Search of human proteins with 16418361

Search of human proteins with 16418361

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16418361 RFT1 homolog [Homo sapiens]
         (541 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16418361 RFT1 homolog [Homo sapiens]                              1068   0.0  
gi|134152694 guanylate cyclase 2F [Homo sapiens]                       32   1.1  
gi|32171233 BCDIN3 domain containing [Homo sapiens]                    32   1.5  
gi|22907060 solute carrier family 47, member 1 [Homo sapiens]          32   1.9  
gi|134244587 endothelial differentiation, sphingolipid G-protein...    30   4.3  
gi|218749848 family with sequence similarity 38, member A [Homo ...    30   7.3  
gi|50083289 selenoprotein I [Homo sapiens]                             30   7.3  

>gi|16418361 RFT1 homolog [Homo sapiens]
          Length = 541

 Score = 1068 bits (2763), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLF 60
           MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLF
Sbjct: 1   MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLF 60

Query: 61  LAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYA 120
           LAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYA
Sbjct: 61  LAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYA 120

Query: 121 TGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLY 180
           TGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLY
Sbjct: 121 TGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLY 180

Query: 181 IFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEA 240
           IFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEA
Sbjct: 181 IFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEA 240

Query: 241 KLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESF 300
           KLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESF
Sbjct: 241 KLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESF 300

Query: 301 YIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGG 360
           YIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGG
Sbjct: 301 YIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGG 360

Query: 361 TMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSY 420
           TMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSY
Sbjct: 361 TMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSY 420

Query: 421 LLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGG 480
           LLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGG
Sbjct: 421 LLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGG 480

Query: 481 VTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKM 540
           VTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKM
Sbjct: 481 VTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKM 540

Query: 541 T 541
           T
Sbjct: 541 T 541


>gi|134152694 guanylate cyclase 2F [Homo sapiens]
          Length = 1108

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 22/176 (12%)

Query: 307 VLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLAL-DIYGGTMLSS 365
           + ER ++  ++KQ+   +   +L   +  +L  G T+   GF    L   DI G T +S+
Sbjct: 839 IRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISA 898

Query: 366 GSGPVLLRSYC--LYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLT 423
            S P+ +      LY L  AI G  + +                   +  +++V S L  
Sbjct: 899 MSEPIEVVDLLNDLYTLFDAIIGSHDVYKVET---------------IGDAYMVASGLPK 943

Query: 424 RWCGSVGFILANCFNMGIRITQSL-CFIHRYYRRSPHRPLAGLHLSPVLLGTFALS 478
           R   +     A   NM + I  S+  F  R+    P R   GLH  PV+ G   L+
Sbjct: 944 R---NGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLT 996


>gi|32171233 BCDIN3 domain containing [Homo sapiens]
          Length = 292

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 18/62 (29%), Positives = 31/62 (50%)

Query: 234 FINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIF 293
           F+N +  K+  S F   F + +   G    +T    LN GD G+++ + +L SL   L+ 
Sbjct: 136 FMNQRTRKVLLSSFLSQFGRSVFDIGFCMSITMWIHLNHGDHGLWEFLAHLSSLCHYLLV 195

Query: 294 QP 295
           +P
Sbjct: 196 EP 197


>gi|22907060 solute carrier family 47, member 1 [Homo sapiens]
          Length = 570

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 18/205 (8%)

Query: 13  LASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLS 72
           LA    L+Q++  LI+F+ + F    L K  +  V + + ++  T + +       AC +
Sbjct: 41  LAGPAFLVQLMVFLISFISSVFC-GHLGKLELDAVTLAIAVINVTGVSVGF-GLSSACDT 98

Query: 73  GGTQRDWSQTLNLLWLTVPLGVF---------WSLFLGWIWLQLLEVPDPNVVPHYATGV 123
             +Q   SQ L  + + +              W+LFL    + LL   DP+V     T V
Sbjct: 99  LISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYV 158

Query: 124 VLF--GLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYI 181
            +F   L A    + +  ++L Q    + L  I   ++  L + L  +L L   H G+  
Sbjct: 159 TIFIPALPATFLYMLQVKYLLNQG---IVLPQIVTGVAANLVNALANYLFLHQLHLGVIG 215

Query: 182 FSLAQLF--YTTVLVLCYVIYFTKL 204
            +LA L   YT  L+L   I   KL
Sbjct: 216 SALANLISQYTLALLLFLYILGKKL 240


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 32/207 (15%)

Query: 13  LASSGLLLQVLFRLITFVLNAFILRFLSKE-IVGVVNVRLTLLYSTTLFLAREAFRRACL 71
           LA+S LL  V F   T +  +  LR    +      +  +TL  S    LA    R   +
Sbjct: 75  LAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAI 134

Query: 72  SGGTQRDWSQTLNLLWLTVPLGVFWSL--------FLGWIWLQLLEVPDPNVVPHYATGV 123
           +        ++  +L L   +G  W +         LGW  L  LE     V+P YA   
Sbjct: 135 AKVKLYGSDKSCRMLLL---IGASWLISLVLGGLPILGWNCLGHLEACS-TVLPLYAKHY 190

Query: 124 VL-------FGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSV---LTAFLVLW 173
           VL         L A+V L    + V+  +H      + A     +LK+V   L  F+V W
Sbjct: 191 VLCVVTIFSIILLAIVALYVRIYCVVRSSHA----DMAAPQTLALLKTVTIVLGVFIVCW 246

Query: 174 LPHWGLYIFSLAQLFYTTVLVLCYVIY 200
           LP      FS+  L Y   +  C ++Y
Sbjct: 247 LP-----AFSILLLDYACPVHSCPILY 268


>gi|218749848 family with sequence similarity 38, member A [Homo
           sapiens]
          Length = 2090

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 21/131 (16%)

Query: 117 PHYAT----GVVLFGLSA--VVELLGEPFWVLAQAHMFVK-------LKVIA-ESLSVIL 162
           PH AT    G   +GL A  ++EL      VL++  +F++        K++A  ++ V L
Sbjct: 337 PHQATQVPEGAAKWGLVAERLLELAAGFSDVLSRVQVFLRRLLELHVFKLVALYTVWVAL 396

Query: 163 KSVLTAFL---VLW---LPHWGLY-IFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQT 215
           K V    L   VLW   LP+     + S     +T V+++C ++Y  K++   E +   T
Sbjct: 397 KEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCT 456

Query: 216 LPVSRITDLLP 226
            P    T+LLP
Sbjct: 457 EPFPNSTNLLP 467


>gi|50083289 selenoprotein I [Homo sapiens]
          Length = 397

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 51/233 (21%), Positives = 103/233 (44%), Gaps = 29/233 (12%)

Query: 15  SSGLLLQVLFRLITFVLNAFILRFLSKEIVGVV---------NVRLTLLYSTTLFLAREA 65
           S+G+ + VL+ L+  VL +FIL    K   G++          V ++ +Y  T  +  EA
Sbjct: 148 STGVSVFVLYLLLWVVLFSFILSHWEKYNTGILFLPWGYDISQVTISFVYIVTAVVGVEA 207

Query: 66  FRRACLSGGTQRDWSQTLNL---LWLTVPLGVF--------WSLFLGWIWLQLLEVPDPN 114
           +    L     RD    + +   L +T+P+ +          +L L  ++  ++ +  P 
Sbjct: 208 WYEPFLFNFLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKNNTLKLNSVYEAMVPLFSPC 267

Query: 115 VVPHYATGVVLFGLSAVVELLGEPFWVL---AQAHMFVKLKVIAESLS---VILKSVLTA 168
           ++   +T  +L+  S ++EL    F+ +   A A+   +L V   S +    +   ++  
Sbjct: 268 LLFILSTAWILWSPSDILELHPRVFYFMVGTAFANSTCQLIVCQMSSTRCPTLNWLLVPL 327

Query: 169 FLVLWLPHWGL--YIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVS 219
           FLV+ + + G+  Y+ S+     TT   L ++ Y  +++    S+  Q  P S
Sbjct: 328 FLVVLVVNLGVASYVESILLYTLTTAFTLAHIHYGVRVV-KQLSSHFQIYPFS 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.141    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,701,087
Number of Sequences: 37866
Number of extensions: 723064
Number of successful extensions: 2054
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2050
Number of HSP's gapped (non-prelim): 9
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.