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Search of human proteins with 163659920
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163659920 pannexin 2 isoform 1 [Homo sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163659920 pannexin 2 isoform 1 [Homo sapiens] 1361 0.0
gi|237757297 pannexin 2 isoform 2 [Homo sapiens] 1271 0.0
gi|16418453 pannexin 3 [Homo sapiens] 144 3e-34
gi|39995064 pannexin 1 [Homo sapiens] 127 3e-29
gi|110832843 TBP-associated factor 4 [Homo sapiens] 54 6e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 53 1e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 2e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 2e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 49 2e-05
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 48 3e-05
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 48 3e-05
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 47 8e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens] 46 1e-04
gi|221139926 NHS-like 1 [Homo sapiens] 45 2e-04
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 45 2e-04
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 45 3e-04
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 45 3e-04
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 44 4e-04
gi|60460889 Myb protein P42POP [Homo sapiens] 44 5e-04
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 44 6e-04
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 44 6e-04
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 44 6e-04
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 44 6e-04
gi|122937321 UNC homeobox [Homo sapiens] 43 8e-04
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 43 0.001
gi|163965366 nascent polypeptide-associated complex alpha subuni... 43 0.001
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 43 0.001
gi|33186895 selenoprotein V [Homo sapiens] 42 0.001
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 42 0.002
gi|39812378 RAN binding protein 9 [Homo sapiens] 42 0.002
>gi|163659920 pannexin 2 isoform 1 [Homo sapiens]
Length = 677
Score = 1361 bits (3523), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL 60
MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL
Sbjct: 1 MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL 60
Query: 61 VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE 120
VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE
Sbjct: 61 VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE 120
Query: 121 HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI 180
HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI
Sbjct: 121 HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI 180
Query: 181 QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV 240
QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV
Sbjct: 181 QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV 240
Query: 241 PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV 300
PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV
Sbjct: 241 PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV 300
Query: 301 MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS 360
MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS
Sbjct: 301 MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS 360
Query: 361 LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP 420
LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP
Sbjct: 361 LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP 420
Query: 421 PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS 480
PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS
Sbjct: 421 PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS 480
Query: 481 AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR 540
AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR
Sbjct: 481 AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR 540
Query: 541 SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV 600
SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV
Sbjct: 541 SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV 600
Query: 601 APLTPASLGKAEPLTILSRNATHPLLHINTLYEAREEEDGGPRLPQDVGDLIAIPAPQQI 660
APLTPASLGKAEPLTILSRNATHPLLHINTLYEAREEEDGGPRLPQDVGDLIAIPAPQQI
Sbjct: 601 APLTPASLGKAEPLTILSRNATHPLLHINTLYEAREEEDGGPRLPQDVGDLIAIPAPQQI 660
Query: 661 LIATFDEPRTVVSTVEF 677
LIATFDEPRTVVSTVEF
Sbjct: 661 LIATFDEPRTVVSTVEF 677
>gi|237757297 pannexin 2 isoform 2 [Homo sapiens]
Length = 643
Score = 1271 bits (3288), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL 60
MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL
Sbjct: 1 MHHLLEQSADMATALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVL 60
Query: 61 VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE 120
VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE
Sbjct: 61 VPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFE 120
Query: 121 HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI 180
HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI
Sbjct: 121 HKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQI 180
Query: 181 QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV 240
QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV
Sbjct: 181 QSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAV 240
Query: 241 PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV 300
PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV
Sbjct: 241 PISYLCTYYATQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCV 300
Query: 301 MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS 360
MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS
Sbjct: 301 MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKS 360
Query: 361 LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP 420
LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP
Sbjct: 361 LNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEP 420
Query: 421 PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS 480
PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS
Sbjct: 421 PVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS 480
Query: 481 AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR 540
AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR
Sbjct: 481 AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR 540
Query: 541 SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV 600
SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV
Sbjct: 541 SQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV 600
Query: 601 APLTPASLGKAEPLTILSRNATHPLLHINTL 631
APLTPASLGKAEPLTILSRNATHPLLHINTL
Sbjct: 601 APLTPASLGKAEPLTILSRNATHPLLHINTL 631
>gi|16418453 pannexin 3 [Homo sapiens]
Length = 392
Score = 144 bits (363), Expect = 3e-34
Identities = 101/332 (30%), Positives = 173/332 (52%), Gaps = 18/332 (5%)
Query: 44 LKLELPFDRVVTIGTVLVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTE 102
L+LELP DR+V V P+LL++L F + F+ PI C++P NF+ QA Y CW
Sbjct: 28 LRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDS 87
Query: 103 L---RDALPGVDA--SLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFL 157
L + PG D SLWP HK LPY+LLA A +MY+P L W++ A L+S+L F+
Sbjct: 88 LLHHKQDGPGQDKMKSLWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFI 143
Query: 158 LQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERR 217
+ E+D Y+R+ ++ + +S P + E +E A KE+ E L E+YL +
Sbjct: 144 ISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACK 199
Query: 218 GRSNFLAKLYLARHVLILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVR 276
RS+ L YL R+ L+L+ ++ YL ++ Q EF+C++ P +
Sbjct: 200 QRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL- 258
Query: 277 VSCKLPSVQLQRIIAGVDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQ 335
++C+L S+ + +I++ + + ++ +I+ NL L + K +++ L + +R+
Sbjct: 259 ITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKM 318
Query: 336 WRRSQFCDINILAMFCNENRDHIKSLNRLDFI 367
D+N++ +F N + S + L +
Sbjct: 319 -LGCPINDLNVILLFLRANISELISFSWLSVL 349
>gi|39995064 pannexin 1 [Homo sapiens]
Length = 426
Score = 127 bits (320), Expect = 3e-29
Identities = 90/336 (26%), Positives = 174/336 (51%), Gaps = 20/336 (5%)
Query: 44 LKLELPFDRVVTIGTVLVPILLVTLVFTKNFA-EEPIYCYTPHNFTRDQALYARGYCWTE 102
L+LEL D++VT V +P+LL++L F + + I C++P +F+ QA + YCW
Sbjct: 28 LRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAA 87
Query: 103 L--RDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQE 160
+ +++L +L L+ HKF PY LL FA ++Y+P L W F A+ + S+L F+++E
Sbjct: 88 VQQKNSLQSESGNL--PLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEE 145
Query: 161 IDNCYHRAAEGRAPKIEKQIQSKG-----PGITEREKREIIENAEKE-KSPEQNLFEKYL 214
+D Y+RA +A K + + + PG+TE + + E +E K P + E+YL
Sbjct: 146 LDKVYNRAI--KAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYP---IVEQYL 200
Query: 215 ERRGRSNFLAKLYLARHVLILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGP 273
+ + SN L Y++ +L L++ + YL Y++ + +EF C++ + P
Sbjct: 201 KTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVP 260
Query: 274 AVRVSCKLPSVQLQRIIAGVDIVLLCVMNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTR 333
+ CKL +V + ++++ +++V+ ++ +++ L FR+ + +
Sbjct: 261 D-QFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTL--FVPFRQKTDVLKVYEILPTFDV 317
Query: 334 RQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITN 369
++ + D+++ +F EN +KS L + N
Sbjct: 318 LHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLEN 353
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 53.5 bits (127), Expect = 6e-07
Identities = 70/241 (29%), Positives = 84/241 (34%), Gaps = 34/241 (14%)
Query: 393 ATPTVRDSGVQTVDPSANPAEPDGAAE----PPVVKRPRKKMKWIPTS---NPLPQPFKE 445
A P G P A A P G PP +RP P + P P+
Sbjct: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135
Query: 446 PLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAP 505
A + + A P+PA A A L R+ PGPGP P P P P P
Sbjct: 136 SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG---------PGPGPGPGPGPGPGP 186
Query: 506 DKK--HARHFSLDVHPYILGTKKAKAEAV------PAAL--------PASRSQEGGFLSQ 549
K +L+ +L + A A AV PAAL P + Q F+
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246
Query: 550 AEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPP-AAPAVAPLTPASL 608
A P AP P P PA A L + P H PP AAPAV P A
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATL-ARPPGHPAGPPTAAPAVPPPAAAQN 305
Query: 609 G 609
G
Sbjct: 306 G 306
Score = 43.9 bits (102), Expect = 5e-04
Identities = 71/259 (27%), Positives = 88/259 (33%), Gaps = 52/259 (20%)
Query: 384 AALAQSNHDATPTVR--DSGVQTVDPSANPAEPD---------GAAEPPVVKRPRKKMKW 432
AAL S+H A P V ++G + P PA P GAA PP P
Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP 261
Query: 433 IPTSNPL--PQPFKEPLAIMRVENSKAEKPK-------PARRKTATDTLIAPLLDRSAHH 483
P + P P P + R A P PA + AP +A
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321
Query: 484 YKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRS-Q 542
G G PGPG A A PAP K ++ V AA PA+++
Sbjct: 322 PAGVSGQPGPG---AAAAAPAPGVK----------------AESPKRVVQAAPPAAQTLA 362
Query: 543 EGGFLSQAEDCGLGLAPAPIKDAPLPE-KEIPYPTEPARAGLPSGGPFHV-----RSPPA 596
G S A +G P LP +P P GLP G V R+P A
Sbjct: 363 ASGPASTAASMVIG----PTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTA 418
Query: 597 APA--VAPLTPASLGKAEP 613
+ A LTP L P
Sbjct: 419 TTSGIRATLTPTVLAPRLP 437
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/234 (26%), Positives = 77/234 (32%), Gaps = 40/234 (17%)
Query: 386 LAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKE 445
LA + AT TV +Q PS P+ PP P +P PLP P+
Sbjct: 873 LAMAVRPATTTV--DSIQAPIPSHTAPRPNPTPAPPPPCFP------VPPPQPLPTPYTY 924
Query: 446 PLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGG--GGDPGPGPAPAPAPPP 503
P A++P PA+ HH+ G G P P P P P P
Sbjct: 925 PAG--------AKQPIPAQ-----------------HHFSSGIPAGFPAPRIGPQPQPHP 959
Query: 504 APDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIK 563
P A P L P LP + + + LG P P+
Sbjct: 960 QPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP----QSPYPYAPQPGVLGQPPPPLH 1015
Query: 564 DAPLP-EKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEPLTI 616
P + P P PS GP PP A AP T +A PLTI
Sbjct: 1016 TQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI 1069
Score = 30.8 bits (68), Expect = 4.3
Identities = 32/117 (27%), Positives = 40/117 (34%), Gaps = 13/117 (11%)
Query: 434 PTSNPLPQ-----PFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGG 488
P +PLP PF P A P P+ R APL R G
Sbjct: 1022 PAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQA--APLTIRGPS--SAGQ 1077
Query: 489 GDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGG 545
P P P+PAP P P R + + P + + A A + SQ GG
Sbjct: 1078 STPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCL----RRGAAAADLLSSSPESQHGG 1130
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/233 (25%), Positives = 81/233 (34%), Gaps = 42/233 (18%)
Query: 382 LLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQ 441
L LAQ P V+ G T P PA+P G A+PP + +K + P P+
Sbjct: 338 LTKPLAQQPGTVKPPVQPPG--TTKP---PAQPLGPAKPPAQQTGSEKPS---SEQPGPK 389
Query: 442 PFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAP 501
+P + + + A++P PA+ T PL + PGP P
Sbjct: 390 ALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA----KAPGPTKTPVQ 442
Query: 502 PPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAP 561
P P K A+ G K A+ P S+ P P
Sbjct: 443 QPGPGKIPAQQ---------AGPGKTSAQQTGPTKPPSQ-----------------LPGP 476
Query: 562 IKDAPL-PEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
K P P P P +P A PS P + PP P A +P G +P
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Score = 40.0 bits (92), Expect = 0.007
Identities = 46/181 (25%), Positives = 68/181 (37%), Gaps = 23/181 (12%)
Query: 434 PTSNPLPQPFKEPLAIMRVENSKA-EKPKPARRKTATDTLIAPLLDRSAHHYKGGGGD-- 490
P S+ + P KE L+ + + + KPA + + ++ L + ++ D
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 491 ----PGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAK-AEAVPAALPASRSQEGG 545
P P P P P PPP P P IL KK A V A P +
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA---- 2458
Query: 546 FLSQAEDCGLGLAPAPIKDAPLPEKEI----PYPTEPARAGLPSGGPFHVRSPPAAPAVA 601
++ E A ++ LP I P P P + +PSG F R P+ P +A
Sbjct: 2459 -VTTLE------TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511
Query: 602 P 602
P
Sbjct: 2512 P 2512
Score = 30.4 bits (67), Expect = 5.6
Identities = 55/252 (21%), Positives = 85/252 (33%), Gaps = 47/252 (18%)
Query: 395 PTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKM---------------KWIPTSNPL 439
P+ G + VDP EP A K K M + +PT
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895
Query: 440 PQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYK------GGGGDPGP 493
P+P ++ S + PK ++ T +T+ L A + G PGP
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954
Query: 494 ----GP------APAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQE 543
GP APAP+ PP P K + +A A ++++
Sbjct: 955 HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014
Query: 544 GGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPL 603
+ + E P PIKD+ EP +A LP+ + P + PL
Sbjct: 1015 APTVKRTE---TEKKPPPIKDSK------SLTAEPQKAVLPT----KLEKSPKPESTCPL 1061
Query: 604 --TPASLGKAEP 613
T ++G +P
Sbjct: 1062 CKTELNIGSKDP 1073
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/233 (25%), Positives = 81/233 (34%), Gaps = 42/233 (18%)
Query: 382 LLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQ 441
L LAQ P V+ G T P PA+P G A+PP + +K + P P+
Sbjct: 338 LTKPLAQQPGTVKPPVQPPG--TTKP---PAQPLGPAKPPAQQTGSEKPS---SEQPGPK 389
Query: 442 PFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAP 501
+P + + + A++P PA+ T PL + PGP P
Sbjct: 390 ALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA----KAPGPTKTPVQ 442
Query: 502 PPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAP 561
P P K A+ G K A+ P S+ P P
Sbjct: 443 QPGPGKIPAQQ---------AGPGKTSAQQTGPTKPPSQ-----------------LPGP 476
Query: 562 IKDAPL-PEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
K P P P P +P A PS P + PP P A +P G +P
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
Score = 40.0 bits (92), Expect = 0.007
Identities = 46/181 (25%), Positives = 68/181 (37%), Gaps = 23/181 (12%)
Query: 434 PTSNPLPQPFKEPLAIMRVENSKA-EKPKPARRKTATDTLIAPLLDRSAHHYKGGGGD-- 490
P S+ + P KE L+ + + + KPA + + ++ L + ++ D
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 491 ----PGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAK-AEAVPAALPASRSQEGG 545
P P P P P PPP P P IL KK A V A P +
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA---- 2458
Query: 546 FLSQAEDCGLGLAPAPIKDAPLPEKEI----PYPTEPARAGLPSGGPFHVRSPPAAPAVA 601
++ E A ++ LP I P P P + +PSG F R P+ P +A
Sbjct: 2459 -VTTLE------TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511
Query: 602 P 602
P
Sbjct: 2512 P 2512
Score = 30.4 bits (67), Expect = 5.6
Identities = 55/252 (21%), Positives = 85/252 (33%), Gaps = 47/252 (18%)
Query: 395 PTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKM---------------KWIPTSNPL 439
P+ G + VDP EP A K K M + +PT
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895
Query: 440 PQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYK------GGGGDPGP 493
P+P ++ S + PK ++ T +T+ L A + G PGP
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954
Query: 494 ----GP------APAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQE 543
GP APAP+ PP P K + +A A ++++
Sbjct: 955 HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014
Query: 544 GGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPL 603
+ + E P PIKD+ EP +A LP+ + P + PL
Sbjct: 1015 APTVKRTE---TEKKPPPIKDSK------SLTAEPQKAVLPT----KLEKSPKPESTCPL 1061
Query: 604 --TPASLGKAEP 613
T ++G +P
Sbjct: 1062 CKTELNIGSKDP 1073
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 48.9 bits (115), Expect = 2e-05
Identities = 65/219 (29%), Positives = 80/219 (36%), Gaps = 24/219 (10%)
Query: 395 PTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVEN 454
P S ++T P +P P PVV P P P P P PL V +
Sbjct: 189 PLPSSSPIKT--PLVSPPGPLTKGNLPVVAPPVPCAP--PPPPPPPPPTPPPLPPASVLS 244
Query: 455 SKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPA------PAPAPPPAPDKK 508
KA KP+ A PLL Y G +P PA PAP PP P
Sbjct: 245 DKAVKPQLAPLHLPPIPPPLPLLPPCG--YPGLKAEPA-SPAQDAQEPPAPPPPLPPYAS 301
Query: 509 HARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLP 568
+ SL P L + +E P P S S F + + G PAP P P
Sbjct: 302 CSPRASLPAPP--LPGVNSSSETPPPLPPKSPS----FQAPPQKAGAQALPAP----PAP 351
Query: 569 EKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPAS 607
P+ + R G P G + PPA PA +P T S
Sbjct: 352 PGSQPF-LQKKRHGRPGAGGGKLNPPPAPPARSPTTELS 389
Score = 39.3 bits (90), Expect = 0.012
Identities = 60/217 (27%), Positives = 77/217 (35%), Gaps = 45/217 (20%)
Query: 410 NPAEPDGAAE--PPVVKRPRKKMKWIPTSNPLPQPFKEPL-AIMRVENSKAEKPKPARRK 466
N +E GAA PP RP PT P P P PL + ++ P P +
Sbjct: 154 NTSEAHGAARTAPP---RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG 210
Query: 467 TATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKK 526
++AP + + P P P P P PPP P +L K
Sbjct: 211 NLP--VVAPPVPCAP---------PPPPPPPPPTPPPLPPAS------------VLSDKA 247
Query: 527 AKAEAVPAALPASRSQEGGFLSQAEDC---GLGLAPA-PIKDA---PLPEKEI-PYPTEP 578
K + P LP L C GL PA P +DA P P + PY +
Sbjct: 248 VKPQLAPLHLPPIPPP----LPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCS 303
Query: 579 ARAGLPS----GGPFHVRSPPAAPAVAPLTPASLGKA 611
RA LP+ G +PP P +P A KA
Sbjct: 304 PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA 340
Score = 32.0 bits (71), Expect = 1.9
Identities = 65/268 (24%), Positives = 86/268 (32%), Gaps = 39/268 (14%)
Query: 360 SLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAE 419
SL R D S L+ D L + Q N + P + +S T A GA+
Sbjct: 37 SLRRAD-PKGRSALLADIQQGTRLRKVTQINDRSAPQI-ESSKGTNKEGGGSANTRGAST 94
Query: 420 PPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDR 479
PP + P P Q + S+A P+ KT + LI P R
Sbjct: 95 PPTLGD--LFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPR-LPNKTISGPLIPPASPR 151
Query: 480 SAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPAS 539
+ + G P P PP P T +P LP+S
Sbjct: 152 LGNTSEAHGAARTAPPRPNVPAPPPP------------------TPPPPPPPLPPPLPSS 193
Query: 540 RSQEGGFLSQAEDCGLGLAPA---PIKDAPLPEKEIPYPTEPA---------RAGLPSGG 587
+ +S G P P+ AP P P PT P +A P
Sbjct: 194 SPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA 253
Query: 588 PFHVRSPPAAPAVAPLTPASLG--KAEP 613
P H+ PP P + L P KAEP
Sbjct: 254 PLHL--PPIPPPLPLLPPCGYPGLKAEP 279
Score = 30.0 bits (66), Expect = 7.3
Identities = 37/148 (25%), Positives = 50/148 (33%), Gaps = 23/148 (15%)
Query: 488 GGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEA--------VPAALPAS 539
GG G GP P P+K + P + T +A A VPA P +
Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
Query: 540 RSQEGGFLSQAEDCGLGLAPAPI-KDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAP 598
L P P+ +P+ + P + LP P +PP P
Sbjct: 179 PPPPPPPL-----------PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
Query: 599 AVAPLTPASLGKAEPLTILSRNATHPLL 626
P TP L P ++LS A P L
Sbjct: 228 PPPPPTPPPL---PPASVLSDKAVKPQL 252
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 48.1 bits (113), Expect = 3e-05
Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 23/204 (11%)
Query: 439 LPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPA 498
LP+ E A + NS +P R ++ + T I + R G DP
Sbjct: 435 LPKDVSEDPATPKDSNSLKARP---RSRSYSSTSIEEAMKR--------GEDP------- 476
Query: 499 PAPPPAPDKKHARHFSLDVH----PYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDC- 553
P PPP P K H+R SLD++ P + TK PA P + +S+AE
Sbjct: 477 PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLP 536
Query: 554 GLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
L AP+ ++ +K++ Y P++ P + + P+ A PAS +P
Sbjct: 537 QLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKP 596
Query: 614 LTILSRNATHPLLHINTLYEAREE 637
+ + ++ I T +E
Sbjct: 597 HPTVQKQSSKQKKAIQTAIRKNKE 620
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 48.1 bits (113), Expect = 3e-05
Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 23/204 (11%)
Query: 439 LPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPA 498
LP+ E A + NS +P R ++ + T I + R G DP
Sbjct: 436 LPKDVSEDPATPKDSNSLKARP---RSRSYSSTSIEEAMKR--------GEDP------- 477
Query: 499 PAPPPAPDKKHARHFSLDVH----PYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDC- 553
P PPP P K H+R SLD++ P + TK PA P + +S+AE
Sbjct: 478 PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLP 537
Query: 554 GLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
L AP+ ++ +K++ Y P++ P + + P+ A PAS +P
Sbjct: 538 QLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKP 597
Query: 614 LTILSRNATHPLLHINTLYEAREE 637
+ + ++ I T +E
Sbjct: 598 HPTVQKQSSKQKKAIQTAIRKNKE 621
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 46.6 bits (109), Expect = 8e-05
Identities = 54/191 (28%), Positives = 70/191 (36%), Gaps = 24/191 (12%)
Query: 473 IAPLLDRSAHHYKGGGGDPGPGPAPAPAP--------PPAPDKKH-ARHFSLDVHPY--- 520
+ PL+ + G PGPGP P P PPAP +H AR D+ P
Sbjct: 197 VTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQT 256
Query: 521 -ILGTKKAKA---EAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPT 576
I G A AVP A P S + G Q G+G P + + P P
Sbjct: 257 PIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPR 316
Query: 577 EPAR-AGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEPLTILSRNATHPLLHINTLYEAR 635
P GLP G + P P L + G+ EP L P +H + ++ R
Sbjct: 317 GPVTPGGLPPRG--LLGDAPNDPRGGTLLSVT-GEVEPRGYLGPPHQGPPMHHASGHDTR 373
Query: 636 ----EEEDGGP 642
E GGP
Sbjct: 374 GPSSHEMRGGP 384
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 46.2 bits (108), Expect = 1e-04
Identities = 50/144 (34%), Positives = 59/144 (40%), Gaps = 24/144 (16%)
Query: 491 PGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA 550
P G A PA PP K P + G+ ++ VP LP S E + +A
Sbjct: 1213 PPEGEARKPAKPPVSPKP----VLTQPVPKLQGSPTPTSKKVP--LPGPGSPE---VKRA 1263
Query: 551 EDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGG------PFHVRSPPAAPAVAPLT 604
P P+ P P P P + A AGLPSG P R PPAA A P T
Sbjct: 1264 HG-----TPPPVSPKPPPPPTAPKPVK-AVAGLPSGSAGPSPAPSPARQPPAALAKPPGT 1317
Query: 605 PASLGKAEPLTILSRNATHPLLHI 628
P SLG A P S A P LH+
Sbjct: 1318 PPSLG-ASPAKPPSPGA--PALHV 1338
Score = 37.7 bits (86), Expect = 0.035
Identities = 38/130 (29%), Positives = 51/130 (39%), Gaps = 10/130 (7%)
Query: 411 PAEPDGAAEPPVVKRPRKKMKW--IPTSNPLPQPFKEPLAIMRVENSKAE-KPKPARRKT 467
PA+P + PV+ +P K++ PTS +P P + R + PKP T
Sbjct: 1221 PAKPP-VSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPT 1279
Query: 468 ATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKA 527
A P ++ G P P P+PA PP A K SL P + A
Sbjct: 1280 A------PKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGA 1333
Query: 528 KAEAVPAALP 537
A VPA P
Sbjct: 1334 PALHVPAKPP 1343
Score = 35.0 bits (79), Expect = 0.23
Identities = 58/237 (24%), Positives = 74/237 (31%), Gaps = 61/237 (25%)
Query: 391 HDATPTVR------DSGVQTVDPSANPAEP---DGAAEPPVVKRPRKKMKWIPTSNPLPQ 441
H+ T TVR +G + P PAEP D A PP+ P +
Sbjct: 1171 HNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLP----------PPEGEARK 1220
Query: 442 PFKEPLAIMRVENSKAEK----PKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAP 497
P K P++ V K P P +K PL + K G P P
Sbjct: 1221 PAKPPVSPKPVLTQPVPKLQGSPTPTSKKV-------PLPGPGSPEVKRAHGTPPPVSPK 1273
Query: 498 APAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGL 557
P PP AP A + G A PA PA +
Sbjct: 1274 PPPPPTAPKPVKA----------VAGLPSGSAGPSPAPSPARQP---------------- 1307
Query: 558 APAPIKDAP-LPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
PA + P P P +P G P+ HV + P A A A+ A P
Sbjct: 1308 -PAALAKPPGTPPSLGASPAKPPSPGAPA---LHVPAKPPRAAAAAAAAAAAPPAPP 1360
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/234 (26%), Positives = 84/234 (35%), Gaps = 51/234 (21%)
Query: 402 VQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVE-------- 453
VQ + P P G+ +P ++ P K + I S+ P A+ V
Sbjct: 816 VQEGSRATMPQVPGGSVKPKIMS-PEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSP 874
Query: 454 -NSKAE-KPKPARRKTA---TDTLIAPLLDRSAHHYKGGGG-----DPGPGPAPAPAPPP 503
N K + KPK RK++ + ++ + S+ G G DP G PAP PPP
Sbjct: 875 ANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP 934
Query: 504 APDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLG--LAPAP 561
P + P PA RS DC G L +P
Sbjct: 935 VP-------------------------SPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSP 969
Query: 562 IKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSP--PAAPAVAPLTPASLGKAEP 613
+ P PE IP+ + P P P SP P +P PL P L +EP
Sbjct: 970 VFPPPPPEALIPFCSPPDWCLSP---PRPALSPILPDSPVSLPLPPPLLPSSEP 1020
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 45.1 bits (105), Expect = 2e-04
Identities = 56/232 (24%), Positives = 86/232 (37%), Gaps = 48/232 (20%)
Query: 392 DATPTVRDSGVQTVDPS-----ANPAEPDGAAEPPVVKRPRKKMKWI-PTSNPLP-QPFK 444
D ++ GV+ +D + + A + PP ++ P + P +PLP QP
Sbjct: 507 DGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPLPEQPLD 566
Query: 445 EPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGG------------GGDPG 492
P A + +P P R T ++P SA G G PG
Sbjct: 567 SPAAPALSPSGLGLQPGPERTSTTKSKELSP---GSAQKGSPGSSQGTACAGTQPGAQPG 623
Query: 493 --PGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA 550
PG +P+P+ PPA D P+ L K +P +P Q G Q+
Sbjct: 624 AQPGASPSPSQPPA-----------DQSPHTLRKVSKKLAPIPPKVPF--GQPGAMADQS 670
Query: 551 EDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAP 602
P+P+ +P P P+ P+ GL + + S +PA AP
Sbjct: 671 AG-----QPSPVSLSPTP------PSTPSPYGLSYPQGYSLASGQLSPAAAP 711
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 44.7 bits (104), Expect = 3e-04
Identities = 64/268 (23%), Positives = 88/268 (32%), Gaps = 45/268 (16%)
Query: 385 ALAQSNHDATPTVRDSGVQ---TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQ 441
A+ H + P VR + +Q T PS+ P GA K P +
Sbjct: 1558 AVTVRGHGSLP-VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
Query: 442 PFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS-----------AHHYKGGGGD 490
P S P A ++PL RS A H + G
Sbjct: 1617 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
Query: 491 PGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA 550
P P P P+ PP P A+H T ++ A+P PA+ S LS A
Sbjct: 1677 ASPQPHPLPSAPPRP----AQH----------TTMATRSPALPPETPAAAS-----LSTA 1717
Query: 551 EDCGLGLAPAPIKDAPLPEK---EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-- 605
D GL P ++ P + +P T A + + P P A+ PL P
Sbjct: 1718 TD-GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQA 1776
Query: 606 -----ASLGKAEPLTILSRNATHPLLHI 628
+L P T + HP HI
Sbjct: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 44.7 bits (104), Expect = 3e-04
Identities = 64/268 (23%), Positives = 88/268 (32%), Gaps = 45/268 (16%)
Query: 385 ALAQSNHDATPTVRDSGVQ---TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQ 441
A+ H + P VR + +Q T PS+ P GA K P +
Sbjct: 1630 AVTVRGHGSLP-VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1688
Query: 442 PFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRS-----------AHHYKGGGGD 490
P S P A ++PL RS A H + G
Sbjct: 1689 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1748
Query: 491 PGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA 550
P P P P+ PP P A+H T ++ A+P PA+ S LS A
Sbjct: 1749 ASPQPHPLPSAPPRP----AQH----------TTMATRSPALPPETPAAAS-----LSTA 1789
Query: 551 EDCGLGLAPAPIKDAPLPEK---EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-- 605
D GL P ++ P + +P T A + + P P A+ PL P
Sbjct: 1790 TD-GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQA 1848
Query: 606 -----ASLGKAEPLTILSRNATHPLLHI 628
+L P T + HP HI
Sbjct: 1849 TTLPAQTLSPVLPFTPAAMTQAHPPTHI 1876
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 44.3 bits (103), Expect = 4e-04
Identities = 59/202 (29%), Positives = 65/202 (32%), Gaps = 35/202 (17%)
Query: 411 PAEPDGAAEPPVVKRPRKK-MKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTAT 469
PA P A PP VKRP M +P PLP+ P P P T
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP--------PPGGLPLPPMPPTGP 269
Query: 470 DTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKA 529
AP G PGP P PAP P + VHP G
Sbjct: 270 ----AP------------SGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP 313
Query: 530 EAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYP-TEPARAGL--PSG 586
P A P G A PAP P P P P P G+ P
Sbjct: 314 GVHPPA-PGVHPPTSGVHPPAPGVH---PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS 369
Query: 587 GPFHVRSP---PAAPAVAPLTP 605
H ++P PAAPAV P P
Sbjct: 370 AGVHPQAPGVHPAAPAVHPQAP 391
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/252 (24%), Positives = 97/252 (38%), Gaps = 35/252 (13%)
Query: 407 PSANPAEPDGAAEPPVVKRPRKKMKWIPTS------NPLPQPFKEPLAIMRVENSKAEKP 460
PS+ P P + V+ R++ + TS + P+P+ P + + P
Sbjct: 140 PSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQ----EGGCP 195
Query: 461 KPARRKTATDTLIAPL-LDRSAHHYKGGGGDPGPGP-----APAPAPPPAPDKKHARHFS 514
+P R++ + + P+ L R A P P AP+P PP P + +
Sbjct: 196 RPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSA 255
Query: 515 LDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPA-PIKDAPLPEKEIP 573
D L ++ A A+ L + Q LS+A L L P P+ P P P
Sbjct: 256 SDPSLDFLRAQQETANAI-RELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP 314
Query: 574 YPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEPLTILSRNATHPLLHINTLYE 633
P P R LP P AP V +TP EP+++++ ++ +
Sbjct: 315 PPPPPPRPVLP----------PPAPKVE-ITP------EPVSVVAAVVDGAVVAARGVII 357
Query: 634 AREEEDGGPRLP 645
A E+G PR P
Sbjct: 358 APRSEEGAPRPP 369
Score = 35.8 bits (81), Expect = 0.13
Identities = 46/189 (24%), Positives = 66/189 (34%), Gaps = 23/189 (12%)
Query: 437 NPLPQPFKEPLAIMRVENS-KAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGP 495
N + KE LA RV +S + P +A + I +L G G P
Sbjct: 81 NDFKRRTKEKLA--RVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPA 138
Query: 496 APAPAPPP----------APDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGG 545
AP+ PPP + D++ R H +K + P A P+ QEGG
Sbjct: 139 APSSQPPPPSACPQRYVLSEDRREDRRADTSAH-----SKAGSSSPEPWARPSCTPQEGG 193
Query: 546 FLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPF-HVRSPPAAPAVAPLT 604
E +P P P+ + P LP P V P +P P
Sbjct: 194 CPRPKE----RESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRP 249
Query: 605 PASLGKAEP 613
P +L ++P
Sbjct: 250 PPTLSASDP 258
Score = 30.4 bits (67), Expect = 5.6
Identities = 33/135 (24%), Positives = 52/135 (38%), Gaps = 27/135 (20%)
Query: 379 VRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNP 438
+RQ LA L+++ P + + V ++ P P P PV+ P K++ P
Sbjct: 280 LRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP---- 335
Query: 439 LPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPA 498
EP++++ A A +IAP + A P P PAP
Sbjct: 336 ------EPVSVVAAVVDGAVV-------AARGVIIAPRSEEGA---------PRPPPAPL 373
Query: 499 PAPPPAPDKKHARHF 513
P P +P K + F
Sbjct: 374 P-PHDSPPHKRRKGF 387
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 43.5 bits (101), Expect = 6e-04
Identities = 58/246 (23%), Positives = 78/246 (31%), Gaps = 41/246 (16%)
Query: 404 TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPA 463
T PS+ P GA K P + P S P
Sbjct: 1579 TASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTV 1638
Query: 464 RRKTATDTLIAPLLDRS-----------AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARH 512
A ++PL RS A H + G P P P P+ PP P A+H
Sbjct: 1639 AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRP----AQH 1694
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEK-- 570
T ++ A+P PA+ S LS A D GL P ++ P +
Sbjct: 1695 ----------TTMATRSPALPPETPAAAS-----LSTATD-GLAATPFMSLESTRPSQLL 1738
Query: 571 -EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-------ASLGKAEPLTILSRNAT 622
+P T A + + P P A+ PL P +L P T +
Sbjct: 1739 SGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQA 1798
Query: 623 HPLLHI 628
HP HI
Sbjct: 1799 HPPTHI 1804
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 43.5 bits (101), Expect = 6e-04
Identities = 58/246 (23%), Positives = 78/246 (31%), Gaps = 41/246 (16%)
Query: 404 TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPA 463
T PS+ P GA K P + P S P
Sbjct: 1651 TASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTV 1710
Query: 464 RRKTATDTLIAPLLDRS-----------AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARH 512
A ++PL RS A H + G P P P P+ PP P A+H
Sbjct: 1711 AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRP----AQH 1766
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEK-- 570
T ++ A+P PA+ S LS A D GL P ++ P +
Sbjct: 1767 ----------TTMATRSPALPPETPAAAS-----LSTATD-GLAATPFMSLESTRPSQLL 1810
Query: 571 -EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-------ASLGKAEPLTILSRNAT 622
+P T A + + P P A+ PL P +L P T +
Sbjct: 1811 SGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQA 1870
Query: 623 HPLLHI 628
HP HI
Sbjct: 1871 HPPTHI 1876
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 43.5 bits (101), Expect = 6e-04
Identities = 58/246 (23%), Positives = 78/246 (31%), Gaps = 41/246 (16%)
Query: 404 TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPA 463
T PS+ P GA K P + P S P
Sbjct: 1579 TASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTV 1638
Query: 464 RRKTATDTLIAPLLDRS-----------AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARH 512
A ++PL RS A H + G P P P P+ PP P A+H
Sbjct: 1639 AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRP----AQH 1694
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEK-- 570
T ++ A+P PA+ S LS A D GL P ++ P +
Sbjct: 1695 ----------TTMATRSPALPPETPAAAS-----LSTATD-GLAATPFMSLESTRPSQLL 1738
Query: 571 -EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-------ASLGKAEPLTILSRNAT 622
+P T A + + P P A+ PL P +L P T +
Sbjct: 1739 SGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQA 1798
Query: 623 HPLLHI 628
HP HI
Sbjct: 1799 HPPTHI 1804
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 43.5 bits (101), Expect = 6e-04
Identities = 58/246 (23%), Positives = 78/246 (31%), Gaps = 41/246 (16%)
Query: 404 TVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPA 463
T PS+ P GA K P + P S P
Sbjct: 1651 TASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTV 1710
Query: 464 RRKTATDTLIAPLLDRS-----------AHHYKGGGGDPGPGPAPAPAPPPAPDKKHARH 512
A ++PL RS A H + G P P P P+ PP P A+H
Sbjct: 1711 AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRP----AQH 1766
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEK-- 570
T ++ A+P PA+ S LS A D GL P ++ P +
Sbjct: 1767 ----------TTMATRSPALPPETPAAAS-----LSTATD-GLAATPFMSLESTRPSQLL 1810
Query: 571 -EIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTP-------ASLGKAEPLTILSRNAT 622
+P T A + + P P A+ PL P +L P T +
Sbjct: 1811 SGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQA 1870
Query: 623 HPLLHI 628
HP HI
Sbjct: 1871 HPPTHI 1876
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 43.1 bits (100), Expect = 8e-04
Identities = 45/133 (33%), Positives = 53/133 (39%), Gaps = 28/133 (21%)
Query: 485 KGGGG------DPGPGPAPAPAPPP------------APDKKHARHFSLDVHPYILGTKK 526
KGG G D P PA PAPP APD AR P + +
Sbjct: 397 KGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARR-----SPDAVASPG 451
Query: 527 AKAEAVPAA---LPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPT-EPARAG 582
A A A PA L ++ + EGG A+ G AP P +P P P P EPA G
Sbjct: 452 APAPA-PAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCG 510
Query: 583 LPSGGPFHVRSPP 595
+P G SPP
Sbjct: 511 VPEPGAAAGPSPP 523
Score = 37.4 bits (85), Expect = 0.046
Identities = 71/259 (27%), Positives = 84/259 (32%), Gaps = 50/259 (19%)
Query: 445 EPLAIMRVENSKAEKPKPARRKTATDT----LIAP--LLDRSAHHYKGGGGDPGPGPAPA 498
+P I R E K EK K K + L +P L SA G G P P
Sbjct: 188 DPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEP- 246
Query: 499 PAPPPAPDKKHARHFS--LDVHPYILGTKKAKAEAVPAALPASRSQEGGFL-------SQ 549
P PPP K H S P G A PA P+ RS G
Sbjct: 247 PEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKD 306
Query: 550 AEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVR-----SPP--------A 596
A CG G A A + E AGLP PF V SPP A
Sbjct: 307 AASCGPGAAVAAV--------------ERGAAGLPKASPFSVESLLSDSPPRRKAASNAA 352
Query: 597 APAVAPLTPASLGKAEPLTILSRN--ATHPLLHINTLYEAREEEDGGPRL---PQDVGDL 651
A A A L A P T++ + +P+ + GG L P+D
Sbjct: 353 AAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPA 412
Query: 652 IAIP--APQQILIATFDEP 668
A+P P Q F P
Sbjct: 413 PAVPPAPPAQASFGAFSGP 431
Score = 30.0 bits (66), Expect = 7.3
Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 411 PAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATD 470
PA D P V P + + S P P + R ++ A PA
Sbjct: 404 PAPKDAPPAPAVPPAPPAQASFGAFSGPGGAP--DSAFARRSPDAVASPGAPAPAP---- 457
Query: 471 TLIAPLLD-RSAHHYKGGGGD-----------PGPGPAPAPAP-PPAPDKKHA 510
AP D SA +GGGGD P P P+P P P PP+P ++ A
Sbjct: 458 ---APFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPA 507
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/233 (25%), Positives = 80/233 (34%), Gaps = 46/233 (19%)
Query: 379 VRQLLAALAQSNHDATPTVRDSGVQTVDPSANP--AEPDGAAEPPVVKRPRKKMKWIPTS 436
V L +L S+ D P+ R SG Q + P + P P P K P +
Sbjct: 626 VSSSLTSLCSSSSDPAPSDR-SGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAA 684
Query: 437 NPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPA 496
L P P + + S P P + T T +P++ + P P P
Sbjct: 685 PALAAPAVVPGPVSTTDASPQSPPTP--QTTLTPLQESPVISKDQ--------SPPPSPP 734
Query: 497 PAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLG 556
P+ PPP P K K E V A AS + E +D
Sbjct: 735 PSYHPPPPPTK--------------------KPEVVVEAPSASETAE----EPLQDPNWP 770
Query: 557 LAPAP--------IKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVA 601
P P + D P PE+ P AG PSG P V SP A+ + A
Sbjct: 771 PPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAG-PSGSPELVSSPAASSSSA 822
Score = 32.0 bits (71), Expect = 1.9
Identities = 45/183 (24%), Positives = 69/183 (37%), Gaps = 21/183 (11%)
Query: 501 PPPAPDKKHARH-FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCG----- 554
PPP P + H+ H L V LG LP + G + A C
Sbjct: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPAN 556
Query: 555 ---LGLAPAPIKDAP-LPEKEI-PYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLG 609
GL+P + P PE+ + P +++G P+ P + PPA+P A
Sbjct: 557 SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPG-----KAQPP 611
Query: 610 KAEPLTILSRNATHPLLHINTLYEAREE----EDGGPRLPQDVGDLIAIPAPQQILIATF 665
K E +T L + +L + + + GP++ +GD IP P + A F
Sbjct: 612 KPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP-PHPKVPAPF 670
Query: 666 DEP 668
P
Sbjct: 671 SPP 673
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 42.7 bits (99), Expect = 0.001
Identities = 73/299 (24%), Positives = 99/299 (33%), Gaps = 42/299 (14%)
Query: 393 ATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRV 452
ATP G+ T P P P AA PP K P P P P
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTP--AATPPSPKGGPATPP--PKGAPTPPAATPP------ 1272
Query: 453 ENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARH 512
+ K P + ++ P + G P P A P+P +P +
Sbjct: 1273 -SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK- 1330
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPL----P 568
P + +PA P+S+ GG + + G P P P P
Sbjct: 1331 -GAPTPPAVTPPSPKGTPTLPATTPSSK---GGPTTPSSKEG----PTPPAATPSHKGGP 1382
Query: 569 EKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASL-GKAEPLTILSRNATHPLLH 627
P P P G P P +P AP TP + G A P + T P +
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP---SKGDLTPPAVT 1439
Query: 628 INTLYE--AREEEDGGPRLPQDVGD--LIAI--------PAPQQILIATFDEPRTVVST 674
+L + A GGP P GD L A+ PAP+Q +AT P+ +T
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ--VATSSSPKKAPAT 1496
Score = 42.4 bits (98), Expect = 0.001
Identities = 66/247 (26%), Positives = 84/247 (34%), Gaps = 34/247 (13%)
Query: 392 DATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNP---LPQPFKEPLA 448
D+ + S T+ A+ P G + P KRP K P L P A
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 449 IMRVENSKA-----------EKPKPARRKTA-TDTLIAPLLDRSAHHYKGGGGDPGPGPA 496
ENS + P P K A T + + PL + P
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 497 PAPAPPPA-PDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA----E 551
P P PA P K A S+ KKA+A P +PAS S +G A
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSS----SPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 552 DCGLGLAPAPIKDAPLPEKEIPYPTEPARAG-----LPSGGPFHVRSPPAAPAVAPLTPA 606
G P+P K AP P P T P+ G P G P + P +P P TP+
Sbjct: 950 PKGGPATPSP-KWAPTP----PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 607 SLGKAEP 613
G P
Sbjct: 1005 PKGAPTP 1011
Score = 39.3 bits (90), Expect = 0.012
Identities = 61/229 (26%), Positives = 73/229 (31%), Gaps = 55/229 (24%)
Query: 393 ATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKR-----PRKKMKWIPTSNPLPQPFKEPL 447
ATP G T P P P AA PP K P K P + P P P
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATP-PSP----- 1136
Query: 448 AIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAP--APPPAP 505
+ A P T T +P KGG P P AP A PP+P
Sbjct: 1137 -----KGGLATPPPKGAPTTPAATPPSP---------KGGLATPPPKGAPTTPAATPPSP 1182
Query: 506 DKKHARHFSLDVHPYILGTKKAK-AEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKD 564
L T K A PAA P S +GG + + G P
Sbjct: 1183 KGG-------------LATPSPKGAPTTPAATPPS--PKGGLATPSPK---GAPTTPAAT 1224
Query: 565 APLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
P P+ + P+ P G P + P +P P TP G P
Sbjct: 1225 PPSPKGGLATPS-------PKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Score = 39.3 bits (90), Expect = 0.012
Identities = 70/274 (25%), Positives = 85/274 (31%), Gaps = 59/274 (21%)
Query: 393 ATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKR--PRKKMKWIPTSNPLPQPFKEPLAIM 450
ATP G+ T P P P AA PP K K PT+ P P +
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTP--AATPPSPKGGLATPSPKGAPTTPAATPP--SPKGGL 1232
Query: 451 RVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPPAPDKKHA 510
+ K PA + KGG P P AP P P K
Sbjct: 1233 ATPSPKGAPTTPAATPPSP---------------KGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 511 RHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEK 570
L T K PA + S +GG A +P K AP P
Sbjct: 1278 -----------LATPPHKGAPNPAVVTPP-SPKGG-----------PATSPPKGAPTPPA 1314
Query: 571 EIP-----YPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEPLTILSRNATHPL 625
P P P G P+ SP P + TP+S K P T S+ P
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS--KGGPTTPSSKEGPTP- 1371
Query: 626 LHINTLYEAREEEDGGPRL-PQDVGDLIAIPAPQ 658
A GGP + P AIP+P+
Sbjct: 1372 ------PAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
Score = 37.4 bits (85), Expect = 0.046
Identities = 66/243 (27%), Positives = 81/243 (33%), Gaps = 34/243 (13%)
Query: 398 RDSGVQTVDPSANPAEPDGAAEPPVVKRPRKK-----MKWIPTSNPLPQPF-KEPLAIMR 451
+DS T P+ P P GA P V K K PT + + PF KE A
Sbjct: 847 KDSPATTHSPT--PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 452 VENSKA-----EKPKPARRKTATDTLIAPLLDRSAH--------HYKGGGGDPGPGPAPA 498
+ + A PK AR A + A + A KGG P P AP
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Query: 499 P--APPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQA-----E 551
P A PP+P A P T A P PA+ S +G A
Sbjct: 965 PPAATPPSPKGGPATP-----SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 552 DCGLGLAPAPIKDAPLPEKEIPYPT-EPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGK 610
P P + P P P PA LP G P + +P P TP+ G
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 611 AEP 613
P
Sbjct: 1080 PTP 1082
Score = 37.0 bits (84), Expect = 0.060
Identities = 54/221 (24%), Positives = 63/221 (28%), Gaps = 50/221 (22%)
Query: 404 TVDPSANPAEPD--GAAEPPVVKRPRKK-------MKWIPTSNPLPQPFKEPLAIMRVEN 454
T P PA P GA PP P K KW PT P +
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP-----------S 972
Query: 455 SKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAP--APPPAPDKKHARH 512
K P+ + T P KGG P P AP P PP+P A
Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSP------KGGPATPSPKGAPTPPAVTPPSPKGSPA-- 1024
Query: 513 FSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEI 572
P+ G A PAA P S P P P +
Sbjct: 1025 ----ATPFPKG-----ASTPPAATPPSPKGSPA-----------ATPLPKGAPTTPAATL 1064
Query: 573 PYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
P P G P + P +P P TP+ G P
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105
Score = 34.7 bits (78), Expect = 0.30
Identities = 57/233 (24%), Positives = 87/233 (37%), Gaps = 37/233 (15%)
Query: 385 ALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFK 444
A+ S + P+ ++ + P+ P A PP V P + K T P P
Sbjct: 1584 AVTPSTYKGAPSPKEL---LIPPAVTSPSPKEAPTPPAVTPPSPE-KGPATPAPKGTPTS 1639
Query: 445 EPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPPP- 503
P+ +++S + AT P + KG APAP P
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGAT----VPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695
Query: 504 --APDKKHARHFSLDVHPYILGTKKAKAEAVPAAL-PASRSQEGGFLSQAEDCGLGLAPA 560
AP +K + TKK+ A + P P++++ G LS +APA
Sbjct: 1696 ITAPTRKGPQ------------TKKSSATSPPICPDPSAKNGSKGPLST-------VAPA 1736
Query: 561 PIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
P+ LP ++ T A+ S P +PP + A PLT A+ K P
Sbjct: 1737 PL----LPVQKDSSKT--AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783
Score = 32.7 bits (73), Expect = 1.1
Identities = 63/244 (25%), Positives = 81/244 (33%), Gaps = 54/244 (22%)
Query: 394 TPTVRDSGVQTVDPSANPAEPDG-------AAEPPVVKRPRKKMKWIPTSNP-----LPQ 441
TP T P PA P A PP K P + +S+P P
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Query: 442 PFKEPLAIMRVENSKAEKPK-PARRK---TATDTLI-----APLLDRSAHHYKGGGGDPG 492
P P + +S E P P+ R+ T TL+ A L + A P
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL-IPPAMTVPS 1557
Query: 493 PGPAPA-PAP---PPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLS 548
P PA P P P P K A G K +P A+ + +E
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE----- 1612
Query: 549 QAEDCGLGLAPAP-IKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAV---APLT 604
AP P P PEK P PA G P+ SPP P+ +P +
Sbjct: 1613 ---------APTPPAVTPPSPEKG---PATPAPKGTPT-------SPPVTPSSLKDSPTS 1653
Query: 605 PASL 608
PAS+
Sbjct: 1654 PASV 1657
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 17/140 (12%)
Query: 407 PSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRK 466
PS P P ++ PP V+R P P P P I RV + P+P + K
Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSS---PQRRQSPSPSTRP--IRRVSRT----PEPKKIK 734
Query: 467 TATDTLIAPLLDRSAHHYKGGGGDPGPGPAPAPAPP-PAPDKKHARHFSLDVHPYILGTK 525
A +P R + G P P PAPP P + + ++S V K
Sbjct: 735 KAASP--SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV-----PVK 787
Query: 526 KAKAEAVPAALPASRSQEGG 545
KAK+ + P + QEGG
Sbjct: 788 KAKSPTPSPSPPRNSDQEGG 807
Score = 30.0 bits (66), Expect = 7.3
Identities = 52/219 (23%), Positives = 77/219 (35%), Gaps = 33/219 (15%)
Query: 403 QTVDPSANPAEPDGAAEPPVVKRPRKKMKW------IPTSN----PLPQPFKEPLAIMRV 452
+T S +PA P+ + P + P K+K TS+ P P+P EP
Sbjct: 204 RTKSRSPSPA-PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE 262
Query: 453 ENSKAEKPKP-------ARRKTATDTLI-APLLDRSAHHYKGGGGDPGPGPAPAPAPPPA 504
+NSK EK K +R K+ + T +P R ++ P P+P P+
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPS 322
Query: 505 PDKK-HARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIK 563
P ++ R + + A+L S S S++ P K
Sbjct: 323 PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS---------PPKK 373
Query: 564 DAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAP 602
P K P R PS P R P+ PA P
Sbjct: 374 ----PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408
>gi|33186895 selenoprotein V [Homo sapiens]
Length = 346
Score = 42.4 bits (98), Expect = 0.001
Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 16/197 (8%)
Query: 379 VRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNP 438
+R L L S +P V + P+ P P A P +V P WIPT P
Sbjct: 43 IRTLTPVLTPSPAGTSPLVLTPAPAQI-PTLVPT-PALARIPRLVPPPAPA--WIPTPVP 98
Query: 439 LPQPFKEPLAI---MRVENSKAEKPKPARRKTATDTLIA-PLLDRSAHHYKGGGGDPGPG 494
P P + P + R P PA + A P+LD Y P
Sbjct: 99 TPVPVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVLD----SYLAPALPLDPP 154
Query: 495 PAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEG---GFLSQAE 551
P PAP P P++ SL + P + +P P + + G F +A+
Sbjct: 155 PEPAPELPLLPEEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFRAD 214
Query: 552 DCGLGLAPAPIKDAPLP 568
+GLA PI +P+P
Sbjct: 215 PSAIGLADPPI-PSPVP 230
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/145 (29%), Positives = 53/145 (36%), Gaps = 17/145 (11%)
Query: 485 KGGGGDPG------PGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPA 538
+GGGG PG P P P P PPPAP ++ P G + ALP
Sbjct: 4 RGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPP 63
Query: 539 SRSQEGG----FLSQAEDCGLGLAP---APIKDAPLPEKEIPYP-TEPARAGLPSGGP-- 588
+ EGG S+ CG P + K +P E P PA P+ GP
Sbjct: 64 EAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKV 123
Query: 589 -FHVRSPPAAPAVAPLTPASLGKAE 612
F R + PA P G E
Sbjct: 124 SFSCRGAASGPAPGPGPAEEAGSEE 148
Score = 37.4 bits (85), Expect = 0.046
Identities = 55/175 (31%), Positives = 67/175 (38%), Gaps = 23/175 (13%)
Query: 438 PLPQPFKEPLAIMRVENSKAEK--PKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGP 495
P P P + AI ++ + A P+ AR L +P L R P PGP
Sbjct: 716 PPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRR----------PPPGP 765
Query: 496 APA-----PAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASR-SQEGGFLSQ 549
APA P PP +P A + PY G A A P ALPA R S+ LS
Sbjct: 766 APAAASPGPPPPASPPGAPASPRAPRTSPY--GGLPAAPLAGP-ALPARRLSRASRPLSA 822
Query: 550 AEDCGLGLAPAPIKDAPLPEKEIPY--PTEPARAGLPSGGPFHVRSPPAAPAVAP 602
++ AP P P PT ARA PS SP AA + P
Sbjct: 823 SQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDP 877
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 19/149 (12%)
Query: 501 PPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLA-- 558
PPP P ++ + P L P A+ A S G A GLG A
Sbjct: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
Query: 559 ---------PAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLG 609
P P AP P P P PA A P+ GP PA P +A + G
Sbjct: 66 ALLLHPPPPPPPATAAPPPPP--PPPPPPASAAAPASGP------PAPPGLAAGPGPAGG 117
Query: 610 KAEPLTILSRNATHPLLHINTLYEAREEE 638
P + +A P H ++ +E+E
Sbjct: 118 APTPALVAGSSAAAPFPHGDSALNEQEKE 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,536,829
Number of Sequences: 37866
Number of extensions: 1692730
Number of successful extensions: 17725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 13290
Number of HSP's gapped (non-prelim): 3446
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.