BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|167466201 WAS protein family homolog 1 [Homo sapiens] (465 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|167466201 WAS protein family homolog 1 [Homo sapiens] 923 0.0 gi|239743666 PREDICTED: hypothetical protein XP_002342940 isofor... 903 0.0 gi|239743664 PREDICTED: hypothetical protein XP_002342939 isofor... 897 0.0 gi|110431370 espin [Homo sapiens] 62 1e-09 gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 55 1e-07 gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07 gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07 gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 2e-07 gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 54 2e-07 gi|33356148 formin-like 1 [Homo sapiens] 54 4e-07 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 52 9e-07 gi|7706687 Enah/Vasp-like [Homo sapiens] 52 1e-06 gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 51 3e-06 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 51 3e-06 gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 50 3e-06 gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 50 4e-06 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 50 6e-06 gi|153792074 proline rich 12 [Homo sapiens] 50 6e-06 gi|157168329 formin 1 [Homo sapiens] 49 1e-05 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 49 1e-05 gi|52485606 formin-like 2 [Homo sapiens] 49 1e-05 gi|11386183 WAS protein family, member 2 [Homo sapiens] 49 1e-05 gi|55953110 retinoblastoma protein-binding zinc finger protein i... 49 1e-05 gi|20336260 retinoblastoma protein-binding zinc finger protein i... 49 1e-05 gi|20336258 retinoblastoma protein-binding zinc finger protein i... 49 1e-05 gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 48 2e-05 gi|110832843 TBP-associated factor 4 [Homo sapiens] 48 2e-05 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 48 2e-05 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 47 3e-05 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 46 6e-05 >gi|167466201 WAS protein family homolog 1 [Homo sapiens] Length = 465 Score = 923 bits (2385), Expect = 0.0 Identities = 465/465 (100%), Positives = 465/465 (100%) Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS Sbjct: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60 Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR Sbjct: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120 Query: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE Sbjct: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180 Query: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ Sbjct: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240 Query: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV Sbjct: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300 Query: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG Sbjct: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360 Query: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR Sbjct: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420 Query: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES Sbjct: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465 >gi|239743666 PREDICTED: hypothetical protein XP_002342940 isoform 2 [Homo sapiens] Length = 465 Score = 903 bits (2333), Expect = 0.0 Identities = 455/465 (97%), Positives = 459/465 (98%) Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60 MTPVRMQHSLAGQTYAVP IQPDLRREEAVQQMADALQYLQKVSGDIFSRISQ+VEQSRS Sbjct: 1 MTPVRMQHSLAGQTYAVPFIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRS 60 Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAP RLQEYGSIFTGAQDPGLQRRPR Sbjct: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPGRLQEYGSIFTGAQDPGLQRRPR 120 Query: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE Sbjct: 121 HRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTE 180 Query: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ Sbjct: 181 NLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQ 240 Query: 241 VPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300 VPEI VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV Sbjct: 241 VPEIHVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGV 300 Query: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG Sbjct: 301 LTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360 Query: 361 GRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRR 420 G ATLLESIRQAGGIGKAKLRS+KERKLEK++QKEQEQVRATSQGG LMSDLFNKLVMRR Sbjct: 361 GWATLLESIRQAGGIGKAKLRSMKERKLEKQQQKEQEQVRATSQGGHLMSDLFNKLVMRR 420 Query: 421 KGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465 KGISGKGPGAGEGPGGAF RVSDSIPPLPPPQQPQAEEDEDDWES Sbjct: 421 KGISGKGPGAGEGPGGAFVRVSDSIPPLPPPQQPQAEEDEDDWES 465 >gi|239743664 PREDICTED: hypothetical protein XP_002342939 isoform 1 [Homo sapiens] Length = 482 Score = 897 bits (2319), Expect = 0.0 Identities = 455/468 (97%), Positives = 459/468 (98%), Gaps = 3/468 (0%) Query: 1 MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQRVEQSRS 60 MTPVRMQHSLAGQTYAVP IQPDLRREEAVQQMADALQYLQKVSGDIFSRISQ+VEQSRS Sbjct: 15 MTPVRMQHSLAGQTYAVPFIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRS 74 Query: 61 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPR 120 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAP RLQEYGSIFTGAQDPGLQRRPR Sbjct: 75 QVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPGRLQEYGSIFTGAQDPGLQRRPR 134 Query: 121 HRIQSKHRPLDERALQ---EKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN 177 HRIQSKHRPLDERALQ EKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN Sbjct: 135 HRIQSKHRPLDERALQPSQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFN 194 Query: 178 TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD 237 TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD Sbjct: 195 TTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPD 254 Query: 238 LGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ 297 LGQVPEI VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ Sbjct: 255 LGQVPEIHVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQ 314 Query: 298 DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357 DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD Sbjct: 315 DGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 374 Query: 358 PSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLV 417 PSGG ATLLESIRQAGGIGKAKLRS+KERKLEK++QKEQEQVRATSQGG LMSDLFNKLV Sbjct: 375 PSGGWATLLESIRQAGGIGKAKLRSMKERKLEKQQQKEQEQVRATSQGGHLMSDLFNKLV 434 Query: 418 MRRKGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 465 MRRKGISGKGPGAGEGPGGAF RVSDSIPPLPPPQQPQAEEDEDDWES Sbjct: 435 MRRKGISGKGPGAGEGPGGAFVRVSDSIPPLPPPQQPQAEEDEDDWES 482 >gi|110431370 espin [Homo sapiens] Length = 854 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/99 (38%), Positives = 46/99 (46%), Gaps = 5/99 (5%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPV 331 PSAP LP H V D + PPPPPPPPPP PE +S PP PP Sbjct: 567 PSAPPQAALLPGNH--VPNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLPLESA 624 Query: 332 GQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIR 370 G G Q SSSS + ++ P+G + LL I+ Sbjct: 625 GPGCGQRRSSSSTGST---KSFNMMSPTGDNSELLAEIK 660 Score = 37.7 bits (86), Expect = 0.022 Identities = 20/41 (48%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 299 GVLTPPPPPP----PPPPAPEVLASAPPLPPSTAAPVGQGA 335 G TPPPPPP PPPP L PP P+ PVG A Sbjct: 426 GKPTPPPPPPSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQA 466 Score = 34.7 bits (78), Expect = 0.19 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 293 KVDLQDGVLTPPPPPPP----PPPAPEVLASAPPLPPSTAAP 330 ++ L G + P PPPP PPP P PP PP AP Sbjct: 417 ELGLPRGTIGKPTPPPPPPSFPPPPPPPGTQLPPPPPGYPAP 458 Score = 32.3 bits (72), Expect = 0.94 Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 3/29 (10%) Query: 303 PPPPPP---PPPPAPEVLASAPPLPPSTA 328 PPPPPP PPP P A PP+ P A Sbjct: 439 PPPPPPGTQLPPPPPGYPAPKPPVGPQAA 467 Score = 29.3 bits (64), Expect = 7.9 Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 28/102 (27%) Query: 301 LTPPPPPPPPPPA--PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358 L+P P PP P + S P+PP+T AP G + D + + QG P Sbjct: 699 LSPVRSPTPPAAGFQPLLNGSLVPVPPTTPAP---GVQLDVEALIPTHDEQGRP------ 749 Query: 359 SGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVR 400 I + K R V RK++ K Q+E+EQ R Sbjct: 750 ----------------IPEWK-RQVMVRKMQLKMQEEEEQRR 774 >gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] Length = 1499 Score = 55.1 bits (131), Expect = 1e-07 Identities = 56/195 (28%), Positives = 75/195 (38%), Gaps = 28/195 (14%) Query: 271 APSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAP 330 AP P T LP P PPP PPPPPPAP SAPP P P Sbjct: 279 APKVPPTPEPLPLSTPSAGTPQS--------QPPPLPPPPPPAP---GSAPPALPPEGPP 327 Query: 331 VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGG----------IGKAKL 380 + + QD + +S + G P+ AT + GG +G+A Sbjct: 328 --EDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAA 385 Query: 381 RSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISG--KGP--GAGEGPGG 436 +R L + +EQ+ + + D+ +L++R KGP GAGEG Sbjct: 386 PGNGQRSLVGSEGLSKEQLEHRERSLQTLRDI-ERLLLRSGETEPFLKGPPGGAGEGGPP 444 Query: 437 AFARVSDSIPPLPPP 451 A A PP PP Sbjct: 445 AQAPPPPQQPPTAPP 459 Score = 53.1 bits (126), Expect = 5e-07 Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 21/177 (11%) Query: 290 EPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQ 349 EPL + PPP PPP P SAPP P P + + QD + +S + Sbjct: 287 EPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPP--EDSSQDLAPNSVGAAST 344 Query: 350 GAPREVVDPSGGRATLLESIRQAGG----------IGKAKLRSVKERKLEKKKQKEQEQV 399 G P+ AT + GG +G+A +R L + +EQ+ Sbjct: 345 GGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQL 404 Query: 400 RATSQGGDLMSDLFNKLVMRRKGISG--KGPGAGEGPGGAFARVSDSIPPLPPPQQP 454 + + D+ +L++R KGP G G GG A+ PPPQQP Sbjct: 405 EHRERSLQTLRDI-ERLLLRSGETEPFLKGPPGGAGEGGPPAQAP------PPPQQP 454 >gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305 DL +S LG + P+ PG +P +P F + + L+ PPP Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655 Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363 PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714 Query: 364 TLLESI 369 ESI Sbjct: 715 GSSESI 720 Score = 33.1 bits (74), Expect = 0.55 Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%) Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347 P +++ PPP P PPPA P V+ + + PV S + Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464 Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404 V AP + P G TL + Q G A R V R + + V T Q Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521 Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446 G L +S L +L+M+ ++ PG P A A S Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581 Query: 447 ---PLPPPQQPQ 455 P PP PQ Sbjct: 582 PGGPAQPPPTPQ 593 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314 P P PE ++ +EP++ + Q+ LTP P P P PAP Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257 Query: 315 EVLASAPPLP 324 E A P P Sbjct: 258 ETNAPNHPSP 267 Score = 29.6 bits (65), Expect = 6.1 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352 PPP P A APP P A+ V + +SS+ +P AP Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428 Score = 29.3 bits (64), Expect = 7.9 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%) Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350 PPP PP P P L+S APP P A V + A + + P+ G Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252 >gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305 DL +S LG + P+ PG +P +P F + + L+ PPP Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655 Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363 PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714 Query: 364 TLLESI 369 ESI Sbjct: 715 GSSESI 720 Score = 33.1 bits (74), Expect = 0.55 Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%) Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347 P +++ PPP P PPPA P V+ + + PV S + Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464 Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404 V AP + P G TL + Q G A R V R + + V T Q Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521 Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446 G L +S L +L+M+ ++ PG P A A S Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581 Query: 447 ---PLPPPQQPQ 455 P PP PQ Sbjct: 582 PGGPAQPPPTPQ 593 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314 P P PE ++ +EP++ + Q+ LTP P P P PAP Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257 Query: 315 EVLASAPPLP 324 E A P P Sbjct: 258 ETNAPNHPSP 267 Score = 29.6 bits (65), Expect = 6.1 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352 PPP P A APP P A+ V + +SS+ +P AP Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428 Score = 29.3 bits (64), Expect = 7.9 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%) Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350 PPP PP P P L+S APP P A V + A + + P+ G Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252 >gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305 DL +S LG + P+ PG +P +P F + + L+ PPP Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 655 Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363 PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA Sbjct: 656 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 714 Query: 364 TLLESI 369 ESI Sbjct: 715 GSSESI 720 Score = 33.1 bits (74), Expect = 0.55 Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%) Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347 P +++ PPP P PPPA P V+ + + PV S + Sbjct: 409 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 464 Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404 V AP + P G TL + Q G A R V R + + V T Q Sbjct: 465 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 521 Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446 G L +S L +L+M+ ++ PG P A A S Sbjct: 522 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 581 Query: 447 ---PLPPPQQPQ 455 P PP PQ Sbjct: 582 PGGPAQPPPTPQ 593 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314 P P PE ++ +EP++ + Q+ LTP P P P PAP Sbjct: 198 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 257 Query: 315 EVLASAPPLP 324 E A P P Sbjct: 258 ETNAPNHPSP 267 Score = 29.6 bits (65), Expect = 6.1 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352 PPP P A APP P A+ V + +SS+ +P AP Sbjct: 388 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428 Score = 29.3 bits (64), Expect = 7.9 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%) Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350 PPP PP P P L+S APP P A V + A + + P+ G Sbjct: 196 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 252 >gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] Length = 1132 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 259 DLMYSADLGPGIAPSAPGT-------------IPELPTFHTEVAEPLKVDLQDGVLTPPP 305 DL +S LG + P+ PG +P +P F + + L+ PPP Sbjct: 604 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT--QTAPPPPP 661 Query: 306 PPPPPPPAPEVLASAPPLPPSTAA--PVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363 PPPPPPPAPE PP PS A P G G + S + VQG ++ G RA Sbjct: 662 PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL-ESLSPEFFTSVVQGVLSSLLGSLGARA 720 Query: 364 TLLESI 369 ESI Sbjct: 721 GSSESI 726 Score = 33.1 bits (74), Expect = 0.55 Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 34/192 (17%) Query: 291 PLKVDLQDGVLTPPPPPPPPPPA---PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPS 347 P +++ PPP P PPPA P V+ + + PV S + Sbjct: 415 PSSTNVESSAEGAPPPGPAPPPATSHPRVIR----ISHQSVEPVVMMHMNIQDSGTQPGG 470 Query: 348 VQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQ---EQVRATSQ 404 V AP + P G TL + Q G A R V R + + V T Q Sbjct: 471 VPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQ 527 Query: 405 GGDL---------MSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIP--------- 446 G L +S L +L+M+ ++ PG P A A S Sbjct: 528 GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA 587 Query: 447 ---PLPPPQQPQ 455 P PP PQ Sbjct: 588 PGGPAQPPPTPQ 599 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 17/70 (24%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDL-----------------QDGVLTPPPPPPPPPPAP 314 P P PE ++ +EP++ + Q+ LTP P P P PAP Sbjct: 204 PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAP 263 Query: 315 EVLASAPPLP 324 E A P P Sbjct: 264 ETNAPNHPSP 273 Score = 29.6 bits (65), Expect = 6.1 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 310 PPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAP 352 PPP P A APP P A+ V + +SS+ +P AP Sbjct: 394 PPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP 434 Score = 29.3 bits (64), Expect = 7.9 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 9/57 (15%) Query: 303 PPPPPPPPPPAPEVLAS---------APPLPPSTAAPVGQGARQDDSSSSASPSVQG 350 PPP PP P P L+S APP P A V + A + + P+ G Sbjct: 202 PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAG 258 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/129 (32%), Positives = 51/129 (39%), Gaps = 23/129 (17%) Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVA------ 289 P G P VP+ P + DL +A+ PG AP P +P LP+ Sbjct: 511 PSGGDAPTPGVPTGSP-----SPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA 565 Query: 290 -------EPLKVDLQDGVLTPPPPPPPPPPAPE--VLASAPPLPPSTAAPVGQGARQDDS 340 EP G L PPPPPPPPPP + V PP PP P R+D Sbjct: 566 PPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRD-- 623 Query: 341 SSSASPSVQ 349 S P V+ Sbjct: 624 -SELGPGVK 631 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 52.4 bits (124), Expect = 9e-07 Identities = 55/217 (25%), Positives = 78/217 (35%), Gaps = 35/217 (16%) Query: 267 GPGIAPS-APGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPP----PPPPPA-PEVLASA 320 GP P+ G P P+ A P + V PPPPP PPPPPA P S Sbjct: 298 GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSG 357 Query: 321 PPLPPSTAAPVGQGARQDDSSSSASPSVQGAP-------REVVDPSGGRATLLESIRQAG 373 PP PP + VG A P P +V +G +A LL+ IR+ Sbjct: 358 PPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGA 417 Query: 374 GIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGK-----GP 428 + K+ EQ + G D + D + + + G+ P Sbjct: 418 QL----------------KKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTP 461 Query: 429 GAGEGPGGAFARVSDS-IPPLPPPQQPQAEEDEDDWE 464 G GA V + + + E+DE+D+E Sbjct: 462 APTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFE 498 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/35 (60%), Positives = 21/35 (60%), Gaps = 7/35 (20%) Query: 303 PPPPPPP----PPPAPEVLASAPPLPPS---TAAP 330 PPPPPPP PPP P APP PPS TAAP Sbjct: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322 Score = 37.0 bits (84), Expect = 0.038 Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 8/37 (21%) Query: 303 PPPPPP----PPPPAPEVLASAPPLPPSTAAPVGQGA 335 PPPPPP PPPP P S PP PP+ G+GA Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPAR----GRGA 309 >gi|7706687 Enah/Vasp-like [Homo sapiens] Length = 418 Score = 51.6 bits (122), Expect = 1e-06 Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 28/150 (18%) Query: 277 TIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGAR 336 T P LP H A V PPPPPPPP P P A+ PP PP A QG+ Sbjct: 162 TGPILPPGHPSSAASAPVSCSG----PPPPPPPPVPPPPTGATPPP-PPPLPAGGAQGSS 216 Query: 337 QDDSS-SSASPSVQGAPREVV----DPSGGRA----TLLESIRQAGGIG----------- 376 D+SS S + ++ GA V D SGG + + ++ R + G G Sbjct: 217 HDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL 276 Query: 377 ---KAKLRSVKERKLEKKKQKEQEQVRATS 403 + K S ++ EKK+ + Q + +TS Sbjct: 277 LAKRRKAASQSDKPAEKKEDESQMEDPSTS 306 >gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] Length = 380 Score = 50.8 bits (120), Expect = 3e-06 Identities = 42/132 (31%), Positives = 52/132 (39%), Gaps = 13/132 (9%) Query: 293 KVDLQDGVLTPP---PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQ 349 +V G PP PPPPP PP P P LPPS GA + P+ Q Sbjct: 155 RVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQ 214 Query: 350 GAPREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLM 409 G P GG A + A I AKLR V +++ + S GG LM Sbjct: 215 G-------PGGGGA---GAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLM 264 Query: 410 SDLFNKLVMRRK 421 ++ L RRK Sbjct: 265 EEMNAMLARRRK 276 Score = 30.0 bits (66), Expect = 4.7 Identities = 25/93 (26%), Positives = 32/93 (34%) Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRAT 364 PPP PP PA + P AA + + S + AP+ SGG Sbjct: 204 PPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGL 263 Query: 365 LLESIRQAGGIGKAKLRSVKERKLEKKKQKEQE 397 + E KA K K E Q+E E Sbjct: 264 MEEMNAMLARRRKATQVGEKTPKDESANQEEPE 296 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 50.8 bits (120), Expect = 3e-06 Identities = 46/156 (29%), Positives = 61/156 (39%), Gaps = 11/156 (7%) Query: 303 PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGR 362 PPPPPPP PP P L APP PP +A PV D+SS +G + D G Sbjct: 4 PPPPPPPLPPPPPPL-GAPPPPPPSAPPV-----STDTSSLRRADPKGRSALLADIQQG- 56 Query: 363 ATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKL-VMRRK 421 T L + Q ++ S K E GDL + F L ++ Sbjct: 57 -TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115 Query: 422 GISGKGPGAGEGPGGAFARVSDSI--PPLPPPQQPQ 455 ++G G G G R+ + PL PP P+ Sbjct: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPR 151 Score = 45.8 bits (107), Expect = 8e-05 Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 18/93 (19%) Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLG-PGIAPSAPGTIPELPTFHTEVAEPLKV 294 P VP P+ P P + L S+ + P ++P P T LP VA P+ Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV----VAPPVPC 221 Query: 295 DLQDGVLTPPPPPPPPPPAPEVLASAPPLPPST 327 PPPPPPPPPP P PPLPP++ Sbjct: 222 -------APPPPPPPPPPTP------PPLPPAS 241 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/131 (30%), Positives = 49/131 (37%), Gaps = 21/131 (16%) Query: 235 VPDLGQVPEIDVPSYLPDLP--GIANDLMYSADLGPGIAPSAPGTIPELPT-----FHTE 287 VP P P P LP + +D L P P P +P LP E Sbjct: 219 VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278 Query: 288 VAEPLKVDLQDGVLTPPPPPPPPPP----APEVLASAPPLPPSTAAPVGQGARQDDSSSS 343 A P + D Q+ PP PPPP PP +P APPLP V + Sbjct: 279 PASPAQ-DAQE----PPAPPPPLPPYASCSPRASLPAPPLP-----GVNSSSETPPPLPP 328 Query: 344 ASPSVQGAPRE 354 SPS Q P++ Sbjct: 329 KSPSFQAPPQK 339 Score = 39.3 bits (90), Expect = 0.008 Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 15/96 (15%) Query: 239 GQVPEIDVPSYLPDLPG--IANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDL 296 GQ P PS P LP I+ L+ A G A G P A P Sbjct: 123 GQGPGSRAPS--PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP----- 175 Query: 297 QDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVG 332 PP PPPPPPP P L S+ P+ +P G Sbjct: 176 ------PPTPPPPPPPLPPPLPSSSPIKTPLVSPPG 205 Score = 30.0 bits (66), Expect = 4.7 Identities = 22/88 (25%), Positives = 31/88 (35%), Gaps = 9/88 (10%) Query: 252 DLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPP- 310 +LP +A + + P P P +P + +P L + PP P PP Sbjct: 211 NLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC 270 Query: 311 --------PPAPEVLASAPPLPPSTAAP 330 P +P A PP PP P Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPP 298 >gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] Length = 547 Score = 50.4 bits (119), Expect = 3e-06 Identities = 42/143 (29%), Positives = 60/143 (41%), Gaps = 25/143 (17%) Query: 268 PGIAPS-APGTIPELPT-FHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPP 325 P ++P +P + P+LP T + PL V TPPPPPPPPPP P PP PP Sbjct: 389 PYVSPRHSPWSSPKLPKKVQTVRSRPLSP-----VATPPPPPPPPPPPPPSSQRLPPPPP 443 Query: 326 STAAP----------VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGI 375 P + + +Q +S+ A + Q + + L E Sbjct: 444 PPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEI------- 496 Query: 376 GKAKLRSVKERKLEKKKQKEQEQ 398 K LRSV+E+K+E + Q Sbjct: 497 -KNSLRSVQEKKMEDSSRPSTPQ 518 >gi|167234419 thyroid hormone receptor associated protein 3 [Homo sapiens] Length = 955 Score = 50.1 bits (118), Expect = 4e-06 Identities = 56/188 (29%), Positives = 76/188 (40%), Gaps = 24/188 (12%) Query: 287 EVAEPLKVDLQDGVLT-----PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQ-DDS 340 E + LK LQ V+ P P P P PP LP G Q D Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305 Query: 341 SSSASPSVQGAPREVVDPSGGR---ATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQE 397 S S SPS + +P PS G ++ E +GG K R ++E+K E K KEQ+ Sbjct: 306 SGSLSPSKK-SPVGKSPPSTGSTYGSSQKEESAASGGAAYTK-RYLEEQKTENGKDKEQK 363 Query: 398 QVRATSQGGDLMSDLFNKLVMRRKG-ISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQA 456 Q +K ++ KG S G G G+ +FA +DS P Q P+ Sbjct: 364 QTNT------------DKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKR 411 Query: 457 EEDEDDWE 464 + DD+E Sbjct: 412 YKLRDDFE 419 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 49.7 bits (117), Expect = 6e-06 Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 9/95 (9%) Query: 246 VPSYLPDLPGIANDLMYSADLGPGIAPSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPP 304 VP LP LP S P IAP+ P T P +P EP ++ G L PP Sbjct: 791 VPEGLPPLPPPPP----SGATPPPIAPTGPPTASPPVPAKE----EPEELPAAPGPLPPP 842 Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDD 339 PPPPPP P P L +P T G A ++D Sbjct: 843 PPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED 877 Score = 43.9 bits (102), Expect = 3e-04 Identities = 55/190 (28%), Positives = 76/190 (40%), Gaps = 40/190 (21%) Query: 244 IDVPSYLPDLPGIANDLMYSADLGPGIAPSA--PGTIPELPTFHTEVAEP---------- 291 + VP L LPG N S + P +APS P TIP TF V P Sbjct: 717 VSVPPRL--LPGPENHRAGSNE-DPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEA 773 Query: 292 ------LKVDLQDGVLTPPPPPPPPPPAPEVLASAPPL----PPSTAAPVGQGARQDDSS 341 L+ D D V+ P PP PP P A+ PP+ PP+ + PV A+++ Sbjct: 774 SDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPV--PAKEEPEE 831 Query: 342 SSASPSVQGAPREVVDPSGGRATL----LESIRQAGGIGKAKL---------RSVKERKL 388 A+P P P G TL L GG G L S E + Sbjct: 832 LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEE 891 Query: 389 EKKKQKEQEQ 398 E+++++E+E+ Sbjct: 892 EEEEEEEEEE 901 Score = 32.3 bits (72), Expect = 0.94 Identities = 20/60 (33%), Positives = 21/60 (35%), Gaps = 7/60 (11%) Query: 299 GVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358 G P P P PPP AP + P PP VG S SA P P P Sbjct: 642 GPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVG-------SMPSAGPMPSAGPMPSAGP 694 Score = 29.6 bits (65), Expect = 6.1 Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 295 DLQDGVLTPPPPPP--PPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSV 348 ++++G PP PP PPP +P + P P V + +++ + +P++ Sbjct: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 49.7 bits (117), Expect = 6e-06 Identities = 38/136 (27%), Positives = 51/136 (37%), Gaps = 10/136 (7%) Query: 251 PDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEV---------AEPLKVDLQDGVL 301 P LPG+ + P + P T P PT + A P L Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTP 1493 Query: 302 TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGA-PREVVDPSG 360 + PPPPP PPP P + S PP PP AAP+ + + S P + P + Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQE 1553 Query: 361 GRATLLESIRQAGGIG 376 A E+ +AG G Sbjct: 1554 TAAVCGETDEEAGESG 1569 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/125 (29%), Positives = 49/125 (39%), Gaps = 26/125 (20%) Query: 245 DVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPP 304 D+P LP P L P + AP P + EP +DG PP Sbjct: 789 DLPLVLPPPP---------PQLLPSVLSHAPSPSPSASKVGVHLLEPAT---RDGAPQPP 836 Query: 305 PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRAT 364 PPPPPPP PP+P A + + A+PS + P E +DP G Sbjct: 837 PPPPPPP---------PPMPLQLEAHL-----RSHGLEPAAPSPRLRPEESLDPPGAMQE 882 Query: 365 LLESI 369 LL ++ Sbjct: 883 LLGAL 887 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/88 (39%), Positives = 39/88 (44%), Gaps = 19/88 (21%) Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGT------IPELPTFHTEVA 289 P G P P+Y P P Y G P PG PELP+ T A Sbjct: 974 PKAGAGPPPGPPAYDPYGP-------YCPGRASGAGPETPGLGLDPNKPPELPS--TVNA 1024 Query: 290 EPLKVDLQDG---VLTPPPPPPPPPPAP 314 EPL + +Q G PPPPPPPPPPAP Sbjct: 1025 EPLGL-IQSGPHQAAPPPPPPPPPPPAP 1051 Score = 32.7 bits (73), Expect = 0.72 Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 19/115 (16%) Query: 269 GIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPS-- 326 G AP P LP T + Q PPPPPPP A + S PS Sbjct: 270 GAAPGPPPPERALPRQDTVIKH-----YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324 Query: 327 -----TAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIG 376 +P+G G + S + PS G P + GRAT E+ AGG G Sbjct: 325 HRANLACSPLGGG---EPSPGAGEPSKAG-PSGATAGASGRATGPEA---AGGGG 372 Score = 29.3 bits (64), Expect = 7.9 Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 23/156 (14%) Query: 321 PPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG--GRATLLESIRQAG-GIG- 376 PPL P + P AR A+P+V P PSG G LE+ G G+G Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPP-----PSGAFGLGGALEAAESEGLGLGC 1359 Query: 377 ---KAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKL-VMRRKGISG-KGPGAG 431 +L +R LE ++ + ++ DL + + + + ++G K Sbjct: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419 Query: 432 EGPGGAFARVSDSIPPLP---------PPQQPQAEE 458 +GP A A PPLP P+ P EE Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455 Score = 29.3 bits (64), Expect = 7.9 Identities = 15/37 (40%), Positives = 15/37 (40%), Gaps = 5/37 (13%) Query: 299 GVLTPPPPPPPPPPAPE-----VLASAPPLPPSTAAP 330 G PPP P PPP PE P P TA P Sbjct: 1688 GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP 1724 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 48.9 bits (115), Expect = 1e-05 Identities = 43/168 (25%), Positives = 63/168 (37%), Gaps = 20/168 (11%) Query: 198 KTHVMLGAETEEKLFDAPL-SISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPGI 256 KT + +T+ + F P S SK + Q VP+ ++ + ++ P+ D+ Sbjct: 575 KTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKL----NISSLSQLSPPNDHKDIHAA 630 Query: 257 ANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAE----PLKVDLQDGVLTPPPPPPPPPP 312 + A P P +IP P + + P + G PPPPPPPPP Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690 Query: 313 APEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSG 360 P A PP PP P +S +P G P P G Sbjct: 691 PPPSSAGPPPPPPPPPLP-----------NSPAPPNPGGPPPAPPPPG 727 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/158 (26%), Positives = 51/158 (32%), Gaps = 12/158 (7%) Query: 299 GVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDP 358 G P PPPPPPPAP PP PP A P G G + P + P E D Sbjct: 15 GATPAPGPPPPPPPAPP--QQQPPPPPPPAPPPGPG----PAPPQHPPRAEALPPEAADE 68 Query: 359 SGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVM 418 G R L G G S + + + + Q G + Sbjct: 69 GGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVS---- 124 Query: 419 RRKGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQA 456 G G GPG A S+ P P+ QA Sbjct: 125 --FSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQA 160 Score = 33.1 bits (74), Expect = 0.55 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 15/102 (14%) Query: 265 DLGPGIAPSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVL--ASAP 321 DL G+ + I E+ + E+ + ++ + G+ PPPPPP A L A+A Sbjct: 677 DLNSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAM 736 Query: 322 PLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRA 363 P A P+ P G+PR V P G A Sbjct: 737 SFCPQVARPL------------VGPLALGSPRLVRRPPPGPA 766 Score = 29.3 bits (64), Expect = 7.9 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 26/96 (27%) Query: 283 TFHTEVAEPLKVDLQDG----VLTPPPPPPP-------PPPAPEVLASAPPLPPST---- 327 +F +VA PL L G V PPP P P PPPA A A P P T Sbjct: 737 SFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYG 796 Query: 328 ----------AAPVGQGARQDDSSSSASPSV-QGAP 352 A P + +R S++ PS+ GAP Sbjct: 797 GLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAP 832 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%) Query: 256 IANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPE 315 + ++++ +GP + ++ G +P P ++ + +Q+G +TPP PPPPPPP P Sbjct: 504 MGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPET-VQNGPVTPPMPPPPPPPPPP 562 Query: 316 VLASAPPLPPSTAAPVGQ 333 PP PP P + Sbjct: 563 PPPPPPPPPPPLPGPAAE 580 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 23/99 (23%) Query: 236 PDLGQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVD 295 P +G +P P LP ++D + GP P P P P Sbjct: 516 PTMGAASSGPLPPPPPPLPP-SSDTPETVQNGPVTPPMPPPPPPPPPP------------ 562 Query: 296 LQDGVLTPPPPPPPPPPAPEVLAS---APPL-PPSTAAP 330 PPPPPPPPPP P A APPL PP +AP Sbjct: 563 ------PPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAP 595 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 48.5 bits (114), Expect = 1e-05 Identities = 41/129 (31%), Positives = 54/129 (41%), Gaps = 23/129 (17%) Query: 272 PSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPP--------PPPPPPPAPEVLASAPPL 323 P +P + P P F P L PPP PPPPPPP P PP Sbjct: 349 PPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP----PGPPP 404 Query: 324 PPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSV 383 PP T A GQ A S + P + S R+ LL +IRQ +LR V Sbjct: 405 PPFTGAD-GQPAIPPPLSDTTKPK-----SSLPAVSDARSDLLSAIRQG-----FQLRRV 453 Query: 384 KERKLEKKK 392 +E++ ++K+ Sbjct: 454 EEQREQEKR 462 Score = 40.8 bits (94), Expect = 0.003 Identities = 74/368 (20%), Positives = 118/368 (32%), Gaps = 74/368 (20%) Query: 40 LQKVSGDIFSRISQRVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPER 99 L K + DIF + + S+V ++ E+V Q K+ ++ ++ + + Sbjct: 43 LSKYAEDIFGELFTQANTFASRVSSLAERVDRLQVKVTQLDPKEEEVSL----------- 91 Query: 100 LQEYGSIFTGAQDPGLQRRPRHRIQS--KHRPLDERALQEK-LKDFPVCVSTKP-----E 151 G+ R R + + D +L L+ + C + P Sbjct: 92 -------------QGINTRKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLTP 138 Query: 152 PEDDAEEGLGGL--PSNISSVSSLLLFNTTENLYK------KYVFLDPLAGAVTKTHVML 203 DD +E L PS + + T+++ K K +P G V + Sbjct: 139 YRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKT 198 Query: 204 GAETEEKLFDAPLSISKREQLEQQ--VPENYFYVPDLGQVPEIDVPSYLP---------- 251 E EK+ + +E+L P + +G V +D SY P Sbjct: 199 RKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSP 258 Query: 252 -------DLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPP 304 +LP + Y D G + P + H A PL +PP Sbjct: 259 SPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLG--------SPP 310 Query: 305 -------PPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357 PPP PPPP P ++ PP PP G S P P Sbjct: 311 GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPP 370 Query: 358 PSGGRATL 365 P+ TL Sbjct: 371 PAADYPTL 378 >gi|55953110 retinoblastoma protein-binding zinc finger protein isoform c [Homo sapiens] Length = 1481 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%) Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298 GQ+P + +P+ P P ++ A P + P+ P P PL Sbjct: 758 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 816 Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353 L T P P P PP ++++A P PP+ ++ + SSS+S S Sbjct: 817 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 870 Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411 PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ + Sbjct: 871 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 927 Query: 412 LFNK 415 FNK Sbjct: 928 TFNK 931 >gi|20336260 retinoblastoma protein-binding zinc finger protein isoform b [Homo sapiens] Length = 1682 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%) Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298 GQ+P + +P+ P P ++ A P + P+ P P PL Sbjct: 959 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 1017 Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353 L T P P P PP ++++A P PP+ ++ + SSS+S S Sbjct: 1018 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 1071 Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411 PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ + Sbjct: 1072 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 1128 Query: 412 LFNK 415 FNK Sbjct: 1129 TFNK 1132 >gi|20336258 retinoblastoma protein-binding zinc finger protein isoform a [Homo sapiens] Length = 1718 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 17/184 (9%) Query: 239 GQVPEIDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQD 298 GQ+P + +P+ P P ++ A P + P+ P P PL Sbjct: 959 GQLPPLLIPTD-PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQ 1017 Query: 299 GVL-----TPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPR 353 L T P P P PP ++++A P PP+ ++ + SSS+S S Sbjct: 1018 SPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSS------ 1071 Query: 354 EVVDPSGGRATLLESIRQAGGIGKAKLR--SVKERKLEKKKQKEQEQVRATSQGGDLMSD 411 PS + + S+ +G +A L S K+ +LE + K +E+ ++ ++ ++ + Sbjct: 1072 ---SPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQE 1128 Query: 412 LFNK 415 FNK Sbjct: 1129 TFNK 1132 >gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 490 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/223 (27%), Positives = 84/223 (37%), Gaps = 13/223 (5%) Query: 139 LKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTK 198 L D P +S P P D +PS S V SLL + V P Sbjct: 146 LSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSP---PSDVPSPPSDVPSPP 202 Query: 199 THVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPE--IDVPSYLPDLPGI 256 + V L ++ D PL +S VP VP L VP DVPS L +P Sbjct: 203 SDVPLLSDVPSPPSDVPL-LSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSP 261 Query: 257 ANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPP--PPPPAP 314 +D+ +D+ P + P ++P+ + V P D+ + P PP P PP+ Sbjct: 262 PSDISPPSDV-PSLLSDVPSLPSDVPSLLSGVPSPPS-DVPSLLSDVPSPPSDVPSPPSD 319 Query: 315 EVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD 357 L S P PPS V S S P + G P + D Sbjct: 320 IPLLSGVPSPPS---DVPSPPSDVPSPPSDVPLLSGVPSPLSD 359 Score = 46.2 bits (108), Expect = 6e-05 Identities = 64/248 (25%), Positives = 88/248 (35%), Gaps = 34/248 (13%) Query: 119 PRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNT 178 P + + S HRPL L S P P D L G+PS S VSS + Sbjct: 95 PHYSLVSPHRPLVSPLL-----------SGVPSPPSDVPSLLSGVPSLPSDVSSPP--SD 141 Query: 179 TENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDL 238 +L L L+G + ++ D P S L VP VP Sbjct: 142 VPSLLSDVPSL--LSGVPSPP-----SDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPS- 193 Query: 239 GQVPEIDVPS------YLPDLPGIANDLMYSADLG--PGIAPSAPGTIPELPTFHTEVAE 290 P DVPS L D+P +D+ +D+ P PS P +P L + ++ Sbjct: 194 ---PPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSD 250 Query: 291 PLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQG 350 L GV +PP PP P +L+ P LP + + S V Sbjct: 251 V--PSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPS 308 Query: 351 APREVVDP 358 P +V P Sbjct: 309 PPSDVPSP 316 Score = 29.3 bits (64), Expect = 7.9 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 20/74 (27%) Query: 244 IDVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTP 303 +DVPS L D+P + + + PS+P +P LP+ V + GV + Sbjct: 396 LDVPSLLSDVPSLLSGV-----------PSSPSGVPSLPS---------GVPILSGVPSL 435 Query: 304 PPPPPPPPPAPEVL 317 P P P P L Sbjct: 436 PSGVPSPSGVPITL 449 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 13/111 (11%) Query: 264 ADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPL 323 A L P P+APGT+ + P F A P P P PP PAP A+APP Sbjct: 223 AALLPLPKPAAPGTVIQTPPFVGAAAPP----------APAAPSPPAAPAPAAPAAAPPP 272 Query: 324 PPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGG 374 PP A + + +A+P+V P +GG A + A G Sbjct: 273 PPPAPATLARPPGHPAGPPTAAPAV---PPPAAAQNGGSAGAAPAPAPAAG 320 Score = 38.1 bits (87), Expect = 0.017 Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 43/124 (34%) Query: 267 GPGIAP-----------------------------------SAPGTIPELPTFHTEVAEP 291 GPG A +APGT+ + P F A P Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250 Query: 292 LKV----DLQDGVLTPPPPPPPPPPAPEVLASAP--PLPPSTAAPV--GQGARQDDSSSS 343 P PPPPPPAP LA P P P TAAP A Q+ S+ Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310 Query: 344 ASPS 347 A+P+ Sbjct: 311 AAPA 314 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/48 (50%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 302 TPPPPPPPPPPAPEVLASAPPLPPST-AAPVGQGARQDDSSSSASPSV 348 TP PPPPPPPP P L +APP P ST A P + + A PSV Sbjct: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSV 2083 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 8/54 (14%) Query: 285 HTEVAEPLKVDLQDGVLTPPPPPPPPPPA--------PEVLASAPPLPPSTAAP 330 H + PL+ + PPPPPPPP PA P + ASAPP+ T AP Sbjct: 2025 HYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAP 2078 Score = 30.8 bits (68), Expect = 2.7 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 236 PDLGQVPEIDVPSYLPDLP--GIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLK 293 P+L +P VPS P LP G+ N ++ P A + P+ P + + + Sbjct: 3149 PNLMGLPSTTVPS--PGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQ 3206 Query: 294 VDLQDGVLTPPPPPPPPPPAPEV 316 V PPPP PPP P++ Sbjct: 3207 VQQP-----PPPPAAQPPPTPQL 3224 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 47.4 bits (111), Expect = 3e-05 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 268 PGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVL-ASAPPLPPS 326 P + P AP P LP T PL V PP P PPPPPA E S PP+ P+ Sbjct: 404 PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPA 463 Query: 327 TAA------PVGQGARQDDSSSSASP------------SVQGAPREVVDPSGGRATLLES 368 T + P+ R + ++ A P + G P + + T L++ Sbjct: 464 TCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKN 523 Query: 369 IRQ 371 IRQ Sbjct: 524 IRQ 526 Score = 46.2 bits (108), Expect = 6e-05 Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 2/112 (1%) Query: 272 PSAPGTI-PELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAP 330 P P TI P PT T PL L + P PPPPPPP VL+S P PP A Sbjct: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIR 2277 Query: 331 VGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRS 382 V + + S A P + APR D T +GG + ++++ Sbjct: 2278 VKRVSTFSGRSPPAPPPYK-APRLDEDGEASEDTPQVPGLGSGGFSRVRMKT 2328 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Query: 268 PGIAPSAPGTIPELPTFHTEVA-EP-LKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPP 325 P AP+ P T LP + EP + L PPPP PPPPPAP S PP P Sbjct: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP----SPPPAPA 638 Query: 326 STA 328 +++ Sbjct: 639 TSS 641 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/74 (32%), Positives = 29/74 (39%) Query: 289 AEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSV 348 AE + L LTPP P PPPP P + PPL P PV A Sbjct: 394 AEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQ 453 Query: 349 QGAPREVVDPSGGR 362 + +P VV + R Sbjct: 454 EESPPPVVPATCSR 467 Score = 34.3 bits (77), Expect = 0.25 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 14/70 (20%) Query: 272 PSAPGTIPELPTFHTEVAEPLKV-DLQDGVLTPP-----------PPPPPPPPAPEVLAS 319 P P +P P T + P+ + + + +L P PPPPP PP P A Sbjct: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP--AP 631 Query: 320 APPLPPSTAA 329 +PP P+T++ Sbjct: 632 SPPPAPATSS 641 Score = 33.5 bits (75), Expect = 0.42 Identities = 17/51 (33%), Positives = 23/51 (45%) Query: 281 LPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPV 331 +P E A+ L +PPPP PPP +P PP PP + P+ Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441 Score = 32.7 bits (73), Expect = 0.72 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 290 EPLKVDLQDGVLTPP---PPPPPPPPAPEVLASAPPLPPSTAAPVGQGAR 336 +P KV++ VL PP PP P PAP P PPST P+ + R Sbjct: 553 KPPKVEVSP-VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR 601 Score = 32.7 bits (73), Expect = 0.72 Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 67/237 (28%) Query: 272 PSAPGTIPELPTF-----HTEVAEPLKVDLQDGVLTPPP------PPPPPPPAPEVLASA 320 P AP T P T LK+ + VLTPPP P P PPPA + A Sbjct: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKI--YESVLTPPPLGAPEAPEPEPPPADDSPAEP 691 Query: 321 PP--------LPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVD--------------- 357 P L APV + + S +P++ P+ Sbjct: 692 EPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQ 751 Query: 358 ------------PSGGRATLLESIRQAGGIGKAKLRSVKER----------KLEKKKQKE 395 PS + LE R A G+G L V+E+ +L K Q++ Sbjct: 752 ALPPPQPQLQPPPSPQQMPPLEKARIA-GVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQ 810 Query: 396 QEQVRAT---SQGGDLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPLP 449 Q++V A+ S GG + ++ K IS +GP E R S P P Sbjct: 811 QQKVAASMPLSPGGQM-----EEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESP 862 Score = 32.3 bits (72), Expect = 0.94 Identities = 59/240 (24%), Positives = 85/240 (35%), Gaps = 45/240 (18%) Query: 248 SYLPDLPGIANDLMYSADLGPGIAPSAPGT-----IPELPTFHTEVAEPLKVDLQDGVLT 302 ++LP PG+ LGP P P T + +L ++A G Sbjct: 2164 AWLPGAPGVR-----VLSLGPAPEPPKPATSKIILVNKLGQVFVKMA---------GEGE 2209 Query: 303 PPPPPPPPPPAPEVLASAPPLPPSTAAPVGQ--GARQDDSSSSASPSVQGAPREVVDPSG 360 P PPP PP P + +P P S P G G +P P +V SG Sbjct: 2210 PVPPPVKQPPLPPTI--SPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSG 2267 Query: 361 GRATLLESIR-----QAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNK 415 + ++IR G K +L++ + ++ T Q L S F++ Sbjct: 2268 PASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASED----TPQVPGLGSGGFSR 2323 Query: 416 LVMRRKGISG------KGPGAGEGPGGAFARVSDSIPPLP---PPQQPQAEED---EDDW 463 + M+ + G G AGE G S + PLP PPQ P D E W Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLL-PLPEDGPPQVPDGPPDLLLESQW 2382 Score = 32.0 bits (71), Expect = 1.2 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 270 IAPSAPGTIPELPTFHTEVAEPLKV---DLQDGVLTPPPPPPPPPPAPEVLASAPPLPPS 326 ++P + P ++ +PL+ L L PP P PPP+P+ + PPL + Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM---PPLEKA 775 Query: 327 TAAPVG 332 A VG Sbjct: 776 RIAGVG 781 Score = 30.8 bits (68), Expect = 2.7 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 23/74 (31%) Query: 272 PSAPGTIPEL-------PTFH-TEVAEPLKVDLQDGVLTPPPPPPP---PPPAP------ 314 PS P +PE PTF T + L P PPPPP PPPAP Sbjct: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPATSSRR 643 Query: 315 EVLASAPPLPPSTA 328 +L AP PS A Sbjct: 644 PLLLRAPQFTPSEA 657 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 46.2 bits (108), Expect = 6e-05 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 270 IAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTA- 328 ++P+ P P LP+ + L+ + TPPPP PPPPP P AP +PP A Sbjct: 320 VSPTPPPPPPPLPSALS--TSSLRASMTS---TPPPPVPPPPPPPATALQAPAVPPPPAP 374 Query: 329 APVGQGARQDDSSSSASPSVQGAP 352 + G A P VQ +P Sbjct: 375 LQIAPGVLHPAPPPIAPPLVQPSP 398 Score = 45.8 bits (107), Expect = 8e-05 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 24/171 (14%) Query: 247 PSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPP 306 P+ L PG+ + + P + +P P T PL G+ PPPP Sbjct: 372 PAPLQIAPGVLHPA--PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429 Query: 307 PPPPPPA---------------PEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGA 351 PP PPP P L P P P+ + ++ P + Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489 Query: 352 PREVVDPSGGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRAT 402 V+ S R+ LLE+IR+ +LR V+E++ ++ K + E AT Sbjct: 490 TLPVI--SDARSVLLEAIRKG-----IQLRKVEEQREQEAKHERIENDVAT 533 Score = 35.8 bits (81), Expect = 0.085 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 11/42 (26%) Query: 300 VLTPPPPPPPPPPAPEVLASA-----------PPLPPSTAAP 330 V P PPPPPPP P L+++ PP+PP P Sbjct: 318 VFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPP 359 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.132 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,894,738 Number of Sequences: 37866 Number of extensions: 1487443 Number of successful extensions: 35631 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 765 Number of HSP's successfully gapped in prelim test: 899 Number of HSP's that attempted gapping in prelim test: 14390 Number of HSP's gapped (non-prelim): 10515 length of query: 465 length of database: 18,247,518 effective HSP length: 106 effective length of query: 359 effective length of database: 14,233,722 effective search space: 5109906198 effective search space used: 5109906198 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.