BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156766084 transmembrane protein 16C [Homo sapiens] (981 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156766084 transmembrane protein 16C [Homo sapiens] 2028 0.0 gi|218084958 anoctamin 4 [Homo sapiens] 1235 0.0 gi|218156303 anoctamin 6 isoform b [Homo sapiens] 695 0.0 gi|218156299 anoctamin 6 isoform a [Homo sapiens] 695 0.0 gi|47106048 anoctamin 5 isoform a [Homo sapiens] 693 0.0 gi|218081589 anoctamin 5 isoform b [Homo sapiens] 692 0.0 gi|218156307 anoctamin 6 isoform c [Homo sapiens] 654 0.0 gi|218156305 anoctamin 6 isoform c [Homo sapiens] 654 0.0 gi|209862785 anoctamin 2 [Homo sapiens] 649 0.0 gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 639 0.0 gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 562 e-160 gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 525 e-149 gi|94536803 transmembrane protein 16K [Homo sapiens] 178 2e-44 gi|55741655 anoctamin 8 [Homo sapiens] 107 4e-23 gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 87 6e-17 gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 84 6e-16 gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 69 2e-11 gi|91982772 mucin 17 [Homo sapiens] 34 0.59 gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens] 34 0.77 gi|5729862 stem-loop (histone) binding protein [Homo sapiens] 32 3.8 gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo sapi... 31 5.0 gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapi... 31 5.0 gi|7706704 G protein-coupled receptor 89B [Homo sapiens] 31 5.0 gi|148234741 G protein-coupled receptor 89C [Homo sapiens] 31 5.0 gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens] 31 6.5 gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] 31 6.5 gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 30 8.5 gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 30 8.5 >gi|156766084 transmembrane protein 16C [Homo sapiens] Length = 981 Score = 2028 bits (5253), Expect = 0.0 Identities = 981/981 (100%), Positives = 981/981 (100%) Query: 1 MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST 60 MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST Sbjct: 1 MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST 60 Query: 61 ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT 120 ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT Sbjct: 61 ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT 120 Query: 121 YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR 180 YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR Sbjct: 121 YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR 180 Query: 181 NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR 240 NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR Sbjct: 181 NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR 240 Query: 241 SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF 300 SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF Sbjct: 241 SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF 300 Query: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN Sbjct: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360 Query: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG Sbjct: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420 Query: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA Sbjct: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480 Query: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS Sbjct: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540 Query: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV Sbjct: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600 Query: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL Sbjct: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660 Query: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW Sbjct: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720 Query: 721 SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL 780 SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL Sbjct: 721 SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL 780 Query: 781 LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR 840 LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR Sbjct: 781 LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR 840 Query: 841 FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY 900 FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY Sbjct: 841 FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY 900 Query: 901 EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA 960 EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA Sbjct: 901 EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA 960 Query: 961 ELEHLQQQRRKSGQPVHHEWP 981 ELEHLQQQRRKSGQPVHHEWP Sbjct: 961 ELEHLQQQRRKSGQPVHHEWP 981 >gi|218084958 anoctamin 4 [Homo sapiens] Length = 920 Score = 1235 bits (3195), Expect = 0.0 Identities = 580/849 (68%), Positives = 692/849 (81%), Gaps = 19/849 (2%) Query: 152 SSGPLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIH 211 S+G F+DGK RIDYILVYRK+N Q +KR FE+N+RAEGL +EKE ++ + DI+F+K+H Sbjct: 72 SNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLH 131 Query: 212 IPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFP 271 PW+ L +YAE++N+RMPFR+K YY R K M R+ R + W+ + PM LDK P Sbjct: 132 APWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLP 191 Query: 272 DLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLI 331 DLEE+DCYT PFS+ RIHHFII+NK+TFF+NATRSRIV+H+L+R KYE G +K+G+ +L+ Sbjct: 192 DLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLL 251 Query: 332 NNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEK 391 NGSY AAFP HEG+Y+S I+THG +N+RHLLYE WA WG+WYK+QPLDL+R YFGEK Sbjct: 252 TNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEK 311 Query: 392 IGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSL 451 IGLYFAWLGWYTGML PAA +GL VF YG+ T+++SQVS+E+C+AT++ MCP+CDK C Sbjct: 312 IGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPF 371 Query: 452 QRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEE 511 RL+DSC+YAKVT+LFDNG TVFFA+FMA+WATVFLEFWKRRR+++ Y WDLI+WEEEEE Sbjct: 372 MRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEE 431 Query: 512 TLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVY 571 +RPQFEAKY K E +NPI+GKPEP+Q +DK +RL+VS SGIFFMI +VI AVFG+V+Y Sbjct: 432 EIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIY 491 Query: 572 RLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTES 631 R+V + FA+FKW I+ Q AT+ AVCINF IIMLLN+ YEK+A LLTNLE PRTES Sbjct: 492 RVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTES 551 Query: 632 EWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDL 691 EWENSF LKMFLFQFVNLNSS FYIAFFLGRF GHPG Y +L +RWRLEECHPSGCLIDL Sbjct: 552 EWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDL 611 Query: 692 CLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKR---GIHDASIPQWENDWNLQPMNL 748 C+QMG+IM LKQ WNNFMELGYPLIQNWW+R K+++ S PQWE D+NLQPMN Sbjct: 612 CMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNA 671 Query: 749 HGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATD 808 +GL DEYLEM+LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPL +RA D Sbjct: 672 YGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKD 731 Query: 809 IGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNS 868 IGIW GILEGIGIL+VITNAFVIAITSD+IPR VY YKYGPCA E + C+ GYVN S Sbjct: 732 IGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNAS 791 Query: 869 LSFFDLSEL---------GMGKSG----YCRYRDYRGPPWSSKPYEFTLQYWHILAARLA 915 LS F +S+ G SG YCRYRDYR PP S PY +TLQ+WH+LAARLA Sbjct: 792 LSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLA 851 Query: 916 FIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ---QQRRKS 972 FIIVFEHLVF IK I+YLIPD+PK L DR+RREKYL+QEMMYEAELE LQ ++R+K+ Sbjct: 852 FIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKN 911 Query: 973 GQPVHHEWP 981 G+ H+EWP Sbjct: 912 GKAHHNEWP 920 >gi|218156303 anoctamin 6 isoform b [Homo sapiens] Length = 892 Score = 695 bits (1794), Expect = 0.0 Identities = 377/855 (44%), Positives = 536/855 (62%), Gaps = 63/855 (7%) Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205 F DG++RID++LVY ++TN Q KR +E NL GL LE ++ + Sbjct: 44 FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 103 Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265 +F+K+H PW+ LC YAE ++I++P + RS + G + NW + V Sbjct: 104 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 153 Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323 + P E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+ N +S Sbjct: 154 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 210 Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383 K GI +L+N+G Y AAFP H+ ++ + N R+LLY WA YK QPLDL Sbjct: 211 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 268 Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440 IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+ F YG +N S+E+C ++ Sbjct: 269 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 328 Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500 MCP CD+ C +LN +C +K +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y Sbjct: 329 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 388 Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559 WD +E ++EE+ RP++EA+ + ++N IT + E ++ K R+ + S +FF I Sbjct: 389 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 446 Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611 L+I +V G++VYRL V F A N I++Y Q ATS A I+FIIIM+LN Sbjct: 447 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 506 Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671 YEK+A ++TN E PRT++++ENS +KMFLFQFVN SS FYIAFF G+FVG+PG Sbjct: 507 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 566 Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730 ++R EEC P GCL++L Q+ +IM K IWNN E+ P I N R H++ Sbjct: 567 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 624 Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790 + P+WE D++LQPM GL EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D Sbjct: 625 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 684 Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848 A+K TQ+RR +P +A DIG W I++GI ILAV+TNA +IA TSD IPR VY + + Sbjct: 685 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 744 Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898 P +H + ++GY+NN+LS F +++ +G CRYRD+R PP + Sbjct: 745 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 801 Query: 899 PYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMY 958 Y+ + YWH++AA+LAFIIV EH+++ +K FI+Y IPDV K +I+REKYL Q++++ Sbjct: 802 EYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLH 861 Query: 959 EAELEHLQQQRRKSG 973 E HL+ + G Sbjct: 862 E---NHLKDMTKNMG 873 >gi|218156299 anoctamin 6 isoform a [Homo sapiens] Length = 910 Score = 695 bits (1794), Expect = 0.0 Identities = 377/855 (44%), Positives = 536/855 (62%), Gaps = 63/855 (7%) Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205 F DG++RID++LVY ++TN Q KR +E NL GL LE ++ + Sbjct: 62 FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121 Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265 +F+K+H PW+ LC YAE ++I++P + RS + G + NW + V Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171 Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323 + P E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+ N +S Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228 Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383 K GI +L+N+G Y AAFP H+ ++ + N R+LLY WA YK QPLDL Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286 Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440 IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+ F YG +N S+E+C ++ Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346 Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500 MCP CD+ C +LN +C +K +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406 Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559 WD +E ++EE+ RP++EA+ + ++N IT + E ++ K R+ + S +FF I Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464 Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611 L+I +V G++VYRL V F A N I++Y Q ATS A I+FIIIM+LN Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524 Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671 YEK+A ++TN E PRT++++ENS +KMFLFQFVN SS FYIAFF G+FVG+PG Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584 Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730 ++R EEC P GCL++L Q+ +IM K IWNN E+ P I N R H++ Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642 Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790 + P+WE D++LQPM GL EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702 Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848 A+K TQ+RR +P +A DIG W I++GI ILAV+TNA +IA TSD IPR VY + + Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762 Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898 P +H + ++GY+NN+LS F +++ +G CRYRD+R PP + Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819 Query: 899 PYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMY 958 Y+ + YWH++AA+LAFIIV EH+++ +K FI+Y IPDV K +I+REKYL Q++++ Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLH 879 Query: 959 EAELEHLQQQRRKSG 973 E HL+ + G Sbjct: 880 E---NHLKDMTKNMG 891 >gi|47106048 anoctamin 5 isoform a [Homo sapiens] Length = 913 Score = 693 bits (1788), Expect = 0.0 Identities = 388/897 (43%), Positives = 549/897 (61%), Gaps = 62/897 (6%) Query: 106 LGKDKDYT---DESEHATYDRSRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKD 159 + K DY+ E ++ + S LIN+ + K F L + M N + F+D Sbjct: 17 VNKHIDYSFQMSEQSLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRD 75 Query: 160 GKKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHI 212 G ++ID++L Y + ++ ++R FE NLR GL LE E S D F+KIH Sbjct: 76 GIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHA 135 Query: 213 PWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPD 272 PW+ L YAE L I+MP ++ + P+ L S Sbjct: 136 PWEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSV--K 180 Query: 273 LEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKL 330 + +T FSR R F+I ++ TFF +++R+RIVY++L R + E+G + GI +L Sbjct: 181 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 240 Query: 331 INNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFG 389 +N+ +Y +A+P H+G Y K S+P P N R+ L++ WAR+ +YK QPLDLI+ Y+G Sbjct: 241 LNSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 297 Query: 390 EKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCD 446 EKIG+YF +LG+YT ML AA+VGL F YGL +M ++ S EIC ++ MCPLCD Sbjct: 298 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 357 Query: 447 KNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEW 506 + C RLN +C+ +K ++LFDN TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++ Sbjct: 358 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 417 Query: 507 EEEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITA 564 EEE++ L RP+FEA K +N +T + EP+ P ++ +S + + +SLV+T+ Sbjct: 418 EEEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTS 476 Query: 565 VFGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKI 617 + V+VYRL V FASF + +KQ F TS C+NFI+I++LN YEKI Sbjct: 477 MVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKI 536 Query: 618 AYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRW 677 + +T +E PRT E+E+S LKMFLFQFVN SS FY+AFF G+FVG+PGKY LF+ W Sbjct: 537 SAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEW 596 Query: 678 RLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQW 737 R EEC P GCLI+L Q+ +IM KQI+ N E YPL NWW R K + + +W Sbjct: 597 RSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRW 655 Query: 738 ENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 797 E D +L+ GL EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ Sbjct: 656 EQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQ 715 Query: 798 WRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPS 857 +RR + ++A IG+W IL G+ +L+V TNAF++A TSD IPR VY Y Y N +P Sbjct: 716 YRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP- 772 Query: 858 ENCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHIL 910 + GYVNNSLS F +++ + CRYRDYR PP Y +Q+WH+L Sbjct: 773 ---MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVL 829 Query: 911 AARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967 AA++ FIIV EH+VF +K +A++IPDVPK + +RI+REK + +++++ EL L++ Sbjct: 830 AAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 886 >gi|218081589 anoctamin 5 isoform b [Homo sapiens] Length = 912 Score = 692 bits (1787), Expect = 0.0 Identities = 388/896 (43%), Positives = 548/896 (61%), Gaps = 61/896 (6%) Query: 106 LGKDKDYTDESEHATYDR--SRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKDG 160 + K DY+ + + R S LIN+ + K F L + M N + F+DG Sbjct: 17 VNKHIDYSFQMSESLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRDG 75 Query: 161 KKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHIP 213 ++ID++L Y + ++ ++R FE NLR GL LE E S D F+KIH P Sbjct: 76 IRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAP 135 Query: 214 WDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDL 273 W+ L YAE L I+MP ++ + P+ L S Sbjct: 136 WEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSV--KY 180 Query: 274 EESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKLI 331 + +T FSR R F+I ++ TFF +++R+RIVY++L R + E+G + GI +L+ Sbjct: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240 Query: 332 NNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGE 390 N+ +Y +A+P H+G Y K S+P P N R+ L++ WAR+ +YK QPLDLI+ Y+GE Sbjct: 241 NSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGE 297 Query: 391 KIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCDK 447 KIG+YF +LG+YT ML AA+VGL F YGL +M ++ S EIC ++ MCPLCD+ Sbjct: 298 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 357 Query: 448 NCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWE 507 C RLN +C+ +K ++LFDN TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++E Sbjct: 358 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 417 Query: 508 EEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAV 565 EE++ L RP+FEA K +N +T + EP+ P ++ +S + + +SLV+T++ Sbjct: 418 EEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSM 476 Query: 566 FGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKIA 618 V+VYRL V FASF + +KQ F TS C+NFI+I++LN YEKI+ Sbjct: 477 VAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKIS 536 Query: 619 YLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWR 678 +T +E PRT E+E+S LKMFLFQFVN SS FY+AFF G+FVG+PGKY LF+ WR Sbjct: 537 AWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWR 596 Query: 679 LEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQWE 738 EEC P GCLI+L Q+ +IM KQI+ N E YPL NWW R K + + +WE Sbjct: 597 SEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRWE 655 Query: 739 NDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQW 798 D +L+ GL EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ+ Sbjct: 656 QDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQY 715 Query: 799 RRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE 858 RR + ++A IG+W IL G+ +L+V TNAF++A TSD IPR VY Y Y N +P Sbjct: 716 RRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP-- 771 Query: 859 NCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHILA 911 + GYVNNSLS F +++ + CRYRDYR PP Y +Q+WH+LA Sbjct: 772 --MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLA 829 Query: 912 ARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967 A++ FIIV EH+VF +K +A++IPDVPK + +RI+REK + +++++ EL L++ Sbjct: 830 AKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 885 >gi|218156307 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 654 bits (1686), Expect = 0.0 Identities = 357/805 (44%), Positives = 504/805 (62%), Gaps = 60/805 (7%) Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205 F DG++RID++LVY ++TN Q KR +E NL GL LE ++ + Sbjct: 62 FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121 Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265 +F+K+H PW+ LC YAE ++I++P + RS + G + NW + V Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171 Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323 + P E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+ N +S Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228 Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383 K GI +L+N+G Y AAFP H+ ++ + N R+LLY WA YK QPLDL Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286 Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440 IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+ F YG +N S+E+C ++ Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346 Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500 MCP CD+ C +LN +C +K +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406 Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559 WD +E ++EE+ RP++EA+ + ++N IT + E ++ K R+ + S +FF I Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464 Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611 L+I +V G++VYRL V F A N I++Y Q ATS A I+FIIIM+LN Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524 Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671 YEK+A ++TN E PRT++++ENS +KMFLFQFVN SS FYIAFF G+FVG+PG Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584 Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730 ++R EEC P GCL++L Q+ +IM K IWNN E+ P I N R H++ Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642 Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790 + P+WE D++LQPM GL EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702 Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848 A+K TQ+RR +P +A DIG W I++GI ILAV+TNA +IA TSD IPR VY + + Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762 Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898 P +H + ++GY+NN+LS F +++ +G CRYRD+R PP + Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819 Query: 899 PYEFTLQYWHILAARLAFIIVFEHL 923 Y+ + YWH++AA+LAFIIV E+L Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEYL 844 >gi|218156305 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 654 bits (1686), Expect = 0.0 Identities = 357/805 (44%), Positives = 504/805 (62%), Gaps = 60/805 (7%) Query: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205 F DG++RID++LVY ++TN Q KR +E NL GL LE ++ + Sbjct: 62 FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 121 Query: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265 +F+K+H PW+ LC YAE ++I++P + RS + G + NW + V Sbjct: 122 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 171 Query: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323 + P E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+ N +S Sbjct: 172 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 228 Query: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383 K GI +L+N+G Y AAFP H+ ++ + N R+LLY WA YK QPLDL Sbjct: 229 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 286 Query: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440 IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+ F YG +N S+E+C ++ Sbjct: 287 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 346 Query: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500 MCP CD+ C +LN +C +K +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y Sbjct: 347 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 406 Query: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559 WD +E ++EE+ RP++EA+ + ++N IT + E ++ K R+ + S +FF I Sbjct: 407 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 464 Query: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611 L+I +V G++VYRL V F A N I++Y Q ATS A I+FIIIM+LN Sbjct: 465 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 524 Query: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671 YEK+A ++TN E PRT++++ENS +KMFLFQFVN SS FYIAFF G+FVG+PG Sbjct: 525 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 584 Query: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730 ++R EEC P GCL++L Q+ +IM K IWNN E+ P I N R H++ Sbjct: 585 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 642 Query: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790 + P+WE D++LQPM GL EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D Sbjct: 643 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 702 Query: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848 A+K TQ+RR +P +A DIG W I++GI ILAV+TNA +IA TSD IPR VY + + Sbjct: 703 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 762 Query: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898 P +H + ++GY+NN+LS F +++ +G CRYRD+R PP + Sbjct: 763 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 819 Query: 899 PYEFTLQYWHILAARLAFIIVFEHL 923 Y+ + YWH++AA+LAFIIV E+L Sbjct: 820 EYKHNIYYWHVIAAKLAFIIVMEYL 844 >gi|209862785 anoctamin 2 [Homo sapiens] Length = 998 Score = 649 bits (1674), Expect = 0.0 Identities = 356/826 (43%), Positives = 499/826 (60%), Gaps = 61/826 (7%) Query: 178 DKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYT 237 ++R FE NL GL LEK+ S +F++IH PW L + AE L I++P KK Y Sbjct: 153 EQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVP-TKKMYEI 211 Query: 238 DGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKD 297 + +++ + + P V + S + + PFSR +++ + I KD Sbjct: 212 KAGGSIAKKFSAALQKLSSHL--QPRVPEHSN----NKMKNLSYPFSREKMYLYNIQEKD 265 Query: 298 TFFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHG 357 TFF NATRSRIV+ +L+RT + +GI LI N Y AA+P H+G Y S + Sbjct: 266 TFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPED----- 320 Query: 358 PQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVF 417 N+R LLY+ WAR+G++YK QP+DLIR YFGEKIGLYFAWLG YT LIP++++G+ VF Sbjct: 321 DMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF 380 Query: 418 FYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFA 476 YG T+ S+E+C F MCPLCDK+C L+ +C A+ ++LFDN TVFF+ Sbjct: 381 LYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFS 440 Query: 477 IFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEAKY----------- 521 IFMA+WAT+FLE WKR + L Y WDL EEEEE RP++E K Sbjct: 441 IFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQS 500 Query: 522 --YKMEIVNPITGKPEPHQPSS--DKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVME 577 K+E G + + D+ L++ + I FMI+L + VFGV+VYR+ Sbjct: 501 AVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAA 560 Query: 578 QFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSF 637 + K + + +A AV IN ++I++L+ Y +A LT +E P+TE +E Sbjct: 561 ALSLNKAT--RSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERL 618 Query: 638 ALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGV 697 LK FL +FVN S IFY+AFF GRFVG PG Y +FD +R+EEC P GCL++LC+Q+ + Sbjct: 619 ILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSI 678 Query: 698 IMFLKQ-IWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHG 750 IM KQ I NN E+G P ++ + + K + H QW+ D++L+P G Sbjct: 679 IMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYT--G 736 Query: 751 LMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIG 810 L EY+EM++QFGF T+FVA+FPLAP+ ALLNN+IE+RLDA KFVT+ RRP R DIG Sbjct: 737 LTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIG 796 Query: 811 IWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLS 870 IW IL GIG +VI+NAFVIAITSD+IPR VY+Y Y L G+VN++LS Sbjct: 797 IWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS--------HNGTLHGFVNHTLS 848 Query: 871 FFDLSELGMG----------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVF 920 FF++S+L G + +CR++DYR PPW+ PYEF+ QYW IL+ARLAF+I+F Sbjct: 849 FFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIF 908 Query: 921 EHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ 966 ++LV + + ++IPD+P + D+I++EK L+ + + E E L+ Sbjct: 909 QNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 >gi|194306539 anoctamin 1, calcium activated chloride channel [Homo sapiens] Length = 986 Score = 639 bits (1647), Expect = 0.0 Identities = 358/858 (41%), Positives = 511/858 (59%), Gaps = 80/858 (9%) Query: 179 KRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTD 238 +R +E NL GL LE++ + F+KIH PW+ LC+ AE L ++MP KK Y+ + Sbjct: 127 RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMP-TKKMYHIN 185 Query: 239 GRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDT 298 + ++ + ++I + + P V + P + Y PFSR + H F +++KD+ Sbjct: 186 ETRGLLKKINSVLQKITDPI--QPKVAEHR--PQTMKRLSY--PFSREKQHLFDLSDKDS 239 Query: 299 FFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGP 358 FF + TRS IVY +L+RT +GI L+ NG Y AA+P H+G Y Sbjct: 240 FFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENV-----E 294 Query: 359 QNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFF 418 N+R LLYE WAR+G++YK+QP+DL+R YFGEKIGLYFAWLG YT MLIPA+IVG+ VF Sbjct: 295 FNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFL 354 Query: 419 YGLFTMNNSQVSQEIC-KATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAI 477 YG TM+ + S E+C + + MCPLCDK CS +++ +C A+ ++LFDN TVFF++ Sbjct: 355 YGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSV 414 Query: 478 FMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEA----KYYKMEIVNP 529 FMA+WA F+E WKR++ L Y WDL +EEEEE + R ++EA K K E N Sbjct: 415 FMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNK 474 Query: 530 ITGKPEPHQPSS------------------------DKVTRLLVSVSGIFFMISLVITAV 565 + P + ++ D+ L ++ I FMI++ V Sbjct: 475 EKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIV 534 Query: 566 FGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLE 625 GV++YR+ + A ++ + +A AV IN ++I+LL+ Y IA LT +E Sbjct: 535 LGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIE 594 Query: 626 YPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPS 685 P+TE +E K FL +FVN + IFY+AFF GRFVG PG Y +F +R+EEC P Sbjct: 595 VPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPG 654 Query: 686 GCLIDLCLQMGVIMFLKQ-IWNNFMELGYPLIQNWWSRHKIKRGI---HDASIPQ---WE 738 GCL++LC+Q+ +IM KQ I NN E+G P ++ K+K+ H+ + + +E Sbjct: 655 GCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYE 714 Query: 739 NDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQW 798 D+NL+P GL EY+EM++QFGF T+FVA+FPLAPL ALLNNIIEIRLDA KFVT+ Sbjct: 715 VDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEL 772 Query: 799 RRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE 858 RRP+ RA DIGIW IL GIG LAVI NAFVI+ TSD+IPR VY Y Y Sbjct: 773 RRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYS--------KN 824 Query: 859 NCLKGYVNNSLSFFDLSELGMGKS-------GY----CRYRDYRGPPWSSKPYEFTLQYW 907 + G+VN++LS F++S+ G + GY CRY+DYR PPWS Y+ + +W Sbjct: 825 GTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFW 884 Query: 908 HILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEH--- 964 +LAARLAF+IVF++LV + F+ ++IPD+PK + +I +EK L+ E+ E + Sbjct: 885 AVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQL 944 Query: 965 ----LQQQRRKSGQPVHH 978 ++++R+K P +H Sbjct: 945 LETWMEKERQKDEPPCNH 962 >gi|145207958 transmembrane protein 16G isoform NGEP long [Homo sapiens] Length = 933 Score = 562 bits (1449), Expect = e-160 Identities = 318/806 (39%), Positives = 477/806 (59%), Gaps = 54/806 (6%) Query: 172 KTNIQYDKRNTFEKNLRAEGLMLEKEPAI-ASPDIMFIKIHIPWDTLCKYAERLNIRMPF 230 +T++ R TF NLRA GL ++++ + + + + W LC YAE L +++P Sbjct: 133 RTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPL 192 Query: 231 RKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHH 290 ++ + + + W+ ++L+ PD+ + Y+ F ++ Sbjct: 193 QEL----------PNQASNWSAGLLAWLGIPNVLLE--VVPDVPP-EYYSCRFRVNKLPR 239 Query: 291 FI-INNKDTFFSNATRSRIVYHMLERTKYENGISKV-GIRKLINNGSYIAAFPPHEGAYK 348 F+ +N+DTFF++ R +I++ +L +T Y + + GI +L+ G AAFP H+G +K Sbjct: 240 FLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK 299 Query: 349 SSQPIKTHGPQ----NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTG 404 + GPQ N R +L++ WARWG W K+QPLD +R YFGEK+ LYFAWLG+YTG Sbjct: 300 TPP----EGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTG 355 Query: 405 MLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKV 463 L+PAA+VG VF G F + + +QE+C + + F MCPLC +C L+ +C A+ Sbjct: 356 WLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQA 414 Query: 464 TYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYK 523 LFD+GGTVFF++FMA+WA + LE+WKR+ + L Y WD ++E+ EE RPQF A Sbjct: 415 GRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASA-P 473 Query: 524 MEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFK 583 M NPITG+ EP+ P + R+L I M+++V+ + +++YR +M S Sbjct: 474 MTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYR-AIMAIVVSRS 532 Query: 584 WNFIKQYWQFA-TSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMF 642 N + W S +N + I++L+ Y +A++LT E RT++++E++F LK+F Sbjct: 533 GNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVF 592 Query: 643 LFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLK 702 +FQFVN SS YIAFF GRFVG+PG Y+ LF R EEC GCLI+L ++ VIM K Sbjct: 593 IFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLIELAQELLVIMVGK 651 Query: 703 QIWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHGLMDEYL 756 Q+ NN E+ P ++ WW + +++ AS WE+D+ L P GL DEYL Sbjct: 652 QVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCE--GLFDEYL 709 Query: 757 EMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGIL 816 EMVLQFGF TIFVAA PLAPL ALLNN +EIRLDA KFV ++RRP+ RA DIGIW IL Sbjct: 710 EMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHIL 769 Query: 817 EGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSE 876 G+ LAVI+NAF++A +SD++PR Y + + L+G++N +L+ S Sbjct: 770 AGLTHLAVISNAFLLAFSSDFLPRAYYRW----------TRAHDLRGFLNFTLARAP-SS 818 Query: 877 LGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIP 936 + CRYR +R ++ YW++LA RLAF+IVFEH+VF + + L+P Sbjct: 819 FAAAHNRTCRYRAFR-----DDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873 Query: 937 DVPKGLHDRIRREKYLVQEMMYEAEL 962 D+P+ + +++RE YL ++ + E E+ Sbjct: 874 DIPESVEIKVKREYYLAKQALAENEV 899 >gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] Length = 782 Score = 525 bits (1353), Expect = e-149 Identities = 284/666 (42%), Positives = 396/666 (59%), Gaps = 55/666 (8%) Query: 301 SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN 360 + + R RIV ++ K G + L+ +G + A FP H+G + Sbjct: 115 TTSLRIRIVNFVVMNNKTSAGET---FEDLMKDGVFEARFPLHKGEGR------------ 159 Query: 361 NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG 420 L + WARW ++ QP+D IR YFGEK+ LYF WLGWYT ML+PAA+ GL VF G Sbjct: 160 ----LKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSG 215 Query: 421 LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA 480 SQ+S+EIC+A ++ MCPL D + QRL+++C +AK+T+LFDN GTV FAIFMA Sbjct: 216 FSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMA 275 Query: 481 IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS 540 +WATVFLE WKR+R+ + WDL W+EE+E + ++++N K P+Q S Sbjct: 276 LWATVFLEIWKRQRARVVLHWDLYVWDEEQEEM---------ALQLINCPDYKLRPYQHS 326 Query: 541 SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV 600 + T +LV MI L+I +VVYR++ F+S F+++ A Sbjct: 327 YLRSTVILVLT---LLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGA 383 Query: 601 CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL 660 ++++ I+++ +A L + E PRT SE E+ F ++ F QF SS+ YIAF L Sbjct: 384 LVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFIL 443 Query: 661 GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW 720 GR GHPGK +L W+LEECH SGC++DL +QM +IM LKQ +N +E P W Sbjct: 444 GRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVP-----W 498 Query: 721 SRHKIK--RGIHDASIPQ------WENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAF 772 HK + R +P+ W ++ L P+N L DE++EM++Q+GFTTIFVAAF Sbjct: 499 VTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAF 558 Query: 773 PLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIA 832 PLAPLLAL +N++EIRLDA K V RR +P +A DIG WL +LE IG+LAVI N VIA Sbjct: 559 PLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIA 618 Query: 833 ITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSEL-------GMGKSGYC 885 TS++IPR VY+Y+Y PC + +CLKGYVN+SLS F + G C Sbjct: 619 FTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLC 678 Query: 886 RYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDR 945 RYRDYR PP Y F+ Q+W +LA RLAF+I+FEH+ IK A+ +PD+P+ + ++ Sbjct: 679 RYRDYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNK 734 Query: 946 IRREKY 951 + KY Sbjct: 735 VLEVKY 740 >gi|94536803 transmembrane protein 16K [Homo sapiens] Length = 660 Score = 178 bits (452), Expect = 2e-44 Identities = 166/567 (29%), Positives = 247/567 (43%), Gaps = 128/567 (22%) Query: 294 NNKDTFFSNATRSRIVYHMLE--RTKYENGI----------SKVGIRKLINNGSYIAAFP 341 +N D F + A I+ H LE R K E I K +R+L+ +G I FP Sbjct: 113 DNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFP 172 Query: 342 PHEGAYKSSQPIKTHGPQNNRHLLYERW-ARWGMWYKHQPLDLIRLYFGEKIGLYFAWLG 400 H+ S+ +K L + W R+ + K+QP+D IR YFGE I LYF +L Sbjct: 173 LHD-----SEALKK---------LEDTWYTRFAL--KYQPIDSIRGYFGETIALYFGFLE 216 Query: 401 WYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIY 460 ++T LIP A++GL Y LF + Y Sbjct: 217 YFTFALIPMAVIGLP---YYLFVWED---------------------------------Y 240 Query: 461 AKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAK 520 K V FA F IW+TV LE WKR + +TY W + + + E RP F Sbjct: 241 DKY---------VIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGV 291 Query: 521 YYKMEIVNPITGKPEPHQPSSDKVTRL-LVSVSGI---FFMISLVITAVFGVVVYRLVVM 576 +N ITGK EP PS + R+ LVS+ + + V+ F + V+ L + Sbjct: 292 LG----INSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLH 347 Query: 577 EQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENS 636 E S +W + Y I I+I ++N Y A LT+ E R ES ++N Sbjct: 348 ENSGS-EWTSVLLY-------VPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNH 399 Query: 637 FALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMG 696 LK+ +F F+N +S+FYIAF L K KL L + Sbjct: 400 LILKVLVFNFLNCFASLFYIAFVL--------KDMKL-----------------LRQSLA 434 Query: 697 VIMFLKQIWNNFMELGYPLIQNWWSRHK----IKRGIH----DASIPQWENDWNLQPMNL 748 ++ QI N ME P +W + K +KR + D +E + M Sbjct: 435 TLLITSQILNQIMESFLP----YWLQRKHGVRVKRKVQALKADIDATLYEQVILEKEMGT 490 Query: 749 H-GLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARAT 807 + G D+YLE+ LQFG+ ++F +PLA A+LNN E+ DA K ++RP + Sbjct: 491 YLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSA 550 Query: 808 DIGIWLGILEGIGILAVITNAFVIAIT 834 +IG+W E + +++V+TN +I ++ Sbjct: 551 NIGVWQLAFETMSVISVVTNCALIGMS 577 Score = 32.7 bits (73), Expect = 1.7 Identities = 14/65 (21%), Positives = 37/65 (56%), Gaps = 4/65 (6%) Query: 914 LAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAEL----EHLQQQR 969 + ++ EH + +K +A+ IPD P+ + ++ R ++ E + + ++ E+L+++ Sbjct: 592 ILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEP 651 Query: 970 RKSGQ 974 +SG+ Sbjct: 652 MESGK 656 >gi|55741655 anoctamin 8 [Homo sapiens] Length = 1232 Score = 107 bits (268), Expect = 4e-23 Identities = 103/384 (26%), Positives = 164/384 (42%), Gaps = 85/384 (22%) Query: 291 FIINNKDT---FFSNATRSRIVYHMLERTKYENGISKVGIR---------KLINNGSYIA 338 FI N ++ FF++ R I+ L+ + + G + +R +L G Sbjct: 148 FIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQ 207 Query: 339 AFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAW 398 FP HE Q + L + W + ++QPLD I YFG KI +YFAW Sbjct: 208 VFPVHE--------------QRILNRLMKSWVQ--AVCENQPLDDICDYFGVKIAMYFAW 251 Query: 399 LGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSC 458 LG+YT ++ A+ G ++ + Q S+++ SC Sbjct: 252 LGFYTSAMVYPAVFGSVLYTF----TEADQTSRDV-----------------------SC 284 Query: 459 IYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWE-EEEETLRPQF 517 V FA+F IW+T+FLE WKRR + L Y W ++ E E RPQF Sbjct: 285 --------------VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQF 330 Query: 518 EAKYYKMEIVNPITGKPEPHQPSSDKVT-RLLVSVSGIFFMISLVITAVFGVVVYRLVVM 576 + ++PIT E + P ++ +LLVS+ + V + G + +V+ Sbjct: 331 RG----VRRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVL 386 Query: 577 EQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENS 636 +K + A V + ++ + Y+K+A L ++E R ES +E Sbjct: 387 S---------VKGLPRLARFLPKVMLALLVSVSAE-GYKKLAIWLNDMENYRLESAYEKH 436 Query: 637 FALKMFLFQFVNLNSSIFYIAFFL 660 +K+ LFQFVN S+FYI F+L Sbjct: 437 LIIKVVLFQFVNSYLSLFYIGFYL 460 Score = 83.2 bits (204), Expect = 1e-15 Identities = 37/78 (47%), Positives = 54/78 (69%) Query: 754 EYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWL 813 +Y EM +QFG+ +F +AFPLA L AL+NN+IEIR DA+K T +RP R IG W Sbjct: 747 DYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQ 806 Query: 814 GILEGIGILAVITNAFVI 831 ++E +G+LA++ N ++I Sbjct: 807 KVMEAMGVLAIVVNCYLI 824 Score = 33.9 bits (76), Expect = 0.77 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 907 WHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMM--YEAELEH 964 W A + ++V EH +K I IPD+P + + + + +Y +E +E + +H Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895 Query: 965 --LQQQRRK 971 QQQRR+ Sbjct: 896 RYQQQQRRR 904 >gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] Length = 719 Score = 87.4 bits (215), Expect = 6e-17 Identities = 122/522 (23%), Positives = 187/522 (35%), Gaps = 158/522 (30%) Query: 462 KVTYLFDNGGTVFFAIFMAIW-----------ATVFLEFW-------------------- 490 K++ LFD+ GTVFF+IFM+ W + W Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313 Query: 491 -------KRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDK 543 + S + WD +++++EE QF A +M NP+TG EP+ Sbjct: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMT-QNPVTGLKEPYFQPHSC 372 Query: 544 VTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCIN 603 ++ LL S + I ++ +V+ + V++Y ++ A F N Sbjct: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGII--SIAMFHTG-----------------N 413 Query: 604 FIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRF 663 +++ N+ W N M + +L+ S+ FF Sbjct: 414 SVLMTQANVL-------------------WGNGGDASM---KMPSLSFSVCQFLFF---- 447 Query: 664 VGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQNW 719 L +C P GC I + Q+ +IM KQ+ N+ E G P Sbjct: 448 --------SLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP----- 494 Query: 720 WSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLA 779 G +P+ LQFGF TIFV AF LAPL Sbjct: 495 --------GPDTPCLPE-----------------------LQFGFITIFVGAFLLAPLFT 523 Query: 780 LLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIP 839 LLNN +EI LDA+KF+ +++RP+ R G ++ TNA Sbjct: 524 LLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA----------- 572 Query: 840 RFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKP 899 + G N + + G + F + ++ RY+ R Sbjct: 573 ----RSRLGYWLN----GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DVG 619 Query: 900 YEFTLQYWHILA--ARLAFIIVFEHLVFGIKSFIAYLIPDVP 939 L YW +LA L FII FE++VF L+PDVP Sbjct: 620 VNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661 Score = 37.7 bits (86), Expect = 0.053 Identities = 14/23 (60%), Positives = 17/23 (73%) Query: 360 NNRHLLYERWARWGMWYKHQPLD 382 N+ LLY WA WG W+K+QPLD Sbjct: 227 NSCQLLYPYWACWGYWHKYQPLD 249 >gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] Length = 723 Score = 84.0 bits (206), Expect = 6e-16 Identities = 129/583 (22%), Positives = 200/583 (34%), Gaps = 187/583 (32%) Query: 401 WYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIY 460 +Y L+P +VG +F L T+ + + ++ Sbjct: 226 FYMACLLPVTLVGTLLFISSLVTVGTNTL-----------------------------VW 256 Query: 461 AKVTYLFDNGGTVFFAIFMAIW-----------ATVFLEFW------------------- 490 V L D GTVFF+IFM+ W + W Sbjct: 257 VAVEGLGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHW 316 Query: 491 --------KRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSD 542 + S + WD +++++EE QF A +M NP+TG EP+ Sbjct: 317 DCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMT-QNPVTGLKEPYFQPHS 375 Query: 543 KVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCI 602 ++ LL S + I ++ +V+ + V++Y ++ A F Sbjct: 376 CLSHLLTSSAAILTVLCVVMIFLVSVIIYHGII--SIAMFHTG----------------- 416 Query: 603 NFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGR 662 N +++ N+ W N M + +L+ S+ FF Sbjct: 417 NSVLMTQANVL-------------------WGNGGDASM---KMPSLSFSVCQFLFF--- 451 Query: 663 FVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQN 718 L +C P GC I + Q+ +IM KQ+ N+ E G P Sbjct: 452 ---------SLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP---- 498 Query: 719 WWSRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLL 778 G +P+ LQFGF TIFV AF LAPL Sbjct: 499 ---------GPDTPCLPE-----------------------LQFGFITIFVGAFLLAPLF 526 Query: 779 ALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYI 838 LLNN +EI LDA+KF+ +++RP+ R G ++ TNA Sbjct: 527 TLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA---------- 576 Query: 839 PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSK 898 + G N + + G + F + ++ RY+ R Sbjct: 577 -----RSRLGYWLN----GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DV 622 Query: 899 PYEFTLQYWHILA--ARLAFIIVFEHLVFGIKSFIAYLIPDVP 939 L YW +LA L FII FE++VF L+PDVP Sbjct: 623 GVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 665 >gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] Length = 494 Score = 68.9 bits (167), Expect = 2e-11 Identities = 74/266 (27%), Positives = 104/266 (39%), Gaps = 66/266 (24%) Query: 680 EECHPSGCLIDLCLQMGVIMFLKQIWNNFMEL----GYPLIQNWWSRHKIKRGIHDASIP 735 ++C P GC I + Q+ +IM KQ+ N+ E G P G +P Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP-------------GPDTPCLP 277 Query: 736 QWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFV 795 + LQFGF TIFV AF LAPL LLNN +EI LDA+KF+ Sbjct: 278 E-----------------------LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFL 314 Query: 796 TQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVE 855 +++RP+ R G ++ TNA + G N Sbjct: 315 CKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA---------------RSRLGYWLN--- 356 Query: 856 PSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILA--AR 913 + + G + F + ++ RY+ R L YW +LA Sbjct: 357 -GQGQILGRRRGGNAGFGVEIREPLQTPQPRYKASR-----DVGVNLALFYWKLLAVHVH 410 Query: 914 LAFIIVFEHLVFGIKSFIAYLIPDVP 939 L FII FE++VF L+PDVP Sbjct: 411 LGFIIAFENVVFFFLCPNDRLVPDVP 436 Score = 46.6 bits (109), Expect = 1e-04 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 33/146 (22%) Query: 462 KVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE----------- 510 K++ LFD+ GTVFF+IFM+ W + + L + WD +++++E Sbjct: 50 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 109 Query: 511 ------ETLRP---------------QFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLV 549 + + P +F A +M NP+TG EP+ ++ LL Sbjct: 110 CSDFQDQEVMPSSALHHWDCSDFQDQEFAALALQM-TQNPVTGLKEPYFQPHSCLSHLLT 168 Query: 550 SVSGIFFMISLVITAVFGVVVYRLVV 575 S + I ++ +V+ + V++Y ++ Sbjct: 169 SSAAILTVLCVVMIFLVSVIIYHGII 194 Score = 37.7 bits (86), Expect = 0.053 Identities = 14/23 (60%), Positives = 17/23 (73%) Query: 360 NNRHLLYERWARWGMWYKHQPLD 382 N+ LLY WA WG W+K+QPLD Sbjct: 23 NSCQLLYPYWACWGYWHKYQPLD 45 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 34.3 bits (77), Expect = 0.59 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 17 MNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTSITLISTD 76 M +S +T +T S R P +S S+S S ST+LF S+ ++ +PT T TD Sbjct: 91 MTSIESSVTSDTPGVSSTRMTP--TESRTTSESTSDSTTLFPSSTEDTSSPT--TPEGTD 146 Query: 77 KAEQVNTEENKNDSVLRCSFADLSDF 102 +EE+ + ++ S A L F Sbjct: 147 VPMSTPSEESISSTMAFVSTAPLPSF 172 >gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens] Length = 810 Score = 33.9 bits (76), Expect = 0.77 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 12 KQQKGMNISKS--EITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTS 69 K + +N+ S ++ L P R+++ A A K LS S+S+ Q ++ A Sbjct: 646 KAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKPLS-SSSVLQEPPAKKAAVAV 704 Query: 70 ITLISTDKAEQVNTEENKNDSVL 92 + L+S DK+ V EN DS++ Sbjct: 705 VPLVSEDKSVTVPEAENPRDSLV 727 >gi|5729862 stem-loop (histone) binding protein [Homo sapiens] Length = 270 Score = 31.6 bits (70), Expect = 3.8 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 100 SDFCLALGKDKDYTD-ESEHATYDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFK 158 SD+ A+ +D+ T E A Y R LINDF + KS + SK M+ + + + Sbjct: 73 SDWASAVEEDEMRTRVNKEMARYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDE 132 Query: 159 DGKKRIDYILVYRKTNIQYDKR-NTFEKNLRAEGL 192 R + Y K I YD+ ++LR G+ Sbjct: 133 SVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGI 167 >gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo sapiens] Length = 335 Score = 31.2 bits (69), Expect = 5.0 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599 SS+ + LL + G++F+ S+++ + + YR ++ E ++NF +++ +A Sbjct: 255 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 314 Query: 600 VCINFIIIMLLNLAYEK 616 + I+ L LA+++ Sbjct: 315 LS----SILFLYLAHKQ 327 >gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapiens] Length = 455 Score = 31.2 bits (69), Expect = 5.0 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599 SS+ + LL + G++F+ S+++ + + YR ++ E ++NF +++ +A Sbjct: 375 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 434 Query: 600 VCINFIIIMLLNLAYEK 616 + I+ L LA+++ Sbjct: 435 LS----SILFLYLAHKQ 447 >gi|7706704 G protein-coupled receptor 89B [Homo sapiens] Length = 455 Score = 31.2 bits (69), Expect = 5.0 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599 SS+ + LL + G++F+ S+++ + + YR ++ E ++NF +++ +A Sbjct: 375 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 434 Query: 600 VCINFIIIMLLNLAYEK 616 + I+ L LA+++ Sbjct: 435 LS----SILFLYLAHKQ 447 >gi|148234741 G protein-coupled receptor 89C [Homo sapiens] Length = 320 Score = 31.2 bits (69), Expect = 5.0 Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 540 SSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAA 599 SS+ + LL + G++F+ S+++ + + YR ++ E ++NF +++ +A Sbjct: 240 SSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSA 299 Query: 600 VCINFIIIMLLNLAYEK 616 + I+ L LA+++ Sbjct: 300 LS----SILFLYLAHKQ 312 >gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens] Length = 526 Score = 30.8 bits (68), Expect = 6.5 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 38 PCLAQSYAYSKSLSQSTSLFQSTESESQAPT---SITLISTDKAEQVNTEENKNDSVL 92 P L S + S S SQ+ + + S APT S+T+++TD A+Q +K + +L Sbjct: 18 PLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEIL 75 >gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] Length = 558 Score = 30.8 bits (68), Expect = 6.5 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 38 PCLAQSYAYSKSLSQSTSLFQSTESESQAPT---SITLISTDKAEQVNTEENKNDSVL 92 P L S + S S SQ+ + + S APT S+T+++TD A+Q +K + +L Sbjct: 18 PLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEIL 75 >gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sapiens] Length = 414 Score = 30.4 bits (67), Expect = 8.5 Identities = 12/23 (52%), Positives = 14/23 (60%) Query: 873 DLSELGMGKSGYCRYRDYRGPPW 895 D +LG+GK YCR D R PW Sbjct: 93 DALQLGLGKHNYCRNPDNRRRPW 115 >gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein [Homo sapiens] Length = 431 Score = 30.4 bits (67), Expect = 8.5 Identities = 12/23 (52%), Positives = 14/23 (60%) Query: 873 DLSELGMGKSGYCRYRDYRGPPW 895 D +LG+GK YCR D R PW Sbjct: 110 DALQLGLGKHNYCRNPDNRRRPW 132 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.138 0.437 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,460,986 Number of Sequences: 37866 Number of extensions: 1604783 Number of successful extensions: 5070 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 4899 Number of HSP's gapped (non-prelim): 70 length of query: 981 length of database: 18,247,518 effective HSP length: 112 effective length of query: 869 effective length of database: 14,006,526 effective search space: 12171671094 effective search space used: 12171671094 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.