESQLQSQK 1330
Score = 60.1 bits (144), Expect = 2e-08
Identities = 97/528 (18%), Positives = 224/528 (42%), Gaps = 73/528 (13%)
Query: 1453 FDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEES-------LDHLETLKRE 1505
+ K+ + K + Q +++ K+ + L +L ++ Y L+ L+ + E
Sbjct: 918 YKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE 977
Query: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
K + L E+IA+ K + + KK ++ + E+ ++L+ EE +L+
Sbjct: 978 AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLK-EENTLLK- 1035
Query: 1566 QLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDA-EIRSR-----NDALRIK 1619
Q K ++ +I ++ +E+ + L V E+ Q LD + R R N+ R++
Sbjct: 1036 -----QEKEALNHRIVQQAKEMTETMEKKL-VEETKQLELDLNDERLRYQNLLNEFSRLE 1089
Query: 1620 KKMEGDLNEMEIQLN--HANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQ--- 1674
++ + EM + ++ + ++ + ++ I ++D ++ E+
Sbjct: 1090 ERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVP 1149
Query: 1675 -----LAMVERRANLMQAEVEELRASLERTERG--RKMAEQELLDASERVQLLHTQNTSL 1727
+++R ++ E + ++ L+R E R A++E ER Q+ +
Sbjct: 1150 LDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEE-----ERPQIRGAELEYE 1204
Query: 1728 INTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER-- 1785
+++LE++ +++ E+ ++ + EK+ +T A + EQ TS E
Sbjct: 1205 SLKRQELESENKKLKNELNEL---RKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDV 1261
Query: 1786 -------------------MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ-KLEARVRE 1825
K+ + T+ D + L++ +++ KG Q L+ R
Sbjct: 1262 RKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRL 1321
Query: 1826 LESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885
LES+++S+++ + + LR + +KE E +R+ L Q+L + +++A +
Sbjct: 1322 LESQLQSQKRSHENEAEALRGEIQSLKE-----ENNRQQQLLAQNLQLPPEARIEASLQ- 1375
Query: 1886 AEEAEEQSNVNLAKFRKLQHE---LEEAKERADIAESQVNKLRVKSRE 1930
E +N NL +L+ + + + K++ + ++ +L V E
Sbjct: 1376 -HEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQME 1422
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 569 bits (1466), Expect = e-161
Identities = 457/1595 (28%), Positives = 777/1595 (48%), Gaps = 167/1595 (10%)
Query: 36 TSVFVVDPKESYVKAIVQS--REGGK-----VTAKTEAGATVTVKEDQV-FSMNPPKYDK 87
T V++ DP E + A + +EG K + +T + V+ +Q+ F NP
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
Query: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGK 146
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
Query: 207 KEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADI 266
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
Query: 267 ETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIEMLLITTNPYDFAFVSQG-EITVP 324
TYLLEKSRV FQ ER+YHIFYQ+ + PE E+ L T+ DF + SQG + ++
Sbjct: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
Query: 325 SIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE-- 382
+DD E+ T A +LG +++I+K+ +++H G++ QAE DG
Sbjct: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
Query: 383 VADKAAYLTS------LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYE 436
++ + YL++ + + + LC+ ++ +E K ++QQV NA ALAK IY
Sbjct: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
Query: 437 KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
Query: 497 FVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
F LEQEEY KE I W IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
Query: 557 EQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSA 616
++H S +FQKP+ + F +VH+A V+Y G+L+KN+D + E + + + S
Sbjct: 530 DRH-SSSQHFQKPRMS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
Query: 617 MKTLAFLFSGAQTAEAEGGGGKKGGKK-------------KGSSFQTVSALFRENLNKLM 663
+A LF + GK K +TV FR +L+ LM
Sbjct: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
Query: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
Query: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDE 783
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R +
Sbjct: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
Query: 784 KLAQLITRTQAICRGFLMRVEFRKMMERRESI--FCIQYNIRA----FMNVKHWPWMKLY 837
K Q RG+L +V++ ++ ++ +C + R ++ ++ +
Sbjct: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
Query: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
++++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 823 YRMQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARR 878
Query: 898 EADALADAE---ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
L DA + +++K + +L+A ++ AE + +N + K +RK++++
Sbjct: 879 HFQRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ 937
Query: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1010
E K + L +T + E + ++ + + ++T +L +E ++L+ Q+
Sbjct: 938 NKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG--EDTSLRLQEEVESLRTELQRA 995
Query: 1011 LDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQEST 1070
+ ++ ED ++ K +L ++V D LEQE L D K +L + L Q
Sbjct: 996 HSERKILED---AHSREKDELRKRVAD----LEQENALLKD---EKEQLNNQI-LCQSKD 1044
Query: 1071 MDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEE--IEA 1128
+N + E L KKE +E+E++ L K+ +L+ R + L +E I
Sbjct: 1045 EFAQN---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK 1092
Query: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQ 1188
+ + +S L + S E G A + +EE L+
Sbjct: 1093 QTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------------LQQVEEIGLE 1137
Query: 1189 HEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKAN 1248
A + K V EL ++ LQ +K E++ S+ K++ ++++ A
Sbjct: 1138 KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDIDLDPNADLA 1196
Query: 1249 FEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRG 1308
+ + R E++++ ++ + +NEL A T++ D +++QL
Sbjct: 1197 YNSLKR------QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLA 1250
Query: 1309 KQAFTQQIEE---LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGM 1365
+ + EE L+ Q+ + + +A + + +QE E G+
Sbjct: 1251 HEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGV 1310
Query: 1366 SKANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-DAEEHVEAVNSKCASLEKTKQ 1423
+ NS+ W E + + L++ + L +LQ + EH E V A LE K+
Sbjct: 1311 CQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKE 1370
Query: 1424 RLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLST 1483
+DK+Q+ F + L E Q E Q+ SR L+
Sbjct: 1371 E---------------------MDKQQQTFCQTLL----LSPEAQVEFGVQQEISR-LTN 1404
Query: 1484 ELFKVKNAYEESLDHLETLKRENKNLQQEISDL--TEQIAEGGKHIHELEKVKKQLDHEK 1541
E +K E+ + LK++ K ++ DL + +A+ + HEL + + + ++
Sbjct: 1405 ENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVTVQRKE 1463
Query: 1542 SELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
+ Q LE H+E + L I+ + +K ++
Sbjct: 1464 KDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
Score = 62.8 bits (151), Expect = 3e-09
Identities = 126/669 (18%), Positives = 265/669 (39%), Gaps = 84/669 (12%)
Query: 1178 MRRDLEESTLQHEATAAA------LRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKME 1231
+RR + ++H+AT + ++H + + I R+ K +E L++E
Sbjct: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
Query: 1232 INDLASNMETVSKAKAN-FEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGE 1290
A +++ ++ N ++ R +++Q E KT E+ + + + RL E
Sbjct: 910 ARS-AEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVH 968
Query: 1291 FSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350
+ + E ++ Q +++E L+ +L+ + L A + D LR++
Sbjct: 969 YQQSPGEDTSLRLQ---------EEVESLRTELQRAHSERKILEDAHSREK---DELRKR 1016
Query: 1351 YEEEQEAKAELQRGMSKANSEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQRLQD 1403
+ ++ A L+ + N+++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQ 1076
Query: 1404 AEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQK 1463
E+ + + + +++T +N ++ + SN I+ + D + Q+
Sbjct: 1077 LEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESD-SNYPSISTSEIGDTEDAL-----QQ 1130
Query: 1464 YEETQAELEAS--------QKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEIS- 1514
EE E A QK R L E K++ E+ + ++ K + + Q +I
Sbjct: 1131 VEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDL 1189
Query: 1515 DLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKS 1574
D +A ELE K+L ++ +EL+ ++ + G L LNQ+K
Sbjct: 1190 DPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL 1249
Query: 1575 EIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLN 1634
EEL+ K L + + S + RN I + +E +
Sbjct: 1250 --------AHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD-- 1299
Query: 1635 HANRQAAEALRNLRNTQGILKDTQLHLDDAIRG--QDDLKEQLAMVERRANLM----QAE 1688
A EA + T +D +D G LK+ ++E + + E
Sbjct: 1300 --QEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357
Query: 1689 VEELRASLERTERGRKMAEQEL-------------LDASERVQLLHTQNTSLINTKKKLE 1735
VE L+A LE + +Q + + L +N L +KLE
Sbjct: 1358 VEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
Query: 1736 TDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL-------KKEQDTSAHLERMKK 1788
+ +++ +++ +++A++ E A +A+ + EL +KE+D LE K+
Sbjct: 1418 KNERKLKKQLKIYMKKAQDLE--AAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
Query: 1789 NMEQTVKDL 1797
+ +++L
Sbjct: 1476 DEALLIRNL 1484
Score = 47.8 bits (112), Expect = 1e-04
Identities = 78/371 (21%), Positives = 149/371 (40%), Gaps = 57/371 (15%)
Query: 1605 LDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDA 1664
L E RS R+ ME + +++ +++ N++ L T T + +
Sbjct: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT------TSTYTMEV 959
Query: 1665 IRGQDDLKE-QLAMVERRANLMQAEVEELRASLERTERGRKMAE----QELLDASERVQL 1719
R + +L Q + E + +Q EVE LR L+R RK+ E +E + +RV
Sbjct: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
Query: 1720 LHTQNTSLINTKKKLETDI-----------SQIQGEMEDIVQEARNAEEKAKKAITDAAM 1768
L +N L + K++L I S + M+ ++E R+ + K +
Sbjct: 1020 LEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQ 1079
Query: 1769 MAEELKKEQDTSAHLERMKKNMEQT----------------VKDLQLRLDEAEQLALKGG 1812
+ L+ E ++N + D + L + E++ L+
Sbjct: 1080 RYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKA 1139
Query: 1813 KKQIQ---KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED-------R 1862
+ KL+ RVRELE E +K V+ K ++ ++V+ QT+ D
Sbjct: 1140 AMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLA 1196
Query: 1863 KNILRLQDLVD---KLQTKVKAYKRQAEEAEEQSNVNLA---KFRKLQHELEEAKERADI 1916
N L+ Q+L KL+ + ++ + Q+N + + L ++L+ A E ++
Sbjct: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256
Query: 1917 AESQVNKLRVK 1927
+ +V LR +
Sbjct: 1257 RKEEVLILRTQ 1267
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 501 bits (1290), Expect = e-141
Identities = 420/1673 (25%), Positives = 789/1673 (47%), Gaps = 192/1673 (11%)
Query: 58 GKVTAKTEA-GATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
GKV K + GA + V ED V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
Query: 117 TYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
Query: 177 ITGESGAGKTVNTKRVIQYFATIA-VTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGN 235
+ G SG+GKT + + ++QY ATIA ++G K ++ + LLEAFGN
Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFS-----------VEKWQALYTLLEAFGN 544
Query: 236 AKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS- 294
+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 545 SPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLAC 604
Query: 295 ---NKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVA 351
+ EL L N + +++ E + +L A A+ +LG + DE+ A
Sbjct: 605 GDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKA 661
Query: 352 IYKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLTSLNSADLLKSLCYPRVKVG 410
+ + A+ H G ++ E + E A KAAYL + +L ++ + K G
Sbjct: 662 CWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG 721
Query: 411 ----NEFVTKGQTVQQVYNAVG----------ALAKAIYEKMFLWMVTRINQQLDTKQPR 456
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 722 TLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHS 781
Query: 457 QYFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 782 LCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIE 841
Query: 511 WEFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKL 555
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L
Sbjct: 842 LAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERL 901
Query: 556 YEQHLGKSNN--FQKPKPAKGKPEAHFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVG 610
+ + + + Q P KP HF L H GT V+YN+ GWL+ K +P +
Sbjct: 902 FSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
Query: 611 LYQKSAMKTLAFLF---SGAQTAEAEGGGGKKGGKKKG--------SSFQTVSALFRE-- 657
L Q S K ++ LF +G+ T + G +GG + +F T A ++
Sbjct: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
Query: 658 -------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA--- 687
++ L+ ++ + HFV C +P +E P
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
Query: 688 ------MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ--- 738
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
Query: 739 -FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797
+D ++A E+LL ++++ + G ++VFF+AG L LEE RDE+ ++ +T QA CR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
Query: 798 GFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMK 857
G+L R F+K + +I C+Q NI+ VK WPW KL+ ++PL++ +E+++ N
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
Query: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKI 917
EE ++ + +L K E +R EL L ++L ++ E + A + D ++
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 918 QLEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEK 972
+ E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAV 1379
Query: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
+ K L +E ++ + + K+ L+ D + + + L K +L
Sbjct: 1380 REVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
Query: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
++ D + LE ++ +LE+ +R+ + +L A E + +++L + E
Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
Query: 1093 NLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
+L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++ E
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEE 1556
Query: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQID 1212
L+E G + + E E ++MR+ + + R+ + ++ Q++
Sbjct: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
Query: 1213 SLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQR 1272
KQK+ +EK EL+ ++ L+ + + +FE R +D L K + Q
Sbjct: 1617 EEYEDKQKVLREKRELEGKLATLSDQVN-----RRDFESEKRLRKD-LKRTKALLADAQL 1670
Query: 1273 LINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332
+++ L A E + QL+E + + + ++A +IE+L Q+++ KAK+
Sbjct: 1671 MLDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
Query: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1392
L L + + + ++ + EE+QE EL M K + VAQ
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------------ 1768
Query: 1393 AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452
A + LAQ + D + +E N + L++ Q LQ++VE L +Q
Sbjct: 1769 ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL----------------EQSM 1811
Query: 1453 FDKVLA---EWKQKYEETQAELEASQ-KESRSLSTELFKVKNAYEESLDHL----ETLKR 1504
DK L E K + ET+ E E +Q K SL++ L + E D K
Sbjct: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
Query: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564
+NK LQ+++ D E++ EL + + + +K EL+ LE EA+ + + +
Sbjct: 1872 QNKRLQRQLRDTKEEMG-------ELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1924
Query: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617
+ +++ I+ ++ E DE D + S +D+E+ R D ++
Sbjct: 1925 AFKRIGDLQAAIEDEM-ESDENEDLIN-------SEGDSDVDSELEDRVDGVK 1969
Score = 192 bits (487), Expect = 3e-48
Identities = 153/687 (22%), Positives = 333/687 (48%), Gaps = 47/687 (6%)
Query: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQL-DEKDA--MVSQLS 1306
E+ R ++++ ++++K E+ ++ NEL RL + E + +L DE++ SQL
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1307 RGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY----EEEQEAKAELQ 1362
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1363 RGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK 1422
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1423 QRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLS 1482
QRL E++D + +E L+KKQR FD L++ ++ + + + E Q+E L
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
Query: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKS 1542
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + L+ +
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQ 1602
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 1603 STLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR-NLRNTQGILKDTQLHL 1661
L+ E + LR K+++EG L + Q+N + ++ + LR +L+ T+ +L D QL L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 1662 DDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLH 1721
D ++ K ++A ++ ++EE + + RK E E+ D LH
Sbjct: 1673 DH-LKNSAPSKREIAQLKN-------QLEESEFTCAAAVKARKAMEVEIED-------LH 1717
Query: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Query: 1782 HLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAV 1841
+ + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+S+VE ++ V+
Sbjct: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
Query: 1842 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFR 1901
+ + E +++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
Query: 1902 KLQHELEEAKER-ADIAESQVNKLRVK 1927
+LQ +L + KE ++A + R K
Sbjct: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
Score = 74.7 bits (182), Expect = 8e-13
Identities = 64/302 (21%), Positives = 146/302 (48%), Gaps = 11/302 (3%)
Query: 1647 LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMA 1706
+RN ++ + L+ A + +++L+ +E R + + +E+ + R + E +
Sbjct: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAE 1315
Query: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIVQEARNAEEK 1758
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1316 TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLK 1374
Query: 1759 AKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1817
++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q
Sbjct: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQ 1433
Query: 1818 KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877
+L A +++ + +E +Q N E K R+ + + + + + ++ +LQ D L
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVIS 1937
+ + K+Q EE + K L+ EL++ + E+ + K++ + R++ KV
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 1938 EE 1939
+E
Sbjct: 1554 QE 1555
Score = 32.7 bits (73), Expect = 3.5
Identities = 57/280 (20%), Positives = 118/280 (42%), Gaps = 43/280 (15%)
Query: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET---DI 1738
A L+Q +V LR L RG + LLDA + + + +++ + +
Sbjct: 1082 AGLLQLDVPLLRTQL----RGSR-----LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHL 1132
Query: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM-EQTVKDL 1797
++ G +V E R EE + + + L + + L R+++ EQT ++L
Sbjct: 1133 TKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNL 1192
Query: 1798 QL--------------RLDEAEQLALKGGKKQIQK-----------LEARVREL-ESEVE 1831
L + + + LA++ +K I+K L VR L E ++
Sbjct: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
Query: 1832 SEQKHNV-EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAE 1890
EQ N E ++ LR ++++ + E R N RL+ + +L +++ + E A
Sbjct: 1253 EEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
Query: 1891 EQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
+ + A+ + + E++E + + D + Q+ + ++ E
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 501 bits (1289), Expect = e-141
Identities = 417/1674 (24%), Positives = 794/1674 (47%), Gaps = 179/1674 (10%)
Query: 58 GKVTAKTEA-GATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
GKV K + GA + V ED V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
Query: 117 TYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
Query: 177 ITGESGAGKTVNTKRVIQYFATIA-VTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGN 235
+ G SG+GKT + + ++QY ATIA ++G K ++ + LLEAFGN
Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFS-----------VEKWQALYTLLEAFGN 544
Query: 236 AKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS- 294
+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 545 SPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLAC 604
Query: 295 ---NKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVA 351
+ EL L N + +++ E + +L A A+ +LG + DE+ A
Sbjct: 605 GDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKA 661
Query: 352 IYKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLTSLNSADLLKSLCYPRVKVG 410
+ + A+ H G ++ E + E A KAAYL + +L ++ + K G
Sbjct: 662 CWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG 721
Query: 411 ----NEFVTKGQTVQQVYNAVG----------ALAKAIYEKMFLWMVTRINQQLDTKQPR 456
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 722 TLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHS 781
Query: 457 QYFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 782 LCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIE 841
Query: 511 WEFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKL 555
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L
Sbjct: 842 LAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERL 901
Query: 556 YEQHLGKSNN--FQKPKPAKGKPEAHFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVG 610
+ + + + Q P KP HF L H GT V+YN+ GWL+ K +P +
Sbjct: 902 FSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
Query: 611 LYQKSAMKTLAFLF---SGAQTAEAEGGGGKKGGKKKG--------SSFQTVSALFRE-- 657
L Q S K ++ LF +G+ T + G +GG + +F T A ++
Sbjct: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
Query: 658 -------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA--- 687
++ L+ ++ + HFV C +P +E P
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
Query: 688 ------MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ--- 738
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
Query: 739 -FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797
+D ++A E+LL ++++ + G ++VFF+AG L LEE RDE+ ++ +T QA CR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
Query: 798 GFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMK 857
G+L R F+K + +I C+Q NI+ VK WPW KL+ ++PL++ +E+++ N
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
Query: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKI 917
EE ++ + +L K E +R EL L ++L ++ E + A + D ++
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 918 QLEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEK 972
+ E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAV 1379
Query: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
+ K L +E ++ + + K+ L+ D + + + L K +L
Sbjct: 1380 REVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
Query: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
++ D + LE ++ +LE+ +R+ + +L A E + +++L + E
Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
Query: 1093 NLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
+L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++ E
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEE 1556
Query: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQID 1212
L+E G + + E E ++MR+ + + R+ + ++ Q++
Sbjct: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
Query: 1213 SLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQR 1272
KQK+ +EK EL+ ++ L+ + + +FE R +D L K + Q
Sbjct: 1617 EEYEDKQKVLREKRELEGKLATLSDQVN-----RRDFESEKRLRKD-LKRTKALLADAQL 1670
Query: 1273 LINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332
+++ L A E + QL+E + + + ++A +IE+L Q+++ KAK+
Sbjct: 1671 MLDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
Query: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1392
L L + + + ++ + EE+QE EL M K + VAQ
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------------ 1768
Query: 1393 AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452
A + LAQ + D + +E N + L++ Q LQ++VE L +Q
Sbjct: 1769 ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL----------------EQSM 1811
Query: 1453 FDKVLA---EWKQKYEETQAELEASQ-KESRSLSTELFKVKNAYEESLDHL----ETLKR 1504
DK L E K + ET+ E E +Q K SL++ L + E D K
Sbjct: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
Query: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564
+NK LQ+++ D E++ E + E + K +L+ + L+ + + +A L+ +I
Sbjct: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931
Query: 1565 IQLEL-NQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617
+Q + ++++S+ + + +++ + +E S +D+E+ R D ++
Sbjct: 1932 LQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEG-DSDVDSELEDRVDGVK 1984
Score = 192 bits (487), Expect = 3e-48
Identities = 153/687 (22%), Positives = 333/687 (48%), Gaps = 47/687 (6%)
Query: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQL-DEKDA--MVSQLS 1306
E+ R ++++ ++++K E+ ++ NEL RL + E + +L DE++ SQL
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1307 RGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY----EEEQEAKAELQ 1362
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1363 RGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK 1422
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1423 QRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLS 1482
QRL E++D + +E L+KKQR FD L++ ++ + + + E Q+E L
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
Query: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKS 1542
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + L+ +
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQ 1602
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 1603 STLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR-NLRNTQGILKDTQLHL 1661
L+ E + LR K+++EG L + Q+N + ++ + LR +L+ T+ +L D QL L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 1662 DDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLH 1721
D ++ K ++A ++ ++EE + + RK E E+ D LH
Sbjct: 1673 DH-LKNSAPSKREIAQLKN-------QLEESEFTCAAAVKARKAMEVEIED-------LH 1717
Query: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Query: 1782 HLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAV 1841
+ + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+S+VE ++ V+
Sbjct: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
Query: 1842 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFR 1901
+ + E +++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
Query: 1902 KLQHELEEAKER-ADIAESQVNKLRVK 1927
+LQ +L + KE ++A + R K
Sbjct: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
Score = 74.7 bits (182), Expect = 8e-13
Identities = 64/302 (21%), Positives = 146/302 (48%), Gaps = 11/302 (3%)
Query: 1647 LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMA 1706
+RN ++ + L+ A + +++L+ +E R + + +E+ + R + E +
Sbjct: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAE 1315
Query: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIVQEARNAEEK 1758
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1316 TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLK 1374
Query: 1759 AKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1817
++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q
Sbjct: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQ 1433
Query: 1818 KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877
+L A +++ + +E +Q N E K R+ + + + + + ++ +LQ D L
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVIS 1937
+ + K+Q EE + K L+ EL++ + E+ + K++ + R++ KV
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 1938 EE 1939
+E
Sbjct: 1554 QE 1555
Score = 32.7 bits (73), Expect = 3.5
Identities = 57/280 (20%), Positives = 118/280 (42%), Gaps = 43/280 (15%)
Query: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET---DI 1738
A L+Q +V LR L RG + LLDA + + + +++ + +
Sbjct: 1082 AGLLQLDVPLLRTQL----RGSR-----LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHL 1132
Query: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM-EQTVKDL 1797
++ G +V E R EE + + + L + + L R+++ EQT ++L
Sbjct: 1133 TKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNL 1192
Query: 1798 QL--------------RLDEAEQLALKGGKKQIQK-----------LEARVREL-ESEVE 1831
L + + + LA++ +K I+K L VR L E ++
Sbjct: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
Query: 1832 SEQKHNV-EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAE 1890
EQ N E ++ LR ++++ + E R N RL+ + +L +++ + E A
Sbjct: 1253 EEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
Query: 1891 EQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
+ + A+ + + E++E + + D + Q+ + ++ E
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 482 bits (1241), Expect = e-135
Identities = 311/949 (32%), Positives = 529/949 (55%), Gaps = 54/949 (5%)
Query: 52 VQSREGGKVTAKTEAGATVTVKED-----QVFSMNPPKYDKIEDMAMMTHLHEPAVLYNL 106
V S G V +T+ G T K+ +V +M+P + ++DMA +T LH +++YNL
Sbjct: 24 VNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNL 83
Query: 107 KERYAAWMIYTYSGLFCVTVNPYKWLP-VYNPEVVTAYRGKKRQEAPPHIFSISDNAYQF 165
+RY IYTY G +VNPY+ + +Y P + Y + E PPHIF+I++ Y+
Sbjct: 84 FQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRC 143
Query: 166 MLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIIS 225
+ +NQ ILI+GESGAGKT +TK ++++ + I+ ++ E + + +E I+
Sbjct: 144 LWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----QQSLELSLKEKTSCVERAILE 199
Query: 226 ANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERS 285
++P++EAFGNAKTV N+NSSRFGKF++++ G + I YLLEK+RV Q ER+
Sbjct: 200 SSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERN 259
Query: 286 YHIFYQILSNKKPELIEMLLITTNPYDFAFVSQ-GEITVPSIDDQEELMATDSAVDILGF 344
YHIFY +L+ + E E ++T P ++ +++Q G + +I DQE +A+D++ F
Sbjct: 260 YHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDKTISDQESFREVITAMDVMQF 318
Query: 345 TADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCY 404
+ +E + +L ++H GN++F A+ ++A L L+ L +L
Sbjct: 319 SKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQ 375
Query: 405 PRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLD 464
+ + E + VQQ ++ +LA A+Y F W++ +IN ++ + + IG+LD
Sbjct: 376 RSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFK-SIGILD 434
Query: 465 IAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACI 524
I GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY +EG+ WE ID+ +D C+
Sbjct: 435 IFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECL 493
Query: 525 ELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVH 584
+LIEK +G+ +++ EE FP+ATD++ KL+ QH ++ + KP+ A +F + H
Sbjct: 494 DLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRVAVN----NFGVKH 548
Query: 585 YAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKK 644
YAG V Y++ G L+KN+D + ++ L ++S + LF E + K
Sbjct: 549 YAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF------EHVSSRNNQDTLKC 602
Query: 645 GSSFQ--TVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGV 702
GS + TVS+ F+++L+ LM L S++P FVRCI PN K P + +VL+QLR +G+
Sbjct: 603 GSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGM 662
Query: 703 LEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFIDSKKASEKLLGSIEIDHTQYK 761
LE +RI + G+ R + DF +RYKVL + A+PE D + LL + +++++
Sbjct: 663 LETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSLLQLYDASNSEWQ 718
Query: 762 FGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYN 821
G TKVF + L LE+ R+E+++ +A GFL R ++RK++ + IQ N
Sbjct: 719 LGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL---YCVVIIQKN 775
Query: 822 IRAFMNVKHWPWMK-----LYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKE 876
RAF+ + + +K +++ + + +A +E+ EK K+E E ++K+
Sbjct: 776 YRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQE----EEEKKK 831
Query: 877 LEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936
EE+ +E+ + +L+ Q E + E Q K Q EA++ E+ ++ +++
Sbjct: 832 REEEERERERERREAELRAQQEEETRKQQELEALQ----KSQKEAELTRELEKQKENKQV 887
Query: 937 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
E+ ++++ED + K+ +L LT A ++K + + +++ L EE
Sbjct: 888 E-EILRLEKEIED--LQRMKEQQELSLTEASLQKLQERRDQELRRLEEE 933
Score = 48.5 bits (114), Expect = 6e-05
Identities = 69/296 (23%), Positives = 134/296 (45%), Gaps = 47/296 (15%)
Query: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKI 917
++F K + L + A +++ K +L+Q L DA QL KTK+
Sbjct: 680 QDFYKRYKVLMRNLALPEDVRGKCTSLLQ---------------LYDASNSEWQLGKTKV 724
Query: 918 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 977
L +++ E+ +EE +A + + L +K + + ++K A
Sbjct: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKVLYCVVIIQKNYRAFLL 781
Query: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDD 1037
+ + L + A + + + + + ++Q L + + +E+K + K K E++
Sbjct: 782 RRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEE--- 835
Query: 1038 LEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKK--KEFEMSN-L 1094
+ ER + + E +L+ QE E KQQ E L+K KE E++ L
Sbjct: 836 -------------ERERERERREAELRAQQEE----ETRKQQELEALQKSQKEAELTREL 878
Query: 1095 QGKIEDEQALAI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
+ + E++Q I +L+K+I++LQ R++E ++E+ AS K +++R R LEE
Sbjct: 879 EKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQERRDQELRRLEE 932
Score = 44.7 bits (104), Expect = 0.001
Identities = 53/215 (24%), Positives = 95/215 (44%), Gaps = 26/215 (12%)
Query: 1284 LHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHD 1343
LH + Q + + ++ R A ++ EE K+Q EEE K + + R +
Sbjct: 786 LHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERRE 845
Query: 1344 CDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKL--AQRL 1401
+ LR Q EEE + EL+ + K+ E R + ++ EE+ +K++ QR+
Sbjct: 846 AE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRM 903
Query: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDK--KQRNFDKVLAE 1459
++ +E ++ ASL+K ++R E+ L AC A + + NFD++
Sbjct: 904 KEQQE----LSLTEASLQKLQERRDQELRRL------EEEACRAAQEFLESLNFDEI--- 950
Query: 1460 WKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494
+E +E S S+EL ++A EE
Sbjct: 951 -----DECVRNIERSLSVGSEFSSEL--AESACEE 978
Score = 41.6 bits (96), Expect = 0.008
Identities = 45/182 (24%), Positives = 79/182 (43%), Gaps = 23/182 (12%)
Query: 1054 RAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQAL-------AI 1106
R R+L + + +E E +K++ E+ +++E E + + + E+ A+
Sbjct: 806 RVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEAL 865
Query: 1107 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
Q +K EL +E+ +E + E R EK+ DL R E+ L EA
Sbjct: 866 QKSQKEAELTRELEKQKENKQVEEILRL--EKEIEDLQRMKEQQELSLTEA--------S 915
Query: 1167 MNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKS 1226
+ K +E RRD E L+ EA AA + + E+ E + +++R + S
Sbjct: 916 LQKLQE------RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSS 969
Query: 1227 EL 1228
EL
Sbjct: 970 EL 971
Score = 40.4 bits (93), Expect = 0.017
Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 10/125 (8%)
Query: 1820 EARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKV 1879
E R +E + + E E+K E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
Query: 1880 KAYKRQAEEAEEQSNVNLAKFRKLQHELEE-----AKERADIAESQVNKLRVKSREVHTK 1934
K + E +++ N + + +L+ E+E+ ++ + E+ + KL+ + R+ +
Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928
Query: 1935 VISEE 1939
+ EE
Sbjct: 929 RLEEE 933
Score = 40.0 bits (92), Expect = 0.022
Identities = 38/132 (28%), Positives = 71/132 (53%), Gaps = 12/132 (9%)
Query: 918 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 977
QL A+ +E E+ + EEE +K+K E+E E +++ + EL + E+ + E
Sbjct: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862
Query: 978 KVKNLTEEMAGLDETIAKLTKEKKALQE--AHQQTLDDLQ-MEEDKVNTLTKAK-TKLEQ 1033
+ +++ A L + K KE K ++E ++ ++DLQ M+E + +LT+A KL++
Sbjct: 863 EALQKSQKEAELTRELEK-QKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQE 921
Query: 1034 QVDDLEGSLEQE 1045
+ D LE+E
Sbjct: 922 RRDQELRRLEEE 933
Score = 37.4 bits (85), Expect = 0.14
Identities = 37/149 (24%), Positives = 73/149 (48%), Gaps = 17/149 (11%)
Query: 1448 KKQRNFDKVLAEWKQKYEETQ---AELEASQKESRSLSTELFKVKNAYEESLDHLETLKR 1504
KKQ +K E +++ E + AEL A Q+E EL ++ + +E+ + L++
Sbjct: 822 KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEK 880
Query: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564
+ +N Q E+I K I +L+++K+Q E S + SL++ + E + ++ R
Sbjct: 881 QKENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRR 929
Query: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRN 1593
++ E + E + +E+D+ RN
Sbjct: 930 LEEEACRAAQEFLESL--NFDEIDECVRN 956
Score = 35.4 bits (80), Expect = 0.55
Identities = 31/179 (17%), Positives = 85/179 (47%), Gaps = 22/179 (12%)
Query: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKK 1775
R + LH + +++ K Q++G++ V AE++ ++ E+ K+
Sbjct: 782 RRRFLHLKKAAIVFQK--------QLRGQIARRVYRQLLAEKREQE---------EKKKQ 824
Query: 1776 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQK 1835
E++ E ++ E+ ++ +LR + E+ +++++ L+ +E E E E++
Sbjct: 825 EEEEKKKREEEERERERERREAELRAQQEEETR---KQQELEALQKSQKEAELTRELEKQ 881
Query: 1836 HNVEAVKGLRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQTKVKAYKRQAEEAEEQ 1892
+ V+ + + E+ +++L E+ ++ LQ L ++ +++ + +A A ++
Sbjct: 882 KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 473 bits (1217), Expect = e-133
Identities = 321/930 (34%), Positives = 490/930 (52%), Gaps = 82/930 (8%)
Query: 80 MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
M+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+PE
Sbjct: 59 MHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEH 118
Query: 140 VTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 119 IRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA-- 176
Query: 200 AVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATG 259
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF G
Sbjct: 177 AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRG 225
Query: 260 KLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG 319
+ A IE YLLEKSRV Q ER+YH+FY +L + + L + D+ +++ G
Sbjct: 226 AIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMG 284
Query: 320 E-ITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQRE--EQA 376
IT D +E SA+ +L FT E I KL A++H GN++++ + E +
Sbjct: 285 NCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDAC 344
Query: 377 EPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV------QQVYNAVGAL 430
E + AA L +N DL+ L +T+G+TV +Q + A
Sbjct: 345 EVLFSPSLATAASLLEVNPPDLMSCL------TSRTLITRGETVSTPLSREQALDVRDAF 398
Query: 431 AKAIYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
K IY ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF
Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457
Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP
Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517
Query: 545 KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPL 604
K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L
Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573
Query: 605 NETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664
+ ++ L S K + +F +A+ G + K+ T+S+ F+ +L LM
Sbjct: 574 HGDIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMR 623
Query: 665 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724
L + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +
Sbjct: 624 TLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVE 683
Query: 725 RYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEK 784
RY+VL P + D + +++ ++ H ++ G TK+F K LE RD+
Sbjct: 684 RYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKA 743
Query: 785 LAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKL-YFKIKPL 843
+ + Q + RGF R F K+ + + IQ + R K++ M+L + +++ L
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQAL 800
Query: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADAL 902
+S + + +++ ++ + + +A+ R L K ++ L + +A A
Sbjct: 801 HRSRK-------LHQQYRLARQRIIQFQARCRAYLVRKAF-----RHRLWAVLTVQAYAR 848
Query: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKK 956
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L +
Sbjct: 849 GMIARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Query: 957 DIDDLELTLAKVEKEKHATENKVKNLTEEM 986
+ + EL KEK A K K L E+M
Sbjct: 907 EDAEREL------KEKEAARRK-KELLEQM 929
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 473 bits (1217), Expect = e-133
Identities = 321/930 (34%), Positives = 490/930 (52%), Gaps = 82/930 (8%)
Query: 80 MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
M+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+PE
Sbjct: 59 MHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEH 118
Query: 140 VTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 119 IRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA-- 176
Query: 200 AVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATG 259
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF G
Sbjct: 177 AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRG 225
Query: 260 KLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG 319
+ A IE YLLEKSRV Q ER+YH+FY +L + + L + D+ +++ G
Sbjct: 226 AIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMG 284
Query: 320 E-ITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQRE--EQA 376
IT D +E SA+ +L FT E I KL A++H GN++++ + E +
Sbjct: 285 NCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDAC 344
Query: 377 EPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV------QQVYNAVGAL 430
E + AA L +N DL+ L +T+G+TV +Q + A
Sbjct: 345 EVLFSPSLATAASLLEVNPPDLMSCL------TSRTLITRGETVSTPLSREQALDVRDAF 398
Query: 431 AKAIYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
K IY ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF
Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457
Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP
Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517
Query: 545 KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPL 604
K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L
Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573
Query: 605 NETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664
+ ++ L S K + +F +A+ G + K+ T+S+ F+ +L LM
Sbjct: 574 HGDIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMR 623
Query: 665 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724
L + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +
Sbjct: 624 TLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVE 683
Query: 725 RYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEK 784
RY+VL P + D + +++ ++ H ++ G TK+F K LE RD+
Sbjct: 684 RYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKA 743
Query: 785 LAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKL-YFKIKPL 843
+ + Q + RGF R F K+ + + IQ + R K++ M+L + +++ L
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQAL 800
Query: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADAL 902
+S + + +++ ++ + + +A+ R L K ++ L + +A A
Sbjct: 801 HRSRK-------LHQQYRLARQRIIQFQARCRAYLVRKAF-----RHRLWAVLTVQAYAR 848
Query: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKK 956
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L +
Sbjct: 849 GMIARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Query: 957 DIDDLELTLAKVEKEKHATENKVKNLTEEM 986
+ + EL KEK A K K L E+M
Sbjct: 907 EDAEREL------KEKEAARRK-KELLEQM 929
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 473 bits (1217), Expect = e-133
Identities = 321/930 (34%), Positives = 490/930 (52%), Gaps = 82/930 (8%)
Query: 80 MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
M+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y+PE
Sbjct: 59 MHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEH 118
Query: 140 VTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
+ Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A
Sbjct: 119 IRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA-- 176
Query: 200 AVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATG 259
A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF G
Sbjct: 177 AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRG 225
Query: 260 KLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQG 319
+ A IE YLLEKSRV Q ER+YH+FY +L + + L + D+ +++ G
Sbjct: 226 AIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMG 284
Query: 320 E-ITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQRE--EQA 376
IT D +E SA+ +L FT E I KL A++H GN++++ + E +
Sbjct: 285 NCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDAC 344
Query: 377 EPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV------QQVYNAVGAL 430
E + AA L +N DL+ L +T+G+TV +Q + A
Sbjct: 345 EVLFSPSLATAASLLEVNPPDLMSCL------TSRTLITRGETVSTPLSREQALDVRDAF 398
Query: 431 AKAIYEKMFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
K IY ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF
Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFA 457
Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
NE LQQFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FP
Sbjct: 458 NEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP 517
Query: 545 KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPL 604
K TDT+ +KL QH +N P K E F + H+AG V Y G+L+KN+D L
Sbjct: 518 KGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGINHFAGIVYYETQGFLEKNRDTL 573
Query: 605 NETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664
+ ++ L S K + +F +A+ G + K+ T+S+ F+ +L LM
Sbjct: 574 HGDIIQLVHSSRNKFIKQIF------QADVAMGAETRKRS----PTLSSQFKRSLELLMR 623
Query: 665 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724
L + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +
Sbjct: 624 TLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVE 683
Query: 725 RYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEK 784
RY+VL P + D + +++ ++ H ++ G TK+F K LE RD+
Sbjct: 684 RYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKA 743
Query: 785 LAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKL-YFKIKPL 843
+ + Q + RGF R F K+ + + IQ + R K++ M+L + +++ L
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQAL 800
Query: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAK-RKELEEKMVTLMQEKNDLQLQVQAEADAL 902
+S + + +++ ++ + + +A+ R L K ++ L + +A A
Sbjct: 801 HRSRK-------LHQQYRLARQRIIQFQARCRAYLVRKAF-----RHRLWAVLTVQAYAR 848
Query: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKK 956
R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L +
Sbjct: 849 GMIARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Query: 957 DIDDLELTLAKVEKEKHATENKVKNLTEEM 986
+ + EL KEK A K K L E+M
Sbjct: 907 EDAEREL------KEKEAARRK-KELLEQM 929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,755,542
Number of Sequences: 37866
Number of extensions: 2911901
Number of successful extensions: 60984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 819
Number of HSP's successfully gapped in prelim test: 1607
Number of HSP's that attempted gapping in prelim test: 13665
Number of HSP's gapped (non-prelim): 16001
length of query: 1939
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1822
effective length of database: 13,817,196
effective search space: 25174931112
effective search space used: 25174931112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.