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Search of human proteins with 110349788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
(2964 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 5972 0.0
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 468 e-131
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 201 9e-51
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 201 9e-51
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 188 6e-47
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 185 7e-46
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 185 7e-46
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 185 7e-46
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 185 7e-46
gi|197313748 SET domain containing 2 [Homo sapiens] 175 5e-43
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 100 4e-20
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 100 4e-20
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 97 2e-19
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 96 7e-19
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 94 3e-18
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 94 3e-18
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 89 6e-17
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 88 1e-16
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 88 1e-16
gi|210032580 SET domain containing 1B [Homo sapiens] 87 2e-16
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 86 7e-16
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 86 7e-16
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 85 9e-16
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 84 2e-15
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 82 8e-15
gi|55741677 SET domain containing 1A [Homo sapiens] 82 8e-15
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 82 8e-15
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 82 8e-15
gi|194294556 SET binding protein 1 isoform b [Homo sapiens] 78 1e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 77 2e-13
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 5972 bits (15494), Expect = 0.0
Identities = 2964/2964 (100%), Positives = 2964/2964 (100%)
Query: 1 MDPRNTAMLGLGSDSEGFSRKSPSAISTGTLVSKREVELEKNTKEEEDLRKRNRERNIEA 60
MDPRNTAMLGLGSDSEGFSRKSPSAISTGTLVSKREVELEKNTKEEEDLRKRNRERNIEA
Sbjct: 1 MDPRNTAMLGLGSDSEGFSRKSPSAISTGTLVSKREVELEKNTKEEEDLRKRNRERNIEA 60
Query: 61 GKDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHPR 120
GKDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHPR
Sbjct: 61 GKDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHPR 120
Query: 121 KALKSGKMTDEKNEHCPSKRDPSKLYKKADDVAAIECQSEEVIRLHSQGENNPLSKKLSP 180
KALKSGKMTDEKNEHCPSKRDPSKLYKKADDVAAIECQSEEVIRLHSQGENNPLSKKLSP
Sbjct: 121 KALKSGKMTDEKNEHCPSKRDPSKLYKKADDVAAIECQSEEVIRLHSQGENNPLSKKLSP 180
Query: 181 VHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKL 240
VHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKL
Sbjct: 181 VHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKL 240
Query: 241 GTGTTAGLVSKDLIRKAGVGSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLV 300
GTGTTAGLVSKDLIRKAGVGSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLV
Sbjct: 241 GTGTTAGLVSKDLIRKAGVGSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLV 300
Query: 301 NKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPGLVHKESGKKLG 360
NKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPGLVHKESGKKLG
Sbjct: 301 NKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPGLVHKESGKKLG 360
Query: 361 LGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKD 420
LGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKD
Sbjct: 361 LGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKD 420
Query: 421 AINLKAEALLPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEK 480
AINLKAEALLPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEK
Sbjct: 421 AINLKAEALLPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEK 480
Query: 481 FSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSPDFKMGGASDV 540
FSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSPDFKMGGASDV
Sbjct: 481 FSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSPDFKMGGASDV 540
Query: 541 STAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVG 600
STAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVG
Sbjct: 541 STAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVG 600
Query: 601 KNQFTSESTHLNVGHRSVGHSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSES 660
KNQFTSESTHLNVGHRSVGHSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSES
Sbjct: 601 KNQFTSESTHLNVGHRSVGHSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSES 660
Query: 661 SIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPLKKRKGRKPRWT 720
SIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPLKKRKGRKPRWT
Sbjct: 661 SIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPLKKRKGRKPRWT 720
Query: 721 KVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLP 780
KVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLP
Sbjct: 721 KVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLP 780
Query: 781 KLSKSTAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLE 840
KLSKSTAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLE
Sbjct: 781 KLSKSTAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLE 840
Query: 841 GPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSP 900
GPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSP
Sbjct: 841 GPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSP 900
Query: 901 VKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMS 960
VKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMS
Sbjct: 901 VKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMS 960
Query: 961 DLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHN 1020
DLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHN
Sbjct: 961 DLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHN 1020
Query: 1021 TVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQA 1080
TVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQA
Sbjct: 1021 TVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQA 1080
Query: 1081 AGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHS 1140
AGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHS
Sbjct: 1081 AGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHS 1140
Query: 1141 RQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSD 1200
RQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSD
Sbjct: 1141 RQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSD 1200
Query: 1201 SGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHDYL 1260
SGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHDYL
Sbjct: 1201 SGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHDYL 1260
Query: 1261 SYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIF 1320
SYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIF
Sbjct: 1261 SYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIF 1320
Query: 1321 RINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYP 1380
RINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYP
Sbjct: 1321 RINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYP 1380
Query: 1381 SYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPAKYH 1440
SYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPAKYH
Sbjct: 1381 SYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPAKYH 1440
Query: 1441 KKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQV 1500
KKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQV
Sbjct: 1441 KKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQV 1500
Query: 1501 SMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHRE 1560
SMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHRE
Sbjct: 1501 SMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHRE 1560
Query: 1561 PSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSCRVSNPN 1620
PSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSCRVSNPN
Sbjct: 1561 PSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSCRVSNPN 1620
Query: 1621 SSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNC 1680
SSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNC
Sbjct: 1621 SSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNC 1680
Query: 1681 SPTRKRSSSESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIAT 1740
SPTRKRSSSESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIAT
Sbjct: 1681 SPTRKRSSSESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIAT 1740
Query: 1741 ASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSSCSPHHIKRSVV 1800
ASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSSCSPHHIKRSVV
Sbjct: 1741 ASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSSCSPHHIKRSVV 1800
Query: 1801 EAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQA 1860
EAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQA
Sbjct: 1801 EAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQA 1860
Query: 1861 VVSMQAFQAAQFVNPELNRDEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWL 1920
VVSMQAFQAAQFVNPELNRDEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWL
Sbjct: 1861 VVSMQAFQAAQFVNPELNRDEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWL 1920
Query: 1921 LEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKK 1980
LEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKK
Sbjct: 1921 LEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKK 1980
Query: 1981 PPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQ 2040
PPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQ
Sbjct: 1981 PPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQ 2040
Query: 2041 KRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDT 2100
KRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDT
Sbjct: 2041 KRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDT 2100
Query: 2101 RKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPL 2160
RKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPL
Sbjct: 2101 RKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPL 2160
Query: 2161 KAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSC 2220
KAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSC
Sbjct: 2161 KAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSC 2220
Query: 2221 DPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIG 2280
DPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIG
Sbjct: 2221 DPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIG 2280
Query: 2281 GKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENINTPTRLTP 2340
GKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENINTPTRLTP
Sbjct: 2281 GKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENINTPTRLTP 2340
Query: 2341 QLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDG 2400
QLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDG
Sbjct: 2341 QLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDG 2400
Query: 2401 NIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQ 2460
NIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQ
Sbjct: 2401 NIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQ 2460
Query: 2461 ALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKY 2520
ALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKY
Sbjct: 2461 ALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKY 2520
Query: 2521 YGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDV 2580
YGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDV
Sbjct: 2521 YGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDV 2580
Query: 2581 IRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHY 2640
IRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHY
Sbjct: 2581 IRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHY 2640
Query: 2641 AQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIE 2700
AQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIE
Sbjct: 2641 AQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIE 2700
Query: 2701 KLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLY 2760
KLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLY
Sbjct: 2701 KLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLY 2760
Query: 2761 TYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFS 2820
TYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFS
Sbjct: 2761 TYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFS 2820
Query: 2821 PHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAANEIPSLEEPE 2880
PHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAANEIPSLEEPE
Sbjct: 2821 PHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAANEIPSLEEPE 2880
Query: 2881 REGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTY 2940
REGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTY
Sbjct: 2881 REGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTY 2940
Query: 2941 LLEEGSGRKLRRRTLFIPENSFRK 2964
LLEEGSGRKLRRRTLFIPENSFRK
Sbjct: 2941 LLEEGSGRKLRRRTLFIPENSFRK 2964
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 468 bits (1204), Expect = e-131
Identities = 402/1243 (32%), Positives = 574/1243 (46%), Gaps = 168/1243 (13%)
Query: 778 RLPKLSK---STAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSK 834
R+PKLSK + +PS+ L K V + + P R P+ +
Sbjct: 463 RVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQ 522
Query: 835 EMPQLEGPPKRTLKIPASK------VFSLQSKEEQEPPI---LQPEIEIPSFKQGLSV-S 884
P+ + T P V + K EPP + P + + L+V +
Sbjct: 523 H-PKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVIT 581
Query: 885 PFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQD 944
P KKRGRPK+Q V+ S +P SP E R QL
Sbjct: 582 PVKKKRGRPKKQPLLTVETIHEGTSTSPV----SPISREFPGTKKRKRRRNLAKLAQLVP 637
Query: 945 PDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSS 1004
+D S EM+ KK+ K G L K I+ INKMKTLKRK +LNQILS
Sbjct: 638 GEDKPMS-----------EMKFHKKVGKL--GVLDKKTIKTINKMKTLKRKNILNQILSC 684
Query: 1005 SVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILS 1064
S + K K + S AA SKLG+QINVSK+GTIYIGK+RGRKP+ L
Sbjct: 685 SSSVALKAKAPPE----TSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSE 740
Query: 1065 GSPTSLAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSD 1124
T++ + Q A+ P S +SS P+ +Q G++G SP S++
Sbjct: 741 EPKTAIKHPRPVSSQPDVPAV----PSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTE 796
Query: 1125 AGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEAT 1184
F E ++P L + S + T K G +LSPP L+ NSPSHL E+ SLKE T
Sbjct: 797 TNFSELKTMPNL----QPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEIT 852
Query: 1185 PSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSL 1244
SP+SESHS+ETIPSDSGIGTDNNSTSD+AEK + +RR+SF+ SL PE +S
Sbjct: 853 LSPVSESHSEETIPSDSGIGTDNNSTSDQAEK-SSESRRRYSFDFCSLDNPEAIPSDTST 911
Query: 1245 KEKHKHKCKRRNHD-YLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRI 1303
K +H H+ K D +L+++ +K+ K KRK+K L+NR D F+A+LEELI++ RI
Sbjct: 912 KNRHGHRQKHLIVDNFLAHESLKKPKHKRKRK--SLQNRDDLQFLADLEELITKFQVFRI 969
Query: 1304 THRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKP-DLK--KKRGRPPKMREAM 1360
+HRS+ F + P+IFRINF+ +Y P DPL Y+R+ DLK KKRGRP K + M
Sbjct: 970 SHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTM 1029
Query: 1361 AEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPP----PPSPS 1416
++PF+ S+P+ S +Y YGMPY+ P+ + LGYYG+YP LY SP
Sbjct: 1030 TKVPFLQGFSYPIPSGSYYAPYGMPYTSMPM----MNLGYYGQYPAPLYLSHTLGAASPF 1085
Query: 1417 FTTPLPPPSYMHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYG 1476
+PPP + H+ ++ A HK KH + Q S++ ++ G
Sbjct: 1086 MRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSG 1145
Query: 1477 WMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRC 1536
+ + KH+H+HKH+E R + T + S L + K F + ER +K
Sbjct: 1146 RLHKRKHKHKHKHKEDRI-------LGTHDNLSGLFAGKATGFSSHILSERLSSADKEL- 1197
Query: 1537 HMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSE 1596
P S N+ ++ + SE+ A + ++D +LS +
Sbjct: 1198 --------PLVSEKNKHKEKQKHQHSEAGHKAS--KNNFEVD------TLSTLSLSDAQH 1241
Query: 1597 PASSDEHTNLFTSAIGSC--RVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNE 1654
+ E +L + + SC R S G +++ +FS E PSN+
Sbjct: 1242 WTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFS------------EMNPSND 1289
Query: 1655 RAVQTLAGSQPTSDKP--SQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDD 1712
+ ++GS+ S + + R + RK SS +S + G+PS ++ +
Sbjct: 1290 KWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSP-GMPSPHLKVDQTAVH 1348
Query: 1713 SVDSLLQRMVQNEDQEP--MEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAV 1770
S +NE P M + A + + + PP+ P S L A
Sbjct: 1349 S---------KNEGSVPTMMTRKKPAAVDSVTIPPA--PVLS-----------LLAASAA 1386
Query: 1771 TSDSCNNSISLLSEKLTSSCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKIL 1830
TSD+ +S+ KR +EA+Q + RKMCNY KIL+TKKNLDHVNKIL
Sbjct: 1387 TSDAVGSSLK------------KRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKIL 1434
Query: 1831 KAKKLQRQARTGNNFVKRRPGRPRKCPLQ----AVVSMQAFQAAQFVNPELNRDEEGAAL 1886
KAK+LQRQ++TGNNFVK+R GRPRK P Q + M + + + + + L
Sbjct: 1435 KAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPL 1494
Query: 1887 HLSP----DTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNK 1942
L P DT+ IEAV+ P PLP
Sbjct: 1495 VLEPAASQDTIMATIEAVIHMAREAP--------------PLPPPPPPPLPP-------- 1532
Query: 1943 SFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKKPPRPP 1985
P +P P P P + +P P ++ PP+ P
Sbjct: 1533 ---PPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQP 1572
Score = 82.4 bits (202), Expect = 6e-15
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 35/295 (11%)
Query: 40 EKNTKEEEDLRKRNRERNIEAGKD-------DGLTDAQQQFSVKETNFSEGNLKLKIGLQ 92
E+ EEED R+ + + D DGL + Q+FS+KE NF+EG+LKLKI
Sbjct: 53 ERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEE--QEFSIKEANFTEGSLKLKIQT- 109
Query: 93 AKRTKKPPKNLENYVCRPAIKTTIKHP-----RKALKSGKMTDEKNEHCPSKRDPSKLYK 147
KR KKPPKNLENY+C P IK TIK +A K+ K T E+ K+ +
Sbjct: 110 TKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDL 169
Query: 148 KADDVAAIECQSEEVIRLHSQGENNP------LSKKLSPVHSEMADYINATPSTLLGSRD 201
A D+ + Q+ E + HS + L P H + + N +
Sbjct: 170 AASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSG 229
Query: 202 PDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVS---KDLIRKAG 258
P ++ + T +++ A P + +K + KK G T +S KDL+
Sbjct: 230 PVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLL---- 285
Query: 259 VGSVAGIIHKDLIKKPTISTA-----VGLVTKDPG--KKPVFNAAVGLVNKDSVK 306
+G VA P S+A LV +D G K+P VG K S K
Sbjct: 286 LGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKK 340
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 201 bits (511), Expect = 9e-51
Identities = 111/272 (40%), Positives = 163/272 (59%), Gaps = 26/272 (9%)
Query: 2062 KKPDVPLYKKIRSN-----VYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAE 2116
KKP P YK I+ N V + LS E CNCK D++ G +C+NRM+ E
Sbjct: 1596 KKP--PPYKHIKVNRPIGRVQIFTADLS--EIPRCNCKATDENPC-GIDSECINRMLLYE 1650
Query: 2117 CSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSE 2176
C P CP G +C NQ + ++ + +E FR ++GWG+RTK +K G+F+ EY+GE++ E
Sbjct: 1651 CHPTVCPAGGRCQNQCFSKRQYPE-VEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDE 1709
Query: 2177 QEFRNRM-IEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVY 2235
+E R R+ Q H+ ++ Y L LD +ID+ GN ARF+NH C PNCE QKWSVNG
Sbjct: 1710 EECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDT 1769
Query: 2236 RIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNS 2295
R+GL+AL D+ AGTELT++YN K +CKCG C G +G + + +
Sbjct: 1770 RVGLFALSDIKAGTELTFNYNLECLGNGK-TVCKCGAPNCSGFLGVRPK----------N 1818
Query: 2296 QPMATHKKSGRSKEKRKSKHKLKKRRGHLSEE 2327
QP+AT +KS + K+K++ K ++ +G +++E
Sbjct: 1819 QPIATEEKSKKFKKKQQGK---RRTQGEITKE 1847
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 201 bits (511), Expect = 9e-51
Identities = 111/272 (40%), Positives = 163/272 (59%), Gaps = 26/272 (9%)
Query: 2062 KKPDVPLYKKIRSN-----VYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAE 2116
KKP P YK I+ N V + LS E CNCK D++ G +C+NRM+ E
Sbjct: 1865 KKP--PPYKHIKVNRPIGRVQIFTADLS--EIPRCNCKATDENPC-GIDSECINRMLLYE 1919
Query: 2117 CSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSE 2176
C P CP G +C NQ + ++ + +E FR ++GWG+RTK +K G+F+ EY+GE++ E
Sbjct: 1920 CHPTVCPAGGRCQNQCFSKRQYPE-VEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDE 1978
Query: 2177 QEFRNRM-IEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVY 2235
+E R R+ Q H+ ++ Y L LD +ID+ GN ARF+NH C PNCE QKWSVNG
Sbjct: 1979 EECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDT 2038
Query: 2236 RIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNS 2295
R+GL+AL D+ AGTELT++YN K +CKCG C G +G + + +
Sbjct: 2039 RVGLFALSDIKAGTELTFNYNLECLGNGK-TVCKCGAPNCSGFLGVRPK----------N 2087
Query: 2296 QPMATHKKSGRSKEKRKSKHKLKKRRGHLSEE 2327
QP+AT +KS + K+K++ K ++ +G +++E
Sbjct: 2088 QPIATEEKSKKFKKKQQGK---RRTQGEITKE 2116
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 188 bits (478), Expect = 6e-47
Identities = 100/261 (38%), Positives = 151/261 (57%), Gaps = 13/261 (4%)
Query: 2062 KKPDVPLYKKIRSN-----VYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAE 2116
+KP P YK I++N V + V LS E CNCK P D+ G +CLNRM+ E
Sbjct: 1068 RKP--PPYKHIKANKVIGKVQIQVADLS--EIPRCNCK-PADENPCGLESECLNRMLQYE 1122
Query: 2117 CSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSE 2176
C P CP G++C NQ + + E + E +GWG+RTK +K G+F+ EY+GE++ E
Sbjct: 1123 CHPQVCPAGDRCQNQCFTKRLYPDA-EIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDE 1181
Query: 2177 QEFRNRMIEQYHNH-SDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVY 2235
+E R R+ + N ++ Y L + +ID+ GN +RF+NHSC+PNCE QKW+VNG
Sbjct: 1182 EECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDV 1241
Query: 2236 RIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNS 2295
R+GL+AL D+PAG ELT++YN + + C CG + C G +G + + T+ + +
Sbjct: 1242 RVGLFALCDIPAGMELTFNYNLDCLGNGRTE-CHCGADNCSGFLGVRPKSACASTNEEKA 1300
Query: 2296 QPMATHKKSGRSKEKRKSKHK 2316
+ +K + K + K H+
Sbjct: 1301 KNAKLKQKRRKIKTEPKQMHE 1321
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 185 bits (469), Expect = 7e-46
Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)
Query: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118
+KP P YK I+ N V + E CNCK P D+ G +CLNRM+ EC
Sbjct: 986 RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
Query: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178
P CP GE C NQ + ++ + + + + KGWG+ K ++ G+F+ EY+GE++ E+E
Sbjct: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
Query: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237
R+ + N H Y L +D +ID+ GN +RF+NHSC PNCE KW+VNG R+
Sbjct: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
Query: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297
GL+A+ D+PAGTELT++YN EK +C+CG C G +G + + L+S + +
Sbjct: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
Query: 2298 MATHKKSGRSKEKRKSKHK 2316
T KK+ R + K + K +
Sbjct: 1220 -KTKKKTRRRRAKGEGKRQ 1237
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 185 bits (469), Expect = 7e-46
Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)
Query: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118
+KP P YK I+ N V + E CNCK P D+ G +CLNRM+ EC
Sbjct: 986 RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
Query: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178
P CP GE C NQ + ++ + + + + KGWG+ K ++ G+F+ EY+GE++ E+E
Sbjct: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
Query: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237
R+ + N H Y L +D +ID+ GN +RF+NHSC PNCE KW+VNG R+
Sbjct: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
Query: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297
GL+A+ D+PAGTELT++YN EK +C+CG C G +G + + L+S + +
Sbjct: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
Query: 2298 MATHKKSGRSKEKRKSKHK 2316
T KK+ R + K + K +
Sbjct: 1220 -KTKKKTRRRRAKGEGKRQ 1237
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 185 bits (469), Expect = 7e-46
Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)
Query: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118
+KP P YK I+ N V + E CNCK P D+ G +CLNRM+ EC
Sbjct: 986 RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
Query: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178
P CP GE C NQ + ++ + + + + KGWG+ K ++ G+F+ EY+GE++ E+E
Sbjct: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
Query: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237
R+ + N H Y L +D +ID+ GN +RF+NHSC PNCE KW+VNG R+
Sbjct: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
Query: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297
GL+A+ D+PAGTELT++YN EK +C+CG C G +G + + L+S + +
Sbjct: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
Query: 2298 MATHKKSGRSKEKRKSKHK 2316
T KK+ R + K + K +
Sbjct: 1220 -KTKKKTRRRRAKGEGKRQ 1237
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 185 bits (469), Expect = 7e-46
Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)
Query: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118
+KP P YK I+ N V + E CNCK P D+ G +CLNRM+ EC
Sbjct: 986 RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
Query: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178
P CP GE C NQ + ++ + + + + KGWG+ K ++ G+F+ EY+GE++ E+E
Sbjct: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
Query: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237
R+ + N H Y L +D +ID+ GN +RF+NHSC PNCE KW+VNG R+
Sbjct: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
Query: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297
GL+A+ D+PAGTELT++YN EK +C+CG C G +G + + L+S + +
Sbjct: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
Query: 2298 MATHKKSGRSKEKRKSKHK 2316
T KK+ R + K + K +
Sbjct: 1220 -KTKKKTRRRRAKGEGKRQ 1237
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 175 bits (444), Expect = 5e-43
Identities = 109/311 (35%), Positives = 165/311 (53%), Gaps = 29/311 (9%)
Query: 1984 PPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKRI 2043
P KK+ Q ++ ++ L KK ++E GE P VG
Sbjct: 1403 PLKKRRQ------EIESDSESDGELQDRKKVRVEVEQGETSVP--PGSALVGPSCVMD-- 1452
Query: 2044 DFQLPYDILWQWKHNQLYKKPDVPLY-KKIRSNVYVDVKPLS----GYEATTCNCKKPDD 2098
DF+ P +WK + K+ +P Y I NVY+ + + + C C
Sbjct: 1453 DFRDPQ----RWK--ECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSK 1506
Query: 2099 DTRK----GCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGI 2154
D R C +DCLNR++ ECS + CP G+ C N+R QR + +E E+KGWG+
Sbjct: 1507 DERAQGEIACGEDCLNRLLMIECS-SRCPNGDYCSNRRFQRKQHAD-VEVILTEKKGWGL 1564
Query: 2155 RTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYC-LNLDSGMVIDSYRMGNEA 2213
R + L + F++EY GEV+ +EF+ R+ E N + HY + L + +ID+ + GN +
Sbjct: 1565 RAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCS 1624
Query: 2214 RFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFE 2273
RF+NHSC+PNCE QKW+VNG R+G + K +P+G+ELT+DY F + E Q+ C CG
Sbjct: 1625 RFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQK-CFCGSA 1683
Query: 2274 KCRGIIGGKSQ 2284
CRG +GG+++
Sbjct: 1684 NCRGYLGGENR 1694
Score = 33.5 bits (75), Expect = 3.2
Identities = 58/262 (22%), Positives = 99/262 (37%), Gaps = 36/262 (13%)
Query: 1762 PDSLLVPAVTSDSCNNSIS-LLSEKLTSSCSPHHIKRSVVEAMQRQARKMCNYDKILATK 1820
P + V ++T C + S +L L S S +K + E + + + K A++
Sbjct: 887 PPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASR 946
Query: 1821 KNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNRD 1880
+N N L K LQ GN+ + R GR PE++ D
Sbjct: 947 EN--RRNNGLSGKCLQEAQEEGNSILPERRGR----------------------PEISLD 982
Query: 1881 EEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQEN 1940
E G H+ ++V+ + +NL E G+ + L+ + + ++
Sbjct: 983 ERGEGGHVHTSDDSEVVFSSC-DLNLTMEDSDGVT---YALKCDSSGHAPEIVSTVHEDY 1038
Query: 1941 NKSFNEAPVEIPSPSETPAKPSEPESTLQPVL-----SLIPREKKPPRPPKKKYQKAGLY 1995
+ S + E S S P + LQ V+ S +P E+ P + Q Y
Sbjct: 1039 SGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSS-QSYRHY 1097
Query: 1996 SDVYKTTDPKSRLIQLKKEKLE 2017
SD ++ +SR L +EK E
Sbjct: 1098 SDHWEDERLESRR-HLYEEKFE 1118
Score = 33.1 bits (74), Expect = 4.2
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 15/108 (13%)
Query: 1331 PSFPLDPLHYIRKPDLKKKRG---------RPPKMREAMAEMPF----MHSLSFPLSSTG 1377
P+ P PL P +K + G PPK R + ++ F +H S PL +T
Sbjct: 101 PNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATT 160
Query: 1378 FYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPS 1425
+ P +PL A I PP+ PPPP P+ T L P+
Sbjct: 161 TAVA-SPPTHAAPLPAV-IAESTTVDSPPSSPPPPPPPAQATTLSSPA 206
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 99.8 bits (247), Expect = 4e-20
Identities = 60/184 (32%), Positives = 90/184 (48%), Gaps = 19/184 (10%)
Query: 2091 CNCKKPDDDTRKGC-------VDDCLNRMIFAECSPNTC-PCGE---------QCCNQRI 2133
C C + GC C + EC P+ C CG C N I
Sbjct: 508 CQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 567
Query: 2134 QRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDH 2193
QR L ++ GWGI K+P++ +FI EY GE++S+ E +R + Y +
Sbjct: 568 QRGSKKHLLLA-PSDVAGWGIFIKDPVQKNEFISEYCGEIISQDE-ADRRGKVYDKYMCS 625
Query: 2194 YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTY 2253
+ NL++ V+D+ R GN+ RF NHS +PNC + VNG +RIG++A + + G EL +
Sbjct: 626 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 685
Query: 2254 DYNF 2257
DY +
Sbjct: 686 DYRY 689
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 99.8 bits (247), Expect = 4e-20
Identities = 60/184 (32%), Positives = 90/184 (48%), Gaps = 19/184 (10%)
Query: 2091 CNCKKPDDDTRKGC-------VDDCLNRMIFAECSPNTC-PCGE---------QCCNQRI 2133
C C + GC C + EC P+ C CG C N I
Sbjct: 552 CQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 611
Query: 2134 QRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDH 2193
QR L ++ GWGI K+P++ +FI EY GE++S+ E +R + Y +
Sbjct: 612 QRGSKKHLLLA-PSDVAGWGIFIKDPVQKNEFISEYCGEIISQDE-ADRRGKVYDKYMCS 669
Query: 2194 YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTY 2253
+ NL++ V+D+ R GN+ RF NHS +PNC + VNG +RIG++A + + G EL +
Sbjct: 670 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 729
Query: 2254 DYNF 2257
DY +
Sbjct: 730 DYRY 733
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 97.1 bits (240), Expect = 2e-19
Identities = 91/323 (28%), Positives = 152/323 (47%), Gaps = 51/323 (15%)
Query: 2001 TTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQK---RIDFQLPYDILWQWKH 2057
+ D + L Q+KK K TP ++ L PA + +Y+ +K RI Q D L + K+
Sbjct: 34 SNDKHNYLSQVKKGKA-ITPKDNNKTLKPA---IAEYIVKKAKQRIALQRWQDELNRRKN 89
Query: 2058 NQ--LYKKPDVPLYKKIRSNVYV-DVKPLSGYEAT---TCNCKKPDDDTRKGCVDDC--- 2108
++ ++ + V L Y+ + KP G T C D +K C +
Sbjct: 90 HKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVL 149
Query: 2109 ----LNRMI-------FAECSPNTCPCGEQCCNQRIQRH-EWVQCLERFRAEEKGWGIRT 2156
N+ I EC+ + C CG C N+ +Q+ ++ C+ R + +GWG++T
Sbjct: 150 LAYNKNQQIKIPPGTPIYECN-SRCQCGPDCPNRIVQKGTQYSLCIFR-TSNGRGWGVKT 207
Query: 2157 KEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLD---SGMVIDSYRMGNEA 2213
+K F++EY+GEV++ +E R + Y N Y +LD +D+ R GN +
Sbjct: 208 LVKIKRMSFVMEYVGEVITSEEAERRG-QFYDNKGITYLFDLDYESDEFTVDAARYGNVS 266
Query: 2214 RFINHSCDPNCEMQKWSVNG----VYRIGLYALKDMPAGTELTYDYNF------------ 2257
F+NHSCDPN ++ ++ + RI L++ + + AG ELT+DY
Sbjct: 267 HFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSID 326
Query: 2258 HSFNVEK-QQLCKCGFEKCRGII 2279
HS ++ + +CKCG CRG +
Sbjct: 327 HSPAKKRVRTVCKCGAVTCRGYL 349
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 95.5 bits (236), Expect = 7e-19
Identities = 60/184 (32%), Positives = 89/184 (48%), Gaps = 19/184 (10%)
Query: 2091 CNCKKPDDDTRKGC-------VDDCLNRMIFAECSPNTC-PCGEQ---------CCNQRI 2133
C C + GC C + EC P+ C CG C N I
Sbjct: 548 CQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
Query: 2134 QRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDH 2193
QR L ++ GWG KE ++ +FI EY GE++S+ E +R + Y +
Sbjct: 608 QRGLKKHLLLA-PSDVAGWGTFIKESVQKNEFISEYCGELISQDE-ADRRGKVYDKYMSS 665
Query: 2194 YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTY 2253
+ NL++ V+D+ R GN+ RF NHS +PNC + VNG +RIG++A + + AG EL +
Sbjct: 666 FLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
Query: 2254 DYNF 2257
DY +
Sbjct: 726 DYRY 729
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 93.6 bits (231), Expect = 3e-18
Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 4/134 (2%)
Query: 2145 FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYC--LNLDSGM 2202
+R+ G G+ K + AG+ +IEY G V+ + R E+Y++ C +D
Sbjct: 3834 YRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR--EKYYDSKGIGCYMFRIDDSE 3891
Query: 2203 VIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNV 2262
V+D+ GN ARFINHSC+PNC + +++G I ++A++ + G ELTYDY F +
Sbjct: 3892 VVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDA 3951
Query: 2263 EKQQLCKCGFEKCR 2276
+ C CG +KCR
Sbjct: 3952 SNKLPCNCGAKKCR 3965
Score = 32.0 bits (71), Expect = 9.3
Identities = 41/186 (22%), Positives = 66/186 (35%), Gaps = 16/186 (8%)
Query: 430 LPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIIN 489
LPT EP+ +S S++I+ +E EL L + T V S L S E
Sbjct: 2901 LPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGE--- 2957
Query: 490 LEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSPDFKMGGASDVSTAKSPFSA 549
+ I + S +SSE S P +PD + G D SP
Sbjct: 2958 -------KRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCG 3010
Query: 550 VGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSEST 609
E + LTR+ Q+ +P + + + ++S G +Q ++ +
Sbjct: 3011 SVEQGHGNN------QDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAV 3064
Query: 610 HLNVGH 615
H
Sbjct: 3065 QTTPPH 3070
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 93.6 bits (231), Expect = 3e-18
Identities = 58/192 (30%), Positives = 95/192 (49%), Gaps = 35/192 (18%)
Query: 2116 ECSPNTCPCGEQCCNQRIQRH-EWVQCLERFRAEE-KGWGIRTKEPLKAGQFIIEYLGEV 2173
EC+ + C CG C N+ +Q+ + C+ FR ++ +GWG+RT E ++ F++EY+GE+
Sbjct: 221 ECN-SRCRCGYDCPNRVVQKGIRYDLCI--FRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
Query: 2174 VSEQEFRNRMIEQYHNHSDHYCLNLD---SGMVIDSYRMGNEARFINHSCDPNCEMQKWS 2230
++ +E R + Y Y +LD +D+ GN + F+NHSCDPN ++
Sbjct: 278 ITSEEAERRG-QIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVF 336
Query: 2231 VNG----VYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQL------------------- 2267
++ + RI +A + + AG ELT+DYN V+ +
Sbjct: 337 IDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRV 396
Query: 2268 ---CKCGFEKCR 2276
CKCG E CR
Sbjct: 397 RIECKCGTESCR 408
>gi|194306650 SET domain and mariner transposase fusion [Homo sapiens]
Length = 684
Score = 89.0 bits (219), Expect = 6e-17
Identities = 62/215 (28%), Positives = 111/215 (51%), Gaps = 27/215 (12%)
Query: 2090 TCNCKKPDDD-TRKGCVDDCLNRMIFAE----CSPNTCPCGEQCCNQRIQRHEWVQCLER 2144
TC+C + ++ C+ D + +AE C+ C C + C N+ +Q+ +
Sbjct: 86 TCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFH-FQV 143
Query: 2145 FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCL---NLDSG 2201
F+ +KGWG+RT E + G+F+ EY GEV+ E + R+ Q + S++ ++ +G
Sbjct: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIREHVYNG 203
Query: 2202 MVIDSY----RMGNEARFINHSCDPNCEMQKWSVNG-VYRIGLYALKDMPAGTELTYDYN 2256
V++++ +GN RF+NHSC+PN M ++ V ++ L+A KD+ EL+YDY+
Sbjct: 204 QVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDYS 263
Query: 2257 FHSFNV----EKQQL--------CKCGFEKCRGII 2279
N+ +K++L C CG + C +
Sbjct: 264 GRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/170 (34%), Positives = 92/170 (54%), Gaps = 18/170 (10%)
Query: 2116 ECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVS 2175
EC+ C C C N+ +Q V+ L+ +R + GWG+R + + G FI EY+GE++S
Sbjct: 982 ECN-QACSCWRNCKNRVVQSGIKVR-LQLYRTAKMGWGVRALQTIPQGTFICEYVGELIS 1039
Query: 2176 EQEFRNRMIEQYHNHSDHYCLNLDS--GMV--IDSYRMGNEARFINHSCDPN-CEMQKWS 2230
+ E R D Y +LD+ G V ID+ GN +RFINH CDPN ++ +
Sbjct: 1040 DAEADVR-------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFM 1092
Query: 2231 VN---GVYRIGLYALKDMPAGTELTYDYNFHSFNVE-KQQLCKCGFEKCR 2276
++ RI ++ +D+ G EL +DY ++++ K C+CG EKC+
Sbjct: 1093 LHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCK 1142
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/170 (34%), Positives = 92/170 (54%), Gaps = 18/170 (10%)
Query: 2116 ECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVS 2175
EC+ C C C N+ +Q V+ L+ +R + GWG+R + + G FI EY+GE++S
Sbjct: 1016 ECN-QACSCWRNCKNRVVQSGIKVR-LQLYRTAKMGWGVRALQTIPQGTFICEYVGELIS 1073
Query: 2176 EQEFRNRMIEQYHNHSDHYCLNLDS--GMV--IDSYRMGNEARFINHSCDPN-CEMQKWS 2230
+ E R D Y +LD+ G V ID+ GN +RFINH CDPN ++ +
Sbjct: 1074 DAEADVR-------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFM 1126
Query: 2231 VN---GVYRIGLYALKDMPAGTELTYDYNFHSFNVE-KQQLCKCGFEKCR 2276
++ RI ++ +D+ G EL +DY ++++ K C+CG EKC+
Sbjct: 1127 LHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCK 1176
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 87.0 bits (214), Expect = 2e-16
Identities = 45/130 (34%), Positives = 71/130 (54%), Gaps = 5/130 (3%)
Query: 2152 WGIRTKEPLKAGQFIIEYLGEVVSE--QEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRM 2209
WG+ EP+ A + +IEY+G+ + + + R + E Y +D +ID+ +
Sbjct: 1796 WGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYED-EGIGSSYMFRVDHDTIIDATKC 1854
Query: 2210 GNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCK 2269
GN ARFINHSC+PNC + +V +I +Y+ + + E+TYDY F +V+ C
Sbjct: 1855 GNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIP--CL 1912
Query: 2270 CGFEKCRGII 2279
CG E CRG +
Sbjct: 1913 CGSENCRGTL 1922
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 85.5 bits (210), Expect = 7e-16
Identities = 67/262 (25%), Positives = 110/262 (41%), Gaps = 33/262 (12%)
Query: 2642 QPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEK 2701
+PGC YF L +D+ L+ GDCV++ P + RIEK
Sbjct: 1110 EPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPR--------------------VGRIEK 1149
Query: 2702 LWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYT 2761
+W + F +G + P ET H P++ FY E+F L E P+ ++G C VL
Sbjct: 1150 VWVRDGAAYF-YGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKD 1208
Query: 2762 YCKGRPKGVKEQDVYICDYRL---DKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKD 2818
+ RP + E D+ +C+ R DK F + R +F K + P+K+
Sbjct: 1209 FLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKE 1268
Query: 2819 FSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDD------ALPLIEEVLASQEQAANE 2872
SP + + + + E ++++G+ED +LP ++ LAS+
Sbjct: 1269 PSP--LLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPY 1326
Query: 2873 IPSLEEPEREGATANVSEGEKK 2894
P P+ +A EG K+
Sbjct: 1327 TPPQSTPKSAKGSAK-KEGSKR 1347
Score = 73.6 bits (179), Expect = 3e-12
Identities = 31/101 (30%), Positives = 58/101 (57%)
Query: 2699 IEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLD 2758
IE+LW++ E++ +G ++RP+ET H +R+F E+F+ Y +P+ ++G C V+
Sbjct: 948 IERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMF 1007
Query: 2759 LYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPV 2799
+ Y K P+ +++DV++C+ R F KI P+
Sbjct: 1008 VKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1048
Score = 64.7 bits (156), Expect = 1e-09
Identities = 32/99 (32%), Positives = 50/99 (50%)
Query: 2446 EICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEA 2505
E+ + I YKD + L + P ++ DYYE +S P+DL+ I++++ Y V
Sbjct: 52 ELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNL 111
Query: 2506 FDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
AD +F NA+ YY SP + C+L Y R+E
Sbjct: 112 LTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNE 150
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/129 (25%), Positives = 72/129 (55%)
Query: 2444 FKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTV 2503
F ++ D + S +++ Q +A P +LP KKK DYY++I P+ L I ++ Y+T+
Sbjct: 354 FYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETL 413
Query: 2504 EAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSS 2563
+ + D+ +F NA++Y S + + V +L++ + E + + D G++ + +S
Sbjct: 414 DHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATS 473
Query: 2564 ETSVSEKEN 2572
+T +++++
Sbjct: 474 DTGSAKRKS 482
Score = 58.5 bits (140), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%)
Query: 2433 EVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIE 2492
E + A L +I +++ + I+ + S + ++ LP K + DYY I +P+DL TI
Sbjct: 175 EGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIA 234
Query: 2493 KQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
++I G YK++ A D+ + +NA+ Y S V +D ++K +Y + E
Sbjct: 235 QRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAE 286
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 2440 LAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGY 2499
+ Q E+ + + +Y D + L+A L LP + + DYY I P+D+ I ++
Sbjct: 626 MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANK 685
Query: 2500 YKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIV 2553
Y+ +++ D + +F NA Y +S + +D L K R + D V
Sbjct: 686 YQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHV 739
Score = 45.4 bits (106), Expect = 8e-04
Identities = 30/82 (36%), Positives = 35/82 (42%)
Query: 2470 PPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGR 2529
P KK DYY+ I +P+DL IE I Y E DM +FRNA Y S V
Sbjct: 518 PSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYN 577
Query: 2530 DVCRLRKAYYNARHEASAQIDE 2551
D L K R E D+
Sbjct: 578 DAHILEKLLKEKRKELGPLPDD 599
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 85.5 bits (210), Expect = 7e-16
Identities = 67/262 (25%), Positives = 110/262 (41%), Gaps = 33/262 (12%)
Query: 2642 QPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEK 2701
+PGC YF L +D+ L+ GDCV++ P + RIEK
Sbjct: 1142 EPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPR--------------------VGRIEK 1181
Query: 2702 LWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYT 2761
+W + F +G + P ET H P++ FY E+F L E P+ ++G C VL
Sbjct: 1182 VWVRDGAAYF-YGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKD 1240
Query: 2762 YCKGRPKGVKEQDVYICDYRL---DKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKD 2818
+ RP + E D+ +C+ R DK F + R +F K + P+K+
Sbjct: 1241 FLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKE 1300
Query: 2819 FSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDD------ALPLIEEVLASQEQAANE 2872
SP + + + + E ++++G+ED +LP ++ LAS+
Sbjct: 1301 PSP--LLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPY 1358
Query: 2873 IPSLEEPEREGATANVSEGEKK 2894
P P+ +A EG K+
Sbjct: 1359 TPPQSTPKSAKGSAK-KEGSKR 1379
Score = 73.6 bits (179), Expect = 3e-12
Identities = 31/101 (30%), Positives = 58/101 (57%)
Query: 2699 IEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLD 2758
IE+LW++ E++ +G ++RP+ET H +R+F E+F+ Y +P+ ++G C V+
Sbjct: 980 IERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMF 1039
Query: 2759 LYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPV 2799
+ Y K P+ +++DV++C+ R F KI P+
Sbjct: 1040 VKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1080
Score = 64.7 bits (156), Expect = 1e-09
Identities = 32/99 (32%), Positives = 50/99 (50%)
Query: 2446 EICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEA 2505
E+ + I YKD + L + P ++ DYYE +S P+DL+ I++++ Y V
Sbjct: 52 ELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNL 111
Query: 2506 FDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
AD +F NA+ YY SP + C+L Y R+E
Sbjct: 112 LTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNE 150
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/129 (25%), Positives = 72/129 (55%)
Query: 2444 FKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTV 2503
F ++ D + S +++ Q +A P +LP KKK DYY++I P+ L I ++ Y+T+
Sbjct: 386 FYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETL 445
Query: 2504 EAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSS 2563
+ + D+ +F NA++Y S + + V +L++ + E + + D G++ + +S
Sbjct: 446 DHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATS 505
Query: 2564 ETSVSEKEN 2572
+T +++++
Sbjct: 506 DTGSAKRKS 514
Score = 58.5 bits (140), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%)
Query: 2433 EVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIE 2492
E + A L +I +++ + I+ + S + ++ LP K + DYY I +P+DL TI
Sbjct: 175 EGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIA 234
Query: 2493 KQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
++I G YK++ A D+ + +NA+ Y S V +D ++K +Y + E
Sbjct: 235 QRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAE 286
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 2440 LAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGY 2499
+ Q E+ + + +Y D + L+A L LP + + DYY I P+D+ I ++
Sbjct: 658 MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANK 717
Query: 2500 YKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIV 2553
Y+ +++ D + +F NA Y +S + +D L K R + D V
Sbjct: 718 YQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHV 771
Score = 45.4 bits (106), Expect = 8e-04
Identities = 30/82 (36%), Positives = 35/82 (42%)
Query: 2470 PPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGR 2529
P KK DYY+ I +P+DL IE I Y E DM +FRNA Y S V
Sbjct: 550 PSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYN 609
Query: 2530 DVCRLRKAYYNARHEASAQIDE 2551
D L K R E D+
Sbjct: 610 DAHILEKLLKEKRKELGPLPDD 631
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 85.1 bits (209), Expect = 9e-16
Identities = 48/134 (35%), Positives = 72/134 (53%), Gaps = 4/134 (2%)
Query: 2145 FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYC--LNLDSGM 2202
+R+ G G+ K + AG+ +IEY G V+ R E++++ C +D
Sbjct: 2580 YRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKR--EKFYDGKGIGCYMFRMDDFD 2637
Query: 2203 VIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNV 2262
V+D+ GN ARFINHSC+PNC + V G I ++AL+ + G ELTYDY F +
Sbjct: 2638 VVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDA 2697
Query: 2263 EKQQLCKCGFEKCR 2276
+ C CG ++CR
Sbjct: 2698 SNKLPCNCGAKRCR 2711
Score = 32.3 bits (72), Expect = 7.2
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 1922 EEQTRKKQKPLPEEEEQENNKSFNEAPV--------EIPSPSETPAKPSEPESTLQPVLS 1973
EE+ +K+++ +E E++ ++ E + ++P P TP PS P P S
Sbjct: 364 EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTS 423
Query: 1974 LIPREKKPPRPP 1985
P PP PP
Sbjct: 424 PPPPLCPPPPPP 435
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 84.0 bits (206), Expect = 2e-15
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 18/179 (10%)
Query: 2116 ECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVS 2175
EC+ + C C C N+ +Q + L+ +R + GWG+R+ + + G F+ EY+GE++S
Sbjct: 1104 ECN-HACSCWRNCRNRVVQNGLRAR-LQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELIS 1161
Query: 2176 EQEFRNRMIEQYHNHSDHYCLNLDS--GMV--IDSYRMGNEARFINHSCDPNCEMQKWSV 2231
+ E R D Y +LD+ G V ID+ GN +RFINH C+PN + +
Sbjct: 1162 DSEADVR-------EEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFM 1214
Query: 2232 N----GVYRIGLYALKDMPAGTELTYDYNFHSFNVE-KQQLCKCGFEKCRGIIGGKSQR 2285
RI ++ + + AG +L +DY ++++ K C+CG KCR +QR
Sbjct: 1215 AHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQR 1273
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 82.0 bits (201), Expect = 8e-15
Identities = 38/72 (52%), Positives = 48/72 (66%), Gaps = 3/72 (4%)
Query: 2562 SSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSD--VEHYL 2619
SS T++S E+G DV RCICG D+G MI CDKC VWQH DCMG++ + YL
Sbjct: 101 SSATTISTSEDG-SYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYL 159
Query: 2620 CEQCDPRPVDRE 2631
CE+C PR +D+E
Sbjct: 160 CERCQPRNLDKE 171
Score = 62.8 bits (151), Expect = 5e-09
Identities = 48/206 (23%), Positives = 93/206 (45%), Gaps = 6/206 (2%)
Query: 2154 IRTKEPLKAGQFIIEYLGEVVSEQEFRNR--MIEQYHNHSDHYCLNLDSGMVIDSYRMGN 2211
+++ + L IIEY G+ + ++F ++ + Y M +D+ GN
Sbjct: 343 LKSAKDLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGN 402
Query: 2212 EARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCG 2271
EARFI SC PN E++ +G + +Y++ +P GTE+T ++F N + + C C
Sbjct: 403 EARFIRRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACL 462
Query: 2272 FE--KCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPS 2329
E +C ++ S+ + + S ++ K SKEK + + +
Sbjct: 463 KENPEC-PVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMK 521
Query: 2330 ENINTPTRLTPQLQMKPMSNRERNFV 2355
+L+P L++ +N+E +F+
Sbjct: 522 SPETKQRKLSP-LRLSVSNNQEPDFI 546
Score = 35.8 bits (81), Expect = 0.65
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 23/145 (15%)
Query: 1654 ERAVQ-TLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDD 1712
ER+ Q L S DK S S +CSP+ +SS S S+ + P+L A G
Sbjct: 1263 ERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHI-------PQLQAKGPV 1315
Query: 1713 SVDSLLQRMVQNEDQEPME----KSIDAVIATASAPPSSS---------PGRSHSKDRTL 1759
S L E+ EP S D T +PP S P ++H K T
Sbjct: 1316 PSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFT- 1374
Query: 1760 GKPDSLLVPAVTSDSCNNSISLLSE 1784
KPD V++ N + L +E
Sbjct: 1375 -KPDPQWDSTVSASEAENGVHLKTE 1398
Score = 33.5 bits (75), Expect = 3.2
Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 19/105 (18%)
Query: 1367 HSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSY 1426
H L P G P + P P P T GL ++ PPPP P PP S
Sbjct: 1675 HHLPPPPPPPGPAPHHHPP--PHPSTGLQ-GLQAQHQHVVNSAPPPPPPP-----PPSSV 1726
Query: 1427 MHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPP 1471
+ +GH + H H+ PL S +P+VPP
Sbjct: 1727 LASGHHTTSAQALHHPPHQ-----------GPPLFPSSAHPTVPP 1760
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 82.0 bits (201), Expect = 8e-15
Identities = 43/129 (33%), Positives = 69/129 (53%), Gaps = 7/129 (5%)
Query: 2152 WGIRTKEPLKAGQFIIEYLGEVVSEQ--EFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRM 2209
WG+ EP+ A + +IEY+G+ + + + R + Q Y +D +ID+ +
Sbjct: 1580 WGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQ-EGIGSSYLFRVDHDTIIDATKC 1638
Query: 2210 GNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQL-C 2268
GN ARFINH C PNC + ++ +I +Y+ + + E+TYDY F +E ++ C
Sbjct: 1639 GNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDY---KFPLEDNKIPC 1695
Query: 2269 KCGFEKCRG 2277
CG E CRG
Sbjct: 1696 LCGTESCRG 1704
Score = 35.4 bits (80), Expect = 0.85
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 1385 PYSPSPLTAAPIGLGYYGRYPPTLYPP----PPSPSFTTPLPPPSYMH 1428
P P P A + LGY P L PP PP P + P PPP +++
Sbjct: 610 PPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIY 657
Score = 32.3 bits (72), Expect = 7.2
Identities = 32/139 (23%), Positives = 47/139 (33%), Gaps = 16/139 (11%)
Query: 794 ADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASK 853
+DSE S S ++ SSS SS S+ + PP R + +P
Sbjct: 1031 SDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPA 1090
Query: 854 VFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPF 913
P+ E+ +P G V+P P++ P R P + PP + P
Sbjct: 1091 ------------PV---EVPVPERVAGSPVTPLPEQEASPARP-AGPTEESPPSAPLRPP 1134
Query: 914 VATESPSKLESESDNHRSS 932
P D SS
Sbjct: 1135 EPPAGPPAPAPRPDERPSS 1153
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 82.0 bits (201), Expect = 8e-15
Identities = 38/72 (52%), Positives = 48/72 (66%), Gaps = 3/72 (4%)
Query: 2562 SSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSD--VEHYL 2619
SS T++S E+G DV RCICG D+G MI CDKC VWQH DCMG++ + YL
Sbjct: 101 SSATTISTSEDG-SYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYL 159
Query: 2620 CEQCDPRPVDRE 2631
CE+C PR +D+E
Sbjct: 160 CERCQPRNLDKE 171
Score = 62.8 bits (151), Expect = 5e-09
Identities = 48/206 (23%), Positives = 93/206 (45%), Gaps = 6/206 (2%)
Query: 2154 IRTKEPLKAGQFIIEYLGEVVSEQEFRNR--MIEQYHNHSDHYCLNLDSGMVIDSYRMGN 2211
+++ + L IIEY G+ + ++F ++ + Y M +D+ GN
Sbjct: 343 LKSAKDLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGN 402
Query: 2212 EARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCG 2271
EARFI SC PN E++ +G + +Y++ +P GTE+T ++F N + + C C
Sbjct: 403 EARFIRRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACL 462
Query: 2272 FE--KCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPS 2329
E +C ++ S+ + + S ++ K SKEK + + +
Sbjct: 463 KENPEC-PVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMK 521
Query: 2330 ENINTPTRLTPQLQMKPMSNRERNFV 2355
+L+P L++ +N+E +F+
Sbjct: 522 SPETKQRKLSP-LRLSVSNNQEPDFI 546
Score = 35.8 bits (81), Expect = 0.65
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 23/145 (15%)
Query: 1654 ERAVQ-TLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDD 1712
ER+ Q L S DK S S +CSP+ +SS S S+ + P+L A G
Sbjct: 1263 ERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHI-------PQLQAKGPV 1315
Query: 1713 SVDSLLQRMVQNEDQEPME----KSIDAVIATASAPPSSS---------PGRSHSKDRTL 1759
S L E+ EP S D T +PP S P ++H K T
Sbjct: 1316 PSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFT- 1374
Query: 1760 GKPDSLLVPAVTSDSCNNSISLLSE 1784
KPD V++ N + L +E
Sbjct: 1375 -KPDPQWDSTVSASEAENGVHLKTE 1398
Score = 33.5 bits (75), Expect = 3.2
Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 19/105 (18%)
Query: 1367 HSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSY 1426
H L P G P + P P P T GL ++ PPPP P PP S
Sbjct: 1675 HHLPPPPPPPGPAPHHHPP--PHPSTGLQ-GLQAQHQHVVNSAPPPPPPP-----PPSSV 1726
Query: 1427 MHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPP 1471
+ +GH + H H+ PL S +P+VPP
Sbjct: 1727 LASGHHTTSAQALHHPPHQ-----------GPPLFPSSAHPTVPP 1760
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 82.0 bits (201), Expect = 8e-15
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 24/183 (13%)
Query: 2642 QPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEK 2701
+PGC YF L +D+ L+ GDCV++ P + RIEK
Sbjct: 1117 EPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPR--------------------VGRIEK 1156
Query: 2702 LWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYT 2761
+W + F +G + P ET H P++ FY E+F L E P+ ++G C VL
Sbjct: 1157 VWVRDGAAYF-YGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKD 1215
Query: 2762 YCKGRPKGVKEQDVYICDYRL---DKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKD 2818
+ RP + E D+ +C+ R DK F + R +F K + P+K+
Sbjct: 1216 FLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKE 1275
Query: 2819 FSP 2821
SP
Sbjct: 1276 PSP 1278
Score = 64.7 bits (156), Expect = 1e-09
Identities = 32/99 (32%), Positives = 50/99 (50%)
Query: 2446 EICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEA 2505
E+ + I YKD + L + P ++ DYYE +S P+DL+ I++++ Y V
Sbjct: 52 ELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNL 111
Query: 2506 FDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
AD +F NA+ YY SP + C+L Y R+E
Sbjct: 112 LTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNE 150
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/129 (25%), Positives = 72/129 (55%)
Query: 2444 FKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTV 2503
F ++ D + S +++ Q +A P +LP KKK DYY++I P+ L I ++ Y+T+
Sbjct: 386 FYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETL 445
Query: 2504 EAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSS 2563
+ + D+ +F NA++Y S + + V +L++ + E + + D G++ + +S
Sbjct: 446 DHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATS 505
Query: 2564 ETSVSEKEN 2572
+T +++++
Sbjct: 506 DTGSAKRKS 514
Score = 58.5 bits (140), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%)
Query: 2433 EVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIE 2492
E + A L +I +++ + I+ + S + ++ LP K + DYY I +P+DL TI
Sbjct: 175 EGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIA 234
Query: 2493 KQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
++I G YK++ A D+ + +NA+ Y S V +D ++K +Y + E
Sbjct: 235 QRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAE 286
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 2440 LAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGY 2499
+ Q E+ + + +Y D + L+A L LP + + DYY I P+D+ I ++
Sbjct: 658 MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANK 717
Query: 2500 YKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIV 2553
Y+ +++ D + +F NA Y +S + +D L K R + D V
Sbjct: 718 YQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHV 771
Score = 45.4 bits (106), Expect = 8e-04
Identities = 30/82 (36%), Positives = 35/82 (42%)
Query: 2470 PPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGR 2529
P KK DYY+ I +P+DL IE I Y E DM +FRNA Y S V
Sbjct: 550 PSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYN 609
Query: 2530 DVCRLRKAYYNARHEASAQIDE 2551
D L K R E D+
Sbjct: 610 DAHILEKLLKEKRKELGPLPDD 631
Score = 42.0 bits (97), Expect = 0.009
Identities = 18/65 (27%), Positives = 34/65 (52%)
Query: 2735 ELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHR 2794
E+F+ Y +P+ ++G C V+ + Y K P+ +++DV++C+ R F KI
Sbjct: 991 EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKL 1050
Query: 2795 NRYPV 2799
P+
Sbjct: 1051 WTMPI 1055
>gi|194294556 SET binding protein 1 isoform b [Homo sapiens]
Length = 242
Score = 77.8 bits (190), Expect = 1e-13
Identities = 58/156 (37%), Positives = 79/156 (50%), Gaps = 23/156 (14%)
Query: 40 EKNTKEEEDLRKRNRERNIEAGKD-------DGLTDAQQQFSVKETNFSEGNLKLKIGLQ 92
E+ EEED R+ + + D DGL + Q+FS+KE NF+EG+LKLKI
Sbjct: 53 ERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEE--QEFSIKEANFTEGSLKLKIQT- 109
Query: 93 AKRTKKPPKNLENYVCRPAIKTTIKH--PRKALKSGKMTDEKNEHCPSKRDPSKLYKKAD 150
KR KKPPKNLENY+C P IK TIK +K ++GK + E + K A
Sbjct: 110 TKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEE--ERSHSKKKLLTAS 167
Query: 151 DVAA---------IECQSEEVIRLHSQGENNPLSKK 177
D+AA I+ S+E + G+ P K+
Sbjct: 168 DLAASDLKGFQPQIKDSSKEEVWKRRGGQGIPFKKQ 203
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 77.4 bits (189), Expect = 2e-13
Identities = 45/143 (31%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Query: 2135 RHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDH- 2193
R EW + R+ +G G+ + L+ +IEY+G ++ E NR + Y +
Sbjct: 5392 RTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTII-RNEVANRREKIYEEQNRGI 5450
Query: 2194 YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTY 2253
Y +++ VID+ G AR+INHSC PNC + + + +I + + + +P G ELTY
Sbjct: 5451 YMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTY 5510
Query: 2254 DYNFHSFNVEKQQLCKCGFEKCR 2276
DY F + + + C CG CR
Sbjct: 5511 DYQFDFEDDQHKIPCHCGAWNCR 5533
Score = 36.6 bits (83), Expect = 0.38
Identities = 99/447 (22%), Positives = 147/447 (32%), Gaps = 83/447 (18%)
Query: 1561 PSESSPLALGLQTPLQI--DCSESSPSLSLGGFTPNSEPASSD---EHTNLFTSAIGSCR 1615
P E SP + L+TPL + S SP +P E + E + L S
Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM 581
Query: 1616 VSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPS 1675
P S ++ LF + S +ES S L S P D P P
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL--SPPPEDSPMSPPP 639
Query: 1676 ESTNCSPTRK--RSSSESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKS 1733
E + SP + R S S ++ P SP L ++S S E S
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESP-LSPPPEESPTS--------PPPEASRLS 690
Query: 1734 IDAVIATASAPPSSSPGRSHSKDRTLGKP--DSLLVPAVTSDSCNNSISLLSEKLTSSCS 1791
+ S PP SP +D + P +S L+P + S
Sbjct: 691 PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP----------QLCPRSEG 740
Query: 1792 PHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPG 1851
PH L+ + H++ + L QA + + +P
Sbjct: 741 PH-----------------------LSPRPEEPHLSPRPEEPHLSPQAEEPH--LSPQPE 775
Query: 1852 RPRKCPLQAVVSMQAFQAAQFVNPELNRDEEGAALHLSPDTVTDVIEAVVQSVNLNPEHK 1911
P C V + + Q P L+ E LHLSP T + V + L+P+ +
Sbjct: 776 EPCLC----AVPEEPHLSPQAEGPHLSPQPE--ELHLSPQTEEPHLSPVPEEPCLSPQPE 829
Query: 1912 KG-------------LKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETP 1958
+ + L E + P PE+ +E P + P+P E P
Sbjct: 830 ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE--------PGQCPAPEELP 881
Query: 1959 AKPSEPESTLQPVLSLIPREKKPPRPP 1985
P E +L P+L P +P PP
Sbjct: 882 LFPPPGEPSLSPLLG-EPALSEPGEPP 907
Score = 35.8 bits (81), Expect = 0.65
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 2588 YKDEGLMIQCDKCMVWQH--CDCMGVNSDVEH-----YLCEQCDPRPVDREVPMIP 2636
Y +E L+IQC C W H C+ + DVE + C C P V P+ P
Sbjct: 1514 YVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYVVKPVAPVAP 1569
Score = 35.4 bits (80), Expect = 0.85
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 1344 PDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGR 1403
P + R PP + +P LS PL + P P SPL+ P +
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSP----PPEESPLSPPPESSPFSPL 515
Query: 1404 YPPTLYPP---PPSPSFTTPLPPP 1424
L PP PPSP+ TPL PP
Sbjct: 516 EESPLSPPEESPPSPALETPLSPP 539
Score = 34.3 bits (77), Expect = 1.9
Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 11/102 (10%)
Query: 1337 PLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGM--PYSPSPLTAA 1394
P +++R P G P MR + SL P+ G P +G+ + P P
Sbjct: 2515 PPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGK 2574
Query: 1395 PIGLGY---YGRYPPTLYPPPPSPSFT------TPLPPPSYM 1427
P Y G + P+ P PS T +PL PPS +
Sbjct: 2575 PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616
Score = 33.5 bits (75), Expect = 3.2
Identities = 35/153 (22%), Positives = 57/153 (37%), Gaps = 20/153 (13%)
Query: 1850 PGRPRKCPLQAVVSMQAFQAAQFVNP---ELNRDEEGAALHLSPDTVTDVIEAVVQSVNL 1906
P P+ CP + ++P E + + HLSP + AV + +L
Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 1907 NPE----HKKGLKRKGWLLEEQTRKKQKPLPEE-----EEQENNKSFNEAPVEIPSPSET 1957
+P+ H + L + P+PEE + +E++ S P E
Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS--------PQSEEP 840
Query: 1958 PAKPSEPESTLQPVLSLIPREKKPPRPPKKKYQ 1990
P ES L P L P +P +PP++ Q
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Score = 32.3 bits (72), Expect = 7.2
Identities = 49/189 (25%), Positives = 63/189 (33%), Gaps = 28/189 (14%)
Query: 1393 AAPIGLGYYGRY--PPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPAK---YHKKKHKLL 1447
A P G YY + L PP PS P PPPS + P++ H K
Sbjct: 4599 ALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASA 4658
Query: 1448 R--QEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTG 1505
R + A TS L + PP H + S+ P +
Sbjct: 4659 RDSERALRDTSEVKSLDLLAALPTPP---------HNQTEDVRMESDEDSDSPDSIVPAS 4709
Query: 1506 SSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESS 1565
S S+L G++A R+ H R LSP LI R V P
Sbjct: 4710 SPESIL--------GEEA--PRFPHLGSGRWEQEDRALSPVIPLIPRASIPVF--PDTKP 4757
Query: 1566 PLALGLQTP 1574
ALGL+ P
Sbjct: 4758 YGALGLEVP 4766
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,147,773
Number of Sequences: 37866
Number of extensions: 6559663
Number of successful extensions: 33444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 28053
Number of HSP's gapped (non-prelim): 5652
length of query: 2964
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2844
effective length of database: 13,703,598
effective search space: 38973032712
effective search space used: 38973032712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.