Search of human proteins with 157676340

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157676340 zinc finger protein 142 [Homo sapiens]
         (1687 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157676340 zinc finger protein 142 [Homo sapiens]                  3623   0.0  
gi|210031219 zinc finger protein 845 [Homo sapiens]                   239   2e-62
gi|55769537 zinc finger protein 658 [Homo sapiens]                    238   5e-62
gi|156547246 zinc finger protein 160 [Homo sapiens]                   236   1e-61
gi|38788302 zinc finger protein 160 [Homo sapiens]                    236   1e-61
gi|38788288 zinc finger protein 160 [Homo sapiens]                    236   1e-61
gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]          231   4e-60
gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]         231   4e-60
gi|22095393 zinc finger protein 420 [Homo sapiens]                    231   6e-60
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor...   231   6e-60
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor...   231   6e-60
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor...   231   6e-60
gi|188497655 zinc finger protein 84 [Homo sapiens]                    231   6e-60
gi|188497653 zinc finger protein 84 [Homo sapiens]                    231   6e-60
gi|34419633 zinc finger protein 135 [Homo sapiens]                    228   5e-59
gi|154091003 zinc finger protein 470 [Homo sapiens]                   227   8e-59
gi|157167158 zinc finger protein 808 [Homo sapiens]                   227   8e-59
gi|48717241 zinc finger protein 425 [Homo sapiens]                    226   1e-58
gi|40217792 zinc finger protein 585A [Homo sapiens]                   226   1e-58
gi|22749331 zinc finger protein 585A [Homo sapiens]                   226   1e-58
gi|169213999 PREDICTED: similar to hCG1778601 isoform 1 [Homo sa...   226   2e-58
gi|169214410 PREDICTED: similar to hCG1778601 isoform 1 [Homo sa...   226   2e-58
gi|169213416 PREDICTED: hypothetical protein LOC388559 [Homo sap...   226   2e-58
gi|194018469 zinc finger protein 546 [Homo sapiens]                   226   2e-58
gi|134254457 zinc finger protein 665 [Homo sapiens]                   225   2e-58
gi|25014093 zinc finger protein 585B [Homo sapiens]                   225   3e-58
gi|24307875 zinc finger protein 33B [Homo sapiens]                    223   9e-58
gi|153792259 zinc finger protein 778 [Homo sapiens]                   223   1e-57
gi|209954795 zinc finger protein 761 [Homo sapiens]                   222   2e-57
gi|172072608 zinc finger protein 624 [Homo sapiens]                   222   2e-57

>gi|157676340 zinc finger protein 142 [Homo sapiens]
          Length = 1687

 Score = 3623 bits (9396), Expect = 0.0
 Identities = 1687/1687 (100%), Positives = 1687/1687 (100%)

Query: 1    MTDPLLDSQPASSTGEMDGLCPELLLIPPPLSNRGILGPVQSPCPSRDPAPIPTEPGCLL 60
            MTDPLLDSQPASSTGEMDGLCPELLLIPPPLSNRGILGPVQSPCPSRDPAPIPTEPGCLL
Sbjct: 1    MTDPLLDSQPASSTGEMDGLCPELLLIPPPLSNRGILGPVQSPCPSRDPAPIPTEPGCLL 60

Query: 61   VEATATEEGPGNMEIIVETVAGTLTPGAPGETPAPKLPPGEREPSQEAGTPLPGQETAEE 120
            VEATATEEGPGNMEIIVETVAGTLTPGAPGETPAPKLPPGEREPSQEAGTPLPGQETAEE
Sbjct: 61   VEATATEEGPGNMEIIVETVAGTLTPGAPGETPAPKLPPGEREPSQEAGTPLPGQETAEE 120

Query: 121  ENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVE 180
            ENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVE
Sbjct: 121  ENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVE 180

Query: 181  HLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMAS 240
            HLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMAS
Sbjct: 181  HLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMAS 240

Query: 241  MHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDR 300
            MHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDR
Sbjct: 241  MHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDR 300

Query: 301  KAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRK 360
            KAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRK
Sbjct: 301  KAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRK 360

Query: 361  HKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHM 420
            HKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHM
Sbjct: 361  HKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHM 420

Query: 421  LLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHA 480
            LLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHA
Sbjct: 421  LLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHA 480

Query: 481  GDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTP 540
            GDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTP
Sbjct: 481  GDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTP 540

Query: 541  APLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            APLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP
Sbjct: 541  APLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600

Query: 601  GDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLSARPEGPGHEPGTVVDPSLDQALPEMS 660
            GDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLSARPEGPGHEPGTVVDPSLDQALPEMS
Sbjct: 601  GDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLSARPEGPGHEPGTVVDPSLDQALPEMS 660

Query: 661  EEVNTGRQEGSEAPHGGDLGGSPSPAEVEEGSCTLHLEALGVELESVTEPPLEEVTETAP 720
            EEVNTGRQEGSEAPHGGDLGGSPSPAEVEEGSCTLHLEALGVELESVTEPPLEEVTETAP
Sbjct: 661  EEVNTGRQEGSEAPHGGDLGGSPSPAEVEEGSCTLHLEALGVELESVTEPPLEEVTETAP 720

Query: 721  MEFRPLGLEGPDGLEGPELSSFEGIGTSDLSAEENPLLEKPVSEPSTNPPSLEEAPNNWV 780
            MEFRPLGLEGPDGLEGPELSSFEGIGTSDLSAEENPLLEKPVSEPSTNPPSLEEAPNNWV
Sbjct: 721  MEFRPLGLEGPDGLEGPELSSFEGIGTSDLSAEENPLLEKPVSEPSTNPPSLEEAPNNWV 780

Query: 781  GTFKTTPPAETAPLPPLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPH 840
            GTFKTTPPAETAPLPPLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPH
Sbjct: 781  GTFKTTPPAETAPLPPLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPH 840

Query: 841  CPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLP 900
            CPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLP
Sbjct: 841  CPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLP 900

Query: 901  RPDSPIPLQPVLPGTQASEDTESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVS 960
            RPDSPIPLQPVLPGTQASEDTESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVS
Sbjct: 901  RPDSPIPLQPVLPGTQASEDTESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVS 960

Query: 961  GSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHR 1020
            GSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHR
Sbjct: 961  GSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHR 1020

Query: 1021 FEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPK 1080
            FEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPK
Sbjct: 1021 FEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPK 1080

Query: 1081 NGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLC 1140
            NGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLC
Sbjct: 1081 NGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLC 1140

Query: 1141 PFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPH 1200
            PFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPH
Sbjct: 1141 PFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPH 1200

Query: 1201 QCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCP 1260
            QCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCP
Sbjct: 1201 QCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCP 1260

Query: 1261 LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSP 1320
            LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSP
Sbjct: 1261 LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSP 1320

Query: 1321 AETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSH 1380
            AETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSH
Sbjct: 1321 AETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSH 1380

Query: 1381 RCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLD 1440
            RCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLD
Sbjct: 1381 RCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLD 1440

Query: 1441 HHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMR 1500
            HHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMR
Sbjct: 1441 HHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMR 1500

Query: 1501 IHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHR 1560
            IHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHR
Sbjct: 1501 IHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHR 1560

Query: 1561 EARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHP 1620
            EARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHP
Sbjct: 1561 EARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHP 1620

Query: 1621 FFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPSPPAPAA 1680
            FFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPSPPAPAA
Sbjct: 1621 FFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPSPPAPAA 1680

Query: 1681 PHTGPEG 1687
            PHTGPEG
Sbjct: 1681 PHTGPEG 1687


>gi|210031219 zinc finger protein 845 [Homo sapiens]
          Length = 970

 Score =  239 bits (609), Expect = 2e-62
 Identities = 166/559 (29%), Positives = 235/559 (42%), Gaps = 51/559 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH--CSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  QE  L  H         +GE H  CS C  T    +AL +H+       
Sbjct: 271  YKCNDCGKTFSQELTLTCHHRL-----HTGEKHYKCSECGKTFSRNSALVIHK------- 318

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
            A   G + + +C +CG T  Q+  +  HRRL H G KP++C  CD + + +  LE H+  
Sbjct: 319  AIHTGEKSY-KCNECGKTFSQTSYLVYHRRL-HTGEKPYKCEECDKAFSFKSNLERHRKI 376

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C+ C +TF   S L  HR R+H     + C  C  +      +  H    H 
Sbjct: 377  HTGEKPYKCNECSRTFSRKSSLTRHR-RLHTGEKPYKCNDCGKTFSQMSSLVYH-RRLHT 434

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C+  FS ++ L++H  R H             T E P  C+ CG      +
Sbjct: 435  GEKPYKCEECDEAFSFKSNLERHR-RIH-------------TGEKPYKCNDCGKTFSQTS 480

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVK 1397
            SL  H R        +C  C EAF  +  L+ HR        ++C  C      +  L +
Sbjct: 481  SLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTR 540

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPL-------------HCPFCDFTCRHQLVLDHHVK 1444
            H    H           G    GQ  L              C  C     +   + +H +
Sbjct: 541  H-CRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWR 599

Query: 1445 GHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKE 1504
             H   R YKC  C    ++R  +  H R H+GEKPY C  C  A +  S L+ H RIH  
Sbjct: 600  IHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTG 659

Query: 1505 ERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARA 1564
            E+ Y C ECG      + L  H   HTG KPY+C EC     R  AL +H+   H   + 
Sbjct: 660  EKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIHKAI-HTGEKP 718

Query: 1565 FMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCR 1624
            + C +CGKAF  +  L  HLR H+  KPY C  C + F   + L  H   HT   P+ C+
Sbjct: 719  YKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCK 778

Query: 1625 LCNYKAKQKFQVVKHVRRH 1643
            +C+    +   + +H R H
Sbjct: 779  VCDKAFGRDSHLAQHTRIH 797



 Score =  239 bits (609), Expect = 2e-62
 Identities = 160/538 (29%), Positives = 228/538 (42%), Gaps = 72/538 (13%)

Query: 1137 CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEG 1196
            C+ C  T    ++L  H +R H       G +P+ +C DCG T  Q   +  HRRL H G
Sbjct: 385  CNECSRTFSRKSSLTRH-RRLHT------GEKPY-KCNDCGKTFSQMSSLVYHRRL-HTG 435

Query: 1197 VKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPT 1256
             KP++C  CD + + +  LE H+  HTG     C+ C +TF   S L  HR R+H     
Sbjct: 436  EKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHR-RLHTGEKP 494

Query: 1257 HFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPA 1316
            + C  CD +   + ++ RH    H G   + C++C   FS +++L +H  R H       
Sbjct: 495  YKCEECDEAFSFKSNLERH-RIIHTGEKLYKCNECGKTFSRKSSLTRHC-RLH------- 545

Query: 1317 PGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQH--PRLECGACQEAFPSRLALDEHRR 1374
                  T E P  C+ CG      ++L  H          +C  C + F +   +  H R
Sbjct: 546  ------TGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWR 599

Query: 1375 --QQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFT 1432
               +  S++C  C    R R      YL  H  T +           G+ P  C  CD  
Sbjct: 600  IHNEERSYKCNRCGKFFRHR-----SYLAVHWRTHS-----------GEKPYKCEECDEA 643

Query: 1433 CRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADP 1492
               +  L  H + H G + Y+C +C  +   +  +T H R+HTGEKPY C+ C       
Sbjct: 644  FSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFGRN 703

Query: 1493 SRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALR 1552
            S L  H  IH  E+ Y C ECG      + L  H+  HTG KPY+C EC+   +R  +L 
Sbjct: 704  SALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLE 763

Query: 1553 VH--------------------------QETR-HREARAFMCEQCGKAFKTRFLLRTHLR 1585
             H                          Q TR H   + + C +CGK F+    L  H  
Sbjct: 764  KHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKA 823

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             HS  KPY CN C + FR  + L  H   HT   P+ C  C     +K  + +H R H
Sbjct: 824  IHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLH 881



 Score =  224 bits (571), Expect = 5e-58
 Identities = 151/531 (28%), Positives = 210/531 (39%), Gaps = 92/531 (17%)

Query: 1172 QCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCS 1231
            +C  CG    Q R +  HRR  H G KP++C  C  + ++   L  H   HTG     CS
Sbjct: 244  KCDVCGKVFNQKRYLACHRRC-HTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCS 302

Query: 1232 SCPQTFGTNSKLRLHRL---------------------------RVHDKTPTHFCPLCDY 1264
             C +TF  NS L +H+                            R+H     + C  CD 
Sbjct: 303  ECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDK 362

Query: 1265 SGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETT 1324
            +   + ++ RH    H G   + C++C   FS +++L +H  R H             T 
Sbjct: 363  AFSFKSNLERH-RKIHTGEKPYKCNECSRTFSRKSSLTRHR-RLH-------------TG 407

Query: 1325 EGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRR--QQHFSH 1380
            E P  C+ CG      +SL  H R        +C  C EAF  +  L+ HRR       +
Sbjct: 408  EKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPY 467

Query: 1381 RCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLD 1440
            +C  C     +   LV H                     G+ P  C  CD     +  L+
Sbjct: 468  KCNDCGKTFSQTSSLVYHRRLH----------------TGEKPYKCEECDEAFSFKSNLE 511

Query: 1441 HHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHM- 1499
             H   H G +LYKC +C  +   +  +T H R+HTGEKPY C+ C  A    S L YH  
Sbjct: 512  RHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQA 571

Query: 1500 ---------------------------RIHKEERKYLCPECGYKCKWVNQLKYHMTKHTG 1532
                                       RIH EER Y C  CG   +  + L  H   H+G
Sbjct: 572  IHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSG 631

Query: 1533 LKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKP 1592
             KPY+C EC+   +    L+ H+   H   + + C +CGK F  +  L  H R H+  KP
Sbjct: 632  EKPYKCEECDEAFSFKSNLQRHRRI-HTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKP 690

Query: 1593 YVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            Y CN C + F   + L  H   HT   P+ C  C     QK  +  H+R H
Sbjct: 691  YKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLH 741



 Score =  216 bits (550), Expect = 1e-55
 Identities = 156/522 (29%), Positives = 211/522 (40%), Gaps = 63/522 (12%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P+ +C DCG T  Q+  +  HRRL H G KP++C  CD + + +  LE H+  HTG 
Sbjct: 463  GEKPY-KCNDCGKTFSQTSSLVYHRRL-HTGEKPYKCEECDEAFSFKSNLERHRIIHTGE 520

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C +TF   S L  H  R+H     + C  C  +   +  +  H  + H     
Sbjct: 521  KLYKCNECGKTFSRKSSLTRH-CRLHTGEKPYQCNECGKAFRGQSALIYH-QAIHGIGKL 578

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            + C+ C   FS+ T +  H  R H E             E    C+RCG      + L  
Sbjct: 579  YKCNDCHQVFSNATTIANH-WRIHNE-------------ERSYKCNRCGKFFRHRSYLAV 624

Query: 1346 H--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHY-L 1400
            H  T       +C  C EAF  +  L  HRR       +RC  C      +  L  H  L
Sbjct: 625  HWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRL 684

Query: 1401 EQHEETSAAVAASDGDG-----------DAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGT 1449
               E+           G             G+ P  C  C      +  L  H++ H G 
Sbjct: 685  HTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGE 744

Query: 1450 RLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYL 1509
            + YKC +C      +  +  H RIHTGEKPY C +C  A    S L  H RIH  E+ Y 
Sbjct: 745  KPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK 804

Query: 1510 CPECG---------------------YKCKWVNQ-------LKYHMTKHTGLKPYQCPEC 1541
            C ECG                     YKC    +       L+ H   HTG KPY+C EC
Sbjct: 805  CNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSEC 864

Query: 1542 EYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRA 1601
                NR   L  H    H   + + C +CGK F  +  L  H R H+  KPY CN C + 
Sbjct: 865  GKVFNRKANLSRHHRL-HTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNECGKT 923

Query: 1602 FRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            FR  + L  H   HT   P+ C  C     +K ++ +H R H
Sbjct: 924  FRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIH 965



 Score =  211 bits (538), Expect = 4e-54
 Identities = 143/504 (28%), Positives = 197/504 (39%), Gaps = 66/504 (13%)

Query: 1172 QCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCS 1231
            QC + G     S  +++H+ + H G K ++C  C     ++  L  H+  HTG     C+
Sbjct: 216  QCNESGKAFNYSSVLRKHQII-HLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKPYKCN 274

Query: 1232 SCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQC 1291
             C +TF     L  H  R+H     + C  C  +      +  H  + H G  ++ C++C
Sbjct: 275  DCGKTFSQELTLTCHH-RLHTGEKHYKCSECGKTFSRNSALVIH-KAIHTGEKSYKCNEC 332

Query: 1292 EAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQH 1351
               FS  + L  H  R H             T E P  C  C       ++L  H RK H
Sbjct: 333  GKTFSQTSYLVYHR-RLH-------------TGEKPYKCEECDKAFSFKSNLERH-RKIH 377

Query: 1352 ---PRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEET 1406
                  +C  C   F  + +L  HRR       ++C  C     +   LV H        
Sbjct: 378  TGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLH---- 433

Query: 1407 SAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQK 1466
                         G+ P  C  CD     +  L+ H + H G + YKC DC  +      
Sbjct: 434  ------------TGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSS 481

Query: 1467 ITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYH 1526
            + +H R+HTGEKPY C  C  A +  S L+ H  IH  E+ Y C ECG      + L  H
Sbjct: 482  LVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRH 541

Query: 1527 MTKHTGLKPYQCPECEYCTNRADALRVHQETR---------------------------H 1559
               HTG KPYQC EC        AL  HQ                              H
Sbjct: 542  CRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIH 601

Query: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRH 1619
             E R++ C +CGK F+ R  L  H R HS  KPY C  C  AF + + L+ H   HT   
Sbjct: 602  NEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEK 661

Query: 1620 PFFCRLCNYKAKQKFQVVKHVRRH 1643
            P+ C  C     +K  +  H R H
Sbjct: 662  PYRCNECGKTFSRKSYLTCHRRLH 685



 Score =  190 bits (482), Expect = 1e-47
 Identities = 128/446 (28%), Positives = 181/446 (40%), Gaps = 37/446 (8%)

Query: 1215 LEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITR 1274
            L   Q  H       C+   + F  +S LR H++ +H     + C +C      +  +  
Sbjct: 202  LTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQI-IHLGAKQYKCDVCGKVFNQKRYLAC 260

Query: 1275 HVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCG 1334
            H   CH G   + C+ C   FS E  L  H  R H             T E    CS CG
Sbjct: 261  H-RRCHTGKKPYKCNDCGKTFSQELTLTCHH-RLH-------------TGEKHYKCSECG 305

Query: 1335 LLCPSPASLRGHT--RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAAR 1390
                  ++L  H          +C  C + F     L  HRR       ++C+ CD A  
Sbjct: 306  KTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFS 365

Query: 1391 ERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTR 1450
                  K  LE+H +              G+ P  C  C  T   +  L  H + H G +
Sbjct: 366  -----FKSNLERHRKIHT-----------GEKPYKCNECSRTFSRKSSLTRHRRLHTGEK 409

Query: 1451 LYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLC 1510
             YKC DC  +      + +H R+HTGEKPY C  C  A +  S L+ H RIH  E+ Y C
Sbjct: 410  PYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKC 469

Query: 1511 PECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQC 1570
             +CG      + L YH   HTG KPY+C EC+   +    L  H+   H   + + C +C
Sbjct: 470  NDCGKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHR-IIHTGEKLYKCNEC 528

Query: 1571 GKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKA 1630
            GK F  +  L  H R H+  KPY CN C +AFR  + L +H   H     + C  C+   
Sbjct: 529  GKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVF 588

Query: 1631 KQKFQVVKHVRRHHPDQADPNQGVGK 1656
                 +  H R H+ +++      GK
Sbjct: 589  SNATTIANHWRIHNEERSYKCNRCGK 614



 Score =  176 bits (447), Expect = 1e-43
 Identities = 134/494 (27%), Positives = 192/494 (38%), Gaps = 53/494 (10%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  ++ +L  H    C L  +GE    C+ C       +AL  HQ       
Sbjct: 523  YKCNECGKTFSRKSSLTRH----CRLH-TGEKPYQCNECGKAFRGQSALIYHQA------ 571

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G     +C DC      +  +  H R+ H   + ++C  C      R  L  H   
Sbjct: 572  --IHGIGKLYKCNDCHQVFSNATTIANHWRI-HNEERSYKCNRCGKFFRHRSYLAVHWRT 628

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            H+G     C  C + F   S L+ HR R+H     + C  C  +   +  +T H    H 
Sbjct: 629  HSGEKPYKCEECDEAFSFKSNLQRHR-RIHTGEKPYRCNECGKTFSRKSYLTCH-RRLHT 686

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C++C   F   +AL  H                  T E P  C+ CG      +
Sbjct: 687  GEKPYKCNECGKTFGRNSALIIH--------------KAIHTGEKPYKCNECGKAFSQKS 732

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
            SL  H R        +C  C + F  + +L++HRR       ++C++CD A     G   
Sbjct: 733  SLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKA----FGRDS 788

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H L QH                G+ P  C  C    RH   L  H   H G + YKC +C
Sbjct: 789  H-LAQHTRIHT-----------GEKPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNEC 836

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              + ++   +  H  IHTGEKPY C  C       + L  H R+H  E+ Y C +CG   
Sbjct: 837  GKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVF 896

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
                 L  H   HTG KPY+C EC         L +H+ T H   + + C +CGK F  +
Sbjct: 897  NQQAHLACHHRIHTGEKPYKCNECGKTFRHNSVLVIHK-TIHTGEKPYKCNECGKVFNRK 955

Query: 1578 FLLRTHLRKHSEAK 1591
              L  H R H+  K
Sbjct: 956  AKLARHHRIHTGKK 969



 Score =  174 bits (442), Expect = 5e-43
 Identities = 133/469 (28%), Positives = 192/469 (40%), Gaps = 62/469 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH-CSLCPFTAPAATAL----RLHQKRRH 1158
            + C  C  + + + AL  HQ     +   G+L+ C+ C      AT +    R+H + R 
Sbjct: 551  YQCNECGKAFRGQSALIYHQA----IHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERS 606

Query: 1159 PTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAH 1218
                         +C  CG   +    +  H R  H G KP++C  CD + + +  L+ H
Sbjct: 607  ------------YKCNRCGKFFRHRSYLAVHWRT-HSGEKPYKCEECDEAFSFKSNLQRH 653

Query: 1219 QSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNS 1278
            +  HTG     C+ C +TF   S L  HR R+H     + C  C  +      +  H  +
Sbjct: 654  RRIHTGEKPYRCNECGKTFSRKSYLTCHR-RLHTGEKPYKCNECGKTFGRNSALIIH-KA 711

Query: 1279 CHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCP 1338
             H G   + C++C   FS +++L  H LR H             T E P  C  C  +  
Sbjct: 712  IHTGEKPYKCNECGKAFSQKSSLTCH-LRLH-------------TGEKPYKCEECDKVFS 757

Query: 1339 SPASLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVG 1394
              +SL  H R        +C  C +AF     L +H R       ++C  C    R    
Sbjct: 758  RKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSA 817

Query: 1395 LVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKC 1454
            LV H                    +G+ P  C  C  T RH   L+ H   H G + YKC
Sbjct: 818  LVIHKAIH----------------SGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKC 861

Query: 1455 TDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECG 1514
            ++C      +  ++ H R+HTGEKPY C+ C       + L  H RIH  E+ Y C ECG
Sbjct: 862  SECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNECG 921

Query: 1515 YKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADAL----RVHQETRH 1559
               +  + L  H T HTG KPY+C EC    NR   L    R+H   +H
Sbjct: 922  KTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKKH 970



 Score =  172 bits (436), Expect = 2e-42
 Identities = 121/444 (27%), Positives = 182/444 (40%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F +++ L  H  LH  +   QC  C K F  +S L  H       K + 
Sbjct: 521 KLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYK 580

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  CH        +  H    +E+ S      Y C  C + FR    L  H ++H+    
Sbjct: 581 CNDCHQVFSNATTIANHWRIHNEERS------YKCNRCGKFFRHRSYLAVHWRTHSGEK- 633

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C  E C  A   +    +H +   G +   C  + C   F+    +  H + H
Sbjct: 634 ----PYKC--EECDEAFSFKSNLQRHRRIHTGEKPYRC--NECGKTFSRKSYLTCHRRLH 685

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C            HK   H G +  +C  C  A     +   H+ ++H  
Sbjct: 686 TGEKPYKCNECGKTFGRNSALIIHKAI-HTGEKPYKCNECGKAFSQKSSLTCHL-RLHTG 743

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC+   + K  L +H  +HTGEKP+KC++CD      S+L++H   H+  K Y
Sbjct: 744 EKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPY 803

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG   +    L +H   H+G+  Y+CN+C         L  HK  H G K   C  
Sbjct: 804 KCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSE 863

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     RK  L +H    H   T    Y C+ C  +  ++QA L+  +  HT  + + C 
Sbjct: 864 CGKVFNRKANLSRH----HRLHTGEKPYKCNKCG-KVFNQQAHLACHHRIHTGEKPYKCN 918

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C      N+ L+ HK    G  P
Sbjct: 919 ECGKTFRHNSVLVIHKTIHTGEKP 942



 Score =  167 bits (423), Expect = 8e-41
 Identities = 127/472 (26%), Positives = 191/472 (40%), Gaps = 54/472 (11%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +   L  H  LH  +   +C  C K F+  S L  H     GEK++ 
Sbjct: 269 KPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYK 328

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  + + L  H   +H          Y C  C + F     L+ H K HT    
Sbjct: 329 CNECGKTFSQTSYLVYHRR-LHTG-----EKPYKCEECDKAFSFKSNLERHRKIHTGEK- 381

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  CS     + +  +H +   G +  +C  + C   F+   ++  H + H
Sbjct: 382 ----PYKCNE--CSRTFSRKSSLTRHRRLHTGEKPYKC--NDCGKTFSQMSSLVYHRRLH 433

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD A S K    +H++  H G +  +C  C   TF+  +   +  ++H  
Sbjct: 434 TGEKPYKCEECDEAFSFKSNLERHRRI-HTGEKPYKCNDCG-KTFSQTSSLVYHRRLHTG 491

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC+ A + K  L RH ++HTGEK +KC  C  T    S L++H   H+  K Y
Sbjct: 492 EKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPY 551

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC---------------------SYRCHR 496
            C ECG   + +  L  H   H     Y+CN C                     SY+C+R
Sbjct: 552 QCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERSYKCNR 611

Query: 497 ADQ-------LSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHY 548
             +       L+ H   H G K   CE C  A   K  LQ+H   + H G     Y C+ 
Sbjct: 612 CGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRH--RRIHTGEKP--YRCNE 667

Query: 549 CSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           C      K  +  H    HT  + + C  C      N+ L+ HK    G  P
Sbjct: 668 CGKTFSRKSYLTCHRRL-HTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKP 718



 Score =  149 bits (376), Expect = 2e-35
 Identities = 102/358 (28%), Positives = 148/358 (41%), Gaps = 20/358 (5%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T S  K + C EC   F  +++L  H  +H  +   +C  C K F+ KS L  H     G
Sbjct: 628 THSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTG 687

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           EK + C  C  +    +AL  H A +H          Y C  C + F    +L  HL+ H
Sbjct: 688 EKPYKCNECGKTFGRNSALIIHKA-IHTG-----EKPYKCNECGKAFSQKSSLTCHLRLH 741

Query: 276 TAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEA 335
           T        P +C  E C      + +  KH +   G +  +C+   C   F     +  
Sbjct: 742 TGEK-----PYKC--EECDKVFSRKSSLEKHRRIHTGEKPYKCK--VCDKAFGRDSHLAQ 792

Query: 336 HHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVG 392
           H + H     + C  C     +      HK   H G +  +C  C     +  A + H  
Sbjct: 793 HTRIHTGEKPYKCNECGKNFRHNSALVIHKAI-HSGEKPYKCNECGKTFRHNSALEIHKA 851

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
            +H  EK ++C EC      K  L RH  LHTGEKP+KC  C       ++L+ H   H+
Sbjct: 852 -IHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHT 910

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
             K Y C ECG   +    L +H   H G+  Y+CN+C    +R  +L+ H   H GK
Sbjct: 911 GEKPYKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGK 968



 Score =  147 bits (372), Expect = 7e-35
 Identities = 115/442 (26%), Positives = 170/442 (38%), Gaps = 57/442 (12%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           KTH+       F   + L +   +H  + S QC    K F   S L+ H +  LG K + 
Sbjct: 185 KTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYK 244

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C +C     ++  L  H         +     Y C  C + F     L  H + HT    
Sbjct: 245 CDVCGKVFNQKRYLACHRRC------HTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKH 298

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
                 +C + G +++     A + H     G ++ +C  + C   F+    +  H + H
Sbjct: 299 -----YKCSECGKTFSR--NSALVIHKAIHTGEKSYKC--NECGKTFSQTSYLVYHRRLH 349

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD A S K    +H+K                              +H  
Sbjct: 350 TGEKPYKCEECDKAFSFKSNLERHRK------------------------------IHTG 379

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC+   + K  L RH  LHTGEKP+KC  C  T   +S L  H   H+  K Y
Sbjct: 380 EKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPY 439

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C EC     +K  L  H R H G+  Y+CN C     +   L  H+  H G K   CE 
Sbjct: 440 KCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHTGEKPYKCEE 499

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCK-HTRLREFHC 575
           C  A   K  L++H        T   LY C+ C      K ++  H  C+ HT  + + C
Sbjct: 500 CDEAFSFKSNLERHRIIH----TGEKLYKCNECGKTFSRKSSLTRH--CRLHTGEKPYQC 553

Query: 576 ALCDYRTFSNTTLLFHKRKAHG 597
             C  + F   + L + +  HG
Sbjct: 554 NECG-KAFRGQSALIYHQAIHG 574



 Score =  123 bits (309), Expect = 1e-27
 Identities = 81/298 (27%), Positives = 126/298 (42%), Gaps = 20/298 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + + L+ H  +H  +   +C  C K F+ KS L  HL    GEK + 
Sbjct: 689 KPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYK 748

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C      +++L +H   +H          Y C VC + F     L +H + HT    
Sbjct: 749 CEECDKVFSRKSSLEKHRR-IHTG-----EKPYKCKVCDKAFGRDSHLAQHTRIHTGEK- 801

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C + G ++      A + H     G +  +C  + C   F    A+E H   H
Sbjct: 802 ----PYKCNECGKNFR--HNSALVIHKAIHSGEKPYKC--NECGKTFRHNSALEIHKAIH 853

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C    + K    +H +  H G +  +C  C    FN  A+     ++H  
Sbjct: 854 TGEKPYKCSECGKVFNRKANLSRHHRL-HTGEKPYKCNKCG-KVFNQQAHLACHHRIHTG 911

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
           EK ++C EC     H  VL+ H  +HTGEKP+KC  C       + L++H   H+  K
Sbjct: 912 EKPYKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKK 969



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 62/212 (29%), Positives = 87/212 (41%), Gaps = 35/212 (16%)

Query: 1463 NRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQ 1522
            N   +T    +H  EK + C+    A    S L+ H  IH   ++Y C  CG   K  NQ
Sbjct: 198  NSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCG---KVFNQ 254

Query: 1523 LKY---HMTKHTGLKPY----------------------------QCPECEYCTNRADAL 1551
             +Y   H   HTG KPY                            +C EC    +R  AL
Sbjct: 255  KRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSAL 314

Query: 1552 RVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHH 1611
             +H+   H   +++ C +CGK F     L  H R H+  KPY C  C +AF + + L  H
Sbjct: 315  VIHKAI-HTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERH 373

Query: 1612 ALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
               HT   P+ C  C+    +K  + +H R H
Sbjct: 374  RKIHTGEKPYKCNECSRTFSRKSSLTRHRRLH 405



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 1/104 (0%)

Query: 1540 ECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCH 1599
            + E   N A  +   Q    R  +  + +  G  F    LL      H   K + CN   
Sbjct: 163  QVEKSINSASLVSTSQRISCRP-KTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCNESG 221

Query: 1600 RAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            +AF +++ LR H + H     + C +C     QK  +  H R H
Sbjct: 222  KAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCH 265



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    + ++C  C  +  +++ L  H R  C   ++P  C +CG +F Q+  L+ H
Sbjct: 235 IIHLGAKQYKCDVCGKVFNQKRYLACHRR--CHTGKKPYKCNDCGKTFSQELTLTCH 289



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 6/54 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGLSTHL 885
           + ++C  C     R  AL +H    TG     +P  C ECG +F Q+  L+ HL
Sbjct: 689 KPYKCNECGKTFGRNSALIIHKAIHTG----EKPYKCNECGKAFSQKSSLTCHL 738



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGL 881
           +   +  GE + ++C  C    R   AL +H    TG     +P  C ECG  F ++  L
Sbjct: 820 IHKAIHSGE-KPYKCNECGKTFRHNSALEIHKAIHTG----EKPYKCSECGKVFNRKANL 874

Query: 882 STH 884
           S H
Sbjct: 875 SRH 877



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  +  R+  L+ H R  TG     +P  C +CG  F QQ  L+ H
Sbjct: 857 KPYKCSECGKVFNRKANLSRHHRLHTG----EKPYKCNKCGKVFNQQAHLACH 905


>gi|55769537 zinc finger protein 658 [Homo sapiens]
          Length = 1059

 Score =  238 bits (606), Expect = 5e-62
 Identities = 166/558 (29%), Positives = 229/558 (41%), Gaps = 78/558 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  S     ALR HQ        +GE    CS C  T    +ALR H +      
Sbjct: 574  YECNDCGKSFTYNSALRAHQ-----RIHTGEKPYECSDCEKTFAHNSALRAHHRIH---- 624

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG +      ++ H+R+ H G KP++C  C  S T    L AHQ  
Sbjct: 625  ---TGEKPY-ECNECGRSFAHISVLKAHQRI-HTGEKPYECNECGRSFTYNSALRAHQRI 679

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C +TF  NS L++H+ R+H     + C  C+ + +  +   R   + H 
Sbjct: 680  HTGRKPYECSDCEKTFAHNSALKIHQ-RIHTGEKPYECNECEKT-FAHNSALRAHQNIHT 737

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +T L  H  R H             T E P  CS+CG      +
Sbjct: 738  GEKLYECSECGKTFFQKTRLSTHR-RIH-------------TGEKPYECSKCGKTFSQKS 783

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHY 1399
             L GH R        EC  C + F  + AL  H+R                         
Sbjct: 784  YLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIH----------------------- 820

Query: 1400 LEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAY 1459
                                G+ P  C  C  T   +  L  H + H G + Y+C +C  
Sbjct: 821  -------------------TGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGK 861

Query: 1460 STKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            +  +   +  H RIHTGEKPY C+ C    +  S L+ H+R    E+ Y C ECG     
Sbjct: 862  TFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSE 921

Query: 1520 VNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFL 1579
             + +  H   HTG KPY+C  C         LRVHQ   H   +++ C  CGK F  +  
Sbjct: 922  KSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRI-HTGEKSYECNDCGKTFSQKSH 980

Query: 1580 LRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQV-VK 1638
            L  H R H+  KPY CN C +AF   + LR H   HT   P+ C  C     +K  + V 
Sbjct: 981  LSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVH 1040

Query: 1639 HVRRHHPDQADPNQGVGK 1656
            H R H  ++     G GK
Sbjct: 1041 HTRMHTREKTLACNGFGK 1058



 Score =  231 bits (588), Expect = 6e-60
 Identities = 148/497 (29%), Positives = 218/497 (43%), Gaps = 41/497 (8%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P+ +C +CG T  ++  ++ H+R+ H G KP++C  C+ + + +  L  HQ  HTG 
Sbjct: 514  GEKPY-ECIECGKTFSKTSHLRAHQRI-HTGEKPYECVECEKTFSHKTHLSVHQRVHTGE 571

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C ++F  NS LR H+ R+H     + C  C+ + +  +   R  +  H G   
Sbjct: 572  KPYECNDCGKSFTYNSALRAHQ-RIHTGEKPYECSDCEKT-FAHNSALRAHHRIHTGEKP 629

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            + C++C   F+  + LK H  R H             T E P  C+ CG      ++LR 
Sbjct: 630  YECNECGRSFAHISVLKAHQ-RIH-------------TGEKPYECNECGRSFTYNSALRA 675

Query: 1346 HTRKQHPR--LECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLE 1401
            H R    R   EC  C++ F    AL  H+R       + C  C+        L  H   
Sbjct: 676  HQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAH--- 732

Query: 1402 QHEETSAAVAASDGDGDA---------------GQPPLHCPFCDFTCRHQLVLDHHVKGH 1446
            Q+  T   +      G                 G+ P  C  C  T   +  L  H + H
Sbjct: 733  QNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIH 792

Query: 1447 GGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEER 1506
             G + Y+C  C  +   +  +  H RIHTGEKPY C+ C    +  + L  H RIH  E+
Sbjct: 793  TGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEK 852

Query: 1507 KYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFM 1566
             Y C ECG      + L+ H   HTG KPY+C +C    ++   LR H  TR  E + + 
Sbjct: 853  PYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGE-KPYE 911

Query: 1567 CEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLC 1626
            C +CGK F  +  +  H R H+  KPY CNVC + F   + LR H   HT    + C  C
Sbjct: 912  CSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDC 971

Query: 1627 NYKAKQKFQVVKHVRRH 1643
                 QK  +  H R H
Sbjct: 972  GKTFSQKSHLSAHQRIH 988



 Score =  182 bits (462), Expect = 2e-45
 Identities = 143/499 (28%), Positives = 192/499 (38%), Gaps = 66/499 (13%)

Query: 1174 GDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSC 1233
            G C  +  +   + QH+R  H G K +Q   C  S         H   + G     C+ C
Sbjct: 387  GKCRKSFYRKAHLIQHQR-PHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNEC 445

Query: 1234 PQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEA 1293
             + F  NS L  H LR+H K        CD +G  R   +  +   HQ T A    + E 
Sbjct: 446  GKAFCQNSNLSKH-LRIHTKEKP-----CDNNGCGRSYKSPLIG--HQKTDA----EMEL 493

Query: 1294 QFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--H 1351
               SE     H L+ H               E P  C  CG      + LR H R     
Sbjct: 494  CGGSEYGKTSH-LKGHQRILMG---------EKPYECIECGKTFSKTSHLRAHQRIHTGE 543

Query: 1352 PRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVA 1411
               EC  C++ F  +  L  H+R  H   +   C+   +         L  H+       
Sbjct: 544  KPYECVECEKTFSHKTHLSVHQRV-HTGEKPYECNDCGKSFT--YNSALRAHQRIHT--- 597

Query: 1412 ASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHS 1471
                    G+ P  C  C+ T  H   L  H + H G + Y+C +C  S  +   +  H 
Sbjct: 598  --------GEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQ 649

Query: 1472 RIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHT 1531
            RIHTGEKPY C+ C  +    S L+ H RIH   + Y C +C       + LK H   HT
Sbjct: 650  RIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHT 709

Query: 1532 GLKPYQCPECEYCTNRADALRVHQ--------------------ETR-------HREARA 1564
            G KPY+C ECE       ALR HQ                    +TR       H   + 
Sbjct: 710  GEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKP 769

Query: 1565 FMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCR 1624
            + C +CGK F  +  L  H R H+  KPY CNVC + F + A L  H   HT   P+ C 
Sbjct: 770  YECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECN 829

Query: 1625 LCNYKAKQKFQVVKHVRRH 1643
             C     Q+  +  H R H
Sbjct: 830  QCGKTFSQRTHLCAHQRIH 848



 Score =  182 bits (462), Expect = 2e-45
 Identities = 128/462 (27%), Positives = 189/462 (40%), Gaps = 48/462 (10%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F K +HL  H  +H  +   +C  C+K F+ K+ L  H     GEK + 
Sbjct: 516 KPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYE 575

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  S    +AL  H   +H          Y C  C + F  + AL+ H + HT    
Sbjct: 576 CNDCGKSFTYNSALRAHQR-IHTG-----EKPYECSDCEKTFAHNSALRAHHRIHTGEK- 628

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAHHKS 339
               P  C + G S+A     + +K  +  H G +  EC  + C   F    A+ AH + 
Sbjct: 629 ----PYECNECGRSFA---HISVLKAHQRIHTGEKPYEC--NECGRSFTYNSALRAHQRI 679

Query: 340 HYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHA 396
           H     + C  C+   ++    + H++  H G +   C  C     +  A + H   +H 
Sbjct: 680 HTGRKPYECSDCEKTFAHNSALKIHQRI-HTGEKPYECNECEKTFAHNSALRAHQN-IHT 737

Query: 397 HEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKD 456
            EK+++C EC      K  L  H  +HTGEKP++C  C  T    SYLS H   H+  K 
Sbjct: 738 GEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKP 797

Query: 457 YMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCE 515
           Y C  CG    +K  L VH R H G+  Y+CNQC     +   L +H+  H G K   C 
Sbjct: 798 YECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECN 857

Query: 516 VC--AFA----------------------CKRKYELQKHMASQHHPGTPAPLYPCHYCSY 551
            C   FA                      C + +    H+ +     +    Y C  C  
Sbjct: 858 ECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGK 917

Query: 552 QSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKR 593
               K  V +H+   HT  + + C +C      N+TL  H+R
Sbjct: 918 TFSEKSYVSAHQRV-HTGEKPYECNVCGKPFAHNSTLRVHQR 958



 Score =  173 bits (438), Expect = 1e-42
 Identities = 130/495 (26%), Positives = 186/495 (37%), Gaps = 72/495 (14%)

Query: 161  KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
            K + C EC++ F  +THL  H  +H  +   +C +C K FT  S L+ H     GEK + 
Sbjct: 544  KPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYE 603

Query: 221  CPLCHYSAVERNALNRH-----------------------MASMHEDISNFYSDTYACPV 257
            C  C  +    +AL  H                       +   H+ I       Y C  
Sbjct: 604  CSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTG-EKPYECNE 662

Query: 258  CREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVE 317
            C   F  + AL+ H + HT        P  C    C        A   H +   G +  E
Sbjct: 663  CGRSFTYNSALRAHQRIHTGRK-----PYEC--SDCEKTFAHNSALKIHQRIHTGEKPYE 715

Query: 318  CRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRC 374
            C  + C   FA   A+ AH   H     + C  C      K     H++  H G +   C
Sbjct: 716  C--NECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRI-HTGEKPYEC 772

Query: 375  TFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELC 434
            + C   TF+  +Y     ++H  EK ++C  C     +K  LI H  +HTGEKP++C  C
Sbjct: 773  SKCG-KTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQC 831

Query: 435  DFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCS--- 491
              T    ++L  H   H+  K Y C ECG        LR H R H G+  Y+CN C    
Sbjct: 832  GKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTF 891

Query: 492  ------------------YRCHRADQ-------LSSHKLRHQG-KSLMCEVCAFACKRKY 525
                              Y C    +       +S+H+  H G K   C VC        
Sbjct: 892  SKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNS 951

Query: 526  ELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSN 585
             L+ H   + H G  +  Y C+ C      K  + +H+   HT  + + C  C      N
Sbjct: 952  TLRVHQ--RIHTGEKS--YECNDCGKTFSQKSHLSAHQRI-HTGEKPYECNECGKAFAQN 1006

Query: 586  TTLLFHKRKAHGYVP 600
            +TL  H+R   G  P
Sbjct: 1007 STLRVHQRIHTGEKP 1021



 Score =  162 bits (409), Expect = 3e-39
 Identities = 115/420 (27%), Positives = 171/420 (40%), Gaps = 27/420 (6%)

Query: 161  KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
            K + C EC R F   + L  H  +H      +C +C+K F   S LK H     GEK + 
Sbjct: 656  KPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYE 715

Query: 221  CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
            C  C  +    +AL  H  ++H          Y C  C + F     L  H + HT    
Sbjct: 716  CNECEKTFAHNSALRAHQ-NIHTG-----EKLYECSECGKTFFQKTRLSTHRRIHTGEK- 768

Query: 281  AEPLPLRCFQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAHHKS 339
                P  C + G +++   +K+++   +  H G +  EC  + C   F    A+  H + 
Sbjct: 769  ----PYECSKCGKTFS---QKSYLSGHERIHTGEKPYEC--NVCGKTFVYKAALIVHQRI 819

Query: 340  HYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHA 396
            H     + C  C    S +     H++  H G +   C  C     +  A + H  ++H 
Sbjct: 820  HTGEKPYECNQCGKTFSQRTHLCAHQRI-HTGEKPYECNECGKTFADNSALRAH-HRIHT 877

Query: 397  HEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKD 456
             EK ++C +C    +    L  H+   +GEKP++C  C  T  + SY+S H   H+  K 
Sbjct: 878  GEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKP 937

Query: 457  YMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCE 515
            Y C  CG        LRVH R H G+  Y+CN C     +   LS+H+  H G K   C 
Sbjct: 938  YECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECN 997

Query: 516  VCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHC 575
             C  A  +   L+ H   + H G     Y C  C      K A+  H    HTR +   C
Sbjct: 998  ECGKAFAQNSTLRVHQ--RIHTGEKP--YECDECGKTFVRKAALRVHHTRMHTREKTLAC 1053



 Score =  160 bits (406), Expect = 7e-39
 Identities = 115/440 (26%), Positives = 170/440 (38%), Gaps = 26/440 (5%)

Query: 161  KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
            K + C EC R F   + L  H  +H  +   +C  C + FT  S L+ H     G K + 
Sbjct: 628  KPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYE 687

Query: 221  CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
            C  C  +    +AL  H   +H          Y C  C + F  + AL+ H   HT    
Sbjct: 688  CSDCEKTFAHNSALKIHQR-IHTG-----EKPYECNECEKTFAHNSALRAHQNIHTGEKL 741

Query: 281  AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
             E     C + G ++    R +   H +   G +  EC    C   F+    +  H + H
Sbjct: 742  YE-----CSECGKTFFQKTRLS--THRRIHTGEKPYECS--KCGKTFSQKSYLSGHERIH 792

Query: 341  YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                 + C  C      K     H++  H G +   C  C   TF+   +     ++H  
Sbjct: 793  TGEKPYECNVCGKTFVYKAALIVHQRI-HTGEKPYECNQCG-KTFSQRTHLCAHQRIHTG 850

Query: 398  EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
            EK ++C EC    A    L  H  +HTGEKP++C  C  T    S+L  H+ T S  K Y
Sbjct: 851  EKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPY 910

Query: 458  MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
             C+ECG     K Y+  H R H G+  Y+CN C         L  H+  H G KS  C  
Sbjct: 911  ECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECND 970

Query: 517  CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
            C     + +  + H+++     T    Y C+ C         +  H+   HT  + + C 
Sbjct: 971  CG----KTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRI-HTGEKPYECD 1025

Query: 577  LCDYRTFSNTTLLFHKRKAH 596
             C         L  H  + H
Sbjct: 1026 ECGKTFVRKAALRVHHTRMH 1045



 Score =  154 bits (390), Expect = 5e-37
 Identities = 123/472 (26%), Positives = 183/472 (38%), Gaps = 48/472 (10%)

Query: 155 GTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTS------------ 202
           GT   FK + C EC + F + ++L +HL +H  +       C + + S            
Sbjct: 432 GTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEM 491

Query: 203 ----------KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDT 252
                      S LK H    +GEK + C  C  +  + + L  H   +H          
Sbjct: 492 ELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQ-RIHTG-----EKP 545

Query: 253 YACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHG 312
           Y C  C + F     L  H + HT        P  C    C  +     A   H +   G
Sbjct: 546 YECVECEKTFSHKTHLSVHQRVHTGEK-----PYEC--NDCGKSFTYNSALRAHQRIHTG 598

Query: 313 VRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGS 369
            +  EC    C   FA   A+ AHH+ H     + C  C  + ++  + + H++  H G 
Sbjct: 599 EKPYEC--SDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRI-HTGE 655

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C  C  +     A + H  ++H   K ++C +C    AH   L  H  +HTGEKP+
Sbjct: 656 KPYECNECGRSFTYNSALRAH-QRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPY 714

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQ 489
           +C  C+ T    S L  H   H+  K Y C+ECG     K  L  H R H G+  Y+C++
Sbjct: 715 ECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSK 774

Query: 490 CSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHY 548
           C     +   LS H+  H G K   C VC      K  L  H   + H G     Y C+ 
Sbjct: 775 CGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVH--QRIHTGEKP--YECNQ 830

Query: 549 CSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           C      +  + +H+   HT  + + C  C      N+ L  H R   G  P
Sbjct: 831 CGKTFSQRTHLCAHQRI-HTGEKPYECNECGKTFADNSALRAHHRIHTGEKP 881



 Score =  118 bits (296), Expect = 4e-26
 Identities = 103/449 (22%), Positives = 173/449 (38%), Gaps = 33/449 (7%)

Query: 161 KTHMCPECKRC------FKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLREL 214
           K HM      C      F +++ L +         + +   C++ F+  S    H   + 
Sbjct: 289 KVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQA 348

Query: 215 GEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKS 274
           G+K      C  +  ++     H   +H +   + SD +    CR+ F     L +H + 
Sbjct: 349 GDKFGEHNECTDALYQKLDFTAHQR-IHTEDKFYLSDEHG--KCRKSFYRKAHLIQHQRP 405

Query: 275 HTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAME 334
           H+     +     C +  CS + P     I+H     G +  EC  + C   F     + 
Sbjct: 406 HSGEKTYQYE--ECAKSFCSSSHP-----IQHPGTYVGFKLYEC--NECGKAFCQNSNLS 456

Query: 335 AHHKSHYAFHCPHCDFACSNKHLFRKHKKQ--GHPGSEELRCTFCPFATFNPVAYQDHVG 392
            H + H        +  C N    R +K    GH  ++      C  + +   ++     
Sbjct: 457 KHLRIHTK------EKPCDNNGCGRSYKSPLIGHQKTDA-EMELCGGSEYGKTSHLKGHQ 509

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           ++   EK ++C EC    +    L  H  +HTGEKP++C  C+ T    ++LS H   H+
Sbjct: 510 RILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHT 569

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             K Y C +CG    +   LR H R H G+  Y+C+ C         L +H   H G K 
Sbjct: 570 GEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKP 629

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C  C  +      L+ H   + H G     Y C+ C     +  A+ +H+   HT  +
Sbjct: 630 YECNECGRSFAHISVLKAH--QRIHTGEKP--YECNECGRSFTYNSALRAHQRI-HTGRK 684

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + C+ C+     N+ L  H+R   G  P
Sbjct: 685 PYECSDCEKTFAHNSALKIHQRIHTGEKP 713



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 60/247 (24%), Positives = 92/247 (37%), Gaps = 34/247 (13%)

Query: 1442 HVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCH---LCPYACADPSRLKYH 1498
            H K   G +  +  +C  +   +   T H RIHT +K Y       C  +    + L  H
Sbjct: 343  HQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQH 402

Query: 1499 MRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPEC--EYC--TNRADALRVH 1554
             R H  E+ Y   EC       +    H   + G K Y+C EC   +C  +N +  LR+H
Sbjct: 403  QRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIH 462

Query: 1555 QETRHREARAFMCEQCGKAFKTRFL------------------LRTHLRKHSEA----KP 1592
             + +  +        CG+++K+  +                    +HL+ H       KP
Sbjct: 463  TKEKPCDNNG-----CGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKP 517

Query: 1593 YVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQ 1652
            Y C  C + F   + LR H   HT   P+ C  C      K  +  H R H  ++     
Sbjct: 518  YECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECN 577

Query: 1653 GVGKDPT 1659
              GK  T
Sbjct: 578  DCGKSFT 584



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 14/150 (9%)

Query: 156  TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
            T S  K + C EC + F +++++  H  +H  +   +C  C K F   S L+ H     G
Sbjct: 903  TRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTG 962

Query: 216  EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
            EK++ C  C  +  +++ L+ H   +H          Y C  C + F  +  L+ H + H
Sbjct: 963  EKSYECNDCGKTFSQKSHLSAHQ-RIHTG-----EKPYECNECGKAFAQNSTLRVHQRIH 1016

Query: 276  TAAAAAEPLPLRCFQEGCSYAAPDRKAFIK 305
            T        P  C + G ++    RKA ++
Sbjct: 1017 TGEK-----PYECDECGKTFV---RKAALR 1038



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 52/234 (22%), Positives = 91/234 (38%), Gaps = 33/234 (14%)

Query: 1462 KNRQKITWHSRIHTGEKPYHCHLCPY--ACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            KN  KIT  + + T  +     L  Y  +C   + ++Y+ ++H     Y C E G     
Sbjct: 250  KNFDKITLFNHMRTDTRGKCSDLNEYGTSCDKTTAVEYN-KVHMAMTHYECNERGINFSR 308

Query: 1520 VNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETR--------------------- 1558
             + L       TG   ++  +CE   +++ A  VHQ+T+                     
Sbjct: 309  KSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDF 368

Query: 1559 ------HREARAFMCEQ---CGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLR 1609
                  H E + ++ ++   C K+F  +  L  H R HS  K Y    C ++F  ++   
Sbjct: 369  TAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPI 428

Query: 1610 HHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTV 1663
             H  T+     + C  C     Q   + KH+R H  ++   N G G+   +P +
Sbjct: 429  QHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLI 482


>gi|156547246 zinc finger protein 160 [Homo sapiens]
          Length = 818

 Score =  236 bits (603), Expect = 1e-61
 Identities = 173/598 (28%), Positives = 243/598 (40%), Gaps = 53/598 (8%)

Query: 1068 VSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQK----GARFSCPTCPFSCQQERALRTHQ 1123
            VSPL    S+   + S +    +  ++L Q++K    G  + C  C  +  Q   L +H+
Sbjct: 217  VSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHR 276

Query: 1124 IRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCK 1181
                    SGE    CS C  T    + L +HQ           G +P+ +C +CG   +
Sbjct: 277  -----RIHSGEKPYKCSECGKTFTVRSNLTIHQVIH-------TGEKPY-KCHECGKVFR 323

Query: 1182 QSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNS 1241
             +  +  HRR+ H G KP++C  C  +      L  HQ  HTG     C+ C + F  NS
Sbjct: 324  HNSYLATHRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNS 382

Query: 1242 KLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETAL 1301
             L  H  R+H     + C  C  +  +R  +  H  + H G   + C++C   F   + L
Sbjct: 383  HLISH-WRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKPYKCNECGKVFRYNSYL 440

Query: 1302 KQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT--RKQHPRLECGAC 1359
             +H  RR              T E P  C+ CG      ++L  H          +C  C
Sbjct: 441  GRH--RR------------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNEC 486

Query: 1360 QEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEE------------ 1405
             + F     L  HRR       ++C  C  A   R  L  H      E            
Sbjct: 487  SKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSF 546

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T  +   S     +G+ P  C  C         L  H + H G + YKC DC  +  +R 
Sbjct: 547  TQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRS 606

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T+H  IHTGEKPY CH C       S L  H RIH  E+ Y C ECG      + L  
Sbjct: 607  SLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTT 666

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLR 1585
            H   HTG KPY+C +C     +   L  HQ T H   + + C +CGKAF  R  L TH  
Sbjct: 667  HKVIHTGEKPYKCNQCGKVFTQNSHLANHQRT-HTGEKPYRCNECGKAFSVRSSLTTHQA 725

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             H+  KPY CN C + F   A L +H   HT   P+ C  C    + +  +  H+  H
Sbjct: 726  IHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIH 783



 Score =  215 bits (548), Expect = 3e-55
 Identities = 145/475 (30%), Positives = 201/475 (42%), Gaps = 41/475 (8%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P  +C +CG    Q+  +  H R+ H G KP++C  C  + + R  L  HQ+ HTG 
Sbjct: 365  GEKP-FKCNECGKLFTQNSHLISHWRI-HTGEKPYKCNECGKAFSVRSSLAIHQTIHTGE 422

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C + F  NS L  HR RVH     + C  C  +  +  ++  H    H GT  
Sbjct: 423  KPYKCNECGKVFRYNSYLGRHR-RVHTGEKPYKCNECGKAFSMHSNLATH-QVIHTGTKP 480

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            F C++C   F+  + L  H  R H             T E P  C+ CG      +SL  
Sbjct: 481  FKCNECSKVFTQNSQLANHR-RIH-------------TGEKPYKCNECGKAFSVRSSLTT 526

Query: 1346 HT-----RKQHPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKH 1398
            H       K +  +ECG   ++F  +  L  HR        ++C  C     +   L +H
Sbjct: 527  HQAIHSGEKPYKCIECG---KSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARH 583

Query: 1399 YLEQHEE-----TSAAVAASDGDG-------DAGQPPLHCPFCDFTCRHQLVLDHHVKGH 1446
            +     E          A SD            G+ P  C  C    RH   L  H + H
Sbjct: 584  WRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH 643

Query: 1447 GGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEER 1506
             G + YKC +C  +      +T H  IHTGEKPY C+ C       S L  H R H  E+
Sbjct: 644  TGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703

Query: 1507 KYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFM 1566
             Y C ECG      + L  H   HTG KPY+C EC     +   L  H+   H   + + 
Sbjct: 704  PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRI-HTGEKPYR 762

Query: 1567 CEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPF 1621
            C +CGKAF+ R  L TH+  H+  K Y CN C + FR ++ L  H   HT   P+
Sbjct: 763  CTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817



 Score =  177 bits (449), Expect = 8e-44
 Identities = 122/444 (27%), Positives = 186/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F+  ++L  H  +H  +   +C  C K FT  S L +H     GEK + 
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYK 398

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R++L  H  ++H          Y C  C + FR +  L  H + HT    
Sbjct: 399 CNECGKAFSVRSSLAIHQ-TIHTG-----EKPYKCNECGKVFRYNSYLGRHRRVHTGEK- 451

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G +++     A   H     G +  +C  + C  +F     +  H + H
Sbjct: 452 ----PYKCNECGKAFSMHSNLA--THQVIHTGTKPFKC--NECSKVFTQNSQLANHRRIH 503

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +     H+   H G +  +C  C  +       + H G +H+ 
Sbjct: 504 TGEKPYKCNECGKAFSVRSSLTTHQAI-HSGEKPYKCIECGKSFTQKSHLRSHRG-IHSG 561

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC    A    L RH  +HTGEKP+KC  C     D S L+ H   H+  K Y
Sbjct: 562 EKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPY 621

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V +   YL  H R H G+  Y+CN+C         L++HK+ H G K   C  
Sbjct: 622 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQ 681

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     + +    H+A+     T    Y C+ C      + ++ +H+   HT  + + C 
Sbjct: 682 CG----KVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQ-AIHTGKKPYKCN 736

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C      N  L  H+R   G  P
Sbjct: 737 ECGKVFTQNAHLANHRRIHTGEKP 760



 Score =  163 bits (413), Expect = 1e-39
 Identities = 118/468 (25%), Positives = 177/468 (37%), Gaps = 46/468 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC + F + +HL+ H  +H  +   +C  C K F+ +S L  H     GEK + 
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C       + L RH   +H          Y C  C + F +   L  H   HT    
Sbjct: 427 CNECGKVFRYNSYLGRHRR-VHTG-----EKPYKCNECGKAFSMHSNLATHQVIHTGTK- 479

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  CS           H +   G +  +C  + C   F+   ++  H   H
Sbjct: 480 ----PFKCNE--CSKVFTQNSQLANHRRIHTGEKPYKC--NECGKAFSVRSSLTTHQAIH 531

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  + + K   R H+   H G +  +C  C    F   +      ++H  
Sbjct: 532 SGEKPYKCIECGKSFTQKSHLRSHRGI-HSGEKPYKCNECG-KVFAQTSQLARHWRVHTG 589

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  A + +  L  H  +HTGEKP+KC  C    R  SYL+ H   H+  K Y
Sbjct: 590 EKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY 649

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG        L  H   H G+  Y+CNQC     +   L++H+  H G K   C  
Sbjct: 650 KCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNE 709

Query: 517 CAFA------------------------CKRKYELQKHMASQHHPGTPAPLYPCHYCSYQ 552
           C  A                        C + +    H+A+     T    Y C  C   
Sbjct: 710 CGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKA 769

Query: 553 SRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            R + ++ +H    HT  + + C  C      ++ L  H R   G  P
Sbjct: 770 FRVRSSLTTH-MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKP 816



 Score =  162 bits (409), Expect = 3e-39
 Identities = 121/438 (27%), Positives = 176/438 (40%), Gaps = 30/438 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + ++L  H  +H  +   +C  C K FT +S L  H +   GEK + 
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C    V R+  N ++A+ H  I +     Y C  C + FR    L  H   HT    
Sbjct: 315 CHEC--GKVFRH--NSYLAT-HRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK- 367

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  C          I H +   G +  +C  + C   F+   ++  H   H
Sbjct: 368 ----PFKCNE--CGKLFTQNSHLISHWRIHTGEKPYKC--NECGKAFSVRSSLAIHQTIH 419

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQDHVGKMH 395
                + C  C           +H++  H G +  +C  C   F+  + +A    +   H
Sbjct: 420 TGEKPYKCNECGKVFRYNSYLGRHRRV-HTGEKPYKCNECGKAFSMHSNLATHQVI---H 475

Query: 396 AHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
              K  +C EC+        L  H  +HTGEKP+KC  C       S L+ H   HS  K
Sbjct: 476 TGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEK 535

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMC 514
            Y C ECG     K +LR H   H+G+  Y+CN+C     +  QL+ H   H G K   C
Sbjct: 536 PYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKC 595

Query: 515 EVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
             C  A   +  L  H A   H G     Y CH C    RH   + +H    HT  + + 
Sbjct: 596 NDCGRAFSDRSSLTFHQAI--HTGEKP--YKCHECGKVFRHNSYLATHRRI-HTGEKPYK 650

Query: 575 CALCDYRTFSNTTLLFHK 592
           C  C      ++ L  HK
Sbjct: 651 CNECGKAFSMHSNLTTHK 668



 Score =  110 bits (276), Expect = 9e-24
 Identities = 71/259 (27%), Positives = 105/259 (40%), Gaps = 8/259 (3%)

Query: 343 FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQ 402
           + C  C  A +       H++  H G +  +C+ C   TF   +       +H  EK ++
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRI-HSGEKPYKCSECG-KTFTVRSNLTIHQVIHTGEKPYK 314

Query: 403 CPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTEC 462
           C EC     H   L  H  +HTGEKP+KC  C    R  S L+ H L H+  K + C EC
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNEC 374

Query: 463 GYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFAC 521
           G +     +L  H R H G+  Y+CN+C         L+ H+  H G K   C  C    
Sbjct: 375 GKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG--- 431

Query: 522 KRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYR 581
            + +    ++       T    Y C+ C         + +H+   HT  + F C  C   
Sbjct: 432 -KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQ-VIHTGTKPFKCNECSKV 489

Query: 582 TFSNTTLLFHKRKAHGYVP 600
              N+ L  H+R   G  P
Sbjct: 490 FTQNSQLANHRRIHTGEKP 508



 Score =  103 bits (257), Expect = 1e-21
 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 7/205 (3%)

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           K ++  K ++C EC  A      L  H  +H+GEKP+KC  C  T    S L+ H + H+
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             K Y C ECG V +   YL  H R H G+  Y+CN+C         L++H+L H G K 
Sbjct: 309 GEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKP 368

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C  C     + +    H+ S     T    Y C+ C      + ++  H+   HT  +
Sbjct: 369 FKCNECG----KLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTI-HTGEK 423

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAH 596
            + C  C  + F   + L   R+ H
Sbjct: 424 PYKCNECG-KVFRYNSYLGRHRRVH 447



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 13/207 (6%)

Query: 395 HAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNT 454
           H  +K H+    +  T  ++        ++  KP+KC  C       S L+ H   HS  
Sbjct: 230 HRSKKYHELNHFSLLTQRRKA-------NSCGKPYKCNECGKAFTQNSNLTSHRRIHSGE 282

Query: 455 KDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLM 513
           K Y C+ECG     +  L +H   H G+  Y+C++C         L++H+  H G K   
Sbjct: 283 KPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYK 342

Query: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C  C  A +    L  H     H G     + C+ C         ++SH    HT  + +
Sbjct: 343 CNECGKAFRGHSNLTTHQLI--HTGEKP--FKCNECGKLFTQNSHLISHWRI-HTGEKPY 397

Query: 574 HCALCDYRTFSNTTLLFHKRKAHGYVP 600
            C  C       ++L  H+    G  P
Sbjct: 398 KCNECGKAFSVRSSLAIHQTIHTGEKP 424



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGL 881
           +  V+  GE + ++C  C  + R    L  H R  TG     +P  C ECG +F+    L
Sbjct: 302 IHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFRGHSNL 356

Query: 882 STHLL 886
           +TH L
Sbjct: 357 TTHQL 361



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           +   +  GE + ++C  C  + R    L  H R       +P  C ECG +F     L+T
Sbjct: 414 IHQTIHTGE-KPYKCNECGKVFRYNSYLGRHRRV--HTGEKPYKCNECGKAFSMHSNLAT 470

Query: 884 H 884
           H
Sbjct: 471 H 471



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  + R    L  H R  TG     +P  C ECG +F     L+TH
Sbjct: 619 KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFSMHSNLTTH 667



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + ++C  C  +  +   L  H RT      +P  C ECG +F  +  L+TH
Sbjct: 669 VIHTGEKPYKCNQCGKVFTQNSHLANHQRT--HTGEKPYRCNECGKAFSVRSSLTTH 723



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + F+C  C  +  +   L  H R  TG     +P  C ECG +F  +  L+TH
Sbjct: 473 VIHTGTKPFKCNECSKVFTQNSQLANHRRIHTG----EKPYKCNECGKAFSVRSSLTTH 527


>gi|38788302 zinc finger protein 160 [Homo sapiens]
          Length = 818

 Score =  236 bits (603), Expect = 1e-61
 Identities = 173/598 (28%), Positives = 243/598 (40%), Gaps = 53/598 (8%)

Query: 1068 VSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQK----GARFSCPTCPFSCQQERALRTHQ 1123
            VSPL    S+   + S +    +  ++L Q++K    G  + C  C  +  Q   L +H+
Sbjct: 217  VSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHR 276

Query: 1124 IRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCK 1181
                    SGE    CS C  T    + L +HQ           G +P+ +C +CG   +
Sbjct: 277  -----RIHSGEKPYKCSECGKTFTVRSNLTIHQVIH-------TGEKPY-KCHECGKVFR 323

Query: 1182 QSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNS 1241
             +  +  HRR+ H G KP++C  C  +      L  HQ  HTG     C+ C + F  NS
Sbjct: 324  HNSYLATHRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNS 382

Query: 1242 KLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETAL 1301
             L  H  R+H     + C  C  +  +R  +  H  + H G   + C++C   F   + L
Sbjct: 383  HLISH-WRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKPYKCNECGKVFRYNSYL 440

Query: 1302 KQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT--RKQHPRLECGAC 1359
             +H  RR              T E P  C+ CG      ++L  H          +C  C
Sbjct: 441  GRH--RR------------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNEC 486

Query: 1360 QEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEE------------ 1405
             + F     L  HRR       ++C  C  A   R  L  H      E            
Sbjct: 487  SKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSF 546

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T  +   S     +G+ P  C  C         L  H + H G + YKC DC  +  +R 
Sbjct: 547  TQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRS 606

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T+H  IHTGEKPY CH C       S L  H RIH  E+ Y C ECG      + L  
Sbjct: 607  SLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTT 666

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLR 1585
            H   HTG KPY+C +C     +   L  HQ T H   + + C +CGKAF  R  L TH  
Sbjct: 667  HKVIHTGEKPYKCNQCGKVFTQNSHLANHQRT-HTGEKPYRCNECGKAFSVRSSLTTHQA 725

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             H+  KPY CN C + F   A L +H   HT   P+ C  C    + +  +  H+  H
Sbjct: 726  IHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIH 783



 Score =  215 bits (548), Expect = 3e-55
 Identities = 145/475 (30%), Positives = 201/475 (42%), Gaps = 41/475 (8%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P  +C +CG    Q+  +  H R+ H G KP++C  C  + + R  L  HQ+ HTG 
Sbjct: 365  GEKP-FKCNECGKLFTQNSHLISHWRI-HTGEKPYKCNECGKAFSVRSSLAIHQTIHTGE 422

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C + F  NS L  HR RVH     + C  C  +  +  ++  H    H GT  
Sbjct: 423  KPYKCNECGKVFRYNSYLGRHR-RVHTGEKPYKCNECGKAFSMHSNLATH-QVIHTGTKP 480

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            F C++C   F+  + L  H  R H             T E P  C+ CG      +SL  
Sbjct: 481  FKCNECSKVFTQNSQLANHR-RIH-------------TGEKPYKCNECGKAFSVRSSLTT 526

Query: 1346 HT-----RKQHPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKH 1398
            H       K +  +ECG   ++F  +  L  HR        ++C  C     +   L +H
Sbjct: 527  HQAIHSGEKPYKCIECG---KSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARH 583

Query: 1399 YLEQHEE-----TSAAVAASDGDG-------DAGQPPLHCPFCDFTCRHQLVLDHHVKGH 1446
            +     E          A SD            G+ P  C  C    RH   L  H + H
Sbjct: 584  WRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH 643

Query: 1447 GGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEER 1506
             G + YKC +C  +      +T H  IHTGEKPY C+ C       S L  H R H  E+
Sbjct: 644  TGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703

Query: 1507 KYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFM 1566
             Y C ECG      + L  H   HTG KPY+C EC     +   L  H+   H   + + 
Sbjct: 704  PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRI-HTGEKPYR 762

Query: 1567 CEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPF 1621
            C +CGKAF+ R  L TH+  H+  K Y CN C + FR ++ L  H   HT   P+
Sbjct: 763  CTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817



 Score =  177 bits (449), Expect = 8e-44
 Identities = 122/444 (27%), Positives = 186/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F+  ++L  H  +H  +   +C  C K FT  S L +H     GEK + 
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYK 398

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R++L  H  ++H          Y C  C + FR +  L  H + HT    
Sbjct: 399 CNECGKAFSVRSSLAIHQ-TIHTG-----EKPYKCNECGKVFRYNSYLGRHRRVHTGEK- 451

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G +++     A   H     G +  +C  + C  +F     +  H + H
Sbjct: 452 ----PYKCNECGKAFSMHSNLA--THQVIHTGTKPFKC--NECSKVFTQNSQLANHRRIH 503

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +     H+   H G +  +C  C  +       + H G +H+ 
Sbjct: 504 TGEKPYKCNECGKAFSVRSSLTTHQAI-HSGEKPYKCIECGKSFTQKSHLRSHRG-IHSG 561

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC    A    L RH  +HTGEKP+KC  C     D S L+ H   H+  K Y
Sbjct: 562 EKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPY 621

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V +   YL  H R H G+  Y+CN+C         L++HK+ H G K   C  
Sbjct: 622 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQ 681

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     + +    H+A+     T    Y C+ C      + ++ +H+   HT  + + C 
Sbjct: 682 CG----KVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQ-AIHTGKKPYKCN 736

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C      N  L  H+R   G  P
Sbjct: 737 ECGKVFTQNAHLANHRRIHTGEKP 760



 Score =  163 bits (413), Expect = 1e-39
 Identities = 118/468 (25%), Positives = 177/468 (37%), Gaps = 46/468 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC + F + +HL+ H  +H  +   +C  C K F+ +S L  H     GEK + 
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C       + L RH   +H          Y C  C + F +   L  H   HT    
Sbjct: 427 CNECGKVFRYNSYLGRHRR-VHTG-----EKPYKCNECGKAFSMHSNLATHQVIHTGTK- 479

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  CS           H +   G +  +C  + C   F+   ++  H   H
Sbjct: 480 ----PFKCNE--CSKVFTQNSQLANHRRIHTGEKPYKC--NECGKAFSVRSSLTTHQAIH 531

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  + + K   R H+   H G +  +C  C    F   +      ++H  
Sbjct: 532 SGEKPYKCIECGKSFTQKSHLRSHRGI-HSGEKPYKCNECG-KVFAQTSQLARHWRVHTG 589

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  A + +  L  H  +HTGEKP+KC  C    R  SYL+ H   H+  K Y
Sbjct: 590 EKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY 649

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG        L  H   H G+  Y+CNQC     +   L++H+  H G K   C  
Sbjct: 650 KCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNE 709

Query: 517 CAFA------------------------CKRKYELQKHMASQHHPGTPAPLYPCHYCSYQ 552
           C  A                        C + +    H+A+     T    Y C  C   
Sbjct: 710 CGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKA 769

Query: 553 SRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            R + ++ +H    HT  + + C  C      ++ L  H R   G  P
Sbjct: 770 FRVRSSLTTH-MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKP 816



 Score =  162 bits (409), Expect = 3e-39
 Identities = 121/438 (27%), Positives = 176/438 (40%), Gaps = 30/438 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + ++L  H  +H  +   +C  C K FT +S L  H +   GEK + 
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C    V R+  N ++A+ H  I +     Y C  C + FR    L  H   HT    
Sbjct: 315 CHEC--GKVFRH--NSYLAT-HRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK- 367

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  C          I H +   G +  +C  + C   F+   ++  H   H
Sbjct: 368 ----PFKCNE--CGKLFTQNSHLISHWRIHTGEKPYKC--NECGKAFSVRSSLAIHQTIH 419

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQDHVGKMH 395
                + C  C           +H++  H G +  +C  C   F+  + +A    +   H
Sbjct: 420 TGEKPYKCNECGKVFRYNSYLGRHRRV-HTGEKPYKCNECGKAFSMHSNLATHQVI---H 475

Query: 396 AHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
              K  +C EC+        L  H  +HTGEKP+KC  C       S L+ H   HS  K
Sbjct: 476 TGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEK 535

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMC 514
            Y C ECG     K +LR H   H+G+  Y+CN+C     +  QL+ H   H G K   C
Sbjct: 536 PYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKC 595

Query: 515 EVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
             C  A   +  L  H A   H G     Y CH C    RH   + +H    HT  + + 
Sbjct: 596 NDCGRAFSDRSSLTFHQAI--HTGEKP--YKCHECGKVFRHNSYLATHRRI-HTGEKPYK 650

Query: 575 CALCDYRTFSNTTLLFHK 592
           C  C      ++ L  HK
Sbjct: 651 CNECGKAFSMHSNLTTHK 668



 Score =  110 bits (276), Expect = 9e-24
 Identities = 71/259 (27%), Positives = 105/259 (40%), Gaps = 8/259 (3%)

Query: 343 FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQ 402
           + C  C  A +       H++  H G +  +C+ C   TF   +       +H  EK ++
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRI-HSGEKPYKCSECG-KTFTVRSNLTIHQVIHTGEKPYK 314

Query: 403 CPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTEC 462
           C EC     H   L  H  +HTGEKP+KC  C    R  S L+ H L H+  K + C EC
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNEC 374

Query: 463 GYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFAC 521
           G +     +L  H R H G+  Y+CN+C         L+ H+  H G K   C  C    
Sbjct: 375 GKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG--- 431

Query: 522 KRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYR 581
            + +    ++       T    Y C+ C         + +H+   HT  + F C  C   
Sbjct: 432 -KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQ-VIHTGTKPFKCNECSKV 489

Query: 582 TFSNTTLLFHKRKAHGYVP 600
              N+ L  H+R   G  P
Sbjct: 490 FTQNSQLANHRRIHTGEKP 508



 Score =  103 bits (257), Expect = 1e-21
 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 7/205 (3%)

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           K ++  K ++C EC  A      L  H  +H+GEKP+KC  C  T    S L+ H + H+
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             K Y C ECG V +   YL  H R H G+  Y+CN+C         L++H+L H G K 
Sbjct: 309 GEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKP 368

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C  C     + +    H+ S     T    Y C+ C      + ++  H+   HT  +
Sbjct: 369 FKCNECG----KLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTI-HTGEK 423

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAH 596
            + C  C  + F   + L   R+ H
Sbjct: 424 PYKCNECG-KVFRYNSYLGRHRRVH 447



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 13/207 (6%)

Query: 395 HAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNT 454
           H  +K H+    +  T  ++        ++  KP+KC  C       S L+ H   HS  
Sbjct: 230 HRSKKYHELNHFSLLTQRRKA-------NSCGKPYKCNECGKAFTQNSNLTSHRRIHSGE 282

Query: 455 KDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLM 513
           K Y C+ECG     +  L +H   H G+  Y+C++C         L++H+  H G K   
Sbjct: 283 KPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYK 342

Query: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C  C  A +    L  H     H G     + C+ C         ++SH    HT  + +
Sbjct: 343 CNECGKAFRGHSNLTTHQLI--HTGEKP--FKCNECGKLFTQNSHLISHWRI-HTGEKPY 397

Query: 574 HCALCDYRTFSNTTLLFHKRKAHGYVP 600
            C  C       ++L  H+    G  P
Sbjct: 398 KCNECGKAFSVRSSLAIHQTIHTGEKP 424



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGL 881
           +  V+  GE + ++C  C  + R    L  H R  TG     +P  C ECG +F+    L
Sbjct: 302 IHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFRGHSNL 356

Query: 882 STHLL 886
           +TH L
Sbjct: 357 TTHQL 361



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           +   +  GE + ++C  C  + R    L  H R       +P  C ECG +F     L+T
Sbjct: 414 IHQTIHTGE-KPYKCNECGKVFRYNSYLGRHRRV--HTGEKPYKCNECGKAFSMHSNLAT 470

Query: 884 H 884
           H
Sbjct: 471 H 471



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  + R    L  H R  TG     +P  C ECG +F     L+TH
Sbjct: 619 KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFSMHSNLTTH 667



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + ++C  C  +  +   L  H RT      +P  C ECG +F  +  L+TH
Sbjct: 669 VIHTGEKPYKCNQCGKVFTQNSHLANHQRT--HTGEKPYRCNECGKAFSVRSSLTTH 723



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + F+C  C  +  +   L  H R  TG     +P  C ECG +F  +  L+TH
Sbjct: 473 VIHTGTKPFKCNECSKVFTQNSQLANHRRIHTG----EKPYKCNECGKAFSVRSSLTTH 527


>gi|38788288 zinc finger protein 160 [Homo sapiens]
          Length = 818

 Score =  236 bits (603), Expect = 1e-61
 Identities = 173/598 (28%), Positives = 243/598 (40%), Gaps = 53/598 (8%)

Query: 1068 VSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQK----GARFSCPTCPFSCQQERALRTHQ 1123
            VSPL    S+   + S +    +  ++L Q++K    G  + C  C  +  Q   L +H+
Sbjct: 217  VSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHR 276

Query: 1124 IRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCK 1181
                    SGE    CS C  T    + L +HQ           G +P+ +C +CG   +
Sbjct: 277  -----RIHSGEKPYKCSECGKTFTVRSNLTIHQVIH-------TGEKPY-KCHECGKVFR 323

Query: 1182 QSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNS 1241
             +  +  HRR+ H G KP++C  C  +      L  HQ  HTG     C+ C + F  NS
Sbjct: 324  HNSYLATHRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNS 382

Query: 1242 KLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETAL 1301
             L  H  R+H     + C  C  +  +R  +  H  + H G   + C++C   F   + L
Sbjct: 383  HLISH-WRIHTGEKPYKCNECGKAFSVRSSLAIH-QTIHTGEKPYKCNECGKVFRYNSYL 440

Query: 1302 KQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT--RKQHPRLECGAC 1359
             +H  RR              T E P  C+ CG      ++L  H          +C  C
Sbjct: 441  GRH--RR------------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNEC 486

Query: 1360 QEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEE------------ 1405
             + F     L  HRR       ++C  C  A   R  L  H      E            
Sbjct: 487  SKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSF 546

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T  +   S     +G+ P  C  C         L  H + H G + YKC DC  +  +R 
Sbjct: 547  TQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRS 606

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T+H  IHTGEKPY CH C       S L  H RIH  E+ Y C ECG      + L  
Sbjct: 607  SLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTT 666

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLR 1585
            H   HTG KPY+C +C     +   L  HQ T H   + + C +CGKAF  R  L TH  
Sbjct: 667  HKVIHTGEKPYKCNQCGKVFTQNSHLANHQRT-HTGEKPYRCNECGKAFSVRSSLTTHQA 725

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             H+  KPY CN C + F   A L +H   HT   P+ C  C    + +  +  H+  H
Sbjct: 726  IHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIH 783



 Score =  215 bits (548), Expect = 3e-55
 Identities = 145/475 (30%), Positives = 201/475 (42%), Gaps = 41/475 (8%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P  +C +CG    Q+  +  H R+ H G KP++C  C  + + R  L  HQ+ HTG 
Sbjct: 365  GEKP-FKCNECGKLFTQNSHLISHWRI-HTGEKPYKCNECGKAFSVRSSLAIHQTIHTGE 422

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C + F  NS L  HR RVH     + C  C  +  +  ++  H    H GT  
Sbjct: 423  KPYKCNECGKVFRYNSYLGRHR-RVHTGEKPYKCNECGKAFSMHSNLATH-QVIHTGTKP 480

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            F C++C   F+  + L  H  R H             T E P  C+ CG      +SL  
Sbjct: 481  FKCNECSKVFTQNSQLANHR-RIH-------------TGEKPYKCNECGKAFSVRSSLTT 526

Query: 1346 HT-----RKQHPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKH 1398
            H       K +  +ECG   ++F  +  L  HR        ++C  C     +   L +H
Sbjct: 527  HQAIHSGEKPYKCIECG---KSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARH 583

Query: 1399 YLEQHEE-----TSAAVAASDGDG-------DAGQPPLHCPFCDFTCRHQLVLDHHVKGH 1446
            +     E          A SD            G+ P  C  C    RH   L  H + H
Sbjct: 584  WRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH 643

Query: 1447 GGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEER 1506
             G + YKC +C  +      +T H  IHTGEKPY C+ C       S L  H R H  E+
Sbjct: 644  TGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEK 703

Query: 1507 KYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFM 1566
             Y C ECG      + L  H   HTG KPY+C EC     +   L  H+   H   + + 
Sbjct: 704  PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRI-HTGEKPYR 762

Query: 1567 CEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPF 1621
            C +CGKAF+ R  L TH+  H+  K Y CN C + FR ++ L  H   HT   P+
Sbjct: 763  CTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817



 Score =  177 bits (449), Expect = 8e-44
 Identities = 122/444 (27%), Positives = 186/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F+  ++L  H  +H  +   +C  C K FT  S L +H     GEK + 
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYK 398

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R++L  H  ++H          Y C  C + FR +  L  H + HT    
Sbjct: 399 CNECGKAFSVRSSLAIHQ-TIHTG-----EKPYKCNECGKVFRYNSYLGRHRRVHTGEK- 451

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G +++     A   H     G +  +C  + C  +F     +  H + H
Sbjct: 452 ----PYKCNECGKAFSMHSNLA--THQVIHTGTKPFKC--NECSKVFTQNSQLANHRRIH 503

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +     H+   H G +  +C  C  +       + H G +H+ 
Sbjct: 504 TGEKPYKCNECGKAFSVRSSLTTHQAI-HSGEKPYKCIECGKSFTQKSHLRSHRG-IHSG 561

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC    A    L RH  +HTGEKP+KC  C     D S L+ H   H+  K Y
Sbjct: 562 EKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPY 621

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V +   YL  H R H G+  Y+CN+C         L++HK+ H G K   C  
Sbjct: 622 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQ 681

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     + +    H+A+     T    Y C+ C      + ++ +H+   HT  + + C 
Sbjct: 682 CG----KVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQ-AIHTGKKPYKCN 736

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C      N  L  H+R   G  P
Sbjct: 737 ECGKVFTQNAHLANHRRIHTGEKP 760



 Score =  163 bits (413), Expect = 1e-39
 Identities = 118/468 (25%), Positives = 177/468 (37%), Gaps = 46/468 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC + F + +HL+ H  +H  +   +C  C K F+ +S L  H     GEK + 
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C       + L RH   +H          Y C  C + F +   L  H   HT    
Sbjct: 427 CNECGKVFRYNSYLGRHRR-VHTG-----EKPYKCNECGKAFSMHSNLATHQVIHTGTK- 479

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  CS           H +   G +  +C  + C   F+   ++  H   H
Sbjct: 480 ----PFKCNE--CSKVFTQNSQLANHRRIHTGEKPYKC--NECGKAFSVRSSLTTHQAIH 531

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  + + K   R H+   H G +  +C  C    F   +      ++H  
Sbjct: 532 SGEKPYKCIECGKSFTQKSHLRSHRGI-HSGEKPYKCNECG-KVFAQTSQLARHWRVHTG 589

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  A + +  L  H  +HTGEKP+KC  C    R  SYL+ H   H+  K Y
Sbjct: 590 EKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY 649

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG        L  H   H G+  Y+CNQC     +   L++H+  H G K   C  
Sbjct: 650 KCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNE 709

Query: 517 CAFA------------------------CKRKYELQKHMASQHHPGTPAPLYPCHYCSYQ 552
           C  A                        C + +    H+A+     T    Y C  C   
Sbjct: 710 CGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKA 769

Query: 553 SRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            R + ++ +H    HT  + + C  C      ++ L  H R   G  P
Sbjct: 770 FRVRSSLTTH-MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKP 816



 Score =  162 bits (409), Expect = 3e-39
 Identities = 121/438 (27%), Positives = 176/438 (40%), Gaps = 30/438 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + ++L  H  +H  +   +C  C K FT +S L  H +   GEK + 
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C    V R+  N ++A+ H  I +     Y C  C + FR    L  H   HT    
Sbjct: 315 CHEC--GKVFRH--NSYLAT-HRRI-HTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK- 367

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  C          I H +   G +  +C  + C   F+   ++  H   H
Sbjct: 368 ----PFKCNE--CGKLFTQNSHLISHWRIHTGEKPYKC--NECGKAFSVRSSLAIHQTIH 419

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQDHVGKMH 395
                + C  C           +H++  H G +  +C  C   F+  + +A    +   H
Sbjct: 420 TGEKPYKCNECGKVFRYNSYLGRHRRV-HTGEKPYKCNECGKAFSMHSNLATHQVI---H 475

Query: 396 AHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
              K  +C EC+        L  H  +HTGEKP+KC  C       S L+ H   HS  K
Sbjct: 476 TGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEK 535

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMC 514
            Y C ECG     K +LR H   H+G+  Y+CN+C     +  QL+ H   H G K   C
Sbjct: 536 PYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKC 595

Query: 515 EVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
             C  A   +  L  H A   H G     Y CH C    RH   + +H    HT  + + 
Sbjct: 596 NDCGRAFSDRSSLTFHQAI--HTGEKP--YKCHECGKVFRHNSYLATHRRI-HTGEKPYK 650

Query: 575 CALCDYRTFSNTTLLFHK 592
           C  C      ++ L  HK
Sbjct: 651 CNECGKAFSMHSNLTTHK 668



 Score =  110 bits (276), Expect = 9e-24
 Identities = 71/259 (27%), Positives = 105/259 (40%), Gaps = 8/259 (3%)

Query: 343 FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQ 402
           + C  C  A +       H++  H G +  +C+ C   TF   +       +H  EK ++
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRI-HSGEKPYKCSECG-KTFTVRSNLTIHQVIHTGEKPYK 314

Query: 403 CPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTEC 462
           C EC     H   L  H  +HTGEKP+KC  C    R  S L+ H L H+  K + C EC
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNEC 374

Query: 463 GYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFAC 521
           G +     +L  H R H G+  Y+CN+C         L+ H+  H G K   C  C    
Sbjct: 375 GKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG--- 431

Query: 522 KRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYR 581
            + +    ++       T    Y C+ C         + +H+   HT  + F C  C   
Sbjct: 432 -KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQ-VIHTGTKPFKCNECSKV 489

Query: 582 TFSNTTLLFHKRKAHGYVP 600
              N+ L  H+R   G  P
Sbjct: 490 FTQNSQLANHRRIHTGEKP 508



 Score =  103 bits (257), Expect = 1e-21
 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 7/205 (3%)

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           K ++  K ++C EC  A      L  H  +H+GEKP+KC  C  T    S L+ H + H+
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             K Y C ECG V +   YL  H R H G+  Y+CN+C         L++H+L H G K 
Sbjct: 309 GEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKP 368

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C  C     + +    H+ S     T    Y C+ C      + ++  H+   HT  +
Sbjct: 369 FKCNECG----KLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTI-HTGEK 423

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAH 596
            + C  C  + F   + L   R+ H
Sbjct: 424 PYKCNECG-KVFRYNSYLGRHRRVH 447



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 13/207 (6%)

Query: 395 HAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNT 454
           H  +K H+    +  T  ++        ++  KP+KC  C       S L+ H   HS  
Sbjct: 230 HRSKKYHELNHFSLLTQRRKA-------NSCGKPYKCNECGKAFTQNSNLTSHRRIHSGE 282

Query: 455 KDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLM 513
           K Y C+ECG     +  L +H   H G+  Y+C++C         L++H+  H G K   
Sbjct: 283 KPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYK 342

Query: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C  C  A +    L  H     H G     + C+ C         ++SH    HT  + +
Sbjct: 343 CNECGKAFRGHSNLTTHQLI--HTGEKP--FKCNECGKLFTQNSHLISHWRI-HTGEKPY 397

Query: 574 HCALCDYRTFSNTTLLFHKRKAHGYVP 600
            C  C       ++L  H+    G  P
Sbjct: 398 KCNECGKAFSVRSSLAIHQTIHTGEKP 424



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGL 881
           +  V+  GE + ++C  C  + R    L  H R  TG     +P  C ECG +F+    L
Sbjct: 302 IHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFRGHSNL 356

Query: 882 STHLL 886
           +TH L
Sbjct: 357 TTHQL 361



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           +   +  GE + ++C  C  + R    L  H R       +P  C ECG +F     L+T
Sbjct: 414 IHQTIHTGE-KPYKCNECGKVFRYNSYLGRHRRV--HTGEKPYKCNECGKAFSMHSNLAT 470

Query: 884 H 884
           H
Sbjct: 471 H 471



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  + R    L  H R  TG     +P  C ECG +F     L+TH
Sbjct: 619 KPYKCHECGKVFRHNSYLATHRRIHTG----EKPYKCNECGKAFSMHSNLTTH 667



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + ++C  C  +  +   L  H RT      +P  C ECG +F  +  L+TH
Sbjct: 669 VIHTGEKPYKCNQCGKVFTQNSHLANHQRT--HTGEKPYRCNECGKAFSVRSSLTTH 723



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           VI    + F+C  C  +  +   L  H R  TG     +P  C ECG +F  +  L+TH
Sbjct: 473 VIHTGTKPFKCNECSKVFTQNSQLANHRRIHTG----EKPYKCNECGKAFSVRSSLTTH 527


>gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]
          Length = 810

 Score =  231 bits (589), Expect = 4e-60
 Identities = 145/480 (30%), Positives = 204/480 (42%), Gaps = 42/480 (8%)

Query: 1170 HLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIP 1229
            H +C +CG    +   + +H+R+ H G KP QC  C+ +   +  L  HQ  HTG     
Sbjct: 327  HFECNECGKAFWEKSHLTRHQRV-HTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFE 385

Query: 1230 CSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACS 1289
            C+ C + F   S L LH+ R H     + C  C  +   + D+T+H  + H G   + C 
Sbjct: 386  CNECGKAFSHKSALTLHQ-RTHTGEKPYQCNACGKTFCQKSDLTKHQRT-HTGLKPYECY 443

Query: 1290 QCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRK 1349
            +C   F   + LK H  R H             T E P  C  CG      ++L  H R 
Sbjct: 444  ECGKSFRVTSHLKVHQ-RTH-------------TGEKPFECLECGKSFSEKSNLTQHQRI 489

Query: 1350 Q--HPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKHYLEQHEE 1405
                   EC AC + F  +  L  H+        + C  C      +   +K  L  H+ 
Sbjct: 490  HIGDKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECG-----KTFCLKSDLTVHQR 544

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T             GQ P  CP C     H+  L  H + H G + Y+C +C     N+ 
Sbjct: 545  THT-----------GQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKS 593

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T H+R HTGEKPY C+ C  A    S+L  H RIH  E+ Y C ECG      + L  
Sbjct: 594  YLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIV 653

Query: 1526 HMTKHTGLKPYQCPEC--EYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTH 1583
            H   HT  KPY+C EC   +C        +  E +H   + + C +CGK F+ +  L  H
Sbjct: 654  HQRTHTQEKPYKCNECGKSFCVKSG---LIFHERKHTGEKPYECNECGKFFRHKSSLTVH 710

Query: 1584 LRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             R H+  K   CN C + F   + L  H  +HT   P+ C  C     QK  ++ H RRH
Sbjct: 711  HRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRH 770



 Score =  192 bits (487), Expect = 3e-48
 Identities = 155/554 (27%), Positives = 222/554 (40%), Gaps = 54/554 (9%)

Query: 1111 FSCQQERALRTHQIRGCPLEESGELHCSLCPF--TAPAATALRLHQKRRHPTAAPARGPR 1168
            +S  QE  L          E + E +C    F  T   +++L  HQ       +P+R   
Sbjct: 220  YSICQETLLEKAVFNTQKRENAEENNCDYNEFGRTLCDSSSLLFHQ------ISPSRDN- 272

Query: 1169 PHLQCGDCG-FTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGR 1227
             H +  DC  F C +S   + H       +K + C     +  R+  L   Q    G   
Sbjct: 273  -HYEFSDCEKFLCVKSTLSKPHG----VSMKHYDCGESGNNFRRKLCLSHLQKGDKGEKH 327

Query: 1228 IPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFA 1287
              C+ C + F   S L  H+ RVH       C  C+ + + + ++T+H  S H G   F 
Sbjct: 328  FECNECGKAFWEKSHLTRHQ-RVHTGQKPFQCNECEKAFWDKSNLTKHQRS-HTGEKPFE 385

Query: 1288 CSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT 1347
            C++C   FS ++AL  H  R H             T E P  C+ CG      + L  H 
Sbjct: 386  CNECGKAFSHKSALTLHQ-RTH-------------TGEKPYQCNACGKTFCQKSDLTKHQ 431

Query: 1348 RKQHPRL---ECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQ 1402
            R  H  L   EC  C ++F     L  H+R         C  C  +  E+  L +H    
Sbjct: 432  RT-HTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH 490

Query: 1403 HEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTK 1462
                             G     C  C  T  H+ +L  H   H G + Y+C +C  +  
Sbjct: 491  ----------------IGDKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFC 534

Query: 1463 NRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQ 1522
             +  +T H R HTG+KP+ C  C    +  S L  H R H  E+ Y C ECG      + 
Sbjct: 535  LKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSY 594

Query: 1523 LKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRT 1582
            L  H   HTG KPY+C EC     +   L  HQ   H   + + C +CGKAF  +  L  
Sbjct: 595  LTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRI-HIGEKPYKCNECGKAFCHKSALIV 653

Query: 1583 HLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRR 1642
            H R H++ KPY CN C ++F   +GL  H   HT   P+ C  C    + K  +  H R 
Sbjct: 654  HQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRA 713

Query: 1643 HHPDQADPNQGVGK 1656
            H  +++      GK
Sbjct: 714  HTGEKSCQCNECGK 727



 Score =  179 bits (454), Expect = 2e-44
 Identities = 122/433 (28%), Positives = 179/433 (41%), Gaps = 49/433 (11%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC++ F  +++L +H   H  +   +C  C K F+ KS L  H     GEK + 
Sbjct: 354 KPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQ 413

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L +H  + H  +       Y C  C + FR++  LK H ++HT    
Sbjct: 414 CNACGKTFCQKSDLTKHQRT-HTGLK-----PYECYECGKSFRVTSHLKVHQRTHTGEK- 466

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC--------------RH------ 320
               P  C + G S++  ++    +H +   G ++ EC              RH      
Sbjct: 467 ----PFECLECGKSFS--EKSNLTQHQRIHIGDKSYECNACGKTFYHKSLLTRHQIIHTG 520

Query: 321 ------HSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEE 371
                 + C   F     +  H ++H     F CP C    S+K    +H +  H G + 
Sbjct: 521 WKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRT-HTGEKP 579

Query: 372 LRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKC 431
             C  C    +N  +Y     + H  EK ++C EC  A   K  L +H  +H GEKP+KC
Sbjct: 580 YECHECGKIFYNK-SYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKC 638

Query: 432 ELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCS 491
             C       S L  H  TH+  K Y C ECG     K  L  H RKH G+  Y+CN+C 
Sbjct: 639 NECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECG 698

Query: 492 YRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCS 550
                   L+ H   H G KS  C  C     RK EL +H  S  H G     Y C+ C 
Sbjct: 699 KFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRS--HTGEKP--YECNTCR 754

Query: 551 YQSRHKQAVLSHE 563
                K  ++ H+
Sbjct: 755 KTFSQKSNLIVHQ 767



 Score =  178 bits (452), Expect = 3e-44
 Identities = 126/441 (28%), Positives = 183/441 (41%), Gaps = 28/441 (6%)

Query: 165 CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLC 224
           C EC + F +++HL  H  +H      QC  C+K F  KS L  H     GEK   C  C
Sbjct: 330 CNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNEC 389

Query: 225 HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPL 284
             +   ++AL  H        ++     Y C  C + F     L +H ++HT        
Sbjct: 390 GKAFSHKSALTLHQR------THTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLK----- 438

Query: 285 PLRCFQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAHHKSHY-- 341
           P  C++ G S+      + +K  + TH G +  EC    C   F+    +  H + H   
Sbjct: 439 PYECYECGKSFRV---TSHLKVHQRTHTGEKPFECL--ECGKSFSEKSNLTQHQRIHIGD 493

Query: 342 -AFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
            ++ C  C     +K L  +H+   H G +   C  C   TF   +      + H  +K 
Sbjct: 494 KSYECNACGKTFYHKSLLTRHQII-HTGWKPYECYECG-KTFCLKSDLTVHQRTHTGQKP 551

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
             CPEC    +HK  L +H   HTGEKP++C  C     + SYL+KH  TH+  K Y C 
Sbjct: 552 FACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECN 611

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYR-CHRADQLSSHKLRHQGKSLMCEVCAF 519
           ECG     K  L  H R H G+  Y+CN+C    CH++  +   +   Q K   C  C  
Sbjct: 612 ECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGK 671

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           +   K  L  H   + H G     Y C+ C    RHK ++  H    HT  +   C  C 
Sbjct: 672 SFCVKSGLIFH--ERKHTGEKP--YECNECGKFFRHKSSLTVHHRA-HTGEKSCQCNECG 726

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
              +  + L  H+R   G  P
Sbjct: 727 KIFYRKSELAQHQRSHTGEKP 747



 Score =  163 bits (412), Expect = 2e-39
 Identities = 105/364 (28%), Positives = 157/364 (43%), Gaps = 20/364 (5%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T +  K + C EC + F+  +HL  H   H  +   +C  C K F+ KS L  H    +G
Sbjct: 433 THTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIG 492

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           +K++ C  C  +   ++ L RH       I +     Y C  C + F L   L  H ++H
Sbjct: 493 DKSYECNACGKTFYHKSLLTRHQ------IIHTGWKPYECYECGKTFCLKSDLTVHQRTH 546

Query: 276 TAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEA 335
           T        P  C +  C      +    +H +   G +  EC  H C  +F     +  
Sbjct: 547 TGQK-----PFACPE--CGKFFSHKSTLSQHYRTHTGEKPYEC--HECGKIFYNKSYLTK 597

Query: 336 HHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVG 392
           H+++H     + C  C  A   K    +H++  H G +  +C  C  A  +  A   H  
Sbjct: 598 HNRTHTGEKPYECNECGKAFYQKSQLTQHQRI-HIGEKPYKCNECGKAFCHKSALIVHQ- 655

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           + H  EK ++C EC  +   K  LI H   HTGEKP++C  C    R  S L+ H   H+
Sbjct: 656 RTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRAHT 715

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSL 512
             K   C ECG +   K  L  H R H G+  Y+CN C     +   L  H+ RH G++L
Sbjct: 716 GEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRHIGENL 775

Query: 513 MCEV 516
           M E+
Sbjct: 776 MNEM 779



 Score =  148 bits (374), Expect = 4e-35
 Identities = 117/435 (26%), Positives = 176/435 (40%), Gaps = 52/435 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +   + AL  HQ        +GE    C+ C  T    + L  HQ+      
Sbjct: 384  FECNECGKAFSHKSALTLHQ-----RTHTGEKPYQCNACGKTFCQKSDLTKHQRTH---- 434

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG + + +  ++ H+R  H G KP +C  C  S + +  L  HQ  
Sbjct: 435  ---TGLKPY-ECYECGKSFRVTSHLKVHQRT-HTGEKPFECLECGKSFSEKSNLTQHQRI 489

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            H G     C++C +TF   S L  H++ +H     + C  C  +  L+ D+T H  + H 
Sbjct: 490  HIGDKSYECNACGKTFYHKSLLTRHQI-IHTGWKPYECYECGKTFCLKSDLTVHQRT-HT 547

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   FAC +C   FS ++ L QH  R H             T E P  C  CG +  + +
Sbjct: 548  GQKPFACPECGKFFSHKSTLSQH-YRTH-------------TGEKPYECHECGKIFYNKS 593

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C +AF  +  L +H+R       ++C  C  A   +  L+ 
Sbjct: 594  YLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIV 653

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H     +E                 P  C  C  +   +  L  H + H G + Y+C +C
Sbjct: 654  HQRTHTQEK----------------PYKCNECGKSFCVKSGLIFHERKHTGEKPYECNEC 697

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
                +++  +T H R HTGEK   C+ C       S L  H R H  E+ Y C  C    
Sbjct: 698  GKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTF 757

Query: 1518 KWVNQLKYHMTKHTG 1532
               + L  H  +H G
Sbjct: 758  SQKSNLIVHQRRHIG 772



 Score =  124 bits (311), Expect = 8e-28
 Identities = 114/451 (25%), Positives = 167/451 (37%), Gaps = 53/451 (11%)

Query: 192 QCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVE-----------------RNAL 234
           QC +C   F + S+L    +  LG+K+     C    +                  RN L
Sbjct: 140 QCDSCGMSFNTVSELVISKINYLGKKSDEFNACGKLLLNIKHDETHTQEKNEVLKNRNTL 199

Query: 235 NRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAA-----------AAAEP 283
           + H  ++  +        +   +C+E   L +A+    K   A               + 
Sbjct: 200 SHHEETLQHEKIQTLEHNFEYSICQETL-LEKAVFNTQKRENAEENNCDYNEFGRTLCDS 258

Query: 284 LPLRCFQEGCS----YAAPDRKAFI---KHLKETHGVRAVECRHHSCP------MLFATA 330
             L   Q   S    Y   D + F+     L + HGV     +H+ C             
Sbjct: 259 SSLLFHQISPSRDNHYEFSDCEKFLCVKSTLSKPHGV---SMKHYDCGESGNNFRRKLCL 315

Query: 331 EAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDH 390
             ++   K    F C  C  A   K    +H++  H G +  +C  C  A ++      H
Sbjct: 316 SHLQKGDKGEKHFECNECGKAFWEKSHLTRHQRV-HTGQKPFQCNECEKAFWDKSNLTKH 374

Query: 391 VGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLT 450
             + H  EK  +C EC  A +HK  L  H   HTGEKP++C  C  T    S L+KH  T
Sbjct: 375 Q-RSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRT 433

Query: 451 HSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG- 509
           H+  K Y C ECG   +   +L+VH R H G+  ++C +C         L+ H+  H G 
Sbjct: 434 HTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGD 493

Query: 510 KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTR 569
           KS  C  C      K  L +H     H G     Y C+ C      K  +  H+   HT 
Sbjct: 494 KSYECNACGKTFYHKSLLTRHQII--HTGWKP--YECYECGKTFCLKSDLTVHQR-THTG 548

Query: 570 LREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + F C  C       +TL  H R   G  P
Sbjct: 549 QKPFACPECGKFFSHKSTLSQHYRTHTGEKP 579



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 50/212 (23%), Positives = 75/212 (35%), Gaps = 25/212 (11%)

Query: 1470 HSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTK 1529
            H +I T E  +   +C     + +      R + EE      E G      + L +H   
Sbjct: 208  HEKIQTLEHNFEYSICQETLLEKAVFNTQKRENAEENNCDYNEFGRTLCDSSSLLFHQIS 267

Query: 1530 HTGLKPYQCPECEY--------------------CTNRADALR-----VHQETRHREARA 1564
             +    Y+  +CE                     C    +  R      H +   +  + 
Sbjct: 268  PSRDNHYEFSDCEKFLCVKSTLSKPHGVSMKHYDCGESGNNFRRKLCLSHLQKGDKGEKH 327

Query: 1565 FMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCR 1624
            F C +CGKAF  +  L  H R H+  KP+ CN C +AF   + L  H  +HT   PF C 
Sbjct: 328  FECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECN 387

Query: 1625 LCNYKAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
             C      K  +  H R H  ++       GK
Sbjct: 388  ECGKAFSHKSALTLHQRTHTGEKPYQCNACGK 419



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 37/135 (27%), Positives = 54/135 (40%), Gaps = 6/135 (4%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T +  K + C EC + F  ++ L+ H   H  +   +C  C KFF  KS L  H     G
Sbjct: 657 THTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRAHTG 716

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           EK+  C  C      ++ L +H  S   +        Y C  CR+ F     L  H + H
Sbjct: 717 EKSCQCNECGKIFYRKSELAQHQRSHTGE------KPYECNTCRKTFSQKSNLIVHQRRH 770

Query: 276 TAAAAAEPLPLRCFQ 290
                   + +R FQ
Sbjct: 771 IGENLMNEMDIRNFQ 785



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C      + AL +H RT  Q   +P  C ECG SF  + GL  H
Sbjct: 634 KPYKCNECGKAFCHKSALIVHQRTHTQ--EKPYKCNECGKSFCVKSGLIFH 682



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + F C  C      + AL LH RT      +P  C  CG +F Q+  L+ H
Sbjct: 382 KPFECNECGKAFSHKSALTLHQRT--HTGEKPYQCNACGKTFCQKSDLTKH 430



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    + + C  C      +  L +H RT     ++P  CPECG  F  +  LS H
Sbjct: 516 IIHTGWKPYECYECGKTFCLKSDLTVHQRT--HTGQKPFACPECGKFFSHKSTLSQH 570



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + + C  C    R    L +H RT      +P  C ECG SF ++  L+ H
Sbjct: 438 KPYECYECGKSFRVTSHLKVHQRT--HTGEKPFECLECGKSFSEKSNLTQH 486


>gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]
          Length = 811

 Score =  231 bits (589), Expect = 4e-60
 Identities = 145/480 (30%), Positives = 204/480 (42%), Gaps = 42/480 (8%)

Query: 1170 HLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIP 1229
            H +C +CG    +   + +H+R+ H G KP QC  C+ +   +  L  HQ  HTG     
Sbjct: 328  HFECNECGKAFWEKSHLTRHQRV-HTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFE 386

Query: 1230 CSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACS 1289
            C+ C + F   S L LH+ R H     + C  C  +   + D+T+H  + H G   + C 
Sbjct: 387  CNECGKAFSHKSALTLHQ-RTHTGEKPYQCNACGKTFCQKSDLTKHQRT-HTGLKPYECY 444

Query: 1290 QCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRK 1349
            +C   F   + LK H  R H             T E P  C  CG      ++L  H R 
Sbjct: 445  ECGKSFRVTSHLKVHQ-RTH-------------TGEKPFECLECGKSFSEKSNLTQHQRI 490

Query: 1350 Q--HPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKHYLEQHEE 1405
                   EC AC + F  +  L  H+        + C  C      +   +K  L  H+ 
Sbjct: 491  HIGDKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECG-----KTFCLKSDLTVHQR 545

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T             GQ P  CP C     H+  L  H + H G + Y+C +C     N+ 
Sbjct: 546  THT-----------GQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKS 594

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T H+R HTGEKPY C+ C  A    S+L  H RIH  E+ Y C ECG      + L  
Sbjct: 595  YLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIV 654

Query: 1526 HMTKHTGLKPYQCPEC--EYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTH 1583
            H   HT  KPY+C EC   +C        +  E +H   + + C +CGK F+ +  L  H
Sbjct: 655  HQRTHTQEKPYKCNECGKSFCVKSG---LIFHERKHTGEKPYECNECGKFFRHKSSLTVH 711

Query: 1584 LRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             R H+  K   CN C + F   + L  H  +HT   P+ C  C     QK  ++ H RRH
Sbjct: 712  HRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRH 771



 Score =  192 bits (487), Expect = 3e-48
 Identities = 155/554 (27%), Positives = 222/554 (40%), Gaps = 54/554 (9%)

Query: 1111 FSCQQERALRTHQIRGCPLEESGELHCSLCPF--TAPAATALRLHQKRRHPTAAPARGPR 1168
            +S  QE  L          E + E +C    F  T   +++L  HQ       +P+R   
Sbjct: 221  YSICQETLLEKAVFNTQKRENAEENNCDYNEFGRTLCDSSSLLFHQ------ISPSRDN- 273

Query: 1169 PHLQCGDCG-FTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGR 1227
             H +  DC  F C +S   + H       +K + C     +  R+  L   Q    G   
Sbjct: 274  -HYEFSDCEKFLCVKSTLSKPHG----VSMKHYDCGESGNNFRRKLCLSHLQKGDKGEKH 328

Query: 1228 IPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFA 1287
              C+ C + F   S L  H+ RVH       C  C+ + + + ++T+H  S H G   F 
Sbjct: 329  FECNECGKAFWEKSHLTRHQ-RVHTGQKPFQCNECEKAFWDKSNLTKHQRS-HTGEKPFE 386

Query: 1288 CSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT 1347
            C++C   FS ++AL  H  R H             T E P  C+ CG      + L  H 
Sbjct: 387  CNECGKAFSHKSALTLHQ-RTH-------------TGEKPYQCNACGKTFCQKSDLTKHQ 432

Query: 1348 RKQHPRL---ECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQ 1402
            R  H  L   EC  C ++F     L  H+R         C  C  +  E+  L +H    
Sbjct: 433  RT-HTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH 491

Query: 1403 HEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTK 1462
                             G     C  C  T  H+ +L  H   H G + Y+C +C  +  
Sbjct: 492  ----------------IGDKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFC 535

Query: 1463 NRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQ 1522
             +  +T H R HTG+KP+ C  C    +  S L  H R H  E+ Y C ECG      + 
Sbjct: 536  LKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSY 595

Query: 1523 LKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRT 1582
            L  H   HTG KPY+C EC     +   L  HQ   H   + + C +CGKAF  +  L  
Sbjct: 596  LTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRI-HIGEKPYKCNECGKAFCHKSALIV 654

Query: 1583 HLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRR 1642
            H R H++ KPY CN C ++F   +GL  H   HT   P+ C  C    + K  +  H R 
Sbjct: 655  HQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRA 714

Query: 1643 HHPDQADPNQGVGK 1656
            H  +++      GK
Sbjct: 715  HTGEKSCQCNECGK 728



 Score =  179 bits (454), Expect = 2e-44
 Identities = 122/433 (28%), Positives = 179/433 (41%), Gaps = 49/433 (11%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC++ F  +++L +H   H  +   +C  C K F+ KS L  H     GEK + 
Sbjct: 355 KPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQ 414

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L +H  + H  +       Y C  C + FR++  LK H ++HT    
Sbjct: 415 CNACGKTFCQKSDLTKHQRT-HTGLK-----PYECYECGKSFRVTSHLKVHQRTHTGEK- 467

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC--------------RH------ 320
               P  C + G S++  ++    +H +   G ++ EC              RH      
Sbjct: 468 ----PFECLECGKSFS--EKSNLTQHQRIHIGDKSYECNACGKTFYHKSLLTRHQIIHTG 521

Query: 321 ------HSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEE 371
                 + C   F     +  H ++H     F CP C    S+K    +H +  H G + 
Sbjct: 522 WKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRT-HTGEKP 580

Query: 372 LRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKC 431
             C  C    +N  +Y     + H  EK ++C EC  A   K  L +H  +H GEKP+KC
Sbjct: 581 YECHECGKIFYNK-SYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKC 639

Query: 432 ELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCS 491
             C       S L  H  TH+  K Y C ECG     K  L  H RKH G+  Y+CN+C 
Sbjct: 640 NECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECG 699

Query: 492 YRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCS 550
                   L+ H   H G KS  C  C     RK EL +H  S  H G     Y C+ C 
Sbjct: 700 KFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRS--HTGEKP--YECNTCR 755

Query: 551 YQSRHKQAVLSHE 563
                K  ++ H+
Sbjct: 756 KTFSQKSNLIVHQ 768



 Score =  178 bits (452), Expect = 3e-44
 Identities = 126/441 (28%), Positives = 183/441 (41%), Gaps = 28/441 (6%)

Query: 165 CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLC 224
           C EC + F +++HL  H  +H      QC  C+K F  KS L  H     GEK   C  C
Sbjct: 331 CNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNEC 390

Query: 225 HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPL 284
             +   ++AL  H        ++     Y C  C + F     L +H ++HT        
Sbjct: 391 GKAFSHKSALTLHQR------THTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLK----- 439

Query: 285 PLRCFQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAHHKSHY-- 341
           P  C++ G S+      + +K  + TH G +  EC    C   F+    +  H + H   
Sbjct: 440 PYECYECGKSFRV---TSHLKVHQRTHTGEKPFECL--ECGKSFSEKSNLTQHQRIHIGD 494

Query: 342 -AFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
            ++ C  C     +K L  +H+   H G +   C  C   TF   +      + H  +K 
Sbjct: 495 KSYECNACGKTFYHKSLLTRHQII-HTGWKPYECYECG-KTFCLKSDLTVHQRTHTGQKP 552

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
             CPEC    +HK  L +H   HTGEKP++C  C     + SYL+KH  TH+  K Y C 
Sbjct: 553 FACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECN 612

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYR-CHRADQLSSHKLRHQGKSLMCEVCAF 519
           ECG     K  L  H R H G+  Y+CN+C    CH++  +   +   Q K   C  C  
Sbjct: 613 ECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGK 672

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           +   K  L  H   + H G     Y C+ C    RHK ++  H    HT  +   C  C 
Sbjct: 673 SFCVKSGLIFH--ERKHTGEKP--YECNECGKFFRHKSSLTVHHRA-HTGEKSCQCNECG 727

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
              +  + L  H+R   G  P
Sbjct: 728 KIFYRKSELAQHQRSHTGEKP 748



 Score =  163 bits (412), Expect = 2e-39
 Identities = 105/364 (28%), Positives = 157/364 (43%), Gaps = 20/364 (5%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T +  K + C EC + F+  +HL  H   H  +   +C  C K F+ KS L  H    +G
Sbjct: 434 THTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIG 493

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           +K++ C  C  +   ++ L RH       I +     Y C  C + F L   L  H ++H
Sbjct: 494 DKSYECNACGKTFYHKSLLTRHQ------IIHTGWKPYECYECGKTFCLKSDLTVHQRTH 547

Query: 276 TAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEA 335
           T        P  C +  C      +    +H +   G +  EC  H C  +F     +  
Sbjct: 548 TGQK-----PFACPE--CGKFFSHKSTLSQHYRTHTGEKPYEC--HECGKIFYNKSYLTK 598

Query: 336 HHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVG 392
           H+++H     + C  C  A   K    +H++  H G +  +C  C  A  +  A   H  
Sbjct: 599 HNRTHTGEKPYECNECGKAFYQKSQLTQHQRI-HIGEKPYKCNECGKAFCHKSALIVHQ- 656

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           + H  EK ++C EC  +   K  LI H   HTGEKP++C  C    R  S L+ H   H+
Sbjct: 657 RTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRAHT 716

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSL 512
             K   C ECG +   K  L  H R H G+  Y+CN C     +   L  H+ RH G++L
Sbjct: 717 GEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRHIGENL 776

Query: 513 MCEV 516
           M E+
Sbjct: 777 MNEM 780



 Score =  148 bits (374), Expect = 4e-35
 Identities = 117/435 (26%), Positives = 176/435 (40%), Gaps = 52/435 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +   + AL  HQ        +GE    C+ C  T    + L  HQ+      
Sbjct: 385  FECNECGKAFSHKSALTLHQ-----RTHTGEKPYQCNACGKTFCQKSDLTKHQRTH---- 435

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG + + +  ++ H+R  H G KP +C  C  S + +  L  HQ  
Sbjct: 436  ---TGLKPY-ECYECGKSFRVTSHLKVHQRT-HTGEKPFECLECGKSFSEKSNLTQHQRI 490

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            H G     C++C +TF   S L  H++ +H     + C  C  +  L+ D+T H  + H 
Sbjct: 491  HIGDKSYECNACGKTFYHKSLLTRHQI-IHTGWKPYECYECGKTFCLKSDLTVHQRT-HT 548

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   FAC +C   FS ++ L QH  R H             T E P  C  CG +  + +
Sbjct: 549  GQKPFACPECGKFFSHKSTLSQH-YRTH-------------TGEKPYECHECGKIFYNKS 594

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C +AF  +  L +H+R       ++C  C  A   +  L+ 
Sbjct: 595  YLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIV 654

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H     +E                 P  C  C  +   +  L  H + H G + Y+C +C
Sbjct: 655  HQRTHTQEK----------------PYKCNECGKSFCVKSGLIFHERKHTGEKPYECNEC 698

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
                +++  +T H R HTGEK   C+ C       S L  H R H  E+ Y C  C    
Sbjct: 699  GKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTF 758

Query: 1518 KWVNQLKYHMTKHTG 1532
               + L  H  +H G
Sbjct: 759  SQKSNLIVHQRRHIG 773



 Score =  124 bits (311), Expect = 8e-28
 Identities = 114/451 (25%), Positives = 167/451 (37%), Gaps = 53/451 (11%)

Query: 192 QCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVE-----------------RNAL 234
           QC +C   F + S+L    +  LG+K+     C    +                  RN L
Sbjct: 141 QCDSCGMSFNTVSELVISKINYLGKKSDEFNACGKLLLNIKHDETHTQEKNEVLKNRNTL 200

Query: 235 NRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAA-----------AAAEP 283
           + H  ++  +        +   +C+E   L +A+    K   A               + 
Sbjct: 201 SHHEETLQHEKIQTLEHNFEYSICQETL-LEKAVFNTQKRENAEENNCDYNEFGRTLCDS 259

Query: 284 LPLRCFQEGCS----YAAPDRKAFI---KHLKETHGVRAVECRHHSCP------MLFATA 330
             L   Q   S    Y   D + F+     L + HGV     +H+ C             
Sbjct: 260 SSLLFHQISPSRDNHYEFSDCEKFLCVKSTLSKPHGV---SMKHYDCGESGNNFRRKLCL 316

Query: 331 EAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDH 390
             ++   K    F C  C  A   K    +H++  H G +  +C  C  A ++      H
Sbjct: 317 SHLQKGDKGEKHFECNECGKAFWEKSHLTRHQRV-HTGQKPFQCNECEKAFWDKSNLTKH 375

Query: 391 VGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLT 450
             + H  EK  +C EC  A +HK  L  H   HTGEKP++C  C  T    S L+KH  T
Sbjct: 376 Q-RSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRT 434

Query: 451 HSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG- 509
           H+  K Y C ECG   +   +L+VH R H G+  ++C +C         L+ H+  H G 
Sbjct: 435 HTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGD 494

Query: 510 KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTR 569
           KS  C  C      K  L +H     H G     Y C+ C      K  +  H+   HT 
Sbjct: 495 KSYECNACGKTFYHKSLLTRHQII--HTGWKP--YECYECGKTFCLKSDLTVHQR-THTG 549

Query: 570 LREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + F C  C       +TL  H R   G  P
Sbjct: 550 QKPFACPECGKFFSHKSTLSQHYRTHTGEKP 580



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 50/212 (23%), Positives = 75/212 (35%), Gaps = 25/212 (11%)

Query: 1470 HSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTK 1529
            H +I T E  +   +C     + +      R + EE      E G      + L +H   
Sbjct: 209  HEKIQTLEHNFEYSICQETLLEKAVFNTQKRENAEENNCDYNEFGRTLCDSSSLLFHQIS 268

Query: 1530 HTGLKPYQCPECEY--------------------CTNRADALR-----VHQETRHREARA 1564
             +    Y+  +CE                     C    +  R      H +   +  + 
Sbjct: 269  PSRDNHYEFSDCEKFLCVKSTLSKPHGVSMKHYDCGESGNNFRRKLCLSHLQKGDKGEKH 328

Query: 1565 FMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCR 1624
            F C +CGKAF  +  L  H R H+  KP+ CN C +AF   + L  H  +HT   PF C 
Sbjct: 329  FECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECN 388

Query: 1625 LCNYKAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
             C      K  +  H R H  ++       GK
Sbjct: 389  ECGKAFSHKSALTLHQRTHTGEKPYQCNACGK 420



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 37/135 (27%), Positives = 54/135 (40%), Gaps = 6/135 (4%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T +  K + C EC + F  ++ L+ H   H  +   +C  C KFF  KS L  H     G
Sbjct: 658 THTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRAHTG 717

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           EK+  C  C      ++ L +H  S   +        Y C  CR+ F     L  H + H
Sbjct: 718 EKSCQCNECGKIFYRKSELAQHQRSHTGE------KPYECNTCRKTFSQKSNLIVHQRRH 771

Query: 276 TAAAAAEPLPLRCFQ 290
                   + +R FQ
Sbjct: 772 IGENLMNEMDIRNFQ 786



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C      + AL +H RT  Q   +P  C ECG SF  + GL  H
Sbjct: 635 KPYKCNECGKAFCHKSALIVHQRTHTQ--EKPYKCNECGKSFCVKSGLIFH 683



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + F C  C      + AL LH RT      +P  C  CG +F Q+  L+ H
Sbjct: 383 KPFECNECGKAFSHKSALTLHQRT--HTGEKPYQCNACGKTFCQKSDLTKH 431



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    + + C  C      +  L +H RT     ++P  CPECG  F  +  LS H
Sbjct: 517 IIHTGWKPYECYECGKTFCLKSDLTVHQRT--HTGQKPFACPECGKFFSHKSTLSQH 571



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + + C  C    R    L +H RT      +P  C ECG SF ++  L+ H
Sbjct: 439 KPYECYECGKSFRVTSHLKVHQRT--HTGEKPFECLECGKSFSEKSNLTQH 487


>gi|22095393 zinc finger protein 420 [Homo sapiens]
          Length = 688

 Score =  231 bits (588), Expect = 6e-60
 Identities = 165/565 (29%), Positives = 236/565 (41%), Gaps = 63/565 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  ++  L  HQ        +GE    C  C      ++ L LH +      
Sbjct: 167  YECKQCGKAFSRDSQLSLHQRL-----HTGEKPYACKECGKAFTQSSQLILHHRIH---- 217

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG    +S  + +H+++ H G KP++C  C  + T+  +L  HQ  
Sbjct: 218  ---TGEKPY-KCEECGKAFIRSSQLTRHQKV-HTGEKPYECKECGKAFTQNSQLTLHQRL 272

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L LH+ R+H     + C  C  +      +++H    H 
Sbjct: 273  HTGEKLYECKECRKVFTQLSQLILHK-RIHTGEKPYECKECGKAFICGSQLSQH-QKIHN 330

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C   F   + L QH  R H             T E P  C  CG      A
Sbjct: 331  GEKPYECKECGRAFIRGSLLMQHQ-RIH-------------TGEKPYKCEECG-----KA 371

Query: 1342 SLRGHTRKQHPRL-------ECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARER 1392
             +RG    QH R+       EC  C + F     L +H+R       ++C+ C  A    
Sbjct: 372  FIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRG 431

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
              L +H   Q   T             G+ P  C  C  T      L  H + H G + Y
Sbjct: 432  SLLTRH---QRIHT-------------GEKPYECKECGKTFSRGSELTQHERIHTGEKPY 475

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            +C +C  S     ++T H RIHTGEKPY C  C  A    S L  H R+H  E+ Y+C E
Sbjct: 476  ECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNE 535

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG        L  H   HTG KPYQC EC     R   L  HQ   H   + + C++CGK
Sbjct: 536  CGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRI-HTGEKPYECKECGK 594

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            AF     L  H R H+  KPY C  C +AF  ++ L  H   HT   P+ C+ C     +
Sbjct: 595  AFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTR 654

Query: 1633 KFQVVKHVRRHHPDQADPNQGVGKD 1657
              Q+ +H R H  +++   +  G D
Sbjct: 655  GSQLTQHQRIHISEKSFEYKECGID 679



 Score =  224 bits (570), Expect = 7e-58
 Identities = 147/491 (29%), Positives = 204/491 (41%), Gaps = 40/491 (8%)

Query: 1172 QCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCS 1231
            +C +CG   +++  + QH+ + H G KP++C  C  + +R  +L  HQ  HTG     C 
Sbjct: 140  KCKECGKAFRRASHLTQHQSI-HTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACK 198

Query: 1232 SCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQC 1291
             C + F  +S+L LH  R+H     + C  C  +      +TRH    H G   + C +C
Sbjct: 199  ECGKAFTQSSQLILHH-RIHTGEKPYKCEECGKAFIRSSQLTRH-QKVHTGEKPYECKEC 256

Query: 1292 EAQFSSETALKQHALRRH---------------PEPAQPAPGSPAETTEGPLHCSRCG-- 1334
               F+  + L  H  R H                + +Q        T E P  C  CG  
Sbjct: 257  GKAFTQNSQLTLHQ-RLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKA 315

Query: 1335 LLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRR--QQHFSHRCQLCDFAARER 1392
             +C S  S            EC  C  AF     L +H+R       ++C+ C  A    
Sbjct: 316  FICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRG 375

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
              L +H   Q   T+             + P  C  C     H   L  H + H G + Y
Sbjct: 376  SQLTQH---QRIHTN-------------EKPYECKECGKMFSHGSQLTQHQRIHTGEKPY 419

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            +C +C  +      +T H RIHTGEKPY C  C    +  S L  H RIH  E+ Y C E
Sbjct: 420  QCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKE 479

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG      +QL  H   HTG KPY+C EC     ++  L  HQ   H   + ++C +CGK
Sbjct: 480  CGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRL-HTGEKPYVCNECGK 538

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            AF    LL  H R H+  KPY C  C +AF   + L  H   HT   P+ C+ C      
Sbjct: 539  AFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSH 598

Query: 1633 KFQVVKHVRRH 1643
              Q+  H R H
Sbjct: 599  GSQLTLHQRIH 609



 Score =  178 bits (451), Expect = 5e-44
 Identities = 141/483 (29%), Positives = 196/483 (40%), Gaps = 65/483 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH-CSLCPFTAPAATALRLHQKRRHPTAA 1162
            + C  C  +  Q   L  HQ     L    +L+ C  C       + L LH KR H    
Sbjct: 251  YECKECGKAFTQNSQLTLHQ----RLHTGEKLYECKECRKVFTQLSQLILH-KRIHT--- 302

Query: 1163 PARGPRPHLQCGDCG--FTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQS 1220
               G +P+ +C +CG  F C     + QH+++ H G KP++C  C  +  R   L  HQ 
Sbjct: 303  ---GEKPY-ECKECGKAFICGSQ--LSQHQKI-HNGEKPYECKECGRAFIRGSLLMQHQR 355

Query: 1221 RHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCH 1280
             HTG     C  C + F   S+L  H+ R+H     + C  C         +T+H    H
Sbjct: 356  IHTGEKPYKCEECGKAFIRGSQLTQHQ-RIHTNEKPYECKECGKMFSHGSQLTQH-QRIH 413

Query: 1281 QGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSP 1340
             G   + C +C   F+  + L +H  R H             T E P  C  CG      
Sbjct: 414  TGEKPYQCKECGKAFNRGSLLTRHQ-RIH-------------TGEKPYECKECG-----K 454

Query: 1341 ASLRGHTRKQHPRL-------ECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARE 1391
               RG    QH R+       EC  C ++F     L +H+R       + C+ C  A  +
Sbjct: 455  TFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQ 514

Query: 1392 RVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRL 1451
                   +L QH+               G+ P  C  C       L+L  H + H G + 
Sbjct: 515  -----SSHLSQHQRLHT-----------GEKPYVCNECGKAFARGLLLIQHQRIHTGEKP 558

Query: 1452 YKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCP 1511
            Y+C +C  +     ++T H RIHTGEKPY C  C  A +  S+L  H RIH  E+ Y C 
Sbjct: 559  YQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPYECR 618

Query: 1512 ECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCG 1571
            EC       + L  H   HTG KPYQC EC     R   L  HQ   H   ++F  ++CG
Sbjct: 619  ECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRI-HISEKSFEYKECG 677

Query: 1572 KAF 1574
              F
Sbjct: 678  IDF 680



 Score =  170 bits (431), Expect = 9e-42
 Identities = 121/437 (27%), Positives = 177/437 (40%), Gaps = 26/437 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + + L  H  LH  +   +C  C+K FT  S+L  H     GEK + 
Sbjct: 249 KPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYE 308

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  + +  + L     S H+ I N     Y C  C   F     L +H + HT    
Sbjct: 309 CKECGKAFICGSQL-----SQHQKIHNG-EKPYECKECGRAFIRGSLLMQHQRIHTGEK- 361

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C  E C  A        +H +     +  EC+   C  +F+    +  H + H
Sbjct: 362 ----PYKC--EECGKAFIRGSQLTQHQRIHTNEKPYECKE--CGKMFSHGSQLTQHQRIH 413

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A +   L  +H++  H G +   C  C   TF+  +      ++H  
Sbjct: 414 TGEKPYQCKECGKAFNRGSLLTRHQRI-HTGEKPYECKECG-KTFSRGSELTQHERIHTG 471

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  +      L +H  +HTGEKP++C+ C       S+LS+H   H+  K Y
Sbjct: 472 EKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPY 531

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
           +C ECG        L  H R H G+  YQC +C     R  QL+ H+  H G K   C+ 
Sbjct: 532 VCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKE 591

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A     +L  H    H    P     C     QS H    LS     HT  + + C 
Sbjct: 592 CGKAFSHGSQLTLHQRI-HTGEKPYECRECRKAFTQSSH----LSRHQRIHTGEKPYQCK 646

Query: 577 LCDYRTFSNTTLLFHKR 593
            C       + L  H+R
Sbjct: 647 ECGKAFTRGSQLTQHQR 663



 Score =  169 bits (428), Expect = 2e-41
 Identities = 114/381 (29%), Positives = 152/381 (39%), Gaps = 39/381 (10%)

Query: 1269 RHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPL 1328
            +H      + CH     + C +C   F   + L QH                  T E P 
Sbjct: 122  QHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQH--------------QSIHTGEKPY 167

Query: 1329 HCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEAFP--SRLALDEHRRQQHFSHRCQL 1384
             C +CG      + L  H R         C  C +AF   S+L L          ++C+ 
Sbjct: 168  ECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEE 227

Query: 1385 CDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCD--FTCRHQLVLDHH 1442
            C  A      L +H   Q   T             G+ P  C  C   FT   QL L  H
Sbjct: 228  CGKAFIRSSQLTRH---QKVHT-------------GEKPYECKECGKAFTQNSQLTL--H 269

Query: 1443 VKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIH 1502
             + H G +LY+C +C        ++  H RIHTGEKPY C  C  A    S+L  H +IH
Sbjct: 270  QRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIH 329

Query: 1503 KEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREA 1562
              E+ Y C ECG      + L  H   HTG KPY+C EC     R   L  HQ   H   
Sbjct: 330  NGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRI-HTNE 388

Query: 1563 RAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFF 1622
            + + C++CGK F     L  H R H+  KPY C  C +AF   + L  H   HT   P+ 
Sbjct: 389  KPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYE 448

Query: 1623 CRLCNYKAKQKFQVVKHVRRH 1643
            C+ C     +  ++ +H R H
Sbjct: 449  CKECGKTFSRGSELTQHERIH 469



 Score =  165 bits (417), Expect = 4e-40
 Identities = 130/490 (26%), Positives = 192/490 (39%), Gaps = 45/490 (9%)

Query: 115 QETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKK 174
           +E+   + +E + K + Q+++QK   +       +G ++    S+F  H           
Sbjct: 82  EESNSRDYLEAKGKMEKQQENQKEYFR-------QGMIIYDKMSIFNQH----------- 123

Query: 175 RTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNAL 234
            T+L +H   H  +   +C  C K F   S L  H     GEK + C  C  +    + L
Sbjct: 124 -TYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQL 182

Query: 235 NRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCS 294
           + H   +H          YAC  C + F  S  L  H + HT        P +C  E C 
Sbjct: 183 SLHQR-LHTG-----EKPYACKECGKAFTQSSQLILHHRIHTGEK-----PYKC--EECG 229

Query: 295 YAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFA 351
            A        +H K   G +  EC+   C   F     +  H + H     + C  C   
Sbjct: 230 KAFIRSSQLTRHQKVHTGEKPYECKE--CGKAFTQNSQLTLHQRLHTGEKLYECKECRKV 287

Query: 352 CSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATA 411
            +       HK+  H G +   C  C  A         H  K+H  EK ++C EC  A  
Sbjct: 288 FTQLSQLILHKRI-HTGEKPYECKECGKAFICGSQLSQHQ-KIHNGEKPYECKECGRAFI 345

Query: 412 HKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHY 471
              +L++H  +HTGEKP+KCE C       S L++H   H+N K Y C ECG +      
Sbjct: 346 RGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQ 405

Query: 472 LRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKH 530
           L  H R H G+  YQC +C    +R   L+ H+  H G K   C+ C     R  EL +H
Sbjct: 406 LTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQH 465

Query: 531 MASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLF 590
              + H G     Y C  C         +  H+   HT  + + C  C      ++ L  
Sbjct: 466 --ERIHTGEKP--YECKECGKSFIRGSQLTQHQRI-HTGEKPYECKECRMAFTQSSHLSQ 520

Query: 591 HKRKAHGYVP 600
           H+R   G  P
Sbjct: 521 HQRLHTGEKP 530



 Score =  142 bits (359), Expect = 2e-33
 Identities = 81/258 (31%), Positives = 112/258 (43%), Gaps = 12/258 (4%)

Query: 1399 YLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCA 1458
            YL QH    +            + P  C  C    R    L  H   H G + Y+C  C 
Sbjct: 125  YLSQHSRCHST-----------EKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCG 173

Query: 1459 YSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCK 1518
             +     +++ H R+HTGEKPY C  C  A    S+L  H RIH  E+ Y C ECG    
Sbjct: 174  KAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFI 233

Query: 1519 WVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRF 1578
              +QL  H   HTG KPY+C EC     +   L +HQ   H   + + C++C K F    
Sbjct: 234  RSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRL-HTGEKLYECKECRKVFTQLS 292

Query: 1579 LLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVK 1638
             L  H R H+  KPY C  C +AF   + L  H   H    P+ C+ C     +   +++
Sbjct: 293  QLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQ 352

Query: 1639 HVRRHHPDQADPNQGVGK 1656
            H R H  ++    +  GK
Sbjct: 353  HQRIHTGEKPYKCEECGK 370



 Score =  140 bits (354), Expect = 8e-33
 Identities = 97/380 (25%), Positives = 158/380 (41%), Gaps = 25/380 (6%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFK 173
           G + ++ + +   EK    K+  +A  +G    + +  + +G     K + C EC + F 
Sbjct: 319 GSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQR-IHTGE----KPYKCEECGKAFI 373

Query: 174 KRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNA 233
           + + L +H  +H  +   +C  C K F+  S+L  H     GEK + C  C  +    + 
Sbjct: 374 RGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSL 433

Query: 234 LNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGC 293
           L RH   +H          Y C  C + F     L +H + HT        P  C + G 
Sbjct: 434 LTRHQR-IHTG-----EKPYECKECGKTFSRGSELTQHERIHTGEK-----PYECKECGK 482

Query: 294 SYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDF 350
           S+    +    +H +   G +  EC+   C M F  +  +  H + H     + C  C  
Sbjct: 483 SFIRGSQ--LTQHQRIHTGEKPYECKE--CRMAFTQSSHLSQHQRLHTGEKPYVCNECGK 538

Query: 351 ACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFAT 410
           A +   L  +H++  H G +  +C  C  A         H  ++H  EK ++C EC  A 
Sbjct: 539 AFARGLLLIQHQRI-HTGEKPYQCKECGKAFIRGSQLTQHQ-RIHTGEKPYECKECGKAF 596

Query: 411 AHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKH 470
           +H   L  H  +HTGEKP++C  C       S+LS+H   H+  K Y C ECG       
Sbjct: 597 SHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGS 656

Query: 471 YLRVHMRKHAGDLRYQCNQC 490
            L  H R H  +  ++  +C
Sbjct: 657 QLTQHQRIHISEKSFEYKEC 676



 Score =  140 bits (352), Expect = 1e-32
 Identities = 93/350 (26%), Positives = 140/350 (40%), Gaps = 20/350 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F + + L++H  +H  +   +C  C K F   S+L  H      EK + 
Sbjct: 333 KPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYE 392

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C       + L +H   +H          Y C  C + F     L  H + HT    
Sbjct: 393 CKECGKMFSHGSQLTQHQR-IHTG-----EKPYQCKECGKAFNRGSLLTRHQRIHTGEK- 445

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C + G +++        +H +   G +  EC+   C   F     +  H + H
Sbjct: 446 ----PYECKECGKTFSRGSE--LTQHERIHTGEKPYECKE--CGKSFIRGSQLTQHQRIH 497

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A +      +H++  H G +   C  C  A    +    H  ++H  
Sbjct: 498 TGEKPYECKECRMAFTQSSHLSQHQRL-HTGEKPYVCNECGKAFARGLLLIQHQ-RIHTG 555

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK +QC EC  A      L +H  +HTGEKP++C+ C       S L+ H   H+  K Y
Sbjct: 556 EKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPY 615

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRH 507
            C EC        +L  H R H G+  YQC +C     R  QL+ H+  H
Sbjct: 616 ECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIH 665



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 26/70 (37%), Positives = 32/70 (45%)

Query: 1574 FKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQK 1633
            F     L  H R HS  KPY C  C +AFR A+ L  H   HT   P+ C+ C     + 
Sbjct: 120  FNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRD 179

Query: 1634 FQVVKHVRRH 1643
             Q+  H R H
Sbjct: 180  SQLSLHQRLH 189



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + + C  C     R+  L+LH R  TG     +P  C ECG +F Q   L  H
Sbjct: 165 KPYECKQCGKAFSRDSQLSLHQRLHTG----EKPYACKECGKAFTQSSQLILH 213


>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
            [Homo sapiens]
          Length = 738

 Score =  231 bits (588), Expect = 6e-60
 Identities = 160/546 (29%), Positives = 225/546 (41%), Gaps = 53/546 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  Q+    TH         +GE   +CS C       + L  HQ+      
Sbjct: 235  FGCGNCGKTFPQKSQFITHH-----RTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---- 285

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG+CG    +   +  H R  H G KP+ C  C  + + +  L  HQ  
Sbjct: 286  ---TGEKPY-ECGECGKAFSRKSHLISHWRT-HTGEKPYGCNECGRAFSEKSNLINHQRI 340

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L  H  R H  T    C  C  + + + ++ RH  + H 
Sbjct: 341  HTGEKPFECRECGKAFSRKSQLVTHH-RTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHT 398

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F   ++L  H  R H             T E P  C +CG      +
Sbjct: 399  GEKPYECSECRKAFRERSSLINHQ-RTH-------------TGEKPHGCIQCGKAFSQKS 444

Query: 1342 SLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H  T        C  C +AF  +  L  H+R       + C  C  A  E++ L  
Sbjct: 445  HLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTN 504

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C      +  L  H + H G + Y+C++C
Sbjct: 505  H---QRIHT-------------GEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              +   +  +  H R HTGEKPY C  C  A +  S+L  H RIH  E+ Y C  C    
Sbjct: 549  GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
               ++L  H+  HTG KPY+C EC        +L  HQ   H   + F C +CGKAF  +
Sbjct: 609  FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGEKPFECSECGKAFSRK 667

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  H R H+  KPY C+ C +AF   + L +H   HT   P+ C  C     QK Q++
Sbjct: 668  SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 1638 KHVRRH 1643
             H R H
Sbjct: 728  NHQRTH 733



 Score =  203 bits (516), Expect = 1e-51
 Identities = 137/467 (29%), Positives = 194/467 (41%), Gaps = 39/467 (8%)

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
            K+S+ +  HR     G K ++C  C    +++  L  HQSRH       C +C +TF   
Sbjct: 190  KKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQK 247

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S+   H  R H     + C  C  +   +  +T H  + H G   + C +C   FS ++ 
Sbjct: 248  SQFITHH-RTHTGEKPYNCSQCGKAFSQKSQLTSHQRT-HTGEKPYECGECGKAFSRKSH 305

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
            L  H  R H             T E P  C+ CG      ++L  H R        EC  
Sbjct: 306  LISH-WRTH-------------TGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351

Query: 1359 CQEAFPSRLALDEHRRQQHFSHR--CQLCDFAARERVGLVKHYLEQHEETSAAVAASDGD 1416
            C +AF  +  L  H R    +    C  C  A  E+  L++H                  
Sbjct: 352  CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH-------------- 397

Query: 1417 GDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTG 1476
               G+ P  C  C    R +  L +H + H G + + C  C  +   +  +  H   HTG
Sbjct: 398  --TGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG 455

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            EKP+ C  C  A +  S+L  H R H  E+ Y C ECG        L  H   HTG KPY
Sbjct: 456  EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPY 515

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
             C EC     +   L  HQ T H   + + C +CGKAF  +  L TH R H+  KPY C 
Sbjct: 516  VCSECGKAFCQKSHLISHQRT-HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECR 574

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             C +AF   + L  H   HT   P+ C LC     +K ++++H+R H
Sbjct: 575  DCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTH 621



 Score =  190 bits (482), Expect = 1e-47
 Identities = 130/444 (29%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F K+  L++H   H  D +  C NC K F  KS+  TH     GEK ++
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYN 264

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L  H        ++     Y C  C + F     L  H ++HT    
Sbjct: 265 CSQCGKAFSQKSQLTSHQR------THTGEKPYECGECGKAFSRKSHLISHWRTHTGEK- 317

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++   I H +   G +  ECR   C   F+    +  HH++H
Sbjct: 318 ----PYGCNE--CGRAFSEKSNLINHQRIHTGEKPFECR--ECGKAFSRKSQLVTHHRTH 369

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  A   K    +H+   H G +   C+ C  A     +  +H  + H  
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTI-HTGEKPYECSECRKAFRERSSLINH-QRTHTG 427

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK H C +C  A + K  LI H + HTGEKP  C  C       S L +H  TH+  K Y
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y C++C     +   L SH+  H G K   C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K  L  H  +  H G     Y C  C      K  + +H+   HT  + + C+
Sbjct: 548 CGKAFGEKSSLATHQRT--HTGEKP--YECRDCEKAFSQKSQLNTHQRI-HTGEKPYECS 602

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           LC    F  + L+ H R   G  P
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKP 626



 Score =  180 bits (457), Expect = 9e-45
 Identities = 126/444 (28%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +++ L  H   H  +   +C  C K F+ KS L +H     GEK + 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L  H   +H     F      C  C + F     L  H ++HT    
Sbjct: 321 CNECGRAFSEKSNLINHQR-IHTGEKPF-----ECRECGKAFSRKSQLVTHHRTHTGTK- 373

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A  ++   I+H     G +  EC    C   F    ++  H ++H
Sbjct: 374 ----PFGC--SDCRKAFFEKSELIRHQTIHTGEKPYECSE--CRKAFRERSSLINHQRTH 425

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                  C  C  A S K     H+   H G +   C+ C  A         H  + H  
Sbjct: 426 TGEKPHGCIQCGKAFSQKSHLISHQMT-HTGEKPFICSKCGKAFSRKSQLVRHQ-RTHTG 483

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A + K  L  H  +HTGEKP+ C  C       S+L  H  TH+  K Y
Sbjct: 484 EKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPY 543

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y+C  C     +  QL++H+  H G K   C +
Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K EL +H+ +  H G     Y C+ C    R K ++++H+   HT  + F C+
Sbjct: 604 CRKAFFEKSELIRHLRT--HTGEKP--YECNECRKAFREKSSLINHQRI-HTGEKPFECS 658

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       + L+ H+R   G  P
Sbjct: 659 ECGKAFSRKSHLIPHQRTHTGEKP 682



 Score =  178 bits (451), Expect = 5e-44
 Identities = 121/440 (27%), Positives = 181/440 (41%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F ++++L+ H  +H  +   +C  C K F+ KS+L TH     G K   
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L RH  ++H          Y C  CR+ FR   +L  H ++HT    
Sbjct: 377 CSDCRKAFFEKSELIRHQ-TIHTG-----EKPYECSECRKAFRERSSLINHQRTHTGEK- 429

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C Q  C  A   +   I H     G +   C    C   F+    +  H ++H
Sbjct: 430 ----PHGCIQ--CGKAFSQKSHLISHQMTHTGEKPFICS--KCGKAFSRKSQLVRHQRTH 481

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S K     H++  H G +   C+ C  A         H  + H  
Sbjct: 482 TGEKPYECSECGKAFSEKLSLTNHQRI-HTGEKPYVCSECGKAFCQKSHLISHQ-RTHTG 539

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  L  H   HTGEKP++C  C+      S L+ H   H+  K Y
Sbjct: 540 EKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ C      K  L  H+R H G+  Y+CN+C         L +H+  H G K   C  
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A    +  + H+       T    Y C  C      K  +++H+   HT  + + C 
Sbjct: 660 CGKA----FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI-HTGEKPYRCI 714

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  + FS  + L + ++ H
Sbjct: 715 ECG-KAFSQKSQLINHQRTH 733



 Score =  163 bits (412), Expect = 2e-39
 Identities = 109/422 (25%), Positives = 177/422 (41%), Gaps = 22/422 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSG-TESLFKTHMCPECKRCF 172
           G+  +E+ N+   ++  T +   +  + G+   R    V    T +  K   C +C++ F
Sbjct: 325 GRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAF 384

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L+ H  +H  +   +C  C+K F  +S L  H     GEK H C  C  +  +++
Sbjct: 385 FEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKS 444

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H       +++     + C  C + F     L  H ++HT        P  C +  
Sbjct: 445 HLISHQ------MTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEK-----PYECSE-- 491

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A  ++ +   H +   G +   C    C   F     + +H ++H     + C  C 
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEKPYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A   K     H++  H G +   C  C  A         H  ++H  EK ++C  C  A
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQ-RIHTGEKPYECSLCRKA 607

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  LIRH+  HTGEKP++C  C    R+ S L  H   H+  K + C+ECG     K
Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRK 667

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
            +L  H R H G+  Y C++C     +  QL +H+  H G K   C  C  A  +K +L 
Sbjct: 668 SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 529 KH 530
            H
Sbjct: 728 NH 729



 Score =  162 bits (411), Expect = 2e-39
 Identities = 102/353 (28%), Positives = 150/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F++R+ L+ H   H  +    C  C K F+ KS L +H +   GEK   
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH  +   +        Y C  C + F    +L  H + HT    
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGE------KPYECSECGKAFSEKLSLTNHQRIHTGEK- 513

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A   +   I H +   G +  EC    C   F    ++  H ++H
Sbjct: 514 ----PYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSE--CGKAFGEKSSLATHQRTH 565

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C+ A S K     H++  H G +   C+ C  A F       H+ + H  
Sbjct: 566 TGEKPYECRDCEKAFSQKSQLNTHQRI-HTGEKPYECSLCRKAFFEKSELIRHL-RTHTG 623

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  LI H  +HTGEKP +C  C       S+L  H  TH+  K Y
Sbjct: 624 EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPY 683

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C+EC      K  L  H R H G+  Y+C +C     +  QL +H+  H  K
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVK 736



 Score =  149 bits (376), Expect = 2e-35
 Identities = 116/441 (26%), Positives = 174/441 (39%), Gaps = 44/441 (9%)

Query: 188 DPSLQCPNCQKFFTS--KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI 245
           D  L+  +C K+  S  KS++  +    LGEK + C  C     ++ +L +H +    DI
Sbjct: 174 DTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI 233

Query: 246 --------------SNFYS--------DTYACPVCREEFRLSQALKEHLKSHTAAAAAEP 283
                         S F +          Y C  C + F     L  H ++HT       
Sbjct: 234 AFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---- 289

Query: 284 LPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA- 342
            P  C +  C  A   +   I H +   G +   C  + C   F+    +  H + H   
Sbjct: 290 -PYECGE--CGKAFSRKSHLISHWRTHTGEKPYGC--NECGRAFSEKSNLINHQRIHTGE 344

Query: 343 --FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F C  C  A S K     H +  H G++   C+ C  A F       H   +H  EK 
Sbjct: 345 KPFECRECGKAFSRKSQLVTHHRT-HTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKP 402

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C EC  A   +  LI H   HTGEKPH C  C       S+L  H +TH+  K ++C+
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           +CG     K  L  H R H G+  Y+C++C         L++H+  H G K  +C  C  
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK 522

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +K     H+ S     T    Y C  C      K ++ +H+   HT  + + C  C+
Sbjct: 523 AFCQK----SHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCE 577

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                 + L  H+R   G  P
Sbjct: 578 KAFSQKSQLNTHQRIHTGEKP 598



 Score =  114 bits (284), Expect = 1e-24
 Identities = 82/326 (25%), Positives = 124/326 (38%), Gaps = 48/326 (14%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K H C +C + F +++HL+ H   H  +    C  C K F+ KS+L  H     GEK + 
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E+ +L  H   +H          Y C  C + F     L  H ++HT    
Sbjct: 489 CSECGKAFSEKLSLTNHQR-IHTG-----EKPYVCSECGKAFCQKSHLISHQRTHTGEK- 541

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++ +   H +   G +  ECR   C   F+    +  H + H
Sbjct: 542 ----PYECSE--CGKAFGEKSSLATHQRTHTGEKPYECR--DCEKAFSQKSQLNTHQRIH 593

Query: 341 YA-------------------------------FHCPHCDFACSNKHLFRKHKKQGHPGS 369
                                            + C  C  A   K     H++  H G 
Sbjct: 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGE 652

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C+ C  A F+  ++     + H  EK + C EC  A + K  L+ H  +HTGEKP+
Sbjct: 653 KPFECSECGKA-FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPY 711

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTK 455
           +C  C       S L  H  TH+  K
Sbjct: 712 RCIECGKAFSQKSQLINHQRTHTVKK 737



 Score =  107 bits (267), Expect = 1e-22
 Identities = 99/393 (25%), Positives = 147/393 (37%), Gaps = 48/393 (12%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  ++  L  HQ        +GE    CS C       ++L  HQ+      
Sbjct: 375  FGCSDCRKAFFEKSELIRHQTI-----HTGEKPYECSECRKAFRERSSLINHQRTH---- 425

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH  C  CG    Q   +  H+ + H G KP  C  C  + +R+ +L  HQ  
Sbjct: 426  ---TGEKPH-GCIQCGKAFSQKSHLISHQ-MTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F     L  H+ R+H     + C  C  +   +  +  H  + H 
Sbjct: 481  HTGEKPYECSECGKAFSEKLSLTNHQ-RIHTGEKPYVCSECGKAFCQKSHLISHQRT-HT 538

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +++L  H  R H             T E P  C  C       +
Sbjct: 539  GEKPYECSECGKAFGEKSSLATHQ-RTH-------------TGEKPYECRDCEKAFSQKS 584

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C++AF  +  L  H R       + C  C  A RE+  L+ 
Sbjct: 585  QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644

Query: 1398 HYL----EQHEETSAAVAASDGDGD--------AGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      E+  E S    A               G+ P  C  C      +  L +H + 
Sbjct: 645  HQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI 704

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
            H G + Y+C +C  +   + ++  H R HT +K
Sbjct: 705  HTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737


>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
            [Homo sapiens]
          Length = 738

 Score =  231 bits (588), Expect = 6e-60
 Identities = 160/546 (29%), Positives = 225/546 (41%), Gaps = 53/546 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  Q+    TH         +GE   +CS C       + L  HQ+      
Sbjct: 235  FGCGNCGKTFPQKSQFITHH-----RTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---- 285

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG+CG    +   +  H R  H G KP+ C  C  + + +  L  HQ  
Sbjct: 286  ---TGEKPY-ECGECGKAFSRKSHLISHWRT-HTGEKPYGCNECGRAFSEKSNLINHQRI 340

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L  H  R H  T    C  C  + + + ++ RH  + H 
Sbjct: 341  HTGEKPFECRECGKAFSRKSQLVTHH-RTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHT 398

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F   ++L  H  R H             T E P  C +CG      +
Sbjct: 399  GEKPYECSECRKAFRERSSLINHQ-RTH-------------TGEKPHGCIQCGKAFSQKS 444

Query: 1342 SLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H  T        C  C +AF  +  L  H+R       + C  C  A  E++ L  
Sbjct: 445  HLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTN 504

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C      +  L  H + H G + Y+C++C
Sbjct: 505  H---QRIHT-------------GEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              +   +  +  H R HTGEKPY C  C  A +  S+L  H RIH  E+ Y C  C    
Sbjct: 549  GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
               ++L  H+  HTG KPY+C EC        +L  HQ   H   + F C +CGKAF  +
Sbjct: 609  FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGEKPFECSECGKAFSRK 667

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  H R H+  KPY C+ C +AF   + L +H   HT   P+ C  C     QK Q++
Sbjct: 668  SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 1638 KHVRRH 1643
             H R H
Sbjct: 728  NHQRTH 733



 Score =  203 bits (516), Expect = 1e-51
 Identities = 137/467 (29%), Positives = 194/467 (41%), Gaps = 39/467 (8%)

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
            K+S+ +  HR     G K ++C  C    +++  L  HQSRH       C +C +TF   
Sbjct: 190  KKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQK 247

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S+   H  R H     + C  C  +   +  +T H  + H G   + C +C   FS ++ 
Sbjct: 248  SQFITHH-RTHTGEKPYNCSQCGKAFSQKSQLTSHQRT-HTGEKPYECGECGKAFSRKSH 305

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
            L  H  R H             T E P  C+ CG      ++L  H R        EC  
Sbjct: 306  LISH-WRTH-------------TGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351

Query: 1359 CQEAFPSRLALDEHRRQQHFSHR--CQLCDFAARERVGLVKHYLEQHEETSAAVAASDGD 1416
            C +AF  +  L  H R    +    C  C  A  E+  L++H                  
Sbjct: 352  CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH-------------- 397

Query: 1417 GDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTG 1476
               G+ P  C  C    R +  L +H + H G + + C  C  +   +  +  H   HTG
Sbjct: 398  --TGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG 455

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            EKP+ C  C  A +  S+L  H R H  E+ Y C ECG        L  H   HTG KPY
Sbjct: 456  EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPY 515

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
             C EC     +   L  HQ T H   + + C +CGKAF  +  L TH R H+  KPY C 
Sbjct: 516  VCSECGKAFCQKSHLISHQRT-HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECR 574

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             C +AF   + L  H   HT   P+ C LC     +K ++++H+R H
Sbjct: 575  DCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTH 621



 Score =  190 bits (482), Expect = 1e-47
 Identities = 130/444 (29%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F K+  L++H   H  D +  C NC K F  KS+  TH     GEK ++
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYN 264

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L  H        ++     Y C  C + F     L  H ++HT    
Sbjct: 265 CSQCGKAFSQKSQLTSHQR------THTGEKPYECGECGKAFSRKSHLISHWRTHTGEK- 317

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++   I H +   G +  ECR   C   F+    +  HH++H
Sbjct: 318 ----PYGCNE--CGRAFSEKSNLINHQRIHTGEKPFECR--ECGKAFSRKSQLVTHHRTH 369

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  A   K    +H+   H G +   C+ C  A     +  +H  + H  
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTI-HTGEKPYECSECRKAFRERSSLINH-QRTHTG 427

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK H C +C  A + K  LI H + HTGEKP  C  C       S L +H  TH+  K Y
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y C++C     +   L SH+  H G K   C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K  L  H  +  H G     Y C  C      K  + +H+   HT  + + C+
Sbjct: 548 CGKAFGEKSSLATHQRT--HTGEKP--YECRDCEKAFSQKSQLNTHQRI-HTGEKPYECS 602

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           LC    F  + L+ H R   G  P
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKP 626



 Score =  180 bits (457), Expect = 9e-45
 Identities = 126/444 (28%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +++ L  H   H  +   +C  C K F+ KS L +H     GEK + 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L  H   +H     F      C  C + F     L  H ++HT    
Sbjct: 321 CNECGRAFSEKSNLINHQR-IHTGEKPF-----ECRECGKAFSRKSQLVTHHRTHTGTK- 373

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A  ++   I+H     G +  EC    C   F    ++  H ++H
Sbjct: 374 ----PFGC--SDCRKAFFEKSELIRHQTIHTGEKPYECSE--CRKAFRERSSLINHQRTH 425

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                  C  C  A S K     H+   H G +   C+ C  A         H  + H  
Sbjct: 426 TGEKPHGCIQCGKAFSQKSHLISHQMT-HTGEKPFICSKCGKAFSRKSQLVRHQ-RTHTG 483

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A + K  L  H  +HTGEKP+ C  C       S+L  H  TH+  K Y
Sbjct: 484 EKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPY 543

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y+C  C     +  QL++H+  H G K   C +
Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K EL +H+ +  H G     Y C+ C    R K ++++H+   HT  + F C+
Sbjct: 604 CRKAFFEKSELIRHLRT--HTGEKP--YECNECRKAFREKSSLINHQRI-HTGEKPFECS 658

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       + L+ H+R   G  P
Sbjct: 659 ECGKAFSRKSHLIPHQRTHTGEKP 682



 Score =  178 bits (451), Expect = 5e-44
 Identities = 121/440 (27%), Positives = 181/440 (41%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F ++++L+ H  +H  +   +C  C K F+ KS+L TH     G K   
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L RH  ++H          Y C  CR+ FR   +L  H ++HT    
Sbjct: 377 CSDCRKAFFEKSELIRHQ-TIHTG-----EKPYECSECRKAFRERSSLINHQRTHTGEK- 429

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C Q  C  A   +   I H     G +   C    C   F+    +  H ++H
Sbjct: 430 ----PHGCIQ--CGKAFSQKSHLISHQMTHTGEKPFICS--KCGKAFSRKSQLVRHQRTH 481

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S K     H++  H G +   C+ C  A         H  + H  
Sbjct: 482 TGEKPYECSECGKAFSEKLSLTNHQRI-HTGEKPYVCSECGKAFCQKSHLISHQ-RTHTG 539

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  L  H   HTGEKP++C  C+      S L+ H   H+  K Y
Sbjct: 540 EKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ C      K  L  H+R H G+  Y+CN+C         L +H+  H G K   C  
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A    +  + H+       T    Y C  C      K  +++H+   HT  + + C 
Sbjct: 660 CGKA----FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI-HTGEKPYRCI 714

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  + FS  + L + ++ H
Sbjct: 715 ECG-KAFSQKSQLINHQRTH 733



 Score =  163 bits (412), Expect = 2e-39
 Identities = 109/422 (25%), Positives = 177/422 (41%), Gaps = 22/422 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSG-TESLFKTHMCPECKRCF 172
           G+  +E+ N+   ++  T +   +  + G+   R    V    T +  K   C +C++ F
Sbjct: 325 GRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAF 384

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L+ H  +H  +   +C  C+K F  +S L  H     GEK H C  C  +  +++
Sbjct: 385 FEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKS 444

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H       +++     + C  C + F     L  H ++HT        P  C +  
Sbjct: 445 HLISHQ------MTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEK-----PYECSE-- 491

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A  ++ +   H +   G +   C    C   F     + +H ++H     + C  C 
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEKPYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A   K     H++  H G +   C  C  A         H  ++H  EK ++C  C  A
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQ-RIHTGEKPYECSLCRKA 607

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  LIRH+  HTGEKP++C  C    R+ S L  H   H+  K + C+ECG     K
Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRK 667

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
            +L  H R H G+  Y C++C     +  QL +H+  H G K   C  C  A  +K +L 
Sbjct: 668 SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 529 KH 530
            H
Sbjct: 728 NH 729



 Score =  162 bits (411), Expect = 2e-39
 Identities = 102/353 (28%), Positives = 150/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F++R+ L+ H   H  +    C  C K F+ KS L +H +   GEK   
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH  +   +        Y C  C + F    +L  H + HT    
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGE------KPYECSECGKAFSEKLSLTNHQRIHTGEK- 513

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A   +   I H +   G +  EC    C   F    ++  H ++H
Sbjct: 514 ----PYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSE--CGKAFGEKSSLATHQRTH 565

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C+ A S K     H++  H G +   C+ C  A F       H+ + H  
Sbjct: 566 TGEKPYECRDCEKAFSQKSQLNTHQRI-HTGEKPYECSLCRKAFFEKSELIRHL-RTHTG 623

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  LI H  +HTGEKP +C  C       S+L  H  TH+  K Y
Sbjct: 624 EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPY 683

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C+EC      K  L  H R H G+  Y+C +C     +  QL +H+  H  K
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVK 736



 Score =  149 bits (376), Expect = 2e-35
 Identities = 116/441 (26%), Positives = 174/441 (39%), Gaps = 44/441 (9%)

Query: 188 DPSLQCPNCQKFFTS--KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI 245
           D  L+  +C K+  S  KS++  +    LGEK + C  C     ++ +L +H +    DI
Sbjct: 174 DTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI 233

Query: 246 --------------SNFYS--------DTYACPVCREEFRLSQALKEHLKSHTAAAAAEP 283
                         S F +          Y C  C + F     L  H ++HT       
Sbjct: 234 AFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---- 289

Query: 284 LPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA- 342
            P  C +  C  A   +   I H +   G +   C  + C   F+    +  H + H   
Sbjct: 290 -PYECGE--CGKAFSRKSHLISHWRTHTGEKPYGC--NECGRAFSEKSNLINHQRIHTGE 344

Query: 343 --FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F C  C  A S K     H +  H G++   C+ C  A F       H   +H  EK 
Sbjct: 345 KPFECRECGKAFSRKSQLVTHHRT-HTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKP 402

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C EC  A   +  LI H   HTGEKPH C  C       S+L  H +TH+  K ++C+
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           +CG     K  L  H R H G+  Y+C++C         L++H+  H G K  +C  C  
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK 522

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +K     H+ S     T    Y C  C      K ++ +H+   HT  + + C  C+
Sbjct: 523 AFCQK----SHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCE 577

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                 + L  H+R   G  P
Sbjct: 578 KAFSQKSQLNTHQRIHTGEKP 598



 Score =  114 bits (284), Expect = 1e-24
 Identities = 82/326 (25%), Positives = 124/326 (38%), Gaps = 48/326 (14%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K H C +C + F +++HL+ H   H  +    C  C K F+ KS+L  H     GEK + 
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E+ +L  H   +H          Y C  C + F     L  H ++HT    
Sbjct: 489 CSECGKAFSEKLSLTNHQR-IHTG-----EKPYVCSECGKAFCQKSHLISHQRTHTGEK- 541

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++ +   H +   G +  ECR   C   F+    +  H + H
Sbjct: 542 ----PYECSE--CGKAFGEKSSLATHQRTHTGEKPYECR--DCEKAFSQKSQLNTHQRIH 593

Query: 341 YA-------------------------------FHCPHCDFACSNKHLFRKHKKQGHPGS 369
                                            + C  C  A   K     H++  H G 
Sbjct: 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGE 652

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C+ C  A F+  ++     + H  EK + C EC  A + K  L+ H  +HTGEKP+
Sbjct: 653 KPFECSECGKA-FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPY 711

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTK 455
           +C  C       S L  H  TH+  K
Sbjct: 712 RCIECGKAFSQKSQLINHQRTHTVKK 737



 Score =  107 bits (267), Expect = 1e-22
 Identities = 99/393 (25%), Positives = 147/393 (37%), Gaps = 48/393 (12%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  ++  L  HQ        +GE    CS C       ++L  HQ+      
Sbjct: 375  FGCSDCRKAFFEKSELIRHQTI-----HTGEKPYECSECRKAFRERSSLINHQRTH---- 425

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH  C  CG    Q   +  H+ + H G KP  C  C  + +R+ +L  HQ  
Sbjct: 426  ---TGEKPH-GCIQCGKAFSQKSHLISHQ-MTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F     L  H+ R+H     + C  C  +   +  +  H  + H 
Sbjct: 481  HTGEKPYECSECGKAFSEKLSLTNHQ-RIHTGEKPYVCSECGKAFCQKSHLISHQRT-HT 538

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +++L  H  R H             T E P  C  C       +
Sbjct: 539  GEKPYECSECGKAFGEKSSLATHQ-RTH-------------TGEKPYECRDCEKAFSQKS 584

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C++AF  +  L  H R       + C  C  A RE+  L+ 
Sbjct: 585  QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644

Query: 1398 HYL----EQHEETSAAVAASDGDGD--------AGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      E+  E S    A               G+ P  C  C      +  L +H + 
Sbjct: 645  HQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI 704

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
            H G + Y+C +C  +   + ++  H R HT +K
Sbjct: 705  HTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737


>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
            [Homo sapiens]
          Length = 738

 Score =  231 bits (588), Expect = 6e-60
 Identities = 160/546 (29%), Positives = 225/546 (41%), Gaps = 53/546 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  Q+    TH         +GE   +CS C       + L  HQ+      
Sbjct: 235  FGCGNCGKTFPQKSQFITHH-----RTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---- 285

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG+CG    +   +  H R  H G KP+ C  C  + + +  L  HQ  
Sbjct: 286  ---TGEKPY-ECGECGKAFSRKSHLISHWRT-HTGEKPYGCNECGRAFSEKSNLINHQRI 340

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L  H  R H  T    C  C  + + + ++ RH  + H 
Sbjct: 341  HTGEKPFECRECGKAFSRKSQLVTHH-RTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHT 398

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F   ++L  H  R H             T E P  C +CG      +
Sbjct: 399  GEKPYECSECRKAFRERSSLINHQ-RTH-------------TGEKPHGCIQCGKAFSQKS 444

Query: 1342 SLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H  T        C  C +AF  +  L  H+R       + C  C  A  E++ L  
Sbjct: 445  HLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTN 504

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C      +  L  H + H G + Y+C++C
Sbjct: 505  H---QRIHT-------------GEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              +   +  +  H R HTGEKPY C  C  A +  S+L  H RIH  E+ Y C  C    
Sbjct: 549  GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
               ++L  H+  HTG KPY+C EC        +L  HQ   H   + F C +CGKAF  +
Sbjct: 609  FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGEKPFECSECGKAFSRK 667

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  H R H+  KPY C+ C +AF   + L +H   HT   P+ C  C     QK Q++
Sbjct: 668  SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 1638 KHVRRH 1643
             H R H
Sbjct: 728  NHQRTH 733



 Score =  203 bits (516), Expect = 1e-51
 Identities = 137/467 (29%), Positives = 194/467 (41%), Gaps = 39/467 (8%)

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
            K+S+ +  HR     G K ++C  C    +++  L  HQSRH       C +C +TF   
Sbjct: 190  KKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQK 247

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S+   H  R H     + C  C  +   +  +T H  + H G   + C +C   FS ++ 
Sbjct: 248  SQFITHH-RTHTGEKPYNCSQCGKAFSQKSQLTSHQRT-HTGEKPYECGECGKAFSRKSH 305

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
            L  H  R H             T E P  C+ CG      ++L  H R        EC  
Sbjct: 306  LISH-WRTH-------------TGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351

Query: 1359 CQEAFPSRLALDEHRRQQHFSHR--CQLCDFAARERVGLVKHYLEQHEETSAAVAASDGD 1416
            C +AF  +  L  H R    +    C  C  A  E+  L++H                  
Sbjct: 352  CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH-------------- 397

Query: 1417 GDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTG 1476
               G+ P  C  C    R +  L +H + H G + + C  C  +   +  +  H   HTG
Sbjct: 398  --TGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG 455

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            EKP+ C  C  A +  S+L  H R H  E+ Y C ECG        L  H   HTG KPY
Sbjct: 456  EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPY 515

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
             C EC     +   L  HQ T H   + + C +CGKAF  +  L TH R H+  KPY C 
Sbjct: 516  VCSECGKAFCQKSHLISHQRT-HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECR 574

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             C +AF   + L  H   HT   P+ C LC     +K ++++H+R H
Sbjct: 575  DCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTH 621



 Score =  190 bits (482), Expect = 1e-47
 Identities = 130/444 (29%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F K+  L++H   H  D +  C NC K F  KS+  TH     GEK ++
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYN 264

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L  H        ++     Y C  C + F     L  H ++HT    
Sbjct: 265 CSQCGKAFSQKSQLTSHQR------THTGEKPYECGECGKAFSRKSHLISHWRTHTGEK- 317

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++   I H +   G +  ECR   C   F+    +  HH++H
Sbjct: 318 ----PYGCNE--CGRAFSEKSNLINHQRIHTGEKPFECR--ECGKAFSRKSQLVTHHRTH 369

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  A   K    +H+   H G +   C+ C  A     +  +H  + H  
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTI-HTGEKPYECSECRKAFRERSSLINH-QRTHTG 427

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK H C +C  A + K  LI H + HTGEKP  C  C       S L +H  TH+  K Y
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y C++C     +   L SH+  H G K   C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K  L  H  +  H G     Y C  C      K  + +H+   HT  + + C+
Sbjct: 548 CGKAFGEKSSLATHQRT--HTGEKP--YECRDCEKAFSQKSQLNTHQRI-HTGEKPYECS 602

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           LC    F  + L+ H R   G  P
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKP 626



 Score =  180 bits (457), Expect = 9e-45
 Identities = 126/444 (28%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +++ L  H   H  +   +C  C K F+ KS L +H     GEK + 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L  H   +H     F      C  C + F     L  H ++HT    
Sbjct: 321 CNECGRAFSEKSNLINHQR-IHTGEKPF-----ECRECGKAFSRKSQLVTHHRTHTGTK- 373

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A  ++   I+H     G +  EC    C   F    ++  H ++H
Sbjct: 374 ----PFGC--SDCRKAFFEKSELIRHQTIHTGEKPYECSE--CRKAFRERSSLINHQRTH 425

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                  C  C  A S K     H+   H G +   C+ C  A         H  + H  
Sbjct: 426 TGEKPHGCIQCGKAFSQKSHLISHQMT-HTGEKPFICSKCGKAFSRKSQLVRHQ-RTHTG 483

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A + K  L  H  +HTGEKP+ C  C       S+L  H  TH+  K Y
Sbjct: 484 EKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPY 543

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y+C  C     +  QL++H+  H G K   C +
Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K EL +H+ +  H G     Y C+ C    R K ++++H+   HT  + F C+
Sbjct: 604 CRKAFFEKSELIRHLRT--HTGEKP--YECNECRKAFREKSSLINHQRI-HTGEKPFECS 658

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       + L+ H+R   G  P
Sbjct: 659 ECGKAFSRKSHLIPHQRTHTGEKP 682



 Score =  178 bits (451), Expect = 5e-44
 Identities = 121/440 (27%), Positives = 181/440 (41%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F ++++L+ H  +H  +   +C  C K F+ KS+L TH     G K   
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L RH  ++H          Y C  CR+ FR   +L  H ++HT    
Sbjct: 377 CSDCRKAFFEKSELIRHQ-TIHTG-----EKPYECSECRKAFRERSSLINHQRTHTGEK- 429

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C Q  C  A   +   I H     G +   C    C   F+    +  H ++H
Sbjct: 430 ----PHGCIQ--CGKAFSQKSHLISHQMTHTGEKPFICS--KCGKAFSRKSQLVRHQRTH 481

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S K     H++  H G +   C+ C  A         H  + H  
Sbjct: 482 TGEKPYECSECGKAFSEKLSLTNHQRI-HTGEKPYVCSECGKAFCQKSHLISHQ-RTHTG 539

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  L  H   HTGEKP++C  C+      S L+ H   H+  K Y
Sbjct: 540 EKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ C      K  L  H+R H G+  Y+CN+C         L +H+  H G K   C  
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A    +  + H+       T    Y C  C      K  +++H+   HT  + + C 
Sbjct: 660 CGKA----FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI-HTGEKPYRCI 714

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  + FS  + L + ++ H
Sbjct: 715 ECG-KAFSQKSQLINHQRTH 733



 Score =  163 bits (412), Expect = 2e-39
 Identities = 109/422 (25%), Positives = 177/422 (41%), Gaps = 22/422 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSG-TESLFKTHMCPECKRCF 172
           G+  +E+ N+   ++  T +   +  + G+   R    V    T +  K   C +C++ F
Sbjct: 325 GRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAF 384

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L+ H  +H  +   +C  C+K F  +S L  H     GEK H C  C  +  +++
Sbjct: 385 FEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKS 444

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H       +++     + C  C + F     L  H ++HT        P  C +  
Sbjct: 445 HLISHQ------MTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEK-----PYECSE-- 491

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A  ++ +   H +   G +   C    C   F     + +H ++H     + C  C 
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEKPYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A   K     H++  H G +   C  C  A         H  ++H  EK ++C  C  A
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQ-RIHTGEKPYECSLCRKA 607

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  LIRH+  HTGEKP++C  C    R+ S L  H   H+  K + C+ECG     K
Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRK 667

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
            +L  H R H G+  Y C++C     +  QL +H+  H G K   C  C  A  +K +L 
Sbjct: 668 SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 529 KH 530
            H
Sbjct: 728 NH 729



 Score =  162 bits (411), Expect = 2e-39
 Identities = 102/353 (28%), Positives = 150/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F++R+ L+ H   H  +    C  C K F+ KS L +H +   GEK   
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH  +   +        Y C  C + F    +L  H + HT    
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGE------KPYECSECGKAFSEKLSLTNHQRIHTGEK- 513

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A   +   I H +   G +  EC    C   F    ++  H ++H
Sbjct: 514 ----PYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSE--CGKAFGEKSSLATHQRTH 565

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C+ A S K     H++  H G +   C+ C  A F       H+ + H  
Sbjct: 566 TGEKPYECRDCEKAFSQKSQLNTHQRI-HTGEKPYECSLCRKAFFEKSELIRHL-RTHTG 623

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  LI H  +HTGEKP +C  C       S+L  H  TH+  K Y
Sbjct: 624 EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPY 683

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C+EC      K  L  H R H G+  Y+C +C     +  QL +H+  H  K
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVK 736



 Score =  149 bits (376), Expect = 2e-35
 Identities = 116/441 (26%), Positives = 174/441 (39%), Gaps = 44/441 (9%)

Query: 188 DPSLQCPNCQKFFTS--KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI 245
           D  L+  +C K+  S  KS++  +    LGEK + C  C     ++ +L +H +    DI
Sbjct: 174 DTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI 233

Query: 246 --------------SNFYS--------DTYACPVCREEFRLSQALKEHLKSHTAAAAAEP 283
                         S F +          Y C  C + F     L  H ++HT       
Sbjct: 234 AFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---- 289

Query: 284 LPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA- 342
            P  C +  C  A   +   I H +   G +   C  + C   F+    +  H + H   
Sbjct: 290 -PYECGE--CGKAFSRKSHLISHWRTHTGEKPYGC--NECGRAFSEKSNLINHQRIHTGE 344

Query: 343 --FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F C  C  A S K     H +  H G++   C+ C  A F       H   +H  EK 
Sbjct: 345 KPFECRECGKAFSRKSQLVTHHRT-HTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKP 402

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C EC  A   +  LI H   HTGEKPH C  C       S+L  H +TH+  K ++C+
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           +CG     K  L  H R H G+  Y+C++C         L++H+  H G K  +C  C  
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK 522

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +K     H+ S     T    Y C  C      K ++ +H+   HT  + + C  C+
Sbjct: 523 AFCQK----SHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCE 577

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                 + L  H+R   G  P
Sbjct: 578 KAFSQKSQLNTHQRIHTGEKP 598



 Score =  114 bits (284), Expect = 1e-24
 Identities = 82/326 (25%), Positives = 124/326 (38%), Gaps = 48/326 (14%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K H C +C + F +++HL+ H   H  +    C  C K F+ KS+L  H     GEK + 
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E+ +L  H   +H          Y C  C + F     L  H ++HT    
Sbjct: 489 CSECGKAFSEKLSLTNHQR-IHTG-----EKPYVCSECGKAFCQKSHLISHQRTHTGEK- 541

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++ +   H +   G +  ECR   C   F+    +  H + H
Sbjct: 542 ----PYECSE--CGKAFGEKSSLATHQRTHTGEKPYECR--DCEKAFSQKSQLNTHQRIH 593

Query: 341 YA-------------------------------FHCPHCDFACSNKHLFRKHKKQGHPGS 369
                                            + C  C  A   K     H++  H G 
Sbjct: 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGE 652

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C+ C  A F+  ++     + H  EK + C EC  A + K  L+ H  +HTGEKP+
Sbjct: 653 KPFECSECGKA-FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPY 711

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTK 455
           +C  C       S L  H  TH+  K
Sbjct: 712 RCIECGKAFSQKSQLINHQRTHTVKK 737



 Score =  107 bits (267), Expect = 1e-22
 Identities = 99/393 (25%), Positives = 147/393 (37%), Gaps = 48/393 (12%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  ++  L  HQ        +GE    CS C       ++L  HQ+      
Sbjct: 375  FGCSDCRKAFFEKSELIRHQTI-----HTGEKPYECSECRKAFRERSSLINHQRTH---- 425

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH  C  CG    Q   +  H+ + H G KP  C  C  + +R+ +L  HQ  
Sbjct: 426  ---TGEKPH-GCIQCGKAFSQKSHLISHQ-MTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F     L  H+ R+H     + C  C  +   +  +  H  + H 
Sbjct: 481  HTGEKPYECSECGKAFSEKLSLTNHQ-RIHTGEKPYVCSECGKAFCQKSHLISHQRT-HT 538

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +++L  H  R H             T E P  C  C       +
Sbjct: 539  GEKPYECSECGKAFGEKSSLATHQ-RTH-------------TGEKPYECRDCEKAFSQKS 584

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C++AF  +  L  H R       + C  C  A RE+  L+ 
Sbjct: 585  QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644

Query: 1398 HYL----EQHEETSAAVAASDGDGD--------AGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      E+  E S    A               G+ P  C  C      +  L +H + 
Sbjct: 645  HQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI 704

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
            H G + Y+C +C  +   + ++  H R HT +K
Sbjct: 705  HTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737


>gi|188497655 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  231 bits (588), Expect = 6e-60
 Identities = 160/546 (29%), Positives = 225/546 (41%), Gaps = 53/546 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  Q+    TH         +GE   +CS C       + L  HQ+      
Sbjct: 235  FGCGNCGKTFPQKSQFITHH-----RTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---- 285

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG+CG    +   +  H R  H G KP+ C  C  + + +  L  HQ  
Sbjct: 286  ---TGEKPY-ECGECGKAFSRKSHLISHWRT-HTGEKPYGCNECGRAFSEKSNLINHQRI 340

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L  H  R H  T    C  C  + + + ++ RH  + H 
Sbjct: 341  HTGEKPFECRECGKAFSRKSQLVTHH-RTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHT 398

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F   ++L  H  R H             T E P  C +CG      +
Sbjct: 399  GEKPYECSECRKAFRERSSLINHQ-RTH-------------TGEKPHGCIQCGKAFSQKS 444

Query: 1342 SLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H  T        C  C +AF  +  L  H+R       + C  C  A  E++ L  
Sbjct: 445  HLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTN 504

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C      +  L  H + H G + Y+C++C
Sbjct: 505  H---QRIHT-------------GEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              +   +  +  H R HTGEKPY C  C  A +  S+L  H RIH  E+ Y C  C    
Sbjct: 549  GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
               ++L  H+  HTG KPY+C EC        +L  HQ   H   + F C +CGKAF  +
Sbjct: 609  FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGEKPFECSECGKAFSRK 667

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  H R H+  KPY C+ C +AF   + L +H   HT   P+ C  C     QK Q++
Sbjct: 668  SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 1638 KHVRRH 1643
             H R H
Sbjct: 728  NHQRTH 733



 Score =  203 bits (516), Expect = 1e-51
 Identities = 137/467 (29%), Positives = 194/467 (41%), Gaps = 39/467 (8%)

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
            K+S+ +  HR     G K ++C  C    +++  L  HQSRH       C +C +TF   
Sbjct: 190  KKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQK 247

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S+   H  R H     + C  C  +   +  +T H  + H G   + C +C   FS ++ 
Sbjct: 248  SQFITHH-RTHTGEKPYNCSQCGKAFSQKSQLTSHQRT-HTGEKPYECGECGKAFSRKSH 305

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
            L  H  R H             T E P  C+ CG      ++L  H R        EC  
Sbjct: 306  LISH-WRTH-------------TGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351

Query: 1359 CQEAFPSRLALDEHRRQQHFSHR--CQLCDFAARERVGLVKHYLEQHEETSAAVAASDGD 1416
            C +AF  +  L  H R    +    C  C  A  E+  L++H                  
Sbjct: 352  CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH-------------- 397

Query: 1417 GDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTG 1476
               G+ P  C  C    R +  L +H + H G + + C  C  +   +  +  H   HTG
Sbjct: 398  --TGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG 455

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            EKP+ C  C  A +  S+L  H R H  E+ Y C ECG        L  H   HTG KPY
Sbjct: 456  EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPY 515

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
             C EC     +   L  HQ T H   + + C +CGKAF  +  L TH R H+  KPY C 
Sbjct: 516  VCSECGKAFCQKSHLISHQRT-HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECR 574

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             C +AF   + L  H   HT   P+ C LC     +K ++++H+R H
Sbjct: 575  DCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTH 621



 Score =  190 bits (482), Expect = 1e-47
 Identities = 130/444 (29%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F K+  L++H   H  D +  C NC K F  KS+  TH     GEK ++
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYN 264

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L  H        ++     Y C  C + F     L  H ++HT    
Sbjct: 265 CSQCGKAFSQKSQLTSHQR------THTGEKPYECGECGKAFSRKSHLISHWRTHTGEK- 317

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++   I H +   G +  ECR   C   F+    +  HH++H
Sbjct: 318 ----PYGCNE--CGRAFSEKSNLINHQRIHTGEKPFECR--ECGKAFSRKSQLVTHHRTH 369

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  A   K    +H+   H G +   C+ C  A     +  +H  + H  
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTI-HTGEKPYECSECRKAFRERSSLINH-QRTHTG 427

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK H C +C  A + K  LI H + HTGEKP  C  C       S L +H  TH+  K Y
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y C++C     +   L SH+  H G K   C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K  L  H  +  H G     Y C  C      K  + +H+   HT  + + C+
Sbjct: 548 CGKAFGEKSSLATHQRT--HTGEKP--YECRDCEKAFSQKSQLNTHQRI-HTGEKPYECS 602

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           LC    F  + L+ H R   G  P
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKP 626



 Score =  180 bits (457), Expect = 9e-45
 Identities = 126/444 (28%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +++ L  H   H  +   +C  C K F+ KS L +H     GEK + 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L  H   +H     F      C  C + F     L  H ++HT    
Sbjct: 321 CNECGRAFSEKSNLINHQR-IHTGEKPF-----ECRECGKAFSRKSQLVTHHRTHTGTK- 373

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A  ++   I+H     G +  EC    C   F    ++  H ++H
Sbjct: 374 ----PFGC--SDCRKAFFEKSELIRHQTIHTGEKPYECSE--CRKAFRERSSLINHQRTH 425

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                  C  C  A S K     H+   H G +   C+ C  A         H  + H  
Sbjct: 426 TGEKPHGCIQCGKAFSQKSHLISHQMT-HTGEKPFICSKCGKAFSRKSQLVRHQ-RTHTG 483

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A + K  L  H  +HTGEKP+ C  C       S+L  H  TH+  K Y
Sbjct: 484 EKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPY 543

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y+C  C     +  QL++H+  H G K   C +
Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K EL +H+ +  H G     Y C+ C    R K ++++H+   HT  + F C+
Sbjct: 604 CRKAFFEKSELIRHLRT--HTGEKP--YECNECRKAFREKSSLINHQRI-HTGEKPFECS 658

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       + L+ H+R   G  P
Sbjct: 659 ECGKAFSRKSHLIPHQRTHTGEKP 682



 Score =  178 bits (451), Expect = 5e-44
 Identities = 121/440 (27%), Positives = 181/440 (41%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F ++++L+ H  +H  +   +C  C K F+ KS+L TH     G K   
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L RH  ++H          Y C  CR+ FR   +L  H ++HT    
Sbjct: 377 CSDCRKAFFEKSELIRHQ-TIHTG-----EKPYECSECRKAFRERSSLINHQRTHTGEK- 429

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C Q  C  A   +   I H     G +   C    C   F+    +  H ++H
Sbjct: 430 ----PHGCIQ--CGKAFSQKSHLISHQMTHTGEKPFICS--KCGKAFSRKSQLVRHQRTH 481

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S K     H++  H G +   C+ C  A         H  + H  
Sbjct: 482 TGEKPYECSECGKAFSEKLSLTNHQRI-HTGEKPYVCSECGKAFCQKSHLISHQ-RTHTG 539

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  L  H   HTGEKP++C  C+      S L+ H   H+  K Y
Sbjct: 540 EKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ C      K  L  H+R H G+  Y+CN+C         L +H+  H G K   C  
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A    +  + H+       T    Y C  C      K  +++H+   HT  + + C 
Sbjct: 660 CGKA----FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI-HTGEKPYRCI 714

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  + FS  + L + ++ H
Sbjct: 715 ECG-KAFSQKSQLINHQRTH 733



 Score =  163 bits (412), Expect = 2e-39
 Identities = 109/422 (25%), Positives = 177/422 (41%), Gaps = 22/422 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSG-TESLFKTHMCPECKRCF 172
           G+  +E+ N+   ++  T +   +  + G+   R    V    T +  K   C +C++ F
Sbjct: 325 GRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAF 384

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L+ H  +H  +   +C  C+K F  +S L  H     GEK H C  C  +  +++
Sbjct: 385 FEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKS 444

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H       +++     + C  C + F     L  H ++HT        P  C +  
Sbjct: 445 HLISHQ------MTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEK-----PYECSE-- 491

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A  ++ +   H +   G +   C    C   F     + +H ++H     + C  C 
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEKPYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A   K     H++  H G +   C  C  A         H  ++H  EK ++C  C  A
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQ-RIHTGEKPYECSLCRKA 607

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  LIRH+  HTGEKP++C  C    R+ S L  H   H+  K + C+ECG     K
Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRK 667

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
            +L  H R H G+  Y C++C     +  QL +H+  H G K   C  C  A  +K +L 
Sbjct: 668 SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 529 KH 530
            H
Sbjct: 728 NH 729



 Score =  162 bits (411), Expect = 2e-39
 Identities = 102/353 (28%), Positives = 150/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F++R+ L+ H   H  +    C  C K F+ KS L +H +   GEK   
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH  +   +        Y C  C + F    +L  H + HT    
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGE------KPYECSECGKAFSEKLSLTNHQRIHTGEK- 513

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A   +   I H +   G +  EC    C   F    ++  H ++H
Sbjct: 514 ----PYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSE--CGKAFGEKSSLATHQRTH 565

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C+ A S K     H++  H G +   C+ C  A F       H+ + H  
Sbjct: 566 TGEKPYECRDCEKAFSQKSQLNTHQRI-HTGEKPYECSLCRKAFFEKSELIRHL-RTHTG 623

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  LI H  +HTGEKP +C  C       S+L  H  TH+  K Y
Sbjct: 624 EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPY 683

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C+EC      K  L  H R H G+  Y+C +C     +  QL +H+  H  K
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVK 736



 Score =  149 bits (376), Expect = 2e-35
 Identities = 116/441 (26%), Positives = 174/441 (39%), Gaps = 44/441 (9%)

Query: 188 DPSLQCPNCQKFFTS--KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI 245
           D  L+  +C K+  S  KS++  +    LGEK + C  C     ++ +L +H +    DI
Sbjct: 174 DTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI 233

Query: 246 --------------SNFYS--------DTYACPVCREEFRLSQALKEHLKSHTAAAAAEP 283
                         S F +          Y C  C + F     L  H ++HT       
Sbjct: 234 AFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---- 289

Query: 284 LPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA- 342
            P  C +  C  A   +   I H +   G +   C  + C   F+    +  H + H   
Sbjct: 290 -PYECGE--CGKAFSRKSHLISHWRTHTGEKPYGC--NECGRAFSEKSNLINHQRIHTGE 344

Query: 343 --FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F C  C  A S K     H +  H G++   C+ C  A F       H   +H  EK 
Sbjct: 345 KPFECRECGKAFSRKSQLVTHHRT-HTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKP 402

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C EC  A   +  LI H   HTGEKPH C  C       S+L  H +TH+  K ++C+
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           +CG     K  L  H R H G+  Y+C++C         L++H+  H G K  +C  C  
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK 522

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +K     H+ S     T    Y C  C      K ++ +H+   HT  + + C  C+
Sbjct: 523 AFCQK----SHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCE 577

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                 + L  H+R   G  P
Sbjct: 578 KAFSQKSQLNTHQRIHTGEKP 598



 Score =  114 bits (284), Expect = 1e-24
 Identities = 82/326 (25%), Positives = 124/326 (38%), Gaps = 48/326 (14%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K H C +C + F +++HL+ H   H  +    C  C K F+ KS+L  H     GEK + 
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E+ +L  H   +H          Y C  C + F     L  H ++HT    
Sbjct: 489 CSECGKAFSEKLSLTNHQR-IHTG-----EKPYVCSECGKAFCQKSHLISHQRTHTGEK- 541

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++ +   H +   G +  ECR   C   F+    +  H + H
Sbjct: 542 ----PYECSE--CGKAFGEKSSLATHQRTHTGEKPYECR--DCEKAFSQKSQLNTHQRIH 593

Query: 341 YA-------------------------------FHCPHCDFACSNKHLFRKHKKQGHPGS 369
                                            + C  C  A   K     H++  H G 
Sbjct: 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGE 652

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C+ C  A F+  ++     + H  EK + C EC  A + K  L+ H  +HTGEKP+
Sbjct: 653 KPFECSECGKA-FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPY 711

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTK 455
           +C  C       S L  H  TH+  K
Sbjct: 712 RCIECGKAFSQKSQLINHQRTHTVKK 737



 Score =  107 bits (267), Expect = 1e-22
 Identities = 99/393 (25%), Positives = 147/393 (37%), Gaps = 48/393 (12%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  ++  L  HQ        +GE    CS C       ++L  HQ+      
Sbjct: 375  FGCSDCRKAFFEKSELIRHQTI-----HTGEKPYECSECRKAFRERSSLINHQRTH---- 425

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH  C  CG    Q   +  H+ + H G KP  C  C  + +R+ +L  HQ  
Sbjct: 426  ---TGEKPH-GCIQCGKAFSQKSHLISHQ-MTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F     L  H+ R+H     + C  C  +   +  +  H  + H 
Sbjct: 481  HTGEKPYECSECGKAFSEKLSLTNHQ-RIHTGEKPYVCSECGKAFCQKSHLISHQRT-HT 538

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +++L  H  R H             T E P  C  C       +
Sbjct: 539  GEKPYECSECGKAFGEKSSLATHQ-RTH-------------TGEKPYECRDCEKAFSQKS 584

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C++AF  +  L  H R       + C  C  A RE+  L+ 
Sbjct: 585  QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644

Query: 1398 HYL----EQHEETSAAVAASDGDGD--------AGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      E+  E S    A               G+ P  C  C      +  L +H + 
Sbjct: 645  HQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI 704

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
            H G + Y+C +C  +   + ++  H R HT +K
Sbjct: 705  HTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737


>gi|188497653 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  231 bits (588), Expect = 6e-60
 Identities = 160/546 (29%), Positives = 225/546 (41%), Gaps = 53/546 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  Q+    TH         +GE   +CS C       + L  HQ+      
Sbjct: 235  FGCGNCGKTFPQKSQFITHH-----RTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---- 285

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG+CG    +   +  H R  H G KP+ C  C  + + +  L  HQ  
Sbjct: 286  ---TGEKPY-ECGECGKAFSRKSHLISHWRT-HTGEKPYGCNECGRAFSEKSNLINHQRI 340

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   S+L  H  R H  T    C  C  + + + ++ RH  + H 
Sbjct: 341  HTGEKPFECRECGKAFSRKSQLVTHH-RTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHT 398

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F   ++L  H  R H             T E P  C +CG      +
Sbjct: 399  GEKPYECSECRKAFRERSSLINHQ-RTH-------------TGEKPHGCIQCGKAFSQKS 444

Query: 1342 SLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H  T        C  C +AF  +  L  H+R       + C  C  A  E++ L  
Sbjct: 445  HLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTN 504

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C      +  L  H + H G + Y+C++C
Sbjct: 505  H---QRIHT-------------GEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              +   +  +  H R HTGEKPY C  C  A +  S+L  H RIH  E+ Y C  C    
Sbjct: 549  GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
               ++L  H+  HTG KPY+C EC        +L  HQ   H   + F C +CGKAF  +
Sbjct: 609  FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGEKPFECSECGKAFSRK 667

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  H R H+  KPY C+ C +AF   + L +H   HT   P+ C  C     QK Q++
Sbjct: 668  SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 1638 KHVRRH 1643
             H R H
Sbjct: 728  NHQRTH 733



 Score =  203 bits (516), Expect = 1e-51
 Identities = 137/467 (29%), Positives = 194/467 (41%), Gaps = 39/467 (8%)

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
            K+S+ +  HR     G K ++C  C    +++  L  HQSRH       C +C +TF   
Sbjct: 190  KKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQK 247

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S+   H  R H     + C  C  +   +  +T H  + H G   + C +C   FS ++ 
Sbjct: 248  SQFITHH-RTHTGEKPYNCSQCGKAFSQKSQLTSHQRT-HTGEKPYECGECGKAFSRKSH 305

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
            L  H  R H             T E P  C+ CG      ++L  H R        EC  
Sbjct: 306  LISH-WRTH-------------TGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351

Query: 1359 CQEAFPSRLALDEHRRQQHFSHR--CQLCDFAARERVGLVKHYLEQHEETSAAVAASDGD 1416
            C +AF  +  L  H R    +    C  C  A  E+  L++H                  
Sbjct: 352  CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH-------------- 397

Query: 1417 GDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTG 1476
               G+ P  C  C    R +  L +H + H G + + C  C  +   +  +  H   HTG
Sbjct: 398  --TGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG 455

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            EKP+ C  C  A +  S+L  H R H  E+ Y C ECG        L  H   HTG KPY
Sbjct: 456  EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPY 515

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
             C EC     +   L  HQ T H   + + C +CGKAF  +  L TH R H+  KPY C 
Sbjct: 516  VCSECGKAFCQKSHLISHQRT-HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECR 574

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             C +AF   + L  H   HT   P+ C LC     +K ++++H+R H
Sbjct: 575  DCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTH 621



 Score =  190 bits (482), Expect = 1e-47
 Identities = 130/444 (29%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F K+  L++H   H  D +  C NC K F  KS+  TH     GEK ++
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYN 264

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L  H        ++     Y C  C + F     L  H ++HT    
Sbjct: 265 CSQCGKAFSQKSQLTSHQR------THTGEKPYECGECGKAFSRKSHLISHWRTHTGEK- 317

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++   I H +   G +  ECR   C   F+    +  HH++H
Sbjct: 318 ----PYGCNE--CGRAFSEKSNLINHQRIHTGEKPFECR--ECGKAFSRKSQLVTHHRTH 369

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  A   K    +H+   H G +   C+ C  A     +  +H  + H  
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTI-HTGEKPYECSECRKAFRERSSLINH-QRTHTG 427

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK H C +C  A + K  LI H + HTGEKP  C  C       S L +H  TH+  K Y
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y C++C     +   L SH+  H G K   C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K  L  H  +  H G     Y C  C      K  + +H+   HT  + + C+
Sbjct: 548 CGKAFGEKSSLATHQRT--HTGEKP--YECRDCEKAFSQKSQLNTHQRI-HTGEKPYECS 602

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           LC    F  + L+ H R   G  P
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKP 626



 Score =  180 bits (457), Expect = 9e-45
 Identities = 126/444 (28%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +++ L  H   H  +   +C  C K F+ KS L +H     GEK + 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L  H   +H     F      C  C + F     L  H ++HT    
Sbjct: 321 CNECGRAFSEKSNLINHQR-IHTGEKPF-----ECRECGKAFSRKSQLVTHHRTHTGTK- 373

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A  ++   I+H     G +  EC    C   F    ++  H ++H
Sbjct: 374 ----PFGC--SDCRKAFFEKSELIRHQTIHTGEKPYECSE--CRKAFRERSSLINHQRTH 425

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                  C  C  A S K     H+   H G +   C+ C  A         H  + H  
Sbjct: 426 TGEKPHGCIQCGKAFSQKSHLISHQMT-HTGEKPFICSKCGKAFSRKSQLVRHQ-RTHTG 483

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A + K  L  H  +HTGEKP+ C  C       S+L  H  TH+  K Y
Sbjct: 484 EKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPY 543

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ECG     K  L  H R H G+  Y+C  C     +  QL++H+  H G K   C +
Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A   K EL +H+ +  H G     Y C+ C    R K ++++H+   HT  + F C+
Sbjct: 604 CRKAFFEKSELIRHLRT--HTGEKP--YECNECRKAFREKSSLINHQRI-HTGEKPFECS 658

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       + L+ H+R   G  P
Sbjct: 659 ECGKAFSRKSHLIPHQRTHTGEKP 682



 Score =  178 bits (451), Expect = 5e-44
 Identities = 121/440 (27%), Positives = 181/440 (41%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC R F ++++L+ H  +H  +   +C  C K F+ KS+L TH     G K   
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E++ L RH  ++H          Y C  CR+ FR   +L  H ++HT    
Sbjct: 377 CSDCRKAFFEKSELIRHQ-TIHTG-----EKPYECSECRKAFRERSSLINHQRTHTGEK- 429

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C Q  C  A   +   I H     G +   C    C   F+    +  H ++H
Sbjct: 430 ----PHGCIQ--CGKAFSQKSHLISHQMTHTGEKPFICS--KCGKAFSRKSQLVRHQRTH 481

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S K     H++  H G +   C+ C  A         H  + H  
Sbjct: 482 TGEKPYECSECGKAFSEKLSLTNHQRI-HTGEKPYVCSECGKAFCQKSHLISHQ-RTHTG 539

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  L  H   HTGEKP++C  C+      S L+ H   H+  K Y
Sbjct: 540 EKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+ C      K  L  H+R H G+  Y+CN+C         L +H+  H G K   C  
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A    +  + H+       T    Y C  C      K  +++H+   HT  + + C 
Sbjct: 660 CGKA----FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI-HTGEKPYRCI 714

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  + FS  + L + ++ H
Sbjct: 715 ECG-KAFSQKSQLINHQRTH 733



 Score =  163 bits (412), Expect = 2e-39
 Identities = 109/422 (25%), Positives = 177/422 (41%), Gaps = 22/422 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSG-TESLFKTHMCPECKRCF 172
           G+  +E+ N+   ++  T +   +  + G+   R    V    T +  K   C +C++ F
Sbjct: 325 GRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAF 384

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L+ H  +H  +   +C  C+K F  +S L  H     GEK H C  C  +  +++
Sbjct: 385 FEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKS 444

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H       +++     + C  C + F     L  H ++HT        P  C +  
Sbjct: 445 HLISHQ------MTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEK-----PYECSE-- 491

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A  ++ +   H +   G +   C    C   F     + +H ++H     + C  C 
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEKPYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A   K     H++  H G +   C  C  A         H  ++H  EK ++C  C  A
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQ-RIHTGEKPYECSLCRKA 607

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  LIRH+  HTGEKP++C  C    R+ S L  H   H+  K + C+ECG     K
Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRK 667

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
            +L  H R H G+  Y C++C     +  QL +H+  H G K   C  C  A  +K +L 
Sbjct: 668 SHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLI 727

Query: 529 KH 530
            H
Sbjct: 728 NH 729



 Score =  162 bits (411), Expect = 2e-39
 Identities = 102/353 (28%), Positives = 150/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC++ F++R+ L+ H   H  +    C  C K F+ KS L +H +   GEK   
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH  +   +        Y C  C + F    +L  H + HT    
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGE------KPYECSECGKAFSEKLSLTNHQRIHTGEK- 513

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A   +   I H +   G +  EC    C   F    ++  H ++H
Sbjct: 514 ----PYVCSE--CGKAFCQKSHLISHQRTHTGEKPYECSE--CGKAFGEKSSLATHQRTH 565

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C+ A S K     H++  H G +   C+ C  A F       H+ + H  
Sbjct: 566 TGEKPYECRDCEKAFSQKSQLNTHQRI-HTGEKPYECSLCRKAFFEKSELIRHL-RTHTG 623

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A   K  LI H  +HTGEKP +C  C       S+L  H  TH+  K Y
Sbjct: 624 EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPY 683

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C+EC      K  L  H R H G+  Y+C +C     +  QL +H+  H  K
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVK 736



 Score =  149 bits (376), Expect = 2e-35
 Identities = 116/441 (26%), Positives = 174/441 (39%), Gaps = 44/441 (9%)

Query: 188 DPSLQCPNCQKFFTS--KSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI 245
           D  L+  +C K+  S  KS++  +    LGEK + C  C     ++ +L +H +    DI
Sbjct: 174 DTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI 233

Query: 246 --------------SNFYS--------DTYACPVCREEFRLSQALKEHLKSHTAAAAAEP 283
                         S F +          Y C  C + F     L  H ++HT       
Sbjct: 234 AFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---- 289

Query: 284 LPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA- 342
            P  C +  C  A   +   I H +   G +   C  + C   F+    +  H + H   
Sbjct: 290 -PYECGE--CGKAFSRKSHLISHWRTHTGEKPYGC--NECGRAFSEKSNLINHQRIHTGE 344

Query: 343 --FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F C  C  A S K     H +  H G++   C+ C  A F       H   +H  EK 
Sbjct: 345 KPFECRECGKAFSRKSQLVTHHRT-HTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKP 402

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C EC  A   +  LI H   HTGEKPH C  C       S+L  H +TH+  K ++C+
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           +CG     K  L  H R H G+  Y+C++C         L++H+  H G K  +C  C  
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK 522

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +K     H+ S     T    Y C  C      K ++ +H+   HT  + + C  C+
Sbjct: 523 AFCQK----SHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCE 577

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                 + L  H+R   G  P
Sbjct: 578 KAFSQKSQLNTHQRIHTGEKP 598



 Score =  114 bits (284), Expect = 1e-24
 Identities = 82/326 (25%), Positives = 124/326 (38%), Gaps = 48/326 (14%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K H C +C + F +++HL+ H   H  +    C  C K F+ KS+L  H     GEK + 
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  E+ +L  H   +H          Y C  C + F     L  H ++HT    
Sbjct: 489 CSECGKAFSEKLSLTNHQR-IHTG-----EKPYVCSECGKAFCQKSHLISHQRTHTGEK- 541

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A  ++ +   H +   G +  ECR   C   F+    +  H + H
Sbjct: 542 ----PYECSE--CGKAFGEKSSLATHQRTHTGEKPYECR--DCEKAFSQKSQLNTHQRIH 593

Query: 341 YA-------------------------------FHCPHCDFACSNKHLFRKHKKQGHPGS 369
                                            + C  C  A   K     H++  H G 
Sbjct: 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRI-HTGE 652

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +   C+ C  A F+  ++     + H  EK + C EC  A + K  L+ H  +HTGEKP+
Sbjct: 653 KPFECSECGKA-FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPY 711

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTK 455
           +C  C       S L  H  TH+  K
Sbjct: 712 RCIECGKAFSQKSQLINHQRTHTVKK 737



 Score =  107 bits (267), Expect = 1e-22
 Identities = 99/393 (25%), Positives = 147/393 (37%), Gaps = 48/393 (12%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +  ++  L  HQ        +GE    CS C       ++L  HQ+      
Sbjct: 375  FGCSDCRKAFFEKSELIRHQTI-----HTGEKPYECSECRKAFRERSSLINHQRTH---- 425

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH  C  CG    Q   +  H+ + H G KP  C  C  + +R+ +L  HQ  
Sbjct: 426  ---TGEKPH-GCIQCGKAFSQKSHLISHQ-MTHTGEKPFICSKCGKAFSRKSQLVRHQRT 480

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F     L  H+ R+H     + C  C  +   +  +  H  + H 
Sbjct: 481  HTGEKPYECSECGKAFSEKLSLTNHQ-RIHTGEKPYVCSECGKAFCQKSHLISHQRT-HT 538

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + CS+C   F  +++L  H  R H             T E P  C  C       +
Sbjct: 539  GEKPYECSECGKAFGEKSSLATHQ-RTH-------------TGEKPYECRDCEKAFSQKS 584

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C++AF  +  L  H R       + C  C  A RE+  L+ 
Sbjct: 585  QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644

Query: 1398 HYL----EQHEETSAAVAASDGDGD--------AGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      E+  E S    A               G+ P  C  C      +  L +H + 
Sbjct: 645  HQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRI 704

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
            H G + Y+C +C  +   + ++  H R HT +K
Sbjct: 705  HTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737


>gi|34419633 zinc finger protein 135 [Homo sapiens]
          Length = 658

 Score =  228 bits (580), Expect = 5e-59
 Identities = 145/476 (30%), Positives = 199/476 (41%), Gaps = 38/476 (7%)

Query: 1172 QCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCS 1231
            +C +CG     S  + +H R  H G +P++C  C         L  HQ  HTG     C+
Sbjct: 215  KCQECGKAFSHSSALIEHHRT-HTGERPYECHECLKGFRNSSALTKHQRIHTGEKPYKCT 273

Query: 1232 SCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQC 1291
             C +TF   + L  H+ R H     + C  C  S   R   ++H  + H G   + CS+C
Sbjct: 274  QCGRTFNQIAPLIQHQ-RTHTGEKPYECSECGKSFSFRSSFSQHERT-HTGEKPYECSEC 331

Query: 1292 EAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ- 1350
               F     L QH LR H             T E P  C  CG      +SL  H R   
Sbjct: 332  GKAFRQSIHLTQH-LRIH-------------TGEKPYQCGECGKAFSHSSSLTKHQRIHT 377

Query: 1351 -HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETS 1407
                 EC  C +AF     L +H+R       + C  C  A  +   L +H         
Sbjct: 378  GEKPYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIH----- 432

Query: 1408 AAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKI 1467
                        G+ P  C  C  T  H   L  H + H G + Y+C+ C  + +    +
Sbjct: 433  -----------TGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHL 481

Query: 1468 TWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHM 1527
            T H RIHTGEKPY C+ C  A +  S L  H RIH  E+ Y C +CG     +  L  H 
Sbjct: 482  TQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQ 541

Query: 1528 TKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKH 1587
              HTG KPY+C +C    +++  L  HQ   H + + + C +CGK+F     L  H R H
Sbjct: 542  RIHTGEKPYECNQCGRAFSQSSLLIEHQRI-HTKEKPYGCNECGKSFSHSSSLSQHERTH 600

Query: 1588 SEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            +  KPY C+ C ++FR +  L  H   HT   P+ CR C         + KH R H
Sbjct: 601  TGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTH 656



 Score =  214 bits (545), Expect = 6e-55
 Identities = 141/453 (31%), Positives = 194/453 (42%), Gaps = 35/453 (7%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G RP+ +C +C    + S  + +H+R+ H G KP++C  C  +  +   L  HQ  HTG 
Sbjct: 238  GERPY-ECHECLKGFRNSSALTKHQRI-HTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGE 295

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                CS C ++F   S    H  R H     + C  C  +      +T+H+   H G   
Sbjct: 296  KPYECSECGKSFSFRSSFSQHE-RTHTGEKPYECSECGKAFRQSIHLTQHLR-IHTGEKP 353

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            + C +C   FS  ++L +H  R H             T E P  C  CG        L  
Sbjct: 354  YQCGECGKAFSHSSSLTKHQ-RIH-------------TGEKPYECHECGKAFTQITPLIQ 399

Query: 1346 HTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQH 1403
            H R        ECG C +AF     L EHRR  H   +   C+   +         L QH
Sbjct: 400  HQRTHTGEKPYECGECGKAFSQSTLLTEHRRI-HTGEKPYGCNECGKTFSH--SSSLSQH 456

Query: 1404 EETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKN 1463
            E T             G+ P  C  C    R    L  H + H G + Y+C DC  +  +
Sbjct: 457  ERTHT-----------GEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSH 505

Query: 1464 RQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQL 1523
               +T H RIHTGEKPY C+ C  A +  + L  H RIH  E+ Y C +CG      + L
Sbjct: 506  SSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLL 565

Query: 1524 KYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTH 1583
              H   HT  KPY C EC    + + +L  H+ T H   + + C  CGK+F+    L  H
Sbjct: 566  IEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERT-HTGEKPYECHDCGKSFRQSTHLTQH 624

Query: 1584 LRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHT 1616
             R H+  KPY C  C +AF  ++ L  H  THT
Sbjct: 625  RRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHT 657



 Score =  166 bits (421), Expect = 1e-40
 Identities = 114/440 (25%), Positives = 177/440 (40%), Gaps = 27/440 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F   + L+EH   H  +   +C  C K F + S L  H     GEK + 
Sbjct: 212 KPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKPYK 271

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +   L +H  +   +        Y C  C + F    +  +H ++HT    
Sbjct: 272 CTQCGRTFNQIAPLIQHQRTHTGE------KPYECSECGKSFSFRSSFSQHERTHTGEK- 324

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A        +HL+   G +  +C    C   F+ + ++  H + H
Sbjct: 325 ----PYECSE--CGKAFRQSIHLTQHLRIHTGEKPYQCGE--CGKAFSHSSSLTKHQRIH 376

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A +      +H++  H G +   C  C  A        +H  ++H  
Sbjct: 377 TGEKPYECHECGKAFTQITPLIQHQRT-HTGEKPYECGECGKAFSQSTLLTEH-RRIHTG 434

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK + C EC    +H   L +H   HTGEKP++C  C    R  ++L++H   H+  K Y
Sbjct: 435 EKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPY 494

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C +CG        L  H R H G+  Y+CNQC     +   L  H+  H G K   C  
Sbjct: 495 ECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQ 554

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A  +   L +H        T    Y C+ C     H  ++  HE   HT  + + C 
Sbjct: 555 CGRAFSQSSLLIEHQRIH----TKEKPYGCNECGKSFSHSSSLSQHER-THTGEKPYECH 609

Query: 577 LCDYRTFSNTTLLFHKRKAH 596
            C  ++F  +T L   R+ H
Sbjct: 610 DCG-KSFRQSTHLTQHRRIH 628



 Score =  156 bits (394), Expect = 2e-37
 Identities = 120/435 (27%), Positives = 171/435 (39%), Gaps = 52/435 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  Q   L  HQ        +GE    CS C  +    ++   H++      
Sbjct: 270  YKCTQCGRTFNQIAPLIQHQ-----RTHTGEKPYECSECGKSFSFRSSFSQHERTH---- 320

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG   +QS  + QH R+ H G KP+QC  C  + +    L  HQ  
Sbjct: 321  ---TGEKPY-ECSECGKAFRQSIHLTQHLRI-HTGEKPYQCGECGKAFSHSSSLTKHQRI 375

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C + F   + L  H+ R H     + C  C  +      +T H    H 
Sbjct: 376  HTGEKPYECHECGKAFTQITPLIQHQ-RTHTGEKPYECGECGKAFSQSTLLTEH-RRIHT 433

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C++C   FS  ++L QH  R H             T E P  CS+CG       
Sbjct: 434  GEKPYGCNECGKTFSHSSSLSQHE-RTH-------------TGEKPYECSQCGKAFRQST 479

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  H R        EC  C +AF    +L +H+R       + C  C  A  +   L++
Sbjct: 480  HLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQ 539

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H   Q   T             G+ P  C  C        +L  H + H   + Y C +C
Sbjct: 540  H---QRIHT-------------GEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNEC 583

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
              S  +   ++ H R HTGEKPY CH C  +    + L  H RIH  E+ Y C +CG   
Sbjct: 584  GKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAF 643

Query: 1518 KWVNQLKYHMTKHTG 1532
               + L  H   HTG
Sbjct: 644  THSSSLTKHQRTHTG 658



 Score =  155 bits (391), Expect = 4e-37
 Identities = 98/352 (27%), Positives = 151/352 (42%), Gaps = 20/352 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F++  HL +HL +H  +   QC  C K F+  S L  H     GEK + 
Sbjct: 324 KPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYE 383

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +   L +H  +   +        Y C  C + F  S  L EH + HT    
Sbjct: 384 CHECGKAFTQITPLIQHQRTHTGE------KPYECGECGKAFSQSTLLTEHRRIHTGEK- 436

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C + G +++     +  +H +   G +  EC    C   F  +  +  H + H
Sbjct: 437 ----PYGCNECGKTFS--HSSSLSQHERTHTGEKPYECSQ--CGKAFRQSTHLTQHQRIH 488

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S+     KH++  H G +   C  C  A F+ +A      ++H  
Sbjct: 489 TGEKPYECNDCGKAFSHSSSLTKHQRI-HTGEKPYECNQCGRA-FSQLAPLIQHQRIHTG 546

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  A +   +LI H  +HT EKP+ C  C  +    S LS+H  TH+  K Y
Sbjct: 547 EKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPY 606

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG 509
            C +CG   +   +L  H R H G+  Y C  C      +  L+ H+  H G
Sbjct: 607 ECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHTG 658



 Score =  150 bits (378), Expect = 1e-35
 Identities = 98/374 (26%), Positives = 151/374 (40%), Gaps = 21/374 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F  R+   +H   H  +   +C  C K F     L  HL    GEK + 
Sbjct: 296 KPYECSECGKSFSFRSSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQ 355

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +    ++L +H   +H          Y C  C + F     L +H ++HT    
Sbjct: 356 CGECGKAFSHSSSLTKHQR-IHTG-----EKPYECHECGKAFTQITPLIQHQRTHTGEK- 408

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C  A        +H +   G +   C  + C   F+ + ++  H ++H
Sbjct: 409 ----PYECGE--CGKAFSQSTLLTEHRRIHTGEKPYGC--NECGKTFSHSSSLSQHERTH 460

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A        +H++  H G +   C  C  A  +  +   H  ++H  
Sbjct: 461 TGEKPYECSQCGKAFRQSTHLTQHQRI-HTGEKPYECNDCGKAFSHSSSLTKHQ-RIHTG 518

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  A +    LI+H  +HTGEKP++C  C       S L +H   H+  K Y
Sbjct: 519 EKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPY 578

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG        L  H R H G+  Y+C+ C     ++  L+ H+  H G K   C  
Sbjct: 579 GCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRD 638

Query: 517 CAFACKRKYELQKH 530
           C  A      L KH
Sbjct: 639 CGKAFTHSSSLTKH 652



 Score =  149 bits (376), Expect = 2e-35
 Identities = 78/223 (34%), Positives = 100/223 (44%), Gaps = 1/223 (0%)

Query: 1421 QPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPY 1480
            + P  C  C     H   L  H + H G R Y+C +C    +N   +T H RIHTGEKPY
Sbjct: 211  EKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKPY 270

Query: 1481 HCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPE 1540
             C  C       + L  H R H  E+ Y C ECG    + +    H   HTG KPY+C E
Sbjct: 271  KCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSE 330

Query: 1541 CEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHR 1600
            C     ++  L  H    H   + + C +CGKAF     L  H R H+  KPY C+ C +
Sbjct: 331  CGKAFRQSIHLTQHLRI-HTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGK 389

Query: 1601 AFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            AF     L  H  THT   P+ C  C     Q   + +H R H
Sbjct: 390  AFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIH 432



 Score =  129 bits (324), Expect = 2e-29
 Identities = 81/282 (28%), Positives = 123/282 (43%), Gaps = 11/282 (3%)

Query: 323 CPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPF 379
           C   F+ + A+  HH++H     + C  C     N     KH++  H G +  +CT C  
Sbjct: 219 CGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRI-HTGEKPYKCTQCG- 276

Query: 380 ATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCR 439
            TFN +A      + H  EK ++C EC  + + +    +H   HTGEKP++C  C    R
Sbjct: 277 RTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSECGKAFR 336

Query: 440 DVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQ 499
              +L++H+  H+  K Y C ECG        L  H R H G+  Y+C++C     +   
Sbjct: 337 QSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITP 396

Query: 500 LSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQA 558
           L  H+  H G K   C  C  A  +   L +H   + H G     Y C+ C     H  +
Sbjct: 397 LIQHQRTHTGEKPYECGECGKAFSQSTLLTEHR--RIHTGEKP--YGCNECGKTFSHSSS 452

Query: 559 VLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           +  HE   HT  + + C+ C      +T L  H+R   G  P
Sbjct: 453 LSQHERT-HTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKP 493



 Score =  109 bits (273), Expect = 2e-23
 Identities = 64/204 (31%), Positives = 91/204 (44%), Gaps = 6/204 (2%)

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A +H   LI H   HTGE+P++C  C    R+ S L+KH   H+  K Y
Sbjct: 211 EKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKPY 270

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            CT+CG        L  H R H G+  Y+C++C          S H+  H G K   C  
Sbjct: 271 KCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSE 330

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A ++   L +H+  + H G     Y C  C     H  ++  H+   HT  + + C 
Sbjct: 331 CGKAFRQSIHLTQHL--RIHTGEKP--YQCGECGKAFSHSSSLTKHQRI-HTGEKPYECH 385

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C       T L+ H+R   G  P
Sbjct: 386 ECGKAFTQITPLIQHQRTHTGEKP 409



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 47/140 (33%), Positives = 67/140 (47%), Gaps = 1/140 (0%)

Query: 1504 EERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREAR 1563
            +E+ Y C ECG      + L  H   HTG +PY+C EC      + AL  HQ   H   +
Sbjct: 210  KEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRI-HTGEK 268

Query: 1564 AFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFC 1623
             + C QCG+ F     L  H R H+  KPY C+ C ++F + +    H  THT   P+ C
Sbjct: 269  PYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYEC 328

Query: 1624 RLCNYKAKQKFQVVKHVRRH 1643
              C    +Q   + +H+R H
Sbjct: 329  SECGKAFRQSIHLTQHLRIH 348


>gi|154091003 zinc finger protein 470 [Homo sapiens]
          Length = 717

 Score =  227 bits (578), Expect = 8e-59
 Identities = 155/535 (28%), Positives = 218/535 (40%), Gaps = 48/535 (8%)

Query: 1116 ERALRTHQIRGCPLEESGE---LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQ 1172
            +++L+TH +     ++ GE   L C+ C       + L LHQ+          G +P+ +
Sbjct: 206  KKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIH-------TGEKPY-E 257

Query: 1173 CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
            C +CG    QS  + QH+R+ H G KP +C  C  + ++   L  HQ  HTG     C  
Sbjct: 258  CIECGKAFSQSAHLAQHQRI-HTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQ 316

Query: 1233 CPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCE 1292
            C + F   + L  H+ RVH     + C  C    +       H    H G   + C  C 
Sbjct: 317  CNKAFSQLAHLAQHQ-RVHTGEKPYECIECG-KAFSDCSSLAHHRRIHTGKRPYECIDCG 374

Query: 1293 AQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP 1352
              F    +L +H    H             T E P  C  CG        L  H R    
Sbjct: 375  KAFRQNASLIRHRRYYH-------------TGEKPFDCIDCGKAFTDHIGLIQHKRTHTG 421

Query: 1353 R--LECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSA 1408
                +C  C +AF    +L  H+R       + C +C+ A   R  L  H   Q   T  
Sbjct: 422  ERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLH---QRVHT-- 476

Query: 1409 AVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKIT 1468
                       G+ P  C  C    R    L HH + H G + Y+C +C+ +      + 
Sbjct: 477  -----------GEKPYECKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLA 525

Query: 1469 WHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMT 1528
             H +IHTGEKPY C  C  A +  + L  H R+H  E+ Y C ECG      + L  H  
Sbjct: 526  QHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQR 585

Query: 1529 KHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHS 1588
             H+G +PY+C EC     +  +L  HQ   H   + + C  CGKAF  R  L  H R H+
Sbjct: 586  LHSGKRPYECLECGKAFRQRASLICHQRC-HTGEKPYECNVCGKAFSHRKSLTLHQRIHT 644

Query: 1589 EAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
              KPY C  C +AF   A L  H   HT   P+ C+ C    +Q   +  H R H
Sbjct: 645  GEKPYECKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIH 699



 Score =  172 bits (436), Expect = 2e-42
 Identities = 121/441 (27%), Positives = 184/441 (41%), Gaps = 28/441 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC + F +  HLV+H  +H  +   QC  C K F+  + L  H     GEK + 
Sbjct: 282 KPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYE 341

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLK-SHTAAA 279
           C  C  +  + ++L  H   +H          Y C  C + FR + +L  H +  HT   
Sbjct: 342 CIECGKAFSDCSSLAHH-RRIHTG-----KRPYECIDCGKAFRQNASLIRHRRYYHTGEK 395

Query: 280 AAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKS 339
                P  C    C  A  D    I+H +   G R  +C  + C   F+   ++  H + 
Sbjct: 396 -----PFDCID--CGKAFTDHIGLIQHKRTHTGERPYKC--NVCGKAFSHGSSLTVHQRI 446

Query: 340 HYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHA 396
           H     + C  C+ A S++     H++  H G +   C  C  A F    +  H  ++H 
Sbjct: 447 HTGEKPYECNICEKAFSHRGSLTLHQRV-HTGEKPYECKECGKA-FRQSTHLAHHQRIHT 504

Query: 397 HEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKD 456
            EK ++C EC+   +    L +H  +HTGEKP++C+ C      +++L +H   H+  K 
Sbjct: 505 GEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKP 564

Query: 457 YMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCE 515
           Y C ECG       YL  H R H+G   Y+C +C     +   L  H+  H G K   C 
Sbjct: 565 YECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPYECN 624

Query: 516 VCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHC 575
           VC  A   +  L  H   + H G     Y C  CS        +  H+   HT  R + C
Sbjct: 625 VCGKAFSHRKSLTLH--QRIHTGEKP--YECKECSKAFSQVAHLTLHKRI-HTGERPYEC 679

Query: 576 ALCDYRTFSNTTLLFHKRKAH 596
             C  + F  +  L H ++ H
Sbjct: 680 KECG-KAFRQSVHLAHHQRIH 699



 Score =  159 bits (401), Expect = 3e-38
 Identities = 120/451 (26%), Positives = 183/451 (40%), Gaps = 30/451 (6%)

Query: 155 GTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLREL 214
           G + L K   C +C++ F K + L  H  +H  +   +C  C K F+  + L  H     
Sbjct: 223 GEKKLLK---CNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHT 279

Query: 215 GEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKS 274
           GEK   C  C   A  +NA   H+   H+ + +     Y C  C + F     L +H + 
Sbjct: 280 GEKPFECTECG-KAFSQNA---HLV-QHQRV-HTGEKPYQCKQCNKAFSQLAHLAQHQRV 333

Query: 275 HTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAME 334
           HT        P  C +  C  A  D  +   H +   G R  EC    C   F    ++ 
Sbjct: 334 HTGEK-----PYECIE--CGKAFSDCSSLAHHRRIHTGKRPYEC--IDCGKAFRQNASLI 384

Query: 335 AH----HKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDH 390
            H    H     F C  C  A ++ H+     K+ H G    +C  C  A  +  +   H
Sbjct: 385 RHRRYYHTGEKPFDCIDCGKAFTD-HIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLTVH 443

Query: 391 VGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLT 450
             ++H  EK ++C  C  A +H+  L  H  +HTGEKP++C+ C    R  ++L+ H   
Sbjct: 444 -QRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECKECGKAFRQSTHLAHHQRI 502

Query: 451 HSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG- 509
           H+  K Y C EC        +L  H + H G+  Y+C +C     +   L  H+  H G 
Sbjct: 503 HTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGE 562

Query: 510 KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTR 569
           K   C  C  A      L +H   + H G     Y C  C    R + +++ H+ C HT 
Sbjct: 563 KPYECIECGKAFSDGSYLVQH--QRLHSGKRP--YECLECGKAFRQRASLICHQRC-HTG 617

Query: 570 LREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + + C +C        +L  H+R   G  P
Sbjct: 618 EKPYECNVCGKAFSHRKSLTLHQRIHTGEKP 648



 Score =  150 bits (379), Expect = 1e-35
 Identities = 95/327 (29%), Positives = 132/327 (40%), Gaps = 20/327 (6%)

Query: 1320 PAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFP--SRLALDEHRRQQH 1377
            P E      H  +  L   S        R +   L+C  C++ F   S L L +      
Sbjct: 194  PMEERIFNFHTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGE 253

Query: 1378 FSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQL 1437
              + C  C  A  +       +L QH+               G+ P  C  C        
Sbjct: 254  KPYECIECGKAFSQSA-----HLAQHQRI-----------HTGEKPFECTECGKAFSQNA 297

Query: 1438 VLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKY 1497
             L  H + H G + Y+C  C  +      +  H R+HTGEKPY C  C  A +D S L +
Sbjct: 298  HLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAH 357

Query: 1498 HMRIHKEERKYLCPECGYKCKW-VNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQE 1556
            H RIH  +R Y C +CG   +   + +++    HTG KP+ C +C         L  H+ 
Sbjct: 358  HRRIHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKR 417

Query: 1557 TRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHT 1616
            T H   R + C  CGKAF     L  H R H+  KPY CN+C +AF     L  H   HT
Sbjct: 418  T-HTGERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHT 476

Query: 1617 DRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
               P+ C+ C    +Q   +  H R H
Sbjct: 477  GEKPYECKECGKAFRQSTHLAHHQRIH 503



 Score =  147 bits (370), Expect = 1e-34
 Identities = 113/441 (25%), Positives = 180/441 (40%), Gaps = 35/441 (7%)

Query: 169 KRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSA 228
           K+  K  + + +H         L+C +C+K F+  S L  H     GEK + C  C   A
Sbjct: 206 KKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECG-KA 264

Query: 229 VERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRC 288
             ++A   H+A  H+ I +     + C  C + F  +  L +H + HT        P +C
Sbjct: 265 FSQSA---HLA-QHQRI-HTGEKPFECTECGKAFSQNAHLVQHQRVHTGEK-----PYQC 314

Query: 289 FQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHC 345
            Q  C+ A        +H +   G +  EC    C   F+   ++  H + H     + C
Sbjct: 315 KQ--CNKAFSQLAHLAQHQRVHTGEKPYEC--IECGKAFSDCSSLAHHRRIHTGKRPYEC 370

Query: 346 PHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVG-----KMHAHEKI 400
             C  A        +H++  H G +   C  C        A+ DH+G     + H  E+ 
Sbjct: 371 IDCGKAFRQNASLIRHRRYYHTGEKPFDCIDC------GKAFTDHIGLIQHKRTHTGERP 424

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCT 460
           ++C  C  A +H   L  H  +HTGEKP++C +C+        L+ H   H+  K Y C 
Sbjct: 425 YKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECK 484

Query: 461 ECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAF 519
           ECG   +   +L  H R H G+  Y+C +CS    +   L+ H+  H G K   C+ C  
Sbjct: 485 ECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGK 544

Query: 520 ACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 579
           A  +   L +H   + H G     Y C  C         ++ H+   H+  R + C  C 
Sbjct: 545 AFSQIAHLVQH--QRVHTGEKP--YECIECGKAFSDGSYLVQHQRL-HSGKRPYECLECG 599

Query: 580 YRTFSNTTLLFHKRKAHGYVP 600
                  +L+ H+R   G  P
Sbjct: 600 KAFRQRASLICHQRCHTGEKP 620



 Score =  134 bits (338), Expect = 6e-31
 Identities = 98/403 (24%), Positives = 154/403 (38%), Gaps = 61/403 (15%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C + F +  HL +H  +H  +   +C  C K F+  S L  H     G++ + 
Sbjct: 310 KPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYE 369

Query: 221 CPLCHYSAVERNALNRHMASMHE--------DISNFYSD---------------TYACPV 257
           C  C  +  +  +L RH    H         D    ++D                Y C V
Sbjct: 370 CIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHTGERPYKCNV 429

Query: 258 CREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVE 317
           C + F    +L  H + HT        P  C    C  A   R +   H +   G +  E
Sbjct: 430 CGKAFSHGSSLTVHQRIHTGEK-----PYEC--NICEKAFSHRGSLTLHQRVHTGEKPYE 482

Query: 318 CR-------------HHS-------------CPMLFATAEAMEAHHKSHYA---FHCPHC 348
           C+             HH              C   F+    +  H K H     + C  C
Sbjct: 483 CKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKEC 542

Query: 349 DFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNF 408
             A S      +H++  H G +   C  C  A F+  +Y     ++H+ ++ ++C EC  
Sbjct: 543 GKAFSQIAHLVQHQRV-HTGEKPYECIECGKA-FSDGSYLVQHQRLHSGKRPYECLECGK 600

Query: 409 ATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKW 468
           A   +  LI H   HTGEKP++C +C         L+ H   H+  K Y C EC      
Sbjct: 601 AFRQRASLICHQRCHTGEKPYECNVCGKAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQ 660

Query: 469 KHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKS 511
             +L +H R H G+  Y+C +C     ++  L+ H+  H G+S
Sbjct: 661 VAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGES 703



 Score =  112 bits (280), Expect = 3e-24
 Identities = 61/185 (32%), Positives = 84/185 (45%), Gaps = 1/185 (0%)

Query: 1460 STKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            S K    +  H +    +K   C+ C    +  S L  H RIH  E+ Y C ECG     
Sbjct: 208  SLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQ 267

Query: 1520 VNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFL 1579
               L  H   HTG KP++C EC    ++   L  HQ   H   + + C+QC KAF     
Sbjct: 268  SAHLAQHQRIHTGEKPFECTECGKAFSQNAHLVQHQRV-HTGEKPYQCKQCNKAFSQLAH 326

Query: 1580 LRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKH 1639
            L  H R H+  KPY C  C +AF   + L HH   HT + P+ C  C    +Q   +++H
Sbjct: 327  LAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIRH 386

Query: 1640 VRRHH 1644
             R +H
Sbjct: 387  RRYYH 391



 Score =  102 bits (255), Expect = 2e-21
 Identities = 67/255 (26%), Positives = 103/255 (40%), Gaps = 6/255 (2%)

Query: 347 HCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPEC 406
           H D      H   K  KQ     + L+C  C    F+ ++      ++H  EK ++C EC
Sbjct: 203 HTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCE-KIFSKISTLTLHQRIHTGEKPYECIEC 261

Query: 407 NFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVT 466
             A +    L +H  +HTGEKP +C  C       ++L +H   H+  K Y C +C    
Sbjct: 262 GKAFSQSAHLAQHQRIHTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAF 321

Query: 467 KWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK-SLMCEVCAFACKRKY 525
               +L  H R H G+  Y+C +C         L+ H+  H GK    C  C  A ++  
Sbjct: 322 SQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNA 381

Query: 526 ELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSN 585
            L +H    H    P   + C  C         ++ H+   HT  R + C +C       
Sbjct: 382 SLIRHRRYYHTGEKP---FDCIDCGKAFTDHIGLIQHKR-THTGERPYKCNVCGKAFSHG 437

Query: 586 TTLLFHKRKAHGYVP 600
           ++L  H+R   G  P
Sbjct: 438 SSLTVHQRIHTGEKP 452



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 55/168 (32%), Positives = 77/168 (45%), Gaps = 2/168 (1%)

Query: 1477 EKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPY 1536
            E+ ++ H    +    S +K H +   E++   C +C      ++ L  H   HTG KPY
Sbjct: 197  ERIFNFHTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPY 256

Query: 1537 QCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCN 1596
            +C EC    +++  L  HQ   H   + F C +CGKAF     L  H R H+  KPY C 
Sbjct: 257  ECIECGKAFSQSAHLAQHQRI-HTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCK 315

Query: 1597 VCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHH 1644
             C++AF   A L  H   HT   P+ C  C  KA      + H RR H
Sbjct: 316  QCNKAFSQLAHLAQHQRVHTGEKPYECIECG-KAFSDCSSLAHHRRIH 362



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 24/143 (16%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F   ++LV+H  LH      +C  C K F  ++ L  H     GEK + 
Sbjct: 563 KPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPYE 622

Query: 221 CPLCHYSAVERNALNRHMASMH--------EDISNFYSDT---------------YACPV 257
           C +C  +   R +L  H   +H        ++ S  +S                 Y C  
Sbjct: 623 CNVCGKAFSHRKSLTLHQR-IHTGEKPYECKECSKAFSQVAHLTLHKRIHTGERPYECKE 681

Query: 258 CREEFRLSQALKEHLKSHTAAAA 280
           C + FR S  L  H + HT  ++
Sbjct: 682 CGKAFRQSVHLAHHQRIHTGESS 704



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 35/226 (15%)

Query: 1011 SPTEALKKHRFEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSP 1070
            S T +   H  +  K H    P+ C       S +A   +  R   G++           
Sbjct: 515  SKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEK----------- 563

Query: 1071 LSNGDSAPPKNGSTESSSGDGDTVLVQKQK---GAR-FSCPTCPFSCQQERALRTHQIRG 1126
                   P +      +  DG + LVQ Q+   G R + C  C  + +Q  +L  HQ   
Sbjct: 564  -------PYECIECGKAFSDG-SYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQ--R 613

Query: 1127 CPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCM 1186
            C   E     C++C        +L LHQ+          G +P+ +C +C     Q   +
Sbjct: 614  CHTGEK-PYECNVCGKAFSHRKSLTLHQRIH-------TGEKPY-ECKECSKAFSQVAHL 664

Query: 1187 QQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
              H+R+ H G +P++C  C  +  +   L  HQ  HTG   +  SS
Sbjct: 665  TLHKRI-HTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVILSS 709



 Score = 34.7 bits (78), Expect = 0.81
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 6/57 (10%)

Query: 830 QGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           +GE +  +C  C  I  +   L LH R  TG     +P  C ECG +F Q   L+ H
Sbjct: 222 RGEKKLLKCNDCEKIFSKISTLTLHQRIHTG----EKPYECIECGKAFSQSAHLAQH 274


>gi|157167158 zinc finger protein 808 [Homo sapiens]
          Length = 903

 Score =  227 bits (578), Expect = 8e-59
 Identities = 143/496 (28%), Positives = 211/496 (42%), Gaps = 39/496 (7%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P+ +C +C     Q   +++H+R+ H G KP++C  CD + T   +L  H+  HTG 
Sbjct: 423  GEKPY-KCEECDKVFSQKSTLERHKRI-HTGEKPYKCKVCDTAFTCNSQLARHRRIHTGE 480

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C +TF   S L  HR R+H     + C  C  +   R  +  H    H    +
Sbjct: 481  KTYKCNECRKTFSRRSSLLCHR-RLHSGEKPYKCNQCGNTFRHRASLVYH-RRLHTLEKS 538

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            + C+ C   F   + L  H  R H             T + P  C+ CG      + L  
Sbjct: 539  YKCTVCNKVFMRNSVLAVHT-RIH-------------TAKKPYKCNECGKAFNQQSHLSR 584

Query: 1346 HTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHY-L 1400
            H R        +C AC + F  + AL+ H+R       +RCQ+CD A      L +H  +
Sbjct: 585  HRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRI 644

Query: 1401 EQHEETSAAVAASDGDG-----------DAGQPPLHCPFCD--FTCRHQLVLDHHVKGHG 1447
               E+T                        G+    C  CD  F CR  +    H + H 
Sbjct: 645  HTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVA--KHTRIHS 702

Query: 1448 GTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERK 1507
            G + YKC +C+ +  NR  +  H RIH+GEKPY C  C    +  + L  H R+H  E+ 
Sbjct: 703  GMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKP 762

Query: 1508 YLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMC 1567
            Y C +CG   +  + L YH   HTG K Y+C  C+    R   L  H    H   + + C
Sbjct: 763  YKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRI-HTAEKPYKC 821

Query: 1568 EQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCN 1627
             +CGKAF  +  L  H R H+  KPY C  C + F   + L+ H + HT   P+ C  C 
Sbjct: 822  NECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECG 881

Query: 1628 YKAKQKFQVVKHVRRH 1643
                 +  ++ H   H
Sbjct: 882  KAFSDRSTLIHHQAIH 897



 Score =  220 bits (561), Expect = 8e-57
 Identities = 159/585 (27%), Positives = 238/585 (40%), Gaps = 73/585 (12%)

Query: 1103 RFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAA 1162
            ++ C  C      ++ L  H  R C   E     C  C  +    ++L  H +       
Sbjct: 258  QYKCDVCGKLFNHKQYLACH--RRCHTGEK-PYKCKECGKSFSYKSSLTCHHRLH----- 309

Query: 1163 PARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRH 1222
               G +P+ +C +CG   +Q+  +  H+ + H G KP++C  C  +  ++  L  HQ  H
Sbjct: 310  --TGVKPY-KCNECGKVFRQNSALVIHKAI-HTGEKPYKCNECGKAFNQQSHLSRHQRLH 365

Query: 1223 TGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQG 1282
            TG+    C  C + F  +S L  H  R+H    T+ C  C  +   +  + RH +  H G
Sbjct: 366  TGVKPYKCKICEKAFACHSYLANHT-RIHSGEKTYKCNECGKAFNHQSSLARH-HILHTG 423

Query: 1283 TPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPAS 1342
               + C +C+  FS ++ L++H  R H             T E P  C  C       + 
Sbjct: 424  EKPYKCEECDKVFSQKSTLERHK-RIH-------------TGEKPYKCKVCDTAFTCNSQ 469

Query: 1343 LRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFS--HRCQLCDFAARERVGLVKH 1398
            L  H R        +C  C++ F  R +L  HRR       ++C  C    R R  LV H
Sbjct: 470  LARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYH 529

Query: 1399 Y----LEQHEETSA--------AVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGH 1446
                 LE+  + +         +V A        + P  C  C      Q  L  H + H
Sbjct: 530  RRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLH 589

Query: 1447 GGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEER 1506
             G + YKC  C      +  +  H RIHTGEKPY C +C  A    S+L  H RIH  E+
Sbjct: 590  TGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEK 649

Query: 1507 KYLCPECG---------------------YKCKWVNQ-------LKYHMTKHTGLKPYQC 1538
             Y C ECG                     YKCK  ++       +  H   H+G+KPY+C
Sbjct: 650  TYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKC 709

Query: 1539 PECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVC 1598
             EC    +   +L  H+   H   + + C +C K F  +  L  H R HS  KPY CN C
Sbjct: 710  NECSKTFSNRSSLVCHRRI-HSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDC 768

Query: 1599 HRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
               FR  + L +H   HT    + C +C+    +   + +H+R H
Sbjct: 769  GNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIH 813



 Score =  207 bits (526), Expect = 9e-53
 Identities = 148/523 (28%), Positives = 208/523 (39%), Gaps = 88/523 (16%)

Query: 1128 PLEESGE-LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCM 1186
            P  ESG+  +CS         + LR HQ        P  G + + +C  CG      + +
Sbjct: 232  PCNESGKAFNCS---------SLLRKHQ-------IPHLGDKQY-KCDVCGKLFNHKQYL 274

Query: 1187 QQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLH 1246
              HRR  H G KP++C  C  S + +  L  H   HTG+    C+ C + F  NS L +H
Sbjct: 275  ACHRRC-HTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIH 333

Query: 1247 RLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHAL 1306
            +                              + H G   + C++C   F+ ++ L +H  
Sbjct: 334  K------------------------------AIHTGEKPYKCNECGKAFNQQSHLSRHQ- 362

Query: 1307 RRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR--KQHPRLECGACQEAFP 1364
            R H             T   P  C  C       + L  HTR        +C  C +AF 
Sbjct: 363  RLH-------------TGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFN 409

Query: 1365 SRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQP 1422
             + +L  H         ++C+ CD     +V   K  LE+H+               G+ 
Sbjct: 410  HQSSLARHHILHTGEKPYKCEECD-----KVFSQKSTLERHKRIHT-----------GEK 453

Query: 1423 PLHCPFCD--FTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPY 1480
            P  C  CD  FTC  QL    H + H G + YKC +C  +   R  +  H R+H+GEKPY
Sbjct: 454  PYKCKVCDTAFTCNSQLA--RHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPY 511

Query: 1481 HCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPE 1540
             C+ C       + L YH R+H  E+ Y C  C       + L  H   HT  KPY+C E
Sbjct: 512  KCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNE 571

Query: 1541 CEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHR 1600
            C    N+   L  H+   H   + + CE C K F  +  L +H R H+  KPY C VC  
Sbjct: 572  CGKAFNQQSHLSRHRRL-HTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDT 630

Query: 1601 AFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            AF W + L  H   HT    + C  C      K  +V H R H
Sbjct: 631  AFTWNSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLH 673



 Score =  188 bits (478), Expect = 3e-47
 Identities = 142/506 (28%), Positives = 212/506 (41%), Gaps = 49/506 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C     Q+  L  H+        +GE    C +C       + L  H +R H   
Sbjct: 427  YKCEECDKVFSQKSTLERHK-----RIHTGEKPYKCKVCDTAFTCNSQLARH-RRIHT-- 478

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G + + +C +C  T  +   +  HRRL H G KP++C  C  +   R  L  H+  
Sbjct: 479  ----GEKTY-KCNECRKTFSRRSSLLCHRRL-HSGEKPYKCNQCGNTFRHRASLVYHRRL 532

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HT      C+ C + F  NS L +H  R+H     + C  C  +   +  ++RH    H 
Sbjct: 533  HTLEKSYKCTVCNKVFMRNSVLAVHT-RIHTAKKPYKCNECGKAFNQQSHLSRH-RRLHT 590

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C  C+  F  ++AL+ H  R H             T E P  C  C       +
Sbjct: 591  GEKPYKCEACDKVFGQKSALESHK-RIH-------------TGEKPYRCQVCDTAFTWNS 636

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVK 1397
             L  HTR        +C  C + F  + +L  HRR      S++C++CD A   R  + K
Sbjct: 637  QLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAK 696

Query: 1398 HY-----LEQHEETSAAVAASDGDG-------DAGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            H      ++ ++    +   S+           +G+ P  C  C  T   +  L  H + 
Sbjct: 697  HTRIHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRL 756

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEE 1505
            H G + YKC DC  + ++   + +H R+HTGEK Y C +C  A    S L  H+RIH  E
Sbjct: 757  HSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAE 816

Query: 1506 RKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAF 1565
            + Y C ECG      + L  H   HTG KPY+C  C+   +R   L+ H+   H   + +
Sbjct: 817  KPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHR-IIHTGEKPY 875

Query: 1566 MCEQCGKAFKTRFLLRTHLRKHSEAK 1591
             C +CGKAF  R  L  H   H   K
Sbjct: 876  KCNECGKAFSDRSTLIHHQAIHGIGK 901



 Score =  178 bits (451), Expect = 5e-44
 Identities = 125/446 (28%), Positives = 186/446 (41%), Gaps = 30/446 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F +++HL  H  LH      +C  C+K F   S L  H     GEK + 
Sbjct: 341 KPYKCNECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYK 400

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   +++L RH       I +     Y C  C + F     L+ H + HT    
Sbjct: 401 CNECGKAFNHQSSLARH------HILHTGEKPYKCEECDKVFSQKSTLERHKRIHTGEK- 453

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C  + C  A        +H +   G +  +C  + C   F+   ++  H + H
Sbjct: 454 ----PYKC--KVCDTAFTCNSQLARHRRIHTGEKTYKC--NECRKTFSRRSSLLCHRRLH 505

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C     ++     H++  H   +  +CT C            H  ++H  
Sbjct: 506 SGEKPYKCNQCGNTFRHRASLVYHRRL-HTLEKSYKCTVCNKVFMRNSVLAVHT-RIHTA 563

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           +K ++C EC  A   +  L RH  LHTGEKP+KCE CD      S L  H   H+  K Y
Sbjct: 564 KKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPY 623

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C  C     W   L  H R H G+  Y+CN+C         L  H+  H G KS  C+V
Sbjct: 624 RCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKV 683

Query: 517 C--AFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
           C  AF C R Y + KH  ++ H G     Y C+ CS    ++ +++ H    H+  + + 
Sbjct: 684 CDKAFVC-RSY-VAKH--TRIHSGMKP--YKCNECSKTFSNRSSLVCHRRI-HSGEKPYK 736

Query: 575 CALCDYRTFSNTTLLFHKRKAHGYVP 600
           C+ C        TLL H+R   G  P
Sbjct: 737 CSECSKTFSQKATLLCHRRLHSGEKP 762



 Score =  171 bits (432), Expect = 7e-42
 Identities = 122/465 (26%), Positives = 187/465 (40%), Gaps = 47/465 (10%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C  C   F   + L  H  +H  + + +C  C+K F+ +S L  H     GEK + 
Sbjct: 453 KPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYK 512

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R +L  H   +H         +Y C VC + F  +  L  H + HTA   
Sbjct: 513 CNQCGNTFRHRASLVYHRR-LHT-----LEKSYKCTVCNKVFMRNSVLAVHTRIHTAKK- 565

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  C  A   +    +H +   G +  +C   +C  +F    A+E+H + H
Sbjct: 566 ----PYKCNE--CGKAFNQQSHLSRHRRLHTGEKPYKCE--ACDKVFGQKSALESHKRIH 617

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD A +      +H +  H G +  +C  C   TF+  +      ++H  
Sbjct: 618 TGEKPYRCQVCDTAFTWNSQLARHTRI-HTGEKTYKCNECG-KTFSYKSSLVWHRRLHGG 675

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C  C+ A   +  + +H  +H+G KP+KC  C  T  + S L  H   HS  K Y
Sbjct: 676 EKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPY 735

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C+EC      K  L  H R H+G+  Y+CN C         L  H+  H G KS  C V
Sbjct: 736 KCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTV 795

Query: 517 CAFA------------------------CKRKYELQKHMASQHHPGTPAPLYPCHYCSYQ 552
           C  A                        C + +  Q H++  H   T    Y C  C   
Sbjct: 796 CDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKV 855

Query: 553 SRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHG 597
              K  +  H    HT  + + C  C  + FS+ + L H +  HG
Sbjct: 856 FSRKSHLKRH-RIIHTGEKPYKCNECG-KAFSDRSTLIHHQAIHG 898



 Score =  169 bits (427), Expect = 3e-41
 Identities = 134/495 (27%), Positives = 194/495 (39%), Gaps = 40/495 (8%)

Query: 111 PLPGQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLE----GDVVSGTESLFKTHMCP 166
           PL      +++ V   EKS    +S KA +     ++ +    GD         K + C 
Sbjct: 212 PLNSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGD---------KQYKCD 262

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHY 226
            C + F  + +L  H   H  +   +C  C K F+ KS L  H     G K + C  C  
Sbjct: 263 VCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGK 322

Query: 227 SAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPL 286
              + +AL  H A +H          Y C  C + F     L  H + HT        P 
Sbjct: 323 VFRQNSALVIHKA-IHTG-----EKPYKCNECGKAFNQQSHLSRHQRLHTGVK-----PY 371

Query: 287 RCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---F 343
           +C  + C  A         H +   G +  +C  + C   F    ++  HH  H     +
Sbjct: 372 KC--KICEKAFACHSYLANHTRIHSGEKTYKC--NECGKAFNHQSSLARHHILHTGEKPY 427

Query: 344 HCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQC 403
            C  CD   S K    +HK+  H G +  +C  C  A F   +      ++H  EK ++C
Sbjct: 428 KCEECDKVFSQKSTLERHKRI-HTGEKPYKCKVCDTA-FTCNSQLARHRRIHTGEKTYKC 485

Query: 404 PECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECG 463
            EC    + +  L+ H  LH+GEKP+KC  C  T R  + L  H   H+  K Y CT C 
Sbjct: 486 NECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCN 545

Query: 464 YVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACK 522
            V      L VH R H     Y+CN+C    ++   LS H+  H G K   CE C     
Sbjct: 546 KVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFG 605

Query: 523 RKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRT 582
           +K  L+ H   + H G     Y C  C         +  H    HT  + + C  C  +T
Sbjct: 606 QKSALESH--KRIHTGEKP--YRCQVCDTAFTWNSQLARHTRI-HTGEKTYKCNECG-KT 659

Query: 583 FSNTTLLFHKRKAHG 597
           FS  + L   R+ HG
Sbjct: 660 FSYKSSLVWHRRLHG 674



 Score =  158 bits (400), Expect = 4e-38
 Identities = 125/447 (27%), Positives = 182/447 (40%), Gaps = 60/447 (13%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K+  C E  + F   + L +H   H  D   +C  C K F  K  L  H     GEK + 
Sbjct: 229 KSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYK 288

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  S   +++L  H   +H  +       Y C  C + FR + AL  H   HT    
Sbjct: 289 CKECGKSFSYKSSLTCHHR-LHTGVK-----PYKCNECGKVFRQNSALVIHKAIHTGEK- 341

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P +C +  C  A   +    +H +   GV+  +C+   C   FA    +  H   H
Sbjct: 342 ----PYKCNE--CGKAFNQQSHLSRHQRLHTGVKPYKCK--ICEKAFACHSYLANHTRIH 393

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A +++    +H                            H+  +H  
Sbjct: 394 SGEKTYKCNECGKAFNHQSSLARH----------------------------HI--LHTG 423

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCD--FTCRDVSYLSKHMLTHSNTK 455
           EK ++C EC+   + K  L RH  +HTGEKP+KC++CD  FTC   S L++H   H+  K
Sbjct: 424 EKPYKCEECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCN--SQLARHRRIHTGEK 481

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC--SYRCHRADQLSSHKLRHQGKSLM 513
            Y C EC      +  L  H R H+G+  Y+CNQC  ++R HRA  +   +L    KS  
Sbjct: 482 TYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFR-HRASLVYHRRLHTLEKSYK 540

Query: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C VC     R   L  H        T    Y C+ C  ++ ++Q+ LS     HT  + +
Sbjct: 541 CTVCNKVFMRNSVLAVHTRIH----TAKKPYKCNECG-KAFNQQSHLSRHRRLHTGEKPY 595

Query: 574 HCALCDYRTFSNTTLLFHKRKAHGYVP 600
            C  CD      + L  HKR   G  P
Sbjct: 596 KCEACDKVFGQKSALESHKRIHTGEKP 622



 Score =  157 bits (397), Expect = 8e-38
 Identities = 103/379 (27%), Positives = 162/379 (42%), Gaps = 21/379 (5%)

Query: 158 SLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEK 217
           +L K++ C  C + F + + L  H  +H      +C  C K F  +S L  H     GEK
Sbjct: 534 TLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEK 593

Query: 218 AHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTA 277
            + C  C     +++AL  H   +H          Y C VC   F  +  L  H + HT 
Sbjct: 594 PYKCEACDKVFGQKSALESHKR-IHTG-----EKPYRCQVCDTAFTWNSQLARHTRIHTG 647

Query: 278 AAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHH 337
                    +C + G +++   + + + H +   G ++ +C+   C   F     +  H 
Sbjct: 648 EKT-----YKCNECGKTFSY--KSSLVWHRRLHGGEKSYKCK--VCDKAFVCRSYVAKHT 698

Query: 338 KSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKM 394
           + H     + C  C    SN+     H++  H G +  +C+ C   TF+  A      ++
Sbjct: 699 RIHSGMKPYKCNECSKTFSNRSSLVCHRRI-HSGEKPYKCSECS-KTFSQKATLLCHRRL 756

Query: 395 HAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNT 454
           H+ EK ++C +C     H   L+ H  LHTGEK +KC +CD      SYL++H+  H+  
Sbjct: 757 HSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAE 816

Query: 455 KDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLM 513
           K Y C ECG     + +L  H R H G+  Y+C  C     R   L  H++ H G K   
Sbjct: 817 KPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYK 876

Query: 514 CEVCAFACKRKYELQKHMA 532
           C  C  A   +  L  H A
Sbjct: 877 CNECGKAFSDRSTLIHHQA 895



 Score =  115 bits (288), Expect = 4e-25
 Identities = 60/199 (30%), Positives = 88/199 (44%), Gaps = 5/199 (2%)

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEE 1505
            H   + + C +   +      +  H   H G+K Y C +C         L  H R H  E
Sbjct: 225  HMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGE 284

Query: 1506 RKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAF 1565
            + Y C ECG    + + L  H   HTG+KPY+C EC     +  AL +H+   H   + +
Sbjct: 285  KPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAI-HTGEKPY 343

Query: 1566 MCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRL 1625
             C +CGKAF  +  L  H R H+  KPY C +C +AF   + L +H   H+    + C  
Sbjct: 344  KCNECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNE 403

Query: 1626 CNYKAKQKFQVVKHVRRHH 1644
            C     + F     + RHH
Sbjct: 404  CG----KAFNHQSSLARHH 418



 Score =  101 bits (251), Expect = 7e-21
 Identities = 65/236 (27%), Positives = 94/236 (39%), Gaps = 23/236 (9%)

Query: 1443 VKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHT----GEKPYHCHLCP-----------Y 1487
            +KG    +L K T  A S    Q+I+   +IH     G  P +  L P           +
Sbjct: 172  IKGEIANQLEKSTSDASSVSTSQRISCRPQIHISNNYGNNPLNSSLLPQKQEVHMREKSF 231

Query: 1488 ACADPSR-------LKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPE 1540
             C +  +       L+ H   H  +++Y C  CG        L  H   HTG KPY+C E
Sbjct: 232  PCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKE 291

Query: 1541 CEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHR 1600
            C    +   +L  H    H   + + C +CGK F+    L  H   H+  KPY CN C +
Sbjct: 292  CGKSFSYKSSLTCHHRL-HTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGK 350

Query: 1601 AFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
            AF   + L  H   HT   P+ C++C         +  H R H  ++       GK
Sbjct: 351  AFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGK 406



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           ++++C  C  +  R   L +H+R      ++P  C ECG +F QQ  LS H
Sbjct: 537 KSYKCTVCNKVFMRNSVLAVHTRI--HTAKKPYKCNECGKAFNQQSHLSRH 585



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  + R+  AL +H    TG     +P  C ECG +F QQ  LS H
Sbjct: 313 KPYKCNECGKVFRQNSALVIHKAIHTG----EKPYKCNECGKAFNQQSHLSRH 361



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  +   ++ L  H R  C    +P  C ECG SF  +  L+ H
Sbjct: 257 KQYKCDVCGKLFNHKQYLACHRR--CHTGEKPYKCKECGKSFSYKSSLTCH 305


>gi|48717241 zinc finger protein 425 [Homo sapiens]
          Length = 752

 Score =  226 bits (576), Expect = 1e-58
 Identities = 151/549 (27%), Positives = 235/549 (42%), Gaps = 60/549 (10%)

Query: 1094 VLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLH 1153
            +L QK+   RF C  C  S   + +L THQ+          +H    P+  P       +
Sbjct: 239  LLCQKK---RFQCSECEKSYFLKGSLVTHQV----------VHTGQRPYPCPECDKTFRY 285

Query: 1154 QKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRY 1213
            +          RG RP   CG+CG    Q   + +H RL H G KP QCP CD     + 
Sbjct: 286  RANLKKHLCLHRGERPFC-CGECGRAFVQQCELTEHLRL-HSGEKPFQCPQCDRCFRLKR 343

Query: 1214 RLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDIT 1273
             ++ H ++H+G     C  C ++F   + L+ H+ R H +     C  C      +  + 
Sbjct: 344  GMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQ-RTHSEEKPFSCGECGRKFIYKIKLD 402

Query: 1274 RHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPA------------ 1321
             H+   H G   F+C +C   F  + +LK H L+   +     P                
Sbjct: 403  EHIR-VHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQ 461

Query: 1322 --ETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLE--CGACQEAFPSRLALDEHRR--- 1374
               + + P  C+ CG     P+ L  HTR    + E  CG C++ F  +  L +H +   
Sbjct: 462  RLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHT 521

Query: 1375 -QQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTC 1433
             ++ FS  C  C  + R R  L +H    H               +G+ P  CP CD + 
Sbjct: 522  TEKPFS--CAECGRSFRRRAHLTEH-TRLH---------------SGEEPFQCPECDKSF 563

Query: 1434 RHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPS 1493
              +  +  H + H   + + C +C  +  ++ ++T H R+H+GEKPY C  C        
Sbjct: 564  SWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKG 623

Query: 1494 RLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECE--YCTNRADAL 1551
             LK H+  H  ++ + C  CG       +L  H+  H+G KP+QCPEC+  YC     +L
Sbjct: 624  NLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIR--GSL 681

Query: 1552 RVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHH 1611
            +VH   +H   R F C +CGK F  +  L+ HL  HS  +P+ C+ C R+F +   L+ H
Sbjct: 682  KVHLY-KHSGERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTH 740

Query: 1612 ALTHTDRHP 1620
               H    P
Sbjct: 741  IAVHAKEKP 749



 Score =  210 bits (534), Expect = 1e-53
 Identities = 140/493 (28%), Positives = 204/493 (41%), Gaps = 36/493 (7%)

Query: 1168 RPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGR 1227
            +   QC +C  +      +  H+ + H G +P+ CP CD +   R  L+ H   H G   
Sbjct: 243  KKRFQCSECEKSYFLKGSLVTHQ-VVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERP 301

Query: 1228 IPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFA 1287
              C  C + F    +L  H LR+H       CP CD    L+  +  H+   H G   F 
Sbjct: 302  FCCGECGRAFVQQCELTEH-LRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQ-HSGKRPFH 359

Query: 1288 CSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT 1347
            C +C   FS + ALK H  R H E             E P  C  CG        L  H 
Sbjct: 360  CPECGRSFSRKAALKTHQ-RTHSE-------------EKPFSCGECGRKFIYKIKLDEHI 405

Query: 1348 RKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHR---CQLCDFAARERVGLVKHYLEQ 1402
            R         C  C ++F  + +L  H  Q H   R   C  C      R  +  H    
Sbjct: 406  RVHTGEKPFSCPECNKSFRLKRSLKAHGLQ-HIGKRPFQCPECSRGFFWRNAMRAHQRLH 464

Query: 1403 HEE------------TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTR 1450
             E+            T  +  A        Q    C  C  T   Q  L  H+K H   +
Sbjct: 465  SEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEK 524

Query: 1451 LYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLC 1510
             + C +C  S + R  +T H+R+H+GE+P+ C  C  + +  + +K+H R+H++E+ + C
Sbjct: 525  PFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFAC 584

Query: 1511 PECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQC 1570
             EC       +QL  H+  H+G KPYQCPECE        L+ H   +H   + F C  C
Sbjct: 585  GECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHL-LQHSGQKPFSCVMC 643

Query: 1571 GKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKA 1630
            GK+F  ++ L  H+R HS  KP+ C  C +++     L+ H   H+   PF C  C    
Sbjct: 644  GKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGF 703

Query: 1631 KQKFQVVKHVRRH 1643
             QK  +  H+  H
Sbjct: 704  LQKRSLKAHLCLH 716



 Score =  170 bits (431), Expect = 9e-42
 Identities = 121/434 (27%), Positives = 178/434 (41%), Gaps = 32/434 (7%)

Query: 165 CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLC 224
           C EC R F ++  L EHL LH  +   QCP C + F  K  +K HL +  G++  HCP C
Sbjct: 304 CGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHCPEC 363

Query: 225 HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPL 284
             S   + AL  H  +  E+        ++C  C  +F     L EH++ HT        
Sbjct: 364 GRSFSRKAALKTHQRTHSEE------KPFSCGECGRKFIYKIKLDEHIRVHTGEK----- 412

Query: 285 PLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPML---FATAEAMEAH---HK 338
           P  C +   S+        +K   + HG++ +  R   CP     F    AM AH   H 
Sbjct: 413 PFSCPECNKSFR-------LKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQRLHS 465

Query: 339 SHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHE 398
               F C  C    +       H +  H   +E  C  C   TF+  +      K+H  E
Sbjct: 466 EQKPFPCAECGKRFTRPSKLACHTRV-HDRQKEFPCGECK-KTFSQQSRLTQHLKVHTTE 523

Query: 399 KIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYM 458
           K   C EC  +   +  L  H  LH+GE+P +C  CD +    + +  H   H + K + 
Sbjct: 524 KPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFA 583

Query: 459 CTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVC 517
           C EC      +  L  H+R H+G+  YQC +C         L SH L+H G K   C +C
Sbjct: 584 CGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMC 643

Query: 518 AFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCAL 577
             +  ++Y L +H+  + H G     + C  C  +S   +  L     KH+  R F C  
Sbjct: 644 GKSFTQQYRLTEHI--RVHSGEKP--FQCPECD-KSYCIRGSLKVHLYKHSGERPFQCPE 698

Query: 578 CDYRTFSNTTLLFH 591
           C        +L  H
Sbjct: 699 CGKGFLQKRSLKAH 712



 Score =  166 bits (420), Expect = 2e-40
 Identities = 120/430 (27%), Positives = 171/430 (39%), Gaps = 39/430 (9%)

Query: 1223 TGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQG 1282
            TG     C  C + F     L  H+ R H K+     P    S   + ++ R      Q 
Sbjct: 185  TGPRCYSCYVCRKVFQVRRDLLKHK-RSHSKSQLCRYPKYKNSSRGKSELRRTQRLLCQ- 242

Query: 1283 TPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPAS 1342
               F CS+CE  +  + +L  H +                T + P  C  C       A+
Sbjct: 243  KKRFQCSECEKSYFLKGSLVTHQV--------------VHTGQRPYPCPECDKTFRYRAN 288

Query: 1343 LRGHT---RKQHPRLECGACQEAFPSRLALDEHRRQQHFSH--RCQLCDFAARERVGLVK 1397
            L+ H    R + P   CG C  AF  +  L EH R        +C  CD   R + G+  
Sbjct: 289  LKKHLCLHRGERPFC-CGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKV 347

Query: 1398 HYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDC 1457
            H L QH               +G+ P HCP C  +   +  L  H + H   + + C +C
Sbjct: 348  H-LTQH---------------SGKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGEC 391

Query: 1458 AYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKC 1517
                  + K+  H R+HTGEKP+ C  C  +      LK H   H  +R + CPEC    
Sbjct: 392  GRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGF 451

Query: 1518 KWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTR 1577
             W N ++ H   H+  KP+ C EC     R   L  H     R+ + F C +C K F  +
Sbjct: 452  FWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQ-KEFPCGECKKTFSQQ 510

Query: 1578 FLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVV 1637
              L  HL+ H+  KP+ C  C R+FR  A L  H   H+   PF C  C+     K  + 
Sbjct: 511  SRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMK 570

Query: 1638 KHVRRHHPDQ 1647
             H R H  ++
Sbjct: 571  FHQRMHRDEK 580



 Score =  164 bits (415), Expect = 7e-40
 Identities = 122/450 (27%), Positives = 184/450 (40%), Gaps = 49/450 (10%)

Query: 1091 GDTVLVQKQKGAR-FSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATA 1149
            G  V + +  G R F CP C  S  ++ AL+THQ            H    PF+      
Sbjct: 344  GMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQ----------RTHSEEKPFSCGECGR 393

Query: 1150 LRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFST 1209
              +++ +         G +P   C +C  + +  R ++ H  L+H G +P QCP C    
Sbjct: 394  KFIYKIKLDEHIRVHTGEKP-FSCPECNKSFRLKRSLKAHG-LQHIGKRPFQCPECSRGF 451

Query: 1210 TRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLR 1269
              R  + AHQ  H+     PC+ C + F   SKL  H  RVHD+     C  C  +   +
Sbjct: 452  FWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHT-RVHDRQKEFPCGECKKTFSQQ 510

Query: 1270 HDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLH 1329
              +T+H+   H     F+C++C   F     L +H  R H             + E P  
Sbjct: 511  SRLTQHLK-VHTTEKPFSCAECGRSFRRRAHLTEHT-RLH-------------SGEEPFQ 555

Query: 1330 CSRCGLLCPSPASLRGHTR--KQHPRLECGACQEAFPSRLALDEHRRQQHFS--HRCQLC 1385
            C  C       AS++ H R  +      CG C + +  +  L EH R       ++C  C
Sbjct: 556  CPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPEC 615

Query: 1386 DFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKG 1445
            +   R + G +K +L QH               +GQ P  C  C  +   Q  L  H++ 
Sbjct: 616  EKTFRLK-GNLKSHLLQH---------------SGQKPFSCVMCGKSFTQQYRLTEHIRV 659

Query: 1446 HGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEE 1505
            H G + ++C +C  S   R  +  H   H+GE+P+ C  C         LK H+ +H  E
Sbjct: 660  HSGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGE 719

Query: 1506 RKYLCPECGYKCKWVNQLKYHMTKHTGLKP 1535
            R + C ECG    +V  LK H+  H   KP
Sbjct: 720  RPFSCDECGRSFTYVGALKTHIAVHAKEKP 749



 Score =  162 bits (411), Expect = 2e-39
 Identities = 116/444 (26%), Positives = 180/444 (40%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           + + CPEC + F+ R +L +HL LH  +    C  C + F  + +L  HL    GEK   
Sbjct: 272 RPYPCPECDKTFRYRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQ 331

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           CP C      +  +  H+ + H     F+     CP C   F    ALK H ++H     
Sbjct: 332 CPQCDRCFRLKRGMKVHL-TQHSGKRPFH-----CPECGRSFSRKAALKTHQRTH----- 380

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
           +E  P  C + G  +    +    +H++   G +   C    C   F    +++AH   H
Sbjct: 381 SEEKPFSCGECGRKFIY--KIKLDEHIRVHTGEKPFSC--PECNKSFRLKRSLKAHGLQH 436

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F CP C      ++  R H++  H   +   C  C      P     H  ++H  
Sbjct: 437 IGKRPFQCPECSRGFFWRNAMRAHQRL-HSEQKPFPCAECGKRFTRPSKLACHT-RVHDR 494

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           +K   C EC    + +  L +H+ +HT EKP  C  C  + R  ++L++H   HS  + +
Sbjct: 495 QKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEPF 554

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C EC     WK  ++ H R H  +  + C +C        QL+ H   H G K   C  
Sbjct: 555 QCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPE 614

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C    + K  L+ H+  QH    P   + C  C  +S  +Q  L+     H+  + F C 
Sbjct: 615 CEKTFRLKGNLKSHLL-QHSGQKP---FSCVMCG-KSFTQQYRLTEHIRVHSGEKPFQCP 669

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            CD       +L  H  K  G  P
Sbjct: 670 ECDKSYCIRGSLKVHLYKHSGERP 693



 Score =  140 bits (353), Expect = 1e-32
 Identities = 95/340 (27%), Positives = 144/340 (42%), Gaps = 32/340 (9%)

Query: 1338 PSPASLRGHTRKQHPRLE---------CGACQEAFPSRLALDEHRRQQHFSHRCQL---- 1384
            P    LR   R+   RLE         C  C++ F  R  L +H+R    S  C+     
Sbjct: 165  PDKKDLRHKPRETPGRLEIPTGPRCYSCYVCRKVFQVRRDLLKHKRSHSKSQLCRYPKYK 224

Query: 1385 ------CDFAARERVGLVKHYLEQHE-ETSAAVAASDGDGDA---GQPPLHCPFCDFTCR 1434
                   +    +R+   K   +  E E S  +  S         GQ P  CP CD T R
Sbjct: 225  NSSRGKSELRRTQRLLCQKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFR 284

Query: 1435 HQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSR 1494
            ++  L  H+  H G R + C +C  +   + ++T H R+H+GEKP+ C  C         
Sbjct: 285  YRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRG 344

Query: 1495 LKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECE----YCTNRADA 1550
            +K H+  H  +R + CPECG        LK H   H+  KP+ C EC     Y     + 
Sbjct: 345  MKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEH 404

Query: 1551 LRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRH 1610
            +RVH   +      F C +C K+F+ +  L+ H  +H   +P+ C  C R F W   +R 
Sbjct: 405  IRVHTGEK-----PFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRA 459

Query: 1611 HALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADP 1650
            H   H+++ PF C  C  +  +  ++  H R H   +  P
Sbjct: 460  HQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFP 499



 Score =  137 bits (346), Expect = 7e-32
 Identities = 96/378 (25%), Positives = 149/378 (39%), Gaps = 38/378 (10%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T S  K   C EC R F  +  L EH+ +H  +    CP C K F  K  LK H L+ +G
Sbjct: 379 THSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIG 438

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNF-----------------------YSDT 252
           ++   CP C      RNA+  H   +H +   F                           
Sbjct: 439 KRPFQCPECSRGFFWRNAMRAHQR-LHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKE 497

Query: 253 YACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHG 312
           + C  C++ F     L +HLK HT        P  C + G S+    R    +H +   G
Sbjct: 498 FPCGECKKTFSQQSRLTQHLKVHTTEK-----PFSCAECGRSFRR--RAHLTEHTRLHSG 550

Query: 313 VRAVECRHHSCPMLFATAEAMEAH---HKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGS 369
               +C    C   F+   +M+ H   H+    F C  CD   +++    +H +  H G 
Sbjct: 551 EEPFQCPE--CDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRL-HSGE 607

Query: 370 EELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429
           +  +C  C          + H+   H+ +K   C  C  +   +  L  H+ +H+GEKP 
Sbjct: 608 KPYQCPECEKTFRLKGNLKSHL-LQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPF 666

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQ 489
           +C  CD +      L  H+  HS  + + C ECG     K  L+ H+  H+G+  + C++
Sbjct: 667 QCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDE 726

Query: 490 CSYRCHRADQLSSHKLRH 507
           C         L +H   H
Sbjct: 727 CGRSFTYVGALKTHIAVH 744



 Score =  121 bits (304), Expect = 5e-27
 Identities = 91/355 (25%), Positives = 144/355 (40%), Gaps = 35/355 (9%)

Query: 253 YACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHG 312
           Y+C VCR+ F++ + L +H +SH+ +              C Y  P  K   +   E   
Sbjct: 190 YSCYVCRKVFQVRRDLLKHKRSHSKSQL------------CRY--PKYKNSSRGKSELRR 235

Query: 313 VRAVECRHH-----SCPMLFATAEAMEAH---HKSHYAFHCPHCDFACSNKHLFRKHKKQ 364
            + + C+        C   +    ++  H   H     + CP CD     +   +KH   
Sbjct: 236 TQRLLCQKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCL 295

Query: 365 GHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHT 424
            H G     C  C  A        +H+ ++H+ EK  QCP+C+     KR +  H+  H+
Sbjct: 296 -HRGERPFCCGECGRAFVQQCELTEHL-RLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHS 353

Query: 425 GEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLR 484
           G++P  C  C  +    + L  H  THS  K + C ECG    +K  L  H+R H G+  
Sbjct: 354 GKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKP 413

Query: 485 YQCNQCSYRCHRADQLSSHKLRHQGK-SLMCEVCA--FACKRKYELQKHMASQHHPGTPA 541
           + C +C+        L +H L+H GK    C  C+  F  +      + + S+  P    
Sbjct: 414 FSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQRLHSEQKP---- 469

Query: 542 PLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAH 596
             +PC  C  +      +  H    H R +EF C  C  +TFS  + L    K H
Sbjct: 470 --FPCAECGKRFTRPSKLACHTRV-HDRQKEFPCGECK-KTFSQQSRLTQHLKVH 520



 Score =  109 bits (273), Expect = 2e-23
 Identities = 76/298 (25%), Positives = 122/298 (40%), Gaps = 20/298 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC + F + + L  H  +H       C  C+K F+ +S+L  HL     EK   
Sbjct: 468 KPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFS 527

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  S   R  L  H   +H        + + CP C + F    ++K H + H     
Sbjct: 528 CAECGRSFRRRAHLTEH-TRLHSG-----EEPFQCPECDKSFSWKASMKFHQRMHR---- 577

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
            +  P  C +  C      +    +HL+   G +  +C    C   F     +++H   H
Sbjct: 578 -DEKPFACGE--CDKTYTHQSQLTEHLRLHSGEKPYQCPE--CEKTFRLKGNLKSHLLQH 632

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                F C  C  + + ++   +H +  H G +  +C  C  +     + + H+ K H+ 
Sbjct: 633 SGQKPFSCVMCGKSFTQQYRLTEHIRV-HSGEKPFQCPECDKSYCIRGSLKVHLYK-HSG 690

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
           E+  QCPEC      KR L  H+ LH+GE+P  C+ C  +   V  L  H+  H+  K
Sbjct: 691 ERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKEK 748



 Score =  104 bits (259), Expect = 8e-22
 Identities = 71/268 (26%), Positives = 103/268 (38%), Gaps = 42/268 (15%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C EC R F++R HL EH  LH  +   QCP C K F+ K+ +K H      EK   
Sbjct: 524 KPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFA 583

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L  H+  +H          Y CP C + FRL   LK HL  H+    
Sbjct: 584 CGECDKTYTHQSQLTEHLR-LHSG-----EKPYQCPECEKTFRLKGNLKSHLLQHSGQK- 636

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C   G        K+F +  + T  +R                      H   
Sbjct: 637 ----PFSCVMCG--------KSFTQQYRLTEHIRV---------------------HSGE 663

Query: 341 YAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKI 400
             F CP CD +   +   + H  + H G    +C  C        + + H+  +H+ E+ 
Sbjct: 664 KPFQCPECDKSYCIRGSLKVHLYK-HSGERPFQCPECGKGFLQKRSLKAHLC-LHSGERP 721

Query: 401 HQCPECNFATAHKRVLIRHMLLHTGEKP 428
             C EC  +  +   L  H+ +H  EKP
Sbjct: 722 FSCDECGRSFTYVGALKTHIAVHAKEKP 749



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 99/440 (22%), Positives = 147/440 (33%), Gaps = 102/440 (23%)

Query: 834  RAFRCPHCPFITRREKALNLHSRTGCQ---------GRR-----------------EPLL 867
            R F CP C     R+ AL  H RT  +         GR+                 +P  
Sbjct: 356  RPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFS 415

Query: 868  CPECGASFKQQRGLSTHLLK-------KCPV---------LLRKNKGLPRPDSPIPLQP- 910
            CPEC  SF+ +R L  H L+       +CP           +R ++ L     P P    
Sbjct: 416  CPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAEC 475

Query: 911  ----VLPGTQASEDT--ESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVSGSPV 964
                  P   A      +  K  P   E +    + + L    +   TE+P +       
Sbjct: 476  GKRFTRPSKLACHTRVHDRQKEFPCG-ECKKTFSQQSRLTQHLKVHTTEKPFSCAE---- 530

Query: 965  PPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHRFEQG 1024
               G S    A   H  +         P + P+           + S   ++K H+    
Sbjct: 531  --CGRSFRRRA---HLTEHTRLHSGEEPFQCPECDK--------SFSWKASMKFHQ---- 573

Query: 1025 KFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPKNGST 1084
            + H +  PF C       +H ++     R   G++  P   P+                T
Sbjct: 574  RMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEK--PYQCPECE-------------KT 618

Query: 1085 ESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPF 1142
                G+  + L+Q      FSC  C  S  Q+  L  H IR      SGE    C  C  
Sbjct: 619  FRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEH-IR----VHSGEKPFQCPECDK 673

Query: 1143 TAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQC 1202
            +     +L++H  +         G RP  QC +CG    Q R ++ H  L H G +P  C
Sbjct: 674  SYCIRGSLKVHLYKH-------SGERP-FQCPECGKGFLQKRSLKAHLCL-HSGERPFSC 724

Query: 1203 PFCDFSTTRRYRLEAHQSRH 1222
              C  S T    L+ H + H
Sbjct: 725  DECGRSFTYVGALKTHIAVH 744



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + F+CP C    R ++ + +H  T   G+R P  CPECG SF ++  L TH
Sbjct: 328 KPFQCPQCDRCFRLKRGMKVHL-TQHSGKR-PFHCPECGRSFSRKAALKTH 376



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 823 RVQMVVIQGEGRAFRCPHCP--FITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRG 880
           +V +    GE R F+CP C   F+ +R    +L   +G      P  C ECG SF     
Sbjct: 682 KVHLYKHSGE-RPFQCPECGKGFLQKRSLKAHLCLHSG----ERPFSCDECGRSFTYVGA 736

Query: 881 LSTHL 885
           L TH+
Sbjct: 737 LKTHI 741



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 6/54 (11%)

Query: 834 RAFRCPHC--PFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHL 885
           R F C  C   F+ + E   +L   +G     +P  CP+C   F+ +RG+  HL
Sbjct: 300 RPFCCGECGRAFVQQCELTEHLRLHSG----EKPFQCPQCDRCFRLKRGMKVHL 349



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 829 IQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHL 885
           +  E + F C  C     R   L  H+R     R++   C EC  +F QQ  L+ HL
Sbjct: 463 LHSEQKPFPCAECGKRFTRPSKLACHTRV--HDRQKEFPCGECKKTFSQQSRLTQHL 517



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 820 LEGRVQMVVIQGEG-RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQ 878
           L+G ++  ++Q  G + F C  C     ++  L  H R       +P  CPEC  S+  +
Sbjct: 621 LKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRV--HSGEKPFQCPECDKSYCIR 678

Query: 879 RGLSTHLLK 887
             L  HL K
Sbjct: 679 GSLKVHLYK 687


>gi|40217792 zinc finger protein 585A [Homo sapiens]
          Length = 714

 Score =  226 bits (576), Expect = 1e-58
 Identities = 160/538 (29%), Positives = 230/538 (42%), Gaps = 52/538 (9%)

Query: 1132 SGELH--CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQH 1189
            +GE H  C+ C       + L++HQK          G R ++ C +CG    Q   +  H
Sbjct: 182  TGERHHECTDCGKAFTQKSTLKMHQKIH-------TGERSYI-CIECGQAFIQKTHLIAH 233

Query: 1190 RRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLR 1249
            RR+ H G KP++C  C  S   + +L+ HQ  HT +    C+   + F  NS L  H+ +
Sbjct: 234  RRI-HTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHK-K 291

Query: 1250 VHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRH 1309
            V  +  +  C  C  +   R ++  H    H G   + CS C   F+ ++AL  H  R H
Sbjct: 292  VQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYECSDCGKAFTQKSALTVHQ-RIH 349

Query: 1310 P---------------EPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR---KQH 1351
                            + A         T E P  C  CG L  S + L  H R    + 
Sbjct: 350  TGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEK 409

Query: 1352 PRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAA 1409
            P + C  C +AF +R  L  H++      S+ C  C  A  +R  L+ H   Q   T   
Sbjct: 410  PYM-CNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITH---QRIHT--- 462

Query: 1410 VAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITW 1469
                      G+ P  C  C      +  L+ H K H G R Y+C +C  +   +  +  
Sbjct: 463  ----------GEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIV 512

Query: 1470 HSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTK 1529
            H +IHTGEKPY C  C  A    S    H RIH  E+ Y C +CG      +QL  H   
Sbjct: 513  HQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPV 572

Query: 1530 HTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSE 1589
            HTG KPY C EC    +    L  HQ+T H   + ++C +CGK F+ +  L TH R H+ 
Sbjct: 573  HTGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECGKTFRQKSELITHHRIHTG 631

Query: 1590 AKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
             KPY C+ C ++F   + L+ H   HT   P+ C  C      +  + KH   H  D+
Sbjct: 632  EKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDK 689



 Score =  180 bits (457), Expect = 9e-45
 Identities = 141/493 (28%), Positives = 195/493 (39%), Gaps = 40/493 (8%)

Query: 1173 CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
            C +CG    Q      H++  H   KP +C  C  S  +   L  HQ  HTG     CS 
Sbjct: 105  CIECGKAFVQKPEFIIHQKT-HMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQ 163

Query: 1233 CPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCE 1292
            C + F  NS L +H  ++H     H C  C  +   +  +  H    H G  ++ C +C 
Sbjct: 164  CGKGFSYNSDLSIHE-KIHTGERHHECTDCGKAFTQKSTLKMH-QKIHTGERSYICIECG 221

Query: 1293 AQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP 1352
              F  +T L  H  R H             T E P  CS CG    S + L+ H R  H 
Sbjct: 222  QAFIQKTHLIAHR-RIH-------------TGEKPYECSNCGKSFISKSQLQVHQRV-HT 266

Query: 1353 RLECGACQE---AFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETS 1407
            R++   C E    F +   L  H++ Q    S  C  C  A   R  L+ H   Q   T 
Sbjct: 267  RVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIH---QRIHT- 322

Query: 1408 AAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKI 1467
                        G+ P  C  C      +  L  H + H G + Y C  C  +   +  +
Sbjct: 323  ------------GEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHL 370

Query: 1468 TWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHM 1527
              H  IHTGEKP+ C  C       S+L  H RIH  E+ Y+C +CG      + L  H 
Sbjct: 371  IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQ 430

Query: 1528 TKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKH 1587
              HTG K Y C +C     +   L  HQ   H   + + C  CGKAF  +  L  H + H
Sbjct: 431  KTHTGEKSYICSKCGKAFTQRSDLITHQRI-HTGEKPYECNTCGKAFTQKSHLNIHQKIH 489

Query: 1588 SEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
            +  + Y C+ C +AF   + L  H   HT   P+ C  C     +K   + H R H  ++
Sbjct: 490  TGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEK 549

Query: 1648 ADPNQGVGKDPTT 1660
                   GK  T+
Sbjct: 550  PYECSDCGKSFTS 562



 Score =  179 bits (455), Expect = 2e-44
 Identities = 130/457 (28%), Positives = 190/457 (41%), Gaps = 48/457 (10%)

Query: 1137 CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEG 1196
            C+ C       + L +HQ+          G +P+ +C DCG    Q   +  H+R+ H G
Sbjct: 301  CTECGKAFTYRSELIIHQRIH-------TGEKPY-ECSDCGKAFTQKSALTVHQRI-HTG 351

Query: 1197 VKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPT 1256
             K + C  C  +  ++  L AHQ  HTG     C  C + F + S+L +H+ R+H     
Sbjct: 352  EKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHK-RIHTGEKP 410

Query: 1257 HFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPA 1316
            + C  C  +   R ++  H  + H G  ++ CS+C   F+  + L  H  R H       
Sbjct: 411  YMCNKCGKAFTNRSNLITHQKT-HTGEKSYICSKCGKAFTQRSDLITHQ-RIH------- 461

Query: 1317 PGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP---RLECGACQEAFPSRLALDEHR 1373
                  T E P  C+ CG      + L  H +K H    + EC  C +AF  +  L  H+
Sbjct: 462  ------TGEKPYECNTCGKAFTQKSHLNIH-QKIHTGERQYECHECGKAFNQKSILIVHQ 514

Query: 1374 RQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFC--DF 1431
            +  H   +  +C    R  +        Q   T             G+ P  C  C   F
Sbjct: 515  KI-HTGEKPYVCTECGRAFIRKSNFITHQRIHT-------------GEKPYECSDCGKSF 560

Query: 1432 TCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACAD 1491
            T + QL++  H   H G + Y C +C  +   R  ++ H + HTGEKPY C  C      
Sbjct: 561  TSKSQLLV--HQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQ 618

Query: 1492 PSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADAL 1551
             S L  H RIH  E+ Y C +CG      +QL+ H   HTG KPY C EC         L
Sbjct: 619  KSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNL 678

Query: 1552 RVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHS 1588
              HQ T H   + + C  CGK F  + +   H   H+
Sbjct: 679  NKHQTT-HTGDKPYKCGICGKGFVQKSVFSVHQSSHA 714



 Score =  168 bits (425), Expect = 5e-41
 Identities = 120/435 (27%), Positives = 175/435 (40%), Gaps = 43/435 (9%)

Query: 157 ESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGE 216
           +S  K+ +C EC + F  R+ L+ H  +H  +   +C +C K FT KS L  H     GE
Sbjct: 293 QSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGE 352

Query: 217 KAHHCPLCHYSAVERNALNRHMA-----------------------SMHEDISNFYSDTY 253
           K++ C  C  + +++  L  H                          +H+ I       Y
Sbjct: 353 KSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG-EKPY 411

Query: 254 ACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGV 313
            C  C + F     L  H K+HT   +            C  A   R   I H +   G 
Sbjct: 412 MCNKCGKAFTNRSNLITHQKTHTGEKSY-------ICSKCGKAFTQRSDLITHQRIHTGE 464

Query: 314 RAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSE 370
           +  EC  ++C   F     +  H K H     + C  C  A + K +   H+K  H G +
Sbjct: 465 KPYEC--NTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQKI-HTGEK 521

Query: 371 ELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
              CT C  A      +  H  ++H  EK ++C +C  +   K  L+ H  +HTGEKP+ 
Sbjct: 522 PYVCTECGRAFIRKSNFITHQ-RIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C       S LSKH  TH+  K Y+C+ECG   + K  L  H R H G+  Y+C+ C
Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDC 640

Query: 491 SYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYC 549
                +  QL  H+  H G K  +C  C  A   +  L KH  +  H G     Y C  C
Sbjct: 641 GKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTT--HTGDKP--YKCGIC 696

Query: 550 SYQSRHKQAVLSHEN 564
                 K     H++
Sbjct: 697 GKGFVQKSVFSVHQS 711



 Score =  152 bits (385), Expect = 2e-36
 Identities = 131/502 (26%), Positives = 197/502 (39%), Gaps = 50/502 (9%)

Query: 102 REPSQEAGTPLPGQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFK 161
           ++ S +     PG++  E     K EK  TQK   K   K          V++G     K
Sbjct: 59  KQVSSQPQKMYPGEKAYE---CAKFEKIFTQKSQLKVHLK----------VLAGE----K 101

Query: 162 THMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHC 221
            ++C EC + F ++   + H   H  +   +C  C K F   S L  H     GEK + C
Sbjct: 102 LYVCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYEC 161

Query: 222 PLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAA 281
             C       + L     S+HE I       + C  C + F     LK H K HT   + 
Sbjct: 162 SQCGKGFSYNSDL-----SIHEKIHTGERH-HECTDCGKAFTQKSTLKMHQKIHTGERS- 214

Query: 282 EPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHY 341
                 C +  C  A   +   I H +   G +  EC +  C   F +   ++ H + H 
Sbjct: 215 ----YICIE--CGQAFIQKTHLIAHRRIHTGEKPYECSN--CGKSFISKSQLQVHQRVHT 266

Query: 342 A---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHV---GKMH 395
               + C       SN      HKK        + CT C  A      Y+  +    ++H
Sbjct: 267 RVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSI-CTECGKA----FTYRSELIIHQRIH 321

Query: 396 AHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
             EK ++C +C  A   K  L  H  +HTGEK + C  C       ++L  H + H+  K
Sbjct: 322 TGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEK 381

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMC 514
            + C  CG +   K  L VH R H G+  Y CN+C         L +H+  H G KS +C
Sbjct: 382 PHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYIC 441

Query: 515 EVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
             C  A  ++ +L  H   + H G     Y C+ C      K  +  H+   HT  R++ 
Sbjct: 442 SKCGKAFTQRSDLITH--QRIHTGEKP--YECNTCGKAFTQKSHLNIHQKI-HTGERQYE 496

Query: 575 CALCDYRTFSNTTLLFHKRKAH 596
           C  C  + F+  ++L   +K H
Sbjct: 497 CHECG-KAFNQKSILIVHQKIH 517



 Score =  145 bits (366), Expect = 3e-34
 Identities = 113/425 (26%), Positives = 161/425 (37%), Gaps = 65/425 (15%)

Query: 1280 HQGTPAFACSQCEAQFSSETALKQHAL--------------RRHPEPAQPAPGSPAETTE 1325
            + G  A+ C++ E  F+ ++ LK H                +   +  +          E
Sbjct: 69   YPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMRE 128

Query: 1326 GPLHCSRCGLLCPSPASLRGHTR--KQHPRLECGACQEAFP--SRLALDE--HRRQQHFS 1379
             P  C+ CG      +SL  H R        EC  C + F   S L++ E  H  ++H  
Sbjct: 129  KPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH-- 186

Query: 1380 HRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDG-------------DAGQPPLHC 1426
            H C  C  A  ++  L  H  + H    + +    G                 G+ P  C
Sbjct: 187  HECTDCGKAFTQKSTLKMHQ-KIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYEC 245

Query: 1427 PFC--DFTCRHQLVLDH--------------------------HVKGHGGTRLYKCTDCA 1458
              C   F  + QL +                            H K     +   CT+C 
Sbjct: 246  SNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECG 305

Query: 1459 YSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCK 1518
             +   R ++  H RIHTGEKPY C  C  A    S L  H RIH  E+ Y+C +CG    
Sbjct: 306  KAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFI 365

Query: 1519 WVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRF 1578
                L  H   HTG KP++C  C         L VH+   H   + +MC +CGKAF  R 
Sbjct: 366  QKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRI-HTGEKPYMCNKCGKAFTNRS 424

Query: 1579 LLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVK 1638
             L TH + H+  K Y+C+ C +AF   + L  H   HT   P+ C  C     QK  +  
Sbjct: 425  NLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNI 484

Query: 1639 HVRRH 1643
            H + H
Sbjct: 485  HQKIH 489



 Score =  145 bits (366), Expect = 3e-34
 Identities = 116/431 (26%), Positives = 166/431 (38%), Gaps = 48/431 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH--CSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  Q+ AL  HQ        +GE    C  C         L  HQ       
Sbjct: 327  YECSDCGKAFTQKSALTVHQ-----RIHTGEKSYICMKCGLAFIQKAHLIAHQIIH---- 377

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH +CG CG        +  H+R+ H G KP+ C  C  + T R  L  HQ  
Sbjct: 378  ---TGEKPH-KCGHCGKLFTSKSQLHVHKRI-HTGEKPYMCNKCGKAFTNRSNLITHQKT 432

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F   S L  H+ R+H     + C  C  +   +  +  H    H 
Sbjct: 433  HTGEKSYICSKCGKAFTQRSDLITHQ-RIHTGEKPYECNTCGKAFTQKSHLNIH-QKIHT 490

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C   F+ ++ L  H                  T E P  C+ CG      +
Sbjct: 491  GERQYECHECGKAFNQKSILIVH--------------QKIHTGEKPYVCTECGRAFIRKS 536

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHY 1399
            +   H R        EC  C ++F S+  L  H+   H   +  +C    +   G  +  
Sbjct: 537  NFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQ-PVHTGEKPYVCAECGKAFSG--RSN 593

Query: 1400 LEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAY 1459
            L +H++T             G+ P  C  C  T R +  L  H + H G + Y+C+DC  
Sbjct: 594  LSKHQKTHT-----------GEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGK 642

Query: 1460 STKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            S   + ++  H RIHTGEKPY C  C  A  D S L  H   H  ++ Y C  CG     
Sbjct: 643  SFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQ 702

Query: 1520 VNQLKYHMTKH 1530
             +    H + H
Sbjct: 703  KSVFSVHQSSH 713



 Score =  140 bits (353), Expect = 1e-32
 Identities = 97/323 (30%), Positives = 134/323 (41%), Gaps = 20/323 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K +MC +C + F  R++L+ H   H  + S  C  C K FT +S L TH     GEK + 
Sbjct: 409 KPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYE 468

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ LN H   +H          Y C  C + F     L  H K HT    
Sbjct: 469 CNTCGKAFTQKSHLNIHQ-KIHTG-----ERQYECHECGKAFNQKSILIVHQKIHTGEK- 521

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P  C +  C  A   +  FI H +   G +  EC    C   F +   +  H   H
Sbjct: 522 ----PYVCTE--CGRAFIRKSNFITHQRIHTGEKPYECS--DCGKSFTSKSQLLVHQPVH 573

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +    KH+K  H G +   C+ C   TF   +      ++H  
Sbjct: 574 TGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECG-KTFRQKSELITHHRIHTG 631

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  +   K  L  H  +HTGEKP+ C  C     D S L+KH  TH+  K Y
Sbjct: 632 EKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPY 691

Query: 458 MCTECGYVTKWKHYLRVHMRKHA 480
            C  CG     K    VH   HA
Sbjct: 692 KCGICGKGFVQKSVFSVHQSSHA 714



 Score =  139 bits (351), Expect = 2e-32
 Identities = 104/377 (27%), Positives = 144/377 (38%), Gaps = 46/377 (12%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K+++C +C   F ++ HL+ H  +H  +   +C +C K FTSKS+L  H     GEK + 
Sbjct: 353 KSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYM 412

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R+ L  H  +   + S      Y C  C + F     L  H + HT    
Sbjct: 413 CNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHTGEK- 465

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A   +     H K   G R  EC  H C   F     +  H K H
Sbjct: 466 ----PYEC--NTCGKAFTQKSHLNIHQKIHTGERQYEC--HECGKAFNQKSILIVHQKIH 517

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQD--HVG- 392
                + C  C  A   K  F  H++  H G +   C+ C   F + + +      H G 
Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRI-HTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE 576

Query: 393 ----------------------KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
                                 K H  EK + C EC      K  LI H  +HTGEKP++
Sbjct: 577 KPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYE 636

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C  +    S L  H   H+  K Y+C ECG     +  L  H   H GD  Y+C  C
Sbjct: 637 CSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGIC 696

Query: 491 SYRCHRADQLSSHKLRH 507
                +    S H+  H
Sbjct: 697 GKGFVQKSVFSVHQSSH 713



 Score =  136 bits (343), Expect = 2e-31
 Identities = 101/363 (27%), Positives = 154/363 (42%), Gaps = 32/363 (8%)

Query: 1311 EPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR-----KQHPRLECGACQEAFPS 1365
            +P +  PG  A        C++   +    + L+ H +     K +  +ECG      P 
Sbjct: 64   QPQKMYPGEKA------YECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPE 117

Query: 1366 RLALDE-HRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPL 1424
             +   + H R++ F  +C  C  +  +   L +H   Q   T             G+   
Sbjct: 118  FIIHQKTHMREKPF--KCNECGKSFFQVSSLFRH---QRIHT-------------GEKLY 159

Query: 1425 HCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHL 1484
             C  C     +   L  H K H G R ++CTDC  +   +  +  H +IHTGE+ Y C  
Sbjct: 160  ECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIE 219

Query: 1485 CPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYC 1544
            C  A    + L  H RIH  E+ Y C  CG      +QL+ H   HT +KPY C E    
Sbjct: 220  CGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKV 279

Query: 1545 TNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRW 1604
             +    L  H++ + RE ++ +C +CGKAF  R  L  H R H+  KPY C+ C +AF  
Sbjct: 280  FSNNSNLVTHKKVQSRE-KSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQ 338

Query: 1605 AAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPT-V 1663
             + L  H   HT    + C  C     QK  ++ H   H  ++       GK  T+ + +
Sbjct: 339  KSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398

Query: 1664 HLH 1666
            H+H
Sbjct: 399  HVH 401



 Score =  135 bits (340), Expect = 3e-31
 Identities = 121/508 (23%), Positives = 184/508 (36%), Gaps = 82/508 (16%)

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHY 226
           +C++    +    +   ++  + + +C   +K FT KS+LK HL    GEK + C  C  
Sbjct: 51  QCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGK 110

Query: 227 SAVERNALNRHMAS-MHE-------------DISNFY--------SDTYACPVCREEFRL 264
           + V++     H  + M E              +S+ +           Y C  C + F  
Sbjct: 111 AFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSY 170

Query: 265 SQALKEHLKSHT----------AAAAAEPLPLRCFQE-----------GCSYAAPDRKAF 303
           +  L  H K HT            A  +   L+  Q+            C  A   +   
Sbjct: 171 NSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHL 230

Query: 304 IKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH---YAFHCPHCDFACSNKHLFRK 360
           I H +   G +  EC   +C   F +   ++ H + H     + C       SN      
Sbjct: 231 IAHRRIHTGEKPYEC--SNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVT 288

Query: 361 HKK---------------------------QGHPGSEELRCTFCPFATFNPVAYQDHVGK 393
           HKK                           + H G +   C+ C  A     A   H  +
Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVH-QR 347

Query: 394 MHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSN 453
           +H  EK + C +C  A   K  LI H ++HTGEKPHKC  C       S L  H   H+ 
Sbjct: 348 IHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG 407

Query: 454 TKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSL 512
            K YMC +CG     +  L  H + H G+  Y C++C     +   L +H+  H G K  
Sbjct: 408 EKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPY 467

Query: 513 MCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLRE 572
            C  C  A  +K  L  H   + H G     Y CH C      K  ++ H+   HT  + 
Sbjct: 468 ECNTCGKAFTQKSHLNIH--QKIHTGERQ--YECHECGKAFNQKSILIVHQKI-HTGEKP 522

Query: 573 FHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           + C  C       +  + H+R   G  P
Sbjct: 523 YVCTECGRAFIRKSNFITHQRIHTGEKP 550



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 1/209 (0%)

Query: 1448 GTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERK 1507
            G +L+    C      +Q  +   +++ GEK Y C          S+LK H+++   E+ 
Sbjct: 43   GEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKL 102

Query: 1508 YLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMC 1567
            Y+C ECG       +   H   H   KP++C EC     +  +L  HQ   H   + + C
Sbjct: 103  YVCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRI-HTGEKLYEC 161

Query: 1568 EQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCN 1627
             QCGK F     L  H + H+  + + C  C +AF   + L+ H   HT    + C  C 
Sbjct: 162  SQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECG 221

Query: 1628 YKAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
                QK  ++ H R H  ++       GK
Sbjct: 222  QAFIQKTHLIAHRRIHTGEKPYECSNCGK 250



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 50/208 (24%), Positives = 81/208 (38%), Gaps = 14/208 (6%)

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK+    +C    ++K+V  +   ++ GEK ++C   +      S L  H+   +  K Y
Sbjct: 44  EKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLY 103

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLM-CEV 516
           +C ECG     K    +H + H  +  ++CN+C     +   L  H+  H G+ L  C  
Sbjct: 104 VCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQ 163

Query: 517 CAFACKRKYEL----QKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLRE 572
           C        +L    + H   +HH         C  C      K  +  H+   HT  R 
Sbjct: 164 CGKGFSYNSDLSIHEKIHTGERHH--------ECTDCGKAFTQKSTLKMHQKI-HTGERS 214

Query: 573 FHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           + C  C       T L+ H+R   G  P
Sbjct: 215 YICIECGQAFIQKTHLIAHRRIHTGEKP 242



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    +  +C HC  +   +  L++H R  TG     +P +C +CG +F  +  L TH
Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG----EKPYMCNKCGKAFTNRSNLITH 429



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           V   V  GE + + C  C         L+ H +T      +P +C ECG +F+Q+  L T
Sbjct: 568 VHQPVHTGE-KPYVCAECGKAFSGRSNLSKHQKT--HTGEKPYICSECGKTFRQKSELIT 624

Query: 884 H 884
           H
Sbjct: 625 H 625


>gi|22749331 zinc finger protein 585A [Homo sapiens]
          Length = 714

 Score =  226 bits (576), Expect = 1e-58
 Identities = 160/538 (29%), Positives = 230/538 (42%), Gaps = 52/538 (9%)

Query: 1132 SGELH--CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQH 1189
            +GE H  C+ C       + L++HQK          G R ++ C +CG    Q   +  H
Sbjct: 182  TGERHHECTDCGKAFTQKSTLKMHQKIH-------TGERSYI-CIECGQAFIQKTHLIAH 233

Query: 1190 RRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLR 1249
            RR+ H G KP++C  C  S   + +L+ HQ  HT +    C+   + F  NS L  H+ +
Sbjct: 234  RRI-HTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHK-K 291

Query: 1250 VHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRH 1309
            V  +  +  C  C  +   R ++  H    H G   + CS C   F+ ++AL  H  R H
Sbjct: 292  VQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYECSDCGKAFTQKSALTVHQ-RIH 349

Query: 1310 P---------------EPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR---KQH 1351
                            + A         T E P  C  CG L  S + L  H R    + 
Sbjct: 350  TGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEK 409

Query: 1352 PRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAA 1409
            P + C  C +AF +R  L  H++      S+ C  C  A  +R  L+ H   Q   T   
Sbjct: 410  PYM-CNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITH---QRIHT--- 462

Query: 1410 VAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITW 1469
                      G+ P  C  C      +  L+ H K H G R Y+C +C  +   +  +  
Sbjct: 463  ----------GEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIV 512

Query: 1470 HSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTK 1529
            H +IHTGEKPY C  C  A    S    H RIH  E+ Y C +CG      +QL  H   
Sbjct: 513  HQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPV 572

Query: 1530 HTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSE 1589
            HTG KPY C EC    +    L  HQ+T H   + ++C +CGK F+ +  L TH R H+ 
Sbjct: 573  HTGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECGKTFRQKSELITHHRIHTG 631

Query: 1590 AKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
             KPY C+ C ++F   + L+ H   HT   P+ C  C      +  + KH   H  D+
Sbjct: 632  EKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDK 689



 Score =  180 bits (457), Expect = 9e-45
 Identities = 141/493 (28%), Positives = 195/493 (39%), Gaps = 40/493 (8%)

Query: 1173 CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
            C +CG    Q      H++  H   KP +C  C  S  +   L  HQ  HTG     CS 
Sbjct: 105  CIECGKAFVQKPEFIIHQKT-HMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQ 163

Query: 1233 CPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCE 1292
            C + F  NS L +H  ++H     H C  C  +   +  +  H    H G  ++ C +C 
Sbjct: 164  CGKGFSYNSDLSIHE-KIHTGERHHECTDCGKAFTQKSTLKMH-QKIHTGERSYICIECG 221

Query: 1293 AQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP 1352
              F  +T L  H  R H             T E P  CS CG    S + L+ H R  H 
Sbjct: 222  QAFIQKTHLIAHR-RIH-------------TGEKPYECSNCGKSFISKSQLQVHQRV-HT 266

Query: 1353 RLECGACQE---AFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETS 1407
            R++   C E    F +   L  H++ Q    S  C  C  A   R  L+ H   Q   T 
Sbjct: 267  RVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIH---QRIHT- 322

Query: 1408 AAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKI 1467
                        G+ P  C  C      +  L  H + H G + Y C  C  +   +  +
Sbjct: 323  ------------GEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHL 370

Query: 1468 TWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHM 1527
              H  IHTGEKP+ C  C       S+L  H RIH  E+ Y+C +CG      + L  H 
Sbjct: 371  IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQ 430

Query: 1528 TKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKH 1587
              HTG K Y C +C     +   L  HQ   H   + + C  CGKAF  +  L  H + H
Sbjct: 431  KTHTGEKSYICSKCGKAFTQRSDLITHQRI-HTGEKPYECNTCGKAFTQKSHLNIHQKIH 489

Query: 1588 SEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
            +  + Y C+ C +AF   + L  H   HT   P+ C  C     +K   + H R H  ++
Sbjct: 490  TGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEK 549

Query: 1648 ADPNQGVGKDPTT 1660
                   GK  T+
Sbjct: 550  PYECSDCGKSFTS 562



 Score =  179 bits (455), Expect = 2e-44
 Identities = 130/457 (28%), Positives = 190/457 (41%), Gaps = 48/457 (10%)

Query: 1137 CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEG 1196
            C+ C       + L +HQ+          G +P+ +C DCG    Q   +  H+R+ H G
Sbjct: 301  CTECGKAFTYRSELIIHQRIH-------TGEKPY-ECSDCGKAFTQKSALTVHQRI-HTG 351

Query: 1197 VKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPT 1256
             K + C  C  +  ++  L AHQ  HTG     C  C + F + S+L +H+ R+H     
Sbjct: 352  EKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHK-RIHTGEKP 410

Query: 1257 HFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPA 1316
            + C  C  +   R ++  H  + H G  ++ CS+C   F+  + L  H  R H       
Sbjct: 411  YMCNKCGKAFTNRSNLITHQKT-HTGEKSYICSKCGKAFTQRSDLITHQ-RIH------- 461

Query: 1317 PGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP---RLECGACQEAFPSRLALDEHR 1373
                  T E P  C+ CG      + L  H +K H    + EC  C +AF  +  L  H+
Sbjct: 462  ------TGEKPYECNTCGKAFTQKSHLNIH-QKIHTGERQYECHECGKAFNQKSILIVHQ 514

Query: 1374 RQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFC--DF 1431
            +  H   +  +C    R  +        Q   T             G+ P  C  C   F
Sbjct: 515  KI-HTGEKPYVCTECGRAFIRKSNFITHQRIHT-------------GEKPYECSDCGKSF 560

Query: 1432 TCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACAD 1491
            T + QL++  H   H G + Y C +C  +   R  ++ H + HTGEKPY C  C      
Sbjct: 561  TSKSQLLV--HQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQ 618

Query: 1492 PSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADAL 1551
             S L  H RIH  E+ Y C +CG      +QL+ H   HTG KPY C EC         L
Sbjct: 619  KSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNL 678

Query: 1552 RVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHS 1588
              HQ T H   + + C  CGK F  + +   H   H+
Sbjct: 679  NKHQTT-HTGDKPYKCGICGKGFVQKSVFSVHQSSHA 714



 Score =  168 bits (425), Expect = 5e-41
 Identities = 120/435 (27%), Positives = 175/435 (40%), Gaps = 43/435 (9%)

Query: 157 ESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGE 216
           +S  K+ +C EC + F  R+ L+ H  +H  +   +C +C K FT KS L  H     GE
Sbjct: 293 QSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGE 352

Query: 217 KAHHCPLCHYSAVERNALNRHMA-----------------------SMHEDISNFYSDTY 253
           K++ C  C  + +++  L  H                          +H+ I       Y
Sbjct: 353 KSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG-EKPY 411

Query: 254 ACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGV 313
            C  C + F     L  H K+HT   +            C  A   R   I H +   G 
Sbjct: 412 MCNKCGKAFTNRSNLITHQKTHTGEKSY-------ICSKCGKAFTQRSDLITHQRIHTGE 464

Query: 314 RAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSE 370
           +  EC  ++C   F     +  H K H     + C  C  A + K +   H+K  H G +
Sbjct: 465 KPYEC--NTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQKI-HTGEK 521

Query: 371 ELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
              CT C  A      +  H  ++H  EK ++C +C  +   K  L+ H  +HTGEKP+ 
Sbjct: 522 PYVCTECGRAFIRKSNFITHQ-RIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C       S LSKH  TH+  K Y+C+ECG   + K  L  H R H G+  Y+C+ C
Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDC 640

Query: 491 SYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYC 549
                +  QL  H+  H G K  +C  C  A   +  L KH  +  H G     Y C  C
Sbjct: 641 GKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTT--HTGDKP--YKCGIC 696

Query: 550 SYQSRHKQAVLSHEN 564
                 K     H++
Sbjct: 697 GKGFVQKSVFSVHQS 711



 Score =  152 bits (385), Expect = 2e-36
 Identities = 131/502 (26%), Positives = 197/502 (39%), Gaps = 50/502 (9%)

Query: 102 REPSQEAGTPLPGQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFK 161
           ++ S +     PG++  E     K EK  TQK   K   K          V++G     K
Sbjct: 59  KQVSSQPQKMYPGEKAYE---CAKFEKIFTQKSQLKVHLK----------VLAGE----K 101

Query: 162 THMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHC 221
            ++C EC + F ++   + H   H  +   +C  C K F   S L  H     GEK + C
Sbjct: 102 LYVCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYEC 161

Query: 222 PLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAA 281
             C       + L     S+HE I       + C  C + F     LK H K HT   + 
Sbjct: 162 SQCGKGFSYNSDL-----SIHEKIHTGERH-HECTDCGKAFTQKSTLKMHQKIHTGERS- 214

Query: 282 EPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHY 341
                 C +  C  A   +   I H +   G +  EC +  C   F +   ++ H + H 
Sbjct: 215 ----YICIE--CGQAFIQKTHLIAHRRIHTGEKPYECSN--CGKSFISKSQLQVHQRVHT 266

Query: 342 A---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHV---GKMH 395
               + C       SN      HKK        + CT C  A      Y+  +    ++H
Sbjct: 267 RVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSI-CTECGKA----FTYRSELIIHQRIH 321

Query: 396 AHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
             EK ++C +C  A   K  L  H  +HTGEK + C  C       ++L  H + H+  K
Sbjct: 322 TGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEK 381

Query: 456 DYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMC 514
            + C  CG +   K  L VH R H G+  Y CN+C         L +H+  H G KS +C
Sbjct: 382 PHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYIC 441

Query: 515 EVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFH 574
             C  A  ++ +L  H   + H G     Y C+ C      K  +  H+   HT  R++ 
Sbjct: 442 SKCGKAFTQRSDLITH--QRIHTGEKP--YECNTCGKAFTQKSHLNIHQKI-HTGERQYE 496

Query: 575 CALCDYRTFSNTTLLFHKRKAH 596
           C  C  + F+  ++L   +K H
Sbjct: 497 CHECG-KAFNQKSILIVHQKIH 517



 Score =  145 bits (366), Expect = 3e-34
 Identities = 113/425 (26%), Positives = 161/425 (37%), Gaps = 65/425 (15%)

Query: 1280 HQGTPAFACSQCEAQFSSETALKQHAL--------------RRHPEPAQPAPGSPAETTE 1325
            + G  A+ C++ E  F+ ++ LK H                +   +  +          E
Sbjct: 69   YPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMRE 128

Query: 1326 GPLHCSRCGLLCPSPASLRGHTR--KQHPRLECGACQEAFP--SRLALDE--HRRQQHFS 1379
             P  C+ CG      +SL  H R        EC  C + F   S L++ E  H  ++H  
Sbjct: 129  KPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH-- 186

Query: 1380 HRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDG-------------DAGQPPLHC 1426
            H C  C  A  ++  L  H  + H    + +    G                 G+ P  C
Sbjct: 187  HECTDCGKAFTQKSTLKMHQ-KIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYEC 245

Query: 1427 PFC--DFTCRHQLVLDH--------------------------HVKGHGGTRLYKCTDCA 1458
              C   F  + QL +                            H K     +   CT+C 
Sbjct: 246  SNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECG 305

Query: 1459 YSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCK 1518
             +   R ++  H RIHTGEKPY C  C  A    S L  H RIH  E+ Y+C +CG    
Sbjct: 306  KAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFI 365

Query: 1519 WVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRF 1578
                L  H   HTG KP++C  C         L VH+   H   + +MC +CGKAF  R 
Sbjct: 366  QKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRI-HTGEKPYMCNKCGKAFTNRS 424

Query: 1579 LLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVK 1638
             L TH + H+  K Y+C+ C +AF   + L  H   HT   P+ C  C     QK  +  
Sbjct: 425  NLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNI 484

Query: 1639 HVRRH 1643
            H + H
Sbjct: 485  HQKIH 489



 Score =  145 bits (366), Expect = 3e-34
 Identities = 116/431 (26%), Positives = 166/431 (38%), Gaps = 48/431 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH--CSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  Q+ AL  HQ        +GE    C  C         L  HQ       
Sbjct: 327  YECSDCGKAFTQKSALTVHQ-----RIHTGEKSYICMKCGLAFIQKAHLIAHQIIH---- 377

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +PH +CG CG        +  H+R+ H G KP+ C  C  + T R  L  HQ  
Sbjct: 378  ---TGEKPH-KCGHCGKLFTSKSQLHVHKRI-HTGEKPYMCNKCGKAFTNRSNLITHQKT 432

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F   S L  H+ R+H     + C  C  +   +  +  H    H 
Sbjct: 433  HTGEKSYICSKCGKAFTQRSDLITHQ-RIHTGEKPYECNTCGKAFTQKSHLNIH-QKIHT 490

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C   F+ ++ L  H                  T E P  C+ CG      +
Sbjct: 491  GERQYECHECGKAFNQKSILIVH--------------QKIHTGEKPYVCTECGRAFIRKS 536

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHY 1399
            +   H R        EC  C ++F S+  L  H+   H   +  +C    +   G  +  
Sbjct: 537  NFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQ-PVHTGEKPYVCAECGKAFSG--RSN 593

Query: 1400 LEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAY 1459
            L +H++T             G+ P  C  C  T R +  L  H + H G + Y+C+DC  
Sbjct: 594  LSKHQKTHT-----------GEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGK 642

Query: 1460 STKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            S   + ++  H RIHTGEKPY C  C  A  D S L  H   H  ++ Y C  CG     
Sbjct: 643  SFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQ 702

Query: 1520 VNQLKYHMTKH 1530
             +    H + H
Sbjct: 703  KSVFSVHQSSH 713



 Score =  140 bits (353), Expect = 1e-32
 Identities = 97/323 (30%), Positives = 134/323 (41%), Gaps = 20/323 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K +MC +C + F  R++L+ H   H  + S  C  C K FT +S L TH     GEK + 
Sbjct: 409 KPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYE 468

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ LN H   +H          Y C  C + F     L  H K HT    
Sbjct: 469 CNTCGKAFTQKSHLNIHQ-KIHTG-----ERQYECHECGKAFNQKSILIVHQKIHTGEK- 521

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P  C +  C  A   +  FI H +   G +  EC    C   F +   +  H   H
Sbjct: 522 ----PYVCTE--CGRAFIRKSNFITHQRIHTGEKPYECS--DCGKSFTSKSQLLVHQPVH 573

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +    KH+K  H G +   C+ C   TF   +      ++H  
Sbjct: 574 TGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECG-KTFRQKSELITHHRIHTG 631

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  +   K  L  H  +HTGEKP+ C  C     D S L+KH  TH+  K Y
Sbjct: 632 EKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPY 691

Query: 458 MCTECGYVTKWKHYLRVHMRKHA 480
            C  CG     K    VH   HA
Sbjct: 692 KCGICGKGFVQKSVFSVHQSSHA 714



 Score =  139 bits (351), Expect = 2e-32
 Identities = 104/377 (27%), Positives = 144/377 (38%), Gaps = 46/377 (12%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K+++C +C   F ++ HL+ H  +H  +   +C +C K FTSKS+L  H     GEK + 
Sbjct: 353 KSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYM 412

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R+ L  H  +   + S      Y C  C + F     L  H + HT    
Sbjct: 413 CNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHTGEK- 465

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A   +     H K   G R  EC  H C   F     +  H K H
Sbjct: 466 ----PYEC--NTCGKAFTQKSHLNIHQKIHTGERQYEC--HECGKAFNQKSILIVHQKIH 517

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQD--HVG- 392
                + C  C  A   K  F  H++  H G +   C+ C   F + + +      H G 
Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRI-HTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE 576

Query: 393 ----------------------KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
                                 K H  EK + C EC      K  LI H  +HTGEKP++
Sbjct: 577 KPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYE 636

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C  +    S L  H   H+  K Y+C ECG     +  L  H   H GD  Y+C  C
Sbjct: 637 CSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGIC 696

Query: 491 SYRCHRADQLSSHKLRH 507
                +    S H+  H
Sbjct: 697 GKGFVQKSVFSVHQSSH 713



 Score =  136 bits (343), Expect = 2e-31
 Identities = 101/363 (27%), Positives = 154/363 (42%), Gaps = 32/363 (8%)

Query: 1311 EPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR-----KQHPRLECGACQEAFPS 1365
            +P +  PG  A        C++   +    + L+ H +     K +  +ECG      P 
Sbjct: 64   QPQKMYPGEKA------YECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPE 117

Query: 1366 RLALDE-HRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPL 1424
             +   + H R++ F  +C  C  +  +   L +H   Q   T             G+   
Sbjct: 118  FIIHQKTHMREKPF--KCNECGKSFFQVSSLFRH---QRIHT-------------GEKLY 159

Query: 1425 HCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHL 1484
             C  C     +   L  H K H G R ++CTDC  +   +  +  H +IHTGE+ Y C  
Sbjct: 160  ECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIE 219

Query: 1485 CPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYC 1544
            C  A    + L  H RIH  E+ Y C  CG      +QL+ H   HT +KPY C E    
Sbjct: 220  CGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKV 279

Query: 1545 TNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRW 1604
             +    L  H++ + RE ++ +C +CGKAF  R  L  H R H+  KPY C+ C +AF  
Sbjct: 280  FSNNSNLVTHKKVQSRE-KSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQ 338

Query: 1605 AAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPT-V 1663
             + L  H   HT    + C  C     QK  ++ H   H  ++       GK  T+ + +
Sbjct: 339  KSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398

Query: 1664 HLH 1666
            H+H
Sbjct: 399  HVH 401



 Score =  135 bits (340), Expect = 3e-31
 Identities = 121/508 (23%), Positives = 184/508 (36%), Gaps = 82/508 (16%)

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHY 226
           +C++    +    +   ++  + + +C   +K FT KS+LK HL    GEK + C  C  
Sbjct: 51  QCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGK 110

Query: 227 SAVERNALNRHMAS-MHE-------------DISNFY--------SDTYACPVCREEFRL 264
           + V++     H  + M E              +S+ +           Y C  C + F  
Sbjct: 111 AFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSY 170

Query: 265 SQALKEHLKSHT----------AAAAAEPLPLRCFQE-----------GCSYAAPDRKAF 303
           +  L  H K HT            A  +   L+  Q+            C  A   +   
Sbjct: 171 NSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHL 230

Query: 304 IKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH---YAFHCPHCDFACSNKHLFRK 360
           I H +   G +  EC   +C   F +   ++ H + H     + C       SN      
Sbjct: 231 IAHRRIHTGEKPYEC--SNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVT 288

Query: 361 HKK---------------------------QGHPGSEELRCTFCPFATFNPVAYQDHVGK 393
           HKK                           + H G +   C+ C  A     A   H  +
Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVH-QR 347

Query: 394 MHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSN 453
           +H  EK + C +C  A   K  LI H ++HTGEKPHKC  C       S L  H   H+ 
Sbjct: 348 IHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG 407

Query: 454 TKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSL 512
            K YMC +CG     +  L  H + H G+  Y C++C     +   L +H+  H G K  
Sbjct: 408 EKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPY 467

Query: 513 MCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLRE 572
            C  C  A  +K  L  H   + H G     Y CH C      K  ++ H+   HT  + 
Sbjct: 468 ECNTCGKAFTQKSHLNIH--QKIHTGERQ--YECHECGKAFNQKSILIVHQKI-HTGEKP 522

Query: 573 FHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           + C  C       +  + H+R   G  P
Sbjct: 523 YVCTECGRAFIRKSNFITHQRIHTGEKP 550



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 1/209 (0%)

Query: 1448 GTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERK 1507
            G +L+    C      +Q  +   +++ GEK Y C          S+LK H+++   E+ 
Sbjct: 43   GEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKL 102

Query: 1508 YLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMC 1567
            Y+C ECG       +   H   H   KP++C EC     +  +L  HQ   H   + + C
Sbjct: 103  YVCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRI-HTGEKLYEC 161

Query: 1568 EQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCN 1627
             QCGK F     L  H + H+  + + C  C +AF   + L+ H   HT    + C  C 
Sbjct: 162  SQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECG 221

Query: 1628 YKAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
                QK  ++ H R H  ++       GK
Sbjct: 222  QAFIQKTHLIAHRRIHTGEKPYECSNCGK 250



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 50/208 (24%), Positives = 81/208 (38%), Gaps = 14/208 (6%)

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK+    +C    ++K+V  +   ++ GEK ++C   +      S L  H+   +  K Y
Sbjct: 44  EKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLY 103

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLM-CEV 516
           +C ECG     K    +H + H  +  ++CN+C     +   L  H+  H G+ L  C  
Sbjct: 104 VCIECGKAFVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQ 163

Query: 517 CAFACKRKYEL----QKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLRE 572
           C        +L    + H   +HH         C  C      K  +  H+   HT  R 
Sbjct: 164 CGKGFSYNSDLSIHEKIHTGERHH--------ECTDCGKAFTQKSTLKMHQKI-HTGERS 214

Query: 573 FHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           + C  C       T L+ H+R   G  P
Sbjct: 215 YICIECGQAFIQKTHLIAHRRIHTGEKP 242



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    +  +C HC  +   +  L++H R  TG     +P +C +CG +F  +  L TH
Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTG----EKPYMCNKCGKAFTNRSNLITH 429



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           V   V  GE + + C  C         L+ H +T      +P +C ECG +F+Q+  L T
Sbjct: 568 VHQPVHTGE-KPYVCAECGKAFSGRSNLSKHQKT--HTGEKPYICSECGKTFRQKSELIT 624

Query: 884 H 884
           H
Sbjct: 625 H 625


>gi|169213999 PREDICTED: similar to hCG1778601 isoform 1 [Homo
            sapiens]
          Length = 700

 Score =  226 bits (575), Expect = 2e-58
 Identities = 158/557 (28%), Positives = 229/557 (41%), Gaps = 51/557 (9%)

Query: 1097 QKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKR 1156
            +K+K  +F+     F+C      + HQI    L E  +  C +C         L  H +R
Sbjct: 191  RKEKSFQFNESGKSFNCSS--LFKKHQI--IHLGEK-QYKCDVCGKDFNQKRYLA-HHRR 244

Query: 1157 RHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLE 1216
             H       G +P++ C  CG    +   + +H R +H G KP++C  C  + + +  L 
Sbjct: 245  CHT------GEKPYM-CNKCGKVFNKKAYLARHYR-RHTGEKPYKCNECGKTFSDKSALL 296

Query: 1217 AHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHV 1276
             H++ HTG     C+ C + F   S L  H  RVH     + C  CD     +  + RH 
Sbjct: 297  VHKTIHTGEKPYKCNECGKVFNQQSNLARHH-RVHTGEKPYQCKECDKVFSRKSYLERH- 354

Query: 1277 NSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLL 1336
               H G   + C  C+  F  ++ L QH +                T E P  C+ CG  
Sbjct: 355  RRIHTGEKPYKCKVCDKAFRHDSHLAQHIV--------------IHTREKPYKCNECGKT 400

Query: 1337 CPSPASLRGHT--RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARER 1392
                ++L  H          +C  C + F  +  L  H R       ++C+ CD     +
Sbjct: 401  FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECD-----K 455

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
            V   K +LE+H                G+ P  C  CD   R    L  H   H G + Y
Sbjct: 456  VFSRKSHLERHRRIHT-----------GEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPY 504

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            KC +C  +      +  H  IHTGEK Y C+ C  +    S L YH R+H  E+ Y C E
Sbjct: 505  KCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNE 564

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG   +  +QL  H   HTG KPY+C EC+   N    L +H+   H   + + C  C K
Sbjct: 565  CGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDK 623

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            AF     L  H R H+  KPY C VC +AF+  + L  H   HT   PF C  C    + 
Sbjct: 624  AFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRIHTGEKPFKCSECGKAFRA 683

Query: 1633 KFQVVKHVRRHHPDQAD 1649
            +  ++ H   H   + D
Sbjct: 684  QSTLIHHQAIHGVGKLD 700



 Score =  174 bits (442), Expect = 5e-43
 Identities = 121/441 (27%), Positives = 181/441 (41%), Gaps = 27/441 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F  ++ L+ H  +H  +   +C  C K F  +S L  H     GEK + 
Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C      ++ L RH   +H          Y C VC + FR    L +H+  HT    
Sbjct: 338 CKECDKVFSRKSYLERHRR-IHTG-----EKPYKCKVCDKAFRHDSHLAQHIVIHTREK- 390

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G ++   +  A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 391 ----PYKCNECGKTFG--ENSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRLH 442

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A         H   +H  
Sbjct: 443 TGEKPYKCKECDKVFSRKSHLERHRRI-HTGEKPYKCKVCDKAFRRDSHLAQHT-VIHTG 500

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H ++HTGEK +KC  C  +    S L+ H   H+  K Y
Sbjct: 501 EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPY 560

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V + +  L  H R H G+  Y+C +C    +    L  H+  H G K   C V
Sbjct: 561 KCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRVHTGEKPYKCRV 620

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A  R   L +H   + H G     Y C  C    +    +  H    HT  + F C+
Sbjct: 621 CDKAFGRDSYLAQHQ--RVHTGEKP--YKCKVCDKAFKCYSHLAQHTRI-HTGEKPFKCS 675

Query: 577 LCDYRTFSNTTLLFHKRKAHG 597
            C  + F   + L H +  HG
Sbjct: 676 ECG-KAFRAQSTLIHHQAIHG 695



 Score =  173 bits (438), Expect = 1e-42
 Identities = 129/497 (25%), Positives = 201/497 (40%), Gaps = 53/497 (10%)

Query: 119 EEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHM----------CPEC 168
           ++++V ++EKS    +S K+ +                 SLFK H           C  C
Sbjct: 185 QKQDVHRKEKSFQFNESGKSFN---------------CSSLFKKHQIIHLGEKQYKCDVC 229

Query: 169 KRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSA 228
            + F ++ +L  H   H  +    C  C K F  K+ L  H  R  GEK + C  C  + 
Sbjct: 230 GKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTF 289

Query: 229 VERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRC 288
            +++AL  H  ++H          Y C  C + F     L  H + HT        P +C
Sbjct: 290 SDKSALLVHK-TIHTG-----EKPYKCNECGKVFNQQSNLARHHRVHTGEK-----PYQC 338

Query: 289 FQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAH---HKSHYAFH 344
            +    ++   RK++++  +  H G +  +C+   C   F     +  H   H     + 
Sbjct: 339 KECDKVFS---RKSYLERHRRIHTGEKPYKCK--VCDKAFRHDSHLAQHIVIHTREKPYK 393

Query: 345 CPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCP 404
           C  C            HK   H G +  +C  C    FN  +      ++H  EK ++C 
Sbjct: 394 CNECGKTFGENSALLVHKTI-HTGEKPYKCNECG-KVFNQQSNLARHHRLHTGEKPYKCK 451

Query: 405 ECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGY 464
           EC+   + K  L RH  +HTGEKP+KC++CD   R  S+L++H + H+  K Y C ECG 
Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGK 511

Query: 465 VTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKR 523
                  L +H   H G+ RY+CN+C    +    L+ H   H G K   C  C     +
Sbjct: 512 TFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECG----K 567

Query: 524 KYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTF 583
            +  Q  +A  H   T    Y C  C      K  +  H    HT  + + C +CD    
Sbjct: 568 VFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDKAFG 626

Query: 584 SNTTLLFHKRKAHGYVP 600
            ++ L  H+R   G  P
Sbjct: 627 RDSYLAQHQRVHTGEKP 643



 Score =  163 bits (413), Expect = 1e-39
 Identities = 116/444 (26%), Positives = 169/444 (38%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           KTH+       F   + L +   +H  + S Q     K F   S  K H +  LGEK + 
Sbjct: 166 KTHISNNYGNNFFHSSLLTQKQDVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYK 225

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C +C     ++  L  H         +     Y C  C + F     L  H + HT    
Sbjct: 226 CDVCGKDFNQKRYLAHHRR------CHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEK- 278

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  C     D+ A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 279 ----PYKCNE--CGKTFSDKSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRVH 330

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A  +      H+  +H  
Sbjct: 331 TGEKPYQCKECDKVFSRKSYLERHRRI-HTGEKPYKCKVCDKAFRHDSHLAQHI-VIHTR 388

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H  +HTGEKP+KC  C       S L++H   H+  K Y
Sbjct: 389 EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPY 448

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C EC  V   K +L  H R H G+  Y+C  C     R   L+ H + H G K   C  
Sbjct: 449 KCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNE 508

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     +   L  H        T    Y C+ C     HK ++  H    HT  + + C 
Sbjct: 509 CGKTFVQNSSLVMHKVIH----TGEKRYKCNECGKSFNHKSSLAYHHRL-HTGEKPYKCN 563

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C     + + L  H R   G  P
Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKP 587



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 57/204 (27%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHT----GEKPYHCHLCPYACADPSRLKYHM 1499
            +G  G +L K  + A S    Q+I+   + H     G   +H  L          L    
Sbjct: 138  EGKIGNQLEKSINNASSVSTSQRISCRPKTHISNNYGNNFFHSSL----------LTQKQ 187

Query: 1500 RIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRH 1559
             +H++E+ +   E G      +  K H   H G K Y+C  C    N+   L  H    H
Sbjct: 188  DVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYL-AHHRRCH 246

Query: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRH 1619
               + +MC +CGK F  +  L  H R+H+  KPY CN C + F   + L  H   HT   
Sbjct: 247  TGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEK 306

Query: 1620 PFFCRLCNYKAKQKFQVVKHVRRH 1643
            P+ C  C     Q+  + +H R H
Sbjct: 307  PYKCNECGKVFNQQSNLARHHRVH 330



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 825 QMVVIQGEGRAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGLS 882
           Q +VI    + ++C  C        AL +H    TG     +P  C ECG  F QQ  L+
Sbjct: 381 QHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTG----EKPYKCNECGKVFNQQSNLA 436

Query: 883 TH 884
            H
Sbjct: 437 RH 438


>gi|169214410 PREDICTED: similar to hCG1778601 isoform 1 [Homo
            sapiens]
          Length = 700

 Score =  226 bits (575), Expect = 2e-58
 Identities = 158/557 (28%), Positives = 229/557 (41%), Gaps = 51/557 (9%)

Query: 1097 QKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKR 1156
            +K+K  +F+     F+C      + HQI    L E  +  C +C         L  H +R
Sbjct: 191  RKEKSFQFNESGKSFNCSS--LFKKHQI--IHLGEK-QYKCDVCGKDFNQKRYLA-HHRR 244

Query: 1157 RHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLE 1216
             H       G +P++ C  CG    +   + +H R +H G KP++C  C  + + +  L 
Sbjct: 245  CHT------GEKPYM-CNKCGKVFNKKAYLARHYR-RHTGEKPYKCNECGKTFSDKSALL 296

Query: 1217 AHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHV 1276
             H++ HTG     C+ C + F   S L  H  RVH     + C  CD     +  + RH 
Sbjct: 297  VHKTIHTGEKPYKCNECGKVFNQQSNLARHH-RVHTGEKPYQCKECDKVFSRKSYLERH- 354

Query: 1277 NSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLL 1336
               H G   + C  C+  F  ++ L QH +                T E P  C+ CG  
Sbjct: 355  RRIHTGEKPYKCKVCDKAFRHDSHLAQHIV--------------IHTREKPYKCNECGKT 400

Query: 1337 CPSPASLRGHT--RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARER 1392
                ++L  H          +C  C + F  +  L  H R       ++C+ CD     +
Sbjct: 401  FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECD-----K 455

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
            V   K +LE+H                G+ P  C  CD   R    L  H   H G + Y
Sbjct: 456  VFSRKSHLERHRRIHT-----------GEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPY 504

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            KC +C  +      +  H  IHTGEK Y C+ C  +    S L YH R+H  E+ Y C E
Sbjct: 505  KCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNE 564

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG   +  +QL  H   HTG KPY+C EC+   N    L +H+   H   + + C  C K
Sbjct: 565  CGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDK 623

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            AF     L  H R H+  KPY C VC +AF+  + L  H   HT   PF C  C    + 
Sbjct: 624  AFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRIHTGEKPFKCSECGKAFRA 683

Query: 1633 KFQVVKHVRRHHPDQAD 1649
            +  ++ H   H   + D
Sbjct: 684  QSTLIHHQAIHGVGKLD 700



 Score =  174 bits (442), Expect = 5e-43
 Identities = 121/441 (27%), Positives = 181/441 (41%), Gaps = 27/441 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F  ++ L+ H  +H  +   +C  C K F  +S L  H     GEK + 
Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C      ++ L RH   +H          Y C VC + FR    L +H+  HT    
Sbjct: 338 CKECDKVFSRKSYLERHRR-IHTG-----EKPYKCKVCDKAFRHDSHLAQHIVIHTREK- 390

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G ++   +  A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 391 ----PYKCNECGKTFG--ENSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRLH 442

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A         H   +H  
Sbjct: 443 TGEKPYKCKECDKVFSRKSHLERHRRI-HTGEKPYKCKVCDKAFRRDSHLAQHT-VIHTG 500

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H ++HTGEK +KC  C  +    S L+ H   H+  K Y
Sbjct: 501 EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPY 560

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V + +  L  H R H G+  Y+C +C    +    L  H+  H G K   C V
Sbjct: 561 KCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRVHTGEKPYKCRV 620

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A  R   L +H   + H G     Y C  C    +    +  H    HT  + F C+
Sbjct: 621 CDKAFGRDSYLAQHQ--RVHTGEKP--YKCKVCDKAFKCYSHLAQHTRI-HTGEKPFKCS 675

Query: 577 LCDYRTFSNTTLLFHKRKAHG 597
            C  + F   + L H +  HG
Sbjct: 676 ECG-KAFRAQSTLIHHQAIHG 695



 Score =  173 bits (438), Expect = 1e-42
 Identities = 129/497 (25%), Positives = 201/497 (40%), Gaps = 53/497 (10%)

Query: 119 EEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHM----------CPEC 168
           ++++V ++EKS    +S K+ +                 SLFK H           C  C
Sbjct: 185 QKQDVHRKEKSFQFNESGKSFN---------------CSSLFKKHQIIHLGEKQYKCDVC 229

Query: 169 KRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSA 228
            + F ++ +L  H   H  +    C  C K F  K+ L  H  R  GEK + C  C  + 
Sbjct: 230 GKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTF 289

Query: 229 VERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRC 288
            +++AL  H  ++H          Y C  C + F     L  H + HT        P +C
Sbjct: 290 SDKSALLVHK-TIHTG-----EKPYKCNECGKVFNQQSNLARHHRVHTGEK-----PYQC 338

Query: 289 FQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAH---HKSHYAFH 344
            +    ++   RK++++  +  H G +  +C+   C   F     +  H   H     + 
Sbjct: 339 KECDKVFS---RKSYLERHRRIHTGEKPYKCK--VCDKAFRHDSHLAQHIVIHTREKPYK 393

Query: 345 CPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCP 404
           C  C            HK   H G +  +C  C    FN  +      ++H  EK ++C 
Sbjct: 394 CNECGKTFGENSALLVHKTI-HTGEKPYKCNECG-KVFNQQSNLARHHRLHTGEKPYKCK 451

Query: 405 ECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGY 464
           EC+   + K  L RH  +HTGEKP+KC++CD   R  S+L++H + H+  K Y C ECG 
Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGK 511

Query: 465 VTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKR 523
                  L +H   H G+ RY+CN+C    +    L+ H   H G K   C  C     +
Sbjct: 512 TFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECG----K 567

Query: 524 KYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTF 583
            +  Q  +A  H   T    Y C  C      K  +  H    HT  + + C +CD    
Sbjct: 568 VFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDKAFG 626

Query: 584 SNTTLLFHKRKAHGYVP 600
            ++ L  H+R   G  P
Sbjct: 627 RDSYLAQHQRVHTGEKP 643



 Score =  163 bits (413), Expect = 1e-39
 Identities = 116/444 (26%), Positives = 169/444 (38%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           KTH+       F   + L +   +H  + S Q     K F   S  K H +  LGEK + 
Sbjct: 166 KTHISNNYGNNFFHSSLLTQKQDVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYK 225

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C +C     ++  L  H         +     Y C  C + F     L  H + HT    
Sbjct: 226 CDVCGKDFNQKRYLAHHRR------CHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEK- 278

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  C     D+ A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 279 ----PYKCNE--CGKTFSDKSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRVH 330

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A  +      H+  +H  
Sbjct: 331 TGEKPYQCKECDKVFSRKSYLERHRRI-HTGEKPYKCKVCDKAFRHDSHLAQHI-VIHTR 388

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H  +HTGEKP+KC  C       S L++H   H+  K Y
Sbjct: 389 EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPY 448

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C EC  V   K +L  H R H G+  Y+C  C     R   L+ H + H G K   C  
Sbjct: 449 KCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNE 508

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     +   L  H        T    Y C+ C     HK ++  H    HT  + + C 
Sbjct: 509 CGKTFVQNSSLVMHKVIH----TGEKRYKCNECGKSFNHKSSLAYHHRL-HTGEKPYKCN 563

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C     + + L  H R   G  P
Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKP 587



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 57/204 (27%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHT----GEKPYHCHLCPYACADPSRLKYHM 1499
            +G  G +L K  + A S    Q+I+   + H     G   +H  L          L    
Sbjct: 138  EGKIGNQLEKSINNASSVSTSQRISCRPKTHISNNYGNNFFHSSL----------LTQKQ 187

Query: 1500 RIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRH 1559
             +H++E+ +   E G      +  K H   H G K Y+C  C    N+   L  H    H
Sbjct: 188  DVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYL-AHHRRCH 246

Query: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRH 1619
               + +MC +CGK F  +  L  H R+H+  KPY CN C + F   + L  H   HT   
Sbjct: 247  TGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEK 306

Query: 1620 PFFCRLCNYKAKQKFQVVKHVRRH 1643
            P+ C  C     Q+  + +H R H
Sbjct: 307  PYKCNECGKVFNQQSNLARHHRVH 330



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 825 QMVVIQGEGRAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGLS 882
           Q +VI    + ++C  C        AL +H    TG     +P  C ECG  F QQ  L+
Sbjct: 381 QHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTG----EKPYKCNECGKVFNQQSNLA 436

Query: 883 TH 884
            H
Sbjct: 437 RH 438


>gi|169213416 PREDICTED: hypothetical protein LOC388559 [Homo sapiens]
          Length = 700

 Score =  226 bits (575), Expect = 2e-58
 Identities = 158/557 (28%), Positives = 229/557 (41%), Gaps = 51/557 (9%)

Query: 1097 QKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKR 1156
            +K+K  +F+     F+C      + HQI    L E  +  C +C         L  H +R
Sbjct: 191  RKEKSFQFNESGKSFNCSS--LFKKHQI--IHLGEK-QYKCDVCGKDFNQKRYLA-HHRR 244

Query: 1157 RHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLE 1216
             H       G +P++ C  CG    +   + +H R +H G KP++C  C  + + +  L 
Sbjct: 245  CHT------GEKPYM-CNKCGKVFNKKAYLARHYR-RHTGEKPYKCNECGKTFSDKSALL 296

Query: 1217 AHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHV 1276
             H++ HTG     C+ C + F   S L  H  RVH     + C  CD     +  + RH 
Sbjct: 297  VHKTIHTGEKPYKCNECGKVFNQQSNLARHH-RVHTGEKPYQCKECDKVFSRKSYLERH- 354

Query: 1277 NSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLL 1336
               H G   + C  C+  F  ++ L QH +                T E P  C+ CG  
Sbjct: 355  RRIHTGEKPYKCKVCDKAFRHDSHLAQHIV--------------IHTREKPYKCNECGKT 400

Query: 1337 CPSPASLRGHT--RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARER 1392
                ++L  H          +C  C + F  +  L  H R       ++C+ CD     +
Sbjct: 401  FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECD-----K 455

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
            V   K +LE+H                G+ P  C  CD   R    L  H   H G + Y
Sbjct: 456  VFSRKSHLERHRRIHT-----------GEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPY 504

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            KC +C  +      +  H  IHTGEK Y C+ C  +    S L YH R+H  E+ Y C E
Sbjct: 505  KCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNE 564

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG   +  +QL  H   HTG KPY+C EC+   N    L +H+   H   + + C  C K
Sbjct: 565  CGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDK 623

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            AF     L  H R H+  KPY C VC +AF+  + L  H   HT   PF C  C    + 
Sbjct: 624  AFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRIHTGEKPFKCSECGKAFRA 683

Query: 1633 KFQVVKHVRRHHPDQAD 1649
            +  ++ H   H   + D
Sbjct: 684  QSTLIHHQAIHGVGKLD 700



 Score =  174 bits (442), Expect = 5e-43
 Identities = 121/441 (27%), Positives = 181/441 (41%), Gaps = 27/441 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F  ++ L+ H  +H  +   +C  C K F  +S L  H     GEK + 
Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C      ++ L RH   +H          Y C VC + FR    L +H+  HT    
Sbjct: 338 CKECDKVFSRKSYLERHRR-IHTG-----EKPYKCKVCDKAFRHDSHLAQHIVIHTREK- 390

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C + G ++   +  A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 391 ----PYKCNECGKTFG--ENSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRLH 442

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A         H   +H  
Sbjct: 443 TGEKPYKCKECDKVFSRKSHLERHRRI-HTGEKPYKCKVCDKAFRRDSHLAQHT-VIHTG 500

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H ++HTGEK +KC  C  +    S L+ H   H+  K Y
Sbjct: 501 EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPY 560

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C ECG V + +  L  H R H G+  Y+C +C    +    L  H+  H G K   C V
Sbjct: 561 KCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRVHTGEKPYKCRV 620

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A  R   L +H   + H G     Y C  C    +    +  H    HT  + F C+
Sbjct: 621 CDKAFGRDSYLAQHQ--RVHTGEKP--YKCKVCDKAFKCYSHLAQHTRI-HTGEKPFKCS 675

Query: 577 LCDYRTFSNTTLLFHKRKAHG 597
            C  + F   + L H +  HG
Sbjct: 676 ECG-KAFRAQSTLIHHQAIHG 695



 Score =  173 bits (438), Expect = 1e-42
 Identities = 129/497 (25%), Positives = 201/497 (40%), Gaps = 53/497 (10%)

Query: 119 EEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHM----------CPEC 168
           ++++V ++EKS    +S K+ +                 SLFK H           C  C
Sbjct: 185 QKQDVHRKEKSFQFNESGKSFN---------------CSSLFKKHQIIHLGEKQYKCDVC 229

Query: 169 KRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSA 228
            + F ++ +L  H   H  +    C  C K F  K+ L  H  R  GEK + C  C  + 
Sbjct: 230 GKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTF 289

Query: 229 VERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRC 288
            +++AL  H  ++H          Y C  C + F     L  H + HT        P +C
Sbjct: 290 SDKSALLVHK-TIHTG-----EKPYKCNECGKVFNQQSNLARHHRVHTGEK-----PYQC 338

Query: 289 FQEGCSYAAPDRKAFIKHLKETH-GVRAVECRHHSCPMLFATAEAMEAH---HKSHYAFH 344
            +    ++   RK++++  +  H G +  +C+   C   F     +  H   H     + 
Sbjct: 339 KECDKVFS---RKSYLERHRRIHTGEKPYKCK--VCDKAFRHDSHLAQHIVIHTREKPYK 393

Query: 345 CPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCP 404
           C  C            HK   H G +  +C  C    FN  +      ++H  EK ++C 
Sbjct: 394 CNECGKTFGENSALLVHKTI-HTGEKPYKCNECG-KVFNQQSNLARHHRLHTGEKPYKCK 451

Query: 405 ECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGY 464
           EC+   + K  L RH  +HTGEKP+KC++CD   R  S+L++H + H+  K Y C ECG 
Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGK 511

Query: 465 VTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKR 523
                  L +H   H G+ RY+CN+C    +    L+ H   H G K   C  C     +
Sbjct: 512 TFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECG----K 567

Query: 524 KYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTF 583
            +  Q  +A  H   T    Y C  C      K  +  H    HT  + + C +CD    
Sbjct: 568 VFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRV-HTGEKPYKCRVCDKAFG 626

Query: 584 SNTTLLFHKRKAHGYVP 600
            ++ L  H+R   G  P
Sbjct: 627 RDSYLAQHQRVHTGEKP 643



 Score =  163 bits (413), Expect = 1e-39
 Identities = 116/444 (26%), Positives = 169/444 (38%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           KTH+       F   + L +   +H  + S Q     K F   S  K H +  LGEK + 
Sbjct: 166 KTHISNNYGNNFFHSSLLTQKQDVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYK 225

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C +C     ++  L  H         +     Y C  C + F     L  H + HT    
Sbjct: 226 CDVCGKDFNQKRYLAHHRR------CHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEK- 278

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  C     D+ A + H     G +  +C  + C  +F     +  HH+ H
Sbjct: 279 ----PYKCNE--CGKTFSDKSALLVHKTIHTGEKPYKC--NECGKVFNQQSNLARHHRVH 330

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  CD   S K    +H++  H G +  +C  C  A  +      H+  +H  
Sbjct: 331 TGEKPYQCKECDKVFSRKSYLERHRRI-HTGEKPYKCKVCDKAFRHDSHLAQHI-VIHTR 388

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC         L+ H  +HTGEKP+KC  C       S L++H   H+  K Y
Sbjct: 389 EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPY 448

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C EC  V   K +L  H R H G+  Y+C  C     R   L+ H + H G K   C  
Sbjct: 449 KCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNE 508

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     +   L  H        T    Y C+ C     HK ++  H    HT  + + C 
Sbjct: 509 CGKTFVQNSSLVMHKVIH----TGEKRYKCNECGKSFNHKSSLAYHHRL-HTGEKPYKCN 563

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C     + + L  H R   G  P
Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKP 587



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 57/204 (27%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHT----GEKPYHCHLCPYACADPSRLKYHM 1499
            +G  G +L K  + A S    Q+I+   + H     G   +H  L          L    
Sbjct: 138  EGKIGNQLEKSINNASSVSTSQRISCRPKTHISNNYGNNFFHSSL----------LTQKQ 187

Query: 1500 RIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRH 1559
             +H++E+ +   E G      +  K H   H G K Y+C  C    N+   L  H    H
Sbjct: 188  DVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYL-AHHRRCH 246

Query: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRH 1619
               + +MC +CGK F  +  L  H R+H+  KPY CN C + F   + L  H   HT   
Sbjct: 247  TGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEK 306

Query: 1620 PFFCRLCNYKAKQKFQVVKHVRRH 1643
            P+ C  C     Q+  + +H R H
Sbjct: 307  PYKCNECGKVFNQQSNLARHHRVH 330



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 825 QMVVIQGEGRAFRCPHCPFITRREKALNLHS--RTGCQGRREPLLCPECGASFKQQRGLS 882
           Q +VI    + ++C  C        AL +H    TG     +P  C ECG  F QQ  L+
Sbjct: 381 QHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTG----EKPYKCNECGKVFNQQSNLA 436

Query: 883 TH 884
            H
Sbjct: 437 RH 438


>gi|194018469 zinc finger protein 546 [Homo sapiens]
          Length = 836

 Score =  226 bits (575), Expect = 2e-58
 Identities = 160/554 (28%), Positives = 231/554 (41%), Gaps = 48/554 (8%)

Query: 1110 PFSCQQ-ERALRTHQIRGCPLEESGELHCSLCPFTAPAATAL--RLHQKRRHPTAAPARG 1166
            P+ C++  +A R H      L E   +H  + P+          R+   R H T     G
Sbjct: 272  PYECKECGKAFRLHY----HLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTIHA--G 325

Query: 1167 PRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIG 1226
             RP+ +C +CG   +    + +H+R+ H G +P++C  C  +   +  +  HQ  HTG+ 
Sbjct: 326  ERPY-ECKECGKAFRLHYQLTEHQRI-HTGERPYECKVCGKTFRVQRHISQHQKIHTGVK 383

Query: 1227 RIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAF 1286
               C+ C + F   S L  H+ ++H     + C  C  S     ++ RH    H G   +
Sbjct: 384  PYKCNECGKAFSHGSYLVQHQ-KIHTGEKPYECKECGKSFSFHAELARH-RRIHTGEKPY 441

Query: 1287 ACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCG--LLCPSPASLR 1344
             C +C   F  +T L +H  R H             T E P  C  CG   +C    +L 
Sbjct: 442  ECRECGKAFRLQTELTRHH-RTH-------------TGEKPYECKECGKAFICGYQLTLH 487

Query: 1345 GHTRKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYL-- 1400
              T       EC  C + F SR  L +H R       + C  C  A R +  L +H+   
Sbjct: 488  LRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIH 547

Query: 1401 ---EQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRH-------QLVLDHHVKGHGGTR 1450
               + +E      A    +       +H     + C+        +  L  H K H G +
Sbjct: 548  TCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEK 607

Query: 1451 LYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLC 1510
             Y C +C  + + + ++T H RIHTGEKPY C  C  A    + L  H RIH  E+ Y C
Sbjct: 608  PYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYEC 667

Query: 1511 PECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQC 1570
             ECG        L  H   HTG KPY C EC      +  L +HQ   H     + C++C
Sbjct: 668  TECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRI-HTGELPYECKEC 726

Query: 1571 GKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKA 1630
            GK F  R+ L  H R H+  KPY C  C  AFR  A L  H + HT   P+ C+ C    
Sbjct: 727  GKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKECG--- 783

Query: 1631 KQKFQVVKHVRRHH 1644
             + F V   + RHH
Sbjct: 784  -KAFSVNSELTRHH 796



 Score =  217 bits (553), Expect = 7e-56
 Identities = 165/560 (29%), Positives = 228/560 (40%), Gaps = 53/560 (9%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAP-AATALRLH-QKRRHPTA 1161
            + C  C  +  + R LR HQ           +H    P+       A RLH Q   H   
Sbjct: 301  YECKECGKAFSRVRDLRVHQT----------IHAGERPYECKECGKAFRLHYQLTEHQRI 350

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G RP+ +C  CG T +  R + QH+++ H GVKP++C  C  + +    L  HQ  
Sbjct: 351  HT--GERPY-ECKVCGKTFRVQRHISQHQKI-HTGVKPYKCNECGKAFSHGSYLVQHQKI 406

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C  C ++F  +++L  HR R+H     + C  C  +  L+ ++TRH +  H 
Sbjct: 407  HTGEKPYECKECGKSFSFHAELARHR-RIHTGEKPYECRECGKAFRLQTELTRH-HRTHT 464

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C   F     L  H LR H             T E P  C  CG    S  
Sbjct: 465  GEKPYECKECGKAFICGYQLTLH-LRTH-------------TGEIPYECKECGKTFSSRY 510

Query: 1342 SLRGHTR---KQHPRLECGACQEAFPSRLALDEHRRQQHFS--HRCQLCDFAARERVGLV 1396
             L  H R    + P + C  C +AF  +  L  H R       + C+ C  A       +
Sbjct: 511  HLTQHYRIHTGEKPYI-CNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAFIHSNQFI 569

Query: 1397 KHYLEQHEETSAAVAASDGDG-------------DAGQPPLHCPFCDFTCRHQLVLDHHV 1443
             H    H   S  +    G                 G+ P  C  C    R Q  L  H 
Sbjct: 570  SHQ-RIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEKPYICNECGKAFRFQTELTQHH 628

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHK 1503
            + H G + YKCT+C  +      +T H RIHTGEKPY C  C    +    L  H R H 
Sbjct: 629  RIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRGHT 688

Query: 1504 EERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREAR 1563
             E+ Y+C ECG       +L  H   HTG  PY+C EC    +R   L  H    H   +
Sbjct: 689  GEKPYICNECGNAFICSYRLTLHQRIHTGELPYECKECGKTFSRRYHLTQHFRL-HTGEK 747

Query: 1564 AFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFC 1623
             + C++CG AF+ +  L  H   H+  KPY C  C +AF   + L  H   HT   P+ C
Sbjct: 748  PYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSVNSELTRHHRIHTGEKPYQC 807

Query: 1624 RLCNYKAKQKFQVVKHVRRH 1643
            + C     +  Q+  H R H
Sbjct: 808  KECGKAFIRSDQLTLHQRNH 827



 Score =  197 bits (502), Expect = 5e-50
 Identities = 130/485 (26%), Positives = 189/485 (38%), Gaps = 73/485 (15%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G RP+ +C +CG    +   ++ H  + H G +P++C  C  +    Y L  HQ  H+G+
Sbjct: 241  GERPY-KCMECGKAFCRVGDLRVHHTI-HAGERPYECKECGKAFRLHYHLTEHQRIHSGV 298

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C  C + F     LR+H+  +H     + C  C  +  L + +T H    H G   
Sbjct: 299  KPYECKECGKAFSRVRDLRVHQT-IHAGERPYECKECGKAFRLHYQLTEH-QRIHTGERP 356

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            + C  C   F  +  + QH                  T   P  C+ CG      A   G
Sbjct: 357  YECKVCGKTFRVQRHISQH--------------QKIHTGVKPYKCNECG-----KAFSHG 397

Query: 1346 HTRKQHPRL-------ECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKH 1398
                QH ++       EC  C ++F     L  HRR                        
Sbjct: 398  SYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIH---------------------- 435

Query: 1399 YLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCA 1458
                                 G+ P  C  C    R Q  L  H + H G + Y+C +C 
Sbjct: 436  --------------------TGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECG 475

Query: 1459 YSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCK 1518
             +     ++T H R HTGE PY C  C    +    L  H RIH  E+ Y+C ECG   +
Sbjct: 476  KAFICGYQLTLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFR 535

Query: 1519 WVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRF 1578
               +L  H   HT  KPY+C EC      ++    HQ   H     ++C++CGK F  R+
Sbjct: 536  LQGELTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRI-HTSESTYICKECGKIFSRRY 594

Query: 1579 LLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVK 1638
             L  H + H+  KPY+CN C +AFR+   L  H   HT   P+ C  C     +   + +
Sbjct: 595  NLTQHFKIHTGEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQ 654

Query: 1639 HVRRH 1643
            H R H
Sbjct: 655  HHRIH 659



 Score =  177 bits (450), Expect = 6e-44
 Identities = 119/380 (31%), Positives = 156/380 (41%), Gaps = 31/380 (8%)

Query: 1280 HQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPS 1339
            H    ++ C +C   F  ++ L QH LR H             T E P  C  CG     
Sbjct: 211  HAREKSYECKECRKAFRQQSYLIQH-LRIH-------------TGERPYKCMECGKAFCR 256

Query: 1340 PASLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQHF--SHRCQLCDFAARE---- 1391
               LR H          EC  C +AF     L EH+R       + C+ C  A       
Sbjct: 257  VGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDL 316

Query: 1392 RVGLVKHYLEQHEETSAAVAA--------SDGDGDAGQPPLHCPFCDFTCRHQLVLDHHV 1443
            RV    H  E+  E      A               G+ P  C  C  T R Q  +  H 
Sbjct: 317  RVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQ 376

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHK 1503
            K H G + YKC +C  +  +   +  H +IHTGEKPY C  C  + +  + L  H RIH 
Sbjct: 377  KIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHT 436

Query: 1504 EERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREAR 1563
             E+ Y C ECG   +   +L  H   HTG KPY+C EC         L +H  T H    
Sbjct: 437  GEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLRT-HTGEI 495

Query: 1564 AFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFC 1623
             + C++CGK F +R+ L  H R H+  KPY+CN C +AFR    L  H   HT   P+ C
Sbjct: 496  PYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYEC 555

Query: 1624 RLCNYKAKQKFQVVKHVRRH 1643
            + C        Q + H R H
Sbjct: 556  KECGKAFIHSNQFISHQRIH 575



 Score =  164 bits (416), Expect = 5e-40
 Identities = 120/444 (27%), Positives = 185/444 (41%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F   ++LV+H  +H  +   +C  C K F+  ++L  H     GEK + 
Sbjct: 383 KPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYE 442

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   +  L RH  +   +        Y C  C + F     L  HL++HT    
Sbjct: 443 CRECGKAFRLQTELTRHHRTHTGE------KPYECKECGKAFICGYQLTLHLRTHTGE-- 494

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
              +P  C + G ++++  R    +H +   G +   C  + C   F     +  HH+ H
Sbjct: 495 ---IPYECKECGKTFSS--RYHLTQHYRIHTGEKPYIC--NECGKAFRLQGELTRHHRIH 547

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A  + + F  H++  H       C  C            H  K+H  
Sbjct: 548 TCEKPYECKECGKAFIHSNQFISHQRI-HTSESTYICKECGKIFSRRYNLTQHF-KIHTG 605

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK + C EC  A   +  L +H  +HTGEKP+KC  C       ++L++H   H+  K Y
Sbjct: 606 EKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPY 665

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK-SLMCEV 516
            CTECG      ++L  H R H G+  Y CN+C      + +L+ H+  H G+    C+ 
Sbjct: 666 ECTECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRIHTGELPYECKE 725

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     R+Y L +H   + H G     Y C  C    R  QA L+  +  HT  + + C 
Sbjct: 726 CGKTFSRRYHLTQHF--RLHTGEKP--YSCKECGNAFR-LQAELTRHHIVHTGEKPYKCK 780

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C      N+ L  H R   G  P
Sbjct: 781 ECGKAFSVNSELTRHHRIHTGEKP 804



 Score =  162 bits (410), Expect = 3e-39
 Identities = 119/467 (25%), Positives = 191/467 (40%), Gaps = 44/467 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K++ C EC++ F+++++L++HL +H  +   +C  C K F     L+ H     GE+ + 
Sbjct: 215 KSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHAGERPYE 274

Query: 221 CPLC------HYSAVERNALNRHM-----------------ASMHEDISNFYSDTYACPV 257
           C  C      HY   E   ++  +                   +H+ I +     Y C  
Sbjct: 275 CKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTI-HAGERPYECKE 333

Query: 258 CREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVE 317
           C + FRL   L EH + HT        P  C  + C      ++   +H K   GV+  +
Sbjct: 334 CGKAFRLHYQLTEHQRIHTGER-----PYEC--KVCGKTFRVQRHISQHQKIHTGVKPYK 386

Query: 318 CRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRC 374
           C  + C   F+    +  H K H     + C  C  + S      +H++  H G +   C
Sbjct: 387 C--NECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRI-HTGEKPYEC 443

Query: 375 TFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELC 434
             C  A         H  + H  EK ++C EC  A      L  H+  HTGE P++C+ C
Sbjct: 444 RECGKAFRLQTELTRH-HRTHTGEKPYECKECGKAFICGYQLTLHLRTHTGEIPYECKEC 502

Query: 435 DFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRC 494
             T     +L++H   H+  K Y+C ECG   + +  L  H R H  +  Y+C +C    
Sbjct: 503 GKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAF 562

Query: 495 HRADQLSSHKLRHQGKS-LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQS 553
             ++Q  SH+  H  +S  +C+ C     R+Y L +H   + H G     Y C+ C    
Sbjct: 563 IHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHF--KIHTGEKP--YICNECGKAF 618

Query: 554 RHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           R +  +  H    HT  + + C  C      +T L  H R   G  P
Sbjct: 619 RFQTELTQHHRI-HTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKP 664



 Score =  151 bits (382), Expect = 5e-36
 Identities = 98/353 (27%), Positives = 146/353 (41%), Gaps = 20/353 (5%)

Query: 165 CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLC 224
           C EC + F  R HL +H  +H  +    C  C K F  + +L  H      EK + C  C
Sbjct: 499 CKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKEC 558

Query: 225 HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPL 284
             + +  N    H   +H   S     TY C  C + F     L +H K HT        
Sbjct: 559 GKAFIHSNQFISHQR-IHTSES-----TYICKECGKIFSRRYNLTQHFKIHTGEK----- 607

Query: 285 PLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA-- 342
           P  C +  C  A   +    +H +   G +  +C    C   F  +  +  HH+ H    
Sbjct: 608 PYICNE--CGKAFRFQTELTQHHRIHTGEKPYKCTE--CGKAFIRSTHLTQHHRIHTGEK 663

Query: 343 -FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIH 401
            + C  C    S  +   +H + GH G +   C  C  A         H  ++H  E  +
Sbjct: 664 PYECTECGKTFSRHYHLTQHHR-GHTGEKPYICNECGNAFICSYRLTLHQ-RIHTGELPY 721

Query: 402 QCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTE 461
           +C EC    + +  L +H  LHTGEKP+ C+ C    R  + L++H + H+  K Y C E
Sbjct: 722 ECKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKE 781

Query: 462 CGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMC 514
           CG        L  H R H G+  YQC +C     R+DQL+ H+  H  + ++C
Sbjct: 782 CGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNHISEEVLC 834



 Score =  150 bits (379), Expect = 1e-35
 Identities = 113/446 (25%), Positives = 169/446 (37%), Gaps = 39/446 (8%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           + + C EC + F+   HL EH  +H      +C  C K F+    L+ H     GE+ + 
Sbjct: 271 RPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTIHAGERPYE 330

Query: 221 CPLC------HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKS 274
           C  C      HY   E   ++                 Y C VC + FR+ + + +H K 
Sbjct: 331 CKECGKAFRLHYQLTEHQRIHTG------------ERPYECKVCGKTFRVQRHISQHQKI 378

Query: 275 HTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAME 334
           HT        P +C +  C  A       ++H K   G +  EC+   C   F+    + 
Sbjct: 379 HTGVK-----PYKCNE--CGKAFSHGSYLVQHQKIHTGEKPYECKE--CGKSFSFHAELA 429

Query: 335 AHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHV 391
            H + H     + C  C  A   +    +H +  H G +   C  C  A         H+
Sbjct: 430 RHRRIHTGEKPYECRECGKAFRLQTELTRHHRT-HTGEKPYECKECGKAFICGYQLTLHL 488

Query: 392 GKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTH 451
            + H  E  ++C EC    + +  L +H  +HTGEKP+ C  C    R    L++H   H
Sbjct: 489 -RTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIH 547

Query: 452 SNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-K 510
           +  K Y C ECG      +    H R H  +  Y C +C     R   L+ H   H G K
Sbjct: 548 TCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEK 607

Query: 511 SLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRL 570
             +C  C  A + + EL +H    H   T    Y C  C         +  H    HT  
Sbjct: 608 PYICNECGKAFRFQTELTQH----HRIHTGEKPYKCTECGKAFIRSTHLTQHHRI-HTGE 662

Query: 571 REFHCALCDYRTFSNTTLLFHKRKAH 596
           + + C  C  +TFS    L    + H
Sbjct: 663 KPYECTECG-KTFSRHYHLTQHHRGH 687



 Score =  148 bits (373), Expect = 5e-35
 Identities = 74/202 (36%), Positives = 101/202 (50%), Gaps = 1/202 (0%)

Query: 1442 HVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRI 1501
            H K H   + Y+C +C  + + +  +  H RIHTGE+PY C  C  A      L+ H  I
Sbjct: 207  HPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTI 266

Query: 1502 HKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHRE 1561
            H  ER Y C ECG   +    L  H   H+G+KPY+C EC    +R   LRVHQ T H  
Sbjct: 267  HAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQ-TIHAG 325

Query: 1562 ARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPF 1621
             R + C++CGKAF+  + L  H R H+  +PY C VC + FR    +  H   HT   P+
Sbjct: 326  ERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQKIHTGVKPY 385

Query: 1622 FCRLCNYKAKQKFQVVKHVRRH 1643
             C  C         +V+H + H
Sbjct: 386  KCNECGKAFSHGSYLVQHQKIH 407



 Score =  113 bits (282), Expect = 2e-24
 Identities = 64/205 (31%), Positives = 99/205 (48%), Gaps = 7/205 (3%)

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           K+HA EK ++C EC  A   +  LI+H+ +HTGE+P+KC  C      V  L  H   H+
Sbjct: 209 KIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHA 268

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             + Y C ECG   +  ++L  H R H+G   Y+C +C     R   L  H+  H G + 
Sbjct: 269 GERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTIHAGERP 328

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C+ C  A +  Y+L +H   + H G     Y C  C    R ++ +  H+   HT ++
Sbjct: 329 YECKECGKAFRLHYQLTEH--QRIHTGERP--YECKVCGKTFRVQRHISQHQKI-HTGVK 383

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAH 596
            + C  C  + FS+ + L   +K H
Sbjct: 384 PYKCNECG-KAFSHGSYLVQHQKIH 407



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 93/402 (23%), Positives = 144/402 (35%), Gaps = 66/402 (16%)

Query: 1104 FSCPTC--PFSC--QQERALRTHQIRGCPLEESGEL--HCSLCPFTAPAATALRLHQKRR 1157
            + C  C   F C  Q    LRTH         +GE+   C  C  T  +   L  H +  
Sbjct: 469  YECKECGKAFICGYQLTLHLRTH---------TGEIPYECKECGKTFSSRYHLTQHYRIH 519

Query: 1158 HPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEA 1217
                    G +P++ C +CG   +    + +H R+ H   KP++C  C  +     +  +
Sbjct: 520  -------TGEKPYI-CNECGKAFRLQGELTRHHRI-HTCEKPYECKECGKAFIHSNQFIS 570

Query: 1218 HQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVN 1277
            HQ  HT      C  C + F     L  H  ++H     + C  C  +   + ++T+H +
Sbjct: 571  HQRIHTSESTYICKECGKIFSRRYNLTQH-FKIHTGEKPYICNECGKAFRFQTELTQH-H 628

Query: 1278 SCHQGTPAFACSQCEAQFSSETALKQH-----------------ALRRHPEPAQPAPGSP 1320
              H G   + C++C   F   T L QH                    RH    Q   G  
Sbjct: 629  RIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRG-- 686

Query: 1321 AETTEGPLHCSRCG--LLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQ-- 1376
              T E P  C+ CG   +C    +L           EC  C + F  R  L +H R    
Sbjct: 687  -HTGEKPYICNECGNAFICSYRLTLHQRIHTGELPYECKECGKTFSRRYHLTQHFRLHTG 745

Query: 1377 HFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQ 1436
               + C+ C  A R +  L +H++                   G+ P  C  C       
Sbjct: 746  EKPYSCKECGNAFRLQAELTRHHIVH----------------TGEKPYKCKECGKAFSVN 789

Query: 1437 LVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEK 1478
              L  H + H G + Y+C +C  +     ++T H R H  E+
Sbjct: 790  SELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNHISEE 831



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 52/217 (23%), Positives = 80/217 (36%), Gaps = 20/217 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + THL +H  +H  +   +C  C K F+    L  H     GEK + 
Sbjct: 635 KPYKCTECGKAFIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRGHTGEKPYI 694

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  + +    L  H      ++       Y C  C + F     L +H + HT    
Sbjct: 695 CNECGNAFICSYRLTLHQRIHTGEL------PYECKECGKTFSRRYHLTQHFRLHTGEK- 747

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C  + C  A   +    +H     G +  +C+   C   F+    +  HH+ H
Sbjct: 748 ----PYSC--KECGNAFRLQAELTRHHIVHTGEKPYKCK--ECGKAFSVNSELTRHHRIH 799

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRC 374
                + C  C  A         H  Q +  SEE+ C
Sbjct: 800 TGEKPYQCKECGKAFIRSDQLTLH--QRNHISEEVLC 834



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 36/156 (23%), Positives = 57/156 (36%), Gaps = 11/156 (7%)

Query: 474 VHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMA 532
           +H + HA +  Y+C +C     +   L  H   H G +   C  C  A  R  +L+ H  
Sbjct: 206 LHPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHT 265

Query: 533 SQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHK 592
              H G     Y C  C    R    +  H+   H+ ++ + C  C         L  H+
Sbjct: 266 I--HAGERP--YECKECGKAFRLHYHLTEHQRI-HSGVKPYECKECGKAFSRVRDLRVHQ 320

Query: 593 RKAHGYVPGD-----QAWQLRYASQEPEGAMQGPTP 623
               G  P +     +A++L Y   E +    G  P
Sbjct: 321 TIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERP 356



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)

Query: 814 QAEALVLEGRVQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGA 873
           +A + V + RV   +  GE R + C  C    R    L  H R     R  P  C  CG 
Sbjct: 308 KAFSRVRDLRVHQTIHAGE-RPYECKECGKAFRLHYQLTEHQRIHTGER--PYECKVCGK 364

Query: 874 SFKQQRGLSTH 884
           +F+ QR +S H
Sbjct: 365 TFRVQRHISQH 375


>gi|134254457 zinc finger protein 665 [Homo sapiens]
          Length = 678

 Score =  225 bits (574), Expect = 2e-58
 Identities = 145/478 (30%), Positives = 196/478 (41%), Gaps = 38/478 (7%)

Query: 1170 HLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIP 1229
            H +C +CG    Q+  +  H+R+ H G KP+QC  C  + T R  L  HQ  HTG     
Sbjct: 177  HYKCDECGKVFSQNSRLTSHKRI-HTGEKPYQCNKCGKAFTVRSNLTIHQVIHTGEKPYK 235

Query: 1230 CSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACS 1289
            C+ C + F   S L  H+ R+H     + C  C  +      +T H    H G   + C 
Sbjct: 236  CNECGKVFSQPSNLAGHQ-RIHTGEKPYKCNECGKAFRAHSKLTTH-QVIHTGEKPYKCK 293

Query: 1290 QCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHT-- 1347
            +C   F+  + L  H  R H             T E P  C+ CG      +SL  H   
Sbjct: 294  ECGKCFTQNSHLASHR-RIH-------------TGEKPYKCNECGKAFSVRSSLTTHQTI 339

Query: 1348 RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEE 1405
                   +C  C + F     L +HRR       ++C  C  A      L KH +     
Sbjct: 340  HTGEKPYKCNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNLTKHQIIH--- 396

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
                          G+ P  C  C         L +H + H G + Y+C +C  +   R 
Sbjct: 397  -------------TGEKPFKCNECVKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRS 443

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T H  IHTGEKPY C+ C       S L  H  IH  E+ Y C ECG      +QL  
Sbjct: 444  SLTTHQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLAR 503

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLR 1585
            H   HTG KPY+C EC    +   +L +HQ T H   + + C  CGK F+    L  H R
Sbjct: 504  HWRVHTGEKPYKCNECGKAFSVHSSLTIHQ-TIHTGQKPYKCNDCGKVFRHNSYLAIHQR 562

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             H+  KPY CN C +AF   + L  H + HT   P+ C  C     Q   +  H R H
Sbjct: 563  IHTGEKPYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIH 620



 Score =  219 bits (559), Expect = 1e-56
 Identities = 156/550 (28%), Positives = 217/550 (39%), Gaps = 53/550 (9%)

Query: 1100 KGARFSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRR 1157
            +G  + C  C     Q   L +H+        +GE    C+ C       + L +HQ   
Sbjct: 174  RGKHYKCDECGKVFSQNSRLTSHK-----RIHTGEKPYQCNKCGKAFTVRSNLTIHQVIH 228

Query: 1158 HPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEA 1217
                    G +P+ +C +CG    Q   +  H+R+ H G KP++C  C  +     +L  
Sbjct: 229  -------TGEKPY-KCNECGKVFSQPSNLAGHQRI-HTGEKPYKCNECGKAFRAHSKLTT 279

Query: 1218 HQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVN 1277
            HQ  HTG     C  C + F  NS L  HR R+H     + C  C  +  +R  +T H  
Sbjct: 280  HQVIHTGEKPYKCKECGKCFTQNSHLASHR-RIHTGEKPYKCNECGKAFSVRSSLTTH-Q 337

Query: 1278 SCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLC 1337
            + H G   + C++C   F   + L +H  R H             T E P  C+ CG   
Sbjct: 338  TIHTGEKPYKCNECGKVFRHNSYLAKHR-RIH-------------TGEKPYKCNECGKAF 383

Query: 1338 PSPASLRGHT--RKQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERV 1393
               ++L  H          +C  C + F     L  HRR       +RC  C  A   R 
Sbjct: 384  SMHSNLTKHQIIHTGEKPFKCNECVKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRS 443

Query: 1394 GLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYK 1453
             L  H                     G+ P  C  C         L  H   H G + YK
Sbjct: 444  SLTTHQAIH----------------TGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYK 487

Query: 1454 CTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPEC 1513
            C +C  +     ++  H R+HTGEKPY C+ C  A +  S L  H  IH  ++ Y C +C
Sbjct: 488  CDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFSVHSSLTIHQTIHTGQKPYKCNDC 547

Query: 1514 GYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKA 1573
            G   +  + L  H   HTG KPY+C EC    +    L  HQ   H   + + C +CGK 
Sbjct: 548  GKVFRHNSYLAIHQRIHTGEKPYKCNECGKAFSVHSNLATHQVI-HTGEKPYKCNECGKV 606

Query: 1574 FKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQK 1633
            F     L  H R H+  KPY CN C +AF   + L  H   HT   P+ C  C     Q 
Sbjct: 607  FTQNSHLANHRRIHTGEKPYRCNECGKAFSVRSTLTTHMAVHTGDKPYKCNQCGKVFTQN 666

Query: 1634 FQVVKHVRRH 1643
              + KH R H
Sbjct: 667  SNLAKHRRIH 676



 Score =  187 bits (476), Expect = 6e-47
 Identities = 133/455 (29%), Positives = 181/455 (39%), Gaps = 67/455 (14%)

Query: 1166 GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGI 1225
            G +P+ +C +CG    Q+  +  HRR+ H G KP++C  C  + + R  L  HQ+ HTG 
Sbjct: 286  GEKPY-KCKECGKCFTQNSHLASHRRI-HTGEKPYKCNECGKAFSVRSSLTTHQTIHTGE 343

Query: 1226 GRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPA 1285
                C+ C + F  NS L  HR R+H     + C  C  +  +  ++T+H    H G   
Sbjct: 344  KPYKCNECGKVFRHNSYLAKHR-RIHTGEKPYKCNECGKAFSMHSNLTKH-QIIHTGEKP 401

Query: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRG 1345
            F C++C   F+  + L  H  R H             T E P  C  CG      +SL  
Sbjct: 402  FKCNECVKVFTQYSHLANHR-RIH-------------TGEKPYRCDECGKAFSVRSSLTT 447

Query: 1346 HT--RKQHPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKHYLE 1401
            H          +C  C + F     L  HR        ++C  C  A  +   L +H+  
Sbjct: 448  HQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRV 507

Query: 1402 QHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYST 1461
                              G+ P  C  C         L  H   H G + YKC DC    
Sbjct: 508  H----------------TGEKPYKCNECGKAFSVHSSLTIHQTIHTGQKPYKCNDCGKVF 551

Query: 1462 KNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVN 1521
            ++   +  H RIHTGEKPY C+ C  A +  S L  H  IH  E+ Y C ECG      +
Sbjct: 552  RHNSYLAIHQRIHTGEKPYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNS 611

Query: 1522 QLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLR 1581
             L  H   HTG KPY+C E                             CGKAF  R  L 
Sbjct: 612  HLANHRRIHTGEKPYRCNE-----------------------------CGKAFSVRSTLT 642

Query: 1582 THLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHT 1616
            TH+  H+  KPY CN C + F   + L  H   H+
Sbjct: 643  THMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIHS 677



 Score =  172 bits (436), Expect = 2e-42
 Identities = 118/437 (27%), Positives = 180/437 (41%), Gaps = 26/437 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F+  + L  H  +H  +   +C  C K FT  S L +H     GEK + 
Sbjct: 260 KPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKECGKCFTQNSHLASHRRIHTGEKPYK 319

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R++L  H  ++H          Y C  C + FR +  L +H + HT    
Sbjct: 320 CNECGKAFSVRSSLTTHQ-TIHTG-----EKPYKCNECGKVFRHNSYLAKHRRIHTGEK- 372

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C +  C  A        KH     G +  +C  + C  +F     +  H + H
Sbjct: 373 ----PYKCNE--CGKAFSMHSNLTKHQIIHTGEKPFKC--NECVKVFTQYSHLANHRRIH 424

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +     H+   H G +  +C  C            H G +H+ 
Sbjct: 425 TGEKPYRCDECGKAFSVRSSLTTHQAI-HTGEKPYKCNDCGKVFTQNSHLASHRG-IHSG 482

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  A +    L RH  +HTGEKP+KC  C       S L+ H   H+  K Y
Sbjct: 483 EKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFSVHSSLTIHQTIHTGQKPY 542

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C +CG V +   YL +H R H G+  Y+CN+C         L++H++ H G K   C  
Sbjct: 543 KCNDCGKVFRHNSYLAIHQRIHTGEKPYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNE 602

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C     + +    H+A+     T    Y C+ C      +  + +H    HT  + + C 
Sbjct: 603 CG----KVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRSTLTTH-MAVHTGDKPYKCN 657

Query: 577 LCDYRTFSNTTLLFHKR 593
            C      N+ L  H+R
Sbjct: 658 QCGKVFTQNSNLAKHRR 674



 Score =  153 bits (387), Expect = 1e-36
 Identities = 118/466 (25%), Positives = 175/466 (37%), Gaps = 42/466 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F + + L  H  +H  +   QC  C K FT +S L  H +   GEK + 
Sbjct: 176 KHYKCDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTIHQVIHTGEKPYK 235

Query: 221 CPLC---------------------HYSAVE-RNALNRHMASMHEDISNFYSDTYACPVC 258
           C  C                      Y   E   A   H       + +     Y C  C
Sbjct: 236 CNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKEC 295

Query: 259 REEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC 318
            + F  +  L  H + HT        P +C +  C  A   R +   H     G +  +C
Sbjct: 296 GKCFTQNSHLASHRRIHTGEK-----PYKCNE--CGKAFSVRSSLTTHQTIHTGEKPYKC 348

Query: 319 RHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCT 375
             + C  +F     +  H + H     + C  C  A S      KH+   H G +  +C 
Sbjct: 349 --NECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNLTKHQII-HTGEKPFKCN 405

Query: 376 FCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCD 435
            C    F   ++  +  ++H  EK ++C EC  A + +  L  H  +HTGEKP+KC  C 
Sbjct: 406 EC-VKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTHQAIHTGEKPYKCNDCG 464

Query: 436 FTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCH 495
                 S+L+ H   HS  K Y C ECG        L  H R H G+  Y+CN+C     
Sbjct: 465 KVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFS 524

Query: 496 RADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSR 554
               L+ H+  H G K   C  C     + +    ++A      T    Y C+ C     
Sbjct: 525 VHSSLTIHQTIHTGQKPYKCNDCG----KVFRHNSYLAIHQRIHTGEKPYKCNECGKAFS 580

Query: 555 HKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
               + +H+   HT  + + C  C      N+ L  H+R   G  P
Sbjct: 581 VHSNLATHQ-VIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKP 625



 Score =  147 bits (370), Expect = 1e-34
 Identities = 103/401 (25%), Positives = 153/401 (38%), Gaps = 62/401 (15%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC +CF + +HL  H  +H  +   +C  C K F+ +S L TH     GEK + 
Sbjct: 288 KPYKCKECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQTIHTGEKPYK 347

Query: 221 CPLCHYSAVERNALNRHMA-----------------SMHEDISNFY-----SDTYACPVC 258
           C  C       + L +H                   SMH +++           + C  C
Sbjct: 348 CNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNLTKHQIIHTGEKPFKCNEC 407

Query: 259 REEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC 318
            + F     L  H + HT        P RC  + C  A   R +   H     G +  +C
Sbjct: 408 VKVFTQYSHLANHRRIHTGEK-----PYRC--DECGKAFSVRSSLTTHQAIHTGEKPYKC 460

Query: 319 RHHSCPMLFATAEAMEAH---HKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCT 375
             + C  +F     + +H   H     + C  C  A S      +H +  H G +  +C 
Sbjct: 461 --NDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRV-HTGEKPYKCN 517

Query: 376 FC--PFATFNPVAYQD--HVG-----------------------KMHAHEKIHQCPECNF 408
            C   F+  + +      H G                       ++H  EK ++C EC  
Sbjct: 518 ECGKAFSVHSSLTIHQTIHTGQKPYKCNDCGKVFRHNSYLAIHQRIHTGEKPYKCNECGK 577

Query: 409 ATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKW 468
           A +    L  H ++HTGEKP+KC  C       S+L+ H   H+  K Y C ECG     
Sbjct: 578 AFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSV 637

Query: 469 KHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG 509
           +  L  HM  H GD  Y+CNQC     +   L+ H+  H G
Sbjct: 638 RSTLTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIHSG 678



 Score =  101 bits (252), Expect = 5e-21
 Identities = 64/224 (28%), Positives = 100/224 (44%), Gaps = 20/224 (8%)

Query: 390 HVGKMHAHEKI----------HQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCD--FT 437
           H GK++ + ++          ++C EC    +    L  H  +HTGEKP++C  C   FT
Sbjct: 157 HEGKIYEYNQVEKSPNNRGKHYKCDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFT 216

Query: 438 CRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRA 497
            R  S L+ H + H+  K Y C ECG V      L  H R H G+  Y+CN+C       
Sbjct: 217 VR--SNLTIHQVIHTGEKPYKCNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAH 274

Query: 498 DQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHK 556
            +L++H++ H G K   C+ C     + +    H+AS     T    Y C+ C      +
Sbjct: 275 SKLTTHQVIHTGEKPYKCKECG----KCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVR 330

Query: 557 QAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            ++ +H+   HT  + + C  C      N+ L  H+R   G  P
Sbjct: 331 SSLTTHQTI-HTGEKPYKCNECGKVFRHNSYLAKHRRIHTGEKP 373



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 28/89 (31%), Positives = 43/89 (48%)

Query: 1555 QETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALT 1614
            +++ +   + + C++CGK F     L +H R H+  KPY CN C +AF   + L  H + 
Sbjct: 168  EKSPNNRGKHYKCDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTIHQVI 227

Query: 1615 HTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            HT   P+ C  C     Q   +  H R H
Sbjct: 228  HTGEKPYKCNECGKVFSQPSNLAGHQRIH 256



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 49/212 (23%), Positives = 78/212 (36%), Gaps = 18/212 (8%)

Query: 155 GTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLREL 214
           G  S  K + C EC + F + + L  H  +H  +   +C  C K F+  S L  H     
Sbjct: 478 GIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFSVHSSLTIHQTIHT 537

Query: 215 GEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKS 274
           G+K + C  C    V R+  N ++A +H+ I +     Y C  C + F +   L  H   
Sbjct: 538 GQKPYKCNDC--GKVFRH--NSYLA-IHQRI-HTGEKPYKCNECGKAFSVHSNLATHQVI 591

Query: 275 HTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAME 334
           HT        P +C +  C            H +   G +   C  + C   F+    + 
Sbjct: 592 HTGEK-----PYKCNE--CGKVFTQNSHLANHRRIHTGEKPYRC--NECGKAFSVRSTLT 642

Query: 335 AH---HKSHYAFHCPHCDFACSNKHLFRKHKK 363
            H   H     + C  C    +      KH++
Sbjct: 643 THMAVHTGDKPYKCNQCGKVFTQNSNLAKHRR 674



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C  + R    L +H R  TG     +P  C ECG +F     L+TH
Sbjct: 540 KPYKCNDCGKVFRHNSYLAIHQRIHTG----EKPYKCNECGKAFSVHSNLATH 588


>gi|25014093 zinc finger protein 585B [Homo sapiens]
          Length = 769

 Score =  225 bits (573), Expect = 3e-58
 Identities = 158/537 (29%), Positives = 227/537 (42%), Gaps = 50/537 (9%)

Query: 1132 SGELH--CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQH 1189
            +GE H  C+ C       + L++HQK          G R ++ C +CG    Q   +  H
Sbjct: 237  TGERHHECTDCGKAFTQKSTLKIHQKIH-------TGERSYI-CIECGQAFIQKTQLIAH 288

Query: 1190 RRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLR 1249
            RR+ H G KP++C  C  S   + +L+ HQ  HT +    C+   + F  NS L  H  +
Sbjct: 289  RRI-HSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITHE-K 346

Query: 1250 VHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRH 1309
            +  +  +  C  C  +   R ++  H    H G   + CS C   F+ ++AL  H     
Sbjct: 347  IQSREKSSICTECGKAFTYRSELIIH-QRIHTGEKPYECSDCGRAFTQKSALTVHQRIHT 405

Query: 1310 PEP--------------AQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTR---KQHP 1352
             E               A         T E P  C  CG L  S + L  H R    + P
Sbjct: 406  GEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKP 465

Query: 1353 RLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAAV 1410
             + C  C +AF +R  L  H++      S+ C  C  A  +R  L+ H   Q   T    
Sbjct: 466  YV-CNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITH---QRIHT---- 517

Query: 1411 AASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWH 1470
                     G+ P  C  C      +  L+ H K H G R Y+C +C  +   +  +  H
Sbjct: 518  ---------GEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHECGKAFNQKSILIVH 568

Query: 1471 SRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKH 1530
             +IHTGEKPY C  C  A    S    H RIH  E+ Y C +CG      +QL  H   H
Sbjct: 569  QKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVH 628

Query: 1531 TGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEA 1590
            TG KPY C EC    +    L  HQ+T H   + ++C +CGK F+ +  L TH R H+  
Sbjct: 629  TGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECGKTFRQKSELITHHRIHTGE 687

Query: 1591 KPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
            KPY C+ C ++F   + L+ H   HT   P+ C  C      +  + KH   H  D+
Sbjct: 688  KPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDK 744



 Score =  182 bits (461), Expect = 3e-45
 Identities = 130/457 (28%), Positives = 191/457 (41%), Gaps = 48/457 (10%)

Query: 1137 CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEG 1196
            C+ C       + L +HQ+          G +P+ +C DCG    Q   +  H+R+ H G
Sbjct: 356  CTECGKAFTYRSELIIHQRIH-------TGEKPY-ECSDCGRAFTQKSALTVHQRI-HTG 406

Query: 1197 VKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPT 1256
             K + C  C  +  R+  L  HQ  HTG     C  C + F + S+L +H+ R+H     
Sbjct: 407  EKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHK-RIHTGEKP 465

Query: 1257 HFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPA 1316
            + C  C  +   R ++  H  + H G  ++ CS+C   F+  + L  H  R H       
Sbjct: 466  YVCNKCGKAFTNRSNLITHQKT-HTGEKSYICSKCGKAFTQRSDLITHQ-RIH------- 516

Query: 1317 PGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP---RLECGACQEAFPSRLALDEHR 1373
                  T E P  C+ CG      ++L  H +K H    + EC  C +AF  +  L  H+
Sbjct: 517  ------TGEKPYECNTCGKAFTQKSNLNIH-QKIHTGERQYECHECGKAFNQKSILIVHQ 569

Query: 1374 RQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFC--DF 1431
            +  H   +  +C    R  +        Q   T             G+ P  C  C   F
Sbjct: 570  KI-HTGEKPYVCTECGRAFIRKSNFITHQRIHT-------------GEKPYECSDCGKSF 615

Query: 1432 TCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACAD 1491
            T + QL++  H   H G + Y C +C  +   R  ++ H + HTGEKPY C  C      
Sbjct: 616  TSKSQLLV--HQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQ 673

Query: 1492 PSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADAL 1551
             S L  H RIH  E+ Y C +CG      +QL+ H   HTG KPY C EC    +    L
Sbjct: 674  KSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNL 733

Query: 1552 RVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHS 1588
              HQ T H   + + C  CGK F  + +   H   H+
Sbjct: 734  NKHQTT-HTGDKPYKCGICGKGFVQKSVFSVHQSSHA 769



 Score =  176 bits (446), Expect = 2e-43
 Identities = 138/493 (27%), Positives = 193/493 (39%), Gaps = 40/493 (8%)

Query: 1173 CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
            C +CG    Q      H++  H   KP +C  C  S  +   L  H   HTG     CS 
Sbjct: 160  CIECGRAFVQKPEFITHQKT-HMREKPPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSE 218

Query: 1233 CPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCE 1292
            C + F  NS L +H  ++H     H C  C  +   +  +  H    H G  ++ C +C 
Sbjct: 219  CGKGFPYNSDLSIHE-KIHTGERHHECTDCGKAFTQKSTLKIH-QKIHTGERSYICIECG 276

Query: 1293 AQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHP 1352
              F  +T L  H  R H             + E P  C+ CG    S + L+ H R  H 
Sbjct: 277  QAFIQKTQLIAHR-RIH-------------SGEKPYECNNCGKSFISKSQLQVHQRV-HT 321

Query: 1353 RLECGACQE-----AFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETS 1407
            R++   C E     +  S L   E  + +  S  C  C  A   R  L+ H   Q   T 
Sbjct: 322  RVKPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIH---QRIHT- 377

Query: 1408 AAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKI 1467
                        G+ P  C  C      +  L  H + H G + Y C  C  +   +  +
Sbjct: 378  ------------GEKPYECSDCGRAFTQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHL 425

Query: 1468 TWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHM 1527
              H  IHTGEKPY C  C       S+L  H RIH  E+ Y+C +CG      + L  H 
Sbjct: 426  ITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQ 485

Query: 1528 TKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKH 1587
              HTG K Y C +C     +   L  HQ   H   + + C  CGKAF  +  L  H + H
Sbjct: 486  KTHTGEKSYICSKCGKAFTQRSDLITHQRI-HTGEKPYECNTCGKAFTQKSNLNIHQKIH 544

Query: 1588 SEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ 1647
            +  + Y C+ C +AF   + L  H   HT   P+ C  C     +K   + H R H  ++
Sbjct: 545  TGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEK 604

Query: 1648 ADPNQGVGKDPTT 1660
                   GK  T+
Sbjct: 605  PYECSDCGKSFTS 617



 Score =  168 bits (426), Expect = 4e-41
 Identities = 124/456 (27%), Positives = 185/456 (40%), Gaps = 26/456 (5%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQG-AQRLEGDVVSGTESLFKTHMCPECKRCF 172
           G+  +   N+   EK  +++ S    + G+    R E  +     +  K + C +C R F
Sbjct: 332 GKVFSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGRAF 391

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++ L  H  +H  + S  C  C   F  K+ L TH +   GEK + C  C      ++
Sbjct: 392 TQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKS 451

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L+ H   +H          Y C  C + F     L  H K+HT   +            
Sbjct: 452 QLHVHKR-IHTG-----EKPYVCNKCGKAFTNRSNLITHQKTHTGEKSY-------ICSK 498

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C  A   R   I H +   G +  EC  ++C   F     +  H K H     + C  C 
Sbjct: 499 CGKAFTQRSDLITHQRIHTGEKPYEC--NTCGKAFTQKSNLNIHQKIHTGERQYECHECG 556

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFA 409
            A + K +   H+K  H G +   CT C  A      +  H  ++H  EK ++C +C  +
Sbjct: 557 KAFNQKSILIVHQKI-HTGEKPYVCTECGRAFIRKSNFITHQ-RIHTGEKPYECSDCGKS 614

Query: 410 TAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWK 469
              K  L+ H  +HTGEKP+ C  C       S LSKH  TH+  K Y+C+ECG   + K
Sbjct: 615 FTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQK 674

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
             L  H R H G+  Y+C+ C     +  QL  H+  H G K  +C  C  A   +  L 
Sbjct: 675 SELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLN 734

Query: 529 KHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHEN 564
           KH  +  H G     Y C  C      K     H++
Sbjct: 735 KHQTT--HTGDKP--YKCGICGKGFVQKSVFSVHQS 766



 Score =  151 bits (382), Expect = 5e-36
 Identities = 118/443 (26%), Positives = 178/443 (40%), Gaps = 33/443 (7%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K ++C EC R F ++   + H   H  +   +C  C K F   S L  H     GEK + 
Sbjct: 156 KLYVCIECGRAFVQKPEFITHQKTHMREKPPKCNECGKSFFQVSSLFRHHRIHTGEKLYE 215

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C       + L     S+HE I +     + C  C + F     LK H K HT   +
Sbjct: 216 CSECGKGFPYNSDL-----SIHEKI-HTGERHHECTDCGKAFTQKSTLKIHQKIHTGERS 269

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
                  C +  C  A   +   I H +   G +  EC  ++C   F +   ++ H + H
Sbjct: 270 -----YICIE--CGQAFIQKTQLIAHRRIHSGEKPYEC--NNCGKSFISKSQLQVHQRVH 320

Query: 341 ---YAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHV---GKM 394
                + C       SN      H+K        + CT C  A      Y+  +    ++
Sbjct: 321 TRVKPYICTEYGKVFSNNSNLITHEKIQSREKSSI-CTECGKA----FTYRSELIIHQRI 375

Query: 395 HAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNT 454
           H  EK ++C +C  A   K  L  H  +HTGEK + C  C       ++L  H + H+  
Sbjct: 376 HTGEKPYECSDCGRAFTQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGE 435

Query: 455 KDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLM 513
           K Y C  CG +   K  L VH R H G+  Y CN+C         L +H+  H G KS +
Sbjct: 436 KPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSYI 495

Query: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C  C  A  ++ +L  H   + H G     Y C+ C      K  +  H+   HT  R++
Sbjct: 496 CSKCGKAFTQRSDLITH--QRIHTGEKP--YECNTCGKAFTQKSNLNIHQKI-HTGERQY 550

Query: 574 HCALCDYRTFSNTTLLFHKRKAH 596
            C  C  + F+  ++L   +K H
Sbjct: 551 ECHECG-KAFNQKSILIVHQKIH 572



 Score =  149 bits (377), Expect = 2e-35
 Identities = 117/444 (26%), Positives = 175/444 (39%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F   + L  H  +H  +   +C +C K FT KS LK H     GE+++ 
Sbjct: 212 KLYECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYI 271

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  + +++  L  H   +H          Y C  C + F     L+ H + HT    
Sbjct: 272 CIECGQAFIQKTQLIAH-RRIHSG-----EKPYECNNCGKSFISKSQLQVHQRVHTRVK- 324

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C + G  ++  +    I H K     ++  C    C   F     +  H + H
Sbjct: 325 ----PYICTEYGKVFS--NNSNLITHEKIQSREKSSICT--ECGKAFTYRSELIIHQRIH 376

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A + K     H++  H G +   C  C  A         H   +H  
Sbjct: 377 TGEKPYECSDCGRAFTQKSALTVHQRI-HTGEKSYICMKCGLAFIRKAHLITH-QIIHTG 434

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C  C      K  L  H  +HTGEKP+ C  C     + S L  H  TH+  K Y
Sbjct: 435 EKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSY 494

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
           +C++CG     +  L  H R H G+  Y+CN C     +   L+ H+  H G +   C  
Sbjct: 495 ICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHE 554

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C  A  +K  L  H   + H G     Y C  C      K   ++H+   HT  + + C+
Sbjct: 555 CGKAFNQKSILIVH--QKIHTGEKP--YVCTECGRAFIRKSNFITHQRI-HTGEKPYECS 609

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
            C     S + LL H+    G  P
Sbjct: 610 DCGKSFTSKSQLLVHQPVHTGEKP 633



 Score =  147 bits (372), Expect = 7e-35
 Identities = 117/451 (25%), Positives = 175/451 (38%), Gaps = 34/451 (7%)

Query: 161 KTHM------CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLREL 214
           KTHM      C EC + F + + L  H  +H  +   +C  C K F   S L  H     
Sbjct: 178 KTHMREKPPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHT 237

Query: 215 GEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKS 274
           GE+ H C  C  +  +++ L  H   +H         +Y C  C + F     L  H + 
Sbjct: 238 GERHHECTDCGKAFTQKSTLKIHQ-KIHTG-----ERSYICIECGQAFIQKTQLIAHRRI 291

Query: 275 HTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHH----SCPMLFATA 330
           H+        P  C    C  +   +     H +    V+   C  +    S      T 
Sbjct: 292 HSGEK-----PYEC--NNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITH 344

Query: 331 EAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDH 390
           E +++  KS     C  C  A + +     H++  H G +   C+ C  A     A   H
Sbjct: 345 EKIQSREKSSI---CTECGKAFTYRSELIIHQRI-HTGEKPYECSDCGRAFTQKSALTVH 400

Query: 391 VGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLT 450
             ++H  EK + C +C  A   K  LI H ++HTGEKP+KC  C       S L  H   
Sbjct: 401 -QRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRI 459

Query: 451 HSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG- 509
           H+  K Y+C +CG     +  L  H + H G+  Y C++C     +   L +H+  H G 
Sbjct: 460 HTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGE 519

Query: 510 KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTR 569
           K   C  C  A  +K  L  H   + H G     Y CH C      K  ++ H+   HT 
Sbjct: 520 KPYECNTCGKAFTQKSNLNIH--QKIHTGERQ--YECHECGKAFNQKSILIVHQKI-HTG 574

Query: 570 LREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + + C  C       +  + H+R   G  P
Sbjct: 575 EKPYVCTECGRAFIRKSNFITHQRIHTGEKP 605



 Score =  141 bits (356), Expect = 5e-33
 Identities = 114/431 (26%), Positives = 168/431 (38%), Gaps = 48/431 (11%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELH--CSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  +  Q+ AL  HQ        +GE    C  C         L  HQ       
Sbjct: 382  YECSDCGRAFTQKSALTVHQ-----RIHTGEKSYICMKCGLAFIRKAHLITHQIIH---- 432

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +CG CG        +  H+R+ H G KP+ C  C  + T R  L  HQ  
Sbjct: 433  ---TGEKPY-KCGHCGKLFTSKSQLHVHKRI-HTGEKPYVCNKCGKAFTNRSNLITHQKT 487

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     CS C + F   S L  H+ R+H     + C  C  +   + ++  H    H 
Sbjct: 488  HTGEKSYICSKCGKAFTQRSDLITHQ-RIHTGEKPYECNTCGKAFTQKSNLNIH-QKIHT 545

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C +C   F+ ++ L  H                  T E P  C+ CG      +
Sbjct: 546  GERQYECHECGKAFNQKSILIVH--------------QKIHTGEKPYVCTECGRAFIRKS 591

Query: 1342 SLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHY 1399
            +   H R        EC  C ++F S+  L  H+   H   +  +C    +   G  +  
Sbjct: 592  NFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQ-PVHTGEKPYVCAECGKAFSG--RSN 648

Query: 1400 LEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAY 1459
            L +H++T             G+ P  C  C  T R +  L  H + H G + Y+C+DC  
Sbjct: 649  LSKHQKTHT-----------GEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGK 697

Query: 1460 STKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKW 1519
            S   + ++  H RIHTGEKPY C  C  A ++ S L  H   H  ++ Y C  CG     
Sbjct: 698  SFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPYKCGICGKGFVQ 757

Query: 1520 VNQLKYHMTKH 1530
             +    H + H
Sbjct: 758  KSVFSVHQSSH 768



 Score =  140 bits (354), Expect = 8e-33
 Identities = 104/377 (27%), Positives = 144/377 (38%), Gaps = 46/377 (12%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K+++C +C   F ++ HL+ H  +H  +   +C +C K FTSKS+L  H     GEK + 
Sbjct: 408 KSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYV 467

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R+ L  H  +   + S      Y C  C + F     L  H + HT    
Sbjct: 468 CNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHTGEK- 520

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C    C  A   +     H K   G R  EC  H C   F     +  H K H
Sbjct: 521 ----PYEC--NTCGKAFTQKSNLNIHQKIHTGERQYEC--HECGKAFNQKSILIVHQKIH 572

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQD--HVG- 392
                + C  C  A   K  F  H++  H G +   C+ C   F + + +      H G 
Sbjct: 573 TGEKPYVCTECGRAFIRKSNFITHQRI-HTGEKPYECSDCGKSFTSKSQLLVHQPVHTGE 631

Query: 393 ----------------------KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
                                 K H  EK + C EC      K  LI H  +HTGEKP++
Sbjct: 632 KPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYE 691

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C  +    S L  H   H+  K Y+C ECG     +  L  H   H GD  Y+C  C
Sbjct: 692 CSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPYKCGIC 751

Query: 491 SYRCHRADQLSSHKLRH 507
                +    S H+  H
Sbjct: 752 GKGFVQKSVFSVHQSSH 768



 Score =  137 bits (344), Expect = 1e-31
 Identities = 95/323 (29%), Positives = 134/323 (41%), Gaps = 20/323 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K ++C +C + F  R++L+ H   H  + S  C  C K FT +S L TH     GEK + 
Sbjct: 464 KPYVCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYE 523

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ LN H   +H          Y C  C + F     L  H K HT    
Sbjct: 524 CNTCGKAFTQKSNLNIHQ-KIHTG-----ERQYECHECGKAFNQKSILIVHQKIHTGEK- 576

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAH---H 337
               P  C +  C  A   +  FI H +   G +  EC    C   F +   +  H   H
Sbjct: 577 ----PYVCTE--CGRAFIRKSNFITHQRIHTGEKPYECS--DCGKSFTSKSQLLVHQPVH 628

Query: 338 KSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A S +    KH+K  H G +   C+ C   TF   +      ++H  
Sbjct: 629 TGEKPYVCAECGKAFSGRSNLSKHQKT-HTGEKPYICSECG-KTFRQKSELITHHRIHTG 686

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C +C  +   K  L  H  +HTGEKP+ C  C     + S L+KH  TH+  K Y
Sbjct: 687 EKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPY 746

Query: 458 MCTECGYVTKWKHYLRVHMRKHA 480
            C  CG     K    VH   HA
Sbjct: 747 KCGICGKGFVQKSVFSVHQSSHA 769



 Score =  134 bits (337), Expect = 7e-31
 Identities = 80/248 (32%), Positives = 116/248 (46%), Gaps = 2/248 (0%)

Query: 1420 GQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKP 1479
            G+    C  C     +   L  H K H G R ++CTDC  +   +  +  H +IHTGE+ 
Sbjct: 210  GEKLYECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERS 269

Query: 1480 YHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCP 1539
            Y C  C  A    ++L  H RIH  E+ Y C  CG      +QL+ H   HT +KPY C 
Sbjct: 270  YICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYICT 329

Query: 1540 ECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCH 1599
            E     +    L  H++ + RE ++ +C +CGKAF  R  L  H R H+  KPY C+ C 
Sbjct: 330  EYGKVFSNNSNLITHEKIQSRE-KSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCG 388

Query: 1600 RAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPT 1659
            RAF   + L  H   HT    + C  C     +K  ++ H   H  ++       GK  T
Sbjct: 389  RAFTQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFT 448

Query: 1660 TPT-VHLH 1666
            + + +H+H
Sbjct: 449  SKSQLHVH 456



 Score =  120 bits (301), Expect = 1e-26
 Identities = 64/193 (33%), Positives = 97/193 (50%), Gaps = 3/193 (1%)

Query: 1431 FTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACA 1490
            FT + Q  +  H+K   G +LY C +C  +   + +   H + H  EKP  C+ C  +  
Sbjct: 139  FTWKSQFKV--HLKVPTGEKLYVCIECGRAFVQKPEFITHQKTHMREKPPKCNECGKSFF 196

Query: 1491 DPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADA 1550
              S L  H RIH  E+ Y C ECG    + + L  H   HTG + ++C +C     +   
Sbjct: 197  QVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKST 256

Query: 1551 LRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRH 1610
            L++HQ+  H   R+++C +CG+AF  +  L  H R HS  KPY CN C ++F   + L+ 
Sbjct: 257  LKIHQKI-HTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQV 315

Query: 1611 HALTHTDRHPFFC 1623
            H   HT   P+ C
Sbjct: 316  HQRVHTRVKPYIC 328



 Score =  115 bits (289), Expect = 3e-25
 Identities = 98/368 (26%), Positives = 139/368 (37%), Gaps = 45/368 (12%)

Query: 261 EFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRH 320
           EF  S   K   K H      E L + C +  C  A   +  FI H K     +  +C  
Sbjct: 134 EFGKSFTWKSQFKVHLKVPTGEKLYV-CIE--CGRAFVQKPEFITHQKTHMREKPPKC-- 188

Query: 321 HSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC 377
           + C   F    ++  HH+ H     + C  C            H+K  H G     CT C
Sbjct: 189 NECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKI-HTGERHHECTDC 247

Query: 378 PFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFT 437
             A       + H  K+H  E+ + C EC  A   K  LI H  +H+GEKP++C  C  +
Sbjct: 248 GKAFTQKSTLKIHQ-KIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKS 306

Query: 438 CRDVSYLSKHMLTHSNTKDYM----------------------------CTECGYVTKWK 469
               S L  H   H+  K Y+                            CTECG    ++
Sbjct: 307 FISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECGKAFTYR 366

Query: 470 HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQ 528
             L +H R H G+  Y+C+ C     +   L+ H+  H G KS +C  C  A  RK  L 
Sbjct: 367 SELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLI 426

Query: 529 KHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTL 588
            H     H G     Y C +C      K  +  H+   HT  + + C  C  + F+N + 
Sbjct: 427 THQII--HTGEKP--YKCGHCGKLFTSKSQLHVHKRI-HTGEKPYVCNKCG-KAFTNRSN 480

Query: 589 LFHKRKAH 596
           L   +K H
Sbjct: 481 LITHQKTH 488



 Score =  103 bits (257), Expect = 1e-21
 Identities = 62/204 (30%), Positives = 89/204 (43%), Gaps = 9/204 (4%)

Query: 1444 KGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHK 1503
            K + G + Y+C +   S   + +   H ++ TGEK Y C  C  A         H + H 
Sbjct: 122  KIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFVQKPEFITHQKTHM 181

Query: 1504 EERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPEC----EYCTNRADALRVHQETRH 1559
             E+   C ECG     V+ L  H   HTG K Y+C EC     Y ++ +   ++H   RH
Sbjct: 182  REKPPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHTGERH 241

Query: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRH 1619
             E     C  CGKAF  +  L+ H + H+  + Y+C  C +AF     L  H   H+   
Sbjct: 242  HE-----CTDCGKAFTQKSTLKIHQKIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEK 296

Query: 1620 PFFCRLCNYKAKQKFQVVKHVRRH 1643
            P+ C  C      K Q+  H R H
Sbjct: 297  PYECNNCGKSFISKSQLQVHQRVH 320



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 59/241 (24%), Positives = 98/241 (40%), Gaps = 36/241 (14%)

Query: 382 FNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPH------------ 429
           + P + QD   K+++ EK ++C E   +   K     H+ + TGEK +            
Sbjct: 113 YKPASSQDQ--KIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFVQK 170

Query: 430 ----------------KCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLR 473
                           KC  C  +   VS L +H   H+  K Y C+ECG    +   L 
Sbjct: 171 PEFITHQKTHMREKPPKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLS 230

Query: 474 VHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMA 532
           +H + H G+  ++C  C     +   L  H+  H G +S +C  C  A  +K +L  H  
Sbjct: 231 IHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYICIECGQAFIQKTQLIAH-- 288

Query: 533 SQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHK 592
            + H G     Y C+ C      K  +  H+   HTR++ + C        +N+ L+ H+
Sbjct: 289 RRIHSGEKP--YECNNCGKSFISKSQLQVHQRV-HTRVKPYICTEYGKVFSNNSNLITHE 345

Query: 593 R 593
           +
Sbjct: 346 K 346



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I    + ++C HC  +   +  L++H R  TG     +P +C +CG +F  +  L TH
Sbjct: 430 IIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTG----EKPYVCNKCGKAFTNRSNLITH 484



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 824 VQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLST 883
           V   V  GE + + C  C         L+ H +T      +P +C ECG +F+Q+  L T
Sbjct: 623 VHQPVHTGE-KPYVCAECGKAFSGRSNLSKHQKT--HTGEKPYICSECGKTFRQKSELIT 679

Query: 884 H 884
           H
Sbjct: 680 H 680


>gi|24307875 zinc finger protein 33B [Homo sapiens]
          Length = 778

 Score =  223 bits (569), Expect = 9e-58
 Identities = 142/478 (29%), Positives = 199/478 (41%), Gaps = 38/478 (7%)

Query: 1170 HLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIP 1229
            H +C +CG    +   + +H+R+ H G K  QC  C  +   +  L  HQ  HTG     
Sbjct: 328  HFECNECGKAFWEKSHLTRHQRV-HTGEKHFQCNQCGKTFWEKSNLTKHQRSHTGEKPFE 386

Query: 1230 CSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACS 1289
            C+ C + F   S L LH+ R H     + C  C  + Y + D+T+H  + H G   + C 
Sbjct: 387  CNECGKAFSHKSALTLHQ-RTHTGEKPYQCNACGKTFYQKSDLTKHQRT-HTGQKPYECY 444

Query: 1290 QCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRK 1349
            +C   F   + L  H  R H             T E P  C  CG      + L  H R 
Sbjct: 445  ECGKSFCMNSHLTVHQ-RTH-------------TGEKPFECLECGKSFCQKSHLTQHQRT 490

Query: 1350 Q--HPRLECGACQEAFPSRLALDEHR--RQQHFSHRCQLCDFAARERVGLVKHYLEQHEE 1405
                   EC AC + F  +  L  H+        + C  C      +   +K  L  H+ 
Sbjct: 491  HIGDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECG-----KTFCLKSDLTIHQR 545

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T             G+ P  CP C     H+  L  H + H G + Y+C +C     N+ 
Sbjct: 546  THT-----------GEKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKS 594

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
             +T H+R HTGEKPY C+ C       S+L  H RIH  E+ Y C ECG      + L  
Sbjct: 595  YLTKHNRTHTGEKPYECNECGKTFCQKSQLTQHQRIHIGEKPYECNECGKAFCHKSALIV 654

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLR 1585
            H   HT  KPY+C EC         L +H E +H   + + C +CGK+F  +  L  H R
Sbjct: 655  HQRTHTQEKPYKCNECGKSFCVKSGLILH-ERKHTGEKPYECNECGKSFSHKSSLTVHHR 713

Query: 1586 KHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
             H+  K   CN C + F   + L  H  +HT   P+ C  C     QK  ++ H R H
Sbjct: 714  AHTGEKSCQCNECGKIFYRKSDLAKHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRTH 771



 Score =  199 bits (506), Expect = 2e-50
 Identities = 149/495 (30%), Positives = 204/495 (41%), Gaps = 48/495 (9%)

Query: 1170 HLQCGDCG-FTCKQSRCMQQHRRLKHEGV--KPHQCPFCDFSTTRRYRLEAHQSRHTGIG 1226
            H +  DC  F C +S         KH+GV  K + C     +  R+  L   Q    G  
Sbjct: 274  HYEFSDCEKFLCVKSTLS------KHDGVPVKHYDCGESGNNFRRKLCLSQLQKGDKGEK 327

Query: 1227 RIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAF 1286
               C+ C + F   S L  H+ RVH       C  C  + + + ++T+H  S H G   F
Sbjct: 328  HFECNECGKAFWEKSHLTRHQ-RVHTGEKHFQCNQCGKTFWEKSNLTKHQRS-HTGEKPF 385

Query: 1287 ACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGH 1346
             C++C   FS ++AL  H  R H             T E P  C+ CG      + L  H
Sbjct: 386  ECNECGKAFSHKSALTLHQ-RTH-------------TGEKPYQCNACGKTFYQKSDLTKH 431

Query: 1347 TRK---QHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLE 1401
             R    Q P  EC  C ++F     L  H+R         C  C  +  +     K +L 
Sbjct: 432  QRTHTGQKP-YECYECGKSFCMNSHLTVHQRTHTGEKPFECLECGKSFCQ-----KSHLT 485

Query: 1402 QHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYST 1461
            QH+ T             G  P  C  C  T  H+ VL  H   H G + Y+C +C  + 
Sbjct: 486  QHQRTHI-----------GDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECGKTF 534

Query: 1462 KNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVN 1521
              +  +T H R HTGEKP+ C  C    +  S L  H R H  E+ Y C ECG      +
Sbjct: 535  CLKSDLTIHQRTHTGEKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKS 594

Query: 1522 QLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLR 1581
             L  H   HTG KPY+C EC     +   L  HQ   H   + + C +CGKAF  +  L 
Sbjct: 595  YLTKHNRTHTGEKPYECNECGKTFCQKSQLTQHQRI-HIGEKPYECNECGKAFCHKSALI 653

Query: 1582 THLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVR 1641
             H R H++ KPY CN C ++F   +GL  H   HT   P+ C  C      K  +  H R
Sbjct: 654  VHQRTHTQEKPYKCNECGKSFCVKSGLILHERKHTGEKPYECNECGKSFSHKSSLTVHHR 713

Query: 1642 RHHPDQADPNQGVGK 1656
             H  +++      GK
Sbjct: 714  AHTGEKSCQCNECGK 728



 Score =  177 bits (448), Expect = 1e-43
 Identities = 123/440 (27%), Positives = 177/440 (40%), Gaps = 26/440 (5%)

Query: 165 CPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLC 224
           C EC + F +++HL  H  +H  +   QC  C K F  KS L  H     GEK   C  C
Sbjct: 331 CNECGKAFWEKSHLTRHQRVHTGEKHFQCNQCGKTFWEKSNLTKHQRSHTGEKPFECNEC 390

Query: 225 HYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPL 284
             +   ++AL  H  +   +        Y C  C + F     L +H ++HT        
Sbjct: 391 GKAFSHKSALTLHQRTHTGE------KPYQCNACGKTFYQKSDLTKHQRTHTGQK----- 439

Query: 285 PLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA-- 342
           P  C++ G S+          H +   G +  EC    C   F     +  H ++H    
Sbjct: 440 PYECYECGKSFCMNSHLTV--HQRTHTGEKPFECLE--CGKSFCQKSHLTQHQRTHIGDK 495

Query: 343 -FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIH 401
            + C  C     +K +  +H+   H G +   C  C   TF   +      + H  EK  
Sbjct: 496 PYECNACGKTFYHKSVLTRHQII-HTGLKPYECYECG-KTFCLKSDLTIHQRTHTGEKPF 553

Query: 402 QCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTE 461
            CPEC    +HK  L +H   HTGEKP++C  C     + SYL+KH  TH+  K Y C E
Sbjct: 554 ACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNE 613

Query: 462 CGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYR-CHRADQLSSHKLRHQGKSLMCEVCAFA 520
           CG     K  L  H R H G+  Y+CN+C    CH++  +   +   Q K   C  C  +
Sbjct: 614 CGKTFCQKSQLTQHQRIHIGEKPYECNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKS 673

Query: 521 CKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDY 580
              K  L  H   + H G     Y C+ C     HK ++  H    HT  +   C  C  
Sbjct: 674 FCVKSGLILH--ERKHTGEKP--YECNECGKSFSHKSSLTVHHRA-HTGEKSCQCNECGK 728

Query: 581 RTFSNTTLLFHKRKAHGYVP 600
             +  + L  H+R   G  P
Sbjct: 729 IFYRKSDLAKHQRSHTGEKP 748



 Score =  170 bits (430), Expect = 1e-41
 Identities = 118/434 (27%), Positives = 176/434 (40%), Gaps = 51/434 (11%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K   C +C + F ++++L +H   H  +   +C  C K F+ KS L  H     GEK + 
Sbjct: 355 KHFQCNQCGKTFWEKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQ 414

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +  +++ L +H        ++     Y C  C + F ++  L  H ++HT    
Sbjct: 415 CNACGKTFYQKSDLTKHQR------THTGQKPYECYECGKSFCMNSHLTVHQRTHTGEK- 467

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETH-GVRAVEC--------------RH----- 320
               P  C + G S+    +K+ +   + TH G +  EC              RH     
Sbjct: 468 ----PFECLECGKSFC---QKSHLTQHQRTHIGDKPYECNACGKTFYHKSVLTRHQIIHT 520

Query: 321 -------HSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSE 370
                  + C   F     +  H ++H     F CP C    S+K    +H +  H G +
Sbjct: 521 GLKPYECYECGKTFCLKSDLTIHQRTHTGEKPFACPECGKFFSHKSTLSQHYRT-HTGEK 579

Query: 371 ELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHK 430
              C  C    +N  +Y     + H  EK ++C EC      K  L +H  +H GEKP++
Sbjct: 580 PYECHECGKIFYNK-SYLTKHNRTHTGEKPYECNECGKTFCQKSQLTQHQRIHIGEKPYE 638

Query: 431 CELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQC 490
           C  C       S L  H  TH+  K Y C ECG     K  L +H RKH G+  Y+CN+C
Sbjct: 639 CNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLILHERKHTGEKPYECNEC 698

Query: 491 SYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYC 549
                    L+ H   H G KS  C  C     RK +L KH  S  H G     Y C+ C
Sbjct: 699 GKSFSHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSDLAKHQRS--HTGEKP--YECNTC 754

Query: 550 SYQSRHKQAVLSHE 563
                 K  ++ H+
Sbjct: 755 RKTFSQKSNLIVHQ 768



 Score =  164 bits (415), Expect = 7e-40
 Identities = 123/445 (27%), Positives = 173/445 (38%), Gaps = 55/445 (12%)

Query: 1207 FSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSG 1266
            F+T +R   E +   +   GR  C S        S L  H+  +     +H+    ++S 
Sbjct: 234  FNTRKRENAEENNCDYNEFGRTFCDS--------SSLLFHQ--IPPSKDSHY----EFSD 279

Query: 1267 YLRHDITRHVNSCHQGTPA--FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETT 1324
              +    +   S H G P   + C +    F  +  L Q                  +  
Sbjct: 280  CEKFLCVKSTLSKHDGVPVKHYDCGESGNNFRRKLCLSQL--------------QKGDKG 325

Query: 1325 EGPLHCSRCGLLCPSPASL----RGHTRKQHPRLECGACQEAFPSRLALDEHRRQQ--HF 1378
            E    C+ CG      + L    R HT ++H   +C  C + F  +  L +H+R      
Sbjct: 326  EKHFECNECGKAFWEKSHLTRHQRVHTGEKH--FQCNQCGKTFWEKSNLTKHQRSHTGEK 383

Query: 1379 SHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLV 1438
               C  C  A   +  L  H   Q   T             G+ P  C  C  T   +  
Sbjct: 384  PFECNECGKAFSHKSALTLH---QRTHT-------------GEKPYQCNACGKTFYQKSD 427

Query: 1439 LDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYH 1498
            L  H + H G + Y+C +C  S      +T H R HTGEKP+ C  C  +    S L  H
Sbjct: 428  LTKHQRTHTGQKPYECYECGKSFCMNSHLTVHQRTHTGEKPFECLECGKSFCQKSHLTQH 487

Query: 1499 MRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETR 1558
             R H  ++ Y C  CG      + L  H   HTGLKPY+C EC         L +HQ T 
Sbjct: 488  QRTHIGDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECGKTFCLKSDLTIHQRT- 546

Query: 1559 HREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDR 1618
            H   + F C +CGK F  +  L  H R H+  KPY C+ C + F   + L  H  THT  
Sbjct: 547  HTGEKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGE 606

Query: 1619 HPFFCRLCNYKAKQKFQVVKHVRRH 1643
             P+ C  C     QK Q+ +H R H
Sbjct: 607  KPYECNECGKTFCQKSQLTQHQRIH 631



 Score =  154 bits (388), Expect = 9e-37
 Identities = 124/445 (27%), Positives = 177/445 (39%), Gaps = 62/445 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            F C  C  +   + AL  HQ        +GE    C+ C  T    + L  HQ+      
Sbjct: 385  FECNECGKAFSHKSALTLHQ-----RTHTGEKPYQCNACGKTFYQKSDLTKHQRTH---- 435

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQH---RRLKHEGVKPHQCPFCDFSTTRRYRLEAH 1218
                G +P+ +C +CG    +S CM  H    +  H G KP +C  C  S  ++  L  H
Sbjct: 436  ---TGQKPY-ECYECG----KSFCMNSHLTVHQRTHTGEKPFECLECGKSFCQKSHLTQH 487

Query: 1219 QSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNS 1278
            Q  H G     C++C +TF   S L  H++ +H     + C  C  +  L+ D+T H  +
Sbjct: 488  QRTHIGDKPYECNACGKTFYHKSVLTRHQI-IHTGLKPYECYECGKTFCLKSDLTIHQRT 546

Query: 1279 CHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCP 1338
             H G   FAC +C   FS ++ L QH  R H             T E P  C  CG +  
Sbjct: 547  -HTGEKPFACPECGKFFSHKSTLSQH-YRTH-------------TGEKPYECHECGKIFY 591

Query: 1339 SPASLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVG 1394
            + + L  H R        EC  C + F  +  L +H+R       + C  C  A   +  
Sbjct: 592  NKSYLTKHNRTHTGEKPYECNECGKTFCQKSQLTQHQRIHIGEKPYECNECGKAFCHKSA 651

Query: 1395 LVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFC--DFTCRHQLVLDHHVKGHGGTRLY 1452
            L+ H     +E                 P  C  C   F  +  L+L  H + H G + Y
Sbjct: 652  LIVHQRTHTQEK----------------PYKCNECGKSFCVKSGLIL--HERKHTGEKPY 693

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
            +C +C  S  ++  +T H R HTGEK   C+ C       S L  H R H  E+ Y C  
Sbjct: 694  ECNECGKSFSHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSDLAKHQRSHTGEKPYECNT 753

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQ 1537
            C       + L  H   H G KPY+
Sbjct: 754  CRKTFSQKSNLIVHQRTHIGEKPYE 778



 Score =  151 bits (382), Expect = 5e-36
 Identities = 98/353 (27%), Positives = 145/353 (41%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F   +HL  H   H  +   +C  C K F  KS L  H    +G+K + 
Sbjct: 439 KPYECYECGKSFCMNSHLTVHQRTHTGEKPFECLECGKSFCQKSHLTQHQRTHIGDKPYE 498

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH   +H  +       Y C  C + F L   L  H ++HT    
Sbjct: 499 CNACGKTFYHKSVLTRHQI-IHTGLK-----PYECYECGKTFCLKSDLTIHQRTHTGEK- 551

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C +  C      +    +H +   G +  EC  H C  +F     +  H+++H
Sbjct: 552 ----PFACPE--CGKFFSHKSTLSQHYRTHTGEKPYEC--HECGKIFYNKSYLTKHNRTH 603

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C      K    +H++  H G +   C  C  A  +  A   H  + H  
Sbjct: 604 TGEKPYECNECGKTFCQKSQLTQHQRI-HIGEKPYECNECGKAFCHKSALIVHQ-RTHTQ 661

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC  +   K  LI H   HTGEKP++C  C  +    S L+ H   H+  K  
Sbjct: 662 EKPYKCNECGKSFCVKSGLILHERKHTGEKPYECNECGKSFSHKSSLTVHHRAHTGEKSC 721

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C ECG +   K  L  H R H G+  Y+CN C     +   L  H+  H G+
Sbjct: 722 QCNECGKIFYRKSDLAKHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRTHIGE 774



 Score =  150 bits (378), Expect = 1e-35
 Identities = 124/465 (26%), Positives = 187/465 (40%), Gaps = 54/465 (11%)

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTH----------------L 210
           E  R F   + L+ H      D   +  +C+KF   KS L  H                 
Sbjct: 251 EFGRTFCDSSSLLFHQIPPSKDSHYEFSDCEKFLCVKSTLSKHDGVPVKHYDCGESGNNF 310

Query: 211 LREL----------GEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCRE 260
            R+L          GEK   C  C  +  E++ L RH   +H    +F      C  C +
Sbjct: 311 RRKLCLSQLQKGDKGEKHFECNECGKAFWEKSHLTRHQ-RVHTGEKHF-----QCNQCGK 364

Query: 261 EFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRH 320
            F     L +H +SHT        P  C +  C  A   + A   H +   G +  +C  
Sbjct: 365 TFWEKSNLTKHQRSHTGEK-----PFECNE--CGKAFSHKSALTLHQRTHTGEKPYQC-- 415

Query: 321 HSCPMLFATAEAMEAHHKSHYA---FHCPHCDFA-CSNKHLFRKHKKQGHPGSEELRCTF 376
           ++C   F     +  H ++H     + C  C  + C N HL   H++  H G +   C  
Sbjct: 416 NACGKTFYQKSDLTKHQRTHTGQKPYECYECGKSFCMNSHL-TVHQRT-HTGEKPFECLE 473

Query: 377 CPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDF 436
           C   +F   ++     + H  +K ++C  C     HK VL RH ++HTG KP++C  C  
Sbjct: 474 CG-KSFCQKSHLTQHQRTHIGDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECGK 532

Query: 437 TCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHR 496
           T    S L+ H  TH+  K + C ECG     K  L  H R H G+  Y+C++C    + 
Sbjct: 533 TFCLKSDLTIHQRTHTGEKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYN 592

Query: 497 ADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRH 555
              L+ H   H G K   C  C     +K +L +H   + H G     Y C+ C     H
Sbjct: 593 KSYLTKHNRTHTGEKPYECNECGKTFCQKSQLTQH--QRIHIGEKP--YECNECGKAFCH 648

Query: 556 KQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
           K A++ H+   HT+ + + C  C       + L+ H+RK  G  P
Sbjct: 649 KSALIVHQR-THTQEKPYKCNECGKSFCVKSGLILHERKHTGEKP 692



 Score =  132 bits (331), Expect = 4e-30
 Identities = 84/297 (28%), Positives = 122/297 (41%), Gaps = 13/297 (4%)

Query: 1355 ECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAAR--ERVGLVKHYL----EQHEETSA 1408
            E   CQE    +   +  +R+    + C   +F     +   L+ H +    + H E S 
Sbjct: 220  EYSICQETLLEKAVFNTRKRENAEENNCDYNEFGRTFCDSSSLLFHQIPPSKDSHYEFSD 279

Query: 1409 A----VAASDGDGDAGQPPLH--CPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTK 1462
                    S      G P  H  C       R +L L    KG  G + ++C +C  +  
Sbjct: 280  CEKFLCVKSTLSKHDGVPVKHYDCGESGNNFRRKLCLSQLQKGDKGEKHFECNECGKAFW 339

Query: 1463 NRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQ 1522
             +  +T H R+HTGEK + C+ C     + S L  H R H  E+ + C ECG      + 
Sbjct: 340  EKSHLTRHQRVHTGEKHFQCNQCGKTFWEKSNLTKHQRSHTGEKPFECNECGKAFSHKSA 399

Query: 1523 LKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRT 1582
            L  H   HTG KPYQC  C     +   L  HQ T H   + + C +CGK+F     L  
Sbjct: 400  LTLHQRTHTGEKPYQCNACGKTFYQKSDLTKHQRT-HTGQKPYECYECGKSFCMNSHLTV 458

Query: 1583 HLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKH 1639
            H R H+  KP+ C  C ++F   + L  H  TH    P+ C  C      K  + +H
Sbjct: 459  HQRTHTGEKPFECLECGKSFCQKSHLTQHQRTHIGDKPYECNACGKTFYHKSVLTRH 515



 Score =  128 bits (322), Expect = 4e-29
 Identities = 94/379 (24%), Positives = 153/379 (40%), Gaps = 25/379 (6%)

Query: 114 GQETAEEENVEKEEKSDTQKDSQKAVDKGQG-AQRLEGDVVSGTESLFKTHMCPECKRCF 172
           G+   ++ ++ K +++ T +   +  + G+         V   T +  K   C EC + F
Sbjct: 419 GKTFYQKSDLTKHQRTHTGQKPYECYECGKSFCMNSHLTVHQRTHTGEKPFECLECGKSF 478

Query: 173 KKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN 232
            +++HL +H   H  D   +C  C K F  KS L  H +   G K + C  C  +   ++
Sbjct: 479 CQKSHLTQHQRTHIGDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECGKTFCLKS 538

Query: 233 ALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEG 292
            L  H  +   +        +ACP C + F     L +H ++HT        P  C +  
Sbjct: 539 DLTIHQRTHTGE------KPFACPECGKFFSHKSTLSQHYRTHTGEK-----PYECHE-- 585

Query: 293 CSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCD 349
           C     ++    KH +   G +  EC  + C   F     +  H + H     + C  C 
Sbjct: 586 CGKIFYNKSYLTKHNRTHTGEKPYEC--NECGKTFCQKSQLTQHQRIHIGEKPYECNECG 643

Query: 350 FACSNKHLFRKHKKQGHPGSEELRCTFC--PFATFNPVAYQDHVGKMHAHEKIHQCPECN 407
            A  +K     H++  H   +  +C  C   F   + +   +   + H  EK ++C EC 
Sbjct: 644 KAFCHKSALIVHQRT-HTQEKPYKCNECGKSFCVKSGLILHE---RKHTGEKPYECNECG 699

Query: 408 FATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTK 467
            + +HK  L  H   HTGEK  +C  C       S L+KH  +H+  K Y C  C     
Sbjct: 700 KSFSHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSDLAKHQRSHTGEKPYECNTCRKTFS 759

Query: 468 WKHYLRVHMRKHAGDLRYQ 486
            K  L VH R H G+  Y+
Sbjct: 760 QKSNLIVHQRTHIGEKPYE 778



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 55/235 (23%), Positives = 79/235 (33%), Gaps = 55/235 (23%)

Query: 1463 NRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQ 1522
            +R+    H +I T +  +   +C     + +      R + EE      E G      + 
Sbjct: 202  HRENTLQHEKIQTLDHNFEYSICQETLLEKAVFNTRKRENAEENNCDYNEFGRTFCDSSS 261

Query: 1523 LKYH------------------------MTKHTGL------------------------- 1533
            L +H                        ++KH G+                         
Sbjct: 262  LLFHQIPPSKDSHYEFSDCEKFLCVKSTLSKHDGVPVKHYDCGESGNNFRRKLCLSQLQK 321

Query: 1534 -----KPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHS 1588
                 K ++C EC         L  HQ   H   + F C QCGK F  +  L  H R H+
Sbjct: 322  GDKGEKHFECNECGKAFWEKSHLTRHQRV-HTGEKHFQCNQCGKTFWEKSNLTKHQRSHT 380

Query: 1589 EAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
              KP+ CN C +AF   + L  H  THT   P+ C  C     QK  + KH R H
Sbjct: 381  GEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFYQKSDLTKHQRTH 435



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + F C  C      + AL LH RT      +P  C  CG +F Q+  L+ H
Sbjct: 383 KPFECNECGKAFSHKSALTLHQRT--HTGEKPYQCNACGKTFYQKSDLTKH 431



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + + C  C      + AL +H RT  Q   +P  C ECG SF  + GL  H
Sbjct: 635 KPYECNECGKAFCHKSALIVHQRTHTQ--EKPYKCNECGKSFCVKSGLILH 683



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + + C  C      +  L +H RT      +P  CPECG  F  +  LS H
Sbjct: 523 KPYECYECGKTFCLKSDLTIHQRT--HTGEKPFACPECGKFFSHKSTLSQH 571


>gi|153792259 zinc finger protein 778 [Homo sapiens]
          Length = 729

 Score =  223 bits (568), Expect = 1e-57
 Identities = 148/495 (29%), Positives = 216/495 (43%), Gaps = 48/495 (9%)

Query: 1133 GELHCSL--CPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHR 1190
            GE  C L  C   +P +++L  H  R H    P        +C +CG        + +H 
Sbjct: 277  GEKPCELEECGKASPVSSSLTQHV-RIHAAEKPC-------ECKECGKAFTGLSGLSKHV 328

Query: 1191 RLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRV 1250
            +    G KP++C  C  +    Y L  H   HT      C  C + F  +S L  H +R+
Sbjct: 329  QTD-PGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNH-VRI 386

Query: 1251 HDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHP 1310
            H     + C  C  +  +R  +TRHV + H G   + C  C   F + + L +H +R H 
Sbjct: 387  HTGIKPYTCSYCGKAFTVRCGLTRHVRT-HTGEKPYTCKDCGKAFCTSSGLTEH-VRTH- 443

Query: 1311 EPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEAFPSRLA 1368
                        T E P  C  CG      +SL  H R        EC  C +AF  R  
Sbjct: 444  ------------TGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSG 491

Query: 1369 LDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHC 1426
            L +H R       + C+ C   A  RV L+  +++ H E               + P  C
Sbjct: 492  LTKHMRTHTGEKPYECKDCG-KAYNRVYLLNEHVKTHTE---------------EKPFIC 535

Query: 1427 PFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCP 1486
              C  + R+   L+ H++ H G + Y+C DC  +      +T H R HTGEKPY C +C 
Sbjct: 536  TVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCG 595

Query: 1487 YACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTN 1546
             A    S L  H+R H  E+ Y+C ECG      + L  H   HTG KPY C EC     
Sbjct: 596  KAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFR 655

Query: 1547 RADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAA 1606
             +  L  H    H   + + C++CGKA+   +LL+ HL+ ++E + +VC  C ++F+ ++
Sbjct: 656  ASSHLHKHGRI-HTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGKSFKNSS 714

Query: 1607 GLRHHALTHTDRHPF 1621
             L HH   HTD  PF
Sbjct: 715  CLNHHTQIHTDEKPF 729



 Score =  183 bits (464), Expect = 1e-45
 Identities = 135/507 (26%), Positives = 200/507 (39%), Gaps = 68/507 (13%)

Query: 1175 DCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCP 1234
            +CG     S  + QH R+ H   KP +C  C  + T    L  H     G     C  C 
Sbjct: 285  ECGKASPVSSSLTQHVRI-HAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCG 343

Query: 1235 QTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHD--ITRHVNSCHQGTPAFACSQCE 1292
            +  G    L  H  + H +     C +C    Y R+   +  HV   H G   + CS C 
Sbjct: 344  KACGGFYLLNEHG-KTHTREKPFACVVC--GKYFRNSSCLNNHVR-IHTGIKPYTCSYCG 399

Query: 1293 AQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ-- 1350
              F+    L +H +R H             T E P  C  CG    + + L  H R    
Sbjct: 400  KAFTVRCGLTRH-VRTH-------------TGEKPYTCKDCGKAFCTSSGLTEHVRTHTG 445

Query: 1351 HPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAV 1410
                EC  C ++F    +L EH R                                    
Sbjct: 446  EKPYECKDCGKSFTVSSSLTEHARIH---------------------------------- 471

Query: 1411 AASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWH 1470
                     G+ P  C  C      +  L  H++ H G + Y+C DC  +      +  H
Sbjct: 472  --------TGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEH 523

Query: 1471 SRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKH 1530
             + HT EKP+ C +C  +  + S L  H++IH   + Y C +CG      + L  H+  H
Sbjct: 524  VKTHTEEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTH 583

Query: 1531 TGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEA 1590
            TG KPY+C  C      +  L VH  T H   + ++C++CGKAF +   L  H R H+  
Sbjct: 584  TGEKPYECKVCGKAFTTSSHLIVHIRT-HTGEKPYICKECGKAFASSSHLIEHRRTHTGE 642

Query: 1591 KPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVK-HVRRHHPDQAD 1649
            KPY+CN C +AFR ++ L  H   HT + P+ C+ C  KA  +F ++K H++ +  +Q  
Sbjct: 643  KPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECG-KAYNRFYLLKEHLKTYTEEQVF 701

Query: 1650 PNQGVGKDPTTPTVHLHDVQLEDPSPP 1676
              +  GK     +   H  Q+     P
Sbjct: 702  VCKDCGKSFKNSSCLNHHTQIHTDEKP 728



 Score =  169 bits (429), Expect = 2e-41
 Identities = 116/431 (26%), Positives = 165/431 (38%), Gaps = 65/431 (15%)

Query: 1215 LEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITR 1274
            +E H  R+  +    C  C + F   + L   R++VH          C  +  +   +T+
Sbjct: 244  VEMHAVRNPHV----CRECGKAFRYTAYLT-GRVQVHPGEKPCELEECGKASPVSSSLTQ 298

Query: 1275 HVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCG 1334
            HV   H       C +C   F+  + L +H         Q  PG      + P  C  CG
Sbjct: 299  HVR-IHAAEKPCECKECGKAFTGLSGLSKHV--------QTDPG------QKPYECKDCG 343

Query: 1335 LLCPSPASLRGH--TRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARER 1392
              C     L  H  T  +     C  C + F +   L+ H R                  
Sbjct: 344  KACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIH---------------- 387

Query: 1393 VGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLY 1452
                                       G  P  C +C      +  L  HV+ H G + Y
Sbjct: 388  --------------------------TGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKPY 421

Query: 1453 KCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPE 1512
             C DC  +      +T H R HTGEKPY C  C  +    S L  H RIH  E+ Y C +
Sbjct: 422  TCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQ 481

Query: 1513 CGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGK 1572
            CG      + L  HM  HTG KPY+C +C    NR   L  H +T H E + F+C  C K
Sbjct: 482  CGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKT-HTEEKPFICTVCRK 540

Query: 1573 AFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQ 1632
            +F+    L  H++ H+  KPY C  C + F  ++ L  H  THT   P+ C++C      
Sbjct: 541  SFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTT 600

Query: 1633 KFQVVKHVRRH 1643
               ++ H+R H
Sbjct: 601  SSHLIVHIRTH 611



 Score =  160 bits (406), Expect = 7e-39
 Identities = 118/456 (25%), Positives = 185/456 (40%), Gaps = 43/456 (9%)

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHY 226
           EC +     + L +H+ +H  +   +C  C K FT  S L  H+  + G+K + C  C  
Sbjct: 285 ECGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGK 344

Query: 227 SAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH------TAAAA 280
           +      LN H  +   +        +AC VC + FR S  L  H++ H      T +  
Sbjct: 345 ACGGFYLLNEHGKTHTRE------KPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYC 398

Query: 281 AEPLPLRC---------------FQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPM 325
            +   +RC                 + C  A        +H++   G +  EC+   C  
Sbjct: 399 GKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECK--DCGK 456

Query: 326 LFATAEAMEAH---HKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATF 382
            F  + ++  H   H     + C  C  A + +    KH +  H G +   C  C  A  
Sbjct: 457 SFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRT-HTGEKPYECKDCGKAYN 515

Query: 383 NPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVS 442
                 +HV K H  EK   C  C  +  +   L +H+ +HTG KP++C+ C  T    S
Sbjct: 516 RVYLLNEHV-KTHTEEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSS 574

Query: 443 YLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSS 502
            L++H+ TH+  K Y C  CG       +L VH+R H G+  Y C +C      +  L  
Sbjct: 575 SLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIE 634

Query: 503 HKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLS 561
           H+  H G K  +C  C  A +    L KH   + H G     Y C  C     + +  L 
Sbjct: 635 HRRTHTGEKPYICNECGKAFRASSHLHKH--GRIHTGQKP--YKCKECG--KAYNRFYLL 688

Query: 562 HENCK-HTRLREFHCALCDYRTFSNTTLLFHKRKAH 596
            E+ K +T  + F C  C  ++F N++ L H  + H
Sbjct: 689 KEHLKTYTEEQVFVCKDCG-KSFKNSSCLNHHTQIH 723



 Score =  160 bits (406), Expect = 7e-39
 Identities = 111/417 (26%), Positives = 172/417 (41%), Gaps = 26/417 (6%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C +       L EH   H  +    C  C K+F + S L  H+    G K + 
Sbjct: 335 KPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYT 394

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R  L RH+ +   +        Y C  C + F  S  L EH+++HT    
Sbjct: 395 CSYCGKAFTVRCGLTRHVRTHTGE------KPYTCKDCGKAFCTSSGLTEHVRTHTGEK- 447

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P  C   G S+      +  +H +   G +  EC+   C   F     +  H ++H
Sbjct: 448 ----PYECKDCGKSFTVSS--SLTEHARIHTGEKPYECKQ--CGKAFTGRSGLTKHMRTH 499

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A +  +L  +H K  H   +   CT C  +  N      H+ ++H  
Sbjct: 500 TGEKPYECKDCGKAYNRVYLLNEHVKT-HTEEKPFICTVCRKSFRNSSCLNKHI-QIHTG 557

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
            K ++C +C         L  H+  HTGEKP++C++C       S+L  H+ TH+  K Y
Sbjct: 558 IKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPY 617

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
           +C ECG       +L  H R H G+  Y CN+C      +  L  H   H G K   C+ 
Sbjct: 618 ICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKE 677

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
           C  A  R Y L++H+ +     T   ++ C  C  +S    + L+H    HT  + F
Sbjct: 678 CGKAYNRFYLLKEHLKTY----TEEQVFVCKDCG-KSFKNSSCLNHHTQIHTDEKPF 729



 Score =  126 bits (317), Expect = 2e-28
 Identities = 109/465 (23%), Positives = 173/465 (37%), Gaps = 53/465 (11%)

Query: 167 ECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHY 226
           +C + F    ++V        D SL   +C + F ++S L+       GE+      C  
Sbjct: 174 QCGKAFSSTPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCG- 231

Query: 227 SAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPL 286
                 AL   M        +   + + C  C + FR +  L   ++ H       P   
Sbjct: 232 -----KALTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVH-------PGEK 279

Query: 287 RCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKS---HYAF 343
            C  E C  A+P   +  +H++     +  EC+   C   F     +  H ++      +
Sbjct: 280 PCELEECGKASPVSSSLTQHVRIHAAEKPCECKE--CGKAFTGLSGLSKHVQTDPGQKPY 337

Query: 344 HCPHCDFACSNKHLFRKHKKQG---------------------------HPGSEELRCTF 376
            C  C  AC   +L  +H K                             H G +   C++
Sbjct: 338 ECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSY 397

Query: 377 CPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDF 436
           C  A         HV + H  EK + C +C  A      L  H+  HTGEKP++C+ C  
Sbjct: 398 CGKAFTVRCGLTRHV-RTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGK 456

Query: 437 TCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHR 496
           +    S L++H   H+  K Y C +CG     +  L  HMR H G+  Y+C  C    +R
Sbjct: 457 SFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNR 516

Query: 497 ADQLSSHKLRH-QGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRH 555
              L+ H   H + K  +C VC  + +    L KH+  Q H G     Y C  C      
Sbjct: 517 VYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHI--QIHTGIKP--YECKDCGKTFTV 572

Query: 556 KQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
             ++  H    HT  + + C +C     +++ L+ H R   G  P
Sbjct: 573 SSSLTEHIRT-HTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKP 616



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 80/341 (23%), Positives = 114/341 (33%), Gaps = 43/341 (12%)

Query: 1359 CQEAFPSRLALDEHRRQQH-------------FSHRCQLCDFAARERVGLVKHYLEQHEE 1405
            C EAF     L  H R Q+             F   CQ   F   E+  ++    +    
Sbjct: 122  CGEAFSEHSGLSTHVRTQNTGDSCVSNHYERDFFIPCQKTLFKIGEQFSVLGQCGKAFSS 181

Query: 1406 TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQ 1465
            T   V+      D     L    C     +Q  L      H G   +K   C  +  +  
Sbjct: 182  TPNVVSQQACTRDRS---LDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSM 238

Query: 1466 KITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKY 1525
                   +H    P+ C  C  A    + L   +++H  E+     ECG      + L  
Sbjct: 239  GCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVSSSLTQ 298

Query: 1526 HMTKHTGLKPYQCPECEYCTNRADALRVHQET---------------------------R 1558
            H+  H   KP +C EC         L  H +T                            
Sbjct: 299  HVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKACGGFYLLNEHGKT 358

Query: 1559 HREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDR 1618
            H   + F C  CGK F+    L  H+R H+  KPY C+ C +AF    GL  H  THT  
Sbjct: 359  HTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGE 418

Query: 1619 HPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPT 1659
             P+ C+ C         + +HVR H  ++    +  GK  T
Sbjct: 419  KPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFT 459


>gi|209954795 zinc finger protein 761 [Homo sapiens]
          Length = 746

 Score =  222 bits (566), Expect = 2e-57
 Identities = 188/682 (27%), Positives = 269/682 (39%), Gaps = 95/682 (13%)

Query: 1008 GNSSPTEALKK-----HRFEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTP 1062
            G+ +P   +KK      R++Q   H  + P      SS  SH+ E               
Sbjct: 108  GHEAPMTKIKKLTGITERYDQS--HARNKPIKDQLGSSFHSHLPEMHIFQTEEKIDNQVV 165

Query: 1063 QTQPDVSPLSNGD--SAPPKNGSTESSSGD--GDTVLVQKQ----KGARFSCPTCPFSCQ 1114
            ++  D S +S     S  PK   + +   +    ++L QKQ    +   F C     +  
Sbjct: 166  KSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCNESGKAFN 225

Query: 1115 QERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCG 1174
                LR HQI    +  + +  C +C         L  H +R H       G  P+ +C 
Sbjct: 226  YSSLLRKHQI----IHLADKYKCDVCGKLFNQKRNLACH-RRCHT------GENPY-KCN 273

Query: 1175 DCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCP 1234
            +CG T  Q+  +  HRRL H G KP++C  CD +   +  LE H+  HT      C+ C 
Sbjct: 274  ECGKTFSQTSSLTCHRRL-HTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECG 332

Query: 1235 QTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQ 1294
            +TF   S L  H  R+H     + C  C  +   +  +T H +  H G   + C++C   
Sbjct: 333  KTFRQKSILTRHH-RLHTGEKPYKCNECGKTFSHKSSLTCH-HRLHTGEKPYKCNECGKT 390

Query: 1295 FSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPR- 1353
            FS +++L  H  R H             T E P  C  C       ++   H RK H   
Sbjct: 391  FSHKSSLTCHR-RLH-------------TGEKPYKCEECDKAYSFRSNFEIH-RKIHTED 435

Query: 1354 --LECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAA 1409
               +C  C + F    +L  HRR+      ++C+ CD A R      K  LE+H      
Sbjct: 436  NAYKCNECGKTFSRTSSLTCHRRRHTGEQPYKCEECDKAFR-----FKSNLERHRRIHT- 489

Query: 1410 VAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITW 1469
                      G+ P  C  C  T   +  L  H + H G + YKC +C  +   +  +T 
Sbjct: 490  ----------GEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTC 539

Query: 1470 HSRIHTGEKPYHCHLC---------------------PYACADP-------SRLKYHMRI 1501
            H R+H+GEKPY C  C                     PY C D        S L+ H +I
Sbjct: 540  HRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKI 599

Query: 1502 HKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHRE 1561
            H EE  Y C ECG      + L  H   HTG KPY+C EC+        L  H+   H  
Sbjct: 600  HTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRI-HTG 658

Query: 1562 ARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPF 1621
             + + C +CGK F  +     H R H+  KPY CN C + F   + L  H   HT   P+
Sbjct: 659  EKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPY 718

Query: 1622 FCRLCNYKAKQKFQVVKHVRRH 1643
             C  C     QK  +  H R H
Sbjct: 719  KCNECGKTFSQKSNLTCHRRLH 740



 Score =  187 bits (474), Expect = 1e-46
 Identities = 144/531 (27%), Positives = 210/531 (39%), Gaps = 69/531 (12%)

Query: 1103 RFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAA 1162
            ++ C  C     Q+R L  H  R C   E+    C+ C  T    ++L  H +R H    
Sbjct: 241  KYKCDVCGKLFNQKRNLACH--RRCHTGEN-PYKCNECGKTFSQTSSLTCH-RRLHTGEK 296

Query: 1163 PAR----------------------GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPH 1200
            P +                        +P+ +C +CG T +Q   + +H RL H G KP+
Sbjct: 297  PYKCEECDKAFHFKSILERHRIIHTEEKPY-KCNECGKTFRQKSILTRHHRL-HTGEKPY 354

Query: 1201 QCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCP 1260
            +C  C  + + +  L  H   HTG     C+ C +TF   S L  HR R+H     + C 
Sbjct: 355  KCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHR-RLHTGEKPYKCE 413

Query: 1261 LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSP 1320
             CD +   R +   H    H    A+ C++C   FS  ++L  H  RR     QP     
Sbjct: 414  ECDKAYSFRSNFEIH-RKIHTEDNAYKCNECGKTFSRTSSLTCH--RRRHTGEQPYKCEE 470

Query: 1321 AE----------------TTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEA 1362
             +                T E P  C+ CG      + L  H R        +C  C + 
Sbjct: 471  CDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKT 530

Query: 1363 FPSRLALDEHRRQQHFS--HRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAG 1420
            F  + +L  HRR       ++C+ C     +++ L +H                    +G
Sbjct: 531  FSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLH----------------SG 574

Query: 1421 QPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPY 1480
            + P  C   D     +  L+ H K H     YKC +C  +      +T H R+HTGEKPY
Sbjct: 575  ENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPY 634

Query: 1481 HCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPE 1540
             C  C  A    S L+ H RIH  E+ Y C ECG      +    H   HTG KPY+C E
Sbjct: 635  KCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNE 694

Query: 1541 CEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAK 1591
            C    ++  +L  H    H   + + C +CGK F  +  L  H R H+  K
Sbjct: 695  CGKNFSQKSSLICHHRL-HTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEK 744



 Score =  172 bits (437), Expect = 2e-42
 Identities = 127/488 (26%), Positives = 204/488 (41%), Gaps = 36/488 (7%)

Query: 119 EEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHL 178
           +++ V   EKS    +S KA +     ++ +         L   + C  C + F ++ +L
Sbjct: 204 QKQEVHMREKSFQCNESGKAFNYSSLLRKHQ------IIHLADKYKCDVCGKLFNQKRNL 257

Query: 179 VEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHM 238
             H   H  +   +C  C K F+  S L  H     GEK + C  C  +   ++ L RH 
Sbjct: 258 ACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHR 317

Query: 239 ASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAP 298
               E+        Y C  C + FR    L  H + HT        P +C + G +++  
Sbjct: 318 IIHTEE------KPYKCNECGKTFRQKSILTRHHRLHTGEK-----PYKCNECGKTFS-- 364

Query: 299 DRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNK 355
            + +   H +   G +  +C  + C   F+   ++  H + H     + C  CD A S +
Sbjct: 365 HKSSLTCHHRLHTGEKPYKC--NECGKTFSHKSSLTCHRRLHTGEKPYKCEECDKAYSFR 422

Query: 356 HLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRV 415
             F  H+K  H      +C  C   TF+  +      + H  E+ ++C EC+ A   K  
Sbjct: 423 SNFEIHRKI-HTEDNAYKCNECG-KTFSRTSSLTCHRRRHTGEQPYKCEECDKAFRFKSN 480

Query: 416 LIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVH 475
           L RH  +HTGEKP+KC  C  T    SYL+ H   H+  K Y C ECG    WK  L  H
Sbjct: 481 LERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCH 540

Query: 476 MRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKS-LMCEVC--AFACKRKYELQKHMA 532
            R H+G+  Y+C +C    ++   L  H+  H G++   CE    A++ K   E+ + + 
Sbjct: 541 RRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIH 600

Query: 533 SQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHK 592
           ++ +P      Y C+ C        ++  H    HT  + + C  CD      + L  H+
Sbjct: 601 TEENP------YKCNECGKTFSRTSSLTCHRRL-HTGEKPYKCEECDKAFRVKSNLEGHR 653

Query: 593 RKAHGYVP 600
           R   G  P
Sbjct: 654 RIHTGEKP 661



 Score =  163 bits (413), Expect = 1e-39
 Identities = 91/306 (29%), Positives = 133/306 (43%), Gaps = 19/306 (6%)

Query: 1353 RLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAAV 1410
            + +C  C + F  +  L  HRR       ++C  C     +   L  H            
Sbjct: 241  KYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLH-------- 292

Query: 1411 AASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWH 1470
                     G+ P  C  CD     + +L+ H   H   + YKC +C  + + +  +T H
Sbjct: 293  --------TGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRH 344

Query: 1471 SRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKH 1530
             R+HTGEKPY C+ C    +  S L  H R+H  E+ Y C ECG      + L  H   H
Sbjct: 345  HRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLH 404

Query: 1531 TGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEA 1590
            TG KPY+C EC+   +      +H++  H E  A+ C +CGK F     L  H R+H+  
Sbjct: 405  TGEKPYKCEECDKAYSFRSNFEIHRKI-HTEDNAYKCNECGKTFSRTSSLTCHRRRHTGE 463

Query: 1591 KPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADP 1650
            +PY C  C +AFR+ + L  H   HT   P+ C  C     +K  +  H R H  ++A  
Sbjct: 464  QPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYK 523

Query: 1651 NQGVGK 1656
                GK
Sbjct: 524  CNECGK 529



 Score =  162 bits (411), Expect = 2e-39
 Identities = 105/382 (27%), Positives = 161/382 (42%), Gaps = 38/382 (9%)

Query: 1280 HQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPS 1339
            H    +F C++    F+  + L++H +    +  +               C  CG L   
Sbjct: 209  HMREKSFQCNESGKAFNYSSLLRKHQIIHLADKYK---------------CDVCGKLFNQ 253

Query: 1340 PASLRGHTR---KQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVG 1394
              +L  H R    ++P  +C  C + F    +L  HRR       ++C+ CD A   +  
Sbjct: 254  KRNLACHRRCHTGENP-YKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSI 312

Query: 1395 LVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKC 1454
            L +H +   EE                 P  C  C  T R + +L  H + H G + YKC
Sbjct: 313  LERHRIIHTEEK----------------PYKCNECGKTFRQKSILTRHHRLHTGEKPYKC 356

Query: 1455 TDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECG 1514
             +C  +  ++  +T H R+HTGEKPY C+ C    +  S L  H R+H  E+ Y C EC 
Sbjct: 357  NECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECD 416

Query: 1515 YKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAF 1574
                + +  + H   HT    Y+C EC    +R  +L  H+  RH   + + CE+C KAF
Sbjct: 417  KAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRR-RHTGEQPYKCEECDKAF 475

Query: 1575 KTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKF 1634
            + +  L  H R H+  KPY CN C + F   + L  H   HT    + C  C      K 
Sbjct: 476  RFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKS 535

Query: 1635 QVVKHVRRHHPDQADPNQGVGK 1656
             +  H R H  ++    +  GK
Sbjct: 536  SLTCHRRLHSGEKPYKCKECGK 557



 Score =  155 bits (391), Expect = 4e-37
 Identities = 113/402 (28%), Positives = 156/402 (38%), Gaps = 49/402 (12%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F  ++ L  H  LH  +   +C  C K F+ KS L  H     GEK + 
Sbjct: 352 KPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYK 411

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   R+    H     ED      + Y C  C + F  + +L  H + HT    
Sbjct: 412 CEECDKAYSFRSNFEIHRKIHTED------NAYKCNECGKTFSRTSSLTCHRRRHTGEQ- 464

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C  E C  A   +    +H +   G +  +C  + C   F+    +  HH+ H
Sbjct: 465 ----PYKC--EECDKAFRFKSNLERHRRIHTGEKPYKC--NECGKTFSRKSYLTCHHRLH 516

Query: 341 Y---AFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHA- 396
               A+ C  C    S K     H++  H G +  +C  C   TFN         ++H+ 
Sbjct: 517 TGEKAYKCNECGKTFSWKSSLTCHRRL-HSGEKPYKCKECG-KTFNQQLTLKRHRRLHSG 574

Query: 397 ---------------------HEKIH------QCPECNFATAHKRVLIRHMLLHTGEKPH 429
                                H+KIH      +C EC    +    L  H  LHTGEKP+
Sbjct: 575 ENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPY 634

Query: 430 KCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQ 489
           KCE CD   R  S L  H   H+  K Y C ECG     K Y   H R H G+  Y+CN+
Sbjct: 635 KCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNE 694

Query: 490 CSYRCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKH 530
           C     +   L  H   H G K   C  C     +K  L  H
Sbjct: 695 CGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCH 736



 Score =  150 bits (379), Expect = 1e-35
 Identities = 118/464 (25%), Positives = 181/464 (39%), Gaps = 48/464 (10%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           KTH+       F   + L +   +H  + S QC    K F   S L+ H +  L +K + 
Sbjct: 185 KTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLADK-YK 243

Query: 221 CPLCHYSAVERNALNRHMAS-------MHEDISNFYSDT---------------YACPVC 258
           C +C     ++  L  H             +    +S T               Y C  C
Sbjct: 244 CDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEEC 303

Query: 259 REEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC 318
            + F     L+ H   HT     E  P +C +  C      +    +H +   G +  +C
Sbjct: 304 DKAFHFKSILERHRIIHT-----EEKPYKCNE--CGKTFRQKSILTRHHRLHTGEKPYKC 356

Query: 319 RHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCT 375
             + C   F+   ++  HH+ H     + C  C    S+K     H++  H G +  +C 
Sbjct: 357 --NECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRL-HTGEKPYKCE 413

Query: 376 FCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCD 435
            C  A      ++ H  K+H  +  ++C EC    +    L  H   HTGE+P+KCE CD
Sbjct: 414 ECDKAYSFRSNFEIH-RKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYKCEECD 472

Query: 436 FTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCH 495
              R  S L +H   H+  K Y C ECG     K YL  H R H G+  Y+CN+C     
Sbjct: 473 KAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFS 532

Query: 496 RADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKH--MASQHHPGTPAPLYPCHYCSYQ 552
               L+ H+  H G K   C+ C     ++  L++H  + S  +P      Y C      
Sbjct: 533 WKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENP------YKCEDSDKA 586

Query: 553 SRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAH 596
              K  +  H+   HT    + C  C  +TFS T+ L   R+ H
Sbjct: 587 YSFKSNLEIHQKI-HTEENPYKCNECG-KTFSRTSSLTCHRRLH 628



 Score =  140 bits (354), Expect = 8e-33
 Identities = 98/353 (27%), Positives = 149/353 (42%), Gaps = 20/353 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + +  R++   H  +H  D + +C  C K F+  S L  H  R  GE+ + 
Sbjct: 408 KPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYK 467

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L RH   +H          Y C  C + F     L  H + HT   A
Sbjct: 468 CEECDKAFRFKSNLERHRR-IHTG-----EKPYKCNECGKTFSRKSYLTCHHRLHTGEKA 521

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
                 +C + G +++   + +   H +   G +  +C+   C   F     ++ H + H
Sbjct: 522 -----YKCNECGKTFSW--KSSLTCHRRLHSGEKPYKCKE--CGKTFNQQLTLKRHRRLH 572

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C   D A S K     H+K  H      +C  C   TF+  +      ++H  
Sbjct: 573 SGENPYKCEDSDKAYSFKSNLEIHQKI-HTEENPYKCNECG-KTFSRTSSLTCHRRLHTG 630

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK ++C EC+ A   K  L  H  +HTGEKP+KC  C  T    SY   H   H+  K Y
Sbjct: 631 EKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPY 690

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGK 510
            C ECG     K  L  H R H G+  Y+CN+C     +   L+ H+  H G+
Sbjct: 691 KCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGE 743



 Score =  137 bits (346), Expect = 7e-32
 Identities = 114/452 (25%), Positives = 170/452 (37%), Gaps = 80/452 (17%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  + +Q+  L  H         +GE    C+ C  T    ++L  H +      
Sbjct: 326  YKCNECGKTFRQKSILTRHHRL-----HTGEKPYKCNECGKTFSHKSSLTCHHRLH---- 376

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C +CG T      +  HRRL H G KP++C  CD + + R   E H+  
Sbjct: 377  ---TGEKPY-KCNECGKTFSHKSSLTCHRRL-HTGEKPYKCEECDKAYSFRSNFEIHRKI 431

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HT      C+ C +TF   S L  HR R H     + C  CD +   + ++ RH    H 
Sbjct: 432  HTEDNAYKCNECGKTFSRTSSLTCHRRR-HTGEQPYKCEECDKAFRFKSNLERH-RRIHT 489

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPA--------------ETTEGP 1327
            G   + C++C   FS ++ L  H      E A                       + E P
Sbjct: 490  GEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKP 549

Query: 1328 LHCSRCGLLCPSPASLRGHTRKQ-----------------------HPRL-------ECG 1357
              C  CG       +L+ H R                         H ++       +C 
Sbjct: 550  YKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCN 609

Query: 1358 ACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDG 1415
             C + F    +L  HRR       ++C+ CD A R     VK  LE H            
Sbjct: 610  ECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFR-----VKSNLEGHRRIHT------- 657

Query: 1416 DGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHT 1475
                G+ P  C  C  T   +     H + H G + YKC +C  +   +  +  H R+HT
Sbjct: 658  ----GEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHT 713

Query: 1476 GEKPYHCHLCPYACADPSRLKYHMRIHKEERK 1507
            GEKPY C+ C    +  S L  H R+H  E++
Sbjct: 714  GEKPYKCNECGKTFSQKSNLTCHRRLHTGEKQ 745



 Score =  114 bits (285), Expect = 8e-25
 Identities = 81/296 (27%), Positives = 124/296 (41%), Gaps = 20/296 (6%)

Query: 163 HMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCP 222
           + C EC + F+ +++L  H  +H  +   +C  C K F+ KS L  H     GEKA+ C 
Sbjct: 466 YKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCN 525

Query: 223 LCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAE 282
            C  +   +++L  H   +H          Y C  C + F     LK H + H+      
Sbjct: 526 ECGKTFSWKSSLTCHRR-LHSG-----EKPYKCKECGKTFNQQLTLKRHRRLHSGEN--- 576

Query: 283 PLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA 342
             P +C     +Y+         H K        +C  + C   F+   ++  H + H  
Sbjct: 577 --PYKCEDSDKAYSFKSNLEI--HQKIHTEENPYKC--NECGKTFSRTSSLTCHRRLHTG 630

Query: 343 ---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEK 399
              + C  CD A   K     H++  H G +  +C  C   TF+  +Y     ++H  EK
Sbjct: 631 EKPYKCEECDKAFRVKSNLEGHRRI-HTGEKPYKCNECG-KTFSRKSYFICHHRLHTGEK 688

Query: 400 IHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTK 455
            ++C EC    + K  LI H  LHTGEKP+KC  C  T    S L+ H   H+  K
Sbjct: 689 PYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEK 744



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 126/556 (22%), Positives = 195/556 (35%), Gaps = 76/556 (13%)

Query: 836  FRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRK 895
            ++C  C  +  +++ L  H R  C     P  C ECG +F Q   L+ H          K
Sbjct: 242  YKCDVCGKLFNQKRNLACHRR--CHTGENPYKCNECGKTFSQTSSLTCHRRLHTG---EK 296

Query: 896  NKGLPRPDSPIPLQPVLPGTQASEDTESGKPPPASQ-----EAELLLPKDAPLELPREPE 950
                   D     + +L   +     E  KP   ++       + +L +   L    +P 
Sbjct: 297  PYKCEECDKAFHFKSILERHRIIHTEE--KPYKCNECGKTFRQKSILTRHHRLHTGEKPY 354

Query: 951  ETEEPLATVSGSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVP----- 1005
            +  E   T S        + L T      C +      + S     ++ H    P     
Sbjct: 355  KCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEE 414

Query: 1006 ---PAGNSSPTEALKKHRFEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTP 1062
                    S  E  +K   E   + CN C    SR SS+T H             +R   
Sbjct: 415  CDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCH-------------RRRHT 461

Query: 1063 QTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTH 1122
              QP      +       N         G+           + C  C  +  ++  L  H
Sbjct: 462  GEQPYKCEECDKAFRFKSNLERHRRIHTGE---------KPYKCNECGKTFSRKSYLTCH 512

Query: 1123 QIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTC 1180
                     +GE    C+ C  T    ++L  H +R H       G +P+ +C +CG T 
Sbjct: 513  H-----RLHTGEKAYKCNECGKTFSWKSSLTCH-RRLH------SGEKPY-KCKECGKTF 559

Query: 1181 KQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTN 1240
             Q   +++HRRL H G  P++C   D + + +  LE HQ  HT      C+ C +TF   
Sbjct: 560  NQQLTLKRHRRL-HSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRT 618

Query: 1241 SKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETA 1300
            S L  HR R+H     + C  CD +  ++ ++  H    H G   + C++C   FS ++ 
Sbjct: 619  SSLTCHR-RLHTGEKPYKCEECDKAFRVKSNLEGH-RRIHTGEKPYKCNECGKTFSRKSY 676

Query: 1301 LKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGA 1358
               H  R H             T E P  C+ CG      +SL  H R        +C  
Sbjct: 677  FICHH-RLH-------------TGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNE 722

Query: 1359 CQEAFPSRLALDEHRR 1374
            C + F  +  L  HRR
Sbjct: 723  CGKTFSQKSNLTCHRR 738



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/57 (35%), Positives = 29/57 (50%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEK 217
           K + C EC + F +++ L+ H  LH  +   +C  C K F+ KS L  H     GEK
Sbjct: 688 KPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEK 744



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 6/59 (10%)

Query: 828 VIQGEGRAFRCPHCPFITRREKALNLHSR--TGCQGRREPLLCPECGASFKQQRGLSTH 884
           +I  E + ++C  C    R++  L  H R  TG     +P  C ECG +F  +  L+ H
Sbjct: 318 IIHTEEKPYKCNECGKTFRQKSILTRHHRLHTG----EKPYKCNECGKTFSHKSSLTCH 372



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           +A++C  C      + +L  H R       +P  C ECG +F QQ  L  H
Sbjct: 520 KAYKCNECGKTFSWKSSLTCHRRL--HSGEKPYKCKECGKTFNQQLTLKRH 568


>gi|172072608 zinc finger protein 624 [Homo sapiens]
          Length = 865

 Score =  222 bits (566), Expect = 2e-57
 Identities = 176/622 (28%), Positives = 249/622 (40%), Gaps = 60/622 (9%)

Query: 1057 GKRGTPQTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQ----KGARFSCPTCPFS 1112
            G +   QT        + +   P   ST   +    ++L+Q Q    K   + C  C  +
Sbjct: 253  GSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKT 312

Query: 1113 CQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPH 1170
              Q   L  H+        +GE    C+ C     A+++L +HQ R H    P       
Sbjct: 313  FSQPSYLSQHK-----KIHTGEKPYKCNECGKAFIASSSLMVHQ-RIHTKEKP------- 359

Query: 1171 LQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPC 1230
             QC  CG +  Q   + QH+R++  G KP++C  C  + + + +L  HQ  H G     C
Sbjct: 360  YQCNVCGKSFSQCARLNQHQRIQ-TGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKC 418

Query: 1231 SSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQ 1290
              C + F   S L +H+ + H +   + C  C  S +    I       H G   F C++
Sbjct: 419  DDCGKAFRNKSYLSVHQ-KTHTEEKPYQCNECGKS-FKNTTIFNVHQRIHTGEKPFRCNE 476

Query: 1291 CEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ 1350
            C   + S ++L  H +R H             T E P  C+ CG      A+   H R  
Sbjct: 477  CGKAYRSNSSLIVH-IRTH-------------TGEKPYECNECGKAFNRIANFTEHQRIH 522

Query: 1351 --HPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLVKHYLEQHEET 1406
                  +C  C +AF +   L  H R       ++C  C  A      L+ H     EE 
Sbjct: 523  TGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEK 582

Query: 1407 SAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQK 1466
                            P  C  C  + R +  L  H + H G + YKCTDC  +      
Sbjct: 583  ----------------PYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVN 626

Query: 1467 ITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYH 1526
            +  H +IHTG KPY C+ C  +    S L  H R H  E+ Y C EC       +QL  H
Sbjct: 627  LKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVH 686

Query: 1527 MTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRK 1586
              +HTG KPY+C EC            HQ T H   + F C  CGKAF     +  H + 
Sbjct: 687  QRRHTGEKPYKCNECGKVFTSNSGFNTHQRT-HTGEKPFKCNDCGKAFSQMVHVTEHQKI 745

Query: 1587 HSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPD 1646
            HS  KPY C+VC +AFR  + L  H  THT   P+ C+ C        Q+  H R H  +
Sbjct: 746  HSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGE 805

Query: 1647 QADPNQGVGKDPTTP---TVHL 1665
            +    +  GK   T    TVHL
Sbjct: 806  RPYKCEECGKAFRTNSDFTVHL 827



 Score =  207 bits (526), Expect = 9e-53
 Identities = 155/542 (28%), Positives = 219/542 (40%), Gaps = 73/542 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGE--LHCSLCPFTAPAATALRLHQKRRHPTA 1161
            + C  C  S  Q   L  HQ       ++GE    CS C       + L  HQ+  +   
Sbjct: 360  YQCNVCGKSFSQCARLNQHQ-----RIQTGEKPYKCSECGKAFSDKSKLARHQETHN--- 411

Query: 1162 APARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSR 1221
                G +P+ +C DCG   +    +  H++  H   KP+QC  C  S         HQ  
Sbjct: 412  ----GEKPY-KCDDCGKAFRNKSYLSVHQKT-HTEEKPYQCNECGKSFKNTTIFNVHQRI 465

Query: 1222 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQ 1281
            HTG     C+ C + + +NS L +H +R H     + C  C  +     + T H    H 
Sbjct: 466  HTGEKPFRCNECGKAYRSNSSLIVH-IRTHTGEKPYECNECGKAFNRIANFTEH-QRIHT 523

Query: 1282 GTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPA 1341
            G   + C++C   F + + L  H  R H             T E P  C+ CG      +
Sbjct: 524  GEKPYKCNECGKAFINYSCLTVHH-RMH-------------TGEKPYKCTECGKAFMRSS 569

Query: 1342 SLRGHTR---KQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGLV 1396
            SL  H R   ++ P L C  C E+F  +  L  H+R       ++C  C+ A  + V L 
Sbjct: 570  SLIIHQRIHTEEKPYL-CNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVNLK 628

Query: 1397 KH-----------------------YLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTC 1433
            +H                       YL  H+ T             G+ P  C  C+   
Sbjct: 629  EHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHT-----------GEKPYKCNECEKAF 677

Query: 1434 RHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPS 1493
             +   L  H + H G + YKC +C     +      H R HTGEKP+ C+ C  A +   
Sbjct: 678  TNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMV 737

Query: 1494 RLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRV 1553
             +  H +IH  E+ Y C  CG   +  + L  H   HTG KPY C EC         L +
Sbjct: 738  HVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTL 797

Query: 1554 HQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHAL 1613
            HQ   H   R + CE+CGKAF+T      HLR H+  KPY CN C +AFR ++ L  H  
Sbjct: 798  HQRI-HTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQR 856

Query: 1614 TH 1615
             H
Sbjct: 857  IH 858



 Score =  194 bits (492), Expect = 8e-49
 Identities = 132/456 (28%), Positives = 196/456 (42%), Gaps = 69/456 (15%)

Query: 1223 TGIGRIPCSSCP--QTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCH 1280
            T +G+I C      +     S+L L + + ++K   + C  C+ + + R  + +H  + H
Sbjct: 241  THLGKIICKEMKGSKAIRQTSELTLGK-KSNNKEKPYKCSTCEKAFHYRSLLIQHQRT-H 298

Query: 1281 QGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSP 1340
                 + C++C   FS  + L QH                  T E P  C+ CG    + 
Sbjct: 299  TKEKPYECNECGKTFSQPSYLSQH--------------KKIHTGEKPYKCNECGKAFIAS 344

Query: 1341 ASLRGHTR---KQHPRLECGACQEAFPSRLALDEHRRQQ--HFSHRCQLCDFAARERVGL 1395
            +SL  H R   K+ P  +C  C ++F     L++H+R Q     ++C  C  A  ++  L
Sbjct: 345  SSLMVHQRIHTKEKP-YQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKL 403

Query: 1396 VKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCT 1455
             +H  E H                G+ P  C  C    R++  L  H K H   + Y+C 
Sbjct: 404  ARHQ-ETHN---------------GEKPYKCDDCGKAFRNKSYLSVHQKTHTEEKPYQCN 447

Query: 1456 DCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECG- 1514
            +C  S KN      H RIHTGEKP+ C+ C  A    S L  H+R H  E+ Y C ECG 
Sbjct: 448  ECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGEKPYECNECGK 507

Query: 1515 --------------------YKCK-----WVNQ--LKYHMTKHTGLKPYQCPECEYCTNR 1547
                                YKC      ++N   L  H   HTG KPY+C EC     R
Sbjct: 508  AFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMR 567

Query: 1548 ADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAG 1607
            + +L +HQ   H E + ++C +CG++F+ +  L  H R H+  KPY C  C RAF     
Sbjct: 568  SSSLIIHQRI-HTEEKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVN 626

Query: 1608 LRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRH 1643
            L+ H   HT   P+ C  C    + K  ++ H R H
Sbjct: 627  LKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTH 662



 Score =  179 bits (455), Expect = 2e-44
 Identities = 140/530 (26%), Positives = 218/530 (41%), Gaps = 48/530 (9%)

Query: 96  KLPPGEREPSQEAG-------TPLPGQETAE--------EENVEKEEKSDTQKDSQKAVD 140
           ++ P ++ P+ + G        P PG  T E        EEN  +     T     K + 
Sbjct: 189 RIIPLKKTPTSQRGFRFESILIPEPGIATEELHSRCQTQEENFTENLNLITDTHLGKIIC 248

Query: 141 K---GQGAQRLEGDVVSGTES--LFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPN 195
           K   G  A R   ++  G +S    K + C  C++ F  R+ L++H   H  +   +C  
Sbjct: 249 KEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNE 308

Query: 196 CQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYAC 255
           C K F+  S L  H     GEK + C  C  + +  ++L  H     ++        Y C
Sbjct: 309 CGKTFSQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKE------KPYQC 362

Query: 256 PVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRA 315
            VC + F     L +H +  T        P +C +  C  A  D+    +H +  +G + 
Sbjct: 363 NVCGKSFSQCARLNQHQRIQTGEK-----PYKCSE--CGKAFSDKSKLARHQETHNGEKP 415

Query: 316 VECRHHSCPMLFATAEAMEAHHKSH---YAFHCPHCDFACSNKHLFRKHKKQGHPGSEEL 372
            +C    C   F     +  H K+H     + C  C  +  N  +F  H++  H G +  
Sbjct: 416 YKC--DDCGKAFRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRI-HTGEKPF 472

Query: 373 RCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCE 432
           RC  C  A  +  +   H+ + H  EK ++C EC  A         H  +HTGEKP+KC 
Sbjct: 473 RCNECGKAYRSNSSLIVHI-RTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCN 531

Query: 433 LCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSY 492
            C     + S L+ H   H+  K Y CTECG        L +H R H  +  Y CN+C  
Sbjct: 532 ECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGE 591

Query: 493 RCHRADQLSSHKLRHQG-KSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSY 551
                  L+ H+  H G K   C  C  A  +   L++H   + H G     Y C+ C  
Sbjct: 592 SFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVNLKEH--QKIHTGVKP--YKCYDCGK 647

Query: 552 QSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTT-LLFHKRKAHGYVP 600
             R K  ++ H+   HT  + + C  C+ + F+NT+ L  H+R+  G  P
Sbjct: 648 SFRTKSYLIVHQR-THTGEKPYKCNECE-KAFTNTSQLTVHQRRHTGEKP 695



 Score =  179 bits (454), Expect = 2e-44
 Identities = 130/486 (26%), Positives = 188/486 (38%), Gaps = 64/486 (13%)

Query: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAP 1163
            + C  C  + + +  L  HQ       E     C+ C  +    T   +HQ R H    P
Sbjct: 416  YKCDDCGKAFRNKSYLSVHQKTHT---EEKPYQCNECGKSFKNTTIFNVHQ-RIHTGEKP 471

Query: 1164 AR----------------------GPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQ 1201
             R                      G +P+ +C +CG    +     +H+R+ H G KP++
Sbjct: 472  FRCNECGKAYRSNSSLIVHIRTHTGEKPY-ECNECGKAFNRIANFTEHQRI-HTGEKPYK 529

Query: 1202 CPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPL 1261
            C  C  +      L  H   HTG     C+ C + F  +S L +H+ R+H +   + C  
Sbjct: 530  CNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQ-RIHTEEKPYLCNE 588

Query: 1262 CDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPA 1321
            C  S  ++  +T H    H G   + C+ CE  F+    LK+H                 
Sbjct: 589  CGESFRIKSHLTVH-QRIHTGEKPYKCTDCERAFTKMVNLKEH--------------QKI 633

Query: 1322 ETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRRQQ--H 1377
             T   P  C  CG    + + L  H R        +C  C++AF +   L  H+R+    
Sbjct: 634  HTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTGE 693

Query: 1378 FSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQL 1437
              ++C  C        G   H   Q   T             G+ P  C  C       +
Sbjct: 694  KPYKCNECGKVFTSNSGFNTH---QRTHT-------------GEKPFKCNDCGKAFSQMV 737

Query: 1438 VLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKY 1497
             +  H K H G + YKC  C  + +    +T H R HTGEKPY C  C   C   S+L  
Sbjct: 738  HVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTL 797

Query: 1498 HMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQET 1557
            H RIH  ER Y C ECG   +  +    H+  HTG KPY+C EC      + +L VHQ  
Sbjct: 798  HQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQRI 857

Query: 1558 RHREAR 1563
              RE +
Sbjct: 858  HQRETQ 863



 Score =  167 bits (423), Expect = 8e-41
 Identities = 118/444 (26%), Positives = 177/444 (39%), Gaps = 26/444 (5%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C  C + F +   L +H  +   +   +C  C K F+ KSKL  H     GEK + 
Sbjct: 358 KPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYK 417

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +   ++ L+ H  +  E+        Y C  C + F+ +     H + HT    
Sbjct: 418 CDDCGKAFRNKSYLSVHQKTHTEE------KPYQCNECGKSFKNTTIFNVHQRIHTGEK- 470

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P RC + G +Y +    + I H++   G +  EC  + C   F        H + H
Sbjct: 471 ----PFRCNECGKAYRS--NSSLIVHIRTHTGEKPYEC--NECGKAFNRIANFTEHQRIH 522

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C  A  N      H +  H G +  +CT C  A     +   H  ++H  
Sbjct: 523 TGEKPYKCNECGKAFINYSCLTVHHRM-HTGEKPYKCTECGKAFMRSSSLIIHQ-RIHTE 580

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDY 457
           EK + C EC  +   K  L  H  +HTGEKP+KC  C+     +  L +H   H+  K Y
Sbjct: 581 EKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKPY 640

Query: 458 MCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KSLMCEV 516
            C +CG   + K YL VH R H G+  Y+CN+C        QL+ H+ RH G K   C  
Sbjct: 641 KCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNE 700

Query: 517 CAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCA 576
           C            H  +  H G     + C+ C         V  H+   H+  + + C 
Sbjct: 701 CGKVFTSNSGFNTHQRT--HTGEKP--FKCNDCGKAFSQMVHVTEHQKI-HSGEKPYKCD 755

Query: 577 LCDYRTFSNTTLLFHKRKAHGYVP 600
           +C       + L  H R   G  P
Sbjct: 756 VCGKAFRRGSYLTVHWRTHTGEKP 779



 Score =  160 bits (406), Expect = 7e-39
 Identities = 115/449 (25%), Positives = 176/449 (39%), Gaps = 26/449 (5%)

Query: 156 TESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG 215
           T +  K + C EC + F + ++L +H  +H  +   +C  C K F + S L  H      
Sbjct: 297 THTKEKPYECNECGKTFSQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTK 356

Query: 216 EKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSH 275
           EK + C +C  S  +   LN+H      +        Y C  C + F     L  H ++H
Sbjct: 357 EKPYQCNVCGKSFSQCARLNQHQRIQTGE------KPYKCSECGKAFSDKSKLARHQETH 410

Query: 276 TAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEA 335
                    P +C  + C  A  ++     H K     +  +C  + C   F        
Sbjct: 411 NGEK-----PYKC--DDCGKAFRNKSYLSVHQKTHTEEKPYQC--NECGKSFKNTTIFNV 461

Query: 336 HHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVG 392
           H + H     F C  C  A  +      H +  H G +   C  C  A FN +A      
Sbjct: 462 HQRIHTGEKPFRCNECGKAYRSNSSLIVHIRT-HTGEKPYECNECGKA-FNRIANFTEHQ 519

Query: 393 KMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHS 452
           ++H  EK ++C EC  A  +   L  H  +HTGEKP+KC  C       S L  H   H+
Sbjct: 520 RIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHT 579

Query: 453 NTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQG-KS 511
             K Y+C ECG   + K +L VH R H G+  Y+C  C     +   L  H+  H G K 
Sbjct: 580 EEKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKP 639

Query: 512 LMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLR 571
             C    + C + +  + ++       T    Y C+ C     +   +  H+  +HT  +
Sbjct: 640 YKC----YDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQR-RHTGEK 694

Query: 572 EFHCALCDYRTFSNTTLLFHKRKAHGYVP 600
            + C  C     SN+    H+R   G  P
Sbjct: 695 PYKCNECGKVFTSNSGFNTHQRTHTGEKP 723



 Score =  150 bits (380), Expect = 8e-36
 Identities = 97/373 (26%), Positives = 149/373 (39%), Gaps = 36/373 (9%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C EC + F +  +  EH  +H  +   +C  C K F + S L  H     GEK + 
Sbjct: 498 KPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYK 557

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDT----------------------YACPVC 258
           C  C  + +  ++L  H     E+     ++                       Y C  C
Sbjct: 558 CTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDC 617

Query: 259 REEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVEC 318
              F     LKEH K HT        P +C+  G S+    +   I H +   G +  +C
Sbjct: 618 ERAFTKMVNLKEHQKIHTGVK-----PYKCYDCGKSFRT--KSYLIVHQRTHTGEKPYKC 670

Query: 319 RHHSCPMLFATAEAMEAHHKSHYA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCT 375
             + C   F     +  H + H     + C  C    ++   F  H++  H G +  +C 
Sbjct: 671 --NECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRT-HTGEKPFKCN 727

Query: 376 FCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCD 435
            C  A    V   +H  K+H+ EK ++C  C  A      L  H   HTGEKP+ C+ C 
Sbjct: 728 DCGKAFSQMVHVTEHQ-KIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECG 786

Query: 436 FTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCH 495
             C  +S L+ H   H+  + Y C ECG   +      VH+R H G+  Y+CN+C     
Sbjct: 787 KGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFR 846

Query: 496 RADQLSSHKLRHQ 508
            +  L+ H+  HQ
Sbjct: 847 SSSSLTVHQRIHQ 859



 Score =  137 bits (345), Expect = 9e-32
 Identities = 102/377 (27%), Positives = 154/377 (40%), Gaps = 73/377 (19%)

Query: 1137 CSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEG 1196
            C+ C      +++L +HQ R H         +P+L C +CG + +    +  H+R+ H G
Sbjct: 558  CTECGKAFMRSSSLIIHQ-RIHTEE------KPYL-CNECGESFRIKSHLTVHQRI-HTG 608

Query: 1197 VKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPT 1256
             KP++C  C+ + T+   L+ HQ  HTG+    C  C ++F T S L +H+         
Sbjct: 609  EKPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQ--------- 659

Query: 1257 HFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPA 1316
                                   H G   + C++CE  F++ + L  H  RRH       
Sbjct: 660  ---------------------RTHTGEKPYKCNECEKAFTNTSQLTVHQ-RRH------- 690

Query: 1317 PGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQ--HPRLECGACQEAFPSRLALDEHRR 1374
                  T E P  C+ CG +  S +    H R        +C  C +AF   + + EH++
Sbjct: 691  ------TGEKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVTEHQK 744

Query: 1375 --QQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFT 1432
                   ++C +C  A R        YL  H  T             G+ P  C  C   
Sbjct: 745  IHSGEKPYKCDVCGKAFRRG-----SYLTVHWRTHT-----------GEKPYTCKECGKG 788

Query: 1433 CRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADP 1492
            C     L  H + H G R YKC +C  + +     T H R+HTGEKPY C+ C  A    
Sbjct: 789  CITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSS 848

Query: 1493 SRLKYHMRIHKEERKYL 1509
            S L  H RIH+ E + +
Sbjct: 849  SSLTVHQRIHQRETQLI 865



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 66/269 (24%), Positives = 99/269 (36%), Gaps = 20/269 (7%)

Query: 161 KTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHH 220
           K + C +C+R F K  +L EH  +H      +C +C K F +KS L  H     GEK + 
Sbjct: 610 KPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYK 669

Query: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
           C  C  +    + L  H      +        Y C  C + F  +     H ++HT    
Sbjct: 670 CNECEKAFTNTSQLTVHQRRHTGE------KPYKCNECGKVFTSNSGFNTHQRTHTGEK- 722

Query: 281 AEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSH 340
               P +C    C  A        +H K   G +  +C    C   F     +  H ++H
Sbjct: 723 ----PFKC--NDCGKAFSQMVHVTEHQKIHSGEKPYKC--DVCGKAFRRGSYLTVHWRTH 774

Query: 341 YA---FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH 397
                + C  C   C        H++  H G    +C  C  A      +  H+ +MH  
Sbjct: 775 TGEKPYTCKECGKGCITLSQLTLHQRI-HTGERPYKCEECGKAFRTNSDFTVHL-RMHTG 832

Query: 398 EKIHQCPECNFATAHKRVLIRHMLLHTGE 426
           EK ++C EC  A      L  H  +H  E
Sbjct: 833 EKPYKCNECGKAFRSSSSLTVHQRIHQRE 861



 Score = 34.7 bits (78), Expect = 0.81
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C     R  +L +H R   +   +P LC ECG SF+ +  L+ H
Sbjct: 554 KPYKCTECGKAFMRSSSLIIHQRIHTE--EKPYLCNECGESFRIKSHLTVH 602



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 834 RAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           + ++C  C    R +  L++H +T  +   +P  C ECG SFK     + H
Sbjct: 414 KPYKCDDCGKAFRNKSYLSVHQKTHTE--EKPYQCNECGKSFKNTTIFNVH 462



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 6/53 (11%)

Query: 834 RAFRCPHC--PFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTH 884
           R ++C  C   F T  +  ++L   TG     +P  C ECG +F+    L+ H
Sbjct: 806 RPYKCEECGKAFRTNSDFTVHLRMHTG----EKPYKCNECGKAFRSSSSLTVH 854


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,053,159
Number of Sequences: 37866
Number of extensions: 5335204
Number of successful extensions: 127718
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1108
Number of HSP's successfully gapped in prelim test: 750
Number of HSP's that attempted gapping in prelim test: 25935
Number of HSP's gapped (non-prelim): 34199
length of query: 1687
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1571
effective length of database: 13,855,062
effective search space: 21766302402
effective search space used: 21766302402
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.