BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|166235186 APAF1 interacting protein [Homo sapiens] (242 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|166235186 APAF1 interacting protein [Homo sapiens] 513 e-146 gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens] 36 0.026 gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens] 36 0.026 gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens] 36 0.026 gi|38570135 mitogen-activated protein kinase kinase kinase kinas... 30 2.5 gi|14589909 mitogen-activated protein kinase kinase kinase kinas... 30 2.5 gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 29 3.2 gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d... 28 5.5 gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c... 28 5.5 gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a... 28 5.5 gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [... 28 5.5 gi|4759166 secreted phosphoprotein 1 isoform b [Homo sapiens] 28 9.4 gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens] 28 9.4 gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens] 28 9.4 gi|9257190 adducin 2 isoform e [Homo sapiens] 28 9.4 gi|89276787 adducin 2 isoform b [Homo sapiens] 28 9.4 gi|9257192 adducin 2 isoform a [Homo sapiens] 28 9.4 >gi|166235186 APAF1 interacting protein [Homo sapiens] Length = 242 Score = 513 bits (1321), Expect = e-146 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MSGCDAREGDCCSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAP 60 MSGCDAREGDCCSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAP Sbjct: 1 MSGCDAREGDCCSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAP 60 Query: 61 SGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKA 120 SGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKA Sbjct: 61 SGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKA 120 Query: 121 AVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHA 180 AVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHA Sbjct: 121 AVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHA 180 Query: 181 MNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENG 240 MNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENG Sbjct: 181 MNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENG 240 Query: 241 IV 242 IV Sbjct: 241 IV 242 >gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens] Length = 674 Score = 36.2 bits (82), Expect = 0.026 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 28/189 (14%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW IS+ K D I I P G+ ++ +I + + S + K+ + Sbjct: 152 GWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHT 211 Query: 96 QCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRY 155 +P T VIH H+ A + + G I+ + ++ G YY Y Sbjct: 212 GFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGI-LPISQESLLLG-----DVAYYDY 265 Query: 156 DDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEKAKTMCECY 214 L EE++ + ++ + SC VLV R HGV GET E E + Sbjct: 266 QGSL---------EEQEERIQLQKVLGP---SCKVLVLRNHGVVALGETLE------EAF 307 Query: 215 DYLFDIAVS 223 Y+F++ ++ Sbjct: 308 HYIFNVQLA 316 >gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens] Length = 674 Score = 36.2 bits (82), Expect = 0.026 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 28/189 (14%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW IS+ K D I I P G+ ++ +I + + S + K+ + Sbjct: 152 GWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHT 211 Query: 96 QCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRY 155 +P T VIH H+ A + + G I+ + ++ G YY Y Sbjct: 212 GFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGI-LPISQESLLLG-----DVAYYDY 265 Query: 156 DDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEKAKTMCECY 214 L EE++ + ++ + SC VLV R HGV GET E E + Sbjct: 266 QGSL---------EEQEERIQLQKVLGP---SCKVLVLRNHGVVALGETLE------EAF 307 Query: 215 DYLFDIAVS 223 Y+F++ ++ Sbjct: 308 HYIFNVQLA 316 >gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens] Length = 706 Score = 36.2 bits (82), Expect = 0.026 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 28/189 (14%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW IS+ K D I I P G+ ++ +I + + S + K+ + Sbjct: 152 GWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHT 211 Query: 96 QCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRY 155 +P T VIH H+ A + + G I+ + ++ G YY Y Sbjct: 212 GFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGI-LPISQESLLLG-----DVAYYDY 265 Query: 156 DDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEKAKTMCECY 214 L EE++ + ++ + SC VLV R HGV GET E E + Sbjct: 266 QGSL---------EEQEERIQLQKVLGP---SCKVLVLRNHGVVALGETLE------EAF 307 Query: 215 DYLFDIAVS 223 Y+F++ ++ Sbjct: 308 HYIFNVQLA 316 >gi|38570135 mitogen-activated protein kinase kinase kinase kinase 5 [Homo sapiens] Length = 846 Score = 29.6 bits (65), Expect = 2.5 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 114 IHTHSKAAVMATLLFPGREFKITHQE--MIKGIKKCTSGGYY 153 +HT AAV L PG +F + QE M+K K C Y+ Sbjct: 40 VHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYF 81 >gi|14589909 mitogen-activated protein kinase kinase kinase kinase 5 [Homo sapiens] Length = 846 Score = 29.6 bits (65), Expect = 2.5 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 114 IHTHSKAAVMATLLFPGREFKITHQE--MIKGIKKCTSGGYY 153 +HT AAV L PG +F + QE M+K K C Y+ Sbjct: 40 VHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYF 81 >gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapiens] Length = 1771 Score = 29.3 bits (64), Expect = 3.2 Identities = 18/62 (29%), Positives = 27/62 (43%) Query: 50 LKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRG 109 +K GD I + SGV P D + + D SG K S+ + LF ++G Sbjct: 1452 MKRGDVIDYSSSGVSTNDASPLDPITEEDEKSDQSGSKLLPGKKSSERSSLFQTDLKLKG 1511 Query: 110 AG 111 +G Sbjct: 1512 SG 1513 >gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d [Homo sapiens] Length = 521 Score = 28.5 bits (62), Expect = 5.5 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 8/51 (15%) Query: 45 GGGISLKHGDEIYIAPSG--------VQKERIQPEDMFVCDINEKDISGPS 87 G GIS GD + I PS Q + P+ +F+ E D+S P+ Sbjct: 203 GSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPT 253 >gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c [Homo sapiens] Length = 590 Score = 28.5 bits (62), Expect = 5.5 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 8/51 (15%) Query: 45 GGGISLKHGDEIYIAPSG--------VQKERIQPEDMFVCDINEKDISGPS 87 G GIS GD + I PS Q + P+ +F+ E D+S P+ Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPT 287 >gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a [Homo sapiens] Length = 606 Score = 28.5 bits (62), Expect = 5.5 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 8/51 (15%) Query: 45 GGGISLKHGDEIYIAPSG--------VQKERIQPEDMFVCDINEKDISGPS 87 G GIS GD + I PS Q + P+ +F+ E D+S P+ Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPT 287 >gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [Homo sapiens] Length = 597 Score = 28.5 bits (62), Expect = 5.5 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 8/51 (15%) Query: 45 GGGISLKHGDEIYIAPSG--------VQKERIQPEDMFVCDINEKDISGPS 87 G GIS GD + I PS Q + P+ +F+ E D+S P+ Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPT 287 >gi|4759166 secreted phosphoprotein 1 isoform b [Homo sapiens] Length = 300 Score = 27.7 bits (60), Expect = 9.4 Identities = 16/48 (33%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Query: 135 ITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMN 182 I QE+ K ++ S ++ ++DMLVV ++ E+K LK R++H ++ Sbjct: 247 IDSQELSKVSREFHSHEFHSHEDMLVVD-PKSKEEDKHLKFRISHELD 293 >gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens] Length = 287 Score = 27.7 bits (60), Expect = 9.4 Identities = 16/48 (33%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Query: 135 ITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMN 182 I QE+ K ++ S ++ ++DMLVV ++ E+K LK R++H ++ Sbjct: 234 IDSQELSKVSREFHSHEFHSHEDMLVVD-PKSKEEDKHLKFRISHELD 280 >gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens] Length = 314 Score = 27.7 bits (60), Expect = 9.4 Identities = 16/48 (33%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Query: 135 ITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMN 182 I QE+ K ++ S ++ ++DMLVV ++ E+K LK R++H ++ Sbjct: 261 IDSQELSKVSREFHSHEFHSHEDMLVVD-PKSKEEDKHLKFRISHELD 307 >gi|9257190 adducin 2 isoform e [Homo sapiens] Length = 643 Score = 27.7 bits (60), Expect = 9.4 Identities = 37/181 (20%), Positives = 68/181 (37%), Gaps = 38/181 (20%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW + ++L K D I+P GV + + +I + + K S Sbjct: 148 GWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE--------KGS 199 Query: 96 QCTPLFMNAYTMRGA--------GAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKC 147 C P+ + + A +IH H+ A + + G ++H ++ G Sbjct: 200 SCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGL-LPVSHNALLVG---- 254 Query: 148 TSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEK 206 YY ++ + E + +L+ + +C +LV R HGV G+T E+ Sbjct: 255 -DMAYYDFNGEM-----EQEADRINLQKCLG-------PTCKILVLRNHGVVALGDTVEE 301 Query: 207 A 207 A Sbjct: 302 A 302 >gi|89276787 adducin 2 isoform b [Homo sapiens] Length = 559 Score = 27.7 bits (60), Expect = 9.4 Identities = 37/181 (20%), Positives = 68/181 (37%), Gaps = 38/181 (20%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW + ++L K D I+P GV + + +I + + K S Sbjct: 148 GWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE--------KGS 199 Query: 96 QCTPLFMNAYTMRGA--------GAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKC 147 C P+ + + A +IH H+ A + + G ++H ++ G Sbjct: 200 SCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGL-LPVSHNALLVG---- 254 Query: 148 TSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEK 206 YY ++ + E + +L+ + +C +LV R HGV G+T E+ Sbjct: 255 -DMAYYDFNGEM-----EQEADRINLQKCLG-------PTCKILVLRNHGVVALGDTVEE 301 Query: 207 A 207 A Sbjct: 302 A 302 >gi|9257192 adducin 2 isoform a [Homo sapiens] Length = 726 Score = 27.7 bits (60), Expect = 9.4 Identities = 37/181 (20%), Positives = 68/181 (37%), Gaps = 38/181 (20%) Query: 39 GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95 GW + ++L K D I+P GV + + +I + + K S Sbjct: 148 GWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE--------KGS 199 Query: 96 QCTPLFMNAYTMRGA--------GAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKC 147 C P+ + + A +IH H+ A + + G ++H ++ G Sbjct: 200 SCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGL-LPVSHNALLVG---- 254 Query: 148 TSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEK 206 YY ++ + E + +L+ + +C +LV R HGV G+T E+ Sbjct: 255 -DMAYYDFNGEM-----EQEADRINLQKCLG-------PTCKILVLRNHGVVALGDTVEE 301 Query: 207 A 207 A Sbjct: 302 A 302 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,796,325 Number of Sequences: 37866 Number of extensions: 500095 Number of successful extensions: 896 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 2 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 893 Number of HSP's gapped (non-prelim): 18 length of query: 242 length of database: 18,247,518 effective HSP length: 99 effective length of query: 143 effective length of database: 14,498,784 effective search space: 2073326112 effective search space used: 2073326112 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.