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Search of human proteins with 157502179
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502179 tetratricopeptide repeat domain 21A isoform 1
[Homo sapiens]
(1321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo... 2624 0.0
gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo... 2617 0.0
gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens] 1373 0.0
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 51 6e-06
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 50 1e-05
gi|83415184 transmembrane and tetratricopeptide repeat containin... 50 1e-05
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 45 6e-04
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 45 6e-04
gi|34304360 nephrocystin 3 [Homo sapiens] 44 8e-04
gi|22749211 transmembrane and tetratricopeptide repeat containin... 44 0.001
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 42 0.004
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 42 0.004
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 40 0.019
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 39 0.025
gi|118402596 cell division cycle protein 23 [Homo sapiens] 39 0.043
gi|224809432 transmembrane and tetratricopeptide repeat containi... 38 0.056
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens] 37 0.096
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 37 0.16
gi|17149828 NMDA receptor regulated 1 [Homo sapiens] 37 0.16
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 36 0.21
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 36 0.21
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 36 0.21
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 36 0.21
gi|15619013 43 kD receptor-associated protein of the synapse iso... 35 0.48
gi|209976994 adenylate cyclase 10 [Homo sapiens] 35 0.62
gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens] 35 0.62
gi|4503729 FK506 binding protein 52 [Homo sapiens] 34 1.1
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 33 1.4
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 33 1.4
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 33 1.4
>gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo
sapiens]
Length = 1321
Score = 2624 bits (6802), Expect = 0.0
Identities = 1321/1321 (100%), Positives = 1321/1321 (100%)
Query: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
Sbjct: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
Query: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL
Sbjct: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
Query: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV
Sbjct: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
Query: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI
Sbjct: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
Query: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK
Sbjct: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
Query: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA
Sbjct: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
Query: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK
Sbjct: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
Query: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV
Sbjct: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
Query: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHL 540
SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHL
Sbjct: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHL 540
Query: 541 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 600
LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI
Sbjct: 541 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 600
Query: 601 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 660
KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE
Sbjct: 601 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 660
Query: 661 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 720
NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR
Sbjct: 661 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 720
Query: 721 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 780
ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT
Sbjct: 721 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 780
Query: 781 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 840
EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC
Sbjct: 781 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 840
Query: 841 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 900
LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY
Sbjct: 841 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 900
Query: 901 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 960
LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA
Sbjct: 901 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 960
Query: 961 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1020
SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK
Sbjct: 961 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1020
Query: 1021 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1080
VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV
Sbjct: 1021 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1080
Query: 1081 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1140
VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE
Sbjct: 1081 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1140
Query: 1141 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1200
KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED
Sbjct: 1141 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1200
Query: 1201 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1260
LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK
Sbjct: 1201 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1260
Query: 1261 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1320
LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR
Sbjct: 1261 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1320
Query: 1321 P 1321
P
Sbjct: 1321 P 1321
>gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo
sapiens]
Length = 1320
Score = 2617 bits (6784), Expect = 0.0
Identities = 1320/1321 (99%), Positives = 1320/1321 (99%), Gaps = 1/1321 (0%)
Query: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
Sbjct: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
Query: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL
Sbjct: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
Query: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV
Sbjct: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
Query: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI
Sbjct: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
Query: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK
Sbjct: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
Query: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA
Sbjct: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
Query: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK
Sbjct: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
Query: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV
Sbjct: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
Query: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHL 540
SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS ELENAQSILQRCLELDPASVDAHL
Sbjct: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-ELENAQSILQRCLELDPASVDAHL 539
Query: 541 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 600
LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI
Sbjct: 540 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 599
Query: 601 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 660
KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE
Sbjct: 600 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 659
Query: 661 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 720
NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR
Sbjct: 660 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 719
Query: 721 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 780
ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT
Sbjct: 720 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 779
Query: 781 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 840
EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC
Sbjct: 780 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 839
Query: 841 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 900
LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY
Sbjct: 840 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 899
Query: 901 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 960
LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA
Sbjct: 900 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 959
Query: 961 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1020
SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK
Sbjct: 960 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1019
Query: 1021 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1080
VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV
Sbjct: 1020 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1079
Query: 1081 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1140
VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE
Sbjct: 1080 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1139
Query: 1141 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1200
KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED
Sbjct: 1140 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1199
Query: 1201 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1260
LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK
Sbjct: 1200 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1259
Query: 1261 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1320
LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR
Sbjct: 1260 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1319
Query: 1321 P 1321
P
Sbjct: 1320 P 1320
>gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens]
Length = 1316
Score = 1373 bits (3555), Expect = 0.0
Identities = 677/1315 (51%), Positives = 942/1315 (71%), Gaps = 13/1315 (0%)
Query: 12 IIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAISDLESIRHHPDV 71
I YY QE+YFHHV A+ G++++ +DPV +F+ AYG L E Q+A+ + E+I++ DV
Sbjct: 10 INYYCQERYFHHVLLVASEGIKRYGSDPVFRFYHAYGTLMEGKTQEALREFEAIKNKQDV 69
Query: 72 SLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFLWLIGRHDKAKE 131
SLCS +ALIYAHK DREAI E + +KE RK ALY+AGLFLW IGRHDKA+E
Sbjct: 70 SLCSLLALIYAHKMSPNPDREAILESDARVKEQRKGAGEKALYHAGLFLWHIGRHDKARE 129
Query: 132 YIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDVLGLMGKAMYFM 191
YIDRM+KIS G ++ +VL+ W+D+T K KKA++Y E+G+QD D L+GKA
Sbjct: 130 YIDRMIKISDGSKQGHVLKAWLDITRGKEPYTKKALKYFEEGLQDGNDTFALLGKAQCLE 189
Query: 192 MQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRILEKDESNIDAC 251
M+QNYS ALE VNQI V SFLPA V KM+L LA QDW+QTVE R+L +D N++A
Sbjct: 190 MRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWDQTVETAQRLLLQDSQNVEAL 249
Query: 252 QILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLKKIIVVSRLCGS 311
++ ++ + REG++ +KA+ + NL L+ EP+N L + SR CG
Sbjct: 250 RMQALYYVCREGDI--------EKASTKLENLGNTLDAMEPQNAQLFYNITLAFSRTCGR 301
Query: 312 HQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGL 371
Q+IL + + +ER F P ATELGY IL+ +VKEAL WY AM LD+ ++ L
Sbjct: 302 SQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVKEALKWYKTAMTLDETSVSAL 361
Query: 372 TGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKE 431
G I C ++EG L++A+ +LEFL E+Q+S+GKS LI+L A+L +K+K +EE LL +
Sbjct: 362 VGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLHAVLAMKKNKRQEEVINLLND 421
Query: 432 AVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVIL 491
++ HFS ++G+PLG +YFEKL+P FL+ I EYL FCP QP PGQ + PLL++ +L
Sbjct: 422 VLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPMQPASPGQPLCPLLRRCISVL 481
Query: 492 NPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMCQIYLAQGN 551
VV+ P L+ ++L+A+V+Y SG++E A + LQ CLE +P+ DAHLL+ Q+YL+Q
Sbjct: 482 ETVVRTVPGLLQTVFLIAKVKYLSGDIEAAFNNLQHCLEHNPSYADAHLLLAQVYLSQEK 541
Query: 552 FGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKK---E 608
+C LEL +S++F+VRD+PLYHLIKA++ K G+ +AIKTL M + LP +K+
Sbjct: 542 VKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMGEIADAIKTLHMAMSLPGMKRIGAS 601
Query: 609 EGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANV 668
K + V S R SI LEL++ RLNGE HEATKV+QD I+EF GT EE R+TIAN
Sbjct: 602 TKSKDRKTEVDTSHRLSIFLELIDVHRLNGEQHEATKVLQDAIHEFSGTSEEVRVTIANA 661
Query: 669 DLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG 728
DL L++G+++ AL++L+N+ +Q ++EAREKMA+IYL+ +D+ LYI C+RE+ E +
Sbjct: 662 DLALAQGDIERALSILQNVTAEQPYFIEAREKMADIYLKHRKDKMLYITCFREIAERMAN 721
Query: 729 PHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEA 788
P + LLLGDA M+ILEPE+A+ Y++A QNP D +LAS++G A +K H Y+ AI YYEA
Sbjct: 722 PRSFLLLGDAYMNILEPEEAIVAYEQALNQNPKDGTLASKMGKALIKTHNYSMAITYYEA 781
Query: 789 AQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVY 848
A K +++LC DL +LLLKLK +KAEKVL+ AL H+ V ++ ++M D +C +LLAKVY
Sbjct: 782 ALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQHALAHEPVNELSALMEDGRCQVLLAKVY 841
Query: 849 -KSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYD 907
K K I L +A +LQ+R+LKRV +EQP+ +P+QK LAA IC + A+H +A+++Y+
Sbjct: 842 SKMEKLGDAITALQQARELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYE 901
Query: 908 KAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADL 967
KA++ Y++ + TDNK+MLELA+LYL Q D C + CA+LLQ++Q++E A+++MADL
Sbjct: 902 KAIKFYREALVHCETDNKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADL 961
Query: 968 MFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPL 1027
MFRKQ +E A+ Q+LE+ PDN++ L +LIDLLRR GKLED+P FF +A+K +SR L
Sbjct: 962 MFRKQDYEQAVFHLQQLLERKPDNYMTLSRLIDLLRRCGKLEDVPRFFSMAEKRNSRAKL 1021
Query: 1028 EPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFE 1087
EPGF YC+G+Y W+ G+PN+AL+ NKARKD WGQ+A+Y+M++ICLNPDNE VGGE FE
Sbjct: 1022 EPGFQYCKGLYLWYTGEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFE 1081
Query: 1088 N-QGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEA 1146
N G N EK+E Q V TAEKLL+E P + QLR+++ C +AT++K+N+E
Sbjct: 1082 NLDGDLGNSTEKQESVQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQ 1141
Query: 1147 ALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDLEKSWL 1206
AL +F +IA +EK+ +PALL +A AY+ LKQ P+AR QLKR+AK W +AE+ EKSWL
Sbjct: 1142 ALNTFTEIAASEKEHIPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFEKSWL 1201
Query: 1207 LLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYS 1266
LLADIY Q +K+D+A +LL+RC+++N+SC KAYEYMG+IMEKEQ+Y DA NY++AWKYS
Sbjct: 1202 LLADIYIQSAKYDMAEDLLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYS 1261
Query: 1267 HHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP 1321
+ NPA+G+KLAFNYLK K++V++I+IC+ VL HP YPKIR++IL+KAR SLRP
Sbjct: 1262 NRTNPAVGYKLAFNYLKAKRYVDSIDICHQVLEAHPTYPKIRKDILDKARASLRP 1316
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 51.2 bits (121), Expect = 6e-06
Identities = 117/600 (19%), Positives = 236/600 (39%), Gaps = 88/600 (14%)
Query: 734 LLGDALMSILEPEK--ALEVYDEAYRQNPH-DASLASRIGHAYVKAHQYTEAIEYYEAAQ 790
LLG A +S + + AL Y +A R NP A + +GH +VK ++ +A + A
Sbjct: 166 LLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRAL 225
Query: 791 KINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALE-----HDIVQDIPSMMNDVKCLLLLA 845
++N + C L L+ NK +K ++ + I P ++N +
Sbjct: 226 ELNSK---CVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFK 282
Query: 846 KVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE 905
K Y + A+ N ++ + A C Q A + +++
Sbjct: 283 KDYSKVQHLALHAFHNTEVEA---------------------MQAESCYQLARSFHVQED 321
Query: 906 YDKAVQSYKDVFSYLPTDNKV-MLELAQLYLLQGHLDLCEQHC--AILLQTEQNHETASV 962
YD+A Q Y + + + L Q+Y+ +G + Q C +L N+ET +
Sbjct: 322 YDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQ-CFEKVLKAYPNNYETMKI 380
Query: 963 L--MADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFE---- 1016
L + ++K + A +V E+ PD+ +L +L ++ + A+
Sbjct: 381 LGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRI 440
Query: 1017 LAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKF----LNKARKDSTWGQSAIYHMVQI 1072
L +KV + VP E N G + +G EA K+ L++A+ ++ + Y+ + +
Sbjct: 441 LQEKVQADVPPEILNNV--GALHFRLGNLGEAKKYFLASLDRAKAEAEHDEH-YYNAISV 497
Query: 1073 CLNPDNEVVGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQG 1132
+ + + E AE Y + +LRE H + LRL
Sbjct: 498 TTSYNLARLYEAMCEFHEAEKLY--------------KNILRE---HPNYVDCYLRL--- 537
Query: 1133 LCRLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTP 1192
R+K N A F + Q +D A + ++ ++ + + +R+ K P
Sbjct: 538 --GAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQP 595
Query: 1193 WVLSEAEDLEKSWLLLADIYCQ------------GSKFDLALELLRRCVQYNKSCYKAYE 1240
S+ S L L +++ Q D AL + ++ ++ + A
Sbjct: 596 STQSDT----YSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAAN 651
Query: 1241 YMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLRE 1300
+G ++ + +++A + + + + + LA Y++ K+++ A+++ + LR+
Sbjct: 652 GIGAVLAHKGYFREARDVFAQVREATADISD-VWLNLAHIYVEQKQYISAVQMYENCLRK 710
Score = 37.7 bits (86), Expect = 0.073
Identities = 70/327 (21%), Positives = 130/327 (39%), Gaps = 54/327 (16%)
Query: 731 TSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQ 790
TS L ++ E +A ++Y R++P+ R+G + EA ++++ A
Sbjct: 499 TSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEAL 558
Query: 791 KINGQDF--LCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVY 848
+IN QD +G L L ++ +K ++ L+ PS +D +L L V+
Sbjct: 559 QIN-QDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQ------PSTQSDTYSMLALGNVW 611
Query: 849 ------KSHKKEAVIETLNKALDLQSRIL-------------------KRVPLEQPEMIP 883
+ +E ++AL + ++L K E ++
Sbjct: 612 LQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFA 671
Query: 884 SQKQLAASIC---IQFAEHYLAEKEYDKAVQSYKDVFS--YLPTDNKVMLELAQLYLLQG 938
++ A I + A Y+ +K+Y AVQ Y++ Y + +V+L LA+ G
Sbjct: 672 QVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCG 731
Query: 939 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 998
L C+Q LL+ + +VLM ++ Q+ L VL+ N L
Sbjct: 732 KLQECKQ---TLLKARHVAPSDTVLMFNVALVLQR------LATSVLKDEKSN------L 776
Query: 999 IDLLRRSGKLEDIPAFFELAKKVSSRV 1025
++L +LE +F KV ++
Sbjct: 777 KEVLNAVKELELAHRYFSYLSKVGDKM 803
Score = 32.3 bits (72), Expect = 3.1
Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 16/182 (8%)
Query: 701 MANIYLQTL--------RDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPE----KA 748
+ N++LQTL +++R R + L +L + + ++L + +A
Sbjct: 607 LGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREA 666
Query: 749 LEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQK---INGQDFLCCDLGKL 805
+V+ + + + + H YV+ QY A++ YE + + + L +
Sbjct: 667 RDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARA 726
Query: 806 LLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALD 865
L K K+ + ++ L +A H D M N L LA +K + E LN +
Sbjct: 727 LFKCGKLQECKQTLLKA-RHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKE 785
Query: 866 LQ 867
L+
Sbjct: 786 LE 787
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 50.4 bits (119), Expect = 1e-05
Identities = 57/257 (22%), Positives = 108/257 (42%), Gaps = 34/257 (13%)
Query: 746 EKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDF-LCCDLGK 804
+++LE++ +P A ++ + ++ AIE Y A K+N +D+ + +LG
Sbjct: 84 QESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGV 143
Query: 805 LLLKLKKVNKAEKVLKQAL---EHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLN 861
+ LK+ NKA+ L AL HD+ ++L K+ H E L+
Sbjct: 144 CYIYLKQFNKAQDQLHNALNLNRHDLT------------YIMLGKI---HLLEG---DLD 185
Query: 862 KALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLP 921
KA+++ + ++ P E E++ + L YL Y KA + + +Y P
Sbjct: 186 KAIEVYKKAVEFSP-ENTELLTTLGLL-----------YLQLGIYQKAFEHLGNALTYDP 233
Query: 922 TDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLY 981
T+ K +L + G D+ ++ + F K+K+ AAI+
Sbjct: 234 TNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCL 293
Query: 982 HQVLEKAPDNFLVLHKL 998
+ AP ++ +L+ L
Sbjct: 294 KRANYLAPFDWKILYNL 310
Score = 34.3 bits (77), Expect = 0.81
Identities = 44/205 (21%), Positives = 88/205 (42%), Gaps = 9/205 (4%)
Query: 585 KAGDYPEAIKTLKMVIKLPALKK--EEGRKFLRPSVQPSQRASILLELVEAL--RLNGEL 640
KA ++P ++ +I L ++K E + ++ +Q +Q V+AL RL G +
Sbjct: 25 KAPEFP-ILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNI 83
Query: 641 HEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREK 700
E+ ++ Q T +N +A +L K + + L ++ +
Sbjct: 84 QESLELFQ-TCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLG 142
Query: 701 MANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNP 760
+ IYL+ + + L H T ++LG + + +KA+EVY +A +P
Sbjct: 143 VCYIYLKQFNKAQDQLHNALNLNRH---DLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSP 199
Query: 761 HDASLASRIGHAYVKAHQYTEAIEY 785
+ L + +G Y++ Y +A E+
Sbjct: 200 ENTELLTTLGLLYLQLGIYQKAFEH 224
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 50.4 bits (119), Expect = 1e-05
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 36/361 (9%)
Query: 658 PEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIR 717
P+ NR +L+ S+ + A+ +L++ + + +A +A++ + R +
Sbjct: 437 PQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAE-E 495
Query: 718 CYRELCEHLPGP---HTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYV 774
Y+ ++ P H + G L+ PEKA+ Y +A + +P +G Y
Sbjct: 496 IYQTGIKNCPDSSDLHNNY--GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYR 553
Query: 775 KAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSM 834
+ + A E+Y+ A ++ + + LG L + +A ++ ++A +
Sbjct: 554 SLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAA------LQPS 607
Query: 835 MNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICI 894
+++ L KEA ++ + E+ + + L+A
Sbjct: 608 QRELRLALAQVLAVMGQTKEA------------EKMTNHIVSEETGCLECYRLLSAI--- 652
Query: 895 QFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLEL----AQLYLLQGHLDLCEQHCAIL 950
Y ++ +DKA+ + P D KV+ EL Q LD + +
Sbjct: 653 -----YSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVA 707
Query: 951 LQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLED 1010
+Q + A + M + K K+ +A Y + L+ PD+ L+ L L R +L++
Sbjct: 708 VQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQE 767
Query: 1011 I 1011
+
Sbjct: 768 V 768
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 44.7 bits (104), Expect = 6e-04
Identities = 65/282 (23%), Positives = 114/282 (40%), Gaps = 21/282 (7%)
Query: 755 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFL--CCDLGKLLLKLKKV 812
A +QNP A S +G+ Y + Q EAIE+Y A ++ DF+ +L L+ +
Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK-PDFIDGYINLAAALVAAGDM 129
Query: 813 NKAEKVLKQALEHDIVQDIPSMMNDVKCLL-----------LLAKVYKSHKKEAVI-ETL 860
A + AL+++ D+ + +D+ LL K ++ AV L
Sbjct: 130 EGAVQAYVSALQYN--PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL 187
Query: 861 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE-YDKAVQSYKDVFSY 919
+ Q I + + + L A I + + L E +D+AV +Y S
Sbjct: 188 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLG---NVLKEARIFDRAVAAYLRALSL 244
Query: 920 LPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAIN 979
P V LA +Y QG +DL ++ + + A +A+ + K A +
Sbjct: 245 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 304
Query: 980 LYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1021
Y+ L P + L+ L ++ R G +E+ + A +V
Sbjct: 305 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 346
Score = 40.8 bits (94), Expect = 0.009
Identities = 64/304 (21%), Positives = 125/304 (41%), Gaps = 23/304 (7%)
Query: 735 LGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKING 794
LG+ + ++A+E Y A R P + A V A A++ Y +A + N
Sbjct: 85 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYN- 143
Query: 795 QDFLCC--DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLL-LLAKVYKS- 850
D C DLG LL L ++ +A+ +A+E + +++ C+ +++ +
Sbjct: 144 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ--PNFAVAWSNLGCVFNAQGEIWLAI 201
Query: 851 -HKKEAVI---ETLNKALDL-----QSRILKRVP---LEQPEMIPSQKQLAASICIQFAE 898
H ++AV L+ ++L ++RI R L + P+ + ++ + E
Sbjct: 202 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 261
Query: 899 HYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE 958
L D A+ +Y+ P LA +G + E L+ H
Sbjct: 262 QGLI----DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 317
Query: 959 TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELA 1018
+ +A++ + E A+ LY + LE P+ L +L++ GKL++ ++ A
Sbjct: 318 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 377
Query: 1019 KKVS 1022
++S
Sbjct: 378 IRIS 381
Score = 37.0 bits (84), Expect = 0.13
Identities = 70/344 (20%), Positives = 131/344 (38%), Gaps = 43/344 (12%)
Query: 331 PSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEA--- 387
P + LG ++ + Q++EA+ Y A++L D + G + + G +E A
Sbjct: 76 PLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQA 135
Query: 388 -----EYRLEF------LKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELH 436
+Y + L + K+LG+ E +A K + A+ +
Sbjct: 136 YVSALQYNPDLYCVRSDLGNLLKALGRLE-----EAKACYLKAIETQPNFAVAWSNLGCV 190
Query: 437 FSSMQGIPLGSEYFEK---LDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNP 493
F++ I L +FEK LDP FL L K+ R+ + V+ L+ +++ N
Sbjct: 191 FNAQGEIWLAIHHFEKAVTLDPNFLDAYIN--LGNVLKEARIFDRAVAAYLRALSLSPNH 248
Query: 494 VVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFG 553
V +A V Y G ++ A +R +EL P DA+ + +G+
Sbjct: 249 AVVHGN--------LACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA 300
Query: 554 MCFHC----LELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEE 609
C L L +H + + A + G+ EA++ + +++
Sbjct: 301 EAEDCYNTALRLCPTHADSLNN-------LANIKREQGNIEEAVRLYRKALEVFPEFAAA 353
Query: 610 GRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINE 653
Q + L+ EA+R++ +A M +T+ E
Sbjct: 354 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE 397
Score = 35.0 bits (79), Expect = 0.48
Identities = 60/297 (20%), Positives = 114/297 (38%), Gaps = 29/297 (9%)
Query: 516 GELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLY 575
G LE A++ + +E P A + ++ AQG + H E V+ + D
Sbjct: 161 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA--- 217
Query: 576 HLIKARALNKAGDYPEAIKTLKMVIKLP-----------ALKKEEGRKFLRPSVQPSQRA 624
++ L +A + A+ + L + E+G + ++ +RA
Sbjct: 218 YINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG--LIDLAIDTYRRA 275
Query: 625 SIL--------LELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN 676
L L AL+ G + EA +T T ++ +AN+ +GN
Sbjct: 276 IELQPHFPDAYCNLANALKEKGSVAEAEDCY-NTALRLCPTHADSLNNLANIKR--EQGN 332
Query: 677 VDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLL-L 735
++ A+ + R L + A +A++ Q + + + Y+E P + +
Sbjct: 333 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH-YKEAIRISPTFADAYSNM 391
Query: 736 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 792
G+ L + + + AL+ Y A + NP A S + + + EAI Y A K+
Sbjct: 392 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 448
Score = 31.6 bits (70), Expect = 5.3
Identities = 42/196 (21%), Positives = 72/196 (36%), Gaps = 14/196 (7%)
Query: 484 LKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMC 543
L++ + ++ +P D M +++ A R ++++PA DAH +
Sbjct: 367 LQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLA 426
Query: 544 QIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLP 603
I+ GN + D P + A L D+ + + +K ++ +
Sbjct: 427 SIHKDSGNIPEAIASYRTALKLK---PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIV 483
Query: 604 ALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRI 663
A + E+ R PSV P S+L L R + D IN P E+
Sbjct: 484 ADQLEKNR---LPSVHPHH--SMLYPLSHGFR-KAIAERHGNLCLDKINVLHKPPYEH-- 535
Query: 664 TIANVDLVLSKGNVDV 679
DL LS G + V
Sbjct: 536 ---PKDLKLSDGRLRV 548
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 44.7 bits (104), Expect = 6e-04
Identities = 65/282 (23%), Positives = 114/282 (40%), Gaps = 21/282 (7%)
Query: 755 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFL--CCDLGKLLLKLKKV 812
A +QNP A S +G+ Y + Q EAIE+Y A ++ DF+ +L L+ +
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK-PDFIDGYINLAAALVAAGDM 139
Query: 813 NKAEKVLKQALEHDIVQDIPSMMNDVKCLL-----------LLAKVYKSHKKEAVI-ETL 860
A + AL+++ D+ + +D+ LL K ++ AV L
Sbjct: 140 EGAVQAYVSALQYN--PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL 197
Query: 861 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE-YDKAVQSYKDVFSY 919
+ Q I + + + L A I + + L E +D+AV +Y S
Sbjct: 198 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLG---NVLKEARIFDRAVAAYLRALSL 254
Query: 920 LPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAIN 979
P V LA +Y QG +DL ++ + + A +A+ + K A +
Sbjct: 255 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 314
Query: 980 LYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1021
Y+ L P + L+ L ++ R G +E+ + A +V
Sbjct: 315 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356
Score = 40.8 bits (94), Expect = 0.009
Identities = 64/304 (21%), Positives = 125/304 (41%), Gaps = 23/304 (7%)
Query: 735 LGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKING 794
LG+ + ++A+E Y A R P + A V A A++ Y +A + N
Sbjct: 95 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYN- 153
Query: 795 QDFLCC--DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLL-LLAKVYKS- 850
D C DLG LL L ++ +A+ +A+E + +++ C+ +++ +
Sbjct: 154 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ--PNFAVAWSNLGCVFNAQGEIWLAI 211
Query: 851 -HKKEAVI---ETLNKALDL-----QSRILKRVP---LEQPEMIPSQKQLAASICIQFAE 898
H ++AV L+ ++L ++RI R L + P+ + ++ + E
Sbjct: 212 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 271
Query: 899 HYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE 958
L D A+ +Y+ P LA +G + E L+ H
Sbjct: 272 QGLI----DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 327
Query: 959 TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELA 1018
+ +A++ + E A+ LY + LE P+ L +L++ GKL++ ++ A
Sbjct: 328 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 387
Query: 1019 KKVS 1022
++S
Sbjct: 388 IRIS 391
Score = 37.0 bits (84), Expect = 0.13
Identities = 70/344 (20%), Positives = 131/344 (38%), Gaps = 43/344 (12%)
Query: 331 PSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEA--- 387
P + LG ++ + Q++EA+ Y A++L D + G + + G +E A
Sbjct: 86 PLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQA 145
Query: 388 -----EYRLEF------LKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELH 436
+Y + L + K+LG+ E +A K + A+ +
Sbjct: 146 YVSALQYNPDLYCVRSDLGNLLKALGRLE-----EAKACYLKAIETQPNFAVAWSNLGCV 200
Query: 437 FSSMQGIPLGSEYFEK---LDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNP 493
F++ I L +FEK LDP FL L K+ R+ + V+ L+ +++ N
Sbjct: 201 FNAQGEIWLAIHHFEKAVTLDPNFLDAYIN--LGNVLKEARIFDRAVAAYLRALSLSPNH 258
Query: 494 VVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFG 553
V +A V Y G ++ A +R +EL P DA+ + +G+
Sbjct: 259 AVVHGN--------LACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA 310
Query: 554 MCFHC----LELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEE 609
C L L +H + + A + G+ EA++ + +++
Sbjct: 311 EAEDCYNTALRLCPTHADSLNN-------LANIKREQGNIEEAVRLYRKALEVFPEFAAA 363
Query: 610 GRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINE 653
Q + L+ EA+R++ +A M +T+ E
Sbjct: 364 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE 407
Score = 35.0 bits (79), Expect = 0.48
Identities = 60/297 (20%), Positives = 114/297 (38%), Gaps = 29/297 (9%)
Query: 516 GELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLY 575
G LE A++ + +E P A + ++ AQG + H E V+ + D
Sbjct: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA--- 227
Query: 576 HLIKARALNKAGDYPEAIKTLKMVIKLP-----------ALKKEEGRKFLRPSVQPSQRA 624
++ L +A + A+ + L + E+G + ++ +RA
Sbjct: 228 YINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG--LIDLAIDTYRRA 285
Query: 625 SIL--------LELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN 676
L L AL+ G + EA +T T ++ +AN+ +GN
Sbjct: 286 IELQPHFPDAYCNLANALKEKGSVAEAEDCY-NTALRLCPTHADSLNNLANIKR--EQGN 342
Query: 677 VDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLL-L 735
++ A+ + R L + A +A++ Q + + + Y+E P + +
Sbjct: 343 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH-YKEAIRISPTFADAYSNM 401
Query: 736 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 792
G+ L + + + AL+ Y A + NP A S + + + EAI Y A K+
Sbjct: 402 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Score = 31.6 bits (70), Expect = 5.3
Identities = 42/196 (21%), Positives = 72/196 (36%), Gaps = 14/196 (7%)
Query: 484 LKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHLLMC 543
L++ + ++ +P D M +++ A R ++++PA DAH +
Sbjct: 377 LQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLA 436
Query: 544 QIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLP 603
I+ GN + D P + A L D+ + + +K ++ +
Sbjct: 437 SIHKDSGNIPEAIASYRTALKLK---PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIV 493
Query: 604 ALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRI 663
A + E+ R PSV P S+L L R + D IN P E+
Sbjct: 494 ADQLEKNR---LPSVHPHH--SMLYPLSHGFR-KAIAERHGNLCLDKINVLHKPPYEH-- 545
Query: 664 TIANVDLVLSKGNVDV 679
DL LS G + V
Sbjct: 546 ---PKDLKLSDGRLRV 558
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 44.3 bits (103), Expect = 8e-04
Identities = 65/293 (22%), Positives = 128/293 (43%), Gaps = 29/293 (9%)
Query: 746 EKALEVYDEAY-RQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGK 804
++ALE+ + AY +P+ A + Y K ++Y +A + + + KI+ K
Sbjct: 1009 KQALEISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQ---------K 1059
Query: 805 LLLKLKKVNKAEKVLKQALEHD---IVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLN 861
+ K + + ++AL+ + + +D P + L +L Y + E + L
Sbjct: 1060 AIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVL--YYLQNNLETADQFLK 1117
Query: 862 KALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSY-L 920
++L+++ R+L + P+ S LAA +C + ++ AE+ Y++A+ + +
Sbjct: 1118 RSLEMRERVLGP---DHPDCAQSLNNLAA-LCNEKKQYDKAEELYERALDIRRRALAPDH 1173
Query: 921 PTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNH--------ETASVLMADLMFRKQ 972
P+ + LA LY G LD + ++ Q TA V +A L + +
Sbjct: 1174 PSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMK 1233
Query: 973 KHEAAINLYHQVLEKAPDNFLVLHKLI-DLLRRSGKLEDIPAFFELAKKVSSR 1024
KH A+ LY + L+ D+ +H + + L+ L FE A ++ R
Sbjct: 1234 KHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKR 1286
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 43.9 bits (102), Expect = 0.001
Identities = 67/262 (25%), Positives = 113/262 (43%), Gaps = 46/262 (17%)
Query: 707 QTLRDRRLYIRCYRELCEHLPGPH------TSLL--LGDALMSILEPEKALEVYDEAYRQ 758
+T RR +++C E+L PH TS L LG E+AL VY EA ++
Sbjct: 576 RTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Query: 759 NPHD---ASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDL--GKLLLKLKKVN 813
P SL + +G AY++ + EA +Y + + + D + L GKLL + +
Sbjct: 636 MPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLR-SKTDHIPAHLTYGKLLALTGRKS 694
Query: 814 KAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKR 873
+AEK+ +A+E D P+ N C + H + ++E ++R+
Sbjct: 695 EAEKLFLKAIELD-----PTKGN---CYM--------HYGQFLLE--------EARL--- 727
Query: 874 VPLEQPEMIPSQKQL-AASICIQF-AEHYLAEKEYDKAVQSYKDVFSYL-PTDNKVMLEL 930
+E EM +L + + F A H L + ++A + Y D+ + L P ++ L
Sbjct: 728 --IEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNL 785
Query: 931 AQLYLLQGHLDLCEQHCAILLQ 952
+ L G L E + LQ
Sbjct: 786 GAILHLNGRLQKAEANYLRALQ 807
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
Query: 678 DVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG-PHTSLLLG 736
DVAL++L L A R+ + I+ ++ + P + LLG
Sbjct: 555 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 614
Query: 737 DALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ- 795
+ E +KAL + A R NP + +G Y K +++ A +++ A IN Q
Sbjct: 615 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 674
Query: 796 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHD 826
L C +G + LKK KA L +A+ D
Sbjct: 675 SVLLCHIGVVQHALKKSEKALDTLNKAIVID 705
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 33/158 (20%)
Query: 309 CGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEAL-------------- 354
C S Q + F +R P+Y + T LG+ F+L ++ +AL
Sbjct: 582 CFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 641
Query: 355 -LWYSEAM---KLDKDGMAGL-----------TGIILCHI--LEGHLEEAEYRLEFLKEV 397
WY M K +K +A + + ++LCHI ++ L+++E L+ L +
Sbjct: 642 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKA 701
Query: 398 QKSLGKSEVLIFLQA--LLMSRKHKGEEETTALLKEAV 433
K+ + F +A L + K+K + LK+ V
Sbjct: 702 IVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 739
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
Query: 678 DVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG-PHTSLLLG 736
DVAL++L L A R+ + I+ ++ + P + LLG
Sbjct: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608
Query: 737 DALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ- 795
+ E +KAL + A R NP + +G Y K +++ A +++ A IN Q
Sbjct: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668
Query: 796 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHD 826
L C +G + LKK KA L +A+ D
Sbjct: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVID 699
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 33/158 (20%)
Query: 309 CGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEAL-------------- 354
C S Q + F +R P+Y + T LG+ F+L ++ +AL
Sbjct: 576 CFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 635
Query: 355 -LWYSEAM---KLDKDGMAGL-----------TGIILCHI--LEGHLEEAEYRLEFLKEV 397
WY M K +K +A + + ++LCHI ++ L+++E L+ L +
Sbjct: 636 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKA 695
Query: 398 QKSLGKSEVLIFLQA--LLMSRKHKGEEETTALLKEAV 433
K+ + F +A L + K+K + LK+ V
Sbjct: 696 IVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens]
Length = 504
Score = 39.7 bits (91), Expect = 0.019
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 23/123 (18%)
Query: 1200 DLEKSWLLLADIYCQGSKFDLALELLRRCV---QYNKSC---YKAYEYMGFIMEKEQS-- 1251
D +++ ++ +Y Q +L+L +R C+ Q +K C YK + + ++E +
Sbjct: 220 DNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELI 279
Query: 1252 ----YKDAVTNYKLAWKYSHHANPAIGF-------KLAFNYLKDKKFVEAIEICNDVLRE 1300
Y DA + Y+ K P+I ++ + KD+K VEAI +C++VL+
Sbjct: 280 RDGRYTDATSKYESVMK----TEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQM 335
Query: 1301 HPD 1303
PD
Sbjct: 336 EPD 338
Score = 37.0 bits (84), Expect = 0.13
Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 14/113 (12%)
Query: 744 EPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLG 803
+P +A+ V E + P + + AY+ Y EAI+ YE AQ+ N D
Sbjct: 321 KPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQI---- 376
Query: 804 KLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAV 856
+ + KA+++LKQ+ + D + + N K ++ K+++K A+
Sbjct: 377 -----REGLEKAQRLLKQSQKRDYYKILGVKRNAKK-----QEIIKAYRKLAL 419
Score = 35.8 bits (81), Expect = 0.28
Identities = 70/350 (20%), Positives = 129/350 (36%), Gaps = 64/350 (18%)
Query: 670 LVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIY----LQTLRDRRL----------- 714
L+L +G +D A + + +L E +E + + +Q LR + L
Sbjct: 114 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAA 173
Query: 715 --YIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHA 772
++ E+C + L + + EP KA+ A + + +I
Sbjct: 174 IAFLDKILEVC--VWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTL 231
Query: 773 YVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKK-VNKAEKVLKQALEHDIVQDI 831
Y + + ++ K++ C K + KL K + AE++++ D
Sbjct: 232 YYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKY 291
Query: 832 PSMMNDVKCLLLLAKVYKSHKKEAVIETLNK------ALDLQSRILKRVPLEQPEMIPSQ 885
S+M + Y KE + +K A+ + S +L+ +P+ + +
Sbjct: 292 ESVMKTEPSIA----EYTVRSKERICHCFSKDEKPVEAIRVCSEVLQM----EPDNVNAL 343
Query: 886 KQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVM--LELAQLYLLQGHLDLC 943
K A E YL E+ YD+A+Q Y+ + D ++ LE AQ
Sbjct: 344 KDRA--------EAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQR---------- 385
Query: 944 EQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQV-LEKAPDNF 992
LL+ Q + +L R K + I Y ++ L+ PDNF
Sbjct: 386 ------LLKQSQKRDYYKILGVK---RNAKKQEIIKAYRKLALQWHPDNF 426
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 39.3 bits (90), Expect = 0.025
Identities = 78/395 (19%), Positives = 151/395 (38%), Gaps = 90/395 (22%)
Query: 736 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 795
G+ +S+ + AL+ Y EA + +PH+ L S AY K Y +A Y + + ++
Sbjct: 11 GNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKA--YEDGCKTVD-- 66
Query: 796 DFLCCDLGK-------LLLKLKKVNKAEKVLKQALEHD-----IVQDIPSM--------- 834
L D GK L L + +A++ ++ L+H+ + + + +M
Sbjct: 67 --LKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKF 124
Query: 835 MNDVKCLLLLAKVYKSHK----------KEAVIETLNKALDL-----QSRILKRV----- 874
MN L K+ + +E + + NK DL RI+ +
Sbjct: 125 MNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLG 184
Query: 875 --------------------PLEQPEMIPSQKQLAASICIQFAEHYLAEKEY-----DKA 909
P ++ + P ++ L + E L Y D A
Sbjct: 185 VDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTA 244
Query: 910 VQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQT-EQNHE------TASV 962
++ Y PT+ + A +Y +G + C + C ++ +N E A
Sbjct: 245 LKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYA 304
Query: 963 LMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVS 1022
+ + F+++K++ AI+ Y++ L + H+ D+L++ + E I E ++
Sbjct: 305 RIGNSYFKEEKYKDAIHFYNKSLAE--------HRTPDVLKKCQQAEKILKEQERLAYIN 356
Query: 1023 SRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARK 1057
+ LE +G C+ G +A+K +A K
Sbjct: 357 PDLALE---EKNKGNECFQKGDYPQAMKHYTEAIK 388
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 38.5 bits (88), Expect = 0.043
Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 33/306 (10%)
Query: 676 NVDVALNMLRNILPKQSCYMEAREKMANI-YLQTLRDRRLYIRCYRELCE-HLPGPHTSL 733
++D AL++ + + +E + +N+ Y+++++ Y+ LCE T
Sbjct: 278 DIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLA--HNLCEIDKYRVETCC 335
Query: 734 LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKIN 793
++G+ + EKA + A + NP + +GH Y++ + AI+ Y A ++N
Sbjct: 336 VIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN 395
Query: 794 GQDFLC-CDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHK 852
+D+ LG+ LK ++A H + ND + L+ L + Y
Sbjct: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRA--HQL------RPNDSRMLVALGECY---- 443
Query: 853 KEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQ- 911
E LN+ ++ + + + E + K A + Q E A + Y K +Q
Sbjct: 444 -----EKLNQLVEAKKCYWRAYAVGDVEKMALVK--LAKLHEQLTESEQAAQCYIKYIQD 496
Query: 912 --SYKDVFSYLPTDNKVMLELAQLYL---LQGHLDLCEQHCAILLQTEQNHETASVLMAD 966
S ++ +L ++ LAQ Y L C Q C T + E ++L
Sbjct: 497 IYSCGEIVEHL-EESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTRE--EGKALLRQI 553
Query: 967 LMFRKQ 972
L R Q
Sbjct: 554 LQLRNQ 559
>gi|224809432 transmembrane and tetratricopeptide repeat containing 3
[Homo sapiens]
Length = 914
Score = 38.1 bits (87), Expect = 0.056
Identities = 60/292 (20%), Positives = 120/292 (41%), Gaps = 26/292 (8%)
Query: 786 YEAAQKINGQDF-LCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLL 844
+ +A K+N + L ++G L K +A K QA H DI + MN +
Sbjct: 435 FMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQAT-HVQPDDIGAHMN-------V 486
Query: 845 AKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAA------SICIQFAE 898
+ YK+ LN+ + + + L P++IP +K A ++ I A
Sbjct: 487 GRTYKN---------LNRTKEAEESYMMAKSL-MPQIIPGKKYAARIAPNHLNVYINLAN 536
Query: 899 HYLA-EKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNH 957
A E ++A Q Y+ S P + + +L L ++ L+ ++N+
Sbjct: 537 LIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNN 596
Query: 958 ETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFEL 1017
+A + ++ A+ +++ LE P + L L +++ SG+++ P +
Sbjct: 597 ADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKR 656
Query: 1018 AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHM 1069
+ PL+ + G+ + NEA ++ KA K +SA++++
Sbjct: 657 LLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNL 708
Score = 34.7 bits (78), Expect = 0.62
Identities = 71/355 (20%), Positives = 132/355 (37%), Gaps = 41/355 (11%)
Query: 298 HLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWY 357
HL I ++ L +++ L + P + G L + N+ +A Y
Sbjct: 527 HLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAY 586
Query: 358 SEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSR 417
+A++LD++ + + HI L+E L+ + K ++ +F A++M
Sbjct: 587 LKALELDRNNADLWYNLAIVHI---ELKEPNEALKNFNRALELNPKHKLALFNSAIVMQ- 642
Query: 418 KHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAK---EYLLFCPKQPR 474
E L EA + S + PL + + L L K E ++ K +
Sbjct: 643 ----ESGEVKLRPEARKRLLSYINEEPLDANGYFNLG--MLAMDDKKDNEAEIWMKKAIK 696
Query: 475 LPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELEN-------------- 520
L S L +A++ + K AL P+ L +RYY ++
Sbjct: 697 LQADFRSALFN-LALLYSQTAKELKAL--PI-LEELLRYYPDHIKGLILKGDILMNQKKD 752
Query: 521 ---AQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHL 577
A+ +R LE+DP++V +C +Y + + CL + H Y
Sbjct: 753 ILGAKKCFERILEMDPSNVQGKHNLCVVYFEEKDLLKAERCL----LETLALAPHEEY-- 806
Query: 578 IKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVE 632
R LN D + ++ + + EG+K SV+ + S ++V+
Sbjct: 807 -IQRHLNIVRDKISSSSFIEPIFPTSKISSVEGKKIPTESVKEIRGESRQTQIVK 860
>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
Length = 858
Score = 37.4 bits (85), Expect = 0.096
Identities = 68/302 (22%), Positives = 116/302 (38%), Gaps = 33/302 (10%)
Query: 732 SLLLGDALMSILEPE---KALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEA 788
SL DA + + E KAL+ + A + P D + + Q + A+E +
Sbjct: 498 SLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQE 557
Query: 789 AQKINGQDFLCCDLGKLLLKLKKVNK-AEKVLKQAL-EHDIVQDIPSMMNDVKC------ 840
A K+ D L LL +K ++ A V+ A+ EH ++ M VK
Sbjct: 558 ALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHP--ENFNLMFTKVKLEQVLKG 615
Query: 841 ----------LLLLAKVYKSHKKEAVIE---TLNKALDLQSRILKRVPLEQPEMIPSQKQ 887
+L L + S + +E + + L ++ + + L S +
Sbjct: 616 PEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSR 675
Query: 888 LAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD---LCE 944
A+SI E ++E +V + T ++ L+ A+L++ Q HL C
Sbjct: 676 RASSIAASRLEEAMSELTMPSSVLK-QGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCI 734
Query: 945 QHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRR 1004
Q A L T + +A++ K E A LY + L PD ++H L +L R
Sbjct: 735 QEAAGLFPTSHSVLYMRGRLAEV---KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 791
Query: 1005 SG 1006
G
Sbjct: 792 LG 793
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 36.6 bits (83), Expect = 0.16
Identities = 69/285 (24%), Positives = 107/285 (37%), Gaps = 45/285 (15%)
Query: 744 EPEKALEVYDEAYRQNPHDASLASRIGHAYVK---AHQYTEAIEYYEAAQKINGQDFLCC 800
EPE EV + + H + + Y K H EA++ + A + G+D
Sbjct: 1359 EPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQK 1418
Query: 801 DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETL 860
D L K K + +K L+ E D + + + K L K +K+ +E
Sbjct: 1419 DTA-LEQKDKALEPKDKDLE---EKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPK 1474
Query: 861 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAE-----------KEYDKA 909
+K L+ + R+L EQ E IP +K A ++ EH E ++ DKA
Sbjct: 1475 DKDLEQKDRVL-----EQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKA 1529
Query: 910 ------VQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD-LCEQHCAILLQTEQNHETASV 962
Q KD S K L Q Y G D EQ+ L + Q E S+
Sbjct: 1530 PEQKHQAQEQKDKVS-----EKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESL 1584
Query: 963 LMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGK 1007
+ D RK K + EK+P+ + + ++ L K
Sbjct: 1585 VQED-KTRKPK---------MLEEKSPEKVKAMEEKLEALLEKTK 1619
>gi|17149828 NMDA receptor regulated 1 [Homo sapiens]
Length = 866
Score = 36.6 bits (83), Expect = 0.16
Identities = 52/240 (21%), Positives = 95/240 (39%), Gaps = 19/240 (7%)
Query: 707 QTLRDRRLYIRCYRELCEHLPGPHTSLLL----GDALMSILEPEKALEVYDEAYRQNPHD 762
Q LR+ LY LC + L + G+ L+ + E A +VY +NP +
Sbjct: 198 QVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPEN 257
Query: 763 ASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQA 822
+ + A +K E ++ YE A + + +L L K ++ L +
Sbjct: 258 WAYYKGLEKA-LKPANMLERLKIYEEAWTKYPRGLV---PRRLPLNFLSGEKFKECLDKF 313
Query: 823 LEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMI 882
L + + P + N ++ L YK +K A+IE L + LK L P
Sbjct: 314 LRMNFSKGCPPVFNTLRSL------YKDKEKVAIIEELVVGYETS---LKSCRLFNPNDD 364
Query: 883 PSQKQLAASICIQF--AEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHL 940
++ + +Q+ A+HY + A++ PT ++ L A++Y G++
Sbjct: 365 GKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNI 424
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 36.2 bits (82), Expect = 0.21
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)
Query: 882 IPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD 941
+ SQK L + Y + +YD+A+ Y P + + A Y
Sbjct: 128 VDSQKALVLK---EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
Query: 942 LCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 998
+ E C + + +++ A F QK E A Y +VLE P+NF ++L
Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNEL 241
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 36.2 bits (82), Expect = 0.21
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)
Query: 882 IPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD 941
+ SQK L + Y + +YD+A+ Y P + + A Y
Sbjct: 128 VDSQKALVLK---EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
Query: 942 LCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 998
+ E C + + +++ A F QK E A Y +VLE P+NF ++L
Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNEL 241
Score = 32.3 bits (72), Expect = 3.1
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 22/151 (14%)
Query: 164 KKAIEYLEQGIQ-DTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLK-- 220
++AIE +GI D + L +AM ++ Q Y EA + Q + GS+ A +
Sbjct: 299 ERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358
Query: 221 MQLFL-----ARQDWEQT--VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKT 273
+ FL A+QD+E +E G++ + S I EL +G+ V T
Sbjct: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK-------KELIEKGHWDDVFLDST 411
Query: 274 QKATNHVRNLIKALETREPENPSLHLKKIIV 304
Q+ +N++K ++ + LKK+I+
Sbjct: 412 QR-----QNVVKPIDNPPHPGSTKPLKKVII 437
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 36.2 bits (82), Expect = 0.21
Identities = 52/286 (18%), Positives = 107/286 (37%), Gaps = 60/286 (20%)
Query: 736 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 795
G+ + + + EKA E Y EA R + IG Y K ++ EA++ +
Sbjct: 500 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCF--------- 550
Query: 796 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEA 855
LKL + + N + L +A +Y+
Sbjct: 551 -----------LKLHAI---------------------LRNSAEVLYQIANIYE------ 572
Query: 856 VIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKD 915
++E ++A++ +++ +P + P+++ + E Y E + +A Q Y +
Sbjct: 573 LMENPSQAIEWLMQVVSVIPTD-PQVLS-----------KLGELYDREGDKSQAFQYYYE 620
Query: 916 VFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHE 975
+ Y P + +V+ L Y+ + Q+ + +++A R ++
Sbjct: 621 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQ 680
Query: 976 AAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1021
A++ Y K P+N L L+ L G L+D + K++
Sbjct: 681 KALDTYKDTHRKFPENVECLRFLVRLCTDLG-LKDAQEYARKLKRL 725
Score = 36.2 bits (82), Expect = 0.21
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 637 NGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN-VDVALNMLRNILPKQSCYM 695
NG+ +A + ++ + E + N+ L K N +D AL+ +
Sbjct: 506 NGDYEKAAEFYKEALRNDSSCTE----ALYNIGLTYEKLNRLDEALDCFLKLHAILRNSA 561
Query: 696 EAREKMANIYLQTLRDRRLYIRCYRELCEHLP-GPHTSLLLGDALMSILEPEKALEVYDE 754
E ++ANIY + + + I ++ +P P LG+ + +A + Y E
Sbjct: 562 EVLYQIANIY-ELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYE 620
Query: 755 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 792
+YR P + + +G Y+ + +AI+Y+E A I
Sbjct: 621 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLI 658
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 36.2 bits (82), Expect = 0.21
Identities = 52/286 (18%), Positives = 107/286 (37%), Gaps = 60/286 (20%)
Query: 736 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 795
G+ + + + EKA E Y EA R + IG Y K ++ EA++ +
Sbjct: 491 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCF--------- 541
Query: 796 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEA 855
LKL + + N + L +A +Y+
Sbjct: 542 -----------LKLHAI---------------------LRNSAEVLYQIANIYE------ 563
Query: 856 VIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKD 915
++E ++A++ +++ +P + P+++ + E Y E + +A Q Y +
Sbjct: 564 LMENPSQAIEWLMQVVSVIPTD-PQVLS-----------KLGELYDREGDKSQAFQYYYE 611
Query: 916 VFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHE 975
+ Y P + +V+ L Y+ + Q+ + +++A R ++
Sbjct: 612 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQ 671
Query: 976 AAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1021
A++ Y K P+N L L+ L G L+D + K++
Sbjct: 672 KALDTYKDTHRKFPENVECLRFLVRLCTDLG-LKDAQEYARKLKRL 716
Score = 36.2 bits (82), Expect = 0.21
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 637 NGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN-VDVALNMLRNILPKQSCYM 695
NG+ +A + ++ + E + N+ L K N +D AL+ +
Sbjct: 497 NGDYEKAAEFYKEALRNDSSCTE----ALYNIGLTYEKLNRLDEALDCFLKLHAILRNSA 552
Query: 696 EAREKMANIYLQTLRDRRLYIRCYRELCEHLP-GPHTSLLLGDALMSILEPEKALEVYDE 754
E ++ANIY + + + I ++ +P P LG+ + +A + Y E
Sbjct: 553 EVLYQIANIY-ELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYE 611
Query: 755 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 792
+YR P + + +G Y+ + +AI+Y+E A I
Sbjct: 612 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLI 649
>gi|15619013 43 kD receptor-associated protein of the synapse
isoform 1 [Homo sapiens]
Length = 412
Score = 35.0 bits (79), Expect = 0.48
Identities = 54/223 (24%), Positives = 92/223 (41%), Gaps = 48/223 (21%)
Query: 719 YRELCEHLPGPHT--------SLLLGDALMSILEPEKALEVYDEA--YRQNPHDASLASR 768
Y + C LPG SL +G+A + + +KALE +++A Y N DA L R
Sbjct: 105 YCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECR 164
Query: 769 I----GHAYVKAHQYTEAIEY-YEAAQKING------------QDFLCCDLGKLLLKL-K 810
+ G Y + Y +A+ + +AA+ +N + +LL +L
Sbjct: 165 VCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGS 224
Query: 811 KVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSH-KKEAVIETLNKALDLQSR 869
+ E+ +K AL+H D P CLL A +++S E + A+ + +
Sbjct: 225 AMECCEESMKIALQHG---DRPL---QALCLLCFADIHRSRGDLETAFPRYDSAMSIMTE 278
Query: 870 ILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQS 912
I R+ Q Q + A+ ++A K DKA+ +
Sbjct: 279 IGNRL---------GQVQALLGV----AKCWVARKALDKALDA 308
>gi|209976994 adenylate cyclase 10 [Homo sapiens]
Length = 1610
Score = 34.7 bits (78), Expect = 0.62
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 858 ETLNKALDLQSRILKRVPLEQPEMIPSQ----KQLAASICIQFAEHYLAEKEYDKAVQSY 913
E K L+ +L ++ ++IP + +++ + + A H+LA E DKA+ +
Sbjct: 1029 EIREKILNFFDHVLTKMKTSDEDIIPLESCQCEEILEIVILPLAHHFLALGENDKALYYF 1088
Query: 914 KDVFS-YLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQ 972
++ S YL + M A +YL +G LL+T + ++ S F
Sbjct: 1089 LEIASAYLIFCDNYM---AYMYLNEGQK---------LLKTLKKDKSWSQTFESATFYSL 1136
Query: 973 KHEAAINLYHQVLEKAPDNFLVLHKLIDLLRR 1004
K E N+ VL K +L K + LL R
Sbjct: 1137 KGEVCFNMGQIVLAKK-----MLRKALKLLNR 1163
>gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens]
Length = 843
Score = 34.7 bits (78), Expect = 0.62
Identities = 21/94 (22%), Positives = 45/94 (47%)
Query: 908 KAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADL 967
KA+ +++ S PTD++ LA + + + LQ + + + L+A L
Sbjct: 499 KALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALL 558
Query: 968 MFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDL 1001
+ ++ + A+N+ L + P+NF++L + L
Sbjct: 559 LSAQKHYHDALNIIDMALSEYPENFILLFSKVKL 592
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 33.9 bits (76), Expect = 1.1
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 43/204 (21%)
Query: 1110 EKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEAALGSFIQIAQAEKDSVPALLALA 1169
E L +Y Q +LR G E N++ G I + EK +++ L
Sbjct: 171 EVALEGYYKDKLFDQRELRFEIG-------EGENLDLPYGLERAIQRMEKGE-HSIVYLK 222
Query: 1170 QAYVFLK------QIP-----KARMQLKRL--AKTPWVLSEAEDLEKSWLLL--ADIYCQ 1214
+Y F QIP K + LK AK W ++ E LE+S ++ +Y +
Sbjct: 223 PSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFK 282
Query: 1215 GSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIG 1274
K+ AL ++ V + +E E S+ + A + + H N
Sbjct: 283 EGKYKQALLQYKKIVSW--------------LEYESSFSNEEAQKAQALRLASHLN---- 324
Query: 1275 FKLAFNYLKDKKFVEAIEICNDVL 1298
LA +LK + F AIE CN L
Sbjct: 325 --LAMCHLKLQAFSAAIESCNKAL 346
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 773 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 823
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 824 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 878
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 879 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 938
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 939 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 990
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 991 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1050
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1051 FLNKARKDST 1060
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 773 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 823
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 824 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 878
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 879 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 938
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 939 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 990
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 991 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1050
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1051 FLNKARKDST 1060
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 773 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 823
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 824 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 878
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 879 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 938
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 939 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 990
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 991 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1050
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1051 FLNKARKDST 1060
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,190,327
Number of Sequences: 37866
Number of extensions: 1989244
Number of successful extensions: 6165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 5879
Number of HSP's gapped (non-prelim): 284
length of query: 1321
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1207
effective length of database: 13,930,794
effective search space: 16814468358
effective search space used: 16814468358
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.