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Search of human proteins with 110347453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
(635 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347453 solute carrier family 7 (cationic amino acid transp... 1254 0.0
gi|114326550 solute carrier family 7 (cationic amino acid transp... 477 e-134
gi|114326544 solute carrier family 7 (cationic amino acid transp... 477 e-134
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 468 e-131
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 465 e-131
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 461 e-129
gi|181337167 solute carrier family 7 (cationic amino acid transp... 412 e-115
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 125 9e-29
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 125 9e-29
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 108 1e-23
gi|115648063 solute carrier family 7 (cationic amino acid transp... 105 1e-22
gi|115648022 solute carrier family 7 (cationic amino acid transp... 105 1e-22
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 103 5e-22
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 101 2e-21
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 101 2e-21
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 101 2e-21
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 96 8e-20
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 95 2e-19
gi|71999149 solute carrier family 7, (cationic amino acid transp... 72 1e-12
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 41 0.004
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 39 0.019
gi|123701900 solute carrier family 12 (potassium/chloride transp... 37 0.072
gi|198041678 solute carrier family 12 (potassium-chloride transp... 34 0.36
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 34 0.36
gi|54112388 formyl peptide receptor-like 1 [Homo sapiens] 33 0.80
gi|4503781 formyl peptide receptor-like 1 [Homo sapiens] 33 0.80
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 33 1.0
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 33 1.0
gi|239735603 POM121 membrane glycoprotein-like 12 [Homo sapiens] 32 2.3
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 32 2.3
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 1254 bits (3246), Expect = 0.0
Identities = 635/635 (100%), Positives = 635/635 (100%)
Query: 1 MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTG 60
MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTG
Sbjct: 1 MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTG 60
Query: 61 AVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW 120
AVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW
Sbjct: 61 AVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW 120
Query: 121 NVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLA 180
NVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLA
Sbjct: 121 NVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLA 180
Query: 181 SAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAG 240
SAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAG
Sbjct: 181 SAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAG 240
Query: 241 TASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLD 300
TASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLD
Sbjct: 241 TASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLD 300
Query: 301 PDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHV 360
PDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHV
Sbjct: 301 PDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHV 360
Query: 361 HPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPP 420
HPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPP
Sbjct: 361 HPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPP 420
Query: 421 SSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSPGAVVTW 480
SSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSPGAVVTW
Sbjct: 421 SSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSPGAVVTW 480
Query: 481 ALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLF 540
ALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLF
Sbjct: 481 ALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLF 540
Query: 541 QIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQRELPGL 600
QIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQRELPGL
Sbjct: 541 QIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQRELPGL 600
Query: 601 NSTHYVVFPRGSLEETVQAMQPPSQAPAQDPGHME 635
NSTHYVVFPRGSLEETVQAMQPPSQAPAQDPGHME
Sbjct: 601 NSTHYVVFPRGSLEETVQAMQPPSQAPAQDPGHME 635
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 477 bits (1227), Expect = e-134
Identities = 261/613 (42%), Positives = 374/613 (61%), Gaps = 62/613 (10%)
Query: 13 RLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVL 72
R QKL R + LE ET L RCLSTLDL LGVG +G+G+YVL G VAK+ AGP+++
Sbjct: 8 RFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIV 67
Query: 73 LSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAA 132
+ F VAA++S+LA LCYAEFGARVPR+GSAYL++YV++GELWAF GWN++L Y+IG A+
Sbjct: 68 ICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTAS 127
Query: 133 VARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSS 192
VARAWS D++ + I + + +L YPDF A G++LL + ++ GA S+
Sbjct: 128 VARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESA 187
Query: 193 WLNHTFSAISLLVILFIVILGFILAQPHNWSADE---------------------GGFAP 231
+ F+ ++LLV+ F++I GF+ HNW E GGF P
Sbjct: 188 LVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVP 247
Query: 232 FGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLT 291
FGF G++ G A+CFYAFVGFD IA + EEAQNP+RS+P+ I ISL++ AY VS+ LT
Sbjct: 248 FGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALT 307
Query: 292 LMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADG 351
LM+P++ L P+S L +AF G+ A ++VA GS+CA++T LL +F +PR++YAMA DG
Sbjct: 308 LMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDG 367
Query: 352 LFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIV 411
L F+V A +H T+ P+ T+ G++ AF+A L L LV +S+GTLLAY+ V+ +++
Sbjct: 368 LLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLI 427
Query: 412 LRFQKSSPPSSPGPASPGPLTKQQ-SSFSDHLQLVGTVHA--SVPEPGELKPALRPYLGF 468
LR+Q P L ++ ++ S+ L L G S+P P
Sbjct: 428 LRYQ---PDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTP------------- 471
Query: 469 LDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILL---LLLTSVMFLLSL 525
L G + + +LA +T C++ L W LL LL T+V+ LL L
Sbjct: 472 LSGQ-----IVYVCSSLLAVLLTALCLV--------LAQWSVPLLSGDLLWTAVVVLLLL 518
Query: 526 LVLGA-----HQQQYREDL-FQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGL 579
L++G Q Q L F++P +PL+P +SI +NI LM++++ TW RF +W+L+G
Sbjct: 519 LIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGF 578
Query: 580 AVYFGYGIRHSKE 592
A+YFGYGI+HS E
Sbjct: 579 AIYFGYGIQHSLE 591
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 477 bits (1227), Expect = e-134
Identities = 261/613 (42%), Positives = 374/613 (61%), Gaps = 62/613 (10%)
Query: 13 RLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVL 72
R QKL R + LE ET L RCLSTLDL LGVG +G+G+YVL G VAK+ AGP+++
Sbjct: 8 RFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIV 67
Query: 73 LSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAA 132
+ F VAA++S+LA LCYAEFGARVPR+GSAYL++YV++GELWAF GWN++L Y+IG A+
Sbjct: 68 ICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTAS 127
Query: 133 VARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSS 192
VARAWS D++ + I + + +L YPDF A G++LL + ++ GA S+
Sbjct: 128 VARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESA 187
Query: 193 WLNHTFSAISLLVILFIVILGFILAQPHNWSADE---------------------GGFAP 231
+ F+ ++LLV+ F++I GF+ HNW E GGF P
Sbjct: 188 LVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVP 247
Query: 232 FGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLT 291
FGF G++ G A+CFYAFVGFD IA + EEAQNP+RS+P+ I ISL++ AY VS+ LT
Sbjct: 248 FGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALT 307
Query: 292 LMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADG 351
LM+P++ L P+S L +AF G+ A ++VA GS+CA++T LL +F +PR++YAMA DG
Sbjct: 308 LMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDG 367
Query: 352 LFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIV 411
L F+V A +H T+ P+ T+ G++ AF+A L L LV +S+GTLLAY+ V+ +++
Sbjct: 368 LLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLI 427
Query: 412 LRFQKSSPPSSPGPASPGPLTKQQ-SSFSDHLQLVGTVHA--SVPEPGELKPALRPYLGF 468
LR+Q P L ++ ++ S+ L L G S+P P
Sbjct: 428 LRYQ---PDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTP------------- 471
Query: 469 LDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILL---LLLTSVMFLLSL 525
L G + + +LA +T C++ L W LL LL T+V+ LL L
Sbjct: 472 LSGQ-----IVYVCSSLLAVLLTALCLV--------LAQWSVPLLSGDLLWTAVVVLLLL 518
Query: 526 LVLGA-----HQQQYREDL-FQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGL 579
L++G Q Q L F++P +PL+P +SI +NI LM++++ TW RF +W+L+G
Sbjct: 519 LIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGF 578
Query: 580 AVYFGYGIRHSKE 592
A+YFGYGI+HS E
Sbjct: 579 AIYFGYGIQHSLE 591
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 468 bits (1203), Expect = e-131
Identities = 250/600 (41%), Positives = 370/600 (61%), Gaps = 47/600 (7%)
Query: 26 DSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLA 85
DS +T L RCLST+DL LGVG +G+G+YVL G VAK +GP++++SF +AA+AS++A
Sbjct: 23 DSLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMA 82
Query: 86 ALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMF 145
LCYAEFGARVP+TGSAYL+TYV++GELWAF+ GWN++L Y+IG ++VARAWSG D +
Sbjct: 83 GLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELL 142
Query: 146 SHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLV 205
S I F T+ L YPDF A +ILL + +S G + S+W+N F+A+++LV
Sbjct: 143 SKQIGQFLRTYF-RMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILV 201
Query: 206 ILFIVILGFILAQPHNWSADE------------------------GGFAPFGFSGVMAGT 241
+LF+++ GF+ NW E GGF P+GF+G +AG
Sbjct: 202 LLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 261
Query: 242 ASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDP 301
A+CFYAFVGFD IA + EE +NP++++P+ I SL + AY VS LTLM+P++ LD
Sbjct: 262 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 321
Query: 302 DSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVH 361
S L AF G+ A ++VAAGS+CA++T LL +F +PR++YAMA DGL F+ A ++
Sbjct: 322 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQIN 381
Query: 362 PRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ------ 415
+T+ P+ TL+ G + A +A L DL++LV +S+GTL+AY+ VA +++LR+Q
Sbjct: 382 SKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLSYD 441
Query: 416 --KSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYS 473
K SP +SP +K +S + LQ G ++ P L L
Sbjct: 442 QPKCSPEKDGLGSSPRVTSKSESQVT-MLQRQGF---------SMRTLFCPSL--LPTQQ 489
Query: 474 PGAVVTWALGVMLASAITIGCVLVFG-NSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQ 532
++V++ +G + + + + +G ++ L W + LL L V+F+ +L +
Sbjct: 490 SASLVSFLVGFLAFLVLGLSVLTTYGVHAITRLEAWS-LALLALFLVLFVAIVLTIWRLP 548
Query: 533 QQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKE 592
Q ++ F +P +P +PA SI++NI LM++LS TWVRFSIW+ +G +YF YGIRHS E
Sbjct: 549 QNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGIRHSLE 608
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 465 bits (1196), Expect = e-131
Identities = 255/600 (42%), Positives = 370/600 (61%), Gaps = 48/600 (8%)
Query: 26 DSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLA 85
DS +T L RCLST+DL LGVG +G+G+YVL G VAK +GP++++SF +AA+AS++A
Sbjct: 63 DSLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMA 122
Query: 86 ALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMF 145
LCYAEFGARVP+TGSAYL+TYV++GELWAF+ GWN++L Y+IG ++VARAWSG D +
Sbjct: 123 GLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELL 182
Query: 146 SHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLV 205
S I F T+ L YPDF A +ILL + +S G + S+W+N F+A+++LV
Sbjct: 183 SKQIGQFLRTYF-RMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILV 241
Query: 206 ILFIVILGFILAQPHNWSADE------------------------GGFAPFGFSGVMAGT 241
+LF+++ GF+ NW E GGF P+GF+G +AG
Sbjct: 242 LLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 301
Query: 242 ASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDP 301
A+CFYAFVGFD IA + EE +NP++++P+ I SL + AY VS LTLM+P++ LD
Sbjct: 302 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 361
Query: 302 DSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVH 361
S L AF G+ A ++VAAGS+CA++T LL +F LPRI++AMA DGL F+ A V
Sbjct: 362 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS 421
Query: 362 PRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ------ 415
R Q PVA TL G+++A +A L DL++LV +S+GTL+AY+ VA +++LR+Q
Sbjct: 422 KR-QSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLSYD 480
Query: 416 --KSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYS 473
K SP +SP +K +S + LQ G ++ P L L
Sbjct: 481 QPKCSPEKDGLGSSPRVTSKSESQVT-MLQRQGF---------SMRTLFCPSL--LPTQQ 528
Query: 474 PGAVVTWALGVMLASAITIGCVLVFG-NSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQ 532
++V++ +G + + + + +G ++ L W + LL L V+F+ +L +
Sbjct: 529 SASLVSFLVGFLAFLVLGLSVLTTYGVHAITRLEAWS-LALLALFLVLFVAIVLTIWRLP 587
Query: 533 QQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKE 592
Q ++ F +P +P +PA SI++NI LM++LS TWVRFSIW+ +G +YF YGIRHS E
Sbjct: 588 QNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGIRHSLE 647
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 461 bits (1185), Expect = e-129
Identities = 251/610 (41%), Positives = 365/610 (59%), Gaps = 33/610 (5%)
Query: 11 LARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPA 70
L + Q++ R K ++ S ET L RCL+T DL LGVG +G+G+YVL GAVA+E AGPA
Sbjct: 6 LLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPA 65
Query: 71 VLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGG 130
+++SF +AA+AS+LA LCY EFGARVP+TGSAYL++YV++GELWAF+ GWN++L YIIG
Sbjct: 66 IVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGT 125
Query: 131 AAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARV 190
++VARAWS D + I F+ TH+ +L PD A IIL+ + ++ G +
Sbjct: 126 SSVARAWSATFDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKE 185
Query: 191 SSWLNHTFSAISLLVILFIVILGFILAQPHNWSADE-----------------------G 227
S+ +N F+ I++LV+ FI++ GF+ NW E G
Sbjct: 186 SAMVNKIFTCINVLVLGFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVG 245
Query: 228 GFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVS 287
GF PFGFSGV++G A+CFYAFVGFD IA + EE +NP++++P+ I SL I AY VS
Sbjct: 246 GFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVS 305
Query: 288 TVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAM 347
LTLM+P+ LD +S L DAF G+ A + VA GS+CA++ LL +F +PR++YAM
Sbjct: 306 AALTLMMPYFCLDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAM 365
Query: 348 AADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVAT 407
A DGL F+ A+V+ RT+ P+ TLA G + A +A L DL+ LV +S+GTLLAY+ VA
Sbjct: 366 AEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAA 425
Query: 408 SIIVLRFQKSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASV-----PEPGELKPAL 462
++VLR+Q P P T + +D +L T + + E LK L
Sbjct: 426 CVLVLRYQ----PEQPNLVYQMASTSDELDPADQNELASTNDSQLGFLPEAEMFSLKTIL 481
Query: 463 RPYLGFLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFL 522
P G +V + ++ IT V V G L + LL ++++
Sbjct: 482 SP-KNMEPSKISGLIVNISTSLIAVLIITFCIVTVLGREALTKGALWAVFLLAGSALLCA 540
Query: 523 LSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVY 582
+ V+ + + F++P +P++P LSI +N+ LM++L TWVRF++W+L+G +Y
Sbjct: 541 VVTGVIWRQPESKTKLSFKVPFLPVLPILSIFVNVYLMMQLDQGTWVRFAVWMLIGFIIY 600
Query: 583 FGYGIRHSKE 592
FGYG+ HS+E
Sbjct: 601 FGYGLWHSEE 610
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 412 bits (1060), Expect = e-115
Identities = 245/655 (37%), Positives = 363/655 (55%), Gaps = 83/655 (12%)
Query: 17 KLNRLKPLED--------STMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAG 68
++ R KP+E + T L + L+T+DL LGVG VG+G+YV++G VAKE+AG
Sbjct: 25 RILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAG 84
Query: 69 PAVLLSFGVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGELWAFLIGWNVLLEYI 127
P V++SF +AAVAS+L+ +CYAEFG RVP+T GSAY ++YV++GE AF IGWN++LEY+
Sbjct: 85 PGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYL 144
Query: 128 IGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGH--YPDFLAAGIILLASAFVS 185
IG AA A A S DS+ +H+I + VG+ G YPD LA I ++ + V+
Sbjct: 145 IGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVA 204
Query: 186 CGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCF 245
G + S N+ + ++L V +FI+I G W+ EG F P G+SGV+ G A+CF
Sbjct: 205 LGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWA--EGQFLPHGWSGVLQGAATCF 262
Query: 246 YAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSAL 305
YAF+GFD+IA + EEA+NP S+P AI SL I AY+ VS +LTLMVP++++D +S L
Sbjct: 263 YAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPL 322
Query: 306 ADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQ 365
+ F G+ A F+VA GS+ + LL LF +PR++YAMA DGL F+ AHV T+
Sbjct: 323 MEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTE 382
Query: 366 VPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS------- 418
PV + G L A LALL+ L L++ +S+GTLLAYT V+ +++LR+Q S
Sbjct: 383 TPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVK 442
Query: 419 ----------------------PPSSPGPASPGPLT-----KQQSSFSDHLQLVG----- 446
P S G GP T K S D+ L+G
Sbjct: 443 FLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSDKS 502
Query: 447 TVHASVPEPG-------------------ELKPALRPYL----------GFLD--GYSPG 475
T + + P G +LK + P+ G +D + G
Sbjct: 503 TYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAATG 562
Query: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
VT + ++ ++FG+ + W ILL++L ++ + V+ +
Sbjct: 563 HTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENP 622
Query: 536 REDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHS 590
++ + P +P +PA ++++NI LMLKLS +TW+RF++W +GL +YFGYGI +S
Sbjct: 623 KKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNS 677
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 125 bits (315), Expect = 9e-29
Identities = 99/395 (25%), Positives = 182/395 (46%), Gaps = 27/395 (6%)
Query: 31 TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAK--EVAGPAVLLSFGVAAVASLLAALC 88
TSL++ L + + VG ++GSG++V +V E GP +++ + V + L ALC
Sbjct: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGYLDSMFSH 147
+AE G + ++G Y + + G + A+L W ++++ A + ++S Y+ + F
Sbjct: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPF-- 140
Query: 148 SIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVIL 207
+VG ++ LAA IL S S R+ S++ + F+A L+++
Sbjct: 141 --------YVGCKPPQIV---VKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVA 189
Query: 208 FIVILGFILAQPHNWSADEGGF--APFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPR 265
I+I G +L N + F A + + +A+ G++ + +EE +NP
Sbjct: 190 IIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPY 249
Query: 266 RSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV---- 321
R++PLAI I + + YIL++ ++ L A+A F R A +IV
Sbjct: 250 RNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFV 309
Query: 322 AAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFL 381
A +I A N F+ R++Y +G +V +++ R P + +G++
Sbjct: 310 AFSTIGAAN----GTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIY 365
Query: 382 ALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
+ D+ SLV + S L Y +IV+RF +
Sbjct: 366 IIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTR 400
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 125 bits (315), Expect = 9e-29
Identities = 99/395 (25%), Positives = 182/395 (46%), Gaps = 27/395 (6%)
Query: 31 TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAK--EVAGPAVLLSFGVAAVASLLAALC 88
TSL++ L + + VG ++GSG++V +V E GP +++ + V + L ALC
Sbjct: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGYLDSMFSH 147
+AE G + ++G Y + + G + A+L W ++++ A + ++S Y+ + F
Sbjct: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPF-- 140
Query: 148 SIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVIL 207
+VG ++ LAA IL S S R+ S++ + F+A L+++
Sbjct: 141 --------YVGCKPPQIV---VKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVA 189
Query: 208 FIVILGFILAQPHNWSADEGGF--APFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPR 265
I+I G +L N + F A + + +A+ G++ + +EE +NP
Sbjct: 190 IIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPY 249
Query: 266 RSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV---- 321
R++PLAI I + + YIL++ ++ L A+A F R A +IV
Sbjct: 250 RNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFV 309
Query: 322 AAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFL 381
A +I A N F+ R++Y +G +V +++ R P + +G++
Sbjct: 310 AFSTIGAAN----GTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIY 365
Query: 382 ALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
+ D+ SLV + S L Y +IV+RF +
Sbjct: 366 IIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTR 400
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 108 bits (271), Expect = 1e-23
Identities = 98/394 (24%), Positives = 175/394 (44%), Gaps = 25/394 (6%)
Query: 32 SLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVASLLAALCYA 90
+L+R ++ L+ + VG ++GSG++V V KE P + L+ + V S++ ALCYA
Sbjct: 45 TLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYA 104
Query: 91 EFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMF--SHS 148
E G + ++G Y + G L AFL W LL + R S Y+ ++ ++
Sbjct: 105 ELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYL 156
Query: 149 IRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILF 208
++ T P+ +A +LL +A + ++ + F+A LL +
Sbjct: 157 LKPLFPT------CPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
Query: 209 IVILGFILAQPHNWSADEGGFAPFG----FSGVMAGTASCFYAFVGFDVIAASSEEAQNP 264
I++LGF+ + S + F+ G ++ S +A+ G++ + +EE NP
Sbjct: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270
Query: 265 RRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAF--YQRGYRWAGFIVA 322
R++PLAI ISL I Y+L + + + A+A F Y G V
Sbjct: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330
Query: 323 AGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLA 382
G C + + LF+ R+ + + +G + + +HP+ PV + ++T A
Sbjct: 331 VGLSCFGS--VNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYA 388
Query: 383 LLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
D+ S++ F S L +I LR +K
Sbjct: 389 FSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRK 422
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 105 bits (263), Expect = 1e-22
Identities = 98/413 (23%), Positives = 186/413 (45%), Gaps = 32/413 (7%)
Query: 23 PLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVA 81
P + S+ L++ +S L+ L VG M+GSG++V V A + L+ + + +
Sbjct: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
Query: 82 SLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGY 140
S++ ALCYAE G + ++G++Y + + G AF+ W ++L+ G A +A ++ Y
Sbjct: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
Query: 141 LDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLAS----AFVSCGARVSSWLNH 196
+ + S P L LAA I L + A+V G RV
Sbjct: 151 I-----------IQPSFPSCDPPYLACR--LLAAACICLLTFVNCAYVKWGTRVQD---- 193
Query: 197 TFSAISLLVILFIVILGFI-LAQPHN---WSADEGGFAPFGFSGVMAGTASCFYAFVGFD 252
TF+ ++ ++ I+++G + L Q H+ A EG G + S +++ G+D
Sbjct: 194 TFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMG--NLSLALYSALFSYSGWD 251
Query: 253 VIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR 312
+ +EE +NP R++PLAI IS+ I YIL + ++ + A+A F +
Sbjct: 252 TLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQ 311
Query: 313 GYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTL 372
+ + + + L + +F+ R+ + + +G + + +H P+ L
Sbjct: 312 TFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIP-AL 370
Query: 373 AFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
F A + L+ +E + Q ++ + + FV S++ + + P P P
Sbjct: 371 LFNCTMALIYLI--VEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRP 421
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 105 bits (263), Expect = 1e-22
Identities = 98/413 (23%), Positives = 186/413 (45%), Gaps = 32/413 (7%)
Query: 23 PLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVA 81
P + S+ L++ +S L+ L VG M+GSG++V V A + L+ + + +
Sbjct: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
Query: 82 SLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGY 140
S++ ALCYAE G + ++G++Y + + G AF+ W ++L+ G A +A ++ Y
Sbjct: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
Query: 141 LDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLAS----AFVSCGARVSSWLNH 196
+ + S P L LAA I L + A+V G RV
Sbjct: 151 I-----------IQPSFPSCDPPYLACR--LLAAACICLLTFVNCAYVKWGTRVQD---- 193
Query: 197 TFSAISLLVILFIVILGFI-LAQPHN---WSADEGGFAPFGFSGVMAGTASCFYAFVGFD 252
TF+ ++ ++ I+++G + L Q H+ A EG G + S +++ G+D
Sbjct: 194 TFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMG--NLSLALYSALFSYSGWD 251
Query: 253 VIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR 312
+ +EE +NP R++PLAI IS+ I YIL + ++ + A+A F +
Sbjct: 252 TLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQ 311
Query: 313 GYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTL 372
+ + + + L + +F+ R+ + + +G + + +H P+ L
Sbjct: 312 TFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIP-AL 370
Query: 373 AFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
F A + L+ +E + Q ++ + + FV S++ + + P P P
Sbjct: 371 LFNCTMALIYLI--VEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRP 421
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 103 bits (257), Expect = 5e-22
Identities = 99/396 (25%), Positives = 178/396 (44%), Gaps = 29/396 (7%)
Query: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLS-FGVAAVASLLAALC 88
+ L+R ++ L + +G ++G+G+++ V + + L+ + V V SL AL
Sbjct: 37 KVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALS 96
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVA---RAWSGYLDSMF 145
YAE G + ++G Y + G L AF+ W LL II AA A A+ Y+ F
Sbjct: 97 YAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATAVISLAFGRYILEPF 154
Query: 146 SHSIRNFTETHVGSWQVPLLGHYPDFLAAGI---ILLASAFVSCGARVSSWLNHTFSAIS 202
F + + + L+ A GI ++L S VS AR+ +L TF ++
Sbjct: 155 ------FIQCEIPELAIKLI------TAVGITVVMVLNSMSVSWSARIQIFL--TFCKLT 200
Query: 203 LLVILFIV-ILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEA 261
++I+ + ++ I Q N+ G + + YA+ G+ + +EE
Sbjct: 201 AILIIIVPGVMQLIKGQTQNFKDAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEV 259
Query: 262 QNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV 321
+NP +++PLAI IS+AI Y+L + + L +A+A F +R F +
Sbjct: 260 ENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSER--LLGNFSL 317
Query: 322 AAGSICAMNTV--LLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379
A A++ + +F++ R+ Y + +G ++ + +H R P+ + LT
Sbjct: 318 AVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTM 377
Query: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ 415
+ DL+SL+ FLS L +I LR++
Sbjct: 378 IMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYK 413
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 101 bits (252), Expect = 2e-21
Identities = 90/406 (22%), Positives = 177/406 (43%), Gaps = 32/406 (7%)
Query: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLT-GAVAKEVAGPAVLLSFGVAAVASLLAALC 88
+ L++ +S L+ L VG M+GSG++V G + + L+ + V + S+ ALC
Sbjct: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALC 89
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYII---GGAAVARAWSGYL-DSM 144
YAE G + ++G++Y + + G AF+ W LL II A +A ++ Y+ +
Sbjct: 90 YAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAIIAITFANYMVQPL 147
Query: 145 FSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCG-ARVSSWLNHTFSAISL 203
F + + + LAA I L + F++C + + + F+ +
Sbjct: 148 FPSCFAPYAASRL--------------LAAACICLLT-FINCAYVKWGTLVQDIFTYAKV 192
Query: 204 LVILFIVILGFIL----AQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSE 259
L ++ +++ G + A H ++ EG + F + S +++ G+D + +E
Sbjct: 193 LALIAVIVAGIVRLGQGASTHFENSFEG--SSFAVGDIALALYSALFSYSGWDTLNYVTE 250
Query: 260 EAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGF 319
E +NP R++PL+I IS+ I YIL + ++ + A+A F + + +
Sbjct: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNW 310
Query: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379
I+ + L + + + R+ + + +G +H PV L G++
Sbjct: 311 IIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMAL 370
Query: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
+ D+ L+ + S + FV SI+ + + P P P
Sbjct: 371 IYLCVEDIFQLINYYSFS---YWFFVGLSIVGQLYLRWKEPDRPRP 413
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 101 bits (252), Expect = 2e-21
Identities = 90/406 (22%), Positives = 177/406 (43%), Gaps = 32/406 (7%)
Query: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLT-GAVAKEVAGPAVLLSFGVAAVASLLAALC 88
+ L++ +S L+ L VG M+GSG++V G + + L+ + V + S+ ALC
Sbjct: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALC 89
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYII---GGAAVARAWSGYL-DSM 144
YAE G + ++G++Y + + G AF+ W LL II A +A ++ Y+ +
Sbjct: 90 YAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAIIAITFANYMVQPL 147
Query: 145 FSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCG-ARVSSWLNHTFSAISL 203
F + + + LAA I L + F++C + + + F+ +
Sbjct: 148 FPSCFAPYAASRL--------------LAAACICLLT-FINCAYVKWGTLVQDIFTYAKV 192
Query: 204 LVILFIVILGFIL----AQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSE 259
L ++ +++ G + A H ++ EG + F + S +++ G+D + +E
Sbjct: 193 LALIAVIVAGIVRLGQGASTHFENSFEG--SSFAVGDIALALYSALFSYSGWDTLNYVTE 250
Query: 260 EAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGF 319
E +NP R++PL+I IS+ I YIL + ++ + A+A F + + +
Sbjct: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNW 310
Query: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379
I+ + L + + + R+ + + +G +H PV L G++
Sbjct: 311 IIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMAL 370
Query: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
+ D+ L+ + S + FV SI+ + + P P P
Sbjct: 371 IYLCVEDIFQLINYYSFS---YWFFVGLSIVGQLYLRWKEPDRPRP 413
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 101 bits (252), Expect = 2e-21
Identities = 90/406 (22%), Positives = 177/406 (43%), Gaps = 32/406 (7%)
Query: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLT-GAVAKEVAGPAVLLSFGVAAVASLLAALC 88
+ L++ +S L+ L VG M+GSG++V G + + L+ + V + S+ ALC
Sbjct: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALC 89
Query: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYII---GGAAVARAWSGYL-DSM 144
YAE G + ++G++Y + + G AF+ W LL II A +A ++ Y+ +
Sbjct: 90 YAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAIIAITFANYMVQPL 147
Query: 145 FSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCG-ARVSSWLNHTFSAISL 203
F + + + LAA I L + F++C + + + F+ +
Sbjct: 148 FPSCFAPYAASRL--------------LAAACICLLT-FINCAYVKWGTLVQDIFTYAKV 192
Query: 204 LVILFIVILGFIL----AQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSE 259
L ++ +++ G + A H ++ EG + F + S +++ G+D + +E
Sbjct: 193 LALIAVIVAGIVRLGQGASTHFENSFEG--SSFAVGDIALALYSALFSYSGWDTLNYVTE 250
Query: 260 EAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGF 319
E +NP R++PL+I IS+ I YIL + ++ + A+A F + + +
Sbjct: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNW 310
Query: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379
I+ + L + + + R+ + + +G +H PV L G++
Sbjct: 311 IIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMAL 370
Query: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
+ D+ L+ + S + FV SI+ + + P P P
Sbjct: 371 IYLCVEDIFQLINYYSFS---YWFFVGLSIVGQLYLRWKEPDRPRP 413
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 96.3 bits (238), Expect = 8e-20
Identities = 91/383 (23%), Positives = 163/383 (42%), Gaps = 24/383 (6%)
Query: 47 VGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVASLLAALCYAEFGARVPRTGSAYLF 105
VG ++GSG++V V + + L+ + V +++ ALCYAE G +P++G Y +
Sbjct: 50 VGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSY 109
Query: 106 TYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGY-LDSMFSHSIRNFTETHVGSWQVP 163
G L FL W VL+ Y A +A +S Y L +F +
Sbjct: 110 VKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLR------- 162
Query: 164 LLGHYPDFLAAGIILLASAFVSCGA-RVSSWLNHTFSAISLLVILFIVILGF--ILAQPH 220
L A I LL +V+C + R ++ + F+A LL + I+I+G I +
Sbjct: 163 --------LLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEY 214
Query: 221 NWSADEGGFAPF---GFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLA 277
W + F F V +A+ G++ + +EE +P +++P AI IS+
Sbjct: 215 FWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIP 274
Query: 278 IAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLL 337
+ Y+ + + L +A+A F ++ +I+ + + L
Sbjct: 275 LVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL 334
Query: 338 FSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLG 397
F+ R+ +A A +G V A +H + P+ L + T + + D+ +L+ ++
Sbjct: 335 FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFI 394
Query: 398 TLLAYTFVATSIIVLRFQKSSPP 420
L Y IVLR++K P
Sbjct: 395 NYLFYGVTVAGQIVLRWKKPDIP 417
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 94.7 bits (234), Expect = 2e-19
Identities = 85/393 (21%), Positives = 171/393 (43%), Gaps = 22/393 (5%)
Query: 32 SLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGV-AAVASLLAALCYA 90
+L++ + L + +G ++GSG+++ V + + L V + L +LCYA
Sbjct: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94
Query: 91 EFGARVPRTGSAYLFTYVSMGELWAFLIGWN-VLLEYIIGGAAVARAWSGY-LDSMFSHS 148
E G +P++G Y + G L FL+ W+ VL+ Y A ++ +S Y L +F +
Sbjct: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
Query: 149 IRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILF 208
I T + V L+ ++L + S R ++ + F+ LL +
Sbjct: 155 IPPTTASRV--------------LSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSL 200
Query: 209 IVILGFI-LAQPHNWSADEGGFAPFGFSGVMAGTASCF----YAFVGFDVIAASSEEAQN 263
I+ +G + + Q H F + + A F +AF G++ + +EE +
Sbjct: 201 IIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVD 260
Query: 264 PRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAA 323
R+++P AI IS+ + Y + + L +A+A F ++ + +++
Sbjct: 261 ARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPV 320
Query: 324 GSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLAL 383
+ + LF+ R+ ++ A +G + A +H R P+ L TA + L
Sbjct: 321 SVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIML 380
Query: 384 LLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
+ D +L+ ++S L Y +++LR+++
Sbjct: 381 VGDTYTLINYVSFINYLCYGVTILGLLLLRWRR 413
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 72.4 bits (176), Expect = 1e-12
Identities = 87/356 (24%), Positives = 151/356 (42%), Gaps = 28/356 (7%)
Query: 50 MVGSGLYVLT-GAVAKEVAGPAVLLS-FGVAAVASLLAALCYAEFGARVPRTGSAYLFTY 107
++G+G++V G +A V L + A+ ++ + LC AE P +G+ Y F
Sbjct: 26 IIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGAQYYFLK 85
Query: 108 VSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGH 167
G AFL W L +G VA G + +SI+ F S VP L
Sbjct: 86 RYFGSTVAFLNLWTSLF---LGSGVVA----GQALLLAEYSIQPFFP----SCSVPKLPK 134
Query: 168 YPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFIL---AQPHNWSA 224
LA ++ + S G + +WL S + + ++ FI + G + + N
Sbjct: 135 --KCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKENVER 192
Query: 225 DEGGFAPF--GFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGA 282
+ F S ++ ++A+ G + E + PR ++P I +L +
Sbjct: 193 FQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVV 252
Query: 283 YILVS-TVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLP 341
Y+LV+ + LT++ P L D A+A + R + +I+ ++ + LL +F
Sbjct: 253 YLLVNISYLTVLTPREILSSD-AVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSS 311
Query: 342 RIVYAMAADG----LFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQF 393
R +Y + +G LF + +H P T V + TL G L L L+DL + + F
Sbjct: 312 RPIYLASQEGQLPLLFNTLNSHSSPFTAVLLLVTL--GSLAIILTSLIDLINYIFF 365
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 40.8 bits (94), Expect = 0.004
Identities = 77/311 (24%), Positives = 120/311 (38%), Gaps = 57/311 (18%)
Query: 233 GFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTL 292
G +G+MAG A S E ++P R++PL +++A Y+L+ + +
Sbjct: 277 GCTGIMAG--------------ANMSGELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSF 322
Query: 293 MVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGL 352
L D F++ W +V G + +S L RI++A+A D L
Sbjct: 323 TCDRTLLQEDY----GFFRAISLWPP-LVLIGIYATALSASMSSLIGASRILHALARDDL 377
Query: 353 FFQVF--AHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSII 410
F + A V R P A L L + L L +L +++ L+AY V S +
Sbjct: 378 FGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCL 437
Query: 411 VLRFQKSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLD 470
L + S+P P S FS H L+G + + FL
Sbjct: 438 SLEW-ASAPNFRP----------TFSLFSWHTCLLGVASCLL-------------MMFL- 472
Query: 471 GYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVM--FLLSLLVL 528
SPGA A G +L + + G + WGY+ LL + +LL L V
Sbjct: 473 -ISPGA----AGGSLLLMGLLAALLTARGGPS----SWGYVSQALLFHQVRKYLLRLDVR 523
Query: 529 GAHQQQYREDL 539
H + +R L
Sbjct: 524 KDHVKFWRPQL 534
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 38.5 bits (88), Expect = 0.019
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLF--FQVFAHVHPRTQVPVAGTLAFGLL 377
+++AG A + L+ L S P+I A+ D ++ FQ+FA + + P+ G + L+
Sbjct: 602 LISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLI 661
Query: 378 TAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKS 417
L+ +L + +S L +Y + S+ KS
Sbjct: 662 ALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKS 701
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 36.6 bits (83), Expect = 0.072
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 319 FIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGL--FFQVFAHVHPRTQVPVAGTLAFGL 376
+++ GS + L L PR++ A+A DG+ F QVF H + P L L
Sbjct: 505 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGE-PTWALLLTVL 563
Query: 377 LTAFLALLLDLESLVQFLSLGTLLAYTFV 405
+ L+ L+S+ LS+ L+ Y FV
Sbjct: 564 ICETGILIASLDSVAPILSMFFLMCYLFV 592
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 34.3 bits (77), Expect = 0.36
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 258 SEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR----- 312
S + ++ ++S+P +++A + YI + +V + + L D F +
Sbjct: 444 SGDLRDAQKSIPTGTILAIATTSAVYI------SSVVLFGACIEGVVLRDKFGEAVNGNL 497
Query: 313 ---GYRWAG-FIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGL--FFQVFAHVHPRTQV 366
W +++ GS + L L PR++ A++ DG+ F QVF H +
Sbjct: 498 VVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGE- 556
Query: 367 PVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFV 405
P L + L+ L+ + LS+ L+ Y FV
Sbjct: 557 PTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFV 595
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 34.3 bits (77), Expect = 0.36
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 258 SEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR----- 312
S + ++ ++S+P +++A + YI + +V + + L D F +
Sbjct: 421 SGDLRDAQKSIPTGTILAIATTSAVYI------SSVVLFGACIEGVVLRDKFGEAVNGNL 474
Query: 313 ---GYRWAG-FIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGL--FFQVFAHVHPRTQV 366
W +++ GS + L L PR++ A++ DG+ F QVF H +
Sbjct: 475 VVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGE- 533
Query: 367 PVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFV 405
P L + L+ L+ + LS+ L+ Y FV
Sbjct: 534 PTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFV 572
>gi|54112388 formyl peptide receptor-like 1 [Homo sapiens]
Length = 351
Score = 33.1 bits (74), Expect = 0.80
Identities = 47/192 (24%), Positives = 83/192 (43%), Gaps = 36/192 (18%)
Query: 21 LKPLEDSTMETSLRRCLSTLDLTLLGVG---GMVGSGLYVLTGAVAKEVAGPAVLLSFGV 77
L E+ + E++ L L L +LGV G++G+GL + VAG ++ V
Sbjct: 9 LNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIW-------VAG--FRMTRTV 59
Query: 78 AAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW------NVLLE------ 125
+ L AL F A +P +L ++MGE W F GW +++++
Sbjct: 60 TTICYLNLALADFSFTATLP-----FLIVSMAMGEKWPF--GWFLCKLIHIVVDINLFGS 112
Query: 126 -YIIGGAAVARAWSGYLDSMFSHSIRNFT---ETHVGSWQVPLLGHYPDFLAAGIILLAS 181
++IG A+ R L +++ + R + + VG W + L+ P FL + + +
Sbjct: 113 VFLIGFIALDRCIC-VLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPN 171
Query: 182 AFVSCGARVSSW 193
C +SW
Sbjct: 172 GDTYCTFNFASW 183
>gi|4503781 formyl peptide receptor-like 1 [Homo sapiens]
Length = 351
Score = 33.1 bits (74), Expect = 0.80
Identities = 47/192 (24%), Positives = 83/192 (43%), Gaps = 36/192 (18%)
Query: 21 LKPLEDSTMETSLRRCLSTLDLTLLGVG---GMVGSGLYVLTGAVAKEVAGPAVLLSFGV 77
L E+ + E++ L L L +LGV G++G+GL + VAG ++ V
Sbjct: 9 LNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIW-------VAG--FRMTRTV 59
Query: 78 AAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW------NVLLE------ 125
+ L AL F A +P +L ++MGE W F GW +++++
Sbjct: 60 TTICYLNLALADFSFTATLP-----FLIVSMAMGEKWPF--GWFLCKLIHIVVDINLFGS 112
Query: 126 -YIIGGAAVARAWSGYLDSMFSHSIRNFT---ETHVGSWQVPLLGHYPDFLAAGIILLAS 181
++IG A+ R L +++ + R + + VG W + L+ P FL + + +
Sbjct: 113 VFLIGFIALDRCIC-VLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPN 171
Query: 182 AFVSCGARVSSW 193
C +SW
Sbjct: 172 GDTYCTFNFASW 183
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 32.7 bits (73), Expect = 1.0
Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 28/114 (24%)
Query: 192 SWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAP--FGFSGVMAGTASCFYAFV 249
SWL H A+ LL + ++++ FAP G GV+ T++ F F+
Sbjct: 403 SWLRHVLIAVGLLTCINLLVI----------------FAPNILGIFGVIGATSAPFLIFI 446
Query: 250 -----GFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHS 298
F ++ E P RS P +A+ A+ G ++ ++ +++ W S
Sbjct: 447 FPAIFYFRIMPTEKE----PARSTPKILALCFAM-LGFLLMTMSLSFIIIDWAS 495
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 32.7 bits (73), Expect = 1.0
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 413 RFQKSSPPSSPGPASPGPLTKQQSSFSDHLQL-VGTVHA---------SVPEPGELKPAL 462
R Q P+SP PASPGP + S S+ Q+ +G A VP P + P
Sbjct: 632 RRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQP 691
Query: 463 RP 464
RP
Sbjct: 692 RP 693
>gi|239735603 POM121 membrane glycoprotein-like 12 [Homo sapiens]
Length = 296
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 12/57 (21%)
Query: 423 PGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPY-LGFLDGYSPGAVV 478
P P++ PL+K G V + VP PG LKP+L P+ L F D P +V
Sbjct: 212 PRPSAFKPLSKN-----------GAVASFVPRPGPLKPSLGPWSLSFCDDAWPSVLV 257
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 419 PPSSPGPASPGP-LTKQQSSFSDH--LQLVGTVHASVP 453
PP P P +PGP L +Q +S H +VG VHA P
Sbjct: 1627 PPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTP 1664
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,716,848
Number of Sequences: 37866
Number of extensions: 1062345
Number of successful extensions: 5195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 5080
Number of HSP's gapped (non-prelim): 101
length of query: 635
length of database: 18,247,518
effective HSP length: 109
effective length of query: 526
effective length of database: 14,120,124
effective search space: 7427185224
effective search space used: 7427185224
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.