Guide to the Human Genome
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Search of human proteins with 156151379

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]       405   e-113
gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]       392   e-109
gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens]                   182   2e-46
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    46   3e-05
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 45   3e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    44   1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    44   1e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           43   2e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           43   2e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           43   2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             42   3e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     42   3e-04
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]         41   8e-04
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]          41   8e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         40   0.001
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         40   0.001
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         40   0.001
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         40   0.001
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         40   0.001
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         40   0.001
gi|55770834 centromere protein F [Homo sapiens]                        40   0.001
gi|219689136 coiled-coil domain containing 68 [Homo sapiens]           40   0.002
gi|13376818 coiled-coil domain containing 68 [Homo sapiens]            40   0.002
gi|42794779 myosin 18A isoform b [Homo sapiens]                        40   0.002
gi|28416946 myosin 18A isoform a [Homo sapiens]                        40   0.002
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         39   0.002
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         39   0.002
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    39   0.002
gi|4504063 golgin 97 [Homo sapiens]                                    39   0.003
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    39   0.004

>gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]
          Length = 211

 Score =  405 bits (1041), Expect = e-113
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60
           MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE
Sbjct: 1   MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60

Query: 61  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120
           DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
Sbjct: 61  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120

Query: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180
           VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
Sbjct: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180

Query: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211
           NKELRELLSISSESLQARKENSMDTASQAIK
Sbjct: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211


>gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]
          Length = 207

 Score =  392 bits (1007), Expect = e-109
 Identities = 207/211 (98%), Positives = 207/211 (98%), Gaps = 4/211 (1%)

Query: 1   MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60
           MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ    YQE
Sbjct: 1   MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ----YQE 56

Query: 61  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120
           DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
Sbjct: 57  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 116

Query: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180
           VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
Sbjct: 117 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 176

Query: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211
           NKELRELLSISSESLQARKENSMDTASQAIK
Sbjct: 177 NKELRELLSISSESLQARKENSMDTASQAIK 207


>gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens]
          Length = 253

 Score =  182 bits (462), Expect = 2e-46
 Identities = 106/250 (42%), Positives = 151/250 (60%), Gaps = 55/250 (22%)

Query: 1   MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60
           MSCTIEK L DAK L+ERLR+HD AAESL++Q+ AL++RV AM++            YQE
Sbjct: 1   MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQ------------YQE 48

Query: 61  DASDMKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQM 116
           +  ++ ++++++P   L     QEN QIR+LQQEN+EL  SLEEHQ ALELIMSKYR+QM
Sbjct: 49  EIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM 108

Query: 117 LQLMVAKKAVDAEPVLKAHQSHSA------------------------------------ 140
            +L++A K  D   ++K  + HS                                     
Sbjct: 109 FRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEAN 168

Query: 141 --EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQA 197
             E+++ +D+I EM  VMRKA+++D+ Q CK QE++ QLE ENK LRE+L I+ ES L  
Sbjct: 169 QNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNL 228

Query: 198 RKENSMDTAS 207
           RK+++ ++ S
Sbjct: 229 RKDDASESTS 238


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 47/196 (23%), Positives = 93/196 (47%), Gaps = 22/196 (11%)

Query: 6    EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65
            +K+L + K   ++L E  A  E+   +S +L   +  MR A   + DQ+    +E+ +  
Sbjct: 1454 DKVLAEWK---QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510

Query: 66   KDMSKYKPHILLSQENTQIRD-----LQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120
            +++S     I  + +N Q  +     ++QE  +L ++LEE + +LE   SK  +  L+L 
Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELS 1570

Query: 121  VAKKAVDAEPV--------LKAHQSHSAE-IESQID-RICEMGEVMRKAVQVDDDQFCKI 170
              K  +D + +        LK +   +AE ++S +D  I    + +R   +++ D    +
Sbjct: 1571 QVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD----L 1626

Query: 171  QEKLAQLELENKELRE 186
             E   QL   N+++ E
Sbjct: 1627 NEMEIQLGHSNRQMAE 1642



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 13/131 (9%)

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDAL-------ELIMSKYRKQMLQLMVAKKAVDAE 129
            L QE     DL++  R+L   L+  Q+++       + I  K +K+  +L   +  +D E
Sbjct: 1042 LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDE 1101

Query: 130  PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 189
             V      HS + + +I  +    E + + ++ +     KI+++ + L  E +E+ E L 
Sbjct: 1102 QV------HSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155

Query: 190  ISSESLQARKE 200
             +S +  A+ E
Sbjct: 1156 EASGATSAQIE 1166



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 48/229 (20%), Positives = 96/229 (41%), Gaps = 39/229 (17%)

Query: 2    SCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQED 61
            S   EK +   K   ER +E  A +E+   +   L  ++ ++ +    L  QV Q   E+
Sbjct: 846  SAEAEKEMATMKEDFERTKEELARSEA---RRKELEEKMVSLLQEKNDLQLQV-QSETEN 901

Query: 62   ASDMKDMSK--YKPHILLSQENTQIRDLQQENREL--------------WISLEEHQDAL 105
              D ++  +   K  ILL  +  ++ +  +E  E+                SL+   D L
Sbjct: 902  LMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDL 961

Query: 106  ELIMSKYRKQM----------------LQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRI 149
            EL ++K  K+                 L+  ++K   + + + +AHQ    +++ + D++
Sbjct: 962  ELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKV 1021

Query: 150  CEMGEVMRKAVQVDDDQFCKIQEK---LAQLELENKELRELLSISSESL 195
              + ++  K  Q  DD    ++++    A LE   ++L   L +S ES+
Sbjct: 1022 NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESI 1070


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 6/127 (4%)

Query: 82  TQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLK----AHQS 137
           ++++ ++ E  +    L+E Q+    + S ++ Q+ Q M  +K   AE  L+      + 
Sbjct: 304 SELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEM--RKTALAEDQLRQQSQVEEQ 361

Query: 138 HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQA 197
             A +E+QI  + E+     KA Q D     K++E++ QL+LENK L    S  S     
Sbjct: 362 RVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSH 421

Query: 198 RKENSMD 204
            +E+S+D
Sbjct: 422 GEESSLD 428


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 40/199 (20%), Positives = 95/199 (47%), Gaps = 6/199 (3%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           ++K +T+ K   E++   +     L  ++  L + + + +     L    ++  Q D  +
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAK 123
           ++     +    L   + ++  LQ EN+EL    E+ +  LEL+ + ++K + L++    
Sbjct: 704 LELRRNVES---LKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760

Query: 124 KAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKE 183
             ++ + + K  ++ + +I+ Q++   +  E+  + +Q + ++     ++L QLE ENK 
Sbjct: 761 LDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819

Query: 184 L-RELLSISSESLQARKEN 201
           L +E   +  +  Q  KEN
Sbjct: 820 LEQETSQLEKDKKQLEKEN 838



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/186 (21%), Positives = 96/186 (51%), Gaps = 25/186 (13%)

Query: 26  AESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIR 85
           ++ L+ + A L + +  +RE       Q++   QE+    + +S  +    +S E  +++
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAE-ARVK 583

Query: 86  DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQ 145
           D+++EN+ L  S++E    L  I  ++ K+ +     KK ++     K     + E+E++
Sbjct: 584 DIEKENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENE 633

Query: 146 IDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQ 196
           +  + +  E+++K +   ++  ++   ++++ ++LE EN++L++       L+   ESL+
Sbjct: 634 LHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 693

Query: 197 ARKENS 202
             KENS
Sbjct: 694 --KENS 697



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%)

Query: 77  LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 130
           + Q  ++++DL+ EN+ L  +LEE +      + LE       ++  QL   KK ++ E 
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838

Query: 131 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 188
                Q+   +   + + + ++G + +  K +  +   + +   +L +LE ENKEL +  
Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897

Query: 189 SISSESLQARKENSMDTASQAIK 211
           +I  ++L   +E   D  S+ +K
Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 40/199 (20%), Positives = 95/199 (47%), Gaps = 6/199 (3%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           ++K +T+ K   E++   +     L  ++  L + + + +     L    ++  Q D  +
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAK 123
           ++     +    L   + ++  LQ EN+EL    E+ +  LEL+ + ++K + L++    
Sbjct: 704 LELRRNVES---LKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760

Query: 124 KAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKE 183
             ++ + + K  ++ + +I+ Q++   +  E+  + +Q + ++     ++L QLE ENK 
Sbjct: 761 LDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKS 819

Query: 184 L-RELLSISSESLQARKEN 201
           L +E   +  +  Q  KEN
Sbjct: 820 LEQETSQLEKDKKQLEKEN 838



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/186 (21%), Positives = 96/186 (51%), Gaps = 25/186 (13%)

Query: 26  AESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIR 85
           ++ L+ + A L + +  +RE       Q++   QE+    + +S  +    +S E  +++
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQISAE-ARVK 583

Query: 86  DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQ 145
           D+++EN+ L  S++E    L  I  ++ K+ +     KK ++     K     + E+E++
Sbjct: 584 DIEKENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENE 633

Query: 146 IDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQ 196
           +  + +  E+++K +   ++  ++   ++++ ++LE EN++L++       L+   ESL+
Sbjct: 634 LHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 693

Query: 197 ARKENS 202
             KENS
Sbjct: 694 --KENS 697



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%)

Query: 77  LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 130
           + Q  ++++DL+ EN+ L  +LEE +      + LE       ++  QL   KK ++ E 
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838

Query: 131 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 188
                Q+   +   + + + ++G + +  K +  +   + +   +L +LE ENKEL +  
Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897

Query: 189 SISSESLQARKENSMDTASQAIK 211
           +I  ++L   +E   D  S+ +K
Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%)

Query: 5    IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58
            + K+    K L   + E   + E +  Q+    +R+  +       +   A  D+ R++ 
Sbjct: 1672 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1731

Query: 59   QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115
            Q+D  +M D           +L ++    R L+    +L   LEE Q   EL+  +YRK 
Sbjct: 1732 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1787

Query: 116  MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173
            +LQ+      + AE    A  +S   ++E QI  +   +GE    A          ++ K
Sbjct: 1788 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1847

Query: 174  LAQLE--LENKELRELLS 189
            LAQ E  LE +    +LS
Sbjct: 1848 LAQAEEQLEQETRERILS 1865



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)

Query: 83   QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138
            Q+R +Q + +ELW  +EE + + E I S+ R+   +L    K ++AE VL+  +    S 
Sbjct: 1671 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1725

Query: 139  SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183
             A  ++Q DR     EV    + KA  +++ +  +++ +L QLE E +E
Sbjct: 1726 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1772



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%)

Query: 18   RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76
            R+ E +  +  +  +   L + +  + EA     +  RQ+ Q E  +    M K++  +L
Sbjct: 955  RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1013

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135
            L ++  Q   L +E + L   L E          K +    L+L       D E  L+  
Sbjct: 1014 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1071

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
            +    E+E    R+              D +  ++QE++ + +   +ELR  L    E L
Sbjct: 1072 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1117

Query: 196  Q---ARKENSMDTASQAIK 211
            Q   AR E+     +Q +K
Sbjct: 1118 QAALARAEDEGGARAQLLK 1136



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%)

Query: 11   DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64
            +A  L E+L E  AA E    +      +++  R     EAG     ++ R+R   +A  
Sbjct: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428

Query: 65   MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
            +      K   +   E  + R LQQE  +  + LE+ +  +  +  K RK   QL+  +K
Sbjct: 1429 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1486

Query: 125  AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184
            A     V +  ++ +   E +   +      + +A++ +       QE   +LE +N+ L
Sbjct: 1487 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1534

Query: 185  RELLSISSESLQARKEN 201
            R  L    E+L + K++
Sbjct: 1535 RAEL----EALLSSKDD 1547


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%)

Query: 5    IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58
            + K+    K L   + E   + E +  Q+    +R+  +       +   A  D+ R++ 
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723

Query: 59   QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115
            Q+D  +M D           +L ++    R L+    +L   LEE Q   EL+  +YRK 
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779

Query: 116  MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173
            +LQ+      + AE    A  +S   ++E QI  +   +GE    A          ++ K
Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839

Query: 174  LAQLE--LENKELRELLS 189
            LAQ E  LE +    +LS
Sbjct: 1840 LAQAEEQLEQETRERILS 1857



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)

Query: 83   QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138
            Q+R +Q + +ELW  +EE + + E I S+ R+   +L    K ++AE VL+  +    S 
Sbjct: 1663 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1717

Query: 139  SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183
             A  ++Q DR     EV    + KA  +++ +  +++ +L QLE E +E
Sbjct: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1764



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%)

Query: 18   RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76
            R+ E +  +  +  +   L + +  + EA     +  RQ+ Q E  +    M K++  +L
Sbjct: 947  RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1005

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135
            L ++  Q   L +E + L   L E          K +    L+L       D E  L+  
Sbjct: 1006 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
            +    E+E    R+              D +  ++QE++ + +   +ELR  L    E L
Sbjct: 1064 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1109

Query: 196  Q---ARKENSMDTASQAIK 211
            Q   AR E+     +Q +K
Sbjct: 1110 QAALARAEDEGGARAQLLK 1128



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%)

Query: 11   DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64
            +A  L E+L E  AA E    +      +++  R     EAG     ++ R+R   +A  
Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420

Query: 65   MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
            +      K   +   E  + R LQQE  +  + LE+ +  +  +  K RK   QL+  +K
Sbjct: 1421 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1478

Query: 125  AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184
            A     V +  ++ +   E +   +      + +A++ +       QE   +LE +N+ L
Sbjct: 1479 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1526

Query: 185  RELLSISSESLQARKEN 201
            R  L    E+L + K++
Sbjct: 1527 RAEL----EALLSSKDD 1539


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 17/198 (8%)

Query: 5    IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMR------EAGTALPDQVRQRY 58
            + K+    K L   + E   + E +  Q+    +R+  +       +   A  D+ R++ 
Sbjct: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1764

Query: 59   QEDASDMKDM---SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ 115
            Q+D  +M D           +L ++    R L+    +L   LEE Q   EL+  +YRK 
Sbjct: 1765 QQDRDEMADEVANGNLSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1820

Query: 116  MLQLMVAKKAVDAEPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEK 173
            +LQ+      + AE    A  +S   ++E QI  +   +GE    A          ++ K
Sbjct: 1821 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1880

Query: 174  LAQLE--LENKELRELLS 189
            LAQ E  LE +    +LS
Sbjct: 1881 LAQAEEQLEQETRERILS 1898



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)

Query: 83   QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 138
            Q+R +Q + +ELW  +EE + + E I S+ R+   +L    K ++AE VL+  +    S 
Sbjct: 1704 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1758

Query: 139  SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 183
             A  ++Q DR     EV    + KA  +++ +  +++ +L QLE E +E
Sbjct: 1759 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1805



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 43/199 (21%), Positives = 78/199 (39%), Gaps = 22/199 (11%)

Query: 18   RLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQ-EDASDMKDMSKYKPHIL 76
            R+ E +  +  +  +   L + +  + EA     +  RQ+ Q E  +    M K++  +L
Sbjct: 988  RVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 1046

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAVDAEPVLKAH 135
            L ++  Q   L +E + L   L E          K +    L+L       D E  L+  
Sbjct: 1047 LLED--QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1104

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
            +    E+E    R+              D +  ++QE++ + +   +ELR  L    E L
Sbjct: 1105 EKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1150

Query: 196  Q---ARKENSMDTASQAIK 211
            Q   AR E+     +Q +K
Sbjct: 1151 QAALARAEDEGGARAQLLK 1169



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 24/197 (12%)

Query: 11   DAKTLLERLREHDAAAESLVDQSAALHRRVAAMR-----EAGTA-LPDQVRQRYQEDASD 64
            +A  L E+L E  AA E    +      +++  R     EAG     ++ R+R   +A  
Sbjct: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461

Query: 65   MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
            +      K   +   E  + R LQQE  +  + LE+ +  +  +  K RK   QL+  +K
Sbjct: 1462 LTQRLAEKTETVDRLERGR-RRLQQELDDATMDLEQQRQLVSTLEKKQRK-FDQLLAEEK 1519

Query: 125  AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 184
            A     V +  ++ +   E +   +      + +A++ +       QE   +LE +N+ L
Sbjct: 1520 AAVLRAVEERERAEAEGREREARALS-----LTRALEEE-------QEAREELERQNRAL 1567

Query: 185  RELLSISSESLQARKEN 201
            R  L    E+L + K++
Sbjct: 1568 RAEL----EALLSSKDD 1580


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 42/198 (21%), Positives = 99/198 (50%), Gaps = 16/198 (8%)

Query: 6    EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65
            E++    +T +  L++     E+L+ + + +  +++ + ++      +  +  Q+  + +
Sbjct: 828  EELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAI 887

Query: 66   KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDA---LELIMSKYRKQMLQLMVA 122
             D+ K     L  Q   Q+ +  +E +EL  SLE+ ++A   L+L ++  ++Q++Q    
Sbjct: 888  LDLEKTCKE-LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQ---- 942

Query: 123  KKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK 182
                 A+  LK ++    +++  I+ + +  E  +K ++    +  KI   L + ELENK
Sbjct: 943  -----AQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL-KI-AVLQKTELENK 995

Query: 183  ELRELLSISSESLQARKE 200
             L++ L+ +++ L A KE
Sbjct: 996  -LQQQLTQAAQELAAEKE 1012



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 47/229 (20%), Positives = 98/229 (42%), Gaps = 26/229 (11%)

Query: 6   EKILTDAKTLLERLRE-------HDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY 58
           E+ + D +  L RL E       +    +  +D++   H+   A++++ TA   + +   
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511

Query: 59  QEDASDM--KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ- 115
           ++    +  KD        LL +    I  L++E  +L+  ++  +    ++     K  
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNH 571

Query: 116 MLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKA----------VQVDDD 165
            LQ  V +     E +    +SH    E+  D++ E    +R A          V   + 
Sbjct: 572 TLQEQVTQLT---EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNS 628

Query: 166 QFCKIQEKLAQLELENKELRELLSISSESLQARK---ENSMDTASQAIK 211
           Q  + +EK++QL+++ K   ELL  +  +  A++   +N +DTA  A++
Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQ 677


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 39/165 (23%), Positives = 78/165 (47%), Gaps = 27/165 (16%)

Query: 53  QVRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112
           + R + +E+ S +KD +      L ++ + Q    QQ+   +   ++EH+ +++      
Sbjct: 698 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI---IKEHEVSIQRTEKAL 754

Query: 113 RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVD--------- 163
           + Q+ QL +  K  D    LK HQ+H   +E+ I R    GE+ + + ++D         
Sbjct: 755 KDQINQLELLLKERDKH--LKEHQAHVENLEADIKR--SEGELQQASAKLDVFQSYQSAT 810

Query: 164 -------DDQFCKIQEKLAQLELENKELRELLSISSESLQARKEN 201
                  ++Q  ++Q+KL  LE E    R LL+     ++A+K++
Sbjct: 811 HEQTKAYEEQLAQLQQKLLDLETE----RILLTKQVAEVEAQKKD 851



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 33/137 (24%), Positives = 70/137 (51%), Gaps = 8/137 (5%)

Query: 55  RQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK 114
           +++ Q+++  ++++   K  IL   EN ++RDLQQE       + E + +LE  + + + 
Sbjct: 527 QEKEQQESLALEELELQKKAILTESEN-KLRDLQQEAETYRTRILELESSLEKSLQENKN 585

Query: 115 QMLQLMV---AKKAVDAEPVLKAHQSHSAEIES---QIDRI-CEMGEVMRKAVQVDDDQF 167
           Q   L V   A+K    + +    + H  E+ES   Q D +  E  +V+++  Q + ++ 
Sbjct: 586 QSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKL 645

Query: 168 CKIQEKLAQLELENKEL 184
            +  E+  +  L++KE+
Sbjct: 646 REKCEQEKETLLKDKEI 662



 Score = 36.2 bits (82), Expect = 0.021
 Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 21/187 (11%)

Query: 17  ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHI- 75
           E+   H    +S++ +         +++    AL DQ+ Q         K + +++ H+ 
Sbjct: 727 EQKNHHQQQVDSIIKEHEV------SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 780

Query: 76  -LLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKA 134
            L +       +LQQ + +L +  + +Q A       Y +Q+ QL      ++ E +L  
Sbjct: 781 NLEADIKRSEGELQQASAKLDV-FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT 839

Query: 135 HQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES 194
            Q   AE+E+Q   +C   E+    +QV        Q+ + QLE +N E+ + +   ++ 
Sbjct: 840 KQV--AEVEAQKKDVCT--ELDAHKIQV--------QDLMQQLEKQNSEMEQKVKSLTQV 887

Query: 195 LQARKEN 201
            +++ E+
Sbjct: 888 YESKLED 894


>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
          Length = 438

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 42/195 (21%), Positives = 94/195 (48%), Gaps = 15/195 (7%)

Query: 16  LERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQR----YQEDASDMKDMSKY 71
           +++LRE     E    ++  L  +V + +EA   +  ++ ++    Y+E   + +     
Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262

Query: 72  KPHILLSQENTQIRDLQQENRELW---ISLEEHQDA---LELIMSKYRKQMLQLMVAKKA 125
           +   LL + N+ ++ +++ N+++    ISLEE       L+ ++ +  K+  QL +  + 
Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL--QL 320

Query: 126 VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185
           ++ E  +    + S +   Q  ++ E    +R+ ++  DD     Q+K+ Q+  EN EL+
Sbjct: 321 LEHETEMSGELTDSDKERYQ--QLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378

Query: 186 ELLSISSESLQARKE 200
             L   +E+ QA+ E
Sbjct: 379 SRLDYLTET-QAKTE 392


>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
          Length = 1044

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 48/213 (22%), Positives = 102/213 (47%), Gaps = 18/213 (8%)

Query: 5   IEKILTDAKTLLER-------LREHDAAAESLVDQSAALHR-RVAAMREAGTALPDQVRQ 56
           I++++ D K L E+       L++ D      V Q+ A H   +  ++E  +A     R+
Sbjct: 631 IDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARRE 690

Query: 57  RY-QEDASDMKDMSK--YKPHI--LLSQENTQIRDLQQ-ENRELWISLEEHQDALELIMS 110
           ++  E    +K+++    +P I  L+++   ++R L+     EL   L+  + A +  + 
Sbjct: 691 KWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAEL---LQSDERASQRCLR 747

Query: 111 KYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKI 170
           +  +   QL   K+A+  +   +A Q   AE+E    ++ E    + +A++ + ++  + 
Sbjct: 748 QAEELREQLEREKEALGQQERERARQRQRAELEELRQQLEESSSALTRALRAEFEKGREE 807

Query: 171 QEKLAQLELEN-KELRELLSISSESLQARKENS 202
           QE+  Q+EL   K+  EL   + E+ + RKE +
Sbjct: 808 QERRHQMELNTLKQQLELERQAWEAGRTRKEEA 840


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 591 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 650

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 651 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 702

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 703 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 762

Query: 197 ARK 199
           +++
Sbjct: 763 SKE 765



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 651 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 703

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 704 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 763

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 764 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 821

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 822 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 852



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 852 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 911

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 912 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 961

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 962 DEDVQKVLK 970


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 580 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 639

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 640 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 691

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 692 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 751

Query: 197 ARK 199
           +++
Sbjct: 752 SKE 754



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 640 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 692

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 693 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 752

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 753 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 810

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 811 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 841



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 841 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 900

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 901 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 950

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 951 DEDVQKVLK 959


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 559 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 618

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 619 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 670

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 671 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 730

Query: 197 ARK 199
           +++
Sbjct: 731 SKE 733



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 619 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 671

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 672 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 731

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 732 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 789

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 790 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 820



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 820 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 879

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 880 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 929

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 930 DEDVQKVLK 938


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759

Query: 197 ARK 199
           +++
Sbjct: 760 SKE 762



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 959 DEDVQKVLK 967


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759

Query: 197 ARK 199
           +++
Sbjct: 760 SKE 762



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 959 DEDVQKVLK 967


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 18/183 (9%)

Query: 27  ESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRD 86
           E++  + A L  +    +E    L D ++ +  ++ASD  +  K   + ++ + N Q+ +
Sbjct: 588 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSE 647

Query: 87  LQQENRELWISLEEH--QDALELIMSKY-----RKQMLQLMVAKKAVDAEPVLKAHQSHS 139
           L Q  +E    LE++  + +LE + ++Y      ++++QL    +A  AE  L       
Sbjct: 648 LSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRA-KAEDAL------- 699

Query: 140 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKL---AQLELENKELRELLSISSESLQ 196
           +E++SQ  ++      +++ V    +    I E L     L    KE+ E +S   E L 
Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 759

Query: 197 ARK 199
           +++
Sbjct: 760 SKE 762



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 29/211 (13%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDAS 63
           + ++  +A+  LE  R+     +SL D +A  +H+   A  E    L +  R + ++  S
Sbjct: 648 LSQLYKEAQAELEDYRKR----KSLEDVTAEYIHK---AEHEKLMQLTNVSRAKAEDALS 700

Query: 64  DMK--------DMSKYKPHILLSQEN-----------TQIRDLQQENRELWISLEEHQDA 104
           +MK        ++++ K  +   +EN           T +R   +E  E   +L+EH  +
Sbjct: 701 EMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAS 760

Query: 105 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
            E+ ++K  KQ+L+   A    DA     +++   + +ES++  +    +   K  +   
Sbjct: 761 KEVEVAKLEKQLLEEKAA--MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818

Query: 165 DQFCKIQEKLAQLELENKELRELLSISSESL 195
            +  +I+ +++Q++ E + ++ LL    + +
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEV 849



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 5   IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASD 64
           + ++L   +   E L E    AES         +++  M +  T L + +    Q   S 
Sbjct: 849 VNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 908

Query: 65  MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
                         +++ Q+  LQQ+ ++L   L E +   + ++S YR  +L  +  + 
Sbjct: 909 SSS----------KRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM 958

Query: 125 AVDAEPVLK 133
             D + VLK
Sbjct: 959 DEDVQKVLK 967


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 46/205 (22%), Positives = 92/205 (44%), Gaps = 11/205 (5%)

Query: 4    TIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDAS 63
            T+ K  T    L E+++E     ES   QS  LH     + EA      ++ Q    D S
Sbjct: 1969 TMSKKTTALDQLSEKMKEKTQELES--HQSECLH--CIQVAEAEVKEKTELLQTLSSDVS 2024

Query: 64   DM-KDMSKYKPHILLSQENTQIRDLQQENRELWIS-LEEHQDAL----ELIMSKYRKQML 117
            ++ KD +  +  +   ++++Q   L +   E  I+ L + ++ L    E + ++  +   
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2084

Query: 118  QLMVAKKAVDAEPVLKAHQS-HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQ 176
            + +   KA++A  V K   +   +  + ++ ++    E +R  ++ D+ +   I EKL +
Sbjct: 2085 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2144

Query: 177  LELENKELRELLSISSESLQARKEN 201
             E EN  L++ +      LQ  +EN
Sbjct: 2145 RERENDSLKDKVENLERELQMSEEN 2169



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 15/127 (11%)

Query: 77   LSQENTQIRDLQQENRELWISLEEHQ-DALELIMSKYRKQMLQLMVAKKAVDAEPVLKAH 135
            +S++ T +  L ++ +E    LE HQ + L  I      Q+ +  V +K      +L+  
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCI------QVAEAEVKEKT----ELLQTL 2019

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
             S  +E+      + E  + + K  Q      C+++ ++AQL   NKE +ELL   SESL
Sbjct: 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL---NKE-KELLVKESESL 2075

Query: 196  QARKENS 202
            QAR   S
Sbjct: 2076 QARLSES 2082



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 51/217 (23%), Positives = 93/217 (42%), Gaps = 28/217 (12%)

Query: 5    IEKILTDAKTLLERLR--------EHDAAAESLVDQSAALHRRVAAM---REAGTALPDQ 53
            ++K+L+  K+LLE           E   A E L +Q   L+  VAA+   +E   A    
Sbjct: 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288

Query: 54   VRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR 113
            +    +E+      + K +   L + E  Q+  LQQ        L+E +   +L+  +  
Sbjct: 2289 LDPPIEEEHQLRNSIEKLRAR-LEADEKKQLCVLQQ--------LKESEHHADLLKGRVE 2339

Query: 114  KQMLQLMVAKK-----AVDAEPVLKAHQSHSAEIE--SQIDRICEMGEV-MRKAVQVDDD 165
                +L +A+      A++AE      ++  A+IE  +Q  R  E+  V +R   +   +
Sbjct: 2340 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399

Query: 166  QFCKIQEKLAQLELENKELRELLSISSESLQARKENS 202
            +  K QE++++LE+ N     +L    +     KE S
Sbjct: 2400 ELQKEQERISELEIINSSFENILQEKEQEKVQMKEKS 2436



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 27/151 (17%)

Query: 74   HILLSQENTQIR----DLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 129
            H L  ++N ++R    +L+Q+ + L       QD LE++ S Y+    +L + K  +D  
Sbjct: 2548 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTK--MDKM 2605

Query: 130  PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD-----------------DQFCKIQE 172
              ++     +A+ E+++ R  EM E+ +K  ++ +                 ++    ++
Sbjct: 2606 SFVEKVNKMTAK-ETELQR--EMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662

Query: 173  KLAQLELENKELRELLSISSESLQARKENSM 203
            +L +L LEN EL++ L    +  Q  KE  +
Sbjct: 2663 QLKELTLENSELKKSLDCMHKD-QVEKEGKV 2692



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 20/182 (10%)

Query: 21  EHDAAAESLVDQSAAL-----HRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHI 75
           E+++  + L  + A+L     H+R     +   A+         E  S   + S+ +   
Sbjct: 759 EYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA 818

Query: 76  LLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAH 135
             S +N+ I  LQ     L  SLE  +     + S  +KQ  +L+  K  ++ E ++KA 
Sbjct: 819 DQSPKNSAI--LQNRVDSLEFSLESQKQ----MNSDLQKQCEELVQIKGEIE-ENLMKAE 871

Query: 136 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
           Q H + +     RI ++ E       V       + E L+ LE + KEL +LL+   E+ 
Sbjct: 872 QMHQSFVAETSQRISKLQEDTSAHQNV-------VAETLSALENKEKEL-QLLNDKVETE 923

Query: 196 QA 197
           QA
Sbjct: 924 QA 925


>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
          Length = 335

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 41/227 (18%), Positives = 97/227 (42%), Gaps = 35/227 (15%)

Query: 15  LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY--------------QE 60
           L+++++  D     +  ++  L  ++ A REAG A    V QR               QE
Sbjct: 91  LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE 150

Query: 61  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR------- 113
           D+  +  ++K +    L Q    +  + ++  E    + E ++ ++ +  + R       
Sbjct: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKL 210

Query: 114 ---KQMLQLMVA----KKAVDAEPVLKAHQSHSAEIE-------SQIDRICEMGEVMRKA 159
               ++LQL  +    K   D +  +   Q   + ++         +  + +  E ++  
Sbjct: 211 SLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNN 270

Query: 160 VQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTA 206
           ++  D +   ++EK+  LE +NKEL+  +++SSE+ + +   ++ T+
Sbjct: 271 LKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTS 317


>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
          Length = 335

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 41/227 (18%), Positives = 97/227 (42%), Gaps = 35/227 (15%)

Query: 15  LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRY--------------QE 60
           L+++++  D     +  ++  L  ++ A REAG A    V QR               QE
Sbjct: 91  LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE 150

Query: 61  DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR------- 113
           D+  +  ++K +    L Q    +  + ++  E    + E ++ ++ +  + R       
Sbjct: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKL 210

Query: 114 ---KQMLQLMVA----KKAVDAEPVLKAHQSHSAEIE-------SQIDRICEMGEVMRKA 159
               ++LQL  +    K   D +  +   Q   + ++         +  + +  E ++  
Sbjct: 211 SLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNN 270

Query: 160 VQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTA 206
           ++  D +   ++EK+  LE +NKEL+  +++SSE+ + +   ++ T+
Sbjct: 271 LKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTS 317


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 42/208 (20%), Positives = 92/208 (44%), Gaps = 21/208 (10%)

Query: 8    ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQVRQRYQEDASD 64
            +L DA+ +L+ L+    +   +      L       AA  +A  A+  ++   + +    
Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ---- 1719

Query: 65   MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
            + D++K K  +       Q+  LQ+E  E+   LEE Q+ +  +M K++  + Q      
Sbjct: 1720 IDDIAKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA 1774

Query: 125  AV-DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELE 180
             + D +  L+       E++ ++  +    E + +++    +   Q  KI+E   +LE E
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE 1834

Query: 181  NKELRELLSISSESLQARKENSMDTASQ 208
              +++ L     ESL +R + +M+  ++
Sbjct: 1835 RTQVKRL-----ESLASRLKENMEKLTE 1857



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 38/183 (20%), Positives = 80/183 (43%), Gaps = 26/183 (14%)

Query: 20   REHD---AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHIL 76
            RE D   A A SL  Q       +A   +   +L  +++    +++ D   ++K K    
Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK--- 1542

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDAEPVLKAH 135
                  Q+RDL+ + ++    L+E    ++++  +K R +M              + +  
Sbjct: 1543 ------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM-------------EMERMR 1583

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
            Q+HS E+ES+ + + E  +  +K ++  + Q  +  E   ++  E +EL   L+  S+ +
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643

Query: 196  QAR 198
              R
Sbjct: 1644 NRR 1646


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 42/208 (20%), Positives = 92/208 (44%), Gaps = 21/208 (10%)

Query: 8    ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQVRQRYQEDASD 64
            +L DA+ +L+ L+    +   +      L       AA  +A  A+  ++   + +    
Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQ---- 1719

Query: 65   MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 124
            + D++K K  +       Q+  LQ+E  E+   LEE Q+ +  +M K++  + Q      
Sbjct: 1720 IDDIAKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA 1774

Query: 125  AV-DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELE 180
             + D +  L+       E++ ++  +    E + +++    +   Q  KI+E   +LE E
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE 1834

Query: 181  NKELRELLSISSESLQARKENSMDTASQ 208
              +++ L     ESL +R + +M+  ++
Sbjct: 1835 RTQVKRL-----ESLASRLKENMEKLTE 1857



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 38/183 (20%), Positives = 80/183 (43%), Gaps = 26/183 (14%)

Query: 20   REHD---AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHIL 76
            RE D   A A SL  Q       +A   +   +L  +++    +++ D   ++K K    
Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK--- 1542

Query: 77   LSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDAEPVLKAH 135
                  Q+RDL+ + ++    L+E    ++++  +K R +M              + +  
Sbjct: 1543 ------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM-------------EMERMR 1583

Query: 136  QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 195
            Q+HS E+ES+ + + E  +  +K ++  + Q  +  E   ++  E +EL   L+  S+ +
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643

Query: 196  QAR 198
              R
Sbjct: 1644 NRR 1646


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 34/197 (17%)

Query: 2   SCTIEKILTDAKTLLERLR-----EHDAAAESLVDQSAALHR-RVAAMRE-AGTALPDQV 54
           +  ++++    +  LERLR      H+     L +     HR  +  +++  G     Q+
Sbjct: 608 NAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667

Query: 55  RQRYQEDASDMKDMSKYKPHILLSQ-----ENTQIRDLQQENRELWISLEEHQDALELIM 109
                E +  ++ M   K +++  Q     E ++++DLQQ                 L+ 
Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS----------------LVN 711

Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCK 169
           SK  +  LQ+   +K ++   +L+  +     +E ++  +    E++ K ++  ++    
Sbjct: 712 SKSEEMTLQINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEND--- 765

Query: 170 IQEKLAQLELENKELRE 186
           +QEK AQLE EN  L++
Sbjct: 766 LQEKFAQLEAENSILKD 782



 Score = 36.2 bits (82), Expect = 0.021
 Identities = 47/231 (20%), Positives = 100/231 (43%), Gaps = 46/231 (19%)

Query: 5    IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE---- 60
            I+++  +      RL+E +A  + + ++   L R+  AM+     +  Q+ Q  ++    
Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004

Query: 61   ------DASDMKD-------------MSKYKPHILLSQE-NTQIRDLQQENRELWISLEE 100
                   A  ++D               +    I L QE NT++ DL+Q+N+ L   LE+
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064

Query: 101  HQDAL--ELIMSKYRKQMLQLMVAK-----KAVDAEPVLKAHQSHSAE-----IESQIDR 148
             +  L  + I  ++ + + Q  + K     K V     +  HQ+   E     ++ + D+
Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124

Query: 149  ICEM---GEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQ 196
              E+    E +++ +Q       +  E++ +LE   +EL + L +S+++ Q
Sbjct: 2125 CSELLLSKEQLQRDIQ-------ERNEEIEKLEFRVRELEQALLVSADTFQ 2168



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 14/196 (7%)

Query: 6    EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65
            EK +T+ +  LE+ RE     E+  ++   LH ++   ++  T    ++ Q  +    DM
Sbjct: 2202 EKEITNLEEQLEQFREE---LENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2258

Query: 66   KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKA 125
            + +       L  +E+  +    Q+   L+    +     E+ + +  +Q+ +L    K 
Sbjct: 2259 EKLG------LAIKESDAMST--QDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKI 2310

Query: 126  VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185
                 V++       ++E+QI+ +    E +++  + + +Q  ++ EKL Q EL N  + 
Sbjct: 2311 TTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELAN--IG 2367

Query: 186  ELLSISSESLQARKEN 201
            +  S+++ SL    ++
Sbjct: 2368 QKTSMNAHSLSEEADS 2383



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 34/184 (18%), Positives = 79/184 (42%), Gaps = 31/184 (16%)

Query: 24   AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQ 83
            A   SL+ +  ALH ++   +           +R QE     +++ +Y     + Q+ +Q
Sbjct: 3085 ADRRSLLSEIQALHAQMNGRKIT--------LKREQESEKPSQELLEYN----IQQKQSQ 3132

Query: 84   IRDLQQE---NRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSA 140
            + ++Q E    ++    L+E   + ++++++ + ++     A+  ++ E  LKA   H  
Sbjct: 3133 MLEMQVELSSMKDRATELQEQLSSEKMVVAELKSEL-----AQTKLELETTLKAQHKHLK 3187

Query: 141  EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 200
            E+E+            R  V+   D+   + + LA  + +++EL+  L      L   +E
Sbjct: 3188 ELEA-----------FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEE 3236

Query: 201  NSMD 204
               +
Sbjct: 3237 RDKE 3240



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 30/150 (20%)

Query: 54   VRQRYQEDAS-DMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112
            VRQ   ++ S    D S+    ++L++E  Q+ D++QE   L    +EHQ A EL+   +
Sbjct: 1561 VRQSIHDEISVSSMDASR---QLMLNEE--QLEDMRQE---LVRQYQEHQQATELLRQAH 1612

Query: 113  RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE 172
             +QM                +  +    +++ +I R   +   + +   +D++     +E
Sbjct: 1613 MRQM----------------ERQREDQEQLQEEIKR---LNRQLAQRSSIDNENLVSERE 1653

Query: 173  KLAQLELENKELRELLSISSESLQARKENS 202
            ++   ELE   L++L     E L     NS
Sbjct: 1654 RVLLEELE--ALKQLSLAGREKLCCELRNS 1681


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 34/197 (17%)

Query: 2   SCTIEKILTDAKTLLERLR-----EHDAAAESLVDQSAALHR-RVAAMRE-AGTALPDQV 54
           +  ++++    +  LERLR      H+     L +     HR  +  +++  G     Q+
Sbjct: 608 NAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667

Query: 55  RQRYQEDASDMKDMSKYKPHILLSQ-----ENTQIRDLQQENRELWISLEEHQDALELIM 109
                E +  ++ M   K +++  Q     E ++++DLQQ                 L+ 
Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS----------------LVN 711

Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCK 169
           SK  +  LQ+   +K ++   +L+  +     +E ++  +    E++ K ++  ++    
Sbjct: 712 SKSEEMTLQINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEND--- 765

Query: 170 IQEKLAQLELENKELRE 186
           +QEK AQLE EN  L++
Sbjct: 766 LQEKFAQLEAENSILKD 782



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 50/248 (20%), Positives = 106/248 (42%), Gaps = 50/248 (20%)

Query: 5    IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE---- 60
            I+++  +      RL+E +A  + + ++   L R+  AM+     +  Q+ Q  ++    
Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004

Query: 61   ------DASDMKD-------------MSKYKPHILLSQE-NTQIRDLQQENRELWISLEE 100
                   A  ++D               +    I L QE NT++ DL+Q+N+ L   LE+
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064

Query: 101  HQDAL--ELIMSKYRKQMLQLMVAK-----KAVDAEPVLKAHQSHSAE-----IESQIDR 148
             +  L  + I  ++ + + Q  + K     K V     +  HQ+   E     ++ + D+
Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124

Query: 149  ICEM---GEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSE----SLQARKEN 201
              E+    E +++ +Q       +  E++ +LE   +EL + L +       +++A+ E 
Sbjct: 2125 CSELLLSKEQLQRDIQ-------ERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPEL 2177

Query: 202  SMDTASQA 209
            S++   QA
Sbjct: 2178 SLEVQLQA 2185



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 14/196 (7%)

Query: 6    EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDM 65
            EK +T+ +  LE+ RE     E+  ++   LH ++   ++  T    ++ Q  +    DM
Sbjct: 2194 EKEITNLEEQLEQFREE---LENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250

Query: 66   KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKA 125
            + +       L  +E+  +    Q+   L+    +     E+ + +  +Q+ +L    K 
Sbjct: 2251 EKLG------LAIKESDAMST--QDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKI 2302

Query: 126  VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 185
                 V++       ++E+QI+ +    E +++  + + +Q  ++ EKL Q EL N  + 
Sbjct: 2303 TTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELAN--IG 2359

Query: 186  ELLSISSESLQARKEN 201
            +  S+++ SL    ++
Sbjct: 2360 QKTSMNAHSLSEEADS 2375



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 34/184 (18%), Positives = 79/184 (42%), Gaps = 31/184 (16%)

Query: 24   AAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQ 83
            A   SL+ +  ALH ++   +           +R QE     +++ +Y     + Q+ +Q
Sbjct: 3077 ADRRSLLSEIQALHAQMNGRKIT--------LKREQESEKPSQELLEYN----IQQKQSQ 3124

Query: 84   IRDLQQE---NRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSA 140
            + ++Q E    ++    L+E   + ++++++ + ++     A+  ++ E  LKA   H  
Sbjct: 3125 MLEMQVELSSMKDRATELQEQLSSEKMVVAELKSEL-----AQTKLELETTLKAQHKHLK 3179

Query: 141  EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 200
            E+E+            R  V+   D+   + + LA  + +++EL+  L      L   +E
Sbjct: 3180 ELEA-----------FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEE 3228

Query: 201  NSMD 204
               +
Sbjct: 3229 RDKE 3232



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 30/150 (20%)

Query: 54   VRQRYQEDAS-DMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKY 112
            VRQ   ++ S    D S+    ++L++E  Q+ D++QE   L    +EHQ A EL+   +
Sbjct: 1561 VRQSIHDEISVSSMDASR---QLMLNEE--QLEDMRQE---LVRQYQEHQQATELLRQAH 1612

Query: 113  RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE 172
             +QM                +  +    +++ +I R   +   + +   +D++     +E
Sbjct: 1613 MRQM----------------ERQREDQEQLQEEIKR---LNRQLAQRSSIDNENLVSERE 1653

Query: 173  KLAQLELENKELRELLSISSESLQARKENS 202
            ++   ELE   L++L     E L     NS
Sbjct: 1654 RVLLEELE--ALKQLSLAGREKLCCELRNS 1681


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
            1 [Homo sapiens]
          Length = 1412

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 54/229 (23%), Positives = 103/229 (44%), Gaps = 31/229 (13%)

Query: 1    MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRV-AAMREAG---TALPDQVRQ 56
            M   ++KIL DAK  L  L    +  E L  Q+   + R  +AM ++G    A   ++ +
Sbjct: 1188 MENNVQKILLDAKPDLPTL----SRIEILAPQNGLCNARFGSAMEKSGKMDVAEALELSE 1243

Query: 57   RYQEDAS-------DMKDMSKYKPHILLS-QENTQIRDLQQENRELWIS----LEEHQDA 104
            +   D S       ++K+MS +     LS QE  ++  L+Q + +L       L+     
Sbjct: 1244 KLYLDMSKTLGSLMNIKNMSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQLKNQLGR 1303

Query: 105  LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 164
             E ++  Y K + QL  +K +++       +QS  A++E  I +  E   ++++A++  +
Sbjct: 1304 KEELLRGYEKDVEQLRRSKVSIEM------YQSQVAKLEDDIYKEAEEKALLKEALERME 1357

Query: 165  DQFCKIQEKLAQLELENKEL---RELLSISSESLQARKENSMDTASQAI 210
             Q C  QEK     +  +++   +  L +  E    RKE S  ++   +
Sbjct: 1358 HQLC--QEKRINRAIRQQKVGTRKASLKMDQEREMLRKETSSKSSQSLL 1404



 Score = 27.3 bits (59), Expect = 9.7
 Identities = 33/170 (19%), Positives = 75/170 (44%), Gaps = 23/170 (13%)

Query: 63  SDMKDMSKYKPHILLSQENTQIRDLQQENRELWIS-------------LEEHQDALELIM 109
           SD +  SKYK  I+ + +N ++ +L Q+  E   S             L+E  DA +  +
Sbjct: 241 SDYEIESKYKDVIIANLQN-EVAELSQKVSETTTSRQNEKEISQKCQVLDEDIDAKQKEI 299

Query: 110 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICE-------MGEVMRKAVQV 162
              + Q+  L      V  +  L    S    ++++ + +         M   ++K +  
Sbjct: 300 QSLKSQISALQKGYSKVLCQ-TLSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILA 358

Query: 163 DDDQFCKIQEKLAQLELENKEL-RELLSISSESLQARKENSMDTASQAIK 211
            D+Q  +++E+++ L+ +NK+   +L ++ S     ++E   + A + ++
Sbjct: 359 KDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAHRELR 408


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 7/136 (5%)

Query: 77  LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ 136
           LS    Q+R+LQ+   +L I+LE+HQD+    M K+++Q  +   A +A  AE +  A  
Sbjct: 74  LSDYAEQVRNLQKIKEKLEIALEKHQDS---SMRKFQEQN-ETFQANRAKMAEGLALALA 129

Query: 137 SHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQL-ELENKELRELLSISSESL 195
               E   ++D++ +   ++   +Q   +Q   + ++  ++ ELE  + +EL  I  + +
Sbjct: 130 RKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKI--KHM 187

Query: 196 QARKENSMDTASQAIK 211
             +KE S+    Q ++
Sbjct: 188 LLKKEESLGKMEQELE 203


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 34/153 (22%), Positives = 71/153 (46%), Gaps = 18/153 (11%)

Query: 53  QVRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALEL----I 108
           ++ + ++ED  + K+  K +       E       ++E    +I  +E+  +  L    +
Sbjct: 842 EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDV 901

Query: 109 MSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFC 168
           +S +R+   Q  +A+K ++A  V++  Q    E+E++           R+A +  +D + 
Sbjct: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA----------RQAEEKFEDAY- 950

Query: 169 KIQEKLAQLELENKELRELLSISSESLQARKEN 201
              EKL    ++NK+L EL+  S +  +  KEN
Sbjct: 951 ---EKLHHTLIKNKDLEELVMTSRKESKEEKEN 980


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.125    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,281,224
Number of Sequences: 37866
Number of extensions: 232781
Number of successful extensions: 1970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 303
Number of HSP's that attempted gapping in prelim test: 1449
Number of HSP's gapped (non-prelim): 749
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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