BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] (211 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] 405 e-113 gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] 392 e-109 gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] 182 2e-46 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 46 3e-05 gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 45 3e-05 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 44 1e-04 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 1e-04 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 43 2e-04 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 43 2e-04 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 43 2e-04 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 3e-04 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 42 3e-04 gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 41 8e-04 gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 41 8e-04 gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 40 0.001 gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 40 0.001 gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 40 0.001 gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 40 0.001 gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 40 0.001 gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 40 0.001 gi|55770834 centromere protein F [Homo sapiens] 40 0.001 gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 40 0.002 gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 40 0.002 gi|42794779 myosin 18A isoform b [Homo sapiens] 40 0.002 gi|28416946 myosin 18A isoform a [Homo sapiens] 40 0.002 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.002 gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.002 gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 39 0.002 gi|4504063 golgin 97 [Homo sapiens] 39 0.003 gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 39 0.004 >gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] Length = 211 Score = 405 bits (1041), Expect = e-113 Identities = 211/211 (100%), Positives = 211/211 (100%) Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60 Query: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM Sbjct: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120 Query: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE Sbjct: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180 Query: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211 NKELRELLSISSESLQARKENSMDTASQAIK Sbjct: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211 >gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] Length = 207 Score = 392 bits (1007), Expect = e-109 Identities = 207/211 (98%), Positives = 207/211 (98%), Gaps = 4/211 (1%) Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ YQE Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ----YQE 56 Query: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM Sbjct: 57 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 116 Query: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE Sbjct: 117 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 176 Query: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211 NKELRELLSISSESLQARKENSMDTASQAIK Sbjct: 177 NKELRELLSISSESLQARKENSMDTASQAIK 207 >gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] Length = 253 Score = 182 bits (462), Expect = 2e-46 Identities = 106/250 (42%), Positives = 151/250 (60%), Gaps = 55/250 (22%) Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60 MSCTIEK L DAK L+ERLR+HD AAESL++Q+ AL++RV AM++ YQE Sbjct: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQ------------YQE 48 Query: 61 DASDMKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQM 116 + ++ ++++++P L QEN QIR+LQQEN+EL SLEEHQ ALELIMSKYR+QM Sbjct: 49 EIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM 108 Query: 117 LQLMVAKKAVDAEPVLKAHQSHSA------------------------------------ 140 +L++A K D ++K + HS Sbjct: 109 FRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEAN 168 Query: 141 --EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQA 197 E+++ +D+I EM VMRKA+++D+ Q CK QE++ QLE ENK LRE+L I+ ES L Sbjct: 169 QNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNL 228 Query: 198 RKENSMDTAS 207 RK+++ ++ S Sbjct: 229 RKDDASESTS 238 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 45.8 bits (107), Expect = 3e-05 Identities = 47/196 (23%), Positives = 93/196 (47%), Gaps = 22/196 (11%) Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65 +K+L + K ++L E A E+ +S +L + MR A + DQ+ +E+ + Sbjct: 1454 DKVLAEWK---QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510 Query: 66 KDMSKYKPHILLSQENTQIRD-----LQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120 +++S I + +N Q + ++QE +L ++LEE + +LE SK + L+L Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELS 1570 Query: 121 VAKKAVDAEPV--------LKAHQSHSAE-IESQID-RICEMGEVMRKAVQVDDDQFCKI 170 K +D + + LK + +AE ++S +D I + +R +++ D + Sbjct: 1571 QVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD----L 1626 Query: 171 QEKLAQLELENKELRE 186 E QL N+++ E Sbjct: 1627 NEMEIQLGHSNRQMAE 1642 Score = 35.4 bits (80), Expect = 0.036 Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 13/131 (9%) Query: 77 LSQENTQIRDLQQENRELWISLEEHQDAL-------ELIMSKYRKQMLQLMVAKKAVDAE 129 L QE DL++ R+L L+ Q+++ + I K +K+ +L + +D E Sbjct: 1042 LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDE 1101 Query: 130 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 189 V HS + + +I + E + + ++ + KI+++ + L E +E+ E L Sbjct: 1102 QV------HSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155 Query: 190 ISSESLQARKE 200 +S + A+ E Sbjct: 1156 EASGATSAQIE 1166 Score = 33.1 bits (74), Expect = 0.18 Identities = 48/229 (20%), Positives = 96/229 (41%), Gaps = 39/229 (17%) Query: 2 SCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQED 61 S EK + K ER +E A +E+ + L ++ ++ + L QV Q E+ Sbjct: 846 SAEAEKEMATMKEDFERTKEELARSEA---RRKELEEKMVSLLQEKNDLQLQV-QSETEN 901 Query: 62 ASDMKDMSK--YKPHILLSQENTQIRDLQQENREL--------------WISLEEHQDAL 105 D ++ + K ILL + ++ + +E E+ SL+ D L Sbjct: 902 LMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDL 961 Query: 106 ELIMSKYRKQM----------------LQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRI 149 EL ++K K+ L+ ++K + + + +AHQ +++ + D++ Sbjct: 962 ELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKV 1021 Query: 150 CEMGEVMRKAVQVDDDQFCKIQEK---LAQLELENKELRELLSISSESL 195 + ++ K Q DD ++++ A LE ++L L +S ES+ Sbjct: 1022 NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESI 1070 >gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] Length = 775 Score = 45.4 bits (106), Expect = 3e-05 Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 6/127 (4%) Query: 82 TQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLK----AHQS 137 ++++ ++ E + L+E Q+ + S ++ Q+ Q M +K AE L+ + Sbjct: 304 SELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEM--RKTALAEDQLRQQSQVEEQ 361 Query: 138 HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQA 197 A +E+QI + E+ KA Q D K++E++ QL+LENK L S S Sbjct: 362 RVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSH 421 Query: 198 RKENSMD 204 +E+S+D Sbjct: 422 GEESSLD 428 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/199 (20%), Positives = 95/199 (47%), Gaps = 6/199 (3%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 ++K +T+ K E++ + L ++ L + + + + L ++ Q D + Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAK 123 ++ + L + ++ LQ EN+EL E+ + LEL+ + ++K + L++ Sbjct: 704 LELRRNVES---LKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760 Query: 124 KAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKE 183 ++ + + K ++ + +I+ Q++ + E+ + +Q + ++ ++L QLE ENK Sbjct: 761 LDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819 Query: 184 L-RELLSISSESLQARKEN 201 L +E + + Q KEN Sbjct: 820 LEQETSQLEKDKKQLEKEN 838 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/186 (21%), Positives = 96/186 (51%), Gaps = 25/186 (13%) Query: 26 AESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIR 85 ++ L+ + A L + + +RE Q++ QE+ + +S + +S E +++ Sbjct: 528 SKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAE-ARVK 583 Query: 86 DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQ 145 D+++EN+ L S++E L I ++ K+ + KK ++ K + E+E++ Sbjct: 584 DIEKENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENE 633 Query: 146 IDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQ 196 + + + E+++K + ++ ++ ++++ ++LE EN++L++ L+ ESL+ Sbjct: 634 LHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 693 Query: 197 ARKENS 202 KENS Sbjct: 694 --KENS 697 Score = 31.6 bits (70), Expect = 0.51 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%) Query: 77 LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 130 + Q ++++DL+ EN+ L +LEE + + LE ++ QL KK ++ E Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838 Query: 131 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 188 Q+ + + + + ++G + + K + + + + +L +LE ENKEL + Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897 Query: 189 SISSESLQARKENSMDTASQAIK 211 +I ++L +E D S+ +K Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/199 (20%), Positives = 95/199 (47%), Gaps = 6/199 (3%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 ++K +T+ K E++ + L ++ L + + + + L ++ Q D + Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAK 123 ++ + L + ++ LQ EN+EL E+ + LEL+ + ++K + L++ Sbjct: 704 LELRRNVES---LKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760 Query: 124 KAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKE 183 ++ + + K ++ + +I+ Q++ + E+ + +Q + ++ ++L QLE ENK Sbjct: 761 LDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819 Query: 184 L-RELLSISSESLQARKEN 201 L +E + + Q KEN Sbjct: 820 LEQETSQLEKDKKQLEKEN 838 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/186 (21%), Positives = 96/186 (51%), Gaps = 25/186 (13%) Query: 26 AESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIR 85 ++ L+ + A L + + +RE Q++ QE+ + +S + +S E +++ Sbjct: 528 SKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAE-ARVK 583 Query: 86 DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQ 145 D+++EN+ L S++E L I ++ K+ + KK ++ K + E+E++ Sbjct: 584 DIEKENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENE 633 Query: 146 IDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQ 196 + + + E+++K + ++ ++ ++++ ++LE EN++L++ L+ ESL+ Sbjct: 634 LHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 693 Query: 197 ARKENS 202 KENS Sbjct: 694 --KENS 697 Score = 31.6 bits (70), Expect = 0.51 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%) Query: 77 LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 130 + Q ++++DL+ EN+ L +LEE + + LE ++ QL KK ++ E Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838 Query: 131 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 188 Q+ + + + + ++G + + K + + + + +L +LE ENKEL + Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897 Query: 189 SISSESLQARKENSMDTASQAIK 211 +I ++L +E D S+ +K Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 42.7 bits (99), Expect = 2e-04 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58 + K+ K L + E + E + Q+ +R+ + + A D+ R++ Sbjct: 1672 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1731 Query: 59 QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115 Q+D +M D +L ++ R L+ +L LEE Q EL+ +YRK Sbjct: 1732 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1787 Query: 116 MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173 +LQ+ + AE A +S ++E QI + +GE A ++ K Sbjct: 1788 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1847 Query: 174 LAQLE--LENKELRELLS 189 LAQ E LE + +LS Sbjct: 1848 LAQAEEQLEQETRERILS 1865 Score = 33.5 bits (75), Expect = 0.14 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%) Query: 83 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138 Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S Sbjct: 1671 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1725 Query: 139 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183 A ++Q DR EV + KA +++ + +++ +L QLE E +E Sbjct: 1726 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1772 Score = 31.6 bits (70), Expect = 0.51 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%) Query: 18 RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76 R+ E + + + + L + + + EA + RQ+ Q E + M K++ +L Sbjct: 955 RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1013 Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135 L ++ Q L +E + L L E K + L+L D E L+ Sbjct: 1014 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1071 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 + E+E R+ D + ++QE++ + + +ELR L E L Sbjct: 1072 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1117 Query: 196 Q---ARKENSMDTASQAIK 211 Q AR E+ +Q +K Sbjct: 1118 QAALARAEDEGGARAQLLK 1136 Score = 28.1 bits (61), Expect = 5.7 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%) Query: 11 DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64 +A L E+L E AA E + +++ R EAG ++ R+R +A Sbjct: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 + K + E + R LQQE + + LE+ + + + K RK QL+ +K Sbjct: 1429 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1486 Query: 125 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184 A V + ++ + E + + + +A++ + QE +LE +N+ L Sbjct: 1487 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1534 Query: 185 RELLSISSESLQARKEN 201 R L E+L + K++ Sbjct: 1535 RAEL----EALLSSKDD 1547 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 42.7 bits (99), Expect = 2e-04 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58 + K+ K L + E + E + Q+ +R+ + + A D+ R++ Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723 Query: 59 QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115 Q+D +M D +L ++ R L+ +L LEE Q EL+ +YRK Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 Query: 116 MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173 +LQ+ + AE A +S ++E QI + +GE A ++ K Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 Query: 174 LAQLE--LENKELRELLS 189 LAQ E LE + +LS Sbjct: 1840 LAQAEEQLEQETRERILS 1857 Score = 33.5 bits (75), Expect = 0.14 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%) Query: 83 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138 Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S Sbjct: 1663 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1717 Query: 139 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183 A ++Q DR EV + KA +++ + +++ +L QLE E +E Sbjct: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1764 Score = 31.6 bits (70), Expect = 0.51 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%) Query: 18 RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76 R+ E + + + + L + + + EA + RQ+ Q E + M K++ +L Sbjct: 947 RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1005 Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135 L ++ Q L +E + L L E K + L+L D E L+ Sbjct: 1006 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 + E+E R+ D + ++QE++ + + +ELR L E L Sbjct: 1064 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1109 Query: 196 Q---ARKENSMDTASQAIK 211 Q AR E+ +Q +K Sbjct: 1110 QAALARAEDEGGARAQLLK 1128 Score = 28.1 bits (61), Expect = 5.7 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%) Query: 11 DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64 +A L E+L E AA E + +++ R EAG ++ R+R +A Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 + K + E + R LQQE + + LE+ + + + K RK QL+ +K Sbjct: 1421 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1478 Query: 125 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184 A V + ++ + E + + + +A++ + QE +LE +N+ L Sbjct: 1479 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1526 Query: 185 RELLSISSESLQARKEN 201 R L E+L + K++ Sbjct: 1527 RAEL----EALLSSKDD 1539 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 42.7 bits (99), Expect = 2e-04 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58 + K+ K L + E + E + Q+ +R+ + + A D+ R++ Sbjct: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1764 Query: 59 QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115 Q+D +M D +L ++ R L+ +L LEE Q EL+ +YRK Sbjct: 1765 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1820 Query: 116 MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173 +LQ+ + AE A +S ++E QI + +GE A ++ K Sbjct: 1821 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1880 Query: 174 LAQLE--LENKELRELLS 189 LAQ E LE + +LS Sbjct: 1881 LAQAEEQLEQETRERILS 1898 Score = 33.5 bits (75), Expect = 0.14 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%) Query: 83 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138 Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S Sbjct: 1704 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1758 Query: 139 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183 A ++Q DR EV + KA +++ + +++ +L QLE E +E Sbjct: 1759 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1805 Score = 31.6 bits (70), Expect = 0.51 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%) Query: 18 RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76 R+ E + + + + L + + + EA + RQ+ Q E + M K++ +L Sbjct: 988 RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1046 Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135 L ++ Q L +E + L L E K + L+L D E L+ Sbjct: 1047 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1104 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 + E+E R+ D + ++QE++ + + +ELR L E L Sbjct: 1105 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1150 Query: 196 Q---ARKENSMDTASQAIK 211 Q AR E+ +Q +K Sbjct: 1151 QAALARAEDEGGARAQLLK 1169 Score = 28.1 bits (61), Expect = 5.7 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%) Query: 11 DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64 +A L E+L E AA E + +++ R EAG ++ R+R +A Sbjct: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 + K + E + R LQQE + + LE+ + + + K RK QL+ +K Sbjct: 1462 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1519 Query: 125 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184 A V + ++ + E + + + +A++ + QE +LE +N+ L Sbjct: 1520 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1567 Query: 185 RELLSISSESLQARKEN 201 R L E+L + K++ Sbjct: 1568 RAEL----EALLSSKDD 1580 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 42.4 bits (98), Expect = 3e-04 Identities = 42/198 (21%), Positives = 99/198 (50%), Gaps = 16/198 (8%) Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65 E++ +T + L++ E+L+ + + + +++ + ++ + + Q+ + + Sbjct: 828 EELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAI 887 Query: 66 KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDA---LELIMSKYRKQMLQLMVA 122 D+ K L Q Q+ + +E +EL SLE+ ++A L+L ++ ++Q++Q Sbjct: 888 LDLEKTCKE-LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQ---- 942 Query: 123 KKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK 182 A+ LK ++ +++ I+ + + E +K ++ + KI L + ELENK Sbjct: 943 -----AQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL-KI-AVLQKTELENK 995 Query: 183 ELRELLSISSESLQARKE 200 L++ L+ +++ L A KE Sbjct: 996 -LQQQLTQAAQELAAEKE 1012 Score = 38.9 bits (89), Expect = 0.003 Identities = 47/229 (20%), Positives = 98/229 (42%), Gaps = 26/229 (11%) Query: 6 EKILTDAKTLLERLRE-------HDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY 58 E+ + D + L RL E + + +D++ H+ A++++ TA + + Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511 Query: 59 QEDASDM--KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ- 115 ++ + KD LL + I L++E +L+ ++ + ++ K Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNH 571 Query: 116 MLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKA----------VQVDDD 165 LQ V + E + +SH E+ D++ E +R A V + Sbjct: 572 TLQEQVTQLT---EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNS 628 Query: 166 QFCKIQEKLAQLELENKELRELLSISSESLQARK---ENSMDTASQAIK 211 Q + +EK++QL+++ K ELL + + A++ +N +DTA A++ Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQ 677 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 42.4 bits (98), Expect = 3e-04 Identities = 39/165 (23%), Positives = 78/165 (47%), Gaps = 27/165 (16%) Query: 53 QVRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112 + R + +E+ S +KD + L ++ + Q QQ+ + ++EH+ +++ Sbjct: 698 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI---IKEHEVSIQRTEKAL 754 Query: 113 RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVD--------- 163 + Q+ QL + K D LK HQ+H +E+ I R GE+ + + ++D Sbjct: 755 KDQINQLELLLKERDKH--LKEHQAHVENLEADIKR--SEGELQQASAKLDVFQSYQSAT 810 Query: 164 -------DDQFCKIQEKLAQLELENKELRELLSISSESLQARKEN 201 ++Q ++Q+KL LE E R LL+ ++A+K++ Sbjct: 811 HEQTKAYEEQLAQLQQKLLDLETE----RILLTKQVAEVEAQKKD 851 Score = 37.4 bits (85), Expect = 0.009 Identities = 33/137 (24%), Positives = 70/137 (51%), Gaps = 8/137 (5%) Query: 55 RQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK 114 +++ Q+++ ++++ K IL EN ++RDLQQE + E + +LE + + + Sbjct: 527 QEKEQQESLALEELELQKKAILTESEN-KLRDLQQEAETYRTRILELESSLEKSLQENKN 585 Query: 115 QMLQLMV---AKKAVDAEPVLKAHQSHSAEIES---QIDRI-CEMGEVMRKAVQVDDDQF 167 Q L V A+K + + + H E+ES Q D + E +V+++ Q + ++ Sbjct: 586 QSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKL 645 Query: 168 CKIQEKLAQLELENKEL 184 + E+ + L++KE+ Sbjct: 646 REKCEQEKETLLKDKEI 662 Score = 36.2 bits (82), Expect = 0.021 Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 21/187 (11%) Query: 17 ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHI- 75 E+ H +S++ + +++ AL DQ+ Q K + +++ H+ Sbjct: 727 EQKNHHQQQVDSIIKEHEV------SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 780 Query: 76 -LLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKA 134 L + +LQQ + +L + + +Q A Y +Q+ QL ++ E +L Sbjct: 781 NLEADIKRSEGELQQASAKLDV-FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT 839 Query: 135 HQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES 194 Q AE+E+Q +C E+ +QV Q+ + QLE +N E+ + + ++ Sbjct: 840 KQV--AEVEAQKKDVCT--ELDAHKIQV--------QDLMQQLEKQNSEMEQKVKSLTQV 887 Query: 195 LQARKEN 201 +++ E+ Sbjct: 888 YESKLED 894 >gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] Length = 438 Score = 40.8 bits (94), Expect = 8e-04 Identities = 42/195 (21%), Positives = 94/195 (48%), Gaps = 15/195 (7%) Query: 16 LERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQR----YQEDASDMKDMSKY 71 +++LRE E ++ L +V + +EA + ++ ++ Y+E + + Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262 Query: 72 KPHILLSQENTQIRDLQQENRELW---ISLEEHQDA---LELIMSKYRKQMLQLMVAKKA 125 + LL + N+ ++ +++ N+++ ISLEE L+ ++ + K+ QL + + Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL--QL 320 Query: 126 VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185 ++ E + + S + Q ++ E +R+ ++ DD Q+K+ Q+ EN EL+ Sbjct: 321 LEHETEMSGELTDSDKERYQ--QLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378 Query: 186 ELLSISSESLQARKE 200 L +E+ QA+ E Sbjct: 379 SRLDYLTET-QAKTE 392 >gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] Length = 1044 Score = 40.8 bits (94), Expect = 8e-04 Identities = 48/213 (22%), Positives = 102/213 (47%), Gaps = 18/213 (8%) Query: 5 IEKILTDAKTLLER-------LREHDAAAESLVDQSAALHR-RVAAMREAGTALPDQVRQ 56 I++++ D K L E+ L++ D V Q+ A H + ++E +A R+ Sbjct: 631 IDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARRE 690 Query: 57 RY-QEDASDMKDMSK--YKPHI--LLSQENTQIRDLQQ-ENRELWISLEEHQDALELIMS 110 ++ E +K+++ +P I L+++ ++R L+ EL L+ + A + + Sbjct: 691 KWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAEL---LQSDERASQRCLR 747 Query: 111 KYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKI 170 + + QL K+A+ + +A Q AE+E ++ E + +A++ + ++ + Sbjct: 748 QAEELREQLEREKEALGQQERERARQRQRAELEELRQQLEESSSALTRALRAEFEKGREE 807 Query: 171 QEKLAQLELEN-KELRELLSISSESLQARKENS 202 QE+ Q+EL K+ EL + E+ + RKE + Sbjct: 808 QERRHQMELNTLKQQLELERQAWEAGRTRKEEA 840 >gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] Length = 983 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 591 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 650 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 651 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 702 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 703 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 762 Query: 197 ARK 199 +++ Sbjct: 763 SKE 765 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 651 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 703 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 704 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 763 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 764 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 821 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 822 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 852 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 852 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 911 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 912 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 961 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 962 DEDVQKVLK 970 >gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] Length = 972 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 580 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 639 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 640 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 691 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 692 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 751 Query: 197 ARK 199 +++ Sbjct: 752 SKE 754 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 640 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 692 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 693 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 752 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 753 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 810 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 811 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 841 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 841 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 900 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 901 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 950 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 951 DEDVQKVLK 959 >gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] Length = 951 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 559 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 618 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 619 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 670 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 671 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 730 Query: 197 ARK 199 +++ Sbjct: 731 SKE 733 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 619 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 671 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 672 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 731 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 732 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 789 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 790 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 820 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 820 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 879 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 880 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 929 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 930 DEDVQKVLK 938 >gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759 Query: 197 ARK 199 +++ Sbjct: 760 SKE 762 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 959 DEDVQKVLK 967 >gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759 Query: 197 ARK 199 +++ Sbjct: 760 SKE 762 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 959 DEDVQKVLK 967 >gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%) Query: 27 ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86 E++ + A L + +E L D ++ + ++ASD + K + ++ + N Q+ + Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647 Query: 87 LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139 L Q +E LE++ + +LE + ++Y ++++QL +A AE L Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699 Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196 +E++SQ ++ +++ V + I E L L KE+ E +S E L Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759 Query: 197 ARK 199 +++ Sbjct: 760 SKE 762 Score = 34.3 bits (77), Expect = 0.079 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63 + ++ +A+ LE R+ +SL D +A +H+ A E L + R + ++ S Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700 Query: 64 DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104 +MK ++++ K + +EN T +R +E E +L+EH + Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E+ ++K KQ+L+ A DA +++ + +ES++ + + K + Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818 Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195 + +I+ +++Q++ E + ++ LL + + Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849 Score = 28.1 bits (61), Expect = 5.7 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64 + ++L + E L E AES +++ M + T L + + Q S Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 +++ Q+ LQQ+ ++L L E + + ++S YR +L + + Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958 Query: 125 AVDAEPVLK 133 D + VLK Sbjct: 959 DEDVQKVLK 967 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 40.0 bits (92), Expect = 0.001 Identities = 46/205 (22%), Positives = 92/205 (44%), Gaps = 11/205 (5%) Query: 4 TIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDAS 63 T+ K T L E+++E ES QS LH + EA ++ Q D S Sbjct: 1969 TMSKKTTALDQLSEKMKEKTQELES--HQSECLH--CIQVAEAEVKEKTELLQTLSSDVS 2024 Query: 64 DM-KDMSKYKPHILLSQENTQIRDLQQENRELWIS-LEEHQDAL----ELIMSKYRKQML 117 ++ KD + + + ++++Q L + E I+ L + ++ L E + ++ + Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2084 Query: 118 QLMVAKKAVDAEPVLKAHQS-HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQ 176 + + KA++A V K + + + ++ ++ E +R ++ D+ + I EKL + Sbjct: 2085 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2144 Query: 177 LELENKELRELLSISSESLQARKEN 201 E EN L++ + LQ +EN Sbjct: 2145 RERENDSLKDKVENLERELQMSEEN 2169 Score = 35.0 bits (79), Expect = 0.047 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 15/127 (11%) Query: 77 LSQENTQIRDLQQENRELWISLEEHQ-DALELIMSKYRKQMLQLMVAKKAVDAEPVLKAH 135 +S++ T + L ++ +E LE HQ + L I Q+ + V +K +L+ Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCI------QVAEAEVKEKT----ELLQTL 2019 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 S +E+ + E + + K Q C+++ ++AQL NKE +ELL SESL Sbjct: 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL---NKE-KELLVKESESL 2075 Query: 196 QARKENS 202 QAR S Sbjct: 2076 QARLSES 2082 Score = 33.9 bits (76), Expect = 0.10 Identities = 51/217 (23%), Positives = 93/217 (42%), Gaps = 28/217 (12%) Query: 5 IEKILTDAKTLLERLR--------EHDAAAESLVDQSAALHRRVAAM---REAGTALPDQ 53 ++K+L+ K+LLE E A E L +Q L+ VAA+ +E A Sbjct: 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288 Query: 54 VRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR 113 + +E+ + K + L + E Q+ LQQ L+E + +L+ + Sbjct: 2289 LDPPIEEEHQLRNSIEKLRAR-LEADEKKQLCVLQQ--------LKESEHHADLLKGRVE 2339 Query: 114 KQMLQLMVAKK-----AVDAEPVLKAHQSHSAEIE--SQIDRICEMGEV-MRKAVQVDDD 165 +L +A+ A++AE ++ A+IE +Q R E+ V +R + + Sbjct: 2340 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399 Query: 166 QFCKIQEKLAQLELENKELRELLSISSESLQARKENS 202 + K QE++++LE+ N +L + KE S Sbjct: 2400 ELQKEQERISELEIINSSFENILQEKEQEKVQMKEKS 2436 Score = 32.0 bits (71), Expect = 0.39 Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 27/151 (17%) Query: 74 HILLSQENTQIR----DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 129 H L ++N ++R +L+Q+ + L QD LE++ S Y+ +L + K +D Sbjct: 2548 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTK--MDKM 2605 Query: 130 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD-----------------DQFCKIQE 172 ++ +A+ E+++ R EM E+ +K ++ + ++ ++ Sbjct: 2606 SFVEKVNKMTAK-ETELQR--EMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662 Query: 173 KLAQLELENKELRELLSISSESLQARKENSM 203 +L +L LEN EL++ L + Q KE + Sbjct: 2663 QLKELTLENSELKKSLDCMHKD-QVEKEGKV 2692 Score = 30.0 bits (66), Expect = 1.5 Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 20/182 (10%) Query: 21 EHDAAAESLVDQSAAL-----HRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHI 75 E+++ + L + A+L H+R + A+ E S + S+ + Sbjct: 759 EYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA 818 Query: 76 LLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAH 135 S +N+ I LQ L SLE + + S +KQ +L+ K ++ E ++KA Sbjct: 819 DQSPKNSAI--LQNRVDSLEFSLESQKQ----MNSDLQKQCEELVQIKGEIE-ENLMKAE 871 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 Q H + + RI ++ E V + E L+ LE + KEL +LL+ E+ Sbjct: 872 QMHQSFVAETSQRISKLQEDTSAHQNV-------VAETLSALENKEKEL-QLLNDKVETE 923 Query: 196 QA 197 QA Sbjct: 924 QA 925 >gi|219689136 coiled-coil domain containing 68 [Homo sapiens] Length = 335 Score = 39.7 bits (91), Expect = 0.002 Identities = 41/227 (18%), Positives = 97/227 (42%), Gaps = 35/227 (15%) Query: 15 LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY--------------QE 60 L+++++ D + ++ L ++ A REAG A V QR QE Sbjct: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE 150 Query: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR------- 113 D+ + ++K + L Q + + ++ E + E ++ ++ + + R Sbjct: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKL 210 Query: 114 ---KQMLQLMVA----KKAVDAEPVLKAHQSHSAEIE-------SQIDRICEMGEVMRKA 159 ++LQL + K D + + Q + ++ + + + E ++ Sbjct: 211 SLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNN 270 Query: 160 VQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTA 206 ++ D + ++EK+ LE +NKEL+ +++SSE+ + + ++ T+ Sbjct: 271 LKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTS 317 >gi|13376818 coiled-coil domain containing 68 [Homo sapiens] Length = 335 Score = 39.7 bits (91), Expect = 0.002 Identities = 41/227 (18%), Positives = 97/227 (42%), Gaps = 35/227 (15%) Query: 15 LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY--------------QE 60 L+++++ D + ++ L ++ A REAG A V QR QE Sbjct: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE 150 Query: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR------- 113 D+ + ++K + L Q + + ++ E + E ++ ++ + + R Sbjct: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKL 210 Query: 114 ---KQMLQLMVA----KKAVDAEPVLKAHQSHSAEIE-------SQIDRICEMGEVMRKA 159 ++LQL + K D + + Q + ++ + + + E ++ Sbjct: 211 SLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNN 270 Query: 160 VQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTA 206 ++ D + ++EK+ LE +NKEL+ +++SSE+ + + ++ T+ Sbjct: 271 LKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTS 317 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 39.7 bits (91), Expect = 0.002 Identities = 42/208 (20%), Positives = 92/208 (44%), Gaps = 21/208 (10%) Query: 8 ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQVRQRYQEDASD 64 +L DA+ +L+ L+ + + L AA +A A+ ++ + + Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ---- 1719 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 + D++K K + Q+ LQ+E E+ LEE Q+ + +M K++ + Q Sbjct: 1720 IDDIAKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA 1774 Query: 125 AV-DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELE 180 + D + L+ E++ ++ + E + +++ + Q KI+E +LE E Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE 1834 Query: 181 NKELRELLSISSESLQARKENSMDTASQ 208 +++ L ESL +R + +M+ ++ Sbjct: 1835 RTQVKRL-----ESLASRLKENMEKLTE 1857 Score = 33.5 bits (75), Expect = 0.14 Identities = 38/183 (20%), Positives = 80/183 (43%), Gaps = 26/183 (14%) Query: 20 REHD---AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHIL 76 RE D A A SL Q +A + +L +++ +++ D ++K K Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK--- 1542 Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDAEPVLKAH 135 Q+RDL+ + ++ L+E ++++ +K R +M + + Sbjct: 1543 ------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM-------------EMERMR 1583 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 Q+HS E+ES+ + + E + +K ++ + Q + E ++ E +EL L+ S+ + Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643 Query: 196 QAR 198 R Sbjct: 1644 NRR 1646 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 39.7 bits (91), Expect = 0.002 Identities = 42/208 (20%), Positives = 92/208 (44%), Gaps = 21/208 (10%) Query: 8 ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQVRQRYQEDASD 64 +L DA+ +L+ L+ + + L AA +A A+ ++ + + Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ---- 1719 Query: 65 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124 + D++K K + Q+ LQ+E E+ LEE Q+ + +M K++ + Q Sbjct: 1720 IDDIAKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA 1774 Query: 125 AV-DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELE 180 + D + L+ E++ ++ + E + +++ + Q KI+E +LE E Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE 1834 Query: 181 NKELRELLSISSESLQARKENSMDTASQ 208 +++ L ESL +R + +M+ ++ Sbjct: 1835 RTQVKRL-----ESLASRLKENMEKLTE 1857 Score = 33.5 bits (75), Expect = 0.14 Identities = 38/183 (20%), Positives = 80/183 (43%), Gaps = 26/183 (14%) Query: 20 REHD---AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHIL 76 RE D A A SL Q +A + +L +++ +++ D ++K K Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK--- 1542 Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDAEPVLKAH 135 Q+RDL+ + ++ L+E ++++ +K R +M + + Sbjct: 1543 ------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM-------------EMERMR 1583 Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195 Q+HS E+ES+ + + E + +K ++ + Q + E ++ E +EL L+ S+ + Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643 Query: 196 QAR 198 R Sbjct: 1644 NRR 1646 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 39.3 bits (90), Expect = 0.002 Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 34/197 (17%) Query: 2 SCTIEKILTDAKTLLERLR-----EHDAAAESLVDQSAALHR-RVAAMRE-AGTALPDQV 54 + ++++ + LERLR H+ L + HR + +++ G Q+ Sbjct: 608 NAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667 Query: 55 RQRYQEDASDMKDMSKYKPHILLSQ-----ENTQIRDLQQENRELWISLEEHQDALELIM 109 E + ++ M K +++ Q E ++++DLQQ L+ Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS----------------LVN 711 Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCK 169 SK + LQ+ +K ++ +L+ + +E ++ + E++ K ++ ++ Sbjct: 712 SKSEEMTLQINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEND--- 765 Query: 170 IQEKLAQLELENKELRE 186 +QEK AQLE EN L++ Sbjct: 766 LQEKFAQLEAENSILKD 782 Score = 36.2 bits (82), Expect = 0.021 Identities = 47/231 (20%), Positives = 100/231 (43%), Gaps = 46/231 (19%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE---- 60 I+++ + RL+E +A + + ++ L R+ AM+ + Q+ Q ++ Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004 Query: 61 ------DASDMKD-------------MSKYKPHILLSQE-NTQIRDLQQENRELWISLEE 100 A ++D + I L QE NT++ DL+Q+N+ L LE+ Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064 Query: 101 HQDAL--ELIMSKYRKQMLQLMVAK-----KAVDAEPVLKAHQSHSAE-----IESQIDR 148 + L + I ++ + + Q + K K V + HQ+ E ++ + D+ Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124 Query: 149 ICEM---GEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQ 196 E+ E +++ +Q + E++ +LE +EL + L +S+++ Q Sbjct: 2125 CSELLLSKEQLQRDIQ-------ERNEEIEKLEFRVRELEQALLVSADTFQ 2168 Score = 31.6 bits (70), Expect = 0.51 Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 14/196 (7%) Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65 EK +T+ + LE+ RE E+ ++ LH ++ ++ T ++ Q + DM Sbjct: 2202 EKEITNLEEQLEQFREE---LENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2258 Query: 66 KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKA 125 + + L +E+ + Q+ L+ + E+ + + +Q+ +L K Sbjct: 2259 EKLG------LAIKESDAMST--QDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKI 2310 Query: 126 VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185 V++ ++E+QI+ + E +++ + + +Q ++ EKL Q EL N + Sbjct: 2311 TTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELAN--IG 2367 Query: 186 ELLSISSESLQARKEN 201 + S+++ SL ++ Sbjct: 2368 QKTSMNAHSLSEEADS 2383 Score = 30.4 bits (67), Expect = 1.1 Identities = 34/184 (18%), Positives = 79/184 (42%), Gaps = 31/184 (16%) Query: 24 AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQ 83 A SL+ + ALH ++ + +R QE +++ +Y + Q+ +Q Sbjct: 3085 ADRRSLLSEIQALHAQMNGRKIT--------LKREQESEKPSQELLEYN----IQQKQSQ 3132 Query: 84 IRDLQQE---NRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSA 140 + ++Q E ++ L+E + ++++++ + ++ A+ ++ E LKA H Sbjct: 3133 MLEMQVELSSMKDRATELQEQLSSEKMVVAELKSEL-----AQTKLELETTLKAQHKHLK 3187 Query: 141 EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 200 E+E+ R V+ D+ + + LA + +++EL+ L L +E Sbjct: 3188 ELEA-----------FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEE 3236 Query: 201 NSMD 204 + Sbjct: 3237 RDKE 3240 Score = 28.9 bits (63), Expect = 3.3 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 30/150 (20%) Query: 54 VRQRYQEDAS-DMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112 VRQ ++ S D S+ ++L++E Q+ D++QE L +EHQ A EL+ + Sbjct: 1561 VRQSIHDEISVSSMDASR---QLMLNEE--QLEDMRQE---LVRQYQEHQQATELLRQAH 1612 Query: 113 RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE 172 +QM + + +++ +I R + + + +D++ +E Sbjct: 1613 MRQM----------------ERQREDQEQLQEEIKR---LNRQLAQRSSIDNENLVSERE 1653 Query: 173 KLAQLELENKELRELLSISSESLQARKENS 202 ++ ELE L++L E L NS Sbjct: 1654 RVLLEELE--ALKQLSLAGREKLCCELRNS 1681 >gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] Length = 3899 Score = 39.3 bits (90), Expect = 0.002 Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 34/197 (17%) Query: 2 SCTIEKILTDAKTLLERLR-----EHDAAAESLVDQSAALHR-RVAAMRE-AGTALPDQV 54 + ++++ + LERLR H+ L + HR + +++ G Q+ Sbjct: 608 NAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667 Query: 55 RQRYQEDASDMKDMSKYKPHILLSQ-----ENTQIRDLQQENRELWISLEEHQDALELIM 109 E + ++ M K +++ Q E ++++DLQQ L+ Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS----------------LVN 711 Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCK 169 SK + LQ+ +K ++ +L+ + +E ++ + E++ K ++ ++ Sbjct: 712 SKSEEMTLQINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEND--- 765 Query: 170 IQEKLAQLELENKELRE 186 +QEK AQLE EN L++ Sbjct: 766 LQEKFAQLEAENSILKD 782 Score = 35.0 bits (79), Expect = 0.047 Identities = 50/248 (20%), Positives = 106/248 (42%), Gaps = 50/248 (20%) Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE---- 60 I+++ + RL+E +A + + ++ L R+ AM+ + Q+ Q ++ Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004 Query: 61 ------DASDMKD-------------MSKYKPHILLSQE-NTQIRDLQQENRELWISLEE 100 A ++D + I L QE NT++ DL+Q+N+ L LE+ Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064 Query: 101 HQDAL--ELIMSKYRKQMLQLMVAK-----KAVDAEPVLKAHQSHSAE-----IESQIDR 148 + L + I ++ + + Q + K K V + HQ+ E ++ + D+ Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124 Query: 149 ICEM---GEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSE----SLQARKEN 201 E+ E +++ +Q + E++ +LE +EL + L + +++A+ E Sbjct: 2125 CSELLLSKEQLQRDIQ-------ERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPEL 2177 Query: 202 SMDTASQA 209 S++ QA Sbjct: 2178 SLEVQLQA 2185 Score = 31.6 bits (70), Expect = 0.51 Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 14/196 (7%) Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65 EK +T+ + LE+ RE E+ ++ LH ++ ++ T ++ Q + DM Sbjct: 2194 EKEITNLEEQLEQFREE---LENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250 Query: 66 KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKA 125 + + L +E+ + Q+ L+ + E+ + + +Q+ +L K Sbjct: 2251 EKLG------LAIKESDAMST--QDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKI 2302 Query: 126 VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185 V++ ++E+QI+ + E +++ + + +Q ++ EKL Q EL N + Sbjct: 2303 TTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELAN--IG 2359 Query: 186 ELLSISSESLQARKEN 201 + S+++ SL ++ Sbjct: 2360 QKTSMNAHSLSEEADS 2375 Score = 30.4 bits (67), Expect = 1.1 Identities = 34/184 (18%), Positives = 79/184 (42%), Gaps = 31/184 (16%) Query: 24 AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQ 83 A SL+ + ALH ++ + +R QE +++ +Y + Q+ +Q Sbjct: 3077 ADRRSLLSEIQALHAQMNGRKIT--------LKREQESEKPSQELLEYN----IQQKQSQ 3124 Query: 84 IRDLQQE---NRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSA 140 + ++Q E ++ L+E + ++++++ + ++ A+ ++ E LKA H Sbjct: 3125 MLEMQVELSSMKDRATELQEQLSSEKMVVAELKSEL-----AQTKLELETTLKAQHKHLK 3179 Query: 141 EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 200 E+E+ R V+ D+ + + LA + +++EL+ L L +E Sbjct: 3180 ELEA-----------FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEE 3228 Query: 201 NSMD 204 + Sbjct: 3229 RDKE 3232 Score = 28.9 bits (63), Expect = 3.3 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 30/150 (20%) Query: 54 VRQRYQEDAS-DMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112 VRQ ++ S D S+ ++L++E Q+ D++QE L +EHQ A EL+ + Sbjct: 1561 VRQSIHDEISVSSMDASR---QLMLNEE--QLEDMRQE---LVRQYQEHQQATELLRQAH 1612 Query: 113 RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE 172 +QM + + +++ +I R + + + +D++ +E Sbjct: 1613 MRQM----------------ERQREDQEQLQEEIKR---LNRQLAQRSSIDNENLVSERE 1653 Query: 173 KLAQLELENKELRELLSISSESLQARKENS 202 ++ ELE L++L E L NS Sbjct: 1654 RVLLEELE--ALKQLSLAGREKLCCELRNS 1681 >gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain 1 [Homo sapiens] Length = 1412 Score = 39.3 bits (90), Expect = 0.002 Identities = 54/229 (23%), Positives = 103/229 (44%), Gaps = 31/229 (13%) Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRV-AAMREAG---TALPDQVRQ 56 M ++KIL DAK L L + E L Q+ + R +AM ++G A ++ + Sbjct: 1188 MENNVQKILLDAKPDLPTL----SRIEILAPQNGLCNARFGSAMEKSGKMDVAEALELSE 1243 Query: 57 RYQEDAS-------DMKDMSKYKPHILLS-QENTQIRDLQQENRELWIS----LEEHQDA 104 + D S ++K+MS + LS QE ++ L+Q + +L L+ Sbjct: 1244 KLYLDMSKTLGSLMNIKNMSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQLKNQLGR 1303 Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164 E ++ Y K + QL +K +++ +QS A++E I + E ++++A++ + Sbjct: 1304 KEELLRGYEKDVEQLRRSKVSIEM------YQSQVAKLEDDIYKEAEEKALLKEALERME 1357 Query: 165 DQFCKIQEKLAQLELENKEL---RELLSISSESLQARKENSMDTASQAI 210 Q C QEK + +++ + L + E RKE S ++ + Sbjct: 1358 HQLC--QEKRINRAIRQQKVGTRKASLKMDQEREMLRKETSSKSSQSLL 1404 Score = 27.3 bits (59), Expect = 9.7 Identities = 33/170 (19%), Positives = 75/170 (44%), Gaps = 23/170 (13%) Query: 63 SDMKDMSKYKPHILLSQENTQIRDLQQENRELWIS-------------LEEHQDALELIM 109 SD + SKYK I+ + +N ++ +L Q+ E S L+E DA + + Sbjct: 241 SDYEIESKYKDVIIANLQN-EVAELSQKVSETTTSRQNEKEISQKCQVLDEDIDAKQKEI 299 Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICE-------MGEVMRKAVQV 162 + Q+ L V + L S ++++ + + M ++K + Sbjct: 300 QSLKSQISALQKGYSKVLCQ-TLSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILA 358 Query: 163 DDDQFCKIQEKLAQLELENKEL-RELLSISSESLQARKENSMDTASQAIK 211 D+Q +++E+++ L+ +NK+ +L ++ S ++E + A + ++ Sbjct: 359 KDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAHRELR 408 >gi|4504063 golgin 97 [Homo sapiens] Length = 767 Score = 38.9 bits (89), Expect = 0.003 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 7/136 (5%) Query: 77 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ 136 LS Q+R+LQ+ +L I+LE+HQD+ M K+++Q + A +A AE + A Sbjct: 74 LSDYAEQVRNLQKIKEKLEIALEKHQDS---SMRKFQEQN-ETFQANRAKMAEGLALALA 129 Query: 137 SHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQL-ELENKELRELLSISSESL 195 E ++D++ + ++ +Q +Q + ++ ++ ELE + +EL I + + Sbjct: 130 RKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKI--KHM 187 Query: 196 QARKENSMDTASQAIK 211 +KE S+ Q ++ Sbjct: 188 LLKKEESLGKMEQELE 203 >gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] Length = 1012 Score = 38.5 bits (88), Expect = 0.004 Identities = 34/153 (22%), Positives = 71/153 (46%), Gaps = 18/153 (11%) Query: 53 QVRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALEL----I 108 ++ + ++ED + K+ K + E ++E +I +E+ + L + Sbjct: 842 EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDV 901 Query: 109 MSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFC 168 +S +R+ Q +A+K ++A V++ Q E+E++ R+A + +D + Sbjct: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA----------RQAEEKFEDAY- 950 Query: 169 KIQEKLAQLELENKELRELLSISSESLQARKEN 201 EKL ++NK+L EL+ S + + KEN Sbjct: 951 ---EKLHHTLIKNKDLEELVMTSRKESKEEKEN 980 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.125 0.327 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,281,224 Number of Sequences: 37866 Number of extensions: 232781 Number of successful extensions: 1970 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 87 Number of HSP's successfully gapped in prelim test: 303 Number of HSP's that attempted gapping in prelim test: 1449 Number of HSP's gapped (non-prelim): 749 length of query: 211 length of database: 18,247,518 effective HSP length: 98 effective length of query: 113 effective length of database: 14,536,650 effective search space: 1642641450 effective search space used: 1642641450 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.