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Search of human proteins with 157738694
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157738694 G protein-coupled receptor 109B [Homo sapiens] 805 0.0
gi|29171311 G protein-coupled receptor 109A [Homo sapiens] 714 0.0
gi|14211851 G protein-coupled receptor 81 [Homo sapiens] 345 3e-95
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] 224 1e-58
gi|153792268 G protein-coupled receptor 31 [Homo sapiens] 191 1e-48
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 157 2e-38
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 143 3e-34
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 143 3e-34
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 143 3e-34
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 143 3e-34
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 142 4e-34
gi|33695097 G protein-coupled receptor 35 [Homo sapiens] 140 2e-33
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 136 3e-32
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 132 5e-31
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 132 5e-31
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 132 5e-31
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 130 2e-30
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 129 3e-30
gi|166362740 coagulation factor II receptor precursor [Homo sapi... 127 2e-29
gi|4557359 bradykinin receptor B2 [Homo sapiens] 127 2e-29
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 126 4e-29
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 126 4e-29
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 126 4e-29
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 126 4e-29
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 126 4e-29
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 125 5e-29
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 125 6e-29
gi|4506241 platelet-activating factor receptor [Homo sapiens] 125 8e-29
gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 123 3e-28
gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 123 3e-28
>gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
Length = 387
Score = 805 bits (2078), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60
MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
Sbjct: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60
Query: 61 SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV 120
SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV
Sbjct: 61 SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV 120
Query: 121 VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF 180
VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF
Sbjct: 121 VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF 180
Query: 181 SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240
SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
Sbjct: 181 SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240
Query: 241 VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300
VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
Sbjct: 241 VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300
Query: 301 FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP 360
FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP
Sbjct: 301 FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP 360
Query: 361 TSNNHSKKGHCHQEPASLEKQLGCCIE 387
TSNNHSKKGHCHQEPASLEKQLGCCIE
Sbjct: 361 TSNNHSKKGHCHQEPASLEKQLGCCIE 387
>gi|29171311 G protein-coupled receptor 109A [Homo sapiens]
Length = 363
Score = 714 bits (1842), Expect = 0.0
Identities = 345/362 (95%), Positives = 353/362 (97%)
Query: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60
MNRHHLQDHFLEIDKKNCCVFRDDFI KVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
Sbjct: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60
Query: 61 SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV 120
SSRIFLFNLAVADFLLIICLPF+MD YVRR DWKFGDIPCRL+LFM AMNRQGSIIFLTV
Sbjct: 61 SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV 120
Query: 121 VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF 180
VAVDRYFRVVHPHHALNKISN TAAIISCLLWGIT+GLTVHLLKKK+ IQNG AN+C SF
Sbjct: 121 VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF 180
Query: 181 SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240
SICHTF+WHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
Sbjct: 181 SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240
Query: 241 VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300
VICFLPSVVVRI IFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
Sbjct: 241 VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300
Query: 301 FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP 360
FPNFFSTLINRCLQRK+TGEPDNNRSTSVELTGDPNKTRGAPEAL+ANSGEPWSPSYLGP
Sbjct: 301 FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP 360
Query: 361 TS 362
TS
Sbjct: 361 TS 362
>gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
Length = 346
Score = 345 bits (886), Expect = 3e-95
Identities = 177/317 (55%), Positives = 223/317 (70%), Gaps = 6/317 (1%)
Query: 17 NCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76
+CC D I++V+PP+L + F+ G LGNG+AL FCFH+K+WK S ++LFNLAVADFLL
Sbjct: 5 SCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLL 64
Query: 77 IICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHAL 136
+ICLPF DYY+RR W FGDIPCR+ LF AMNR GSI+FLTVVA DRYF+VVHPHHA+
Sbjct: 65 MICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAV 124
Query: 137 NKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLE 196
N IS AA I C LW + + TV+LL + L TA C SF + WH+ MF LE
Sbjct: 125 NTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLE 184
Query: 197 FFLPLGIILFCSARIIWSLRQR-QMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIF 255
FF+PLGIILFCS +I+WSLR+R Q+ R A++K+A FIMVVAIVF+ C+LPSV R++
Sbjct: 185 FFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFL 244
Query: 256 WLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR 315
W + +S C+ SV A ITLSFTYMNSMLDP+VYYFSSPSFP F++ L L+
Sbjct: 245 WTVPSSA---CD--PSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKP 299
Query: 316 KITGEPDNNRSTSVELT 332
K G R + ++
Sbjct: 300 KQPGHSKTQRPEEMPIS 316
>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
Length = 423
Score = 224 bits (570), Expect = 1e-58
Identities = 122/294 (41%), Positives = 177/294 (60%), Gaps = 24/294 (8%)
Query: 18 CCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLI 77
C ++ L P+L LEF+ GL+GN LAL+IFC H + W S+ +FL +L ADFLLI
Sbjct: 83 CHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLI 142
Query: 78 ICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALN 137
LP +DYY+ W+FG C++ LFM + NR S++FLT +A++RY +VV PHH L+
Sbjct: 143 SNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLS 202
Query: 138 KISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSI----CHTFRWHEAMF 193
+ S AA ++ LW VG+ LL LL+ + C+S+ + + RWH+A++
Sbjct: 203 RASVGAAARVAGGLW---VGIL--LLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALY 257
Query: 194 LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVV---V 250
LLEFFLPL +ILF I ++R R + A +RA+ + +V V+ ICFLPS++
Sbjct: 258 LLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMA 317
Query: 251 RIHIFWLLHTSGTQNCEVYRSVDLA---FFITLSFTYMNSMLDPVVYYFSSPSF 301
+ FWL RS+DL F +L+FTY+NS+LDPV+Y FSSP+F
Sbjct: 318 SMVAFWL---------SACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNF 362
>gi|153792268 G protein-coupled receptor 31 [Homo sapiens]
Length = 319
Score = 191 bits (485), Expect = 1e-48
Identities = 113/317 (35%), Positives = 169/317 (53%), Gaps = 27/317 (8%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C +A + +LGLE GLLGN +ALW F F ++ WK ++L NLA+AD LL
Sbjct: 6 CSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAA 65
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
CLPF+ +Y+ W G + C + F+ ++R + FL VA+DRY RVVHP +N
Sbjct: 66 CLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNL 125
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFR----------W 188
+S A +S L+W + V LT L QN T CH+F W
Sbjct: 126 LSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTR--------CHSFYSRADGSFSIIW 177
Query: 189 HEAMFLLEFFLPLGIILFCSARIIWSL--RQRQMDRHAKIKRAITFIMVVAIVFVICFLP 246
EA+ L+F LP G+I+FC+A II +L R R+ ++ K++RA + +V ++F +CFLP
Sbjct: 178 QEALSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLP 237
Query: 247 SVVVRI--HIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304
+ R+ HIF +C +V +T S TY++S+L+PVVY FSSP+F +
Sbjct: 238 CFLARVLMHIF-----QNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSS 292
Query: 305 FSTLINRCLQRKITGEP 321
+ + + + EP
Sbjct: 293 YRRVFHTLRGKGQAAEP 309
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 157 bits (396), Expect = 2e-38
Identities = 93/312 (29%), Positives = 160/312 (51%), Gaps = 22/312 (7%)
Query: 18 CCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLI 77
C + + F LP V L FI G LGN +A+W+F FH+K W +++FNLA+ADFL +
Sbjct: 42 CALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYV 101
Query: 78 ICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALN 137
+ LP ++ YY ++DW FGD C+L F+F +N GSI+FLT ++ RY VV+P +L
Sbjct: 102 LTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLG 161
Query: 138 KISNWTAAIISCLLWGITVGLTVHLL---------KKKLLIQNGTANVCIS----FSICH 184
++ A IS L+W I V +L K + + T++ + +S+C
Sbjct: 162 RLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCT 221
Query: 185 TFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICF 244
T + F +PL +IL C I+ +L + +D +++I +++V VF + +
Sbjct: 222 T--------VAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSY 273
Query: 245 LPSVVVR-IHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303
+P V++ +++ L C V + +T +NS +DP++Y+ + +F
Sbjct: 274 IPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRR 333
Query: 304 FFSTLINRCLQR 315
S + +R
Sbjct: 334 RLSRATRKASRR 345
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 143 bits (360), Expect = 3e-34
Identities = 95/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)
Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKF 95
L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + Y+ + W F
Sbjct: 40 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 99
Query: 96 GDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGIT 155
G+I CRL F+F +N SI FLT ++ DR+ +VHP +L A + LW +
Sbjct: 100 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 159
Query: 156 VGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLL--EFFLPLGIILFCSARIIW 213
LL +Q VC+ + H A+ L F P + C II
Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVCL--QLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 217
Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIFWLLHTSGTQNCEVYRSV 272
SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R +
Sbjct: 218 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 275
Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGEP 321
LA IT T +N LDP++Y+F + F + L N +++ G P
Sbjct: 276 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 321
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 143 bits (360), Expect = 3e-34
Identities = 95/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)
Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKF 95
L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + Y+ + W F
Sbjct: 40 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 99
Query: 96 GDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGIT 155
G+I CRL F+F +N SI FLT ++ DR+ +VHP +L A + LW +
Sbjct: 100 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 159
Query: 156 VGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLL--EFFLPLGIILFCSARIIW 213
LL +Q VC+ + H A+ L F P + C II
Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVCL--QLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 217
Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIFWLLHTSGTQNCEVYRSV 272
SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R +
Sbjct: 218 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 275
Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGEP 321
LA IT T +N LDP++Y+F + F + L N +++ G P
Sbjct: 276 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 321
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 143 bits (360), Expect = 3e-34
Identities = 95/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)
Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKF 95
L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + Y+ + W F
Sbjct: 68 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 127
Query: 96 GDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGIT 155
G+I CRL F+F +N SI FLT ++ DR+ +VHP +L A + LW +
Sbjct: 128 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 187
Query: 156 VGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLL--EFFLPLGIILFCSARIIW 213
LL +Q VC+ + H A+ L F P + C II
Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVCL--QLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 245
Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIFWLLHTSGTQNCEVYRSV 272
SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R +
Sbjct: 246 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 303
Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGEP 321
LA IT T +N LDP++Y+F + F + L N +++ G P
Sbjct: 304 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 349
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 143 bits (360), Expect = 3e-34
Identities = 95/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)
Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKF 95
L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + Y+ + W F
Sbjct: 68 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 127
Query: 96 GDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGIT 155
G+I CRL F+F +N SI FLT ++ DR+ +VHP +L A + LW +
Sbjct: 128 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 187
Query: 156 VGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLL--EFFLPLGIILFCSARIIW 213
LL +Q VC+ + H A+ L F P + C II
Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVCL--QLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 245
Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIFWLLHTSGTQNCEVYRSV 272
SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R +
Sbjct: 246 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 303
Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGEP 321
LA IT T +N LDP++Y+F + F + L N +++ G P
Sbjct: 304 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 349
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 142 bits (359), Expect = 4e-34
Identities = 88/309 (28%), Positives = 157/309 (50%), Gaps = 16/309 (5%)
Query: 10 FLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNL 69
F + +NC + ++F + P V + F +G+LGNGL++++F K S +F+ NL
Sbjct: 23 FSNNNSRNCTI--ENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNL 80
Query: 70 AVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRV 129
A++D L I LPF DYY+R S+W FGD+ CR++ + +N SI FLTV++V R+ +
Sbjct: 81 AISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAM 140
Query: 130 VHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWH 189
VHP L+ S +A I+ ++W + + ++ LL QNG+ C+ ++ +
Sbjct: 141 VHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSG-SEQNGSVTSCLELNLYKIAKLQ 199
Query: 190 EAMF-------LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVI 242
+ LL FF L I R++ + + ++A+T I++ I+F +
Sbjct: 200 TMNYIALVVGCLLPFF-TLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFL 258
Query: 243 CFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFP 302
CFLP H +H + + + A ITL+ N+ +P++YYF+ +F
Sbjct: 259 CFLP-----YHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFK 313
Query: 303 NFFSTLINR 311
+ + + +
Sbjct: 314 DRLKSALRK 322
>gi|33695097 G protein-coupled receptor 35 [Homo sapiens]
Length = 309
Score = 140 bits (353), Expect = 2e-33
Identities = 93/274 (33%), Positives = 139/274 (50%), Gaps = 23/274 (8%)
Query: 34 LGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDW 93
LG+ + GLL N LALW+FC ++ W +RI++ NLAVAD L+ LPFV+ SD
Sbjct: 27 LGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDT 86
Query: 94 KFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWG 153
C+L ++ NR SI +T +AVDRY V HP A S AA + +LW
Sbjct: 87 PL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWV 142
Query: 154 ITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIW 213
+ +G V + L IQ G C S H F A LL F+LPL +++FCS +++
Sbjct: 143 LVIGSLV--ARWLLGIQEG--GFCFR-STRHNFN-SMAFPLLGFYLPLAVVVFCSLKVVT 196
Query: 214 SLRQR---QMDRHAKIKRAITFIMVVAIVFVICFLP---SVVVRIHIFWLLHTSGTQNCE 267
+L QR + + ++A + +VFV+CFLP + VR+ + W C
Sbjct: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW-------NACA 249
Query: 268 VYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
+ ++ A +IT + N LD + YY+ + F
Sbjct: 250 LLETIRRALYITSKLSDANCCLDAICYYYMAKEF 283
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 136 bits (343), Expect = 3e-32
Identities = 89/297 (29%), Positives = 150/297 (50%), Gaps = 11/297 (3%)
Query: 17 NCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76
N C+ D F + V + FI GL+ N ++L++FCF +K + IF+ NLAV+D L
Sbjct: 29 NTCIVDDSFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLF 88
Query: 77 IICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHAL 136
+ LPF + Y R W FGD C++ F N GS++FLT ++VDR+ +V+P +
Sbjct: 89 VCTLPFKIFYNFNR-HWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSR 147
Query: 137 NKISNWTAAIISCLLWGITV--GLTVHLLKKKLLIQNGTANVCISFS--ICHTFRWHEAM 192
+ +AI+ +W + + G++ L + N T FS + T+ +
Sbjct: 148 TIRTRRNSAIVCAGVWILVLSGGISASLF-STTNVNNATTTCFEGFSKRVWKTYLSKITI 206
Query: 193 FL--LEFFLPLGIILFCSARIIWSLRQ--RQMDRHAKIKRAITFIMVVAIVFVICFLPSV 248
F+ + F +PL + + CS+ ++ +LR+ K+ + I V VFV+CF+P
Sbjct: 207 FIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYN 266
Query: 249 VVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFF 305
V + ++ L+ + NC + R + + ITL +N DP +YYF+ SF F
Sbjct: 267 SV-LFLYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSF 322
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 132 bits (332), Expect = 5e-31
Identities = 81/294 (27%), Positives = 147/294 (50%), Gaps = 11/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L +
Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LPF + Y+ R+ W FGD+ C++ + +F N GSI+FLT ++VDR+ +V+P +
Sbjct: 69 TLPFRIFYFTTRN-WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127
Query: 139 ISNWTAAIISCLLWGITVG--LTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMF--- 193
+ A I+ +W +G ++ N + C T++ + +
Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187
Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249
++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P
Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246
Query: 250 VRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303
+ + ++ L+ T NC V +V + ITL N DP+VYYF+S + N
Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 132 bits (332), Expect = 5e-31
Identities = 81/294 (27%), Positives = 147/294 (50%), Gaps = 11/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L +
Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LPF + Y+ R+ W FGD+ C++ + +F N GSI+FLT ++VDR+ +V+P +
Sbjct: 69 TLPFRIFYFTTRN-WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127
Query: 139 ISNWTAAIISCLLWGITVG--LTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMF--- 193
+ A I+ +W +G ++ N + C T++ + +
Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187
Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249
++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P
Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246
Query: 250 VRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303
+ + ++ L+ T NC V +V + ITL N DP+VYYF+S + N
Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 132 bits (332), Expect = 5e-31
Identities = 81/294 (27%), Positives = 147/294 (50%), Gaps = 11/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L +
Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LPF + Y+ R+ W FGD+ C++ + +F N GSI+FLT ++VDR+ +V+P +
Sbjct: 69 TLPFRIFYFTTRN-WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127
Query: 139 ISNWTAAIISCLLWGITVG--LTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMF--- 193
+ A I+ +W +G ++ N + C T++ + +
Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187
Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249
++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P
Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246
Query: 250 VRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303
+ + ++ L+ T NC V +V + ITL N DP+VYYF+S + N
Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 130 bits (328), Expect = 2e-30
Identities = 90/298 (30%), Positives = 149/298 (50%), Gaps = 16/298 (5%)
Query: 13 IDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVA 72
+D+ + V LP V + F+ GL NG+ALW+F F K + I++ NLA+A
Sbjct: 61 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA 120
Query: 73 DFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHP 132
D L +I P + Y++ ++W +G+ C +++ F N SI+F+T ++V RY+ +V+P
Sbjct: 121 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP 180
Query: 133 HHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAM 192
K +N A IS +W + + +T+ L K I N+ + M
Sbjct: 181 MGHSRKKAN-IAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDM 239
Query: 193 FLLEFFLPLGIILF-----CSARI--IWSLRQRQMDRHA--KIKRAITFIMVVAIVFVIC 243
F L +G+ LF SA + I LR MD ++ K KRAI I+ V +++IC
Sbjct: 240 FNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLIC 299
Query: 244 FLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
F PS ++ + ++L+ + G + V + + L + +NS +DP VYYF S F
Sbjct: 300 FTPSNLLLVVHYFLIKSQGQSH------VYALYIVALCLSTLNSCIDPFVYYFVSHDF 351
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 129 bits (325), Expect = 3e-30
Identities = 84/290 (28%), Positives = 139/290 (47%), Gaps = 10/290 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C F +DF +LP + F+ GL N LW+F F L+ W ++ ++F+LA++D L ++
Sbjct: 27 CWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVL 86
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ YY + W FG C+ V F+F N S++FLT ++V RY + HP AL
Sbjct: 87 SLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRW 146
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFS----ICHTFRWHEAMFL 194
A ++ +W + G V L GT +C + H + A+
Sbjct: 147 GRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMG 206
Query: 195 LEFFLPLGIILFC---SARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVR 251
L F +P + L C AR ++ +++ R++ I VV VF +CF+P + R
Sbjct: 207 LLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRL-RSLRTIAVVLTVFAVCFVPFHITR 265
Query: 252 IHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
I++L +C V V++ + +T NS LDPV+Y + +
Sbjct: 266 T-IYYLARLL-EADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKY 313
>gi|166362740 coagulation factor II receptor precursor [Homo
sapiens]
Length = 425
Score = 127 bits (319), Expect = 2e-29
Identities = 81/288 (28%), Positives = 141/288 (48%), Gaps = 14/288 (4%)
Query: 30 LPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVR 89
+P V F+ L N +A+ +F +K K + +++ +LA AD L + LPF + YY
Sbjct: 105 VPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFS 164
Query: 90 RSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISC 149
SDW+FG CR V F N SI+ +TV+++DR+ VV+P +L+ + A+
Sbjct: 165 GSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCL 224
Query: 150 LLWGITVGLTVHLLKKKLLIQNGTANVCISFSIC-------HTFRWHEAMFLLEFFLPLG 202
+W + + V LL K+ IQ N+ + + + A + FF+PL
Sbjct: 225 AIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLI 284
Query: 203 IILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRI-HIFWLLHTS 261
I C II L + +K RA+ V +F+ICF P+ V+ I H +L HTS
Sbjct: 285 ISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTS 344
Query: 262 GTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLI 309
T+ + A+ + + + ++ +DP++YY++S + +++
Sbjct: 345 TTE------AAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSIL 386
>gi|4557359 bradykinin receptor B2 [Homo sapiens]
Length = 391
Score = 127 bits (318), Expect = 2e-29
Identities = 90/284 (31%), Positives = 140/284 (49%), Gaps = 14/284 (4%)
Query: 29 VLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYV 88
+ PP L + F+ L N L +FC H S + I+L NLA AD +L LPF
Sbjct: 59 IQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITIS 118
Query: 89 RRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIIS 148
DW FG+ CR+V + +MN SI FL +V++DRY +V A + S
Sbjct: 119 NNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYS 178
Query: 149 CLLWGITVGLTVHLLKKKLLIQ------NGTANVCISFSICHTFRWHEAMFLLEFFLPLG 202
++WG T+ L+ +L + + + N TA V S+ + + ++ F LPL
Sbjct: 179 LVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLS 238
Query: 203 IILFCSARIIWSLRQRQMDRHAKI---KRAITFIMVVAIVFVICFLPSVVVRIHIFW-LL 258
+I FC+ +I+ LR +M + +I +RA ++VV ++F+IC+LP +I F L
Sbjct: 239 VITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLP---FQISTFLDTL 295
Query: 259 HTSG-TQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
H G +C+ R +D+ I Y NS L+P+VY F
Sbjct: 296 HRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRF 339
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 126 bits (316), Expect = 4e-29
Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L
Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ YY R W F + C+LV F+F N SI+FLT ++V R V+ P +L
Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTF----RWHEAMFL 194
A ++ +W + + +L G C S F + M
Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204
Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250
L F +P +IL C + L + + RA + I VV VF +CFLP V
Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264
Query: 251 RIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304
R + S +C ++++A+ +T NS LDPV+Y+ + F
Sbjct: 265 R--TLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 126 bits (316), Expect = 4e-29
Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L
Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ YY R W F + C+LV F+F N SI+FLT ++V R V+ P +L
Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTF----RWHEAMFL 194
A ++ +W + + +L G C S F + M
Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204
Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250
L F +P +IL C + L + + RA + I VV VF +CFLP V
Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264
Query: 251 RIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304
R + S +C ++++A+ +T NS LDPV+Y+ + F
Sbjct: 265 R--TLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 126 bits (316), Expect = 4e-29
Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L
Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ YY R W F + C+LV F+F N SI+FLT ++V R V+ P +L
Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTF----RWHEAMFL 194
A ++ +W + + +L G C S F + M
Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204
Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250
L F +P +IL C + L + + RA + I VV VF +CFLP V
Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264
Query: 251 RIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304
R + S +C ++++A+ +T NS LDPV+Y+ + F
Sbjct: 265 R--TLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 126 bits (316), Expect = 4e-29
Identities = 96/322 (29%), Positives = 157/322 (48%), Gaps = 22/322 (6%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C + ++ VL + FI GL+GN +AL++F + S +I+L N+A+AD LLI
Sbjct: 46 CPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIF 105
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
CLPF + Y++ ++ W G I C++V +F MN SII L +++DRY ++
Sbjct: 106 CLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKA 165
Query: 139 ISNWTAAIISCLLWGITVG--LTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMF--- 193
I+ + + C++W + +G LT+ +L K N T +C + H + EA+F
Sbjct: 166 ITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNST--MCFHYRDKHNAK-GEAIFNFI 222
Query: 194 -LLEFFLPLGIILFCSARIIWSL-----RQRQMDRHAKIKRAITFIMVVAIVFVICFLPS 247
++ F+L +I+ +I +L R+ + K +V I+F ICF+P
Sbjct: 223 LVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPY 282
Query: 248 VVVR-IHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFS 306
R I+I L+ S E+ + + SF NS LDPV+Y+ S +
Sbjct: 283 HAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSF---NSCLDPVMYFLMSSNIRKIMC 339
Query: 307 TLINRCLQRKITGEPDNNRSTS 328
L L R+ GEP + STS
Sbjct: 340 QL----LFRRFQGEPSRSESTS 357
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 126 bits (316), Expect = 4e-29
Identities = 96/322 (29%), Positives = 157/322 (48%), Gaps = 22/322 (6%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
C + ++ VL + FI GL+GN +AL++F + S +I+L N+A+AD LLI
Sbjct: 46 CPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIF 105
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
CLPF + Y++ ++ W G I C++V +F MN SII L +++DRY ++
Sbjct: 106 CLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKA 165
Query: 139 ISNWTAAIISCLLWGITVG--LTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMF--- 193
I+ + + C++W + +G LT+ +L K N T +C + H + EA+F
Sbjct: 166 ITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNST--MCFHYRDKHNAK-GEAIFNFI 222
Query: 194 -LLEFFLPLGIILFCSARIIWSL-----RQRQMDRHAKIKRAITFIMVVAIVFVICFLPS 247
++ F+L +I+ +I +L R+ + K +V I+F ICF+P
Sbjct: 223 LVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPY 282
Query: 248 VVVR-IHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFS 306
R I+I L+ S E+ + + SF NS LDPV+Y+ S +
Sbjct: 283 HAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSF---NSCLDPVMYFLMSSNIRKIMC 339
Query: 307 TLINRCLQRKITGEPDNNRSTS 328
L L R+ GEP + STS
Sbjct: 340 QL----LFRRFQGEPSRSESTS 357
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 125 bits (315), Expect = 5e-29
Identities = 86/305 (28%), Positives = 139/305 (45%), Gaps = 11/305 (3%)
Query: 11 LEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFC--FHLKSWKSSRIFLFN 68
L + C DDF +V + + + G GNG L++ +H KS + ++++ N
Sbjct: 7 LTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKS--AFQVYMIN 64
Query: 69 LAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFR 128
LAVAD L + LP + YYV + W FGD CRL + +N SI F+T ++ R
Sbjct: 65 LAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIA 124
Query: 129 VVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCI-----SFSIC 183
+V P +N ++ A + +W + + L K C + +
Sbjct: 125 IVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKN 184
Query: 184 HTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRH-AKIKRAITFIMVVAIVFVI 242
H H + F +P II+ C II +L ++ M ++ + K+AI IMVV F++
Sbjct: 185 HVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLV 244
Query: 243 CFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFP 302
F+P + R LH T+ C+ + + ITLS N DP++Y+FS +F
Sbjct: 245 SFMPYHIQRTIHLHFLHNE-TKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFR 303
Query: 303 NFFST 307
ST
Sbjct: 304 KRLST 308
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 125 bits (314), Expect = 6e-29
Identities = 87/294 (29%), Positives = 148/294 (50%), Gaps = 24/294 (8%)
Query: 26 IAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMD 85
I ++ V + F+ GL+GN L +++ + K ++ I++FNLA+AD L+ +PF
Sbjct: 58 IPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQST 117
Query: 86 YYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAA 145
Y+ S W FGD+ C++V+ + N SI LT+++VDRY V HP AL+ + A
Sbjct: 118 VYLMNS-WPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK 176
Query: 146 IISCLLW--GITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHE-----AMFLLEFF 198
II+ +W +VG++ +L + ++ C + W + +F+ F
Sbjct: 177 IINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFV 236
Query: 199 LPLGIILFCSARIIWSLR-------QRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVR 251
+P+ II+ C +I L+ R+ DR+ ++R ++VV VFV+C+ P
Sbjct: 237 IPVLIIIVCYTLMILRLKSVRLLSGSREKDRN--LRRITRLVLVVVAVFVVCWTP----- 289
Query: 252 IHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFF 305
IHIF L+ G+ + F I L +T NS L+P++Y F +F F
Sbjct: 290 IHIFILVEALGSTSHSTAALSSYYFCIALGYT--NSSLNPILYAFLDENFKRCF 341
>gi|4506241 platelet-activating factor receptor [Homo sapiens]
Length = 342
Score = 125 bits (313), Expect = 8e-29
Identities = 92/319 (28%), Positives = 148/319 (46%), Gaps = 32/319 (10%)
Query: 24 DFIAKVLPPVLGLEFIFGLLGNGLALWIFC--FHLKSWKSSRIFLFNLAVADFLLIICLP 81
+F + P V + F+ G++ NG LW+F + K + +IF+ NL +AD L +I LP
Sbjct: 12 EFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLP 71
Query: 82 FVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISN 141
+ YY + +W C + +F +N S+ FL V+ +R+ V P +
Sbjct: 72 LWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTR 131
Query: 142 WTAAIISCLLWGITVGLTVHLL----KKKLLIQNGTANVCISFS----------ICHTFR 187
+S ++W VG + L + G+ NV F I H F
Sbjct: 132 KRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIF- 190
Query: 188 WHEAMFLLEFFLPLGIILFCSARIIWSLRQR--QMDRHAKIK-RAITFIMVVAIVFVICF 244
+ FFL IILFC+ II +L + Q R+A++K RA+ + V VF+ICF
Sbjct: 191 -----IVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICF 245
Query: 245 LPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF--- 301
+P VV++ W L G Q+ + +++++ A +TL N +LDPV+Y F + F
Sbjct: 246 VPHHVVQLP--WTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKH 303
Query: 302 --PNFFSTLINRCLQRKIT 318
F+S +R R T
Sbjct: 304 LTEKFYSMRSSRKCSRATT 322
>gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 123 bits (308), Expect = 3e-28
Identities = 86/297 (28%), Positives = 132/297 (44%), Gaps = 20/297 (6%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L
Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ Y + W FGD CRLV F+F N GSI+FLT ++ RY + HP +K
Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNG---TANVCISFS----ICHTFRWHEA 191
AA + C+ + + +T L + G VC S H + A
Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195
Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244
+ ++ F LP +L C + L ++ +R K R +VVA F I F
Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252
Query: 245 LPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
LP + + + T G C V + A+ T F NS+LDP+++YF+ F
Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308
>gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 123 bits (308), Expect = 3e-28
Identities = 86/297 (28%), Positives = 132/297 (44%), Gaps = 20/297 (6%)
Query: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L
Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77
Query: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
LP ++ Y + W FGD CRLV F+F N GSI+FLT ++ RY + HP +K
Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137
Query: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNG---TANVCISFS----ICHTFRWHEA 191
AA + C+ + + +T L + G VC S H + A
Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195
Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244
+ ++ F LP +L C + L ++ +R K R +VVA F I F
Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252
Query: 245 LPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
LP + + + T G C V + A+ T F NS+LDP+++YF+ F
Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.143 0.471
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,863,699
Number of Sequences: 37866
Number of extensions: 636759
Number of successful extensions: 3031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 2084
Number of HSP's gapped (non-prelim): 569
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.