Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 16306537
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
(801 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 1614 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 974 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 974 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 922 0.0
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 920 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 912 0.0
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 909 0.0
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 890 0.0
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 889 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 882 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 832 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 762 0.0
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 743 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 722 0.0
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 549 e-156
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 401 e-111
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 393 e-109
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 360 3e-99
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 353 5e-97
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 340 3e-93
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 256 8e-68
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 250 3e-66
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 246 8e-65
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 246 8e-65
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 244 3e-64
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 238 2e-62
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 230 4e-60
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 224 2e-58
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 224 2e-58
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 219 6e-57
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 1614 bits (4180), Expect = 0.0
Identities = 801/801 (100%), Positives = 801/801 (100%)
Query: 1 MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRS 60
MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRS
Sbjct: 1 MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRS 60
Query: 61 WVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQ 120
WVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQ
Sbjct: 61 WVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQ 120
Query: 121 RLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPV 180
RLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPV
Sbjct: 121 RLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPV 180
Query: 181 GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV 240
GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV
Sbjct: 181 GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV 240
Query: 241 IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD 300
IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD
Sbjct: 241 IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD 300
Query: 301 LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL 360
LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL
Sbjct: 301 LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL 360
Query: 361 EMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN 420
EMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN
Sbjct: 361 EMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN 420
Query: 421 NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV 480
NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV
Sbjct: 421 NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV 480
Query: 481 TIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN 540
TIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN
Sbjct: 481 TIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN 540
Query: 541 PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD
Sbjct: 541 PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
Query: 601 GHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHE 660
GHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHE
Sbjct: 601 GHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHE 660
Query: 661 NIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNS 720
NIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNS
Sbjct: 661 NIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNS 720
Query: 721 TVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDW 780
TVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDW
Sbjct: 721 TVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDW 780
Query: 781 GPRFRKLAELYGASEGPAPLW 801
GPRFRKLAELYGASEGPAPLW
Sbjct: 781 GPRFRKLAELYGASEGPAPLW 801
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 974 bits (2518), Expect = 0.0
Identities = 491/777 (63%), Positives = 596/777 (76%), Gaps = 7/777 (0%)
Query: 22 FWGLMDLTTTVLSDTPTPQGELEALLSDKP---QSHQRTKRSWVWNQFFVLEEYTGTDPL 78
F + L L + Q EL S KP RTKRSWVWNQFFVLEEY G+DPL
Sbjct: 8 FCHFLQLIALFLCFSGMSQAELSRSRS-KPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPL 66
Query: 79 YVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALD 138
YVGKLHSD+D+GDGSIKYILSGEGA +F ID+ TGDIHA +RLDREE+A YTLRAQALD
Sbjct: 67 YVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALD 126
Query: 139 RRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYG 198
R T +P+EPESEF+IKIQDINDNEPKFLDGPY A VPEMSPVGTSV+QVTATDADDPTYG
Sbjct: 127 RLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYG 186
Query: 199 NSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTT 258
NSARVVYSILQGQPYFSV+ KTGVI+TAL NMDREAK+ Y ++IQAKDM GQ GGL+GTT
Sbjct: 187 NSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTT 246
Query: 259 TVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDG 318
+V +TL+DVNDNPPRFP++ YQ +V ES P++S V R+ A D D G NAEM+Y IVDGDG
Sbjct: 247 SVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDG 306
Query: 319 ADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHI 378
F IS D Q GIIT++K L FE+K SYTL++E AN + RFL+LGPF DTTTV I
Sbjct: 307 LGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKI 366
Query: 379 SVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFY 438
VEDVDEPPVF Y +EV E +G I ++A DPD +N+ +RYSIDR++D R+F
Sbjct: 367 IVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFN 426
Query: 439 VDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFY 498
+D +G + TA+ LDRE + HNITVLAME NPSQVG V I +LD+NDNAPEF Y
Sbjct: 427 IDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDY 486
Query: 499 EAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTR 558
E VCENA+ GQ+IQ +SAVD+D+P NG FY+SL +A NN NF+++DN+DNTA ILTR
Sbjct: 487 ETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTR 546
Query: 559 RSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLS 618
R+GFR+QEQSV++LPI I DSG P LSST TLTI+VC CD DG +C+ EAY+LP LS
Sbjct: 547 RNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLS 606
Query: 619 RGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAF 678
GALIAILAC+ LLVL+LLI++MRR +K+P I D+E +I ENIVRYDDEGGGEEDTEAF
Sbjct: 607 TGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAF 666
Query: 679 DIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLW 738
D+AA+ R KTR+D+ PEI+ LSR ++ N ++ +L EAD+D
Sbjct: 667 DMAAL---RNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPG 723
Query: 739 APPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
APP+DSLQTY FEG+GSVA SLSSL S +S+S+Q++D+L+DWGPRF++LA++YG +
Sbjct: 724 APPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQ 780
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 974 bits (2518), Expect = 0.0
Identities = 491/777 (63%), Positives = 596/777 (76%), Gaps = 7/777 (0%)
Query: 22 FWGLMDLTTTVLSDTPTPQGELEALLSDKP---QSHQRTKRSWVWNQFFVLEEYTGTDPL 78
F + L L + Q EL S KP RTKRSWVWNQFFVLEEY G+DPL
Sbjct: 8 FCHFLQLIALFLCFSGMSQAELSRSRS-KPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPL 66
Query: 79 YVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALD 138
YVGKLHSD+D+GDGSIKYILSGEGA +F ID+ TGDIHA +RLDREE+A YTLRAQALD
Sbjct: 67 YVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALD 126
Query: 139 RRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYG 198
R T +P+EPESEF+IKIQDINDNEPKFLDGPY A VPEMSPVGTSV+QVTATDADDPTYG
Sbjct: 127 RLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYG 186
Query: 199 NSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTT 258
NSARVVYSILQGQPYFSV+ KTGVI+TAL NMDREAK+ Y ++IQAKDM GQ GGL+GTT
Sbjct: 187 NSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTT 246
Query: 259 TVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDG 318
+V +TL+DVNDNPPRFP++ YQ +V ES P++S V R+ A D D G NAEM+Y IVDGDG
Sbjct: 247 SVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDG 306
Query: 319 ADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHI 378
F IS D Q GIIT++K L FE+K SYTL++E AN + RFL+LGPF DTTTV I
Sbjct: 307 LGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKI 366
Query: 379 SVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFY 438
VEDVDEPPVF Y +EV E +G I ++A DPD +N+ +RYSIDR++D R+F
Sbjct: 367 IVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFN 426
Query: 439 VDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFY 498
+D +G + TA+ LDRE + HNITVLAME NPSQVG V I +LD+NDNAPEF Y
Sbjct: 427 IDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDY 486
Query: 499 EAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTR 558
E VCENA+ GQ+IQ +SAVD+D+P NG FY+SL +A NN NF+++DN+DNTA ILTR
Sbjct: 487 ETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTR 546
Query: 559 RSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLS 618
R+GFR+QEQSV++LPI I DSG P LSST TLTI+VC CD DG +C+ EAY+LP LS
Sbjct: 547 RNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLS 606
Query: 619 RGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAF 678
GALIAILAC+ LLVL+LLI++MRR +K+P I D+E +I ENIVRYDDEGGGEEDTEAF
Sbjct: 607 TGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAF 666
Query: 679 DIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLW 738
D+AA+ R KTR+D+ PEI+ LSR ++ N ++ +L EAD+D
Sbjct: 667 DMAAL---RNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPG 723
Query: 739 APPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
APP+DSLQTY FEG+GSVA SLSSL S +S+S+Q++D+L+DWGPRF++LA++YG +
Sbjct: 724 APPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQ 780
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 922 bits (2382), Expect = 0.0
Identities = 458/759 (60%), Positives = 575/759 (75%), Gaps = 5/759 (0%)
Query: 34 SDTPTPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGS 93
S P + LE L + R+KRSW+WNQFF+LEEYTG+D YVGKLHSD DRGDGS
Sbjct: 29 SGFPAKKRALE-LSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGS 87
Query: 94 IKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFII 153
+KYILSG+GAG +F I++ TGDI A +RLDREE+ Y LRAQA++RRTGRP+EPESEFII
Sbjct: 88 LKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFII 147
Query: 154 KIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY 213
KI DINDNEP F Y ATVPEMS VGT V+QVTATDADDPTYGNSA+VVYSILQGQPY
Sbjct: 148 KIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPY 207
Query: 214 FSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPR 273
FSV+S+TG+I+TAL+NMDRE +E Y+V+IQAKDMGGQ+GGL+GTTTVNITL+DVNDNPPR
Sbjct: 208 FSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPR 267
Query: 274 FPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVG 333
FPQ YQ ES+P + +GR+ A D D G NAE++Y+I DG+G D FD+ TD Q G
Sbjct: 268 FPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEG 327
Query: 334 IITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGF 393
IITVKK L FE KK YTLKVE +NP++E RFL LGPF+D+ TV I VEDVDEPPVF
Sbjct: 328 IITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLA 387
Query: 394 YFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLD 453
Y +++ ED I TTI ++A+DPD N ++YS+DR +D R F +D G++ T++ LD
Sbjct: 388 YILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLD 447
Query: 454 REEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQ 513
RE WHNITV+A E+NNP Q VP+ IKVLDVNDNAPEF FYE FVCE AKA QLIQ
Sbjct: 448 RETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQ 507
Query: 514 TVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLP 573
T+ AVD+DDP +G F +SLAPEAA+ NFTI+DN+DNTA ILTR++G+ + E S + LP
Sbjct: 508 TLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLP 567
Query: 574 ILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLL 633
++I+D+ PV SSTGT+T++VC+CD G++ SC EA + P LS GAL+AIL CI +LL
Sbjct: 568 VVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILL 627
Query: 634 VLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGA 693
V V+L ++RR RK+ +I +E+I +NIV Y+DEGGGEEDT+AFDI + NP +
Sbjct: 628 VTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDN- 686
Query: 694 APKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGD 753
K R+D++PE L R P T N+ V ++ +L E D D APP+DSL TY +EG
Sbjct: 687 --KLRRDIVPEALFLPRRTP-TARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGT 743
Query: 754 GSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYG 792
GSVA SLSSL+S T+D++Q +D+L+DWGPRF+KLA++YG
Sbjct: 744 GSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADMYG 782
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 920 bits (2379), Expect = 0.0
Identities = 454/764 (59%), Positives = 584/764 (76%), Gaps = 13/764 (1%)
Query: 36 TPTPQGELEALLSDKPQSH----QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGD 91
TP PQ + L S P+S R KR W+WNQFF+LEEYTG+D YVGKLHSD D+GD
Sbjct: 29 TPVPQQRI--LSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGD 86
Query: 92 GSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEF 151
GS+KYILSG+GAG +F ID+ TGDIHA +R+DREE+A YTLRAQA++RRT RP+EPESEF
Sbjct: 87 GSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEF 146
Query: 152 IIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQ 211
+IKI DINDNEP F + Y A+VPEMS VGTSV+QVTATDADDP+YGNSARV+YSILQGQ
Sbjct: 147 VIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQ 206
Query: 212 PYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNP 271
PYFSV+ +TG+IRTAL NM+RE +E Y+V+IQAKDMGGQ+GGL+GTTTVNITL+DVNDNP
Sbjct: 207 PYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNP 266
Query: 272 PRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQ 331
PRFPQ + VLES+P+ + +G V A D D G NAE++Y I+DGDG D FDI T+ + Q
Sbjct: 267 PRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQ 326
Query: 332 VGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEP 391
GIITVKKPL +ES++ YTLKVE N H++ RF LGPF+DTT V IS+EDVDEPPVF
Sbjct: 327 EGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSR 386
Query: 392 GFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARP 451
Y EV ED+ +GT I + A+DPD ++ IR+S+DR +D R F + G+L T++P
Sbjct: 387 SSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKP 446
Query: 452 LDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQL 511
LDRE WHN+TV+A E+NNP + V V +++LDVNDNAP+F FY+ FVCENA+ GQL
Sbjct: 447 LDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQL 506
Query: 512 IQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFH 571
IQT+SAVD+DDP GQ F++SL AA NPNFT++DN+DNTARILTR++GF + E S +
Sbjct: 507 IQTISAVDKDDPLGGQKFFFSL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYL 563
Query: 572 LPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFV 631
LP++I+D+ P+ SSTGTLTI+VC+CD G++ SCS EA +LP LS GALIAIL CI +
Sbjct: 564 LPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIII 623
Query: 632 LLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQA 691
LLV+V+L +++R RK+ +I +E+I +NIV Y+DEGGGEEDT+AFDI + NP +
Sbjct: 624 LLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIE- 682
Query: 692 GAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFE 751
K R+D++PE + R P T N+ V ++ +L E D+D APP+DSL TY +E
Sbjct: 683 --EKKLRRDIIPETLFIPRRTP-TAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYE 739
Query: 752 GDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
G+ S+A SLSSL+S T++ +Q++D+L +WGPRF KLAE+YG E
Sbjct: 740 GNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGE 783
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 912 bits (2357), Expect = 0.0
Identities = 452/783 (57%), Positives = 586/783 (74%), Gaps = 8/783 (1%)
Query: 13 WLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEY 72
W+ L +Y M+ + ++S +P EL +L ++ + R+KR WVWNQ FVLEE+
Sbjct: 20 WITLPPCIYM-APMNQSQVLMSGSPL---ELNSL-GEEQRILNRSKRGWVWNQMFVLEEF 74
Query: 73 TGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTL 132
+G +P+ VG+LH+D+D G IKYILSG+GAG +F I+D TGDIHAI+RLDREE+A+YTL
Sbjct: 75 SGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTL 134
Query: 133 RAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDA 192
AQA+D T +P+EP SEFIIK+QDINDN P+FL+GPY ATVPEMS +GTSV VTATDA
Sbjct: 135 TAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDA 194
Query: 193 DDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLG 252
DDP YGNSA++VYSIL+GQPYFS++ +T +I+TAL NMDREAKE Y V+IQAKDMGG G
Sbjct: 195 DDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSG 254
Query: 253 GLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYT 312
GL+GTTT+ +TL+DVNDNPP+F Q Y SV E + + +GRV A D D G NA+ Y
Sbjct: 255 GLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYD 314
Query: 313 IVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQD 372
I+DGDG F+I++D Q GII ++KPL FE+KKSYTLKVE AN H++ RF GPF+D
Sbjct: 315 IIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKD 374
Query: 373 TTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSD 432
T TV I VED DEPPVF Y +EV E+ A+ + I ++A+DPD+T++ IR+SIDR +D
Sbjct: 375 TATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTD 434
Query: 433 PGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAP 492
R F ++ G + A PLDRE WHNIT++A E+ N SQ+ VPV IKVLDVNDNAP
Sbjct: 435 LERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAP 494
Query: 493 EFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
EF YEAF+CEN K GQ+IQTVSA+D+DDP+NG +F YSL PE NNPNFTI+ N+DN+
Sbjct: 495 EFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNS 554
Query: 553 ARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYM 612
IL + +GF +Q+Q V+ LPI+I+DSG P LSST TLTI+VC C +DG V SC+ EAY+
Sbjct: 555 LSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYV 614
Query: 613 LPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGE 672
LP+ LS GALIAILACI +LLV+V+L +++RRH+ +P II D+E++ ENI+RYDDEGGGE
Sbjct: 615 LPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGE 674
Query: 673 EDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYE 732
EDTEAFDIA + NP + G P R+D+ P+++ + R V ++ +L+E
Sbjct: 675 EDTEAFDIATLQNP-DGINGFLP--RKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHE 731
Query: 733 ADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYG 792
AD D APP+DS+Q Y +EG GSVAGSLSSL+S TSDS+Q+FD+L+DWGPRF++L ELY
Sbjct: 732 ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYS 791
Query: 793 ASE 795
E
Sbjct: 792 VGE 794
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 909 bits (2348), Expect = 0.0
Identities = 443/749 (59%), Positives = 562/749 (75%), Gaps = 4/749 (0%)
Query: 47 LSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIV 106
+ + + H R KR WVWNQFFVLEE+ G DP YVGKLHS+ D+GDGS+KYIL+GEGAG +
Sbjct: 41 IEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTI 100
Query: 107 FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFL 166
F IDDTTGDIH+ + LDRE++ Y L AQA+DRRT +P+EPESEFIIK+QDINDN PKF
Sbjct: 101 FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFT 160
Query: 167 DGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTA 226
DGPY+ TVPEMS +GTSV+QVTATDADDPTYGNSARVVYSILQGQPYFSVD KTGVIRTA
Sbjct: 161 DGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTA 220
Query: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
L NMDREA+E+Y V+IQAKDM GQ+GGL+G+TTVNITL+DVNDNPPRFPQKHYQ+ V ES
Sbjct: 221 LHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPES 280
Query: 287 APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESK 346
A + S VG++ A D D G NA+M Y+I++GDG F ISTD + GI+++KKPL++E K
Sbjct: 281 AQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKK 340
Query: 347 KSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGT 406
KSYTL +EGAN HL+ RF +LGPF+D T + I V DVDEPP+F Y +EV E+ IGT
Sbjct: 341 KSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGT 400
Query: 407 TIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLA 466
+ + A+DPD TN+ +RY I+ + + RFF +D TG + T + LDREE W+NITV A
Sbjct: 401 VVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTA 460
Query: 467 MEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNG 526
E++NP + V V I+VLDVNDN PE R Y+ VCEN+K GQ+I T+SA D+DD NG
Sbjct: 461 SEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANG 520
Query: 527 QHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSS 586
F + L NPNFT++DN+DNTA ILTRR F + Q V++LPI+I+D G P LSS
Sbjct: 521 PRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSS 580
Query: 587 TGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHR 646
+ TLTI+VC+C+ DG V +C EA++ LS GALIAIL C+ +LL +V+L +++RR +
Sbjct: 581 SSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSK 640
Query: 647 KQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIE 706
K+P II EE++ EN+V YDDEGGGEEDTEAFDI A+ NP A+ K R+D+ PE++
Sbjct: 641 KEPLII-SEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAE---ELKYRRDIRPEVK 696
Query: 707 SLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSA 766
R+ + + V ++ +L EAD+D PP+DSLQTY +EG S AGS+SSL SA
Sbjct: 697 LTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSA 756
Query: 767 TSDSEQSFDFLTDWGPRFRKLAELYGASE 795
T+ S+Q + +L DWGP F+KLAELYG E
Sbjct: 757 TTQSDQDYHYLGDWGPEFKKLAELYGEIE 785
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 890 bits (2300), Expect = 0.0
Identities = 443/745 (59%), Positives = 567/745 (76%), Gaps = 7/745 (0%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTG 114
QR+KR WVWNQFFV+EEYTG DP+ VG+LHSD+D GDG+IKYILSGEGAG +F IDD +G
Sbjct: 49 QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSG 108
Query: 115 DIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATV 174
+IHA + LDREERAQYTL AQA+DR T RP+EP SEFI+K+QDINDN P+FL Y A V
Sbjct: 109 NIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANV 168
Query: 175 PEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREA 234
PE S VGTSVIQVTA+DADDPTYGNSA++VYSIL+GQPYFSV+++TG+IRTAL NMDREA
Sbjct: 169 PERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREA 228
Query: 235 KEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVG 294
KE Y V+IQAKDMGG +GGL+GTT V ITL+DVNDNPP+FPQ YQMSV E+A VG
Sbjct: 229 KEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVG 288
Query: 295 RVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVE 354
RV AKD D G N + Y IVDGDG ++F+I+TD Q G+I +KKP+ FE+K++Y+LKVE
Sbjct: 289 RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVE 348
Query: 355 GANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAK 414
AN H++ +F++ GPF+DT TV ISVED DEPP+F Y EV E+ A GT + + AK
Sbjct: 349 AANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAK 408
Query: 415 DPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQ 474
DPD N+ IRYSIDR +D RFF ++ G + T +PLDREE +W NITV A E++N Q
Sbjct: 409 DPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQ 468
Query: 475 VGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAK----AGQLIQTVSAVDQDDPRNGQHFY 530
VPV I+VLDVNDNAP+F YE F+CE+ + + Q I T+SA D+DD NG F
Sbjct: 469 EAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFI 528
Query: 531 YSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTL 590
+SL PE +NPNFT+RDN+DNTA + RR GF +Q+Q ++ LPI+I+D G P +SST TL
Sbjct: 529 FSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTL 588
Query: 591 TIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPY 650
TI+VC CD +G ++SC+ EAY+L LS GALIAILACI +LLV+V+L +++RR +K+P
Sbjct: 589 TIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPL 648
Query: 651 IIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSR 710
I+ +EE++ ENI+ YDDEGGGEEDTEAFDIA + NP + G P R+D+ PE + + R
Sbjct: 649 IVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP-DGINGFIP--RKDIKPEYQYMPR 705
Query: 711 YVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDS 770
+ + V ++ ++ EAD D APP+DS+Q Y +EG GSVAGSLSSL+SAT+DS
Sbjct: 706 PGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDS 765
Query: 771 EQSFDFLTDWGPRFRKLAELYGASE 795
+ +D+L +WGPRF+KLA+LYG+ +
Sbjct: 766 DLDYDYLQNWGPRFKKLADLYGSKD 790
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 889 bits (2298), Expect = 0.0
Identities = 441/782 (56%), Positives = 577/782 (73%), Gaps = 11/782 (1%)
Query: 20 LYFWGLMDLT--TTVLSDTPTP---QGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTG 74
L+ W M T T +L + P ++ L D + +RTKR W+WNQFF+LEEYTG
Sbjct: 9 LFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTG 68
Query: 75 TDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRA 134
TD YVGKLH+D D+GDG++KYIL+G+GAG +F ID+ TGDIHA ++LDREE++ Y LRA
Sbjct: 69 TDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRA 128
Query: 135 QALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADD 194
+A+DR+TGR +EPESEFIIKI DINDNEPKF Y A+VPEMS VGTSVIQVTATDADD
Sbjct: 129 KAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADD 188
Query: 195 PTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGL 254
YGNSA+VVYSILQGQPYFSVD ++G+I+TAL +M RE +E Y+V+IQAKDMGGQ+GGL
Sbjct: 189 ANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGL 248
Query: 255 AGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIV 314
+GTTTVNITL+DVN+NPPRFPQ YQ + ES P+ + +GR+ A D D G NAEM+Y+I
Sbjct: 249 SGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIA 308
Query: 315 DGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTT 374
+GDGAD FD+ TD + Q GIITVK+ L FE++ YTL+V+ +N H + RFL+LGPF+DT
Sbjct: 309 EGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTA 368
Query: 375 TVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPG 434
V ISVED+DEPPVF Y +EV EDV G+ I ++A DPD NN I+YS+DR +D
Sbjct: 369 VVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMD 428
Query: 435 RFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF 494
R F + G++ T + LDRE WHNITV A E+NNP Q +PV I++LD+ND+APEF
Sbjct: 429 RIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEF 488
Query: 495 PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTAR 554
+YE FVCENAK GQLIQTVS +D+DDP G F++ PE NPNFTI DN+DNTA
Sbjct: 489 AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAG 548
Query: 555 ILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLP 614
I+TR+ G+ + + S + LPILI D+ P+ SSTGTLTI+VC+CD+ G++ SC+ EA +L
Sbjct: 549 IMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILS 608
Query: 615 VSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEED 674
LS GAL+AIL C+ +LL+LV+L +++R RK+ +I ++++ +NIV Y+DEGGGEED
Sbjct: 609 AGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEED 668
Query: 675 TEAFDIAAMWNPREAQAGAAPKTRQDMLPE-IESLSRYVPQTCAVNSTVHSYVLAKLYEA 733
T+AFDI + NP +A K R+D++PE I + R VP N V ++ +L E
Sbjct: 669 TQAFDIGTLRNP---EAREDSKLRRDVMPETIFQIRRTVP--LWENIDVQDFIHRRLKEN 723
Query: 734 DMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGA 793
D D APP+DSL TY +EG+ S+A SLSSL+S T+D Q +D+L+DWGPRF+KLA++YG
Sbjct: 724 DADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGG 783
Query: 794 SE 795
+
Sbjct: 784 DD 785
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 882 bits (2278), Expect = 0.0
Identities = 450/791 (56%), Positives = 576/791 (72%), Gaps = 16/791 (2%)
Query: 18 MSLYFWGLMD--LTTTVLSDTPTPQGELEALLSDK------PQSH-QRTKRSWVWNQFFV 68
+SL W L D L T + P PQ L + +SH QR KR WVWNQFFV
Sbjct: 7 LSLLLWVLFDGGLLTPL---QPQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFV 63
Query: 69 LEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERA 128
LEEY G++P YVGKLHSD+D+G+G++KY LSG+GAG VFTID+TTGDIHAI+ LDREE+
Sbjct: 64 LEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHAIRSLDREEKP 123
Query: 129 QYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVT 188
YTLRAQA+D T +P+EPESEFIIK+QDINDNEPKFLDGPYVATVPEMSPVG V+QV
Sbjct: 124 FYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVK 183
Query: 189 ATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMG 248
ATDADDPTYGNSARVVYSILQGQPYFS+D KTGVIRTAL NMDRE KE Y+V+IQAKDMG
Sbjct: 184 ATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMG 243
Query: 249 GQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAE 308
GQLGGLAGTT VNITL+DVNDNPPRFP+ + + V ES+PI S +GR+ A D D G NAE
Sbjct: 244 GQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNAE 303
Query: 309 MKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLG 368
++Y IV GDG + FDI TD + Q G+I +KKPL FE+KK+YT KVE +N HL+ RF + G
Sbjct: 304 IEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAG 363
Query: 369 PFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSID 428
PF+DT TV ISV DVDEPPVF Y +EV ED +GT I ++A+D DV ++++RY ID
Sbjct: 364 PFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFID 423
Query: 429 RSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVN 488
SD +F +D G + T LDRE + +N +++A +++NP V + I VLDVN
Sbjct: 424 WKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSIIASKVSNPLLTSKVNILINVLDVN 483
Query: 489 DNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDN 548
+ PE YE VCENAK GQ+IQ VSA D+D GQ F + L+PEAA PNFT+RD
Sbjct: 484 EFPPEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDF 543
Query: 549 QDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSP 608
++NTA I TRR+G+ +++Q ++ LP++I DS PV SST T+TI+VC CD DG ++SC+
Sbjct: 544 RNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNV 603
Query: 609 EAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDE 668
EA LPV LS GALIAIL CI +LL +V+L +++RR +K+ ++ +E+I +N++ YDDE
Sbjct: 604 EAIFLPVGLSTGALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSKEDIRDNVIHYDDE 663
Query: 669 GGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLA 728
GGGEEDT+AFDI A+ NP+ + K R+D+ P+ L R P N+ + ++
Sbjct: 664 GGGEEDTQAFDIGALRNPKVIEEN---KIRRDIKPDSLCLPRQRP-PMEDNTDIRDFIHQ 719
Query: 729 KLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLA 788
+L E D+D APP+DSL TY +EG GSVA SLSS+ S T++++Q +D+LTDWGPRF+ LA
Sbjct: 720 RLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLTDWGPRFKVLA 779
Query: 789 ELYGASEGPAP 799
+++G E P
Sbjct: 780 DMFGEEESYNP 790
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 832 bits (2150), Expect = 0.0
Identities = 416/781 (53%), Positives = 544/781 (69%), Gaps = 22/781 (2%)
Query: 38 TPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYI 97
TP D R KR WVWNQFFV+EEYTGT+PLYVGK+HSD D GDG+IKY
Sbjct: 41 TPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYT 100
Query: 98 LSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQD 157
+SGEGAG +F ID+ TGDIHA++RLDRE++ YTLRAQA DR T R +EPESEFIIK+QD
Sbjct: 101 ISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQD 160
Query: 158 INDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVD 217
IND+EP+FL GPY+ +V E+SP GTSV+QV A+DADDPTYG+SAR+VYS+L G+ +F+VD
Sbjct: 161 INDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVD 220
Query: 218 SKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQK 277
KTGVIRTA+ ++DRE++E YEV+IQA DM GQLGGL+G+TTV I ++DVNDNPPRFPQK
Sbjct: 221 PKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQK 280
Query: 278 HYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVD--GDGADAFDISTDPNFQVGII 335
YQ S+ ESAPI + VGRV A+D D G N +M Y + D G D F ++TD + Q II
Sbjct: 281 MYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAII 340
Query: 336 TVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYF 395
V+K L FES+ +T+ +E N ++ RF +LG F+D V ++V DVDEPP F P
Sbjct: 341 VVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGL 400
Query: 396 VEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE 455
+EV ED +G+ + +++A+DPD N +RY+IDR SD + F +D TGA++T + LDRE
Sbjct: 401 LEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRE 460
Query: 456 EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTV 515
WHNITVLAME +N +Q+ + I++LDVNDN PE YEA VCE+AK GQLIQT+
Sbjct: 461 TAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTI 520
Query: 516 SAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPIL 575
S VD+D+P+ G FY+ L PEA +NP+F++ D QDNTA + T+ GF +QEQ VF LPIL
Sbjct: 521 SVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPIL 580
Query: 576 IADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVL 635
+ DSG P LSSTGTLTI++C CD G + SC+ A+++ SLS GALIA+L C+ +L+VL
Sbjct: 581 VVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVL 640
Query: 636 VLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPRE------- 688
VLLIL++RRH K D++E++ +N+++Y+DEGGGE+DTEA+D++A+ + +
Sbjct: 641 VLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGG 700
Query: 689 ------------AQAGAAPKTRQDMLP-EIESLSRYVPQTCAVNSTVHSYVLAKLYEADM 735
G A Q LP E SL + P S ++ K+ AD
Sbjct: 701 DGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADG 760
Query: 736 DLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
DL PP+D+ QTY FEG S A SLSSL S +S SEQ F +L+ WGPRFR LA LY
Sbjct: 761 DLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHR 820
Query: 796 G 796
G
Sbjct: 821 G 821
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 762 bits (1968), Expect = 0.0
Identities = 397/749 (53%), Positives = 520/749 (69%), Gaps = 13/749 (1%)
Query: 56 RTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGD 115
RT+RSWVWNQFFV+EEY G +P+ +GKLHSD+DRG+G KY+L+GEGAG VF ID+ TG+
Sbjct: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
Query: 116 IHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVP 175
IH + LDREE+AQY L AQA+DR + RP+EP SEFIIK+QDINDN P F GPY ATVP
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 176 EMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAK 235
EMS VGTSVIQVTA DADDP+YGNSA++VY++L G P+FSVD +TGV+RTA+ NMDRE +
Sbjct: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
Query: 236 EYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGR 295
E + V+IQAKDMGG +GGL+G+TTV +TLSDVNDNPP+FPQ YQ SV+E+A + VGR
Sbjct: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
Query: 296 VFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEG 355
+ A+D D G NA M Y+I+DG+G++AF ISTD + G++TV+KPL FES++SY+ +VE
Sbjct: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
Query: 356 ANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKD 415
N ++ +L GPF+D +V ++V+D EPP F Y + VPE+ A GT + ISA D
Sbjct: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
Query: 416 PDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQV 475
D + IRYSI SDP R F + G + TA PLDRE +WHN+TVLA E+++ +Q
Sbjct: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELDSSAQA 460
Query: 476 GSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQH--FYYSL 533
V V I+ LD NDNAP+ Y+ FVC++A GQLIQ + A+D+D+ N H F L
Sbjct: 461 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPL 520
Query: 534 APEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQ 593
P+A NFT++DN+D +A +L S + + +PI + D GQP LSST T+T+
Sbjct: 521 GPDA----NFTVQDNRDGSASLLL-PSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVS 575
Query: 594 VCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIID 653
VC C DG V SC PEA++ LS GAL+AI+ C+ LL LV+L +++RR +++ ++
Sbjct: 576 VCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVL 635
Query: 654 DEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGA-APKTRQDMLPEIESLSRYV 712
+EE++ ENI+ YDDEGGGEEDTEAFDI A+ NP A A P R+D+LP +
Sbjct: 636 EEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPR 695
Query: 713 PQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSAT--SDS 770
P A V + +L EAD D PP+DS+Q Y +EG GS GSLSSL S + +
Sbjct: 696 PPGPA---DVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGA 752
Query: 771 EQSFDFLTDWGPRFRKLAELYGASEGPAP 799
+ L DWGP FR LAELYGA E PAP
Sbjct: 753 PGPAEPLDDWGPLFRTLAELYGAKEPPAP 781
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 743 bits (1919), Expect = 0.0
Identities = 397/787 (50%), Positives = 520/787 (66%), Gaps = 51/787 (6%)
Query: 56 RTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGD 115
RT+RSWVWNQFFV+EEY G +P+ +GKLHSD+DRG+G KY+L+GEGAG VF ID+ TG+
Sbjct: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
Query: 116 IHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVP 175
IH + LDREE+AQY L AQA+DR + RP+EP SEFIIK+QDINDN P F GPY ATVP
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 176 EMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAK 235
EMS VGTSVIQVTA DADDP+YGNSA++VY++L G P+FSVD +TGV+RTA+ NMDRE +
Sbjct: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
Query: 236 EYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGR 295
E + V+IQAKDMGG +GGL+G+TTV +TLSDVNDNPP+FPQ YQ SV+E+A + VGR
Sbjct: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
Query: 296 VFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEG 355
+ A+D D G NA M Y+I+DG+G++AF ISTD + G++TV+KPL FES++SY+ +VE
Sbjct: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
Query: 356 ANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKD 415
N ++ +L GPF+D +V ++V+D EPP F Y + VPE+ A GT + ISA D
Sbjct: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
Query: 416 PDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEM------ 469
D + IRYSI SDP R F + G + TA PLDRE +WHN+TVLA E+
Sbjct: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
Query: 470 --------------------------------NNPSQVGSVPVTIKVLDVNDNAPEFPRF 497
++ +Q V V I+ LD NDNAP+
Sbjct: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
Query: 498 YEAFVCENAKAGQLIQTVSAVDQDDPRNGQH--FYYSLAPEAANNPNFTIRDNQDNTARI 555
Y+ FVC++A GQLIQ + A+D+D+ N H F L P+A NFT++DN+D +A +
Sbjct: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFTVQDNRDGSASL 576
Query: 556 LTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPV 615
L S + + +PI + D GQP LSST T+T+ VC C DG V SC PEA++
Sbjct: 577 LL-PSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
Query: 616 SLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDT 675
LS GAL+AI+ C+ LL LV+L +++RR +++ ++ +EE++ ENI+ YDDEGGGEEDT
Sbjct: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
Query: 676 EAFDIAAMWNPREAQAGA-APKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEAD 734
EAFDI A+ NP A A P R+D+LP + P A V + +L EAD
Sbjct: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPGPA---DVAQLLALRLREAD 752
Query: 735 MDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSAT--SDSEQSFDFLTDWGPRFRKLAELYG 792
D PP+DS+Q Y +EG GS GSLSSL S + + + L DWGP FR LAELYG
Sbjct: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
Query: 793 ASEGPAP 799
A E PAP
Sbjct: 813 AKEPPAP 819
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 722 bits (1864), Expect = 0.0
Identities = 379/743 (51%), Positives = 508/743 (68%), Gaps = 11/743 (1%)
Query: 52 QSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDD 111
+SH R KR WVWNQFFV EE T ++G+L SD+D G+ S +Y L G GAG F ID+
Sbjct: 36 RSHLRVKRGWVWNQFFVPEEMNTTSH-HIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDE 94
Query: 112 TTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYV 171
TGDI+AIQ+LDREER+ Y LRAQ +D TGR +EPESEF+IK+ DINDNEPKFLD PY
Sbjct: 95 RTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYE 154
Query: 172 ATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMD 231
A VPEMSP GT VIQVTA+DADDP+ GN+AR++YS+LQGQPYFSV+ TGVIR + MD
Sbjct: 155 AIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGVIRIS-SKMD 213
Query: 232 REAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISS 291
RE ++ Y VIIQAKDM GQ G L+GTT+V I LSDVNDN P F + Y+++V ESAP +
Sbjct: 214 RELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGT 273
Query: 292 TVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTL 351
++G + A D D G NAEM Y+I + D + FDI T+ Q GI+ +KK + FE + Y +
Sbjct: 274 SIGTIMAYDNDIGENAEMDYSIEEDD-SQTFDIITNHETQEGIVILKKKVDFEHQNHYGI 332
Query: 352 KVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQII 411
+ + N H+ + + TT + I VEDVDEPP+F +Y EV E+ G+ + ++
Sbjct: 333 RAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVV 392
Query: 412 SAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNN 471
SA DPD + IRYSI RS + F ++ G + T+ LDRE +W+N+++ A E N
Sbjct: 393 SATDPDNRKSPIRYSITRS----KVFNIN-DNGTITTSNSLDREISAWYNLSITATEKYN 447
Query: 472 PSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYY 531
Q+ S+P+ ++VL++ND+APEF ++YE +VCENA +GQ+IQT+SAVD+D+ HFY+
Sbjct: 448 IEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRDESIEEHHFYF 507
Query: 532 SLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLT 591
+L+ E NN +FTI DNQDNTA ILT R+GF QE+ VF++ ILIAD+G P L+ST TLT
Sbjct: 508 NLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLT 567
Query: 592 IQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYI 651
I VC C D G +C + +L + +IAIL CI ++ + L L +++ RKQ
Sbjct: 568 IHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLGLKQRRKQILF 627
Query: 652 IDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRY 711
+ E+ ENI +YDDEGGGEEDTEAFDIA + R + KTR+ EI SL R
Sbjct: 628 PEKSEDFRENIFQYDDEGGGEEDTEAFDIAEL---RSSTIMRERKTRKTTSAEIRSLYRQ 684
Query: 712 VPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSE 771
Q ++ ++L KL EA+ D APPFDSLQTY FEG GS+AGSLSSL+SA SD +
Sbjct: 685 SLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLESAVSDQD 744
Query: 772 QSFDFLTDWGPRFRKLAELYGAS 794
+S+D+L + GPRF++LA ++G++
Sbjct: 745 ESYDYLNELGPRFKRLACMFGSA 767
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 549 bits (1415), Expect = e-156
Identities = 321/783 (40%), Positives = 459/783 (58%), Gaps = 35/783 (4%)
Query: 24 GLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKL 83
GL+ + + Q + +LL +H+R KR W+WNQ + EE + P +VGK+
Sbjct: 16 GLLAVAAVAAAGANPAQRDTHSLLP----THRRQKRDWIWNQMHIDEEKNTSLPHHVGKI 71
Query: 84 HSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGR 143
S + R + KY+L GE G VF +D TGD+ AI+RLDRE ++Y L A +D+ TG
Sbjct: 72 KSSVSRKNA--KYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGE 129
Query: 144 PMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARV 203
+E S F IK+ D+NDN P F + A+VPE S VGTSVI VTA DADDPT G+ A V
Sbjct: 130 NLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASV 189
Query: 204 VYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNIT 263
+Y IL+G+ YF++D+ +G I T ++DRE + YE++++A+D G L G +GT TV +T
Sbjct: 190 MYQILKGKEYFAIDN-SGRIITITKSLDREKQARYEIVVEARDAQG-LRGDSGTATVLVT 247
Query: 264 LSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFD 323
L D+NDN P F Q Y V E + ++VG +F +D DE N KY+I+ GD DAF
Sbjct: 248 LQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFT 307
Query: 324 ISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV 383
I T+P GII KPL +E + Y+ VE +P +++R+++ P + V I++ DV
Sbjct: 308 IETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMS-PPAGNRAQVIINITDV 366
Query: 384 DEPPVFEPGFYFVEVPED---VAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVD 440
DEPP+F+ FY ++ E+ IGT + A DPD +SI YSI R+SD G+FF V
Sbjct: 367 DEPPIFQQPFYHFQLKENQKKPLIGTVL----AMDPDAARHSIGYSIRRTSDKGQFFRV- 421
Query: 441 ITTGALMTARPLDREEFSWHNITVLAMEMNN----PSQVGSVPVTIKVLDVNDNAPEFPR 496
G + + LDRE + W+N+TV A E+++ + V V I+VLD NDNAPEF +
Sbjct: 422 TKKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAK 481
Query: 497 FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARIL 556
Y+ VCENA GQL+ +SA+D+D F + L E NFT+ DN DNTA I
Sbjct: 482 PYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFILNTE----NNFTLTDNHDNTANIT 537
Query: 557 TRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVS 616
+ F ++ V LP++I+D+G P + T TLT+ VC C++ G C A + VS
Sbjct: 538 VKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVS 597
Query: 617 LSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDE-ENIHENIVRYDDEGGGEEDT 675
+ A++AIL CI + V+ LLI RR RKQ IHE +V YD+EGGGE DT
Sbjct: 598 IQ--AVVAILLCILTITVITLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDT 655
Query: 676 EAFDIAAMWNPREAQAGAAP-----KTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKL 730
++D++ + + R + GA P R + +++ R+ P + + + K
Sbjct: 656 TSYDVSVLNSVR--RGGAKPPRPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKK 713
Query: 731 YEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAEL 790
EAD D PP+D+L Y +EG S+A SLSSL + +SDS+ +DFL DWGPRF+ LAEL
Sbjct: 714 DEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAEL 773
Query: 791 YGA 793
YG+
Sbjct: 774 YGS 776
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 401 bits (1030), Expect = e-111
Identities = 274/769 (35%), Positives = 408/769 (53%), Gaps = 47/769 (6%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR WV V E G P + ++ SD D D I+Y ++G GA VF+ID
Sbjct: 165 RRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSID 223
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
+G ++ + +DREE A Y LRA A+D G +E + I + D+NDN P+F++ Y
Sbjct: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMN-GNKVENPIDLYIYVIDMNDNRPEFINQVY 282
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSA---RVVYSILQ--GQPYFSVDSKTGVIRT 225
+V E S GT V+ VTA DADD T N R+V Q Q F+++S+TG I T
Sbjct: 283 NGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVT 342
Query: 226 ALMNMDREAKEYYEVIIQAKDMGGQLG-GLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284
+DRE + Y VI+QA DM G L GL+ T T IT++DVNDNPP F + V
Sbjct: 343 VAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVP 402
Query: 285 ESAPISSTVGRVFAKDLDE--GINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLS 342
E+ + + V + D D+ N Y I+ GD + F + TDP G++TV K +
Sbjct: 403 ENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVD 461
Query: 343 FESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDV 402
+E +++ L V +N + + FQ T V IS+ D++E P F + + E V
Sbjct: 462 YELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEEGV 520
Query: 403 AIGTTIQIISAKDPD-VTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHN 461
GT + SA DPD ++RYS + SDP + +++ T G + TA LDRE N
Sbjct: 521 PPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYTKN 578
Query: 462 ----ITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE-FPRFYEAFVCENAKAGQLIQTVS 516
T LA + P G+ + I ++D+NDNAPE P+ EA +CE + ++
Sbjct: 579 NVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPK--EAQICEKPNLNAI--NIT 634
Query: 517 AVDQD-DPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPIL 575
A D D DP G + + AA N+TI + A++ R E ++ +PI+
Sbjct: 635 AADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPII 691
Query: 576 IADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVL 635
+ DSG P LS+T + ++VC CDD+G C+ + L GA++AIL CI +LL +
Sbjct: 692 VTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIGAVAAAGLGTGAIVAILICILILLTM 748
Query: 636 VLL-ILSMRRHRKQPY----IIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQ 690
VLL ++ M+R K+ + +ID E+++ +NI++YD+EGGGEED + +D++ + P EA
Sbjct: 749 VLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQP-EAM 806
Query: 691 AGAAPKT----RQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQ 746
K R D P + + ++ L AD D APP+DSL
Sbjct: 807 GHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLL 866
Query: 747 TYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
+ +EG GS AGS+SSL S++S +Q +D+L DWGPRF+KLA++YG E
Sbjct: 867 VFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYGGGE 914
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 393 bits (1009), Expect = e-109
Identities = 278/805 (34%), Positives = 426/805 (52%), Gaps = 55/805 (6%)
Query: 26 MDLTTTVLSDTPTPQGELEALLSDKPQSH-----QRTKRSWVWNQFFVLEEYTGTDPLYV 80
+ L T+ ++ E+E ++ + S QR KR WV + E G P +
Sbjct: 121 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL 180
Query: 81 GKLHSDMDRGDGSIKYILSGEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQA 136
++ SD D+ + S++Y ++G GA +F I+ +G + + LDRE+ A++ LRA A
Sbjct: 181 VRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHA 239
Query: 137 LDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPT 196
+D G +E + +I + D+NDN P+FL + TVPE S GT V+ VTA DADDP
Sbjct: 240 VDIN-GNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPN 298
Query: 197 YGNSARVVYSILQGQP------YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDM-GG 249
N + Y I+ P F+++++TG I T +DRE + Y +IIQA DM G
Sbjct: 299 ALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGN 357
Query: 250 QLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEM 309
GL+ T T IT++DVNDNPP F + V E+ + V + D D+
Sbjct: 358 PTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDIIVANLTVTDKDQPHTPAW 416
Query: 310 K--YTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNL 367
Y I GD F I TDPN G++TV KP+ FE+ + + L V N + +
Sbjct: 417 NAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH 476
Query: 368 GPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPD-VTNNSIRYS 426
P Q T TV ++V DV+E P F P + E + GT + +A+DPD +IRY+
Sbjct: 477 PP-QSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYT 535
Query: 427 IDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWHNITVLAMEMNNPSQVGSVPVTI 482
+ SDP + +D G + T LDRE + + +N T LA + P G+ + I
Sbjct: 536 --KLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQI 593
Query: 483 KVLDVNDNAPE-FPRFYEAFVCENAKAGQLIQTVSAVDQD-DPRNGQH-FYYSLAPEAAN 539
+LD+NDNAP+ P+ EA CE + ++A+D D DP G F L+P
Sbjct: 594 YLLDINDNAPQVLPQ--EAETCETPDPNSI--NITALDYDIDPNAGPFAFDLPLSPVTIK 649
Query: 540 NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDD 599
N+TI + A++ + + E ++ +PI+I DSG P S+ L ++VC CD
Sbjct: 650 R-NWTITRLNGDFAQLNLK---IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDS 705
Query: 600 DGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLL-ILSMRRHRKQ----PYIIDD 654
+G C+ ++ L GA+IAIL CI +LL+LVL+ ++ M+R K+ +ID
Sbjct: 706 NG---DCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDP 762
Query: 655 EENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKT---RQDMLPEIESLSRY 711
E+++ +NI++YD+EGGGEED + +D++ + P + A R D P I + +Y
Sbjct: 763 EDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEPDAIKPVGIRRMDERP-IHAEPQY 820
Query: 712 VPQTCAVN-STVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDS 770
++ A + + ++ L AD D APP+DSL + +EG GS AGSLSSL S++S
Sbjct: 821 PVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGG 880
Query: 771 EQSFDFLTDWGPRFRKLAELYGASE 795
EQ +D+L DWGPRF+KLA++YG +
Sbjct: 881 EQDYDYLNDWGPRFKKLADMYGGGD 905
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 360 bits (924), Expect = 3e-99
Identities = 255/760 (33%), Positives = 379/760 (49%), Gaps = 43/760 (5%)
Query: 56 RTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTIDD 111
R +R+WV V E + P + ++ SD + GS+ Y + G G VF+ID
Sbjct: 42 RVRRAWVIPPISVSENHKRL-PYPLVQIKSDKQQL-GSVIYSIQGPGVDEEPRGVFSIDK 99
Query: 112 TTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYV 171
TG + LDRE+ ++ LRA ALD G +E ++ I + D NDN P FL +
Sbjct: 100 FTGKVFLNAMLDREKTDRFRLRAFALDLG-GSTLEDPTDLEIVVVDQNDNRPAFLQEAFT 158
Query: 172 ATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP-YFSVDSKTGVIRTALMNM 230
V E + GT V + ATDADDP N+A + QG P FS+D TG IRT + +
Sbjct: 159 GRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRTVQVGL 218
Query: 231 DREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPIS 290
DRE Y + +Q DM G GL T + ITL D+NDN P F + + M +E+
Sbjct: 219 DREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVS-G 275
Query: 291 STVGR--VFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKS 348
VGR V +DL N ++TI++GD F I TDP G++++ K L +ES +
Sbjct: 276 VDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEH 335
Query: 349 YTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTI 408
Y LKV N ++ L + V + V+D +EPPVF+ + E GT +
Sbjct: 336 YELKVSVQN-EAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGTLV 394
Query: 409 QIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWHNITV 464
SA+DPD T R S + DP + VD TG + T L + W+ V
Sbjct: 395 ATFSARDPD-TEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAIV 453
Query: 465 LAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPR 524
LA + + + + ++I++L+VND+AP +C G + + A D+D P
Sbjct: 454 LAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGL-LLGATDEDLPP 512
Query: 525 NGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPV 583
+G F++ L+P N+++ + AR+ R Q + + L +L+ DSGQP
Sbjct: 513 HGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRH----QVPEGLHRLSLLLRDSGQPP 568
Query: 584 LSSTGTLTIQVCSCDDDGHVMSCSPEAYML---PVSLSRGALIAILACIFVLLVLVLLIL 640
L + VC C DG C P A L LS GAL+ +LA +LLVLVLL+
Sbjct: 569 QQREQPLNVTVCRCGKDG---VCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLLVA 625
Query: 641 SMRRHRKQP----YIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPK 696
R KQ + ++++ +N++ YD++GGGEED +A+DI+ + +P P
Sbjct: 626 LRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPP 685
Query: 697 TRQDMLPEIESLSRYVPQTCAVNST----VHSYVLAKLYEADMDLWAPPFDSLQTYMFEG 752
+ P+ R PQ V T + ++ L AD D PP+D+ Y +EG
Sbjct: 686 PLRRDAPQ----GRLHPQPPRVLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEG 741
Query: 753 DGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYG 792
DGSVAG+LSS+ S+ D +Q +D+L DWGPRF +LA++YG
Sbjct: 742 DGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 353 bits (905), Expect = 5e-97
Identities = 263/781 (33%), Positives = 397/781 (50%), Gaps = 61/781 (7%)
Query: 40 QGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILS 99
Q EL + P +R KR WV E G P + ++ S+ D+ +G + Y ++
Sbjct: 136 QAELLTFPNSSP-GLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSIT 193
Query: 100 GEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKI 155
G+GA VF I+ TG + + LDRE A YTL + A+ G +E E +I +
Sbjct: 194 GQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSN-GNAVEDPMEILITV 252
Query: 156 QDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP--- 212
D NDN+P+F + +V E + GTSV++VTATDADD +A + Y+IL P
Sbjct: 253 TDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELP 312
Query: 213 ---YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVND 269
F+++ TGVI +DRE+ Y +++QA D+ G+ GL+ T T IT++D ND
Sbjct: 313 DKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTND 370
Query: 270 NPPRFPQKHYQMSVLES-APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDP 328
NPP F Y+ V E+ A + T +V D E YTI++ DG F ++T+P
Sbjct: 371 NPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNP 429
Query: 329 NFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQ-----DTTTVHISVEDV 383
GI+ K L FE+K+ Y L V N+ PF+ T TV + V DV
Sbjct: 430 VNNDGILKTAKGLDFEAKQQYILHVA---------VTNVVPFEVSLTTSTATVTVDVLDV 480
Query: 384 DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDIT 442
+E P+F P VEV ED +G I +A++PD I Y I R D + ++
Sbjct: 481 NEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPD 538
Query: 443 TGALMTARPLDREEF-----SWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF 497
TGA+ T LDRE+F S + ++A + +P G+ + + + DVNDNAP P
Sbjct: 539 TGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEP 597
Query: 498 YEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILT 557
F CE Q+I + +D D P N F L A+ N+TI+ N I+
Sbjct: 598 RTIFFCERNPKPQVI---NIIDADLPPNTSPFTAELTHGAS--ANWTIQYNDPTQESIIL 652
Query: 558 RRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSL 617
+ + +L ++ + V TL + VC C+ V +A + L
Sbjct: 653 KPKMALEVGDYKINLKLMDNQNKDQVT----TLEVSVCDCEGAAGVCR---KAQPVEAGL 705
Query: 618 SRGALIAILACIFVLLVLVLLILSMRRHR---KQPYIIDDEENIHENIVRYDDEGGGEED 674
A++ IL I LL+L+LL+L R R K+P ++ E++ +N+ YD+EGGGEED
Sbjct: 706 QIPAILGILGGILALLILILLLLLFLRRRAVVKEP-LLPPEDDTRDNVYYYDEEGGGEED 764
Query: 675 TEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEAD 734
+ FD++ + +A+ TR D+ P + S+ RY+P+ A + +++ L AD
Sbjct: 765 QD-FDLSQLHRGLDARPEV---TRNDVAPTLMSVPRYLPRP-ANPDEIGNFIDENLKAAD 819
Query: 735 MDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGAS 794
D APP+DSL + +EG GS A SLSSL S+ SD +Q +D+L +WG RF+KLA++YG
Sbjct: 820 TDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGG 879
Query: 795 E 795
E
Sbjct: 880 E 880
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 340 bits (872), Expect = 3e-93
Identities = 256/761 (33%), Positives = 384/761 (50%), Gaps = 56/761 (7%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR WV V E G P + +L S+ DR D I Y ++G GA VF ++
Sbjct: 103 RRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVE 161
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
TG + + LDREE A+Y L A+ G +E I + D ND++PKF +
Sbjct: 162 KETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDPMNISIIVTDQNDHKPKFTQDTF 220
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP------YFSVDSKTGVIR 224
+V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 221 RGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTIS 280
Query: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284
+DRE Y + IQA DM G G T + + D NDN P F + Y+ V
Sbjct: 281 VISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
Query: 285 ESAPISSTVGRVFAKDLDEGINAEMK--YTIVDGDGADAFDISTDPNFQVGIITVKKPLS 342
E+A + V R+ DLD + + Y I+ GD D F I+T P GI+T +K L
Sbjct: 339 ENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLD 397
Query: 343 FESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDV 402
FE+K +TL VE N E F+ P T T+ + VEDV+E PVF P VEV E +
Sbjct: 398 FEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGI 453
Query: 403 AIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSW--- 459
G + + +A+DPD N I Y I R DP + +D +G + LDRE+ +
Sbjct: 454 PTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQFVRN 511
Query: 460 --HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSA 517
+ + VLAM+ +P G+ + + ++DVND+ P P + +C + Q++ +
Sbjct: 512 NIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVL---NI 567
Query: 518 VDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIA 577
D+D + F L ++ + +T N++ +L+ + +Q V HL + +
Sbjct: 568 TDKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDTVVLSLKKFLKQDTYDV-HLSL--S 622
Query: 578 DSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPE---AYMLPVSLSRGALIAILACIFVLLV 634
D G + I+ CD GHV +C ++LPV L A+LA +F+LLV
Sbjct: 623 DHG----NKEQLTVIRATVCDCHGHVETCPGPWKGGFILPV------LGAVLALLFLLLV 672
Query: 635 LVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAA 694
L+LL+ R+ K+P ++ E++ +N+ Y +EGGGEED + +DI + EA+
Sbjct: 673 LLLLVRKKRKI-KEPLLLP-EDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVV 729
Query: 695 PKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDG 754
R D+ P I Y P+ A + ++++ L A+ D APP+D+L + +EG G
Sbjct: 730 --LRNDVAPTIIPTPMYRPRP-ANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSG 786
Query: 755 SVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
S A SLSSL S+ SD +Q +D+L +WG RF+KLA++YG E
Sbjct: 787 SDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGE 827
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 256 bits (653), Expect = 8e-68
Identities = 193/594 (32%), Positives = 309/594 (52%), Gaps = 39/594 (6%)
Query: 27 DLTTTVLSDTPTPQGELEALLSDKPQSH-QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHS 85
D+ V+ QG L+ + S R KRS V + + E P VGK+
Sbjct: 105 DMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKV-V 163
Query: 86 DMDRGDGSIKYILSGEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRT 141
D DR + S K+ L+G+G +F I++ TG + + LDRE A Y L + D
Sbjct: 164 DSDRPERS-KFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVN- 221
Query: 142 GRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSA 201
G+ +E + + D NDN P F +GPY+ V E SP GT+V+++TA DADDP N A
Sbjct: 222 GKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDN-A 280
Query: 202 RVVYSILQGQP------YFSVDSKTG----VIRTALMNMDREAKEYYEVIIQAKDMGGQL 251
+ Y+I Q P F +D + G V+ AL++ + YE+II+A+DM G
Sbjct: 281 LLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLD 340
Query: 252 GGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMK- 310
GL GT T I + D ND+ P+F +K +Q +V E A + + +D D+ +
Sbjct: 341 VGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGA--VGVIVNLTVEDKDDPTTGAWRA 398
Query: 311 -YTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGP 369
YTI++G+ +F+I T+P G+++V KPL +E +TL ++ N + ++ GP
Sbjct: 399 AYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP 458
Query: 370 FQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPD-VTNNSIRYSID 428
T TVHI+V DV+E PVF P V ED+++G+ + ++A DPD + + +IRYS+
Sbjct: 459 -SSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY 517
Query: 429 RSSDPGRFFYVDITTGALMTARPLDRE----EFSWHNITVLAMEMNNPSQVGSVPVTIKV 484
+ DP + ++ G + T LDRE + S + LA++ NP G+ + I +
Sbjct: 518 K--DPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITL 575
Query: 485 LDVNDNAP-EFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNF 543
DVNDNAP +P E VC++AK ++ + A D+D N F + + +A + +
Sbjct: 576 EDVNDNAPFIYPTVAE--VCDDAKNLSVV-ILGASDKDLHPNTDPFKFEIHKQAVPDKVW 632
Query: 544 TIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSC 597
I + A + S + ++ ++LPI++ DSG+P +++ L +QVCSC
Sbjct: 633 KISKINNTHALV----SLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
Score = 103 bits (258), Expect = 5e-22
Identities = 109/408 (26%), Positives = 179/408 (43%), Gaps = 35/408 (8%)
Query: 214 FSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPR 273
F ++ TG + + +DRE Y++ ++ D+ G+ L G + + + D NDN P
Sbjct: 188 FRINENTGSV-SVTRTLDREVIAVYQLFVETTDVNGKT--LEGPVPLEVIVIDQNDNRPI 244
Query: 274 FPQKHYQMSVLESAPISSTVGRVFAKDLDEGI--NAEMKYTI----VDGDGADAFDISTD 327
F + Y V+E +P +TV R+ A D D+ NA ++Y I D + F I +
Sbjct: 245 FREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPE 304
Query: 328 PNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEP 386
I+TV P + + K E +M L++G T T I ++D D
Sbjct: 305 KG---DIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVG-LTGTATATIMIDDKNDHS 360
Query: 387 PVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIR--YSIDRSSDPGRFFYV----D 440
P F + V E+ A+G + + D T + R Y+I + +PG+ F +
Sbjct: 361 PKFTKKEFQATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTII-NGNPGQSFEIHTNPQ 418
Query: 441 ITTGALMTARPLDREEFSWHNITVLAMEMN--------NPSQVGSVPVTIKVLDVNDNAP 492
G L +PLD E ++H + + + PS +V +T VLDVN+
Sbjct: 419 TNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHIT--VLDVNEGPV 476
Query: 493 EFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
+P E+ G ++ TV+A D D ++ Q YS+ + A N + +T
Sbjct: 477 FYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQH-QTIRYSVYKDPAGWLNINPINGTVDT 535
Query: 553 ARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
+L R S F + SV+ L DSG P + TGTL I + +D+
Sbjct: 536 TAVLDRESPF--VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDN 581
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 250 bits (639), Expect = 3e-66
Identities = 235/792 (29%), Positives = 373/792 (47%), Gaps = 88/792 (11%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR W + E G PL++ ++ SD + + ++ Y +SG G +F I+
Sbjct: 131 RRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIE 189
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
TG++ + +DREE + L A A G + I+++D NDN P F + Y
Sbjct: 190 RDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
V E S GT+V V ATD D+P ++ R+ YSILQ P FSV TGVI T
Sbjct: 249 NFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITTV 307
Query: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
+DRE + Y +I++ +DM GQ GL GT+T IT++D NDN P F Q Y+ V E+
Sbjct: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEEN 367
Query: 287 A-PISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES 345
A + + KDL N + +TI+ G+ F ISTD G+++V KPL++E
Sbjct: 368 AFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
Query: 346 KKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIG 405
+ L++ N R + + V + V D+DE P P +V + E++A+G
Sbjct: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
Query: 406 TTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWH 460
+ I A DP+ N N +RY + DP + +D +G+++T++ LDRE + +
Sbjct: 488 SKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
Query: 461 NITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQ 520
NITVLA++ ++ S G++ V I+ DVNDN PE + Y +C+ K G + AVD
Sbjct: 546 NITVLAIDKDDRSCTGTLAVNIE--DVNDNPPEILQEY-VVICK-PKMG--YTDILAVDP 599
Query: 521 DDPRNGQHFYYSL---APEAANNPNFTIRDNQDNTARI-LTRRSGFRQQEQSVFHLPILI 576
D+P +G FY+SL +PE + +++ D AR+ + +GF++ + +PI +
Sbjct: 600 DEPVHGAPFYFSLPNTSPEISR--LWSLTKVNDTAARLSYQKNAGFQE-----YTIPITV 652
Query: 577 AD-SGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAIL---ACIF-V 631
D +GQ ++T L + +C C H C + V L + A++AIL A +F V
Sbjct: 653 KDRAGQ---AATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAILLGIALLFSV 706
Query: 632 LLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEE---DTEAFDIAAMWNPRE 688
LL LV + + ++ P E+ +N++ + E G++ F N +
Sbjct: 707 LLTLVCGVFGATKGKRFP-----EDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQ 761
Query: 689 AQAGAAPKTRQDMLPEIESLSRYVPQTCA--------------------------VNSTV 722
G ++ E + + QT S
Sbjct: 762 GFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEW 821
Query: 723 HSYVLAKLYEA-----DMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFL 777
HS+ +L E + P D + TY +EG GS AGS+ + E DFL
Sbjct: 822 HSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGC--CSEKQEEDGLDFL 879
Query: 778 TDWGPRFRKLAE 789
+ P+F LAE
Sbjct: 880 NNLEPKFITLAE 891
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 246 bits (627), Expect = 8e-65
Identities = 206/650 (31%), Positives = 323/650 (49%), Gaps = 48/650 (7%)
Query: 50 KPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI---- 105
K + +R+KR W ++E G P +V ++ SD + + +I Y +SG G
Sbjct: 125 KDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFN 183
Query: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
+F I+ TGDI + +DRE+ Q+ L A P P IIKI+D NDN P F
Sbjct: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYF 242
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTG 221
+ TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ TG
Sbjct: 243 EHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTG 301
Query: 222 VIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQM 281
VI T +DRE + Y++I++ +DMGGQ GL T T+ I+L D NDNPP F + Y
Sbjct: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
Query: 282 SVLES-APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKP 340
V E+ + +V +DL +++ Y I+ G+ F ISTDPN G++ V KP
Sbjct: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
Query: 341 LSFESKKSYTLKVEGANPHLEMRFLNLG----PFQDTTTVHISVEDVDEPPVFEPGFYFV 396
L++E + L+V N E +F P TTTV + + D DE P P +
Sbjct: 422 LNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVI 478
Query: 397 EVPEDVAIGTTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE 455
+ + G + A DP++++ +RY + D +F ++ TG L T + LDRE
Sbjct: 479 QSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRE 536
Query: 456 ----EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQL 511
+ + +NI+V+A++ S G++ V + D ND+AP+ + E +C+N +
Sbjct: 537 SKFVKNNQYNISVVAVDAVGRSCTGTLVVHLD--DYNDHAPQIDK--EVTICQN---NED 589
Query: 512 IQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFH 571
+ VD D P NG F + L A+ N N + +D IL +R + + +
Sbjct: 590 FAVLKPVDPDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNL---DYNYYS 643
Query: 572 LPILIADSGQPVLSSTGTLTIQVCSCD--DDGHVMSCSPEAYMLPVSLSRGALIA-ILAC 628
+PI I D + L +T LT++VC C + + S V L R A++A +L
Sbjct: 644 VPIQIKD--RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGS 701
Query: 629 IFVLLVL-VLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEA 677
+ +L +L ++ +R K+ + E+ +N++ + EG GEE TEA
Sbjct: 702 VLLLCILFTCFCVTAKRTVKKCF---PEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 246 bits (627), Expect = 8e-65
Identities = 206/650 (31%), Positives = 323/650 (49%), Gaps = 48/650 (7%)
Query: 50 KPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI---- 105
K + +R+KR W ++E G P +V ++ SD + + +I Y +SG G
Sbjct: 125 KDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFN 183
Query: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
+F I+ TGDI + +DRE+ Q+ L A P P IIKI+D NDN P F
Sbjct: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYF 242
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTG 221
+ TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ TG
Sbjct: 243 EHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTG 301
Query: 222 VIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQM 281
VI T +DRE + Y++I++ +DMGGQ GL T T+ I+L D NDNPP F + Y
Sbjct: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
Query: 282 SVLES-APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKP 340
V E+ + +V +DL +++ Y I+ G+ F ISTDPN G++ V KP
Sbjct: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
Query: 341 LSFESKKSYTLKVEGANPHLEMRFLNLG----PFQDTTTVHISVEDVDEPPVFEPGFYFV 396
L++E + L+V N E +F P TTTV + + D DE P P +
Sbjct: 422 LNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVI 478
Query: 397 EVPEDVAIGTTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE 455
+ + G + A DP++++ +RY + D +F ++ TG L T + LDRE
Sbjct: 479 QSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRE 536
Query: 456 ----EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQL 511
+ + +NI+V+A++ S G++ V + D ND+AP+ + E +C+N +
Sbjct: 537 SKFVKNNQYNISVVAVDAVGRSCTGTLVVHLD--DYNDHAPQIDK--EVTICQN---NED 589
Query: 512 IQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFH 571
+ VD D P NG F + L A+ N N + +D IL +R + + +
Sbjct: 590 FAVLKPVDPDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNL---DYNYYS 643
Query: 572 LPILIADSGQPVLSSTGTLTIQVCSCD--DDGHVMSCSPEAYMLPVSLSRGALIA-ILAC 628
+PI I D + L +T LT++VC C + + S V L R A++A +L
Sbjct: 644 VPIQIKD--RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGS 701
Query: 629 IFVLLVL-VLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEA 677
+ +L +L ++ +R K+ + E+ +N++ + EG GEE TEA
Sbjct: 702 VLLLCILFTCFCVTAKRTVKKCF---PEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 244 bits (622), Expect = 3e-64
Identities = 204/642 (31%), Positives = 328/642 (51%), Gaps = 52/642 (8%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR W + E G PL++ ++ SD + + ++ Y +SG G +F I+
Sbjct: 131 RRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIE 189
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
TG++ + +DREE + L A A G + I+++D NDN P F + Y
Sbjct: 190 RDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
V E S GT+V V ATD D+P ++ R+ YSILQ P FSV TGVI T
Sbjct: 249 NFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITTV 307
Query: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
+DRE + Y +I++ +DM GQ GL GT+T IT++D NDN P F Q Y+ V E+
Sbjct: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEEN 367
Query: 287 A-PISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES 345
A + + KDL N + +TI+ G+ F ISTD G+++V KPL++E
Sbjct: 368 AFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
Query: 346 KKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIG 405
+ L++ N R + + V + V D+DE P P +V + E++A+G
Sbjct: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
Query: 406 TTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWH 460
+ I A DP+ N N +RY + DP + +D +G+++T++ LDRE + +
Sbjct: 488 SKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
Query: 461 NITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQ 520
NITVLA++ ++ S G++ V I+ DVNDN PE + Y +C+ K G + AVD
Sbjct: 546 NITVLAIDKDDRSCTGTLAVNIE--DVNDNPPEILQEY-VVICK-PKMG--YTDILAVDP 599
Query: 521 DDPRNGQHFYYSL---APEAANNPNFTIRDNQDNTARI-LTRRSGFRQQEQSVFHLPILI 576
D+P +G FY+SL +PE + +++ D AR+ + +GF++ + +PI +
Sbjct: 600 DEPVHGAPFYFSLPNTSPEISR--LWSLTKVNDTAARLSYQKNAGFQE-----YTIPITV 652
Query: 577 AD-SGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAIL---ACIF-V 631
D +GQ ++T L + +C C H C + V L + A++AIL A +F V
Sbjct: 653 KDRAGQ---AATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAILLGIALLFSV 706
Query: 632 LLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEE 673
LL LV + + ++ P E+ +N++ + E G++
Sbjct: 707 LLTLVCGVFGATKGKRFP-----EDLAQQNLIISNTEAPGDD 743
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 238 bits (606), Expect = 2e-62
Identities = 228/786 (29%), Positives = 354/786 (45%), Gaps = 71/786 (9%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR W +LE G PL++ ++ SD + + +I Y + G G +F ++
Sbjct: 131 RRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLFYVE 189
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
TG+++ + +DRE+ + + A A P P IIKI+D NDN P F + Y
Sbjct: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETY 248
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
T+ E VGT+V QV ATD D+P ++ R+ YSI+ P FS+ TGVI T
Sbjct: 249 TFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTT 307
Query: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
+DRE + Y++ I+ +DM GQ GL T+T I + DVND+ P F + Y SV E+
Sbjct: 308 SSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEEN 367
Query: 287 APISSTVGRVFA--KDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFE 344
+ + RV KDL N YTI+ G+ F I TD G++ V KPL++E
Sbjct: 368 T-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426
Query: 345 SKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAI 404
K+ L++ N R + T TV ++VED DE P P V + E+ +
Sbjct: 427 EKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEV 486
Query: 405 GTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSW 459
GTT A DP+ ++S IRY + +DP + +D TG++ R LDRE +
Sbjct: 487 GTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGI 544
Query: 460 HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVD 519
+NITVLA + + G++ + ++ DVNDN+P P+ +C+ + + AVD
Sbjct: 545 YNITVLASDQGGRTCTGTLGIILQ--DVNDNSPFIPK-KTVIICKPTMSS---AEIVAVD 598
Query: 520 QDDPRNGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIAD 578
D+P +G F +SL + + ++ D AR+ S + +PI + D
Sbjct: 599 PDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL----SYQNDPPFGSYVVPITVRD 654
Query: 579 SGQPVLSSTGTLTIQVCSC-DDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLL-VLV 636
+ +SS +L + +C C ++ P V L + A++AIL I +L +L
Sbjct: 655 --RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
Query: 637 LLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQ-----A 691
L+ KQP +I D+ IV + G ++ A AQ
Sbjct: 713 TLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTV 772
Query: 692 GAAPKTRQDMLPEIESLSRYVPQTCA-----------------------VNSTVHSYVLA 728
G+ K E+ ++C S HS+
Sbjct: 773 GSGIKNGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQP 832
Query: 729 KLYEA-----DMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPR 783
+L E + D + TY +EG GSVAGS+ + E +FL + P+
Sbjct: 833 RLGEKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGC--CSERQEEDGLEFLDNLEPK 890
Query: 784 FRKLAE 789
FR LAE
Sbjct: 891 FRTLAE 896
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 230 bits (586), Expect = 4e-60
Identities = 196/637 (30%), Positives = 311/637 (48%), Gaps = 37/637 (5%)
Query: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
+R KR W +LE G PL++ ++ SD + + +I Y + G G +F ++
Sbjct: 131 RRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLFYVE 189
Query: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
TG+++ + +DRE+ + + A A P P IIKI+D NDN P F + Y
Sbjct: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETY 248
Query: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
T+ E VGT+V QV ATD D+P ++ R+ YSI+ P FS+ TGVI T
Sbjct: 249 TFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTT 307
Query: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
+DRE + Y++ I+ +DM GQ GL T+T I + DVND+ P F + Y SV E+
Sbjct: 308 SSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEEN 367
Query: 287 APISSTVGRVFA--KDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFE 344
+ + RV KDL N YTI+ G+ F I TD G++ V KPL++E
Sbjct: 368 T-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426
Query: 345 SKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAI 404
K+ L++ N R + T TV ++VED DE P P V + E+ +
Sbjct: 427 EKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEV 486
Query: 405 GTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSW 459
GTT A DP+ ++S IRY + +DP + +D TG++ R LDRE +
Sbjct: 487 GTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGI 544
Query: 460 HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVD 519
+NITVLA + + G++ + ++ DVNDN+P P+ +C+ + + AVD
Sbjct: 545 YNITVLASDQGGRTCTGTLGIILQ--DVNDNSPFIPK-KTVIICKPTMSS---AEIVAVD 598
Query: 520 QDDPRNGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIAD 578
D+P +G F +SL + + ++ D AR+ S + +PI + D
Sbjct: 599 PDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL----SYQNDPPFGSYVVPITVRD 654
Query: 579 SGQPVLSSTGTLTIQVCSC-DDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLL-VLV 636
+ +SS +L + +C C ++ P V L + A++AIL I +L +L
Sbjct: 655 --RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
Query: 637 LLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEE 673
L+ KQP +I D + +N++ + E G++
Sbjct: 713 TLVCGASGTSKQPKVIPD-DLAQQNLIVSNTEAPGDD 748
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 224 bits (571), Expect = 2e-58
Identities = 162/513 (31%), Positives = 258/513 (50%), Gaps = 37/513 (7%)
Query: 89 RGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPE 148
R + I Y L G GA F ++ TG++ LDREE+A Y L +A D G +
Sbjct: 3053 RSNAEITYTLLGSGAE-KFKLNPDTGELKTSTPLDREEQAVYHLLVRATD---GGGRFCQ 3108
Query: 149 SEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSIL 208
+ ++ ++D+NDN P+F PY TV E + GT + +V ATDAD G + +++YS++
Sbjct: 3109 ASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADA---GLNRKILYSLI 3165
Query: 209 QGQP-YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDV 267
FS++ +G+I+ +DRE + Y + ++A D G L T TV +++ D+
Sbjct: 3166 DSADGQFSINELSGIIQLE-KPLDRELQAVYTLSLKAVDQGLPRR-LTATGTVIVSVLDI 3223
Query: 268 NDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTD 327
NDNPP F + Y +V E + + V +V+A D NAE+ Y+I+ G+ F I +
Sbjct: 3224 NDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDS- 3282
Query: 328 PNFQVGIITVKKPLSFESKKSYTLKVE---GANPHLEMRFLNLGPFQDTTTVHISVEDV- 383
+ G + + + L +ES Y L VE G P L D TV+++V D+
Sbjct: 3283 ---KTGAVFIIENLDYESSHEYYLTVEATDGGTPSLS----------DVATVNVNVTDIN 3329
Query: 384 DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDIT 442
D PVF Y + ED + ++ + A D D +NS I YSI + G F +D
Sbjct: 3330 DNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSII-DGNQGSSFTIDPV 3388
Query: 443 TGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPR-FYEAF 501
G + + LDRE S + +TV A + +P +V + V I V DVNDNAP F R Y
Sbjct: 3389 RGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVI 3448
Query: 502 VCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSG 561
+ EN G + + D+D NG F++++ + F + N +L S
Sbjct: 3449 IQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIV-TGNDEKAFEV-----NPQGVLLTSSA 3502
Query: 562 FRQQEQSVFHLPILIADSGQPVLSSTGTLTIQV 594
+++E+ + L + +AD+G+P LSS + I+V
Sbjct: 3503 IKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 204 bits (519), Expect = 3e-52
Identities = 171/573 (29%), Positives = 264/573 (46%), Gaps = 39/573 (6%)
Query: 40 QGELEALLSDKPQ--SHQRTKRSWVWNQFFVLEEY-TGTDPLYVGKLHSDMDRG-DGSIK 95
QGE+E + D +H RS + V E G+ +++ +D+D G +G +
Sbjct: 696 QGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNS--TDLDTGFNGKLV 753
Query: 96 YILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFI-IK 154
Y +SG F ID TG + + LDRE +YTL D G P + + +
Sbjct: 754 YAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYD--LGIPQKAAWRLLHVV 811
Query: 155 IQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYF 214
+ D NDN P+FL Y V E V + +IQV ATD D G + V YSI+ F
Sbjct: 812 VVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LGPNGHVTYSIVTDTDTF 868
Query: 215 SVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRF 274
S+DS TGV+ A +DRE + + + I+A+D + L T V ++L DVNDNPP F
Sbjct: 869 SIDSVTGVVNIA-RPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTF 927
Query: 275 PQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGI 334
+Y++ V E P + + + A D D G + +++Y+++D G FD+ G
Sbjct: 928 IPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLD-HGEGNFDVDK----LSGA 982
Query: 335 ITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDE---PPVFEP 391
+ + + L FE K+ Y L V + + T V + V DV+E PPVF
Sbjct: 983 VRIVQQLDFEKKQVYNLTVRAKDKGKPV------SLSSTCYVEVEVVDVNENLHPPVFSS 1036
Query: 392 GFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTAR 450
V ED +G+ + +SA D D + IRYSI S G F + TG + T+
Sbjct: 1037 FVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG-VFKIGEETGVIETSD 1095
Query: 451 PLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPR-FYEAFVCENAKAG 509
LDRE S + +TV A + + + I+V DVNDNAP+ Y + EN+
Sbjct: 1096 RLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKD 1155
Query: 510 QLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPN--FTIRDNQDNTARILTRRSGFRQQEQ 567
+ + A D D N + Y + NP F+I T I T +++Q
Sbjct: 1156 VSVVQIEAFDPDSSSNDKLMY----KITSGNPQGFFSI---HPKTGLITTTSRKLDREQQ 1208
Query: 568 SVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
L + + D+G P S+ + +++ +D+
Sbjct: 1209 DEHILEVTVTDNGSPPKSTIARVIVKILDENDN 1241
Score = 184 bits (466), Expect = 4e-46
Identities = 150/505 (29%), Positives = 244/505 (48%), Gaps = 46/505 (9%)
Query: 107 FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFI-IKIQDINDNEPKF 165
F+ID TG ++ + LDRE + +++L+ +A D+ P + + + ++D+NDN P F
Sbjct: 868 FSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTF 927
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQ-GQPYFSVDSKTGVIR 224
+ Y V E P GT ++ + +A DP G S +V YS+L G+ F VD +G +R
Sbjct: 928 IPPNYRVKVREDLPEGTVIMWL---EAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVR 984
Query: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDN--PPRFPQKHYQMS 282
+ +D E K+ Y + ++AKD G + L+ T V + + DVN+N PP F + +
Sbjct: 985 I-VQQLDFEKKQVYNLTVRAKDKGKPVS-LSSTCYVEVEVVDVNENLHPPVFSSFVEKGT 1042
Query: 283 VLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLS 342
V E AP+ S V V A D D + E++Y+I DG G F I + G+I L
Sbjct: 1043 VKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEE----TGVIETSDRLD 1098
Query: 343 FESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDE--PPVFEPGFYFVEVPE 400
ES Y L V + + P ++I VEDV++ P EP Y+ E+ E
Sbjct: 1099 RESTSHYWLTVFATDQ-------GVVPLSSFIEIYIEVEDVNDNAPQTSEP-VYYPEIME 1150
Query: 401 DVAIGTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDITTGALMT-ARPLDREEFS 458
+ ++ I A DPD ++N + Y I S +P FF + TG + T +R LDRE+
Sbjct: 1151 NSPKDVSVVQIEAFDPDSSSNDKLMYKIT-SGNPQGFFSIHPKTGLITTTSRKLDREQQD 1209
Query: 459 WHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSA 517
H + V + +P + V +K+LD NDN P+F +FY+ + E K
Sbjct: 1210 EHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKP--------- 1260
Query: 518 VDQDDPRNGQHFYYSLAPEAANNPN----FTIRDNQDNTARILTRRSGFRQQEQ-----S 568
D++ + Y+ +A + PN ++I D ++ + ++G ++
Sbjct: 1261 -DRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGE 1319
Query: 569 VFHLPILIADSGQPVLSSTGTLTIQ 593
L I D+G+P SST L I+
Sbjct: 1320 YDILSIKAVDNGRPQKSSTTRLHIE 1344
Score = 170 bits (430), Expect = 5e-42
Identities = 143/492 (29%), Positives = 223/492 (45%), Gaps = 29/492 (5%)
Query: 107 FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFL 166
FTI+ TG I+ I LD E Y L +A D TG E + I+ DINDN P F
Sbjct: 2227 FTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIV--DDINDNPPVFA 2284
Query: 167 DGPYVATVPEMSPVGTSVIQVTATDAD-DPTYGNSARVVYSILQGQPYFSVDSKTGVIRT 225
Y T+ E S +GTSV+QV ATD+D +P G S ++ + + +F VDS TG+I +
Sbjct: 2285 QQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLI-S 2343
Query: 226 ALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLE 285
L +D E + + ++A D G + L+ V + ++D+NDNPP F Q+ Y+ + E
Sbjct: 2344 LLRTLDYEQSRQHTIFVRAVD--GGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISE 2401
Query: 286 SAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES 345
AP V V A D D +++Y+I+ G+ F I + GIIT+
Sbjct: 2402 HAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDS----ATGIITLSNLHRHAL 2457
Query: 346 KKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVD-EPPVFEPGFYFVEVPEDVAI 404
K Y+L + ++ G F+ +T VH++V + P F Y VE+ E+ +
Sbjct: 2458 KPFYSLNLSVSD----------GVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPL 2507
Query: 405 GTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNIT 463
T + + D D + Y I RF+ + G + T LDRE + I+
Sbjct: 2508 HTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINE--RGQIFTLEKLDRETPAEKVIS 2565
Query: 464 VLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDD 522
V M + +V V + + D NDNAP+F YE + +A G + V A D D+
Sbjct: 2566 VRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADE 2625
Query: 523 PRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQP 582
N Y A + N I + + ++T + E F + D+G P
Sbjct: 2626 GSNADITYAIEADSESVKENLEI----NKLSGVITTKESLIGLENEFFTFFVRAVDNGSP 2681
Query: 583 VLSSTGTLTIQV 594
S + +++
Sbjct: 2682 SKESVVLVYVKI 2693
Score = 160 bits (406), Expect = 3e-39
Identities = 149/535 (27%), Positives = 251/535 (46%), Gaps = 45/535 (8%)
Query: 107 FTIDDTTGDIHAIQRLDREE-RAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
F ID TG I + L R + Y+L D ++ + + N + P F
Sbjct: 2438 FVIDSATGII-TLSNLHRHALKPFYSLNLSVSDG----VFRSSTQVHVTVIGGNLHSPAF 2492
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQ--GQPYFSVDSKTGVI 223
L Y + E +P+ T V++V TD D YG+ V Y I+ + F ++ + +
Sbjct: 2493 LQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH---VTYHIVNDFAKDRFYINERGQIF 2549
Query: 224 RTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSV 283
++ + A++ V + AKD GG++ TVN+ L+D NDN P+F Y++++
Sbjct: 2550 TLEKLDRETPAEKVISVRLMAKDAGGKVA----FCTVNVILTDDNDNAPQFRATKYEVNI 2605
Query: 284 LESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSF 343
SA ++V +V A D DEG NA++ Y I + D +++ + + N G+IT K+ L
Sbjct: 2606 GSSAAKGTSVVKVLASDADEGSNADITYAI-EAD-SESVKENLEINKLSGVITTKESLIG 2663
Query: 344 ESKKSYTLKVEGANPHLEMRFLNLGPFQDTTT-VHISVEDVD-EPPVFEPGFYFVEVPED 401
+ +T V + N P +++ V++ + + + P F FY V ED
Sbjct: 2664 LENEFFTFFVRAVD--------NGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSED 2715
Query: 402 VAIGTTIQIISAKDPDVTNNSIRYSIDRSSDP----GRFFYVDITTGALMTARPLDREEF 457
V IGT I +I A+ + ++ YS+ + + P F +D +G L + LD E
Sbjct: 2716 VPIGTEIDLIRAEH----SGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETT 2771
Query: 458 SWHNITVLA-MEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCENAKAGQLIQTV 515
W+ ++LA ++ V SV V+I+V D NDN+P F YEAF+ EN G + +
Sbjct: 2772 KWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQI 2831
Query: 516 SAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPIL 575
A D D NGQ YSL + + N + T I T + +++ + + ++
Sbjct: 2832 RASDADSGTNGQ-VMYSLDQSQSVEVIESFAINME-TGWITTLKE-LDHEKRDNYQIKVV 2888
Query: 576 IADSGQPV-LSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLS--RGALIAILA 627
+D G+ + LSST + + V +D + E Y VS +G +IAIL+
Sbjct: 2889 ASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTA--EIYKGTVSEDDPQGGVIAILS 2941
Score = 159 bits (401), Expect = 1e-38
Identities = 161/561 (28%), Positives = 247/561 (44%), Gaps = 58/561 (10%)
Query: 86 DMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQR-LDREERAQYTLRAQALDRRTGRP 144
D D + I SG G F+I TG I R LDRE++ ++ L D + P
Sbjct: 1167 DSSSNDKLMYKITSGNPQGF-FSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP-P 1224
Query: 145 MEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTS-------VIQVTATDADDPTY 197
+ I+KI D NDN+P+FL Y +PE + V ATD D+
Sbjct: 1225 KSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDE--- 1281
Query: 198 GNSARVVYSILQGQPY--FSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLA 255
G +A + YSI G + F ++ KTGV+ + + A EY + I+A D G +
Sbjct: 1282 GPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSA---AGEYDILSIKAVDNGRPQK--S 1336
Query: 256 GTTTVNI---TLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYT 312
TT ++I + + P F + + +V+ES P++ +G + E + +
Sbjct: 1337 STTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISV----EPPGIPLWFD 1392
Query: 313 IVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQD 372
I G+ FD+ G I V KPL E K +Y L VE + G
Sbjct: 1393 ITGGNYDSHFDVDKG----TGTIIVAKPLDAEQKSNYNLTVEATD----------GTTTI 1438
Query: 373 TTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSS 431
T V I V D D P F Y V +PED A T I ISA D D N I Y++ S
Sbjct: 1439 LTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLI-YTLQSSR 1497
Query: 432 DP--GRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVND 489
DP + F +D TG+L T+ LD E H +TV+ + + P + + + V D ND
Sbjct: 1498 DPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTND 1557
Query: 490 NAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRD- 547
+AP F Y+ V E+A G ++ V+A+D+D +N + Y + E+ N N + D
Sbjct: 1558 HAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLY---SIESGNIGNSFMIDP 1614
Query: 548 --NQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMS 605
TA+ L R Q+ + L + D G P +S ++ I V D+ +
Sbjct: 1615 VLGSIKTAKELDR------SNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFT 1668
Query: 606 CSPEAYMLPVSLSRGALIAIL 626
+ L ++S G+ + ++
Sbjct: 1669 SKEYSVELSETVSIGSFVGMV 1689
Score = 154 bits (390), Expect = 2e-37
Identities = 129/451 (28%), Positives = 206/451 (45%), Gaps = 39/451 (8%)
Query: 93 SIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFI 152
S+ Y + G F I+ +G I + LD E YTL Q + + + +
Sbjct: 1696 SVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAG---LSTNTTVL 1752
Query: 153 IKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQ-------VTATDADDPTYGNSARVVY 205
+ +QD NDN P F+ Y + E + + + V+ + A DAD + +A +VY
Sbjct: 1753 VHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDS---NALLVY 1809
Query: 206 SILQGQ--PYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNIT 263
I++ YF++DS TG I T L ++D E + +Q DMG V +
Sbjct: 1810 HIVEPSVHTYFAIDSSTGAIHTVL-SLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVH 1868
Query: 264 LSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFD 323
+ D+ND PP F + Y+ S+L V V A D D +++ Y+I +G+ + F
Sbjct: 1869 VIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFS 1928
Query: 324 ISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV 383
+ +++ G +TV+ S+ T++ G F T+V I+V++
Sbjct: 1929 M----DYKTGALTVQNTTQLRSRYELTVRASD------------GRFAGLTSVKINVKES 1972
Query: 384 DEPPV-FEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDIT 442
E + F Y V E+ T+ +I+A + N + Y I +P R F + T
Sbjct: 1973 KESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPI-NEPLFYHI---LNPDRRFKISRT 2028
Query: 443 TGALMTA-RPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEA 500
+G L T P DRE+ ++ V E + PS V V V + V D NDNAP F Y A
Sbjct: 2029 SGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYA 2088
Query: 501 FVCENAKAGQLIQTVSAVDQDDPRNGQHFYY 531
V + + G +I+ V+AVD+D RNG+ YY
Sbjct: 2089 VVKVDTEVGHVIRYVTAVDRDSGRNGEVHYY 2119
Score = 154 bits (389), Expect = 3e-37
Identities = 144/532 (27%), Positives = 240/532 (45%), Gaps = 40/532 (7%)
Query: 85 SDMDRG-DGSIKYILSGEGAGIV---FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRR 140
SD D G +G + Y L + V F I+ TG I ++ LD E+R Y ++ A D
Sbjct: 2834 SDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHG 2893
Query: 141 TGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNS 200
+ + + + D+ND+ P+F Y TV E P G + ++ TDAD +
Sbjct: 2894 EKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEI--N 2951
Query: 201 ARVVYSILQGQP--YFSVDSKTGVIRTALMN-MDREAKEYYEVIIQAKDMGGQLGGLAGT 257
+V Y I G P F+V++ + + +DRE ++ Y + I A D G +
Sbjct: 2952 RQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD-----GTFSSK 3006
Query: 258 TTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGD 317
V + + D NDN P + Y ++ E + ++ A D D NAE+ YT++ G
Sbjct: 3007 AIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLL-GS 3065
Query: 318 GADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVH 377
GA+ F ++ D G + PL E + Y HL +R + G ++
Sbjct: 3066 GAEKFKLNPD----TGELKTSTPLDREEQAVY---------HLLVRATDGGGRFCQASIV 3112
Query: 378 ISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGR 435
+++EDV D P F Y + V E+ GT + + A D D N I YS+ S+D
Sbjct: 3113 LTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQ- 3171
Query: 436 FFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSV-PVTIKVLDVNDNAPEF 494
F ++ +G + +PLDRE + + +++ A++ P ++ + V + VLD+NDN P F
Sbjct: 3172 -FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVF 3230
Query: 495 P-RFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTA 553
R Y A V E+ G + V A +D N + Y ++ + F+I D++
Sbjct: 3231 EYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIIS--GNEHGKFSI-DSKTGAV 3287
Query: 554 RILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMS 605
I+ + ++L + D G P LS T+ + V +D+ V S
Sbjct: 3288 FII---ENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFS 3336
Score = 152 bits (384), Expect = 1e-36
Identities = 135/509 (26%), Positives = 230/509 (45%), Gaps = 52/509 (10%)
Query: 107 FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFL 166
F +D TG I + LD E+++ Y L +A D T ++ IK+ D ND+ P+F
Sbjct: 1402 FDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTT----TILTQVFIKVIDTNDHRPQFS 1457
Query: 167 DGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP-----YFSVDSKTG 221
Y +PE + T ++Q++A D D+ +++Y++ + F +D TG
Sbjct: 1458 TSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDPLSLKKFRLDPATG 1512
Query: 222 VIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQM 281
+ T+ +D EA + + + +D + VN+ SD ND+ P F Y+
Sbjct: 1513 SLYTS-EKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNV--SDTNDHAPWFTASSYKG 1569
Query: 282 SVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPL 341
V ESA + S V +V A D D+G NAE+ Y+I G+ ++F I DP +G I K L
Sbjct: 1570 RVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMI--DP--VLGSIKTAKEL 1625
Query: 342 SFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDE-PPVFEPGFYFVEVPE 400
++ Y L V+ + P + T+V I V D P F Y VE+ E
Sbjct: 1626 DRSNQAEYDLMVKATDK-------GSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSE 1678
Query: 401 DVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWH 460
V+IG+ + +++A + +S+ Y I + + G F ++ +G ++T + LD E +
Sbjct: 1679 TVSIGSFVGMVTAH----SQSSVVYEI-KDGNTGDAFDINPHSGTIITQKALDFETLPIY 1733
Query: 461 NITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCENAKAGQLIQT----- 514
+ + M S + V + + D NDNAP F + Y + E+A ++ T
Sbjct: 1734 TLIIQGTNMAGLST--NTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVP 1791
Query: 515 --VSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHL 572
+ A D D N Y+ + P + F I D++ + +E S+FH
Sbjct: 1792 LVIRAADADKDSNALLVYHIVEPSV--HTYFAI----DSSTGAIHTVLSLDYEETSIFHF 1845
Query: 573 PILIADSGQPVLSS--TGTLTIQVCSCDD 599
+ + D G P L + +T+ V +D
Sbjct: 1846 TVQVHDMGTPRLFAEYAANVTVHVIDIND 1874
Score = 119 bits (297), Expect = 1e-26
Identities = 145/558 (25%), Positives = 231/558 (41%), Gaps = 53/558 (9%)
Query: 86 DMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRP 144
D D+G + + Y + G F ID G I + LDR +A+Y L +A D+ G P
Sbjct: 1588 DKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDK--GSP 1645
Query: 145 MEPESEFIIKIQDINDN-EPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARV 203
E + I DN PKF Y + E +G+ V VTA + + V
Sbjct: 1646 PMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTA--------HSQSSV 1697
Query: 204 VYSILQGQ--PYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVN 261
VY I G F ++ +G I T +D E Y +IIQ G + GL+ TTV
Sbjct: 1698 VYEIKDGNTGDAFDINPHSGTIITQ-KALDFETLPIYTLIIQ----GTNMAGLSTNTTVL 1752
Query: 262 ITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGR-------VFAKDLDEGINAEMKYTIV 314
+ L D NDN P F Q Y + ESA I+S V + A D D+ NA + Y IV
Sbjct: 1753 VHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIV 1812
Query: 315 DGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTT 374
+ F I + G I L +E + V+ + F +
Sbjct: 1813 EPSVHTYFAIDS----STGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLF---AEYAANV 1865
Query: 375 TVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN-NSIRYSIDRSSDP 433
TVH+ ++ D PPVF Y + G + ++A D D + + + YSI +
Sbjct: 1866 TVHV-IDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSI-TEGNI 1923
Query: 434 GRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE 493
G F +D TGAL S + +TV A ++ G V I V + ++ +
Sbjct: 1924 GEKFSMDYKTGALTVQNTTQLR--SRYELTVRA---SDGRFAGLTSVKINVKESKESHLK 1978
Query: 494 FPR-FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
F + Y A V EN+ + + ++A+ +P N FY+ L P+ R T
Sbjct: 1979 FTQDVYSAVVKENSTEAETLAVITAI--GNPINEPLFYHILNPDR--------RFKISRT 2028
Query: 553 ARIL-TRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAY 611
+ +L T + F +++Q F + + + + +P + + + V +D+ V P
Sbjct: 2029 SGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYA 2088
Query: 612 MLPVSLSRGALIAILACI 629
++ V G +I + +
Sbjct: 2089 VVKVDTEVGHVIRYVTAV 2106
Score = 117 bits (294), Expect = 3e-26
Identities = 131/540 (24%), Positives = 220/540 (40%), Gaps = 49/540 (9%)
Query: 68 VLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREER 127
+L Y G + V +D I I G G F++D TG + +Q + R
Sbjct: 1889 LLPTYKGVKVITVNATDADSSAFSQLIYSITEGN-IGEKFSMDYKTGAL-TVQNTT-QLR 1945
Query: 128 AQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQV 187
++Y L +A D R + I +++ ++ KF Y A V E S ++ +
Sbjct: 1946 SRYELTVRASDGRFAGLTSVK----INVKESKESHLKFTQDVYSAVVKENSTEAETLAVI 2001
Query: 188 TA--TDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAK 245
TA ++P + Y IL F + +GV+ T DRE +E ++V+++
Sbjct: 2002 TAIGNPINEPLF-------YHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVT 2054
Query: 246 DMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGI 305
+ V + + D NDN P F Y V + + V A D D G
Sbjct: 2055 EE--HKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGR 2112
Query: 306 NAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES-KKSYTLKV---EGANPHLE 361
N E+ Y + + + F I +G I++KK ++ K Y + V +G NP
Sbjct: 2113 NGEVHYYLKEHH--EHFQIGP-----LGEISLKKQFELDTLNKEYLVTVVAKDGGNP--- 2162
Query: 362 MRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNN 421
F V I+V + PVFE FY E+ E + + + + + A P+
Sbjct: 2163 -------AFSAEVIVPITVMN-KAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPE--GL 2212
Query: 422 SIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVT 481
+ YSI DP F ++ TG + PLD E + +++ A + + V V
Sbjct: 2213 KVFYSI-TDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAH-AEVFVD 2270
Query: 482 IKVLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN 540
I V D+NDN P F + Y + E + G + V A D D N Y + ++
Sbjct: 2271 IIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSH 2330
Query: 541 PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
+F + D+ +L + ++ ++F + D G P LSS +T+ V +D+
Sbjct: 2331 DHFHV-DSSTGLISLLRTLDYEQSRQHTIF---VRAVDGGMPTLSSDVIVTVDVTDLNDN 2386
Score = 115 bits (287), Expect = 2e-25
Identities = 116/431 (26%), Positives = 188/431 (43%), Gaps = 53/431 (12%)
Query: 122 LDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVG 181
L+RE + YTL +AL++ T +E ++ +++ D ND P F Y ++PE + +
Sbjct: 108 LNREVKDHYTLIVKALEKNTN--VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIR 165
Query: 182 TSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVI 241
TS+ +V+ATDAD G + YS F++ +GVI +D + YE+
Sbjct: 166 TSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTGRLDYLETKLYEME 221
Query: 242 IQAKDMGGQLGGLAGTTT---VNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFA 298
I A D G +L G +G ++ + + + N+ P S L+ P + V
Sbjct: 222 ILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAI---VTV 278
Query: 299 KDLDEGINAEM-KYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGA- 356
D D+G N ++ +IV GD F TV+ SF K Y +K G
Sbjct: 279 DDCDQGANGDIASLSIVAGDLLQQFR------------TVR---SFPGSKEYKVKAIGGI 323
Query: 357 ---------NPHLEMRFLNLGP-FQDTTTVHISVEDVDEPPV-FEPGFYFVEVPEDVAIG 405
N L+ + P F +H++ PV FE Y E+ E
Sbjct: 324 DWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPN 383
Query: 406 TTIQIISAKDPDVTNNSIRYSIDRSSDPGRF-FYVDITTGALMTARPLDREEFSWHNITV 464
T + ++ A + +RY S PG+ F ++ TG + P+ R++ +
Sbjct: 384 TPVVMVKAIP---AYSHLRYVF--KSTPGKAKFSLNYNTGLISILEPVKRQQAAH----- 433
Query: 465 LAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPR-FYEAFVCENAKAGQLIQTVSAVDQDDP 523
+E+ + S V +KVL N N PEF + Y+A EN G + ++SAVD D+
Sbjct: 434 FELEVTTSDRKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEG 493
Query: 524 RNGQHFYYSLA 534
NG + YS+A
Sbjct: 494 ENG-YVTYSIA 503
Score = 85.9 bits (211), Expect = 1e-16
Identities = 105/415 (25%), Positives = 181/415 (43%), Gaps = 51/415 (12%)
Query: 76 DPLYVGKLHSDMDRG---DGSIKYILSGEGAGIVFTIDDTTGD----IHAIQRLDREERA 128
DP Y D D+G D + I++G+ T+ G + AI +D +
Sbjct: 270 DPAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHP 329
Query: 129 -QYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGP-------YVATVPEMSPV 180
Y L QA D+ G P + S +I + P+F GP Y A + E +P
Sbjct: 330 FGYNLTLQAKDK--GTPPQFSSVKVIHV-----TSPQFKAGPVKFEKDVYRAEISEFAPP 382
Query: 181 GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV 240
T V+ V A P Y + R V+ G+ FS++ TG+I + L + R+ ++E+
Sbjct: 383 NTPVVMVKAI----PAYSH-LRYVFKSTPGKAKFSLNYNTGLI-SILEPVKRQQAAHFEL 436
Query: 241 IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD 300
+ D +T V + + N NPP F Q Y+ + E+ PI +TV + A D
Sbjct: 437 EVTTSDR-------KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVD 489
Query: 301 LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFE-SKKSYTLKVEGANPH 359
DEG N + Y+I A+ + + G ++ + L +E + YTL++ ++
Sbjct: 490 PDEGENGYVTYSI-----ANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWG 544
Query: 360 LEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVT 419
L R + T+ ++ + D P+FE +P D+ +G I +SA D D
Sbjct: 545 LPYR----REVEVLATITLNNLN-DNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADEL 599
Query: 420 NNSIRYSIDRSSDPGRFFYVDITTGALMTARPLD---REEFSWHNITVLAMEMNN 471
++Y I+ ++ FF ++ +G L R L + S+H++ + A + N
Sbjct: 600 -QLVQYQIEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGEN 652
Score = 84.0 bits (206), Expect = 5e-16
Identities = 110/437 (25%), Positives = 184/437 (42%), Gaps = 52/437 (11%)
Query: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRT----GRPMEPESEFIIKIQDINDN 161
+F I T+G I RLD E Y + A DR + ++ + I+ N+
Sbjct: 194 MFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANEC 253
Query: 162 EPKFLDGPYVATVPEMSPV----GTSVIQVTATDADDPTYGNSARVVYSILQG---QPYF 214
P V T +SP + VT D D G+ A + SI+ G Q +
Sbjct: 254 AP-------VITAVTLSPSELDRDPAYAIVTVDDCDQGANGDIASL--SIVAGDLLQQFR 304
Query: 215 SVDSKTGVIR---TALMNMDREAKEY-YEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDN 270
+V S G A+ +D ++ + Y + +QAKD G + +++T
Sbjct: 305 TVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTP-PQFSSVKVIHVTSPQFKAG 363
Query: 271 PPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNF 330
P +F + Y+ + E AP ++ V V A + ++Y G F + N+
Sbjct: 364 PVKFEKDVYRAEISEFAPPNTPVVMVKAIP----AYSHLRYVFKSTPGKAKFSL----NY 415
Query: 331 QVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVD-EPPVF 389
G+I++ +P+ + + L+V ++ + +T V + V + PP F
Sbjct: 416 NTGLISILEPVKRQQAAHFELEVTTSDR------------KASTKVLVKVLGANSNPPEF 463
Query: 390 EPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDITTGALMT 448
Y E+V IGTT+ +SA DPD N + YSI + F +D TGA+ T
Sbjct: 464 TQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVP--FAIDHFTGAVST 521
Query: 449 ARPLDREEF-SWHNITVLAMEMNNP-SQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCEN 505
+ LD E + + + A + P + V TI + ++NDN P F + E + +
Sbjct: 522 SENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRD 581
Query: 506 AKAGQLIQTVSAVDQDD 522
G+ I TVSA+D D+
Sbjct: 582 LGVGEQITTVSAIDADE 598
Score = 58.9 bits (141), Expect = 2e-08
Identities = 65/265 (24%), Positives = 109/265 (41%), Gaps = 26/265 (9%)
Query: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284
TA++N RE K++Y +I++A + + T V + + D ND P F Y +S+
Sbjct: 105 TAILN--REVKDHYTLIVKALEKNTNV---EARTKVRVQVLDTNDLRPLFSPTSYSVSLP 159
Query: 285 ESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFE 344
E+ I +++ RV A D D G N E Y+ D D F I G+I + L +
Sbjct: 160 ENTAIRTSIARVSATDADIGTNGEFYYSF--KDRTDMFAIHPTS----GVIVLTGRLDYL 213
Query: 345 SKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPED--V 402
K Y +++ A+ +++ + TVHI + P + E+ D
Sbjct: 214 ETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAY 273
Query: 403 AIGTTIQIISAKDPDVTNNSI-------RYSIDRSSDPGRFFYVDITTGALMTARPLDRE 455
AI T + D+ + SI ++ RS + + V G + P
Sbjct: 274 AIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFG-- 331
Query: 456 EFSWHNITVLAMEMNNPSQVGSVPV 480
+N+T+ A + P Q SV V
Sbjct: 332 ----YNLTLQAKDKGTPPQFSSVKV 352
Score = 49.3 bits (116), Expect = 1e-05
Identities = 56/199 (28%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 434 GRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE 493
G F ++ I T TA L+RE + + V A+E N + + V ++VLD ND P
Sbjct: 91 GDFCFLRIRTKGGNTAI-LNREVKDHYTLIVKALEKNTNVEART-KVRVQVLDTNDLRPL 148
Query: 494 F-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
F P Y + EN I VSA D D NG+ FYYS F I T
Sbjct: 149 FSPTSYSVSLPENTAIRTSIARVSATDADIGTNGE-FYYSFKDRT---DMFAIHP----T 200
Query: 553 ARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTG-----TLTIQVCSCDDDGHVMSCS 607
+ ++ E ++ + IL AD G + S+G LT+ + ++ V++
Sbjct: 201 SGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITA- 259
Query: 608 PEAYMLPVSLSRGALIAIL 626
+ P L R AI+
Sbjct: 260 --VTLSPSELDRDPAYAIV 276
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 224 bits (571), Expect = 2e-58
Identities = 166/517 (32%), Positives = 253/517 (48%), Gaps = 34/517 (6%)
Query: 91 DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALD----RRTGRPME 146
+G IKY +S +F I+ +TG + + LD E ++ + A+D RTG
Sbjct: 3121 NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGY--- 3177
Query: 147 PESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYS 206
+ + D+NDN P FL Y TV E +P GT+VI + ATDAD G +A + Y+
Sbjct: 3178 --CSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADS---GTNAVIAYT 3232
Query: 207 ILQGQP-YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLS 265
+ F +D TGVI T +D E K+ Y + ++A ++ + TVNI L
Sbjct: 3233 VQSSDSDLFVIDPNTGVITTQGF-LDFETKQSYHLTVKAFNVPDE--ERCSFATVNIQLK 3289
Query: 266 DVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDIS 325
N+ PRF K Y + E+AP + VG VFA D D G + E+ Y I F I
Sbjct: 3290 GTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI- 3348
Query: 326 TDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNL-GPFQDTTTVHISVEDVD 384
N + G I V L E ++ +LKV L F ++ G D TV+++V D +
Sbjct: 3349 ---NKKTGQIYVSGILDREKEERVSLKV------LAKNFGSIRGADIDEVTVNVTVLDAN 3399
Query: 385 EPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYS-IDRSSDPGRFFYVDITT 443
+PP+F Y V++ E V IGT + +SA D D + R+S S + F ++ T
Sbjct: 3400 DPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQT 3459
Query: 444 GALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVC 503
G + LDRE +N++VLA++ PS GS + + + D+NDN P E V
Sbjct: 3460 GQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPML-TVSEGEVM 3518
Query: 504 ENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFR 563
EN + G L+ T+ + D D P N F Y L F++ +TA +L+
Sbjct: 3519 ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSL-----STAGVLSTTREID 3573
Query: 564 QQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
+++ + F+L ++ DSG P +SSTGT+ I V +D+
Sbjct: 3574 REQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN 3610
Score = 211 bits (536), Expect = 3e-54
Identities = 173/543 (31%), Positives = 274/543 (50%), Gaps = 45/543 (8%)
Query: 85 SDMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGR 143
+D D G + I+Y L EG F +D TG I + LD E R QY+L QA+DR G
Sbjct: 275 ADADEGTNADIRYRLQDEGTP--FQMDPETGLITVREPLDFEARRQYSLTVQAMDR--GV 330
Query: 144 P-MEPESEFIIKIQDINDNEP--KFLDGPYV---ATVPEMSPVGTSVIQVTATDADDPTY 197
P + +E +I++ D+NDN+P KF P A+V E + VGT V +T TDAD P
Sbjct: 331 PSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
Query: 198 GNSARVVYSILQG--QPYFSVDSKT----GVIRTALMNMDREAKEYYEVIIQAKDMGGQL 251
+ V IL G Q +F V S +I+ A +DRE Y + + D G
Sbjct: 391 NGNISV--QILGGNEQRHFEVQSSKVPNLSLIKVASA-LDRERIPSYNLTVSVSDNYGAP 447
Query: 252 GGLA-----GTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGIN 306
G A ++ I ++D+ND+PP F Q+ Y++++ E AP S V + A D D G+N
Sbjct: 448 PGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLN 507
Query: 307 AEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLN 366
A ++Y+IV G+G F IS G++T + + + + + ++ R
Sbjct: 508 ANLRYSIVSGNGLGWFHISEHS----GLVTTGSSGGLDRELASQIVL-----NISARDQG 558
Query: 367 LGPFQDTTTVHISVEDV-DEPPVF-EPGFYFVEVPEDVAIGTTIQIISAKDPDVTNN-SI 423
+ P + +++ DV DE PVF +P Y V V E+ GT + ++ A D D+ +N ++
Sbjct: 559 VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV 618
Query: 424 RYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIK 483
R+S+ + R F +D +G L T LDREE +++++ VLA ++ +P Q + +
Sbjct: 619 RFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVS 678
Query: 484 VLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPN 542
+LD+NDN+P F P Y A + EN G I TVSA D D NG YS++ A +
Sbjct: 679 LLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGT-VKYSIS--AGDRSR 735
Query: 543 FTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGH 602
F + + + +++ R ++E++ + L I+ D G + +TI V D+
Sbjct: 736 FQV----NAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPP 791
Query: 603 VMS 605
V S
Sbjct: 792 VFS 794
Score = 211 bits (536), Expect = 3e-54
Identities = 170/553 (30%), Positives = 256/553 (46%), Gaps = 33/553 (5%)
Query: 69 LEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERA 128
+EE G + D D G ++ GA F ID +GD+ A +RLDRE R+
Sbjct: 1749 VEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRS 1808
Query: 129 QYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVT 188
+Y+L +A D M I + D+ND+ PKF Y +PE + G+ V +
Sbjct: 1809 KYSLLVRADDGLQSSDMRIN----ITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAIL 1864
Query: 189 ATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMG 248
ATD D G +V + +F ++ TGV + +D E ++YY + ++A+D G
Sbjct: 1865 ATDDDSGVNGEITYIVNEDDEDGIFF-LNPITGVFNLTRL-LDYEVQQYYILTVRAEDGG 1922
Query: 249 GQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAE 308
GQ T V + DVNDNPP F Y S++E+ P+ STV D D+GIN++
Sbjct: 1923 GQFT----TIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQ 1978
Query: 309 MKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLG 368
+ Y+I GD F + + G++ V K L ES+ Y L V+ ++ +
Sbjct: 1979 LTYSIASGDSLGQFTVDKN-----GVLKVLKALDRESQSFYNLVVQVH----DLPQIPAS 2029
Query: 369 PFQDTTTVHISVEDV-DEPPVF-EPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS-IRY 425
F T V I + DV D PP F P + +PE+ I T + A DPD NS I Y
Sbjct: 2030 RFTSTAQVSIILLDVNDNPPTFLSPKLTY--IPENTPIDTVVFKAQATDPDSGPNSYIEY 2087
Query: 426 SIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVL 485
++ + G F + G + LDREE S + +TV+A + PS S V + VL
Sbjct: 2088 TL--LNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVL 2145
Query: 486 DVNDNAPEFPR-FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFT 544
D+NDN P F + Y+ + EN G I V A D D+ NGQ Y + N F
Sbjct: 2146 DINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIV--NGNTNQEFR 2203
Query: 545 IRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVM 604
I D+ +T +++ +HL + D G + T T++I + +D V
Sbjct: 2204 I----DSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVF 2259
Query: 605 SCSPEAYMLPVSL 617
SP + +P +L
Sbjct: 2260 ELSPYSVNVPENL 2272
Score = 186 bits (471), Expect = 1e-46
Identities = 163/531 (30%), Positives = 257/531 (48%), Gaps = 47/531 (8%)
Query: 85 SDMDRG-DGSIKY-ILSGEGAGIVFTIDDTTGDIHAIQR--LDREERAQYTLRAQALDRR 140
+D D G + +++Y I+SG G G F I + +G + LDRE +Q L A D+
Sbjct: 500 TDGDSGLNANLRYSIVSGNGLGW-FHISEHSGLVTTGSSGGLDRELASQIVLNISARDQG 558
Query: 141 TGRPMEPESEFIIKIQDINDNEPKFLDGP-YVATVPEMSPVGTSVIQVTATDADDPTYGN 199
P ++ ++ + D+ND +P F Y +V E +P GT ++ + ATD D G+
Sbjct: 559 V-HPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGD---LGD 614
Query: 200 SARVVYSILQGQP---YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAG 256
+ V +S+ + + F +D +G + T + ++DRE + +Y +++ A D+G +
Sbjct: 615 NGTVRFSLQEAETDRRSFRLDPVSGRLST-ISSLDREEQAFYSLLVLATDLGSP--PQSS 671
Query: 257 TTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDG 316
+N++L D+NDN P F Y + E+ P S + V A D D G N +KY+I G
Sbjct: 672 MARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAG 731
Query: 317 DGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKV---EGANPHLEMRFLNLGPFQDT 373
D + F + N Q G+I+ + L E K +Y L++ +G N P Q
Sbjct: 732 DRS-RFQV----NAQSGVISTRMALDREEKTAYQLQIVATDGGNLQ--------SPNQAI 778
Query: 374 TTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDP 433
T+ + ++ D PPVF Y V E+VA+G + +SA D+ N++I Y I
Sbjct: 779 VTITV-LDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL-NSNISYLITTGDQK 836
Query: 434 GRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE 493
G F ++ TG L TA +DREE S++ + V+A + + G V I V D+NDN+P
Sbjct: 837 G-MFAINQVTGQLTTANVIDREEQSFYQLKVVA---SGGTVTGDTMVNITVKDLNDNSPH 892
Query: 494 FPRFYEAF-VCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
F + E+ V EN +AG I AVD D+ NG Y NP N+ N
Sbjct: 893 FLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY-----SLKQNPKNLFAINEKNG 947
Query: 553 ARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHV 603
L G + + IL +D G P LSS+ LT+ V +D+ V
Sbjct: 948 TISLL---GPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPV 995
Score = 182 bits (462), Expect = 1e-45
Identities = 156/533 (29%), Positives = 252/533 (47%), Gaps = 43/533 (8%)
Query: 79 YVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALD 138
+VG + + + +I Y+++ +F I+ TG + +DREE++ Y L+ A
Sbjct: 811 HVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA-- 868
Query: 139 RRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYG 198
+G + ++ I ++D+NDN P FL V E G S+ Q A D D+ G
Sbjct: 869 --SGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDE---G 923
Query: 199 NSARVVYSILQG-QPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGT 257
+ V+YS+ Q + F+++ K G I + L +D A Y ++ I A DMG + L+ +
Sbjct: 924 VNGMVLYSLKQNPKNLFAINEKNGTI-SLLGPLDVHAGSY-QIEILASDMG--VPQLSSS 979
Query: 258 TTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGD 317
+ + + DVNDN P F Q Y++++ ES P++S +V A D D G N E+ YTI +G+
Sbjct: 980 VILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGN 1039
Query: 318 GADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVH 377
DAF I D G + +K L E + Y L V ++ +E P T V
Sbjct: 1040 TGDAFGIFPD-----GQLYIKSELDRELQDRYVLMVVASDRAVE-------PLSATVNVT 1087
Query: 378 ISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGR 435
+ +EDV D P+F Y E+ G+ + +SA D D N +RYS +
Sbjct: 1088 VILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD-- 1145
Query: 436 FFYVDITTGALMTARPLDREEF------SWHNITVLAMEMNNPSQV-GSVPVTIKVLDVN 488
F + +G + DRE + + TV+A + P + V + + D+N
Sbjct: 1146 -FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDIN 1204
Query: 489 DNAPEFPR-FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRD 547
DNAP+F + FY+A + E+A + VSA D D+ NG +YS+ + F I
Sbjct: 1205 DNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGL-IHYSII-KGNEERQFAI-- 1260
Query: 548 NQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
D+T+ +T + + L I DSG L+ST TL I + +D+
Sbjct: 1261 --DSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDN 1311
Score = 178 bits (452), Expect = 2e-44
Identities = 158/549 (28%), Positives = 251/549 (45%), Gaps = 49/549 (8%)
Query: 89 RGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPE 148
RG+ YI SG G F ID TG + Q LD E+ +Y + +A D P
Sbjct: 2595 RGEPMSYYIASGN-LGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP-PFSSY 2652
Query: 149 SEFIIKIQDINDNEPKFLDGPYVATVPE-MSPVGTSVIQVTATDADDPTYGNSARVVYSI 207
+ I + D+NDN P F + P+++ + E +SP ++ V+A D D G + ++ Y I
Sbjct: 2653 EKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTVSAMDKDS---GPNGQLDYEI 2707
Query: 208 LQG--QPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLS 265
+ G + FS++ TG IR+ + +DRE +Y + I++ D G + +NI
Sbjct: 2708 VNGNMENSFSINHATGEIRS-VRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINIL-- 2764
Query: 266 DVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDIS 325
D NDN PRF Q + V E++P+ TV RV D D GINA +Y+I+D + S
Sbjct: 2765 DENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPS 2823
Query: 326 TDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-D 384
T G I + +PL+ E Y ++V + + +T V I V D+ D
Sbjct: 2824 T------GDIVISRPLNREDTDRYRIRVSAHD----------SGWTVSTDVTIFVTDIND 2867
Query: 385 EPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITT 443
P F Y+++ PE IG+ + + A DPD +N + Y I S+ +F ++ TT
Sbjct: 2868 NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE---YFRINATT 2924
Query: 444 GALMTARPLDRE--------EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFP 495
G + + L + + H+ V + + PS + VTI ++D NDNAP+F
Sbjct: 2925 GEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFL 2984
Query: 496 RF-YEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTAR 554
+ Y V +N K G + V+A+D D Y + +N N + DN
Sbjct: 2985 KSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFI-----SNDNHLGKFKLDNDTG 3039
Query: 555 ILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLP 614
++ S F + + D G P LSS T+ I V + S S + +P
Sbjct: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
Query: 615 VSLSRGALI 623
S S G+++
Sbjct: 3100 ESHSIGSIV 3108
Score = 177 bits (449), Expect = 3e-44
Identities = 150/524 (28%), Positives = 248/524 (47%), Gaps = 46/524 (8%)
Query: 85 SDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRP 144
SD D G +I S A + FTI+ +TGDI + L+RE+ +Y +R A D
Sbjct: 2797 SDEDIGINAISRY-SIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---- 2851
Query: 145 MEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVV 204
++ I + DINDN P+F Y PE++ +G+ V QV ATD D+ G++ +V
Sbjct: 2852 WTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDE---GSNGQVF 2908
Query: 205 YSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV-------IIQAKDMGGQLGGLAGT 257
Y I YF +++ TG I + + + V I+ + D G L
Sbjct: 2909 YFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKP--SLISE 2966
Query: 258 TTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFA-KDLDEGINAEMKYTIVDG 316
TTV I + D NDN P+F + Y V ++ + + + RV A D D G+N+E++Y I +
Sbjct: 2967 TTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISND 3026
Query: 317 DGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKV---EGANPHLEMRFLNLGPFQDT 373
+ F + D G I+V L + +++ + V + NP P
Sbjct: 3027 NHLGKFKLDND----TGWISVASSLISDLNQNFFITVTAKDKGNP----------PLSSQ 3072
Query: 374 TTVHISV-EDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS-IRYSIDRSS 431
TVHI+V E+ P F +PE +IG+ ++ +SA+D D N I+YSI +
Sbjct: 3073 ATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGN 3132
Query: 432 DPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNA 491
+ G F ++ +TG L A+ LD E H +T+ A++ ++ G VT+ V+DVNDN+
Sbjct: 3133 EEG-IFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNS 3191
Query: 492 PEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQD 550
P F Y V ENA +G + ++A D D +G + + +++++ F I D
Sbjct: 3192 PVFLSDDYFPTVLENAPSGTTVIHLNATDAD---SGTNAVIAYTVQSSDSDLFVI----D 3244
Query: 551 NTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQV 594
++T + + + +HL + + S T+ IQ+
Sbjct: 3245 PNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
Score = 176 bits (445), Expect = 1e-43
Identities = 156/554 (28%), Positives = 256/554 (46%), Gaps = 51/554 (9%)
Query: 85 SDMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGR 143
SD D G +G I Y ++ G F I G ++ LDRE + +Y L A DR
Sbjct: 1021 SDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAV-E 1078
Query: 144 PMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARV 203
P+ + ++D+NDN P F Y E G+ V +V+A D D +G + V
Sbjct: 1079 PLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKD---FGPNGEV 1135
Query: 204 VYSILQGQPYFSVDSKTGVIRTALMNMDREA------KEYYEVIIQAKDMGGQLGGLAGT 257
YS QP F + + +G I T DRE+ + + A D G L
Sbjct: 1136 RYSFEMVQPDFELHAISGEI-TNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQP-LKDQ 1193
Query: 258 TTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGD 317
TV++ + D+NDN P+F + YQ ++ ESA + V RV A D+DEG N + Y+I+ G+
Sbjct: 1194 ATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGN 1253
Query: 318 GADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVH 377
F I + G +T+ L +E+ +Y+L ++ + P T T++
Sbjct: 1254 EERQFAIDSTS----GQVTLIGKLDYEATPAYSLVIQAVDS-------GTIPLNSTCTLN 1302
Query: 378 ISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS-IRYSIDRSSDPGR 435
I + D D P F FV+V E++ IG + ++A D D +N+ + YSI +++ G
Sbjct: 1303 IDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGT 1362
Query: 436 FFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFP 495
F + TG++ A+ LD E S + + + A + P + ++ V I V D NDN P FP
Sbjct: 1363 FS-ISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFP 1421
Query: 496 --RFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTA 553
+++ V EN G + +V+A D D NGQ Y++ + +FTI D
Sbjct: 1422 PGDIFKSIV-ENIPIGTSVISVTAHDPDADINGQ-LSYTIIQQMPRGNHFTI----DEVK 1475
Query: 554 RILTRRSGFRQQEQSVFHLPILIADSGQPVLS---STGTLTIQVCSCDDDGHVMSCSPEA 610
+ + ++ ++F L + D P+ + + +TI V +D+
Sbjct: 1476 GTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDN---------- 1525
Query: 611 YMLPVSLSRGALIA 624
+P+ +S+ AL A
Sbjct: 1526 --VPMFISQNALAA 1537
Score = 167 bits (422), Expect = 5e-41
Identities = 151/529 (28%), Positives = 247/529 (46%), Gaps = 32/529 (6%)
Query: 86 DMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRP 144
D D G + ++Y +S + F +D+ TG I L + + + A D+ P
Sbjct: 3010 DKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNP-P 3068
Query: 145 MEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVV 204
+ ++ I + + N + P+F AT+PE +G+ V V+A D D G +
Sbjct: 3069 LSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNG---LIK 3125
Query: 205 YSILQG--QPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNI 262
YSI G + F+++S TG++ T +D E + +E+ I A D GG + G +V +
Sbjct: 3126 YSISSGNEEGIFAINSSTGIL-TLAKALDYELCQKHEMTISAID-GGWVAR-TGYCSVTV 3182
Query: 263 TLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAF 322
+ DVNDN P F Y +VLE+AP +TV + A D D G NA + YT+ D +D F
Sbjct: 3183 NVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD-SDLF 3241
Query: 323 DISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVED 382
I DPN G+IT + L FE+K+SY L V+ N E R TV+I ++
Sbjct: 3242 VI--DPN--TGVITTQGFLDFETKQSYHLTVKAFNVPDEERC-------SFATVNIQLKG 3290
Query: 383 VDE-PPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVD 440
+E P F Y+ E+ E GT + + A D D+ T+ + Y I +S + F ++
Sbjct: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK-KGFQIN 3349
Query: 441 ITTGALMTARPLDREEFSWHNITVLAMEMNN--PSQVGSVPVTIKVLDVNDNAPEFPRFY 498
TG + + LDRE+ ++ VLA + + + V V + VLD ND Y
Sbjct: 3350 KKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIY 3409
Query: 499 EAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTR 558
+ E G + VSA D D + F Y + N F+I +T
Sbjct: 3410 SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIG-SGNENGAFSINPQTGQ----ITV 3464
Query: 559 RSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCS 607
+ ++ +++L +L DSG P + + +L + + +D+G +++ S
Sbjct: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVS 3513
Score = 164 bits (416), Expect = 2e-40
Identities = 134/453 (29%), Positives = 204/453 (45%), Gaps = 35/453 (7%)
Query: 73 TGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTL 132
TGTD L V SD D ++ I+ G FTI+ +TG I LDRE + YTL
Sbjct: 2379 TGTDVLLVNA--SDADASKNAVIRIIGGNSQ---FTINPSTGQIITSALLDRETKDNYTL 2433
Query: 133 RAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDA 192
D + P+ + ++ + D+NDN P+F PYV +P + G+ V VT TDA
Sbjct: 2434 VVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDA 2493
Query: 193 DDPTYGNSARVVYSIL-QGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQL 251
D G ++ + YS+ + F +D G I A EV G
Sbjct: 2494 D---IGPNSELHYSLSGRNSEKFHIDPLRGAIMAA-----GPLNGASEVTFSVHVKDG-- 2543
Query: 252 GGLAGTTTVNITLSDVNDNP-PRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMK 310
G T + +T+ VN P+ K E+ P+SS V + L M
Sbjct: 2544 GSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLR---GEPMS 2600
Query: 311 YTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPF 370
Y I G+ + F I G +++ +PL FE + Y + +E + PF
Sbjct: 2601 YYIASGNLGNTFQIDQ----LTGQVSISQPLDFEKIQKYVVWIEARDG-------GFPPF 2649
Query: 371 QDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSID 428
+ I+V DV D P+F+ + E+ E+++ I +SA D D N + Y I
Sbjct: 2650 SSYEKLDITVLDVNDNAPIFKEDPFISEILENLS-PRKILTVSAMDKDSGPNGQLDYEIV 2708
Query: 429 RSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVN 488
+ F ++ TG + + RPLDRE+ S + +T+ + + +PSQ SV V I +LD N
Sbjct: 2709 NGNMENSFS-INHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDEN 2767
Query: 489 DNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQD 521
DNAP F + + A V EN+ G + V+ D+D
Sbjct: 2768 DNAPRFSQIFSAHVPENSPLGYTVTRVTTSDED 2800
Score = 162 bits (409), Expect = 1e-39
Identities = 162/557 (29%), Positives = 259/557 (46%), Gaps = 48/557 (8%)
Query: 85 SDMDRGDGS-IKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGR 143
+D D GD + + Y ++G F+I TG I ++LD E ++ Y L A D+ GR
Sbjct: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ--GR 1397
Query: 144 PMEPES-EFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSAR 202
P + +I ++D NDN P F G ++ E P+GTSVI VTA D D G +
Sbjct: 1398 PPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADING---Q 1454
Query: 203 VVYSILQGQP---YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLA-GTT 258
+ Y+I+Q P +F++D G I T +DRE +E+ ++A D +
Sbjct: 1455 LSYTIIQQMPRGNHFTIDEVKGTIYTNA-EIDREFANLFELTVKANDQAVPIETRRYALK 1513
Query: 259 TVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDG 318
V I ++D+NDN P F ++ ++ SA I S + + A D DEG N E++Y I++GD
Sbjct: 1514 NVTILVTDLNDNVPMFISQN-ALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGD- 1571
Query: 319 ADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHI 378
D F + G + V L S+ Y L V + E R + TT + I
Sbjct: 1572 TDTFIVDR----YSGDLRVASAL-VPSQLIYNLIVSATDLGPERR-------KSTTELTI 1619
Query: 379 SVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSI----DRSSDPG 434
++ +D PVF Y + E IGT + I A P + + Y I G
Sbjct: 1620 ILQGLD-GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVG 1678
Query: 435 RFFYVDITTGALMTARPLDREEFS-WHNITVLAMEMNNP---SQVGSVPVTIKVLDVNDN 490
R F + TG + TA LDRE+ + + + V A+E + +Q V +T++ D+NDN
Sbjct: 1679 RLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQ--DINDN 1736
Query: 491 APEFPR-FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQ 549
P FP + V EN G I ++A+D D+ N Y + + + + R +
Sbjct: 1737 PPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII-----SGADDSFRIDP 1791
Query: 550 DNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPE 609
++ I TRR ++ +S + L ++ AD G + SS + I V +D S
Sbjct: 1792 ESGDLIATRR--LDRERRSKYSL-LVRADDG--LQSSDMRINITVSDVNDHTPKFSRPVY 1846
Query: 610 AYMLPVSLSRGALIAIL 626
++ +P G+L+A +
Sbjct: 1847 SFDIPEDTIPGSLVAAI 1863
Score = 154 bits (389), Expect = 3e-37
Identities = 150/542 (27%), Positives = 234/542 (43%), Gaps = 61/542 (11%)
Query: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
+F I+ +TG ++ +DRE + L P E + ++D+NDN P F
Sbjct: 80 LFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR----VLVRDLNDNAPVF 135
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY--FSVD-----S 218
D V T E S G VI TATD+D + G R Y I++G F +D S
Sbjct: 136 PDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRS-YRIIRGNEAGRFRLDITLNPS 194
Query: 219 KTGVIRTALMN--MDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQ 276
G + +DRE Y+++++ +D G G VN+T+ D+NDNPP F
Sbjct: 195 GEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKR--RGYLQVNVTVQDINDNPPVFGS 252
Query: 277 KHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIIT 336
HYQ V E A + S+V +V A D DEG NA+++Y + D + DP + G+IT
Sbjct: 253 SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD----EGTPFQMDP--ETGLIT 306
Query: 337 VKKPLSFESKKSYTLKVEGAN---PHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGF 393
V++PL FE+++ Y+L V+ + P L R L D D PV + +
Sbjct: 307 VREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVN---------DNDPVVKFRY 357
Query: 394 Y-----FVEVPEDVAIGTTIQIISAKDPD--VTNNSIRYSIDRSSDPGRFFYVDIT---- 442
+ + V E+ +GT + +++ D D N +I I + R F V +
Sbjct: 358 FPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQI-LGGNEQRHFEVQSSKVPN 416
Query: 443 TGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSV-------PVTIKVLDVNDNAPEF- 494
+ A LDRE +N+TV + +V + I V D+ND+ P F
Sbjct: 417 LSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFS 476
Query: 495 PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTAR 554
+ Y + E A G + +SA D D N Y ++ + + +++
Sbjct: 477 QQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHIS-----EHSGL 531
Query: 555 ILTRRSGFRQQE-QSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYML 613
+ T SG +E S L I D G S L + + +D+ V S PE Y +
Sbjct: 532 VTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFS-QPEGYDV 590
Query: 614 PV 615
V
Sbjct: 591 SV 592
Score = 154 bits (388), Expect = 4e-37
Identities = 161/571 (28%), Positives = 258/571 (45%), Gaps = 63/571 (11%)
Query: 73 TGTDPLYVGKLHSDMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYT 131
TGTD + V +D D G +G ++Y + F ID TG I + LDRE+ Y
Sbjct: 2169 TGTDIIQV--FAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYH 2226
Query: 132 LRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPE-MSPVGTSVIQVTAT 190
L QA DR + P S I + DIND P F PY VPE + + +++QV A
Sbjct: 2227 LTVQATDRGS-TPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVAR 2285
Query: 191 DADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKD 246
D D G+++++ Y + G S + GV ++ +DRE KE + ++I A D
Sbjct: 2286 DDDR---GSNSKLSYVLFGGNEDNAFTLSASGELGVTQS----LDRETKERFVLMITATD 2338
Query: 247 MGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGIN 306
G L GT T+N+ + DVNDN P F K Y ++ E AP + V V A D D N
Sbjct: 2339 SGSP--ALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKN 2396
Query: 307 AEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKV---EGANPHLEMR 363
A ++ I+ G+ + ST G I L E+K +YTL V + +P
Sbjct: 2397 AVIR--IIGGNSQFTINPST------GQIITSALLDRETKDNYTLVVVCSDAGSPE---- 2444
Query: 364 FLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNN 421
P +T+V ++V DV D PP F+ Y +P G+ + ++ D D+ N+
Sbjct: 2445 -----PLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNS 2499
Query: 422 SIRYSID-RSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV 480
+ YS+ R+S+ F++D GA+M A PL+ S +V + + + S V
Sbjct: 2500 ELHYSLSGRNSEK---FHIDPLRGAIMAAGPLNGA--SEVTFSVHVKDGGSFPKTDSTTV 2554
Query: 481 TIKVLDVNDNAPEFPRF---YEAFVC-ENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPE 536
T++ + N +FP+ + F+ EN L+ T++ G+ Y +
Sbjct: 2555 TVRFV----NKADFPKVRAKEQTFMFPENQPVSSLVTTITG----SSLRGEPMSYYI--- 2603
Query: 537 AANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCS 596
A+ N T + +Q +++ F + ++ V + I D G P SS L I V
Sbjct: 2604 ASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYV--VWIEARDGGFPPFSSYEKLDITVLD 2661
Query: 597 CDDDGHVMSCSPEAYMLPVSLSRGALIAILA 627
+D+ + P + +LS ++ + A
Sbjct: 2662 VNDNAPIFKEDPFISEILENLSPRKILTVSA 2692
Score = 150 bits (378), Expect = 6e-36
Identities = 142/487 (29%), Positives = 216/487 (44%), Gaps = 44/487 (9%)
Query: 116 IHAIQRLDREERAQYTLRAQALDRRTGRP------MEPESEFIIKIQDINDNEPKFLDGP 169
I LDRE Y L D P + +I + DIND+ P F
Sbjct: 420 IKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQV 479
Query: 170 YVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP--YFSVDSKTGVIRTAL 227
Y + E +P G+ V ++ATD D G +A + YSI+ G +F + +G++ T
Sbjct: 480 YRVNLSEEAPPGSYVSGISATDGDS---GLNANLRYSIVSGNGLGWFHISEHSGLVTTGS 536
Query: 228 MN-MDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKH-YQMSVLE 285
+DRE + I A+D G + + +TL DVND P F Q Y +SV+E
Sbjct: 537 SGGLDRELASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVE 594
Query: 286 SAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES 345
+AP + + + A D D G N +++++ + + D DP G ++ L E
Sbjct: 595 NAPTGTELLMLRATDGDLGDNGTVRFSLQEAE-TDRRSFRLDP--VSGRLSTISSLDREE 651
Query: 346 KKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAI 404
+ Y+L V + L P +++S+ D+ D PVF P YF + E+
Sbjct: 652 QAFYSLLVLATD-------LGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPG 704
Query: 405 GTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNIT 463
G+ I +SA DPD+ TN +++YSI + D RF V+ +G + T LDREE + + +
Sbjct: 705 GSYITTVSATDPDLGTNGTVKYSIS-AGDRSRF-QVNAQSGVISTRMALDREEKTAYQLQ 762
Query: 464 VLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCENAKAGQLIQTVSAVDQDD 522
++A + N VTI VLD DN P F + Y V EN G + +VSA D
Sbjct: 763 IVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL 822
Query: 523 PRNGQHFYYSLAPEAANNPNFTIRD--NQDNTARILTRRSGFRQQEQSVFHLPILIADSG 580
N + L F I Q TA ++ R +EQS + L ++ SG
Sbjct: 823 NSNISY----LITTGDQKGMFAINQVTGQLTTANVIDR------EEQSFYQLKVVA--SG 870
Query: 581 QPVLSST 587
V T
Sbjct: 871 GTVTGDT 877
Score = 145 bits (367), Expect = 1e-34
Identities = 157/545 (28%), Positives = 239/545 (43%), Gaps = 52/545 (9%)
Query: 85 SDMDRG-DGSIKY-ILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTG 142
+D D G +G I+Y I++G+ F +D +GD+ L + Y L A D
Sbjct: 1553 ADPDEGANGEIEYEIINGDTD--TFIVDRYSGDLRVASALVPSQLI-YNLIVSATDLGPE 1609
Query: 143 RPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSAR 202
R + +E I +Q ++ P F Y+ + E P+GT+VI + A G+ A
Sbjct: 1610 R-RKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIGTNVISIEAASPR----GSEAP 1662
Query: 203 VVYSILQGQ-------PYFSVDSKTGVIRTALMNMDREAKE-YYEVIIQAKDMGGQLGGL 254
V Y I+ + F++ TG+I+TA + +DRE Y V + A +
Sbjct: 1663 VEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAI-LDREQGACLYLVDVYAIEKSTAFPRT 1721
Query: 255 AGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIV 314
V ITL D+NDNPP FP ++V E+ S + ++ A D DEG NA + YTI+
Sbjct: 1722 Q-RAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII 1780
Query: 315 DGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTT 374
G D+F I DP + G + + L E + Y+L V + G
Sbjct: 1781 SG-ADDSFRI--DP--ESGDLIATRRLDRERRSKYSLLVRADD----------GLQSSDM 1825
Query: 375 TVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSD 432
++I+V DV D P F Y ++PED G+ + I A D D N I Y ++ +
Sbjct: 1826 RINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDE 1885
Query: 433 PGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAP 492
G FF I TG R LD E ++ +TV A + Q ++ V +LDVNDN P
Sbjct: 1886 DGIFFLNPI-TGVFNLTRLLDYEVQQYYILTVRAED--GGGQFTTIRVYFNILDVNDNPP 1942
Query: 493 EFP-RFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDN 551
F Y + EN G + + D DD N Q YS+A + FT+ N
Sbjct: 1943 IFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQ-LTYSIA-SGDSLGQFTVDKN--- 1997
Query: 552 TARILTRRSGFRQQEQSVFHLPILIADSGQ-PVLSSTGTLTIQVCSCD-DDGHVMSCSPE 609
+L ++ QS ++L + + D Q P T T + + D +D SP+
Sbjct: 1998 --GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPK 2055
Query: 610 AYMLP 614
+P
Sbjct: 2056 LTYIP 2060
Score = 115 bits (288), Expect = 2e-25
Identities = 125/470 (26%), Positives = 206/470 (43%), Gaps = 40/470 (8%)
Query: 74 GTDPLYVGKLHSDMDRGDGSIKY-ILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTL 132
GT + V D D +G + Y I+ G FTID+ G I+ +DRE + L
Sbjct: 1436 GTSVISVTAHDPDADI-NGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFEL 1494
Query: 133 RAQALDRRTGRPMEPE----SEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVT 188
+A D+ P+E I + D+NDN P F+ +A P + +G+ + +
Sbjct: 1495 TVKANDQAV--PIETRRYALKNVTILVTDLNDNVPMFISQNALAADPS-AVIGSVLTTIM 1551
Query: 189 ATDADDPTYGNSARVVYSILQGQ-PYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDM 247
A D D+ G + + Y I+ G F VD +G +R A + + Y +I+ A D+
Sbjct: 1552 AADPDE---GANGEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQL--IYNLIVSATDL 1606
Query: 248 GGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINA 307
G + TT + I L ++ P F Q Y + E PI + V + A G A
Sbjct: 1607 GPE--RRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEA 1661
Query: 308 EMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL----EMR 363
++Y IV + + + T+ + + + +GA +L +
Sbjct: 1662 PVEYYIV--------SVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIE 1713
Query: 364 FLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNS 422
P V I+++D+ D PPVF + V E++ G+ I ++A D D N+
Sbjct: 1714 KSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANA 1773
Query: 423 -IRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVT 481
+ Y+I +D F +D +G L+ R LDRE S +++ V A ++ Q + +
Sbjct: 1774 LVTYTIISGADDS--FRIDPESGDLIATRRLDRERRSKYSLLVRA---DDGLQSSDMRIN 1828
Query: 482 IKVLDVNDNAPEFPR-FYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFY 530
I V DVND+ P+F R Y + E+ G L+ + A D D NG+ Y
Sbjct: 1829 ITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITY 1878
Score = 70.9 bits (172), Expect = 5e-12
Identities = 64/202 (31%), Positives = 89/202 (44%), Gaps = 14/202 (6%)
Query: 74 GTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLR 133
GT +V SD Y + F+I+ TG I LDRE Y L
Sbjct: 3420 GTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
Query: 134 AQALDRRTGRPMEPES-EFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDA 192
A+D +G P S ++ ++DINDN P V E GT V+ + +TD
Sbjct: 3480 VLAVD--SGTPSATGSASLLVTLEDINDNGPMLTVSE--GEVMENKRPGTLVMTLQSTDP 3535
Query: 193 DDPTYGNSARVVYSILQGQP---YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGG 249
D P N Y +L P YFS+ S GV+ T +DRE + + + KD G
Sbjct: 3536 DLPP--NQGPFTYYLLSTGPATSYFSL-STAGVLSTT-REIDREQIADFYLSVVTKDSG- 3590
Query: 250 QLGGLAGTTTVNITLSDVNDNP 271
+ ++ T TV+IT+ D NDNP
Sbjct: 3591 -VPQMSSTGTVHITVIDQNDNP 3611
Score = 47.8 bits (112), Expect = 4e-05
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 12/186 (6%)
Query: 429 RSSDPGRFFYVDITTGALMTARPLDREEFSWH--NITVLAMEMNNPSQVGSVPVTIKVLD 486
R S+ F ++ +TGAL T +DRE N+ VL+ P++ V + V D
Sbjct: 73 RLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTE-----VRVLVRD 127
Query: 487 VNDNAPEFP-RFYEAFVCENAKAGQLIQTVSAVDQDDPRNG-QHFYYSL--APEAAN-NP 541
+NDNAP FP E++ +G+ + +A D D NG H Y + EA
Sbjct: 128 LNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRL 187
Query: 542 NFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDG 601
+ T+ + + L + G ++ + L + + D G+P + + V +D+
Sbjct: 188 DITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNP 247
Query: 602 HVMSCS 607
V S
Sbjct: 248 PVFGSS 253
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 219 bits (559), Expect = 6e-57
Identities = 223/821 (27%), Positives = 362/821 (44%), Gaps = 109/821 (13%)
Query: 52 QSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGA------GI 105
Q +R+KR WV + EE G P +G+L ++M + S+ Y++SG G G+
Sbjct: 47 QPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGL 105
Query: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
D G I+ + +DRE +T+ ++R TG+ ++ F I+I D+ND+ P+F
Sbjct: 106 FSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQF 165
Query: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY-----FSVDSKT 220
+ + TV E G + Q+ A D D+ NS +V+Y ++ P F VD +
Sbjct: 166 PEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLS 224
Query: 221 GVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQ 280
G IR + +D E + ++I+A+D G L+ TTTV++ + + N++ P F Q++Y+
Sbjct: 225 GEIRLSGC-LDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYK 281
Query: 281 MSVLESAPISSTVGRVFAKDLDEGINA--EMKYTIVDGDGADAFDISTDPNFQVGIITVK 338
+ + E S V R+ +D D + K+ I+ G+ FDISTDP GI+ V
Sbjct: 282 VQIPEGR-ASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVI 340
Query: 339 KPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQD------TTTVHISVEDVDEPPVFEPG 392
KPL +E++ + +L + N + F G Q + TV + V D ++PP F P
Sbjct: 341 KPLDYETRPAQSLIIVVENEE-RLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQ 399
Query: 393 FYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPL 452
+ V E GT + +A DPD + IRY + DP + VD +G ++T P+
Sbjct: 400 SFIVNKEEGARPGTLLGTFNAMDPD---SQIRYEL--VHDPANWVSVDKNSGVVITVEPI 454
Query: 453 DRE----EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAK 507
DRE S++ I + A++ P Q + + + + D+NDN P PR VCE+A
Sbjct: 455 DRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAV 514
Query: 508 AGQLIQTVSAVDQDDPRNGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQE 566
L + A D D F + L N + + N + +LT RS
Sbjct: 515 HEPL--HIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRS----LP 568
Query: 567 QSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAIL 626
+ + +P+ I D + LS T+ +++C C ++C E V L GAL +
Sbjct: 569 RGNYLVPLFIGD--KQGLSQKQTVHVRICPCASG---LTC-VELADAEVGLHVGALFPVC 622
Query: 627 ACIFVLLVLVLLILS---MRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAM 683
A L V +L +L + ++ + ++E H+ +V Y+ E G A
Sbjct: 623 AAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEG-HQTLVMYNAESKGTS-------AQT 674
Query: 684 WNPREAQ--------AGAAPKTRQDMLPEI--ESLSRYVPQTCAVNS------------- 720
W+ E Q A A P L E+ + S+ CA+ S
Sbjct: 675 WSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVK 734
Query: 721 -----------TVHSYVLA------------KLYEADMDLWAPPFDSLQTYMFEGDGSVA 757
T+H +LA KL+ A++ L P Y EG+ A
Sbjct: 735 NIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANV-LEDDPGYLPHVYSEEGECGGA 793
Query: 758 GSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASEGPA 798
SLSSL A+ + E D L G + E+Y S P+
Sbjct: 794 PSLSSL--ASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,025,266
Number of Sequences: 37866
Number of extensions: 1421482
Number of successful extensions: 9167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3304
Number of HSP's gapped (non-prelim): 771
length of query: 801
length of database: 18,247,518
effective HSP length: 110
effective length of query: 691
effective length of database: 14,082,258
effective search space: 9730840278
effective search space used: 9730840278
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.