BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156104903 myomesin 2 [Homo sapiens] (1465 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156104903 myomesin 2 [Homo sapiens] 2974 0.0 gi|140560917 myomesin 1 isoform b [Homo sapiens] 1341 0.0 gi|155969693 myomesin family, member 3 [Homo sapiens] 1118 0.0 gi|140560919 myomesin 1 isoform a [Homo sapiens] 862 0.0 gi|110349719 titin isoform N2-A [Homo sapiens] 269 1e-71 gi|110349717 titin isoform novex-2 [Homo sapiens] 269 1e-71 gi|110349713 titin isoform novex-1 [Homo sapiens] 269 1e-71 gi|110349715 titin isoform N2-B [Homo sapiens] 269 1e-71 gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 168 3e-41 gi|148839296 immunoglobulin-like and fibronectin type III domain... 154 8e-37 gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 137 8e-32 gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 137 8e-32 gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 137 8e-32 gi|133908641 myosin binding protein C, fast type [Homo sapiens] 132 2e-30 gi|222352127 sidekick 2 [Homo sapiens] 129 3e-29 gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 126 1e-28 gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 125 3e-28 gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 110 8e-24 gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 110 8e-24 gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 107 1e-22 gi|224994173 roundabout 1 isoform d [Homo sapiens] 101 5e-21 gi|224994171 roundabout 1 isoform c [Homo sapiens] 101 5e-21 gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 101 5e-21 gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 101 5e-21 gi|119220552 sidekick 1 [Homo sapiens] 100 1e-20 gi|19743806 roundabout 1 isoform b [Homo sapiens] 100 2e-20 gi|4506569 roundabout 1 isoform a [Homo sapiens] 100 2e-20 gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 97 1e-19 gi|157311649 neogenin homolog 1 [Homo sapiens] 97 1e-19 gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 92 3e-18 >gi|156104903 myomesin 2 [Homo sapiens] Length = 1465 Score = 2974 bits (7709), Expect = 0.0 Identities = 1465/1465 (100%), Positives = 1465/1465 (100%) Query: 1 MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQ 60 MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQ Sbjct: 1 MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQ 60 Query: 61 TSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARS 120 TSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARS Sbjct: 61 TSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARS 120 Query: 121 QARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGF 180 QARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGF Sbjct: 121 QARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGF 180 Query: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST Sbjct: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 Query: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT Sbjct: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 Query: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR 360 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR Sbjct: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR 360 Query: 361 GGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 GGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD Sbjct: 361 GGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 Query: 421 RCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDP 480 RCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDP Sbjct: 421 RCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDP 480 Query: 481 LDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKD 540 LDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKD Sbjct: 481 LDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKD 540 Query: 541 PLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 PLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT Sbjct: 541 PLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 Query: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN Sbjct: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL Sbjct: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL Sbjct: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG Sbjct: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD Sbjct: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 Query: 901 TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIET Sbjct: 901 TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS Sbjct: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 Query: 1021 ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRF 1080 ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRF Sbjct: 1021 ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRF 1080 Query: 1081 SIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDV 1140 SIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDV Sbjct: 1081 SIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDV 1140 Query: 1141 TEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKA 1200 TEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKA Sbjct: 1141 TEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKA 1200 Query: 1201 TLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEM 1260 TLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEM Sbjct: 1201 TLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEM 1260 Query: 1261 KVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSG 1320 KVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSG Sbjct: 1261 KVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSG 1320 Query: 1321 QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK 1380 QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK Sbjct: 1321 QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK 1380 Query: 1381 NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGE 1440 NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGE Sbjct: 1381 NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGE 1440 Query: 1441 KIPDMAPPQQAKPKLIPASASAAGQ 1465 KIPDMAPPQQAKPKLIPASASAAGQ Sbjct: 1441 KIPDMAPPQQAKPKLIPASASAAGQ 1465 >gi|140560917 myomesin 1 isoform b [Homo sapiens] Length = 1589 Score = 1341 bits (3470), Expect = 0.0 Identities = 676/1446 (46%), Positives = 950/1446 (65%), Gaps = 30/1446 (2%) Query: 6 VPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGG 65 VP + R +H + R + E A+ +S++ ++ S AS QT+ Sbjct: 138 VPIFSGRQKHVSGITDTEEER--IKEAAAYIAQRNLLASEEGITT-SKQSTASKQTT--- 191 Query: 66 TICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHL---EEDVHLARSQA 122 S Q +++ + QS + A RQ +S+ A +E+ +S+ Sbjct: 192 ---------ASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRK 242 Query: 123 ---RDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQG 179 R+K ++ ++++ +E+ + E+ + APE +++ RSHTVWE+ +VKL ++ G Sbjct: 243 VVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAG 302 Query: 180 FPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVS 239 +P P V WYK+ I A PGKY IES YG+HTLEIN DF+DTA Y A A N G++S Sbjct: 303 WPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELS 362 Query: 240 TNAAVVVRRFRGDEEPFRSVGLPIGLPLS-SMIPY---THFDVQFLEKFGVTFRREGETV 295 A+VVV+R++G+ + R +PLS + PY + F++ F +KF V+F REGET+ Sbjct: 363 AYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETM 422 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTL 355 +L C +++TP++K QP +WYR+ V L SKW + + +A+L+FSHL+K+DEGLYT+ Sbjct: 423 SLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTI 482 Query: 356 RIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 R+ +SA++FVRDAD + GAP AP+D++C +AN+DY+I++WK P SP++ Sbjct: 483 RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAV 475 GYF+D+CEVGT++W QCND PVK ++PVTGL EGRSYIFRVRAVN GI PSRVS+ V Sbjct: 543 GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602 Query: 476 AALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT 535 AALDP + RL++ I ++ + VPGPPT + +E +R+YVVLSW+PP Sbjct: 603 AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662 Query: 536 PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSE 595 RG + +MYF+EK G+ +WQRVN + V+SPR+A+FDL EGKSY FRV +N G+ E Sbjct: 663 QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGE 722 Query: 596 PSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNL 655 PSE T D +P APG+++ SRNT TSVVV W+ K ++L+GYY++ VAG+ Sbjct: 723 PSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK 782 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY 715 WEPCN+ P+ +RF HGL TG+ YIFRV+AVNA G+SE SQ+S+ I+V+AA+ PS P Sbjct: 783 WEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPC 842 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHK---NWHEVNSSPSKPTILTV 772 IT L SM LGWK P GG+ I GYY++ REV W E N + Sbjct: 843 DITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKI 902 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVML 832 L E +Y+F++AA+N+AG+G PS SE FKCE WT+ PGP + L EVR SLV+ Sbjct: 903 SNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQ 962 Query: 833 WKAPVYSGSSPVSGYFVDFREEDAGE--WITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 WK PV+SG +PV+GYFVD +E A E W +N+ N YLKV L++G +YVFRVRA+ Sbjct: 963 WKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1022 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEI 950 N GVGKPSD + PV+ E RPGTKE+ VD+ G I L F+C +MT S+F+W K Y Sbjct: 1023 NQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVST 1082 Query: 951 SDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNE 1010 D R ++E+ G+ +K+ K+ +DLG YS V+DTDG++SS+++D EEL+RL+ALS+E Sbjct: 1083 EDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHE 1142 Query: 1011 IKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKAT 1070 K PT+P+KSELA EI +KG+VRFW+QAE LS +A +I N++E+ + +++ D+ T Sbjct: 1143 HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1202 Query: 1071 GIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGP 1130 GIIEM M++ E+EGTYT Q+ DGKA + S++VL+GD FK + +EAEFQR+E++RKQGP Sbjct: 1203 GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1262 Query: 1131 HFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKL 1190 HF EYL W+VT EC V L CKVAN KKET W KD+ + + + GIC LLI + Sbjct: 1263 HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1322 Query: 1191 SKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQ 1250 SKKD G Y+ LKDDRG+D S L++ + + ++++ + + SA+ LK+ T EGI+L Sbjct: 1323 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1382 Query: 1251 CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKD 1310 F+ Y+ +++KVNW H + I S+ ++ G + E WLQI EPT DKGKY E+FDGK Sbjct: 1383 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1442 Query: 1311 NHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFG 1370 HQ+++DLSGQA+DEA+AEFQ+ K AA AEKNR R++GGLPDVVTI EGK LNLTC V+G Sbjct: 1443 GHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWG 1502 Query: 1371 NPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKID 1430 +P PEV W KN++ + +H ++K E + TI GV++ DSGKY + +KNKYG E D Sbjct: 1503 DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSD 1562 Query: 1431 VTVSVY 1436 TVSV+ Sbjct: 1563 FTVSVF 1568 Score = 46.2 bits (108), Expect = 2e-04 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 18/87 (20%) Query: 4 VTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKR-------ASTQASSQKSLSQR----- 51 +++PFYQ+ H+H+D SYRN R + Y +K+ ST SS+ S + R Sbjct: 1 MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60 Query: 52 ------SSSQRASSQTSLGGTICRVCA 72 SSSQ+ +SQ +L + R A Sbjct: 61 FRRASASSSQQQASQHALSSEVSRKAA 87 >gi|155969693 myomesin family, member 3 [Homo sapiens] Length = 1437 Score = 1118 bits (2892), Expect = 0.0 Identities = 600/1420 (42%), Positives = 860/1420 (60%), Gaps = 27/1420 (1%) Query: 30 DEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRY 89 +E +++ S + S SS+ ++ + A S++ E + R + Sbjct: 30 EEQKEERQHSLRMGSSVRRRTFRSSEEEHEFSAADYALAAALALTASSELSWEAQLRRQT 89 Query: 90 QSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEER 149 ++ KR F ++ E R + D +++ E+K+ + E Sbjct: 90 SAVELEERGQKRVGFGNDWERTEIAFLQTHRLLRQRRDWKTLRRRTEEKVQEAKELRELC 149 Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLIC-QAAEPGKYRIESN 208 R P + LRSH VWE +V L TVQ P P V WYK+ + I + GKYRI +N Sbjct: 150 YGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNN 209 Query: 209 YGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS 268 YG+ +LEI R +D+ATY+ NAHGQ S+ A V+VR + G + F S S Sbjct: 210 YGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFK----RS 265 Query: 269 SMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 + P V+F F RE E +L C L + D+ + +W+RD LL+ S+ Sbjct: 266 TFGP----SVEFTSVLKPVFAREKEPFSLSC--LFSEDVLDAES-IQWFRDGSLLRSSRR 318 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMD 388 K+ + + QASL S +K+DEGLY +R+ S G + S ++ VRDA+ GAPG+P++ Sbjct: 319 RKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLN 378 Query: 389 LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLF 448 ++C D NRD +I+TW PP+ T +P+ Y ++RC+ + W+ C++AP C+ P+ GL Sbjct: 379 VRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLV 438 Query: 449 EGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDA 508 EG+SY FRVRA++ G S PS+ S+ V D RR + + +I I D E Sbjct: 439 EGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDAFEDTV 498 Query: 509 QVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSP 568 +P PPT VHASEI YVVL+WE P+PR + PL Y +EKSV+GSG+W+ +++++ VRSP Sbjct: 499 TIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAISSESPVRSP 558 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628 R+AV DL + KSYVFRV + N++GLS+PSE + PI + P +V A R+T+TSV Sbjct: 559 RFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSV 618 Query: 629 VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 + WD P + +LLGYY+ GT+ W+ N+KPI RF V GL TG++Y F V++V+ Sbjct: 619 SLTWD-PVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVS 677 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G+ E+S ++ I+V+ AL PS PYG LLNC + M +GWK PK GG ILGY+LD Sbjct: 678 EAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLD 737 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 + + +WH VN P + V L EG YEF+ A N AG+GE S PS F+C+ W Sbjct: 738 QHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEW 797 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 TMP+PGP YD+ EVR TSLV+ W+ P+Y G+ PV+GY V F+EE + +W V + Sbjct: 798 TMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPIS 857 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYL 928 +L+VSDLQ GK+YVF+V+A+N+ G+G+PS ++PVL+E +PG EI GVDE+G IYL Sbjct: 858 GTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGFIYL 917 Query: 929 GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 F+ E D+S+F W K Y+ D +R KIE + SK+ LK P EDLGTYSV V+D D Sbjct: 918 AFEAPEAPDSSEFQWSKDYKGPLDPQRVKIEDKVNKSKVILKEPGLEDLGTYSVIVTDAD 977 Query: 989 -GVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASY 1047 +S+S L EELE+L LS+EI+NP I L S +I ++G VR WL+ E LSP A Sbjct: 978 EDISASHTLTEEELEKLKKLSHEIRNPVIKLISGWNIDILERGEVRLWLEVEKLSPAAEL 1037 Query: 1048 RFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIG 1107 I N++E+ S +I D+ G++E+++ S E++G+YT Q+ DGKAK+Q +L L+ Sbjct: 1038 HLIFNNKEIFSSPNRKINFDREKGLVEVIIQNLSEEDKGSYTAQLQDGKAKNQITLTLVD 1097 Query: 1108 DAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL--- 1164 D F +L +A+ +R+++ RKQGP+F L W VTE+C+V+L CKV NTKKET F+W Sbjct: 1098 DDFDKLLRKADAKRRDWKRKQGPYFERPLQWKVTEDCQVQLTCKVTNTKKETRFQWFFQR 1157 Query: 1165 --KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDD 1222 D Y+ ET G L I +LSKKD G Y+A + DDRG+D +IL++ G D Sbjct: 1158 AEMPDGQYDPET------GTGLLCIEELSKKDKGIYRAMVSDDRGEDDTILDLTGDALDA 1211 Query: 1223 MILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDE-MKVNWCHKDAKISSSEHMRIGG 1281 + + R+ SA+PLK+ T EGIR+ +KY+ E MK W HKD ++ S + +R G Sbjct: 1212 IFTELGRIGALSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGT 1271 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + + WL I +P + DKGKYT EI GK+ Q S DLSGQAF++A AE Q+ K A EK Sbjct: 1272 TLDEIWLHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEK 1331 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV 1401 NR +++ GLPDV TIME KTL LTC V G+P PE+ W KNDQ + + + ++V + V Sbjct: 1332 NRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTE-V 1390 Query: 1402 SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEK 1441 ++TI+ V SEDSG+Y + +KNKYG E VT+SV+KHG++ Sbjct: 1391 TITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDE 1430 >gi|140560919 myomesin 1 isoform a [Homo sapiens] Length = 1685 Score = 862 bits (2228), Expect = 0.0 Identities = 469/1084 (43%), Positives = 652/1084 (60%), Gaps = 61/1084 (5%) Query: 370 LFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNW 429 + V + +P PG P DL +A R YV+++WKPP +M YFV++CE GT NW Sbjct: 625 IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENW 683 Query: 430 VQCN-DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488 + N + PVK ++ + L EG+SY FRVR NSAG+ PS ++ D LD Sbjct: 684 QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD------ 737 Query: 489 VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEK 548 +P P + S + VV+SWE + K+ + Y+IE Sbjct: 738 ---------------------IPKAPGKIIPSRNTDTSVVVSWEE-SKDAKELVGYYIEA 775 Query: 549 SVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-- 606 SV GSG W+ N V+ R+ L+ G+SY+FRV + N GLSE S+ + I+ + Sbjct: 776 SVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAA 834 Query: 607 -------DVT-VVPSAPGRVLASRNTKTSVVVQWDRPKHEED-LLGYYVDCCVAGTNLWE 657 DV + PG + ASR V + P ++D LLG + Sbjct: 835 IGGGVSPDVCPALSDEPGGLTASRGR----VHEASPPTFQKDALLGSKPNKPSL------ 884 Query: 658 PCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI 717 P + + +G T E+ + G S+ SD +K + PS P I Sbjct: 885 PSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSK----SDPLKKKTDRAPPSPPCDI 940 Query: 718 TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHK---NWHEVNSSPSKPTILTVDG 774 T L SM LGWK P GG+ I GYY++ REV W E N + Sbjct: 941 TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 L E +Y+F++AA+N+AG+G PS SE FKCE WT+ PGP + L EVR SLV+ WK Sbjct: 1001 LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060 Query: 835 APVYSGSSPVSGYFVDFREEDAGE--WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNA 892 PV+SG +PV+GYFVD +E A E W +N+ N YLKV L++G +YVFRVRA+N Sbjct: 1061 PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120 Query: 893 NGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 GVGKPSD + PV+ E RPGTKE+ VD+ G I L F+C +MT S+F+W K Y D Sbjct: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 R ++E+ G+ +K+ K+ +DLG YS V+DTDG++SS+++D EEL+RL+ALS+E K Sbjct: 1181 SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHK 1240 Query: 1013 NPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 PT+P+KSELA EI +KG+VRFW+QAE LS +A +I N++E+ + +++ D+ TGI Sbjct: 1241 FPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGI 1300 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 IEM M++ E+EGTYT Q+ DGKA + S++VL+GD FK + +EAEFQR+E++RKQGPHF Sbjct: 1301 IEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHF 1360 Query: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSK 1192 EYL W+VT EC V L CKVAN KKET W KD+ + + + GIC LLI + SK Sbjct: 1361 VEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSK 1420 Query: 1193 KDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCF 1252 KD G Y+ LKDDRG+D S L++ + + ++++ + + SA+ LK+ T EGI+L F Sbjct: 1421 KDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSF 1480 Query: 1253 MKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNH 1312 + Y+ +++KVNW H + I S+ ++ G + E WLQI EPT DKGKY E+FDGK H Sbjct: 1481 VTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGH 1540 Query: 1313 QRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNP 1372 Q+++DLSGQA+DEA+AEFQ+ K AA AEKNR R++GGLPDVVTI EGK LNLTC V+G+P Sbjct: 1541 QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600 Query: 1373 DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVT 1432 PEV W KN++ + +H ++K E + TI GV++ DSGKY + +KNKYG E D T Sbjct: 1601 PPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFT 1660 Query: 1433 VSVY 1436 VSV+ Sbjct: 1661 VSVF 1664 Score = 667 bits (1720), Expect = 0.0 Identities = 465/1502 (30%), Positives = 750/1502 (49%), Gaps = 131/1502 (8%) Query: 6 VPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGG 65 VP + R +H + R + E A+ +S++ ++ S AS QT+ Sbjct: 138 VPIFSGRQKHVSGITDTEEER--IKEAAAYIAQRNLLASEEGITT-SKQSTASKQTT--- 191 Query: 66 TICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHL---EEDVHLARSQA 122 S Q +++ + QS + A RQ +S+ A +E+ +S+ Sbjct: 192 ---------ASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRK 242 Query: 123 ---RDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQG 179 R+K ++ ++++ +E+ + E+ + APE +++ RSHTVWE+ +VKL ++ G Sbjct: 243 VVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAG 302 Query: 180 FPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVS 239 +P P V WYK+ I A PGKY IES YG+HTLEIN DF+DTA Y A A N G++S Sbjct: 303 WPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELS 362 Query: 240 TNAAVVVRRFRGDEEPFRSVGLPIGLPLS-SMIPY---THFDVQFLEKFGVTFRREGETV 295 A+VVV+R++G+ + R +PLS + PY + F++ F +KF V+F REGET+ Sbjct: 363 AYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETM 422 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTL 355 +L C +++TP++K QP +WYR+ V L SKW + + +A+L+FSHL+K+DEGLYT+ Sbjct: 423 SLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTI 482 Query: 356 RIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 R+ +SA++FVRDAD + GAP AP+D++C +AN+DY+I++WK P SP++ Sbjct: 483 RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAV 475 GYF+D+CEVGT++W QCND PVK ++PVTGL EGRSYIFRVRAVN GI PSRVS+ V Sbjct: 543 GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602 Query: 476 AALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT 535 AALDP + RL++ I ++ + VPGPPT + +E +R+YVVLSW+PP Sbjct: 603 AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662 Query: 536 PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSE 595 RG + +MYF+EK G+ +WQRVN + V+SPR+A+FDL EGKSY FRV +N G+ E Sbjct: 663 QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGE 722 Query: 596 PSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNL 655 PSE T D +P APG+++ SRNT TSVVV W+ K ++L+GYY++ VAG+ Sbjct: 723 PSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK 782 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAAL------- 708 WEPCN+ P+ +RF HGL TG+ YIFRV+AVNA G+SE SQ+S+ I+V+AA+ Sbjct: 783 WEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPD 842 Query: 709 ---TVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPS 765 + P G+T H + P +LG S P+ Sbjct: 843 VCPALSDEPGGLTASRGRVHEAS-----PPTFQKDALLG-----------------SKPN 880 Query: 766 KPTILTVD---GLTEGS----LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818 KP++ + G TE S + ++ + S+ K + P P P D Sbjct: 881 KPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP-PSPPCD 939 Query: 819 LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE---EDAGEWITVNQTTTANRYLKVS 875 +T E S+V+ WK P G + ++GY+V++RE G+W N + K+S Sbjct: 940 ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS 999 Query: 876 DLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----ARPG-TKEISAGVDEQGNIYLGF 930 +L++ Y F+V A+N G+G PS SE E A PG + + ++ L + Sbjct: 1000 NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW 1059 Query: 931 DCQEMTDASQFT--WCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 + + T + E + +++++ +YLK ++ +Y V Sbjct: 1060 KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVR--- 1116 Query: 989 GVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYR 1048 ++ + V P + L+ + T P E+ + D G + + + ++P + + Sbjct: 1117 AINQAGVGKPSD------LAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFS 1170 Query: 1049 FIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGD 1108 + + VS + R++ + +M +++ G Y+ + D + S L+ Sbjct: 1171 W--SKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLI---- 1224 Query: 1109 AFKTVLEEAEFQRKEFLRKQGPH----FAEYLHWDVTEECEVRLVCKV----ANTKKETV 1160 +E E +R L + L ++ E+ +VR + N K + Sbjct: 1225 ------DEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYI 1278 Query: 1161 FKWLKDDVLYETETLPNLER--GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218 F + ++ + +++R GI E+ + KL +D G Y L+D + + S + + G Sbjct: 1279 FN--EKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGD 1336 Query: 1219 VYDDMILA--------MSRVCGKSASPLKVLCTPE-GIRLQCFMKYFTDEMKVNWCHKDA 1269 V+ + + + L T E + L+C + E + W + Sbjct: 1337 VFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDER 1396 Query: 1270 KISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAE 1329 +IS E + + + L I E ++KD G Y + D + + L L +AF E E Sbjct: 1397 EISVDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454 Query: 1330 FQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE 1389 + A + + + + EG L T + D +V W N I+ S+ Sbjct: 1455 VCKKIALSATDLK----------IQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSD 1503 Query: 1390 HFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQ 1449 V + + + I T D GKY + + + G + V +S + E + + Sbjct: 1504 RVKTGV-TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLK 1562 Query: 1450 QA 1451 QA Sbjct: 1563 QA 1564 Score = 46.2 bits (108), Expect = 2e-04 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 18/87 (20%) Query: 4 VTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKR-------ASTQASSQKSLSQR----- 51 +++PFYQ+ H+H+D SYRN R + Y +K+ ST SS+ S + R Sbjct: 1 MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60 Query: 52 ------SSSQRASSQTSLGGTICRVCA 72 SSSQ+ +SQ +L + R A Sbjct: 61 FRRASASSSQQQASQHALSSEVSRKAA 87 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 269 bits (688), Expect = 1e-71 Identities = 229/865 (26%), Positives = 373/865 (43%), Gaps = 101/865 (11%) Query: 153 APEILVRLR---SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 APEI + ++ TV ++L TV G P P + W K ++ Q + IE+ Sbjct: 13687 APEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK---RITIENVP 13743 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 T+ I + DT TY A N G+ + V V L Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV--------------------LDK 13783 Query: 270 MIPYTHFDVQFL--EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK 327 P FD+ + E +T+ + K T V +R W++ +K++ Sbjct: 13784 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE--RRATDSEVWHKLSSTVKDTN 13841 Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAP 383 + + L + E ++ + + GV + A P+ P Sbjct: 13842 FKA------------TKLIPNKEYIFRVAAENMYGVGEPV------QASPITAKYQFDPP 13883 Query: 384 GAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYP 443 G P L+ D +D V +TW P+ SP+ GY+V+R + T+ WV+CN PVK Y Sbjct: 13884 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYR 13943 Query: 444 VTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD 503 V GL + Y FRV A N AG +PS+ ++ + DP+D Sbjct: 13944 VKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID--------------------- 13982 Query: 504 LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVGSGSWQRVNAQ 562 P PP ++ + V L+W P G + Y IE G+ W RV Sbjct: 13983 ------PPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV--A 14034 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 V + ++ + LMEG+ Y FRV + N+ G SEPSE + P+ ++ PS P + Sbjct: 14035 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 14094 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 TK + ++W P+ + + Y V+ W+ + + + V LT G Y Sbjct: 14095 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVD-TTVKDTKCTVTPLTEGSLY 14153 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 +FRV A NA+G S+ ++ D + + T P PY + +++ + L W+ PK GG Sbjct: 14154 VFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGR 14213 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PI Y ++K+E W + + V + EG+ +F++ A N AG+G PS+P+ Sbjct: 14214 PIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT 14273 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 E E T P P P DL + + + WK P +G SP+ GY V+ +W+ Sbjct: 14274 EILSIEDPTSP-PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWM 14332 Query: 861 TVNQTTTANRYLKVSD-LQQGKTYVFRVRAVNANGVGKPSDTSEPVLV---EARP----G 912 VN + KV + + K YV RVRAVNA GV +PS+ SE V+ + +P Sbjct: 14333 RVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE 14392 Query: 913 TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 T +I E+ +I + F + S W K +E+ +R ++ DH +L+ P Sbjct: 14393 THDIIVIEGEKLSIPVPFRAVPVPTVS---WHKDGKEVKASDRLTMK--NDHISAHLEVP 14447 Query: 973 D--KEDLGTYSVSVSDTDGVSSSFV 995 + D G Y++++ + G +++ + Sbjct: 14448 KSVRADAGIYTITLENKLGSATASI 14472 Score = 268 bits (685), Expect = 3e-71 Identities = 209/769 (27%), Positives = 337/769 (43%), Gaps = 83/769 (10%) Query: 272 PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM 331 P DV+ L V + G + L T+ P+ P+ W + D++LK+ K + Sbjct: 13688 PEIFLDVKLLAGLTV---KAGTKIELPATVTGKPE-----PKITWTKADMILKQDKRITI 13739 Query: 332 FFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 +++++ + D G Y + V+ G + + V D PG P Sbjct: 13740 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK-------PGPPAAFDI 13792 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 D + ++TW PP S + Y V+R + W + + + VK + T L + Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNK 13851 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 YIFRV A N G+ P + S A YQ D P Sbjct: 13852 EYIFRVAAENMYGVGEPVQASPITAK----------------------YQFD------PP 13883 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 GPPT + S+I+++ V L+W P G P+ Y++E+ + W R N + V+ Y Sbjct: 13884 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN-KMPVKDTTY 13942 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L K Y FRVL+ N G +PS+ T PI +D P PG+ KTSV + Sbjct: 13943 RVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRL 14002 Query: 631 QWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 W +P+H+ + Y ++ GT+ W + + + ++ GL G++Y FRV+AVN Sbjct: 14003 NWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVN 14061 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G SE S+ SD + + L PS P + ++N ++ L W VP+ GGSPI Y ++ Sbjct: 14062 KAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE 14121 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+V K W V+++ K T TV LTEGSLY F++AA N G + ++ + + Sbjct: 14122 KRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD- 14179 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 T PGP Y L +V + + W+ P G P+ Y ++ +E W+ +T Sbjct: 14180 TFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGP 14239 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNI 926 + +V+D+ +G F+VRA N GVG PS+ +E + +E P + + V + G Sbjct: 14240 DCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRK 14299 Query: 927 YLGFDCQ---------------EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 ++ + EM W + D +FK+E Sbjct: 14300 HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG--------VV 14351 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 PDKE Y + V + + V +P E+ + + PTI L++ Sbjct: 14352 PDKE----YVLRVRAVNAIG---VSEPSEISENVVAKDPDCKPTIDLET 14393 Score = 231 bits (588), Expect = 5e-60 Identities = 228/871 (26%), Positives = 358/871 (41%), Gaps = 147/871 (16%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 TV +V L TV G P P V W KDG+L+ + AE K ++ N + TLE+ + D Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLL-KPAEGIKMAMQRN--LCTLELFSVNRKD 19362 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y+ A N+ G S + V ++P G P + ++ M + ++ Sbjct: 19363 SGDYTITAENSSGSKSATIKLKVL-----DKP----GPPASVKINKM---------YSDR 19404 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 +++ E + T + + +P W ++ S S Sbjct: 19405 AMLSWEPPLEDGGSEITNYIVDKRETSRPN--------------WAQVSATVPITSCSVE 19450 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA------DPLVTGAPGAPMDLQCHDANRD 397 L + E + + ++ GV D +F A DP PG + +D Sbjct: 19451 KLIEGHEYQFRICAENKYGVGDP---VFTEPAIAKNPYDP-----PGRCDPPVISNITKD 19502 Query: 398 YVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRV 457 ++ V+WKPP SP+ GY +++ E NW + N P+ TGL EG Y FRV Sbjct: 19503 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 19562 Query: 458 RAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGV 517 A+N AG +PS S A A DP PGPP Sbjct: 19563 TAINKAGPGKPSDASKAAYARDP---------------------------QYPPGPPAFP 19595 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM 576 + +R+ V LSW P G P++ Y +E S +W R N ++ R+ V LM Sbjct: 19596 KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLM 19655 Query: 577 EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV------- 629 E Y FRV + N+ G S+PS++ +D+ + P L + KT ++ Sbjct: 19656 EDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGE---LDADLRKTLILRAGVTMR 19712 Query: 630 ------------VQWDRPK-HEEDLLGYYVDCCVAGTNL-WEPCNHKPIGYNRFVVHGLT 675 + W +P + D +G + T L E N G Sbjct: 19713 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG---------- 19762 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +YI ++ N+ G E + V+KV L P P +T+ S + W+ P Sbjct: 19763 ---KYILTLE--NSCGKKEYTI---VVKV---LDTPGPPVNVTVKEISKDSAYVTWEPPI 19811 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGSPI+ Y + KR+ K+W V + SK T V L EG Y F++ A N GIG+ Sbjct: 19812 IDGGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGD 19870 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + K PGP DL V +S + WK P G S + GY VDF E+ Sbjct: 19871 PGETRDAVKAS----QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEE 19926 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKE 915 +W V ++ + K DL +GK Y FRV A N NG G PS+ + V AR Sbjct: 19927 -NKWQRVMKSLSLQYSAK--DLTEGKEYTFRVSAENENGEGTPSE----ITVVARDDV-- 19977 Query: 916 ISAGVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDH 964 ++ +D +G L + +E ++ A +W K + ++ D R +E+ + Sbjct: 19978 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 20037 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + L + + K D G Y++++ + G + Sbjct: 20038 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 20068 Score = 226 bits (575), Expect = 2e-58 Identities = 233/937 (24%), Positives = 390/937 (41%), Gaps = 106/937 (11%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E++S+ + F + P P V W+KDG + + +++++ LE+ ++ D Sbjct: 14402 EKLSIPVPF--RAVPVPTVSWHKDGK---EVKASDRLTMKNDHISAHLEVPKSVRADAGI 14456 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGV 286 Y+ N G + + V V IGLP P + K Sbjct: 14457 YTITLENKLGSATASINVKV----------------IGLPG----PCKDIKASDITKSSC 14496 Query: 287 TFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLH 346 E TP L V R E R + + GE + S + L Sbjct: 14497 KLTWEPPEFDGG-----TPILHYVLERREAGR-------RTYIPVMSGENKLSWTVKDLI 14544 Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANRDYVIVT 402 + E + ++ V++ G + ++ +P++ P P+D++ H+ + + +T Sbjct: 14545 PNGEYFFRVKAVNKVGGGE-----YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 14599 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 WKPP S +MGY +++ G W +CN+ V I Y GL EG+ Y FRVRA N+ Sbjct: 14600 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 14659 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPP----TGVH 518 AGIS PSR + A+DP+D + V L E+ D++ DA + G P T + Sbjct: 14660 AGISEPSRATPPTKAVDPIDAPK---VILRTSLEVK-RGDEIALDASISGSPYPTITWIK 14715 Query: 519 ASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSP-RYAVFDLME 577 + + P R + + E V+ QR++ + + + V D + Sbjct: 14716 DENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT--QRLSIDNSKKGESQLRVRDSLR 14773 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 ++ + N HG+++ S + P P + KTSV+ +W+ P Sbjct: 14774 PDHGLYMIKVENDHGIAKAPCTVSVLDT------PGPPINFVFEDIRKTSVLCKWEPPLD 14827 Query: 638 E--EDLLGYYVDCCVAGTNLWEPCNH-----KPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + +++ Y ++ + +P + + + ++ V L G++Y+FRV+A N Sbjct: 14828 DGGSEIINYTLE----KKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 14883 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKR 750 G ++ + P P + + +SM + W PK GSPILGY+L+KR Sbjct: 14884 GPGPPCVSKPLV-AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKR 14941 Query: 751 EVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTM 810 EV+ +W VN S VDGL EG Y F++ A N AG G+ S PS+ K + Sbjct: 14942 EVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP-KTAHDPI 15000 Query: 811 PEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR 870 PGP + T++ + W+ P ++G + GYFVD + EW + R Sbjct: 15001 SPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVR 15059 Query: 871 YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 V ++++G Y RV AVNA G G P +T +PV V + V +G I + Sbjct: 15060 QYTVKEIREGADYKLRVSAVNAAGEGPPGET-QPVTVAEPQEPPAVELDVSVKGGIQIMA 15118 Query: 931 DCQEMTDA-------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 A W K E+ D +R I+ VG S+L +K+ ++D G Y ++ Sbjct: 15119 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 15177 Query: 984 VSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 +++ G S F E+ ++ P + LK + K + W E Sbjct: 15178 ATNSCG--SKFAAARVEV-------FDVPGPVLDLKPVVTNR---KMCLLNWSDPEDDGG 15225 Query: 1044 DASYRFIINDREV------SDSEIHRIKCDKATGIIE 1074 FII ++ E R KCD TG++E Sbjct: 15226 SEITGFIIERKDAKMHTWRQPIETERSKCD-ITGLLE 15261 Score = 218 bits (554), Expect = 4e-56 Identities = 194/813 (23%), Positives = 330/813 (40%), Gaps = 104/813 (12%) Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPM 387 WT + SL + L + +E ++ + V++ GV + V +P V PG P Sbjct: 23766 WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVL--PGPPK 23823 Query: 388 DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGL 447 L+ + +D + V W P++ S ++GY V++ + W++CN + + VTGL Sbjct: 23824 SLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGL 23883 Query: 448 FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD 507 E Y FRV A N+AG+ PS + A DP+ Sbjct: 23884 TEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFK------------------------ 23919 Query: 508 AQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566 PGPPT H + ++N + L+W P G + L Y +E WQ V QT +R Sbjct: 23920 ---PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLR 23976 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD----------------VTV 610 R+ + L E + Y RV + N+ GL E + + ++ +D + V Sbjct: 23977 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 24036 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 R+ + + + W R + G + D K + Y + Sbjct: 24037 RAGGSARIHIPFKGRPTPEITWSREE------GEFTDKVQI---------EKGVNYTQLS 24081 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 + + + +K N+ G +S + V+ L P P + + S L Sbjct: 24082 IDNCDRNDAGKYILKLENSSG-----SKSAFVTVKV-LDTPGPPQNLAVKEVRKDSAFLV 24135 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W+ P GG+ + Y +DKRE K + V+S SK T V+ LTEG++Y F++ A N Sbjct: 24136 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAENE 24194 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 G+G P + + K P P +T +V TS ++W+ P + G S V GY V+ Sbjct: 24195 FGVGVPVETVDAVKAAE----PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 24250 Query: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE-- 908 + + +W V ++ N V+ L G+ Y FRV+A N G P PV+ + Sbjct: 24251 MQPKGTEKWSIVAESKVCNAV--VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 24308 Query: 909 -ARPGTK------EISAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 +P K I AG D + I +G +W K E + R +E Sbjct: 24309 TIQPSLKLPFNTYSIQAGEDLKIEIPVIG------RPRPNISWVKDGEPLKQTTRVNVEE 24362 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTI-PLK 1019 + L++K +K+D G Y+V+ +++ G ++ E L + E P + P++ Sbjct: 24363 TATSTVLHIKEGNKDDFGKYTVTATNSAGTAT---------ENLSVIVLEKPGPPVGPVR 24413 Query: 1020 SELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDR 1079 + E+ V W + +I+ R+ + + H + A I++ + Sbjct: 24414 FD---EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 24470 Query: 1080 FSIENEGTYTVQIHDGK-AKSQSSLVLIGDAFK 1111 E + + GK A S V++ FK Sbjct: 24471 TGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 24503 Score = 216 bits (551), Expect = 1e-55 Identities = 213/874 (24%), Positives = 350/874 (40%), Gaps = 152/874 (17%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 T+ S++L +V G P PV+ W K G + A I++ L +++ + D Sbjct: 29457 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-----IDTTESYSLLIVDKVNRYD 29511 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGD-------EEPFRSVGLPIGLP-LSSMIPYTH 275 Y+ A N G+ S V V G E SV + +P + P + Sbjct: 29512 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 29571 Query: 276 FDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE 335 + V+ E F+ TVT KC+ + V+ ++R +L E+ +G Sbjct: 29572 YIVEKREAAMRAFK----TVTTKCSKTLYRISGLVEGTMYYFR---VLPEN-----IYGI 29619 Query: 336 GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDAN 395 G+ + + LV+ P P L+ D Sbjct: 29620 GEPCETSDAV--------------------------------LVSEVPLVPAKLEVVDVT 29647 Query: 396 RDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIF 455 + V + W+ P S + GY ++ C+ GT W++ + ++ VT L EG Y+F Sbjct: 29648 KSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLF 29707 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP-GPP 514 R+RA N G+S P + V A+ DLR L + L + I+ VP G P Sbjct: 29708 RIRAQNEKGVSEPR---ETVTAVTVQDLRVLPTIDLSTMPQKTIH---------VPAGRP 29755 Query: 515 TGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 + R SW +F + S +RV +T + + + + Sbjct: 29756 VELVIPIAGRPPPAASW------------FFAGSKLRES---ERVTVETHTKVAKLTIRE 29800 Query: 575 LMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 + + + N G L +P T PI+ ++ Sbjct: 29801 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA-------------- 29846 Query: 625 KTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIF 682 TS+ + W+ P+ + L GY V+ A W P + + + F LT G +Y+F Sbjct: 29847 -TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVF 29904 Query: 683 RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 RV A N G+ Q S+VI+ ++++ +P P + + + MTL W P+ GGS + Sbjct: 29905 RVAATNRFGIGSYLQ-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 29963 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 GY ++++EV W VN P T GLTEG YE ++ A+N G G+PS PS+ Sbjct: 29964 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30023 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P PG + + TS+ + W P G S V+GY ++ ++ D EW Sbjct: 30024 IVAMDPIAP-PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKC 30082 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 N T T R ++ L QG Y FRV A NA G G+P++ PGT +++ ++ Sbjct: 30083 NTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLE- 30132 Query: 923 QGNIYLGFDCQEMTDASQFT---------------------WCKSYEEISDDERFKIETV 961 Y ++ E F W K ++IS +R I T Sbjct: 30133 ----YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATS 30186 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 H++L +K D+ D GTY + + + G + ++ Sbjct: 30187 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 30220 Score = 216 bits (549), Expect = 2e-55 Identities = 172/613 (28%), Positives = 259/613 (42%), Gaps = 54/613 (8%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 ++ P +P A W D +L+ KM A L S + D+G+YTL++ +R Sbjct: 13414 ILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR- 13472 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 V S + D V P AP +L+ D +D V +TW+PP+ SP+ GY V++ Sbjct: 13473 -VKTISG-----EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEK 13526 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 EV W + D V ++ V L +G+ Y+F+V A N G P+ V + V P Sbjct: 13527 REVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTP- 13584 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 A VP PP V + + N + L+W+PP G Sbjct: 13585 --------------------------ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSR 13618 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ GS W V V + V L EGK Y +RV + NR G S+PS T Sbjct: 13619 IKGYIVERCPRGSDKW--VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 13676 Query: 601 SPIQAQDVTVVPS--APGRVLASRNTKTSVVVQWDRP---KHEEDLLGYYVDCCVAGTNL 655 IQA D P ++LA K ++ K E + D + Sbjct: 13677 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 13736 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY 715 N V + YI ++AVN G + E +V L P P Sbjct: 13737 ITIENVPKKSTVTIVDSKRSDTGTYI--IEAVNVCGRATAVVEVNV------LDKPGPPA 13788 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL 775 + + S L W P+ GGS I Y +++R + WH++ SS K T L Sbjct: 13789 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL-SSTVKDTNFKATKL 13847 Query: 776 TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKA 835 Y F++AA N+ G+GEP S + PGP L ++ ++ + W Sbjct: 13848 IPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTLTWCE 13905 Query: 836 PVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 P G SP++GY+V+ + D +W+ N+ + +V L K Y FRV A N G Sbjct: 13906 PDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGP 13965 Query: 896 GKPSDTSEPVLVE 908 GKPS ++EP+L++ Sbjct: 13966 GKPSKSTEPILIK 13978 Score = 207 bits (526), Expect = 8e-53 Identities = 199/842 (23%), Positives = 329/842 (39%), Gaps = 127/842 (15%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 ++G P P V W KDG + + A + I+S TL + D Y +N G Sbjct: 24731 IRGKPIPDVVWSKDGKELEETA--ARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 24788 Query: 237 QVSTNAAVVVRRFRGDEE-PFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETV 295 S V V G E P + G+ Sbjct: 24789 TKSIPITVKVLDRPGPPEGPLKVTGV---------------------------------T 24815 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKES----KWTKMFFGEGQASLSFSHLHKDDEG 351 KC + P L+ Y ++ K WT++ + + L +E Sbjct: 24816 AEKCYLAWNPPLQDGGANISHY---IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEY 24872 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 ++ + V++ G+ + V +P PG P + +D ++VTW P Sbjct: 24873 IFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITKDSMVVTWARPVDDGG 24930 Query: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRV 471 + + GY +++ + W +CN + + VTGL EG SY FRV A N+AG+ PS Sbjct: 24931 TEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEP 24990 Query: 472 SDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW 531 S A D A+Y PGPP+ ++ SR+ V L+W Sbjct: 24991 SVFYRACD------------------ALYP---------PGPPSNPKVTDTSRSSVSLAW 25023 Query: 532 EPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANR 590 P G P+ Y +E + W T ++ ++ V L E Y FR+ + N Sbjct: 25024 SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINS 25083 Query: 591 HGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTKTSVVVQWDR 634 G+ EP+ + + AQ+ V + SA R+ + + V+W++ Sbjct: 25084 EGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK 25143 Query: 635 PKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 E +L V + + V+ +T + + + N Sbjct: 25144 A---EGILTDRAQIEVTSS------------FTMLVIDNVTRFDSGRYNLTLEN------ 25182 Query: 695 NSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 NS L PS P +T+ S+TL W+ P GG+ I Y ++KRE Sbjct: 25183 NSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 25242 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 K + + ++ +K T ++ L EG Y F++ A N GIG P++ +E K +P PG Sbjct: 25243 KAYATITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLP-PG 25300 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 +T +V + + W+ P G S ++GY V+ + + + +W T Q T + Sbjct: 25301 ---RVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE--ATI 25355 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL---VEARPGTK----EISAGVDEQGNIY 927 S L G+ YVFRV AVN G P PV+ +E +P + + EQ I Sbjct: 25356 SGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKID 25415 Query: 928 LGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 + F + + W K + + + R + + + L +K KED+GTY + VS++ Sbjct: 25416 VPFKGRPQATVN---WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 25472 Query: 988 DG 989 G Sbjct: 25473 AG 25474 Score = 206 bits (525), Expect = 1e-52 Identities = 201/762 (26%), Positives = 307/762 (40%), Gaps = 95/762 (12%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + ++++ +K+ V G P P + W KDG + Q + +E Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT---RVNVEETATSTV 24368 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I + DD Y+ ATN+ G + N +V+V E+P G P+G + + Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVL-----EKP----GPPVG-----PVRF 24414 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 F V E T C + KR W+ + Sbjct: 24415 DEVSADF-----VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATV---------- 24459 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCH 392 + ++ + L E + + +R G S V P G PG P Sbjct: 24460 --ARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VT 24514 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 ++D ++V W P + ++GY +++ E + WV+ N P++ K+ TGL EG Sbjct: 24515 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 24574 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y F+V A N GI +PS+VS+ A DP D Sbjct: 24575 YEFKVSAENIVGIGKPSKVSECFVARDPCD------------------------------ 24604 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYA 571 PP A I+RN V L W+ P G + Y +EK + G W + + T V + Sbjct: 24605 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TNVLETEFT 24663 Query: 572 VFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L+E + Y FRV++ N G SEPS+ + I A+D AP L + VV Sbjct: 24664 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEI---DAPNASLDPKYKDVIVVH 24720 Query: 631 QWDRPKHEEDLLGYYVDCCV---AGTNLWEPCNH----KPIGYNRFVVHGL--TTGEQYI 681 + E D+ G + V G L E I VV T G QYI Sbjct: 24721 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGS 740 ++ V +S I V+ L P P G + + L W P GG+ Sbjct: 24781 LKLSNVGGT-------KSIPITVK-VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 24832 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I Y ++KRE +W +V S+ + V L G+ Y F++ AVN GIGEP + Sbjct: 24833 NISHYIIEKRETSRLSWTQV-STEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESG 24891 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 C + PGP + S+V+ W PV G + + GY ++ R+++ W Sbjct: 24892 PVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 N+ T + L+V+ L +G +Y FRV A NA GVG+PS+ S Sbjct: 24950 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 24991 Score = 206 bits (525), Expect = 1e-52 Identities = 205/865 (23%), Positives = 323/865 (37%), Gaps = 151/865 (17%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 S+++ VQG P P V W+KDG + + I G +L + A D Y+ Sbjct: 27975 SLRIKALVQGRPVPRVTWFKDG---VEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTV 28031 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEE-PFRSVGLP-------IGLPLSS-MIPYTHFDVQF 280 A NA G V V+ G P R + PL+ P TH+ ++ Sbjct: 28032 EAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEK 28091 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 E T R + KC +K + +R + K FG G+ Sbjct: 28092 RE----TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNK--------FGVGRPL- 28138 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANR 396 D+DP+V P AP + + Sbjct: 28139 ---------------------------------DSDPVVAQIQYTVPDAPGIPEPSNITG 28165 Query: 397 DYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQC-NDAPVKICKYPVTGLFEGRSYIF 455 + + +TW P + S + Y ++R E + WV+ + P+ ++ VTGL EG Y F Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 28225 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPT 515 V A N+AG+ S +S + +P++ PGPPT Sbjct: 28226 HVMAENAAGVGPASGISRLIKCREPVN---------------------------PPGPPT 28258 Query: 516 GVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 V ++ S+ V L W P G + + Y IE G W +VNA+ V++ RY V D Sbjct: 28259 VVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT-RYTVTD 28317 Query: 575 LMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS----------------APGRV 618 L G+ Y FRV + N G + E+T I+A D P A R+ Sbjct: 28318 LQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRL 28377 Query: 619 LASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 + + + W +P L T E CN G V + + Sbjct: 28378 FIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSK 28437 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 F VK L P P IT + S TL W P G Sbjct: 28438 SITFTVKV---------------------LDTPGPPGPITFKDVTRGSATLMWDAPLLDG 28476 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+ I Y ++KRE ++W ++ ++ I V+ L EG Y F+++AVN G+GEP + Sbjct: 28477 GARIHHYVVEKREASRRSWQVISEKCTRQ-IFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 28535 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E +P P L + +S V+ W P + G S ++GY ++ R++ + Sbjct: 28536 MPEPIVATE----QPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 28591 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W+ T V L + Y FRV+A N G +P + V+++ +I Sbjct: 28592 WVEAGHTKQLT--FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE----PQIEP 28645 Query: 919 GVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDHSKL 967 D G C+ + A + TW + + +R I T D + L Sbjct: 28646 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTL 28705 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSS 992 +K+ + D G Y +++ +T GV + Sbjct: 28706 TVKDSMRGDSGRYFLTLENTAGVKT 28730 Score = 206 bits (523), Expect = 2e-52 Identities = 163/604 (26%), Positives = 252/604 (41%), Gaps = 58/604 (9%) Query: 311 QPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 +P+ W++D+ + E T + +L + D G Y +V F Sbjct: 16847 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC--VVVENSTGSRKGFC 16904 Query: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 V D G P P+ + +DY++++WKPP S + Y +++ EVG + W+ Sbjct: 16905 QVNVVDR--PGPPVGPVSFD--EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 16960 Query: 431 QCNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAV 489 A K CK V+ L EG+ YIFR+ A N GIS P VSD++ A D Sbjct: 16961 PVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL-VSDSMKAKDRF-------- 17009 Query: 490 HLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKS 549 +VP P +E++++ +++W P GK Y +EK Sbjct: 17010 -------------------RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR 17050 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W RV ++ V DL+EG Y FRV + N G+ +PS + P+ A+D Sbjct: 17051 ETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI 17110 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 PS P A T SV + W P+H+ +LGY V+ G W NH P Sbjct: 17111 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 17170 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 ++ V GL G+ Y FRV AVNA G S+ + + + V+ L P + Sbjct: 17171 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 17230 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 + ++ G P K + PT +D GS E + Sbjct: 17231 KVGDTLRLSAIIKGVPFPKVTWKKED------------RDAPTKARIDVTPVGSKLEIRN 17278 Query: 786 AAVNLAGI----GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 AA GI E S+ + + +PGP DL E+R S + WK P+ G Sbjct: 17279 AAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGG 17338 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y V+ R+ + +W ++ T+ + L +G Y+FRV A N G G +T Sbjct: 17339 SVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGPFVET 17397 Query: 902 SEPV 905 +P+ Sbjct: 17398 PKPI 17401 Score = 204 bits (520), Expect = 4e-52 Identities = 208/851 (24%), Positives = 344/851 (40%), Gaps = 108/851 (12%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLE------INRADFDDT 224 +++ ++G PTP W DG +A + G + I + + T E I T Sbjct: 15828 IRIPAVIKGRPTPKSSWEFDGKAK-KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 15886 Query: 225 ATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF 284 YS A N GQ + N V V G + + + G Sbjct: 15887 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRG-------------------- 15926 Query: 285 GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSH 344 + L M PD + + + WTK+ G + Sbjct: 15927 ---------SCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPD 15974 Query: 345 LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTW 403 L + + + +R +R G+ + A DP+ P P+ L+ ++ V ++W Sbjct: 15975 LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYP--PDPPIKLKIGLITKNTVHLSW 16032 Query: 404 KPPNTTTESPVMGYFVDRCE---VGTNN--WVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 KPP SPV Y V+ GT W QCN V+ ++ V L EG Y FRV+ Sbjct: 16033 KPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVK 16092 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD--AQVPGPPTG 516 AVN+AG+S+PS A + P D +R KE ++ + A++ G P Sbjct: 16093 AVNAAGVSKPS------ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVP-- 16144 Query: 517 VHASEISRNYVVLSW---EPPTPRGKDPLMY--FIEKSVVGSGSWQRVNAQTAVRSPRYA 571 + L+W P P K+P++Y + K VV + + Y Sbjct: 16145 ---------FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT 16195 Query: 572 VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 + + + + N L P PI+ + V+ + + Sbjct: 16196 I-TAVNNLGTASKEMRLNV--LGRPGPPVGPIKFESVSA---------------DQMTLS 16237 Query: 632 WDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 W PK + + Y ++ A W + +P + + L G +Y+FR+ A N Sbjct: 16238 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNK 16296 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 G+ E +S+ + +VP P T+ + +SMT+ W+ P++ GGSP+ GY+L+ Sbjct: 16297 YGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM 16355 Query: 750 REVHHKNWHEVNSSPSKPTIL----TVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++ K W VN P K L V GL EGS Y+F++ A+N AG+G S PS+ Sbjct: 16356 KDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 16415 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P PGP + + +S + W P+ G S V+GY V+++EE EW Sbjct: 16416 RDPIAP-PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 16473 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--PGTKEISAGVDEQ 923 L V+ L++G Y FRVRAVN G+G+P + ++ + ++ R ++ A V ++ Sbjct: 16474 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDR 16533 Query: 924 GNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLG 978 ++ G + + S TW + E + + IET S + +KN + G Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQG 16591 Query: 979 TYSVSVSDTDG 989 YS+ + G Sbjct: 16592 VYSLLAKNEAG 16602 Score = 203 bits (516), Expect = 1e-51 Identities = 211/854 (24%), Positives = 339/854 (39%), Gaps = 152/854 (17%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFD-----------DTA 225 V G P P ++W KDG + G LEI ADF D+ Sbjct: 21485 VSGRPPPTMEWSKDGKEL--------------EGTAKLEIKIADFSTNLVNKDSTRRDSG 21530 Query: 226 TYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFG 285 Y+ ATN G V V G E PL+ Sbjct: 21531 AYTLTATNPGGFAKHIFNVKVLDRPGPPEG----------PLA----------------- 21563 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK---WTKMFFGEGQASLSF 342 VT E + KC + P L + + Y V +E+ WT + L Sbjct: 21564 VT-----EVTSEKCVLSWFPPLDDGGAKIDHYI--VQKRETSRLAWTNVASEVQVTKLKV 21616 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + L K +E ++ + V++ GV + V +P G P P + + +D ++V Sbjct: 21617 TKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY--GPPDPPKNPEVTTITKDSMVVC 21674 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P++ S ++ Y V+R + W++CN + +Y V+GL EG Y FR+ A N+ Sbjct: 21675 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 21734 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AGIS PS S A D +++ PGPP + Sbjct: 21735 AGISAPSPTSPFYKACD------------------TVFK---------PGPPGNPRVLDT 21767 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 SR+ + ++W P G + Y +E ++ WQ V +++ Y + L E + Y Sbjct: 21768 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 21827 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTK 625 R+ + N GL EP+ + +A+D VT+ R+ + Sbjct: 21828 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 21887 Query: 626 TSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685 + V+W R H E L ++ + T L NRF +YI V+ Sbjct: 21888 PAPEVKWARD-HGESLDKASIESTSSYTLLIVG------NVNRF------DSGKYILTVE 21934 Query: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 + + +S + V+ L P P + + S+TL W P GGS I Y Sbjct: 21935 -------NSSGSKSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNY 21986 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++KRE K + V ++ K T VD L EG Y F++ A N GIG P++ +E K Sbjct: 21987 IVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 22045 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 +P PG +T +V S+ + W+ P + G S + GY V+ + + + +W T Sbjct: 22046 SERPLP-PGK---ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--A 22099 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---------GTKEI 916 T ++ L QG+ Y FRV A N G+ P S PV+ + T + Sbjct: 22100 TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV 22159 Query: 917 SAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKE 975 AG D + ++ ++G TW K + R E+ ++S L +K+ +E Sbjct: 22160 LAGEDLKVDVPFIG------RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 22213 Query: 976 DLGTYSVSVSDTDG 989 D+G Y V ++++ G Sbjct: 22214 DVGHYVVKLTNSAG 22227 Score = 200 bits (508), Expect = 1e-50 Identities = 212/862 (24%), Positives = 330/862 (38%), Gaps = 118/862 (13%) Query: 165 VWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH----TLEINRAD 220 V E +V + ++G P P + W+K EP Y N V TL I ++ Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 16187 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQF 280 DT Y+ A N G S + V G P+G P+ F+ Sbjct: 16188 RSDTGLYTITAVNNLGTASKEMRLNV---------LGRPGPPVG-PIK-------FESVS 16230 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 ++ +++ + K T V KR R W KE +T EG Sbjct: 16231 ADQMTLSWFPPKDDGGSKITNYVIE--KREANRKTWVHVSSEPKECTYTIPKLLEGHE-- 16286 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 Y RI+++ + + PGAP R+ + Sbjct: 16287 ------------YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMT 16334 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC----KYPVTGLFEGRSYIFR 456 V W+ P SPV GY+++ + + W + N P+K Y VTGL EG Y FR Sbjct: 16335 VNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 16394 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 V A+N+AG+ S SD A DP+ PGPP Sbjct: 16395 VYAINAAGVGPASLPSDPATARDPI---------------------------APPGPPFP 16427 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDL 575 ++ +++ L W PP G + Y +E G W++ VR + V L Sbjct: 16428 -KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GKDKEVRGTKLVVTGL 16485 Query: 576 MEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--------------APG--RVL 619 EG Y FRV + N G+ EP E+T I+ +D V P A G R++ Sbjct: 16486 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 16545 Query: 620 ASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 A + K V W+ + ++ + + + C Q Sbjct: 16546 AYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS---------------HQ 16590 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 ++ + A N G + + DV+ V + P + +T +C L W P+ GG Sbjct: 16591 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCK-----LTWFSPEDDGG 16645 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPI Y ++KRE + W V + ++ TV GL +G Y F+IAA N G+G + Sbjct: 16646 SPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSIGMGPFVET 16704 Query: 800 SEHFKC-EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 SE E T+PE DL EV ++ + W P Y G S + Y ++ R + Sbjct: 16705 SEALVIREPITVPERPE--DLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 16762 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 + V +R V L++G TY +RV AVN G GKPS ++P+ + + Sbjct: 16763 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 16822 Query: 919 GVDEQGNIYLGFDCQEMTDA------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 ++ I +G + +T + +W K ++ +D+R I+T L Sbjct: 16823 DFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 16881 Query: 973 DKEDLGTYSVSVSDTDGVSSSF 994 + D G Y V V ++ G F Sbjct: 16882 KRSDSGKYCVVVENSTGSRKGF 16903 Score = 199 bits (506), Expect = 2e-50 Identities = 202/839 (24%), Positives = 329/839 (39%), Gaps = 101/839 (12%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +V+ ++G P P +W DGS I Y +E++ L I DT Y Sbjct: 17527 TVRFPAIIRGVPVPTAKWTTDGSEI---KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 +NA G + + V G P G P DV Sbjct: 17584 TVSNAAGSKTVAVHLTVLDVPGP---------PTG-------PINILDVT---------- 17617 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 E T++ + P P + + ++ W + G + L HL K Sbjct: 17618 PEHMTISWQ-----PPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 17672 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAPGAPMDLQCHDANRDYVIVTWKP 405 E ++ +R ++ GV D+ P V P P D + V+W Sbjct: 17673 EYVFRVRAENKIGVGPPL------DSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTL 17726 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + SP+ GY+++R EV T WV+ N P+ K+ VTGL+EG +Y FRV A N AG+ Sbjct: 17727 PKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGL 17785 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 S+PS SD + A P+ + PGPP + SR Sbjct: 17786 SKPSPSSDPIKACRPI---------------------------KPPGPPINPKLKDKSRE 17818 Query: 526 YVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 L W P G P++ Y +E G+ W R+N +R + V L+EG Y FR Sbjct: 17819 TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFR 17878 Query: 585 VLSANRHGLSEPSEITSPIQAQDVTVVPSAP-----GRVLASRNTKTSVVVQWDRPKHEE 639 + +AN G EP E+ + A+D+ P V+ R +T ++ + + E Sbjct: 17879 IKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEP 17938 Query: 640 DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQES 699 D+ + + P + +YI ++A S ++Q S Sbjct: 17939 DITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI-----ISAKNSSGHAQGS 17993 Query: 700 DVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHE 759 ++ V L P + + N + T+ W+ P +GGS I + ++ R+ + K W Sbjct: 17994 AIVNV---LDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSI 18050 Query: 760 VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDL 819 V S +K I L + Y F++ A N G+G P+ ++ + PG +L Sbjct: 18051 VASDVTKRLIKA--NLLANNEYYFRVCAENKVGVG-PTIETKTPILAINPIDRPGEPENL 18107 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + T + + W+ P Y G SP Y V+ R + + +W V++ + + V + Sbjct: 18108 HIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVE 18167 Query: 880 GKTYVFRVRAVNANG---------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 + Y FRV+ N G V D +PVL G + AG + + G Sbjct: 18168 NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG--DTIRLEAGV 18225 Query: 931 DCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + + + +T K +++ R KI+T D SK L + D G Y V+ ++T G Sbjct: 18226 RGKPFPEVA-WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283 Score = 198 bits (503), Expect = 4e-50 Identities = 178/670 (26%), Positives = 280/670 (41%), Gaps = 68/670 (10%) Query: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313 EP S G PI + P DV+F + V + GE + + + P P Sbjct: 25770 EPSESTG-PIIVKDDVEPPRVMMDVKFRDVIVV---KAGEVLKINADIAGRP-----LPV 25820 Query: 314 AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W +D + ++E T++ + L+ + D G Y L + + G + V Sbjct: 25821 ISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 25880 Query: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433 D G P P+++ A + ++W P + + Y V++ E W C Sbjct: 25881 DK----PGPPAGPLEINGLTAEK--CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC- 25933 Query: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493 + +++ VT L +G YIFRV VN G+ P S A+ ALDP Sbjct: 25934 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKALDPF------------ 25980 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVG 552 VP PPT + + +++ + L W P G + Y IE+ Sbjct: 25981 ---------------TVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 26025 Query: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612 S W RVN + V R L EG Y +RV + N GLS PSE + I+A+D +P Sbjct: 26026 SLRWVRVN-KKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 26084 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 S P + + KT++ + W +P + + GY V+ + W+ G + Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 26143 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVP----SHPYGITLLNCDGHS 726 + GLTTG +Y+FRVK+VN VG S+ S SD + P TL+ G S Sbjct: 26144 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 26203 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 T+ VP G P+ K + + V+++ S+ T LT++ ++ + Sbjct: 26204 FTM--TVP--FRGRPVPNVLWSKPDTDLRTRAYVDTTDSR-TSLTIENANRNDSGKYTLT 26258 Query: 787 AVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSG 846 N+ + + PGP ++T +V S V+ W P G +PV Sbjct: 26259 IQNVLS-------AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKN 26311 Query: 847 YFVDFREEDAGEWITVNQTTTANRY-LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE W++V T NR KV++LQ+G Y FRV N GVG P++T E V Sbjct: 26312 YHIEKREASKKAWVSV--TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 26369 Query: 906 LVEARPGTKE 915 + +P E Sbjct: 26370 KITEKPSPPE 26379 Score = 196 bits (497), Expect = 2e-49 Identities = 206/843 (24%), Positives = 341/843 (40%), Gaps = 125/843 (14%) Query: 170 SVKLCFTVQGFPTPVVQWYKD------GSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 SVKL + G P P ++WYKD +L+C +E+ + ++ I AD + Sbjct: 26889 SVKLRAGISGKPAPTIEWYKDDKELQTNALVC---------VENTTDLASILIKDADRLN 26939 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y NA G S V + G P G P+ F EK Sbjct: 26940 SGCYELKLRNAMGSASATIRVQILDKPG----------PPGGPIE-------FKTVTAEK 26982 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 + +R + K T + KR R W L+E ++ + Sbjct: 26983 ITLLWRPPADDGGAKITHYIVE--KRETSRVVWSMVSEHLEE------------CIITTT 27028 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-GAPGAPMDLQCHDANRDYVIVT 402 + K +E ++ +R V++ G+ + V + VT G PG P + ++ + V Sbjct: 27029 KIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKITKNSMTVV 27085 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P S + GYF+++ + + W + ++ + VTGL E Y +RV AVN+ Sbjct: 27086 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 27145 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AG S S+ A DP+D PGPP + ++ Sbjct: 27146 AGQGPFSEPSEFYKAADPID---------------------------PPGPPAKIRIADS 27178 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 +++ + L W P G + Y +E W V+ + VR+ Y V +L G +Y Sbjct: 27179 TKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNY 27238 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP------GRVLASRNTKTSVVVQWD-R 634 FRV + N G EP E+ P+QA+D+ P V+A V++ + R Sbjct: 27239 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGR 27298 Query: 635 P------KHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 P + +E LG + T+ + N TG+ YI ++ N Sbjct: 27299 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN-------DTGK-YILTIE--N 27348 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 VG ++S S +KV L P+ + + + ++TL W P GGSPI+ Y ++ Sbjct: 27349 GVGEPKSSTVS--VKV---LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE 27403 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+ + W V+ S + +D L+E + + F++ A N GIGEP + +E K Sbjct: 27404 KRDATKRTWSVVSHKCSSTSFKLID-LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE- 27461 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 P P DL+ + TS+++ W P + G S ++ Y V+ + + W + T Sbjct: 27462 ---VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 27518 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG---- 924 ++VS L++ FRV A N G+ P T P+ V+ T E+ D G Sbjct: 27519 E--IEVSQLKEQSVLEFRVFAKNEKGLSDPV-TIGPITVKELIITPEVDLS-DIPGAQVT 27574 Query: 925 -----NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGT 979 N++L + S +W K + + E + + L +KN KE G Sbjct: 27575 VRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGK 27633 Query: 980 YSV 982 Y+V Sbjct: 27634 YTV 27636 Score = 194 bits (493), Expect = 5e-49 Identities = 199/802 (24%), Positives = 323/802 (40%), Gaps = 126/802 (15%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P R P +W + D ++++ + SL ++++ D G YTL + + Sbjct: 22962 LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSS 23019 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G SAF+ VR D P P++L+ + +D V +TW+PP S + Y V++ Sbjct: 23020 GTK--SAFVTVRVLD-----TPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 23072 Query: 422 CEVGTNNWVQCNDAPVKIC---KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478 E ++ A V C + + L EG SY FRV A N GI P++ +D + Sbjct: 23073 REATRKSYA----AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV- 23127 Query: 479 DPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRG 538 A+VP PP + +++RN V LSW P G Sbjct: 23128 -----------------------------AEVPQPPGKITVDDVTRNSVSLSWTKPEHDG 23158 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 ++ Y +E S W V+S + + +L +G+ Y+FRV++ N G S+P Sbjct: 23159 GSKIIQYIVEMQAKHSEKWSEC---ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 23215 Query: 598 EITSPIQAQDVTVVPS-----APGRVLASRNTKTSVVVQWDRPKHE----------EDLL 642 + PI A+D+ + P + V ++ K V + RPK + Sbjct: 23216 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPIS-GRPKPTITWTKDGLPLKQTT 23274 Query: 643 GYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVI 702 V + T L HK G QY + N VG S E Sbjct: 23275 RINVTDSLDLTTLSIKETHK------------DDGGQY--GITVANVVGQKTASIEI--- 23317 Query: 703 KVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 L P P G + + S+TL W P ++GG I Y + KR+ W V+ Sbjct: 23318 ---VTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 23374 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAG--IGEPSDPSEHFKCEAWTMPEPGPAYDL 819 ++ ++ T L V L G+ Y+F+I A N G SDP + EPGP Sbjct: 23375 ATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI----VAQYPYKEPGPPGTP 23429 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + S+V+ W PV +G SPV GY ++ +E ++ W VN+T + K +L++ Sbjct: 23430 FATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEE 23489 Query: 880 GKTYVFRVRAVNANGVGK---------------PSDTSEPVLVEARPGTKEISAGVDEQG 924 G Y FRV A N GVGK P T EP++V+ T + + V + G Sbjct: 23490 GIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGG 23549 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 ++ G+ E D W K+ + +F + + + + + K G S Sbjct: 23550 SMITGY-IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 23608 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAE-HLSP 1043 T +++ +E++ P I + + I F L+A+ H P Sbjct: 23609 DSTGPITA---------------KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKP 23653 Query: 1044 DASYRFIINDREVSDSEIHRIK 1065 + ++ D+E+ +S IK Sbjct: 23654 LPTIEWLRGDKEIEESARCEIK 23675 Score = 193 bits (490), Expect = 1e-48 Identities = 206/864 (23%), Positives = 336/864 (38%), Gaps = 147/864 (17%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 +K+ + G P PV+ W KDG + E + I S L + DT Y Sbjct: 25807 LKINADIAGRPLPVISWAKDG---IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 25863 Query: 231 ATNAHG--QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF 288 N G V+ N V+ ++P G P G LE G+T Sbjct: 25864 LKNVAGTRSVAVNCKVL-------DKP----GPPAGP---------------LEINGLTA 25897 Query: 289 RREGETVTLKCTMLVTPDLKRVQPRAEWYRD-DVLLKESK------WTKMFFGEGQ-ASL 340 KC+ L +P+ + D D + E + WT + GE Q S Sbjct: 25898 E--------KCS------LSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSC 25942 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 + L K +E ++ + V++ GV + + ++ DP +P P L+ ++ + Sbjct: 25943 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEITSVTKESMT 26000 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + W P + S + GY ++R E + WV+ N PV + TGL EG Y +RV A Sbjct: 26001 LCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAE 26060 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 N+AG+S PS S + A DP+ L P PP+ Sbjct: 26061 NAAGLSLPSETSPLIRAEDPVFL---------------------------PSPPSKPKIV 26093 Query: 521 EISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGK 579 + + + ++W P G P+ Y +E W+ + ++R Y + L G Sbjct: 26094 DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK--TSIQSLRGTEYTISGLTTGA 26151 Query: 580 SYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV---------- 629 YVFRV S N+ G S+PS+ + P A++ P + S KT +V Sbjct: 26152 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD---IDSEMRKTLIVKAGASFTMTV 26208 Query: 630 ---------VQWDRPKHEEDL-LGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGE 678 V W +P + DL YVD + T+L E N G + + + Sbjct: 26209 PFRGRPVPNVLWSKP--DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 26266 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 VK L P P IT+ + S L W VP+ G Sbjct: 26267 SLTLVVK---------------------VLDTPGPPTNITVQDVTKESAVLSWDVPENDG 26305 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+P+ Y+++KRE K W V ++ ++ + V L EG++Y F+++ N G+G P++ Sbjct: 26306 GAPVKNYHIEKREASKKAWVSVTNNCNRLS-YKVTNLQEGAIYYFRVSGENEFGVGIPAE 26364 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E K +P P L + S+ + W P + G S + Y V+ E+ Sbjct: 26365 TKEGVK----ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKN 26420 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W V + + VS L++ Y FRV A N G+ P + PVL++ + EI Sbjct: 26421 W--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDM 26478 Query: 919 GVDEQGNIYLGFDCQEMTD-------ASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 +Y+ D + T + + RF E ++ + LK Sbjct: 26479 KNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKE 26538 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFV 995 D G Y ++ +++ G + +F+ Sbjct: 26539 SVTADAGRYEITAANSSGTTKAFI 26562 Score = 192 bits (489), Expect = 2e-48 Identities = 159/642 (24%), Positives = 274/642 (42%), Gaps = 79/642 (12%) Query: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438 +T P P L ++D V +TW P S ++ Y V+ E G NWV+C A K Sbjct: 26371 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAK 26428 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIA 498 + V+GL E Y FRV A N AG+S P + V + L+ + + Sbjct: 26429 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 26488 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVL--SWEPPTPRGKDPLMYFIEKSVVGSGSW 556 +L+ D + G P + +SR+ V L + T + L +++SV Sbjct: 26489 RAGSNLKVDIPISGKP--LPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGR 26546 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG 616 + A + + K+++ V+ L P T P+ D+T Sbjct: 26547 YEITAANSSGTT----------KAFINIVV------LDRPGPPTGPVVISDIT------- 26583 Query: 617 RVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGL 674 + SV ++W+ PK++ + Y + T +W + + V L Sbjct: 26584 --------EESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS-ATVARTMMKVMKL 26634 Query: 675 TTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVP 734 TTGE+Y FR+KA N G+S++ +S + V+ T P P + N S+T+GW P Sbjct: 26635 TTGEEYQFRIKAENRFGISDHI-DSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 26693 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 +GGS ++GY+L+ ++ + W + N + T V ++ G +YEF++ A N AG+G Sbjct: 26694 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 26753 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PS PSE + P ++ ++ S+ + W+ P + G S ++GY V+ R+ Sbjct: 26754 KPSHPSE----PVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL 26809 Query: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPV-------- 905 G W + T +S L Q Y FRV A NA G + PS+ P+ Sbjct: 26810 PDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGG 26869 Query: 906 -----------LVEARPGTK-EISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDD 953 +V+ R GT ++ AG+ + A W K +E+ + Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGK-------------PAPTIEWYKDDKELQTN 26916 Query: 954 ERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 +E D + + +K+ D+ + G Y + + + G +S+ + Sbjct: 26917 ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 26958 Score = 191 bits (485), Expect = 4e-48 Identities = 214/857 (24%), Positives = 337/857 (39%), Gaps = 113/857 (13%) Query: 177 VQGFPTPVVQWYKDGSLI---CQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATN 233 V G P P ++W K+ ++I A + K + + L I +A +D TY+ A+N Sbjct: 15422 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASN 15481 Query: 234 AHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGE 293 G V N V E + P L ++ D++ E +T+ + Sbjct: 15482 RLGSVFRNVHV---------EVYDRPSPPRNLAVT--------DIK-AESCYLTWDAPLD 15523 Query: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLY 353 + T V + +AEW E ++ L + + + Sbjct: 15524 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRY------------GIWKLIPNGQYEF 15571 Query: 354 TLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 +R V++ G+SD V DP + G PG P L + ++V+W PP S Sbjct: 15572 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---RTKGSMLVSWTPPLDNGGS 15628 Query: 413 PVMGYFVDRCEVGTNNWVQCNDAPV-----KICKYPVTGLFEGRSYIFRVRAVNSAGISR 467 P+ GY++++ E G+ W + + AP+ K ++ V L EG Y FR A+N+AGI Sbjct: 15629 PITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGP 15688 Query: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527 PS SD A DP+ PGPP+ + +++ + Sbjct: 15689 PSEPSDPEVAGDPIF---------------------------PPGPPSCPEVKDKTKSSI 15721 Query: 528 VLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA-QTAVRSPRYAVFDLMEGKSYVFRV 585 L W+PP G P+ Y +E G+ W+RVN + + V +L E + Y FRV Sbjct: 15722 SLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRV 15781 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA---------SRNTKTSVVVQWDRPK 636 + N G SEPS+ T I A D+ P + A S+ +V+ PK Sbjct: 15782 KAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPK 15841 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV-----HGLTTGEQYIFRVKAVNAVG 691 + G G + N V+ TG+ + + A N G Sbjct: 15842 SSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK---YSITAKNKAG 15898 Query: 692 MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751 Q++ +V+ + VP P + + + S L WK+P GG I GY ++KR Sbjct: 15899 -----QKTANCRVKV-MDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT 15952 Query: 752 VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811 + K W +VN T + D L+E Y F++ A N GIG P + + P Sbjct: 15953 IDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYP 16011 Query: 812 EPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED-----AGEWITVNQTT 866 P P L + ++ + WK P G SPV+ Y V+ D W N+ Sbjct: 16012 -PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070 Query: 867 TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEIS----AGVDE 922 V DL +G Y FRV+AVNA GV KPS T P + I V+E Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 16130 Query: 923 QGNIYLGFDCQEMTDASQFTWCK-------SYEEISDDERFKIETVGDHSKLYLKNPDKE 975 N+ + + + + TW K + E + D V D L + + Sbjct: 16131 GTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 16189 Query: 976 DLGTYSVSVSDTDGVSS 992 D G Y+++ + G +S Sbjct: 16190 DTGLYTITAVNNLGTAS 16206 Score = 188 bits (478), Expect = 3e-47 Identities = 179/740 (24%), Positives = 304/740 (41%), Gaps = 121/740 (16%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 VQW ++ ++ Q K+++ S +H L+I D Y +A + + A Sbjct: 12942 VQWLRNNMVVVQG---DKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAA 12998 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 + D++ + + +G PL+ ++PY + Sbjct: 12999 APKIKTADQD----LVVDVGKPLTMVVPYDAYP--------------------------- 13027 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG-QASLSFSHLHKDDEGLYTLRIVSRGGV 363 + AEW++++ L TK Q S K D+G Y + + ++ G Sbjct: 13028 ------KAEAEWFKENEPLS----TKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK 13077 Query: 364 SDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 ++ L V D PG +L+ + V + W+ P T S ++GY V+R + Sbjct: 13078 AEGFINLKVIDV-------PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 13130 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGR-SYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + WV D + C++ VTGL +G Y+FRV A N G P + V A D Sbjct: 13131 IKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYD 13189 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDP 541 VPGPP V ++++R V L+WEPP G + Sbjct: 13190 ---------------------------VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 13222 Query: 542 LMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITS 601 Y IE S W A V D++EG+ Y FRV + NR G+ +PS T Sbjct: 13223 TNYVIELRDKTSIRWDTAMTVRA-EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 13281 Query: 602 PIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPC 659 ++ D PS P + +S T++SV ++W+ P + +LGY ++ C G + W C Sbjct: 13282 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRC 13341 Query: 660 NHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ-----ESDVIKVQAALTVPSHP 714 N K + + V GL G +Y++RV A N G+S+ S+ +D V+ + + + Sbjct: 13342 NMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFK 13401 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNS-SPSKPTILTVD 773 G+ ++ + ++ VP P + + + + ++ + S +++ Sbjct: 13402 DGLEVIVPNPITIL----VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPS 13457 Query: 774 GLTEGSLYEFKI--------AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVR 825 ++ +Y K+ +++ I PS P E L F ++ Sbjct: 13458 ERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKE-----------------LKFGDIT 13500 Query: 826 DTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W+ P G SP++GY V+ RE W V T + V DL QGK Y+F Sbjct: 13501 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEF-TVPDLVQGKEYLF 13559 Query: 886 RVRAVNANGVGKPSDTSEPV 905 +V A N G G+P+ EPV Sbjct: 13560 KVCARNKCGPGEPAYVDEPV 13579 Score = 188 bits (477), Expect = 4e-47 Identities = 145/509 (28%), Positives = 233/509 (45%), Gaps = 82/509 (16%) Query: 371 FVRDADPLVTG----APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGT 426 FV ++ LV P P DL+ + ++ V +TW PP S ++ Y ++ +GT Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 16760 Query: 427 NNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG------ISRPSRVSDAVAA--- 477 + + + + KY V GL EG +Y +RV AVN G ++P D +A Sbjct: 16761 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 16820 Query: 478 ----LDPLDLRRLQAVHLEG-------------EKEIAIYQDDL---------------- 504 D L +R +A L G + E + +DD Sbjct: 16821 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 16880 Query: 505 --------------------EGDAQV-----PGPPTG-VHASEISRNYVVLSWEPPTPRG 538 +G QV PGPP G V E++++Y+V+SW+PP G Sbjct: 16881 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 16940 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 + Y IEK VG W V + +A + + V L+EGK Y+FR+ + N +G+S+P Sbjct: 16941 GSKITNYIIEKKEVGKDVWMPVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL 16998 Query: 598 EITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL 655 ++ ++A+D VP AP + + + TK S +V W++P H+ + + Y ++ + Sbjct: 16999 -VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKR 17056 Query: 656 WEPCNHKPIG-YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHP 714 W PI Y +F V L G QY FRV A N +G+ + S S + + + PS P Sbjct: 17057 WARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPP 17116 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTV 772 ++ +S+ L W+ P+ GGS ILGY ++ ++V + W N +P T V Sbjct: 17117 VNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKV 17176 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSE 801 GL +G Y+F++ AVN AG +P+ E Sbjct: 17177 TGLRDGQTYKFRVLAVNAAGESDPAHVPE 17205 Score = 187 bits (476), Expect = 5e-47 Identities = 190/783 (24%), Positives = 312/783 (39%), Gaps = 105/783 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + + V R +K+ +G P V W KDG + E + + S+ V + Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTL---KETTRVNVSSSKTVTS 25451 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I A +D TY +N+ G ++ ++V G P R + S P Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPP 25511 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + + + ++E + T W + Sbjct: 25512 EYDGGCQISNY-IVEKKETTSTT-------------------------------WHIVSQ 25539 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHD 393 + S+ L E + + +R G S +S V P PG P + Sbjct: 25540 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPF--SPPGPPGTPKVVH 25597 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 A + ++VTW+ P S V+GY ++ E + W + N + + V+GL EG Y Sbjct: 25598 ATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMY 25657 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 +RV A N AGI + S+ + V A DP D P Sbjct: 25658 EYRVYAENIAGIGKCSKSCEPVPARDPCD------------------------------P 25687 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + I+R V L W P G + Y +E+ + G W + N T ++ + V Sbjct: 25688 PGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCN-YTNIQETYFEV 25746 Query: 573 FDLMEGKSYVFRVLSAN-RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 +L E + Y FRV + N +SEPSE T PI +D P RV+ + +VV+ Sbjct: 25747 TELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKD----DVEPPRVMMDVKFRDVIVVK 25802 Query: 632 -WDRPKHEEDLLGY---YVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------Q 679 + K D+ G + G + E + I + H L T + Q Sbjct: 25803 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN---HTLLTVKDCIRRDTGQ 25859 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y+ +K N G + V+ P G+T C +L W P+ GG Sbjct: 25860 YVLTLK--NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKC-----SLSWGRPQEDGG 25912 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + I Y ++KRE H W + + T V L +G+ Y F++ VN G+GEP + Sbjct: 25913 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 25971 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 + +T+P P + ++T V S+ + W P G S +SGY ++ RE+++ W Sbjct: 25972 VAIKALDPFTVPSPPTSLEIT--SVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRW 26029 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS------EPVLVEARPGT 913 + VN+ + +K + L++G Y +RV A NA G+ PS+TS +PV + + P Sbjct: 26030 VRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSK 26089 Query: 914 KEI 916 +I Sbjct: 26090 PKI 26092 Score = 187 bits (475), Expect = 6e-47 Identities = 180/671 (26%), Positives = 294/671 (43%), Gaps = 73/671 (10%) Query: 349 DEGL-YTLR-----IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIV 401 DEGL Y + IV G S S RD DP PG P + R+ V + Sbjct: 24570 DEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP-----PGRPEAIVI---TRNNVTL 24621 Query: 402 TWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVN 461 WK P S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N Sbjct: 24622 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 24681 Query: 462 SAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD---LEGDAQVPGPPTGV 517 +AG S PS S A+ A D +D ++ + + I ++ + LE D + P V Sbjct: 24682 AAGNFSEPSDSSGAITARDEIDAPNA-SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV 24740 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM- 576 + + GK+ +E++ R+ ++ ++ V D + Sbjct: 24741 WSKD----------------GKE-----LEETAA------RMEIKSTIQKTTLVVKDCIR 24773 Query: 577 -EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRP 635 +G Y+ ++ + G ++ IT ++ D P P +V T + W+ P Sbjct: 24774 TDGGQYILKLSNV---GGTKSIPIT--VKVLDRPGPPEGPLKVTGV--TAEKCYLAWNPP 24826 Query: 636 KHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMS 693 + ++ Y ++ W + + N + V L G +YIFRV AVN G+ Sbjct: 24827 LQDGGANISHYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIG 24885 Query: 694 ENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 E ES + P P + SM + W P GG+ I GY L+KR+ Sbjct: 24886 E-PLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKE 24944 Query: 754 HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPE 812 W + N L V GLTEG YEF++AA N AG+GEPS+PS ++ C+A + Sbjct: 24945 GVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA--LYP 25002 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTT-TANRY 871 PGP + + +S+ + W P+Y G +PV GY V+ +E A EW T T + Sbjct: 25003 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 25062 Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLG-- 929 V+ L++ Y FR+ A+N+ GVG+P+ V+ + R EI D + + L Sbjct: 25063 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 25122 Query: 930 -----FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 F + + W K+ ++D R +IE + L + N + D G Y++++ Sbjct: 25123 ATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 25180 Query: 985 SDTDGVSSSFV 995 + G ++FV Sbjct: 25181 ENNSGSKTAFV 25191 Score = 187 bits (474), Expect = 8e-47 Identities = 169/652 (25%), Positives = 277/652 (42%), Gaps = 58/652 (8%) Query: 357 IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 IV G S S RD DP PG P + R+ V + WK P S + Sbjct: 22420 IVGIGKPSKVSECYVARDPCDP-----PGRP---EAIIVTRNSVTLQWKKPTYDGGSKIT 22471 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI-SRPSRVSDA 474 GY V++ E+ W++ + + + VTGL E Y FRV A N+AG+ S PS + A Sbjct: 22472 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 22531 Query: 475 VAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPP 534 + A D +D R+ + + + + DA + G P + W Sbjct: 22532 ITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-----------IQWI-- 22578 Query: 535 TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLS 594 +G L + + ++ + AVR ++ +Y+ + + ++ Sbjct: 22579 --KGDQELSNTARLEIKSTDFATSLSVKDAVR---------VDSGNYILKAKN-----VA 22622 Query: 595 EPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAG 652 +T ++ D P P V+ S T + W P + D++ Y V+ Sbjct: 22623 GERSVTVNVKVLDRPGPPEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETS 22680 Query: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712 +W + + V L G +Y FR+ AVN G+ E ES+ + + VP Sbjct: 22681 RLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE-PLESEPVVAKNPFVVPD 22738 Query: 713 HPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 P + SM + W+ P GGS ILGY L+KR+ W + L V Sbjct: 22739 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 22798 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVM 831 GL E YEF+++A N AG+ EPS PS + K C+ + +PGP + ++ +S+ + Sbjct: 22799 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDITRSSVFL 22856 Query: 832 LWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKTYVFRVRAV 890 W P+Y G + GY V+ + GEW T N+ ++V L + Y FR+ A+ Sbjct: 22857 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 22916 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG--NIYLG-----FDCQEMTDASQFTW 943 N GVG+ +D P++VE + +I ++ + NI G F + + W Sbjct: 22917 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 22976 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 K EI D I+ + L L N ++ D G Y++++ ++ G S+FV Sbjct: 22977 GKVDGEIRD--AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 23026 Score = 186 bits (473), Expect = 1e-46 Identities = 191/764 (25%), Positives = 296/764 (38%), Gaps = 106/764 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++ S++V +K+ + G P P + W KDG + Q + + + + T Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT---RINVTDSLDLTT 23286 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I DD Y N GQ + + +V + P P Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTASIEIVT----------------LDKPDPPKGPV 23330 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 DV E++TL + ++ RD + W + Sbjct: 23331 KFDDV------------SAESITLSWNPPLYTGGCQITNYIVQKRDTT---TTVWDVVSA 23375 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-------GAPGAP 386 + +L + L E + + +R G S F ++DP+V G PG P Sbjct: 23376 TVARTTLKVTKLKTGTEYQFRIFAENRYGQS------FALESDPIVAQYPYKEPGPPGTP 23429 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 ++D +++ W P SPV+GY ++R E + W + N + ++ Sbjct: 23430 F---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN 23486 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L EG Y FRV A N G+ + S+ S+ A DP D Sbjct: 23487 LEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD------------------------ 23522 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAV 565 PG P + + RN + L W P G + Y +EK + G W + + T V Sbjct: 23523 ---PPGTPEPI---MVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF-TNV 23575 Query: 566 RSPRYAVFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 ++ V L E + Y FRV++ N G +S+PS+ T PI A+D +P R+ Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP----RISMDPKF 23631 Query: 625 KTSVVVQ-WDRPKHEEDLLGYYVDCC--VAGTNLWEP---CNHKPIGYNRFVVHG---LT 675 + ++VV + + E D+ G + + G E C K + ++ Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 23691 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G QYI R A N G V+ P G+T C +L W P Sbjct: 23692 DGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC-----SLTWSPPL 23744 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I Y ++KRE W V +S L V L EG+ Y F+I AVN G+GE Sbjct: 23745 QDGGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 23803 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + + + PGP L + S+ + W P G S + GY V+ R+ Sbjct: 23804 PLESAPVLMKNPFVL--PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRS 23861 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPS 899 WI N+ + L+V+ L + Y FRV A NA GVG+PS Sbjct: 23862 GIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 23905 Score = 186 bits (471), Expect = 2e-46 Identities = 169/660 (25%), Positives = 282/660 (42%), Gaps = 64/660 (9%) Query: 352 LYTLRIVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 +Y IV G S +S RD DP PG P + R+ + + W P Sbjct: 23497 VYAENIVGVGKASKNSECYVARDPCDP-----PGTPEPIM---VKRNEITLQWTKPVYDG 23548 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPS 469 S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N+AG IS+PS Sbjct: 23549 GSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 23608 Query: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529 + + A D ++L R+ + + + +A V G P + Sbjct: 23609 DSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT-----------I 23657 Query: 530 SWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W RG + + + + + A+R ++G Y+ R + Sbjct: 23658 EWL----RGDKEIEESARCEIKNTDFKALLIVKDAIR---------IDGGQYILRASN-- 23702 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 ++ ++ D P P +V + K S+ W P + D+ Y V+ Sbjct: 23703 ---VAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT--WSPPLQDGGSDISHYVVE 23757 Query: 648 CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707 W + + N V L G +Y+FR+ AVN G+ E + + V+ ++ Sbjct: 23758 KRETSRLAWTVVASEVVT-NSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL-MKNP 23815 Query: 708 LTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP 767 +P P + + N SMT+ W P GGS I+GY ++KR+ W + N Sbjct: 23816 FVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD 23875 Query: 768 TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRD 826 L V GLTE YEF+++A N AG+GEPS + ++K C+ + +PGP + + Sbjct: 23876 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD--PVFKPGPPTNAHIVDTTK 23933 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW-ITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W P+Y G S + GY V+ + D EW I QT ++S L + + Y Sbjct: 23934 NSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKI 23993 Query: 886 RVRAVNANGVG---------KPSDTSE-PVLVEARPGTKEISAGVDEQGNIYLGFDCQEM 935 RV A+N G+G KP D E P L K I I++ F + Sbjct: 23994 RVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPF---KG 24050 Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + TW + E +D + +IE ++++L + N D+ D G Y + + ++ G S+FV Sbjct: 24051 RPTPEITWSREEGEFTD--KVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 24108 Score = 186 bits (471), Expect = 2e-46 Identities = 189/804 (23%), Positives = 332/804 (41%), Gaps = 87/804 (10%) Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP-IGLPLSSMIPYTHFDVQFLEKFG 285 + A NA G +S + VV G S G P I LPL YT Sbjct: 26840 FRVFARNAVGSISNPSEVV-----GPITCIDSYGGPVIDLPLE----YTE---------- 26880 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHL 345 V R G +V L+ + P P EWY+DD L+ + + AS+ Sbjct: 26881 VVKYRAGTSVKLRAGISGKP-----APTIEWYKDDKELQTNALVCVENTTDLASILIKDA 26935 Query: 346 HKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + + G Y L++ R + SA + V+ D G PG P++ + A + + + W+P Sbjct: 26936 DRLNSGCYELKL--RNAMGSASATIRVQILDK--PGPPGGPIEFKTVTAEK--ITLLWRP 26989 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + + Y V++ E W ++ ++ C T + +G YIFRVRAVN GI Sbjct: 26990 PADDGGAKITHYIVEKRETSRVVWSMVSEH-LEECIITTTKIIKGNEYIFRVRAVNKYGI 27048 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P SD+V A + PGPP ++I++N Sbjct: 27049 GEPLE-SDSVVAKNAF---------------------------VTPGPPGIPEVTKITKN 27080 Query: 526 YVVLSWEPP-TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 + + W P G D YF+EK S W +V +T +R R V L E Y +R Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET-IRDTRQKVTGLTENSDYQYR 27139 Query: 585 VLSANRHG---LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--E 639 V + N G SEPSE +A D P P ++ + +TK+S+ + W +P ++ Sbjct: 27140 VCAVNAAGQGPFSEPSEF---YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGS 27196 Query: 640 DLLGYYVDCCVAGTNLWEPCNHK-PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 + GY V+ W + K + +VV L G Y FRV AVN G E + Sbjct: 27197 AVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM 27256 Query: 699 SDVIKVQAALTVPSHPYGITL----LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 ++ ++ + L P + L + G + + +P P + + D++ + Sbjct: 27257 NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV--LIPFKGRPPPTVTWRKDEKNLGS 27314 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 + + ++ S ++LT+ +T ++ + N G+GEP + K + P Sbjct: 27315 DARYSIENTDSS-SLLTIPQVTRNDTGKYILTIEN--GVGEPKSSTVSVK----VLDTPA 27367 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 L V ++ +LW P+ G SP+ Y ++ R+ W V+ ++ + K+ Sbjct: 27368 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSF-KL 27426 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPG-TKEISAGVDEQGNIYLGFDCQ 933 DL + + FRV A N G+G+P +T+EPV P +++S + ++ L + Sbjct: 27427 IDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKP 27486 Query: 934 EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993 + S T + ++ + + ++ + ++ + + V + G+S Sbjct: 27487 DFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 27546 Query: 994 FVLDPEELERLMALSNEIKNPTIP 1017 + P ++ L+ ++ E+ IP Sbjct: 27547 VTIGPITVKELI-ITPEVDLSDIP 27569 Score = 185 bits (470), Expect = 2e-46 Identities = 164/638 (25%), Positives = 263/638 (41%), Gaps = 91/638 (14%) Query: 381 GAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC 440 G PG P + + ++ V+WK P S + GY V+R E + WV+ PV Sbjct: 20570 GPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDL 20629 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 + VTGL EG +Y FRV A N AGI PS SD+V D Sbjct: 20630 RCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA-------------------- 20669 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 A PGPP+ H ++ ++ L+W +P G + Y +E VG +W + Sbjct: 20670 -------AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 20722 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGR 617 TA+R ++ V DL + Y FR+ + N G+ EP+ I DV +V AP Sbjct: 20723 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIP------DVEIVEREMAPDF 20776 Query: 618 VLASRNTKTSVVVQW----------DRPKHE----EDLLGYYVDCCVAGTNLWE-----P 658 L + +T VV RP E +D + + T + Sbjct: 20777 ELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPE 20836 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT 718 CN G + + V+ ++ G N + +D+ K Sbjct: 20837 CNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK--------------- 20881 Query: 719 LLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 S+TL W +P GGS I Y ++KRE K++ + K T V GL+EG Sbjct: 20882 ------DSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLSEG 20934 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 Y F++ A N GIGEP++ +E K P P L ++ +++ + W P + Sbjct: 20935 CEYFFRVMAENEYGIGEPTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKH 20990 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G S ++GY ++ + + + +W + TT V +L +G+ Y F+V AVN+ G P Sbjct: 20991 DGGSKITGYVIEAQRKGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 21048 Query: 899 SDTSEPVLVEARPGTKEISA-GVDEQGNIYLGFDCQEMT------DASQFTWCKSYEEIS 951 + S PV+V+ + E+ G+ ++ I D ++ TW K + + Sbjct: 21049 RE-SRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK 21107 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 +R ET + L + + D G Y ++ + G Sbjct: 21108 QTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG 21145 Score = 185 bits (470), Expect = 2e-46 Identities = 164/623 (26%), Positives = 257/623 (41%), Gaps = 58/623 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P + D R+ V ++W+ P S ++GY V+ G++ W C A VK+ + Sbjct: 22049 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEA 22106 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 +TGL +G Y FRV A N GIS P ++S V A D L A L + + Sbjct: 22107 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---LVIPPAFKLLFNTFTVLAGE 22163 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQ 562 DL+ D G PT ++W K V RVNA+ Sbjct: 22164 DLKVDVPFIGRPTPA-----------VTWH---------------KDNVPLKQTTRVNAE 22197 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PSAP-GRVL 619 + + + D + V N G I+ +V V+ P P G V Sbjct: 22198 STENNSLLTIKDACREDVGHYVVKLTNSAG--------EAIETLNVIVLDKPGPPTGPVK 22249 Query: 620 ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTG 677 T S+ + W PK++ + Y V+ T W+ + + L TG Sbjct: 22250 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-ATVARTTIKACRLKTG 22308 Query: 678 EQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFS 737 +Y FR+ A N G S + Q VP P + SM + W P Sbjct: 22309 CEYQFRIAAENRYGKSTYLNSEPTV-AQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISD 22367 Query: 738 GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPS 797 GGS ++GY+L+++E + W ++N +P T GL EG YEF+++A N+ GIG+PS Sbjct: 22368 GGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPS 22427 Query: 798 DPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAG 857 SE + P P + V S+ + WK P Y G S ++GY V+ +E G Sbjct: 22428 KVSECYVARDPCDPPGRPEAII----VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 22483 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLVEARPGTKEI 916 W+ + T + + +V+ L + Y FRV A NA GV +PS+++ + I Sbjct: 22484 RWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRI 22543 Query: 917 SAGVDEQGNIYLGFDCQEMTDASQF-------TWCKSYEEISDDERFKIETVGDHSKLYL 969 S + I + DA + W K +E+S+ R +I++ + L + Sbjct: 22544 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603 Query: 970 KNPDKEDLGTYSVSVSDTDGVSS 992 K+ + D G Y + + G S Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERS 22626 Score = 185 bits (469), Expect = 3e-46 Identities = 198/834 (23%), Positives = 347/834 (41%), Gaps = 94/834 (11%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +++L ++G P P V W K+ P K RI+ LEI A +D YS Sbjct: 17235 TLRLSAIIKGVPFPKVTWKKE-----DRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 17289 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 N G + + V+V ++P G P L +S + R Sbjct: 17290 TVENPAGSKTVSVKVLVL-----DKP----GPPRDLEVSEI------------------R 17322 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 ++ +T K + D V R DV ++W+ + + S HL++ + Sbjct: 17323 KDSCYLTWKEPL---DDGGSVITNYVVERRDVA--SAQWSPLSATSKKKSHFAKHLNEGN 17377 Query: 350 EGLYTLRIVSRGGVSDHSAFLF----VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + L+ + ++ G F+ ++ DPL PG P DL D ++ V + W Sbjct: 17378 QYLFRVAAENQYG---RGPFVETPKPIKALDPL--HPPGPPKDLHHVDVDKTEVSLVWNK 17432 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P+ SP+ GY V+ E GT +W++ C VTGL +G++Y FRV+A N G+ Sbjct: 17433 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV--VTGLQQGKTYRFRVKAENIVGL 17490 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P P++ + + V E ++ + +EG G T V I R Sbjct: 17491 GLPDTTI-------PIECQE-KLVPPSVELDVKL----IEGLVVKAG--TTVRFPAIIRG 17536 Query: 526 YVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRV 585 P P K + + S + + + +T S + + + + +++ Sbjct: 17537 V-------PVPTAK----WTTDGSEIKTD--EHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643 +N G + + DV P+ P +L T + + W PK + ++ Sbjct: 17584 TVSNAAG---SKTVAVHLTVLDVPGPPTGPINILDV--TPEHMTISWQPPKDDGGSPVIN 17638 Query: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 Y V+ + W + + H L G +Y+FRV+A N +G+ + + Sbjct: 17639 YIVEKQDTRKDTWGVVSSGSSKTKLKIPH-LQKGCEYVFRVRAENKIGVGPPLDSTPTV- 17696 Query: 704 VQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + + PS P + + ++ T+ W +PK GGSPI GYY+++REV K W VN + Sbjct: 17697 AKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVNKT 17755 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 P V GL EG+ YEF++ A NLAG+ +PS S+ K P PGP + + Sbjct: 17756 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKP-PGPPINPKLKD 17814 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKT 882 + ++W P+ G SP+ GY V+ ++ +W +N+ + +V L +G Sbjct: 17815 KSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNE 17874 Query: 883 YVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNIYLGFDCQEMTDAS- 939 Y FR++A N G G+P + +E V+ + P E+ + + +G + + Sbjct: 17875 YRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKG 17934 Query: 940 ----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 TW K + + ++R + +L +K + D G Y +S ++ G Sbjct: 17935 RPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 17988 Score = 185 bits (469), Expect = 3e-46 Identities = 204/870 (23%), Positives = 337/870 (38%), Gaps = 134/870 (15%) Query: 161 RSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 ++H V S++L QG PTP W K S + A+ I + TL + + Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHTTDSFSTLTVENCN 28419 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFR-------SVGLPIGLPLSSMIPY 273 +D Y+ N G S V V G P S L PL Sbjct: 28420 RNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGAR 28479 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 H V +EK + RR + ++ KCT + Sbjct: 28480 IHHYV--VEKREAS-RRSWQVISEKCTRQI------------------------------ 28506 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV-TGAPGAPMDLQCH 392 + L + + + V+ GV + +P+V T P P L Sbjct: 28507 ------FKVNDLAEGVPYYFRVSAVNEYGVGEPYEM-----PEPIVATEQPAPPRRLDVV 28555 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 D ++ ++ W P+ S + GY ++ + G++ WV+ K + V L E Sbjct: 28556 DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTFTVERLVEKTE 28613 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y FRV+A N AG S P +V +P +E ++ + L G Sbjct: 28614 YEFRVKAKNDAGYSEPREAFSSVIIKEP---------QIEPTADLTGITNQLI--TCKAG 28662 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + R ++W+ R K+ RV+ T V Sbjct: 28663 SPFTIDVPISGRPAPKVTWKLEEMRLKET---------------DRVSITTTKDRTTLTV 28707 Query: 573 FDLMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 D M G S + + N G + P +T PI+ V+ Sbjct: 28708 KDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSA------------ 28755 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 S V+ W PK ++ Y V+ +GT W+ N + + V LT +Y Sbjct: 28756 ---ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEY 28811 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 FRV + N G+S+ + + +I + PS P + + ++M++ W+ P GGS Sbjct: 28812 SFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGS 28870 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I+GY+++K+E + W + N P V GL EG Y+F+ A+N AG+ + S+ S Sbjct: 28871 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 28930 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFR---EEDAG 857 + + PG +V +++ ++W AP Y G S V GY ++ + E G Sbjct: 28931 RPIMAQN-PVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 28986 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLV--EARPGTK 914 W+ N T ++ + V+ L +G TY FRV A NA GV K S+++ PV E P Sbjct: 28987 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 29046 Query: 915 EISAGV-DEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 E+ A + + I G D + DA+ + W K +E+ E+ ++ G + Sbjct: 29047 ELDARLHGDLVTIRAGSDL--VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT 29104 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFVL 996 +K D+ D G Y+++V + G + V+ Sbjct: 29105 AVIKFCDRSDSGKYTLTVKNASGTKAVSVM 29134 Score = 184 bits (466), Expect = 7e-46 Identities = 162/629 (25%), Positives = 274/629 (43%), Gaps = 63/629 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG +DL+ ++ + WK P++ S ++GY VD N W + + +Y Sbjct: 19884 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKS--LSLQY 19940 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVS----DAVAALDPLDLRRLQAVHLEGEKEIA 498 L EG+ Y FRV A N G PS ++ D V A D LDL+ L + Sbjct: 19941 SAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPD-LDLKGLPDL--------- 19990 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 Y + ++ P G A +S W+ +G+DPL + R Sbjct: 19991 CYLAKENSNFRLKIPIKGKPAPSVS-------WK----KGEDPL-----------ATDTR 20028 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V+ +++ + V+D + + + + N G E T I+ +P+ P + Sbjct: 20029 VSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG---TISIKVVGKPGIPTGP--I 20083 Query: 619 LASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTT 676 T ++ ++W PK + ++ Y ++ + N W C + F V L Sbjct: 20084 KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCA-SAVQKTTFRVTRLHE 20142 Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +Y FRV A N G+ E + S+ I + VP P +++ S++L W PK Sbjct: 20143 GMEYTFRVSAENKYGVGEGLK-SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKK 20201 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 +GGSPI GY+L+ +E + W N +P + V GLTEG YEF++ A+NLAG+G+P Sbjct: 20202 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 20261 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S PSE + P + S+ ++W P Y G ++GY V+ R+ + Sbjct: 20262 SLPSE----PVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPS 20317 Query: 857 GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVN-ANGVGKPSDTSEPVLV--EARPGT 913 W+ N V+DL +G Y FR+RA N A + PS+++E ++ E T Sbjct: 20318 KSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPT 20377 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 + + + I G D + S + +W K+ ++I + +I + S Sbjct: 20378 IVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 20436 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 L +K ++D G Y+++ ++ G V Sbjct: 20437 LTIKYATRKDAGEYTITATNPFGTKVEHV 20465 Score = 184 bits (466), Expect = 7e-46 Identities = 157/633 (24%), Positives = 259/633 (40%), Gaps = 56/633 (8%) Query: 283 KFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSF 342 K G+T + G+T+ L ++ L P++ W + ++ S T++ + L+ Sbjct: 20385 KDGLTIKA-GDTIVLNAISILGKPL----PKSSWSKAGKDIRPSDITQITSTPTSSMLTI 20439 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + + D G YT+ + G V V PG P ++ + + + +T Sbjct: 20440 KYATRKDAGEYTITATNPFGTK-------VEHVKVTVLDVPGPPGPVEISNVSAEKATLT 20492 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W PP SP+ Y +++ E W ++ ++ C++ T L +G YIFRV AVN Sbjct: 20493 WTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNH 20551 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 G P + S+ V +D PGPP S + Sbjct: 20552 YGKGEPVQ-SEPVKMVDRFG---------------------------PPGPPEKPEVSNV 20583 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 ++N +SW+ P G + Y +E+ S W R +T V R V L EG +Y Sbjct: 20584 TKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTY 20642 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE-- 639 FRV + NR G+ PSE + + +D P P + TK S + W +P ++ Sbjct: 20643 EFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGL 20702 Query: 640 DLLGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 ++ GY V+ G W + + +FVV L T E+Y FR+ A+N G+ E + Sbjct: 20703 EITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 20762 Query: 699 SDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWH 758 DV V+ + P L L ++ G P K ++ KN Sbjct: 20763 PDVEIVEREM-APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRA 20821 Query: 759 EVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818 + ++ S T+L + +F + N AG + + PGP + Sbjct: 20822 NIENTESF-TLLIIPECNRYDTGKFVMTIENPAG-------KKSGFVNVRVLDTPGPVLN 20873 Query: 819 LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQ 878 L ++ S+ + W P+ G S ++ Y V+ RE + T Y KV+ L Sbjct: 20874 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLS 20932 Query: 879 QGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP 911 +G Y FRV A N G+G+P++T+EPV P Sbjct: 20933 EGCEYFFRVMAENEYGIGEPTETTEPVKASEAP 20965 Score = 184 bits (466), Expect = 7e-46 Identities = 233/952 (24%), Positives = 374/952 (39%), Gaps = 107/952 (11%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR---CEVGTNNWVQCNDAPVK 438 APG P + D R V + W P S V+GY ++R EVG W++CN V Sbjct: 28941 APGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 28997 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQA-VHLEGEKE 496 + VT L EG +Y FRV A N+AG IS+ S + V D + + L G+ Sbjct: 28998 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 29057 Query: 497 IAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK-DPLMYFIEKSVVGSGS 555 DL DA V G P EP K D + EK Sbjct: 29058 TIRAGSDLVLDAAVGGKP-----------------EPKIIWTKGDKELDLCEK------- 29093 Query: 556 WQRVNAQ-TAVRSPRYAVF-DLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS 613 V+ Q T R+ F D + Y V +A+ G S + + + P Sbjct: 29094 ---VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNAS--GTKAVSVMVKVLDS------PG 29142 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV 671 G++ SR T+ + W P+ + ++ Y V+ W + + +VV Sbjct: 29143 PCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVV 29201 Query: 672 HGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGW 731 L +YIFRV+AVN G ES+ I + + T+PS P + + + W Sbjct: 29202 TRLIKNNEYIFRVRAVNKYGPGV-PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQW 29260 Query: 732 KVPKFSGGSPILGYYLDKREVHHKNWHEVNSS-PSKPTILTVDGLTEGSLYEFKIAAVNL 790 P+ GG+ I Y +DKRE W VN T L V L EG Y+F++ AVN Sbjct: 29261 TKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNA 29320 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 AG EPS+ S C + PGP + S+ + W P+Y G + + GY ++ Sbjct: 29321 AGNSEPSEASNFISCREPSYT-PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 29379 Query: 851 FREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT---SEPVL 906 +E+D +W V+ T N V DL+ G+ Y FRV AVN G+ + S++ EPV Sbjct: 29380 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 29439 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETV 961 P E++ + + I G + M S TW K +++ R I+T Sbjct: 29440 RIEIPDL-ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTT 29496 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSE 1021 +S L + ++ D G Y++ + G S+ VL ++ + P S Sbjct: 29497 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL------------VKVYDTPGPCPSV 29544 Query: 1022 LAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRI--KCDKA----TGIIEM 1075 E+ W +I+ RE + + KC K +G++E Sbjct: 29545 KVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEG 29604 Query: 1076 VMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEY 1135 M F + E Y + G+ S VL+ + L A+ + + + Sbjct: 29605 TMYYFRVLPENIYGI----GEPCETSDAVLVSE---VPLVPAKLEVVDVTKS-----TVT 29652 Query: 1136 LHWD-VTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKD 1194 L W+ + RL V K +W+K + L+ + E + L++ + Sbjct: 29653 LAWEKPLYDGGSRLTGYVLEACKAGTERWMK---------VVTLKPTVLEHTVTSLNEGE 29703 Query: 1195 HGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMK 1254 ++ ++++G + D L + S P K + P G ++ + Sbjct: 29704 QYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTIDLSTMPQKTIHVPAGRPVELVIP 29761 Query: 1255 YF-TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEI 1305 +W +K+ SE + + ++A L I E T +D G+YT E+ Sbjct: 29762 IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 29813 Score = 182 bits (462), Expect = 2e-45 Identities = 157/621 (25%), Positives = 254/621 (40%), Gaps = 75/621 (12%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 LV P R P A W+ L+ES+ + A L+ D G YTL + + Sbjct: 29758 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 29817 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G + + + + D G P P+ + DA + ++W+PP +P+ GY V++ Sbjct: 29818 GTTSETIKVIILDKP----GPPTGPIKIDEIDATS--ITISWEPPELDGGAPLSGYVVEQ 29871 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 + W+ +++ + + T L EG Y+FRV A N GI Sbjct: 29872 RDAHRPGWLPVSESVTR-STFKFTRLTEGNEYVFRVAATNRFGIGS-------------- 29916 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 LQ+ +E I ++PGPP + ++SR+ + L+W PP G Sbjct: 29917 ---YLQSEVIECRSSI-----------RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ 29962 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ V + W RVN + V RY L EG Y RV + N G +PS + Sbjct: 29963 VTGYIVERKEVRADRWVRVN-KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 30021 Query: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEP 658 PI A D P P + T+TSV + W P+ E + GY ++ + W Sbjct: 30022 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 30081 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY--- 715 CN P + + L G +Y FRV A NA G E ++ +KV L P + Sbjct: 30082 CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDER 30141 Query: 716 ---GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 GI + +T+ K F PI + + +++ + + + ++ I Sbjct: 30142 YQEGIFVRQGGVIRLTIPIKGKPF----PICKWTKEGQDISKRAMIATSETHTELVIKEA 30197 Query: 773 DGLTEGSLYEF--------KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEV 824 D G+ Y+ K + + IG P+ P GP L + ++ Sbjct: 30198 DRGDSGT-YDLVLENKCGKKAVYIKVRVIGSPNSPE-------------GP---LEYDDI 30240 Query: 825 RDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 + S+ + W+ P G + + GY ++ RE W T++ L V L++ Y Sbjct: 30241 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTS-LVVKGLKENVEYH 30299 Query: 885 FRVRAVNANGVGKPSDTSEPV 905 FRV A N G+ KP + EPV Sbjct: 30300 FRVSAENQFGISKPLKSEEPV 30320 Score = 182 bits (461), Expect = 3e-45 Identities = 173/685 (25%), Positives = 271/685 (39%), Gaps = 56/685 (8%) Query: 238 VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS----SMIPYTHFDVQFLEKFGVTFRREGE 293 VS N V GD FR + +S S P T D K + R G+ Sbjct: 28996 VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 29055 Query: 294 TVTLKCTMLVTPDLK---RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 VT++ + D + +P+ W + D L + + + +A+ + D Sbjct: 29056 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 29115 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G YTL + + G S + V D+ PG L ++ + W P Sbjct: 29116 GKYTLTVKNASGTKAVSVMVKVLDS-------PGPCGKLTVSRVTQEKCTLAWSLPQEDG 29168 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y V+R E NWV + Y VT L + YIFRVRAVN G Sbjct: 29169 GAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAVNKYG------ 29221 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 V +E E +A +P PP + ++++ Sbjct: 29222 ----------------PGVPVESEPIVA------RNSFTIPSPPGIPEEVGTGKEHIIIQ 29259 Query: 531 W-EPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W +P + G + Y ++K S W RVN V R V LMEG Y FRV + N Sbjct: 29260 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 29319 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G SEPSE ++ I ++ + P P TK S+ + W +P ++ D++GY ++ Sbjct: 29320 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 29379 Query: 648 CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 T+ W + + I F V L G++Y FRV AVN GMSE S+ I+ Sbjct: 29380 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 29439 Query: 707 ALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK 766 + +P L ++ G P K+ + + ++++ S Sbjct: 29440 RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY 29499 Query: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826 ++L VD + ++ I A N +G + PGP + EV Sbjct: 29500 -SLLIVDKVNRYDAGKYTIEAENQSG-------KKSATVLVKVYDTPGPCPSVKVKEVSR 29551 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFR 886 S+ + W+ P G +PV+ Y V+ RE + TV + Y ++S L +G Y FR Sbjct: 29552 DSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLY-RISGLVEGTMYYFR 29610 Query: 887 VRAVNANGVGKPSDTSEPVLVEARP 911 V N G+G+P +TS+ VLV P Sbjct: 29611 VLPENIYGIGEPCETSDAVLVSEVP 29635 Score = 181 bits (460), Expect = 4e-45 Identities = 159/669 (23%), Positives = 274/669 (40%), Gaps = 82/669 (12%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ PG P + + D R V + W P S V GY ++ +V + W +CN Sbjct: 30028 DPIAP--PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 30085 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR--RLQAVHLEG 493 P KI +Y +T L +G Y FRV A N+ G P+ V V + L+ L + EG Sbjct: 30086 PTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEG 30145 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGS 553 I + Q G ++ P G + + + W T G+D I K Sbjct: 30146 ---IFVRQG---GVIRLTIPIKG-------KPFPICKW---TKEGQD-----ISK----- 30179 Query: 554 GSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHG----------LSEPSEITSPI 603 R T+ + + G S + ++ N+ G + P+ P+ Sbjct: 30180 ----RAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 30235 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 + D+ V SV V W P + D+LGY ++ W + Sbjct: 30236 EYDDIQV---------------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 30280 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT-LL 720 + G + VV GL +Y FRV A N G+S+ + + + + L P P +L Sbjct: 30281 RVRGTS-LVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVL 30339 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + S++L W PK GGS + GYY++++E W N + T+ TV GL + Sbjct: 30340 DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAE 30399 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G+ E S SE C+ +P +L + S+ + W+ P G Sbjct: 30400 YQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSISKDSVTLQWEKPECDG 30458 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + GY+V++R+ W N+ ++ + L + Y FRV A N G+ +P Sbjct: 30459 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 30518 Query: 901 TSEPVLVEARPG--------TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 T+ + + G K+++ + E + + + D W + +E+ Sbjct: 30519 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD---IKWYRFGKELIQ 30575 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 ++K+ + G L + ++ED G Y+ ++++ V + E +L+ + Sbjct: 30576 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGEVETSSKLLLQATPQF 30628 Query: 1013 NPTIPLKSE 1021 +P PLK + Sbjct: 30629 HPGYPLKEK 30637 Score = 179 bits (453), Expect = 2e-44 Identities = 155/603 (25%), Positives = 260/603 (43%), Gaps = 78/603 (12%) Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGA---- 382 +W ++ G L + E + +R V++ G S+ S +DP++ Sbjct: 14029 EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS-----EPSDPVLCREKLYP 14083 Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P L+ + ++ + W P SP+ Y V++ +V W Q D VK K Sbjct: 14084 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKC 14142 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 VT L EG Y+FRV A N+ G S + + D+V A D Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT-------------------- 14182 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA 561 PGPP + ++++ +V L WEPP G P+ Y IEK W + Sbjct: 14183 -------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG- 14234 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +TA + V D++EG F+V + N G+ PSE T + +D T PS P + + Sbjct: 14235 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 14294 Query: 622 RNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH-GLTTGE 678 + + + W P+ ++GY+V+ C GT W N +PI +F V G+ + Sbjct: 14295 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 14354 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQ---AALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +Y+ RV+AVNA+G+SE S+ S+ + + T+ + I ++ +G +++ VP Sbjct: 14355 EYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVI--EGEKLSI--PVPF 14410 Query: 736 FSGGSPILGYYLDKREVHH------KNWHEVNSSPSKPTILTVDGLTEGSLYEFKI---- 785 + P + ++ D +EV KN H +++ P + D E K+ Sbjct: 14411 RAVPVPTVSWHKDGKEVKASDRLTMKNDH-ISAHLEVPKSVRADAGIYTITLENKLGSAT 14469 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 A++N+ IG P GP D+ ++ +S + W+ P + G +P+ Sbjct: 14470 ASINVKVIGLP-----------------GPCKDIKASDITKSSCKLTWEPPEFDGGTPIL 14512 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE +I V + V DL Y FRV+AVN G G+ + PV Sbjct: 14513 HYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV 14571 Query: 906 LVE 908 + + Sbjct: 14572 IAQ 14574 Score = 177 bits (450), Expect = 5e-44 Identities = 166/627 (26%), Positives = 257/627 (40%), Gaps = 66/627 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK- 441 PG P + D + V + W P S ++GYFV+ C++ + WV+CN AP +I + Sbjct: 19193 PGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 19249 Query: 442 -YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 Y TGL E Y FR A + IS PS SD V L A ++ ++++ Sbjct: 19250 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL---------AENVPPRIDLSVA 19300 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVN 560 L G + A+ + +SW+ KD + K G + N Sbjct: 19301 MKSLL--TVKAGTNVCLDATVFGKPMPTVSWK------KDGTLL---KPAEGIKMAMQRN 19349 Query: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 T +F + S + + + N G T ++ D P P V Sbjct: 19350 LCTL------ELFSVNRKDSGDYTITAENSSG---SKSATIKLKVLDK---PGPPASVKI 19397 Query: 621 SRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 ++ ++ W+ P + ++ Y VD W + + V L G Sbjct: 19398 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVS-ATVPITSCSVEKLIEGH 19456 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI----TLLNCDGHSMTLGWKVP 734 +Y FR+ A N G+ + V A P P G + N MT+ WK P Sbjct: 19457 EYQFRICAENKYGVGD-----PVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPP 19511 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 GGSPI GY L+KRE NW +VN P L GL EG+ YEF++ A+N AG G Sbjct: 19512 ADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPG 19571 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PSD S+ P PA+ + R +S+ + W P Y G SP+ GY V+ + Sbjct: 19572 KPSDASKAAYARDPQYPPGPPAFPKVYDTTR-SSVSLSWGKPAYDGGSPIIGYLVEVKRA 19630 Query: 855 DAGEWITVN--QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLV 907 D+ W+ N Q R+ +V+ L + Y FRV AVN G PSD + +L+ Sbjct: 19631 DSDNWVRCNLPQNLQKTRF-EVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 19689 Query: 908 EARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVG 962 P E+ A + + + G + + TW K + D I++ Sbjct: 19690 ---PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD 19746 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L +N +K D G Y +++ ++ G Sbjct: 19747 FDTFLRCENVNKYDAGKYILTLENSCG 19773 Score = 176 bits (445), Expect = 2e-43 Identities = 164/628 (26%), Positives = 264/628 (42%), Gaps = 59/628 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + + R+ V + W P + GY V++ ++ + +W++ N V C + Sbjct: 20277 PGKP---EVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAF 20333 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 VT L EG Y FR+RA N+AG IS PS ++ + D E E + Sbjct: 20334 TVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD------------EYEAPTIVLD 20381 Query: 502 DDLEGDAQVPGPPTGV--HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 ++ + T V S + + SW + GKD I + + + + + Sbjct: 20382 PTIKDGLTIKAGDTIVLNAISILGKPLPKSSW---SKAGKDIRPSDITQ-ITSTPTSSML 20437 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV--VPSAPGR 617 + A R A + ++ + + ++ VTV VP PG Sbjct: 20438 TIKYATRK-------------------DAGEYTITATNPFGTKVEHVKVTVLDVPGPPGP 20478 Query: 618 VLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLT 675 V S + + W P + + Y ++ LW + + I R V L Sbjct: 20479 VEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLI 20537 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G +YIFRV AVN G E Q S+ +K+ P P + N ++ T+ WK P Sbjct: 20538 QGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 20596 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I GY++++RE W +P V GL EGS YEF+++A N AGIG Sbjct: 20597 DDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGP 20656 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 PS+ S+ + P PGP + + S + W P Y G ++GY V+ ++ Sbjct: 20657 PSEASDSVLMKDAAYP-PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 20715 Query: 856 AGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGT 913 WI + T TA R + V DLQ + Y FR+ A+N GVG+P+ + +VE Sbjct: 20716 DEAWIK-DTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAP 20774 Query: 914 K-EISAGVDEQGNIYLGFDCQ-----EMTDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 E+ A + + G + + A + TW K + I+ R IE + L Sbjct: 20775 DFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLL 20832 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ D G + +++ + G S FV Sbjct: 20833 IIPECNRYDTGKFVMTIENPAGKKSGFV 20860 Score = 174 bits (442), Expect = 4e-43 Identities = 154/640 (24%), Positives = 249/640 (38%), Gaps = 84/640 (13%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + +++ + V W PP + GYF+++ E + WV N + + + Sbjct: 18396 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 18455 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 V L Y FRV+A N GI PS S V A DP++ Sbjct: 18456 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE-------------------- 18495 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE-KSVVGSGS----W 556 PGPPT + +++ + L W P G P++ Y +E + + S W Sbjct: 18496 -------PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--- 613 +R NA + + V L E + Y FRV + N+ G+ P+E+ I+ +++ P Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608 Query: 614 -------------APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 P R+ A + + V W + + + VD L P + Sbjct: 18609 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNS 18668 Query: 661 HKPIGYNRFVVHGLTTGEQYIF-RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITL 719 + + GE+ +F V+ ++ G + + SDV K Sbjct: 18669 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT--------------- 18713 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGS 779 S + W P+ GGS + Y ++KRE K W V K T V L G+ Sbjct: 18714 ------SCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKK-TSFHVTNLVPGN 18766 Query: 780 LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYS 839 Y F++ AVN G G P+D + + EP P L E+ S + W P+ Sbjct: 18767 EYYFRVTAVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRD 18825 Query: 840 GSSPVSGYFVDFREED--AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G + + GY +REE+ A W + + L V+ L++GK Y FRV A NA GV Sbjct: 18826 GGAKIDGYITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSL 18883 Query: 898 PSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDA-----SQFTWCKSYEEISD 952 P + + EA+ + EQ I G + W K +E+ Sbjct: 18884 PREAEG--VYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVT 18941 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 + S L +K+ ++D G YS++ ++ G + Sbjct: 18942 SSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDT 18981 Score = 173 bits (439), Expect = 1e-42 Identities = 157/607 (25%), Positives = 254/607 (41%), Gaps = 62/607 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + + + S + + + L + + D G Y+L + G + Sbjct: 18928 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 18987 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V DA G P P D+ D + D ++W P S + Y V++C+V +WV Sbjct: 18988 VMDAP----GPPQPPFDIS--DIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVT 19041 Query: 432 CNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490 + K C+ V L G+ YIFRVRA N GIS P Sbjct: 19042 ALASVTKTSCR--VGKLIPGQEYIFRVRAENRFGISEP---------------------- 19077 Query: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKS 549 L K +A + VP P ++++++ + ++W+ P G P++ Y IE+ Sbjct: 19078 LTSPKMVAQFPFG------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK 19131 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W + N T VRS Y L+EG Y FR+ + N+ G S PS+ T + A+ + Sbjct: 19132 ERNSLLWVKAN-DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MP 19189 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 V P PG+ TK++V + W RPKH+ ++GY+V+ C + W CN P I Sbjct: 19190 VDP--PGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 19247 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC--- 722 + GL QY FR A AV +S S+ SD + + A P + + + Sbjct: 19248 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 19307 Query: 723 -DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781 G ++ L V F P + + D + ++ + T L + + Sbjct: 19308 KAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT-LELFSVNRKDSG 19364 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 ++ I A N +G S+ + + +PGP + ++ ++ W+ P+ G Sbjct: 19365 DYTITAENSSG-------SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 19417 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y VD RE W V+ T V L +G Y FR+ A N GVG P T Sbjct: 19418 SEITNYIVDKRETSRPNWAQVSATVPITS-CSVEKLIEGHEYQFRICAENKYGVGDPVFT 19476 Query: 902 SEPVLVE 908 EP + + Sbjct: 19477 -EPAIAK 19482 Score = 172 bits (437), Expect = 2e-42 Identities = 163/628 (25%), Positives = 259/628 (41%), Gaps = 61/628 (9%) Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQ-ASLSFSHLHKDDE 350 GET L+ + P P W +D L+E+ Q +L + D Sbjct: 24722 GETFVLEADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G Y L++ + GG + V D G P P+ + A + Y+ W PP Sbjct: 24777 GQYILKLSNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDG 24830 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y +++ E +W Q + V+ Y VT L G YIFRV AVN GI P Sbjct: 24831 GANISHYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE 24889 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 S V A +P + PGPP+ S I+++ +V++ Sbjct: 24890 -SGPVTACNPY---------------------------KPPGPPSTPEVSAITKDSMVVT 24921 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W P G + Y +EK W + N +T + R V L EG SY FRV + N Sbjct: 24922 WARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAEN 24980 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G+ EPSE + +A D P P + +++SV + W +P ++ + GY V+ Sbjct: 24981 AAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVE 25040 Query: 648 CCVAGTNLWEPCNHKPIGY--NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ 705 A + W C P G +F V L +Y FR+ A+N+ G+ E + + Q Sbjct: 25041 VKEAAADEWTTCT-PPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQ 25099 Query: 706 AALTVPSHPYGITLLNCD--GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + P L S TL V P + + + + + EV SS Sbjct: 25100 ERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS 25159 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 T+L +D +T + + N +G S+ + P +LT E Sbjct: 25160 ---FTMLVIDNVTRFDSGRYNLTLENNSG-------SKTAFVNVRVLDSPSAPVNLTIRE 25209 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTY 883 V+ S+ + W+ P+ G + ++ Y V+ RE + T+ T + ++ +LQ+G +Y Sbjct: 25210 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTF-RIENLQEGCSY 25268 Query: 884 VFRVRAVNANGVGKPSDTSEPVLVEARP 911 FRV A N G+G P++T+EPV V P Sbjct: 25269 YFRVLASNEYGIGLPAETTEPVKVSEPP 25296 Score = 172 bits (436), Expect = 2e-42 Identities = 149/603 (24%), Positives = 243/603 (40%), Gaps = 66/603 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R P W R++ + ++ G LS + ++D G Y L++ + G SA Sbjct: 24051 RPTPEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG--SKSA 24106 Query: 369 FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNN 428 F+ V+ D PG P +L + +D + W+PP + V Y +D+ E Sbjct: 24107 FVTVKVLD-----TPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 24161 Query: 429 WVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488 + + K + V L EG Y FRV A N G+ P DAV A +P Sbjct: 24162 YANVSSKCSKT-SFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-------- 24212 Query: 489 VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE 547 P PP V +++S+ L WE P G ++ Y +E Sbjct: 24213 ----------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 24250 Query: 548 KSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD 607 G+ W V + V L G+ Y FRV + N G S+P + P+ A+D Sbjct: 24251 MQPKGTEKWSIVAESKVCNA---VVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 24307 Query: 608 VTVVPSA-----PGRVLASRNTKTSV-VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH 661 +T+ PS + A + K + V+ RP + G L + Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN---------ISWVKDGEPLKQTTRV 24358 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLL 720 V + G + F V A + + E+ + V L P P G + Sbjct: 24359 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV---LEKPGPPVGPVRFD 24415 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + + W+ P ++GG I Y ++KR+ WH V+++ ++ TI + L G+ Sbjct: 24416 EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTE 24474 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G P D + EPGP + +++ W PV G Sbjct: 24475 YQFRIFAENRYGKSAPLDSKA--VIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG 24532 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + + GY ++ +E+++ W+ +N+T + K + L +G Y F+V A N G+GKPS Sbjct: 24533 GTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 24592 Query: 901 TSE 903 SE Sbjct: 24593 VSE 24595 Score = 172 bits (435), Expect = 3e-42 Identities = 170/703 (24%), Positives = 284/703 (40%), Gaps = 123/703 (17%) Query: 353 YTLRIVSRG--GVSDHSA-FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTT 409 Y R+ + GV + S +F R D L PG P + + D +R V + W P Sbjct: 24972 YEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYD 25029 Query: 410 TESPVMGYFVDRCEVGTNNWVQCNDAP-VKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468 +PV GY V+ E + W C ++ ++ VT L E Y FR+ A+NS G+ P Sbjct: 25030 GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEP 25089 Query: 469 SRVSDAVAALDPL---------DLRRLQA----------VHLEGEKEIAIYQDDLEG--- 506 + + +V A + + DLR++ V ++G E + + EG Sbjct: 25090 ATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 25149 Query: 507 -DAQV--------------------------------------------PGPPTGVHASE 521 AQ+ P P + E Sbjct: 25150 DRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 25209 Query: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++ V LSWEPP G + Y +EK ++ + + + + +L EG S Sbjct: 25210 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT--FRIENLQEGCS 25267 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE-- 638 Y FRVL++N +G+ P+E T P++ V+ P PGRV T+ + ++W++P+ + Sbjct: 25268 YYFRVLASNEYGIGLPAETTEPVK---VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGG 25324 Query: 639 EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ- 697 + GY V+ G+ W C + + GLT GE+Y+FRV AVN G S+ Q Sbjct: 25325 SKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQL 25382 Query: 698 ----ESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 + I+++ ++ +P H + + L VP + + D + + Sbjct: 25383 GVPVIARDIEIKPSVELPFHTFNVKARE------QLKIDVPFKGRPQATVNWRKDGQTL- 25435 Query: 754 HKNWHEVNSSPSKP-TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE 812 K VN S SK T L++ ++ + +++ N AG S + Sbjct: 25436 -KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG-------SITVPITIIVLDR 25487 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872 PGP + EV S+ + W P Y G +S Y V+ +E + W V+Q A + Sbjct: 25488 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSI 25546 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLVEARPGTKEI----------- 916 K+ L G Y FRV A N G S++S P PGT ++ Sbjct: 25547 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVT 25606 Query: 917 -SAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958 V++ G+ +G+ E + S W K+ + + D + K+ Sbjct: 25607 WQVPVNDGGSRVIGYHL-EYKERSSILWSKANKILIADTQMKV 25648 Score = 171 bits (434), Expect = 4e-42 Identities = 161/542 (29%), Positives = 240/542 (44%), Gaps = 50/542 (9%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DPL G P +P L + + + + WK P + SP+ GY +++ ++ + N Sbjct: 15290 DPL--GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 15347 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 + V L E + Y FRV+AVN G S PS + V D + + + G+ Sbjct: 15348 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT 15407 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 + + A V G P + E S+N V+ E PT D L I K V Sbjct: 15408 IKVKAGEPVHIPADVTGLP--MPKIEWSKNETVI--EKPT----DALQ--ITKEEV---- 15453 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PS 613 R A+T + P+ + E K + V ++NR G S + V V PS Sbjct: 15454 -SRSEAKTELSIPK----AVREDKG-TYTVTASNRLG--------SVFRNVHVEVYDRPS 15499 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL--WEPCNHKPIGYNRF 669 P + + S + WD P ++ Y +D A WE + + R+ Sbjct: 15500 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAV-EKRY 15558 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 + L QY FRV+AVN G+S+ +SD + +Q +P P +L SM + Sbjct: 15559 GIWKLIPNGQYEFRVRAVNKYGISDEC-KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLV 15617 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSP-----SKPTILTVDGLTEGSLYEFK 784 W P +GGSPI GY+L+KRE W V+ +P K V L EG Y+F+ Sbjct: 15618 SWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFR 15677 Query: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844 A+N AGIG PS+PS+ P PGP + +S+ + WK P G SP+ Sbjct: 15678 AMAINAAGIGPPSEPSDPEVAGDPIFP-PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPI 15736 Query: 845 SGYFVDFREEDAGEWITVNQ----TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 GY V+ +EE +W VN+ TT V +L++ + Y FRV+AVN G +PSD Sbjct: 15737 KGYIVEMQEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEPSD 15794 Query: 901 TS 902 T+ Sbjct: 15795 TT 15796 Score = 171 bits (433), Expect = 5e-42 Identities = 165/648 (25%), Positives = 245/648 (37%), Gaps = 83/648 (12%) Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL--LKESKWTKMFFGEGQA 338 L+ GV + G+T+ L+ + P P W +D L S K+ + Sbjct: 18205 LKLSGVLTVKAGDTIRLEAGVRGKPF-----PEVAWTKDKDATDLTRSPRVKIDTRADSS 18259 Query: 339 SLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDY 398 S + + D G Y + + G FV A V PG +L+ D + D Sbjct: 18260 KFSLTKAKRSDGGKYVVTATNTAGS-------FVAYATVNVLDKPGPVRNLKIVDVSSDR 18312 Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 V W PP + Y +++CE W A V VT L EG YIFRVR Sbjct: 18313 CTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRLIEGNEYIFRVR 18371 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVH 518 A N G P+ +A + PG P Sbjct: 18372 AENKIGTGPPTESKPVIA----------------------------KTKYDKPGRPDPPE 18403 Query: 519 ASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLME 577 +++S+ + + W PP GK YF+EK S W VN ++A+ R V +L+ Sbjct: 18404 VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN-KSAIPERRMKVQNLLP 18462 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 Y FRV + N G+ EPS + P+ A+D P P TK S+ + W +P + Sbjct: 18463 DHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVY 18522 Query: 638 E--EDLLGYYVD-----CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 + ++GY V+ + W+ CN + F V L ++Y FRV A N Sbjct: 18523 DGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ 18582 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 VG+ ++ + IK + L P ++ K+ G PI + + + Sbjct: 18583 VGIGRPAELKEAIKPKEILEPPEIDLDASMR-----------KLVIVRAGCPIRLFAIVR 18631 Query: 750 -REVHHKNWHEVN----------SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 R W +V L + T ++ + VN AG Sbjct: 18632 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG------ 18685 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + PGP DL +V TS + W P G S V+ Y V+ RE D Sbjct: 18686 -EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKT 18744 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 W TV + V++L G Y FRV AVN G G P+D +PVL Sbjct: 18745 WSTVTPEVKKTSF-HVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVL 18791 Score = 171 bits (433), Expect = 5e-42 Identities = 160/655 (24%), Positives = 271/655 (41%), Gaps = 62/655 (9%) Query: 364 SDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC 422 +++ L + ADP+ V P P + D R+ V ++W P S ++ Y V+ Sbjct: 23111 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 23170 Query: 423 EVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + W +C A VK + +T L +G Y+FRV AVN G S P ++ + A D + Sbjct: 23171 AKHSEKWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV- 23227 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL 542 + + + + Y + D ++ P +G R ++W Sbjct: 23228 ------IEPDVKPAFSSYSVQVGQDLKIEVPISG-------RPKPTITWT---------- 23264 Query: 543 MYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 K + R+N ++ ++ + + + + AN G + T+ Sbjct: 23265 -----KDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-----QKTAS 23314 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCN 660 I+ + G V + S+ + W+ P + + Y V T +W+ + Sbjct: 23315 IEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 23374 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 + V L TG +Y FR+ A N G S + ESD I Q P P Sbjct: 23375 -ATVARTTLKVTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPGPPGTPFAT 23432 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 SM + W P +GGSP++GY+L+++E + W +VN + T L EG Sbjct: 23433 AISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIE 23492 Query: 781 YEFKIAAVNLAGIGEPSDPSEHF----KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 YEF++ A N+ G+G+ S SE + C+ PEP V+ + + W P Sbjct: 23493 YEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEP--------IMVKRNEITLQWTKP 23544 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-V 895 VY G S ++GY V+ R+ G W+ + T VS L + + Y FRV A NA G + Sbjct: 23545 VYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAI 23604 Query: 896 GKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYE 948 KPSD++ P+ + IS + I + +A W + + Sbjct: 23605 SKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDK 23664 Query: 949 EISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EI + R +I+ + L +K+ + D G Y + S+ G S SF ++ + L+R Sbjct: 23665 EIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG-SKSFPVNVKVLDR 23718 Score = 170 bits (431), Expect = 8e-42 Identities = 168/685 (24%), Positives = 281/685 (41%), Gaps = 86/685 (12%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R +P W +D LK++ + L +KDD G YT+ + G + Sbjct: 24334 PVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 24393 Query: 365 DHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 + + V + PG P+ ++ + + D+V+++W+PP T + Y V++ + Sbjct: 24394 TENLSVIVLEK-------PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 24446 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDL 483 T W + A V +T L G Y FR+ A N G S P Sbjct: 24447 TTTTTWHMVS-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP--------------- 24490 Query: 484 RRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM 543 L+ + I Y + PGPP + IS++ +++ W P G ++ Sbjct: 24491 -------LDSKAVIVQYP------FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKII 24537 Query: 544 -YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 Y +E+ S W ++N +T ++ ++ L EG Y F+V + N G+ +PS+++ Sbjct: 24538 GYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSEC 24596 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCN 660 A+D P P ++ +RN +V ++W +P ++ + GY V+ W + Sbjct: 24597 FVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 24653 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPS----HPY 715 + F V GL ++Y FRV A NA G SE S S I + + P+ Y Sbjct: 24654 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 24713 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWH-EVNSSPSKPTILTV 772 ++ G + L + G PI + + D +E+ E+ S+ K T++ Sbjct: 24714 KDVIVVHAGETFVLEADI----RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVK 24769 Query: 773 DGL-TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 D + T+G Y K++ V G S P + PGP L V Sbjct: 24770 DCIRTDGGQYILKLSNVG----GTKSIP-----ITVKVLDRPGPPEGPLKVTGVTAEKCY 24820 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W P+ G + +S Y ++ RE W V+ A Y KV+ L G Y+FRV AV Sbjct: 24821 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY-KVTKLLPGNEYIFRVMAV 24879 Query: 891 NANGVGKPSDTS-----EPVLVEARPGTKEISA------------GVDEQGNIYLGFDCQ 933 N G+G+P ++ P P T E+SA VD+ G G+ Sbjct: 24880 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-IL 24938 Query: 934 EMTDASQFTWCKSYEEISDDERFKI 958 E D W K ++ D R ++ Sbjct: 24939 EKRDKEGVRWTKCNKKTLTDLRLRV 24963 Score = 169 bits (429), Expect = 1e-41 Identities = 139/511 (27%), Positives = 223/511 (43%), Gaps = 34/511 (6%) Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +YIFRV+AVN G+ E ESD + + A P P + +SMT+ W P Sbjct: 27033 GNEYIFRVRAVNKYGIGE-PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIA 27091 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 GGS I GY+L+KR+ W +V + T V GLTE S Y++++ AVN AG G Sbjct: 27092 DGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPF 27151 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S+PSE +K A + PGP + + +S+ + W PVY G S V+GY V+ R+ + Sbjct: 27152 SEPSEFYKA-ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE 27210 Query: 857 GEWITVNQ--TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTK 914 EW TV+ Y+ VS+L+ G Y FRV AVN G G+P + +EPV + Sbjct: 27211 EEWTTVSTKGEVRTTEYV-VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 27269 Query: 915 EISAGVDEQGNIY--LGFDCQEM-----TDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 EI V + ++ G D Q + TW K + + D R+ IE S L Sbjct: 27270 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 27329 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSN-EIKN------------P 1014 + + D G Y +++ + G S + + L+ A ++K+ P Sbjct: 27330 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPP 27389 Query: 1015 TIPLKSELAYEIFDK--GRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 I S + + +K R W H S++ I D R+ + GI Sbjct: 27390 LIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI--DLSEKTPFFFRVLAENEIGI 27447 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 E ++ I D K + +I K + + + ++G Sbjct: 27448 GEPCETTEPVK-AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGE 27506 Query: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKW 1163 + H +++ CE+ +V+ K+++V ++ Sbjct: 27507 QTWSHAGISKTCEI----EVSQLKEQSVLEF 27533 Score = 169 bits (429), Expect = 1e-41 Identities = 160/636 (25%), Positives = 264/636 (41%), Gaps = 66/636 (10%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P + +P W +D + LKES++ + E + +LS + K+ G YT+ Sbjct: 27583 LELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV------ 27636 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 + D++ + G P P ++ + D VI++W P + Y ++ Sbjct: 27637 -ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 27695 Query: 421 RCEVGTNNW-VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD 479 + E NW + C+ K P L + Y FRVRA N G+S+P S VA Sbjct: 27696 KRETSQTNWKMVCSSVARTTFKVP--NLVKDAEYQFRVRAENRYGVSQPLVSSIIVA--- 27750 Query: 480 PLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK 539 + ++PGPP ++ + + L+W+ P G Sbjct: 27751 -------------------------KHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGG 27785 Query: 540 DPLMYF-IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSE 598 + F +EK S WQ+VN + + Y L+EG Y FRV + N GLS PS+ Sbjct: 27786 SEVTGFHVEKKERNSILWQKVNT-SPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSD 27844 Query: 599 ITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLW 656 + A P P + +R T + ++W+ P + ++GY ++ G W Sbjct: 27845 PSKFTLAVSPVDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIE-KRQGNERW 27900 Query: 657 EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPY 715 CN + ++ V GL+ G++Y FR+ A NAVG +S SQ S +I + P + Sbjct: 27901 VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEF 27960 Query: 716 GITLLNCDGHSMTLG--WKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILT 771 G DG + G ++ G P+ + ++ D E+ + E+ T L Sbjct: 27961 GPEYF--DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS-TSLF 28017 Query: 772 VDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 V T + + A N +G S + + PG + F + + Sbjct: 28018 VRDATRDHRGVYTVEAKNASG-------SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W AP+ G +P++ Y ++ RE W + A Y + L G Y FRV AV Sbjct: 28071 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSAV 28129 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNI 926 N GVG+P D S+PV+ + + T + G+ E NI Sbjct: 28130 NKFGVGRPLD-SDPVVAQIQ-YTVPDAPGIPEPSNI 28163 Score = 169 bits (427), Expect = 2e-41 Identities = 159/618 (25%), Positives = 253/618 (40%), Gaps = 50/618 (8%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK 441 AP P L D + V + W P S + GY ++ G++ W VK + Sbjct: 20964 APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITT--VKGLE 21021 Query: 442 YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V L EG Y F+V AVNSAG S P R S V + L L + + IA Sbjct: 21022 CVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAG 21080 Query: 502 DDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNA 561 D+++ + V G P ++W+ +G L QRVN Sbjct: 21081 DNIKVEIPVLGRPKPT-----------VTWK----KGDQILK-----------QTQRVNF 21114 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +T S + + + S + + + N G E ++ + IQ D+ P+ P + Sbjct: 21115 ETTATSTILNINECVRSDSGPYPLTARNIVG--EVGDVIT-IQVHDIPGPPTGP--IKFD 21169 Query: 622 RNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 + V WD P+++ + Y V+ + W I + LTTG + Sbjct: 21170 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLE 21228 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y FRVKA N G+ + ++ VP P + SMT+ W P GG Sbjct: 21229 YQFRVKAQNRYGVGPGITSACIV-ANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGG 21287 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPILGY+++++E + W V+ + I GLT+G YEF++ A N+AG +PS P Sbjct: 21288 SPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKP 21347 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 SE P PG L + ++ + W P Y+G ++ Y V+ R+ G W Sbjct: 21348 SEPMLALDPIDP-PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW 21403 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPVLVEARPGTKEISA 918 + N + VS L + Y FRV A NA G + PS+ S+ + +I Sbjct: 21404 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 21463 Query: 919 GVDEQGNIYL--GFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 V + + L G + D S W K +E+ + +I+ + L K+ Sbjct: 21464 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKD 21523 Query: 972 PDKEDLGTYSVSVSDTDG 989 + D G Y+++ ++ G Sbjct: 21524 STRRDSGAYTLTATNPGG 21541 Score = 168 bits (426), Expect = 3e-41 Identities = 145/581 (24%), Positives = 244/581 (41%), Gaps = 63/581 (10%) Query: 335 EGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDA 394 +G++ L + D GLY +++ + G++ + V D PG P++ D Sbjct: 14761 KGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDI 14813 Query: 395 NRDYVIVTWKPPNTTTESPVMGYFVDRCE--VGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 + V+ W+PP S ++ Y +++ + + W+ + ++ CKY VT L EG+ Sbjct: 14814 RKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCKYSVTKLIEGKE 14872 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y+FRVRA N G P VS + A DP G P Sbjct: 14873 YLFRVRAENRFGPGPPC-VSKPLVAKDPF------------------------GPPDAPD 14907 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +++ N +++ W P G L Y++EK V S W RVN ++ + + + V Sbjct: 14908 KPI---VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVN-KSLLNALKANV 14963 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 L+EG +YVFRV + N G + S + P A D + P P + + T++ ++W Sbjct: 14964 DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIELEW 15022 Query: 633 DRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + P +++GY+VD + GTN W C K I ++ V + G Y RV AVNA Sbjct: 15023 EPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAA 15082 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITL-LNCDGHSMTLGWK---VPKFSGGSPILGYY 746 G + V + P P + L ++ G + K +P G P+ Sbjct: 15083 GEGPPGETQPV-----TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 15137 Query: 747 LDKREVH-HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 K E K+ +++ +K ++ D L + + I A N G S+ Sbjct: 15138 WTKEEGELDKDRVVIDNVGTKSELIIKDALRKDH-GRYVITATNSCG-------SKFAAA 15189 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 PGP DL ++ W P G S ++G+ ++ ++ W +T Sbjct: 15190 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET 15249 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 + ++ L +G+ Y FRV A N G G P + P+L Sbjct: 15250 ERSK--CDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PIL 15287 Score = 167 bits (424), Expect = 5e-41 Identities = 156/610 (25%), Positives = 250/610 (40%), Gaps = 58/610 (9%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P L R +P W + D +LK+++ L+ + + D G Y L +R V Sbjct: 21088 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL--TARNIVG 21145 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + ++ D + G P P+ + + D+V +W PP P+ Y V+ + Sbjct: 21146 EVGDVITIQVHD--IPGPPTGPIKFD--EVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 21201 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + WV+ ++ Y T L G Y FRV+A N G+ P S + A P Sbjct: 21202 DSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPF--- 21256 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 +VPGPP + ++++ + +SW P G P++ Sbjct: 21257 ------------------------KVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILG 21292 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ WQ V ++ V + L +G +Y FRV++ N G S+PS+ + P+ Sbjct: 21293 YHVERKERNGILWQTV-SKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 21351 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNH 661 A D PG+ + T+ +V ++W +P++ + Y V+ W N Sbjct: 21352 LALDPI---DPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 21408 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPYGI--- 717 I N F V GLT Y FRV A NA G +S S+ SD I + + P + Sbjct: 21409 SNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFK 21468 Query: 718 -TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLT 776 T++ G + L V P + + D +E+ E+ + ++ D T Sbjct: 21469 DTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS-T 21525 Query: 777 EGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 + + A N G + F + P P P L EV V+ W P Sbjct: 21526 RRDSGAYTLTATNPGGFAK-----HIFNVKVLDRPGP-PEGPLAVTEVTSEKCVLSWFPP 21579 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 + G + + Y V RE W V + LKV+ L +G Y+FRV AVN GVG Sbjct: 21580 LDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTK-LKVTKLLKGNEYIFRVMAVNKYGVG 21638 Query: 897 KPSDTSEPVL 906 +P + SEPVL Sbjct: 21639 EPLE-SEPVL 21647 Score = 167 bits (424), Expect = 5e-41 Identities = 158/611 (25%), Positives = 256/611 (41%), Gaps = 64/611 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R +P W +D + LK++ + +LS HKDD G Y + + + G S Sbjct: 23256 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 23315 Query: 369 FLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTN 427 + D DP P P+ D + + + ++W PP T + Y V + + T Sbjct: 23316 EIVTLDKPDP-----PKGPVKFD--DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 23368 Query: 428 NWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQ 487 W A V VT L G Y FR+ A N G Q Sbjct: 23369 VW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYG----------------------Q 23405 Query: 488 AVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFI 546 + LE + +A Y + PGPP A+ IS++ +V+ W P G P++ Y + Sbjct: 23406 SFALESDPIVAQYP------YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 23459 Query: 547 EKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ 606 E+ S W +VN +T + ++ +L EG Y FRV + N G+ + S+ + A+ Sbjct: 23460 ERKERNSILWTKVN-KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 23518 Query: 607 DVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPI 664 D P P ++ RN + +QW +P ++ + GY V+ W + + Sbjct: 23519 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 23575 Query: 665 GYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVP----SHPYGITL 719 +F V GLT ++Y FRV A NA G +S+ S + I + + +P + T+ Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 23635 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL-TEG 778 + G + L + P + + +E+ E+ ++ K ++ D + +G Sbjct: 23636 VVNAGETFRL--EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 23693 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLVMLWKAPV 837 Y + A N+AG S+ F + PGP + V + W P+ Sbjct: 23694 GQYILR--ASNVAG-------SKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPL 23744 Query: 838 YSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G S +S Y V+ RE W V N LKV+ L +G YVFR+ AVN GVG+ Sbjct: 23745 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIMAVNKYGVGE 23803 Query: 898 PSDTSEPVLVE 908 P + S PVL++ Sbjct: 23804 PLE-SAPVLMK 23813 Score = 167 bits (423), Expect = 7e-41 Identities = 161/636 (25%), Positives = 268/636 (42%), Gaps = 74/636 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P+ L + R V + W P T + Y V++ ++ W++ N + + ++ Sbjct: 21360 PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 21416 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V+GL E +Y FRV A N+AG IS PS SDA+ D ++ +++ V ++ + + + Sbjct: 21417 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIK-VDVKFKDTVILKA 21475 Query: 502 DD---LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + LE D PPT + W + I+ + S Sbjct: 21476 GEAFRLEADVSGRPPPT-------------MEWSKDGKELEGTAKLEIK---IADFSTNL 21519 Query: 559 VNAQTAVR-SPRYAVFDLMEG--KSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 VN + R S Y + G ++F V +R G E Sbjct: 21520 VNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-------------------- 21559 Query: 616 GRVLASRNTKTSVVVQWDRPKHEEDL-LGYYV-----DCCVAGTNLWEPCNHKPIGYNRF 669 G + + T V+ W P + + +Y+ +A TN+ + + Sbjct: 21560 GPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV-----ASEVQVTKL 21614 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V L G +YIFRV AVN G+ E + V+ V P P + SM + Sbjct: 21615 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNP-YGPPDPPKNPEVTTITKDSMVV 21673 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W P GGS I+ Y +++R+ + W + N V GLTEG YEF+I A N Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 21733 Query: 790 LAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848 AGI PS S +K C+ T+ +PGP + + +S+ + W P+Y G S ++GY Sbjct: 21734 AAGISAPSPTSPFYKACD--TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYM 21791 Query: 849 VDFR--EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 V+ EED + +T A Y ++ L + + Y R+ A+N+ G+G+P+ Sbjct: 21792 VEIALPEEDEWQIVTPPAGLKATSY-TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 21850 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQ-------EMTDASQFTWCKSYEEISDDERFKIE 959 E R EI D + + + C + A + W + + E D + IE Sbjct: 21851 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 21908 Query: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ L + N ++ D G Y ++V ++ G S+FV Sbjct: 21909 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFV 21944 Score = 167 bits (422), Expect = 9e-41 Identities = 157/616 (25%), Positives = 246/616 (39%), Gaps = 58/616 (9%) Query: 309 RVQPRAEWYR---DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSD 365 R P+ W + D+V+ K ++ + A L + +DD G Y+L +V+ G + Sbjct: 18633 RPAPKVTWRKVGIDNVVRKG----QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG--E 18686 Query: 366 HSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVG 425 + F+ VR D PG DL+ D + V+W PP S V Y V++ E Sbjct: 18687 KAVFVNVRVLD-----TPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 18741 Query: 426 TNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 W VK + VT L G Y FRV AVN G P+ V V A DPL Sbjct: 18742 RKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL---- 18796 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 P PP + +E+++N L+W PP G + + Sbjct: 18797 -----------------------SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 18833 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQA 605 I R + V+ V L EGK Y FRV + N G+S P E +A Sbjct: 18834 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 18893 Query: 606 QDVTVVPS--APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKP 663 ++ + P P ++ K + H D V ++L HK Sbjct: 18894 KEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL---AVHKA 18950 Query: 664 IGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCD 723 + ++ +T + + + A N+ G ++Q+ V+ V A P P+ I+ + D Sbjct: 18951 DSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVV-VMDAPGPPQPPFDIS--DID 19005 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + +L W +P GGS I Y ++K +V +W +S +K T V L G Y F Sbjct: 19006 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIF 19064 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSP 843 ++ A N GI EP + + P + +V + + W P G SP Sbjct: 19065 RVRAENRFGISEPLTSPK--MVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSP 19122 Query: 844 VSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE 903 + GY ++ +E ++ W+ N T + + L +G Y FR+ A+N G PS +E Sbjct: 19123 IIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTE 19182 Query: 904 PVLVEA---RPGTKEI 916 V PG E+ Sbjct: 19183 YVTARMPVDPPGKPEV 19198 Score = 166 bits (420), Expect = 2e-40 Identities = 155/611 (25%), Positives = 243/611 (39%), Gaps = 63/611 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + D L + ++ + SLS + D G Y L+ + G + + Sbjct: 22573 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + A + + WKPP S ++ Y V+R E W Sbjct: 22633 VLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDIINYIVERRETSRLVWTV 22686 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 DA V+ VT L EG Y FR+ AVN G+ P S+ V A +P Sbjct: 22687 V-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEPVVAKNPF---------- 22734 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWE-PPTPRGKDPLMYFIEKSV 550 VP P + ++++ +++ WE P + G + L Y +EK Sbjct: 22735 -----------------VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRD 22777 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 W R + + + R V L+E Y FRV + N GLSEPS ++ +A D Sbjct: 22778 KEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 22836 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P P T++SV + W +P ++ ++ GY V+ C W C P G N+ Sbjct: 22837 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCT-PPTGINK 22895 Query: 669 --FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHS 726 V L +Y FR+ A+N G+ E++ I V+ L P + L Sbjct: 22896 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKI---- 22951 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 + +GGS L + R W +V+ I+ V S + Sbjct: 22952 ------INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV----TSSFTSLVLD 23001 Query: 787 AVNLAGIG------EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 VN G E S ++ + P P +L E+ S+ + W+ P+ G Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDG 23061 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 S + Y V+ RE + V N + K+ LQ+G +Y FRV A N G+G P+ Sbjct: 23062 GSKIKNYIVEKREATRKSYAAVVTNCHKNSW-KIDQLQEGCSYYFRVTAENEYGIGLPAQ 23120 Query: 901 TSEPVLVEARP 911 T++P+ V P Sbjct: 23121 TADPIKVAEVP 23131 Score = 165 bits (418), Expect = 3e-40 Identities = 154/563 (27%), Positives = 231/563 (41%), Gaps = 60/563 (10%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ AP P + D + + W PP S V GY V+ E G W + D Sbjct: 16417 DPI---APPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 16473 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 V+ K VTGL EG Y FRVRAVN AGI P V+D + D L Sbjct: 16474 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-------------- 16519 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 DL+ DA V VHA + R +S +PP + + + + + Sbjct: 16520 ----VSPDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPT-----VTWNMNERTLP--- 16566 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 Q +T S + + V+ +L+ N G + + I DV VP Sbjct: 16567 -QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIV------DVLDVPGPV 16619 Query: 616 GRVLASRN-TKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672 G + N T S + W P+ + + Y ++ + W P + N V Sbjct: 16620 GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQ 16678 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWK 732 GL G+ Y FR+ A N++GM + S+ + ++ +TVP P + + +++TL W Sbjct: 16679 GLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN 16738 Query: 733 VPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792 PK+ GGS I+ Y L+ R + + +H+V + TV GL EG YE++++AVN+ G Sbjct: 16739 PPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 16798 Query: 793 IGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPV----YSGS-SPVSGY 847 G+PS ++ C+ P P L F RD + + +A YSG P + Sbjct: 16799 QGKPSFCTKPITCKDELAP---PTLHLDF---RDKLTIRVGEAFALTGRYSGKPKPKVSW 16852 Query: 848 FVDFRE--EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 F D + ED I T A +K GK V V N G + Sbjct: 16853 FKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV-----VVENSTGSRKGFCQVN 16907 Query: 906 LVEARPGTKEISAGVDEQGNIYL 928 +V+ RPG DE Y+ Sbjct: 16908 VVD-RPGPPVGPVSFDEVTKDYM 16929 Score = 162 bits (410), Expect = 2e-39 Identities = 182/806 (22%), Positives = 327/806 (40%), Gaps = 96/806 (11%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP I ++ T + +L + G P P ++WY+ G + Q+ KY++ S+ H Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR---KYKMSSDGRTH 30588 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 TL + + +D Y+ +ATN G+V T++ ++++ P Sbjct: 30589 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA----------------------TP 30626 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H EK+ + G T+ L + P P W+ LL+ S+ + Sbjct: 30627 QFHPGYPLKEKY---YGAVGSTLRLHVMYIGRP-----VPAMTWFHGQKLLQNSENITIE 30678 Query: 333 FGEGQASLSFSHLH-KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 E L ++ K G Y +++ + G D + ++D TG P+ ++ Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG----PIVIEA 30734 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 N +++WKPP S + Y V++CE Q + + + + L E Sbjct: 30735 LLKNS--AVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 30792 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 Y FRV A N+ GIS P VS V P + P Sbjct: 30793 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------P 30825 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 G P + ++++ V++W+PP G + Y++EK W V + +R + Sbjct: 30826 GAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE-IRETVF 30884 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-DVTVVPSAPGRVLASRNTK--TS 627 +V +L+EG Y FRV N G SE SEI+ PI + DV + L + N + ++ Sbjct: 30885 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 30944 Query: 628 VVVQWDRPKHEEDLLGYYVDCC-VAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 + H + ++ +Y + L GY++ ++ +T + +++V+A Sbjct: 30945 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRA 31004 Query: 687 VNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC-DGHSMTLGWKVPKFSGGSPILGY 745 N G S + S ++V A + +P G+ ++ G +++ K+P P++ + Sbjct: 31005 TNQGG-SVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITW 31061 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + + + ++V + S +++ +G+ + + A N GI + + Sbjct: 31062 QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT-------V 31114 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 E P P + +V S+ + W P G S ++ Y V+ A W+ V Q Sbjct: 31115 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ- 31173 Query: 866 TTANRYLKVSDLQQGKT-YVFRVRAVNANGVGKPSDTSEPVLV-EARPGTKEISAGVDEQ 923 RY ++ GKT Y FRV A N G+ KPS+ SEP + E + VDE Sbjct: 31174 ARETRYTVINLF--GKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDET 31231 Query: 924 GNIYLGFDCQEMTDASQFTWCKSYEE 949 + MT AS + + YE+ Sbjct: 31232 REV-------SMTKASHSSTKELYEK 31250 Score = 161 bits (408), Expect = 4e-39 Identities = 155/638 (24%), Positives = 255/638 (39%), Gaps = 72/638 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P +L D + +V + W+ P+ SP + Y V+R G+++W + + +K Y Sbjct: 18101 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHY 18160 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD----PLDLRRLQAVHLEGEKEIA 498 V E + Y FRV+ N G S + + V D LDL+ + ++ I Sbjct: 18161 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIR 18220 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + +A V G P + ++W +K R Sbjct: 18221 L-------EAGVRGKP-----------FPEVAWTK-------------DKDATDLTRSPR 18249 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V T S ++++ + V + N G A V PG V Sbjct: 18250 VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG---------SFVAYATVNVLDKPGPV 18300 Query: 619 LASRNTKTSVV------VQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 RN K V V WD P+ + ++ Y ++ C +W + + V Sbjct: 18301 ---RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTV 18357 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 L G +YIFRV+A N +G ++ VI + P P + MT+ Sbjct: 18358 TR-LIEGNEYIFRVRAENKIGTGPPTESKPVI-AKTKYDKPGRPDPPEVTKVSKEEMTVV 18415 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W P++ GG I GY+L+K+E H W VN S + V L Y+F++ A N Sbjct: 18416 WNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENE 18475 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 GIGEPS PS + P PGP + + S+ + W PVY G +P+ GY V+ Sbjct: 18476 IGIGEPSLPSRPVVAKDPIEP-PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVE 18534 Query: 851 FREEDAGE-----WITVNQTT-TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 R + A W N + V+ L + + Y FRV A N G+G+P++ E Sbjct: 18535 MRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEA 18594 Query: 905 VLVE--ARPGTKEISAGVDEQGNIYLG-----FDCQEMTDASQFTWCKSYEEISDDERFK 957 + + P ++ A + + + G F A + TW K + + + + Sbjct: 18595 IKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQ 18653 Query: 958 IETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 ++ V + L + N ++D G YS+++ + G + FV Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 18691 Score = 161 bits (407), Expect = 5e-39 Identities = 157/614 (25%), Positives = 257/614 (41%), Gaps = 62/614 (10%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R P W++D+V LK++ E + L+ ++D G Y +++ + G + Sbjct: 22170 PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + V D G P P+ + + D + ++W PP S + Y V++ + Sbjct: 22230 IETLNVIVLDKP----GPPTGPVKMD--EVTADSITLSWGPPKYDGGSSINNYIVEKRDT 22283 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 T W Q A V L G Y FR+ A N G Sbjct: 22284 STTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAENRYG-------------------- 22322 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLM 543 ++ +L E +A Y +VPGPP + SR+ + + W EP + G + Sbjct: 22323 --KSTYLNSEPTVAQYP------FKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 22374 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ S W ++N +T + ++ L EG Y FRV + N G+ +PS+++ Sbjct: 22375 YHLERKERNSILWVKLN-KTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY 22433 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D P P ++ +RN SV +QW +P ++ + GY V+ W + Sbjct: 22434 VARDPCDPPGRPEAIIVTRN---SVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 22490 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGM-SENSQESDVIKVQAALTVP----SHPYG 716 I F V GL +Y FRV A NA G+ SE S+ + I + + P Y Sbjct: 22491 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYK 22550 Query: 717 ITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774 T++ G S +KV G PI + + +E+ + E+ S+ ++ D Sbjct: 22551 DTIVVHAGES----FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDA 22606 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 + S + + A N+AG + S + P P P + V + WK Sbjct: 22607 VRVDS-GNYILKAKNVAG-----ERSVTVNVKVLDRPGP-PEGPVVISGVTAEKCTLAWK 22659 Query: 835 APVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG 894 P+ G S + Y V+ RE W TV KV+ L +G Y FR+ AVN G Sbjct: 22660 PPLQDGGSDIINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 22718 Query: 895 VGKPSDTSEPVLVE 908 VG+P + SEPV+ + Sbjct: 22719 VGEPLE-SEPVVAK 22731 Score = 160 bits (406), Expect = 6e-39 Identities = 164/646 (25%), Positives = 251/646 (38%), Gaps = 84/646 (13%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 EGE +++ P P W++D +K S M A L + D Sbjct: 14400 EGEKLSIPVPFRAVP-----VPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G+YT+ + ++ G + S + V G PG D++ D + +TW+PP Sbjct: 14455 GIYTITLENKLGSATASI-------NVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDG 14507 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 +P++ Y ++R E G ++ K+ + V L Y FRV+AVN G Sbjct: 14508 GTPILHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIE 14566 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 + + V A DP Q P PP V + + ++ Sbjct: 14567 LKNPVIAQDP---------------------------KQPPDPPVDVEVHNPTAEAMTIT 14599 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W+PP G +M Y IEK G W+R N + V Y L EGK Y FRV + N Sbjct: 14600 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCN-EHLVPILTYTAKGLEEGKEYQFRVRAEN 14658 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVL------------ASRNTKTSVVVQWDR--- 634 G+SEPS T P +A D P R AS + + W + Sbjct: 14659 AAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDEN 14718 Query: 635 ---PKHEEDLLGYYVDCCVAGTNLWEP----------CNHKPIGYNRFVVHGLTTGEQYI 681 P+ + V EP ++ G ++ V + + Sbjct: 14719 VIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGL 14778 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSP 741 + +K N G+++ V L P P + S+ W+ P GGS Sbjct: 14779 YMIKVENDHGIAKAPCTVSV------LDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSE 14832 Query: 742 ILGYYLDKRE--VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 I+ Y L+K++ W V S+ + +V L EG Y F++ A N G G P Sbjct: 14833 IINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVS 14891 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCE-VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + P+ A D E V S+++ W P +G SP+ GY+++ RE ++ Sbjct: 14892 KPLVAKDPFGPPD---APDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTH 14947 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 W VN++ V L +G TYVFRV A NA G GK S S+P Sbjct: 14948 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 14993 Score = 158 bits (399), Expect = 4e-38 Identities = 128/444 (28%), Positives = 198/444 (44%), Gaps = 35/444 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 P P + +I+++ V L+WEPP G PL Y +EK V +W +V V Sbjct: 13488 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV--MDFVTDLE 13545 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V DL++GK Y+F+V + N+ G EP+ + P+ VP P V T S+ Sbjct: 13546 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 13605 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + WD PK++ + GY V+ C G++ W C +P+ + V GL G+ Y +RVKA+ Sbjct: 13606 LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPVAETKMEVTGLEEGKWYAYRVKAL 13664 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV--PKFSGGSPILGY 745 N G S+ S+ ++ I+ P + LL G ++ G K+ P G P Sbjct: 13665 NRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL--AGLTVKAGTKIELPATVTGKPEPKI 13722 Query: 746 YLDKREVHHKNWHE--VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 K ++ K + + P K T+ VD + I AVN+ G Sbjct: 13723 TWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGTYIIEAVNVCGRATA------- 13774 Query: 804 KCEAWTMPEPGP--AYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWIT 861 E + +PGP A+D+T +V + S ++ W P G S ++ Y V+ R D+ W Sbjct: 13775 VVEVNVLDKPGPPAAFDIT--DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 13832 Query: 862 VNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVD 921 ++ T + K + L K Y+FRV A N GVG+P V+A P T + D Sbjct: 13833 LSSTVKDTNF-KATKLIPNKEYIFRVAAENMYGVGEP--------VQASPITAKYQ--FD 13881 Query: 922 EQGNIYLGFDCQEMTDASQFTWCK 945 G DA TWC+ Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCE 13905 Score = 157 bits (397), Expect = 7e-38 Identities = 168/638 (26%), Positives = 259/638 (40%), Gaps = 70/638 (10%) Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V+ A+P P P + D ++ + W+ P S V+GY V+ GT W Sbjct: 24207 VKAAEP-----PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSI 24261 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 ++ K+C VTGL G+ Y FRV+A N G S P + V A D L ++ L Sbjct: 24262 VAES--KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD---LTIQPSLKL 24316 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVV 551 +DL+ + V G P +SW + +PL Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPN-----------ISWV----KDGEPLK-------- 24353 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF---RVLSANRHGLSEPSEITSPIQAQDV 608 RVN + S V + EG F V + N G + +E S I V Sbjct: 24354 ---QTTRVNVEETATS---TVLHIKEGNKDDFGKYTVTATNSAGTA--TENLSVI----V 24401 Query: 609 TVVPSAP-GRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIG 665 P P G V + VV+ W+ P + + Y V+ T W + + Sbjct: 24402 LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS-ATVA 24460 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 + L TG +Y FR+ A N G S VI VQ P P + + Sbjct: 24461 RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI-VQYPFKEPGPPGTPFVTSISKD 24519 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 M + W P GG+ I+GY+L+++E + W ++N +P + T GL EG YEFK+ Sbjct: 24520 QMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKV 24579 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 +A N+ GIG+PS SE F P P + + ++ + WK P Y G S ++ Sbjct: 24580 SAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV----ITRNNVTLKWKKPAYDGGSKIT 24635 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEP 904 GY V+ ++ G W+ + T VS L + + Y FRV A NA G +PSD+S Sbjct: 24636 GYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSG- 24694 Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEM---------TDASQFTWCKSYEEISDD-E 954 + AR +A +D + + E W K +E+ + Sbjct: 24695 -AITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAA 24753 Query: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 R +I++ + L +K+ + D G Y + +S+ G S Sbjct: 24754 RMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 24791 Score = 151 bits (382), Expect = 4e-36 Identities = 175/732 (23%), Positives = 295/732 (40%), Gaps = 58/732 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP +I + V+ WEPP G ++ Y +EK + + + +R + Sbjct: 14802 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 14861 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y+V L+EGK Y+FRV + NR G P ++ P+ A+D P AP + + T S++ Sbjct: 14862 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 14920 Query: 630 VQWDRPK-HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 V+W+ PK + +LGY+++ + W N + + V GL G Y+FRV A N Sbjct: 14921 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 14980 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 A G + S SD ++ P P + + ++ L W+ P F+GG I+GY++D Sbjct: 14981 AAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVD 15039 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 K+ V W K TV + EG+ Y+ +++AVN AG G P + E Sbjct: 15040 KQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-- 15097 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWK-----APVYSGSSPVSGYFVDFREEDAGEWITVN 863 P+ PA +L V+ +M K A V P + + E D + N Sbjct: 15098 --PQEPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN 15154 Query: 864 QTTTANRYLKVSDLQQGKTYV----------FRVRAVNANGVGKPSDTSEPVLVEARPGT 913 T + +K + + YV F V V P +PV+ + Sbjct: 15155 VGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL 15214 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPD 973 S D+ G+ GF E DA TW + E ER K + G L+ + Sbjct: 15215 LNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIE----TERSKCDITG-----LLEGQE 15264 Query: 974 KEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVR 1033 + + V + G P E+ ++A+ + + PT P L Y K + Sbjct: 15265 YK----FRVIAKNKFGCG-----PPVEIGPILAV-DPLGPPTSP--ERLTYTERTKSTIT 15312 Query: 1034 F-WLQAEHLSPDASYRFIINDREVSDSEIHRIK---CDKATGIIEMVMDRFSIENEGTYT 1089 W + +II R + R+ C + ++E + + E Sbjct: 15313 LDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAV 15372 Query: 1090 VQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLV 1149 +I + + ++V+ D ++ R + ++ + E +H + + + Sbjct: 15373 NEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA---GEPVH--IPADVTGLPM 15427 Query: 1150 CKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQD 1209 K+ +K ETV + D L T+ + EL IPK ++D G Y T + G Sbjct: 15428 PKIEWSKNETVIE-KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSV 15486 Query: 1210 VSILEIAGKVYD 1221 + + +VYD Sbjct: 15487 FRNVHV--EVYD 15496 Score = 151 bits (382), Expect = 4e-36 Identities = 151/584 (25%), Positives = 239/584 (40%), Gaps = 82/584 (14%) Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPP 406 + D G Y + + G +A + V D PG +DL+ NR ++ W P Sbjct: 15168 RKDHGRYVITATNSCGSKFAAARVEVFDV-------PGPVLDLKPVVTNRKMCLLNWSDP 15220 Query: 407 NTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGIS 466 S + G+ ++R + + W Q + C +TGL EG+ Y FRV A N G Sbjct: 15221 EDDGGSEITGFIIERKDAKMHTWRQPIETERSKC--DITGLLEGQEYKFRVIAKNKFGCG 15278 Query: 467 RPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG---VHASEIS 523 P + + A+DPL GPPT + +E + Sbjct: 15279 PPVEIG-PILAVDPL------------------------------GPPTSPERLTYTERT 15307 Query: 524 RNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYV 582 ++ + L W+ P G P+ Y IEK ++RVN + + + V +L E + Y Sbjct: 15308 KSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLC-PTTSFLVENLDEHQMYE 15366 Query: 583 FRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH-EEDL 641 FRV + N G SEPS + + QD V P+ R+ +T + V+ P H D+ Sbjct: 15367 FRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDT---IKVKAGEPVHIPADV 15422 Query: 642 LGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------------QYIFRVKAV 687 G + N E KP + ++ E + + V A Sbjct: 15423 TGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 15480 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYL 747 N +G + +V PS P + + + S L W P +GGS I Y + Sbjct: 15481 NRLGSVFRNVHVEV------YDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 15534 Query: 748 DKREVHHK--NWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 DKR+ K W EV ++ + + L YEF++ AVN GI + + Sbjct: 15535 DKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 15593 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 + + +P P P + + LV W P+ +G SP++GY+++ REE + W V++ Sbjct: 15594 DPYRLPGP-PGKPKVLARTKGSMLVS-WTPPLDNGGSPITGYWLEKREEGSPYWSRVSRA 15651 Query: 866 TTANRYLK-----VSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 LK V L +G Y FR A+NA G+G PS+ S+P Sbjct: 15652 PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 15695 Score = 150 bits (379), Expect = 9e-36 Identities = 109/444 (24%), Positives = 202/444 (45%), Gaps = 39/444 (8%) Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 T + + + +G ++++ N+HG +E I + + V PG V Sbjct: 13047 TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF-----INLKVIDV----PGPVRNLE 13097 Query: 623 NTKT---SVVVQWDRPKHE--EDLLGYYVD-------CCVAGTNLWEPCNHKPIGYNRFV 670 T+T V + W+ P + ++GY V+ V T+ E C F Sbjct: 13098 VTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE--------FT 13149 Query: 671 VHGLTTGE-QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V GL G +Y+FRV A N VG E + + ++ ++ VP P +T+ + + ++L Sbjct: 13150 VTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSL 13209 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W+ P++ GG+ I Y ++ R+ W + ++ TV + EG Y F++ A N Sbjct: 13210 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQN 13269 Query: 790 LAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849 G+G+PS + K A + P P +LT + +S+ + W+ P+ G SP+ GY + Sbjct: 13270 RIGVGKPSAATPFVKV-ADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 13328 Query: 850 DFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA 909 + EE WI N KV+ L++G Y++RV A N GV PS+ P+ + Sbjct: 13329 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 13388 Query: 910 R--PGTKEISAGVDEQGNIYLGFDCQEMTDASQF-----TWCKSYEEISDDERFKIETVG 962 T ++SA D + + + ++ + TWC + + +R K++T+ Sbjct: 13389 AFVEPTMDLSAFKDGL-EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 13447 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSD 986 +++L + ++ D G Y++ + + Sbjct: 13448 AYAELVISPSERSDKGIYTLKLEN 13471 Score = 150 bits (378), Expect = 1e-35 Identities = 138/520 (26%), Positives = 208/520 (40%), Gaps = 88/520 (16%) Query: 375 ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD--RCEVGTNNWVQC 432 +DPL P P L+ + ++ + W PP + + GY E + W + Sbjct: 18793 SDPL--SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEY 18850 Query: 433 NDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAA----LDPLDLRRLQ- 487 + VK VTGL EG+ Y FRV A N+ G+S P A L P L Q Sbjct: 18851 S--VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI 18908 Query: 488 -------------------------------------AVHLEGEKEIAIYQDDLEGDA-- 508 AVH I I +D D+ Sbjct: 18909 TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 18968 Query: 509 ---------------------QVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YF 545 PGPP S+I + LSW P G + Y Sbjct: 18969 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYI 19028 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP-IQ 604 +EK V G W V A +V V L+ G+ Y+FRV + NR G+SEP +TSP + Sbjct: 19029 VEKCDVSRGDW--VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMV 19084 Query: 605 AQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHK 662 AQ VPS P ++ K + V WDRP + ++GY ++ + LW N Sbjct: 19085 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 19144 Query: 663 PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC 722 + + GL G +Y FR+ A+N G S S+ ++ + + + P P +++ Sbjct: 19145 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKP---EVIDV 19201 Query: 723 DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTVDGLTEGSL 780 +++L W PK GGS I+GY+++ ++ W N++P + T GL E + Sbjct: 19202 TKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQ 19261 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLT 820 Y+F+ A I PS+PS+ A +P P DL+ Sbjct: 19262 YQFRAIARTAVNISPPSEPSDPVTILAENVP---PRIDLS 19298 Score = 149 bits (376), Expect = 2e-35 Identities = 199/866 (22%), Positives = 327/866 (37%), Gaps = 118/866 (13%) Query: 150 ISRAPEIL--VRLRSHTVWER-MSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 I APEI V LR+ + + V++ +G P P V W KD + A +Y IE Sbjct: 27265 ILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA---RYSIE 27321 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 + L I + +DT Y N +G P Sbjct: 27322 NTDSSSLLTIPQVTRNDTGKYILTIENG----------------------------VGEP 27353 Query: 267 LSSMIPYTHFDVQFL-EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKE 325 SS + D +K V G TVTL + P + P + + + Sbjct: 27354 KSSTVSVKVLDTPAACQKLQVKHVSRG-TVTL---LWDPPLIDGGSPIINYVIEKRDATK 27409 Query: 326 SKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGA 385 W+ + +S SF + ++ + R+++ + +P+ A Sbjct: 27410 RTWSVV--SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEP---CETTEPVKAAEVPA 27464 Query: 386 PM-DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPV 444 P+ DL D+ + VI++W P+ S + Y V+R G W + K C+ V Sbjct: 27465 PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGIS--KTCEIEV 27522 Query: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504 + L E FRV A N G+S P + P+ ++ L I + DL Sbjct: 27523 SQLKEQSVLEFRVFAKNEKGLSDP-------VTIGPITVKEL----------IITPEVDL 27565 Query: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTA 564 + +PG V I N + E P P + +++ + Sbjct: 27566 ---SDIPGAQVTVR---IGHN---VHLELPYKGKPKPSISWLKDGL-------------P 27603 Query: 565 VRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ--AQDVTVV----PSAP-GR 617 ++ + F E K + + HG + + + A +TV+ PS P G Sbjct: 27604 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 27663 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHK----PIGYNRFVVHG 673 + SV++ WD P ED G + C N K + F V Sbjct: 27664 IRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPN 27720 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 L +Y FRV+A N G+S+ S +I + +P P + N M+L W Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQ-PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDA 27779 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 P + GGS + G++++K+E + W +VN+SP GL EG Y+F++ A N AG+ Sbjct: 27780 PVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 27839 Query: 794 GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE 853 PSDPS+ + P P Y +V ++ + W P+ G S + GY ++ R+ Sbjct: 27840 SSPSDPSKFTLAVSPVDPPGTPDY----IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ 27895 Query: 854 EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP----------SDTSE 903 + W+ N T + V+ L G Y FR+ A NA G P D + Sbjct: 27896 GNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV 27954 Query: 904 PVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGD 963 P +VE G + + + G + + TW K EI +I V Sbjct: 27955 PPIVEF--GPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG 28012 Query: 964 HSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L++++ ++ G Y+V + G Sbjct: 28013 STSLFVRDATRDHRGVYTVEAKNASG 28038 Score = 149 bits (376), Expect = 2e-35 Identities = 139/518 (26%), Positives = 220/518 (42%), Gaps = 56/518 (10%) Query: 511 PGPPTG-VHASEISRNYVVLSWEPPTPRG-KDPLMYFIEKSVVGSGSWQRVNAQTAVRSP 568 P P G + +I V +SW PP G D L Y +E+ V +W ++++ VR Sbjct: 30228 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR--VRGT 30285 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ---DVTVVPSAPGRVLASRNTK 625 V L E Y FRV + N+ G+S+P + P+ + + PS P VL TK Sbjct: 30286 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV--TK 30343 Query: 626 TSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFR 683 +SV + W RPK + + GYY++ T+ W N I + V GL +Y FR Sbjct: 30344 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 30403 Query: 684 VKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPIL 743 + A N VG+SE S S+ + + PS P + +L+ S+TL W+ P+ GG IL Sbjct: 30404 IIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEIL 30463 Query: 744 GYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 GY+++ R+ W + N K T+ GL E + YEF++ A N G+ P + Sbjct: 30464 GYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSI 30523 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 K + + PG E++D + + G + + R +W Sbjct: 30524 KTKLTSGEAPGIRK-----EMKDVTTKL--------GEAAQLSCQIVGRPLPDIKWYRFG 30570 Query: 864 QTTTANRYLKVSDLQQGKTYVFRV-----------RAVNANGVGKPSDTSEPVLVEARP- 911 + +R K+S G+T+ V + N VG+ +TS +L++A P Sbjct: 30571 KELIQSRKYKMS--SDGRTHTLTVMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQ 30627 Query: 912 -----GTKEISAGVD----EQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVG 962 KE G +Y+G M TW + + + E IE Sbjct: 30628 FHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAM------TWFHGQKLLQNSENITIENTE 30681 Query: 963 DHSKLYLKNPD-KEDLGTYSVSVSDTDGVSSSFVLDPE 999 ++ L +KN K G Y V +S+ G + +LD E Sbjct: 30682 HYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA-ILDVE 30718 Score = 147 bits (371), Expect = 7e-35 Identities = 164/689 (23%), Positives = 272/689 (39%), Gaps = 81/689 (11%) Query: 250 RGDEEPFRSVGLP-----IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 +G +P R +G+P I + S +P+ F+V+ E+ + +G Sbjct: 25374 KGRSDP-RQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKG------------ 25420 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 R Q W +D LKE+ + + SLS K+D G Y L + + G Sbjct: 25421 ----RPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 25476 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + V D PG P ++ + + D + ++W PP + Y V++ E Sbjct: 25477 TVPITIIVLDR-------PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKET 25529 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + W + A V + L G Y FRV A N G S S S VA Sbjct: 25530 TSTTWHIVSQA-VARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA-------- 25580 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 E PGPP +++ ++++W+ P G ++ Sbjct: 25581 --------------------EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIG 25620 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E S W + N + + + V L EG Y +RV + N G+ + S+ P+ Sbjct: 25621 YHLEYKERSSILWSKAN-KILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 25679 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D PG+ + T+ SV ++W +P ++ + GY V+ W CN+ Sbjct: 25680 PARDPC---DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 25736 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAV-GMSENSQESDVIKVQAALTVPSHPYGITLL 720 I F V LT ++Y FRV A NA +SE S+ + I V+ + P + Sbjct: 25737 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFR 25796 Query: 721 NCDGHSMTLGWKVPKFSGGS--PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 + K+ G P++ + D E+ + E+ S+ + T+LTV Sbjct: 25797 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNH-TLLTVKDCIRR 25855 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 ++ + N+AG S C+ P P PA L + + W P Sbjct: 25856 DTGQYVLTLKNVAG-----TRSVAVNCKVLDKPGP-PAGPLEINGLTAEKCSLSWGRPQE 25909 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G + + Y V+ RE W T+ + KV+ L +G Y+FRV VN GVG+P Sbjct: 25910 DGGADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 25968 Query: 899 SDT-----SEPVLVEARPGTKEISAGVDE 922 ++ +P V + P + EI++ E Sbjct: 25969 LESVAIKALDPFTVPSPPTSLEITSVTKE 25997 Score = 144 bits (364), Expect = 5e-34 Identities = 163/681 (23%), Positives = 264/681 (38%), Gaps = 79/681 (11%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P+ RD V LK + +++ D G Y + + G + + Sbjct: 26506 PKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV 26565 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + D + V + W+PP S V Y + + E T W + Sbjct: 26566 VLDRP----GPPTGPVVIS--DITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 26619 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 + A V V L G Y FR++A N GIS D +D + Sbjct: 26620 VS-ATVARTMMKVMKLTTGEEYQFRIKAENRFGIS------------DHIDSACVT---- 26662 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550 ++ PGPP+ + ++R + + W P G ++ Y +E Sbjct: 26663 ------------VKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD 26710 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 S WQ+ N + +R+ + V + G Y FRV + N G+ +PS + P+ A D Sbjct: 26711 RNSILWQKAN-KLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC- 26768 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P V + +K SV + W +P + + GY V+ W + + + Sbjct: 26769 --EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 26826 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY-GITLLNCDGHSM 727 F++ GLT QY FRV A NAVG N S+V+ + P + L + Sbjct: 26827 FIISGLTQNSQYEFRVFARNAVGSISNP--SEVVGPITCIDSYGGPVIDLPLEYTEVVKY 26884 Query: 728 TLGWKVPKFSGGS----PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG--LTEGSLY 781 G V +G S P + +Y D +E+ V ++ +IL D L G Y Sbjct: 26885 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-Y 26943 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 E K+ N G S + + P P P + F V + +LW+ P G Sbjct: 26944 ELKLR--NAMG-----SASATIRVQILDKPGP-PGGPIEFKTVTAEKITLLWRPPADDGG 26995 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 + ++ Y V+ RE W V++ + + + +G Y+FRVRAVN G+G+P ++ Sbjct: 26996 AKITHYIVEKRETSRVVWSMVSEHLE-ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 27054 Query: 902 SEPVLVEA-----RPGTKEI------------SAGVDEQGNIYLGFDCQEMTDASQFTWC 944 V A PG E+ S + + G+ G+ E D W Sbjct: 27055 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY-FLEKRDKKSLGWF 27113 Query: 945 KSYEEISDDERFKIETVGDHS 965 K +E D R K+ + ++S Sbjct: 27114 KVLKETIRDTRQKVTGLTENS 27134 Score = 141 bits (355), Expect = 5e-33 Identities = 122/473 (25%), Positives = 210/473 (44%), Gaps = 49/473 (10%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+ ++ L WEPP G + Y I+K ++ V+++ + S Sbjct: 24116 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTS-- 24173 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V +L EG Y FRV++ N G+ P E ++A + PS PG+V + ++TS Sbjct: 24174 FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP---PSPPGKVTLTDVSQTSAS 24230 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ GT W + VV GL++G++Y FRVKA Sbjct: 24231 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC--NAVVTGLSSGQEYQFRVKAY 24288 Query: 688 NAVGMSEN-----SQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 N G S+ + + +Q +L +P + Y I G + + ++P P Sbjct: 24289 NEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQA----GEDLKI--EIPVIGRPRPN 24342 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 + + D + V + + T+L + + ++ + A N AG +E+ Sbjct: 24343 ISWVKDGEPLKQTTRVNVEETATS-TVLHIKEGNKDDFGKYTVTATNSAGTA-----TEN 24396 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P P P + F EV +V+ W+ P Y+G +S Y V+ R+ W V Sbjct: 24397 LSVIVLEKPGP-PVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMV 24455 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE------ARPGTKEI 916 + T A +K++ L+ G Y FR+ A N G P D S+ V+V+ PGT + Sbjct: 24456 S-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIVQYPFKEPGPPGTPFV 24513 Query: 917 SA------------GVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFK 957 ++ V++ G +G+ E + + W K + D +FK Sbjct: 24514 TSISKDQMLVQWHEPVNDGGTKIIGYHL-EQKEKNSILWVKLNKTPIQDTKFK 24565 Score = 140 bits (353), Expect = 9e-33 Identities = 116/421 (27%), Positives = 187/421 (44%), Gaps = 32/421 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGP + ++I+++ V L W+ P G + Y +EK S+ A T Sbjct: 20868 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS--TATTKCHKCT 20925 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y V L EG Y FRV++ N +G+ EP+E T P++A + PS P + TK++V Sbjct: 20926 YKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLNIMDITKSTVS 20982 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W +PKH+ + GY ++ G++ W + + VV LT GE+Y F+V AV Sbjct: 20983 LAWPKPKHDGGSKITGYVIEAQRKGSDQW--THITTVKGLECVVRNLTEGEEYTFQVMAV 21040 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI---TLLNCDGHSMTLGWKVPKFSGGSPILG 744 N+ G S + VI + + GI ++ G ++ + ++P P + Sbjct: 21041 NSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV--EIPVLGRPKPTVT 21098 Query: 745 YYLDKREVHHKNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 + K + K VN + + TIL ++ + + A N+ G + + Sbjct: 21099 W--KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG-----EVGDVI 21151 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 + +P P P + F EV + W P G P+S Y V+ R+ D+ W+ + Sbjct: 21152 TIQVHDIPGP-PTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 21210 Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE------PVLVEARPGTKEIS 917 T Y K + L G Y FRV+A N GVG P TS P V PGT +++ Sbjct: 21211 TTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPFKVPGPPGTPQVT 21268 Query: 918 A 918 A Sbjct: 21269 A 21269 Score = 136 bits (343), Expect = 1e-31 Identities = 112/417 (26%), Positives = 180/417 (43%), Gaps = 28/417 (6%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+++ V L+W+PP G + Y +EK ++ V T Sbjct: 21952 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV--ATNCHKTS 22009 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V L EG SY FRVL+ N +G+ P+E ++A + P PG++ T+ SV Sbjct: 22010 WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASE---RPLPPGKITLMDVTRNSVS 22066 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ G++ W C + + GL GE+Y FRV A Sbjct: 22067 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQ 22124 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI-TLLNCDGHSMTLGWKVPKFSGGSPILGYY 746 N G+S+ Q S + + + P+ T G + + VP +P + ++ Sbjct: 22125 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKV--DVPFIGRPTPAVTWH 22182 Query: 747 LDKREVHHKNWHEVNS-SPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D V K VN+ S ++LT+ + + + N AG + E Sbjct: 22183 KD--NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG-----EAIETLNV 22235 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P P P + EV S+ + W P Y G S ++ Y V+ R+ W V+ Sbjct: 22236 IVLDKPGP-PTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-A 22293 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGV-----GKPSDTSEPVLVEARPGTKEIS 917 T A +K L+ G Y FR+ A N G +P+ P V PGT ++ Sbjct: 22294 TVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 22350 Score = 134 bits (337), Expect = 6e-31 Identities = 174/771 (22%), Positives = 294/771 (38%), Gaps = 127/771 (16%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT-LEINRADFDDTATYSA 229 ++L ++G P P+ +W K+G I + A + + HT L I AD D+ TY Sbjct: 30154 IRLTIPIKGKPFPICKWTKEGQDISKRA------MIATSETHTELVIKEADRGDSGTYDL 30207 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 V N G+ + V V IG P S P + D+Q + V++R Sbjct: 30208 VLENKCGKKAVYIKVRV----------------IGSPNSPEGPLEYDDIQ-VRSVRVSWR 30250 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 + + +R P+A WY D ++ + SL L ++ Sbjct: 30251 PPADDGGADILGYILE--RREVPKAAWYTIDSRVRGT------------SLVVKGLKENV 30296 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCH-----DANRDYVIVTWK 404 E + + ++ G+S ++ +P+ P P + + D + V ++W Sbjct: 30297 EYHFRVSAENQFGISKP-----LKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 30351 Query: 405 PPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG 464 P S V GY+++R E T+ WV+ N + Y VTGL Y FR+ A N G Sbjct: 30352 RPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVG 30411 Query: 465 ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISR 524 +S S S+ V DP D P P + IS+ Sbjct: 30412 LSETSPASEPVVCKDPFD---------------------------KPSQPGELEILSISK 30444 Query: 525 NYVVLSWE-PPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF 583 + V L WE P GK+ L Y++E G +W++ N + ++ ++ + L+E Y F Sbjct: 30445 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE-RIKDKQFTIGGLLEATEYEF 30503 Query: 584 RVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG--RVLASRNTKTSVVVQWD-----RPK 636 RV + N GLS P I+ + APG + + TK Q RP Sbjct: 30504 RVFAENETGLSRPRRTAMSIKTK--LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 30561 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY---IFRVKAVNAVGMS 693 D+ Y G L + +K R + T EQ ++ A N VG Sbjct: 30562 --PDIKWYRF-----GKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEV 30614 Query: 694 ENSQESDVIKVQAALTVPSHP--------YGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 E S K+ T HP YG H M +G VP + + Sbjct: 30615 ETSS-----KLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT-------W 30662 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + ++ + + + ++ ++ + + ++K+ N+ G + Sbjct: 30663 FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI-----LDV 30717 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE-EDAGEWITVNQ 864 E P+ P + + S V+ WK P G S ++ Y V+ E ++ EW V+ Sbjct: 30718 EIQDKPDK-PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSS 30776 Query: 865 TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA---RPG 912 + ++ +L + Y FRV A N G+ P + S V++++ +PG Sbjct: 30777 AISVTT-CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG 30826 Score = 121 bits (304), Expect = 4e-27 Identities = 113/424 (26%), Positives = 188/424 (44%), Gaps = 38/424 (8%) Query: 493 GEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVV 551 G+KE I L+ PGPP V EIS++ ++WEPP G P++ Y ++K Sbjct: 19773 GKKEYTIVVKVLD----TPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDA 19828 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV 611 SW V + + S + V +L EGKSY FRV + N +G+ +P E ++A Sbjct: 19829 ERKSWSTVTTECSKTS--FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS----- 19881 Query: 612 PSAPGRVL---ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGY 666 PG V+ +K+S + W +P + ++GY VD + N W+ K + Sbjct: 19882 -QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRV-MKSLSL 19938 Query: 667 NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK---VQAALTVPSHPYGITLLNCD 723 ++ LT G++Y FRV A N G S+ + V + V L + P + L + Sbjct: 19939 -QYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLP-DLCYLAKE 19996 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + L K+P +P + + + + V SS T++ D + ++ Sbjct: 19997 NSNFRL--KIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKY 20053 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG-PAYDLTFCEVRDTSLVMLWKAPVYSGSS 842 I N+AG E + + +PG P + F EV ++ + W P G S Sbjct: 20054 TITLKNVAGTKEGT-------ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGS 20106 Query: 843 PVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 ++ Y ++ R+ +W+T + +V+ L +G Y FRV A N GVG+ S Sbjct: 20107 EITNYILEKRDSVNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGE-GLKS 20164 Query: 903 EPVL 906 EP++ Sbjct: 20165 EPIV 20168 Score = 111 bits (278), Expect = 4e-24 Identities = 93/324 (28%), Positives = 134/324 (41%), Gaps = 41/324 (12%) Query: 152 RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRI-ESNYG 210 +AP LR+ V + + L V G P P+V+WY+ G I A+ KYRI E G Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKGG 30983 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 H L I DD Y ATN G VS A+ L + +P Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-----------------LEVEVPAKIH 31026 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 +P T LE G GE V++K PD P W + L+ + + Sbjct: 31027 LPKT------LEGMGAVHALRGEVVSIKIPFSGKPD-----PVITWQKGQDLIDNNGHYQ 31075 Query: 331 MFFGEGQASLSFSH-LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDL 389 + SL F + + + D G Y + +R G+ + L V D P P + Sbjct: 31076 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADV-------PDPPRGV 31128 Query: 390 QCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFE 449 + D +RD V +TW P + S + Y V++C W++ A + +Y V LF Sbjct: 31129 KVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RETRYTVINLFG 31186 Query: 450 GRSYIFRVRAVNSAGISRPSRVSD 473 SY FRV A N G+S+PS S+ Sbjct: 31187 KTSYQFRVIAENKFGLSKPSEPSE 31210 Score = 102 bits (255), Expect = 2e-21 Identities = 131/585 (22%), Positives = 229/585 (39%), Gaps = 85/585 (14%) Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE--------ARPGTKE 915 QT+ + + LQ ++++ + +N +G S +++ +L E +P + + Sbjct: 7163 QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVD 7222 Query: 916 ISAGVDEQGNIYLGFDCQEMTDAS-QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDK 974 ++ G E G F C A + TW K EI +K+ V + + L + K Sbjct: 7223 LALG--ESGT----FKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGK 7276 Query: 975 EDLGTYSVSVSDTDGVSS-SFVLDPEELERLMALSNEIKNPTIPLKSELA-YEIFDKGRV 1032 D G Y+ S+ G S S L +E R + +++ I + E YE G Sbjct: 7277 GDAGQYTCYASNIAGKDSCSAQLGVQEPPRFI---KKLEPSRIVKQDEFTRYECKIGG-- 7331 Query: 1033 RFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQI 1092 SP+ + ++ E+ +S R+ + ++EM S+E+ G YT + Sbjct: 7332 ---------SPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM--HNLSVEDSGDYTCEA 7380 Query: 1093 HDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKV 1152 H+ + SS L V E F++K PH E L + +V L C++ Sbjct: 7381 HNAAGSASSSTSL------KVKEPPIFRKK-------PHPIETL-----KGADVHLECEL 7422 Query: 1153 ANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPKLSKKDHGEYKATLKDDRGQDV 1210 T V W KD + + E + + I + D GEY+ +D G D Sbjct: 7423 QGTPPFHV-SWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDT 7481 Query: 1211 SILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAK 1270 + IA K + +S + +++ T EG + +F D+ ++ Sbjct: 7482 CVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAE-PISVVWFKDKGEI-------- 7532 Query: 1271 ISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEF 1330 + S+++ I SE +A LQ + GKYT +I + E FA Sbjct: 7533 VRESDNIWISYSENIATLQFSRVEPANAGKYTCQI------------KNDAGMQECFATL 7580 Query: 1331 QQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH 1390 + A EK P+ + + G T L CTV G P+ WFK+ +++ Sbjct: 7581 SVLEPATIVEK---------PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK 7631 Query: 1391 FSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 + + K + I V DSG YS ++N G + ++ V Sbjct: 7632 YKISFFN-KVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV 7675 Score = 95.5 bits (236), Expect = 3e-19 Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 25/408 (6%) Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCN 660 ++ QD P+ P ++ K S V+ W P + + Y V+ C A Sbjct: 30717 VEIQDKPDKPTGP--IVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 30774 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 I + LT Y FRV A N G+S+ + S V+ +++ P P T+ Sbjct: 30775 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 30834 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 S + WK P GG+ I YYL+KRE W V + + T+ +V L EG Sbjct: 30835 AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLE 30894 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY--DLTFCEVRDTSLVMLWKAPVY 838 YEF++ NL G E S+ SE ++ +P P + +L VR S L V Sbjct: 30895 YEFRVKCENLGGESEWSEISEPITPKS-DVPIQAPHFKEELRNLNVRYQSNATL-VCKVT 30952 Query: 839 SGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG--- 894 P+ ++ +E A G + + L ++ + V++VRA N G Sbjct: 30953 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 31012 Query: 895 ------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYE 948 V P+ P +E G + A E +I + F + TW K + Sbjct: 31013 GTASLEVEVPAKIHLPKTLE---GMGAVHALRGEVVSIKIPFSGK---PDPVITWQKGQD 31066 Query: 949 EISDDERFKIETVGDHSKLYLKN-PDKEDLGTYSVSVSDTDGVSSSFV 995 I ++ +++ + L N +++D G Y V + G+ V Sbjct: 31067 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 31114 Score = 77.8 bits (190), Expect = 7e-14 Identities = 113/534 (21%), Positives = 206/534 (38%), Gaps = 93/534 (17%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K+ EI E+FKI G +L + N ED Y+ V D Sbjct: 2901 FECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-VCGNDQ 2959 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 VS++ + P + ++ N + TI + + YE SY++ Sbjct: 2960 VSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYE------------------GISYKW 3001 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + N E+ ++ +++ K T + + F + T+ GKA S ++L + Sbjct: 3002 LKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYV---- 3053 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDV- 1168 E + EF + H + V E+ C+V+ + + +W+KDD Sbjct: 3054 --------EARHIEFRK----HIKDI---KVLEKKRAMFECEVS--EPDITVQWMKDDQE 3096 Query: 1169 LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAM 1227 L T+ + E+ + LLIP D G+Y G +VS ++ + D I ++ Sbjct: 3097 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGRDVRIRSI 3152 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS--EHMRIGGSEEM 1285 + ++V+ E R + D++ +W +I+ E + + Sbjct: 3153 KK-------EVQVI---EKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRI 3202 Query: 1286 AWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGR 1345 + I E + D G+YTF G++ +L ++ + E Q Sbjct: 3203 HRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQELQP------------- 3247 Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVK-VEQAKYVSMT 1404 VT+ GK + G P P++ W+K +Q LS F K + + ++ Sbjct: 3248 --------VTVQSGKPARFCAVISGRPQPKISWYKEEQ--LLSTGFKCKFLHDGQEYTLL 3297 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPA 1458 + ED+ Y+ KN YG ++SV ++P++ P Q P PA Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSV-----EVPEVVSPDQEMPVYPPA 3346 Score = 76.6 bits (187), Expect = 2e-13 Identities = 115/523 (21%), Positives = 192/523 (36%), Gaps = 81/523 (15%) Query: 930 FDCQEMTDAS--QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 F+C +T A + TW K +EI + I VG+ L + K D G Y+ ++ Sbjct: 6290 FECH-VTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATND 6348 Query: 988 DGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHL---SPD 1044 G + + + +K P +K A ++ +G +Q E SP+ Sbjct: 6349 VG------------KDMCSAQLSVKEPPKFVKKLEASKVAKQGES---IQLECKISGSPE 6393 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 + ND E+ +S + + + ++ ++ S E+ G Y + H+G + S Sbjct: 6394 IKVSWFRNDSELHESWKYNMSFINSVALL--TINEASAEDSGDYICEAHNGVGDASCSTA 6451 Query: 1105 LIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL 1164 L A F +K P A + +V L C+++ T V W+ Sbjct: 6452 LTVKAPPV-----------FTQKPSPVGA-------LKGSDVILQCEISGTPPFEVV-WV 6492 Query: 1165 KD--DVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDD 1222 KD V + + L I L D GEY ++ G D + K Sbjct: 6493 KDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPR 6552 Query: 1223 MILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAK-ISSSEHMRIGG 1281 + +S +++ EG + + V W + I SE+ RI Sbjct: 6553 FVKKLSDTSTLIGDAVELRAIVEGFQ----------PISVVWLKDRGEVIRESENTRISF 6602 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + +A LQ+ P + GKY +I + E A + A EK Sbjct: 6603 IDNIATLQLGSPEASNSGKYICQI------------KNDAGMRECSAVLTVLEPARIIEK 6650 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQL-SEHFSVKVEQAKY 1400 P+ +T+ G L C V G P+ WFK+ +++ S+H + K Sbjct: 6651 ---------PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFIN--KV 6699 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIP 1443 S+ I D G YS +KN G K + TVSV+ +P Sbjct: 6700 ASLKIPCAEMSDKGLYSFEVKNSVG--KSNCTVSVHVSDRIVP 6740 Score = 72.4 bits (176), Expect = 3e-12 Identities = 107/522 (20%), Positives = 194/522 (37%), Gaps = 69/522 (13%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K +E+ +R KI+ +L + + D G Y+V Sbjct: 3077 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVS 3136 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASY-- 1047 + FV + R+ ++ E+ ++ +K R + DA + Sbjct: 3137 TAKLFVEGRDV--RIRSIKKEV-------------QVIEKQRAVVEFEVNEDDVDAHWYK 3181 Query: 1048 -----RFIINDRE--VSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQ 1100 F + +R V + IHR M + + G YT +++ Sbjct: 3182 DGIEINFQVQERHKYVVERRIHR-----------MFISETRQSDAGEYTFVA----GRNR 3226 Query: 1101 SSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETV 1160 SS+ L +A + P + L + + C V + + + Sbjct: 3227 SSVTLYVNA-----------------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPK 3269 Query: 1161 FKWLKDDVLYETETLPNLERGICE--LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218 W K++ L T E LL+ + +D Y K+D G + ++ + Sbjct: 3270 ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329 Query: 1219 VYDDMILAMSRVCGKSA--SPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSS 1274 V + + A +PL+ T EG R QC + ++KV+W KD KI S Sbjct: 3330 VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQC--RVSGTDLKVSWYSKDKKIKPS 3387 Query: 1275 EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFK 1334 R+ E+ L+I E +D+G YTF + + +LS +A + E + + Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHE--RIE 3445 Query: 1335 AAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVK 1394 E +I + + + G TC + P+ WFK ++I S+ S++ Sbjct: 3446 QEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR 3505 Query: 1395 VEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 +KY+ S+ I D G+Y+ N+YG T++V Sbjct: 3506 --SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 3545 Score = 71.6 bits (174), Expect = 5e-12 Identities = 119/575 (20%), Positives = 220/575 (38%), Gaps = 90/575 (15%) Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPS---DTSEPVLVEARPGTKEISAGV 920 + A+ YL +++ YV +A N G+ + S EP + + +++ G Sbjct: 4537 ENNVASLYLSGIEVKHDGKYV--CQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQG- 4593 Query: 921 DEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTY 980 + + + F + A W K +E++ ++KI S L + + +K+D G Y Sbjct: 4594 -DPATLQVKFSGTKEITAK---WFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEY 4649 Query: 981 SVSVSDTDGVSSSF----VLD---PEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVR 1033 + V + G SS VLD P + + + IK I L+ +A Sbjct: 4650 TFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAG--------- 4700 Query: 1034 FWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIH 1093 S S ++ +D+E+S SE ++ T +E+ + + GTYT Sbjct: 4701 --------SHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI--SQLEGTDSGTYTCSAT 4750 Query: 1094 DGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLH-WDVTEECEVRLVCKV 1152 + +Q S L TV K+ P+F E DV V+L V Sbjct: 4751 NKAGHNQCSGHL------TV-------------KEPPYFVEKPQSQDVNPNTRVQLKALV 4791 Query: 1153 ANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKK--DHGEYKATLKDDRGQDV 1210 T T+ KW KD+ + ++ + + + K D G Y L +D G Sbjct: 4792 GGTAPMTI-KWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTAT 4850 Query: 1211 SILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAK 1270 S + K I K SP+ VL + +C + T +++V+W + Sbjct: 4851 SKATLFVKEPPQFI--------KKPSPVLVLRNGQSTTFECQITG-TPKIRVSWYLDGNE 4901 Query: 1271 ISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEF 1330 I++ + I + +A QI ++ G Y E + S++L + E Sbjct: 4902 ITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIREL 4961 Query: 1331 QQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH 1390 + + +++ + L C V G P EV W KN+++I+ S+ Sbjct: 4962 KPVEVVKYSD---------------------VELECEVTGTPPFEVTWLKNNREIRSSKK 5000 Query: 1391 FSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 +++ ++ ++ I D+G+Y + N+ G Sbjct: 5001 YTL-TDRVSVFNLHITKCDPSDTGEYQCIVSNEGG 5034 Score = 71.2 bits (173), Expect = 7e-12 Identities = 143/693 (20%), Positives = 256/693 (36%), Gaps = 104/693 (15%) Query: 770 LTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSL 829 LTV+ L E ++ A N+AG E S P + ++ +P P LT V TS+ Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ-KPDPMDVLTGTNVTFTSI 7797 Query: 830 VMLWKAPVYSGSSPVS-GYFVDFREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRV 887 V G+ P S +F E G+ V+ + + A L D Q Y Sbjct: 7798 V--------KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT--- 7846 Query: 888 RAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSY 947 + +N GK S T+ + K ++ E+G + T TW K+ Sbjct: 7847 -CIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNG 7905 Query: 948 EEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS----FVLDPEELER 1003 ++ +R I T + L + + ED G Y+ + + G S +L+P + Sbjct: 7906 INVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVK 7965 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 + + L+ +LA +P+ + D ++ + ++ Sbjct: 7966 QLEPVKVSVGDSASLQCQLAG-----------------TPEIGVSWYKGDTKLRPTTTYK 8008 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 + + +V ++ I + G Y + + + +S F TV E+ Sbjct: 8009 MHF--RNNVATLVFNQVDINDSGEYICKAENSVGEVSAS------TFLTVQEQ------- 8053 Query: 1124 FLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETV-FKWLKDDVLYETETLPNLERGI 1182 K P F+ L DV E + +V A + E + W KD + PN++ Sbjct: 8054 ---KLPPSFSRQLR-DVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDS--PNVQTSF 8107 Query: 1183 CE----LLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGK---VYDDMILAMSRVCG 1232 + L I K + G+Y T + G S ++ GK +D + + V G Sbjct: 8108 LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVG 8167 Query: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 +SA +C + T +KV+W +I S +I E A L + + Sbjct: 8168 ESAD------------FECHVTG-TQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLK 8214 Query: 1293 PTEKDKGKYTFEIFD--GKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGL 1350 + D G+YT + GKD+ L++ + +F + L Sbjct: 8215 VDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-------------------RL 8255 Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 + V EG + L V G+ V W+KN+ +IQ + + + + V + ++ Sbjct: 8256 SETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV-LQVRKAGM 8314 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIP 1443 D+G Y+ + N G + + V K +K P Sbjct: 8315 NDAGLYTCKVSND-AGSALCTSSIVIKEPKKPP 8346 Score = 70.5 bits (171), Expect = 1e-11 Identities = 118/566 (20%), Positives = 206/566 (36%), Gaps = 92/566 (16%) Query: 885 FRVRAVNANGVGKPSDT---SEPVLVEARPGTKEISAGVDEQGNIYLGFDCQ-EMTDASQ 940 + A NA G S + EP + +P E G D + +C+ + T Sbjct: 7376 YTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGAD------VHLECELQGTPPFH 7429 Query: 941 FTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV-----SDTDGVSSSFV 995 +W K E+ +++KI + + +++ N D D+G Y SDT S + Sbjct: 7430 VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489 Query: 996 LDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDRE 1055 P +++L +S + V+ E P + F Sbjct: 7490 APPRFVKKLSDISTVVGK-----------------EVQLQTTIEGAEPISVVWFKDKGEI 7532 Query: 1056 VSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLE 1115 V +S+ I + I + R N G YT QI + + L +VLE Sbjct: 7533 VRESD--NIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL------SVLE 7584 Query: 1116 EAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETE 1173 A K K VT L C VA T E KW KD ++ + + Sbjct: 7585 PATIVEKPESIK------------VTTGDTCTLECTVAGTP-ELSTKWFKDGKELTSDNK 7631 Query: 1174 TLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQD--VSILEIAGK-VYDDMILAMSRV 1230 + + L I ++ D G Y +++ G+D + L+++ + V + Sbjct: 7632 YKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKET 7691 Query: 1231 CGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQI 1290 G S S + + C G + + V+W H+ +ISS + ++ L + Sbjct: 7692 NGLSGSSVVMECKVYG----------SPPISVSWFHEGNEISSGRKYQTTLTDNTCALTV 7741 Query: 1291 CEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGL 1350 E D G YT + +++G DE A + +F +K Sbjct: 7742 NMLEESDSGDYTCI----------ATNMAGS--DECSAPLTVREPPSFVQK--------- 7780 Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 PD + ++ G + T V G P V WFK ++ + +V +E + + + V + Sbjct: 7781 PDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS-VAELELFDVDT 7839 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVY 1436 SG+Y+ + N+ G K T +Y Sbjct: 7840 SQSGEYTCIVSNEAG--KASCTTHLY 7863 Score = 70.1 bits (170), Expect = 1e-11 Identities = 108/561 (19%), Positives = 201/561 (35%), Gaps = 85/561 (15%) Query: 885 FRVRAVNANGVGKPSDT---SEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQF 941 F RA N+ G S EP +PG+K++ G + L Q T + Sbjct: 4183 FTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPG----SAVCLKSTFQGSTPLT-I 4237 Query: 942 TWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG----VSSSFVLD 997 W K +E+ I S L L D GTY+ VS+ G ++ FV + Sbjct: 4238 RWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE 4297 Query: 998 PEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVS 1057 P + S +K ++LA ++ +P + NDRE+ Sbjct: 4298 PATFVEKLEPSQLLKKGDA---TQLACKVTG-------------TPPIKITWFANDREIK 4341 Query: 1058 DSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEA 1117 +S HR+ ++T ++ + IE+ G Y + + S ++I Sbjct: 4342 ESSKHRMSFVESTAVLRLT--DVGIEDSGEYMCEAQNEAGSDHCSSIVIV---------- 4389 Query: 1118 EFQRKEFLRKQGPHFA-EYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYET--ET 1174 K+ P+F E+ +V +E +V L+ +VA T + W KD+ + + + Sbjct: 4390 ---------KESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEI-TWFKDNTILRSGRKY 4439 Query: 1175 LPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKS 1234 ++ + L I K D GEY+ + ++ G + + + I + Sbjct: 4440 KTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR 4499 Query: 1235 ASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPT 1294 T +G + + V W +I+ +++R+ +A L + Sbjct: 4500 GGTAAFQATLKG----------SLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIE 4549 Query: 1295 EKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVV 1354 K GKY QA ++A + + +A I + Sbjct: 4550 VKHDGKYVC-----------------QAKNDAGIQ----RCSALLSVKEPATITEEAVSI 4588 Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 + +G L G + WFK+ Q++ L + + V + + I +DSG Sbjct: 4589 DVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI-LKIISTEKKDSG 4647 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 +Y+ ++N G ++V Sbjct: 4648 EYTFEVQNDVGRSSCKARINV 4668 Score = 70.1 bits (170), Expect = 1e-11 Identities = 151/729 (20%), Positives = 265/729 (36%), Gaps = 124/729 (17%) Query: 735 KFSGGSPI-LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 K +G SPI + ++ +K ++ ++ S + T L ++ L + + A N+AG Sbjct: 5822 KVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT-LQLNSLDSSDMGNYTCVAANVAGS 5880 Query: 794 GE------PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS-G 846 E +P K EP P L V TS++ G+ P Sbjct: 5881 DECRAVLTVQEPPSFVK-------EPEPLEVLPGKNVTFTSVIR--------GTPPFKVN 5925 Query: 847 YFVDFREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 +F RE G+ + + T A L D+ Q Y V +N G+ S T+ Sbjct: 5926 WFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT----CVVSNNAGQASCTTRLF 5981 Query: 906 LVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHS 965 + E K +S E G + T TW K I+ E+ I T Sbjct: 5982 VKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTC 6041 Query: 966 KLYLKNPDKEDLGTYSVSVSDTDG--VSSSFV--LDPE----ELERLMALSNEIKNPTIP 1017 L + N K D G YS + + G V + V L+P ELE L A + ++ Sbjct: 6042 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGD----SVS 6097 Query: 1018 LKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVM 1077 L+ ++A + V ++ L P YR + + +V Sbjct: 6098 LQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNN-----------------VATLVF 6138 Query: 1078 DRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLH 1137 ++ +I + G YT + + + S KTV E R+ P FA L Sbjct: 6139 NKVNINDSGEYTCKAENSIGTASS---------KTVFRIQE-------RQLPPSFARQLK 6182 Query: 1138 -WDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERG----ICELLIPKLSK 1192 + T V L C++ + V W +D VL + NL+ + L I + Sbjct: 6183 DIEQTVGLPVTLTCRLNGSAPIQVC-WYRDGVLLRDDE--NLQTSFVDNVATLKILQTDL 6239 Query: 1193 KDHGEYKATLKDDRGQDVSILEIAGK------VYDDMILAMSRVCGKSASPLKVLCTPEG 1246 G+Y + + G S + + +D +++ + G+SA Sbjct: 6240 SHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESAD---------- 6289 Query: 1247 IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIF 1306 +C + M++ W + +I + I L+I + + D G+YT + Sbjct: 6290 --FECHVTG-AQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQAT 6346 Query: 1307 DGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTC 1366 + S LS + + + + K A +G+++ L C Sbjct: 6347 NDVGKDMCSAQLSVKEPPKFVKKLEASKVAK--------------------QGESIQLEC 6386 Query: 1367 TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGG 1426 + G+P+ +V WF+ND ++ S +++ + +TI ++EDSG Y N G Sbjct: 6387 KISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAEDSGDYICEAHNGVGD 6445 Query: 1427 EKIDVTVSV 1435 ++V Sbjct: 6446 ASCSTALTV 6454 Score = 69.3 bits (168), Expect = 3e-11 Identities = 117/629 (18%), Positives = 243/629 (38%), Gaps = 91/629 (14%) Query: 823 EVRDTSLVMLWKAPVYS---GSSPVSGYFV---DFREEDAGEWITVNQTTTANRYLKVSD 876 ++ +T+ V+ A S GS P+S ++ +ED +I+ + L++ Sbjct: 5053 KIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVAT---LQIRS 5109 Query: 877 LQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEM- 935 + G + + +A N +GV + +LV+ E + VD + +C Sbjct: 5110 VDNGHSGRYTCQAKNESGVER---CYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAG 5166 Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSF- 994 T + W K ++I F + + + +++ K+D G Y+ V + G SS Sbjct: 5167 TPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDA 5226 Query: 995 ---VLD---PEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYR 1048 VLD P + + +++ +I ++ +++ + +++ + +S A YR Sbjct: 5227 YLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSL--PISAQWFKDGKEISTSAKYR 5284 Query: 1049 FIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGD 1108 + ++R VS + ++ +E+ YT ++ + S +L Sbjct: 5285 LVCHERSVS-----------------LEVNNLELEDTANYTCKVSNVAGDDACSGIL--- 5324 Query: 1109 AFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDV 1168 TV E F K ++ P E + + K K KW KDDV Sbjct: 5325 ---TVKEPPSFLVKPGRQQAIPD----------STVEFKAILKGTPPFK---IKWFKDDV 5368 Query: 1169 --LYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILA 1226 + + LE L + + G+Y + +D G D + + Sbjct: 5369 ELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFV-- 5426 Query: 1227 MSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286 K K++ + RL+C + + E++V W + ++ +S+ R+ + +A Sbjct: 5427 ------KKLEASKIVKAGDSSRLECKIAG-SPEIRVVWFRNEHELPASDKYRMTFIDSVA 5479 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 +Q+ + +D G + E N S S + + F F Sbjct: 5480 VIQMNNLSTEDSGDFICEA----QNPAGSTSCSTKVIVKEPPVFSSF------------- 5522 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIK 1406 P +V ++ ++L C + G P EV+W+K+ + ++ S+ + + + + S+ I Sbjct: 5523 ----PPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIHIL 5577 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 V + D G+Y +N+ G + TV + Sbjct: 5578 NVDTSDIGEYHCKAQNEVGSDTCVCTVKL 5606 Score = 68.6 bits (166), Expect = 4e-11 Identities = 127/607 (20%), Positives = 225/607 (37%), Gaps = 84/607 (13%) Query: 839 SGSSPVSG-YFVDFRE-EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 SGS P+S +F D +E + ++ V + + L+V++L+ T + + N G Sbjct: 5261 SGSLPISAQWFKDGKEISTSAKYRLVCHERSVS--LEVNNLELEDTANYTCKVSNVAGDD 5318 Query: 897 KPSD---TSEPVLVEARPGTKE-ISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 S EP +PG ++ I E I G T + W K E+ Sbjct: 5319 ACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKG------TPPFKIKWFKDDVELVS 5372 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 + I G S L L + D G Y+ V++ G S M L E Sbjct: 5373 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTT---------MLLVTEPP 5423 Query: 1013 NPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 L++ + D R+ + SP+ + N+ E+ S+ +R+ + + Sbjct: 5424 KFVKKLEASKIVKAGDSSRLECKIAG---SPEIRVVWFRNEHELPASDKYRMTFIDSVAV 5480 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 I+M + S E+ G + + + + S +I K+ P F Sbjct: 5481 IQM--NNLSTEDSGDFICEAQNPAGSTSCSTKVIV-------------------KEPPVF 5519 Query: 1133 AEYLHW-DVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPK 1189 + + + + EV L C+++ T V W KD + + + + I Sbjct: 5520 SSFPPIVETLKNAEVSLECELSGTPPFEVV-WYKDKRQLRSSKKYKIASKNFHTSIHILN 5578 Query: 1190 LSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRL 1249 + D GEY +++ G D + + K + ++ + + P ++ + EG + Sbjct: 5579 VDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQ- 5637 Query: 1250 QCFMKYFTDEMKVNWC-HKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDG 1308 + V W K+ I SE++RI E +A LQ + + GKY +I + Sbjct: 5638 ---------PIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKN- 5687 Query: 1309 KDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTV 1368 D R E A + A EK +T+ G+T L C V Sbjct: 5688 -DGGMR----------ENMATLMVLEPAVIVEK---------AGPMTVTVGETCTLECKV 5727 Query: 1369 FGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEK 1428 G P+ V W+K+ + + S+ K S+ I V +D+G Y+ ++N G Sbjct: 5728 AGTPELSVEWYKDGKLLTSSQKHKFSFYN-KISSLRILSVERQDAGTYTFQVQNNVGKSS 5786 Query: 1429 IDVTVSV 1435 V V Sbjct: 5787 CTAVVDV 5793 Score = 65.9 bits (159), Expect = 3e-10 Identities = 67/248 (27%), Positives = 102/248 (41%), Gaps = 30/248 (12%) Query: 30 DEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRY 89 +EY K A ++SS S R + + L + + R E+ E + R Sbjct: 32249 EEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRS 32308 Query: 90 QSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEER 149 + E R R S ++ + L+R + + D ++ + M+ L ++ T E + Sbjct: 32309 PT-----PERTRPRSPSPVS---SERSLSRFERSARFDIFSRYESMKAALKTQK-TSERK 32359 Query: 150 ----------ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE 199 + AP I +R+RSH V + + VQ PT V+WY +G + E Sbjct: 32360 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG---VELQE 32416 Query: 200 PGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVV--------RRFRG 251 K + GV TLEI DD+ TY AV TN G+ S A + V R Sbjct: 32417 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR 32476 Query: 252 DEEPFRSV 259 DEE RSV Sbjct: 32477 DEEVPRSV 32484 Score = 65.9 bits (159), Expect = 3e-10 Identities = 50/166 (30%), Positives = 76/166 (45%), Gaps = 22/166 (13%) Query: 1262 VNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTF--EIFDGKDNHQRSLDLS 1319 V W ++++SE R G S L I + + +D+G T + +G Q L LS Sbjct: 33068 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 33127 Query: 1320 GQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWF 1379 + D A AF + R + I EG+ + TC + G P PE+ WF Sbjct: 33128 KELSD----------APAFISQPRSQ---------NINEGQNVLFTCEISGEPSPEIEWF 33168 Query: 1380 KNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 KN+ I +S + S+ + Y S+ I+ + DSGKY+I KN G Sbjct: 33169 KNNLPISISSNVSISRSRNVY-SLEIRNASVSDSGKYTIKAKNFRG 33213 Score = 63.9 bits (154), Expect = 1e-09 Identities = 61/247 (24%), Positives = 97/247 (39%), Gaps = 22/247 (8%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + +L++ + E +++ G P P + W K+ +I P K RIE G Sbjct: 1556 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1614 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L+I+ D+A Y+A A N G+ +T V V + EP R + +P G + I Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAA 1674 Query: 274 THFDVQFLE------KFGVTFRREGETVTLKCTMLVTPDLKRVQPR-------------- 313 + L + G + +E + L + LKR P Sbjct: 1675 PELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTM 1734 Query: 314 -AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372 EW D L+ + +M G SL + + D G+ T R ++ G SA L V Sbjct: 1735 VVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794 Query: 373 RDADPLV 379 +D LV Sbjct: 1795 KDEKSLV 1801 Score = 62.8 bits (151), Expect = 2e-09 Identities = 67/264 (25%), Positives = 101/264 (38%), Gaps = 44/264 (16%) Query: 149 RISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESN 208 ++ P + +L S TV +L +++G VQW K+ + + +E RI Sbjct: 5605 KLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE--NIRITFV 5662 Query: 209 YGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS 268 V TL+ +A+ + Y N G A ++V EP Sbjct: 5663 ENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVL------EP------------- 5703 Query: 269 SMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 +EK G GET TL+C + TP+L EWY+D LL S+ Sbjct: 5704 ---------AVIVEKAGPMTVTVGETCTLECKVAGTPELS-----VEWYKDGKLLTSSQK 5749 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRD--ADPLVT------ 380 K F +SL + + D G YT ++ + G S +A + V D P T Sbjct: 5750 HKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNT 5809 Query: 381 -GAPGAPMDLQCHDANRDYVIVTW 403 G GA L+C A + V W Sbjct: 5810 GGVLGASCILECKVAGSSPISVAW 5833 Score = 62.0 bits (149), Expect = 4e-09 Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 123 RDKLDKYAIQQMMEDKLAWERHTFEERI-SRAPEILVRLRSHTVWERMSVKLCFTVQGFP 181 R+ D Y + M + K R T R+ R PE + L + T + +V+ T+ P Sbjct: 31662 REVYDYYCRRTMKKIK----RRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 31717 Query: 182 TPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTN 241 P V WYK G I KY ES+ G++ L IN DD A Y+ VA N +G+ S Sbjct: 31718 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 31777 Query: 242 AAVVV 246 A + V Sbjct: 31778 AKLTV 31782 Score = 61.6 bits (148), Expect = 5e-09 Identities = 105/502 (20%), Positives = 190/502 (37%), Gaps = 81/502 (16%) Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 T + TW K+ EI +++ + L++ D D G Y VS+ G S Sbjct: 4981 TPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCST 5040 Query: 996 LDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDRE 1055 L+ + +I+N T LKS ++ G SP S ++ +D+ Sbjct: 5041 --RVALKEPPSFIKKIENTTTVLKSSATFQSTVAG-----------SPPISITWLKDDQI 5087 Query: 1056 VSDSEIHRIKCDKATGIIEMVMDRFSIEN--EGTYTVQIHDGKAKSQSSLVLIGDAFKTV 1113 + + + I + +++ S++N G YT Q AK++S + AF V Sbjct: 5088 LDEDDNVYISFVDSVATLQI----RSVDNGHSGRYTCQ-----AKNESGVERC-YAFLLV 5137 Query: 1114 LEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYE 1171 E A+ K DVTE+ + L C VA T E KWLKD ++ Sbjct: 5138 QEPAQIVEKA------------KSVDVTEKDPMTLECVVAGT-PELKVKWLKDGKQIVPS 5184 Query: 1172 TETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQ---DVSILEIAGKV---YDDMIL 1225 + E + I + K+D G+Y +++D G D + + + + + Sbjct: 5185 RYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLT 5244 Query: 1226 AMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEM 1285 M +V G S I ++C + + + W +IS+S R+ E Sbjct: 5245 KMDKVLGSS------------IHMECKVS-GSLPISAQWFKDGKEISTSAKYRLVCHERS 5291 Query: 1286 AWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGR 1345 L++ +D YT ++ S A D+A + K GR Sbjct: 5292 VSLEVNNLELEDTANYTCKV-------------SNVAGDDACSGILTVKEPPSFLVKPGR 5338 Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 +PD T+ + G P ++ WFK+D ++ + +E + + + Sbjct: 5339 Q-QAIPD-------STVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSF-LNL 5389 Query: 1406 KGVTSEDSGKYSINIKNKYGGE 1427 V + +G+Y+ ++ N G + Sbjct: 5390 YSVDASKTGQYTCHVTNDVGSD 5411 Score = 61.6 bits (148), Expect = 5e-09 Identities = 73/333 (21%), Positives = 124/333 (37%), Gaps = 48/333 (14%) Query: 76 STQEDEEQENRSRYQSLVA--AYGEAKRQRFLS-ELAHLEEDVHLARSQARDKLDKYAIQ 132 ++Q +E+ RS + L AY + ++ E + +V ++ R+ L Y Sbjct: 32472 ASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 32531 Query: 133 QMMEDK-LAWERHTFEERISR-------APEILVRLRSHTVWERMSVKLCFTVQGFPTPV 184 E K A E + EE+ + A IL + RS TV+E S + G P P Sbjct: 32532 ASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT 32591 Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W + G ++ +A ++++ + T EI+ D YS V N+ G+ + Sbjct: 32592 VTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 32648 Query: 245 VVRRFRGDEEPFRS----------------------VGLPIGLPLSSMIP---------- 272 +++ R E+ S V P ++ P Sbjct: 32649 TIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEK 32708 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H V K + E K T +V + R + WY+D LKE+ + Sbjct: 32709 VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK-EVTWYKDGKKLKENGHFQFH 32767 Query: 333 FG-EGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 + +G L ++L + D+G Y I GG S Sbjct: 32768 YSADGTYELKINNLTESDQGEYVCEISGEGGTS 32800 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D+VTI G L L V G P+P++IW K D+++ L E S++ K + IK Sbjct: 29055 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY-TGKRATAVIKFCDRS 29113 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ +KN G + + V V V Sbjct: 29114 DSGKYTLTVKNASGTKAVSVMVKV 29137 Score = 59.3 bits (142), Expect = 3e-08 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 24/201 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++L L+ TV + C + G P P + WYK+ L+ K + + +T Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF---KCKFLHDGQEYT 3295 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L + A +D A Y+ A N +G +T+A++ SV +P + +P Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASL-------------SVEVPEVVSPDQEMPV 3342 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + T EG+ +C + T DLK WY D +K S++ +M Sbjct: 3343 --YPPAIITPLQDTVTSEGQPARFQCRVSGT-DLK-----VSWYSKDKKIKPSRFFRMTQ 3394 Query: 334 GEGQASLSFSHLHKDDEGLYT 354 E L + + +DEG YT Sbjct: 3395 FEDTYQLEIAEAYPEDEGTYT 3415 Score = 59.3 bits (142), Expect = 3e-08 Identities = 128/584 (21%), Positives = 200/584 (34%), Gaps = 125/584 (21%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F C+ + +W ++I F++ D +L + ED GTY+ S+ G Sbjct: 3364 FQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG 3423 Query: 990 -VSSSFVLDPE------------ELERLMALSNEIKNPTIPLKSELAY------EIFDKG 1030 VSS+ L E E+E M + IK PL+ L + EI Sbjct: 3424 QVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483 Query: 1031 RVRF-WLQAEHLSPDASYRFIINDREVSDSEIHR-------------------IKCDKAT 1070 VRF W +A ++ I + + +S EI R + C Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543 Query: 1071 GIIEMVMDRFSIENE-----------------GTYTVQI---HDGKAKSQSSLVLIGDAF 1110 + E F + GT ++ DG A S S I DA Sbjct: 3544 TVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAE 3603 Query: 1111 -KTVLE--------------------EAEFQRKEFLRKQGPHFAEYLH-WDVTEECEVRL 1148 K +LE A+ + E + PHF + L +V L Sbjct: 3604 NKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHL 3663 Query: 1149 VCKVANTKKETVFKWLKDDVLYETETLPN-------LERGICELLIPKLSKKDHGEYKAT 1201 C+V +K TV W KD + LP E I L IP KD G Y T Sbjct: 3664 ECQVDEDRKVTV-TWSKDG-----QKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCT 3717 Query: 1202 LKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMK 1261 ++ G + + + K P ++ E RL C +K + ++ Sbjct: 3718 ASNEAGSSSCSATVTVREPPSFV--------KKVDPSYLMLPGESARLHCKLKG-SPVIQ 3768 Query: 1262 VNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQ 1321 V W + ++S S +R+ A L I + +D G Y+ E + + S ++ Sbjct: 3769 VTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI--- 3825 Query: 1322 AFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKN 1381 K I L + I+ G L C V G E+ WFK+ Sbjct: 3826 -----------------VIKEPPSFIKTL-EPADIVRGTNALLQCEVSGTGPFEISWFKD 3867 Query: 1382 DQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + I+ S+ + + Q V + I S D G+Y + N+ G Sbjct: 3868 KKQIRSSKKYRL-FSQKSLVCLEIFSFNSADVGEYECVVANEVG 3910 Score = 59.3 bits (142), Expect = 3e-08 Identities = 137/640 (21%), Positives = 223/640 (34%), Gaps = 120/640 (18%) Query: 902 SEPVLVEARPGTKEISAGVDEQGNIYLGFDCQ-EMTDASQFTWCKSYEEISDDERFKIET 960 S V+V+ P V+ N + +C+ T + W K ++ +++KI + Sbjct: 5508 STKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIAS 5567 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSV-----SDTDGVSSSFVLDPEELERLMALSNEIKNPT 1015 H+ +++ N D D+G Y SDT + P + +L +L+ P Sbjct: 5568 KNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPA 5627 Query: 1016 -IPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIE 1074 + E A IF + WL+ ++E E I+ + Sbjct: 5628 ELQASIEGAQPIFVQ-----WLK---------------EKEEVIRESENIRITFVENVAT 5667 Query: 1075 MVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAE 1134 + + N G Y QI + ++ L+ VLE A + K GP Sbjct: 5668 LQFAKAEPANAGKYICQIKNDGGMRENMATLM------VLEPAVI-----VEKAGP---- 5712 Query: 1135 YLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLE--RGICELLIPKLSK 1192 + V E C L CKVA T + +V +W KD L + I L I + + Sbjct: 5713 -MTVTVGETCT--LECKVAGTPELSV-EWYKDGKLLTSSQKHKFSFYNKISSLRILSVER 5768 Query: 1193 KDHGEYKATLKDDRGQ-------DVSI----------LEIAGKVYDDMILAMSRVCGKSA 1235 +D G Y ++++ G+ DVS L+ G V + +V G + Sbjct: 5769 QDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAG--S 5826 Query: 1236 SPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHM--------RIGGSEEM-A 1286 SP+ V E ++ KY T N C S M + GS+E A Sbjct: 5827 SPISVAWFHEKTKIVSGAKYQTT-FSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRA 5885 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSL---------------------DLSGQAFDE 1325 L + EP K E+ GK+ S+ D F++ Sbjct: 5886 VLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFED 5945 Query: 1326 AFAEFQQFKA--------AAFAEKNRG------RLIGGLPDVV-------TIMEGKTLNL 1364 AE + F N G RL P ++ GK++ L Sbjct: 5946 TVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIIL 6005 Query: 1365 TCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKY 1424 T G V W K+ +I SE ++ V K + I T D+G+YS I+N+ Sbjct: 6006 ESTYTGTLPISVTWKKDGFNITTSEKCNI-VTTEKTCILEILNSTKRDAGQYSCEIENEA 6064 Query: 1425 GGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASASAAG 1464 G + VS + + ++ P + A + AG Sbjct: 6065 GRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAG 6104 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/337 (21%), Positives = 124/337 (36%), Gaps = 49/337 (14%) Query: 1129 GPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW------LKDDVLYETETLPNLERGI 1182 GP + +H E V+ VCK+ N + T W L++ YE E G+ Sbjct: 31568 GPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEI----TYEDGV 31623 Query: 1183 CELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK----VYDDMILAMSRVCGKSASPL 1238 L + ++K D G Y+ + +D G+D S E+ K VYD + + + Sbjct: 31624 AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTM 31683 Query: 1239 KVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL---QICEPTE 1295 ++L P L + K + + + + + W Q +P + Sbjct: 31684 RLLERPPEFTLPLYNK---------TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 31734 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKN-RGRLIGGLPDVV 1354 DK KYTFE D L ++ D+ AE+ + E + + +L L Sbjct: 31735 NDK-KYTFE----SDKGLYQLTINSVTTDDD-AEYTVVARNKYGEDSCKAKLTVTLHPPP 31788 Query: 1355 T----------------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA 1398 T EG+++ V G P P + W K+ Q + L + + E Sbjct: 31789 TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGL 31848 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 Y ++ I+ ED+G Y + N G + V Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885 Score = 58.9 bits (141), Expect = 3e-08 Identities = 104/506 (20%), Positives = 199/506 (39%), Gaps = 98/506 (19%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ T+ ++ W ++ E I D ++ I L +++ +D Y+VS+++ G Sbjct: 12659 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 12718 Query: 990 VS----SSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDA 1045 + ++ +++ E+L + PLK E +K V FW + L+ Sbjct: 12719 ENVKSAANLIVEEEDLRIVE-----------PLKD---IETMEKKSVTFWCKVNRLN--V 12762 Query: 1046 SYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVL 1105 + ++ N EV + DK ++ + F +EG Y V G+ KS + L++ Sbjct: 12763 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFP--DEGEYIVTA--GQDKSVAELLI 12818 Query: 1106 IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW-- 1163 I EA + E L Q VTE + C+++ K KW Sbjct: 12819 I---------EAPTEFVEHLEDQ----------TVTEFDDAVFSCQLSREKANV--KWYR 12857 Query: 1164 ----LKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219 +K+ Y+ E ++ R L+I D EY ++D + + A Sbjct: 12858 NGREIKEGKKYKFEKDGSIHR----LIIKDCRLDDECEYACGVEDRKSR-------ARLF 12906 Query: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279 +++ + + R P +L P G + + D+++V W + + + ++ Sbjct: 12907 VEEIPVEIIR------PPQDILEAP-GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQM 12959 Query: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 ++ LQIC+ +D+G+Y F D EA A+ + A Sbjct: 12960 MSEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIK 13003 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 ++ ++ DV GK L + P E WFK ++ + ++ EQ Sbjct: 13004 TADQDLVV----DV-----GKPLTMVVPYDAYPKAEAEWFKENEPLS-TKTIDTTAEQTS 13053 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + K D G+Y I ++NK+G Sbjct: 13054 FRILEAK---KGDKGRYKIVLQNKHG 13076 Score = 58.5 bits (140), Expect = 4e-08 Identities = 36/101 (35%), Positives = 61/101 (60%), Gaps = 6/101 (5%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + RL+S TV + V+L V G PTPVV++Y+DG+ I + + ++I +++ Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEE 254 L I A +D+ TYS ATN+ G+ ++ A ++V +G+EE Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV---QGEEE 198 Score = 58.2 bits (139), Expect = 6e-08 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207 E IS P I+ L+ TV K G P P W KDG I Q GKY++ Sbjct: 32846 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG---GKYKLSE 32902 Query: 208 NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253 + G LEI++ D D+ Y+ N+ G VS++ + ++ + E Sbjct: 32903 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTE 32948 Score = 57.8 bits (138), Expect = 8e-08 Identities = 60/265 (22%), Positives = 96/265 (36%), Gaps = 42/265 (15%) Query: 145 TFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR 204 + E ++ P + L+ V + V+L V G P V W K+ I + KY Sbjct: 4946 SIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSK---KYT 5002 Query: 205 IESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIG 264 + V L I + D DT Y + +N G S + V ++ E P Sbjct: 5003 LTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK-----EPP--------- 5048 Query: 265 LPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLK 324 F++K T + T + T+ +P + W +DD +L Sbjct: 5049 --------------SFIKKIENTTTVLKSSATFQSTVAGSPPIS-----ITWLKDDQILD 5089 Query: 325 ESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPG 384 E + F + A+L + G YT + + GV AFL V++ +V A Sbjct: 5090 EDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKS 5149 Query: 385 A------PMDLQCHDANRDYVIVTW 403 PM L+C A + V W Sbjct: 5150 VDVTEKDPMTLECVVAGTPELKVKW 5174 Score = 57.8 bits (138), Expect = 8e-08 Identities = 118/544 (21%), Positives = 191/544 (35%), Gaps = 82/544 (15%) Query: 893 NGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQ-EMTDASQFTWCKSYEEIS 951 NGVG S S + V+A P + + V + C+ T + W K +++ Sbjct: 6441 NGVGDAS-CSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVR 6499 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV-----SDTDGVSSSFVLDPEELERLMA 1006 + ++FKI + + L++ N + D+G Y SDT S F P +++L Sbjct: 6500 NSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSD 6559 Query: 1007 LSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKC 1066 S I + ++ E F V WL+ DR E + Sbjct: 6560 TSTLIGDA---VELRAIVEGFQPISV-VWLK---------------DRGEVIRESENTRI 6600 Query: 1067 DKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLR 1126 I + + N G Y QI + + S VL TVLE A + Sbjct: 6601 SFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVL------TVLEPARI-----IE 6649 Query: 1127 KQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLE--RGICE 1184 K P VT L C V T E KW KD ++ ++ + Sbjct: 6650 KPEP-------MTVTTGNPFALECVVTGTP-ELSAKWFKDGRELSADSKHHITFINKVAS 6701 Query: 1185 LLIPKLSKKDHGEYKATLKDDRGQD---VSILEIAGKVYDDMILAMSRVCGKSASPLKVL 1241 L IP D G Y +K+ G+ VS+ V I + V + + + Sbjct: 6702 LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLE 6761 Query: 1242 CTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKY 1301 C G + + V W +I S + SE + L + D G Y Sbjct: 6762 CRVSG----------SAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIY 6811 Query: 1302 TFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKT 1361 T + +++G DE A + +F + PD V ++ G + Sbjct: 6812 TCV----------AANVAGS--DECSAVLTVQEPPSFEQT---------PDSVEVLPGMS 6850 Query: 1362 LNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIK 1421 L T + G P +V WFK +++ E ++ +E + + V +SG YS + Sbjct: 6851 LTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF-VTELELFEVQPLESGDYSCLVT 6909 Query: 1422 NKYG 1425 N G Sbjct: 6910 NDAG 6913 Score = 57.0 bits (136), Expect = 1e-07 Identities = 109/586 (18%), Positives = 215/586 (36%), Gaps = 97/586 (16%) Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--------PGTKEISAGVDEQG 924 KV +GK + +R V G+ T++ A TK + E+G Sbjct: 12240 KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 12299 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 + +C+ + ++ W K+ EI ++++I G KL + + ED+ TY+ Sbjct: 12300 ATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 12358 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPD 1044 D S + + P +E L L++ ++ +K RF + E + Sbjct: 12359 KDFK-TSCNLNVVPPHVEFLRPLTD--------------LQVREKEMARF--ECELSREN 12401 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 A ++ + E+ + + I A I +V+++ +++E Y+ ++ + Sbjct: 12402 AKVKWFKDGAEIKKGKKYDIISKGAVRI--LVINKCLLDDEAEYSCEVRTART------- 12452 Query: 1105 LIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL 1164 TVLEE K + +V+E ++LVC+V+ E + W Sbjct: 12453 ---SGMLTVLEEEAVFTKNL-----------ANIEVSETDTIKLVCEVSKPGAEVI--WY 12496 Query: 1165 K-DDVLYETETLPNLERGICELL-IPKLSKKDHGEYKATLKDDRGQ-DVSILEIAGKVYD 1221 K D+ + ET L G +L I +D G Y L R V + E+A + Sbjct: 12497 KGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFI- 12555 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGG 1281 L++L EG + + + V W D + S + + Sbjct: 12556 -----------SKPQNLEIL---EGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIA 12601 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + L + + T +D G Y + + AA Sbjct: 12602 DGKKRVLVVKDATLQDMGTYVVMVGAAR------------------------AAAHLTVI 12637 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV 1401 + R++ L D + E + + C V + WF+N++ I S + + + Y Sbjct: 12638 EKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY- 12694 Query: 1402 SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 ++ I+ +D Y++++ N + GE + ++ E + + P Sbjct: 12695 TLRIRDAHLDDQANYNVSLTN-HRGENVKSAANLIVEEEDLRIVEP 12739 Score = 56.6 bits (135), Expect = 2e-07 Identities = 54/225 (24%), Positives = 85/225 (37%), Gaps = 36/225 (16%) Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 + P + ++ + T + S TV G P + W KD ++ E I Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQIL---DEDDNVYISFVD 5100 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 V TL+I D + Y+ A N G A ++V +EP Sbjct: 5101 SVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLV------QEP-------------- 5140 Query: 270 MIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWT 329 Q +EK E + +TL+C + TP+LK +W +D + S++ Sbjct: 5141 --------AQIVEKAKSVDVTEKDPMTLECVVAGTPELK-----VKWLKDGKQIVPSRYF 5187 Query: 330 KMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRD 374 M F AS + K D G YT ++ + G S A+L V D Sbjct: 5188 SMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD 5232 Score = 56.2 bits (134), Expect = 2e-07 Identities = 98/501 (19%), Positives = 188/501 (37%), Gaps = 63/501 (12%) Query: 948 EEISD----DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EEIS E K+ KL LK + L + V S + S V EE+ + Sbjct: 32970 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIV--HEEITK 33027 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 S E++ +K+ ++G+ R L+A +++ ++++N E+++SE +R Sbjct: 33028 TSQASEEVRTHA-EIKAFSTQMSINEGQ-RLVLKA-NIAGATDVKWVLNGVELTNSEEYR 33084 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 + + + E T + +G K Q L L KE Sbjct: 33085 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL---------------SKE 33129 Query: 1124 FLRKQGPHF-AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERG- 1181 P F ++ ++ E V C+++ + +W K+++ + ++ R Sbjct: 33130 L--SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEI-EWFKNNLPISISSNVSISRSR 33186 Query: 1182 -ICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKV 1240 + L I S D G+Y K+ RGQ + + M+L + + V Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL-------MVLPLVEEPSREV----V 33235 Query: 1241 LCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGK 1300 L T LQ + + ++++ ++A SS EM + + + Sbjct: 33236 LRTSGDTSLQG--SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM-- 33291 Query: 1301 YTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG-----RLIGGLPDVVT 1355 + +++S +F + Q +++ G I LP ++ Sbjct: 33292 -----------QESFVEMSSSSF-MGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDIS 33339 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVTSEDSG 1414 I EGK L + C G P PEV W + I E +E ++ I V +D G Sbjct: 33340 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGG 33399 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 Y++++ N++G + V + + Sbjct: 33400 LYTLSLGNEFGSDSATVNIHI 33420 Score = 55.5 bits (132), Expect = 4e-07 Identities = 40/202 (19%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Query: 1247 IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIF 1306 ++ C ++ + +V W ++ +SE I + +A L + + T+ D G Y ++ Sbjct: 31585 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 31644 Query: 1307 DGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK-NRGRLIGGLPDVV------TIMEG 1359 + +L + E + + + + + RL+ P+ T G Sbjct: 31645 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 31704 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH---FSVKVEQAKYVSMTIKGVTSEDSGKY 1416 + + T+ +P+P V W+K+ Q I+ ++ ++ + ++ Y +TI VT++D +Y Sbjct: 31705 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEY 31763 Query: 1417 SINIKNKYGGEKIDVTVSVYKH 1438 ++ +NKYG + ++V H Sbjct: 31764 TVVARNKYGEDSCKAKLTVTLH 31785 Score = 55.5 bits (132), Expect = 4e-07 Identities = 69/264 (26%), Positives = 108/264 (40%), Gaps = 19/264 (7%) Query: 12 RHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLS-QRSSSQRASSQTSLGGTICRV 70 R S Q + L E ASK S + + S ++S ++TS R Sbjct: 32978 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRT 33037 Query: 71 CA--KRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEE--------DVHLARS 120 A K STQ + R ++ +A + K EL + EE D L Sbjct: 33038 HAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK 33097 Query: 121 QA--RDKLDKYAIQQMMEDKLAWERH-TFEERISRAPEILVRLRSHTVWERMSVKLCFTV 177 QA RD+ I + E + + T + +S AP + + RS + E +V + Sbjct: 33098 QASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI 33157 Query: 178 QGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQ 237 G P+P ++W+K+ I ++ I + V++LEI A D+ Y+ A N GQ Sbjct: 33158 SGEPSPEIEWFKNNLPISISS---NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ 33214 Query: 238 VSTNAAVVVRRFRGDEEPFRSVGL 261 S A+++V EEP R V L Sbjct: 33215 CSATASLMVLPL--VEEPSREVVL 33236 Score = 55.1 bits (131), Expect = 5e-07 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 +P+ +TI GK L + V+G P P W K + ++ S H +V + + + IK VT Sbjct: 18904 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVT 18962 Query: 1410 SEDSGKYSINIKNKYG--GEKIDVTV 1433 +DSG YS+ +N G +KI V V Sbjct: 18963 RKDSGYYSLTAENSSGTDTQKIKVVV 18988 Score = 54.7 bits (130), Expect = 6e-07 Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 29/243 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P ++ L++ TV E SV L + G+P+P V WY++ I + + ++I G+ Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIAR 999 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVR--------------RFRGDEEPFRS- 258 L I A +D+ ++ A N G VST+ + V+ +F +E+ F Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059 Query: 259 ---VGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAE 315 V L P F+ K V EG +V C + P +P Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVY 1114 Query: 316 WYRDDVLLKESKWTKMFFGE--GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W + V L K+ + + G+ L S DD G YT+ + ++ G + SA L + Sbjct: 1115 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LE 1173 Query: 374 DAD 376 +AD Sbjct: 1174 EAD 1176 Score = 54.7 bits (130), Expect = 6e-07 Identities = 50/192 (26%), Positives = 80/192 (41%), Gaps = 39/192 (20%) Query: 185 VQWYKDGSLICQAAEPGK-YRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAA 243 V W KDG Q PGK Y+I + TLEI A D+ TY A+N G S +A Sbjct: 3675 VTWSKDG----QKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSAT 3730 Query: 244 VVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF-RREGETVTLKCTML 302 V VR E P F++K ++ GE+ L C + Sbjct: 3731 VTVR-----EPP-----------------------SFVKKVDPSYLMLPGESARLHCKLK 3762 Query: 303 VTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGG 362 +P + + W++++ L ES +M+F +A L + + +D G Y+ V+ G Sbjct: 3763 GSPVI-----QVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVG 3817 Query: 363 VSDHSAFLFVRD 374 S + +++ Sbjct: 3818 SDSCSTEIVIKE 3829 Score = 53.9 bits (128), Expect = 1e-06 Identities = 65/276 (23%), Positives = 95/276 (34%), Gaps = 45/276 (16%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P L R +S T + + K TV G P W KDG+ + + +RI H Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPN---WRISDAENKHI 3607 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 LE++ D YS A+N G A +++ D+ F P+ ++ + Sbjct: 3608 LELSNLTIQDRGVYSCKASNKFGADICQAELIII----DKPHFIKELEPVQSAINKKV-- 3661 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 H + Q E VT W +D L K K+ F Sbjct: 3662 -HLECQVDEDRKVT--------------------------VTWSKDGQKLPPGKDYKICF 3694 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL-------FVRDADPLVTGAPGAP 386 + A+L D G Y + G S SA + FV+ DP PG Sbjct: 3695 EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGES 3754 Query: 387 MDLQCHDANRDYVIVTWKPPN--TTTESPVMGYFVD 420 L C + VTW N + + V YFV+ Sbjct: 3755 ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVN 3790 Score = 52.8 bits (125), Expect = 2e-06 Identities = 62/264 (23%), Positives = 99/264 (37%), Gaps = 42/264 (15%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 E + AP I ++ V K +Q P QW+K G I E K I Sbjct: 3449 EMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY---ESDKCSIR 3505 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 S+ + +LEI R D Y+ A+N +G VS A + V E + L Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT------EAYPPTFLSRPKS 3559 Query: 267 LSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKES 326 L++ + G+ CT+ TP ++ + W +D L S Sbjct: 3560 LTTFV--------------------GKAAKFICTVTGTPVIETI-----WQKDGAALSPS 3594 Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL-------FVRDADPLV 379 ++ E + L S+L D G+Y+ + ++ G A L F+++ +P V Sbjct: 3595 PNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEP-V 3653 Query: 380 TGAPGAPMDLQCHDANRDYVIVTW 403 A + L+C V VTW Sbjct: 3654 QSAINKKVHLECQVDEDRKVTVTW 3677 Score = 52.8 bits (125), Expect = 2e-06 Identities = 56/250 (22%), Positives = 88/250 (35%), Gaps = 48/250 (19%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 SV L V G P V WYK + + E YR V TL N+ + +D+ Y+ Sbjct: 6095 SVSLQCQVAGTPEITVSWYKGDTKLRPTPE---YRTYFTNNVATLVFNKVNINDSGEYTC 6151 Query: 230 VATNAHGQVSTNAAVVVRRFR---GDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGV 286 A N+ G S+ ++ + + + +GLP++ + Sbjct: 6152 KAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVT-----------------L 6194 Query: 287 TFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLH 346 T R G C WYRD VLL++ + + F + A+L Sbjct: 6195 TCRLNGSAPIQVC----------------WYRDGVLLRDDENLQTSFVDNVATLKILQTD 6238 Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVR--------DADPL-VTGAPGAPMDLQCHDANRD 397 G Y+ + G + SA L R D P+ + G D +CH Sbjct: 6239 LSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQ 6298 Query: 398 YVIVTWKPPN 407 + +TW N Sbjct: 6299 PMRITWSKDN 6308 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L+ GL +V T++EG+++ L C + G P P V W++ D I+ S F + Q+ + I Sbjct: 945 LVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMI 1002 Query: 1406 KGVTSEDSGKYSINIKNKYG 1425 + +EDSG+++ + N+ G Sbjct: 1003 REAFAEDSGRFTCSAVNEAG 1022 Score = 52.0 bits (123), Expect = 4e-06 Identities = 51/223 (22%), Positives = 91/223 (40%), Gaps = 31/223 (13%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 ++AP L+S V E + + GFP P V W++DG +I + PG +I + G Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPG-VQISFSDG 61 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 L I ++ YS ATN GQ ++ A ++V + + P Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV---KAETAP--------------- 103 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 F+++ R+G V L+ + P P ++YRD ++ S + Sbjct: 104 -------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLDFQ 151 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 + SL + + +D G Y++ + G + +A L V+ Sbjct: 152 ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 52.0 bits (123), Expect = 4e-06 Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 27/207 (13%) Query: 1245 EGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFE 1304 E + L+C + + V W +D +I SS +I +A L I E +D G++T Sbjct: 958 ESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 1016 Query: 1305 IFDGKDNHQRSLDLSGQAFDE-----------------AFAEFQQ--FKAAAFAEKNRGR 1345 + S L+ Q +E F E + + E+ G Sbjct: 1017 AVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGP 1076 Query: 1346 LIGGLPDVVT------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKV-EQA 1398 P +T ++EG ++ C V GNP P V W K+ + + V +Q Sbjct: 1077 GEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1136 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + I ++D+G+Y+I ++NK+G Sbjct: 1137 GECKLVISMTFADDAGEYTIVVRNKHG 1163 Score = 52.0 bits (123), Expect = 4e-06 Identities = 57/240 (23%), Positives = 91/240 (37%), Gaps = 42/240 (17%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 V G P + WYK+ + + A Y+++ V +L IN+ D D YS A N+ G Sbjct: 7043 VDGTPEIRISWYKEHTKLRSAPA---YKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG 7099 Query: 237 QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVT 296 V+++A +V++ + LP P+ F K G V Sbjct: 7100 AVASSAVLVIKARK----------LP---------PF------FARKLKDVHETLGFPVA 7134 Query: 297 LKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLR 356 +C + + L + WY+D VLLK+ + F A+L + G Y Sbjct: 7135 FECRINGSEPL-----QVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 7189 Query: 357 IVSRGGVSDHSAFLFVR--------DADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPN 407 + G + SA L + D P+ V A G +CH + +TW N Sbjct: 7190 ASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDN 7249 Score = 50.8 bits (120), Expect = 9e-06 Identities = 113/619 (18%), Positives = 230/619 (37%), Gaps = 109/619 (17%) Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---GTKEISAGVDEQGNIYL 928 L + D+ + V+A+N G + + +LV+A+ T+E+ V ++ + Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAG---ETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192 Query: 929 GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 F+C+ + W K E+ + +++++ + L + D D YS + + + Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE 2252 Query: 989 GVSSS-----------FVLDPEELERLMALSNEIK-------------NPTIPLKSELAY 1024 V ++ FV + +++E + S E++ + + LKS Y Sbjct: 2253 NVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKY 2312 Query: 1025 EIFDK-GRVRFWLQAEHLSPDASYRFIIN----------------------DREVSDSEI 1061 I + GR ++ Y F+I+ D++V + +I Sbjct: 2313 TITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDI 2372 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +++ + +E V + E + + V I K QS ++LI D K F Sbjct: 2373 VQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK---QSHMLLIEDMTKEDAGNYSFTI 2429 Query: 1122 KEFLRKQGPHFAEYL--------HWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE 1173 + Y +V E + L CKV+ +V +L D+ + + Sbjct: 2430 PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDD 2489 Query: 1174 TLPNLERGICE-LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCG 1232 + + +G + L+I + D G YK I G+V + L++ ++ Sbjct: 2490 RVQAIVKGTKQRLVINRTHASDEGPYKL--------------IVGRVETNCNLSVEKI-- 2533 Query: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 K L+ L E + ++ + V W KD +I S +I ++ L + Sbjct: 2534 KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLN 2593 Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352 + D+GKYTF + G++ L ++G A + + Sbjct: 2594 MMKDDEGKYTF--YAGENMTSGKLTVAGGAISKPLTD----------------------- 2628 Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 T+ E + C V NPD + W ++ + + L+ + + + K + I +D Sbjct: 2629 -QTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKR-RLIIAATKLDD 2685 Query: 1413 SGKYSINIKNKYGGEKIDV 1431 G+Y+ + K+ V Sbjct: 2686 IGEYTYKVATSKTSAKLKV 2704 Score = 50.8 bits (120), Expect = 9e-06 Identities = 59/283 (20%), Positives = 107/283 (37%), Gaps = 31/283 (10%) Query: 1184 ELLIPKLSKKDHGEYKATLKDDRGQDVSI----LEIAGKVYDDMILAMSRVCGKSASPLK 1239 +L I + +D G Y + GQ S LE + + I + K+A +K Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIK 3459 Query: 1240 VLCTPEGIRLQCFMKYFTD-----EMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPT 1294 P + L K+ + ++ W +I S+ I S+ ++ L+I Sbjct: 3460 RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQ 3519 Query: 1295 EKDKGKYTFEIFDGKDNHQRSLDLS-GQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDV 1353 D G+YT + + + + L+ +A+ F P Sbjct: 3520 VVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLS--------------------RPKS 3559 Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 +T GK CTV G P E IW K+ + S ++ + + K++ + + +T +D Sbjct: 3560 LTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHI-LELSNLTIQDR 3618 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLI 1456 G YS NK+G + + + I ++ P Q A K + Sbjct: 3619 GVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKV 3661 Score = 50.8 bits (120), Expect = 9e-06 Identities = 67/281 (23%), Positives = 113/281 (40%), Gaps = 48/281 (17%) Query: 152 RAPEILV-RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 +AP V RL +++ + + L T G P V W K+G + + + I + Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQ---RCNITTTEK 7921 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 LEI + +D Y+ NA G+ S +A +++ EP Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL------EP--------------- 7960 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 PY V+ LE V+ G++ +L+C + TP++ WY+ D L+ + K Sbjct: 7961 -PYF---VKQLEPVKVSV---GDSASLQCQLAGTPEIG-----VSWYKGDTKLRPTTTYK 8008 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD---------PLVTG 381 M F A+L F+ + +D G Y + + G S FL V++ V Sbjct: 8009 MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQE 8068 Query: 382 APGAPMDLQCHDANRDYVIVTW-KPPNTTTESP-VMGYFVD 420 G P+ C + + + V+W K +SP V F+D Sbjct: 8069 TVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD 8109 Score = 50.4 bits (119), Expect = 1e-05 Identities = 58/228 (25%), Positives = 86/228 (37%), Gaps = 49/228 (21%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 QW+KDG I +A KYR+ + +LE+N + +DTA Y+ +N G + + + Sbjct: 5269 QWFKDGKEISTSA---KYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILT 5325 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTP 305 V+ E P FL K G TV K + TP Sbjct: 5326 VK-----EPP-----------------------SFLVKPGRQQAIPDSTVEFKAILKGTP 5357 Query: 306 DLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD---EGLYTLRIVSRGG 362 K +W++DDV L K F G + S SF +L+ D G YT + + G Sbjct: 5358 PFK-----IKWFKDDVELVSG--PKCFIGL-EGSTSFLNLYSVDASKTGQYTCHVTNDVG 5409 Query: 363 VSDHSAFL-------FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTW 403 + L FV+ + G L+C A + V W Sbjct: 5410 SDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457 Score = 50.4 bits (119), Expect = 1e-05 Identities = 66/254 (25%), Positives = 93/254 (36%), Gaps = 45/254 (17%) Query: 159 RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINR 218 RL +V + L T G P V W KD LI Q+ E + LEI Sbjct: 6932 RLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKST---ILEILE 6988 Query: 219 ADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDV 278 + +D A YS + N GQ A V V EP PY Sbjct: 6989 STIEDYAQYSCLIENEAGQDICEALVSVL------EP----------------PY----- 7021 Query: 279 QFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQA 338 F+E GE TL+C + TP++ R WY++ L+ + KM F A Sbjct: 7022 -FIEPLEHVEAVIGEPATLQCKVDGTPEI-----RISWYKEHTKLRSAPAYKMQFKNNVA 7075 Query: 339 SLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV--RDADPL-------VTGAPGAPMDL 389 SL + + D G Y+ + + G SA L + R P V G P+ Sbjct: 7076 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAF 7135 Query: 390 QCHDANRDYVIVTW 403 +C + + V+W Sbjct: 7136 ECRINGSEPLQVSW 7149 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 6/107 (5%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P +T+ EG++ +C G P P V W + Q + S V + K + I V + Sbjct: 32567 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQA 32625 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA---PPQQAKPK 1454 D G YS+ ++N G ++ + T+++ K ++ + A PP+ P+ Sbjct: 32626 SDEGNYSVVVENSEGKQEAEFTLTIQK--ARVTEKAVTSPPRVKSPE 32670 Score = 49.7 bits (117), Expect = 2e-05 Identities = 54/214 (25%), Positives = 77/214 (35%), Gaps = 40/214 (18%) Query: 175 FTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNA 234 +TV G P +WYKDG + + KYRI V L+ A+ D+ Y+ +N Sbjct: 4038 YTVAGTPELKPKWYKDGRPLVASK---KYRISFKNNVAQLKFYSAELHDSGQYTFEISNE 4094 Query: 235 HGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGET 294 G S V D PF F R Sbjct: 4095 VGSSSCETTFTV--LDRDIAPF---------------------------FTKPLRNVDSV 4125 Query: 295 VTLKCTMLVTPDLK---RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 V C + D K + R W++D + S ++ F EG ASL + +D G Sbjct: 4126 VNGTCRL----DCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAG 4181 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGA 385 +T R + G D S L V++ VT PG+ Sbjct: 4182 NFTCRATNSVGSKDSSGALIVQEPPSFVT-KPGS 4214 Score = 49.7 bits (117), Expect = 2e-05 Identities = 123/610 (20%), Positives = 219/610 (35%), Gaps = 104/610 (17%) Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKT-------YVFRVRA 889 + G P+S ++ +D GE I ++ T + ++ LQ G Y+ +++ Sbjct: 6573 IVEGFQPISVVWL----KDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIK- 6627 Query: 890 VNANGVGKPS---DTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEM-TDASQFTWCK 945 N G+ + S EP + +P ++ G +C T W K Sbjct: 6628 -NDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNP------FALECVVTGTPELSAKWFK 6680 Query: 946 SYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLM 1005 E+S D + I + + L + + D G YS V ++ G S+ V +R++ Sbjct: 6681 DGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTV-SVHVSDRIV 6739 Query: 1006 ALS--NEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 S ++K+ L + + E G S S + + E+ Sbjct: 6740 PPSFIRKLKDVNAILGASVVLECRVSG-----------SAPISVGWFQDGNEIVSGP--- 6785 Query: 1064 IKCDKA--TGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 KC + + + + + G YT + + S VL TV E F+ Sbjct: 6786 -KCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL------TVQEPPSFE- 6837 Query: 1122 KEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLP----- 1176 Q P E L + + T V KW K E +P Sbjct: 6838 ------QTPDSVEVL-----PGMSLTFTSVIRGTPPFKV-KWFKGS----RELVPGESCN 6881 Query: 1177 -NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSA 1235 +LE + EL + ++ + G+Y + +D G + K + ++ ++ Sbjct: 6882 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETG 6941 Query: 1236 SPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTE 1295 SP+ + T G T + V+W + IS SE I +E+ L+I E T Sbjct: 6942 SPIVLEATYTG----------TPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTI 6991 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVT 1355 +D +Y+ I +N +GQ EA + F E L V Sbjct: 6992 EDYAQYSCLI----ENE------AGQDICEALVSV--LEPPYFIEP--------LEHVEA 7031 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 ++ G+ L C V G P+ + W+K ++ + + ++ + S+ I V D G+ Sbjct: 7032 VI-GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKN-NVASLVINKVDHSDVGE 7089 Query: 1416 YSINIKNKYG 1425 YS N G Sbjct: 7090 YSCKADNSVG 7099 Score = 48.9 bits (115), Expect = 4e-05 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P+ V ++EG+T C V G P P+V W+ N Q I+ S+ F V+ + Y + I S Sbjct: 1847 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY--LDIVDCKS 1904 Query: 1411 EDSGKYSINIKNKYG 1425 D+G+ + +N G Sbjct: 1905 YDTGEVKVTAENPEG 1919 Score = 48.5 bits (114), Expect = 5e-05 Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 26/207 (12%) Query: 1261 KVNWCHKDAKISSSE--HMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDL 1318 +V+W IS+S ++I S+ A L I T+ + G+Y+ + +G Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNG---------- 85 Query: 1319 SGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIW 1378 SGQA A + AE + L + T+ +G + L V G P P V + Sbjct: 86 SGQATSTA-------ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKF 137 Query: 1379 FKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKH 1438 +++ +IQ S F + E Y S+ I EDSG YS+N N G + T + Sbjct: 138 YRDGAEIQSSLDFQISQEGDLY-SLLIAEAYPEDSGTYSVNATNSVG--RATSTAELLVQ 194 Query: 1439 GEKIPDMAPPQQAKPKLIPASASAAGQ 1465 GE + P ++ K + A S + Q Sbjct: 195 GE---EEVPAKKTKTIVSTAQISESRQ 218 Score = 48.5 bits (114), Expect = 5e-05 Identities = 113/584 (19%), Positives = 203/584 (34%), Gaps = 78/584 (13%) Query: 890 VNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEE 949 V AN VGK + +L E K++ + G ++ TW K E Sbjct: 3904 VVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963 Query: 950 ISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS----FVLDPEEL-ERL 1004 I +D + K+ + L + + G Y+ + G +S V +P ++ ER Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERA 4023 Query: 1005 MALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRI 1064 + +P + L Y + +P+ ++ + R + S+ +RI Sbjct: 4024 ELIQVTAGDP-----ATLEYTVAG-------------TPELKPKWYKDGRPLVASKKYRI 4065 Query: 1065 KCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEF 1124 + ++ + + G YT +I + S TVL+ Sbjct: 4066 SFKN--NVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTF------TVLD--------- 4108 Query: 1125 LRKQGPHFAEYL-HWDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETETLPNLERG 1181 R P F + L + D RL CK+A + V W KD ++ G Sbjct: 4109 -RDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRV-SWFKDGKEIAASDRYRIAFVEG 4166 Query: 1182 ICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVL 1241 L I ++ D G + + G S + + +++ K P + Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSS---GALIVQEPPSFVTKPGSKDVLPGSAV 4223 Query: 1242 CTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKY 1301 C + + + + W + ++ S I + L++ D G Y Sbjct: 4224 CLKSTFQ-------GSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTY 4276 Query: 1302 TFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKT 1361 T ++ N ++ S F + + A F EK L + +G Sbjct: 4277 TCKV----SNVAGGVECSANLFVK--------EPATFVEK--------LEPSQLLKKGDA 4316 Query: 1362 LNLTCTVFGNPDPEVIWFKNDQDI-QLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINI 1420 L C V G P ++ WF ND++I + S+H VE + +T G+ EDSG+Y Sbjct: 4317 TQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGI--EDSGEYMCEA 4374 Query: 1421 KNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASASAAG 1464 +N+ G + V V + + P + K + A AG Sbjct: 4375 QNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAG 4418 Score = 48.5 bits (114), Expect = 5e-05 Identities = 124/606 (20%), Positives = 230/606 (37%), Gaps = 106/606 (17%) Query: 832 LWKAPVYSGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 L+ V+ G + + + ++ E D G+W Q TA+ ++ ++ GK ++ + Sbjct: 11757 LYGVEVFVGET--AHFEIELSEPDVHGQWKLKGQPLTASPDCEI--IEDGKKHILILHNC 11812 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEIS-------AGVDEQGNIYLGFDCQEMTDASQFTW 943 G+ S + A KE+ + V F+C+ + F W Sbjct: 11813 QLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRW 11872 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 K +EI+ D+RF++ G + +K+ ED Y D S +++ L+ Sbjct: 11873 LKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH-TSGKLIIEGIRLKF 11931 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 L PLK A E K F ++ H + ++ ND+ + + Sbjct: 11932 L-----------TPLKDVTAKE---KESAVFTVELSH--DNIRVKWFKNDQRLHTTRSVS 11975 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 ++ + T I SI++ V+ ++ + +A TVLE Sbjct: 11976 MQDEGKTHSI--TFKDLSIDDTSQIRVE----------AMGMSSEAKLTVLE-------- 12015 Query: 1124 FLRKQGPHFAEYLH-WDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETETLPNLER 1180 P+F L + E+ EV L C++ +K + KW KD ++ + + Sbjct: 12016 ----GDPYFTGKLQDYTGVEKDEVILQCEI--SKADAPVKWFKDGKEIKPSKNAVIKADG 12069 Query: 1181 GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV-YDDMILAMSRVCGKSASPLK 1239 L++ K K D G+Y D G D + +GK+ +D + + R PL Sbjct: 12070 KKRMLILKKALKSDIGQYTC----DCGTD----KTSGKLDIEDREIKLVR-------PLH 12114 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 + E + + D++ NW K A LQ + K++G Sbjct: 12115 SVEVMETETARFETEISEDDIHANWKLKGE----------------ALLQTPDCEIKEEG 12158 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE-KNRGRLIGGLPDV--VTI 1356 K + H LD +G +FQ + A + + R+IG L + VT+ Sbjct: 12159 KIHSLVL-----HNCRLDQTGG------VDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 12207 Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 G+T C + D V W+ + ++ S+ V + K ++T++ V ED+G+ Sbjct: 12208 TAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKV-VPRSEGKVHTLTLRDVKLEDAGEV 12265 Query: 1417 SINIKN 1422 + K+ Sbjct: 12266 QLTAKD 12271 Score = 48.5 bits (114), Expect = 5e-05 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D +TI G+ LT G P P+V WFK++ D+ + +K A IK S Sbjct: 16826 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRS- 16884 Query: 1412 DSGKYSINIKNKYGGEK 1428 DSGKY + ++N G K Sbjct: 16885 DSGKYCVVVENSTGSRK 16901 Score = 48.5 bits (114), Expect = 5e-05 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G++ + ++G P P + W K DQ++ + +K S+++K Sbjct: 22551 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFA-TSLSVKDAVRV 22609 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y + KN G + V V V Sbjct: 22610 DSGNYILKAKNVAGERSVTVNVKV 22633 Score = 48.5 bits (114), Expect = 5e-05 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 15/145 (10%) Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQA-FDEAFAEFQQFKAAAFAEKNRGRLIGGLP 1351 P K KY+F + ++++ G + + E+ AE + + + L L Sbjct: 29405 PDLKMGQKYSFRV--------AAVNVKGMSEYSESIAEIEPVERIEIPDLE---LADDLK 29453 Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 VTI G +L L +V G P P + W K Q I L+ + ++ Y + + V Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTES-YSLLIVDKVNRY 29510 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSVY 1436 D+GKY+I +N+ G + V V VY Sbjct: 29511 DAGKYTIEAENQSGKKSATVLVKVY 29535 Score = 48.1 bits (113), Expect = 6e-05 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V I EG L + GNP+P+++W KN I ++ +++E K ++ I S+D Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIP 1457 S Y+ NK G + V+V + A P+ + +IP Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVE------VEFAEPEPERKLIIP 1663 Score = 48.1 bits (113), Expect = 6e-05 Identities = 52/232 (22%), Positives = 86/232 (37%), Gaps = 38/232 (16%) Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 + P + + S V +V L T QG ++W+K + G I Sbjct: 4202 VQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNK---ELVSGGSCYITKEA 4258 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 +LE+ D+ TY+ +N G V +A + V+ EP Sbjct: 4259 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK------EP-------------- 4298 Query: 270 MIPYTHFDVQFLEKFGVT-FRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 F+EK + ++G+ L C + TP +K W+ +D +KES Sbjct: 4299 --------ATFVEKLEPSQLLKKGDATQLACKVTGTPPIK-----ITWFANDREIKESSK 4345 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT 380 +M F E A L + + +D G Y + G SDH + + + P T Sbjct: 4346 HRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG-SDHCSSIVIVKESPYFT 4396 Score = 48.1 bits (113), Expect = 6e-05 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L ++ I G +L L + G P PEV W K D +I+ + V + + S+ + V Sbjct: 22948 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT---SSFTSLVLDNVN 23004 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ ++N G + VTV V Sbjct: 23005 RYDSGKYTLTLENSSGTKSAFVTVRV 23030 Score = 47.8 bits (112), Expect = 8e-05 Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 37/222 (16%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W+KDG I A +YRI G +LEI R D +D ++ ATN+ G ++ A+ Sbjct: 4144 VSWFKDGKEI---AASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 4200 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 +V +EP F+ K G G V LK T + Sbjct: 4201 IV------QEP----------------------PSFVTKPGSKDVLPGSAVCLKSTFQGS 4232 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 L W++ + L + ++SL + D G YT ++ + G Sbjct: 4233 TPL-----TIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGV 4287 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPP 406 + SA LFV++ V + + L+ DA + VT PP Sbjct: 4288 ECSANLFVKEPATFVEKLEPSQL-LKKGDATQLACKVTGTPP 4328 Score = 47.4 bits (111), Expect = 1e-04 Identities = 91/436 (20%), Positives = 177/436 (40%), Gaps = 67/436 (15%) Query: 999 EELERLMALSNEIKNPTI-PLKSEL-----AYEIFDKGRVRFWLQAEHLSPDASYRFIIN 1052 EE ++ +A +I PT P K EL A +IF+ R Q DA +R + Sbjct: 2047 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFE----RIQSQTVGQGSDAHFRVRVV 2102 Query: 1053 DREVSDSEIHR--IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAF 1110 + + E ++ +K +++ I + + + I D A+ +S+++ Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIY------WYWPEDNVCELVIRDVTAEDSASIMV----- 2151 Query: 1111 KTVLEEAEFQRKEFLRKQGPH---FAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDD 1167 K + E FL Q F + L V +E + + ++ KW KD Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2211 Query: 1168 V-LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRG-QDVSILEIAGKVYDDMI 1224 + ++E + + +R + L I + D +Y L +D + + L + G V + + Sbjct: 2212 MEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV- 2270 Query: 1225 LAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEE 1284 K ++V + G L+C + + ++ W H D ++ S+ I Sbjct: 2271 --------KELQDIEVPESYSG-ELECIVS--PENIEGKWYHNDVELKSNGKYTITSRRG 2319 Query: 1285 MAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG 1344 L + + T++D+G+Y+F + DGK + + K A Sbjct: 2320 RQNLTVKDVTKEDQGEYSF-VIDGKKTTCK----------------LKMKPRPIA----- 2357 Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 ++ GL D + EG + L V E +W K+ Q++Q S+ + +++ ++ + Sbjct: 2358 -ILQGLSD-QKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHM-LL 2413 Query: 1405 IKGVTSEDSGKYSINI 1420 I+ +T ED+G YS I Sbjct: 2414 IEDMTKEDAGNYSFTI 2429 Score = 47.0 bits (110), Expect = 1e-04 Identities = 116/553 (20%), Positives = 198/553 (35%), Gaps = 103/553 (18%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS--VSVSDT 987 F+C + TW K I + + + G KL++ + D G Y+ + + + Sbjct: 11138 FECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 11197 Query: 988 DGVSSSFVLDPEELERLMALSNE----IKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 + S++ ++ E R + E +K + L EL +K R W + + Sbjct: 11198 EKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL-----NKERDVVWRKDGKIVV 11252 Query: 1044 DASYRFI-----------INDREVSDS--------EIHRIKCDKATGIIEMVMDRFSIEN 1084 + R + IND + +D+ + ++C ++E++ D Sbjct: 11253 EKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL---- 11308 Query: 1085 EGTYTVQIHDGKAKSQSSLVLIGDAFKTVLE----------EAEFQRKEFLRKQGPHF-- 1132 I D K + + + D K AE K + + G H Sbjct: 11309 ----VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYL 11364 Query: 1133 --AEYLHWDVTE---ECE-VRLVCKVANTKKET-VFKWLKDDVLYETET----------- 1174 + D+ E E E R K+ ++E + K ++D +YE E+ Sbjct: 11365 KIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD 11424 Query: 1175 LPNLERGICELLIPKLS---KKDHGEYKATL-KDDRGQDVSILEIAGKVYDDMILAMSRV 1230 +P + ELL P + K + G+ TL K Q +L A IL + + Sbjct: 11425 IPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEI 11484 Query: 1231 CGKSASPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL 1288 A PLK + PE R +C + T E V W I SS+ I + L Sbjct: 11485 ELDFAVPLKDVTVPERRQARFECVL---TREANVIWSKGPDIIKSSDKFDIIADGKKHIL 11541 Query: 1289 QICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIG 1348 I + D+G YT E+ E ++ A F R + + Sbjct: 11542 VINDSQFDDEGVYTAEV-----------------------EGKKTSARLFVTGIRLKFMS 11578 Query: 1349 GLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 L D T+ EG+T C + + V+WFKND + S + E K + +K V Sbjct: 11579 PLEDQ-TVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSE-GKTHKLEMKEV 11635 Query: 1409 TSEDSGKYSINIK 1421 T +D + +K Sbjct: 11636 TLDDISQIKAQVK 11648 Score = 47.0 bits (110), Expect = 1e-04 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+T+ G+T+ + V G P+P++ W K + + + + ++ V + IK Sbjct: 17916 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRA 17974 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY I+ KN G + V+V Sbjct: 17975 DHGKYIISAKNSSGHAQGSAIVNV 17998 Score = 47.0 bits (110), Expect = 1e-04 Identities = 48/209 (22%), Positives = 81/209 (38%), Gaps = 22/209 (10%) Query: 1238 LKVLCTPEGIRLQCFMKYFTDEMK-VNWCHKDAKISSSEHMRIGGSEEMAW-LQICEPTE 1295 LK + E +L C ++ K V W K+ + H + S + + L+I TE Sbjct: 32724 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 32783 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAF----------DEAFAEFQQFKAAAFAEKNRGR 1345 D+G+Y EI + +L GQAF E Q+ + K + Sbjct: 32784 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 32843 Query: 1346 L---IGGLPDVVTIMEGKTLN------LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE 1396 I P +VT ++ T++ G P P IW K+ + I + + + Sbjct: 32844 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSED 32903 Query: 1397 QAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + + I + DSG Y+ +KN G Sbjct: 32904 KGGFF-LEIHKTDTSDSGLYTCTVKNSAG 32931 Score = 46.6 bits (109), Expect = 2e-04 Identities = 100/499 (20%), Positives = 179/499 (35%), Gaps = 72/499 (14%) Query: 943 WCKSYEE-ISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS-SFVLDPEE 1000 W K E I + E +I + + + L L +P+ + G Y + + G+ S VL E Sbjct: 6584 WLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE 6643 Query: 1001 LERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSE 1060 R++ + T+ + A E G +P+ S ++ + RE+S Sbjct: 6644 PARIIEKPEPM---TVTTGNPFALECVVTG-----------TPELSAKWFKDGRELSADS 6689 Query: 1061 IHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQ 1120 H I +++ S ++G Y+ ++ + KS ++ +V Sbjct: 6690 KHHITFINKVASLKIPCAEMS--DKGLYSFEVKNSVGKSNCTV--------SVHVSDRIV 6739 Query: 1121 RKEFLRKQGPHFAEYLHWDVTE--ECEVRLVCKVANTKKETVFKWLKD--DVLYETETLP 1176 F+RK DV V L C+V+ + +V W +D +++ + Sbjct: 6740 PPSFIRKLK---------DVNAILGASVVLECRVSGSAPISV-GWFQDGNEIVSGPKCQS 6789 Query: 1177 NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSAS 1236 + +C L + L D G Y + G D +L + + Sbjct: 6790 SFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDEC----------SAVLTVQEPPSFEQT 6839 Query: 1237 PLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEK 1296 P V P + T KV W ++ E I + + L++ E Sbjct: 6840 PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPL 6899 Query: 1297 DKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTI 1356 + G Y+ + N S + F + A F + + A F+ + Sbjct: 6900 ESGDYSCLV----TNDAGSASCTTHLFVKEPATFVK-RLADFS----------------V 6938 Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 G + L T G P V W K++ I SE S+ + + K + I T ED +Y Sbjct: 6939 ETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTE-KSTILEILESTIEDYAQY 6997 Query: 1417 SINIKNKYGGEKIDVTVSV 1435 S I+N+ G + + VSV Sbjct: 6998 SCLIENEAGQDICEALVSV 7016 Score = 46.2 bits (108), Expect = 2e-04 Identities = 51/207 (24%), Positives = 77/207 (37%), Gaps = 36/207 (17%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +V L V+G V W K +I E GK ++ + GV L I Y+ Sbjct: 3940 TVTLQAAVRGSEPISVTWMKGQEVI---REDGKIKMSFSNGVAVLIIPDVQISFGGKYTC 3996 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 +A N G ++ ++V+ EP + +E+ + Sbjct: 3997 LAENEAGSQTSVGELIVK------EP----------------------AKIIERAELIQV 4028 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 G+ TL+ T+ TP+LK +WY+D L SK ++ F A L F D Sbjct: 4029 TAGDPATLEYTVAGTPELK-----PKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHD 4083 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDAD 376 G YT I + G S V D D Sbjct: 4084 SGQYTFEISNEVGSSSCETTFTVLDRD 4110 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 +LI GL + G T+ + G P P W + +I+ EH++V+ + V +T Sbjct: 17515 KLIEGL----VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LT 17569 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 IK D+G+Y I + N G + + V ++V Sbjct: 17570 IKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600 Score = 45.8 bits (107), Expect = 3e-04 Identities = 24/79 (30%), Positives = 39/79 (49%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 +EG+T V G P PE WF + Q I V +++ S+ I T DSG++ Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1528 Query: 1417 SINIKNKYGGEKIDVTVSV 1435 ++ +N+ G I V ++V Sbjct: 1529 TVVAQNRAGRSSISVILTV 1547 Score = 45.8 bits (107), Expect = 3e-04 Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 37/177 (20%) Query: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 P V+WYKDG + E KYR+ S+ VH L I D D YS V V T Sbjct: 2201 PFVKVKWYKDGM---EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKT 2256 Query: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 A ++V +++ + V+ L+ V GE L+C Sbjct: 2257 TAKLIVE--------------------GAVVEF----VKELQDIEVPESYSGE---LEC- 2288 Query: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRI 357 +V+P+ +WY +DV LK + + G+ +L+ + K+D+G Y+ I Sbjct: 2289 -IVSPE----NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI 2340 Score = 45.8 bits (107), Expect = 3e-04 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VV + TL L T+ G P+PEV W K + L++ ++V + + + I VT Sbjct: 25113 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEG--ILTDRAQIEV-TSSFTMLVIDNVT 25169 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSG+Y++ ++N G + V V V Sbjct: 25170 RFDSGRYNLTLENNSGSKTAFVNVRV 25195 Score = 45.4 bits (106), Expect = 4e-04 Identities = 55/259 (21%), Positives = 97/259 (37%), Gaps = 44/259 (16%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + +L + V+L T++G V W+KD I + E I + + T Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR--ESDNIWISYSENIAT 7549 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L+ +R + + Y+ N G A + V EP V P + +++ Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL------EPATIVEKPESIKVTT---- 7599 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 G+T TL+CT+ TP+L +W++D L K+ F Sbjct: 7600 ------------------GDTCTLECTVAGTPELS-----TKWFKDGKELTSDNKYKISF 7636 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRD--ADPLVT-------GAPG 384 + L ++ D G+Y+ + + G +A L V D P T G G Sbjct: 7637 FNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSG 7696 Query: 385 APMDLQCHDANRDYVIVTW 403 + + ++C + V+W Sbjct: 7697 SSVVMECKVYGSPPISVSW 7715 Score = 45.4 bits (106), Expect = 4e-04 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 I G TL L+ + G P P+V W K D+D V +K + I+ ED G Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 17286 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 YS+ ++N G + + V V V Sbjct: 17287 YSLTVENPAGSKTVSVKVLV 17306 Score = 45.1 bits (105), Expect = 5e-04 Identities = 91/479 (18%), Positives = 176/479 (36%), Gaps = 75/479 (15%) Query: 943 WCKSYEEISDDERFKIETVGDH-SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEEL 1001 W K+ +I +R D+ +L +++ ED + V + G +SS + Sbjct: 2111 WYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170 Query: 1002 ERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEI 1061 ++L+ + E+++ K +A + E P ++ + EV + + Sbjct: 2171 KQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGMEVHEGDK 2219 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +R+ D+ + ++ S + E V + D K+ + L++ G + V E + + Sbjct: 2220 YRMHSDRKVHFLSILTIDTS-DAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIE- 2277 Query: 1122 KEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--E 1179 V E L C V+ E KW +DV ++ + Sbjct: 2278 ------------------VPESYSGELECIVSPENIEG--KWYHNDVELKSNGKYTITSR 2317 Query: 1180 RGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLK 1239 RG L + ++K+D GEY + D + + + L+ +VC Sbjct: 2318 RGRQNLTVKDVTKEDQGEYSFVI-DGKKTTCKLKMKPRPIAILQGLSDQKVC-------- 2368 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 EG +Q +K + ++ W ++ S+ + I ++ L I + T++D G Sbjct: 2369 -----EGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAG 2423 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEG 1359 Y+F I +L LS ++ +I L D V ++EG Sbjct: 2424 NYSFTI--------PALGLSTSGRVSVYSV---------------DVITPLKD-VNVIEG 2459 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 L C V V W+ ND+ I+ + V+ K + I + D G Y + Sbjct: 2460 TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ-RLVINRTHASDEGPYKL 2517 Score = 45.1 bits (105), Expect = 5e-04 Identities = 21/84 (25%), Positives = 42/84 (50%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+T L + G P P+V+W K+ ++++ + + ++ +K Sbjct: 24715 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 24774 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + + N G + I +TV V Sbjct: 24775 DGGQYILKLSNVGGTKSIPITVKV 24798 Score = 44.7 bits (104), Expect = 7e-04 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V ++EG T + G P PEV WF++ Q I S V++ + +TI VT + Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74 Query: 1413 SGKYSINIKNKYG 1425 SG+YS+ N G Sbjct: 75 SGRYSLKATNGSG 87 Score = 44.7 bits (104), Expect = 7e-04 Identities = 52/229 (22%), Positives = 87/229 (37%), Gaps = 49/229 (21%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 + W KD I G Y++ TL + + D Y+ A+N G+ S +A + Sbjct: 7243 ITWAKDNREIRPG---GNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQL 7299 Query: 245 VVR---RFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTM 301 V+ RF EP R V ++ E +C + Sbjct: 7300 GVQEPPRFIKKLEPSRIV------------------------------KQDEFTRYECKI 7329 Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 +P++K + WY+D+ ++ES +M F + A L +L +D G YT + Sbjct: 7330 GGSPEIKVL-----WYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 7384 Query: 362 GVSDHSAFLFVRDADPLVTGAP-------GAPMDLQCHDANRDYVIVTW 403 G + S L V++ P+ P GA + L+C V+W Sbjct: 7385 GSASSSTSLKVKE-PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSW 7432 Score = 44.7 bits (104), Expect = 7e-04 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + I G++L + V G P P V WFK+ +I+ + + + S+ ++ T + Sbjct: 27966 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRD 28024 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 G Y++ KN G K ++ V V Sbjct: 28025 HRGVYTVEAKNASGSAKAEIKVKV 28048 Score = 44.3 bits (103), Expect = 9e-04 Identities = 74/326 (22%), Positives = 128/326 (39%), Gaps = 34/326 (10%) Query: 1130 PHFAEYLHWDV--TEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLE----RGIC 1183 P F + L V TE +L +VA ++ TV W K+++ E + N E Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITV-AWYKNNI--EIQPTSNCEITFKNNTL 8305 Query: 1184 ELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCT 1243 L + K D G Y + +D G + I K V + +P+ V Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKK-----PPVFDQHLTPVTV-SE 8359 Query: 1244 PEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTF 1303 E ++L C ++ ++ +++ W +I S+ + A L++ + + D G Y Sbjct: 8360 GEYVQLSCHVQG-SEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVC 8418 Query: 1304 EIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNR---GRLIG-GLPDVVTIMEG 1359 ++ +++G ++ + A A A K GRL P + ++E Sbjct: 8419 ----------KASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEK 8468 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQ-AKYVSMTIKGVTSEDSGKYSI 1418 T V G+P P V W K QL++ V + Q + I+ T DSG Y Sbjct: 8469 TTATFIAKVGGDPIPNVKWTKGKWR-QLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRC 8527 Query: 1419 NIKNKYG--GEKIDVTVSVYKHGEKI 1442 N++G +++ V K EKI Sbjct: 8528 VAFNEHGEIESNVNLQVDERKKQEKI 8553 Score = 44.3 bits (103), Expect = 9e-04 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G+T L V G P P + W + D++I+ S +K K + + +K Sbjct: 23633 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL-LIVKDAIRI 23691 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + N G + V V V Sbjct: 23692 DGGQYILRASNVAGSKSFPVNVKV 23715 Score = 43.9 bits (102), Expect = 0.001 Identities = 43/189 (22%), Positives = 74/189 (39%), Gaps = 33/189 (17%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 +W+KDG + + KY+I V L+I + D+ Y+ N G+ S A + Sbjct: 4611 KWFKDGQELTLGS---KYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN 4667 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTP 305 V L +IP + F +K +G + L+C + + Sbjct: 4668 V--------------------LDLIIPPS-----FTKKLKKMDSIKGSFIDLECIVAGSH 4702 Query: 306 DLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSD 365 + +W++DD + S+ K F + A L S L D G YT ++ G + Sbjct: 4703 PIS-----IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQ 4757 Query: 366 HSAFLFVRD 374 S L V++ Sbjct: 4758 CSGHLTVKE 4766 Score = 43.9 bits (102), Expect = 0.001 Identities = 52/218 (23%), Positives = 84/218 (38%), Gaps = 36/218 (16%) Query: 157 LVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEI 216 L RL H+V S+ L T G V W KDG I + K I + LEI Sbjct: 5989 LKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSE---KCNIVTTEKTCILEI 6045 Query: 217 NRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHF 276 + D YS N G+ A V EP PY Sbjct: 6046 LNSTKRDAGQYSCEIENEAGRDVCGALVSTL------EP----------------PYFVT 6083 Query: 277 DVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG 336 +++ LE G++V+L+C + TP++ WY+ D L+ + + +F Sbjct: 6084 ELEPLEA------AVGDSVSLQCQVAGTPEIT-----VSWYKGDTKLRPTPEYRTYFTNN 6132 Query: 337 QASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRD 374 A+L F+ ++ +D G YT + + G + +++ Sbjct: 6133 VATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQE 6170 Score = 43.9 bits (102), Expect = 0.001 Identities = 52/265 (19%), Positives = 99/265 (37%), Gaps = 32/265 (12%) Query: 1183 CELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLC 1242 C L + L + D G+Y + G D + + + + P+ VL Sbjct: 7737 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV--------QKPDPMDVL- 7787 Query: 1243 TPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYT 1302 T + +K T V+W +++ + + + +A L++ + G+YT Sbjct: 7788 TGTNVTFTSIVKG-TPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT 7846 Query: 1303 FEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTL 1362 + S +A + KA A + + L D +I +GK L Sbjct: 7847 CIV-------------SNEAGKASCTTHLYIKAPA-------KFVKRLNDY-SIEKGKPL 7885 Query: 1363 NLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKN 1422 L T G P V W KN ++ S+ ++ + K + I T ED+G+Y+ I+N Sbjct: 7886 ILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTE-KSAILEIPSSTVEDAGQYNCYIEN 7944 Query: 1423 KYGGEKIDVTVSVYKHGEKIPDMAP 1447 G + + + + + + P Sbjct: 7945 ASGKDSCSAQILILEPPYFVKQLEP 7969 Score = 43.9 bits (102), Expect = 0.001 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E SV V G P P ++W KDG + + P I + L I +DT Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDYYALHIRDTLPEDTGY 31865 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRS 258 Y ATN G S A + V R R ++ F+S Sbjct: 31866 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKS 31897 Score = 43.5 bits (101), Expect = 0.001 Identities = 60/266 (22%), Positives = 105/266 (39%), Gaps = 54/266 (20%) Query: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238 G PT VV+W DG + A + R+ + +G +L+ A D+ + ATN +G Sbjct: 1730 GDPTMVVEWLHDGKPLEAA---NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTD 1786 Query: 239 STNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF----------GVTF 288 T+A ++V+ DE+ L S +P +Q +E+ GVT Sbjct: 1787 HTSATLIVK----DEK---------SLVEESQLPEGRKGLQRIEELERMAHEGALTGVTT 1833 Query: 289 RR------------------EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 + EGET +C + P QP+ WY + L+++SK + Sbjct: 1834 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFR 1888 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR---DADPLVTGAPGAPM 387 + + +G L D G + + GV +H L ++ D ++ AP Sbjct: 1889 VRY-DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1947 Query: 388 DLQCHDANR-DYVIVTWKPPNTTTES 412 + H+ + + + P TTE+ Sbjct: 1948 EFHVHEPGKLQFEVQKVDRPVDTTET 1973 Score = 43.5 bits (101), Expect = 0.001 Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 8/141 (5%) Query: 107 ELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVW 166 EL H +++ +A + K I DK+ AP+I R++S TV Sbjct: 2037 ELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSM------EAPKIFERIQSQTVG 2090 Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 + V G P P +WYK+G I ++ Y E N V L I +D+A+ Sbjct: 2091 QGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN--VCELVIRDVTAEDSAS 2148 Query: 227 YSAVATNAHGQVSTNAAVVVR 247 A N G+ S++A ++V+ Sbjct: 2149 IMVKAINIAGETSSHAFLLVQ 2169 Score = 43.5 bits (101), Expect = 0.001 Identities = 61/311 (19%), Positives = 116/311 (37%), Gaps = 47/311 (15%) Query: 102 QRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLR 161 ++F H + +H+ +A D + +Y + E + + + + P + +L Sbjct: 6502 KKFKITSKHFDTSLHILNLEASD-VGEYHCKATNE--VGSDTCSCSVKFKEPPRFVKKLS 6558 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221 + +V+L V+GF V W KD + + +E + N + TL++ + Sbjct: 6559 DTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDN--IATLQLGSPEA 6616 Query: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281 ++ Y N G +A + V EP R + P + +++ P+ Sbjct: 6617 SNSGKYICQIKNDAGMRECSAVLTVL------EPARIIEKPEPMTVTTGNPFA------- 6663 Query: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341 L+C + TP+L A+W++D L + F ASL Sbjct: 6664 ---------------LECVVTGTPELS-----AKWFKDGRELSADSKHHITFINKVASLK 6703 Query: 342 FSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRD--ADPL-------VTGAPGAPMDLQCH 392 D+GLY+ + + G S+ + + V D P V GA + L+C Sbjct: 6704 IPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECR 6763 Query: 393 DANRDYVIVTW 403 + + V W Sbjct: 6764 VSGSAPISVGW 6774 Score = 43.5 bits (101), Expect = 0.001 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G + +T G P P V+W K D D++ + + S+TI+ DSGK Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRT---SLTIENANRNDSGK 26254 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ I+N + + V V Sbjct: 26255 YTLTIQNVLSAASLTLVVKV 26274 Score = 43.1 bits (100), Expect = 0.002 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM-FFGEGQASLSFSHLHKDD 349 EG VT C M P P+ WY+D +K + +M F +G+ASL + +D Sbjct: 1304 EGMGVTFHCKMSGYP-----LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAP 383 EG+YT + G + S L+V A PL GAP Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYVEPAAPL--GAP 1390 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%) Query: 145 TFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR 204 T +++ + P+I++ V E + + V G+P P V WY +G LI ++ ++R Sbjct: 1832 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK---RFR 1888 Query: 205 IESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSV 259 + + G+H L+I DT A N G + + +++ E FRSV Sbjct: 1889 VRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ----REDFRSV 1938 Score = 43.1 bits (100), Expect = 0.002 Identities = 80/376 (21%), Positives = 138/376 (36%), Gaps = 82/376 (21%) Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 VL E TK + A ++ + C+ ++ W K EEI + R++I T G Sbjct: 12458 VLEEEAVFTKNL-ANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 12516 Query: 965 SKLYLKNPDKEDLGTYSVSV--SDTDG------VSSSFVLDPEELERLMALSNE----IK 1012 L ++N ED G Y+ + S TDG +++ F+ P+ LE L E I Sbjct: 12517 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 12576 Query: 1013 NPTIP---------LKSELAYEIFDKGRVRFWL--------------------QAEHLSP 1043 + P L+S Y++ G+ R + A HL+ Sbjct: 12577 KESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV 12636 Query: 1044 DASYRFII--NDREVSDSEIHRIKCDKATGII--------EMVMDR---FSIENEGTYTV 1090 R ++ D V + + C+ T E + D ++ + YT+ Sbjct: 12637 IEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTL 12696 Query: 1091 QIHDGKAKSQSSLVL---------IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVT 1141 +I D Q++ + + A ++EE + + E L+ + Sbjct: 12697 RIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLK----------DIETM 12746 Query: 1142 EECEVRLVCKVANTKKETVFKWLK--DDVLYETETLPNLERGICELLIPKLSKKDHGEYK 1199 E+ V CKV + KW K ++V ++ +++ L I D GEY Sbjct: 12747 EKKSVTFWCKV--NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI 12804 Query: 1200 ATLKDDRGQDVSILEI 1215 T GQD S+ E+ Sbjct: 12805 VT----AGQDKSVAEL 12816 Score = 43.1 bits (100), Expect = 0.002 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G ++ L G P P +W K D ++ L + ++T++ D+GK Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 28425 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ ++N G + I TV V Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445 Score = 42.7 bits (99), Expect = 0.003 Identities = 42/190 (22%), Positives = 75/190 (39%), Gaps = 33/190 (17%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V WYKDG + + +++ TL I + D YS ATN G S++A + Sbjct: 8088 VSWYKDGKPLKDSPNVQTSFLDNTA---TLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 ++ G PF + L P+ +++ GE+ +C + T Sbjct: 8145 ILTE--GKNPPFFDIRLA---PVDAVV--------------------GESADFECHVTGT 8179 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 +K W +D ++ ++ + E A L+ + K D G YT V+ G Sbjct: 8180 QPIK-----VSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKD 8234 Query: 365 DHSAFLFVRD 374 +A L +++ Sbjct: 8235 SCTAQLNIKE 8244 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE-QAKYVSMTIKGV 1408 L V+T+ G T+ L V G P PEV W K+ L+ VK++ +A ++ Sbjct: 18207 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 18266 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY + N G TV+V Sbjct: 18267 KRSDGGKYVVTATNTAGSFVAYATVNV 18293 Score = 42.7 bits (99), Expect = 0.003 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + ++T+ G + L TVFG P P V W K+ ++ +E + + Q ++ + V Sbjct: 19301 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVN 19359 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 +DSG Y+I +N G + + + V Sbjct: 19360 RKDSGDYTITAENSSGSKSATIKLKV 19385 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 V + G+ +++ G PDP + W K I + H+ V V ++ + GV +D+ Sbjct: 31037 VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDA 31096 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 G Y + KN++G ++ V + V +PD PP+ K Sbjct: 31097 GFYVVCAKNRFGIDQKTVELDV----ADVPD--PPRGVK 31129 Score = 42.4 bits (98), Expect = 0.003 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 42/226 (18%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W+ + + I A KY+ + V TL++N D D Y+ VA N G A + Sbjct: 5831 VAWFHEKTKIVSGA---KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 5887 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 V +EP V P L ++P G+ VT + T Sbjct: 5888 TV------QEPPSFVKEPEPL---EVLP-------------------GKNVTFTSVIRGT 5919 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P K W+R L + ++F + A L ++ G YT + + G + Sbjct: 5920 PPFK-----VNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQA 5974 Query: 365 DHSAFLFVRDADPLV------TGAPGAPMDLQCHDANRDYVIVTWK 404 + LFV++ + + PG + L+ + VTWK Sbjct: 5975 SCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWK 6020 Score = 42.4 bits (98), Expect = 0.003 Identities = 54/227 (23%), Positives = 87/227 (38%), Gaps = 45/227 (19%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 + W KD I G Y I L I + D+ Y+ ATN G+ +A + Sbjct: 6302 ITWSKDNKEIRPG---GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVT-FRREGETVTLKCTMLV 303 V+ E P +F++K + ++GE++ L+C + Sbjct: 6359 SVK-----EPP-----------------------KFVKKLEASKVAKQGESIQLECKISG 6390 Query: 304 TPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGV 363 +P++K W+R+D L ES M F A L+ + +D G Y + G Sbjct: 6391 SPEIK-----VSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGD 6445 Query: 364 SDHSAFLFVRDADPLVTGAP-------GAPMDLQCHDANRDYVIVTW 403 + S L V+ A P+ T P G+ + LQC + V W Sbjct: 6446 ASCSTALTVK-APPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVW 6491 Score = 42.4 bits (98), Expect = 0.003 Identities = 57/257 (22%), Positives = 91/257 (35%), Gaps = 37/257 (14%) Query: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235 TV G P +W+KDG + KY+I V L+I D+ YS N Sbjct: 7608 TVAGTPELSTKWFKDGK---ELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPV 7664 Query: 236 GQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETV 295 G+ S A++ V +P + F K T G +V Sbjct: 7665 GKDSCTASLQVS--------------------DRTVPPS-----FTRKLKETNGLSGSSV 7699 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTL 355 ++C + +P + W+ + + + + + +L+ + L + D G YT Sbjct: 7700 VMECKVYGSPPIS-----VSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTC 7754 Query: 356 RIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 + G + SA L VR+ V PMD+ IV PP + + Sbjct: 7755 IATNMAGSDECSAPLTVREPPSFVQKPD--PMDVLTGTNVTFTSIVKGTPPFSVSWFKGS 7812 Query: 416 GYFV--DRCEVGTNNWV 430 V DRC V + V Sbjct: 7813 SELVPGDRCNVSLEDSV 7829 Score = 42.4 bits (98), Expect = 0.003 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+ L + + G P P + W K+ +I+ + + + +T+K Sbjct: 25797 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRR 25855 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D+G+Y + +KN G + V V Sbjct: 25856 DTGQYVLTLKNVAGTRSVAVNCKV 25879 Score = 42.0 bits (97), Expect = 0.004 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKN----DQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + IM GKTL + V G P P +W K D+D + ++ K E + IK Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 15167 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 +D G+Y I N G + V V+ + D+ P Sbjct: 15168 RKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKP 15205 Score = 42.0 bits (97), Expect = 0.004 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 1350 LPDVVTIMEGKTLNLTC-TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 + D +TI G T+ L ++ G P P+ W K +DI+ S+ + + +TIK Sbjct: 20384 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYA 20442 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 T +D+G+Y+I N +G + V V+V Sbjct: 20443 TRKDAGEYTITATNPFGTKVEHVKVTV 20469 Score = 42.0 bits (97), Expect = 0.004 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G+ + L + G P P WF ++ SE +V+ K +TI+ T D+ Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH-TKVAKLTIRETTIRDT 29806 Query: 1414 GKYSINIKNKYG 1425 G+Y++ +KN G Sbjct: 29807 GEYTLELKNVTG 29818 Score = 41.6 bits (96), Expect = 0.006 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Query: 1349 GLPDVVTIM-EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 GLPD+ + E L + G P P V W K + + SV+ A ++ + Sbjct: 19986 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYD 20044 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+GKY+I +KN G ++ +++ V Sbjct: 20045 CQKSDAGKYTITLKNVAGTKEGTISIKV 20072 Score = 41.6 bits (96), Expect = 0.006 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VVTI TL L + G P PEV W ++ + + S++ + Y + + V Sbjct: 21866 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHG--ESLDKASIE-STSSYTLLIVGNVN 21922 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 DSGKY + ++N G + V V V + PPQ K K Sbjct: 21923 RFDSGKYILTVENSSGSKSAFVNVRV------LDTPGPPQDLKVK 21961 Score = 41.6 bits (96), Expect = 0.006 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 +VV G ++ L + G P P + W+K+D+++Q + V+ S+ IK Sbjct: 26880 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 26938 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 +SG Y + ++N G + V + Sbjct: 26939 NSGCYELKLRNAMGSASATIRVQI 26962 Score = 41.2 bits (95), Expect = 0.007 Identities = 118/574 (20%), Positives = 203/574 (35%), Gaps = 100/574 (17%) Query: 892 ANGVGKPSDTSEPVLVEARPGT-----KEISAGVDEQGNIYLGFDCQEM-TDASQFTWCK 945 +N G S T+ + EA P T K ++ V + F C T + W K Sbjct: 3531 SNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAK----FICTVTGTPVIETIWQK 3586 Query: 946 SYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGV----SSSFVLD-PEE 1000 +S ++I + L L N +D G YS S+ G + ++D P Sbjct: 3587 DGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHF 3646 Query: 1001 LERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSE 1060 ++ L + + I N + L+ ++ + K V + + L P Y+ D+ ++ E Sbjct: 3647 IKELEPVQSAI-NKKVHLECQVDED--RKVTVTWSKDGQKLPPGKDYKICFEDK-IATLE 3702 Query: 1061 IHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQ 1120 I K +++ GTY + S S + TV E F Sbjct: 3703 IPLAK----------------LKDSGTYVCTASNEAGSSSCSATV------TVREPPSFV 3740 Query: 1121 RK---EFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN 1177 +K +L G RL CK+ + V + + L E+ T+ Sbjct: 3741 KKVDPSYLMLPGE--------------SARLHCKLKGSPVIQVTWFKNNKELSESNTVRM 3786 Query: 1178 LERGICELL-IPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSAS 1236 +L I + +D G Y +D G D EI K I K+ Sbjct: 3787 YFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI--------KTLE 3838 Query: 1237 PLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEK 1296 P ++ + LQC + T +++W +I SS+ R+ + + L+I Sbjct: 3839 PADIVRGTNAL-LQCEVSG-TGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSA 3896 Query: 1297 DKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE---KNRGRLIGGLPDV 1353 D G+Y E + K A K + + D+ Sbjct: 3897 DVGEY-----------------------ECVVANEVGKCGCMATHLLKEPPTFVKKVDDL 3933 Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSED 1412 + + G+T+ L V G+ V W K + I+ E +K+ + V+ + I V Sbjct: 3934 IA-LGGQTVTLQAAVRGSEPISVTWMKGQEVIR--EDGKIKMSFSNGVAVLIIPDVQISF 3990 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA 1446 GKY+ +N+ G + V + K KI + A Sbjct: 3991 GGKYTCLAENE-AGSQTSVGELIVKEPAKIIERA 4023 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L G ++T G + + G P P+V W + ++ ++ S+ + + ++T+ Sbjct: 28649 LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDR-TTLTV 28707 Query: 1406 KGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 K DSG+Y + ++N G + VTV V Sbjct: 28708 KDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737 Score = 40.8 bits (94), Expect = 0.010 Identities = 99/513 (19%), Positives = 182/513 (35%), Gaps = 69/513 (13%) Query: 940 QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPE 999 Q W + + DDE + V + + L + D G YS S S+ G +SS Sbjct: 6205 QVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA---- 6260 Query: 1000 ELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059 RL A + K+P +K ++ ++ F P + +++E+ Sbjct: 6261 ---RLTAREPK-KSPFFDIKP-VSIDVIAGESADFECHVTGAQP-MRITWSKDNKEIRPG 6314 Query: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119 + I C T + ++ + + G YT Q + K S L +V E +F Sbjct: 6315 GNYTITCVGNTPHLRIL--KVGKGDSGQYTCQATNDVGKDMCSAQL------SVKEPPKF 6366 Query: 1120 QRK---EFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYET-ETL 1175 +K + KQG ++L CK++ + + V + D L+E+ + Sbjct: 6367 VKKLEASKVAKQGE--------------SIQLECKISGSPEIKVSWFRNDSELHESWKYN 6412 Query: 1176 PNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSA 1235 + + L I + S +D G+Y + G + K S V Sbjct: 6413 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKG 6472 Query: 1236 SPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTE 1295 S + + C G T +V W ++ +S+ +I L I Sbjct: 6473 SDVILQCEISG----------TPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEA 6522 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVT 1355 D G+Y H ++ + G +F K R + L D T Sbjct: 6523 SDVGEY----------HCKATNEVGSDTCSCSVKF----------KEPPRFVKKLSDTST 6562 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSEDSG 1414 ++ G + L V G V+W K+ ++ + E + ++ ++ + + + +SG Sbjct: 6563 LI-GDAVELRAIVEGFQPISVVWLKDRGEV-IRESENTRISFIDNIATLQLGSPEASNSG 6620 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 KY IKN G + ++V + I P Sbjct: 6621 KYICQIKNDAGMRECSAVLTVLEPARIIEKPEP 6653 Score = 40.8 bits (94), Expect = 0.010 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%) Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 W+ EP + K + T + +GK R L+ Q + ++ +A E L Sbjct: 13634 WVACGEPVAETKMEVT-GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 13692 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIK 1406 L +T+ G + L TV G P+P++ W K D ++ + +++ K ++TI Sbjct: 13693 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIV 13751 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+G Y I N G V V+V Sbjct: 13752 DSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780 Score = 40.4 bits (93), Expect = 0.013 Identities = 68/297 (22%), Positives = 116/297 (39%), Gaps = 49/297 (16%) Query: 1150 CKVANTKKETVFKWLKDDVL----YETETLPNLERGICELLIPKLSKKDHGEYKATLKDD 1205 C+V K V+ W K V Y + N + G C+L+I D GEY +++ Sbjct: 1103 CQVGGNPKPHVY-WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNK 1161 Query: 1206 RGQ---DVSILEIAG-----KVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFT 1257 G+ S+LE A K +M L ++V P KV T G + K + Sbjct: 1162 HGETSASASLLEEADYELLMKSQQEM-LYQTQVTAFVQEP-KVGETAPGFVYSEYEKEYE 1219 Query: 1258 DEMKV--NWCHKDAKISSS----EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDN 1311 E + KD + + + I EE ++ + E K T E +D Sbjct: 1220 KEQALIRKKMAKDTVVVRTYVEDQEFHISSFEE----RLIKEIEYRIIKTTLEELLEEDG 1275 Query: 1312 HQR-SLDLS-GQAFDEAF-AEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTV 1368 ++ ++D+S +A + F + + ++ I+EG + C + Sbjct: 1276 EEKMAVDISESEAVESGFDSRIKNYR---------------------ILEGMGVTFHCKM 1314 Query: 1369 FGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 G P P++ W+K+ + I+ E + + Q S+ I V ED G Y+ N G Sbjct: 1315 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1371 Score = 40.4 bits (93), Expect = 0.013 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 11/109 (10%) Query: 159 RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE-SNYGVHTLEIN 217 R++++ + E M V + G+P P + WYKDG I +Y+++ G +L I Sbjct: 1296 RIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE---RYQMDFLQDGRASLRIP 1352 Query: 218 RADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +D Y+A A+N G + + V EP +G P +P Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYV-------EPAAPLGAPTYIP 1394 Score = 40.4 bits (93), Expect = 0.013 Identities = 21/71 (29%), Positives = 32/71 (45%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ +G + V G PDPE W+KN I+ S+ + + I+ VT+EDS Sbjct: 2088 TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2147 Query: 1415 KYSINIKNKYG 1425 + N G Sbjct: 2148 SIMVKAINIAG 2158 Score = 40.4 bits (93), Expect = 0.013 Identities = 56/241 (23%), Positives = 90/241 (37%), Gaps = 45/241 (18%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 V L + G P V WYKD Q KY+I S ++ I D D Y Sbjct: 5534 VSLECELSGTPPFEVVWYKDKR---QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCK 5590 Query: 231 ATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR 290 A N G + V ++ EP R F+ K Sbjct: 5591 AQNEVGSDTCVCTVKLK------EPPR----------------------FVSKLNSLTVV 5622 Query: 291 EGETVTLKCTMLVTPDLKRVQPR-AEWYRD-DVLLKESKWTKMFFGEGQASLSFSHLHKD 348 GE L+ + ++ QP +W ++ + +++ES+ ++ F E A+L F+ Sbjct: 5623 AGEPAELQAS------IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPA 5676 Query: 349 DEGLYTLRIVSRGGVSDHSAFLFVRDADPLV------TGAPGAPMDLQCHDANRDYVIVT 402 + G Y +I + GG+ ++ A L V + +V T G L+C A + V Sbjct: 5677 NAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVE 5736 Query: 403 W 403 W Sbjct: 5737 W 5737 Score = 40.4 bits (93), Expect = 0.013 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 18/121 (14%) Query: 1332 QFKAAAFAEKNRG--RLIG--------------GLP-DVVTIMEGKTLNLTCTVFGNPDP 1374 QF+ A+ EK + R++G LP + +I G+ L + V G P P Sbjct: 24282 QFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRP 24341 Query: 1375 EVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 + W K+ + ++ + +V+ E A + IK +D GKY++ N G +++V Sbjct: 24342 NISWVKDGEPLKQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 24400 Query: 1435 V 1435 V Sbjct: 24401 V 24401 Score = 40.0 bits (92), Expect = 0.017 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + ++EG+ L++ P P V W K+ ++++ S+ ++K + K V + D+ Sbjct: 14396 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DA 14454 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y+I ++NK G + V V Sbjct: 14455 GIYTITLENKLGSATASINVKV 14476 Score = 40.0 bits (92), Expect = 0.017 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1344 GRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY-VS 1402 G L L + + G T+ L V G P P++ W K ++ L + + ++ + Sbjct: 19693 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSK--PNVNLRDRIGLDIKSTDFDTF 19750 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 + + V D+GKY + ++N G ++ + V V Sbjct: 19751 LRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783 Score = 40.0 bits (92), Expect = 0.017 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ + + G P P V W K+++++ +S++ + + +TI VT D+GKY + Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKYIL 27344 Query: 1419 NIKNKYGGEKIDVTVSV 1435 I+N G K TVSV Sbjct: 27345 TIENGVGEPK-SSTVSV 27360 Score = 39.7 bits (91), Expect = 0.022 Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ EG+T +TC F P+ + WF+N + ++ +VE K +TI V +ED Sbjct: 8754 VTLKEGQTCTMTCQ-FSVPNVKSEWFRNGRILKPQGRHKTEVEH-KVHKLTIADVRAEDQ 8811 Query: 1414 GKYS 1417 G+Y+ Sbjct: 8812 GQYT 8815 Score = 39.7 bits (91), Expect = 0.022 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 27/191 (14%) Query: 1263 NWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQA 1322 +W A + S ++ GGS+ ++ K++GK +E GKD R L Sbjct: 16431 DWTKSSADLEWSPPLKDGGSKVTGYIV----EYKEEGKEEWE--KGKDKEVRGTKLVVTG 16484 Query: 1323 FDE-AFAEFQ--QFKAAAFAEKN--------RGRLIG-------GLPDVVTIMEGKTLNL 1364 E AF +F+ A E + RL+ + D + + G + + Sbjct: 16485 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRI 16544 Query: 1365 TCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKY 1424 V G P P V W N++ L + +++ A SM IK G YS+ KN+ Sbjct: 16545 IAYVSGKPPPTVTWNMNER--TLPQEATIET-TAISSSMVIKNCQRSHQGVYSLLAKNEA 16601 Query: 1425 GGEKIDVTVSV 1435 G K + V V Sbjct: 16602 GERKKTIIVDV 16612 Score = 39.3 bits (90), Expect = 0.028 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 15/110 (13%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ EG+ + L+C V G+ + W K ++I+ S+ S V + ++ V DS Sbjct: 8355 VTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAV-LELRDVAKADS 8413 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASASAA 1463 G Y N G + V++ + KP + PA+ AA Sbjct: 8414 GDYVCKASNVAGSDTTKSKVTI--------------KDKPAVAPATKKAA 8449 Score = 39.3 bits (90), Expect = 0.028 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + +G + LT + G P P W K QDI S+ + + + + IK DS Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSET-HTELVIKEADRGDS 30202 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y + ++NK G + + + V V Sbjct: 30203 GTYDLVLENKCGKKAVYIKVRV 30224 Score = 39.3 bits (90), Expect = 0.028 Identities = 60/321 (18%), Positives = 118/321 (36%), Gaps = 50/321 (15%) Query: 68 CRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKL- 126 C++ K + ++ E Q+ ++ S + +A Q +S+ A E++ ++ +++++KL Sbjct: 32937 CKLTIKAI--KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLA 32994 Query: 127 -----DKYAIQQMMEDKLAW--ERHTFEERISRAPEILVRLRSHTVWERMSV-------- 171 K I + ++ A E+ E I++ + +R+H + S Sbjct: 32995 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQ 33054 Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 +L V+W +G + + E YR + TL I +A D + ++ Sbjct: 33055 RLVLKANIAGATDVKWVLNGVELTNSEE---YRYGVSGSDQTLTIKQASHRDEGILTCIS 33111 Query: 232 TNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRRE 291 G V + + + D F I P S I E Sbjct: 33112 KTKEGIVKCQYDLTLSKELSDAPAF------ISQPRSQNI------------------NE 33147 Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 G+ V C + P P EW+++++ + S + SL + D G Sbjct: 33148 GQNVLFTCEISGEPS-----PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 33202 Query: 352 LYTLRIVSRGGVSDHSAFLFV 372 YT++ + G +A L V Sbjct: 33203 KYTIKAKNFRGQCSATASLMV 33223 Score = 38.9 bits (89), Expect = 0.037 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK---YVSMTIKGVTS 1410 + + G + + G P PE+ W + + + F+ KV+ K Y ++I Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGE------FTDKVQIEKGVNYTQLSIDNCDR 24087 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 D+GKY + ++N G + VTV V + PPQ K Sbjct: 24088 NDAGKYILKLENSSGSKSAFVTVKV------LDTPGPPQNLAVK 24125 Score = 38.5 bits (88), Expect = 0.048 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ G ++L G P P + W K+ ++ SE + K ++++IK E Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK-ITLSIKNAKKEHG 27631 Query: 1414 GKYSINIKNKYGGEKIDVTV 1433 GKY++ + N + +TV Sbjct: 27632 GKYTVILDNAVCRIAVPITV 27651 Score = 38.5 bits (88), Expect = 0.048 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-DSGKYS 1417 G TL L G P P + WF + +Q SE+ +++ Y + +K V + +GKY Sbjct: 30643 GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE-NTEHYTHLVMKNVQRKTHAGKYK 30701 Query: 1418 INIKNKYG 1425 + + N +G Sbjct: 30702 VQLSNVFG 30709 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQL-SEHFSVKVEQAK----YVSMTIK 1406 D + + G+ +++ V G P P++ W KN+ I+ ++ + E+ ++I Sbjct: 15406 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 15465 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSVY 1436 ED G Y++ N+ G +V V VY Sbjct: 15466 KAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D V + G+ L V G P P + W K+ ++++ + +K+ ++ K T Sbjct: 21469 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS-TNLVNKDSTRR 21527 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y++ N G K V V Sbjct: 21528 DSGAYTLTATNPGGFAKHIFNVKV 21551 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSEDS 1413 T++ G+ L + G P P V W K+ ++ L + V E + S +TIK ED Sbjct: 22158 TVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKDACREDV 22215 Query: 1414 GKYSINIKNKYG 1425 G Y + + N G Sbjct: 22216 GHYVVKLTNSAG 22227 Score = 37.0 bits (84), Expect = 0.14 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V + G + L V G P P+V W K D + + V+ + + I T +D Sbjct: 18615 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF--LVIPNSTRDD 18672 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDM 1445 SGKYS+ + N G + + V V V + D+ Sbjct: 18673 SGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 18705 Score = 37.0 bits (84), Expect = 0.14 Identities = 16/79 (20%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 ++ G+ L + + G P P + W K+ ++ + +V + +++IK +D G Sbjct: 23240 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGG 23298 Query: 1415 KYSINIKNKYGGEKIDVTV 1433 +Y I + N G + + + Sbjct: 23299 QYGITVANVVGQKTASIEI 23317 Score = 37.0 bits (84), Expect = 0.14 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 907 VEARPGTKEISAGVDEQGNIYLGFDC--QEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 +E P + +I V E+G ++ + C + ++Q TW ++ + E+++I Sbjct: 31565 IEIGPVSGQIMHAVGEEGG-HVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV 31623 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSF 994 + LY+K+ K D GTY V + G SS+ Sbjct: 31624 AILYVKDITKLDDGTYRCKVVNDYGEDSSY 31653 Score = 36.6 bits (83), Expect = 0.18 Identities = 110/564 (19%), Positives = 213/564 (37%), Gaps = 96/564 (17%) Query: 879 QGKTYVFRVRAVNANGVGKP-------SDTSEPVLVEARP--GTKEISAGVDEQGNIYLG 929 +GKT+ ++ V + + + S T++ ++EA P K E+ I L Sbjct: 11624 EGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITL- 11682 Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 C+ D W K EEI ++ I+ G L +K D +D G Y V TD Sbjct: 11683 -KCEVSKDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY-VCDCGTDK 11739 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 ++ ++ RL+ + + + + +EI E PD ++ Sbjct: 11740 TKANVTVEA----RLIKVEKPLYGVEVFVGETAHFEI------------ELSEPDVHGQW 11783 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + + ++ S I D I+ ++ + G + Q + K+ + + + Sbjct: 11784 KLKGQPLTASPDCEIIEDGKKHIL--ILHNCQLGMTGEVSFQAANAKSAANLKVKELPLI 11841 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVL 1169 F T L + + V E+ E + C+V+ K F+WLK Sbjct: 11842 FITPLSDVK---------------------VFEKDEAKFECEVSREPK--TFRWLKG--- 11875 Query: 1170 YETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS--ILEIAGKVYDDMILAM 1227 T+ + +R EL+ KD ++ +K +D + + E K + L + Sbjct: 11876 --TQEITGDDR--FELI------KDGTKHSMVIKSAAFEDEAKYMFEAEDK-HTSGKLII 11924 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAW 1287 + K +PLK + E ++ D ++V W D ++ ++ + + Sbjct: 11925 EGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSM-------- 11976 Query: 1288 LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLI 1347 +D+GK F KD S+D + Q EA + K + Sbjct: 11977 --------QDEGKTHSITF--KD---LSIDDTSQIRVEAMGMSSEAKLTVL--EGDPYFT 12021 Query: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 G L D + + + + L C + D V WFK+ ++I+ S++ +K + K + + +K Sbjct: 12022 GKLQDYTGVEKDEVI-LQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADGKKRM-LILKK 12078 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDV 1431 D G+Y+ + K+D+ Sbjct: 12079 ALKSDIGQYTCDCGTDKTSGKLDI 12102 Score = 36.6 bits (83), Expect = 0.18 Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 24/144 (16%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 +W+++ I ++ KY I V+TL I A DD A Y+ TN G+ +AA + Sbjct: 12671 KWFRNEEAIFDSS---KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANL 12727 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF--RREGETVTLKCTM-- 301 + +EE R V PL D++ +EK VTF + VTLK T Sbjct: 12728 I----VEEEDLRIVE-----PLK--------DIETMEKKSVTFWCKVNRLNVTLKWTKNG 12770 Query: 302 LVTPDLKRVQPRAEWYRDDVLLKE 325 P RV R + Y+ + +K+ Sbjct: 12771 EEVPFDNRVSYRVDKYKHMLTIKD 12794 Score = 36.6 bits (83), Expect = 0.18 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 1370 GNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEK 1428 G P V W K+ Q L E V V +K V S++IK + ED G Y + + N G Sbjct: 25420 GRPQATVNWRKDGQT--LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 25477 Query: 1429 IDVTVSV 1435 + +T+ V Sbjct: 25478 VPITIIV 25484 Score = 36.6 bits (83), Expect = 0.18 Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK--YVSMTIKGVTSEDSGKYSINIK 1421 L C V G+P P V W++ ++I +++ ++++ K Y + I VT +D+ Y + Sbjct: 30947 LVCKVTGHPKPIVKWYRQGKEI-IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRAT 31005 Query: 1422 NKYG 1425 N+ G Sbjct: 31006 NQGG 31009 Score = 36.2 bits (82), Expect = 0.24 Identities = 49/261 (18%), Positives = 95/261 (36%), Gaps = 43/261 (16%) Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 + P LV+ +V+ ++G P ++W+KD + K I Sbjct: 5326 VKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDD---VELVSGPKCFIGLEG 5382 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 L + D T Y+ TN G S ++V E P Sbjct: 5383 STSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT-----EPP-------------- 5423 Query: 270 MIPYTHFDVQFLEKFGVT-FRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 +F++K + + G++ L+C + +P+++ V W+R++ L S Sbjct: 5424 ---------KFVKKLEASKIVKAGDSSRLECKIAGSPEIRVV-----WFRNEHELPASDK 5469 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA------DPLVTGA 382 +M F + A + ++L +D G + + G + S + V++ P+V Sbjct: 5470 YRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETL 5529 Query: 383 PGAPMDLQCHDANRDYVIVTW 403 A + L+C + V W Sbjct: 5530 KNAEVSLECELSGTPPFEVVW 5550 Score = 36.2 bits (82), Expect = 0.24 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V G + + V G P P V W K DQ ++ ++ + + + + I D Sbjct: 21074 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECVRSD 21132 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVY 1436 SG Y + +N G +T+ V+ Sbjct: 21133 SGPYPLTARNIVGEVGDVITIQVH 21156 Score = 36.2 bits (82), Expect = 0.24 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT G+ L+C + G P P++ W++ +++ S + + + + ++T+ ED Sbjct: 30542 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH-TLTVMTEEQEDE 30600 Query: 1414 GKYSINIKNKYG 1425 G Y+ N+ G Sbjct: 30601 GVYTCIATNEVG 30612 Score = 35.4 bits (80), Expect = 0.41 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP + + + E SV V G P P V W K G + YR + +Y Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-----YRYKVSYNKQ 1135 Query: 213 T----LEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 T L I+ DD Y+ V N HG+ S +A+++ Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1172 Score = 35.4 bits (80), Expect = 0.41 Identities = 46/222 (20%), Positives = 81/222 (36%), Gaps = 34/222 (15%) Query: 145 TFEERISRA--PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGK 202 T E ++ R P +++ S E + + V G P P W+ DG I K Sbjct: 1446 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVN-DYTHK 1504 Query: 203 YRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP 262 I+ + G +L I A D+ ++ VA N G+ S + + V +P Sbjct: 1505 VVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKP------- 1556 Query: 263 IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL 322 F+EK +EG + +K P+ P W ++ + Sbjct: 1557 ----------------MFVEKLKNVNIKEGSRLEMKVRATGNPN-----PDIVWLKNSDI 1595 Query: 323 LKESKWTKMFF--GEGQASLSFSHLHKDDEGLYTLRIVSRGG 362 + K+ K+ +G+A+L D YT +++ G Sbjct: 1596 IVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637 Score = 35.0 bits (79), Expect = 0.53 Identities = 55/234 (23%), Positives = 82/234 (35%), Gaps = 50/234 (21%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V+W+KDG+ I + KY I S V L IN+ DD A YS A Sbjct: 12404 VKWFKDGAEIKKGK---KYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR--------- 12451 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 S M+ + F + E +T+ L C + Sbjct: 12452 ----------------------TSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV--- 12486 Query: 305 PDLKRVQPRAE--WYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR-- 360 +P AE WY+ D + E+ ++ + L + H +D G Y R+ S Sbjct: 12487 -----SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRT 12541 Query: 361 -GGVSDHS-AFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 G V H A F+ L G + C +++ V WK + T ES Sbjct: 12542 DGKVKVHELAAEFISKPQNLEI-LEGEKAEFVC-SISKESFPVQWKRDDKTLES 12593 Score = 34.7 bits (78), Expect = 0.69 Identities = 51/233 (21%), Positives = 86/233 (36%), Gaps = 36/233 (15%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKY-RIESNYGVH 212 P I+ L+ E + V G V + KD + +P ++ R+ + Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI-----KPSRFFRMTQFEDTY 3399 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 LEI A +D TY+ VA+NA GQVS+ A L + P S + Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTA-----------------NLSLEAPESILHE 3442 Query: 273 YTHFDVQFLEKFGVTFRRE--------GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLK 324 +++ K +R+ G C + P++ R +W++ + Sbjct: 3443 RIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNV-----RFQWFKAGREIY 3497 Query: 325 ESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADP 377 ES + + +SL D G YT + + G +A L V +A P Sbjct: 3498 ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYP 3550 Score = 34.7 bits (78), Expect = 0.69 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 3/94 (3%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P +L+ SV + V G P V W+ +G+ I KY+ Sbjct: 7682 PSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGR---KYQTTLTDNTCA 7738 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247 L +N + D+ Y+ +ATN G +A + VR Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 7772 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 R + L + VT+++G+ L L+C + N + +V+W K+ + + V ++T Sbjct: 11213 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 11270 Query: 1405 IKGVTSEDSGKYSINIKN 1422 I D+G Y++ ++N Sbjct: 11271 INDADDTDAGTYTVTVEN 11288 Score = 33.5 bits (75), Expect = 1.5 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 2/94 (2%) Query: 161 RSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 +S V E+ + V G P P V+W K Q + G+ I LEI Sbjct: 8461 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR--QLNQGGRVFIHQKGDEAKLEIRDTT 8518 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEE 254 D+ Y VA N HG++ +N + V + E+ Sbjct: 8519 KTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEK 8552 Score = 33.1 bits (74), Expect = 2.0 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 900 DTSEPVLVEARP--GTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFK 957 +TS + +EA P TK I V + F+C+ D + TW K E+++ +++ Sbjct: 8822 ETSAELRIEAEPIQFTKRIQNIVVSEHQSAT-FECEVSFDDAIVTWYKGPTELTESQKYN 8880 Query: 958 IETVGDHSKLYLKNPDKEDLGTYSV 982 G + + N +D G YSV Sbjct: 8881 FRNDGRCHYMTIHNVTPDDEGVYSV 8905 Score = 33.1 bits (74), Expect = 2.0 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 3/93 (3%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + TV +K+ G PTP V W+KD + Q E+N Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN---SL 22204 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVV 246 L I A +D Y TN+ G+ V+V Sbjct: 22205 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237 Score = 32.0 bits (71), Expect = 4.5 Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 21/123 (17%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + E ++ C V + D V W+K ++ S+ ++ + + MTI VT +D Sbjct: 8843 IVVSEHQSATFECEVSFD-DAIVTWYKGPTELTESQKYNFR-NDGRCHYMTIHNVTPDDE 8900 Query: 1414 GKYSINIKNKYGGE-----KIDVTVSVYKHGEKIPDM--------------APPQQAKPK 1454 G YS+ + + GE ++ +T K K PD+ PP++ P Sbjct: 8901 GVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPV 8960 Query: 1455 LIP 1457 + P Sbjct: 8961 VAP 8963 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 28/108 (25%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQ--------------------DIQLSEHFSVKV 1395 + G + L ++ G+P P + W K++ ++Q E F + + Sbjct: 14691 VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPL 14750 Query: 1396 EQAKYVSMTIKGVTS--------EDSGKYSINIKNKYGGEKIDVTVSV 1435 Q + + KG + D G Y I ++N +G K TVSV Sbjct: 14751 TQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK-------NDQDIQLSEHFSVKVEQAKYVS 1402 L + + + EG +N+ + G P P + WFK N + + H + K+ + Sbjct: 16122 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 16180 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 + I D+G Y+I N G ++ ++V G P + P Sbjct: 16181 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL--GRPGPPVGP 16223 Score = 32.0 bits (71), Expect = 4.5 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G ++ + + G P PEV W K+ +I L +++ ++ + + I D+ Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTES-FTLLIIPECNRYDT 20842 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 GK+ + I+N G + V V V + ++ P K Sbjct: 20843 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK 20881 Score = 32.0 bits (71), Expect = 4.5 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 1364 LTCTVFGNP--DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIK 1421 LTC V + EV W+K+ + ++ + HF + I +T D G+Y I Sbjct: 32735 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 32794 Query: 1422 NKYGGEKIDV 1431 + G K ++ Sbjct: 32795 GEGGTSKTNL 32804 Score = 31.6 bits (70), Expect = 5.9 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 + G P V WY DG+ I + G I+ G+ T +I+ A +++ TY A N G Sbjct: 4885 ITGTPKIRVSWYLDGNEITAIQKHGISFID---GLATFQISGARVENSGTYVCEARNDAG 4941 Query: 237 QVSTNAAVVVR 247 S + + V+ Sbjct: 4942 TASCSIELKVK 4952 Score = 31.6 bits (70), Expect = 5.9 Identities = 15/59 (25%), Positives = 28/59 (47%) Query: 940 QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDP 998 + +W K E++ ++F+I GD L +KN +D G Y + + V++P Sbjct: 8687 KLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEP 8745 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 269 bits (688), Expect = 1e-71 Identities = 229/865 (26%), Positives = 373/865 (43%), Gaps = 101/865 (11%) Query: 153 APEILVRLR---SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 APEI + ++ TV ++L TV G P P + W K ++ Q + IE+ Sbjct: 7382 APEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK---RITIENVP 7438 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 T+ I + DT TY A N G+ + V V L Sbjct: 7439 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV--------------------LDK 7478 Query: 270 MIPYTHFDVQFL--EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK 327 P FD+ + E +T+ + K T V +R W++ +K++ Sbjct: 7479 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE--RRATDSEVWHKLSSTVKDTN 7536 Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAP 383 + + L + E ++ + + GV + A P+ P Sbjct: 7537 FKA------------TKLIPNKEYIFRVAAENMYGVGEPV------QASPITAKYQFDPP 7578 Query: 384 GAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYP 443 G P L+ D +D V +TW P+ SP+ GY+V+R + T+ WV+CN PVK Y Sbjct: 7579 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYR 7638 Query: 444 VTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD 503 V GL + Y FRV A N AG +PS+ ++ + DP+D Sbjct: 7639 VKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID--------------------- 7677 Query: 504 LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVGSGSWQRVNAQ 562 P PP ++ + V L+W P G + Y IE G+ W RV Sbjct: 7678 ------PPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV--A 7729 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 V + ++ + LMEG+ Y FRV + N+ G SEPSE + P+ ++ PS P + Sbjct: 7730 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7789 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 TK + ++W P+ + + Y V+ W+ + + + V LT G Y Sbjct: 7790 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVD-TTVKDTKCTVTPLTEGSLY 7848 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 +FRV A NA+G S+ ++ D + + T P PY + +++ + L W+ PK GG Sbjct: 7849 VFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGR 7908 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PI Y ++K+E W + + V + EG+ +F++ A N AG+G PS+P+ Sbjct: 7909 PIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT 7968 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 E E T P P P DL + + + WK P +G SP+ GY V+ +W+ Sbjct: 7969 EILSIEDPTSP-PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWM 8027 Query: 861 TVNQTTTANRYLKVSD-LQQGKTYVFRVRAVNANGVGKPSDTSEPVLV---EARP----G 912 VN + KV + + K YV RVRAVNA GV +PS+ SE V+ + +P Sbjct: 8028 RVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE 8087 Query: 913 TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 T +I E+ +I + F + S W K +E+ +R ++ DH +L+ P Sbjct: 8088 THDIIVIEGEKLSIPVPFRAVPVPTVS---WHKDGKEVKASDRLTMK--NDHISAHLEVP 8142 Query: 973 D--KEDLGTYSVSVSDTDGVSSSFV 995 + D G Y++++ + G +++ + Sbjct: 8143 KSVRADAGIYTITLENKLGSATASI 8167 Score = 268 bits (685), Expect = 3e-71 Identities = 209/769 (27%), Positives = 337/769 (43%), Gaps = 83/769 (10%) Query: 272 PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM 331 P DV+ L V + G + L T+ P+ P+ W + D++LK+ K + Sbjct: 7383 PEIFLDVKLLAGLTV---KAGTKIELPATVTGKPE-----PKITWTKADMILKQDKRITI 7434 Query: 332 FFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 +++++ + D G Y + V+ G + + V D PG P Sbjct: 7435 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK-------PGPPAAFDI 7487 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 D + ++TW PP S + Y V+R + W + + + VK + T L + Sbjct: 7488 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNK 7546 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 YIFRV A N G+ P + S A YQ D P Sbjct: 7547 EYIFRVAAENMYGVGEPVQASPITAK----------------------YQFD------PP 7578 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 GPPT + S+I+++ V L+W P G P+ Y++E+ + W R N + V+ Y Sbjct: 7579 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN-KMPVKDTTY 7637 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L K Y FRVL+ N G +PS+ T PI +D P PG+ KTSV + Sbjct: 7638 RVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRL 7697 Query: 631 QWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 W +P+H+ + Y ++ GT+ W + + + ++ GL G++Y FRV+AVN Sbjct: 7698 NWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVN 7756 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G SE S+ SD + + L PS P + ++N ++ L W VP+ GGSPI Y ++ Sbjct: 7757 KAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE 7816 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+V K W V+++ K T TV LTEGSLY F++AA N G + ++ + + Sbjct: 7817 KRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD- 7874 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 T PGP Y L +V + + W+ P G P+ Y ++ +E W+ +T Sbjct: 7875 TFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGP 7934 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNI 926 + +V+D+ +G F+VRA N GVG PS+ +E + +E P + + V + G Sbjct: 7935 DCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRK 7994 Query: 927 YLGFDCQ---------------EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 ++ + EM W + D +FK+E Sbjct: 7995 HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG--------VV 8046 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 PDKE Y + V + + V +P E+ + + PTI L++ Sbjct: 8047 PDKE----YVLRVRAVNAIG---VSEPSEISENVVAKDPDCKPTIDLET 8088 Score = 231 bits (588), Expect = 5e-60 Identities = 228/871 (26%), Positives = 358/871 (41%), Gaps = 147/871 (16%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 TV +V L TV G P P V W KDG+L+ + AE K ++ N + TLE+ + D Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLL-KPAEGIKMAMQRN--LCTLELFSVNRKD 13057 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y+ A N+ G S + V ++P G P + ++ M + ++ Sbjct: 13058 SGDYTITAENSSGSKSATIKLKVL-----DKP----GPPASVKINKM---------YSDR 13099 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 +++ E + T + + +P W ++ S S Sbjct: 13100 AMLSWEPPLEDGGSEITNYIVDKRETSRPN--------------WAQVSATVPITSCSVE 13145 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA------DPLVTGAPGAPMDLQCHDANRD 397 L + E + + ++ GV D +F A DP PG + +D Sbjct: 13146 KLIEGHEYQFRICAENKYGVGDP---VFTEPAIAKNPYDP-----PGRCDPPVISNITKD 13197 Query: 398 YVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRV 457 ++ V+WKPP SP+ GY +++ E NW + N P+ TGL EG Y FRV Sbjct: 13198 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13257 Query: 458 RAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGV 517 A+N AG +PS S A A DP PGPP Sbjct: 13258 TAINKAGPGKPSDASKAAYARDP---------------------------QYPPGPPAFP 13290 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM 576 + +R+ V LSW P G P++ Y +E S +W R N ++ R+ V LM Sbjct: 13291 KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLM 13350 Query: 577 EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV------- 629 E Y FRV + N+ G S+PS++ +D+ + P L + KT ++ Sbjct: 13351 EDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGE---LDADLRKTLILRAGVTMR 13407 Query: 630 ------------VQWDRPK-HEEDLLGYYVDCCVAGTNL-WEPCNHKPIGYNRFVVHGLT 675 + W +P + D +G + T L E N G Sbjct: 13408 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG---------- 13457 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +YI ++ N+ G E + V+KV L P P +T+ S + W+ P Sbjct: 13458 ---KYILTLE--NSCGKKEYTI---VVKV---LDTPGPPVNVTVKEISKDSAYVTWEPPI 13506 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGSPI+ Y + KR+ K+W V + SK T V L EG Y F++ A N GIG+ Sbjct: 13507 IDGGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGD 13565 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + K PGP DL V +S + WK P G S + GY VDF E+ Sbjct: 13566 PGETRDAVKAS----QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEE 13621 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKE 915 +W V ++ + K DL +GK Y FRV A N NG G PS+ + V AR Sbjct: 13622 -NKWQRVMKSLSLQYSAK--DLTEGKEYTFRVSAENENGEGTPSE----ITVVARDDV-- 13672 Query: 916 ISAGVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDH 964 ++ +D +G L + +E ++ A +W K + ++ D R +E+ + Sbjct: 13673 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13732 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + L + + K D G Y++++ + G + Sbjct: 13733 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13763 Score = 226 bits (575), Expect = 2e-58 Identities = 233/937 (24%), Positives = 390/937 (41%), Gaps = 106/937 (11%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E++S+ + F + P P V W+KDG + + +++++ LE+ ++ D Sbjct: 8097 EKLSIPVPF--RAVPVPTVSWHKDGK---EVKASDRLTMKNDHISAHLEVPKSVRADAGI 8151 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGV 286 Y+ N G + + V V IGLP P + K Sbjct: 8152 YTITLENKLGSATASINVKV----------------IGLPG----PCKDIKASDITKSSC 8191 Query: 287 TFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLH 346 E TP L V R E R + + GE + S + L Sbjct: 8192 KLTWEPPEFDGG-----TPILHYVLERREAGR-------RTYIPVMSGENKLSWTVKDLI 8239 Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANRDYVIVT 402 + E + ++ V++ G + ++ +P++ P P+D++ H+ + + +T Sbjct: 8240 PNGEYFFRVKAVNKVGGGE-----YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8294 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 WKPP S +MGY +++ G W +CN+ V I Y GL EG+ Y FRVRA N+ Sbjct: 8295 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8354 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPP----TGVH 518 AGIS PSR + A+DP+D + V L E+ D++ DA + G P T + Sbjct: 8355 AGISEPSRATPPTKAVDPIDAPK---VILRTSLEVK-RGDEIALDASISGSPYPTITWIK 8410 Query: 519 ASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSP-RYAVFDLME 577 + + P R + + E V+ QR++ + + + V D + Sbjct: 8411 DENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT--QRLSIDNSKKGESQLRVRDSLR 8468 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 ++ + N HG+++ S + P P + KTSV+ +W+ P Sbjct: 8469 PDHGLYMIKVENDHGIAKAPCTVSVLDT------PGPPINFVFEDIRKTSVLCKWEPPLD 8522 Query: 638 E--EDLLGYYVDCCVAGTNLWEPCNH-----KPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + +++ Y ++ + +P + + + ++ V L G++Y+FRV+A N Sbjct: 8523 DGGSEIINYTLE----KKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8578 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKR 750 G ++ + P P + + +SM + W PK GSPILGY+L+KR Sbjct: 8579 GPGPPCVSKPLV-AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKR 8636 Query: 751 EVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTM 810 EV+ +W VN S VDGL EG Y F++ A N AG G+ S PS+ K + Sbjct: 8637 EVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP-KTAHDPI 8695 Query: 811 PEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR 870 PGP + T++ + W+ P ++G + GYFVD + EW + R Sbjct: 8696 SPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVR 8754 Query: 871 YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 V ++++G Y RV AVNA G G P +T +PV V + V +G I + Sbjct: 8755 QYTVKEIREGADYKLRVSAVNAAGEGPPGET-QPVTVAEPQEPPAVELDVSVKGGIQIMA 8813 Query: 931 DCQEMTDA-------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 A W K E+ D +R I+ VG S+L +K+ ++D G Y ++ Sbjct: 8814 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8872 Query: 984 VSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 +++ G S F E+ ++ P + LK + K + W E Sbjct: 8873 ATNSCG--SKFAAARVEV-------FDVPGPVLDLKPVVTNR---KMCLLNWSDPEDDGG 8920 Query: 1044 DASYRFIINDREV------SDSEIHRIKCDKATGIIE 1074 FII ++ E R KCD TG++E Sbjct: 8921 SEITGFIIERKDAKMHTWRQPIETERSKCD-ITGLLE 8956 Score = 218 bits (554), Expect = 4e-56 Identities = 194/813 (23%), Positives = 330/813 (40%), Gaps = 104/813 (12%) Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPM 387 WT + SL + L + +E ++ + V++ GV + V +P V PG P Sbjct: 17461 WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVL--PGPPK 17518 Query: 388 DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGL 447 L+ + +D + V W P++ S ++GY V++ + W++CN + + VTGL Sbjct: 17519 SLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGL 17578 Query: 448 FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD 507 E Y FRV A N+AG+ PS + A DP+ Sbjct: 17579 TEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFK------------------------ 17614 Query: 508 AQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566 PGPPT H + ++N + L+W P G + L Y +E WQ V QT +R Sbjct: 17615 ---PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLR 17671 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD----------------VTV 610 R+ + L E + Y RV + N+ GL E + + ++ +D + V Sbjct: 17672 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 17731 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 R+ + + + W R + G + D K + Y + Sbjct: 17732 RAGGSARIHIPFKGRPTPEITWSREE------GEFTDKVQI---------EKGVNYTQLS 17776 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 + + + +K N+ G +S + V+ L P P + + S L Sbjct: 17777 IDNCDRNDAGKYILKLENSSG-----SKSAFVTVKV-LDTPGPPQNLAVKEVRKDSAFLV 17830 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W+ P GG+ + Y +DKRE K + V+S SK T V+ LTEG++Y F++ A N Sbjct: 17831 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAENE 17889 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 G+G P + + K P P +T +V TS ++W+ P + G S V GY V+ Sbjct: 17890 FGVGVPVETVDAVKAAE----PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17945 Query: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE-- 908 + + +W V ++ N V+ L G+ Y FRV+A N G P PV+ + Sbjct: 17946 MQPKGTEKWSIVAESKVCNAV--VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 18003 Query: 909 -ARPGTK------EISAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 +P K I AG D + I +G +W K E + R +E Sbjct: 18004 TIQPSLKLPFNTYSIQAGEDLKIEIPVIG------RPRPNISWVKDGEPLKQTTRVNVEE 18057 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTI-PLK 1019 + L++K +K+D G Y+V+ +++ G ++ E L + E P + P++ Sbjct: 18058 TATSTVLHIKEGNKDDFGKYTVTATNSAGTAT---------ENLSVIVLEKPGPPVGPVR 18108 Query: 1020 SELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDR 1079 + E+ V W + +I+ R+ + + H + A I++ + Sbjct: 18109 FD---EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 18165 Query: 1080 FSIENEGTYTVQIHDGK-AKSQSSLVLIGDAFK 1111 E + + GK A S V++ FK Sbjct: 18166 TGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 18198 Score = 216 bits (551), Expect = 1e-55 Identities = 213/874 (24%), Positives = 350/874 (40%), Gaps = 152/874 (17%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 T+ S++L +V G P PV+ W K G + A I++ L +++ + D Sbjct: 23152 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-----IDTTESYSLLIVDKVNRYD 23206 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGD-------EEPFRSVGLPIGLP-LSSMIPYTH 275 Y+ A N G+ S V V G E SV + +P + P + Sbjct: 23207 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23266 Query: 276 FDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE 335 + V+ E F+ TVT KC+ + V+ ++R +L E+ +G Sbjct: 23267 YIVEKREAAMRAFK----TVTTKCSKTLYRISGLVEGTMYYFR---VLPEN-----IYGI 23314 Query: 336 GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDAN 395 G+ + + LV+ P P L+ D Sbjct: 23315 GEPCETSDAV--------------------------------LVSEVPLVPAKLEVVDVT 23342 Query: 396 RDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIF 455 + V + W+ P S + GY ++ C+ GT W++ + ++ VT L EG Y+F Sbjct: 23343 KSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLF 23402 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP-GPP 514 R+RA N G+S P + V A+ DLR L + L + I+ VP G P Sbjct: 23403 RIRAQNEKGVSEPR---ETVTAVTVQDLRVLPTIDLSTMPQKTIH---------VPAGRP 23450 Query: 515 TGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 + R SW +F + S +RV +T + + + + Sbjct: 23451 VELVIPIAGRPPPAASW------------FFAGSKLRES---ERVTVETHTKVAKLTIRE 23495 Query: 575 LMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 + + + N G L +P T PI+ ++ Sbjct: 23496 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA-------------- 23541 Query: 625 KTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIF 682 TS+ + W+ P+ + L GY V+ A W P + + + F LT G +Y+F Sbjct: 23542 -TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVF 23599 Query: 683 RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 RV A N G+ Q S+VI+ ++++ +P P + + + MTL W P+ GGS + Sbjct: 23600 RVAATNRFGIGSYLQ-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23658 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 GY ++++EV W VN P T GLTEG YE ++ A+N G G+PS PS+ Sbjct: 23659 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23718 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P PG + + TS+ + W P G S V+GY ++ ++ D EW Sbjct: 23719 IVAMDPIAP-PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKC 23777 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 N T T R ++ L QG Y FRV A NA G G+P++ PGT +++ ++ Sbjct: 23778 NTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLE- 23827 Query: 923 QGNIYLGFDCQEMTDASQFT---------------------WCKSYEEISDDERFKIETV 961 Y ++ E F W K ++IS +R I T Sbjct: 23828 ----YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATS 23881 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 H++L +K D+ D GTY + + + G + ++ Sbjct: 23882 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23915 Score = 216 bits (549), Expect = 2e-55 Identities = 172/613 (28%), Positives = 259/613 (42%), Gaps = 54/613 (8%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 ++ P +P A W D +L+ KM A L S + D+G+YTL++ +R Sbjct: 7109 ILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR- 7167 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 V S + D V P AP +L+ D +D V +TW+PP+ SP+ GY V++ Sbjct: 7168 -VKTISG-----EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEK 7221 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 EV W + D V ++ V L +G+ Y+F+V A N G P+ V + V P Sbjct: 7222 REVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTP- 7279 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 A VP PP V + + N + L+W+PP G Sbjct: 7280 --------------------------ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSR 7313 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ GS W V V + V L EGK Y +RV + NR G S+PS T Sbjct: 7314 IKGYIVERCPRGSDKW--VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7371 Query: 601 SPIQAQDVTVVPS--APGRVLASRNTKTSVVVQWDRP---KHEEDLLGYYVDCCVAGTNL 655 IQA D P ++LA K ++ K E + D + Sbjct: 7372 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7431 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY 715 N V + YI ++AVN G + E +V L P P Sbjct: 7432 ITIENVPKKSTVTIVDSKRSDTGTYI--IEAVNVCGRATAVVEVNV------LDKPGPPA 7483 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL 775 + + S L W P+ GGS I Y +++R + WH++ SS K T L Sbjct: 7484 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL-SSTVKDTNFKATKL 7542 Query: 776 TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKA 835 Y F++AA N+ G+GEP S + PGP L ++ ++ + W Sbjct: 7543 IPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTLTWCE 7600 Query: 836 PVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 P G SP++GY+V+ + D +W+ N+ + +V L K Y FRV A N G Sbjct: 7601 PDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGP 7660 Query: 896 GKPSDTSEPVLVE 908 GKPS ++EP+L++ Sbjct: 7661 GKPSKSTEPILIK 7673 Score = 207 bits (526), Expect = 8e-53 Identities = 199/842 (23%), Positives = 329/842 (39%), Gaps = 127/842 (15%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 ++G P P V W KDG + + A + I+S TL + D Y +N G Sbjct: 18426 IRGKPIPDVVWSKDGKELEETA--ARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18483 Query: 237 QVSTNAAVVVRRFRGDEE-PFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETV 295 S V V G E P + G+ Sbjct: 18484 TKSIPITVKVLDRPGPPEGPLKVTGV---------------------------------T 18510 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKES----KWTKMFFGEGQASLSFSHLHKDDEG 351 KC + P L+ Y ++ K WT++ + + L +E Sbjct: 18511 AEKCYLAWNPPLQDGGANISHY---IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEY 18567 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 ++ + V++ G+ + V +P PG P + +D ++VTW P Sbjct: 18568 IFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITKDSMVVTWARPVDDGG 18625 Query: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRV 471 + + GY +++ + W +CN + + VTGL EG SY FRV A N+AG+ PS Sbjct: 18626 TEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEP 18685 Query: 472 SDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW 531 S A D A+Y PGPP+ ++ SR+ V L+W Sbjct: 18686 SVFYRACD------------------ALYP---------PGPPSNPKVTDTSRSSVSLAW 18718 Query: 532 EPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANR 590 P G P+ Y +E + W T ++ ++ V L E Y FR+ + N Sbjct: 18719 SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINS 18778 Query: 591 HGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTKTSVVVQWDR 634 G+ EP+ + + AQ+ V + SA R+ + + V+W++ Sbjct: 18779 EGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK 18838 Query: 635 PKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 E +L V + + V+ +T + + + N Sbjct: 18839 A---EGILTDRAQIEVTSS------------FTMLVIDNVTRFDSGRYNLTLEN------ 18877 Query: 695 NSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 NS L PS P +T+ S+TL W+ P GG+ I Y ++KRE Sbjct: 18878 NSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 18937 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 K + + ++ +K T ++ L EG Y F++ A N GIG P++ +E K +P PG Sbjct: 18938 KAYATITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLP-PG 18995 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 +T +V + + W+ P G S ++GY V+ + + + +W T Q T + Sbjct: 18996 ---RVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE--ATI 19050 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL---VEARPGTK----EISAGVDEQGNIY 927 S L G+ YVFRV AVN G P PV+ +E +P + + EQ I Sbjct: 19051 SGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKID 19110 Query: 928 LGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 + F + + W K + + + R + + + L +K KED+GTY + VS++ Sbjct: 19111 VPFKGRPQATVN---WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 19167 Query: 988 DG 989 G Sbjct: 19168 AG 19169 Score = 206 bits (525), Expect = 1e-52 Identities = 201/762 (26%), Positives = 307/762 (40%), Gaps = 95/762 (12%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + ++++ +K+ V G P P + W KDG + Q + +E Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT---RVNVEETATSTV 18063 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I + DD Y+ ATN+ G + N +V+V E+P G P+G + + Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVL-----EKP----GPPVG-----PVRF 18109 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 F V E T C + KR W+ + Sbjct: 18110 DEVSADF-----VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATV---------- 18154 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCH 392 + ++ + L E + + +R G S V P G PG P Sbjct: 18155 --ARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VT 18209 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 ++D ++V W P + ++GY +++ E + WV+ N P++ K+ TGL EG Sbjct: 18210 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 18269 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y F+V A N GI +PS+VS+ A DP D Sbjct: 18270 YEFKVSAENIVGIGKPSKVSECFVARDPCD------------------------------ 18299 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYA 571 PP A I+RN V L W+ P G + Y +EK + G W + + T V + Sbjct: 18300 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TNVLETEFT 18358 Query: 572 VFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L+E + Y FRV++ N G SEPS+ + I A+D AP L + VV Sbjct: 18359 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEI---DAPNASLDPKYKDVIVVH 18415 Query: 631 QWDRPKHEEDLLGYYVDCCV---AGTNLWEPCNH----KPIGYNRFVVHGL--TTGEQYI 681 + E D+ G + V G L E I VV T G QYI Sbjct: 18416 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGS 740 ++ V +S I V+ L P P G + + L W P GG+ Sbjct: 18476 LKLSNVGGT-------KSIPITVK-VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18527 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I Y ++KRE +W +V S+ + V L G+ Y F++ AVN GIGEP + Sbjct: 18528 NISHYIIEKRETSRLSWTQV-STEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESG 18586 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 C + PGP + S+V+ W PV G + + GY ++ R+++ W Sbjct: 18587 PVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18644 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 N+ T + L+V+ L +G +Y FRV A NA GVG+PS+ S Sbjct: 18645 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18686 Score = 206 bits (525), Expect = 1e-52 Identities = 205/865 (23%), Positives = 323/865 (37%), Gaps = 151/865 (17%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 S+++ VQG P P V W+KDG + + I G +L + A D Y+ Sbjct: 21670 SLRIKALVQGRPVPRVTWFKDG---VEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTV 21726 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEE-PFRSVGLP-------IGLPLSS-MIPYTHFDVQF 280 A NA G V V+ G P R + PL+ P TH+ ++ Sbjct: 21727 EAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEK 21786 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 E T R + KC +K + +R + K FG G+ Sbjct: 21787 RE----TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNK--------FGVGRPL- 21833 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANR 396 D+DP+V P AP + + Sbjct: 21834 ---------------------------------DSDPVVAQIQYTVPDAPGIPEPSNITG 21860 Query: 397 DYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQC-NDAPVKICKYPVTGLFEGRSYIF 455 + + +TW P + S + Y ++R E + WV+ + P+ ++ VTGL EG Y F Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 21920 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPT 515 V A N+AG+ S +S + +P++ PGPPT Sbjct: 21921 HVMAENAAGVGPASGISRLIKCREPVN---------------------------PPGPPT 21953 Query: 516 GVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 V ++ S+ V L W P G + + Y IE G W +VNA+ V++ RY V D Sbjct: 21954 VVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT-RYTVTD 22012 Query: 575 LMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS----------------APGRV 618 L G+ Y FRV + N G + E+T I+A D P A R+ Sbjct: 22013 LQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRL 22072 Query: 619 LASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 + + + W +P L T E CN G V + + Sbjct: 22073 FIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSK 22132 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 F VK L P P IT + S TL W P G Sbjct: 22133 SITFTVKV---------------------LDTPGPPGPITFKDVTRGSATLMWDAPLLDG 22171 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+ I Y ++KRE ++W ++ ++ I V+ L EG Y F+++AVN G+GEP + Sbjct: 22172 GARIHHYVVEKREASRRSWQVISEKCTRQ-IFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22230 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E +P P L + +S V+ W P + G S ++GY ++ R++ + Sbjct: 22231 MPEPIVATE----QPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22286 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W+ T V L + Y FRV+A N G +P + V+++ +I Sbjct: 22287 WVEAGHTKQLT--FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE----PQIEP 22340 Query: 919 GVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDHSKL 967 D G C+ + A + TW + + +R I T D + L Sbjct: 22341 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTL 22400 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSS 992 +K+ + D G Y +++ +T GV + Sbjct: 22401 TVKDSMRGDSGRYFLTLENTAGVKT 22425 Score = 206 bits (523), Expect = 2e-52 Identities = 163/604 (26%), Positives = 252/604 (41%), Gaps = 58/604 (9%) Query: 311 QPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 +P+ W++D+ + E T + +L + D G Y +V F Sbjct: 10542 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC--VVVENSTGSRKGFC 10599 Query: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 V D G P P+ + +DY++++WKPP S + Y +++ EVG + W+ Sbjct: 10600 QVNVVDR--PGPPVGPVSFD--EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 10655 Query: 431 QCNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAV 489 A K CK V+ L EG+ YIFR+ A N GIS P VSD++ A D Sbjct: 10656 PVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL-VSDSMKAKDRF-------- 10704 Query: 490 HLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKS 549 +VP P +E++++ +++W P GK Y +EK Sbjct: 10705 -------------------RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR 10745 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W RV ++ V DL+EG Y FRV + N G+ +PS + P+ A+D Sbjct: 10746 ETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI 10805 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 PS P A T SV + W P+H+ +LGY V+ G W NH P Sbjct: 10806 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 10865 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 ++ V GL G+ Y FRV AVNA G S+ + + + V+ L P + Sbjct: 10866 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10925 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 + ++ G P K + PT +D GS E + Sbjct: 10926 KVGDTLRLSAIIKGVPFPKVTWKKED------------RDAPTKARIDVTPVGSKLEIRN 10973 Query: 786 AAVNLAGI----GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 AA GI E S+ + + +PGP DL E+R S + WK P+ G Sbjct: 10974 AAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGG 11033 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y V+ R+ + +W ++ T+ + L +G Y+FRV A N G G +T Sbjct: 11034 SVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGPFVET 11092 Query: 902 SEPV 905 +P+ Sbjct: 11093 PKPI 11096 Score = 204 bits (520), Expect = 4e-52 Identities = 208/851 (24%), Positives = 344/851 (40%), Gaps = 108/851 (12%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLE------INRADFDDT 224 +++ ++G PTP W DG +A + G + I + + T E I T Sbjct: 9523 IRIPAVIKGRPTPKSSWEFDGKAK-KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9581 Query: 225 ATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF 284 YS A N GQ + N V V G + + + G Sbjct: 9582 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRG-------------------- 9621 Query: 285 GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSH 344 + L M PD + + + WTK+ G + Sbjct: 9622 ---------SCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPD 9669 Query: 345 LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTW 403 L + + + +R +R G+ + A DP+ P P+ L+ ++ V ++W Sbjct: 9670 LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYP--PDPPIKLKIGLITKNTVHLSW 9727 Query: 404 KPPNTTTESPVMGYFVDRCE---VGTNN--WVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 KPP SPV Y V+ GT W QCN V+ ++ V L EG Y FRV+ Sbjct: 9728 KPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVK 9787 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD--AQVPGPPTG 516 AVN+AG+S+PS A + P D +R KE ++ + A++ G P Sbjct: 9788 AVNAAGVSKPS------ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVP-- 9839 Query: 517 VHASEISRNYVVLSW---EPPTPRGKDPLMY--FIEKSVVGSGSWQRVNAQTAVRSPRYA 571 + L+W P P K+P++Y + K VV + + Y Sbjct: 9840 ---------FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT 9890 Query: 572 VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 + + + + N L P PI+ + V+ + + Sbjct: 9891 I-TAVNNLGTASKEMRLNV--LGRPGPPVGPIKFESVSA---------------DQMTLS 9932 Query: 632 WDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 W PK + + Y ++ A W + +P + + L G +Y+FR+ A N Sbjct: 9933 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNK 9991 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 G+ E +S+ + +VP P T+ + +SMT+ W+ P++ GGSP+ GY+L+ Sbjct: 9992 YGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM 10050 Query: 750 REVHHKNWHEVNSSPSKPTIL----TVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++ K W VN P K L V GL EGS Y+F++ A+N AG+G S PS+ Sbjct: 10051 KDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 10110 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P PGP + + +S + W P+ G S V+GY V+++EE EW Sbjct: 10111 RDPIAP-PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 10168 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--PGTKEISAGVDEQ 923 L V+ L++G Y FRVRAVN G+G+P + ++ + ++ R ++ A V ++ Sbjct: 10169 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDR 10228 Query: 924 GNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLG 978 ++ G + + S TW + E + + IET S + +KN + G Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10286 Query: 979 TYSVSVSDTDG 989 YS+ + G Sbjct: 10287 VYSLLAKNEAG 10297 Score = 203 bits (516), Expect = 1e-51 Identities = 211/854 (24%), Positives = 339/854 (39%), Gaps = 152/854 (17%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFD-----------DTA 225 V G P P ++W KDG + G LEI ADF D+ Sbjct: 15180 VSGRPPPTMEWSKDGKEL--------------EGTAKLEIKIADFSTNLVNKDSTRRDSG 15225 Query: 226 TYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFG 285 Y+ ATN G V V G E PL+ Sbjct: 15226 AYTLTATNPGGFAKHIFNVKVLDRPGPPEG----------PLA----------------- 15258 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK---WTKMFFGEGQASLSF 342 VT E + KC + P L + + Y V +E+ WT + L Sbjct: 15259 VT-----EVTSEKCVLSWFPPLDDGGAKIDHYI--VQKRETSRLAWTNVASEVQVTKLKV 15311 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + L K +E ++ + V++ GV + V +P G P P + + +D ++V Sbjct: 15312 TKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY--GPPDPPKNPEVTTITKDSMVVC 15369 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P++ S ++ Y V+R + W++CN + +Y V+GL EG Y FR+ A N+ Sbjct: 15370 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15429 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AGIS PS S A D +++ PGPP + Sbjct: 15430 AGISAPSPTSPFYKACD------------------TVFK---------PGPPGNPRVLDT 15462 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 SR+ + ++W P G + Y +E ++ WQ V +++ Y + L E + Y Sbjct: 15463 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15522 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTK 625 R+ + N GL EP+ + +A+D VT+ R+ + Sbjct: 15523 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 15582 Query: 626 TSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685 + V+W R H E L ++ + T L NRF +YI V+ Sbjct: 15583 PAPEVKWARD-HGESLDKASIESTSSYTLLIVG------NVNRF------DSGKYILTVE 15629 Query: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 + + +S + V+ L P P + + S+TL W P GGS I Y Sbjct: 15630 -------NSSGSKSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNY 15681 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++KRE K + V ++ K T VD L EG Y F++ A N GIG P++ +E K Sbjct: 15682 IVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 15740 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 +P PG +T +V S+ + W+ P + G S + GY V+ + + + +W T Sbjct: 15741 SERPLP-PGK---ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--A 15794 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---------GTKEI 916 T ++ L QG+ Y FRV A N G+ P S PV+ + T + Sbjct: 15795 TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV 15854 Query: 917 SAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKE 975 AG D + ++ ++G TW K + R E+ ++S L +K+ +E Sbjct: 15855 LAGEDLKVDVPFIG------RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15908 Query: 976 DLGTYSVSVSDTDG 989 D+G Y V ++++ G Sbjct: 15909 DVGHYVVKLTNSAG 15922 Score = 200 bits (508), Expect = 1e-50 Identities = 212/862 (24%), Positives = 330/862 (38%), Gaps = 118/862 (13%) Query: 165 VWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH----TLEINRAD 220 V E +V + ++G P P + W+K EP Y N V TL I ++ Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9882 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQF 280 DT Y+ A N G S + V G P+G P+ F+ Sbjct: 9883 RSDTGLYTITAVNNLGTASKEMRLNV---------LGRPGPPVG-PIK-------FESVS 9925 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 ++ +++ + K T V KR R W KE +T EG Sbjct: 9926 ADQMTLSWFPPKDDGGSKITNYVIE--KREANRKTWVHVSSEPKECTYTIPKLLEGHE-- 9981 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 Y RI+++ + + PGAP R+ + Sbjct: 9982 ------------YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMT 10029 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC----KYPVTGLFEGRSYIFR 456 V W+ P SPV GY+++ + + W + N P+K Y VTGL EG Y FR Sbjct: 10030 VNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 10089 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 V A+N+AG+ S SD A DP+ PGPP Sbjct: 10090 VYAINAAGVGPASLPSDPATARDPI---------------------------APPGPPFP 10122 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDL 575 ++ +++ L W PP G + Y +E G W++ VR + V L Sbjct: 10123 -KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GKDKEVRGTKLVVTGL 10180 Query: 576 MEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--------------APG--RVL 619 EG Y FRV + N G+ EP E+T I+ +D V P A G R++ Sbjct: 10181 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10240 Query: 620 ASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 A + K V W+ + ++ + + + C Q Sbjct: 10241 AYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS---------------HQ 10285 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 ++ + A N G + + DV+ V + P + +T +C L W P+ GG Sbjct: 10286 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCK-----LTWFSPEDDGG 10340 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPI Y ++KRE + W V + ++ TV GL +G Y F+IAA N G+G + Sbjct: 10341 SPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSIGMGPFVET 10399 Query: 800 SEHFKC-EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 SE E T+PE DL EV ++ + W P Y G S + Y ++ R + Sbjct: 10400 SEALVIREPITVPERPE--DLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10457 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 + V +R V L++G TY +RV AVN G GKPS ++P+ + + Sbjct: 10458 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10517 Query: 919 GVDEQGNIYLGFDCQEMTDA------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 ++ I +G + +T + +W K ++ +D+R I+T L Sbjct: 10518 DFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 10576 Query: 973 DKEDLGTYSVSVSDTDGVSSSF 994 + D G Y V V ++ G F Sbjct: 10577 KRSDSGKYCVVVENSTGSRKGF 10598 Score = 199 bits (506), Expect = 2e-50 Identities = 202/839 (24%), Positives = 329/839 (39%), Gaps = 101/839 (12%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +V+ ++G P P +W DGS I Y +E++ L I DT Y Sbjct: 11222 TVRFPAIIRGVPVPTAKWTTDGSEI---KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 +NA G + + V G P G P DV Sbjct: 11279 TVSNAAGSKTVAVHLTVLDVPGP---------PTG-------PINILDVT---------- 11312 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 E T++ + P P + + ++ W + G + L HL K Sbjct: 11313 PEHMTISWQ-----PPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11367 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAPGAPMDLQCHDANRDYVIVTWKP 405 E ++ +R ++ GV D+ P V P P D + V+W Sbjct: 11368 EYVFRVRAENKIGVGPPL------DSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTL 11421 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + SP+ GY+++R EV T WV+ N P+ K+ VTGL+EG +Y FRV A N AG+ Sbjct: 11422 PKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGL 11480 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 S+PS SD + A P+ + PGPP + SR Sbjct: 11481 SKPSPSSDPIKACRPI---------------------------KPPGPPINPKLKDKSRE 11513 Query: 526 YVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 L W P G P++ Y +E G+ W R+N +R + V L+EG Y FR Sbjct: 11514 TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFR 11573 Query: 585 VLSANRHGLSEPSEITSPIQAQDVTVVPSAP-----GRVLASRNTKTSVVVQWDRPKHEE 639 + +AN G EP E+ + A+D+ P V+ R +T ++ + + E Sbjct: 11574 IKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEP 11633 Query: 640 DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQES 699 D+ + + P + +YI ++A S ++Q S Sbjct: 11634 DITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI-----ISAKNSSGHAQGS 11688 Query: 700 DVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHE 759 ++ V L P + + N + T+ W+ P +GGS I + ++ R+ + K W Sbjct: 11689 AIVNV---LDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSI 11745 Query: 760 VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDL 819 V S +K I L + Y F++ A N G+G P+ ++ + PG +L Sbjct: 11746 VASDVTKRLIKA--NLLANNEYYFRVCAENKVGVG-PTIETKTPILAINPIDRPGEPENL 11802 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + T + + W+ P Y G SP Y V+ R + + +W V++ + + V + Sbjct: 11803 HIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVE 11862 Query: 880 GKTYVFRVRAVNANG---------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 + Y FRV+ N G V D +PVL G + AG + + G Sbjct: 11863 NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG--DTIRLEAGV 11920 Query: 931 DCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + + + +T K +++ R KI+T D SK L + D G Y V+ ++T G Sbjct: 11921 RGKPFPEVA-WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978 Score = 198 bits (503), Expect = 4e-50 Identities = 178/670 (26%), Positives = 280/670 (41%), Gaps = 68/670 (10%) Query: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313 EP S G PI + P DV+F + V + GE + + + P P Sbjct: 19465 EPSESTG-PIIVKDDVEPPRVMMDVKFRDVIVV---KAGEVLKINADIAGRP-----LPV 19515 Query: 314 AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W +D + ++E T++ + L+ + D G Y L + + G + V Sbjct: 19516 ISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 19575 Query: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433 D G P P+++ A + ++W P + + Y V++ E W C Sbjct: 19576 DK----PGPPAGPLEINGLTAEK--CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC- 19628 Query: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493 + +++ VT L +G YIFRV VN G+ P S A+ ALDP Sbjct: 19629 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKALDPF------------ 19675 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVG 552 VP PPT + + +++ + L W P G + Y IE+ Sbjct: 19676 ---------------TVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19720 Query: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612 S W RVN + V R L EG Y +RV + N GLS PSE + I+A+D +P Sbjct: 19721 SLRWVRVN-KKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19779 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 S P + + KT++ + W +P + + GY V+ + W+ G + Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19838 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVP----SHPYGITLLNCDGHS 726 + GLTTG +Y+FRVK+VN VG S+ S SD + P TL+ G S Sbjct: 19839 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19898 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 T+ VP G P+ K + + V+++ S+ T LT++ ++ + Sbjct: 19899 FTM--TVP--FRGRPVPNVLWSKPDTDLRTRAYVDTTDSR-TSLTIENANRNDSGKYTLT 19953 Query: 787 AVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSG 846 N+ + + PGP ++T +V S V+ W P G +PV Sbjct: 19954 IQNVLS-------AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKN 20006 Query: 847 YFVDFREEDAGEWITVNQTTTANRY-LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE W++V T NR KV++LQ+G Y FRV N GVG P++T E V Sbjct: 20007 YHIEKREASKKAWVSV--TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 20064 Query: 906 LVEARPGTKE 915 + +P E Sbjct: 20065 KITEKPSPPE 20074 Score = 196 bits (497), Expect = 2e-49 Identities = 206/843 (24%), Positives = 341/843 (40%), Gaps = 125/843 (14%) Query: 170 SVKLCFTVQGFPTPVVQWYKD------GSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 SVKL + G P P ++WYKD +L+C +E+ + ++ I AD + Sbjct: 20584 SVKLRAGISGKPAPTIEWYKDDKELQTNALVC---------VENTTDLASILIKDADRLN 20634 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y NA G S V + G P G P+ F EK Sbjct: 20635 SGCYELKLRNAMGSASATIRVQILDKPG----------PPGGPIE-------FKTVTAEK 20677 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 + +R + K T + KR R W L+E ++ + Sbjct: 20678 ITLLWRPPADDGGAKITHYIVE--KRETSRVVWSMVSEHLEE------------CIITTT 20723 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-GAPGAPMDLQCHDANRDYVIVT 402 + K +E ++ +R V++ G+ + V + VT G PG P + ++ + V Sbjct: 20724 KIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKITKNSMTVV 20780 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P S + GYF+++ + + W + ++ + VTGL E Y +RV AVN+ Sbjct: 20781 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 20840 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AG S S+ A DP+D PGPP + ++ Sbjct: 20841 AGQGPFSEPSEFYKAADPID---------------------------PPGPPAKIRIADS 20873 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 +++ + L W P G + Y +E W V+ + VR+ Y V +L G +Y Sbjct: 20874 TKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNY 20933 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP------GRVLASRNTKTSVVVQWD-R 634 FRV + N G EP E+ P+QA+D+ P V+A V++ + R Sbjct: 20934 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGR 20993 Query: 635 P------KHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 P + +E LG + T+ + N TG+ YI ++ N Sbjct: 20994 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN-------DTGK-YILTIE--N 21043 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 VG ++S S +KV L P+ + + + ++TL W P GGSPI+ Y ++ Sbjct: 21044 GVGEPKSSTVS--VKV---LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE 21098 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+ + W V+ S + +D L+E + + F++ A N GIGEP + +E K Sbjct: 21099 KRDATKRTWSVVSHKCSSTSFKLID-LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE- 21156 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 P P DL+ + TS+++ W P + G S ++ Y V+ + + W + T Sbjct: 21157 ---VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 21213 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG---- 924 ++VS L++ FRV A N G+ P T P+ V+ T E+ D G Sbjct: 21214 E--IEVSQLKEQSVLEFRVFAKNEKGLSDPV-TIGPITVKELIITPEVDLS-DIPGAQVT 21269 Query: 925 -----NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGT 979 N++L + S +W K + + E + + L +KN KE G Sbjct: 21270 VRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGK 21328 Query: 980 YSV 982 Y+V Sbjct: 21329 YTV 21331 Score = 194 bits (493), Expect = 5e-49 Identities = 199/802 (24%), Positives = 323/802 (40%), Gaps = 126/802 (15%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P R P +W + D ++++ + SL ++++ D G YTL + + Sbjct: 16657 LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSS 16714 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G SAF+ VR D P P++L+ + +D V +TW+PP S + Y V++ Sbjct: 16715 GTK--SAFVTVRVLD-----TPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16767 Query: 422 CEVGTNNWVQCNDAPVKIC---KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478 E ++ A V C + + L EG SY FRV A N GI P++ +D + Sbjct: 16768 REATRKSYA----AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV- 16822 Query: 479 DPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRG 538 A+VP PP + +++RN V LSW P G Sbjct: 16823 -----------------------------AEVPQPPGKITVDDVTRNSVSLSWTKPEHDG 16853 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 ++ Y +E S W V+S + + +L +G+ Y+FRV++ N G S+P Sbjct: 16854 GSKIIQYIVEMQAKHSEKWSEC---ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16910 Query: 598 EITSPIQAQDVTVVPS-----APGRVLASRNTKTSVVVQWDRPKHE----------EDLL 642 + PI A+D+ + P + V ++ K V + RPK + Sbjct: 16911 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPIS-GRPKPTITWTKDGLPLKQTT 16969 Query: 643 GYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVI 702 V + T L HK G QY + N VG S E Sbjct: 16970 RINVTDSLDLTTLSIKETHK------------DDGGQY--GITVANVVGQKTASIEI--- 17012 Query: 703 KVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 L P P G + + S+TL W P ++GG I Y + KR+ W V+ Sbjct: 17013 ---VTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 17069 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAG--IGEPSDPSEHFKCEAWTMPEPGPAYDL 819 ++ ++ T L V L G+ Y+F+I A N G SDP + EPGP Sbjct: 17070 ATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI----VAQYPYKEPGPPGTP 17124 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + S+V+ W PV +G SPV GY ++ +E ++ W VN+T + K +L++ Sbjct: 17125 FATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEE 17184 Query: 880 GKTYVFRVRAVNANGVGK---------------PSDTSEPVLVEARPGTKEISAGVDEQG 924 G Y FRV A N GVGK P T EP++V+ T + + V + G Sbjct: 17185 GIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGG 17244 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 ++ G+ E D W K+ + +F + + + + + K G S Sbjct: 17245 SMITGY-IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17303 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAE-HLSP 1043 T +++ +E++ P I + + I F L+A+ H P Sbjct: 17304 DSTGPITA---------------KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKP 17348 Query: 1044 DASYRFIINDREVSDSEIHRIK 1065 + ++ D+E+ +S IK Sbjct: 17349 LPTIEWLRGDKEIEESARCEIK 17370 Score = 193 bits (490), Expect = 1e-48 Identities = 206/864 (23%), Positives = 336/864 (38%), Gaps = 147/864 (17%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 +K+ + G P PV+ W KDG + E + I S L + DT Y Sbjct: 19502 LKINADIAGRPLPVISWAKDG---IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19558 Query: 231 ATNAHG--QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF 288 N G V+ N V+ ++P G P G LE G+T Sbjct: 19559 LKNVAGTRSVAVNCKVL-------DKP----GPPAGP---------------LEINGLTA 19592 Query: 289 RREGETVTLKCTMLVTPDLKRVQPRAEWYRD-DVLLKESK------WTKMFFGEGQ-ASL 340 KC+ L +P+ + D D + E + WT + GE Q S Sbjct: 19593 E--------KCS------LSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSC 19637 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 + L K +E ++ + V++ GV + + ++ DP +P P L+ ++ + Sbjct: 19638 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEITSVTKESMT 19695 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + W P + S + GY ++R E + WV+ N PV + TGL EG Y +RV A Sbjct: 19696 LCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAE 19755 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 N+AG+S PS S + A DP+ L P PP+ Sbjct: 19756 NAAGLSLPSETSPLIRAEDPVFL---------------------------PSPPSKPKIV 19788 Query: 521 EISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGK 579 + + + ++W P G P+ Y +E W+ + ++R Y + L G Sbjct: 19789 DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK--TSIQSLRGTEYTISGLTTGA 19846 Query: 580 SYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV---------- 629 YVFRV S N+ G S+PS+ + P A++ P + S KT +V Sbjct: 19847 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD---IDSEMRKTLIVKAGASFTMTV 19903 Query: 630 ---------VQWDRPKHEEDL-LGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGE 678 V W +P + DL YVD + T+L E N G + + + Sbjct: 19904 PFRGRPVPNVLWSKP--DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19961 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 VK L P P IT+ + S L W VP+ G Sbjct: 19962 SLTLVVK---------------------VLDTPGPPTNITVQDVTKESAVLSWDVPENDG 20000 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+P+ Y+++KRE K W V ++ ++ + V L EG++Y F+++ N G+G P++ Sbjct: 20001 GAPVKNYHIEKREASKKAWVSVTNNCNRLS-YKVTNLQEGAIYYFRVSGENEFGVGIPAE 20059 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E K +P P L + S+ + W P + G S + Y V+ E+ Sbjct: 20060 TKEGVK----ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKN 20115 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W V + + VS L++ Y FRV A N G+ P + PVL++ + EI Sbjct: 20116 W--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDM 20173 Query: 919 GVDEQGNIYLGFDCQEMTD-------ASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 +Y+ D + T + + RF E ++ + LK Sbjct: 20174 KNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKE 20233 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFV 995 D G Y ++ +++ G + +F+ Sbjct: 20234 SVTADAGRYEITAANSSGTTKAFI 20257 Score = 192 bits (489), Expect = 2e-48 Identities = 159/642 (24%), Positives = 274/642 (42%), Gaps = 79/642 (12%) Query: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438 +T P P L ++D V +TW P S ++ Y V+ E G NWV+C A K Sbjct: 20066 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAK 20123 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIA 498 + V+GL E Y FRV A N AG+S P + V + L+ + + Sbjct: 20124 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 20183 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVL--SWEPPTPRGKDPLMYFIEKSVVGSGSW 556 +L+ D + G P + +SR+ V L + T + L +++SV Sbjct: 20184 RAGSNLKVDIPISGKP--LPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGR 20241 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG 616 + A + + K+++ V+ L P T P+ D+T Sbjct: 20242 YEITAANSSGTT----------KAFINIVV------LDRPGPPTGPVVISDIT------- 20278 Query: 617 RVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGL 674 + SV ++W+ PK++ + Y + T +W + + V L Sbjct: 20279 --------EESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS-ATVARTMMKVMKL 20329 Query: 675 TTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVP 734 TTGE+Y FR+KA N G+S++ +S + V+ T P P + N S+T+GW P Sbjct: 20330 TTGEEYQFRIKAENRFGISDHI-DSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20388 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 +GGS ++GY+L+ ++ + W + N + T V ++ G +YEF++ A N AG+G Sbjct: 20389 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20448 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PS PSE + P ++ ++ S+ + W+ P + G S ++GY V+ R+ Sbjct: 20449 KPSHPSE----PVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL 20504 Query: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPV-------- 905 G W + T +S L Q Y FRV A NA G + PS+ P+ Sbjct: 20505 PDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGG 20564 Query: 906 -----------LVEARPGTK-EISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDD 953 +V+ R GT ++ AG+ + A W K +E+ + Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGK-------------PAPTIEWYKDDKELQTN 20611 Query: 954 ERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 +E D + + +K+ D+ + G Y + + + G +S+ + Sbjct: 20612 ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20653 Score = 191 bits (485), Expect = 4e-48 Identities = 214/857 (24%), Positives = 337/857 (39%), Gaps = 113/857 (13%) Query: 177 VQGFPTPVVQWYKDGSLI---CQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATN 233 V G P P ++W K+ ++I A + K + + L I +A +D TY+ A+N Sbjct: 9117 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASN 9176 Query: 234 AHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGE 293 G V N V E + P L ++ D++ E +T+ + Sbjct: 9177 RLGSVFRNVHV---------EVYDRPSPPRNLAVT--------DIK-AESCYLTWDAPLD 9218 Query: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLY 353 + T V + +AEW E ++ L + + + Sbjct: 9219 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRY------------GIWKLIPNGQYEF 9266 Query: 354 TLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 +R V++ G+SD V DP + G PG P L + ++V+W PP S Sbjct: 9267 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---RTKGSMLVSWTPPLDNGGS 9323 Query: 413 PVMGYFVDRCEVGTNNWVQCNDAPV-----KICKYPVTGLFEGRSYIFRVRAVNSAGISR 467 P+ GY++++ E G+ W + + AP+ K ++ V L EG Y FR A+N+AGI Sbjct: 9324 PITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGP 9383 Query: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527 PS SD A DP+ PGPP+ + +++ + Sbjct: 9384 PSEPSDPEVAGDPIF---------------------------PPGPPSCPEVKDKTKSSI 9416 Query: 528 VLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA-QTAVRSPRYAVFDLMEGKSYVFRV 585 L W+PP G P+ Y +E G+ W+RVN + + V +L E + Y FRV Sbjct: 9417 SLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRV 9476 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA---------SRNTKTSVVVQWDRPK 636 + N G SEPS+ T I A D+ P + A S+ +V+ PK Sbjct: 9477 KAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPK 9536 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV-----HGLTTGEQYIFRVKAVNAVG 691 + G G + N V+ TG+ + + A N G Sbjct: 9537 SSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK---YSITAKNKAG 9593 Query: 692 MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751 Q++ +V+ + VP P + + + S L WK+P GG I GY ++KR Sbjct: 9594 -----QKTANCRVKV-MDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT 9647 Query: 752 VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811 + K W +VN T + D L+E Y F++ A N GIG P + + P Sbjct: 9648 IDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYP 9706 Query: 812 EPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED-----AGEWITVNQTT 866 P P L + ++ + WK P G SPV+ Y V+ D W N+ Sbjct: 9707 -PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765 Query: 867 TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEIS----AGVDE 922 V DL +G Y FRV+AVNA GV KPS T P + I V+E Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9825 Query: 923 QGNIYLGFDCQEMTDASQFTWCK-------SYEEISDDERFKIETVGDHSKLYLKNPDKE 975 N+ + + + + TW K + E + D V D L + + Sbjct: 9826 GTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9884 Query: 976 DLGTYSVSVSDTDGVSS 992 D G Y+++ + G +S Sbjct: 9885 DTGLYTITAVNNLGTAS 9901 Score = 188 bits (478), Expect = 3e-47 Identities = 179/740 (24%), Positives = 304/740 (41%), Gaps = 121/740 (16%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 VQW ++ ++ Q K+++ S +H L+I D Y +A + + A Sbjct: 6637 VQWLRNNMVVVQG---DKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAA 6693 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 + D++ + + +G PL+ ++PY + Sbjct: 6694 APKIKTADQD----LVVDVGKPLTMVVPYDAYP--------------------------- 6722 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG-QASLSFSHLHKDDEGLYTLRIVSRGGV 363 + AEW++++ L TK Q S K D+G Y + + ++ G Sbjct: 6723 ------KAEAEWFKENEPLS----TKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6772 Query: 364 SDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 ++ L V D PG +L+ + V + W+ P T S ++GY V+R + Sbjct: 6773 AEGFINLKVIDV-------PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6825 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGR-SYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + WV D + C++ VTGL +G Y+FRV A N G P + V A D Sbjct: 6826 IKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYD 6884 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDP 541 VPGPP V ++++R V L+WEPP G + Sbjct: 6885 ---------------------------VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6917 Query: 542 LMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITS 601 Y IE S W A V D++EG+ Y FRV + NR G+ +PS T Sbjct: 6918 TNYVIELRDKTSIRWDTAMTVRA-EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6976 Query: 602 PIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPC 659 ++ D PS P + +S T++SV ++W+ P + +LGY ++ C G + W C Sbjct: 6977 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRC 7036 Query: 660 NHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ-----ESDVIKVQAALTVPSHP 714 N K + + V GL G +Y++RV A N G+S+ S+ +D V+ + + + Sbjct: 7037 NMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFK 7096 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNS-SPSKPTILTVD 773 G+ ++ + ++ VP P + + + + ++ + S +++ Sbjct: 7097 DGLEVIVPNPITIL----VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPS 7152 Query: 774 GLTEGSLYEFKI--------AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVR 825 ++ +Y K+ +++ I PS P E L F ++ Sbjct: 7153 ERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKE-----------------LKFGDIT 7195 Query: 826 DTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W+ P G SP++GY V+ RE W V T + V DL QGK Y+F Sbjct: 7196 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEF-TVPDLVQGKEYLF 7254 Query: 886 RVRAVNANGVGKPSDTSEPV 905 +V A N G G+P+ EPV Sbjct: 7255 KVCARNKCGPGEPAYVDEPV 7274 Score = 188 bits (477), Expect = 4e-47 Identities = 145/509 (28%), Positives = 233/509 (45%), Gaps = 82/509 (16%) Query: 371 FVRDADPLVTG----APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGT 426 FV ++ LV P P DL+ + ++ V +TW PP S ++ Y ++ +GT Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10455 Query: 427 NNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG------ISRPSRVSDAVAA--- 477 + + + + KY V GL EG +Y +RV AVN G ++P D +A Sbjct: 10456 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10515 Query: 478 ----LDPLDLRRLQAVHLEG-------------EKEIAIYQDDL---------------- 504 D L +R +A L G + E + +DD Sbjct: 10516 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10575 Query: 505 --------------------EGDAQV-----PGPPTG-VHASEISRNYVVLSWEPPTPRG 538 +G QV PGPP G V E++++Y+V+SW+PP G Sbjct: 10576 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10635 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 + Y IEK VG W V + +A + + V L+EGK Y+FR+ + N +G+S+P Sbjct: 10636 GSKITNYIIEKKEVGKDVWMPVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL 10693 Query: 598 EITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL 655 ++ ++A+D VP AP + + + TK S +V W++P H+ + + Y ++ + Sbjct: 10694 -VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKR 10751 Query: 656 WEPCNHKPIG-YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHP 714 W PI Y +F V L G QY FRV A N +G+ + S S + + + PS P Sbjct: 10752 WARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPP 10811 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTV 772 ++ +S+ L W+ P+ GGS ILGY ++ ++V + W N +P T V Sbjct: 10812 VNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKV 10871 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSE 801 GL +G Y+F++ AVN AG +P+ E Sbjct: 10872 TGLRDGQTYKFRVLAVNAAGESDPAHVPE 10900 Score = 187 bits (476), Expect = 5e-47 Identities = 190/783 (24%), Positives = 312/783 (39%), Gaps = 105/783 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + + V R +K+ +G P V W KDG + E + + S+ V + Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTL---KETTRVNVSSSKTVTS 19146 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I A +D TY +N+ G ++ ++V G P R + S P Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPP 19206 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + + + ++E + T W + Sbjct: 19207 EYDGGCQISNY-IVEKKETTSTT-------------------------------WHIVSQ 19234 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHD 393 + S+ L E + + +R G S +S V P PG P + Sbjct: 19235 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPF--SPPGPPGTPKVVH 19292 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 A + ++VTW+ P S V+GY ++ E + W + N + + V+GL EG Y Sbjct: 19293 ATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMY 19352 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 +RV A N AGI + S+ + V A DP D P Sbjct: 19353 EYRVYAENIAGIGKCSKSCEPVPARDPCD------------------------------P 19382 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + I+R V L W P G + Y +E+ + G W + N T ++ + V Sbjct: 19383 PGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCN-YTNIQETYFEV 19441 Query: 573 FDLMEGKSYVFRVLSAN-RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 +L E + Y FRV + N +SEPSE T PI +D P RV+ + +VV+ Sbjct: 19442 TELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKD----DVEPPRVMMDVKFRDVIVVK 19497 Query: 632 -WDRPKHEEDLLGY---YVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------Q 679 + K D+ G + G + E + I + H L T + Q Sbjct: 19498 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN---HTLLTVKDCIRRDTGQ 19554 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y+ +K N G + V+ P G+T C +L W P+ GG Sbjct: 19555 YVLTLK--NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKC-----SLSWGRPQEDGG 19607 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + I Y ++KRE H W + + T V L +G+ Y F++ VN G+GEP + Sbjct: 19608 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19666 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 + +T+P P + ++T V S+ + W P G S +SGY ++ RE+++ W Sbjct: 19667 VAIKALDPFTVPSPPTSLEIT--SVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRW 19724 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS------EPVLVEARPGT 913 + VN+ + +K + L++G Y +RV A NA G+ PS+TS +PV + + P Sbjct: 19725 VRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSK 19784 Query: 914 KEI 916 +I Sbjct: 19785 PKI 19787 Score = 187 bits (475), Expect = 6e-47 Identities = 180/671 (26%), Positives = 294/671 (43%), Gaps = 73/671 (10%) Query: 349 DEGL-YTLR-----IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIV 401 DEGL Y + IV G S S RD DP PG P + R+ V + Sbjct: 18265 DEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP-----PGRPEAIVI---TRNNVTL 18316 Query: 402 TWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVN 461 WK P S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N Sbjct: 18317 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18376 Query: 462 SAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD---LEGDAQVPGPPTGV 517 +AG S PS S A+ A D +D ++ + + I ++ + LE D + P V Sbjct: 18377 AAGNFSEPSDSSGAITARDEIDAPNA-SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV 18435 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM- 576 + + GK+ +E++ R+ ++ ++ V D + Sbjct: 18436 WSKD----------------GKE-----LEETAA------RMEIKSTIQKTTLVVKDCIR 18468 Query: 577 -EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRP 635 +G Y+ ++ + G ++ IT ++ D P P +V T + W+ P Sbjct: 18469 TDGGQYILKLSNV---GGTKSIPIT--VKVLDRPGPPEGPLKVTGV--TAEKCYLAWNPP 18521 Query: 636 KHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMS 693 + ++ Y ++ W + + N + V L G +YIFRV AVN G+ Sbjct: 18522 LQDGGANISHYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIG 18580 Query: 694 ENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 E ES + P P + SM + W P GG+ I GY L+KR+ Sbjct: 18581 E-PLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKE 18639 Query: 754 HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPE 812 W + N L V GLTEG YEF++AA N AG+GEPS+PS ++ C+A + Sbjct: 18640 GVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA--LYP 18697 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTT-TANRY 871 PGP + + +S+ + W P+Y G +PV GY V+ +E A EW T T + Sbjct: 18698 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18757 Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLG-- 929 V+ L++ Y FR+ A+N+ GVG+P+ V+ + R EI D + + L Sbjct: 18758 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18817 Query: 930 -----FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 F + + W K+ ++D R +IE + L + N + D G Y++++ Sbjct: 18818 ATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 18875 Query: 985 SDTDGVSSSFV 995 + G ++FV Sbjct: 18876 ENNSGSKTAFV 18886 Score = 187 bits (474), Expect = 8e-47 Identities = 169/652 (25%), Positives = 277/652 (42%), Gaps = 58/652 (8%) Query: 357 IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 IV G S S RD DP PG P + R+ V + WK P S + Sbjct: 16115 IVGIGKPSKVSECYVARDPCDP-----PGRP---EAIIVTRNSVTLQWKKPTYDGGSKIT 16166 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI-SRPSRVSDA 474 GY V++ E+ W++ + + + VTGL E Y FRV A N+AG+ S PS + A Sbjct: 16167 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16226 Query: 475 VAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPP 534 + A D +D R+ + + + + DA + G P + W Sbjct: 16227 ITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-----------IQWI-- 16273 Query: 535 TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLS 594 +G L + + ++ + AVR ++ +Y+ + + ++ Sbjct: 16274 --KGDQELSNTARLEIKSTDFATSLSVKDAVR---------VDSGNYILKAKN-----VA 16317 Query: 595 EPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAG 652 +T ++ D P P V+ S T + W P + D++ Y V+ Sbjct: 16318 GERSVTVNVKVLDRPGPPEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETS 16375 Query: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712 +W + + V L G +Y FR+ AVN G+ E ES+ + + VP Sbjct: 16376 RLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE-PLESEPVVAKNPFVVPD 16433 Query: 713 HPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 P + SM + W+ P GGS ILGY L+KR+ W + L V Sbjct: 16434 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16493 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVM 831 GL E YEF+++A N AG+ EPS PS + K C+ + +PGP + ++ +S+ + Sbjct: 16494 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDITRSSVFL 16551 Query: 832 LWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKTYVFRVRAV 890 W P+Y G + GY V+ + GEW T N+ ++V L + Y FR+ A+ Sbjct: 16552 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 16611 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG--NIYLG-----FDCQEMTDASQFTW 943 N GVG+ +D P++VE + +I ++ + NI G F + + W Sbjct: 16612 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16671 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 K EI D I+ + L L N ++ D G Y++++ ++ G S+FV Sbjct: 16672 GKVDGEIRD--AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 16721 Score = 186 bits (473), Expect = 1e-46 Identities = 191/764 (25%), Positives = 296/764 (38%), Gaps = 106/764 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++ S++V +K+ + G P P + W KDG + Q + + + + T Sbjct: 16925 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT---RINVTDSLDLTT 16981 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I DD Y N GQ + + +V + P P Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTASIEIVT----------------LDKPDPPKGPV 17025 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 DV E++TL + ++ RD + W + Sbjct: 17026 KFDDV------------SAESITLSWNPPLYTGGCQITNYIVQKRDTT---TTVWDVVSA 17070 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-------GAPGAP 386 + +L + L E + + +R G S F ++DP+V G PG P Sbjct: 17071 TVARTTLKVTKLKTGTEYQFRIFAENRYGQS------FALESDPIVAQYPYKEPGPPGTP 17124 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 ++D +++ W P SPV+GY ++R E + W + N + ++ Sbjct: 17125 F---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN 17181 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L EG Y FRV A N G+ + S+ S+ A DP D Sbjct: 17182 LEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD------------------------ 17217 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAV 565 PG P + + RN + L W P G + Y +EK + G W + + T V Sbjct: 17218 ---PPGTPEPI---MVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF-TNV 17270 Query: 566 RSPRYAVFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 ++ V L E + Y FRV++ N G +S+PS+ T PI A+D +P R+ Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP----RISMDPKF 17326 Query: 625 KTSVVVQ-WDRPKHEEDLLGYYVDCC--VAGTNLWEP---CNHKPIGYNRFVVHG---LT 675 + ++VV + + E D+ G + + G E C K + ++ Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17386 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G QYI R A N G V+ P G+T C +L W P Sbjct: 17387 DGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC-----SLTWSPPL 17439 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I Y ++KRE W V +S L V L EG+ Y F+I AVN G+GE Sbjct: 17440 QDGGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17498 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + + + PGP L + S+ + W P G S + GY V+ R+ Sbjct: 17499 PLESAPVLMKNPFVL--PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRS 17556 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPS 899 WI N+ + L+V+ L + Y FRV A NA GVG+PS Sbjct: 17557 GIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17600 Score = 186 bits (471), Expect = 2e-46 Identities = 169/660 (25%), Positives = 282/660 (42%), Gaps = 64/660 (9%) Query: 352 LYTLRIVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 +Y IV G S +S RD DP PG P + R+ + + W P Sbjct: 17192 VYAENIVGVGKASKNSECYVARDPCDP-----PGTPEPIM---VKRNEITLQWTKPVYDG 17243 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPS 469 S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N+AG IS+PS Sbjct: 17244 GSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17303 Query: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529 + + A D ++L R+ + + + +A V G P + Sbjct: 17304 DSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT-----------I 17352 Query: 530 SWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W RG + + + + + A+R ++G Y+ R + Sbjct: 17353 EWL----RGDKEIEESARCEIKNTDFKALLIVKDAIR---------IDGGQYILRASN-- 17397 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 ++ ++ D P P +V + K S+ W P + D+ Y V+ Sbjct: 17398 ---VAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT--WSPPLQDGGSDISHYVVE 17452 Query: 648 CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707 W + + N V L G +Y+FR+ AVN G+ E + + V+ ++ Sbjct: 17453 KRETSRLAWTVVASEVVT-NSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL-MKNP 17510 Query: 708 LTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP 767 +P P + + N SMT+ W P GGS I+GY ++KR+ W + N Sbjct: 17511 FVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD 17570 Query: 768 TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRD 826 L V GLTE YEF+++A N AG+GEPS + ++K C+ + +PGP + + Sbjct: 17571 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD--PVFKPGPPTNAHIVDTTK 17628 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW-ITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W P+Y G S + GY V+ + D EW I QT ++S L + + Y Sbjct: 17629 NSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKI 17688 Query: 886 RVRAVNANGVG---------KPSDTSE-PVLVEARPGTKEISAGVDEQGNIYLGFDCQEM 935 RV A+N G+G KP D E P L K I I++ F + Sbjct: 17689 RVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPF---KG 17745 Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + TW + E +D + +IE ++++L + N D+ D G Y + + ++ G S+FV Sbjct: 17746 RPTPEITWSREEGEFTD--KVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17803 Score = 186 bits (471), Expect = 2e-46 Identities = 189/804 (23%), Positives = 332/804 (41%), Gaps = 87/804 (10%) Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP-IGLPLSSMIPYTHFDVQFLEKFG 285 + A NA G +S + VV G S G P I LPL YT Sbjct: 20535 FRVFARNAVGSISNPSEVV-----GPITCIDSYGGPVIDLPLE----YTE---------- 20575 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHL 345 V R G +V L+ + P P EWY+DD L+ + + AS+ Sbjct: 20576 VVKYRAGTSVKLRAGISGKP-----APTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20630 Query: 346 HKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + + G Y L++ R + SA + V+ D G PG P++ + A + + + W+P Sbjct: 20631 DRLNSGCYELKL--RNAMGSASATIRVQILDK--PGPPGGPIEFKTVTAEK--ITLLWRP 20684 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + + Y V++ E W ++ ++ C T + +G YIFRVRAVN GI Sbjct: 20685 PADDGGAKITHYIVEKRETSRVVWSMVSEH-LEECIITTTKIIKGNEYIFRVRAVNKYGI 20743 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P SD+V A + PGPP ++I++N Sbjct: 20744 GEPLE-SDSVVAKNAF---------------------------VTPGPPGIPEVTKITKN 20775 Query: 526 YVVLSWEPP-TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 + + W P G D YF+EK S W +V +T +R R V L E Y +R Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET-IRDTRQKVTGLTENSDYQYR 20834 Query: 585 VLSANRHG---LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--E 639 V + N G SEPSE +A D P P ++ + +TK+S+ + W +P ++ Sbjct: 20835 VCAVNAAGQGPFSEPSEF---YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGS 20891 Query: 640 DLLGYYVDCCVAGTNLWEPCNHK-PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 + GY V+ W + K + +VV L G Y FRV AVN G E + Sbjct: 20892 AVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM 20951 Query: 699 SDVIKVQAALTVPSHPYGITL----LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 ++ ++ + L P + L + G + + +P P + + D++ + Sbjct: 20952 NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV--LIPFKGRPPPTVTWRKDEKNLGS 21009 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 + + ++ S ++LT+ +T ++ + N G+GEP + K + P Sbjct: 21010 DARYSIENTDSS-SLLTIPQVTRNDTGKYILTIEN--GVGEPKSSTVSVK----VLDTPA 21062 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 L V ++ +LW P+ G SP+ Y ++ R+ W V+ ++ + K+ Sbjct: 21063 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSF-KL 21121 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPG-TKEISAGVDEQGNIYLGFDCQ 933 DL + + FRV A N G+G+P +T+EPV P +++S + ++ L + Sbjct: 21122 IDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKP 21181 Query: 934 EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993 + S T + ++ + + ++ + ++ + + V + G+S Sbjct: 21182 DFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 21241 Query: 994 FVLDPEELERLMALSNEIKNPTIP 1017 + P ++ L+ ++ E+ IP Sbjct: 21242 VTIGPITVKELI-ITPEVDLSDIP 21264 Score = 185 bits (470), Expect = 2e-46 Identities = 164/638 (25%), Positives = 263/638 (41%), Gaps = 91/638 (14%) Query: 381 GAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC 440 G PG P + + ++ V+WK P S + GY V+R E + WV+ PV Sbjct: 14265 GPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDL 14324 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 + VTGL EG +Y FRV A N AGI PS SD+V D Sbjct: 14325 RCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA-------------------- 14364 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 A PGPP+ H ++ ++ L+W +P G + Y +E VG +W + Sbjct: 14365 -------AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14417 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGR 617 TA+R ++ V DL + Y FR+ + N G+ EP+ I DV +V AP Sbjct: 14418 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIP------DVEIVEREMAPDF 14471 Query: 618 VLASRNTKTSVVVQW----------DRPKHE----EDLLGYYVDCCVAGTNLWE-----P 658 L + +T VV RP E +D + + T + Sbjct: 14472 ELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPE 14531 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT 718 CN G + + V+ ++ G N + +D+ K Sbjct: 14532 CNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK--------------- 14576 Query: 719 LLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 S+TL W +P GGS I Y ++KRE K++ + K T V GL+EG Sbjct: 14577 ------DSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLSEG 14629 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 Y F++ A N GIGEP++ +E K P P L ++ +++ + W P + Sbjct: 14630 CEYFFRVMAENEYGIGEPTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKH 14685 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G S ++GY ++ + + + +W + TT V +L +G+ Y F+V AVN+ G P Sbjct: 14686 DGGSKITGYVIEAQRKGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14743 Query: 899 SDTSEPVLVEARPGTKEISA-GVDEQGNIYLGFDCQEMT------DASQFTWCKSYEEIS 951 + S PV+V+ + E+ G+ ++ I D ++ TW K + + Sbjct: 14744 RE-SRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK 14802 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 +R ET + L + + D G Y ++ + G Sbjct: 14803 QTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG 14840 Score = 185 bits (470), Expect = 2e-46 Identities = 164/623 (26%), Positives = 257/623 (41%), Gaps = 58/623 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P + D R+ V ++W+ P S ++GY V+ G++ W C A VK+ + Sbjct: 15744 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEA 15801 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 +TGL +G Y FRV A N GIS P ++S V A D L A L + + Sbjct: 15802 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---LVIPPAFKLLFNTFTVLAGE 15858 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQ 562 DL+ D G PT ++W K V RVNA+ Sbjct: 15859 DLKVDVPFIGRPTPA-----------VTWH---------------KDNVPLKQTTRVNAE 15892 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PSAP-GRVL 619 + + + D + V N G I+ +V V+ P P G V Sbjct: 15893 STENNSLLTIKDACREDVGHYVVKLTNSAG--------EAIETLNVIVLDKPGPPTGPVK 15944 Query: 620 ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTG 677 T S+ + W PK++ + Y V+ T W+ + + L TG Sbjct: 15945 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-ATVARTTIKACRLKTG 16003 Query: 678 EQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFS 737 +Y FR+ A N G S + Q VP P + SM + W P Sbjct: 16004 CEYQFRIAAENRYGKSTYLNSEPTV-AQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISD 16062 Query: 738 GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPS 797 GGS ++GY+L+++E + W ++N +P T GL EG YEF+++A N+ GIG+PS Sbjct: 16063 GGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPS 16122 Query: 798 DPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAG 857 SE + P P + V S+ + WK P Y G S ++GY V+ +E G Sbjct: 16123 KVSECYVARDPCDPPGRPEAII----VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 16178 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLVEARPGTKEI 916 W+ + T + + +V+ L + Y FRV A NA GV +PS+++ + I Sbjct: 16179 RWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRI 16238 Query: 917 SAGVDEQGNIYLGFDCQEMTDASQF-------TWCKSYEEISDDERFKIETVGDHSKLYL 969 S + I + DA + W K +E+S+ R +I++ + L + Sbjct: 16239 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298 Query: 970 KNPDKEDLGTYSVSVSDTDGVSS 992 K+ + D G Y + + G S Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERS 16321 Score = 185 bits (469), Expect = 3e-46 Identities = 198/834 (23%), Positives = 347/834 (41%), Gaps = 94/834 (11%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +++L ++G P P V W K+ P K RI+ LEI A +D YS Sbjct: 10930 TLRLSAIIKGVPFPKVTWKKE-----DRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10984 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 N G + + V+V ++P G P L +S + R Sbjct: 10985 TVENPAGSKTVSVKVLVL-----DKP----GPPRDLEVSEI------------------R 11017 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 ++ +T K + D V R DV ++W+ + + S HL++ + Sbjct: 11018 KDSCYLTWKEPL---DDGGSVITNYVVERRDVA--SAQWSPLSATSKKKSHFAKHLNEGN 11072 Query: 350 EGLYTLRIVSRGGVSDHSAFLF----VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + L+ + ++ G F+ ++ DPL PG P DL D ++ V + W Sbjct: 11073 QYLFRVAAENQYG---RGPFVETPKPIKALDPL--HPPGPPKDLHHVDVDKTEVSLVWNK 11127 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P+ SP+ GY V+ E GT +W++ C VTGL +G++Y FRV+A N G+ Sbjct: 11128 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV--VTGLQQGKTYRFRVKAENIVGL 11185 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P P++ + + V E ++ + +EG G T V I R Sbjct: 11186 GLPDTTI-------PIECQE-KLVPPSVELDVKL----IEGLVVKAG--TTVRFPAIIRG 11231 Query: 526 YVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRV 585 P P K + + S + + + +T S + + + + +++ Sbjct: 11232 V-------PVPTAK----WTTDGSEIKTD--EHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643 +N G + + DV P+ P +L T + + W PK + ++ Sbjct: 11279 TVSNAAG---SKTVAVHLTVLDVPGPPTGPINILDV--TPEHMTISWQPPKDDGGSPVIN 11333 Query: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 Y V+ + W + + H L G +Y+FRV+A N +G+ + + Sbjct: 11334 YIVEKQDTRKDTWGVVSSGSSKTKLKIPH-LQKGCEYVFRVRAENKIGVGPPLDSTPTV- 11391 Query: 704 VQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + + PS P + + ++ T+ W +PK GGSPI GYY+++REV K W VN + Sbjct: 11392 AKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVNKT 11450 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 P V GL EG+ YEF++ A NLAG+ +PS S+ K P PGP + + Sbjct: 11451 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKP-PGPPINPKLKD 11509 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKT 882 + ++W P+ G SP+ GY V+ ++ +W +N+ + +V L +G Sbjct: 11510 KSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNE 11569 Query: 883 YVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNIYLGFDCQEMTDAS- 939 Y FR++A N G G+P + +E V+ + P E+ + + +G + + Sbjct: 11570 YRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKG 11629 Query: 940 ----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 TW K + + ++R + +L +K + D G Y +S ++ G Sbjct: 11630 RPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11683 Score = 185 bits (469), Expect = 3e-46 Identities = 204/870 (23%), Positives = 337/870 (38%), Gaps = 134/870 (15%) Query: 161 RSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 ++H V S++L QG PTP W K S + A+ I + TL + + Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHTTDSFSTLTVENCN 22114 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFR-------SVGLPIGLPLSSMIPY 273 +D Y+ N G S V V G P S L PL Sbjct: 22115 RNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGAR 22174 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 H V +EK + RR + ++ KCT + Sbjct: 22175 IHHYV--VEKREAS-RRSWQVISEKCTRQI------------------------------ 22201 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV-TGAPGAPMDLQCH 392 + L + + + V+ GV + +P+V T P P L Sbjct: 22202 ------FKVNDLAEGVPYYFRVSAVNEYGVGEPYEM-----PEPIVATEQPAPPRRLDVV 22250 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 D ++ ++ W P+ S + GY ++ + G++ WV+ K + V L E Sbjct: 22251 DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTFTVERLVEKTE 22308 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y FRV+A N AG S P +V +P +E ++ + L G Sbjct: 22309 YEFRVKAKNDAGYSEPREAFSSVIIKEP---------QIEPTADLTGITNQLI--TCKAG 22357 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + R ++W+ R K+ RV+ T V Sbjct: 22358 SPFTIDVPISGRPAPKVTWKLEEMRLKET---------------DRVSITTTKDRTTLTV 22402 Query: 573 FDLMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 D M G S + + N G + P +T PI+ V+ Sbjct: 22403 KDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSA------------ 22450 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 S V+ W PK ++ Y V+ +GT W+ N + + V LT +Y Sbjct: 22451 ---ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEY 22506 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 FRV + N G+S+ + + +I + PS P + + ++M++ W+ P GGS Sbjct: 22507 SFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGS 22565 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I+GY+++K+E + W + N P V GL EG Y+F+ A+N AG+ + S+ S Sbjct: 22566 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 22625 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFR---EEDAG 857 + + PG +V +++ ++W AP Y G S V GY ++ + E G Sbjct: 22626 RPIMAQN-PVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 22681 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLV--EARPGTK 914 W+ N T ++ + V+ L +G TY FRV A NA GV K S+++ PV E P Sbjct: 22682 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 22741 Query: 915 EISAGV-DEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 E+ A + + I G D + DA+ + W K +E+ E+ ++ G + Sbjct: 22742 ELDARLHGDLVTIRAGSDL--VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT 22799 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFVL 996 +K D+ D G Y+++V + G + V+ Sbjct: 22800 AVIKFCDRSDSGKYTLTVKNASGTKAVSVM 22829 Score = 184 bits (466), Expect = 7e-46 Identities = 162/629 (25%), Positives = 274/629 (43%), Gaps = 63/629 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG +DL+ ++ + WK P++ S ++GY VD N W + + +Y Sbjct: 13579 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKS--LSLQY 13635 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVS----DAVAALDPLDLRRLQAVHLEGEKEIA 498 L EG+ Y FRV A N G PS ++ D V A D LDL+ L + Sbjct: 13636 SAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPD-LDLKGLPDL--------- 13685 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 Y + ++ P G A +S W+ +G+DPL + R Sbjct: 13686 CYLAKENSNFRLKIPIKGKPAPSVS-------WK----KGEDPL-----------ATDTR 13723 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V+ +++ + V+D + + + + N G E T I+ +P+ P + Sbjct: 13724 VSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG---TISIKVVGKPGIPTGP--I 13778 Query: 619 LASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTT 676 T ++ ++W PK + ++ Y ++ + N W C + F V L Sbjct: 13779 KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCA-SAVQKTTFRVTRLHE 13837 Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +Y FRV A N G+ E + S+ I + VP P +++ S++L W PK Sbjct: 13838 GMEYTFRVSAENKYGVGEGLK-SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKK 13896 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 +GGSPI GY+L+ +E + W N +P + V GLTEG YEF++ A+NLAG+G+P Sbjct: 13897 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13956 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S PSE + P + S+ ++W P Y G ++GY V+ R+ + Sbjct: 13957 SLPSE----PVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPS 14012 Query: 857 GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVN-ANGVGKPSDTSEPVLV--EARPGT 913 W+ N V+DL +G Y FR+RA N A + PS+++E ++ E T Sbjct: 14013 KSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPT 14072 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 + + + I G D + S + +W K+ ++I + +I + S Sbjct: 14073 IVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 14131 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 L +K ++D G Y+++ ++ G V Sbjct: 14132 LTIKYATRKDAGEYTITATNPFGTKVEHV 14160 Score = 184 bits (466), Expect = 7e-46 Identities = 157/633 (24%), Positives = 259/633 (40%), Gaps = 56/633 (8%) Query: 283 KFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSF 342 K G+T + G+T+ L ++ L P++ W + ++ S T++ + L+ Sbjct: 14080 KDGLTIKA-GDTIVLNAISILGKPL----PKSSWSKAGKDIRPSDITQITSTPTSSMLTI 14134 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + + D G YT+ + G V V PG P ++ + + + +T Sbjct: 14135 KYATRKDAGEYTITATNPFGTK-------VEHVKVTVLDVPGPPGPVEISNVSAEKATLT 14187 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W PP SP+ Y +++ E W ++ ++ C++ T L +G YIFRV AVN Sbjct: 14188 WTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNH 14246 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 G P + S+ V +D PGPP S + Sbjct: 14247 YGKGEPVQ-SEPVKMVDRFG---------------------------PPGPPEKPEVSNV 14278 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 ++N +SW+ P G + Y +E+ S W R +T V R V L EG +Y Sbjct: 14279 TKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTY 14337 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE-- 639 FRV + NR G+ PSE + + +D P P + TK S + W +P ++ Sbjct: 14338 EFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGL 14397 Query: 640 DLLGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 ++ GY V+ G W + + +FVV L T E+Y FR+ A+N G+ E + Sbjct: 14398 EITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14457 Query: 699 SDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWH 758 DV V+ + P L L ++ G P K ++ KN Sbjct: 14458 PDVEIVEREM-APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRA 14516 Query: 759 EVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818 + ++ S T+L + +F + N AG + + PGP + Sbjct: 14517 NIENTESF-TLLIIPECNRYDTGKFVMTIENPAG-------KKSGFVNVRVLDTPGPVLN 14568 Query: 819 LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQ 878 L ++ S+ + W P+ G S ++ Y V+ RE + T Y KV+ L Sbjct: 14569 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLS 14627 Query: 879 QGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP 911 +G Y FRV A N G+G+P++T+EPV P Sbjct: 14628 EGCEYFFRVMAENEYGIGEPTETTEPVKASEAP 14660 Score = 184 bits (466), Expect = 7e-46 Identities = 233/952 (24%), Positives = 374/952 (39%), Gaps = 107/952 (11%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR---CEVGTNNWVQCNDAPVK 438 APG P + D R V + W P S V+GY ++R EVG W++CN V Sbjct: 22636 APGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22692 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQA-VHLEGEKE 496 + VT L EG +Y FRV A N+AG IS+ S + V D + + L G+ Sbjct: 22693 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22752 Query: 497 IAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK-DPLMYFIEKSVVGSGS 555 DL DA V G P EP K D + EK Sbjct: 22753 TIRAGSDLVLDAAVGGKP-----------------EPKIIWTKGDKELDLCEK------- 22788 Query: 556 WQRVNAQ-TAVRSPRYAVF-DLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS 613 V+ Q T R+ F D + Y V +A+ G S + + + P Sbjct: 22789 ---VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNAS--GTKAVSVMVKVLDS------PG 22837 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV 671 G++ SR T+ + W P+ + ++ Y V+ W + + +VV Sbjct: 22838 PCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVV 22896 Query: 672 HGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGW 731 L +YIFRV+AVN G ES+ I + + T+PS P + + + W Sbjct: 22897 TRLIKNNEYIFRVRAVNKYGPGV-PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQW 22955 Query: 732 KVPKFSGGSPILGYYLDKREVHHKNWHEVNSS-PSKPTILTVDGLTEGSLYEFKIAAVNL 790 P+ GG+ I Y +DKRE W VN T L V L EG Y+F++ AVN Sbjct: 22956 TKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNA 23015 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 AG EPS+ S C + PGP + S+ + W P+Y G + + GY ++ Sbjct: 23016 AGNSEPSEASNFISCREPSYT-PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 23074 Query: 851 FREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT---SEPVL 906 +E+D +W V+ T N V DL+ G+ Y FRV AVN G+ + S++ EPV Sbjct: 23075 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 23134 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETV 961 P E++ + + I G + M S TW K +++ R I+T Sbjct: 23135 RIEIPDL-ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTT 23191 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSE 1021 +S L + ++ D G Y++ + G S+ VL ++ + P S Sbjct: 23192 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL------------VKVYDTPGPCPSV 23239 Query: 1022 LAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRI--KCDKA----TGIIEM 1075 E+ W +I+ RE + + KC K +G++E Sbjct: 23240 KVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEG 23299 Query: 1076 VMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEY 1135 M F + E Y + G+ S VL+ + L A+ + + + Sbjct: 23300 TMYYFRVLPENIYGI----GEPCETSDAVLVSE---VPLVPAKLEVVDVTKS-----TVT 23347 Query: 1136 LHWD-VTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKD 1194 L W+ + RL V K +W+K + L+ + E + L++ + Sbjct: 23348 LAWEKPLYDGGSRLTGYVLEACKAGTERWMK---------VVTLKPTVLEHTVTSLNEGE 23398 Query: 1195 HGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMK 1254 ++ ++++G + D L + S P K + P G ++ + Sbjct: 23399 QYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTIDLSTMPQKTIHVPAGRPVELVIP 23456 Query: 1255 YF-TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEI 1305 +W +K+ SE + + ++A L I E T +D G+YT E+ Sbjct: 23457 IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23508 Score = 182 bits (462), Expect = 2e-45 Identities = 157/621 (25%), Positives = 254/621 (40%), Gaps = 75/621 (12%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 LV P R P A W+ L+ES+ + A L+ D G YTL + + Sbjct: 23453 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23512 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G + + + + D G P P+ + DA + ++W+PP +P+ GY V++ Sbjct: 23513 GTTSETIKVIILDKP----GPPTGPIKIDEIDATS--ITISWEPPELDGGAPLSGYVVEQ 23566 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 + W+ +++ + + T L EG Y+FRV A N GI Sbjct: 23567 RDAHRPGWLPVSESVTR-STFKFTRLTEGNEYVFRVAATNRFGIGS-------------- 23611 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 LQ+ +E I ++PGPP + ++SR+ + L+W PP G Sbjct: 23612 ---YLQSEVIECRSSI-----------RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ 23657 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ V + W RVN + V RY L EG Y RV + N G +PS + Sbjct: 23658 VTGYIVERKEVRADRWVRVN-KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23716 Query: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEP 658 PI A D P P + T+TSV + W P+ E + GY ++ + W Sbjct: 23717 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23776 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY--- 715 CN P + + L G +Y FRV A NA G E ++ +KV L P + Sbjct: 23777 CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDER 23836 Query: 716 ---GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 GI + +T+ K F PI + + +++ + + + ++ I Sbjct: 23837 YQEGIFVRQGGVIRLTIPIKGKPF----PICKWTKEGQDISKRAMIATSETHTELVIKEA 23892 Query: 773 DGLTEGSLYEF--------KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEV 824 D G+ Y+ K + + IG P+ P GP L + ++ Sbjct: 23893 DRGDSGT-YDLVLENKCGKKAVYIKVRVIGSPNSPE-------------GP---LEYDDI 23935 Query: 825 RDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 + S+ + W+ P G + + GY ++ RE W T++ L V L++ Y Sbjct: 23936 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTS-LVVKGLKENVEYH 23994 Query: 885 FRVRAVNANGVGKPSDTSEPV 905 FRV A N G+ KP + EPV Sbjct: 23995 FRVSAENQFGISKPLKSEEPV 24015 Score = 182 bits (461), Expect = 3e-45 Identities = 173/685 (25%), Positives = 271/685 (39%), Gaps = 56/685 (8%) Query: 238 VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS----SMIPYTHFDVQFLEKFGVTFRREGE 293 VS N V GD FR + +S S P T D K + R G+ Sbjct: 22691 VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 22750 Query: 294 TVTLKCTMLVTPDLK---RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 VT++ + D + +P+ W + D L + + + +A+ + D Sbjct: 22751 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22810 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G YTL + + G S + V D+ PG L ++ + W P Sbjct: 22811 GKYTLTVKNASGTKAVSVMVKVLDS-------PGPCGKLTVSRVTQEKCTLAWSLPQEDG 22863 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y V+R E NWV + Y VT L + YIFRVRAVN G Sbjct: 22864 GAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAVNKYG------ 22916 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 V +E E +A +P PP + ++++ Sbjct: 22917 ----------------PGVPVESEPIVA------RNSFTIPSPPGIPEEVGTGKEHIIIQ 22954 Query: 531 W-EPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W +P + G + Y ++K S W RVN V R V LMEG Y FRV + N Sbjct: 22955 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 23014 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G SEPSE ++ I ++ + P P TK S+ + W +P ++ D++GY ++ Sbjct: 23015 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 23074 Query: 648 CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 T+ W + + I F V L G++Y FRV AVN GMSE S+ I+ Sbjct: 23075 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 23134 Query: 707 ALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK 766 + +P L ++ G P K+ + + ++++ S Sbjct: 23135 RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY 23194 Query: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826 ++L VD + ++ I A N +G + PGP + EV Sbjct: 23195 -SLLIVDKVNRYDAGKYTIEAENQSG-------KKSATVLVKVYDTPGPCPSVKVKEVSR 23246 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFR 886 S+ + W+ P G +PV+ Y V+ RE + TV + Y ++S L +G Y FR Sbjct: 23247 DSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLY-RISGLVEGTMYYFR 23305 Query: 887 VRAVNANGVGKPSDTSEPVLVEARP 911 V N G+G+P +TS+ VLV P Sbjct: 23306 VLPENIYGIGEPCETSDAVLVSEVP 23330 Score = 181 bits (460), Expect = 4e-45 Identities = 159/669 (23%), Positives = 274/669 (40%), Gaps = 82/669 (12%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ PG P + + D R V + W P S V GY ++ +V + W +CN Sbjct: 23723 DPIAP--PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 23780 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR--RLQAVHLEG 493 P KI +Y +T L +G Y FRV A N+ G P+ V V + L+ L + EG Sbjct: 23781 PTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEG 23840 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGS 553 I + Q G ++ P G + + + W T G+D I K Sbjct: 23841 ---IFVRQG---GVIRLTIPIKG-------KPFPICKW---TKEGQD-----ISK----- 23874 Query: 554 GSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHG----------LSEPSEITSPI 603 R T+ + + G S + ++ N+ G + P+ P+ Sbjct: 23875 ----RAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23930 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 + D+ V SV V W P + D+LGY ++ W + Sbjct: 23931 EYDDIQV---------------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23975 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT-LL 720 + G + VV GL +Y FRV A N G+S+ + + + + L P P +L Sbjct: 23976 RVRGTS-LVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVL 24034 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + S++L W PK GGS + GYY++++E W N + T+ TV GL + Sbjct: 24035 DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAE 24094 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G+ E S SE C+ +P +L + S+ + W+ P G Sbjct: 24095 YQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSISKDSVTLQWEKPECDG 24153 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + GY+V++R+ W N+ ++ + L + Y FRV A N G+ +P Sbjct: 24154 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24213 Query: 901 TSEPVLVEARPG--------TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 T+ + + G K+++ + E + + + D W + +E+ Sbjct: 24214 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD---IKWYRFGKELIQ 24270 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 ++K+ + G L + ++ED G Y+ ++++ V + E +L+ + Sbjct: 24271 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGEVETSSKLLLQATPQF 24323 Query: 1013 NPTIPLKSE 1021 +P PLK + Sbjct: 24324 HPGYPLKEK 24332 Score = 179 bits (453), Expect = 2e-44 Identities = 155/603 (25%), Positives = 260/603 (43%), Gaps = 78/603 (12%) Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGA---- 382 +W ++ G L + E + +R V++ G S+ S +DP++ Sbjct: 7724 EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS-----EPSDPVLCREKLYP 7778 Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P L+ + ++ + W P SP+ Y V++ +V W Q D VK K Sbjct: 7779 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKC 7837 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 VT L EG Y+FRV A N+ G S + + D+V A D Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT-------------------- 7877 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA 561 PGPP + ++++ +V L WEPP G P+ Y IEK W + Sbjct: 7878 -------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG- 7929 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +TA + V D++EG F+V + N G+ PSE T + +D T PS P + + Sbjct: 7930 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 7989 Query: 622 RNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH-GLTTGE 678 + + + W P+ ++GY+V+ C GT W N +PI +F V G+ + Sbjct: 7990 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 8049 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQ---AALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +Y+ RV+AVNA+G+SE S+ S+ + + T+ + I ++ +G +++ VP Sbjct: 8050 EYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVI--EGEKLSI--PVPF 8105 Query: 736 FSGGSPILGYYLDKREVHH------KNWHEVNSSPSKPTILTVDGLTEGSLYEFKI---- 785 + P + ++ D +EV KN H +++ P + D E K+ Sbjct: 8106 RAVPVPTVSWHKDGKEVKASDRLTMKNDH-ISAHLEVPKSVRADAGIYTITLENKLGSAT 8164 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 A++N+ IG P GP D+ ++ +S + W+ P + G +P+ Sbjct: 8165 ASINVKVIGLP-----------------GPCKDIKASDITKSSCKLTWEPPEFDGGTPIL 8207 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE +I V + V DL Y FRV+AVN G G+ + PV Sbjct: 8208 HYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV 8266 Query: 906 LVE 908 + + Sbjct: 8267 IAQ 8269 Score = 177 bits (450), Expect = 5e-44 Identities = 166/627 (26%), Positives = 257/627 (40%), Gaps = 66/627 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK- 441 PG P + D + V + W P S ++GYFV+ C++ + WV+CN AP +I + Sbjct: 12888 PGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12944 Query: 442 -YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 Y TGL E Y FR A + IS PS SD V L A ++ ++++ Sbjct: 12945 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL---------AENVPPRIDLSVA 12995 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVN 560 L G + A+ + +SW+ KD + K G + N Sbjct: 12996 MKSLL--TVKAGTNVCLDATVFGKPMPTVSWK------KDGTLL---KPAEGIKMAMQRN 13044 Query: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 T +F + S + + + N G T ++ D P P V Sbjct: 13045 LCTL------ELFSVNRKDSGDYTITAENSSG---SKSATIKLKVLDK---PGPPASVKI 13092 Query: 621 SRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 ++ ++ W+ P + ++ Y VD W + + V L G Sbjct: 13093 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVS-ATVPITSCSVEKLIEGH 13151 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI----TLLNCDGHSMTLGWKVP 734 +Y FR+ A N G+ + V A P P G + N MT+ WK P Sbjct: 13152 EYQFRICAENKYGVGD-----PVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPP 13206 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 GGSPI GY L+KRE NW +VN P L GL EG+ YEF++ A+N AG G Sbjct: 13207 ADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPG 13266 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PSD S+ P PA+ + R +S+ + W P Y G SP+ GY V+ + Sbjct: 13267 KPSDASKAAYARDPQYPPGPPAFPKVYDTTR-SSVSLSWGKPAYDGGSPIIGYLVEVKRA 13325 Query: 855 DAGEWITVN--QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLV 907 D+ W+ N Q R+ +V+ L + Y FRV AVN G PSD + +L+ Sbjct: 13326 DSDNWVRCNLPQNLQKTRF-EVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13384 Query: 908 EARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVG 962 P E+ A + + + G + + TW K + D I++ Sbjct: 13385 ---PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD 13441 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L +N +K D G Y +++ ++ G Sbjct: 13442 FDTFLRCENVNKYDAGKYILTLENSCG 13468 Score = 176 bits (445), Expect = 2e-43 Identities = 164/628 (26%), Positives = 264/628 (42%), Gaps = 59/628 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + + R+ V + W P + GY V++ ++ + +W++ N V C + Sbjct: 13972 PGKP---EVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAF 14028 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 VT L EG Y FR+RA N+AG IS PS ++ + D E E + Sbjct: 14029 TVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD------------EYEAPTIVLD 14076 Query: 502 DDLEGDAQVPGPPTGV--HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 ++ + T V S + + SW + GKD I + + + + + Sbjct: 14077 PTIKDGLTIKAGDTIVLNAISILGKPLPKSSW---SKAGKDIRPSDITQ-ITSTPTSSML 14132 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV--VPSAPGR 617 + A R A + ++ + + ++ VTV VP PG Sbjct: 14133 TIKYATRK-------------------DAGEYTITATNPFGTKVEHVKVTVLDVPGPPGP 14173 Query: 618 VLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLT 675 V S + + W P + + Y ++ LW + + I R V L Sbjct: 14174 VEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLI 14232 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G +YIFRV AVN G E Q S+ +K+ P P + N ++ T+ WK P Sbjct: 14233 QGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14291 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I GY++++RE W +P V GL EGS YEF+++A N AGIG Sbjct: 14292 DDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGP 14351 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 PS+ S+ + P PGP + + S + W P Y G ++GY V+ ++ Sbjct: 14352 PSEASDSVLMKDAAYP-PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14410 Query: 856 AGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGT 913 WI + T TA R + V DLQ + Y FR+ A+N GVG+P+ + +VE Sbjct: 14411 DEAWIK-DTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAP 14469 Query: 914 K-EISAGVDEQGNIYLGFDCQ-----EMTDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 E+ A + + G + + A + TW K + I+ R IE + L Sbjct: 14470 DFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLL 14527 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ D G + +++ + G S FV Sbjct: 14528 IIPECNRYDTGKFVMTIENPAGKKSGFV 14555 Score = 174 bits (442), Expect = 4e-43 Identities = 154/640 (24%), Positives = 249/640 (38%), Gaps = 84/640 (13%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + +++ + V W PP + GYF+++ E + WV N + + + Sbjct: 12091 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 12150 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 V L Y FRV+A N GI PS S V A DP++ Sbjct: 12151 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE-------------------- 12190 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE-KSVVGSGS----W 556 PGPPT + +++ + L W P G P++ Y +E + + S W Sbjct: 12191 -------PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--- 613 +R NA + + V L E + Y FRV + N+ G+ P+E+ I+ +++ P Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303 Query: 614 -------------APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 P R+ A + + V W + + + VD L P + Sbjct: 12304 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNS 12363 Query: 661 HKPIGYNRFVVHGLTTGEQYIF-RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITL 719 + + GE+ +F V+ ++ G + + SDV K Sbjct: 12364 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT--------------- 12408 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGS 779 S + W P+ GGS + Y ++KRE K W V K T V L G+ Sbjct: 12409 ------SCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKK-TSFHVTNLVPGN 12461 Query: 780 LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYS 839 Y F++ AVN G G P+D + + EP P L E+ S + W P+ Sbjct: 12462 EYYFRVTAVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRD 12520 Query: 840 GSSPVSGYFVDFREED--AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G + + GY +REE+ A W + + L V+ L++GK Y FRV A NA GV Sbjct: 12521 GGAKIDGYITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSL 12578 Query: 898 PSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDA-----SQFTWCKSYEEISD 952 P + + EA+ + EQ I G + W K +E+ Sbjct: 12579 PREAEG--VYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVT 12636 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 + S L +K+ ++D G YS++ ++ G + Sbjct: 12637 SSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDT 12676 Score = 173 bits (439), Expect = 1e-42 Identities = 157/607 (25%), Positives = 254/607 (41%), Gaps = 62/607 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + + + S + + + L + + D G Y+L + G + Sbjct: 12623 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12682 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V DA G P P D+ D + D ++W P S + Y V++C+V +WV Sbjct: 12683 VMDAP----GPPQPPFDIS--DIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVT 12736 Query: 432 CNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490 + K C+ V L G+ YIFRVRA N GIS P Sbjct: 12737 ALASVTKTSCR--VGKLIPGQEYIFRVRAENRFGISEP---------------------- 12772 Query: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKS 549 L K +A + VP P ++++++ + ++W+ P G P++ Y IE+ Sbjct: 12773 LTSPKMVAQFPFG------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK 12826 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W + N T VRS Y L+EG Y FR+ + N+ G S PS+ T + A+ + Sbjct: 12827 ERNSLLWVKAN-DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MP 12884 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 V P PG+ TK++V + W RPKH+ ++GY+V+ C + W CN P I Sbjct: 12885 VDP--PGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12942 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC--- 722 + GL QY FR A AV +S S+ SD + + A P + + + Sbjct: 12943 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 13002 Query: 723 -DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781 G ++ L V F P + + D + ++ + T L + + Sbjct: 13003 KAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT-LELFSVNRKDSG 13059 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 ++ I A N +G S+ + + +PGP + ++ ++ W+ P+ G Sbjct: 13060 DYTITAENSSG-------SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 13112 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y VD RE W V+ T V L +G Y FR+ A N GVG P T Sbjct: 13113 SEITNYIVDKRETSRPNWAQVSATVPITS-CSVEKLIEGHEYQFRICAENKYGVGDPVFT 13171 Query: 902 SEPVLVE 908 EP + + Sbjct: 13172 -EPAIAK 13177 Score = 172 bits (437), Expect = 2e-42 Identities = 163/628 (25%), Positives = 259/628 (41%), Gaps = 61/628 (9%) Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQ-ASLSFSHLHKDDE 350 GET L+ + P P W +D L+E+ Q +L + D Sbjct: 18417 GETFVLEADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G Y L++ + GG + V D G P P+ + A + Y+ W PP Sbjct: 18472 GQYILKLSNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDG 18525 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y +++ E +W Q + V+ Y VT L G YIFRV AVN GI P Sbjct: 18526 GANISHYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE 18584 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 S V A +P + PGPP+ S I+++ +V++ Sbjct: 18585 -SGPVTACNPY---------------------------KPPGPPSTPEVSAITKDSMVVT 18616 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W P G + Y +EK W + N +T + R V L EG SY FRV + N Sbjct: 18617 WARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAEN 18675 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G+ EPSE + +A D P P + +++SV + W +P ++ + GY V+ Sbjct: 18676 AAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVE 18735 Query: 648 CCVAGTNLWEPCNHKPIGY--NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ 705 A + W C P G +F V L +Y FR+ A+N+ G+ E + + Q Sbjct: 18736 VKEAAADEWTTCT-PPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQ 18794 Query: 706 AALTVPSHPYGITLLNCD--GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + P L S TL V P + + + + + EV SS Sbjct: 18795 ERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS 18854 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 T+L +D +T + + N +G S+ + P +LT E Sbjct: 18855 ---FTMLVIDNVTRFDSGRYNLTLENNSG-------SKTAFVNVRVLDSPSAPVNLTIRE 18904 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTY 883 V+ S+ + W+ P+ G + ++ Y V+ RE + T+ T + ++ +LQ+G +Y Sbjct: 18905 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTF-RIENLQEGCSY 18963 Query: 884 VFRVRAVNANGVGKPSDTSEPVLVEARP 911 FRV A N G+G P++T+EPV V P Sbjct: 18964 YFRVLASNEYGIGLPAETTEPVKVSEPP 18991 Score = 172 bits (436), Expect = 2e-42 Identities = 149/603 (24%), Positives = 243/603 (40%), Gaps = 66/603 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R P W R++ + ++ G LS + ++D G Y L++ + G SA Sbjct: 17746 RPTPEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG--SKSA 17801 Query: 369 FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNN 428 F+ V+ D PG P +L + +D + W+PP + V Y +D+ E Sbjct: 17802 FVTVKVLD-----TPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17856 Query: 429 WVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488 + + K + V L EG Y FRV A N G+ P DAV A +P Sbjct: 17857 YANVSSKCSKT-SFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-------- 17907 Query: 489 VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE 547 P PP V +++S+ L WE P G ++ Y +E Sbjct: 17908 ----------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17945 Query: 548 KSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD 607 G+ W V + V L G+ Y FRV + N G S+P + P+ A+D Sbjct: 17946 MQPKGTEKWSIVAESKVCNA---VVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 18002 Query: 608 VTVVPSA-----PGRVLASRNTKTSV-VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH 661 +T+ PS + A + K + V+ RP + G L + Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN---------ISWVKDGEPLKQTTRV 18053 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLL 720 V + G + F V A + + E+ + V L P P G + Sbjct: 18054 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV---LEKPGPPVGPVRFD 18110 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + + W+ P ++GG I Y ++KR+ WH V+++ ++ TI + L G+ Sbjct: 18111 EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTE 18169 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G P D + EPGP + +++ W PV G Sbjct: 18170 YQFRIFAENRYGKSAPLDSKA--VIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG 18227 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + + GY ++ +E+++ W+ +N+T + K + L +G Y F+V A N G+GKPS Sbjct: 18228 GTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18287 Query: 901 TSE 903 SE Sbjct: 18288 VSE 18290 Score = 172 bits (435), Expect = 3e-42 Identities = 170/703 (24%), Positives = 284/703 (40%), Gaps = 123/703 (17%) Query: 353 YTLRIVSRG--GVSDHSA-FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTT 409 Y R+ + GV + S +F R D L PG P + + D +R V + W P Sbjct: 18667 YEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYD 18724 Query: 410 TESPVMGYFVDRCEVGTNNWVQCNDAP-VKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468 +PV GY V+ E + W C ++ ++ VT L E Y FR+ A+NS G+ P Sbjct: 18725 GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEP 18784 Query: 469 SRVSDAVAALDPL---------DLRRLQA----------VHLEGEKEIAIYQDDLEG--- 506 + + +V A + + DLR++ V ++G E + + EG Sbjct: 18785 ATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18844 Query: 507 -DAQV--------------------------------------------PGPPTGVHASE 521 AQ+ P P + E Sbjct: 18845 DRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18904 Query: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++ V LSWEPP G + Y +EK ++ + + + + +L EG S Sbjct: 18905 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT--FRIENLQEGCS 18962 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE-- 638 Y FRVL++N +G+ P+E T P++ V+ P PGRV T+ + ++W++P+ + Sbjct: 18963 YYFRVLASNEYGIGLPAETTEPVK---VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGG 19019 Query: 639 EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ- 697 + GY V+ G+ W C + + GLT GE+Y+FRV AVN G S+ Q Sbjct: 19020 SKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQL 19077 Query: 698 ----ESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 + I+++ ++ +P H + + L VP + + D + + Sbjct: 19078 GVPVIARDIEIKPSVELPFHTFNVKARE------QLKIDVPFKGRPQATVNWRKDGQTL- 19130 Query: 754 HKNWHEVNSSPSKP-TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE 812 K VN S SK T L++ ++ + +++ N AG S + Sbjct: 19131 -KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG-------SITVPITIIVLDR 19182 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872 PGP + EV S+ + W P Y G +S Y V+ +E + W V+Q A + Sbjct: 19183 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSI 19241 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLVEARPGTKEI----------- 916 K+ L G Y FRV A N G S++S P PGT ++ Sbjct: 19242 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVT 19301 Query: 917 -SAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958 V++ G+ +G+ E + S W K+ + + D + K+ Sbjct: 19302 WQVPVNDGGSRVIGYHL-EYKERSSILWSKANKILIADTQMKV 19343 Score = 171 bits (434), Expect = 4e-42 Identities = 161/542 (29%), Positives = 240/542 (44%), Gaps = 50/542 (9%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DPL G P +P L + + + + WK P + SP+ GY +++ ++ + N Sbjct: 8985 DPL--GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 9042 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 + V L E + Y FRV+AVN G S PS + V D + + + G+ Sbjct: 9043 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT 9102 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 + + A V G P + E S+N V+ E PT D L I K V Sbjct: 9103 IKVKAGEPVHIPADVTGLP--MPKIEWSKNETVI--EKPT----DALQ--ITKEEV---- 9148 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PS 613 R A+T + P+ + E K + V ++NR G S + V V PS Sbjct: 9149 -SRSEAKTELSIPK----AVREDKG-TYTVTASNRLG--------SVFRNVHVEVYDRPS 9194 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL--WEPCNHKPIGYNRF 669 P + + S + WD P ++ Y +D A WE + + R+ Sbjct: 9195 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAV-EKRY 9253 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 + L QY FRV+AVN G+S+ +SD + +Q +P P +L SM + Sbjct: 9254 GIWKLIPNGQYEFRVRAVNKYGISDEC-KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLV 9312 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSP-----SKPTILTVDGLTEGSLYEFK 784 W P +GGSPI GY+L+KRE W V+ +P K V L EG Y+F+ Sbjct: 9313 SWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFR 9372 Query: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844 A+N AGIG PS+PS+ P PGP + +S+ + WK P G SP+ Sbjct: 9373 AMAINAAGIGPPSEPSDPEVAGDPIFP-PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPI 9431 Query: 845 SGYFVDFREEDAGEWITVNQ----TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 GY V+ +EE +W VN+ TT V +L++ + Y FRV+AVN G +PSD Sbjct: 9432 KGYIVEMQEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEPSD 9489 Query: 901 TS 902 T+ Sbjct: 9490 TT 9491 Score = 171 bits (433), Expect = 5e-42 Identities = 165/648 (25%), Positives = 245/648 (37%), Gaps = 83/648 (12%) Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL--LKESKWTKMFFGEGQA 338 L+ GV + G+T+ L+ + P P W +D L S K+ + Sbjct: 11900 LKLSGVLTVKAGDTIRLEAGVRGKPF-----PEVAWTKDKDATDLTRSPRVKIDTRADSS 11954 Query: 339 SLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDY 398 S + + D G Y + + G FV A V PG +L+ D + D Sbjct: 11955 KFSLTKAKRSDGGKYVVTATNTAGS-------FVAYATVNVLDKPGPVRNLKIVDVSSDR 12007 Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 V W PP + Y +++CE W A V VT L EG YIFRVR Sbjct: 12008 CTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRLIEGNEYIFRVR 12066 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVH 518 A N G P+ +A + PG P Sbjct: 12067 AENKIGTGPPTESKPVIA----------------------------KTKYDKPGRPDPPE 12098 Query: 519 ASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLME 577 +++S+ + + W PP GK YF+EK S W VN ++A+ R V +L+ Sbjct: 12099 VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN-KSAIPERRMKVQNLLP 12157 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 Y FRV + N G+ EPS + P+ A+D P P TK S+ + W +P + Sbjct: 12158 DHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVY 12217 Query: 638 E--EDLLGYYVD-----CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 + ++GY V+ + W+ CN + F V L ++Y FRV A N Sbjct: 12218 DGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ 12277 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 VG+ ++ + IK + L P ++ K+ G PI + + + Sbjct: 12278 VGIGRPAELKEAIKPKEILEPPEIDLDASMR-----------KLVIVRAGCPIRLFAIVR 12326 Query: 750 -REVHHKNWHEVN----------SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 R W +V L + T ++ + VN AG Sbjct: 12327 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG------ 12380 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + PGP DL +V TS + W P G S V+ Y V+ RE D Sbjct: 12381 -EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKT 12439 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 W TV + V++L G Y FRV AVN G G P+D +PVL Sbjct: 12440 WSTVTPEVKKTSF-HVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVL 12486 Score = 171 bits (433), Expect = 5e-42 Identities = 160/655 (24%), Positives = 271/655 (41%), Gaps = 62/655 (9%) Query: 364 SDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC 422 +++ L + ADP+ V P P + D R+ V ++W P S ++ Y V+ Sbjct: 16806 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16865 Query: 423 EVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + W +C A VK + +T L +G Y+FRV AVN G S P ++ + A D + Sbjct: 16866 AKHSEKWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV- 16922 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL 542 + + + + Y + D ++ P +G R ++W Sbjct: 16923 ------IEPDVKPAFSSYSVQVGQDLKIEVPISG-------RPKPTITWT---------- 16959 Query: 543 MYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 K + R+N ++ ++ + + + + AN G + T+ Sbjct: 16960 -----KDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-----QKTAS 17009 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCN 660 I+ + G V + S+ + W+ P + + Y V T +W+ + Sbjct: 17010 IEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 17069 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 + V L TG +Y FR+ A N G S + ESD I Q P P Sbjct: 17070 -ATVARTTLKVTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPGPPGTPFAT 17127 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 SM + W P +GGSP++GY+L+++E + W +VN + T L EG Sbjct: 17128 AISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIE 17187 Query: 781 YEFKIAAVNLAGIGEPSDPSEHF----KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 YEF++ A N+ G+G+ S SE + C+ PEP V+ + + W P Sbjct: 17188 YEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEP--------IMVKRNEITLQWTKP 17239 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-V 895 VY G S ++GY V+ R+ G W+ + T VS L + + Y FRV A NA G + Sbjct: 17240 VYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAI 17299 Query: 896 GKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYE 948 KPSD++ P+ + IS + I + +A W + + Sbjct: 17300 SKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDK 17359 Query: 949 EISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EI + R +I+ + L +K+ + D G Y + S+ G S SF ++ + L+R Sbjct: 17360 EIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG-SKSFPVNVKVLDR 17413 Score = 170 bits (431), Expect = 8e-42 Identities = 168/685 (24%), Positives = 281/685 (41%), Gaps = 86/685 (12%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R +P W +D LK++ + L +KDD G YT+ + G + Sbjct: 18029 PVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 18088 Query: 365 DHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 + + V + PG P+ ++ + + D+V+++W+PP T + Y V++ + Sbjct: 18089 TENLSVIVLEK-------PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 18141 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDL 483 T W + A V +T L G Y FR+ A N G S P Sbjct: 18142 TTTTTWHMVS-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP--------------- 18185 Query: 484 RRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM 543 L+ + I Y + PGPP + IS++ +++ W P G ++ Sbjct: 18186 -------LDSKAVIVQYP------FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKII 18232 Query: 544 -YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 Y +E+ S W ++N +T ++ ++ L EG Y F+V + N G+ +PS+++ Sbjct: 18233 GYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSEC 18291 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCN 660 A+D P P ++ +RN +V ++W +P ++ + GY V+ W + Sbjct: 18292 FVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18348 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPS----HPY 715 + F V GL ++Y FRV A NA G SE S S I + + P+ Y Sbjct: 18349 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18408 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWH-EVNSSPSKPTILTV 772 ++ G + L + G PI + + D +E+ E+ S+ K T++ Sbjct: 18409 KDVIVVHAGETFVLEADI----RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVK 18464 Query: 773 DGL-TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 D + T+G Y K++ V G S P + PGP L V Sbjct: 18465 DCIRTDGGQYILKLSNVG----GTKSIP-----ITVKVLDRPGPPEGPLKVTGVTAEKCY 18515 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W P+ G + +S Y ++ RE W V+ A Y KV+ L G Y+FRV AV Sbjct: 18516 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY-KVTKLLPGNEYIFRVMAV 18574 Query: 891 NANGVGKPSDTS-----EPVLVEARPGTKEISA------------GVDEQGNIYLGFDCQ 933 N G+G+P ++ P P T E+SA VD+ G G+ Sbjct: 18575 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-IL 18633 Query: 934 EMTDASQFTWCKSYEEISDDERFKI 958 E D W K ++ D R ++ Sbjct: 18634 EKRDKEGVRWTKCNKKTLTDLRLRV 18658 Score = 169 bits (429), Expect = 1e-41 Identities = 139/511 (27%), Positives = 223/511 (43%), Gaps = 34/511 (6%) Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +YIFRV+AVN G+ E ESD + + A P P + +SMT+ W P Sbjct: 20728 GNEYIFRVRAVNKYGIGE-PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIA 20786 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 GGS I GY+L+KR+ W +V + T V GLTE S Y++++ AVN AG G Sbjct: 20787 DGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPF 20846 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S+PSE +K A + PGP + + +S+ + W PVY G S V+GY V+ R+ + Sbjct: 20847 SEPSEFYKA-ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE 20905 Query: 857 GEWITVNQ--TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTK 914 EW TV+ Y+ VS+L+ G Y FRV AVN G G+P + +EPV + Sbjct: 20906 EEWTTVSTKGEVRTTEYV-VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 20964 Query: 915 EISAGVDEQGNIY--LGFDCQEM-----TDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 EI V + ++ G D Q + TW K + + D R+ IE S L Sbjct: 20965 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 21024 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSN-EIKN------------P 1014 + + D G Y +++ + G S + + L+ A ++K+ P Sbjct: 21025 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPP 21084 Query: 1015 TIPLKSELAYEIFDK--GRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 I S + + +K R W H S++ I D R+ + GI Sbjct: 21085 LIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI--DLSEKTPFFFRVLAENEIGI 21142 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 E ++ I D K + +I K + + + ++G Sbjct: 21143 GEPCETTEPVK-AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGE 21201 Query: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKW 1163 + H +++ CE+ +V+ K+++V ++ Sbjct: 21202 QTWSHAGISKTCEI----EVSQLKEQSVLEF 21228 Score = 169 bits (429), Expect = 1e-41 Identities = 160/636 (25%), Positives = 264/636 (41%), Gaps = 66/636 (10%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P + +P W +D + LKES++ + E + +LS + K+ G YT+ Sbjct: 21278 LELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV------ 21331 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 + D++ + G P P ++ + D VI++W P + Y ++ Sbjct: 21332 -ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21390 Query: 421 RCEVGTNNW-VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD 479 + E NW + C+ K P L + Y FRVRA N G+S+P S VA Sbjct: 21391 KRETSQTNWKMVCSSVARTTFKVP--NLVKDAEYQFRVRAENRYGVSQPLVSSIIVA--- 21445 Query: 480 PLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK 539 + ++PGPP ++ + + L+W+ P G Sbjct: 21446 -------------------------KHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGG 21480 Query: 540 DPLMYF-IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSE 598 + F +EK S WQ+VN + + Y L+EG Y FRV + N GLS PS+ Sbjct: 21481 SEVTGFHVEKKERNSILWQKVNT-SPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSD 21539 Query: 599 ITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLW 656 + A P P + +R T + ++W+ P + ++GY ++ G W Sbjct: 21540 PSKFTLAVSPVDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIE-KRQGNERW 21595 Query: 657 EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPY 715 CN + ++ V GL+ G++Y FR+ A NAVG +S SQ S +I + P + Sbjct: 21596 VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEF 21655 Query: 716 GITLLNCDGHSMTLG--WKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILT 771 G DG + G ++ G P+ + ++ D E+ + E+ T L Sbjct: 21656 GPEYF--DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS-TSLF 21712 Query: 772 VDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 V T + + A N +G S + + PG + F + + Sbjct: 21713 VRDATRDHRGVYTVEAKNASG-------SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W AP+ G +P++ Y ++ RE W + A Y + L G Y FRV AV Sbjct: 21766 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSAV 21824 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNI 926 N GVG+P D S+PV+ + + T + G+ E NI Sbjct: 21825 NKFGVGRPLD-SDPVVAQIQ-YTVPDAPGIPEPSNI 21858 Score = 169 bits (427), Expect = 2e-41 Identities = 159/618 (25%), Positives = 253/618 (40%), Gaps = 50/618 (8%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK 441 AP P L D + V + W P S + GY ++ G++ W VK + Sbjct: 14659 APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITT--VKGLE 14716 Query: 442 YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V L EG Y F+V AVNSAG S P R S V + L L + + IA Sbjct: 14717 CVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAG 14775 Query: 502 DDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNA 561 D+++ + V G P ++W+ +G L QRVN Sbjct: 14776 DNIKVEIPVLGRPKPT-----------VTWK----KGDQILK-----------QTQRVNF 14809 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +T S + + + S + + + N G E ++ + IQ D+ P+ P + Sbjct: 14810 ETTATSTILNINECVRSDSGPYPLTARNIVG--EVGDVIT-IQVHDIPGPPTGP--IKFD 14864 Query: 622 RNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 + V WD P+++ + Y V+ + W I + LTTG + Sbjct: 14865 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLE 14923 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y FRVKA N G+ + ++ VP P + SMT+ W P GG Sbjct: 14924 YQFRVKAQNRYGVGPGITSACIV-ANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGG 14982 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPILGY+++++E + W V+ + I GLT+G YEF++ A N+AG +PS P Sbjct: 14983 SPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKP 15042 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 SE P PG L + ++ + W P Y+G ++ Y V+ R+ G W Sbjct: 15043 SEPMLALDPIDP-PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW 15098 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPVLVEARPGTKEISA 918 + N + VS L + Y FRV A NA G + PS+ S+ + +I Sbjct: 15099 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 15158 Query: 919 GVDEQGNIYL--GFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 V + + L G + D S W K +E+ + +I+ + L K+ Sbjct: 15159 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKD 15218 Query: 972 PDKEDLGTYSVSVSDTDG 989 + D G Y+++ ++ G Sbjct: 15219 STRRDSGAYTLTATNPGG 15236 Score = 168 bits (426), Expect = 3e-41 Identities = 145/581 (24%), Positives = 244/581 (41%), Gaps = 63/581 (10%) Query: 335 EGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDA 394 +G++ L + D GLY +++ + G++ + V D PG P++ D Sbjct: 8456 KGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDI 8508 Query: 395 NRDYVIVTWKPPNTTTESPVMGYFVDRCE--VGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 + V+ W+PP S ++ Y +++ + + W+ + ++ CKY VT L EG+ Sbjct: 8509 RKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCKYSVTKLIEGKE 8567 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y+FRVRA N G P VS + A DP G P Sbjct: 8568 YLFRVRAENRFGPGPPC-VSKPLVAKDPF------------------------GPPDAPD 8602 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +++ N +++ W P G L Y++EK V S W RVN ++ + + + V Sbjct: 8603 KPI---VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVN-KSLLNALKANV 8658 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 L+EG +YVFRV + N G + S + P A D + P P + + T++ ++W Sbjct: 8659 DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIELEW 8717 Query: 633 DRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + P +++GY+VD + GTN W C K I ++ V + G Y RV AVNA Sbjct: 8718 EPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAA 8777 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITL-LNCDGHSMTLGWK---VPKFSGGSPILGYY 746 G + V + P P + L ++ G + K +P G P+ Sbjct: 8778 GEGPPGETQPV-----TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8832 Query: 747 LDKREVH-HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 K E K+ +++ +K ++ D L + + I A N G S+ Sbjct: 8833 WTKEEGELDKDRVVIDNVGTKSELIIKDALRKDH-GRYVITATNSCG-------SKFAAA 8884 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 PGP DL ++ W P G S ++G+ ++ ++ W +T Sbjct: 8885 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET 8944 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 + ++ L +G+ Y FRV A N G G P + P+L Sbjct: 8945 ERSK--CDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PIL 8982 Score = 167 bits (424), Expect = 5e-41 Identities = 156/610 (25%), Positives = 250/610 (40%), Gaps = 58/610 (9%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P L R +P W + D +LK+++ L+ + + D G Y L +R V Sbjct: 14783 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL--TARNIVG 14840 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + ++ D + G P P+ + + D+V +W PP P+ Y V+ + Sbjct: 14841 EVGDVITIQVHD--IPGPPTGPIKFD--EVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14896 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + WV+ ++ Y T L G Y FRV+A N G+ P S + A P Sbjct: 14897 DSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPF--- 14951 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 +VPGPP + ++++ + +SW P G P++ Sbjct: 14952 ------------------------KVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILG 14987 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ WQ V ++ V + L +G +Y FRV++ N G S+PS+ + P+ Sbjct: 14988 YHVERKERNGILWQTV-SKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 15046 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNH 661 A D PG+ + T+ +V ++W +P++ + Y V+ W N Sbjct: 15047 LALDPI---DPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 15103 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPYGI--- 717 I N F V GLT Y FRV A NA G +S S+ SD I + + P + Sbjct: 15104 SNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFK 15163 Query: 718 -TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLT 776 T++ G + L V P + + D +E+ E+ + ++ D T Sbjct: 15164 DTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS-T 15220 Query: 777 EGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 + + A N G + F + P P P L EV V+ W P Sbjct: 15221 RRDSGAYTLTATNPGGFAK-----HIFNVKVLDRPGP-PEGPLAVTEVTSEKCVLSWFPP 15274 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 + G + + Y V RE W V + LKV+ L +G Y+FRV AVN GVG Sbjct: 15275 LDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTK-LKVTKLLKGNEYIFRVMAVNKYGVG 15333 Query: 897 KPSDTSEPVL 906 +P + SEPVL Sbjct: 15334 EPLE-SEPVL 15342 Score = 167 bits (424), Expect = 5e-41 Identities = 158/611 (25%), Positives = 256/611 (41%), Gaps = 64/611 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R +P W +D + LK++ + +LS HKDD G Y + + + G S Sbjct: 16951 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 17010 Query: 369 FLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTN 427 + D DP P P+ D + + + ++W PP T + Y V + + T Sbjct: 17011 EIVTLDKPDP-----PKGPVKFD--DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 17063 Query: 428 NWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQ 487 W A V VT L G Y FR+ A N G Q Sbjct: 17064 VW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYG----------------------Q 17100 Query: 488 AVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFI 546 + LE + +A Y + PGPP A+ IS++ +V+ W P G P++ Y + Sbjct: 17101 SFALESDPIVAQYP------YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 17154 Query: 547 EKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ 606 E+ S W +VN +T + ++ +L EG Y FRV + N G+ + S+ + A+ Sbjct: 17155 ERKERNSILWTKVN-KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 17213 Query: 607 DVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPI 664 D P P ++ RN + +QW +P ++ + GY V+ W + + Sbjct: 17214 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 17270 Query: 665 GYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVP----SHPYGITL 719 +F V GLT ++Y FRV A NA G +S+ S + I + + +P + T+ Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17330 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL-TEG 778 + G + L + P + + +E+ E+ ++ K ++ D + +G Sbjct: 17331 VVNAGETFRL--EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17388 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLVMLWKAPV 837 Y + A N+AG S+ F + PGP + V + W P+ Sbjct: 17389 GQYILR--ASNVAG-------SKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPL 17439 Query: 838 YSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G S +S Y V+ RE W V N LKV+ L +G YVFR+ AVN GVG+ Sbjct: 17440 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIMAVNKYGVGE 17498 Query: 898 PSDTSEPVLVE 908 P + S PVL++ Sbjct: 17499 PLE-SAPVLMK 17508 Score = 167 bits (423), Expect = 7e-41 Identities = 161/636 (25%), Positives = 268/636 (42%), Gaps = 74/636 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P+ L + R V + W P T + Y V++ ++ W++ N + + ++ Sbjct: 15055 PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15111 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V+GL E +Y FRV A N+AG IS PS SDA+ D ++ +++ V ++ + + + Sbjct: 15112 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIK-VDVKFKDTVILKA 15170 Query: 502 DD---LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + LE D PPT + W + I+ + S Sbjct: 15171 GEAFRLEADVSGRPPPT-------------MEWSKDGKELEGTAKLEIK---IADFSTNL 15214 Query: 559 VNAQTAVR-SPRYAVFDLMEG--KSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 VN + R S Y + G ++F V +R G E Sbjct: 15215 VNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-------------------- 15254 Query: 616 GRVLASRNTKTSVVVQWDRPKHEEDL-LGYYV-----DCCVAGTNLWEPCNHKPIGYNRF 669 G + + T V+ W P + + +Y+ +A TN+ + + Sbjct: 15255 GPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV-----ASEVQVTKL 15309 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V L G +YIFRV AVN G+ E + V+ V P P + SM + Sbjct: 15310 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNP-YGPPDPPKNPEVTTITKDSMVV 15368 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W P GGS I+ Y +++R+ + W + N V GLTEG YEF+I A N Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15428 Query: 790 LAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848 AGI PS S +K C+ T+ +PGP + + +S+ + W P+Y G S ++GY Sbjct: 15429 AAGISAPSPTSPFYKACD--TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYM 15486 Query: 849 VDFR--EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 V+ EED + +T A Y ++ L + + Y R+ A+N+ G+G+P+ Sbjct: 15487 VEIALPEEDEWQIVTPPAGLKATSY-TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15545 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQ-------EMTDASQFTWCKSYEEISDDERFKIE 959 E R EI D + + + C + A + W + + E D + IE Sbjct: 15546 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15603 Query: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ L + N ++ D G Y ++V ++ G S+FV Sbjct: 15604 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFV 15639 Score = 167 bits (422), Expect = 9e-41 Identities = 157/616 (25%), Positives = 246/616 (39%), Gaps = 58/616 (9%) Query: 309 RVQPRAEWYR---DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSD 365 R P+ W + D+V+ K ++ + A L + +DD G Y+L +V+ G + Sbjct: 12328 RPAPKVTWRKVGIDNVVRKG----QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG--E 12381 Query: 366 HSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVG 425 + F+ VR D PG DL+ D + V+W PP S V Y V++ E Sbjct: 12382 KAVFVNVRVLD-----TPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 12436 Query: 426 TNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 W VK + VT L G Y FRV AVN G P+ V V A DPL Sbjct: 12437 RKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL---- 12491 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 P PP + +E+++N L+W PP G + + Sbjct: 12492 -----------------------SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12528 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQA 605 I R + V+ V L EGK Y FRV + N G+S P E +A Sbjct: 12529 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12588 Query: 606 QDVTVVPS--APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKP 663 ++ + P P ++ K + H D V ++L HK Sbjct: 12589 KEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL---AVHKA 12645 Query: 664 IGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCD 723 + ++ +T + + + A N+ G ++Q+ V+ V A P P+ I+ + D Sbjct: 12646 DSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVV-VMDAPGPPQPPFDIS--DID 12700 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + +L W +P GGS I Y ++K +V +W +S +K T V L G Y F Sbjct: 12701 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIF 12759 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSP 843 ++ A N GI EP + + P + +V + + W P G SP Sbjct: 12760 RVRAENRFGISEPLTSPK--MVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSP 12817 Query: 844 VSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE 903 + GY ++ +E ++ W+ N T + + L +G Y FR+ A+N G PS +E Sbjct: 12818 IIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTE 12877 Query: 904 PVLVEA---RPGTKEI 916 V PG E+ Sbjct: 12878 YVTARMPVDPPGKPEV 12893 Score = 166 bits (420), Expect = 2e-40 Identities = 155/611 (25%), Positives = 243/611 (39%), Gaps = 63/611 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + D L + ++ + SLS + D G Y L+ + G + + Sbjct: 16268 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + A + + WKPP S ++ Y V+R E W Sbjct: 16328 VLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDIINYIVERRETSRLVWTV 16381 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 DA V+ VT L EG Y FR+ AVN G+ P S+ V A +P Sbjct: 16382 V-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEPVVAKNPF---------- 16429 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWE-PPTPRGKDPLMYFIEKSV 550 VP P + ++++ +++ WE P + G + L Y +EK Sbjct: 16430 -----------------VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRD 16472 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 W R + + + R V L+E Y FRV + N GLSEPS ++ +A D Sbjct: 16473 KEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16531 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P P T++SV + W +P ++ ++ GY V+ C W C P G N+ Sbjct: 16532 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCT-PPTGINK 16590 Query: 669 --FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHS 726 V L +Y FR+ A+N G+ E++ I V+ L P + L Sbjct: 16591 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKI---- 16646 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 + +GGS L + R W +V+ I+ V S + Sbjct: 16647 ------INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV----TSSFTSLVLD 16696 Query: 787 AVNLAGIG------EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 VN G E S ++ + P P +L E+ S+ + W+ P+ G Sbjct: 16697 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDG 16756 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 S + Y V+ RE + V N + K+ LQ+G +Y FRV A N G+G P+ Sbjct: 16757 GSKIKNYIVEKREATRKSYAAVVTNCHKNSW-KIDQLQEGCSYYFRVTAENEYGIGLPAQ 16815 Query: 901 TSEPVLVEARP 911 T++P+ V P Sbjct: 16816 TADPIKVAEVP 16826 Score = 165 bits (418), Expect = 3e-40 Identities = 154/563 (27%), Positives = 231/563 (41%), Gaps = 60/563 (10%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ AP P + D + + W PP S V GY V+ E G W + D Sbjct: 10112 DPI---APPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 10168 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 V+ K VTGL EG Y FRVRAVN AGI P V+D + D L Sbjct: 10169 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-------------- 10214 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 DL+ DA V VHA + R +S +PP + + + + + Sbjct: 10215 ----VSPDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPT-----VTWNMNERTLP--- 10261 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 Q +T S + + V+ +L+ N G + + I DV VP Sbjct: 10262 -QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIV------DVLDVPGPV 10314 Query: 616 GRVLASRN-TKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672 G + N T S + W P+ + + Y ++ + W P + N V Sbjct: 10315 GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQ 10373 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWK 732 GL G+ Y FR+ A N++GM + S+ + ++ +TVP P + + +++TL W Sbjct: 10374 GLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN 10433 Query: 733 VPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792 PK+ GGS I+ Y L+ R + + +H+V + TV GL EG YE++++AVN+ G Sbjct: 10434 PPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10493 Query: 793 IGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPV----YSGS-SPVSGY 847 G+PS ++ C+ P P L F RD + + +A YSG P + Sbjct: 10494 QGKPSFCTKPITCKDELAP---PTLHLDF---RDKLTIRVGEAFALTGRYSGKPKPKVSW 10547 Query: 848 FVDFRE--EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 F D + ED I T A +K GK V V N G + Sbjct: 10548 FKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV-----VVENSTGSRKGFCQVN 10602 Query: 906 LVEARPGTKEISAGVDEQGNIYL 928 +V+ RPG DE Y+ Sbjct: 10603 VVD-RPGPPVGPVSFDEVTKDYM 10624 Score = 162 bits (410), Expect = 2e-39 Identities = 182/806 (22%), Positives = 327/806 (40%), Gaps = 96/806 (11%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP I ++ T + +L + G P P ++WY+ G + Q+ KY++ S+ H Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR---KYKMSSDGRTH 24283 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 TL + + +D Y+ +ATN G+V T++ ++++ P Sbjct: 24284 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA----------------------TP 24321 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H EK+ + G T+ L + P P W+ LL+ S+ + Sbjct: 24322 QFHPGYPLKEKY---YGAVGSTLRLHVMYIGRP-----VPAMTWFHGQKLLQNSENITIE 24373 Query: 333 FGEGQASLSFSHLH-KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 E L ++ K G Y +++ + G D + ++D TG P+ ++ Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG----PIVIEA 24429 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 N +++WKPP S + Y V++CE Q + + + + L E Sbjct: 24430 LLKNS--AVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24487 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 Y FRV A N+ GIS P VS V P + P Sbjct: 24488 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------P 24520 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 G P + ++++ V++W+PP G + Y++EK W V + +R + Sbjct: 24521 GAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE-IRETVF 24579 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-DVTVVPSAPGRVLASRNTK--TS 627 +V +L+EG Y FRV N G SE SEI+ PI + DV + L + N + ++ Sbjct: 24580 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24639 Query: 628 VVVQWDRPKHEEDLLGYYVDCC-VAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 + H + ++ +Y + L GY++ ++ +T + +++V+A Sbjct: 24640 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRA 24699 Query: 687 VNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC-DGHSMTLGWKVPKFSGGSPILGY 745 N G S + S ++V A + +P G+ ++ G +++ K+P P++ + Sbjct: 24700 TNQGG-SVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITW 24756 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + + + ++V + S +++ +G+ + + A N GI + + Sbjct: 24757 QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT-------V 24809 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 E P P + +V S+ + W P G S ++ Y V+ A W+ V Q Sbjct: 24810 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ- 24868 Query: 866 TTANRYLKVSDLQQGKT-YVFRVRAVNANGVGKPSDTSEPVLV-EARPGTKEISAGVDEQ 923 RY ++ GKT Y FRV A N G+ KPS+ SEP + E + VDE Sbjct: 24869 ARETRYTVINLF--GKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDET 24926 Query: 924 GNIYLGFDCQEMTDASQFTWCKSYEE 949 + MT AS + + YE+ Sbjct: 24927 REV-------SMTKASHSSTKELYEK 24945 Score = 161 bits (408), Expect = 4e-39 Identities = 155/638 (24%), Positives = 255/638 (39%), Gaps = 72/638 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P +L D + +V + W+ P+ SP + Y V+R G+++W + + +K Y Sbjct: 11796 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHY 11855 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD----PLDLRRLQAVHLEGEKEIA 498 V E + Y FRV+ N G S + + V D LDL+ + ++ I Sbjct: 11856 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIR 11915 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + +A V G P + ++W +K R Sbjct: 11916 L-------EAGVRGKP-----------FPEVAWTK-------------DKDATDLTRSPR 11944 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V T S ++++ + V + N G A V PG V Sbjct: 11945 VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG---------SFVAYATVNVLDKPGPV 11995 Query: 619 LASRNTKTSVV------VQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 RN K V V WD P+ + ++ Y ++ C +W + + V Sbjct: 11996 ---RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTV 12052 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 L G +YIFRV+A N +G ++ VI + P P + MT+ Sbjct: 12053 TR-LIEGNEYIFRVRAENKIGTGPPTESKPVI-AKTKYDKPGRPDPPEVTKVSKEEMTVV 12110 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W P++ GG I GY+L+K+E H W VN S + V L Y+F++ A N Sbjct: 12111 WNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENE 12170 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 GIGEPS PS + P PGP + + S+ + W PVY G +P+ GY V+ Sbjct: 12171 IGIGEPSLPSRPVVAKDPIEP-PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVE 12229 Query: 851 FREEDAGE-----WITVNQTT-TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 R + A W N + V+ L + + Y FRV A N G+G+P++ E Sbjct: 12230 MRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEA 12289 Query: 905 VLVE--ARPGTKEISAGVDEQGNIYLG-----FDCQEMTDASQFTWCKSYEEISDDERFK 957 + + P ++ A + + + G F A + TW K + + + + Sbjct: 12290 IKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQ 12348 Query: 958 IETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 ++ V + L + N ++D G YS+++ + G + FV Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12386 Score = 161 bits (407), Expect = 5e-39 Identities = 157/614 (25%), Positives = 257/614 (41%), Gaps = 62/614 (10%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R P W++D+V LK++ E + L+ ++D G Y +++ + G + Sbjct: 15865 PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + V D G P P+ + + D + ++W PP S + Y V++ + Sbjct: 15925 IETLNVIVLDKP----GPPTGPVKMD--EVTADSITLSWGPPKYDGGSSINNYIVEKRDT 15978 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 T W Q A V L G Y FR+ A N G Sbjct: 15979 STTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAENRYG-------------------- 16017 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLM 543 ++ +L E +A Y +VPGPP + SR+ + + W EP + G + Sbjct: 16018 --KSTYLNSEPTVAQYP------FKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16069 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ S W ++N +T + ++ L EG Y FRV + N G+ +PS+++ Sbjct: 16070 YHLERKERNSILWVKLN-KTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY 16128 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D P P ++ +RN SV +QW +P ++ + GY V+ W + Sbjct: 16129 VARDPCDPPGRPEAIIVTRN---SVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 16185 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGM-SENSQESDVIKVQAALTVP----SHPYG 716 I F V GL +Y FRV A NA G+ SE S+ + I + + P Y Sbjct: 16186 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYK 16245 Query: 717 ITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774 T++ G S +KV G PI + + +E+ + E+ S+ ++ D Sbjct: 16246 DTIVVHAGES----FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDA 16301 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 + S + + A N+AG + S + P P P + V + WK Sbjct: 16302 VRVDS-GNYILKAKNVAG-----ERSVTVNVKVLDRPGP-PEGPVVISGVTAEKCTLAWK 16354 Query: 835 APVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG 894 P+ G S + Y V+ RE W TV KV+ L +G Y FR+ AVN G Sbjct: 16355 PPLQDGGSDIINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 16413 Query: 895 VGKPSDTSEPVLVE 908 VG+P + SEPV+ + Sbjct: 16414 VGEPLE-SEPVVAK 16426 Score = 160 bits (406), Expect = 6e-39 Identities = 164/646 (25%), Positives = 251/646 (38%), Gaps = 84/646 (13%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 EGE +++ P P W++D +K S M A L + D Sbjct: 8095 EGEKLSIPVPFRAVP-----VPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G+YT+ + ++ G + S + V G PG D++ D + +TW+PP Sbjct: 8150 GIYTITLENKLGSATASI-------NVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDG 8202 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 +P++ Y ++R E G ++ K+ + V L Y FRV+AVN G Sbjct: 8203 GTPILHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIE 8261 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 + + V A DP Q P PP V + + ++ Sbjct: 8262 LKNPVIAQDP---------------------------KQPPDPPVDVEVHNPTAEAMTIT 8294 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W+PP G +M Y IEK G W+R N + V Y L EGK Y FRV + N Sbjct: 8295 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCN-EHLVPILTYTAKGLEEGKEYQFRVRAEN 8353 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVL------------ASRNTKTSVVVQWDR--- 634 G+SEPS T P +A D P R AS + + W + Sbjct: 8354 AAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDEN 8413 Query: 635 ---PKHEEDLLGYYVDCCVAGTNLWEP----------CNHKPIGYNRFVVHGLTTGEQYI 681 P+ + V EP ++ G ++ V + + Sbjct: 8414 VIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGL 8473 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSP 741 + +K N G+++ V L P P + S+ W+ P GGS Sbjct: 8474 YMIKVENDHGIAKAPCTVSV------LDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSE 8527 Query: 742 ILGYYLDKRE--VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 I+ Y L+K++ W V S+ + +V L EG Y F++ A N G G P Sbjct: 8528 IINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVS 8586 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCE-VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + P+ A D E V S+++ W P +G SP+ GY+++ RE ++ Sbjct: 8587 KPLVAKDPFGPPD---APDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTH 8642 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 W VN++ V L +G TYVFRV A NA G GK S S+P Sbjct: 8643 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 8688 Score = 158 bits (399), Expect = 4e-38 Identities = 128/444 (28%), Positives = 198/444 (44%), Gaps = 35/444 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 P P + +I+++ V L+WEPP G PL Y +EK V +W +V V Sbjct: 7183 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV--MDFVTDLE 7240 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V DL++GK Y+F+V + N+ G EP+ + P+ VP P V T S+ Sbjct: 7241 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 7300 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + WD PK++ + GY V+ C G++ W C +P+ + V GL G+ Y +RVKA+ Sbjct: 7301 LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPVAETKMEVTGLEEGKWYAYRVKAL 7359 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV--PKFSGGSPILGY 745 N G S+ S+ ++ I+ P + LL G ++ G K+ P G P Sbjct: 7360 NRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL--AGLTVKAGTKIELPATVTGKPEPKI 7417 Query: 746 YLDKREVHHKNWHE--VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 K ++ K + + P K T+ VD + I AVN+ G Sbjct: 7418 TWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGTYIIEAVNVCGRATA------- 7469 Query: 804 KCEAWTMPEPGP--AYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWIT 861 E + +PGP A+D+T +V + S ++ W P G S ++ Y V+ R D+ W Sbjct: 7470 VVEVNVLDKPGPPAAFDIT--DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 7527 Query: 862 VNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVD 921 ++ T + K + L K Y+FRV A N GVG+P V+A P T + D Sbjct: 7528 LSSTVKDTNF-KATKLIPNKEYIFRVAAENMYGVGEP--------VQASPITAKYQ--FD 7576 Query: 922 EQGNIYLGFDCQEMTDASQFTWCK 945 G DA TWC+ Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCE 7600 Score = 157 bits (397), Expect = 7e-38 Identities = 168/638 (26%), Positives = 259/638 (40%), Gaps = 70/638 (10%) Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V+ A+P P P + D ++ + W+ P S V+GY V+ GT W Sbjct: 17902 VKAAEP-----PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSI 17956 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 ++ K+C VTGL G+ Y FRV+A N G S P + V A D L ++ L Sbjct: 17957 VAES--KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD---LTIQPSLKL 18011 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVV 551 +DL+ + V G P +SW + +PL Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPN-----------ISWV----KDGEPLK-------- 18048 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF---RVLSANRHGLSEPSEITSPIQAQDV 608 RVN + S V + EG F V + N G + +E S I V Sbjct: 18049 ---QTTRVNVEETATS---TVLHIKEGNKDDFGKYTVTATNSAGTA--TENLSVI----V 18096 Query: 609 TVVPSAP-GRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIG 665 P P G V + VV+ W+ P + + Y V+ T W + + Sbjct: 18097 LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS-ATVA 18155 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 + L TG +Y FR+ A N G S VI VQ P P + + Sbjct: 18156 RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI-VQYPFKEPGPPGTPFVTSISKD 18214 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 M + W P GG+ I+GY+L+++E + W ++N +P + T GL EG YEFK+ Sbjct: 18215 QMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKV 18274 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 +A N+ GIG+PS SE F P P + + ++ + WK P Y G S ++ Sbjct: 18275 SAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV----ITRNNVTLKWKKPAYDGGSKIT 18330 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEP 904 GY V+ ++ G W+ + T VS L + + Y FRV A NA G +PSD+S Sbjct: 18331 GYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSG- 18389 Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEM---------TDASQFTWCKSYEEISDD-E 954 + AR +A +D + + E W K +E+ + Sbjct: 18390 -AITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAA 18448 Query: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 R +I++ + L +K+ + D G Y + +S+ G S Sbjct: 18449 RMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18486 Score = 151 bits (382), Expect = 4e-36 Identities = 175/732 (23%), Positives = 295/732 (40%), Gaps = 58/732 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP +I + V+ WEPP G ++ Y +EK + + + +R + Sbjct: 8497 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8556 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y+V L+EGK Y+FRV + NR G P ++ P+ A+D P AP + + T S++ Sbjct: 8557 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8615 Query: 630 VQWDRPK-HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 V+W+ PK + +LGY+++ + W N + + V GL G Y+FRV A N Sbjct: 8616 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8675 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 A G + S SD ++ P P + + ++ L W+ P F+GG I+GY++D Sbjct: 8676 AAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVD 8734 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 K+ V W K TV + EG+ Y+ +++AVN AG G P + E Sbjct: 8735 KQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-- 8792 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWK-----APVYSGSSPVSGYFVDFREEDAGEWITVN 863 P+ PA +L V+ +M K A V P + + E D + N Sbjct: 8793 --PQEPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN 8849 Query: 864 QTTTANRYLKVSDLQQGKTYV----------FRVRAVNANGVGKPSDTSEPVLVEARPGT 913 T + +K + + YV F V V P +PV+ + Sbjct: 8850 VGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL 8909 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPD 973 S D+ G+ GF E DA TW + E ER K + G L+ + Sbjct: 8910 LNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIE----TERSKCDITG-----LLEGQE 8959 Query: 974 KEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVR 1033 + + V + G P E+ ++A+ + + PT P L Y K + Sbjct: 8960 YK----FRVIAKNKFGCG-----PPVEIGPILAV-DPLGPPTSP--ERLTYTERTKSTIT 9007 Query: 1034 F-WLQAEHLSPDASYRFIINDREVSDSEIHRIK---CDKATGIIEMVMDRFSIENEGTYT 1089 W + +II R + R+ C + ++E + + E Sbjct: 9008 LDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAV 9067 Query: 1090 VQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLV 1149 +I + + ++V+ D ++ R + ++ + E +H + + + Sbjct: 9068 NEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA---GEPVH--IPADVTGLPM 9122 Query: 1150 CKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQD 1209 K+ +K ETV + D L T+ + EL IPK ++D G Y T + G Sbjct: 9123 PKIEWSKNETVIE-KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9181 Query: 1210 VSILEIAGKVYD 1221 + + +VYD Sbjct: 9182 FRNVHV--EVYD 9191 Score = 151 bits (382), Expect = 4e-36 Identities = 151/584 (25%), Positives = 239/584 (40%), Gaps = 82/584 (14%) Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPP 406 + D G Y + + G +A + V D PG +DL+ NR ++ W P Sbjct: 8863 RKDHGRYVITATNSCGSKFAAARVEVFDV-------PGPVLDLKPVVTNRKMCLLNWSDP 8915 Query: 407 NTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGIS 466 S + G+ ++R + + W Q + C +TGL EG+ Y FRV A N G Sbjct: 8916 EDDGGSEITGFIIERKDAKMHTWRQPIETERSKC--DITGLLEGQEYKFRVIAKNKFGCG 8973 Query: 467 RPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG---VHASEIS 523 P + + A+DPL GPPT + +E + Sbjct: 8974 PPVEIG-PILAVDPL------------------------------GPPTSPERLTYTERT 9002 Query: 524 RNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYV 582 ++ + L W+ P G P+ Y IEK ++RVN + + + V +L E + Y Sbjct: 9003 KSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLC-PTTSFLVENLDEHQMYE 9061 Query: 583 FRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH-EEDL 641 FRV + N G SEPS + + QD V P+ R+ +T + V+ P H D+ Sbjct: 9062 FRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDT---IKVKAGEPVHIPADV 9117 Query: 642 LGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------------QYIFRVKAV 687 G + N E KP + ++ E + + V A Sbjct: 9118 TGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 9175 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYL 747 N +G + +V PS P + + + S L W P +GGS I Y + Sbjct: 9176 NRLGSVFRNVHVEV------YDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9229 Query: 748 DKREVHHK--NWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 DKR+ K W EV ++ + + L YEF++ AVN GI + + Sbjct: 9230 DKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9288 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 + + +P P P + + LV W P+ +G SP++GY+++ REE + W V++ Sbjct: 9289 DPYRLPGP-PGKPKVLARTKGSMLVS-WTPPLDNGGSPITGYWLEKREEGSPYWSRVSRA 9346 Query: 866 TTANRYLK-----VSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 LK V L +G Y FR A+NA G+G PS+ S+P Sbjct: 9347 PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9390 Score = 150 bits (379), Expect = 9e-36 Identities = 109/444 (24%), Positives = 202/444 (45%), Gaps = 39/444 (8%) Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 T + + + +G ++++ N+HG +E I + + V PG V Sbjct: 6742 TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF-----INLKVIDV----PGPVRNLE 6792 Query: 623 NTKT---SVVVQWDRPKHE--EDLLGYYVD-------CCVAGTNLWEPCNHKPIGYNRFV 670 T+T V + W+ P + ++GY V+ V T+ E C F Sbjct: 6793 VTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE--------FT 6844 Query: 671 VHGLTTGE-QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V GL G +Y+FRV A N VG E + + ++ ++ VP P +T+ + + ++L Sbjct: 6845 VTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSL 6904 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W+ P++ GG+ I Y ++ R+ W + ++ TV + EG Y F++ A N Sbjct: 6905 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQN 6964 Query: 790 LAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849 G+G+PS + K A + P P +LT + +S+ + W+ P+ G SP+ GY + Sbjct: 6965 RIGVGKPSAATPFVKV-ADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 7023 Query: 850 DFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA 909 + EE WI N KV+ L++G Y++RV A N GV PS+ P+ + Sbjct: 7024 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 7083 Query: 910 R--PGTKEISAGVDEQGNIYLGFDCQEMTDASQF-----TWCKSYEEISDDERFKIETVG 962 T ++SA D + + + ++ + TWC + + +R K++T+ Sbjct: 7084 AFVEPTMDLSAFKDGL-EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7142 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSD 986 +++L + ++ D G Y++ + + Sbjct: 7143 AYAELVISPSERSDKGIYTLKLEN 7166 Score = 150 bits (378), Expect = 1e-35 Identities = 138/520 (26%), Positives = 208/520 (40%), Gaps = 88/520 (16%) Query: 375 ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD--RCEVGTNNWVQC 432 +DPL P P L+ + ++ + W PP + + GY E + W + Sbjct: 12488 SDPL--SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEY 12545 Query: 433 NDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAA----LDPLDLRRLQ- 487 + VK VTGL EG+ Y FRV A N+ G+S P A L P L Q Sbjct: 12546 S--VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI 12603 Query: 488 -------------------------------------AVHLEGEKEIAIYQDDLEGDA-- 508 AVH I I +D D+ Sbjct: 12604 TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12663 Query: 509 ---------------------QVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YF 545 PGPP S+I + LSW P G + Y Sbjct: 12664 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYI 12723 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP-IQ 604 +EK V G W V A +V V L+ G+ Y+FRV + NR G+SEP +TSP + Sbjct: 12724 VEKCDVSRGDW--VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMV 12779 Query: 605 AQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHK 662 AQ VPS P ++ K + V WDRP + ++GY ++ + LW N Sbjct: 12780 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12839 Query: 663 PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC 722 + + GL G +Y FR+ A+N G S S+ ++ + + + P P +++ Sbjct: 12840 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKP---EVIDV 12896 Query: 723 DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTVDGLTEGSL 780 +++L W PK GGS I+GY+++ ++ W N++P + T GL E + Sbjct: 12897 TKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQ 12956 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLT 820 Y+F+ A I PS+PS+ A +P P DL+ Sbjct: 12957 YQFRAIARTAVNISPPSEPSDPVTILAENVP---PRIDLS 12993 Score = 149 bits (376), Expect = 2e-35 Identities = 199/866 (22%), Positives = 327/866 (37%), Gaps = 118/866 (13%) Query: 150 ISRAPEIL--VRLRSHTVWER-MSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 I APEI V LR+ + + V++ +G P P V W KD + A +Y IE Sbjct: 20960 ILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA---RYSIE 21016 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 + L I + +DT Y N +G P Sbjct: 21017 NTDSSSLLTIPQVTRNDTGKYILTIENG----------------------------VGEP 21048 Query: 267 LSSMIPYTHFDVQFL-EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKE 325 SS + D +K V G TVTL + P + P + + + Sbjct: 21049 KSSTVSVKVLDTPAACQKLQVKHVSRG-TVTL---LWDPPLIDGGSPIINYVIEKRDATK 21104 Query: 326 SKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGA 385 W+ + +S SF + ++ + R+++ + +P+ A Sbjct: 21105 RTWSVV--SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEP---CETTEPVKAAEVPA 21159 Query: 386 PM-DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPV 444 P+ DL D+ + VI++W P+ S + Y V+R G W + K C+ V Sbjct: 21160 PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGIS--KTCEIEV 21217 Query: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504 + L E FRV A N G+S P + P+ ++ L I + DL Sbjct: 21218 SQLKEQSVLEFRVFAKNEKGLSDP-------VTIGPITVKEL----------IITPEVDL 21260 Query: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTA 564 + +PG V I N + E P P + +++ + Sbjct: 21261 ---SDIPGAQVTVR---IGHN---VHLELPYKGKPKPSISWLKDGL-------------P 21298 Query: 565 VRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ--AQDVTVV----PSAP-GR 617 ++ + F E K + + HG + + + A +TV+ PS P G Sbjct: 21299 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21358 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHK----PIGYNRFVVHG 673 + SV++ WD P ED G + C N K + F V Sbjct: 21359 IRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPN 21415 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 L +Y FRV+A N G+S+ S +I + +P P + N M+L W Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQ-PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDA 21474 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 P + GGS + G++++K+E + W +VN+SP GL EG Y+F++ A N AG+ Sbjct: 21475 PVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21534 Query: 794 GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE 853 PSDPS+ + P P Y +V ++ + W P+ G S + GY ++ R+ Sbjct: 21535 SSPSDPSKFTLAVSPVDPPGTPDY----IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ 21590 Query: 854 EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP----------SDTSE 903 + W+ N T + V+ L G Y FR+ A NA G P D + Sbjct: 21591 GNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV 21649 Query: 904 PVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGD 963 P +VE G + + + G + + TW K EI +I V Sbjct: 21650 PPIVEF--GPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG 21707 Query: 964 HSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L++++ ++ G Y+V + G Sbjct: 21708 STSLFVRDATRDHRGVYTVEAKNASG 21733 Score = 149 bits (376), Expect = 2e-35 Identities = 139/518 (26%), Positives = 220/518 (42%), Gaps = 56/518 (10%) Query: 511 PGPPTG-VHASEISRNYVVLSWEPPTPRG-KDPLMYFIEKSVVGSGSWQRVNAQTAVRSP 568 P P G + +I V +SW PP G D L Y +E+ V +W ++++ VR Sbjct: 23923 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR--VRGT 23980 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ---DVTVVPSAPGRVLASRNTK 625 V L E Y FRV + N+ G+S+P + P+ + + PS P VL TK Sbjct: 23981 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV--TK 24038 Query: 626 TSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFR 683 +SV + W RPK + + GYY++ T+ W N I + V GL +Y FR Sbjct: 24039 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24098 Query: 684 VKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPIL 743 + A N VG+SE S S+ + + PS P + +L+ S+TL W+ P+ GG IL Sbjct: 24099 IIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEIL 24158 Query: 744 GYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 GY+++ R+ W + N K T+ GL E + YEF++ A N G+ P + Sbjct: 24159 GYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSI 24218 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 K + + PG E++D + + G + + R +W Sbjct: 24219 KTKLTSGEAPGIRK-----EMKDVTTKL--------GEAAQLSCQIVGRPLPDIKWYRFG 24265 Query: 864 QTTTANRYLKVSDLQQGKTYVFRV-----------RAVNANGVGKPSDTSEPVLVEARP- 911 + +R K+S G+T+ V + N VG+ +TS +L++A P Sbjct: 24266 KELIQSRKYKMS--SDGRTHTLTVMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQ 24322 Query: 912 -----GTKEISAGVD----EQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVG 962 KE G +Y+G M TW + + + E IE Sbjct: 24323 FHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAM------TWFHGQKLLQNSENITIENTE 24376 Query: 963 DHSKLYLKNPD-KEDLGTYSVSVSDTDGVSSSFVLDPE 999 ++ L +KN K G Y V +S+ G + +LD E Sbjct: 24377 HYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA-ILDVE 24413 Score = 147 bits (371), Expect = 7e-35 Identities = 164/689 (23%), Positives = 272/689 (39%), Gaps = 81/689 (11%) Query: 250 RGDEEPFRSVGLP-----IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 +G +P R +G+P I + S +P+ F+V+ E+ + +G Sbjct: 19069 KGRSDP-RQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKG------------ 19115 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 R Q W +D LKE+ + + SLS K+D G Y L + + G Sbjct: 19116 ----RPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 19171 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + V D PG P ++ + + D + ++W PP + Y V++ E Sbjct: 19172 TVPITIIVLDR-------PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKET 19224 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + W + A V + L G Y FRV A N G S S S VA Sbjct: 19225 TSTTWHIVSQA-VARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA-------- 19275 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 E PGPP +++ ++++W+ P G ++ Sbjct: 19276 --------------------EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIG 19315 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E S W + N + + + V L EG Y +RV + N G+ + S+ P+ Sbjct: 19316 YHLEYKERSSILWSKAN-KILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19374 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D PG+ + T+ SV ++W +P ++ + GY V+ W CN+ Sbjct: 19375 PARDPC---DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19431 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAV-GMSENSQESDVIKVQAALTVPSHPYGITLL 720 I F V LT ++Y FRV A NA +SE S+ + I V+ + P + Sbjct: 19432 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFR 19491 Query: 721 NCDGHSMTLGWKVPKFSGGS--PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 + K+ G P++ + D E+ + E+ S+ + T+LTV Sbjct: 19492 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNH-TLLTVKDCIRR 19550 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 ++ + N+AG S C+ P P PA L + + W P Sbjct: 19551 DTGQYVLTLKNVAG-----TRSVAVNCKVLDKPGP-PAGPLEINGLTAEKCSLSWGRPQE 19604 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G + + Y V+ RE W T+ + KV+ L +G Y+FRV VN GVG+P Sbjct: 19605 DGGADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19663 Query: 899 SDT-----SEPVLVEARPGTKEISAGVDE 922 ++ +P V + P + EI++ E Sbjct: 19664 LESVAIKALDPFTVPSPPTSLEITSVTKE 19692 Score = 144 bits (364), Expect = 5e-34 Identities = 163/681 (23%), Positives = 264/681 (38%), Gaps = 79/681 (11%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P+ RD V LK + +++ D G Y + + G + + Sbjct: 20201 PKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV 20260 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + D + V + W+PP S V Y + + E T W + Sbjct: 20261 VLDRP----GPPTGPVVIS--DITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20314 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 + A V V L G Y FR++A N GIS D +D + Sbjct: 20315 VS-ATVARTMMKVMKLTTGEEYQFRIKAENRFGIS------------DHIDSACVT---- 20357 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550 ++ PGPP+ + ++R + + W P G ++ Y +E Sbjct: 20358 ------------VKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD 20405 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 S WQ+ N + +R+ + V + G Y FRV + N G+ +PS + P+ A D Sbjct: 20406 RNSILWQKAN-KLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC- 20463 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P V + +K SV + W +P + + GY V+ W + + + Sbjct: 20464 --EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20521 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY-GITLLNCDGHSM 727 F++ GLT QY FRV A NAVG N S+V+ + P + L + Sbjct: 20522 FIISGLTQNSQYEFRVFARNAVGSISNP--SEVVGPITCIDSYGGPVIDLPLEYTEVVKY 20579 Query: 728 TLGWKVPKFSGGS----PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG--LTEGSLY 781 G V +G S P + +Y D +E+ V ++ +IL D L G Y Sbjct: 20580 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-Y 20638 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 E K+ N G S + + P P P + F V + +LW+ P G Sbjct: 20639 ELKLR--NAMG-----SASATIRVQILDKPGP-PGGPIEFKTVTAEKITLLWRPPADDGG 20690 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 + ++ Y V+ RE W V++ + + + +G Y+FRVRAVN G+G+P ++ Sbjct: 20691 AKITHYIVEKRETSRVVWSMVSEHLE-ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20749 Query: 902 SEPVLVEA-----RPGTKEI------------SAGVDEQGNIYLGFDCQEMTDASQFTWC 944 V A PG E+ S + + G+ G+ E D W Sbjct: 20750 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY-FLEKRDKKSLGWF 20808 Query: 945 KSYEEISDDERFKIETVGDHS 965 K +E D R K+ + ++S Sbjct: 20809 KVLKETIRDTRQKVTGLTENS 20829 Score = 141 bits (355), Expect = 5e-33 Identities = 122/473 (25%), Positives = 210/473 (44%), Gaps = 49/473 (10%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+ ++ L WEPP G + Y I+K ++ V+++ + S Sbjct: 17811 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTS-- 17868 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V +L EG Y FRV++ N G+ P E ++A + PS PG+V + ++TS Sbjct: 17869 FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP---PSPPGKVTLTDVSQTSAS 17925 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ GT W + VV GL++G++Y FRVKA Sbjct: 17926 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC--NAVVTGLSSGQEYQFRVKAY 17983 Query: 688 NAVGMSEN-----SQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 N G S+ + + +Q +L +P + Y I G + + ++P P Sbjct: 17984 NEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQA----GEDLKI--EIPVIGRPRPN 18037 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 + + D + V + + T+L + + ++ + A N AG +E+ Sbjct: 18038 ISWVKDGEPLKQTTRVNVEETATS-TVLHIKEGNKDDFGKYTVTATNSAGTA-----TEN 18091 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P P P + F EV +V+ W+ P Y+G +S Y V+ R+ W V Sbjct: 18092 LSVIVLEKPGP-PVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMV 18150 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE------ARPGTKEI 916 + T A +K++ L+ G Y FR+ A N G P D S+ V+V+ PGT + Sbjct: 18151 S-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIVQYPFKEPGPPGTPFV 18208 Query: 917 SA------------GVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFK 957 ++ V++ G +G+ E + + W K + D +FK Sbjct: 18209 TSISKDQMLVQWHEPVNDGGTKIIGYHL-EQKEKNSILWVKLNKTPIQDTKFK 18260 Score = 140 bits (353), Expect = 9e-33 Identities = 116/421 (27%), Positives = 187/421 (44%), Gaps = 32/421 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGP + ++I+++ V L W+ P G + Y +EK S+ A T Sbjct: 14563 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS--TATTKCHKCT 14620 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y V L EG Y FRV++ N +G+ EP+E T P++A + PS P + TK++V Sbjct: 14621 YKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLNIMDITKSTVS 14677 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W +PKH+ + GY ++ G++ W + + VV LT GE+Y F+V AV Sbjct: 14678 LAWPKPKHDGGSKITGYVIEAQRKGSDQW--THITTVKGLECVVRNLTEGEEYTFQVMAV 14735 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI---TLLNCDGHSMTLGWKVPKFSGGSPILG 744 N+ G S + VI + + GI ++ G ++ + ++P P + Sbjct: 14736 NSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV--EIPVLGRPKPTVT 14793 Query: 745 YYLDKREVHHKNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 + K + K VN + + TIL ++ + + A N+ G + + Sbjct: 14794 W--KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG-----EVGDVI 14846 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 + +P P P + F EV + W P G P+S Y V+ R+ D+ W+ + Sbjct: 14847 TIQVHDIPGP-PTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14905 Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE------PVLVEARPGTKEIS 917 T Y K + L G Y FRV+A N GVG P TS P V PGT +++ Sbjct: 14906 TTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPFKVPGPPGTPQVT 14963 Query: 918 A 918 A Sbjct: 14964 A 14964 Score = 136 bits (343), Expect = 1e-31 Identities = 112/417 (26%), Positives = 180/417 (43%), Gaps = 28/417 (6%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+++ V L+W+PP G + Y +EK ++ V T Sbjct: 15647 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV--ATNCHKTS 15704 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V L EG SY FRVL+ N +G+ P+E ++A + P PG++ T+ SV Sbjct: 15705 WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASE---RPLPPGKITLMDVTRNSVS 15761 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ G++ W C + + GL GE+Y FRV A Sbjct: 15762 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQ 15819 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI-TLLNCDGHSMTLGWKVPKFSGGSPILGYY 746 N G+S+ Q S + + + P+ T G + + VP +P + ++ Sbjct: 15820 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKV--DVPFIGRPTPAVTWH 15877 Query: 747 LDKREVHHKNWHEVNS-SPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D V K VN+ S ++LT+ + + + N AG + E Sbjct: 15878 KD--NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG-----EAIETLNV 15930 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P P P + EV S+ + W P Y G S ++ Y V+ R+ W V+ Sbjct: 15931 IVLDKPGP-PTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-A 15988 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGV-----GKPSDTSEPVLVEARPGTKEIS 917 T A +K L+ G Y FR+ A N G +P+ P V PGT ++ Sbjct: 15989 TVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 16045 Score = 134 bits (337), Expect = 6e-31 Identities = 174/771 (22%), Positives = 294/771 (38%), Gaps = 127/771 (16%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT-LEINRADFDDTATYSA 229 ++L ++G P P+ +W K+G I + A + + HT L I AD D+ TY Sbjct: 23849 IRLTIPIKGKPFPICKWTKEGQDISKRA------MIATSETHTELVIKEADRGDSGTYDL 23902 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 V N G+ + V V IG P S P + D+Q + V++R Sbjct: 23903 VLENKCGKKAVYIKVRV----------------IGSPNSPEGPLEYDDIQ-VRSVRVSWR 23945 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 + + +R P+A WY D ++ + SL L ++ Sbjct: 23946 PPADDGGADILGYILE--RREVPKAAWYTIDSRVRGT------------SLVVKGLKENV 23991 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCH-----DANRDYVIVTWK 404 E + + ++ G+S ++ +P+ P P + + D + V ++W Sbjct: 23992 EYHFRVSAENQFGISKP-----LKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 24046 Query: 405 PPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG 464 P S V GY+++R E T+ WV+ N + Y VTGL Y FR+ A N G Sbjct: 24047 RPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVG 24106 Query: 465 ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISR 524 +S S S+ V DP D P P + IS+ Sbjct: 24107 LSETSPASEPVVCKDPFD---------------------------KPSQPGELEILSISK 24139 Query: 525 NYVVLSWE-PPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF 583 + V L WE P GK+ L Y++E G +W++ N + ++ ++ + L+E Y F Sbjct: 24140 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE-RIKDKQFTIGGLLEATEYEF 24198 Query: 584 RVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG--RVLASRNTKTSVVVQWD-----RPK 636 RV + N GLS P I+ + APG + + TK Q RP Sbjct: 24199 RVFAENETGLSRPRRTAMSIKTK--LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 24256 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY---IFRVKAVNAVGMS 693 D+ Y G L + +K R + T EQ ++ A N VG Sbjct: 24257 --PDIKWYRF-----GKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEV 24309 Query: 694 ENSQESDVIKVQAALTVPSHP--------YGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 E S K+ T HP YG H M +G VP + + Sbjct: 24310 ETSS-----KLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT-------W 24357 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + ++ + + + ++ ++ + + ++K+ N+ G + Sbjct: 24358 FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI-----LDV 24412 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE-EDAGEWITVNQ 864 E P+ P + + S V+ WK P G S ++ Y V+ E ++ EW V+ Sbjct: 24413 EIQDKPDK-PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSS 24471 Query: 865 TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA---RPG 912 + ++ +L + Y FRV A N G+ P + S V++++ +PG Sbjct: 24472 AISVTT-CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG 24521 Score = 121 bits (304), Expect = 4e-27 Identities = 113/424 (26%), Positives = 188/424 (44%), Gaps = 38/424 (8%) Query: 493 GEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVV 551 G+KE I L+ PGPP V EIS++ ++WEPP G P++ Y ++K Sbjct: 13468 GKKEYTIVVKVLD----TPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDA 13523 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV 611 SW V + + S + V +L EGKSY FRV + N +G+ +P E ++A Sbjct: 13524 ERKSWSTVTTECSKTS--FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS----- 13576 Query: 612 PSAPGRVL---ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGY 666 PG V+ +K+S + W +P + ++GY VD + N W+ K + Sbjct: 13577 -QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRV-MKSLSL 13633 Query: 667 NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK---VQAALTVPSHPYGITLLNCD 723 ++ LT G++Y FRV A N G S+ + V + V L + P + L + Sbjct: 13634 -QYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLP-DLCYLAKE 13691 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + L K+P +P + + + + V SS T++ D + ++ Sbjct: 13692 NSNFRL--KIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKY 13748 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG-PAYDLTFCEVRDTSLVMLWKAPVYSGSS 842 I N+AG E + + +PG P + F EV ++ + W P G S Sbjct: 13749 TITLKNVAGTKEGT-------ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGS 13801 Query: 843 PVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 ++ Y ++ R+ +W+T + +V+ L +G Y FRV A N GVG+ S Sbjct: 13802 EITNYILEKRDSVNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGE-GLKS 13859 Query: 903 EPVL 906 EP++ Sbjct: 13860 EPIV 13863 Score = 111 bits (278), Expect = 4e-24 Identities = 93/324 (28%), Positives = 134/324 (41%), Gaps = 41/324 (12%) Query: 152 RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRI-ESNYG 210 +AP LR+ V + + L V G P P+V+WY+ G I A+ KYRI E G Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKGG 24678 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 H L I DD Y ATN G VS A+ L + +P Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-----------------LEVEVPAKIH 24721 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 +P T LE G GE V++K PD P W + L+ + + Sbjct: 24722 LPKT------LEGMGAVHALRGEVVSIKIPFSGKPD-----PVITWQKGQDLIDNNGHYQ 24770 Query: 331 MFFGEGQASLSFSH-LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDL 389 + SL F + + + D G Y + +R G+ + L V D P P + Sbjct: 24771 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADV-------PDPPRGV 24823 Query: 390 QCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFE 449 + D +RD V +TW P + S + Y V++C W++ A + +Y V LF Sbjct: 24824 KVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RETRYTVINLFG 24881 Query: 450 GRSYIFRVRAVNSAGISRPSRVSD 473 SY FRV A N G+S+PS S+ Sbjct: 24882 KTSYQFRVIAENKFGLSKPSEPSE 24905 Score = 95.5 bits (236), Expect = 3e-19 Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 25/408 (6%) Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCN 660 ++ QD P+ P ++ K S V+ W P + + Y V+ C A Sbjct: 24412 VEIQDKPDKPTGP--IVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24469 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 I + LT Y FRV A N G+S+ + S V+ +++ P P T+ Sbjct: 24470 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24529 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 S + WK P GG+ I YYL+KRE W V + + T+ +V L EG Sbjct: 24530 AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLE 24589 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY--DLTFCEVRDTSLVMLWKAPVY 838 YEF++ NL G E S+ SE ++ +P P + +L VR S L V Sbjct: 24590 YEFRVKCENLGGESEWSEISEPITPKS-DVPIQAPHFKEELRNLNVRYQSNATL-VCKVT 24647 Query: 839 SGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG--- 894 P+ ++ +E A G + + L ++ + V++VRA N G Sbjct: 24648 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 24707 Query: 895 ------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYE 948 V P+ P +E G + A E +I + F + TW K + Sbjct: 24708 GTASLEVEVPAKIHLPKTLE---GMGAVHALRGEVVSIKIPFSGK---PDPVITWQKGQD 24761 Query: 949 EISDDERFKIETVGDHSKLYLKN-PDKEDLGTYSVSVSDTDGVSSSFV 995 I ++ +++ + L N +++D G Y V + G+ V Sbjct: 24762 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24809 Score = 77.8 bits (190), Expect = 7e-14 Identities = 113/534 (21%), Positives = 206/534 (38%), Gaps = 93/534 (17%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K+ EI E+FKI G +L + N ED Y+ V D Sbjct: 2855 FECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-VCGNDQ 2913 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 VS++ + P + ++ N + TI + + YE SY++ Sbjct: 2914 VSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYE------------------GISYKW 2955 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + N E+ ++ +++ K T + + F + T+ GKA S ++L + Sbjct: 2956 LKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYV---- 3007 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDV- 1168 E + EF + H + V E+ C+V+ + + +W+KDD Sbjct: 3008 --------EARHIEFRK----HIKDI---KVLEKKRAMFECEVS--EPDITVQWMKDDQE 3050 Query: 1169 LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAM 1227 L T+ + E+ + LLIP D G+Y G +VS ++ + D I ++ Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGRDVRIRSI 3106 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS--EHMRIGGSEEM 1285 + ++V+ E R + D++ +W +I+ E + + Sbjct: 3107 KK-------EVQVI---EKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRI 3156 Query: 1286 AWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGR 1345 + I E + D G+YTF G++ +L ++ + E Q Sbjct: 3157 HRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQELQP------------- 3201 Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVK-VEQAKYVSMT 1404 VT+ GK + G P P++ W+K +Q LS F K + + ++ Sbjct: 3202 --------VTVQSGKPARFCAVISGRPQPKISWYKEEQ--LLSTGFKCKFLHDGQEYTLL 3251 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPA 1458 + ED+ Y+ KN YG ++SV ++P++ P Q P PA Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSV-----EVPEVVSPDQEMPVYPPA 3300 Score = 65.9 bits (159), Expect = 3e-10 Identities = 67/248 (27%), Positives = 102/248 (41%), Gaps = 30/248 (12%) Query: 30 DEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRY 89 +EY K A ++SS S R + + L + + R E+ E + R Sbjct: 25944 EEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRS 26003 Query: 90 QSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEER 149 + E R R S ++ + L+R + + D ++ + M+ L ++ T E + Sbjct: 26004 PT-----PERTRPRSPSPVS---SERSLSRFERSARFDIFSRYESMKAALKTQK-TSERK 26054 Query: 150 ----------ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE 199 + AP I +R+RSH V + + VQ PT V+WY +G + E Sbjct: 26055 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG---VELQE 26111 Query: 200 PGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVV--------RRFRG 251 K + GV TLEI DD+ TY AV TN G+ S A + V R Sbjct: 26112 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR 26171 Query: 252 DEEPFRSV 259 DEE RSV Sbjct: 26172 DEEVPRSV 26179 Score = 65.9 bits (159), Expect = 3e-10 Identities = 50/166 (30%), Positives = 76/166 (45%), Gaps = 22/166 (13%) Query: 1262 VNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTF--EIFDGKDNHQRSLDLS 1319 V W ++++SE R G S L I + + +D+G T + +G Q L LS Sbjct: 26763 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26822 Query: 1320 GQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWF 1379 + D A AF + R + I EG+ + TC + G P PE+ WF Sbjct: 26823 KELSD----------APAFISQPRSQ---------NINEGQNVLFTCEISGEPSPEIEWF 26863 Query: 1380 KNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 KN+ I +S + S+ + Y S+ I+ + DSGKY+I KN G Sbjct: 26864 KNNLPISISSNVSISRSRNVY-SLEIRNASVSDSGKYTIKAKNFRG 26908 Score = 63.9 bits (154), Expect = 1e-09 Identities = 61/247 (24%), Positives = 97/247 (39%), Gaps = 22/247 (8%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + +L++ + E +++ G P P + W K+ +I P K RIE G Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L+I+ D+A Y+A A N G+ +T V V + EP R + +P G + I Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAA 1628 Query: 274 THFDVQFLE------KFGVTFRREGETVTLKCTMLVTPDLKRVQPR-------------- 313 + L + G + +E + L + LKR P Sbjct: 1629 PELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTM 1688 Query: 314 -AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372 EW D L+ + +M G SL + + D G+ T R ++ G SA L V Sbjct: 1689 VVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748 Query: 373 RDADPLV 379 +D LV Sbjct: 1749 KDEKSLV 1755 Score = 62.0 bits (149), Expect = 4e-09 Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 123 RDKLDKYAIQQMMEDKLAWERHTFEERI-SRAPEILVRLRSHTVWERMSVKLCFTVQGFP 181 R+ D Y + M + K R T R+ R PE + L + T + +V+ T+ P Sbjct: 25357 REVYDYYCRRTMKKIK----RRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 25412 Query: 182 TPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTN 241 P V WYK G I KY ES+ G++ L IN DD A Y+ VA N +G+ S Sbjct: 25413 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 25472 Query: 242 AAVVV 246 A + V Sbjct: 25473 AKLTV 25477 Score = 61.6 bits (148), Expect = 5e-09 Identities = 73/333 (21%), Positives = 124/333 (37%), Gaps = 48/333 (14%) Query: 76 STQEDEEQENRSRYQSLVA--AYGEAKRQRFLS-ELAHLEEDVHLARSQARDKLDKYAIQ 132 ++Q +E+ RS + L AY + ++ E + +V ++ R+ L Y Sbjct: 26167 ASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26226 Query: 133 QMMEDK-LAWERHTFEERISR-------APEILVRLRSHTVWERMSVKLCFTVQGFPTPV 184 E K A E + EE+ + A IL + RS TV+E S + G P P Sbjct: 26227 ASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT 26286 Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W + G ++ +A ++++ + T EI+ D YS V N+ G+ + Sbjct: 26287 VTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26343 Query: 245 VVRRFRGDEEPFRS----------------------VGLPIGLPLSSMIP---------- 272 +++ R E+ S V P ++ P Sbjct: 26344 TIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEK 26403 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H V K + E K T +V + R + WY+D LKE+ + Sbjct: 26404 VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK-EVTWYKDGKKLKENGHFQFH 26462 Query: 333 FG-EGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 + +G L ++L + D+G Y I GG S Sbjct: 26463 YSADGTYELKINNLTESDQGEYVCEISGEGGTS 26495 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D+VTI G L L V G P+P++IW K D+++ L E S++ K + IK Sbjct: 22750 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY-TGKRATAVIKFCDRS 22808 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ +KN G + + V V V Sbjct: 22809 DSGKYTLTVKNASGTKAVSVMVKV 22832 Score = 59.3 bits (142), Expect = 3e-08 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 24/201 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++L L+ TV + C + G P P + WYK+ L+ K + + +T Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF---KCKFLHDGQEYT 3249 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L + A +D A Y+ A N +G +T+A++ SV +P + +P Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASL-------------SVEVPEVVSPDQEMPV 3296 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + T EG+ +C + T DLK WY D +K S++ +M Sbjct: 3297 --YPPAIITPLQDTVTSEGQPARFQCRVSGT-DLK-----VSWYSKDKKIKPSRFFRMTQ 3348 Query: 334 GEGQASLSFSHLHKDDEGLYT 354 E L + + +DEG YT Sbjct: 3349 FEDTYQLEIAEAYPEDEGTYT 3369 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/337 (21%), Positives = 124/337 (36%), Gaps = 49/337 (14%) Query: 1129 GPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW------LKDDVLYETETLPNLERGI 1182 GP + +H E V+ VCK+ N + T W L++ YE E G+ Sbjct: 25263 GPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEI----TYEDGV 25318 Query: 1183 CELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK----VYDDMILAMSRVCGKSASPL 1238 L + ++K D G Y+ + +D G+D S E+ K VYD + + + Sbjct: 25319 AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTM 25378 Query: 1239 KVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL---QICEPTE 1295 ++L P L + K + + + + + W Q +P + Sbjct: 25379 RLLERPPEFTLPLYNK---------TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25429 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKN-RGRLIGGLPDVV 1354 DK KYTFE D L ++ D+ AE+ + E + + +L L Sbjct: 25430 NDK-KYTFE----SDKGLYQLTINSVTTDDD-AEYTVVARNKYGEDSCKAKLTVTLHPPP 25483 Query: 1355 T----------------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA 1398 T EG+++ V G P P + W K+ Q + L + + E Sbjct: 25484 TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGL 25543 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 Y ++ I+ ED+G Y + N G + V Sbjct: 25544 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580 Score = 58.9 bits (141), Expect = 3e-08 Identities = 104/506 (20%), Positives = 199/506 (39%), Gaps = 98/506 (19%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ T+ ++ W ++ E I D ++ I L +++ +D Y+VS+++ G Sbjct: 6354 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6413 Query: 990 VS----SSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDA 1045 + ++ +++ E+L + PLK E +K V FW + L+ Sbjct: 6414 ENVKSAANLIVEEEDLRIVE-----------PLKD---IETMEKKSVTFWCKVNRLN--V 6457 Query: 1046 SYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVL 1105 + ++ N EV + DK ++ + F +EG Y V G+ KS + L++ Sbjct: 6458 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFP--DEGEYIVTA--GQDKSVAELLI 6513 Query: 1106 IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW-- 1163 I EA + E L Q VTE + C+++ K KW Sbjct: 6514 I---------EAPTEFVEHLEDQ----------TVTEFDDAVFSCQLSREKANV--KWYR 6552 Query: 1164 ----LKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219 +K+ Y+ E ++ R L+I D EY ++D + + A Sbjct: 6553 NGREIKEGKKYKFEKDGSIHR----LIIKDCRLDDECEYACGVEDRKSR-------ARLF 6601 Query: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279 +++ + + R P +L P G + + D+++V W + + + ++ Sbjct: 6602 VEEIPVEIIR------PPQDILEAP-GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQM 6654 Query: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 ++ LQIC+ +D+G+Y F D EA A+ + A Sbjct: 6655 MSEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIK 6698 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 ++ ++ DV GK L + P E WFK ++ + ++ EQ Sbjct: 6699 TADQDLVV----DV-----GKPLTMVVPYDAYPKAEAEWFKENEPLS-TKTIDTTAEQTS 6748 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + K D G+Y I ++NK+G Sbjct: 6749 FRILEAK---KGDKGRYKIVLQNKHG 6771 Score = 58.5 bits (140), Expect = 4e-08 Identities = 36/101 (35%), Positives = 61/101 (60%), Gaps = 6/101 (5%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + RL+S TV + V+L V G PTPVV++Y+DG+ I + + ++I +++ Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEE 254 L I A +D+ TYS ATN+ G+ ++ A ++V +G+EE Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV---QGEEE 198 Score = 58.2 bits (139), Expect = 6e-08 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207 E IS P I+ L+ TV K G P P W KDG I Q GKY++ Sbjct: 26541 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG---GKYKLSE 26597 Query: 208 NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253 + G LEI++ D D+ Y+ N+ G VS++ + ++ + E Sbjct: 26598 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTE 26643 Score = 57.0 bits (136), Expect = 1e-07 Identities = 109/586 (18%), Positives = 215/586 (36%), Gaps = 97/586 (16%) Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--------PGTKEISAGVDEQG 924 KV +GK + +R V G+ T++ A TK + E+G Sbjct: 5935 KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 5994 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 + +C+ + ++ W K+ EI ++++I G KL + + ED+ TY+ Sbjct: 5995 ATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 6053 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPD 1044 D S + + P +E L L++ ++ +K RF + E + Sbjct: 6054 KDFK-TSCNLNVVPPHVEFLRPLTD--------------LQVREKEMARF--ECELSREN 6096 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 A ++ + E+ + + I A I +V+++ +++E Y+ ++ + Sbjct: 6097 AKVKWFKDGAEIKKGKKYDIISKGAVRI--LVINKCLLDDEAEYSCEVRTART------- 6147 Query: 1105 LIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL 1164 TVLEE K + +V+E ++LVC+V+ E + W Sbjct: 6148 ---SGMLTVLEEEAVFTKNL-----------ANIEVSETDTIKLVCEVSKPGAEVI--WY 6191 Query: 1165 K-DDVLYETETLPNLERGICELL-IPKLSKKDHGEYKATLKDDRGQ-DVSILEIAGKVYD 1221 K D+ + ET L G +L I +D G Y L R V + E+A + Sbjct: 6192 KGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFI- 6250 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGG 1281 L++L EG + + + V W D + S + + Sbjct: 6251 -----------SKPQNLEIL---EGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIA 6296 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + L + + T +D G Y + + AA Sbjct: 6297 DGKKRVLVVKDATLQDMGTYVVMVGAAR------------------------AAAHLTVI 6332 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV 1401 + R++ L D + E + + C V + WF+N++ I S + + + Y Sbjct: 6333 EKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY- 6389 Query: 1402 SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 ++ I+ +D Y++++ N + GE + ++ E + + P Sbjct: 6390 TLRIRDAHLDDQANYNVSLTN-HRGENVKSAANLIVEEEDLRIVEP 6434 Score = 56.2 bits (134), Expect = 2e-07 Identities = 98/501 (19%), Positives = 188/501 (37%), Gaps = 63/501 (12%) Query: 948 EEISD----DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EEIS E K+ KL LK + L + V S + S V EE+ + Sbjct: 26665 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIV--HEEITK 26722 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 S E++ +K+ ++G+ R L+A +++ ++++N E+++SE +R Sbjct: 26723 TSQASEEVRTHA-EIKAFSTQMSINEGQ-RLVLKA-NIAGATDVKWVLNGVELTNSEEYR 26779 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 + + + E T + +G K Q L L KE Sbjct: 26780 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL---------------SKE 26824 Query: 1124 FLRKQGPHF-AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERG- 1181 P F ++ ++ E V C+++ + +W K+++ + ++ R Sbjct: 26825 L--SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEI-EWFKNNLPISISSNVSISRSR 26881 Query: 1182 -ICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKV 1240 + L I S D G+Y K+ RGQ + + M+L + + V Sbjct: 26882 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL-------MVLPLVEEPSREV----V 26930 Query: 1241 LCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGK 1300 L T LQ + + ++++ ++A SS EM + + + Sbjct: 26931 LRTSGDTSLQG--SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM-- 26986 Query: 1301 YTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG-----RLIGGLPDVVT 1355 + +++S +F + Q +++ G I LP ++ Sbjct: 26987 -----------QESFVEMSSSSF-MGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDIS 27034 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVTSEDSG 1414 I EGK L + C G P PEV W + I E +E ++ I V +D G Sbjct: 27035 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGG 27094 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 Y++++ N++G + V + + Sbjct: 27095 LYTLSLGNEFGSDSATVNIHI 27115 Score = 55.5 bits (132), Expect = 4e-07 Identities = 40/202 (19%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Query: 1247 IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIF 1306 ++ C ++ + +V W ++ +SE I + +A L + + T+ D G Y ++ Sbjct: 25280 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25339 Query: 1307 DGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK-NRGRLIGGLPDVV------TIMEG 1359 + +L + E + + + + + RL+ P+ T G Sbjct: 25340 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25399 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH---FSVKVEQAKYVSMTIKGVTSEDSGKY 1416 + + T+ +P+P V W+K+ Q I+ ++ ++ + ++ Y +TI VT++D +Y Sbjct: 25400 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEY 25458 Query: 1417 SINIKNKYGGEKIDVTVSVYKH 1438 ++ +NKYG + ++V H Sbjct: 25459 TVVARNKYGEDSCKAKLTVTLH 25480 Score = 55.5 bits (132), Expect = 4e-07 Identities = 69/264 (26%), Positives = 108/264 (40%), Gaps = 19/264 (7%) Query: 12 RHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLS-QRSSSQRASSQTSLGGTICRV 70 R S Q + L E ASK S + + S ++S ++TS R Sbjct: 26673 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRT 26732 Query: 71 CA--KRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEE--------DVHLARS 120 A K STQ + R ++ +A + K EL + EE D L Sbjct: 26733 HAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK 26792 Query: 121 QA--RDKLDKYAIQQMMEDKLAWERH-TFEERISRAPEILVRLRSHTVWERMSVKLCFTV 177 QA RD+ I + E + + T + +S AP + + RS + E +V + Sbjct: 26793 QASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI 26852 Query: 178 QGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQ 237 G P+P ++W+K+ I ++ I + V++LEI A D+ Y+ A N GQ Sbjct: 26853 SGEPSPEIEWFKNNLPISISS---NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ 26909 Query: 238 VSTNAAVVVRRFRGDEEPFRSVGL 261 S A+++V EEP R V L Sbjct: 26910 CSATASLMVLPL--VEEPSREVVL 26931 Score = 55.1 bits (131), Expect = 5e-07 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 +P+ +TI GK L + V+G P P W K + ++ S H +V + + + IK VT Sbjct: 12599 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVT 12657 Query: 1410 SEDSGKYSINIKNKYG--GEKIDVTV 1433 +DSG YS+ +N G +KI V V Sbjct: 12658 RKDSGYYSLTAENSSGTDTQKIKVVV 12683 Score = 54.7 bits (130), Expect = 6e-07 Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 29/243 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P ++ L++ TV E SV L + G+P+P V WY++ I + + ++I G+ Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIAR 953 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVR--------------RFRGDEEPFRS- 258 L I A +D+ ++ A N G VST+ + V+ +F +E+ F Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013 Query: 259 ---VGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAE 315 V L P F+ K V EG +V C + P +P Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVY 1068 Query: 316 WYRDDVLLKESKWTKMFFGE--GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W + V L K+ + + G+ L S DD G YT+ + ++ G + SA L + Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LE 1127 Query: 374 DAD 376 +AD Sbjct: 1128 EAD 1130 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L+ GL +V T++EG+++ L C + G P P V W++ D I+ S F + Q+ + I Sbjct: 899 LVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMI 956 Query: 1406 KGVTSEDSGKYSINIKNKYG 1425 + +EDSG+++ + N+ G Sbjct: 957 REAFAEDSGRFTCSAVNEAG 976 Score = 52.0 bits (123), Expect = 4e-06 Identities = 51/223 (22%), Positives = 91/223 (40%), Gaps = 31/223 (13%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 ++AP L+S V E + + GFP P V W++DG +I + PG +I + G Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPG-VQISFSDG 61 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 L I ++ YS ATN GQ ++ A ++V + + P Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV---KAETAP--------------- 103 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 F+++ R+G V L+ + P P ++YRD ++ S + Sbjct: 104 -------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLDFQ 151 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 + SL + + +D G Y++ + G + +A L V+ Sbjct: 152 ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 52.0 bits (123), Expect = 4e-06 Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 27/207 (13%) Query: 1245 EGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFE 1304 E + L+C + + V W +D +I SS +I +A L I E +D G++T Sbjct: 912 ESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 970 Query: 1305 IFDGKDNHQRSLDLSGQAFDE-----------------AFAEFQQ--FKAAAFAEKNRGR 1345 + S L+ Q +E F E + + E+ G Sbjct: 971 AVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGP 1030 Query: 1346 LIGGLPDVVT------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKV-EQA 1398 P +T ++EG ++ C V GNP P V W K+ + + V +Q Sbjct: 1031 GEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + I ++D+G+Y+I ++NK+G Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHG 1117 Score = 50.8 bits (120), Expect = 9e-06 Identities = 113/619 (18%), Positives = 230/619 (37%), Gaps = 109/619 (17%) Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---GTKEISAGVDEQGNIYL 928 L + D+ + V+A+N G + + +LV+A+ T+E+ V ++ + Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAG---ETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146 Query: 929 GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 F+C+ + W K E+ + +++++ + L + D D YS + + + Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE 2206 Query: 989 GVSSS-----------FVLDPEELERLMALSNEIK-------------NPTIPLKSELAY 1024 V ++ FV + +++E + S E++ + + LKS Y Sbjct: 2207 NVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKY 2266 Query: 1025 EIFDK-GRVRFWLQAEHLSPDASYRFIIN----------------------DREVSDSEI 1061 I + GR ++ Y F+I+ D++V + +I Sbjct: 2267 TITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDI 2326 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +++ + +E V + E + + V I K QS ++LI D K F Sbjct: 2327 VQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK---QSHMLLIEDMTKEDAGNYSFTI 2383 Query: 1122 KEFLRKQGPHFAEYL--------HWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE 1173 + Y +V E + L CKV+ +V +L D+ + + Sbjct: 2384 PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDD 2443 Query: 1174 TLPNLERGICE-LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCG 1232 + + +G + L+I + D G YK I G+V + L++ ++ Sbjct: 2444 RVQAIVKGTKQRLVINRTHASDEGPYKL--------------IVGRVETNCNLSVEKI-- 2487 Query: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 K L+ L E + ++ + V W KD +I S +I ++ L + Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLN 2547 Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352 + D+GKYTF + G++ L ++G A + + Sbjct: 2548 MMKDDEGKYTF--YAGENMTSGKLTVAGGAISKPLTD----------------------- 2582 Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 T+ E + C V NPD + W ++ + + L+ + + + K + I +D Sbjct: 2583 -QTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKR-RLIIAATKLDD 2639 Query: 1413 SGKYSINIKNKYGGEKIDV 1431 G+Y+ + K+ V Sbjct: 2640 IGEYTYKVATSKTSAKLKV 2658 Score = 50.1 bits (118), Expect = 2e-05 Identities = 85/412 (20%), Positives = 150/412 (36%), Gaps = 66/412 (16%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K +E+ +R KI+ +L + + D G Y+V Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVS 3090 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASY-- 1047 + FV + R+ ++ E+ ++ +K R + DA + Sbjct: 3091 TAKLFVEGRDV--RIRSIKKEV-------------QVIEKQRAVVEFEVNEDDVDAHWYK 3135 Query: 1048 -----RFIINDRE--VSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQ 1100 F + +R V + IHR M + + G YT +++ Sbjct: 3136 DGIEINFQVQERHKYVVERRIHR-----------MFISETRQSDAGEYTFVA----GRNR 3180 Query: 1101 SSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETV 1160 SS+ L +A + P + L + + C V + + + Sbjct: 3181 SSVTLYVNA-----------------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPK 3223 Query: 1161 FKWLKDDVLYETETLPNLERGICE--LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218 W K++ L T E LL+ + +D Y K+D G + ++ + Sbjct: 3224 ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283 Query: 1219 VYDDMILAMSRVCGKSA--SPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSS 1274 V + + A +PL+ T EG R QC + ++KV+W KD KI S Sbjct: 3284 VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQC--RVSGTDLKVSWYSKDKKIKPS 3341 Query: 1275 EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFD--GKDNHQRSLDLSGQAFD 1324 R+ E+ L+I E +D+G YTF + G+ + +L L QA D Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALD 3393 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 6/107 (5%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P +T+ EG++ +C G P P V W + Q + S V + K + I V + Sbjct: 26262 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQA 26320 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA---PPQQAKPK 1454 D G YS+ ++N G ++ + T+++ K ++ + A PP+ P+ Sbjct: 26321 SDEGNYSVVVENSEGKQEAEFTLTIQK--ARVTEKAVTSPPRVKSPE 26365 Score = 48.9 bits (115), Expect = 4e-05 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P+ V ++EG+T C V G P P+V W+ N Q I+ S+ F V+ + Y + I S Sbjct: 1801 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY--LDIVDCKS 1858 Query: 1411 EDSGKYSINIKNKYG 1425 D+G+ + +N G Sbjct: 1859 YDTGEVKVTAENPEG 1873 Score = 48.5 bits (114), Expect = 5e-05 Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 26/207 (12%) Query: 1261 KVNWCHKDAKISSSE--HMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDL 1318 +V+W IS+S ++I S+ A L I T+ + G+Y+ + +G Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNG---------- 85 Query: 1319 SGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIW 1378 SGQA A + AE + L + T+ +G + L V G P P V + Sbjct: 86 SGQATSTA-------ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKF 137 Query: 1379 FKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKH 1438 +++ +IQ S F + E Y S+ I EDSG YS+N N G + T + Sbjct: 138 YRDGAEIQSSLDFQISQEGDLY-SLLIAEAYPEDSGTYSVNATNSVG--RATSTAELLVQ 194 Query: 1439 GEKIPDMAPPQQAKPKLIPASASAAGQ 1465 GE + P ++ K + A S + Q Sbjct: 195 GE---EEVPAKKTKTIVSTAQISESRQ 218 Score = 48.5 bits (114), Expect = 5e-05 Identities = 124/606 (20%), Positives = 230/606 (37%), Gaps = 106/606 (17%) Query: 832 LWKAPVYSGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 L+ V+ G + + + ++ E D G+W Q TA+ ++ ++ GK ++ + Sbjct: 5452 LYGVEVFVGET--AHFEIELSEPDVHGQWKLKGQPLTASPDCEI--IEDGKKHILILHNC 5507 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEIS-------AGVDEQGNIYLGFDCQEMTDASQFTW 943 G+ S + A KE+ + V F+C+ + F W Sbjct: 5508 QLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRW 5567 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 K +EI+ D+RF++ G + +K+ ED Y D S +++ L+ Sbjct: 5568 LKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH-TSGKLIIEGIRLKF 5626 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 L PLK A E K F ++ H + ++ ND+ + + Sbjct: 5627 L-----------TPLKDVTAKE---KESAVFTVELSH--DNIRVKWFKNDQRLHTTRSVS 5670 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 ++ + T I SI++ V+ ++ + +A TVLE Sbjct: 5671 MQDEGKTHSI--TFKDLSIDDTSQIRVE----------AMGMSSEAKLTVLE-------- 5710 Query: 1124 FLRKQGPHFAEYLH-WDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETETLPNLER 1180 P+F L + E+ EV L C++ +K + KW KD ++ + + Sbjct: 5711 ----GDPYFTGKLQDYTGVEKDEVILQCEI--SKADAPVKWFKDGKEIKPSKNAVIKADG 5764 Query: 1181 GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV-YDDMILAMSRVCGKSASPLK 1239 L++ K K D G+Y D G D + +GK+ +D + + R PL Sbjct: 5765 KKRMLILKKALKSDIGQYTC----DCGTD----KTSGKLDIEDREIKLVR-------PLH 5809 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 + E + + D++ NW K A LQ + K++G Sbjct: 5810 SVEVMETETARFETEISEDDIHANWKLKGE----------------ALLQTPDCEIKEEG 5853 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE-KNRGRLIGGLPDV--VTI 1356 K + H LD +G +FQ + A + + R+IG L + VT+ Sbjct: 5854 KIHSLVL-----HNCRLDQTGG------VDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5902 Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 G+T C + D V W+ + ++ S+ V + K ++T++ V ED+G+ Sbjct: 5903 TAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKV-VPRSEGKVHTLTLRDVKLEDAGEV 5960 Query: 1417 SINIKN 1422 + K+ Sbjct: 5961 QLTAKD 5966 Score = 48.5 bits (114), Expect = 5e-05 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D +TI G+ LT G P P+V WFK++ D+ + +K A IK S Sbjct: 10521 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRS- 10579 Query: 1412 DSGKYSINIKNKYGGEK 1428 DSGKY + ++N G K Sbjct: 10580 DSGKYCVVVENSTGSRK 10596 Score = 48.5 bits (114), Expect = 5e-05 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G++ + ++G P P + W K DQ++ + +K S+++K Sbjct: 16246 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFA-TSLSVKDAVRV 16304 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y + KN G + V V V Sbjct: 16305 DSGNYILKAKNVAGERSVTVNVKV 16328 Score = 48.5 bits (114), Expect = 5e-05 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 15/145 (10%) Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQA-FDEAFAEFQQFKAAAFAEKNRGRLIGGLP 1351 P K KY+F + ++++ G + + E+ AE + + + L L Sbjct: 23100 PDLKMGQKYSFRV--------AAVNVKGMSEYSESIAEIEPVERIEIPDLE---LADDLK 23148 Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 VTI G +L L +V G P P + W K Q I L+ + ++ Y + + V Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTES-YSLLIVDKVNRY 23205 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSVY 1436 D+GKY+I +N+ G + V V VY Sbjct: 23206 DAGKYTIEAENQSGKKSATVLVKVY 23230 Score = 48.1 bits (113), Expect = 6e-05 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V I EG L + GNP+P+++W KN I ++ +++E K ++ I S+D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIP 1457 S Y+ NK G + V+V + A P+ + +IP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVE------VEFAEPEPERKLIIP 1617 Score = 48.1 bits (113), Expect = 6e-05 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L ++ I G +L L + G P PEV W K D +I+ + V + + S+ + V Sbjct: 16643 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT---SSFTSLVLDNVN 16699 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ ++N G + VTV V Sbjct: 16700 RYDSGKYTLTLENSSGTKSAFVTVRV 16725 Score = 47.4 bits (111), Expect = 1e-04 Identities = 91/436 (20%), Positives = 177/436 (40%), Gaps = 67/436 (15%) Query: 999 EELERLMALSNEIKNPTI-PLKSEL-----AYEIFDKGRVRFWLQAEHLSPDASYRFIIN 1052 EE ++ +A +I PT P K EL A +IF+ R Q DA +R + Sbjct: 2001 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFE----RIQSQTVGQGSDAHFRVRVV 2056 Query: 1053 DREVSDSEIHR--IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAF 1110 + + E ++ +K +++ I + + + I D A+ +S+++ Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIY------WYWPEDNVCELVIRDVTAEDSASIMV----- 2105 Query: 1111 KTVLEEAEFQRKEFLRKQGPH---FAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDD 1167 K + E FL Q F + L V +E + + ++ KW KD Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Query: 1168 V-LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRG-QDVSILEIAGKVYDDMI 1224 + ++E + + +R + L I + D +Y L +D + + L + G V + + Sbjct: 2166 MEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV- 2224 Query: 1225 LAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEE 1284 K ++V + G L+C + + ++ W H D ++ S+ I Sbjct: 2225 --------KELQDIEVPESYSG-ELECIVS--PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1285 MAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG 1344 L + + T++D+G+Y+F + DGK + + K A Sbjct: 2274 RQNLTVKDVTKEDQGEYSF-VIDGKKTTCK----------------LKMKPRPIA----- 2311 Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 ++ GL D + EG + L V E +W K+ Q++Q S+ + +++ ++ + Sbjct: 2312 -ILQGLSD-QKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHM-LL 2367 Query: 1405 IKGVTSEDSGKYSINI 1420 I+ +T ED+G YS I Sbjct: 2368 IEDMTKEDAGNYSFTI 2383 Score = 47.0 bits (110), Expect = 1e-04 Identities = 116/553 (20%), Positives = 198/553 (35%), Gaps = 103/553 (18%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS--VSVSDT 987 F+C + TW K I + + + G KL++ + D G Y+ + + + Sbjct: 4833 FECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4892 Query: 988 DGVSSSFVLDPEELERLMALSNE----IKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 + S++ ++ E R + E +K + L EL +K R W + + Sbjct: 4893 EKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL-----NKERDVVWRKDGKIVV 4947 Query: 1044 DASYRFI-----------INDREVSDS--------EIHRIKCDKATGIIEMVMDRFSIEN 1084 + R + IND + +D+ + ++C ++E++ D Sbjct: 4948 EKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL---- 5003 Query: 1085 EGTYTVQIHDGKAKSQSSLVLIGDAFKTVLE----------EAEFQRKEFLRKQGPHF-- 1132 I D K + + + D K AE K + + G H Sbjct: 5004 ----VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYL 5059 Query: 1133 --AEYLHWDVTE---ECE-VRLVCKVANTKKET-VFKWLKDDVLYETET----------- 1174 + D+ E E E R K+ ++E + K ++D +YE E+ Sbjct: 5060 KIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD 5119 Query: 1175 LPNLERGICELLIPKLS---KKDHGEYKATL-KDDRGQDVSILEIAGKVYDDMILAMSRV 1230 +P + ELL P + K + G+ TL K Q +L A IL + + Sbjct: 5120 IPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEI 5179 Query: 1231 CGKSASPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL 1288 A PLK + PE R +C + T E V W I SS+ I + L Sbjct: 5180 ELDFAVPLKDVTVPERRQARFECVL---TREANVIWSKGPDIIKSSDKFDIIADGKKHIL 5236 Query: 1289 QICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIG 1348 I + D+G YT E+ E ++ A F R + + Sbjct: 5237 VINDSQFDDEGVYTAEV-----------------------EGKKTSARLFVTGIRLKFMS 5273 Query: 1349 GLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 L D T+ EG+T C + + V+WFKND + S + E K + +K V Sbjct: 5274 PLEDQ-TVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSE-GKTHKLEMKEV 5330 Query: 1409 TSEDSGKYSINIK 1421 T +D + +K Sbjct: 5331 TLDDISQIKAQVK 5343 Score = 47.0 bits (110), Expect = 1e-04 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+T+ G+T+ + V G P+P++ W K + + + + ++ V + IK Sbjct: 11611 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRA 11669 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY I+ KN G + V+V Sbjct: 11670 DHGKYIISAKNSSGHAQGSAIVNV 11693 Score = 47.0 bits (110), Expect = 1e-04 Identities = 48/209 (22%), Positives = 81/209 (38%), Gaps = 22/209 (10%) Query: 1238 LKVLCTPEGIRLQCFMKYFTDEMK-VNWCHKDAKISSSEHMRIGGSEEMAW-LQICEPTE 1295 LK + E +L C ++ K V W K+ + H + S + + L+I TE Sbjct: 26419 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26478 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAF----------DEAFAEFQQFKAAAFAEKNRGR 1345 D+G+Y EI + +L GQAF E Q+ + K + Sbjct: 26479 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26538 Query: 1346 L---IGGLPDVVTIMEGKTLN------LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE 1396 I P +VT ++ T++ G P P IW K+ + I + + + Sbjct: 26539 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSED 26598 Query: 1397 QAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + + I + DSG Y+ +KN G Sbjct: 26599 KGGFF-LEIHKTDTSDSGLYTCTVKNSAG 26626 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 +LI GL + G T+ + G P P W + +I+ EH++V+ + V +T Sbjct: 11210 KLIEGL----VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LT 11264 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 IK D+G+Y I + N G + + V ++V Sbjct: 11265 IKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295 Score = 45.8 bits (107), Expect = 3e-04 Identities = 24/79 (30%), Positives = 39/79 (49%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 +EG+T V G P PE WF + Q I V +++ S+ I T DSG++ Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482 Query: 1417 SINIKNKYGGEKIDVTVSV 1435 ++ +N+ G I V ++V Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501 Score = 45.8 bits (107), Expect = 3e-04 Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 37/177 (20%) Query: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 P V+WYKDG + E KYR+ S+ VH L I D D YS V V T Sbjct: 2155 PFVKVKWYKDGM---EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKT 2210 Query: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 A ++V +++ + V+ L+ V GE L+C Sbjct: 2211 TAKLIVE--------------------GAVVEF----VKELQDIEVPESYSGE---LEC- 2242 Query: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRI 357 +V+P+ +WY +DV LK + + G+ +L+ + K+D+G Y+ I Sbjct: 2243 -IVSPE----NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI 2294 Score = 45.8 bits (107), Expect = 3e-04 Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 25/202 (12%) Query: 1257 TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEP-TEKDKGKYTFEIFDGKDNHQRS 1315 T+ +VNW ++ + S E + + L I + TE +G+Y E + Sbjct: 4459 TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCE----------A 4508 Query: 1316 LDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375 L+ SG+ A + K AA K + + + + G TC + P+ Sbjct: 4509 LNDSGKTATSA--KLTVVKRAAPVIKRK-------IEPLEVALGHLAKFTCEIQSAPNVR 4559 Query: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 WFK ++I S+ S++ +KY+ S+ I D G+Y+ N+YG T++ Sbjct: 4560 FQWFKAGREIYESDKCSIR--SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 4617 Query: 1435 VYKHG--EKIPDMAPPQQAKPK 1454 V G +K+ + P ++ +PK Sbjct: 4618 VTVPGGEKKVRKLLPERKPEPK 4639 Score = 45.8 bits (107), Expect = 3e-04 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VV + TL L T+ G P+PEV W K + L++ ++V + + + I VT Sbjct: 18808 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEG--ILTDRAQIEV-TSSFTMLVIDNVT 18864 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSG+Y++ ++N G + V V V Sbjct: 18865 RFDSGRYNLTLENNSGSKTAFVNVRV 18890 Score = 45.4 bits (106), Expect = 4e-04 Identities = 86/402 (21%), Positives = 144/402 (35%), Gaps = 53/402 (13%) Query: 12 RHRHFDQSYR-NIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRV 70 R F+ +Y+ I Y DE AS S + S +A + S G + R Sbjct: 3345 RMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDV-RE 3403 Query: 71 CAKRVSTQEDE--EQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDK 128 AK + + ++E++ + + + G + + + +H A S +L Sbjct: 3404 SAKSQAVADSSFTKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCH 3463 Query: 129 YAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWY 188 A + + + +E AP+I + L+ TV + + ++ V W Sbjct: 3464 TASLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWT 3523 Query: 189 KDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRR 248 +G+ I E + + N + L I D YS + N G+ +T+A + V Sbjct: 3524 HEGAKI---EESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEG 3580 Query: 249 -------------------------FRGDEEPFRSVGLPIG-----LPLSSMIPY--THF 276 +EE S L + L L S P T F Sbjct: 3581 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKF 3640 Query: 277 DVQFLEKFGVTFRRE--------GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 D + E G F +E G+ TL T++ P +P+ +W+ + VLL S Sbjct: 3641 DSE-KEGTGPIFIKEVSNADISMGDVATLSVTVIGIP-----KPKIQWFFNGVLLTPSAD 3694 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 K F SL +DEG YT + G + SA+L Sbjct: 3695 YKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 3736 Score = 45.4 bits (106), Expect = 4e-04 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 I G TL L+ + G P P+V W K D+D V +K + I+ ED G Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10981 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 YS+ ++N G + + V V V Sbjct: 10982 YSLTVENPAGSKTVSVKVLV 11001 Score = 45.1 bits (105), Expect = 5e-04 Identities = 91/479 (18%), Positives = 176/479 (36%), Gaps = 75/479 (15%) Query: 943 WCKSYEEISDDERFKIETVGDH-SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEEL 1001 W K+ +I +R D+ +L +++ ED + V + G +SS + Sbjct: 2065 WYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Query: 1002 ERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEI 1061 ++L+ + E+++ K +A + E P ++ + EV + + Sbjct: 2125 KQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGMEVHEGDK 2173 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +R+ D+ + ++ S + E V + D K+ + L++ G + V E + + Sbjct: 2174 YRMHSDRKVHFLSILTIDTS-DAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIE- 2231 Query: 1122 KEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--E 1179 V E L C V+ E KW +DV ++ + Sbjct: 2232 ------------------VPESYSGELECIVSPENIEG--KWYHNDVELKSNGKYTITSR 2271 Query: 1180 RGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLK 1239 RG L + ++K+D GEY + D + + + L+ +VC Sbjct: 2272 RGRQNLTVKDVTKEDQGEYSFVI-DGKKTTCKLKMKPRPIAILQGLSDQKVC-------- 2322 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 EG +Q +K + ++ W ++ S+ + I ++ L I + T++D G Sbjct: 2323 -----EGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAG 2377 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEG 1359 Y+F I +L LS ++ +I L D V ++EG Sbjct: 2378 NYSFTI--------PALGLSTSGRVSVYSV---------------DVITPLKD-VNVIEG 2413 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 L C V V W+ ND+ I+ + V+ K + I + D G Y + Sbjct: 2414 TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ-RLVINRTHASDEGPYKL 2471 Score = 45.1 bits (105), Expect = 5e-04 Identities = 21/84 (25%), Positives = 42/84 (50%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+T L + G P P+V+W K+ ++++ + + ++ +K Sbjct: 18410 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18469 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + + N G + I +TV V Sbjct: 18470 DGGQYILKLSNVGGTKSIPITVKV 18493 Score = 44.7 bits (104), Expect = 7e-04 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V ++EG T + G P PEV WF++ Q I S V++ + +TI VT + Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74 Query: 1413 SGKYSINIKNKYG 1425 SG+YS+ N G Sbjct: 75 SGRYSLKATNGSG 87 Score = 44.7 bits (104), Expect = 7e-04 Identities = 113/572 (19%), Positives = 200/572 (34%), Gaps = 122/572 (21%) Query: 940 QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPE 999 + +W K + +S + K G L L ED Y+ + GV+++ Sbjct: 3223 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282 Query: 1000 ELERLMALSNEIKNPTIPLKSELAYEIFDKGR-VRFWLQAEHLSPDASYRFIINDREVSD 1058 E+ +++ E+ + + L + +G+ RF Q D + D+++ Sbjct: 3283 EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF--QCRVSGTDLKVSWYSKDKKIKP 3340 Query: 1059 SEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHD--GKAKSQSSLVL----------- 1105 S R+ + T +E+ E+EGTYT + G+ S ++L L Sbjct: 3341 SRFFRMTQFEDTYQLEIA--EAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSG 3398 Query: 1106 -----------IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVAN 1154 + D+ T EE++ +KE QG + E EV++ V+ Sbjct: 3399 KDVRESAKSQAVADSSFTK-EESKISQKEIKSFQGSSY----------EYEVQVFESVSQ 3447 Query: 1155 TKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILE 1214 + T ++D L T +L + +LSK+ K+ G+ Sbjct: 3448 SSIHTAAS-VQDTQLCHTASLSQIAEST------ELSKE-------CAKESTGE------ 3487 Query: 1215 IAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS 1274 A K++ L + V K + LC + F D V W H+ AKI S Sbjct: 3488 -APKIF----LHLQDVTVKCGDTAQFLCVLKD-------DSFID---VTWTHEGAKIEES 3532 Query: 1275 EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFA------ 1328 E ++ + + +L IC D+G Y+ + + S LS + E+ Sbjct: 3533 ERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQ 3592 Query: 1329 ----EFQQFKAAAFAEKNRG---------------RLIGGLPDVVT-------------- 1355 E ++F ++ + + G L+ P T Sbjct: 3593 EIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFI 3652 Query: 1356 -------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 I G L+ TV G P P++ WF N + S + + + S+ I Sbjct: 3653 KEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFT 3711 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSVYKHGE 1440 ED G+Y+ N YG + + GE Sbjct: 3712 KLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3743 Score = 44.7 bits (104), Expect = 7e-04 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + I G++L + V G P P V WFK+ +I+ + + + S+ ++ T + Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRD 21719 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 G Y++ KN G K ++ V V Sbjct: 21720 HRGVYTVEAKNASGSAKAEIKVKV 21743 Score = 44.3 bits (103), Expect = 9e-04 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G+T L V G P P + W + D++I+ S +K K + + +K Sbjct: 17328 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL-LIVKDAIRI 17386 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + N G + V V V Sbjct: 17387 DGGQYILRASNVAGSKSFPVNVKV 17410 Score = 43.9 bits (102), Expect = 0.001 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E SV V G P P ++W KDG + + P I + L I +DT Sbjct: 25503 EGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25560 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRS 258 Y ATN G S A + V R R ++ F+S Sbjct: 25561 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKS 25592 Score = 43.5 bits (101), Expect = 0.001 Identities = 60/266 (22%), Positives = 105/266 (39%), Gaps = 54/266 (20%) Query: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238 G PT VV+W DG + A + R+ + +G +L+ A D+ + ATN +G Sbjct: 1684 GDPTMVVEWLHDGKPLEAA---NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTD 1740 Query: 239 STNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF----------GVTF 288 T+A ++V+ DE+ L S +P +Q +E+ GVT Sbjct: 1741 HTSATLIVK----DEK---------SLVEESQLPEGRKGLQRIEELERMAHEGALTGVTT 1787 Query: 289 RR------------------EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 + EGET +C + P QP+ WY + L+++SK + Sbjct: 1788 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFR 1842 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR---DADPLVTGAPGAPM 387 + + +G L D G + + GV +H L ++ D ++ AP Sbjct: 1843 VRY-DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1901 Query: 388 DLQCHDANR-DYVIVTWKPPNTTTES 412 + H+ + + + P TTE+ Sbjct: 1902 EFHVHEPGKLQFEVQKVDRPVDTTET 1927 Score = 43.5 bits (101), Expect = 0.001 Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 8/141 (5%) Query: 107 ELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVW 166 EL H +++ +A + K I DK+ AP+I R++S TV Sbjct: 1991 ELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSM------EAPKIFERIQSQTVG 2044 Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 + V G P P +WYK+G I ++ Y E N V L I +D+A+ Sbjct: 2045 QGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN--VCELVIRDVTAEDSAS 2102 Query: 227 YSAVATNAHGQVSTNAAVVVR 247 A N G+ S++A ++V+ Sbjct: 2103 IMVKAINIAGETSSHAFLLVQ 2123 Score = 43.5 bits (101), Expect = 0.001 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G + +T G P P V+W K D D++ + + S+TI+ DSGK Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRT---SLTIENANRNDSGK 19949 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ I+N + + V V Sbjct: 19950 YTLTIQNVLSAASLTLVVKV 19969 Score = 43.1 bits (100), Expect = 0.002 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM-FFGEGQASLSFSHLHKDD 349 EG VT C M P P+ WY+D +K + +M F +G+ASL + +D Sbjct: 1258 EGMGVTFHCKMSGYP-----LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAP 383 EG+YT + G + S L+V A PL GAP Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYVEPAAPL--GAP 1344 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%) Query: 145 TFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR 204 T +++ + P+I++ V E + + V G+P P V WY +G LI ++ ++R Sbjct: 1786 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK---RFR 1842 Query: 205 IESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSV 259 + + G+H L+I DT A N G + + +++ E FRSV Sbjct: 1843 VRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ----REDFRSV 1892 Score = 43.1 bits (100), Expect = 0.002 Identities = 80/376 (21%), Positives = 138/376 (36%), Gaps = 82/376 (21%) Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 VL E TK + A ++ + C+ ++ W K EEI + R++I T G Sbjct: 6153 VLEEEAVFTKNL-ANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6211 Query: 965 SKLYLKNPDKEDLGTYSVSV--SDTDG------VSSSFVLDPEELERLMALSNE----IK 1012 L ++N ED G Y+ + S TDG +++ F+ P+ LE L E I Sbjct: 6212 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 6271 Query: 1013 NPTIP---------LKSELAYEIFDKGRVRFWL--------------------QAEHLSP 1043 + P L+S Y++ G+ R + A HL+ Sbjct: 6272 KESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV 6331 Query: 1044 DASYRFII--NDREVSDSEIHRIKCDKATGII--------EMVMDR---FSIENEGTYTV 1090 R ++ D V + + C+ T E + D ++ + YT+ Sbjct: 6332 IEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTL 6391 Query: 1091 QIHDGKAKSQSSLVL---------IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVT 1141 +I D Q++ + + A ++EE + + E L+ + Sbjct: 6392 RIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLK----------DIETM 6441 Query: 1142 EECEVRLVCKVANTKKETVFKWLK--DDVLYETETLPNLERGICELLIPKLSKKDHGEYK 1199 E+ V CKV + KW K ++V ++ +++ L I D GEY Sbjct: 6442 EKKSVTFWCKV--NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI 6499 Query: 1200 ATLKDDRGQDVSILEI 1215 T GQD S+ E+ Sbjct: 6500 VT----AGQDKSVAEL 6511 Score = 43.1 bits (100), Expect = 0.002 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G ++ L G P P +W K D ++ L + ++T++ D+GK Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 22120 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ ++N G + I TV V Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE-QAKYVSMTIKGV 1408 L V+T+ G T+ L V G P PEV W K+ L+ VK++ +A ++ Sbjct: 11902 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11961 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY + N G TV+V Sbjct: 11962 KRSDGGKYVVTATNTAGSFVAYATVNV 11988 Score = 42.7 bits (99), Expect = 0.003 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + ++T+ G + L TVFG P P V W K+ ++ +E + + Q ++ + V Sbjct: 12996 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVN 13054 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 +DSG Y+I +N G + + + V Sbjct: 13055 RKDSGDYTITAENSSGSKSATIKLKV 13080 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 V + G+ +++ G PDP + W K I + H+ V V ++ + GV +D+ Sbjct: 24732 VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDA 24791 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 G Y + KN++G ++ V + V +PD PP+ K Sbjct: 24792 GFYVVCAKNRFGIDQKTVELDV----ADVPD--PPRGVK 24824 Score = 42.4 bits (98), Expect = 0.003 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+ L + + G P P + W K+ +I+ + + + +T+K Sbjct: 19492 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRR 19550 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D+G+Y + +KN G + V V Sbjct: 19551 DTGQYVLTLKNVAGTRSVAVNCKV 19574 Score = 42.0 bits (97), Expect = 0.004 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKN----DQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + IM GKTL + V G P P +W K D+D + ++ K E + IK Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8862 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 +D G+Y I N G + V V+ + D+ P Sbjct: 8863 RKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKP 8900 Score = 42.0 bits (97), Expect = 0.004 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 1350 LPDVVTIMEGKTLNLTC-TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 + D +TI G T+ L ++ G P P+ W K +DI+ S+ + + +TIK Sbjct: 14079 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYA 14137 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 T +D+G+Y+I N +G + V V+V Sbjct: 14138 TRKDAGEYTITATNPFGTKVEHVKVTV 14164 Score = 42.0 bits (97), Expect = 0.004 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G+ + L + G P P WF ++ SE +V+ K +TI+ T D+ Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH-TKVAKLTIRETTIRDT 23501 Query: 1414 GKYSINIKNKYG 1425 G+Y++ +KN G Sbjct: 23502 GEYTLELKNVTG 23513 Score = 41.6 bits (96), Expect = 0.006 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Query: 1349 GLPDVVTIM-EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 GLPD+ + E L + G P P V W K + + SV+ A ++ + Sbjct: 13681 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYD 13739 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+GKY+I +KN G ++ +++ V Sbjct: 13740 CQKSDAGKYTITLKNVAGTKEGTISIKV 13767 Score = 41.6 bits (96), Expect = 0.006 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VVTI TL L + G P PEV W ++ + + S++ + Y + + V Sbjct: 15561 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHG--ESLDKASIE-STSSYTLLIVGNVN 15617 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 DSGKY + ++N G + V V V + PPQ K K Sbjct: 15618 RFDSGKYILTVENSSGSKSAFVNVRV------LDTPGPPQDLKVK 15656 Score = 41.6 bits (96), Expect = 0.006 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 +VV G ++ L + G P P + W+K+D+++Q + V+ S+ IK Sbjct: 20575 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20633 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 +SG Y + ++N G + V + Sbjct: 20634 NSGCYELKLRNAMGSASATIRVQI 20657 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L G ++T G + + G P P+V W + ++ ++ S+ + + ++T+ Sbjct: 22344 LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDR-TTLTV 22402 Query: 1406 KGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 K DSG+Y + ++N G + VTV V Sbjct: 22403 KDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432 Score = 40.8 bits (94), Expect = 0.010 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%) Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 W+ EP + K + T + +GK R L+ Q + ++ +A E L Sbjct: 7329 WVACGEPVAETKMEVT-GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7387 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIK 1406 L +T+ G + L TV G P+P++ W K D ++ + +++ K ++TI Sbjct: 7388 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIV 7446 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+G Y I N G V V+V Sbjct: 7447 DSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475 Score = 40.4 bits (93), Expect = 0.013 Identities = 68/297 (22%), Positives = 116/297 (39%), Gaps = 49/297 (16%) Query: 1150 CKVANTKKETVFKWLKDDVL----YETETLPNLERGICELLIPKLSKKDHGEYKATLKDD 1205 C+V K V+ W K V Y + N + G C+L+I D GEY +++ Sbjct: 1057 CQVGGNPKPHVY-WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNK 1115 Query: 1206 RGQ---DVSILEIAG-----KVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFT 1257 G+ S+LE A K +M L ++V P KV T G + K + Sbjct: 1116 HGETSASASLLEEADYELLMKSQQEM-LYQTQVTAFVQEP-KVGETAPGFVYSEYEKEYE 1173 Query: 1258 DEMKV--NWCHKDAKISSS----EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDN 1311 E + KD + + + I EE ++ + E K T E +D Sbjct: 1174 KEQALIRKKMAKDTVVVRTYVEDQEFHISSFEE----RLIKEIEYRIIKTTLEELLEEDG 1229 Query: 1312 HQR-SLDLS-GQAFDEAF-AEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTV 1368 ++ ++D+S +A + F + + ++ I+EG + C + Sbjct: 1230 EEKMAVDISESEAVESGFDSRIKNYR---------------------ILEGMGVTFHCKM 1268 Query: 1369 FGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 G P P++ W+K+ + I+ E + + Q S+ I V ED G Y+ N G Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325 Score = 40.4 bits (93), Expect = 0.013 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 11/109 (10%) Query: 159 RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE-SNYGVHTLEIN 217 R++++ + E M V + G+P P + WYKDG I +Y+++ G +L I Sbjct: 1250 RIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE---RYQMDFLQDGRASLRIP 1306 Query: 218 RADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +D Y+A A+N G + + V EP +G P +P Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYV-------EPAAPLGAPTYIP 1348 Score = 40.4 bits (93), Expect = 0.013 Identities = 21/71 (29%), Positives = 32/71 (45%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ +G + V G PDPE W+KN I+ S+ + + I+ VT+EDS Sbjct: 2042 TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2101 Query: 1415 KYSINIKNKYG 1425 + N G Sbjct: 2102 SIMVKAINIAG 2112 Score = 40.4 bits (93), Expect = 0.013 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 18/121 (14%) Query: 1332 QFKAAAFAEKNRG--RLIG--------------GLP-DVVTIMEGKTLNLTCTVFGNPDP 1374 QF+ A+ EK + R++G LP + +I G+ L + V G P P Sbjct: 17977 QFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRP 18036 Query: 1375 EVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 + W K+ + ++ + +V+ E A + IK +D GKY++ N G +++V Sbjct: 18037 NISWVKDGEPLKQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 18095 Query: 1435 V 1435 V Sbjct: 18096 V 18096 Score = 40.0 bits (92), Expect = 0.017 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + ++EG+ L++ P P V W K+ ++++ S+ ++K + K V + D+ Sbjct: 8091 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DA 8149 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y+I ++NK G + V V Sbjct: 8150 GIYTITLENKLGSATASINVKV 8171 Score = 40.0 bits (92), Expect = 0.017 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1344 GRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY-VS 1402 G L L + + G T+ L V G P P++ W K ++ L + + ++ + Sbjct: 13388 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSK--PNVNLRDRIGLDIKSTDFDTF 13445 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 + + V D+GKY + ++N G ++ + V V Sbjct: 13446 LRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478 Score = 40.0 bits (92), Expect = 0.017 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ + + G P P V W K+++++ +S++ + + +TI VT D+GKY + Sbjct: 20981 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKYIL 21039 Query: 1419 NIKNKYGGEKIDVTVSV 1435 I+N G K TVSV Sbjct: 21040 TIENGVGEPK-SSTVSV 21055 Score = 39.7 bits (91), Expect = 0.022 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 27/191 (14%) Query: 1263 NWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQA 1322 +W A + S ++ GGS+ ++ K++GK +E GKD R L Sbjct: 10126 DWTKSSADLEWSPPLKDGGSKVTGYIV----EYKEEGKEEWE--KGKDKEVRGTKLVVTG 10179 Query: 1323 FDE-AFAEFQ--QFKAAAFAEKN--------RGRLIG-------GLPDVVTIMEGKTLNL 1364 E AF +F+ A E + RL+ + D + + G + + Sbjct: 10180 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRI 10239 Query: 1365 TCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKY 1424 V G P P V W N++ L + +++ A SM IK G YS+ KN+ Sbjct: 10240 IAYVSGKPPPTVTWNMNER--TLPQEATIET-TAISSSMVIKNCQRSHQGVYSLLAKNEA 10296 Query: 1425 GGEKIDVTVSV 1435 G K + V V Sbjct: 10297 GERKKTIIVDV 10307 Score = 39.3 bits (90), Expect = 0.028 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + +G + LT + G P P W K QDI S+ + + + + IK DS Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSET-HTELVIKEADRGDS 23897 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y + ++NK G + + + V V Sbjct: 23898 GTYDLVLENKCGKKAVYIKVRV 23919 Score = 39.3 bits (90), Expect = 0.028 Identities = 60/321 (18%), Positives = 118/321 (36%), Gaps = 50/321 (15%) Query: 68 CRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKL- 126 C++ K + ++ E Q+ ++ S + +A Q +S+ A E++ ++ +++++KL Sbjct: 26632 CKLTIKAI--KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLA 26689 Query: 127 -----DKYAIQQMMEDKLAW--ERHTFEERISRAPEILVRLRSHTVWERMSV-------- 171 K I + ++ A E+ E I++ + +R+H + S Sbjct: 26690 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQ 26749 Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 +L V+W +G + + E YR + TL I +A D + ++ Sbjct: 26750 RLVLKANIAGATDVKWVLNGVELTNSEE---YRYGVSGSDQTLTIKQASHRDEGILTCIS 26806 Query: 232 TNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRRE 291 G V + + + D F I P S I E Sbjct: 26807 KTKEGIVKCQYDLTLSKELSDAPAF------ISQPRSQNI------------------NE 26842 Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 G+ V C + P P EW+++++ + S + SL + D G Sbjct: 26843 GQNVLFTCEISGEPS-----PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26897 Query: 352 LYTLRIVSRGGVSDHSAFLFV 372 YT++ + G +A L V Sbjct: 26898 KYTIKAKNFRGQCSATASLMV 26918 Score = 38.9 bits (89), Expect = 0.037 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK---YVSMTIKGVTS 1410 + + G + + G P PE+ W + + + F+ KV+ K Y ++I Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGE------FTDKVQIEKGVNYTQLSIDNCDR 17782 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 D+GKY + ++N G + VTV V + PPQ K Sbjct: 17783 NDAGKYILKLENSSGSKSAFVTVKV------LDTPGPPQNLAVK 17820 Score = 38.5 bits (88), Expect = 0.048 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ G ++L G P P + W K+ ++ SE + K ++++IK E Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK-ITLSIKNAKKEHG 21326 Query: 1414 GKYSINIKNKYGGEKIDVTV 1433 GKY++ + N + +TV Sbjct: 21327 GKYTVILDNAVCRIAVPITV 21346 Score = 38.5 bits (88), Expect = 0.048 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-DSGKYS 1417 G TL L G P P + WF + +Q SE+ +++ Y + +K V + +GKY Sbjct: 24338 GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE-NTEHYTHLVMKNVQRKTHAGKYK 24396 Query: 1418 INIKNKYG 1425 + + N +G Sbjct: 24397 VQLSNVFG 24404 Score = 38.1 bits (87), Expect = 0.063 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 K +Q P QW+K G I E K I S+ + +LEI R D Y+ A Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIY---ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4603 Query: 232 TNAHGQVSTNAAVVV 246 +N +G VS A + V Sbjct: 4604 SNEYGSVSCTATLTV 4618 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQL-SEHFSVKVEQAK----YVSMTIK 1406 D + + G+ +++ V G P P++ W KN+ I+ ++ + E+ ++I Sbjct: 9101 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9160 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSVY 1436 ED G Y++ N+ G +V V VY Sbjct: 9161 KAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D V + G+ L V G P P + W K+ ++++ + +K+ ++ K T Sbjct: 15164 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS-TNLVNKDSTRR 15222 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y++ N G K V V Sbjct: 15223 DSGAYTLTATNPGGFAKHIFNVKV 15246 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSEDS 1413 T++ G+ L + G P P V W K+ ++ L + V E + S +TIK ED Sbjct: 15853 TVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKDACREDV 15910 Query: 1414 GKYSINIKNKYG 1425 G Y + + N G Sbjct: 15911 GHYVVKLTNSAG 15922 Score = 37.0 bits (84), Expect = 0.14 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V + G + L V G P P+V W K D + + V+ + + I T +D Sbjct: 12310 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF--LVIPNSTRDD 12367 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDM 1445 SGKYS+ + N G + + V V V + D+ Sbjct: 12368 SGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12400 Score = 37.0 bits (84), Expect = 0.14 Identities = 16/79 (20%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 ++ G+ L + + G P P + W K+ ++ + +V + +++IK +D G Sbjct: 16935 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGG 16993 Query: 1415 KYSINIKNKYGGEKIDVTV 1433 +Y I + N G + + + Sbjct: 16994 QYGITVANVVGQKTASIEI 17012 Score = 37.0 bits (84), Expect = 0.14 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 907 VEARPGTKEISAGVDEQGNIYLGFDC--QEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 +E P + +I V E+G ++ + C + ++Q TW ++ + E+++I Sbjct: 25260 IEIGPVSGQIMHAVGEEGG-HVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV 25318 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSF 994 + LY+K+ K D GTY V + G SS+ Sbjct: 25319 AILYVKDITKLDDGTYRCKVVNDYGEDSSY 25348 Score = 36.6 bits (83), Expect = 0.18 Identities = 110/564 (19%), Positives = 213/564 (37%), Gaps = 96/564 (17%) Query: 879 QGKTYVFRVRAVNANGVGKP-------SDTSEPVLVEARP--GTKEISAGVDEQGNIYLG 929 +GKT+ ++ V + + + S T++ ++EA P K E+ I L Sbjct: 5319 EGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITL- 5377 Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 C+ D W K EEI ++ I+ G L +K D +D G Y V TD Sbjct: 5378 -KCEVSKDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY-VCDCGTDK 5434 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 ++ ++ RL+ + + + + +EI E PD ++ Sbjct: 5435 TKANVTVEA----RLIKVEKPLYGVEVFVGETAHFEI------------ELSEPDVHGQW 5478 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + + ++ S I D I+ ++ + G + Q + K+ + + + Sbjct: 5479 KLKGQPLTASPDCEIIEDGKKHIL--ILHNCQLGMTGEVSFQAANAKSAANLKVKELPLI 5536 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVL 1169 F T L + + V E+ E + C+V+ K F+WLK Sbjct: 5537 FITPLSDVK---------------------VFEKDEAKFECEVSREPK--TFRWLKG--- 5570 Query: 1170 YETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS--ILEIAGKVYDDMILAM 1227 T+ + +R EL+ KD ++ +K +D + + E K + L + Sbjct: 5571 --TQEITGDDR--FELI------KDGTKHSMVIKSAAFEDEAKYMFEAEDK-HTSGKLII 5619 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAW 1287 + K +PLK + E ++ D ++V W D ++ ++ + + Sbjct: 5620 EGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSM-------- 5671 Query: 1288 LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLI 1347 +D+GK F KD S+D + Q EA + K + Sbjct: 5672 --------QDEGKTHSITF--KD---LSIDDTSQIRVEAMGMSSEAKLTVL--EGDPYFT 5716 Query: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 G L D + + + + L C + D V WFK+ ++I+ S++ +K + K + + +K Sbjct: 5717 GKLQDYTGVEKDEVI-LQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADGKKRM-LILKK 5773 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDV 1431 D G+Y+ + K+D+ Sbjct: 5774 ALKSDIGQYTCDCGTDKTSGKLDI 5797 Score = 36.6 bits (83), Expect = 0.18 Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 24/144 (16%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 +W+++ I ++ KY I V+TL I A DD A Y+ TN G+ +AA + Sbjct: 6366 KWFRNEEAIFDSS---KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANL 6422 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF--RREGETVTLKCTM-- 301 + +EE R V PL D++ +EK VTF + VTLK T Sbjct: 6423 I----VEEEDLRIVE-----PLK--------DIETMEKKSVTFWCKVNRLNVTLKWTKNG 6465 Query: 302 LVTPDLKRVQPRAEWYRDDVLLKE 325 P RV R + Y+ + +K+ Sbjct: 6466 EEVPFDNRVSYRVDKYKHMLTIKD 6489 Score = 36.6 bits (83), Expect = 0.18 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 1370 GNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEK 1428 G P V W K+ Q L E V V +K V S++IK + ED G Y + + N G Sbjct: 19115 GRPQATVNWRKDGQT--LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19172 Query: 1429 IDVTVSV 1435 + +T+ V Sbjct: 19173 VPITIIV 19179 Score = 36.6 bits (83), Expect = 0.18 Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK--YVSMTIKGVTSEDSGKYSINIK 1421 L C V G+P P V W++ ++I +++ ++++ K Y + I VT +D+ Y + Sbjct: 24642 LVCKVTGHPKPIVKWYRQGKEI-IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRAT 24700 Query: 1422 NKYG 1425 N+ G Sbjct: 24701 NQGG 24704 Score = 36.2 bits (82), Expect = 0.24 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V G + + V G P P V W K DQ ++ ++ + + + + I D Sbjct: 14769 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECVRSD 14827 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVY 1436 SG Y + +N G +T+ V+ Sbjct: 14828 SGPYPLTARNIVGEVGDVITIQVH 14851 Score = 36.2 bits (82), Expect = 0.24 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT G+ L+C + G P P++ W++ +++ S + + + + ++T+ ED Sbjct: 24237 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH-TLTVMTEEQEDE 24295 Query: 1414 GKYSINIKNKYG 1425 G Y+ N+ G Sbjct: 24296 GVYTCIATNEVG 24307 Score = 35.4 bits (80), Expect = 0.41 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP + + + E SV V G P P V W K G + YR + +Y Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-----YRYKVSYNKQ 1089 Query: 213 T----LEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 T L I+ DD Y+ V N HG+ S +A+++ Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1126 Score = 35.4 bits (80), Expect = 0.41 Identities = 46/222 (20%), Positives = 81/222 (36%), Gaps = 34/222 (15%) Query: 145 TFEERISRA--PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGK 202 T E ++ R P +++ S E + + V G P P W+ DG I K Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVN-DYTHK 1458 Query: 203 YRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP 262 I+ + G +L I A D+ ++ VA N G+ S + + V +P Sbjct: 1459 VVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKP------- 1510 Query: 263 IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL 322 F+EK +EG + +K P+ P W ++ + Sbjct: 1511 ----------------MFVEKLKNVNIKEGSRLEMKVRATGNPN-----PDIVWLKNSDI 1549 Query: 323 LKESKWTKMFF--GEGQASLSFSHLHKDDEGLYTLRIVSRGG 362 + K+ K+ +G+A+L D YT +++ G Sbjct: 1550 IVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1591 Score = 35.0 bits (79), Expect = 0.53 Identities = 55/234 (23%), Positives = 82/234 (35%), Gaps = 50/234 (21%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V+W+KDG+ I + KY I S V L IN+ DD A YS A Sbjct: 6099 VKWFKDGAEIKKGK---KYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR--------- 6146 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 S M+ + F + E +T+ L C + Sbjct: 6147 ----------------------TSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV--- 6181 Query: 305 PDLKRVQPRAE--WYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR-- 360 +P AE WY+ D + E+ ++ + L + H +D G Y R+ S Sbjct: 6182 -----SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRT 6236 Query: 361 -GGVSDHS-AFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 G V H A F+ L G + C +++ V WK + T ES Sbjct: 6237 DGKVKVHELAAEFISKPQNLEI-LEGEKAEFVC-SISKESFPVQWKRDDKTLES 6288 Score = 34.7 bits (78), Expect = 0.69 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 175 FTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESN-YGVHTLEINRADFDDTATYSAVATN 233 +TV G P P V W+K+ +C + Y I N G T +N +D+ Y A N Sbjct: 3788 YTVVGEPAPTVTWFKENKQLCTSV---YYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3844 Query: 234 AHGQVSTNAAVVV 246 G+ + A ++V Sbjct: 3845 MLGESTCAAELLV 3857 Score = 33.9 bits (76), Expect = 1.2 Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 1367 TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 TV G P P V WFK ++ + S ++++ + + EDSG Y +N G Sbjct: 3789 TVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3847 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 R + L + VT+++G+ L L+C + N + +V+W K+ + + V ++T Sbjct: 4908 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4965 Query: 1405 IKGVTSEDSGKYSINIKN 1422 I D+G Y++ ++N Sbjct: 4966 INDADDTDAGTYTVTVEN 4983 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKY-RIESNYGVH 212 P I+ L+ E + V G V + KD + +P ++ R+ + Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI-----KPSRFFRMTQFEDTY 3353 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNA 242 LEI A +D TY+ VA+NA GQVS+ A Sbjct: 3354 QLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3383 Score = 33.1 bits (74), Expect = 2.0 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 3/93 (3%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + TV +K+ G PTP V W+KD + Q E+N Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN---SL 15899 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVV 246 L I A +D Y TN+ G+ V+V Sbjct: 15900 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 28/108 (25%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQ--------------------DIQLSEHFSVKV 1395 + G + L ++ G+P P + W K++ ++Q E F + + Sbjct: 8386 VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPL 8445 Query: 1396 EQAKYVSMTIKGVTS--------EDSGKYSINIKNKYGGEKIDVTVSV 1435 Q + + KG + D G Y I ++N +G K TVSV Sbjct: 8446 TQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK-------NDQDIQLSEHFSVKVEQAKYVS 1402 L + + + EG +N+ + G P P + WFK N + + H + K+ + Sbjct: 9817 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9875 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 + I D+G Y+I N G ++ ++V G P + P Sbjct: 9876 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL--GRPGPPVGP 9918 Score = 32.0 bits (71), Expect = 4.5 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G ++ + + G P PEV W K+ +I L +++ ++ + + I D+ Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTES-FTLLIIPECNRYDT 14537 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 GK+ + I+N G + V V V + ++ P K Sbjct: 14538 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK 14576 Score = 32.0 bits (71), Expect = 4.5 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 1364 LTCTVFGNP--DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIK 1421 LTC V + EV W+K+ + ++ + HF + I +T D G+Y I Sbjct: 26430 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 26489 Query: 1422 NKYGGEKIDV 1431 + G K ++ Sbjct: 26490 GEGGTSKTNL 26499 >gi|110349713 titin isoform novex-1 [Homo sapiens] Length = 27051 Score = 269 bits (688), Expect = 1e-71 Identities = 229/865 (26%), Positives = 373/865 (43%), Gaps = 101/865 (11%) Query: 153 APEILVRLR---SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 APEI + ++ TV ++L TV G P P + W K ++ Q + IE+ Sbjct: 7315 APEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK---RITIENVP 7371 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 T+ I + DT TY A N G+ + V V L Sbjct: 7372 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV--------------------LDK 7411 Query: 270 MIPYTHFDVQFL--EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK 327 P FD+ + E +T+ + K T V +R W++ +K++ Sbjct: 7412 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE--RRATDSEVWHKLSSTVKDTN 7469 Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAP 383 + + L + E ++ + + GV + A P+ P Sbjct: 7470 FKA------------TKLIPNKEYIFRVAAENMYGVGEPV------QASPITAKYQFDPP 7511 Query: 384 GAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYP 443 G P L+ D +D V +TW P+ SP+ GY+V+R + T+ WV+CN PVK Y Sbjct: 7512 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYR 7571 Query: 444 VTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD 503 V GL + Y FRV A N AG +PS+ ++ + DP+D Sbjct: 7572 VKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID--------------------- 7610 Query: 504 LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVGSGSWQRVNAQ 562 P PP ++ + V L+W P G + Y IE G+ W RV Sbjct: 7611 ------PPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV--A 7662 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 V + ++ + LMEG+ Y FRV + N+ G SEPSE + P+ ++ PS P + Sbjct: 7663 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7722 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 TK + ++W P+ + + Y V+ W+ + + + V LT G Y Sbjct: 7723 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVD-TTVKDTKCTVTPLTEGSLY 7781 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 +FRV A NA+G S+ ++ D + + T P PY + +++ + L W+ PK GG Sbjct: 7782 VFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGR 7841 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PI Y ++K+E W + + V + EG+ +F++ A N AG+G PS+P+ Sbjct: 7842 PIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT 7901 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 E E T P P P DL + + + WK P +G SP+ GY V+ +W+ Sbjct: 7902 EILSIEDPTSP-PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWM 7960 Query: 861 TVNQTTTANRYLKVSD-LQQGKTYVFRVRAVNANGVGKPSDTSEPVLV---EARP----G 912 VN + KV + + K YV RVRAVNA GV +PS+ SE V+ + +P Sbjct: 7961 RVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE 8020 Query: 913 TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 T +I E+ +I + F + S W K +E+ +R ++ DH +L+ P Sbjct: 8021 THDIIVIEGEKLSIPVPFRAVPVPTVS---WHKDGKEVKASDRLTMK--NDHISAHLEVP 8075 Query: 973 D--KEDLGTYSVSVSDTDGVSSSFV 995 + D G Y++++ + G +++ + Sbjct: 8076 KSVRADAGIYTITLENKLGSATASI 8100 Score = 268 bits (685), Expect = 3e-71 Identities = 209/769 (27%), Positives = 337/769 (43%), Gaps = 83/769 (10%) Query: 272 PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM 331 P DV+ L V + G + L T+ P+ P+ W + D++LK+ K + Sbjct: 7316 PEIFLDVKLLAGLTV---KAGTKIELPATVTGKPE-----PKITWTKADMILKQDKRITI 7367 Query: 332 FFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 +++++ + D G Y + V+ G + + V D PG P Sbjct: 7368 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK-------PGPPAAFDI 7420 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 D + ++TW PP S + Y V+R + W + + + VK + T L + Sbjct: 7421 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNK 7479 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 YIFRV A N G+ P + S A YQ D P Sbjct: 7480 EYIFRVAAENMYGVGEPVQASPITAK----------------------YQFD------PP 7511 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 GPPT + S+I+++ V L+W P G P+ Y++E+ + W R N + V+ Y Sbjct: 7512 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN-KMPVKDTTY 7570 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L K Y FRVL+ N G +PS+ T PI +D P PG+ KTSV + Sbjct: 7571 RVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRL 7630 Query: 631 QWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 W +P+H+ + Y ++ GT+ W + + + ++ GL G++Y FRV+AVN Sbjct: 7631 NWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVN 7689 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G SE S+ SD + + L PS P + ++N ++ L W VP+ GGSPI Y ++ Sbjct: 7690 KAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE 7749 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+V K W V+++ K T TV LTEGSLY F++AA N G + ++ + + Sbjct: 7750 KRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD- 7807 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 T PGP Y L +V + + W+ P G P+ Y ++ +E W+ +T Sbjct: 7808 TFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGP 7867 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNI 926 + +V+D+ +G F+VRA N GVG PS+ +E + +E P + + V + G Sbjct: 7868 DCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRK 7927 Query: 927 YLGFDCQ---------------EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 ++ + EM W + D +FK+E Sbjct: 7928 HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG--------VV 7979 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 PDKE Y + V + + V +P E+ + + PTI L++ Sbjct: 7980 PDKE----YVLRVRAVNAIG---VSEPSEISENVVAKDPDCKPTIDLET 8021 Score = 231 bits (588), Expect = 5e-60 Identities = 228/871 (26%), Positives = 358/871 (41%), Gaps = 147/871 (16%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 TV +V L TV G P P V W KDG+L+ + AE K ++ N + TLE+ + D Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLL-KPAEGIKMAMQRN--LCTLELFSVNRKD 12990 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y+ A N+ G S + V ++P G P + ++ M + ++ Sbjct: 12991 SGDYTITAENSSGSKSATIKLKVL-----DKP----GPPASVKINKM---------YSDR 13032 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 +++ E + T + + +P W ++ S S Sbjct: 13033 AMLSWEPPLEDGGSEITNYIVDKRETSRPN--------------WAQVSATVPITSCSVE 13078 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA------DPLVTGAPGAPMDLQCHDANRD 397 L + E + + ++ GV D +F A DP PG + +D Sbjct: 13079 KLIEGHEYQFRICAENKYGVGDP---VFTEPAIAKNPYDP-----PGRCDPPVISNITKD 13130 Query: 398 YVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRV 457 ++ V+WKPP SP+ GY +++ E NW + N P+ TGL EG Y FRV Sbjct: 13131 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13190 Query: 458 RAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGV 517 A+N AG +PS S A A DP PGPP Sbjct: 13191 TAINKAGPGKPSDASKAAYARDP---------------------------QYPPGPPAFP 13223 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM 576 + +R+ V LSW P G P++ Y +E S +W R N ++ R+ V LM Sbjct: 13224 KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLM 13283 Query: 577 EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV------- 629 E Y FRV + N+ G S+PS++ +D+ + P L + KT ++ Sbjct: 13284 EDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGE---LDADLRKTLILRAGVTMR 13340 Query: 630 ------------VQWDRPK-HEEDLLGYYVDCCVAGTNL-WEPCNHKPIGYNRFVVHGLT 675 + W +P + D +G + T L E N G Sbjct: 13341 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG---------- 13390 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +YI ++ N+ G E + V+KV L P P +T+ S + W+ P Sbjct: 13391 ---KYILTLE--NSCGKKEYTI---VVKV---LDTPGPPVNVTVKEISKDSAYVTWEPPI 13439 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGSPI+ Y + KR+ K+W V + SK T V L EG Y F++ A N GIG+ Sbjct: 13440 IDGGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGD 13498 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + K PGP DL V +S + WK P G S + GY VDF E+ Sbjct: 13499 PGETRDAVKAS----QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEE 13554 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKE 915 +W V ++ + K DL +GK Y FRV A N NG G PS+ + V AR Sbjct: 13555 -NKWQRVMKSLSLQYSAK--DLTEGKEYTFRVSAENENGEGTPSE----ITVVARDDV-- 13605 Query: 916 ISAGVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDH 964 ++ +D +G L + +E ++ A +W K + ++ D R +E+ + Sbjct: 13606 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13665 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + L + + K D G Y++++ + G + Sbjct: 13666 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13696 Score = 226 bits (575), Expect = 2e-58 Identities = 233/937 (24%), Positives = 390/937 (41%), Gaps = 106/937 (11%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E++S+ + F + P P V W+KDG + + +++++ LE+ ++ D Sbjct: 8030 EKLSIPVPF--RAVPVPTVSWHKDGK---EVKASDRLTMKNDHISAHLEVPKSVRADAGI 8084 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGV 286 Y+ N G + + V V IGLP P + K Sbjct: 8085 YTITLENKLGSATASINVKV----------------IGLPG----PCKDIKASDITKSSC 8124 Query: 287 TFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLH 346 E TP L V R E R + + GE + S + L Sbjct: 8125 KLTWEPPEFDGG-----TPILHYVLERREAGR-------RTYIPVMSGENKLSWTVKDLI 8172 Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANRDYVIVT 402 + E + ++ V++ G + ++ +P++ P P+D++ H+ + + +T Sbjct: 8173 PNGEYFFRVKAVNKVGGGE-----YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8227 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 WKPP S +MGY +++ G W +CN+ V I Y GL EG+ Y FRVRA N+ Sbjct: 8228 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8287 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPP----TGVH 518 AGIS PSR + A+DP+D + V L E+ D++ DA + G P T + Sbjct: 8288 AGISEPSRATPPTKAVDPIDAPK---VILRTSLEVK-RGDEIALDASISGSPYPTITWIK 8343 Query: 519 ASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSP-RYAVFDLME 577 + + P R + + E V+ QR++ + + + V D + Sbjct: 8344 DENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT--QRLSIDNSKKGESQLRVRDSLR 8401 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 ++ + N HG+++ S + P P + KTSV+ +W+ P Sbjct: 8402 PDHGLYMIKVENDHGIAKAPCTVSVLDT------PGPPINFVFEDIRKTSVLCKWEPPLD 8455 Query: 638 E--EDLLGYYVDCCVAGTNLWEPCNH-----KPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + +++ Y ++ + +P + + + ++ V L G++Y+FRV+A N Sbjct: 8456 DGGSEIINYTLE----KKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8511 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKR 750 G ++ + P P + + +SM + W PK GSPILGY+L+KR Sbjct: 8512 GPGPPCVSKPLV-AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKR 8569 Query: 751 EVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTM 810 EV+ +W VN S VDGL EG Y F++ A N AG G+ S PS+ K + Sbjct: 8570 EVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP-KTAHDPI 8628 Query: 811 PEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR 870 PGP + T++ + W+ P ++G + GYFVD + EW + R Sbjct: 8629 SPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVR 8687 Query: 871 YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 V ++++G Y RV AVNA G G P +T +PV V + V +G I + Sbjct: 8688 QYTVKEIREGADYKLRVSAVNAAGEGPPGET-QPVTVAEPQEPPAVELDVSVKGGIQIMA 8746 Query: 931 DCQEMTDA-------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 A W K E+ D +R I+ VG S+L +K+ ++D G Y ++ Sbjct: 8747 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8805 Query: 984 VSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 +++ G S F E+ ++ P + LK + K + W E Sbjct: 8806 ATNSCG--SKFAAARVEV-------FDVPGPVLDLKPVVTNR---KMCLLNWSDPEDDGG 8853 Query: 1044 DASYRFIINDREV------SDSEIHRIKCDKATGIIE 1074 FII ++ E R KCD TG++E Sbjct: 8854 SEITGFIIERKDAKMHTWRQPIETERSKCD-ITGLLE 8889 Score = 218 bits (554), Expect = 4e-56 Identities = 194/813 (23%), Positives = 330/813 (40%), Gaps = 104/813 (12%) Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPM 387 WT + SL + L + +E ++ + V++ GV + V +P V PG P Sbjct: 17394 WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVL--PGPPK 17451 Query: 388 DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGL 447 L+ + +D + V W P++ S ++GY V++ + W++CN + + VTGL Sbjct: 17452 SLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGL 17511 Query: 448 FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD 507 E Y FRV A N+AG+ PS + A DP+ Sbjct: 17512 TEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFK------------------------ 17547 Query: 508 AQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566 PGPPT H + ++N + L+W P G + L Y +E WQ V QT +R Sbjct: 17548 ---PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLR 17604 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD----------------VTV 610 R+ + L E + Y RV + N+ GL E + + ++ +D + V Sbjct: 17605 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 17664 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 R+ + + + W R + G + D K + Y + Sbjct: 17665 RAGGSARIHIPFKGRPTPEITWSREE------GEFTDKVQI---------EKGVNYTQLS 17709 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 + + + +K N+ G +S + V+ L P P + + S L Sbjct: 17710 IDNCDRNDAGKYILKLENSSG-----SKSAFVTVKV-LDTPGPPQNLAVKEVRKDSAFLV 17763 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W+ P GG+ + Y +DKRE K + V+S SK T V+ LTEG++Y F++ A N Sbjct: 17764 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAENE 17822 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 G+G P + + K P P +T +V TS ++W+ P + G S V GY V+ Sbjct: 17823 FGVGVPVETVDAVKAAE----PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17878 Query: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE-- 908 + + +W V ++ N V+ L G+ Y FRV+A N G P PV+ + Sbjct: 17879 MQPKGTEKWSIVAESKVCNAV--VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17936 Query: 909 -ARPGTK------EISAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 +P K I AG D + I +G +W K E + R +E Sbjct: 17937 TIQPSLKLPFNTYSIQAGEDLKIEIPVIG------RPRPNISWVKDGEPLKQTTRVNVEE 17990 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTI-PLK 1019 + L++K +K+D G Y+V+ +++ G ++ E L + E P + P++ Sbjct: 17991 TATSTVLHIKEGNKDDFGKYTVTATNSAGTAT---------ENLSVIVLEKPGPPVGPVR 18041 Query: 1020 SELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDR 1079 + E+ V W + +I+ R+ + + H + A I++ + Sbjct: 18042 FD---EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 18098 Query: 1080 FSIENEGTYTVQIHDGK-AKSQSSLVLIGDAFK 1111 E + + GK A S V++ FK Sbjct: 18099 TGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 18131 Score = 216 bits (551), Expect = 1e-55 Identities = 213/874 (24%), Positives = 350/874 (40%), Gaps = 152/874 (17%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 T+ S++L +V G P PV+ W K G + A I++ L +++ + D Sbjct: 23085 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-----IDTTESYSLLIVDKVNRYD 23139 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGD-------EEPFRSVGLPIGLP-LSSMIPYTH 275 Y+ A N G+ S V V G E SV + +P + P + Sbjct: 23140 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23199 Query: 276 FDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE 335 + V+ E F+ TVT KC+ + V+ ++R +L E+ +G Sbjct: 23200 YIVEKREAAMRAFK----TVTTKCSKTLYRISGLVEGTMYYFR---VLPEN-----IYGI 23247 Query: 336 GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDAN 395 G+ + + LV+ P P L+ D Sbjct: 23248 GEPCETSDAV--------------------------------LVSEVPLVPAKLEVVDVT 23275 Query: 396 RDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIF 455 + V + W+ P S + GY ++ C+ GT W++ + ++ VT L EG Y+F Sbjct: 23276 KSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLF 23335 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP-GPP 514 R+RA N G+S P + V A+ DLR L + L + I+ VP G P Sbjct: 23336 RIRAQNEKGVSEPR---ETVTAVTVQDLRVLPTIDLSTMPQKTIH---------VPAGRP 23383 Query: 515 TGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 + R SW +F + S +RV +T + + + + Sbjct: 23384 VELVIPIAGRPPPAASW------------FFAGSKLRES---ERVTVETHTKVAKLTIRE 23428 Query: 575 LMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 + + + N G L +P T PI+ ++ Sbjct: 23429 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA-------------- 23474 Query: 625 KTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIF 682 TS+ + W+ P+ + L GY V+ A W P + + + F LT G +Y+F Sbjct: 23475 -TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVF 23532 Query: 683 RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 RV A N G+ Q S+VI+ ++++ +P P + + + MTL W P+ GGS + Sbjct: 23533 RVAATNRFGIGSYLQ-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23591 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 GY ++++EV W VN P T GLTEG YE ++ A+N G G+PS PS+ Sbjct: 23592 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23651 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P PG + + TS+ + W P G S V+GY ++ ++ D EW Sbjct: 23652 IVAMDPIAP-PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKC 23710 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 N T T R ++ L QG Y FRV A NA G G+P++ PGT +++ ++ Sbjct: 23711 NTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLE- 23760 Query: 923 QGNIYLGFDCQEMTDASQFT---------------------WCKSYEEISDDERFKIETV 961 Y ++ E F W K ++IS +R I T Sbjct: 23761 ----YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATS 23814 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 H++L +K D+ D GTY + + + G + ++ Sbjct: 23815 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23848 Score = 216 bits (549), Expect = 2e-55 Identities = 172/613 (28%), Positives = 259/613 (42%), Gaps = 54/613 (8%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 ++ P +P A W D +L+ KM A L S + D+G+YTL++ +R Sbjct: 7042 ILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR- 7100 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 V S + D V P AP +L+ D +D V +TW+PP+ SP+ GY V++ Sbjct: 7101 -VKTISG-----EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEK 7154 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 EV W + D V ++ V L +G+ Y+F+V A N G P+ V + V P Sbjct: 7155 REVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTP- 7212 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 A VP PP V + + N + L+W+PP G Sbjct: 7213 --------------------------ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSR 7246 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ GS W V V + V L EGK Y +RV + NR G S+PS T Sbjct: 7247 IKGYIVERCPRGSDKW--VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7304 Query: 601 SPIQAQDVTVVPS--APGRVLASRNTKTSVVVQWDRP---KHEEDLLGYYVDCCVAGTNL 655 IQA D P ++LA K ++ K E + D + Sbjct: 7305 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7364 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY 715 N V + YI ++AVN G + E +V L P P Sbjct: 7365 ITIENVPKKSTVTIVDSKRSDTGTYI--IEAVNVCGRATAVVEVNV------LDKPGPPA 7416 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL 775 + + S L W P+ GGS I Y +++R + WH++ SS K T L Sbjct: 7417 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL-SSTVKDTNFKATKL 7475 Query: 776 TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKA 835 Y F++AA N+ G+GEP S + PGP L ++ ++ + W Sbjct: 7476 IPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTLTWCE 7533 Query: 836 PVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 P G SP++GY+V+ + D +W+ N+ + +V L K Y FRV A N G Sbjct: 7534 PDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGP 7593 Query: 896 GKPSDTSEPVLVE 908 GKPS ++EP+L++ Sbjct: 7594 GKPSKSTEPILIK 7606 Score = 207 bits (526), Expect = 8e-53 Identities = 199/842 (23%), Positives = 329/842 (39%), Gaps = 127/842 (15%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 ++G P P V W KDG + + A + I+S TL + D Y +N G Sbjct: 18359 IRGKPIPDVVWSKDGKELEETA--ARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18416 Query: 237 QVSTNAAVVVRRFRGDEE-PFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETV 295 S V V G E P + G+ Sbjct: 18417 TKSIPITVKVLDRPGPPEGPLKVTGV---------------------------------T 18443 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKES----KWTKMFFGEGQASLSFSHLHKDDEG 351 KC + P L+ Y ++ K WT++ + + L +E Sbjct: 18444 AEKCYLAWNPPLQDGGANISHY---IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEY 18500 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 ++ + V++ G+ + V +P PG P + +D ++VTW P Sbjct: 18501 IFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITKDSMVVTWARPVDDGG 18558 Query: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRV 471 + + GY +++ + W +CN + + VTGL EG SY FRV A N+AG+ PS Sbjct: 18559 TEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEP 18618 Query: 472 SDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW 531 S A D A+Y PGPP+ ++ SR+ V L+W Sbjct: 18619 SVFYRACD------------------ALYP---------PGPPSNPKVTDTSRSSVSLAW 18651 Query: 532 EPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANR 590 P G P+ Y +E + W T ++ ++ V L E Y FR+ + N Sbjct: 18652 SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINS 18711 Query: 591 HGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTKTSVVVQWDR 634 G+ EP+ + + AQ+ V + SA R+ + + V+W++ Sbjct: 18712 EGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK 18771 Query: 635 PKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 E +L V + + V+ +T + + + N Sbjct: 18772 A---EGILTDRAQIEVTSS------------FTMLVIDNVTRFDSGRYNLTLEN------ 18810 Query: 695 NSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 NS L PS P +T+ S+TL W+ P GG+ I Y ++KRE Sbjct: 18811 NSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 18870 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 K + + ++ +K T ++ L EG Y F++ A N GIG P++ +E K +P PG Sbjct: 18871 KAYATITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLP-PG 18928 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 +T +V + + W+ P G S ++GY V+ + + + +W T Q T + Sbjct: 18929 ---RVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE--ATI 18983 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL---VEARPGTK----EISAGVDEQGNIY 927 S L G+ YVFRV AVN G P PV+ +E +P + + EQ I Sbjct: 18984 SGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKID 19043 Query: 928 LGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 + F + + W K + + + R + + + L +K KED+GTY + VS++ Sbjct: 19044 VPFKGRPQATVN---WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 19100 Query: 988 DG 989 G Sbjct: 19101 AG 19102 Score = 206 bits (525), Expect = 1e-52 Identities = 201/762 (26%), Positives = 307/762 (40%), Gaps = 95/762 (12%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + ++++ +K+ V G P P + W KDG + Q + +E Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT---RVNVEETATSTV 17996 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I + DD Y+ ATN+ G + N +V+V E+P G P+G + + Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVL-----EKP----GPPVG-----PVRF 18042 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 F V E T C + KR W+ + Sbjct: 18043 DEVSADF-----VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATV---------- 18087 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCH 392 + ++ + L E + + +R G S V P G PG P Sbjct: 18088 --ARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VT 18142 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 ++D ++V W P + ++GY +++ E + WV+ N P++ K+ TGL EG Sbjct: 18143 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 18202 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y F+V A N GI +PS+VS+ A DP D Sbjct: 18203 YEFKVSAENIVGIGKPSKVSECFVARDPCD------------------------------ 18232 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYA 571 PP A I+RN V L W+ P G + Y +EK + G W + + T V + Sbjct: 18233 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TNVLETEFT 18291 Query: 572 VFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L+E + Y FRV++ N G SEPS+ + I A+D AP L + VV Sbjct: 18292 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEI---DAPNASLDPKYKDVIVVH 18348 Query: 631 QWDRPKHEEDLLGYYVDCCV---AGTNLWEPCNH----KPIGYNRFVVHGL--TTGEQYI 681 + E D+ G + V G L E I VV T G QYI Sbjct: 18349 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGS 740 ++ V +S I V+ L P P G + + L W P GG+ Sbjct: 18409 LKLSNVGGT-------KSIPITVK-VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18460 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I Y ++KRE +W +V S+ + V L G+ Y F++ AVN GIGEP + Sbjct: 18461 NISHYIIEKRETSRLSWTQV-STEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESG 18519 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 C + PGP + S+V+ W PV G + + GY ++ R+++ W Sbjct: 18520 PVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18577 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 N+ T + L+V+ L +G +Y FRV A NA GVG+PS+ S Sbjct: 18578 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18619 Score = 206 bits (525), Expect = 1e-52 Identities = 205/865 (23%), Positives = 323/865 (37%), Gaps = 151/865 (17%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 S+++ VQG P P V W+KDG + + I G +L + A D Y+ Sbjct: 21603 SLRIKALVQGRPVPRVTWFKDG---VEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTV 21659 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEE-PFRSVGLP-------IGLPLSS-MIPYTHFDVQF 280 A NA G V V+ G P R + PL+ P TH+ ++ Sbjct: 21660 EAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEK 21719 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 E T R + KC +K + +R + K FG G+ Sbjct: 21720 RE----TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNK--------FGVGRPL- 21766 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANR 396 D+DP+V P AP + + Sbjct: 21767 ---------------------------------DSDPVVAQIQYTVPDAPGIPEPSNITG 21793 Query: 397 DYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQC-NDAPVKICKYPVTGLFEGRSYIF 455 + + +TW P + S + Y ++R E + WV+ + P+ ++ VTGL EG Y F Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 21853 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPT 515 V A N+AG+ S +S + +P++ PGPPT Sbjct: 21854 HVMAENAAGVGPASGISRLIKCREPVN---------------------------PPGPPT 21886 Query: 516 GVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 V ++ S+ V L W P G + + Y IE G W +VNA+ V++ RY V D Sbjct: 21887 VVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT-RYTVTD 21945 Query: 575 LMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS----------------APGRV 618 L G+ Y FRV + N G + E+T I+A D P A R+ Sbjct: 21946 LQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRL 22005 Query: 619 LASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 + + + W +P L T E CN G V + + Sbjct: 22006 FIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSK 22065 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 F VK L P P IT + S TL W P G Sbjct: 22066 SITFTVKV---------------------LDTPGPPGPITFKDVTRGSATLMWDAPLLDG 22104 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+ I Y ++KRE ++W ++ ++ I V+ L EG Y F+++AVN G+GEP + Sbjct: 22105 GARIHHYVVEKREASRRSWQVISEKCTRQ-IFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22163 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E +P P L + +S V+ W P + G S ++GY ++ R++ + Sbjct: 22164 MPEPIVATE----QPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22219 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W+ T V L + Y FRV+A N G +P + V+++ +I Sbjct: 22220 WVEAGHTKQLT--FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE----PQIEP 22273 Query: 919 GVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDHSKL 967 D G C+ + A + TW + + +R I T D + L Sbjct: 22274 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTL 22333 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSS 992 +K+ + D G Y +++ +T GV + Sbjct: 22334 TVKDSMRGDSGRYFLTLENTAGVKT 22358 Score = 206 bits (523), Expect = 2e-52 Identities = 163/604 (26%), Positives = 252/604 (41%), Gaps = 58/604 (9%) Query: 311 QPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 +P+ W++D+ + E T + +L + D G Y +V F Sbjct: 10475 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC--VVVENSTGSRKGFC 10532 Query: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 V D G P P+ + +DY++++WKPP S + Y +++ EVG + W+ Sbjct: 10533 QVNVVDR--PGPPVGPVSFD--EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 10588 Query: 431 QCNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAV 489 A K CK V+ L EG+ YIFR+ A N GIS P VSD++ A D Sbjct: 10589 PVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL-VSDSMKAKDRF-------- 10637 Query: 490 HLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKS 549 +VP P +E++++ +++W P GK Y +EK Sbjct: 10638 -------------------RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR 10678 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W RV ++ V DL+EG Y FRV + N G+ +PS + P+ A+D Sbjct: 10679 ETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI 10738 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 PS P A T SV + W P+H+ +LGY V+ G W NH P Sbjct: 10739 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 10798 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 ++ V GL G+ Y FRV AVNA G S+ + + + V+ L P + Sbjct: 10799 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10858 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 + ++ G P K + PT +D GS E + Sbjct: 10859 KVGDTLRLSAIIKGVPFPKVTWKKED------------RDAPTKARIDVTPVGSKLEIRN 10906 Query: 786 AAVNLAGI----GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 AA GI E S+ + + +PGP DL E+R S + WK P+ G Sbjct: 10907 AAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGG 10966 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y V+ R+ + +W ++ T+ + L +G Y+FRV A N G G +T Sbjct: 10967 SVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGPFVET 11025 Query: 902 SEPV 905 +P+ Sbjct: 11026 PKPI 11029 Score = 204 bits (520), Expect = 4e-52 Identities = 208/851 (24%), Positives = 344/851 (40%), Gaps = 108/851 (12%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLE------INRADFDDT 224 +++ ++G PTP W DG +A + G + I + + T E I T Sbjct: 9456 IRIPAVIKGRPTPKSSWEFDGKAK-KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9514 Query: 225 ATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF 284 YS A N GQ + N V V G + + + G Sbjct: 9515 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRG-------------------- 9554 Query: 285 GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSH 344 + L M PD + + + WTK+ G + Sbjct: 9555 ---------SCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPD 9602 Query: 345 LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTW 403 L + + + +R +R G+ + A DP+ P P+ L+ ++ V ++W Sbjct: 9603 LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYP--PDPPIKLKIGLITKNTVHLSW 9660 Query: 404 KPPNTTTESPVMGYFVDRCE---VGTNN--WVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 KPP SPV Y V+ GT W QCN V+ ++ V L EG Y FRV+ Sbjct: 9661 KPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVK 9720 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD--AQVPGPPTG 516 AVN+AG+S+PS A + P D +R KE ++ + A++ G P Sbjct: 9721 AVNAAGVSKPS------ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVP-- 9772 Query: 517 VHASEISRNYVVLSW---EPPTPRGKDPLMY--FIEKSVVGSGSWQRVNAQTAVRSPRYA 571 + L+W P P K+P++Y + K VV + + Y Sbjct: 9773 ---------FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT 9823 Query: 572 VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 + + + + N L P PI+ + V+ + + Sbjct: 9824 I-TAVNNLGTASKEMRLNV--LGRPGPPVGPIKFESVSA---------------DQMTLS 9865 Query: 632 WDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 W PK + + Y ++ A W + +P + + L G +Y+FR+ A N Sbjct: 9866 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNK 9924 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 G+ E +S+ + +VP P T+ + +SMT+ W+ P++ GGSP+ GY+L+ Sbjct: 9925 YGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM 9983 Query: 750 REVHHKNWHEVNSSPSKPTIL----TVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++ K W VN P K L V GL EGS Y+F++ A+N AG+G S PS+ Sbjct: 9984 KDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 10043 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P PGP + + +S + W P+ G S V+GY V+++EE EW Sbjct: 10044 RDPIAP-PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 10101 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--PGTKEISAGVDEQ 923 L V+ L++G Y FRVRAVN G+G+P + ++ + ++ R ++ A V ++ Sbjct: 10102 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDR 10161 Query: 924 GNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLG 978 ++ G + + S TW + E + + IET S + +KN + G Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10219 Query: 979 TYSVSVSDTDG 989 YS+ + G Sbjct: 10220 VYSLLAKNEAG 10230 Score = 203 bits (516), Expect = 1e-51 Identities = 211/854 (24%), Positives = 339/854 (39%), Gaps = 152/854 (17%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFD-----------DTA 225 V G P P ++W KDG + G LEI ADF D+ Sbjct: 15113 VSGRPPPTMEWSKDGKEL--------------EGTAKLEIKIADFSTNLVNKDSTRRDSG 15158 Query: 226 TYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFG 285 Y+ ATN G V V G E PL+ Sbjct: 15159 AYTLTATNPGGFAKHIFNVKVLDRPGPPEG----------PLA----------------- 15191 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK---WTKMFFGEGQASLSF 342 VT E + KC + P L + + Y V +E+ WT + L Sbjct: 15192 VT-----EVTSEKCVLSWFPPLDDGGAKIDHYI--VQKRETSRLAWTNVASEVQVTKLKV 15244 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + L K +E ++ + V++ GV + V +P G P P + + +D ++V Sbjct: 15245 TKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY--GPPDPPKNPEVTTITKDSMVVC 15302 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P++ S ++ Y V+R + W++CN + +Y V+GL EG Y FR+ A N+ Sbjct: 15303 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15362 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AGIS PS S A D +++ PGPP + Sbjct: 15363 AGISAPSPTSPFYKACD------------------TVFK---------PGPPGNPRVLDT 15395 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 SR+ + ++W P G + Y +E ++ WQ V +++ Y + L E + Y Sbjct: 15396 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15455 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTK 625 R+ + N GL EP+ + +A+D VT+ R+ + Sbjct: 15456 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 15515 Query: 626 TSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685 + V+W R H E L ++ + T L NRF +YI V+ Sbjct: 15516 PAPEVKWARD-HGESLDKASIESTSSYTLLIVG------NVNRF------DSGKYILTVE 15562 Query: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 + + +S + V+ L P P + + S+TL W P GGS I Y Sbjct: 15563 -------NSSGSKSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNY 15614 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++KRE K + V ++ K T VD L EG Y F++ A N GIG P++ +E K Sbjct: 15615 IVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 15673 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 +P PG +T +V S+ + W+ P + G S + GY V+ + + + +W T Sbjct: 15674 SERPLP-PGK---ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--A 15727 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---------GTKEI 916 T ++ L QG+ Y FRV A N G+ P S PV+ + T + Sbjct: 15728 TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV 15787 Query: 917 SAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKE 975 AG D + ++ ++G TW K + R E+ ++S L +K+ +E Sbjct: 15788 LAGEDLKVDVPFIG------RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15841 Query: 976 DLGTYSVSVSDTDG 989 D+G Y V ++++ G Sbjct: 15842 DVGHYVVKLTNSAG 15855 Score = 200 bits (508), Expect = 1e-50 Identities = 212/862 (24%), Positives = 330/862 (38%), Gaps = 118/862 (13%) Query: 165 VWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH----TLEINRAD 220 V E +V + ++G P P + W+K EP Y N V TL I ++ Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9815 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQF 280 DT Y+ A N G S + V G P+G P+ F+ Sbjct: 9816 RSDTGLYTITAVNNLGTASKEMRLNV---------LGRPGPPVG-PIK-------FESVS 9858 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 ++ +++ + K T V KR R W KE +T EG Sbjct: 9859 ADQMTLSWFPPKDDGGSKITNYVIE--KREANRKTWVHVSSEPKECTYTIPKLLEGHE-- 9914 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 Y RI+++ + + PGAP R+ + Sbjct: 9915 ------------YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMT 9962 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC----KYPVTGLFEGRSYIFR 456 V W+ P SPV GY+++ + + W + N P+K Y VTGL EG Y FR Sbjct: 9963 VNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 10022 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 V A+N+AG+ S SD A DP+ PGPP Sbjct: 10023 VYAINAAGVGPASLPSDPATARDPI---------------------------APPGPPFP 10055 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDL 575 ++ +++ L W PP G + Y +E G W++ VR + V L Sbjct: 10056 -KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GKDKEVRGTKLVVTGL 10113 Query: 576 MEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--------------APG--RVL 619 EG Y FRV + N G+ EP E+T I+ +D V P A G R++ Sbjct: 10114 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10173 Query: 620 ASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 A + K V W+ + ++ + + + C Q Sbjct: 10174 AYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS---------------HQ 10218 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 ++ + A N G + + DV+ V + P + +T +C L W P+ GG Sbjct: 10219 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCK-----LTWFSPEDDGG 10273 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPI Y ++KRE + W V + ++ TV GL +G Y F+IAA N G+G + Sbjct: 10274 SPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSIGMGPFVET 10332 Query: 800 SEHFKC-EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 SE E T+PE DL EV ++ + W P Y G S + Y ++ R + Sbjct: 10333 SEALVIREPITVPERPE--DLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10390 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 + V +R V L++G TY +RV AVN G GKPS ++P+ + + Sbjct: 10391 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10450 Query: 919 GVDEQGNIYLGFDCQEMTDA------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 ++ I +G + +T + +W K ++ +D+R I+T L Sbjct: 10451 DFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 10509 Query: 973 DKEDLGTYSVSVSDTDGVSSSF 994 + D G Y V V ++ G F Sbjct: 10510 KRSDSGKYCVVVENSTGSRKGF 10531 Score = 199 bits (506), Expect = 2e-50 Identities = 202/839 (24%), Positives = 329/839 (39%), Gaps = 101/839 (12%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +V+ ++G P P +W DGS I Y +E++ L I DT Y Sbjct: 11155 TVRFPAIIRGVPVPTAKWTTDGSEI---KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 +NA G + + V G P G P DV Sbjct: 11212 TVSNAAGSKTVAVHLTVLDVPGP---------PTG-------PINILDVT---------- 11245 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 E T++ + P P + + ++ W + G + L HL K Sbjct: 11246 PEHMTISWQ-----PPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11300 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAPGAPMDLQCHDANRDYVIVTWKP 405 E ++ +R ++ GV D+ P V P P D + V+W Sbjct: 11301 EYVFRVRAENKIGVGPPL------DSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTL 11354 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + SP+ GY+++R EV T WV+ N P+ K+ VTGL+EG +Y FRV A N AG+ Sbjct: 11355 PKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGL 11413 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 S+PS SD + A P+ + PGPP + SR Sbjct: 11414 SKPSPSSDPIKACRPI---------------------------KPPGPPINPKLKDKSRE 11446 Query: 526 YVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 L W P G P++ Y +E G+ W R+N +R + V L+EG Y FR Sbjct: 11447 TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFR 11506 Query: 585 VLSANRHGLSEPSEITSPIQAQDVTVVPSAP-----GRVLASRNTKTSVVVQWDRPKHEE 639 + +AN G EP E+ + A+D+ P V+ R +T ++ + + E Sbjct: 11507 IKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEP 11566 Query: 640 DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQES 699 D+ + + P + +YI ++A S ++Q S Sbjct: 11567 DITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI-----ISAKNSSGHAQGS 11621 Query: 700 DVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHE 759 ++ V L P + + N + T+ W+ P +GGS I + ++ R+ + K W Sbjct: 11622 AIVNV---LDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSI 11678 Query: 760 VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDL 819 V S +K I L + Y F++ A N G+G P+ ++ + PG +L Sbjct: 11679 VASDVTKRLIKA--NLLANNEYYFRVCAENKVGVG-PTIETKTPILAINPIDRPGEPENL 11735 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + T + + W+ P Y G SP Y V+ R + + +W V++ + + V + Sbjct: 11736 HIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVE 11795 Query: 880 GKTYVFRVRAVNANG---------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 + Y FRV+ N G V D +PVL G + AG + + G Sbjct: 11796 NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG--DTIRLEAGV 11853 Query: 931 DCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + + + +T K +++ R KI+T D SK L + D G Y V+ ++T G Sbjct: 11854 RGKPFPEVA-WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911 Score = 198 bits (503), Expect = 4e-50 Identities = 178/670 (26%), Positives = 280/670 (41%), Gaps = 68/670 (10%) Query: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313 EP S G PI + P DV+F + V + GE + + + P P Sbjct: 19398 EPSESTG-PIIVKDDVEPPRVMMDVKFRDVIVV---KAGEVLKINADIAGRP-----LPV 19448 Query: 314 AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W +D + ++E T++ + L+ + D G Y L + + G + V Sbjct: 19449 ISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 19508 Query: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433 D G P P+++ A + ++W P + + Y V++ E W C Sbjct: 19509 DK----PGPPAGPLEINGLTAEK--CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC- 19561 Query: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493 + +++ VT L +G YIFRV VN G+ P S A+ ALDP Sbjct: 19562 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKALDPF------------ 19608 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVG 552 VP PPT + + +++ + L W P G + Y IE+ Sbjct: 19609 ---------------TVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19653 Query: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612 S W RVN + V R L EG Y +RV + N GLS PSE + I+A+D +P Sbjct: 19654 SLRWVRVN-KKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19712 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 S P + + KT++ + W +P + + GY V+ + W+ G + Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19771 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVP----SHPYGITLLNCDGHS 726 + GLTTG +Y+FRVK+VN VG S+ S SD + P TL+ G S Sbjct: 19772 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19831 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 T+ VP G P+ K + + V+++ S+ T LT++ ++ + Sbjct: 19832 FTM--TVP--FRGRPVPNVLWSKPDTDLRTRAYVDTTDSR-TSLTIENANRNDSGKYTLT 19886 Query: 787 AVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSG 846 N+ + + PGP ++T +V S V+ W P G +PV Sbjct: 19887 IQNVLS-------AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKN 19939 Query: 847 YFVDFREEDAGEWITVNQTTTANRY-LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE W++V T NR KV++LQ+G Y FRV N GVG P++T E V Sbjct: 19940 YHIEKREASKKAWVSV--TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19997 Query: 906 LVEARPGTKE 915 + +P E Sbjct: 19998 KITEKPSPPE 20007 Score = 196 bits (497), Expect = 2e-49 Identities = 206/843 (24%), Positives = 341/843 (40%), Gaps = 125/843 (14%) Query: 170 SVKLCFTVQGFPTPVVQWYKD------GSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 SVKL + G P P ++WYKD +L+C +E+ + ++ I AD + Sbjct: 20517 SVKLRAGISGKPAPTIEWYKDDKELQTNALVC---------VENTTDLASILIKDADRLN 20567 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y NA G S V + G P G P+ F EK Sbjct: 20568 SGCYELKLRNAMGSASATIRVQILDKPG----------PPGGPIE-------FKTVTAEK 20610 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 + +R + K T + KR R W L+E ++ + Sbjct: 20611 ITLLWRPPADDGGAKITHYIVE--KRETSRVVWSMVSEHLEE------------CIITTT 20656 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-GAPGAPMDLQCHDANRDYVIVT 402 + K +E ++ +R V++ G+ + V + VT G PG P + ++ + V Sbjct: 20657 KIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKITKNSMTVV 20713 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P S + GYF+++ + + W + ++ + VTGL E Y +RV AVN+ Sbjct: 20714 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 20773 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AG S S+ A DP+D PGPP + ++ Sbjct: 20774 AGQGPFSEPSEFYKAADPID---------------------------PPGPPAKIRIADS 20806 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 +++ + L W P G + Y +E W V+ + VR+ Y V +L G +Y Sbjct: 20807 TKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNY 20866 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP------GRVLASRNTKTSVVVQWD-R 634 FRV + N G EP E+ P+QA+D+ P V+A V++ + R Sbjct: 20867 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGR 20926 Query: 635 P------KHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 P + +E LG + T+ + N TG+ YI ++ N Sbjct: 20927 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN-------DTGK-YILTIE--N 20976 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 VG ++S S +KV L P+ + + + ++TL W P GGSPI+ Y ++ Sbjct: 20977 GVGEPKSSTVS--VKV---LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE 21031 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+ + W V+ S + +D L+E + + F++ A N GIGEP + +E K Sbjct: 21032 KRDATKRTWSVVSHKCSSTSFKLID-LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE- 21089 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 P P DL+ + TS+++ W P + G S ++ Y V+ + + W + T Sbjct: 21090 ---VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 21146 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG---- 924 ++VS L++ FRV A N G+ P T P+ V+ T E+ D G Sbjct: 21147 E--IEVSQLKEQSVLEFRVFAKNEKGLSDPV-TIGPITVKELIITPEVDLS-DIPGAQVT 21202 Query: 925 -----NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGT 979 N++L + S +W K + + E + + L +KN KE G Sbjct: 21203 VRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGK 21261 Query: 980 YSV 982 Y+V Sbjct: 21262 YTV 21264 Score = 194 bits (493), Expect = 5e-49 Identities = 199/802 (24%), Positives = 323/802 (40%), Gaps = 126/802 (15%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P R P +W + D ++++ + SL ++++ D G YTL + + Sbjct: 16590 LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSS 16647 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G SAF+ VR D P P++L+ + +D V +TW+PP S + Y V++ Sbjct: 16648 GTK--SAFVTVRVLD-----TPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16700 Query: 422 CEVGTNNWVQCNDAPVKIC---KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478 E ++ A V C + + L EG SY FRV A N GI P++ +D + Sbjct: 16701 REATRKSYA----AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV- 16755 Query: 479 DPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRG 538 A+VP PP + +++RN V LSW P G Sbjct: 16756 -----------------------------AEVPQPPGKITVDDVTRNSVSLSWTKPEHDG 16786 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 ++ Y +E S W V+S + + +L +G+ Y+FRV++ N G S+P Sbjct: 16787 GSKIIQYIVEMQAKHSEKWSEC---ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16843 Query: 598 EITSPIQAQDVTVVPS-----APGRVLASRNTKTSVVVQWDRPKHE----------EDLL 642 + PI A+D+ + P + V ++ K V + RPK + Sbjct: 16844 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPIS-GRPKPTITWTKDGLPLKQTT 16902 Query: 643 GYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVI 702 V + T L HK G QY + N VG S E Sbjct: 16903 RINVTDSLDLTTLSIKETHK------------DDGGQY--GITVANVVGQKTASIEI--- 16945 Query: 703 KVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 L P P G + + S+TL W P ++GG I Y + KR+ W V+ Sbjct: 16946 ---VTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 17002 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAG--IGEPSDPSEHFKCEAWTMPEPGPAYDL 819 ++ ++ T L V L G+ Y+F+I A N G SDP + EPGP Sbjct: 17003 ATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI----VAQYPYKEPGPPGTP 17057 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + S+V+ W PV +G SPV GY ++ +E ++ W VN+T + K +L++ Sbjct: 17058 FATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEE 17117 Query: 880 GKTYVFRVRAVNANGVGK---------------PSDTSEPVLVEARPGTKEISAGVDEQG 924 G Y FRV A N GVGK P T EP++V+ T + + V + G Sbjct: 17118 GIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGG 17177 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 ++ G+ E D W K+ + +F + + + + + K G S Sbjct: 17178 SMITGY-IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17236 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAE-HLSP 1043 T +++ +E++ P I + + I F L+A+ H P Sbjct: 17237 DSTGPITA---------------KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKP 17281 Query: 1044 DASYRFIINDREVSDSEIHRIK 1065 + ++ D+E+ +S IK Sbjct: 17282 LPTIEWLRGDKEIEESARCEIK 17303 Score = 193 bits (490), Expect = 1e-48 Identities = 206/864 (23%), Positives = 336/864 (38%), Gaps = 147/864 (17%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 +K+ + G P PV+ W KDG + E + I S L + DT Y Sbjct: 19435 LKINADIAGRPLPVISWAKDG---IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19491 Query: 231 ATNAHG--QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF 288 N G V+ N V+ ++P G P G LE G+T Sbjct: 19492 LKNVAGTRSVAVNCKVL-------DKP----GPPAGP---------------LEINGLTA 19525 Query: 289 RREGETVTLKCTMLVTPDLKRVQPRAEWYRD-DVLLKESK------WTKMFFGEGQ-ASL 340 KC+ L +P+ + D D + E + WT + GE Q S Sbjct: 19526 E--------KCS------LSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSC 19570 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 + L K +E ++ + V++ GV + + ++ DP +P P L+ ++ + Sbjct: 19571 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEITSVTKESMT 19628 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + W P + S + GY ++R E + WV+ N PV + TGL EG Y +RV A Sbjct: 19629 LCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAE 19688 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 N+AG+S PS S + A DP+ L P PP+ Sbjct: 19689 NAAGLSLPSETSPLIRAEDPVFL---------------------------PSPPSKPKIV 19721 Query: 521 EISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGK 579 + + + ++W P G P+ Y +E W+ + ++R Y + L G Sbjct: 19722 DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK--TSIQSLRGTEYTISGLTTGA 19779 Query: 580 SYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV---------- 629 YVFRV S N+ G S+PS+ + P A++ P + S KT +V Sbjct: 19780 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD---IDSEMRKTLIVKAGASFTMTV 19836 Query: 630 ---------VQWDRPKHEEDL-LGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGE 678 V W +P + DL YVD + T+L E N G + + + Sbjct: 19837 PFRGRPVPNVLWSKP--DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19894 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 VK L P P IT+ + S L W VP+ G Sbjct: 19895 SLTLVVK---------------------VLDTPGPPTNITVQDVTKESAVLSWDVPENDG 19933 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+P+ Y+++KRE K W V ++ ++ + V L EG++Y F+++ N G+G P++ Sbjct: 19934 GAPVKNYHIEKREASKKAWVSVTNNCNRLS-YKVTNLQEGAIYYFRVSGENEFGVGIPAE 19992 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E K +P P L + S+ + W P + G S + Y V+ E+ Sbjct: 19993 TKEGVK----ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKN 20048 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W V + + VS L++ Y FRV A N G+ P + PVL++ + EI Sbjct: 20049 W--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDM 20106 Query: 919 GVDEQGNIYLGFDCQEMTD-------ASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 +Y+ D + T + + RF E ++ + LK Sbjct: 20107 KNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKE 20166 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFV 995 D G Y ++ +++ G + +F+ Sbjct: 20167 SVTADAGRYEITAANSSGTTKAFI 20190 Score = 192 bits (489), Expect = 2e-48 Identities = 159/642 (24%), Positives = 274/642 (42%), Gaps = 79/642 (12%) Query: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438 +T P P L ++D V +TW P S ++ Y V+ E G NWV+C A K Sbjct: 19999 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAK 20056 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIA 498 + V+GL E Y FRV A N AG+S P + V + L+ + + Sbjct: 20057 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 20116 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVL--SWEPPTPRGKDPLMYFIEKSVVGSGSW 556 +L+ D + G P + +SR+ V L + T + L +++SV Sbjct: 20117 RAGSNLKVDIPISGKP--LPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGR 20174 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG 616 + A + + K+++ V+ L P T P+ D+T Sbjct: 20175 YEITAANSSGTT----------KAFINIVV------LDRPGPPTGPVVISDIT------- 20211 Query: 617 RVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGL 674 + SV ++W+ PK++ + Y + T +W + + V L Sbjct: 20212 --------EESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS-ATVARTMMKVMKL 20262 Query: 675 TTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVP 734 TTGE+Y FR+KA N G+S++ +S + V+ T P P + N S+T+GW P Sbjct: 20263 TTGEEYQFRIKAENRFGISDHI-DSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20321 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 +GGS ++GY+L+ ++ + W + N + T V ++ G +YEF++ A N AG+G Sbjct: 20322 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20381 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PS PSE + P ++ ++ S+ + W+ P + G S ++GY V+ R+ Sbjct: 20382 KPSHPSE----PVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL 20437 Query: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPV-------- 905 G W + T +S L Q Y FRV A NA G + PS+ P+ Sbjct: 20438 PDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGG 20497 Query: 906 -----------LVEARPGTK-EISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDD 953 +V+ R GT ++ AG+ + A W K +E+ + Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGK-------------PAPTIEWYKDDKELQTN 20544 Query: 954 ERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 +E D + + +K+ D+ + G Y + + + G +S+ + Sbjct: 20545 ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20586 Score = 191 bits (485), Expect = 4e-48 Identities = 214/857 (24%), Positives = 337/857 (39%), Gaps = 113/857 (13%) Query: 177 VQGFPTPVVQWYKDGSLI---CQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATN 233 V G P P ++W K+ ++I A + K + + L I +A +D TY+ A+N Sbjct: 9050 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASN 9109 Query: 234 AHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGE 293 G V N V E + P L ++ D++ E +T+ + Sbjct: 9110 RLGSVFRNVHV---------EVYDRPSPPRNLAVT--------DIK-AESCYLTWDAPLD 9151 Query: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLY 353 + T V + +AEW E ++ L + + + Sbjct: 9152 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRY------------GIWKLIPNGQYEF 9199 Query: 354 TLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 +R V++ G+SD V DP + G PG P L + ++V+W PP S Sbjct: 9200 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---RTKGSMLVSWTPPLDNGGS 9256 Query: 413 PVMGYFVDRCEVGTNNWVQCNDAPV-----KICKYPVTGLFEGRSYIFRVRAVNSAGISR 467 P+ GY++++ E G+ W + + AP+ K ++ V L EG Y FR A+N+AGI Sbjct: 9257 PITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGP 9316 Query: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527 PS SD A DP+ PGPP+ + +++ + Sbjct: 9317 PSEPSDPEVAGDPIF---------------------------PPGPPSCPEVKDKTKSSI 9349 Query: 528 VLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA-QTAVRSPRYAVFDLMEGKSYVFRV 585 L W+PP G P+ Y +E G+ W+RVN + + V +L E + Y FRV Sbjct: 9350 SLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRV 9409 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA---------SRNTKTSVVVQWDRPK 636 + N G SEPS+ T I A D+ P + A S+ +V+ PK Sbjct: 9410 KAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPK 9469 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV-----HGLTTGEQYIFRVKAVNAVG 691 + G G + N V+ TG+ + + A N G Sbjct: 9470 SSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK---YSITAKNKAG 9526 Query: 692 MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751 Q++ +V+ + VP P + + + S L WK+P GG I GY ++KR Sbjct: 9527 -----QKTANCRVKV-MDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT 9580 Query: 752 VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811 + K W +VN T + D L+E Y F++ A N GIG P + + P Sbjct: 9581 IDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYP 9639 Query: 812 EPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED-----AGEWITVNQTT 866 P P L + ++ + WK P G SPV+ Y V+ D W N+ Sbjct: 9640 -PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698 Query: 867 TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEIS----AGVDE 922 V DL +G Y FRV+AVNA GV KPS T P + I V+E Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9758 Query: 923 QGNIYLGFDCQEMTDASQFTWCK-------SYEEISDDERFKIETVGDHSKLYLKNPDKE 975 N+ + + + + TW K + E + D V D L + + Sbjct: 9759 GTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9817 Query: 976 DLGTYSVSVSDTDGVSS 992 D G Y+++ + G +S Sbjct: 9818 DTGLYTITAVNNLGTAS 9834 Score = 188 bits (478), Expect = 3e-47 Identities = 179/740 (24%), Positives = 304/740 (41%), Gaps = 121/740 (16%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 VQW ++ ++ Q K+++ S +H L+I D Y +A + + A Sbjct: 6570 VQWLRNNMVVVQG---DKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAA 6626 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 + D++ + + +G PL+ ++PY + Sbjct: 6627 APKIKTADQD----LVVDVGKPLTMVVPYDAYP--------------------------- 6655 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG-QASLSFSHLHKDDEGLYTLRIVSRGGV 363 + AEW++++ L TK Q S K D+G Y + + ++ G Sbjct: 6656 ------KAEAEWFKENEPLS----TKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6705 Query: 364 SDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 ++ L V D PG +L+ + V + W+ P T S ++GY V+R + Sbjct: 6706 AEGFINLKVIDV-------PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6758 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGR-SYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + WV D + C++ VTGL +G Y+FRV A N G P + V A D Sbjct: 6759 IKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYD 6817 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDP 541 VPGPP V ++++R V L+WEPP G + Sbjct: 6818 ---------------------------VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6850 Query: 542 LMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITS 601 Y IE S W A V D++EG+ Y FRV + NR G+ +PS T Sbjct: 6851 TNYVIELRDKTSIRWDTAMTVRA-EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6909 Query: 602 PIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPC 659 ++ D PS P + +S T++SV ++W+ P + +LGY ++ C G + W C Sbjct: 6910 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRC 6969 Query: 660 NHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ-----ESDVIKVQAALTVPSHP 714 N K + + V GL G +Y++RV A N G+S+ S+ +D V+ + + + Sbjct: 6970 NMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFK 7029 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNS-SPSKPTILTVD 773 G+ ++ + ++ VP P + + + + ++ + S +++ Sbjct: 7030 DGLEVIVPNPITIL----VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPS 7085 Query: 774 GLTEGSLYEFKI--------AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVR 825 ++ +Y K+ +++ I PS P E L F ++ Sbjct: 7086 ERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKE-----------------LKFGDIT 7128 Query: 826 DTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W+ P G SP++GY V+ RE W V T + V DL QGK Y+F Sbjct: 7129 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEF-TVPDLVQGKEYLF 7187 Query: 886 RVRAVNANGVGKPSDTSEPV 905 +V A N G G+P+ EPV Sbjct: 7188 KVCARNKCGPGEPAYVDEPV 7207 Score = 188 bits (477), Expect = 4e-47 Identities = 145/509 (28%), Positives = 233/509 (45%), Gaps = 82/509 (16%) Query: 371 FVRDADPLVTG----APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGT 426 FV ++ LV P P DL+ + ++ V +TW PP S ++ Y ++ +GT Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10388 Query: 427 NNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG------ISRPSRVSDAVAA--- 477 + + + + KY V GL EG +Y +RV AVN G ++P D +A Sbjct: 10389 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10448 Query: 478 ----LDPLDLRRLQAVHLEG-------------EKEIAIYQDDL---------------- 504 D L +R +A L G + E + +DD Sbjct: 10449 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10508 Query: 505 --------------------EGDAQV-----PGPPTG-VHASEISRNYVVLSWEPPTPRG 538 +G QV PGPP G V E++++Y+V+SW+PP G Sbjct: 10509 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10568 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 + Y IEK VG W V + +A + + V L+EGK Y+FR+ + N +G+S+P Sbjct: 10569 GSKITNYIIEKKEVGKDVWMPVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL 10626 Query: 598 EITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL 655 ++ ++A+D VP AP + + + TK S +V W++P H+ + + Y ++ + Sbjct: 10627 -VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKR 10684 Query: 656 WEPCNHKPIG-YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHP 714 W PI Y +F V L G QY FRV A N +G+ + S S + + + PS P Sbjct: 10685 WARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPP 10744 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTV 772 ++ +S+ L W+ P+ GGS ILGY ++ ++V + W N +P T V Sbjct: 10745 VNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKV 10804 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSE 801 GL +G Y+F++ AVN AG +P+ E Sbjct: 10805 TGLRDGQTYKFRVLAVNAAGESDPAHVPE 10833 Score = 187 bits (476), Expect = 5e-47 Identities = 190/783 (24%), Positives = 312/783 (39%), Gaps = 105/783 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + + V R +K+ +G P V W KDG + E + + S+ V + Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTL---KETTRVNVSSSKTVTS 19079 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I A +D TY +N+ G ++ ++V G P R + S P Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPP 19139 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + + + ++E + T W + Sbjct: 19140 EYDGGCQISNY-IVEKKETTSTT-------------------------------WHIVSQ 19167 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHD 393 + S+ L E + + +R G S +S V P PG P + Sbjct: 19168 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPF--SPPGPPGTPKVVH 19225 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 A + ++VTW+ P S V+GY ++ E + W + N + + V+GL EG Y Sbjct: 19226 ATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMY 19285 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 +RV A N AGI + S+ + V A DP D P Sbjct: 19286 EYRVYAENIAGIGKCSKSCEPVPARDPCD------------------------------P 19315 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + I+R V L W P G + Y +E+ + G W + N T ++ + V Sbjct: 19316 PGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCN-YTNIQETYFEV 19374 Query: 573 FDLMEGKSYVFRVLSAN-RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 +L E + Y FRV + N +SEPSE T PI +D P RV+ + +VV+ Sbjct: 19375 TELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKD----DVEPPRVMMDVKFRDVIVVK 19430 Query: 632 -WDRPKHEEDLLGY---YVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------Q 679 + K D+ G + G + E + I + H L T + Q Sbjct: 19431 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN---HTLLTVKDCIRRDTGQ 19487 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y+ +K N G + V+ P G+T C +L W P+ GG Sbjct: 19488 YVLTLK--NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKC-----SLSWGRPQEDGG 19540 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + I Y ++KRE H W + + T V L +G+ Y F++ VN G+GEP + Sbjct: 19541 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19599 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 + +T+P P + ++T V S+ + W P G S +SGY ++ RE+++ W Sbjct: 19600 VAIKALDPFTVPSPPTSLEIT--SVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRW 19657 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS------EPVLVEARPGT 913 + VN+ + +K + L++G Y +RV A NA G+ PS+TS +PV + + P Sbjct: 19658 VRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSK 19717 Query: 914 KEI 916 +I Sbjct: 19718 PKI 19720 Score = 187 bits (475), Expect = 6e-47 Identities = 180/671 (26%), Positives = 294/671 (43%), Gaps = 73/671 (10%) Query: 349 DEGL-YTLR-----IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIV 401 DEGL Y + IV G S S RD DP PG P + R+ V + Sbjct: 18198 DEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP-----PGRPEAIVI---TRNNVTL 18249 Query: 402 TWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVN 461 WK P S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N Sbjct: 18250 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18309 Query: 462 SAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD---LEGDAQVPGPPTGV 517 +AG S PS S A+ A D +D ++ + + I ++ + LE D + P V Sbjct: 18310 AAGNFSEPSDSSGAITARDEIDAPNA-SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV 18368 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM- 576 + + GK+ +E++ R+ ++ ++ V D + Sbjct: 18369 WSKD----------------GKE-----LEETAA------RMEIKSTIQKTTLVVKDCIR 18401 Query: 577 -EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRP 635 +G Y+ ++ + G ++ IT ++ D P P +V T + W+ P Sbjct: 18402 TDGGQYILKLSNV---GGTKSIPIT--VKVLDRPGPPEGPLKVTGV--TAEKCYLAWNPP 18454 Query: 636 KHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMS 693 + ++ Y ++ W + + N + V L G +YIFRV AVN G+ Sbjct: 18455 LQDGGANISHYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIG 18513 Query: 694 ENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 E ES + P P + SM + W P GG+ I GY L+KR+ Sbjct: 18514 E-PLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKE 18572 Query: 754 HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPE 812 W + N L V GLTEG YEF++AA N AG+GEPS+PS ++ C+A + Sbjct: 18573 GVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA--LYP 18630 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTT-TANRY 871 PGP + + +S+ + W P+Y G +PV GY V+ +E A EW T T + Sbjct: 18631 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18690 Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLG-- 929 V+ L++ Y FR+ A+N+ GVG+P+ V+ + R EI D + + L Sbjct: 18691 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18750 Query: 930 -----FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 F + + W K+ ++D R +IE + L + N + D G Y++++ Sbjct: 18751 ATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 18808 Query: 985 SDTDGVSSSFV 995 + G ++FV Sbjct: 18809 ENNSGSKTAFV 18819 Score = 187 bits (474), Expect = 8e-47 Identities = 169/652 (25%), Positives = 277/652 (42%), Gaps = 58/652 (8%) Query: 357 IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 IV G S S RD DP PG P + R+ V + WK P S + Sbjct: 16048 IVGIGKPSKVSECYVARDPCDP-----PGRP---EAIIVTRNSVTLQWKKPTYDGGSKIT 16099 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI-SRPSRVSDA 474 GY V++ E+ W++ + + + VTGL E Y FRV A N+AG+ S PS + A Sbjct: 16100 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16159 Query: 475 VAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPP 534 + A D +D R+ + + + + DA + G P + W Sbjct: 16160 ITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-----------IQWI-- 16206 Query: 535 TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLS 594 +G L + + ++ + AVR ++ +Y+ + + ++ Sbjct: 16207 --KGDQELSNTARLEIKSTDFATSLSVKDAVR---------VDSGNYILKAKN-----VA 16250 Query: 595 EPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAG 652 +T ++ D P P V+ S T + W P + D++ Y V+ Sbjct: 16251 GERSVTVNVKVLDRPGPPEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETS 16308 Query: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712 +W + + V L G +Y FR+ AVN G+ E ES+ + + VP Sbjct: 16309 RLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE-PLESEPVVAKNPFVVPD 16366 Query: 713 HPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 P + SM + W+ P GGS ILGY L+KR+ W + L V Sbjct: 16367 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16426 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVM 831 GL E YEF+++A N AG+ EPS PS + K C+ + +PGP + ++ +S+ + Sbjct: 16427 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDITRSSVFL 16484 Query: 832 LWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKTYVFRVRAV 890 W P+Y G + GY V+ + GEW T N+ ++V L + Y FR+ A+ Sbjct: 16485 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 16544 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG--NIYLG-----FDCQEMTDASQFTW 943 N GVG+ +D P++VE + +I ++ + NI G F + + W Sbjct: 16545 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16604 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 K EI D I+ + L L N ++ D G Y++++ ++ G S+FV Sbjct: 16605 GKVDGEIRD--AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 16654 Score = 186 bits (473), Expect = 1e-46 Identities = 191/764 (25%), Positives = 296/764 (38%), Gaps = 106/764 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++ S++V +K+ + G P P + W KDG + Q + + + + T Sbjct: 16858 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT---RINVTDSLDLTT 16914 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I DD Y N GQ + + +V + P P Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTASIEIVT----------------LDKPDPPKGPV 16958 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 DV E++TL + ++ RD + W + Sbjct: 16959 KFDDV------------SAESITLSWNPPLYTGGCQITNYIVQKRDTT---TTVWDVVSA 17003 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-------GAPGAP 386 + +L + L E + + +R G S F ++DP+V G PG P Sbjct: 17004 TVARTTLKVTKLKTGTEYQFRIFAENRYGQS------FALESDPIVAQYPYKEPGPPGTP 17057 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 ++D +++ W P SPV+GY ++R E + W + N + ++ Sbjct: 17058 F---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN 17114 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L EG Y FRV A N G+ + S+ S+ A DP D Sbjct: 17115 LEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD------------------------ 17150 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAV 565 PG P + + RN + L W P G + Y +EK + G W + + T V Sbjct: 17151 ---PPGTPEPI---MVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF-TNV 17203 Query: 566 RSPRYAVFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 ++ V L E + Y FRV++ N G +S+PS+ T PI A+D +P R+ Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP----RISMDPKF 17259 Query: 625 KTSVVVQ-WDRPKHEEDLLGYYVDCC--VAGTNLWEP---CNHKPIGYNRFVVHG---LT 675 + ++VV + + E D+ G + + G E C K + ++ Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17319 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G QYI R A N G V+ P G+T C +L W P Sbjct: 17320 DGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC-----SLTWSPPL 17372 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I Y ++KRE W V +S L V L EG+ Y F+I AVN G+GE Sbjct: 17373 QDGGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17431 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + + + PGP L + S+ + W P G S + GY V+ R+ Sbjct: 17432 PLESAPVLMKNPFVL--PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRS 17489 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPS 899 WI N+ + L+V+ L + Y FRV A NA GVG+PS Sbjct: 17490 GIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17533 Score = 186 bits (471), Expect = 2e-46 Identities = 169/660 (25%), Positives = 282/660 (42%), Gaps = 64/660 (9%) Query: 352 LYTLRIVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 +Y IV G S +S RD DP PG P + R+ + + W P Sbjct: 17125 VYAENIVGVGKASKNSECYVARDPCDP-----PGTPEPIM---VKRNEITLQWTKPVYDG 17176 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPS 469 S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N+AG IS+PS Sbjct: 17177 GSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17236 Query: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529 + + A D ++L R+ + + + +A V G P + Sbjct: 17237 DSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT-----------I 17285 Query: 530 SWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W RG + + + + + A+R ++G Y+ R + Sbjct: 17286 EWL----RGDKEIEESARCEIKNTDFKALLIVKDAIR---------IDGGQYILRASN-- 17330 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 ++ ++ D P P +V + K S+ W P + D+ Y V+ Sbjct: 17331 ---VAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT--WSPPLQDGGSDISHYVVE 17385 Query: 648 CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707 W + + N V L G +Y+FR+ AVN G+ E + + V+ ++ Sbjct: 17386 KRETSRLAWTVVASEVVT-NSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL-MKNP 17443 Query: 708 LTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP 767 +P P + + N SMT+ W P GGS I+GY ++KR+ W + N Sbjct: 17444 FVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD 17503 Query: 768 TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRD 826 L V GLTE YEF+++A N AG+GEPS + ++K C+ + +PGP + + Sbjct: 17504 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD--PVFKPGPPTNAHIVDTTK 17561 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW-ITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W P+Y G S + GY V+ + D EW I QT ++S L + + Y Sbjct: 17562 NSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKI 17621 Query: 886 RVRAVNANGVG---------KPSDTSE-PVLVEARPGTKEISAGVDEQGNIYLGFDCQEM 935 RV A+N G+G KP D E P L K I I++ F + Sbjct: 17622 RVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPF---KG 17678 Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + TW + E +D + +IE ++++L + N D+ D G Y + + ++ G S+FV Sbjct: 17679 RPTPEITWSREEGEFTD--KVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17736 Score = 186 bits (471), Expect = 2e-46 Identities = 189/804 (23%), Positives = 332/804 (41%), Gaps = 87/804 (10%) Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP-IGLPLSSMIPYTHFDVQFLEKFG 285 + A NA G +S + VV G S G P I LPL YT Sbjct: 20468 FRVFARNAVGSISNPSEVV-----GPITCIDSYGGPVIDLPLE----YTE---------- 20508 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHL 345 V R G +V L+ + P P EWY+DD L+ + + AS+ Sbjct: 20509 VVKYRAGTSVKLRAGISGKP-----APTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20563 Query: 346 HKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + + G Y L++ R + SA + V+ D G PG P++ + A + + + W+P Sbjct: 20564 DRLNSGCYELKL--RNAMGSASATIRVQILDK--PGPPGGPIEFKTVTAEK--ITLLWRP 20617 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + + Y V++ E W ++ ++ C T + +G YIFRVRAVN GI Sbjct: 20618 PADDGGAKITHYIVEKRETSRVVWSMVSEH-LEECIITTTKIIKGNEYIFRVRAVNKYGI 20676 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P SD+V A + PGPP ++I++N Sbjct: 20677 GEPLE-SDSVVAKNAF---------------------------VTPGPPGIPEVTKITKN 20708 Query: 526 YVVLSWEPP-TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 + + W P G D YF+EK S W +V +T +R R V L E Y +R Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET-IRDTRQKVTGLTENSDYQYR 20767 Query: 585 VLSANRHG---LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--E 639 V + N G SEPSE +A D P P ++ + +TK+S+ + W +P ++ Sbjct: 20768 VCAVNAAGQGPFSEPSEF---YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGS 20824 Query: 640 DLLGYYVDCCVAGTNLWEPCNHK-PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 + GY V+ W + K + +VV L G Y FRV AVN G E + Sbjct: 20825 AVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM 20884 Query: 699 SDVIKVQAALTVPSHPYGITL----LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 ++ ++ + L P + L + G + + +P P + + D++ + Sbjct: 20885 NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV--LIPFKGRPPPTVTWRKDEKNLGS 20942 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 + + ++ S ++LT+ +T ++ + N G+GEP + K + P Sbjct: 20943 DARYSIENTDSS-SLLTIPQVTRNDTGKYILTIEN--GVGEPKSSTVSVK----VLDTPA 20995 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 L V ++ +LW P+ G SP+ Y ++ R+ W V+ ++ + K+ Sbjct: 20996 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSF-KL 21054 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPG-TKEISAGVDEQGNIYLGFDCQ 933 DL + + FRV A N G+G+P +T+EPV P +++S + ++ L + Sbjct: 21055 IDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKP 21114 Query: 934 EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993 + S T + ++ + + ++ + ++ + + V + G+S Sbjct: 21115 DFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 21174 Query: 994 FVLDPEELERLMALSNEIKNPTIP 1017 + P ++ L+ ++ E+ IP Sbjct: 21175 VTIGPITVKELI-ITPEVDLSDIP 21197 Score = 185 bits (470), Expect = 2e-46 Identities = 164/638 (25%), Positives = 263/638 (41%), Gaps = 91/638 (14%) Query: 381 GAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC 440 G PG P + + ++ V+WK P S + GY V+R E + WV+ PV Sbjct: 14198 GPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDL 14257 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 + VTGL EG +Y FRV A N AGI PS SD+V D Sbjct: 14258 RCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA-------------------- 14297 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 A PGPP+ H ++ ++ L+W +P G + Y +E VG +W + Sbjct: 14298 -------AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14350 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGR 617 TA+R ++ V DL + Y FR+ + N G+ EP+ I DV +V AP Sbjct: 14351 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIP------DVEIVEREMAPDF 14404 Query: 618 VLASRNTKTSVVVQW----------DRPKHE----EDLLGYYVDCCVAGTNLWE-----P 658 L + +T VV RP E +D + + T + Sbjct: 14405 ELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPE 14464 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT 718 CN G + + V+ ++ G N + +D+ K Sbjct: 14465 CNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK--------------- 14509 Query: 719 LLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 S+TL W +P GGS I Y ++KRE K++ + K T V GL+EG Sbjct: 14510 ------DSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLSEG 14562 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 Y F++ A N GIGEP++ +E K P P L ++ +++ + W P + Sbjct: 14563 CEYFFRVMAENEYGIGEPTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKH 14618 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G S ++GY ++ + + + +W + TT V +L +G+ Y F+V AVN+ G P Sbjct: 14619 DGGSKITGYVIEAQRKGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14676 Query: 899 SDTSEPVLVEARPGTKEISA-GVDEQGNIYLGFDCQEMT------DASQFTWCKSYEEIS 951 + S PV+V+ + E+ G+ ++ I D ++ TW K + + Sbjct: 14677 RE-SRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK 14735 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 +R ET + L + + D G Y ++ + G Sbjct: 14736 QTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG 14773 Score = 185 bits (470), Expect = 2e-46 Identities = 164/623 (26%), Positives = 257/623 (41%), Gaps = 58/623 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P + D R+ V ++W+ P S ++GY V+ G++ W C A VK+ + Sbjct: 15677 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEA 15734 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 +TGL +G Y FRV A N GIS P ++S V A D L A L + + Sbjct: 15735 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---LVIPPAFKLLFNTFTVLAGE 15791 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQ 562 DL+ D G PT ++W K V RVNA+ Sbjct: 15792 DLKVDVPFIGRPTPA-----------VTWH---------------KDNVPLKQTTRVNAE 15825 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PSAP-GRVL 619 + + + D + V N G I+ +V V+ P P G V Sbjct: 15826 STENNSLLTIKDACREDVGHYVVKLTNSAG--------EAIETLNVIVLDKPGPPTGPVK 15877 Query: 620 ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTG 677 T S+ + W PK++ + Y V+ T W+ + + L TG Sbjct: 15878 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-ATVARTTIKACRLKTG 15936 Query: 678 EQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFS 737 +Y FR+ A N G S + Q VP P + SM + W P Sbjct: 15937 CEYQFRIAAENRYGKSTYLNSEPTV-AQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISD 15995 Query: 738 GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPS 797 GGS ++GY+L+++E + W ++N +P T GL EG YEF+++A N+ GIG+PS Sbjct: 15996 GGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPS 16055 Query: 798 DPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAG 857 SE + P P + V S+ + WK P Y G S ++GY V+ +E G Sbjct: 16056 KVSECYVARDPCDPPGRPEAII----VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 16111 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLVEARPGTKEI 916 W+ + T + + +V+ L + Y FRV A NA GV +PS+++ + I Sbjct: 16112 RWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRI 16171 Query: 917 SAGVDEQGNIYLGFDCQEMTDASQF-------TWCKSYEEISDDERFKIETVGDHSKLYL 969 S + I + DA + W K +E+S+ R +I++ + L + Sbjct: 16172 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231 Query: 970 KNPDKEDLGTYSVSVSDTDGVSS 992 K+ + D G Y + + G S Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERS 16254 Score = 185 bits (469), Expect = 3e-46 Identities = 198/834 (23%), Positives = 347/834 (41%), Gaps = 94/834 (11%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +++L ++G P P V W K+ P K RI+ LEI A +D YS Sbjct: 10863 TLRLSAIIKGVPFPKVTWKKE-----DRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10917 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 N G + + V+V ++P G P L +S + R Sbjct: 10918 TVENPAGSKTVSVKVLVL-----DKP----GPPRDLEVSEI------------------R 10950 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 ++ +T K + D V R DV ++W+ + + S HL++ + Sbjct: 10951 KDSCYLTWKEPL---DDGGSVITNYVVERRDVA--SAQWSPLSATSKKKSHFAKHLNEGN 11005 Query: 350 EGLYTLRIVSRGGVSDHSAFLF----VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + L+ + ++ G F+ ++ DPL PG P DL D ++ V + W Sbjct: 11006 QYLFRVAAENQYG---RGPFVETPKPIKALDPL--HPPGPPKDLHHVDVDKTEVSLVWNK 11060 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P+ SP+ GY V+ E GT +W++ C VTGL +G++Y FRV+A N G+ Sbjct: 11061 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV--VTGLQQGKTYRFRVKAENIVGL 11118 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P P++ + + V E ++ + +EG G T V I R Sbjct: 11119 GLPDTTI-------PIECQE-KLVPPSVELDVKL----IEGLVVKAG--TTVRFPAIIRG 11164 Query: 526 YVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRV 585 P P K + + S + + + +T S + + + + +++ Sbjct: 11165 V-------PVPTAK----WTTDGSEIKTD--EHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643 +N G + + DV P+ P +L T + + W PK + ++ Sbjct: 11212 TVSNAAG---SKTVAVHLTVLDVPGPPTGPINILDV--TPEHMTISWQPPKDDGGSPVIN 11266 Query: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 Y V+ + W + + H L G +Y+FRV+A N +G+ + + Sbjct: 11267 YIVEKQDTRKDTWGVVSSGSSKTKLKIPH-LQKGCEYVFRVRAENKIGVGPPLDSTPTV- 11324 Query: 704 VQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + + PS P + + ++ T+ W +PK GGSPI GYY+++REV K W VN + Sbjct: 11325 AKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVNKT 11383 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 P V GL EG+ YEF++ A NLAG+ +PS S+ K P PGP + + Sbjct: 11384 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKP-PGPPINPKLKD 11442 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKT 882 + ++W P+ G SP+ GY V+ ++ +W +N+ + +V L +G Sbjct: 11443 KSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNE 11502 Query: 883 YVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNIYLGFDCQEMTDAS- 939 Y FR++A N G G+P + +E V+ + P E+ + + +G + + Sbjct: 11503 YRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKG 11562 Query: 940 ----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 TW K + + ++R + +L +K + D G Y +S ++ G Sbjct: 11563 RPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11616 Score = 185 bits (469), Expect = 3e-46 Identities = 204/870 (23%), Positives = 337/870 (38%), Gaps = 134/870 (15%) Query: 161 RSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 ++H V S++L QG PTP W K S + A+ I + TL + + Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHTTDSFSTLTVENCN 22047 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFR-------SVGLPIGLPLSSMIPY 273 +D Y+ N G S V V G P S L PL Sbjct: 22048 RNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGAR 22107 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 H V +EK + RR + ++ KCT + Sbjct: 22108 IHHYV--VEKREAS-RRSWQVISEKCTRQI------------------------------ 22134 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV-TGAPGAPMDLQCH 392 + L + + + V+ GV + +P+V T P P L Sbjct: 22135 ------FKVNDLAEGVPYYFRVSAVNEYGVGEPYEM-----PEPIVATEQPAPPRRLDVV 22183 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 D ++ ++ W P+ S + GY ++ + G++ WV+ K + V L E Sbjct: 22184 DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTFTVERLVEKTE 22241 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y FRV+A N AG S P +V +P +E ++ + L G Sbjct: 22242 YEFRVKAKNDAGYSEPREAFSSVIIKEP---------QIEPTADLTGITNQLI--TCKAG 22290 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + R ++W+ R K+ RV+ T V Sbjct: 22291 SPFTIDVPISGRPAPKVTWKLEEMRLKET---------------DRVSITTTKDRTTLTV 22335 Query: 573 FDLMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 D M G S + + N G + P +T PI+ V+ Sbjct: 22336 KDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSA------------ 22383 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 S V+ W PK ++ Y V+ +GT W+ N + + V LT +Y Sbjct: 22384 ---ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEY 22439 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 FRV + N G+S+ + + +I + PS P + + ++M++ W+ P GGS Sbjct: 22440 SFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGS 22498 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I+GY+++K+E + W + N P V GL EG Y+F+ A+N AG+ + S+ S Sbjct: 22499 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 22558 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFR---EEDAG 857 + + PG +V +++ ++W AP Y G S V GY ++ + E G Sbjct: 22559 RPIMAQN-PVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 22614 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLV--EARPGTK 914 W+ N T ++ + V+ L +G TY FRV A NA GV K S+++ PV E P Sbjct: 22615 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 22674 Query: 915 EISAGV-DEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 E+ A + + I G D + DA+ + W K +E+ E+ ++ G + Sbjct: 22675 ELDARLHGDLVTIRAGSDL--VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT 22732 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFVL 996 +K D+ D G Y+++V + G + V+ Sbjct: 22733 AVIKFCDRSDSGKYTLTVKNASGTKAVSVM 22762 Score = 184 bits (466), Expect = 7e-46 Identities = 162/629 (25%), Positives = 274/629 (43%), Gaps = 63/629 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG +DL+ ++ + WK P++ S ++GY VD N W + + +Y Sbjct: 13512 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKS--LSLQY 13568 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVS----DAVAALDPLDLRRLQAVHLEGEKEIA 498 L EG+ Y FRV A N G PS ++ D V A D LDL+ L + Sbjct: 13569 SAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPD-LDLKGLPDL--------- 13618 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 Y + ++ P G A +S W+ +G+DPL + R Sbjct: 13619 CYLAKENSNFRLKIPIKGKPAPSVS-------WK----KGEDPL-----------ATDTR 13656 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V+ +++ + V+D + + + + N G E T I+ +P+ P + Sbjct: 13657 VSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG---TISIKVVGKPGIPTGP--I 13711 Query: 619 LASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTT 676 T ++ ++W PK + ++ Y ++ + N W C + F V L Sbjct: 13712 KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCA-SAVQKTTFRVTRLHE 13770 Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +Y FRV A N G+ E + S+ I + VP P +++ S++L W PK Sbjct: 13771 GMEYTFRVSAENKYGVGEGLK-SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKK 13829 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 +GGSPI GY+L+ +E + W N +P + V GLTEG YEF++ A+NLAG+G+P Sbjct: 13830 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13889 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S PSE + P + S+ ++W P Y G ++GY V+ R+ + Sbjct: 13890 SLPSE----PVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPS 13945 Query: 857 GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVN-ANGVGKPSDTSEPVLV--EARPGT 913 W+ N V+DL +G Y FR+RA N A + PS+++E ++ E T Sbjct: 13946 KSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPT 14005 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 + + + I G D + S + +W K+ ++I + +I + S Sbjct: 14006 IVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 14064 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 L +K ++D G Y+++ ++ G V Sbjct: 14065 LTIKYATRKDAGEYTITATNPFGTKVEHV 14093 Score = 184 bits (466), Expect = 7e-46 Identities = 157/633 (24%), Positives = 259/633 (40%), Gaps = 56/633 (8%) Query: 283 KFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSF 342 K G+T + G+T+ L ++ L P++ W + ++ S T++ + L+ Sbjct: 14013 KDGLTIKA-GDTIVLNAISILGKPL----PKSSWSKAGKDIRPSDITQITSTPTSSMLTI 14067 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + + D G YT+ + G V V PG P ++ + + + +T Sbjct: 14068 KYATRKDAGEYTITATNPFGTK-------VEHVKVTVLDVPGPPGPVEISNVSAEKATLT 14120 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W PP SP+ Y +++ E W ++ ++ C++ T L +G YIFRV AVN Sbjct: 14121 WTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNH 14179 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 G P + S+ V +D PGPP S + Sbjct: 14180 YGKGEPVQ-SEPVKMVDRFG---------------------------PPGPPEKPEVSNV 14211 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 ++N +SW+ P G + Y +E+ S W R +T V R V L EG +Y Sbjct: 14212 TKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTY 14270 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE-- 639 FRV + NR G+ PSE + + +D P P + TK S + W +P ++ Sbjct: 14271 EFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGL 14330 Query: 640 DLLGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 ++ GY V+ G W + + +FVV L T E+Y FR+ A+N G+ E + Sbjct: 14331 EITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14390 Query: 699 SDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWH 758 DV V+ + P L L ++ G P K ++ KN Sbjct: 14391 PDVEIVEREM-APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRA 14449 Query: 759 EVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818 + ++ S T+L + +F + N AG + + PGP + Sbjct: 14450 NIENTESF-TLLIIPECNRYDTGKFVMTIENPAG-------KKSGFVNVRVLDTPGPVLN 14501 Query: 819 LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQ 878 L ++ S+ + W P+ G S ++ Y V+ RE + T Y KV+ L Sbjct: 14502 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLS 14560 Query: 879 QGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP 911 +G Y FRV A N G+G+P++T+EPV P Sbjct: 14561 EGCEYFFRVMAENEYGIGEPTETTEPVKASEAP 14593 Score = 184 bits (466), Expect = 7e-46 Identities = 233/952 (24%), Positives = 374/952 (39%), Gaps = 107/952 (11%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR---CEVGTNNWVQCNDAPVK 438 APG P + D R V + W P S V+GY ++R EVG W++CN V Sbjct: 22569 APGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22625 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQA-VHLEGEKE 496 + VT L EG +Y FRV A N+AG IS+ S + V D + + L G+ Sbjct: 22626 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22685 Query: 497 IAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK-DPLMYFIEKSVVGSGS 555 DL DA V G P EP K D + EK Sbjct: 22686 TIRAGSDLVLDAAVGGKP-----------------EPKIIWTKGDKELDLCEK------- 22721 Query: 556 WQRVNAQ-TAVRSPRYAVF-DLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS 613 V+ Q T R+ F D + Y V +A+ G S + + + P Sbjct: 22722 ---VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNAS--GTKAVSVMVKVLDS------PG 22770 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV 671 G++ SR T+ + W P+ + ++ Y V+ W + + +VV Sbjct: 22771 PCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVV 22829 Query: 672 HGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGW 731 L +YIFRV+AVN G ES+ I + + T+PS P + + + W Sbjct: 22830 TRLIKNNEYIFRVRAVNKYGPGV-PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQW 22888 Query: 732 KVPKFSGGSPILGYYLDKREVHHKNWHEVNSS-PSKPTILTVDGLTEGSLYEFKIAAVNL 790 P+ GG+ I Y +DKRE W VN T L V L EG Y+F++ AVN Sbjct: 22889 TKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNA 22948 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 AG EPS+ S C + PGP + S+ + W P+Y G + + GY ++ Sbjct: 22949 AGNSEPSEASNFISCREPSYT-PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 23007 Query: 851 FREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT---SEPVL 906 +E+D +W V+ T N V DL+ G+ Y FRV AVN G+ + S++ EPV Sbjct: 23008 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 23067 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETV 961 P E++ + + I G + M S TW K +++ R I+T Sbjct: 23068 RIEIPDL-ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTT 23124 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSE 1021 +S L + ++ D G Y++ + G S+ VL ++ + P S Sbjct: 23125 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL------------VKVYDTPGPCPSV 23172 Query: 1022 LAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRI--KCDKA----TGIIEM 1075 E+ W +I+ RE + + KC K +G++E Sbjct: 23173 KVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEG 23232 Query: 1076 VMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEY 1135 M F + E Y + G+ S VL+ + L A+ + + + Sbjct: 23233 TMYYFRVLPENIYGI----GEPCETSDAVLVSE---VPLVPAKLEVVDVTKS-----TVT 23280 Query: 1136 LHWD-VTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKD 1194 L W+ + RL V K +W+K + L+ + E + L++ + Sbjct: 23281 LAWEKPLYDGGSRLTGYVLEACKAGTERWMK---------VVTLKPTVLEHTVTSLNEGE 23331 Query: 1195 HGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMK 1254 ++ ++++G + D L + S P K + P G ++ + Sbjct: 23332 QYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTIDLSTMPQKTIHVPAGRPVELVIP 23389 Query: 1255 YF-TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEI 1305 +W +K+ SE + + ++A L I E T +D G+YT E+ Sbjct: 23390 IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23441 Score = 182 bits (462), Expect = 2e-45 Identities = 157/621 (25%), Positives = 254/621 (40%), Gaps = 75/621 (12%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 LV P R P A W+ L+ES+ + A L+ D G YTL + + Sbjct: 23386 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23445 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G + + + + D G P P+ + DA + ++W+PP +P+ GY V++ Sbjct: 23446 GTTSETIKVIILDKP----GPPTGPIKIDEIDATS--ITISWEPPELDGGAPLSGYVVEQ 23499 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 + W+ +++ + + T L EG Y+FRV A N GI Sbjct: 23500 RDAHRPGWLPVSESVTR-STFKFTRLTEGNEYVFRVAATNRFGIGS-------------- 23544 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 LQ+ +E I ++PGPP + ++SR+ + L+W PP G Sbjct: 23545 ---YLQSEVIECRSSI-----------RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ 23590 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ V + W RVN + V RY L EG Y RV + N G +PS + Sbjct: 23591 VTGYIVERKEVRADRWVRVN-KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23649 Query: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEP 658 PI A D P P + T+TSV + W P+ E + GY ++ + W Sbjct: 23650 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23709 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY--- 715 CN P + + L G +Y FRV A NA G E ++ +KV L P + Sbjct: 23710 CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDER 23769 Query: 716 ---GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 GI + +T+ K F PI + + +++ + + + ++ I Sbjct: 23770 YQEGIFVRQGGVIRLTIPIKGKPF----PICKWTKEGQDISKRAMIATSETHTELVIKEA 23825 Query: 773 DGLTEGSLYEF--------KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEV 824 D G+ Y+ K + + IG P+ P GP L + ++ Sbjct: 23826 DRGDSGT-YDLVLENKCGKKAVYIKVRVIGSPNSPE-------------GP---LEYDDI 23868 Query: 825 RDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 + S+ + W+ P G + + GY ++ RE W T++ L V L++ Y Sbjct: 23869 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTS-LVVKGLKENVEYH 23927 Query: 885 FRVRAVNANGVGKPSDTSEPV 905 FRV A N G+ KP + EPV Sbjct: 23928 FRVSAENQFGISKPLKSEEPV 23948 Score = 182 bits (461), Expect = 3e-45 Identities = 173/685 (25%), Positives = 271/685 (39%), Gaps = 56/685 (8%) Query: 238 VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS----SMIPYTHFDVQFLEKFGVTFRREGE 293 VS N V GD FR + +S S P T D K + R G+ Sbjct: 22624 VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 22683 Query: 294 TVTLKCTMLVTPDLK---RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 VT++ + D + +P+ W + D L + + + +A+ + D Sbjct: 22684 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22743 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G YTL + + G S + V D+ PG L ++ + W P Sbjct: 22744 GKYTLTVKNASGTKAVSVMVKVLDS-------PGPCGKLTVSRVTQEKCTLAWSLPQEDG 22796 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y V+R E NWV + Y VT L + YIFRVRAVN G Sbjct: 22797 GAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAVNKYG------ 22849 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 V +E E +A +P PP + ++++ Sbjct: 22850 ----------------PGVPVESEPIVA------RNSFTIPSPPGIPEEVGTGKEHIIIQ 22887 Query: 531 W-EPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W +P + G + Y ++K S W RVN V R V LMEG Y FRV + N Sbjct: 22888 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22947 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G SEPSE ++ I ++ + P P TK S+ + W +P ++ D++GY ++ Sbjct: 22948 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 23007 Query: 648 CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 T+ W + + I F V L G++Y FRV AVN GMSE S+ I+ Sbjct: 23008 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 23067 Query: 707 ALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK 766 + +P L ++ G P K+ + + ++++ S Sbjct: 23068 RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY 23127 Query: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826 ++L VD + ++ I A N +G + PGP + EV Sbjct: 23128 -SLLIVDKVNRYDAGKYTIEAENQSG-------KKSATVLVKVYDTPGPCPSVKVKEVSR 23179 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFR 886 S+ + W+ P G +PV+ Y V+ RE + TV + Y ++S L +G Y FR Sbjct: 23180 DSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLY-RISGLVEGTMYYFR 23238 Query: 887 VRAVNANGVGKPSDTSEPVLVEARP 911 V N G+G+P +TS+ VLV P Sbjct: 23239 VLPENIYGIGEPCETSDAVLVSEVP 23263 Score = 181 bits (460), Expect = 4e-45 Identities = 159/669 (23%), Positives = 274/669 (40%), Gaps = 82/669 (12%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ PG P + + D R V + W P S V GY ++ +V + W +CN Sbjct: 23656 DPIAP--PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 23713 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR--RLQAVHLEG 493 P KI +Y +T L +G Y FRV A N+ G P+ V V + L+ L + EG Sbjct: 23714 PTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEG 23773 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGS 553 I + Q G ++ P G + + + W T G+D I K Sbjct: 23774 ---IFVRQG---GVIRLTIPIKG-------KPFPICKW---TKEGQD-----ISK----- 23807 Query: 554 GSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHG----------LSEPSEITSPI 603 R T+ + + G S + ++ N+ G + P+ P+ Sbjct: 23808 ----RAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23863 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 + D+ V SV V W P + D+LGY ++ W + Sbjct: 23864 EYDDIQV---------------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23908 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT-LL 720 + G + VV GL +Y FRV A N G+S+ + + + + L P P +L Sbjct: 23909 RVRGTS-LVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVL 23967 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + S++L W PK GGS + GYY++++E W N + T+ TV GL + Sbjct: 23968 DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAE 24027 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G+ E S SE C+ +P +L + S+ + W+ P G Sbjct: 24028 YQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSISKDSVTLQWEKPECDG 24086 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + GY+V++R+ W N+ ++ + L + Y FRV A N G+ +P Sbjct: 24087 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24146 Query: 901 TSEPVLVEARPG--------TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 T+ + + G K+++ + E + + + D W + +E+ Sbjct: 24147 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD---IKWYRFGKELIQ 24203 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 ++K+ + G L + ++ED G Y+ ++++ V + E +L+ + Sbjct: 24204 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGEVETSSKLLLQATPQF 24256 Query: 1013 NPTIPLKSE 1021 +P PLK + Sbjct: 24257 HPGYPLKEK 24265 Score = 179 bits (453), Expect = 2e-44 Identities = 155/603 (25%), Positives = 260/603 (43%), Gaps = 78/603 (12%) Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGA---- 382 +W ++ G L + E + +R V++ G S+ S +DP++ Sbjct: 7657 EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS-----EPSDPVLCREKLYP 7711 Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P L+ + ++ + W P SP+ Y V++ +V W Q D VK K Sbjct: 7712 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKC 7770 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 VT L EG Y+FRV A N+ G S + + D+V A D Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT-------------------- 7810 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA 561 PGPP + ++++ +V L WEPP G P+ Y IEK W + Sbjct: 7811 -------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG- 7862 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +TA + V D++EG F+V + N G+ PSE T + +D T PS P + + Sbjct: 7863 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 7922 Query: 622 RNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH-GLTTGE 678 + + + W P+ ++GY+V+ C GT W N +PI +F V G+ + Sbjct: 7923 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 7982 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQ---AALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +Y+ RV+AVNA+G+SE S+ S+ + + T+ + I ++ +G +++ VP Sbjct: 7983 EYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVI--EGEKLSI--PVPF 8038 Query: 736 FSGGSPILGYYLDKREVHH------KNWHEVNSSPSKPTILTVDGLTEGSLYEFKI---- 785 + P + ++ D +EV KN H +++ P + D E K+ Sbjct: 8039 RAVPVPTVSWHKDGKEVKASDRLTMKNDH-ISAHLEVPKSVRADAGIYTITLENKLGSAT 8097 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 A++N+ IG P GP D+ ++ +S + W+ P + G +P+ Sbjct: 8098 ASINVKVIGLP-----------------GPCKDIKASDITKSSCKLTWEPPEFDGGTPIL 8140 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE +I V + V DL Y FRV+AVN G G+ + PV Sbjct: 8141 HYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV 8199 Query: 906 LVE 908 + + Sbjct: 8200 IAQ 8202 Score = 177 bits (450), Expect = 5e-44 Identities = 166/627 (26%), Positives = 257/627 (40%), Gaps = 66/627 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK- 441 PG P + D + V + W P S ++GYFV+ C++ + WV+CN AP +I + Sbjct: 12821 PGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12877 Query: 442 -YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 Y TGL E Y FR A + IS PS SD V L A ++ ++++ Sbjct: 12878 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL---------AENVPPRIDLSVA 12928 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVN 560 L G + A+ + +SW+ KD + K G + N Sbjct: 12929 MKSLL--TVKAGTNVCLDATVFGKPMPTVSWK------KDGTLL---KPAEGIKMAMQRN 12977 Query: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 T +F + S + + + N G T ++ D P P V Sbjct: 12978 LCTL------ELFSVNRKDSGDYTITAENSSG---SKSATIKLKVLDK---PGPPASVKI 13025 Query: 621 SRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 ++ ++ W+ P + ++ Y VD W + + V L G Sbjct: 13026 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVS-ATVPITSCSVEKLIEGH 13084 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI----TLLNCDGHSMTLGWKVP 734 +Y FR+ A N G+ + V A P P G + N MT+ WK P Sbjct: 13085 EYQFRICAENKYGVGD-----PVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPP 13139 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 GGSPI GY L+KRE NW +VN P L GL EG+ YEF++ A+N AG G Sbjct: 13140 ADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPG 13199 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PSD S+ P PA+ + R +S+ + W P Y G SP+ GY V+ + Sbjct: 13200 KPSDASKAAYARDPQYPPGPPAFPKVYDTTR-SSVSLSWGKPAYDGGSPIIGYLVEVKRA 13258 Query: 855 DAGEWITVN--QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLV 907 D+ W+ N Q R+ +V+ L + Y FRV AVN G PSD + +L+ Sbjct: 13259 DSDNWVRCNLPQNLQKTRF-EVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13317 Query: 908 EARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVG 962 P E+ A + + + G + + TW K + D I++ Sbjct: 13318 ---PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD 13374 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L +N +K D G Y +++ ++ G Sbjct: 13375 FDTFLRCENVNKYDAGKYILTLENSCG 13401 Score = 176 bits (445), Expect = 2e-43 Identities = 164/628 (26%), Positives = 264/628 (42%), Gaps = 59/628 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + + R+ V + W P + GY V++ ++ + +W++ N V C + Sbjct: 13905 PGKP---EVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAF 13961 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 VT L EG Y FR+RA N+AG IS PS ++ + D E E + Sbjct: 13962 TVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD------------EYEAPTIVLD 14009 Query: 502 DDLEGDAQVPGPPTGV--HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 ++ + T V S + + SW + GKD I + + + + + Sbjct: 14010 PTIKDGLTIKAGDTIVLNAISILGKPLPKSSW---SKAGKDIRPSDITQ-ITSTPTSSML 14065 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV--VPSAPGR 617 + A R A + ++ + + ++ VTV VP PG Sbjct: 14066 TIKYATRK-------------------DAGEYTITATNPFGTKVEHVKVTVLDVPGPPGP 14106 Query: 618 VLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLT 675 V S + + W P + + Y ++ LW + + I R V L Sbjct: 14107 VEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLI 14165 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G +YIFRV AVN G E Q S+ +K+ P P + N ++ T+ WK P Sbjct: 14166 QGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14224 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I GY++++RE W +P V GL EGS YEF+++A N AGIG Sbjct: 14225 DDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGP 14284 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 PS+ S+ + P PGP + + S + W P Y G ++GY V+ ++ Sbjct: 14285 PSEASDSVLMKDAAYP-PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14343 Query: 856 AGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGT 913 WI + T TA R + V DLQ + Y FR+ A+N GVG+P+ + +VE Sbjct: 14344 DEAWIK-DTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAP 14402 Query: 914 K-EISAGVDEQGNIYLGFDCQ-----EMTDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 E+ A + + G + + A + TW K + I+ R IE + L Sbjct: 14403 DFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLL 14460 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ D G + +++ + G S FV Sbjct: 14461 IIPECNRYDTGKFVMTIENPAGKKSGFV 14488 Score = 174 bits (442), Expect = 4e-43 Identities = 154/640 (24%), Positives = 249/640 (38%), Gaps = 84/640 (13%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + +++ + V W PP + GYF+++ E + WV N + + + Sbjct: 12024 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 12083 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 V L Y FRV+A N GI PS S V A DP++ Sbjct: 12084 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE-------------------- 12123 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE-KSVVGSGS----W 556 PGPPT + +++ + L W P G P++ Y +E + + S W Sbjct: 12124 -------PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--- 613 +R NA + + V L E + Y FRV + N+ G+ P+E+ I+ +++ P Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236 Query: 614 -------------APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 P R+ A + + V W + + + VD L P + Sbjct: 12237 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNS 12296 Query: 661 HKPIGYNRFVVHGLTTGEQYIF-RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITL 719 + + GE+ +F V+ ++ G + + SDV K Sbjct: 12297 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT--------------- 12341 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGS 779 S + W P+ GGS + Y ++KRE K W V K T V L G+ Sbjct: 12342 ------SCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKK-TSFHVTNLVPGN 12394 Query: 780 LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYS 839 Y F++ AVN G G P+D + + EP P L E+ S + W P+ Sbjct: 12395 EYYFRVTAVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRD 12453 Query: 840 GSSPVSGYFVDFREED--AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G + + GY +REE+ A W + + L V+ L++GK Y FRV A NA GV Sbjct: 12454 GGAKIDGYITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSL 12511 Query: 898 PSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDA-----SQFTWCKSYEEISD 952 P + + EA+ + EQ I G + W K +E+ Sbjct: 12512 PREAEG--VYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVT 12569 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 + S L +K+ ++D G YS++ ++ G + Sbjct: 12570 SSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDT 12609 Score = 173 bits (439), Expect = 1e-42 Identities = 157/607 (25%), Positives = 254/607 (41%), Gaps = 62/607 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + + + S + + + L + + D G Y+L + G + Sbjct: 12556 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12615 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V DA G P P D+ D + D ++W P S + Y V++C+V +WV Sbjct: 12616 VMDAP----GPPQPPFDIS--DIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVT 12669 Query: 432 CNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490 + K C+ V L G+ YIFRVRA N GIS P Sbjct: 12670 ALASVTKTSCR--VGKLIPGQEYIFRVRAENRFGISEP---------------------- 12705 Query: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKS 549 L K +A + VP P ++++++ + ++W+ P G P++ Y IE+ Sbjct: 12706 LTSPKMVAQFPFG------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK 12759 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W + N T VRS Y L+EG Y FR+ + N+ G S PS+ T + A+ + Sbjct: 12760 ERNSLLWVKAN-DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MP 12817 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 V P PG+ TK++V + W RPKH+ ++GY+V+ C + W CN P I Sbjct: 12818 VDP--PGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12875 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC--- 722 + GL QY FR A AV +S S+ SD + + A P + + + Sbjct: 12876 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 12935 Query: 723 -DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781 G ++ L V F P + + D + ++ + T L + + Sbjct: 12936 KAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT-LELFSVNRKDSG 12992 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 ++ I A N +G S+ + + +PGP + ++ ++ W+ P+ G Sbjct: 12993 DYTITAENSSG-------SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 13045 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y VD RE W V+ T V L +G Y FR+ A N GVG P T Sbjct: 13046 SEITNYIVDKRETSRPNWAQVSATVPITS-CSVEKLIEGHEYQFRICAENKYGVGDPVFT 13104 Query: 902 SEPVLVE 908 EP + + Sbjct: 13105 -EPAIAK 13110 Score = 172 bits (437), Expect = 2e-42 Identities = 163/628 (25%), Positives = 259/628 (41%), Gaps = 61/628 (9%) Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQ-ASLSFSHLHKDDE 350 GET L+ + P P W +D L+E+ Q +L + D Sbjct: 18350 GETFVLEADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G Y L++ + GG + V D G P P+ + A + Y+ W PP Sbjct: 18405 GQYILKLSNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDG 18458 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y +++ E +W Q + V+ Y VT L G YIFRV AVN GI P Sbjct: 18459 GANISHYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE 18517 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 S V A +P + PGPP+ S I+++ +V++ Sbjct: 18518 -SGPVTACNPY---------------------------KPPGPPSTPEVSAITKDSMVVT 18549 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W P G + Y +EK W + N +T + R V L EG SY FRV + N Sbjct: 18550 WARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAEN 18608 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G+ EPSE + +A D P P + +++SV + W +P ++ + GY V+ Sbjct: 18609 AAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVE 18668 Query: 648 CCVAGTNLWEPCNHKPIGY--NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ 705 A + W C P G +F V L +Y FR+ A+N+ G+ E + + Q Sbjct: 18669 VKEAAADEWTTCT-PPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQ 18727 Query: 706 AALTVPSHPYGITLLNCD--GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + P L S TL V P + + + + + EV SS Sbjct: 18728 ERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS 18787 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 T+L +D +T + + N +G S+ + P +LT E Sbjct: 18788 ---FTMLVIDNVTRFDSGRYNLTLENNSG-------SKTAFVNVRVLDSPSAPVNLTIRE 18837 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTY 883 V+ S+ + W+ P+ G + ++ Y V+ RE + T+ T + ++ +LQ+G +Y Sbjct: 18838 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTF-RIENLQEGCSY 18896 Query: 884 VFRVRAVNANGVGKPSDTSEPVLVEARP 911 FRV A N G+G P++T+EPV V P Sbjct: 18897 YFRVLASNEYGIGLPAETTEPVKVSEPP 18924 Score = 172 bits (436), Expect = 2e-42 Identities = 149/603 (24%), Positives = 243/603 (40%), Gaps = 66/603 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R P W R++ + ++ G LS + ++D G Y L++ + G SA Sbjct: 17679 RPTPEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG--SKSA 17734 Query: 369 FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNN 428 F+ V+ D PG P +L + +D + W+PP + V Y +D+ E Sbjct: 17735 FVTVKVLD-----TPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17789 Query: 429 WVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488 + + K + V L EG Y FRV A N G+ P DAV A +P Sbjct: 17790 YANVSSKCSKT-SFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-------- 17840 Query: 489 VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE 547 P PP V +++S+ L WE P G ++ Y +E Sbjct: 17841 ----------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17878 Query: 548 KSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD 607 G+ W V + V L G+ Y FRV + N G S+P + P+ A+D Sbjct: 17879 MQPKGTEKWSIVAESKVCNA---VVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17935 Query: 608 VTVVPSA-----PGRVLASRNTKTSV-VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH 661 +T+ PS + A + K + V+ RP + G L + Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN---------ISWVKDGEPLKQTTRV 17986 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLL 720 V + G + F V A + + E+ + V L P P G + Sbjct: 17987 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV---LEKPGPPVGPVRFD 18043 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + + W+ P ++GG I Y ++KR+ WH V+++ ++ TI + L G+ Sbjct: 18044 EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTE 18102 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G P D + EPGP + +++ W PV G Sbjct: 18103 YQFRIFAENRYGKSAPLDSKA--VIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG 18160 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + + GY ++ +E+++ W+ +N+T + K + L +G Y F+V A N G+GKPS Sbjct: 18161 GTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18220 Query: 901 TSE 903 SE Sbjct: 18221 VSE 18223 Score = 172 bits (435), Expect = 3e-42 Identities = 170/703 (24%), Positives = 284/703 (40%), Gaps = 123/703 (17%) Query: 353 YTLRIVSRG--GVSDHSA-FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTT 409 Y R+ + GV + S +F R D L PG P + + D +R V + W P Sbjct: 18600 YEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYD 18657 Query: 410 TESPVMGYFVDRCEVGTNNWVQCNDAP-VKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468 +PV GY V+ E + W C ++ ++ VT L E Y FR+ A+NS G+ P Sbjct: 18658 GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEP 18717 Query: 469 SRVSDAVAALDPL---------DLRRLQA----------VHLEGEKEIAIYQDDLEG--- 506 + + +V A + + DLR++ V ++G E + + EG Sbjct: 18718 ATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18777 Query: 507 -DAQV--------------------------------------------PGPPTGVHASE 521 AQ+ P P + E Sbjct: 18778 DRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18837 Query: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++ V LSWEPP G + Y +EK ++ + + + + +L EG S Sbjct: 18838 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT--FRIENLQEGCS 18895 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE-- 638 Y FRVL++N +G+ P+E T P++ V+ P PGRV T+ + ++W++P+ + Sbjct: 18896 YYFRVLASNEYGIGLPAETTEPVK---VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGG 18952 Query: 639 EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ- 697 + GY V+ G+ W C + + GLT GE+Y+FRV AVN G S+ Q Sbjct: 18953 SKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQL 19010 Query: 698 ----ESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 + I+++ ++ +P H + + L VP + + D + + Sbjct: 19011 GVPVIARDIEIKPSVELPFHTFNVKARE------QLKIDVPFKGRPQATVNWRKDGQTL- 19063 Query: 754 HKNWHEVNSSPSKP-TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE 812 K VN S SK T L++ ++ + +++ N AG S + Sbjct: 19064 -KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG-------SITVPITIIVLDR 19115 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872 PGP + EV S+ + W P Y G +S Y V+ +E + W V+Q A + Sbjct: 19116 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSI 19174 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLVEARPGTKEI----------- 916 K+ L G Y FRV A N G S++S P PGT ++ Sbjct: 19175 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVT 19234 Query: 917 -SAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958 V++ G+ +G+ E + S W K+ + + D + K+ Sbjct: 19235 WQVPVNDGGSRVIGYHL-EYKERSSILWSKANKILIADTQMKV 19276 Score = 171 bits (434), Expect = 4e-42 Identities = 161/542 (29%), Positives = 240/542 (44%), Gaps = 50/542 (9%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DPL G P +P L + + + + WK P + SP+ GY +++ ++ + N Sbjct: 8918 DPL--GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8975 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 + V L E + Y FRV+AVN G S PS + V D + + + G+ Sbjct: 8976 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT 9035 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 + + A V G P + E S+N V+ E PT D L I K V Sbjct: 9036 IKVKAGEPVHIPADVTGLP--MPKIEWSKNETVI--EKPT----DALQ--ITKEEV---- 9081 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PS 613 R A+T + P+ + E K + V ++NR G S + V V PS Sbjct: 9082 -SRSEAKTELSIPK----AVREDKG-TYTVTASNRLG--------SVFRNVHVEVYDRPS 9127 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL--WEPCNHKPIGYNRF 669 P + + S + WD P ++ Y +D A WE + + R+ Sbjct: 9128 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAV-EKRY 9186 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 + L QY FRV+AVN G+S+ +SD + +Q +P P +L SM + Sbjct: 9187 GIWKLIPNGQYEFRVRAVNKYGISDEC-KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLV 9245 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSP-----SKPTILTVDGLTEGSLYEFK 784 W P +GGSPI GY+L+KRE W V+ +P K V L EG Y+F+ Sbjct: 9246 SWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFR 9305 Query: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844 A+N AGIG PS+PS+ P PGP + +S+ + WK P G SP+ Sbjct: 9306 AMAINAAGIGPPSEPSDPEVAGDPIFP-PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPI 9364 Query: 845 SGYFVDFREEDAGEWITVNQ----TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 GY V+ +EE +W VN+ TT V +L++ + Y FRV+AVN G +PSD Sbjct: 9365 KGYIVEMQEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEPSD 9422 Query: 901 TS 902 T+ Sbjct: 9423 TT 9424 Score = 171 bits (433), Expect = 5e-42 Identities = 165/648 (25%), Positives = 245/648 (37%), Gaps = 83/648 (12%) Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL--LKESKWTKMFFGEGQA 338 L+ GV + G+T+ L+ + P P W +D L S K+ + Sbjct: 11833 LKLSGVLTVKAGDTIRLEAGVRGKPF-----PEVAWTKDKDATDLTRSPRVKIDTRADSS 11887 Query: 339 SLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDY 398 S + + D G Y + + G FV A V PG +L+ D + D Sbjct: 11888 KFSLTKAKRSDGGKYVVTATNTAGS-------FVAYATVNVLDKPGPVRNLKIVDVSSDR 11940 Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 V W PP + Y +++CE W A V VT L EG YIFRVR Sbjct: 11941 CTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRLIEGNEYIFRVR 11999 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVH 518 A N G P+ +A + PG P Sbjct: 12000 AENKIGTGPPTESKPVIA----------------------------KTKYDKPGRPDPPE 12031 Query: 519 ASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLME 577 +++S+ + + W PP GK YF+EK S W VN ++A+ R V +L+ Sbjct: 12032 VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN-KSAIPERRMKVQNLLP 12090 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 Y FRV + N G+ EPS + P+ A+D P P TK S+ + W +P + Sbjct: 12091 DHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVY 12150 Query: 638 E--EDLLGYYVD-----CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 + ++GY V+ + W+ CN + F V L ++Y FRV A N Sbjct: 12151 DGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ 12210 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 VG+ ++ + IK + L P ++ K+ G PI + + + Sbjct: 12211 VGIGRPAELKEAIKPKEILEPPEIDLDASMR-----------KLVIVRAGCPIRLFAIVR 12259 Query: 750 -REVHHKNWHEVN----------SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 R W +V L + T ++ + VN AG Sbjct: 12260 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG------ 12313 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + PGP DL +V TS + W P G S V+ Y V+ RE D Sbjct: 12314 -EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKT 12372 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 W TV + V++L G Y FRV AVN G G P+D +PVL Sbjct: 12373 WSTVTPEVKKTSF-HVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVL 12419 Score = 171 bits (433), Expect = 5e-42 Identities = 160/655 (24%), Positives = 271/655 (41%), Gaps = 62/655 (9%) Query: 364 SDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC 422 +++ L + ADP+ V P P + D R+ V ++W P S ++ Y V+ Sbjct: 16739 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16798 Query: 423 EVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + W +C A VK + +T L +G Y+FRV AVN G S P ++ + A D + Sbjct: 16799 AKHSEKWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV- 16855 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL 542 + + + + Y + D ++ P +G R ++W Sbjct: 16856 ------IEPDVKPAFSSYSVQVGQDLKIEVPISG-------RPKPTITWT---------- 16892 Query: 543 MYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 K + R+N ++ ++ + + + + AN G + T+ Sbjct: 16893 -----KDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-----QKTAS 16942 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCN 660 I+ + G V + S+ + W+ P + + Y V T +W+ + Sbjct: 16943 IEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 17002 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 + V L TG +Y FR+ A N G S + ESD I Q P P Sbjct: 17003 -ATVARTTLKVTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPGPPGTPFAT 17060 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 SM + W P +GGSP++GY+L+++E + W +VN + T L EG Sbjct: 17061 AISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIE 17120 Query: 781 YEFKIAAVNLAGIGEPSDPSEHF----KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 YEF++ A N+ G+G+ S SE + C+ PEP V+ + + W P Sbjct: 17121 YEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEP--------IMVKRNEITLQWTKP 17172 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-V 895 VY G S ++GY V+ R+ G W+ + T VS L + + Y FRV A NA G + Sbjct: 17173 VYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAI 17232 Query: 896 GKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYE 948 KPSD++ P+ + IS + I + +A W + + Sbjct: 17233 SKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDK 17292 Query: 949 EISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EI + R +I+ + L +K+ + D G Y + S+ G S SF ++ + L+R Sbjct: 17293 EIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG-SKSFPVNVKVLDR 17346 Score = 170 bits (431), Expect = 8e-42 Identities = 168/685 (24%), Positives = 281/685 (41%), Gaps = 86/685 (12%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R +P W +D LK++ + L +KDD G YT+ + G + Sbjct: 17962 PVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 18021 Query: 365 DHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 + + V + PG P+ ++ + + D+V+++W+PP T + Y V++ + Sbjct: 18022 TENLSVIVLEK-------PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 18074 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDL 483 T W + A V +T L G Y FR+ A N G S P Sbjct: 18075 TTTTTWHMVS-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP--------------- 18118 Query: 484 RRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM 543 L+ + I Y + PGPP + IS++ +++ W P G ++ Sbjct: 18119 -------LDSKAVIVQYP------FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKII 18165 Query: 544 -YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 Y +E+ S W ++N +T ++ ++ L EG Y F+V + N G+ +PS+++ Sbjct: 18166 GYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSEC 18224 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCN 660 A+D P P ++ +RN +V ++W +P ++ + GY V+ W + Sbjct: 18225 FVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18281 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPS----HPY 715 + F V GL ++Y FRV A NA G SE S S I + + P+ Y Sbjct: 18282 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18341 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWH-EVNSSPSKPTILTV 772 ++ G + L + G PI + + D +E+ E+ S+ K T++ Sbjct: 18342 KDVIVVHAGETFVLEADI----RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVK 18397 Query: 773 DGL-TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 D + T+G Y K++ V G S P + PGP L V Sbjct: 18398 DCIRTDGGQYILKLSNVG----GTKSIP-----ITVKVLDRPGPPEGPLKVTGVTAEKCY 18448 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W P+ G + +S Y ++ RE W V+ A Y KV+ L G Y+FRV AV Sbjct: 18449 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY-KVTKLLPGNEYIFRVMAV 18507 Query: 891 NANGVGKPSDTS-----EPVLVEARPGTKEISA------------GVDEQGNIYLGFDCQ 933 N G+G+P ++ P P T E+SA VD+ G G+ Sbjct: 18508 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-IL 18566 Query: 934 EMTDASQFTWCKSYEEISDDERFKI 958 E D W K ++ D R ++ Sbjct: 18567 EKRDKEGVRWTKCNKKTLTDLRLRV 18591 Score = 169 bits (429), Expect = 1e-41 Identities = 139/511 (27%), Positives = 223/511 (43%), Gaps = 34/511 (6%) Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +YIFRV+AVN G+ E ESD + + A P P + +SMT+ W P Sbjct: 20661 GNEYIFRVRAVNKYGIGE-PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIA 20719 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 GGS I GY+L+KR+ W +V + T V GLTE S Y++++ AVN AG G Sbjct: 20720 DGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPF 20779 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S+PSE +K A + PGP + + +S+ + W PVY G S V+GY V+ R+ + Sbjct: 20780 SEPSEFYKA-ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE 20838 Query: 857 GEWITVNQ--TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTK 914 EW TV+ Y+ VS+L+ G Y FRV AVN G G+P + +EPV + Sbjct: 20839 EEWTTVSTKGEVRTTEYV-VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 20897 Query: 915 EISAGVDEQGNIY--LGFDCQEM-----TDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 EI V + ++ G D Q + TW K + + D R+ IE S L Sbjct: 20898 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 20957 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSN-EIKN------------P 1014 + + D G Y +++ + G S + + L+ A ++K+ P Sbjct: 20958 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPP 21017 Query: 1015 TIPLKSELAYEIFDK--GRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 I S + + +K R W H S++ I D R+ + GI Sbjct: 21018 LIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI--DLSEKTPFFFRVLAENEIGI 21075 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 E ++ I D K + +I K + + + ++G Sbjct: 21076 GEPCETTEPVK-AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGE 21134 Query: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKW 1163 + H +++ CE+ +V+ K+++V ++ Sbjct: 21135 QTWSHAGISKTCEI----EVSQLKEQSVLEF 21161 Score = 169 bits (429), Expect = 1e-41 Identities = 160/636 (25%), Positives = 264/636 (41%), Gaps = 66/636 (10%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P + +P W +D + LKES++ + E + +LS + K+ G YT+ Sbjct: 21211 LELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV------ 21264 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 + D++ + G P P ++ + D VI++W P + Y ++ Sbjct: 21265 -ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21323 Query: 421 RCEVGTNNW-VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD 479 + E NW + C+ K P L + Y FRVRA N G+S+P S VA Sbjct: 21324 KRETSQTNWKMVCSSVARTTFKVP--NLVKDAEYQFRVRAENRYGVSQPLVSSIIVA--- 21378 Query: 480 PLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK 539 + ++PGPP ++ + + L+W+ P G Sbjct: 21379 -------------------------KHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGG 21413 Query: 540 DPLMYF-IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSE 598 + F +EK S WQ+VN + + Y L+EG Y FRV + N GLS PS+ Sbjct: 21414 SEVTGFHVEKKERNSILWQKVNT-SPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSD 21472 Query: 599 ITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLW 656 + A P P + +R T + ++W+ P + ++GY ++ G W Sbjct: 21473 PSKFTLAVSPVDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIE-KRQGNERW 21528 Query: 657 EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPY 715 CN + ++ V GL+ G++Y FR+ A NAVG +S SQ S +I + P + Sbjct: 21529 VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEF 21588 Query: 716 GITLLNCDGHSMTLG--WKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILT 771 G DG + G ++ G P+ + ++ D E+ + E+ T L Sbjct: 21589 GPEYF--DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS-TSLF 21645 Query: 772 VDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 V T + + A N +G S + + PG + F + + Sbjct: 21646 VRDATRDHRGVYTVEAKNASG-------SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W AP+ G +P++ Y ++ RE W + A Y + L G Y FRV AV Sbjct: 21699 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSAV 21757 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNI 926 N GVG+P D S+PV+ + + T + G+ E NI Sbjct: 21758 NKFGVGRPLD-SDPVVAQIQ-YTVPDAPGIPEPSNI 21791 Score = 169 bits (427), Expect = 2e-41 Identities = 159/618 (25%), Positives = 253/618 (40%), Gaps = 50/618 (8%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK 441 AP P L D + V + W P S + GY ++ G++ W VK + Sbjct: 14592 APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITT--VKGLE 14649 Query: 442 YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V L EG Y F+V AVNSAG S P R S V + L L + + IA Sbjct: 14650 CVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAG 14708 Query: 502 DDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNA 561 D+++ + V G P ++W+ +G L QRVN Sbjct: 14709 DNIKVEIPVLGRPKPT-----------VTWK----KGDQILK-----------QTQRVNF 14742 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +T S + + + S + + + N G E ++ + IQ D+ P+ P + Sbjct: 14743 ETTATSTILNINECVRSDSGPYPLTARNIVG--EVGDVIT-IQVHDIPGPPTGP--IKFD 14797 Query: 622 RNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 + V WD P+++ + Y V+ + W I + LTTG + Sbjct: 14798 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLE 14856 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y FRVKA N G+ + ++ VP P + SMT+ W P GG Sbjct: 14857 YQFRVKAQNRYGVGPGITSACIV-ANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGG 14915 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPILGY+++++E + W V+ + I GLT+G YEF++ A N+AG +PS P Sbjct: 14916 SPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKP 14975 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 SE P PG L + ++ + W P Y+G ++ Y V+ R+ G W Sbjct: 14976 SEPMLALDPIDP-PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW 15031 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPVLVEARPGTKEISA 918 + N + VS L + Y FRV A NA G + PS+ S+ + +I Sbjct: 15032 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 15091 Query: 919 GVDEQGNIYL--GFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 V + + L G + D S W K +E+ + +I+ + L K+ Sbjct: 15092 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKD 15151 Query: 972 PDKEDLGTYSVSVSDTDG 989 + D G Y+++ ++ G Sbjct: 15152 STRRDSGAYTLTATNPGG 15169 Score = 168 bits (426), Expect = 3e-41 Identities = 145/581 (24%), Positives = 244/581 (41%), Gaps = 63/581 (10%) Query: 335 EGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDA 394 +G++ L + D GLY +++ + G++ + V D PG P++ D Sbjct: 8389 KGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDI 8441 Query: 395 NRDYVIVTWKPPNTTTESPVMGYFVDRCE--VGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 + V+ W+PP S ++ Y +++ + + W+ + ++ CKY VT L EG+ Sbjct: 8442 RKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCKYSVTKLIEGKE 8500 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y+FRVRA N G P VS + A DP G P Sbjct: 8501 YLFRVRAENRFGPGPPC-VSKPLVAKDPF------------------------GPPDAPD 8535 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +++ N +++ W P G L Y++EK V S W RVN ++ + + + V Sbjct: 8536 KPI---VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVN-KSLLNALKANV 8591 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 L+EG +YVFRV + N G + S + P A D + P P + + T++ ++W Sbjct: 8592 DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIELEW 8650 Query: 633 DRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + P +++GY+VD + GTN W C K I ++ V + G Y RV AVNA Sbjct: 8651 EPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAA 8710 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITL-LNCDGHSMTLGWK---VPKFSGGSPILGYY 746 G + V + P P + L ++ G + K +P G P+ Sbjct: 8711 GEGPPGETQPV-----TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8765 Query: 747 LDKREVH-HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 K E K+ +++ +K ++ D L + + I A N G S+ Sbjct: 8766 WTKEEGELDKDRVVIDNVGTKSELIIKDALRKDH-GRYVITATNSCG-------SKFAAA 8817 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 PGP DL ++ W P G S ++G+ ++ ++ W +T Sbjct: 8818 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET 8877 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 + ++ L +G+ Y FRV A N G G P + P+L Sbjct: 8878 ERSK--CDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PIL 8915 Score = 167 bits (424), Expect = 5e-41 Identities = 156/610 (25%), Positives = 250/610 (40%), Gaps = 58/610 (9%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P L R +P W + D +LK+++ L+ + + D G Y L +R V Sbjct: 14716 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL--TARNIVG 14773 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + ++ D + G P P+ + + D+V +W PP P+ Y V+ + Sbjct: 14774 EVGDVITIQVHD--IPGPPTGPIKFD--EVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14829 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + WV+ ++ Y T L G Y FRV+A N G+ P S + A P Sbjct: 14830 DSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPF--- 14884 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 +VPGPP + ++++ + +SW P G P++ Sbjct: 14885 ------------------------KVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILG 14920 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ WQ V ++ V + L +G +Y FRV++ N G S+PS+ + P+ Sbjct: 14921 YHVERKERNGILWQTV-SKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 14979 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNH 661 A D PG+ + T+ +V ++W +P++ + Y V+ W N Sbjct: 14980 LALDPI---DPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 15036 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPYGI--- 717 I N F V GLT Y FRV A NA G +S S+ SD I + + P + Sbjct: 15037 SNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFK 15096 Query: 718 -TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLT 776 T++ G + L V P + + D +E+ E+ + ++ D T Sbjct: 15097 DTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS-T 15153 Query: 777 EGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 + + A N G + F + P P P L EV V+ W P Sbjct: 15154 RRDSGAYTLTATNPGGFAK-----HIFNVKVLDRPGP-PEGPLAVTEVTSEKCVLSWFPP 15207 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 + G + + Y V RE W V + LKV+ L +G Y+FRV AVN GVG Sbjct: 15208 LDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTK-LKVTKLLKGNEYIFRVMAVNKYGVG 15266 Query: 897 KPSDTSEPVL 906 +P + SEPVL Sbjct: 15267 EPLE-SEPVL 15275 Score = 167 bits (424), Expect = 5e-41 Identities = 158/611 (25%), Positives = 256/611 (41%), Gaps = 64/611 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R +P W +D + LK++ + +LS HKDD G Y + + + G S Sbjct: 16884 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 16943 Query: 369 FLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTN 427 + D DP P P+ D + + + ++W PP T + Y V + + T Sbjct: 16944 EIVTLDKPDP-----PKGPVKFD--DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 16996 Query: 428 NWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQ 487 W A V VT L G Y FR+ A N G Q Sbjct: 16997 VW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYG----------------------Q 17033 Query: 488 AVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFI 546 + LE + +A Y + PGPP A+ IS++ +V+ W P G P++ Y + Sbjct: 17034 SFALESDPIVAQYP------YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 17087 Query: 547 EKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ 606 E+ S W +VN +T + ++ +L EG Y FRV + N G+ + S+ + A+ Sbjct: 17088 ERKERNSILWTKVN-KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 17146 Query: 607 DVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPI 664 D P P ++ RN + +QW +P ++ + GY V+ W + + Sbjct: 17147 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 17203 Query: 665 GYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVP----SHPYGITL 719 +F V GLT ++Y FRV A NA G +S+ S + I + + +P + T+ Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17263 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL-TEG 778 + G + L + P + + +E+ E+ ++ K ++ D + +G Sbjct: 17264 VVNAGETFRL--EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17321 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLVMLWKAPV 837 Y + A N+AG S+ F + PGP + V + W P+ Sbjct: 17322 GQYILR--ASNVAG-------SKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPL 17372 Query: 838 YSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G S +S Y V+ RE W V N LKV+ L +G YVFR+ AVN GVG+ Sbjct: 17373 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIMAVNKYGVGE 17431 Query: 898 PSDTSEPVLVE 908 P + S PVL++ Sbjct: 17432 PLE-SAPVLMK 17441 Score = 167 bits (423), Expect = 7e-41 Identities = 161/636 (25%), Positives = 268/636 (42%), Gaps = 74/636 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P+ L + R V + W P T + Y V++ ++ W++ N + + ++ Sbjct: 14988 PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15044 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V+GL E +Y FRV A N+AG IS PS SDA+ D ++ +++ V ++ + + + Sbjct: 15045 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIK-VDVKFKDTVILKA 15103 Query: 502 DD---LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + LE D PPT + W + I+ + S Sbjct: 15104 GEAFRLEADVSGRPPPT-------------MEWSKDGKELEGTAKLEIK---IADFSTNL 15147 Query: 559 VNAQTAVR-SPRYAVFDLMEG--KSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 VN + R S Y + G ++F V +R G E Sbjct: 15148 VNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-------------------- 15187 Query: 616 GRVLASRNTKTSVVVQWDRPKHEEDL-LGYYV-----DCCVAGTNLWEPCNHKPIGYNRF 669 G + + T V+ W P + + +Y+ +A TN+ + + Sbjct: 15188 GPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV-----ASEVQVTKL 15242 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V L G +YIFRV AVN G+ E + V+ V P P + SM + Sbjct: 15243 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNP-YGPPDPPKNPEVTTITKDSMVV 15301 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W P GGS I+ Y +++R+ + W + N V GLTEG YEF+I A N Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15361 Query: 790 LAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848 AGI PS S +K C+ T+ +PGP + + +S+ + W P+Y G S ++GY Sbjct: 15362 AAGISAPSPTSPFYKACD--TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYM 15419 Query: 849 VDFR--EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 V+ EED + +T A Y ++ L + + Y R+ A+N+ G+G+P+ Sbjct: 15420 VEIALPEEDEWQIVTPPAGLKATSY-TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15478 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQ-------EMTDASQFTWCKSYEEISDDERFKIE 959 E R EI D + + + C + A + W + + E D + IE Sbjct: 15479 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15536 Query: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ L + N ++ D G Y ++V ++ G S+FV Sbjct: 15537 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFV 15572 Score = 167 bits (422), Expect = 9e-41 Identities = 157/616 (25%), Positives = 246/616 (39%), Gaps = 58/616 (9%) Query: 309 RVQPRAEWYR---DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSD 365 R P+ W + D+V+ K ++ + A L + +DD G Y+L +V+ G + Sbjct: 12261 RPAPKVTWRKVGIDNVVRKG----QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG--E 12314 Query: 366 HSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVG 425 + F+ VR D PG DL+ D + V+W PP S V Y V++ E Sbjct: 12315 KAVFVNVRVLD-----TPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 12369 Query: 426 TNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 W VK + VT L G Y FRV AVN G P+ V V A DPL Sbjct: 12370 RKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL---- 12424 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 P PP + +E+++N L+W PP G + + Sbjct: 12425 -----------------------SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12461 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQA 605 I R + V+ V L EGK Y FRV + N G+S P E +A Sbjct: 12462 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12521 Query: 606 QDVTVVPS--APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKP 663 ++ + P P ++ K + H D V ++L HK Sbjct: 12522 KEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL---AVHKA 12578 Query: 664 IGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCD 723 + ++ +T + + + A N+ G ++Q+ V+ V A P P+ I+ + D Sbjct: 12579 DSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVV-VMDAPGPPQPPFDIS--DID 12633 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + +L W +P GGS I Y ++K +V +W +S +K T V L G Y F Sbjct: 12634 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIF 12692 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSP 843 ++ A N GI EP + + P + +V + + W P G SP Sbjct: 12693 RVRAENRFGISEPLTSPK--MVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSP 12750 Query: 844 VSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE 903 + GY ++ +E ++ W+ N T + + L +G Y FR+ A+N G PS +E Sbjct: 12751 IIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTE 12810 Query: 904 PVLVEA---RPGTKEI 916 V PG E+ Sbjct: 12811 YVTARMPVDPPGKPEV 12826 Score = 166 bits (420), Expect = 2e-40 Identities = 155/611 (25%), Positives = 243/611 (39%), Gaps = 63/611 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + D L + ++ + SLS + D G Y L+ + G + + Sbjct: 16201 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + A + + WKPP S ++ Y V+R E W Sbjct: 16261 VLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDIINYIVERRETSRLVWTV 16314 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 DA V+ VT L EG Y FR+ AVN G+ P S+ V A +P Sbjct: 16315 V-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEPVVAKNPF---------- 16362 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWE-PPTPRGKDPLMYFIEKSV 550 VP P + ++++ +++ WE P + G + L Y +EK Sbjct: 16363 -----------------VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRD 16405 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 W R + + + R V L+E Y FRV + N GLSEPS ++ +A D Sbjct: 16406 KEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16464 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P P T++SV + W +P ++ ++ GY V+ C W C P G N+ Sbjct: 16465 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCT-PPTGINK 16523 Query: 669 --FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHS 726 V L +Y FR+ A+N G+ E++ I V+ L P + L Sbjct: 16524 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKI---- 16579 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 + +GGS L + R W +V+ I+ V S + Sbjct: 16580 ------INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV----TSSFTSLVLD 16629 Query: 787 AVNLAGIG------EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 VN G E S ++ + P P +L E+ S+ + W+ P+ G Sbjct: 16630 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDG 16689 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 S + Y V+ RE + V N + K+ LQ+G +Y FRV A N G+G P+ Sbjct: 16690 GSKIKNYIVEKREATRKSYAAVVTNCHKNSW-KIDQLQEGCSYYFRVTAENEYGIGLPAQ 16748 Query: 901 TSEPVLVEARP 911 T++P+ V P Sbjct: 16749 TADPIKVAEVP 16759 Score = 165 bits (418), Expect = 3e-40 Identities = 154/563 (27%), Positives = 231/563 (41%), Gaps = 60/563 (10%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ AP P + D + + W PP S V GY V+ E G W + D Sbjct: 10045 DPI---APPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 10101 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 V+ K VTGL EG Y FRVRAVN AGI P V+D + D L Sbjct: 10102 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-------------- 10147 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 DL+ DA V VHA + R +S +PP + + + + + Sbjct: 10148 ----VSPDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPT-----VTWNMNERTLP--- 10194 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 Q +T S + + V+ +L+ N G + + I DV VP Sbjct: 10195 -QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIV------DVLDVPGPV 10247 Query: 616 GRVLASRN-TKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672 G + N T S + W P+ + + Y ++ + W P + N V Sbjct: 10248 GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQ 10306 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWK 732 GL G+ Y FR+ A N++GM + S+ + ++ +TVP P + + +++TL W Sbjct: 10307 GLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN 10366 Query: 733 VPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792 PK+ GGS I+ Y L+ R + + +H+V + TV GL EG YE++++AVN+ G Sbjct: 10367 PPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10426 Query: 793 IGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPV----YSGS-SPVSGY 847 G+PS ++ C+ P P L F RD + + +A YSG P + Sbjct: 10427 QGKPSFCTKPITCKDELAP---PTLHLDF---RDKLTIRVGEAFALTGRYSGKPKPKVSW 10480 Query: 848 FVDFRE--EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 F D + ED I T A +K GK V V N G + Sbjct: 10481 FKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV-----VVENSTGSRKGFCQVN 10535 Query: 906 LVEARPGTKEISAGVDEQGNIYL 928 +V+ RPG DE Y+ Sbjct: 10536 VVD-RPGPPVGPVSFDEVTKDYM 10557 Score = 162 bits (410), Expect = 2e-39 Identities = 182/806 (22%), Positives = 327/806 (40%), Gaps = 96/806 (11%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP I ++ T + +L + G P P ++WY+ G + Q+ KY++ S+ H Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR---KYKMSSDGRTH 24216 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 TL + + +D Y+ +ATN G+V T++ ++++ P Sbjct: 24217 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA----------------------TP 24254 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H EK+ + G T+ L + P P W+ LL+ S+ + Sbjct: 24255 QFHPGYPLKEKY---YGAVGSTLRLHVMYIGRP-----VPAMTWFHGQKLLQNSENITIE 24306 Query: 333 FGEGQASLSFSHLH-KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 E L ++ K G Y +++ + G D + ++D TG P+ ++ Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG----PIVIEA 24362 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 N +++WKPP S + Y V++CE Q + + + + L E Sbjct: 24363 LLKNS--AVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24420 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 Y FRV A N+ GIS P VS V P + P Sbjct: 24421 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------P 24453 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 G P + ++++ V++W+PP G + Y++EK W V + +R + Sbjct: 24454 GAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE-IRETVF 24512 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-DVTVVPSAPGRVLASRNTK--TS 627 +V +L+EG Y FRV N G SE SEI+ PI + DV + L + N + ++ Sbjct: 24513 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24572 Query: 628 VVVQWDRPKHEEDLLGYYVDCC-VAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 + H + ++ +Y + L GY++ ++ +T + +++V+A Sbjct: 24573 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRA 24632 Query: 687 VNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC-DGHSMTLGWKVPKFSGGSPILGY 745 N G S + S ++V A + +P G+ ++ G +++ K+P P++ + Sbjct: 24633 TNQGG-SVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITW 24689 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + + + ++V + S +++ +G+ + + A N GI + + Sbjct: 24690 QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT-------V 24742 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 E P P + +V S+ + W P G S ++ Y V+ A W+ V Q Sbjct: 24743 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ- 24801 Query: 866 TTANRYLKVSDLQQGKT-YVFRVRAVNANGVGKPSDTSEPVLV-EARPGTKEISAGVDEQ 923 RY ++ GKT Y FRV A N G+ KPS+ SEP + E + VDE Sbjct: 24802 ARETRYTVINLF--GKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDET 24859 Query: 924 GNIYLGFDCQEMTDASQFTWCKSYEE 949 + MT AS + + YE+ Sbjct: 24860 REV-------SMTKASHSSTKELYEK 24878 Score = 161 bits (408), Expect = 4e-39 Identities = 155/638 (24%), Positives = 255/638 (39%), Gaps = 72/638 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P +L D + +V + W+ P+ SP + Y V+R G+++W + + +K Y Sbjct: 11729 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHY 11788 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD----PLDLRRLQAVHLEGEKEIA 498 V E + Y FRV+ N G S + + V D LDL+ + ++ I Sbjct: 11789 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIR 11848 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + +A V G P + ++W +K R Sbjct: 11849 L-------EAGVRGKP-----------FPEVAWTK-------------DKDATDLTRSPR 11877 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V T S ++++ + V + N G A V PG V Sbjct: 11878 VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG---------SFVAYATVNVLDKPGPV 11928 Query: 619 LASRNTKTSVV------VQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 RN K V V WD P+ + ++ Y ++ C +W + + V Sbjct: 11929 ---RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTV 11985 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 L G +YIFRV+A N +G ++ VI + P P + MT+ Sbjct: 11986 TR-LIEGNEYIFRVRAENKIGTGPPTESKPVI-AKTKYDKPGRPDPPEVTKVSKEEMTVV 12043 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W P++ GG I GY+L+K+E H W VN S + V L Y+F++ A N Sbjct: 12044 WNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENE 12103 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 GIGEPS PS + P PGP + + S+ + W PVY G +P+ GY V+ Sbjct: 12104 IGIGEPSLPSRPVVAKDPIEP-PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVE 12162 Query: 851 FREEDAGE-----WITVNQTT-TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 R + A W N + V+ L + + Y FRV A N G+G+P++ E Sbjct: 12163 MRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEA 12222 Query: 905 VLVE--ARPGTKEISAGVDEQGNIYLG-----FDCQEMTDASQFTWCKSYEEISDDERFK 957 + + P ++ A + + + G F A + TW K + + + + Sbjct: 12223 IKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQ 12281 Query: 958 IETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 ++ V + L + N ++D G YS+++ + G + FV Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12319 Score = 161 bits (407), Expect = 5e-39 Identities = 157/614 (25%), Positives = 257/614 (41%), Gaps = 62/614 (10%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R P W++D+V LK++ E + L+ ++D G Y +++ + G + Sbjct: 15798 PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + V D G P P+ + + D + ++W PP S + Y V++ + Sbjct: 15858 IETLNVIVLDKP----GPPTGPVKMD--EVTADSITLSWGPPKYDGGSSINNYIVEKRDT 15911 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 T W Q A V L G Y FR+ A N G Sbjct: 15912 STTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAENRYG-------------------- 15950 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLM 543 ++ +L E +A Y +VPGPP + SR+ + + W EP + G + Sbjct: 15951 --KSTYLNSEPTVAQYP------FKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16002 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ S W ++N +T + ++ L EG Y FRV + N G+ +PS+++ Sbjct: 16003 YHLERKERNSILWVKLN-KTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY 16061 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D P P ++ +RN SV +QW +P ++ + GY V+ W + Sbjct: 16062 VARDPCDPPGRPEAIIVTRN---SVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 16118 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGM-SENSQESDVIKVQAALTVP----SHPYG 716 I F V GL +Y FRV A NA G+ SE S+ + I + + P Y Sbjct: 16119 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYK 16178 Query: 717 ITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774 T++ G S +KV G PI + + +E+ + E+ S+ ++ D Sbjct: 16179 DTIVVHAGES----FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDA 16234 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 + S + + A N+AG + S + P P P + V + WK Sbjct: 16235 VRVDS-GNYILKAKNVAG-----ERSVTVNVKVLDRPGP-PEGPVVISGVTAEKCTLAWK 16287 Query: 835 APVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG 894 P+ G S + Y V+ RE W TV KV+ L +G Y FR+ AVN G Sbjct: 16288 PPLQDGGSDIINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 16346 Query: 895 VGKPSDTSEPVLVE 908 VG+P + SEPV+ + Sbjct: 16347 VGEPLE-SEPVVAK 16359 Score = 160 bits (406), Expect = 6e-39 Identities = 164/646 (25%), Positives = 251/646 (38%), Gaps = 84/646 (13%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 EGE +++ P P W++D +K S M A L + D Sbjct: 8028 EGEKLSIPVPFRAVP-----VPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G+YT+ + ++ G + S + V G PG D++ D + +TW+PP Sbjct: 8083 GIYTITLENKLGSATASI-------NVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDG 8135 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 +P++ Y ++R E G ++ K+ + V L Y FRV+AVN G Sbjct: 8136 GTPILHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIE 8194 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 + + V A DP Q P PP V + + ++ Sbjct: 8195 LKNPVIAQDP---------------------------KQPPDPPVDVEVHNPTAEAMTIT 8227 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W+PP G +M Y IEK G W+R N + V Y L EGK Y FRV + N Sbjct: 8228 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCN-EHLVPILTYTAKGLEEGKEYQFRVRAEN 8286 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVL------------ASRNTKTSVVVQWDR--- 634 G+SEPS T P +A D P R AS + + W + Sbjct: 8287 AAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDEN 8346 Query: 635 ---PKHEEDLLGYYVDCCVAGTNLWEP----------CNHKPIGYNRFVVHGLTTGEQYI 681 P+ + V EP ++ G ++ V + + Sbjct: 8347 VIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGL 8406 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSP 741 + +K N G+++ V L P P + S+ W+ P GGS Sbjct: 8407 YMIKVENDHGIAKAPCTVSV------LDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSE 8460 Query: 742 ILGYYLDKRE--VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 I+ Y L+K++ W V S+ + +V L EG Y F++ A N G G P Sbjct: 8461 IINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVS 8519 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCE-VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + P+ A D E V S+++ W P +G SP+ GY+++ RE ++ Sbjct: 8520 KPLVAKDPFGPPD---APDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTH 8575 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 W VN++ V L +G TYVFRV A NA G GK S S+P Sbjct: 8576 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 8621 Score = 158 bits (399), Expect = 4e-38 Identities = 128/444 (28%), Positives = 198/444 (44%), Gaps = 35/444 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 P P + +I+++ V L+WEPP G PL Y +EK V +W +V V Sbjct: 7116 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV--MDFVTDLE 7173 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V DL++GK Y+F+V + N+ G EP+ + P+ VP P V T S+ Sbjct: 7174 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 7233 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + WD PK++ + GY V+ C G++ W C +P+ + V GL G+ Y +RVKA+ Sbjct: 7234 LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPVAETKMEVTGLEEGKWYAYRVKAL 7292 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV--PKFSGGSPILGY 745 N G S+ S+ ++ I+ P + LL G ++ G K+ P G P Sbjct: 7293 NRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL--AGLTVKAGTKIELPATVTGKPEPKI 7350 Query: 746 YLDKREVHHKNWHE--VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 K ++ K + + P K T+ VD + I AVN+ G Sbjct: 7351 TWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGTYIIEAVNVCGRATA------- 7402 Query: 804 KCEAWTMPEPGP--AYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWIT 861 E + +PGP A+D+T +V + S ++ W P G S ++ Y V+ R D+ W Sbjct: 7403 VVEVNVLDKPGPPAAFDIT--DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 7460 Query: 862 VNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVD 921 ++ T + K + L K Y+FRV A N GVG+P V+A P T + D Sbjct: 7461 LSSTVKDTNF-KATKLIPNKEYIFRVAAENMYGVGEP--------VQASPITAKYQ--FD 7509 Query: 922 EQGNIYLGFDCQEMTDASQFTWCK 945 G DA TWC+ Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCE 7533 Score = 157 bits (397), Expect = 7e-38 Identities = 168/638 (26%), Positives = 259/638 (40%), Gaps = 70/638 (10%) Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V+ A+P P P + D ++ + W+ P S V+GY V+ GT W Sbjct: 17835 VKAAEP-----PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSI 17889 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 ++ K+C VTGL G+ Y FRV+A N G S P + V A D L ++ L Sbjct: 17890 VAES--KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD---LTIQPSLKL 17944 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVV 551 +DL+ + V G P +SW + +PL Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPN-----------ISWV----KDGEPLK-------- 17981 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF---RVLSANRHGLSEPSEITSPIQAQDV 608 RVN + S V + EG F V + N G + +E S I V Sbjct: 17982 ---QTTRVNVEETATS---TVLHIKEGNKDDFGKYTVTATNSAGTA--TENLSVI----V 18029 Query: 609 TVVPSAP-GRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIG 665 P P G V + VV+ W+ P + + Y V+ T W + + Sbjct: 18030 LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS-ATVA 18088 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 + L TG +Y FR+ A N G S VI VQ P P + + Sbjct: 18089 RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI-VQYPFKEPGPPGTPFVTSISKD 18147 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 M + W P GG+ I+GY+L+++E + W ++N +P + T GL EG YEFK+ Sbjct: 18148 QMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKV 18207 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 +A N+ GIG+PS SE F P P + + ++ + WK P Y G S ++ Sbjct: 18208 SAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV----ITRNNVTLKWKKPAYDGGSKIT 18263 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEP 904 GY V+ ++ G W+ + T VS L + + Y FRV A NA G +PSD+S Sbjct: 18264 GYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSG- 18322 Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEM---------TDASQFTWCKSYEEISDD-E 954 + AR +A +D + + E W K +E+ + Sbjct: 18323 -AITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAA 18381 Query: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 R +I++ + L +K+ + D G Y + +S+ G S Sbjct: 18382 RMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18419 Score = 151 bits (382), Expect = 4e-36 Identities = 175/732 (23%), Positives = 295/732 (40%), Gaps = 58/732 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP +I + V+ WEPP G ++ Y +EK + + + +R + Sbjct: 8430 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8489 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y+V L+EGK Y+FRV + NR G P ++ P+ A+D P AP + + T S++ Sbjct: 8490 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8548 Query: 630 VQWDRPK-HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 V+W+ PK + +LGY+++ + W N + + V GL G Y+FRV A N Sbjct: 8549 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8608 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 A G + S SD ++ P P + + ++ L W+ P F+GG I+GY++D Sbjct: 8609 AAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVD 8667 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 K+ V W K TV + EG+ Y+ +++AVN AG G P + E Sbjct: 8668 KQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-- 8725 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWK-----APVYSGSSPVSGYFVDFREEDAGEWITVN 863 P+ PA +L V+ +M K A V P + + E D + N Sbjct: 8726 --PQEPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN 8782 Query: 864 QTTTANRYLKVSDLQQGKTYV----------FRVRAVNANGVGKPSDTSEPVLVEARPGT 913 T + +K + + YV F V V P +PV+ + Sbjct: 8783 VGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL 8842 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPD 973 S D+ G+ GF E DA TW + E ER K + G L+ + Sbjct: 8843 LNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIE----TERSKCDITG-----LLEGQE 8892 Query: 974 KEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVR 1033 + + V + G P E+ ++A+ + + PT P L Y K + Sbjct: 8893 YK----FRVIAKNKFGCG-----PPVEIGPILAV-DPLGPPTSP--ERLTYTERTKSTIT 8940 Query: 1034 F-WLQAEHLSPDASYRFIINDREVSDSEIHRIK---CDKATGIIEMVMDRFSIENEGTYT 1089 W + +II R + R+ C + ++E + + E Sbjct: 8941 LDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAV 9000 Query: 1090 VQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLV 1149 +I + + ++V+ D ++ R + ++ + E +H + + + Sbjct: 9001 NEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA---GEPVH--IPADVTGLPM 9055 Query: 1150 CKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQD 1209 K+ +K ETV + D L T+ + EL IPK ++D G Y T + G Sbjct: 9056 PKIEWSKNETVIE-KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9114 Query: 1210 VSILEIAGKVYD 1221 + + +VYD Sbjct: 9115 FRNVHV--EVYD 9124 Score = 151 bits (382), Expect = 4e-36 Identities = 151/584 (25%), Positives = 239/584 (40%), Gaps = 82/584 (14%) Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPP 406 + D G Y + + G +A + V D PG +DL+ NR ++ W P Sbjct: 8796 RKDHGRYVITATNSCGSKFAAARVEVFDV-------PGPVLDLKPVVTNRKMCLLNWSDP 8848 Query: 407 NTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGIS 466 S + G+ ++R + + W Q + C +TGL EG+ Y FRV A N G Sbjct: 8849 EDDGGSEITGFIIERKDAKMHTWRQPIETERSKC--DITGLLEGQEYKFRVIAKNKFGCG 8906 Query: 467 RPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG---VHASEIS 523 P + + A+DPL GPPT + +E + Sbjct: 8907 PPVEIG-PILAVDPL------------------------------GPPTSPERLTYTERT 8935 Query: 524 RNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYV 582 ++ + L W+ P G P+ Y IEK ++RVN + + + V +L E + Y Sbjct: 8936 KSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLC-PTTSFLVENLDEHQMYE 8994 Query: 583 FRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH-EEDL 641 FRV + N G SEPS + + QD V P+ R+ +T + V+ P H D+ Sbjct: 8995 FRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDT---IKVKAGEPVHIPADV 9050 Query: 642 LGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------------QYIFRVKAV 687 G + N E KP + ++ E + + V A Sbjct: 9051 TGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 9108 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYL 747 N +G + +V PS P + + + S L W P +GGS I Y + Sbjct: 9109 NRLGSVFRNVHVEV------YDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9162 Query: 748 DKREVHHK--NWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 DKR+ K W EV ++ + + L YEF++ AVN GI + + Sbjct: 9163 DKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9221 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 + + +P P P + + LV W P+ +G SP++GY+++ REE + W V++ Sbjct: 9222 DPYRLPGP-PGKPKVLARTKGSMLVS-WTPPLDNGGSPITGYWLEKREEGSPYWSRVSRA 9279 Query: 866 TTANRYLK-----VSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 LK V L +G Y FR A+NA G+G PS+ S+P Sbjct: 9280 PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9323 Score = 150 bits (379), Expect = 9e-36 Identities = 109/444 (24%), Positives = 202/444 (45%), Gaps = 39/444 (8%) Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 T + + + +G ++++ N+HG +E I + + V PG V Sbjct: 6675 TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF-----INLKVIDV----PGPVRNLE 6725 Query: 623 NTKT---SVVVQWDRPKHE--EDLLGYYVD-------CCVAGTNLWEPCNHKPIGYNRFV 670 T+T V + W+ P + ++GY V+ V T+ E C F Sbjct: 6726 VTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE--------FT 6777 Query: 671 VHGLTTGE-QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V GL G +Y+FRV A N VG E + + ++ ++ VP P +T+ + + ++L Sbjct: 6778 VTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSL 6837 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W+ P++ GG+ I Y ++ R+ W + ++ TV + EG Y F++ A N Sbjct: 6838 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQN 6897 Query: 790 LAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849 G+G+PS + K A + P P +LT + +S+ + W+ P+ G SP+ GY + Sbjct: 6898 RIGVGKPSAATPFVKV-ADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6956 Query: 850 DFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA 909 + EE WI N KV+ L++G Y++RV A N GV PS+ P+ + Sbjct: 6957 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 7016 Query: 910 R--PGTKEISAGVDEQGNIYLGFDCQEMTDASQF-----TWCKSYEEISDDERFKIETVG 962 T ++SA D + + + ++ + TWC + + +R K++T+ Sbjct: 7017 AFVEPTMDLSAFKDGL-EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7075 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSD 986 +++L + ++ D G Y++ + + Sbjct: 7076 AYAELVISPSERSDKGIYTLKLEN 7099 Score = 150 bits (378), Expect = 1e-35 Identities = 138/520 (26%), Positives = 208/520 (40%), Gaps = 88/520 (16%) Query: 375 ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD--RCEVGTNNWVQC 432 +DPL P P L+ + ++ + W PP + + GY E + W + Sbjct: 12421 SDPL--SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEY 12478 Query: 433 NDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAA----LDPLDLRRLQ- 487 + VK VTGL EG+ Y FRV A N+ G+S P A L P L Q Sbjct: 12479 S--VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI 12536 Query: 488 -------------------------------------AVHLEGEKEIAIYQDDLEGDA-- 508 AVH I I +D D+ Sbjct: 12537 TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12596 Query: 509 ---------------------QVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YF 545 PGPP S+I + LSW P G + Y Sbjct: 12597 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYI 12656 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP-IQ 604 +EK V G W V A +V V L+ G+ Y+FRV + NR G+SEP +TSP + Sbjct: 12657 VEKCDVSRGDW--VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMV 12712 Query: 605 AQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHK 662 AQ VPS P ++ K + V WDRP + ++GY ++ + LW N Sbjct: 12713 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12772 Query: 663 PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC 722 + + GL G +Y FR+ A+N G S S+ ++ + + + P P +++ Sbjct: 12773 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKP---EVIDV 12829 Query: 723 DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTVDGLTEGSL 780 +++L W PK GGS I+GY+++ ++ W N++P + T GL E + Sbjct: 12830 TKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQ 12889 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLT 820 Y+F+ A I PS+PS+ A +P P DL+ Sbjct: 12890 YQFRAIARTAVNISPPSEPSDPVTILAENVP---PRIDLS 12926 Score = 149 bits (376), Expect = 2e-35 Identities = 199/866 (22%), Positives = 327/866 (37%), Gaps = 118/866 (13%) Query: 150 ISRAPEIL--VRLRSHTVWER-MSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 I APEI V LR+ + + V++ +G P P V W KD + A +Y IE Sbjct: 20893 ILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA---RYSIE 20949 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 + L I + +DT Y N +G P Sbjct: 20950 NTDSSSLLTIPQVTRNDTGKYILTIENG----------------------------VGEP 20981 Query: 267 LSSMIPYTHFDVQFL-EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKE 325 SS + D +K V G TVTL + P + P + + + Sbjct: 20982 KSSTVSVKVLDTPAACQKLQVKHVSRG-TVTL---LWDPPLIDGGSPIINYVIEKRDATK 21037 Query: 326 SKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGA 385 W+ + +S SF + ++ + R+++ + +P+ A Sbjct: 21038 RTWSVV--SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEP---CETTEPVKAAEVPA 21092 Query: 386 PM-DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPV 444 P+ DL D+ + VI++W P+ S + Y V+R G W + K C+ V Sbjct: 21093 PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGIS--KTCEIEV 21150 Query: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504 + L E FRV A N G+S P + P+ ++ L I + DL Sbjct: 21151 SQLKEQSVLEFRVFAKNEKGLSDP-------VTIGPITVKEL----------IITPEVDL 21193 Query: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTA 564 + +PG V I N + E P P + +++ + Sbjct: 21194 ---SDIPGAQVTVR---IGHN---VHLELPYKGKPKPSISWLKDGL-------------P 21231 Query: 565 VRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ--AQDVTVV----PSAP-GR 617 ++ + F E K + + HG + + + A +TV+ PS P G Sbjct: 21232 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21291 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHK----PIGYNRFVVHG 673 + SV++ WD P ED G + C N K + F V Sbjct: 21292 IRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPN 21348 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 L +Y FRV+A N G+S+ S +I + +P P + N M+L W Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQ-PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDA 21407 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 P + GGS + G++++K+E + W +VN+SP GL EG Y+F++ A N AG+ Sbjct: 21408 PVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21467 Query: 794 GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE 853 PSDPS+ + P P Y +V ++ + W P+ G S + GY ++ R+ Sbjct: 21468 SSPSDPSKFTLAVSPVDPPGTPDY----IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ 21523 Query: 854 EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP----------SDTSE 903 + W+ N T + V+ L G Y FR+ A NA G P D + Sbjct: 21524 GNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV 21582 Query: 904 PVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGD 963 P +VE G + + + G + + TW K EI +I V Sbjct: 21583 PPIVEF--GPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG 21640 Query: 964 HSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L++++ ++ G Y+V + G Sbjct: 21641 STSLFVRDATRDHRGVYTVEAKNASG 21666 Score = 149 bits (376), Expect = 2e-35 Identities = 139/518 (26%), Positives = 220/518 (42%), Gaps = 56/518 (10%) Query: 511 PGPPTG-VHASEISRNYVVLSWEPPTPRG-KDPLMYFIEKSVVGSGSWQRVNAQTAVRSP 568 P P G + +I V +SW PP G D L Y +E+ V +W ++++ VR Sbjct: 23856 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR--VRGT 23913 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ---DVTVVPSAPGRVLASRNTK 625 V L E Y FRV + N+ G+S+P + P+ + + PS P VL TK Sbjct: 23914 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV--TK 23971 Query: 626 TSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFR 683 +SV + W RPK + + GYY++ T+ W N I + V GL +Y FR Sbjct: 23972 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24031 Query: 684 VKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPIL 743 + A N VG+SE S S+ + + PS P + +L+ S+TL W+ P+ GG IL Sbjct: 24032 IIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEIL 24091 Query: 744 GYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 GY+++ R+ W + N K T+ GL E + YEF++ A N G+ P + Sbjct: 24092 GYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSI 24151 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 K + + PG E++D + + G + + R +W Sbjct: 24152 KTKLTSGEAPGIRK-----EMKDVTTKL--------GEAAQLSCQIVGRPLPDIKWYRFG 24198 Query: 864 QTTTANRYLKVSDLQQGKTYVFRV-----------RAVNANGVGKPSDTSEPVLVEARP- 911 + +R K+S G+T+ V + N VG+ +TS +L++A P Sbjct: 24199 KELIQSRKYKMS--SDGRTHTLTVMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQ 24255 Query: 912 -----GTKEISAGVD----EQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVG 962 KE G +Y+G M TW + + + E IE Sbjct: 24256 FHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAM------TWFHGQKLLQNSENITIENTE 24309 Query: 963 DHSKLYLKNPD-KEDLGTYSVSVSDTDGVSSSFVLDPE 999 ++ L +KN K G Y V +S+ G + +LD E Sbjct: 24310 HYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA-ILDVE 24346 Score = 147 bits (371), Expect = 7e-35 Identities = 164/689 (23%), Positives = 272/689 (39%), Gaps = 81/689 (11%) Query: 250 RGDEEPFRSVGLP-----IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 +G +P R +G+P I + S +P+ F+V+ E+ + +G Sbjct: 19002 KGRSDP-RQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKG------------ 19048 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 R Q W +D LKE+ + + SLS K+D G Y L + + G Sbjct: 19049 ----RPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 19104 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + V D PG P ++ + + D + ++W PP + Y V++ E Sbjct: 19105 TVPITIIVLDR-------PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKET 19157 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + W + A V + L G Y FRV A N G S S S VA Sbjct: 19158 TSTTWHIVSQA-VARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA-------- 19208 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 E PGPP +++ ++++W+ P G ++ Sbjct: 19209 --------------------EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIG 19248 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E S W + N + + + V L EG Y +RV + N G+ + S+ P+ Sbjct: 19249 YHLEYKERSSILWSKAN-KILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19307 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D PG+ + T+ SV ++W +P ++ + GY V+ W CN+ Sbjct: 19308 PARDPC---DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19364 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAV-GMSENSQESDVIKVQAALTVPSHPYGITLL 720 I F V LT ++Y FRV A NA +SE S+ + I V+ + P + Sbjct: 19365 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFR 19424 Query: 721 NCDGHSMTLGWKVPKFSGGS--PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 + K+ G P++ + D E+ + E+ S+ + T+LTV Sbjct: 19425 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNH-TLLTVKDCIRR 19483 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 ++ + N+AG S C+ P P PA L + + W P Sbjct: 19484 DTGQYVLTLKNVAG-----TRSVAVNCKVLDKPGP-PAGPLEINGLTAEKCSLSWGRPQE 19537 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G + + Y V+ RE W T+ + KV+ L +G Y+FRV VN GVG+P Sbjct: 19538 DGGADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19596 Query: 899 SDT-----SEPVLVEARPGTKEISAGVDE 922 ++ +P V + P + EI++ E Sbjct: 19597 LESVAIKALDPFTVPSPPTSLEITSVTKE 19625 Score = 144 bits (364), Expect = 5e-34 Identities = 163/681 (23%), Positives = 264/681 (38%), Gaps = 79/681 (11%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P+ RD V LK + +++ D G Y + + G + + Sbjct: 20134 PKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV 20193 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + D + V + W+PP S V Y + + E T W + Sbjct: 20194 VLDRP----GPPTGPVVIS--DITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20247 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 + A V V L G Y FR++A N GIS D +D + Sbjct: 20248 VS-ATVARTMMKVMKLTTGEEYQFRIKAENRFGIS------------DHIDSACVT---- 20290 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550 ++ PGPP+ + ++R + + W P G ++ Y +E Sbjct: 20291 ------------VKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD 20338 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 S WQ+ N + +R+ + V + G Y FRV + N G+ +PS + P+ A D Sbjct: 20339 RNSILWQKAN-KLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC- 20396 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P V + +K SV + W +P + + GY V+ W + + + Sbjct: 20397 --EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20454 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY-GITLLNCDGHSM 727 F++ GLT QY FRV A NAVG N S+V+ + P + L + Sbjct: 20455 FIISGLTQNSQYEFRVFARNAVGSISNP--SEVVGPITCIDSYGGPVIDLPLEYTEVVKY 20512 Query: 728 TLGWKVPKFSGGS----PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG--LTEGSLY 781 G V +G S P + +Y D +E+ V ++ +IL D L G Y Sbjct: 20513 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-Y 20571 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 E K+ N G S + + P P P + F V + +LW+ P G Sbjct: 20572 ELKLR--NAMG-----SASATIRVQILDKPGP-PGGPIEFKTVTAEKITLLWRPPADDGG 20623 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 + ++ Y V+ RE W V++ + + + +G Y+FRVRAVN G+G+P ++ Sbjct: 20624 AKITHYIVEKRETSRVVWSMVSEHLE-ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20682 Query: 902 SEPVLVEA-----RPGTKEI------------SAGVDEQGNIYLGFDCQEMTDASQFTWC 944 V A PG E+ S + + G+ G+ E D W Sbjct: 20683 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY-FLEKRDKKSLGWF 20741 Query: 945 KSYEEISDDERFKIETVGDHS 965 K +E D R K+ + ++S Sbjct: 20742 KVLKETIRDTRQKVTGLTENS 20762 Score = 141 bits (355), Expect = 5e-33 Identities = 122/473 (25%), Positives = 210/473 (44%), Gaps = 49/473 (10%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+ ++ L WEPP G + Y I+K ++ V+++ + S Sbjct: 17744 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTS-- 17801 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V +L EG Y FRV++ N G+ P E ++A + PS PG+V + ++TS Sbjct: 17802 FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP---PSPPGKVTLTDVSQTSAS 17858 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ GT W + VV GL++G++Y FRVKA Sbjct: 17859 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC--NAVVTGLSSGQEYQFRVKAY 17916 Query: 688 NAVGMSEN-----SQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 N G S+ + + +Q +L +P + Y I G + + ++P P Sbjct: 17917 NEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQA----GEDLKI--EIPVIGRPRPN 17970 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 + + D + V + + T+L + + ++ + A N AG +E+ Sbjct: 17971 ISWVKDGEPLKQTTRVNVEETATS-TVLHIKEGNKDDFGKYTVTATNSAGTA-----TEN 18024 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P P P + F EV +V+ W+ P Y+G +S Y V+ R+ W V Sbjct: 18025 LSVIVLEKPGP-PVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMV 18083 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE------ARPGTKEI 916 + T A +K++ L+ G Y FR+ A N G P D S+ V+V+ PGT + Sbjct: 18084 S-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIVQYPFKEPGPPGTPFV 18141 Query: 917 SA------------GVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFK 957 ++ V++ G +G+ E + + W K + D +FK Sbjct: 18142 TSISKDQMLVQWHEPVNDGGTKIIGYHL-EQKEKNSILWVKLNKTPIQDTKFK 18193 Score = 140 bits (353), Expect = 9e-33 Identities = 116/421 (27%), Positives = 187/421 (44%), Gaps = 32/421 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGP + ++I+++ V L W+ P G + Y +EK S+ A T Sbjct: 14496 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS--TATTKCHKCT 14553 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y V L EG Y FRV++ N +G+ EP+E T P++A + PS P + TK++V Sbjct: 14554 YKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLNIMDITKSTVS 14610 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W +PKH+ + GY ++ G++ W + + VV LT GE+Y F+V AV Sbjct: 14611 LAWPKPKHDGGSKITGYVIEAQRKGSDQW--THITTVKGLECVVRNLTEGEEYTFQVMAV 14668 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI---TLLNCDGHSMTLGWKVPKFSGGSPILG 744 N+ G S + VI + + GI ++ G ++ + ++P P + Sbjct: 14669 NSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV--EIPVLGRPKPTVT 14726 Query: 745 YYLDKREVHHKNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 + K + K VN + + TIL ++ + + A N+ G + + Sbjct: 14727 W--KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG-----EVGDVI 14779 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 + +P P P + F EV + W P G P+S Y V+ R+ D+ W+ + Sbjct: 14780 TIQVHDIPGP-PTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14838 Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE------PVLVEARPGTKEIS 917 T Y K + L G Y FRV+A N GVG P TS P V PGT +++ Sbjct: 14839 TTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPFKVPGPPGTPQVT 14896 Query: 918 A 918 A Sbjct: 14897 A 14897 Score = 136 bits (343), Expect = 1e-31 Identities = 112/417 (26%), Positives = 180/417 (43%), Gaps = 28/417 (6%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+++ V L+W+PP G + Y +EK ++ V T Sbjct: 15580 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV--ATNCHKTS 15637 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V L EG SY FRVL+ N +G+ P+E ++A + P PG++ T+ SV Sbjct: 15638 WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASE---RPLPPGKITLMDVTRNSVS 15694 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ G++ W C + + GL GE+Y FRV A Sbjct: 15695 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQ 15752 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI-TLLNCDGHSMTLGWKVPKFSGGSPILGYY 746 N G+S+ Q S + + + P+ T G + + VP +P + ++ Sbjct: 15753 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKV--DVPFIGRPTPAVTWH 15810 Query: 747 LDKREVHHKNWHEVNS-SPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D V K VN+ S ++LT+ + + + N AG + E Sbjct: 15811 KD--NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG-----EAIETLNV 15863 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P P P + EV S+ + W P Y G S ++ Y V+ R+ W V+ Sbjct: 15864 IVLDKPGP-PTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-A 15921 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGV-----GKPSDTSEPVLVEARPGTKEIS 917 T A +K L+ G Y FR+ A N G +P+ P V PGT ++ Sbjct: 15922 TVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15978 Score = 134 bits (337), Expect = 6e-31 Identities = 174/771 (22%), Positives = 294/771 (38%), Gaps = 127/771 (16%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT-LEINRADFDDTATYSA 229 ++L ++G P P+ +W K+G I + A + + HT L I AD D+ TY Sbjct: 23782 IRLTIPIKGKPFPICKWTKEGQDISKRA------MIATSETHTELVIKEADRGDSGTYDL 23835 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 V N G+ + V V IG P S P + D+Q + V++R Sbjct: 23836 VLENKCGKKAVYIKVRV----------------IGSPNSPEGPLEYDDIQ-VRSVRVSWR 23878 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 + + +R P+A WY D ++ + SL L ++ Sbjct: 23879 PPADDGGADILGYILE--RREVPKAAWYTIDSRVRGT------------SLVVKGLKENV 23924 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCH-----DANRDYVIVTWK 404 E + + ++ G+S ++ +P+ P P + + D + V ++W Sbjct: 23925 EYHFRVSAENQFGISKP-----LKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 23979 Query: 405 PPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG 464 P S V GY+++R E T+ WV+ N + Y VTGL Y FR+ A N G Sbjct: 23980 RPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVG 24039 Query: 465 ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISR 524 +S S S+ V DP D P P + IS+ Sbjct: 24040 LSETSPASEPVVCKDPFD---------------------------KPSQPGELEILSISK 24072 Query: 525 NYVVLSWE-PPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF 583 + V L WE P GK+ L Y++E G +W++ N + ++ ++ + L+E Y F Sbjct: 24073 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE-RIKDKQFTIGGLLEATEYEF 24131 Query: 584 RVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG--RVLASRNTKTSVVVQWD-----RPK 636 RV + N GLS P I+ + APG + + TK Q RP Sbjct: 24132 RVFAENETGLSRPRRTAMSIKTK--LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 24189 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY---IFRVKAVNAVGMS 693 D+ Y G L + +K R + T EQ ++ A N VG Sbjct: 24190 --PDIKWYRF-----GKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEV 24242 Query: 694 ENSQESDVIKVQAALTVPSHP--------YGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 E S K+ T HP YG H M +G VP + + Sbjct: 24243 ETSS-----KLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT-------W 24290 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + ++ + + + ++ ++ + + ++K+ N+ G + Sbjct: 24291 FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI-----LDV 24345 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE-EDAGEWITVNQ 864 E P+ P + + S V+ WK P G S ++ Y V+ E ++ EW V+ Sbjct: 24346 EIQDKPDK-PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSS 24404 Query: 865 TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA---RPG 912 + ++ +L + Y FRV A N G+ P + S V++++ +PG Sbjct: 24405 AISVTT-CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG 24454 Score = 121 bits (304), Expect = 4e-27 Identities = 113/424 (26%), Positives = 188/424 (44%), Gaps = 38/424 (8%) Query: 493 GEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVV 551 G+KE I L+ PGPP V EIS++ ++WEPP G P++ Y ++K Sbjct: 13401 GKKEYTIVVKVLD----TPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDA 13456 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV 611 SW V + + S + V +L EGKSY FRV + N +G+ +P E ++A Sbjct: 13457 ERKSWSTVTTECSKTS--FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS----- 13509 Query: 612 PSAPGRVL---ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGY 666 PG V+ +K+S + W +P + ++GY VD + N W+ K + Sbjct: 13510 -QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRV-MKSLSL 13566 Query: 667 NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK---VQAALTVPSHPYGITLLNCD 723 ++ LT G++Y FRV A N G S+ + V + V L + P + L + Sbjct: 13567 -QYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLP-DLCYLAKE 13624 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + L K+P +P + + + + V SS T++ D + ++ Sbjct: 13625 NSNFRL--KIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKY 13681 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG-PAYDLTFCEVRDTSLVMLWKAPVYSGSS 842 I N+AG E + + +PG P + F EV ++ + W P G S Sbjct: 13682 TITLKNVAGTKEGT-------ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGS 13734 Query: 843 PVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 ++ Y ++ R+ +W+T + +V+ L +G Y FRV A N GVG+ S Sbjct: 13735 EITNYILEKRDSVNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGE-GLKS 13792 Query: 903 EPVL 906 EP++ Sbjct: 13793 EPIV 13796 Score = 111 bits (278), Expect = 4e-24 Identities = 93/324 (28%), Positives = 134/324 (41%), Gaps = 41/324 (12%) Query: 152 RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRI-ESNYG 210 +AP LR+ V + + L V G P P+V+WY+ G I A+ KYRI E G Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKGG 24611 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 H L I DD Y ATN G VS A+ L + +P Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-----------------LEVEVPAKIH 24654 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 +P T LE G GE V++K PD P W + L+ + + Sbjct: 24655 LPKT------LEGMGAVHALRGEVVSIKIPFSGKPD-----PVITWQKGQDLIDNNGHYQ 24703 Query: 331 MFFGEGQASLSFSH-LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDL 389 + SL F + + + D G Y + +R G+ + L V D P P + Sbjct: 24704 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADV-------PDPPRGV 24756 Query: 390 QCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFE 449 + D +RD V +TW P + S + Y V++C W++ A + +Y V LF Sbjct: 24757 KVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RETRYTVINLFG 24814 Query: 450 GRSYIFRVRAVNSAGISRPSRVSD 473 SY FRV A N G+S+PS S+ Sbjct: 24815 KTSYQFRVIAENKFGLSKPSEPSE 24838 Score = 95.5 bits (236), Expect = 3e-19 Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 25/408 (6%) Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCN 660 ++ QD P+ P ++ K S V+ W P + + Y V+ C A Sbjct: 24345 VEIQDKPDKPTGP--IVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24402 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 I + LT Y FRV A N G+S+ + S V+ +++ P P T+ Sbjct: 24403 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24462 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 S + WK P GG+ I YYL+KRE W V + + T+ +V L EG Sbjct: 24463 AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLE 24522 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY--DLTFCEVRDTSLVMLWKAPVY 838 YEF++ NL G E S+ SE ++ +P P + +L VR S L V Sbjct: 24523 YEFRVKCENLGGESEWSEISEPITPKS-DVPIQAPHFKEELRNLNVRYQSNATL-VCKVT 24580 Query: 839 SGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG--- 894 P+ ++ +E A G + + L ++ + V++VRA N G Sbjct: 24581 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 24640 Query: 895 ------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYE 948 V P+ P +E G + A E +I + F + TW K + Sbjct: 24641 GTASLEVEVPAKIHLPKTLE---GMGAVHALRGEVVSIKIPFSGK---PDPVITWQKGQD 24694 Query: 949 EISDDERFKIETVGDHSKLYLKN-PDKEDLGTYSVSVSDTDGVSSSFV 995 I ++ +++ + L N +++D G Y V + G+ V Sbjct: 24695 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24742 Score = 77.8 bits (190), Expect = 7e-14 Identities = 113/534 (21%), Positives = 206/534 (38%), Gaps = 93/534 (17%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K+ EI E+FKI G +L + N ED Y+ V D Sbjct: 2855 FECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-VCGNDQ 2913 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 VS++ + P + ++ N + TI + + YE SY++ Sbjct: 2914 VSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYE------------------GISYKW 2955 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + N E+ ++ +++ K T + + F + T+ GKA S ++L + Sbjct: 2956 LKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYV---- 3007 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDV- 1168 E + EF + H + V E+ C+V+ + + +W+KDD Sbjct: 3008 --------EARHIEFRK----HIKDI---KVLEKKRAMFECEVS--EPDITVQWMKDDQE 3050 Query: 1169 LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAM 1227 L T+ + E+ + LLIP D G+Y G +VS ++ + D I ++ Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGRDVRIRSI 3106 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS--EHMRIGGSEEM 1285 + ++V+ E R + D++ +W +I+ E + + Sbjct: 3107 KK-------EVQVI---EKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRI 3156 Query: 1286 AWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGR 1345 + I E + D G+YTF G++ +L ++ + E Q Sbjct: 3157 HRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQELQP------------- 3201 Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVK-VEQAKYVSMT 1404 VT+ GK + G P P++ W+K +Q LS F K + + ++ Sbjct: 3202 --------VTVQSGKPARFCAVISGRPQPKISWYKEEQ--LLSTGFKCKFLHDGQEYTLL 3251 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPA 1458 + ED+ Y+ KN YG ++SV ++P++ P Q P PA Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSV-----EVPEVVSPDQEMPVYPPA 3300 Score = 72.4 bits (176), Expect = 3e-12 Identities = 113/531 (21%), Positives = 199/531 (37%), Gaps = 76/531 (14%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K +E+ +R KI+ +L + + D G Y+V Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVS 3090 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASY-- 1047 + FV + R+ ++ E+ ++ +K R + DA + Sbjct: 3091 TAKLFVEGRDV--RIRSIKKEV-------------QVIEKQRAVVEFEVNEDDVDAHWYK 3135 Query: 1048 -----RFIINDRE--VSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQ 1100 F + +R V + IHR M + + G YT +++ Sbjct: 3136 DGIEINFQVQERHKYVVERRIHR-----------MFISETRQSDAGEYTFVA----GRNR 3180 Query: 1101 SSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETV 1160 SS+ L +A + P + L + + C V + + + Sbjct: 3181 SSVTLYVNA-----------------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPK 3223 Query: 1161 FKWLKDDVLYETETLPNLERGICE--LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218 W K++ L T E LL+ + +D Y K+D G + ++ + Sbjct: 3224 ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283 Query: 1219 VYDDMILAMSRVCGKSA--SPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSS 1274 V + + A +PL+ T EG R QC + ++KV+W KD KI S Sbjct: 3284 VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQC--RVSGTDLKVSWYSKDKKIKPS 3341 Query: 1275 EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFD--GKDNHQRSLDLSG-QAFDEAFAEFQ 1331 R+ E+ L+I E +D+G YTF + G+ + +L L G F+E + Q Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQ 3401 Query: 1332 QFKAAAFAEKNRGRLIGGLPDVV------TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDI 1385 + + + K +G P + + G+T+ V G P PE+ WF N Q I Sbjct: 3402 WHVSLSVSFKKEP--LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLI 3459 Query: 1386 QLSEHFSVKVEQAKYVS-MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ E++ ++ M I SE +G+YS N G T++V Sbjct: 3460 LPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510 Score = 65.9 bits (159), Expect = 3e-10 Identities = 67/248 (27%), Positives = 102/248 (41%), Gaps = 30/248 (12%) Query: 30 DEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRY 89 +EY K A ++SS S R + + L + + R E+ E + R Sbjct: 25877 EEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRS 25936 Query: 90 QSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEER 149 + E R R S ++ + L+R + + D ++ + M+ L ++ T E + Sbjct: 25937 PT-----PERTRPRSPSPVS---SERSLSRFERSARFDIFSRYESMKAALKTQK-TSERK 25987 Query: 150 ----------ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE 199 + AP I +R+RSH V + + VQ PT V+WY +G + E Sbjct: 25988 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG---VELQE 26044 Query: 200 PGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVV--------RRFRG 251 K + GV TLEI DD+ TY AV TN G+ S A + V R Sbjct: 26045 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR 26104 Query: 252 DEEPFRSV 259 DEE RSV Sbjct: 26105 DEEVPRSV 26112 Score = 65.9 bits (159), Expect = 3e-10 Identities = 50/166 (30%), Positives = 76/166 (45%), Gaps = 22/166 (13%) Query: 1262 VNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTF--EIFDGKDNHQRSLDLS 1319 V W ++++SE R G S L I + + +D+G T + +G Q L LS Sbjct: 26696 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26755 Query: 1320 GQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWF 1379 + D A AF + R + I EG+ + TC + G P PE+ WF Sbjct: 26756 KELSD----------APAFISQPRSQ---------NINEGQNVLFTCEISGEPSPEIEWF 26796 Query: 1380 KNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 KN+ I +S + S+ + Y S+ I+ + DSGKY+I KN G Sbjct: 26797 KNNLPISISSNVSISRSRNVY-SLEIRNASVSDSGKYTIKAKNFRG 26841 Score = 63.9 bits (154), Expect = 1e-09 Identities = 61/247 (24%), Positives = 97/247 (39%), Gaps = 22/247 (8%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + +L++ + E +++ G P P + W K+ +I P K RIE G Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L+I+ D+A Y+A A N G+ +T V V + EP R + +P G + I Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAA 1628 Query: 274 THFDVQFLE------KFGVTFRREGETVTLKCTMLVTPDLKRVQPR-------------- 313 + L + G + +E + L + LKR P Sbjct: 1629 PELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTM 1688 Query: 314 -AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372 EW D L+ + +M G SL + + D G+ T R ++ G SA L V Sbjct: 1689 VVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748 Query: 373 RDADPLV 379 +D LV Sbjct: 1749 KDEKSLV 1755 Score = 62.0 bits (149), Expect = 4e-09 Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 123 RDKLDKYAIQQMMEDKLAWERHTFEERI-SRAPEILVRLRSHTVWERMSVKLCFTVQGFP 181 R+ D Y + M + K R T R+ R PE + L + T + +V+ T+ P Sbjct: 25290 REVYDYYCRRTMKKIK----RRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 25345 Query: 182 TPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTN 241 P V WYK G I KY ES+ G++ L IN DD A Y+ VA N +G+ S Sbjct: 25346 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 25405 Query: 242 AAVVV 246 A + V Sbjct: 25406 AKLTV 25410 Score = 61.6 bits (148), Expect = 5e-09 Identities = 73/333 (21%), Positives = 124/333 (37%), Gaps = 48/333 (14%) Query: 76 STQEDEEQENRSRYQSLVA--AYGEAKRQRFLS-ELAHLEEDVHLARSQARDKLDKYAIQ 132 ++Q +E+ RS + L AY + ++ E + +V ++ R+ L Y Sbjct: 26100 ASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26159 Query: 133 QMMEDK-LAWERHTFEERISR-------APEILVRLRSHTVWERMSVKLCFTVQGFPTPV 184 E K A E + EE+ + A IL + RS TV+E S + G P P Sbjct: 26160 ASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT 26219 Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W + G ++ +A ++++ + T EI+ D YS V N+ G+ + Sbjct: 26220 VTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26276 Query: 245 VVRRFRGDEEPFRS----------------------VGLPIGLPLSSMIP---------- 272 +++ R E+ S V P ++ P Sbjct: 26277 TIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEK 26336 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H V K + E K T +V + R + WY+D LKE+ + Sbjct: 26337 VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK-EVTWYKDGKKLKENGHFQFH 26395 Query: 333 FG-EGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 + +G L ++L + D+G Y I GG S Sbjct: 26396 YSADGTYELKINNLTESDQGEYVCEISGEGGTS 26428 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D+VTI G L L V G P+P++IW K D+++ L E S++ K + IK Sbjct: 22683 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY-TGKRATAVIKFCDRS 22741 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ +KN G + + V V V Sbjct: 22742 DSGKYTLTVKNASGTKAVSVMVKV 22765 Score = 59.3 bits (142), Expect = 3e-08 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 24/201 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++L L+ TV + C + G P P + WYK+ L+ K + + +T Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF---KCKFLHDGQEYT 3249 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L + A +D A Y+ A N +G +T+A++ SV +P + +P Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASL-------------SVEVPEVVSPDQEMPV 3296 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + T EG+ +C + T DLK WY D +K S++ +M Sbjct: 3297 --YPPAIITPLQDTVTSEGQPARFQCRVSGT-DLK-----VSWYSKDKKIKPSRFFRMTQ 3348 Query: 334 GEGQASLSFSHLHKDDEGLYT 354 E L + + +DEG YT Sbjct: 3349 FEDTYQLEIAEAYPEDEGTYT 3369 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/337 (21%), Positives = 124/337 (36%), Gaps = 49/337 (14%) Query: 1129 GPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW------LKDDVLYETETLPNLERGI 1182 GP + +H E V+ VCK+ N + T W L++ YE E G+ Sbjct: 25196 GPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEI----TYEDGV 25251 Query: 1183 CELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK----VYDDMILAMSRVCGKSASPL 1238 L + ++K D G Y+ + +D G+D S E+ K VYD + + + Sbjct: 25252 AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTM 25311 Query: 1239 KVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL---QICEPTE 1295 ++L P L + K + + + + + W Q +P + Sbjct: 25312 RLLERPPEFTLPLYNK---------TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25362 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKN-RGRLIGGLPDVV 1354 DK KYTFE D L ++ D+ AE+ + E + + +L L Sbjct: 25363 NDK-KYTFE----SDKGLYQLTINSVTTDDD-AEYTVVARNKYGEDSCKAKLTVTLHPPP 25416 Query: 1355 T----------------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA 1398 T EG+++ V G P P + W K+ Q + L + + E Sbjct: 25417 TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGL 25476 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 Y ++ I+ ED+G Y + N G + V Sbjct: 25477 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513 Score = 58.9 bits (141), Expect = 3e-08 Identities = 104/506 (20%), Positives = 199/506 (39%), Gaps = 98/506 (19%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ T+ ++ W ++ E I D ++ I L +++ +D Y+VS+++ G Sbjct: 6287 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6346 Query: 990 VS----SSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDA 1045 + ++ +++ E+L + PLK E +K V FW + L+ Sbjct: 6347 ENVKSAANLIVEEEDLRIVE-----------PLKD---IETMEKKSVTFWCKVNRLN--V 6390 Query: 1046 SYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVL 1105 + ++ N EV + DK ++ + F +EG Y V G+ KS + L++ Sbjct: 6391 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFP--DEGEYIVTA--GQDKSVAELLI 6446 Query: 1106 IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW-- 1163 I EA + E L Q VTE + C+++ K KW Sbjct: 6447 I---------EAPTEFVEHLEDQ----------TVTEFDDAVFSCQLSREKANV--KWYR 6485 Query: 1164 ----LKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219 +K+ Y+ E ++ R L+I D EY ++D + + A Sbjct: 6486 NGREIKEGKKYKFEKDGSIHR----LIIKDCRLDDECEYACGVEDRKSR-------ARLF 6534 Query: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279 +++ + + R P +L P G + + D+++V W + + + ++ Sbjct: 6535 VEEIPVEIIR------PPQDILEAP-GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQM 6587 Query: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 ++ LQIC+ +D+G+Y F D EA A+ + A Sbjct: 6588 MSEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIK 6631 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 ++ ++ DV GK L + P E WFK ++ + ++ EQ Sbjct: 6632 TADQDLVV----DV-----GKPLTMVVPYDAYPKAEAEWFKENEPLS-TKTIDTTAEQTS 6681 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + K D G+Y I ++NK+G Sbjct: 6682 FRILEAK---KGDKGRYKIVLQNKHG 6704 Score = 58.5 bits (140), Expect = 4e-08 Identities = 36/101 (35%), Positives = 61/101 (60%), Gaps = 6/101 (5%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + RL+S TV + V+L V G PTPVV++Y+DG+ I + + ++I +++ Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEE 254 L I A +D+ TYS ATN+ G+ ++ A ++V +G+EE Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV---QGEEE 198 Score = 58.2 bits (139), Expect = 6e-08 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207 E IS P I+ L+ TV K G P P W KDG I Q GKY++ Sbjct: 26474 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG---GKYKLSE 26530 Query: 208 NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253 + G LEI++ D D+ Y+ N+ G VS++ + ++ + E Sbjct: 26531 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTE 26576 Score = 57.0 bits (136), Expect = 1e-07 Identities = 109/586 (18%), Positives = 215/586 (36%), Gaps = 97/586 (16%) Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--------PGTKEISAGVDEQG 924 KV +GK + +R V G+ T++ A TK + E+G Sbjct: 5868 KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 5927 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 + +C+ + ++ W K+ EI ++++I G KL + + ED+ TY+ Sbjct: 5928 ATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5986 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPD 1044 D S + + P +E L L++ ++ +K RF + E + Sbjct: 5987 KDFK-TSCNLNVVPPHVEFLRPLTD--------------LQVREKEMARF--ECELSREN 6029 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 A ++ + E+ + + I A I +V+++ +++E Y+ ++ + Sbjct: 6030 AKVKWFKDGAEIKKGKKYDIISKGAVRI--LVINKCLLDDEAEYSCEVRTART------- 6080 Query: 1105 LIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL 1164 TVLEE K + +V+E ++LVC+V+ E + W Sbjct: 6081 ---SGMLTVLEEEAVFTKNL-----------ANIEVSETDTIKLVCEVSKPGAEVI--WY 6124 Query: 1165 K-DDVLYETETLPNLERGICELL-IPKLSKKDHGEYKATLKDDRGQ-DVSILEIAGKVYD 1221 K D+ + ET L G +L I +D G Y L R V + E+A + Sbjct: 6125 KGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFI- 6183 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGG 1281 L++L EG + + + V W D + S + + Sbjct: 6184 -----------SKPQNLEIL---EGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIA 6229 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + L + + T +D G Y + + AA Sbjct: 6230 DGKKRVLVVKDATLQDMGTYVVMVGAAR------------------------AAAHLTVI 6265 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV 1401 + R++ L D + E + + C V + WF+N++ I S + + + Y Sbjct: 6266 EKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY- 6322 Query: 1402 SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 ++ I+ +D Y++++ N + GE + ++ E + + P Sbjct: 6323 TLRIRDAHLDDQANYNVSLTN-HRGENVKSAANLIVEEEDLRIVEP 6367 Score = 56.2 bits (134), Expect = 2e-07 Identities = 98/501 (19%), Positives = 188/501 (37%), Gaps = 63/501 (12%) Query: 948 EEISD----DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EEIS E K+ KL LK + L + V S + S V EE+ + Sbjct: 26598 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIV--HEEITK 26655 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 S E++ +K+ ++G+ R L+A +++ ++++N E+++SE +R Sbjct: 26656 TSQASEEVRTHA-EIKAFSTQMSINEGQ-RLVLKA-NIAGATDVKWVLNGVELTNSEEYR 26712 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 + + + E T + +G K Q L L KE Sbjct: 26713 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL---------------SKE 26757 Query: 1124 FLRKQGPHF-AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERG- 1181 P F ++ ++ E V C+++ + +W K+++ + ++ R Sbjct: 26758 L--SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEI-EWFKNNLPISISSNVSISRSR 26814 Query: 1182 -ICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKV 1240 + L I S D G+Y K+ RGQ + + M+L + + V Sbjct: 26815 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL-------MVLPLVEEPSREV----V 26863 Query: 1241 LCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGK 1300 L T LQ + + ++++ ++A SS EM + + + Sbjct: 26864 LRTSGDTSLQG--SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM-- 26919 Query: 1301 YTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG-----RLIGGLPDVVT 1355 + +++S +F + Q +++ G I LP ++ Sbjct: 26920 -----------QESFVEMSSSSF-MGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDIS 26967 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVTSEDSG 1414 I EGK L + C G P PEV W + I E +E ++ I V +D G Sbjct: 26968 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGG 27027 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 Y++++ N++G + V + + Sbjct: 27028 LYTLSLGNEFGSDSATVNIHI 27048 Score = 55.5 bits (132), Expect = 4e-07 Identities = 40/202 (19%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Query: 1247 IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIF 1306 ++ C ++ + +V W ++ +SE I + +A L + + T+ D G Y ++ Sbjct: 25213 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25272 Query: 1307 DGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK-NRGRLIGGLPDVV------TIMEG 1359 + +L + E + + + + + RL+ P+ T G Sbjct: 25273 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25332 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH---FSVKVEQAKYVSMTIKGVTSEDSGKY 1416 + + T+ +P+P V W+K+ Q I+ ++ ++ + ++ Y +TI VT++D +Y Sbjct: 25333 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEY 25391 Query: 1417 SINIKNKYGGEKIDVTVSVYKH 1438 ++ +NKYG + ++V H Sbjct: 25392 TVVARNKYGEDSCKAKLTVTLH 25413 Score = 55.5 bits (132), Expect = 4e-07 Identities = 69/264 (26%), Positives = 108/264 (40%), Gaps = 19/264 (7%) Query: 12 RHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLS-QRSSSQRASSQTSLGGTICRV 70 R S Q + L E ASK S + + S ++S ++TS R Sbjct: 26606 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRT 26665 Query: 71 CA--KRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEE--------DVHLARS 120 A K STQ + R ++ +A + K EL + EE D L Sbjct: 26666 HAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK 26725 Query: 121 QA--RDKLDKYAIQQMMEDKLAWERH-TFEERISRAPEILVRLRSHTVWERMSVKLCFTV 177 QA RD+ I + E + + T + +S AP + + RS + E +V + Sbjct: 26726 QASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI 26785 Query: 178 QGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQ 237 G P+P ++W+K+ I ++ I + V++LEI A D+ Y+ A N GQ Sbjct: 26786 SGEPSPEIEWFKNNLPISISS---NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ 26842 Query: 238 VSTNAAVVVRRFRGDEEPFRSVGL 261 S A+++V EEP R V L Sbjct: 26843 CSATASLMVLPL--VEEPSREVVL 26864 Score = 55.1 bits (131), Expect = 5e-07 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 +P+ +TI GK L + V+G P P W K + ++ S H +V + + + IK VT Sbjct: 12532 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVT 12590 Query: 1410 SEDSGKYSINIKNKYG--GEKIDVTV 1433 +DSG YS+ +N G +KI V V Sbjct: 12591 RKDSGYYSLTAENSSGTDTQKIKVVV 12616 Score = 54.7 bits (130), Expect = 6e-07 Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 29/243 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P ++ L++ TV E SV L + G+P+P V WY++ I + + ++I G+ Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIAR 953 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVR--------------RFRGDEEPFRS- 258 L I A +D+ ++ A N G VST+ + V+ +F +E+ F Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013 Query: 259 ---VGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAE 315 V L P F+ K V EG +V C + P +P Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVY 1068 Query: 316 WYRDDVLLKESKWTKMFFGE--GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W + V L K+ + + G+ L S DD G YT+ + ++ G + SA L + Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LE 1127 Query: 374 DAD 376 +AD Sbjct: 1128 EAD 1130 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L+ GL +V T++EG+++ L C + G P P V W++ D I+ S F + Q+ + I Sbjct: 899 LVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMI 956 Query: 1406 KGVTSEDSGKYSINIKNKYG 1425 + +EDSG+++ + N+ G Sbjct: 957 REAFAEDSGRFTCSAVNEAG 976 Score = 52.0 bits (123), Expect = 4e-06 Identities = 51/223 (22%), Positives = 91/223 (40%), Gaps = 31/223 (13%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 ++AP L+S V E + + GFP P V W++DG +I + PG +I + G Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPG-VQISFSDG 61 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 L I ++ YS ATN GQ ++ A ++V + + P Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV---KAETAP--------------- 103 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 F+++ R+G V L+ + P P ++YRD ++ S + Sbjct: 104 -------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLDFQ 151 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 + SL + + +D G Y++ + G + +A L V+ Sbjct: 152 ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 52.0 bits (123), Expect = 4e-06 Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 27/207 (13%) Query: 1245 EGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFE 1304 E + L+C + + V W +D +I SS +I +A L I E +D G++T Sbjct: 912 ESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 970 Query: 1305 IFDGKDNHQRSLDLSGQAFDE-----------------AFAEFQQ--FKAAAFAEKNRGR 1345 + S L+ Q +E F E + + E+ G Sbjct: 971 AVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGP 1030 Query: 1346 LIGGLPDVVT------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKV-EQA 1398 P +T ++EG ++ C V GNP P V W K+ + + V +Q Sbjct: 1031 GEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + I ++D+G+Y+I ++NK+G Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHG 1117 Score = 50.8 bits (120), Expect = 9e-06 Identities = 113/619 (18%), Positives = 230/619 (37%), Gaps = 109/619 (17%) Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---GTKEISAGVDEQGNIYL 928 L + D+ + V+A+N G + + +LV+A+ T+E+ V ++ + Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAG---ETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146 Query: 929 GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 F+C+ + W K E+ + +++++ + L + D D YS + + + Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE 2206 Query: 989 GVSSS-----------FVLDPEELERLMALSNEIK-------------NPTIPLKSELAY 1024 V ++ FV + +++E + S E++ + + LKS Y Sbjct: 2207 NVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKY 2266 Query: 1025 EIFDK-GRVRFWLQAEHLSPDASYRFIIN----------------------DREVSDSEI 1061 I + GR ++ Y F+I+ D++V + +I Sbjct: 2267 TITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDI 2326 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +++ + +E V + E + + V I K QS ++LI D K F Sbjct: 2327 VQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK---QSHMLLIEDMTKEDAGNYSFTI 2383 Query: 1122 KEFLRKQGPHFAEYL--------HWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE 1173 + Y +V E + L CKV+ +V +L D+ + + Sbjct: 2384 PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDD 2443 Query: 1174 TLPNLERGICE-LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCG 1232 + + +G + L+I + D G YK I G+V + L++ ++ Sbjct: 2444 RVQAIVKGTKQRLVINRTHASDEGPYKL--------------IVGRVETNCNLSVEKI-- 2487 Query: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 K L+ L E + ++ + V W KD +I S +I ++ L + Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLN 2547 Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352 + D+GKYTF + G++ L ++G A + + Sbjct: 2548 MMKDDEGKYTF--YAGENMTSGKLTVAGGAISKPLTD----------------------- 2582 Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 T+ E + C V NPD + W ++ + + L+ + + + K + I +D Sbjct: 2583 -QTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKR-RLIIAATKLDD 2639 Query: 1413 SGKYSINIKNKYGGEKIDV 1431 G+Y+ + K+ V Sbjct: 2640 IGEYTYKVATSKTSAKLKV 2658 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 6/107 (5%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P +T+ EG++ +C G P P V W + Q + S V + K + I V + Sbjct: 26195 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQA 26253 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA---PPQQAKPK 1454 D G YS+ ++N G ++ + T+++ K ++ + A PP+ P+ Sbjct: 26254 SDEGNYSVVVENSEGKQEAEFTLTIQK--ARVTEKAVTSPPRVKSPE 26298 Score = 49.7 bits (117), Expect = 2e-05 Identities = 64/265 (24%), Positives = 99/265 (37%), Gaps = 48/265 (18%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 +E + + P + L S V +V+ V G P P +QW+ + LI + + E Sbjct: 3412 KEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDV-VFHFE 3470 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRR------------------ 248 + G+ + I A + YS A N+ G+ + A + V Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEME 3530 Query: 249 --------FRGDEEPFRSVGLPIG-----LPLSSMIPY--THFDVQFLEKFGVTFRRE-- 291 +EE S L + L L S P T FD + E G F +E Sbjct: 3531 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSE-KEGTGPIFIKEVS 3589 Query: 292 ------GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHL 345 G+ TL T++ P +P+ +W+ + VLL S K F SL Sbjct: 3590 NADISMGDVATLSVTVIGIP-----KPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3644 Query: 346 HKDDEGLYTLRIVSRGGVSDHSAFL 370 +DEG YT + G + SA+L Sbjct: 3645 KLEDEGEYTCMASNDYGKTICSAYL 3669 Score = 48.9 bits (115), Expect = 4e-05 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P+ V ++EG+T C V G P P+V W+ N Q I+ S+ F V+ + Y + I S Sbjct: 1801 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY--LDIVDCKS 1858 Query: 1411 EDSGKYSINIKNKYG 1425 D+G+ + +N G Sbjct: 1859 YDTGEVKVTAENPEG 1873 Score = 48.5 bits (114), Expect = 5e-05 Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 26/207 (12%) Query: 1261 KVNWCHKDAKISSSE--HMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDL 1318 +V+W IS+S ++I S+ A L I T+ + G+Y+ + +G Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNG---------- 85 Query: 1319 SGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIW 1378 SGQA A + AE + L + T+ +G + L V G P P V + Sbjct: 86 SGQATSTA-------ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKF 137 Query: 1379 FKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKH 1438 +++ +IQ S F + E Y S+ I EDSG YS+N N G + T + Sbjct: 138 YRDGAEIQSSLDFQISQEGDLY-SLLIAEAYPEDSGTYSVNATNSVG--RATSTAELLVQ 194 Query: 1439 GEKIPDMAPPQQAKPKLIPASASAAGQ 1465 GE + P ++ K + A S + Q Sbjct: 195 GE---EEVPAKKTKTIVSTAQISESRQ 218 Score = 48.5 bits (114), Expect = 5e-05 Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 13/227 (5%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKY-RIESNYGVH 212 P I+ L+ E + V G V + KD + +P ++ R+ + Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI-----KPSRFFRMTQFEDTY 3353 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 LEI A +D TY+ VA+NA GQVS+ A + + F EE + + L +S Sbjct: 3354 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKE 3413 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 F++ GETV + P +P +W+ + L+ +K Sbjct: 3414 PLGQKPSFIQPLSSLRVHNGETVRFHARVSGIP-----KPEIQWFHNQQLILPTKDVVFH 3468 Query: 333 FGE--GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADP 377 F E G A + + + G Y+ + + G + +A L V P Sbjct: 3469 FEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAP 3515 Score = 48.5 bits (114), Expect = 5e-05 Identities = 124/606 (20%), Positives = 230/606 (37%), Gaps = 106/606 (17%) Query: 832 LWKAPVYSGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 L+ V+ G + + + ++ E D G+W Q TA+ ++ ++ GK ++ + Sbjct: 5385 LYGVEVFVGET--AHFEIELSEPDVHGQWKLKGQPLTASPDCEI--IEDGKKHILILHNC 5440 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEIS-------AGVDEQGNIYLGFDCQEMTDASQFTW 943 G+ S + A KE+ + V F+C+ + F W Sbjct: 5441 QLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRW 5500 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 K +EI+ D+RF++ G + +K+ ED Y D S +++ L+ Sbjct: 5501 LKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH-TSGKLIIEGIRLKF 5559 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 L PLK A E K F ++ H + ++ ND+ + + Sbjct: 5560 L-----------TPLKDVTAKE---KESAVFTVELSH--DNIRVKWFKNDQRLHTTRSVS 5603 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 ++ + T I SI++ V+ ++ + +A TVLE Sbjct: 5604 MQDEGKTHSI--TFKDLSIDDTSQIRVE----------AMGMSSEAKLTVLE-------- 5643 Query: 1124 FLRKQGPHFAEYLH-WDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETETLPNLER 1180 P+F L + E+ EV L C++ +K + KW KD ++ + + Sbjct: 5644 ----GDPYFTGKLQDYTGVEKDEVILQCEI--SKADAPVKWFKDGKEIKPSKNAVIKADG 5697 Query: 1181 GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV-YDDMILAMSRVCGKSASPLK 1239 L++ K K D G+Y D G D + +GK+ +D + + R PL Sbjct: 5698 KKRMLILKKALKSDIGQYTC----DCGTD----KTSGKLDIEDREIKLVR-------PLH 5742 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 + E + + D++ NW K A LQ + K++G Sbjct: 5743 SVEVMETETARFETEISEDDIHANWKLKGE----------------ALLQTPDCEIKEEG 5786 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE-KNRGRLIGGLPDV--VTI 1356 K + H LD +G +FQ + A + + R+IG L + VT+ Sbjct: 5787 KIHSLVL-----HNCRLDQTGG------VDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5835 Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 G+T C + D V W+ + ++ S+ V + K ++T++ V ED+G+ Sbjct: 5836 TAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKV-VPRSEGKVHTLTLRDVKLEDAGEV 5893 Query: 1417 SINIKN 1422 + K+ Sbjct: 5894 QLTAKD 5899 Score = 48.5 bits (114), Expect = 5e-05 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D +TI G+ LT G P P+V WFK++ D+ + +K A IK S Sbjct: 10454 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRS- 10512 Query: 1412 DSGKYSINIKNKYGGEK 1428 DSGKY + ++N G K Sbjct: 10513 DSGKYCVVVENSTGSRK 10529 Score = 48.5 bits (114), Expect = 5e-05 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G++ + ++G P P + W K DQ++ + +K S+++K Sbjct: 16179 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFA-TSLSVKDAVRV 16237 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y + KN G + V V V Sbjct: 16238 DSGNYILKAKNVAGERSVTVNVKV 16261 Score = 48.5 bits (114), Expect = 5e-05 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 15/145 (10%) Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQA-FDEAFAEFQQFKAAAFAEKNRGRLIGGLP 1351 P K KY+F + ++++ G + + E+ AE + + + L L Sbjct: 23033 PDLKMGQKYSFRV--------AAVNVKGMSEYSESIAEIEPVERIEIPDLE---LADDLK 23081 Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 VTI G +L L +V G P P + W K Q I L+ + ++ Y + + V Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTES-YSLLIVDKVNRY 23138 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSVY 1436 D+GKY+I +N+ G + V V VY Sbjct: 23139 DAGKYTIEAENQSGKKSATVLVKVY 23163 Score = 48.1 bits (113), Expect = 6e-05 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V I EG L + GNP+P+++W KN I ++ +++E K ++ I S+D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIP 1457 S Y+ NK G + V+V + A P+ + +IP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVE------VEFAEPEPERKLIIP 1617 Score = 48.1 bits (113), Expect = 6e-05 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L ++ I G +L L + G P PEV W K D +I+ + V + + S+ + V Sbjct: 16576 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT---SSFTSLVLDNVN 16632 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ ++N G + VTV V Sbjct: 16633 RYDSGKYTLTLENSSGTKSAFVTVRV 16658 Score = 47.4 bits (111), Expect = 1e-04 Identities = 91/436 (20%), Positives = 177/436 (40%), Gaps = 67/436 (15%) Query: 999 EELERLMALSNEIKNPTI-PLKSEL-----AYEIFDKGRVRFWLQAEHLSPDASYRFIIN 1052 EE ++ +A +I PT P K EL A +IF+ R Q DA +R + Sbjct: 2001 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFE----RIQSQTVGQGSDAHFRVRVV 2056 Query: 1053 DREVSDSEIHR--IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAF 1110 + + E ++ +K +++ I + + + I D A+ +S+++ Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIY------WYWPEDNVCELVIRDVTAEDSASIMV----- 2105 Query: 1111 KTVLEEAEFQRKEFLRKQGPH---FAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDD 1167 K + E FL Q F + L V +E + + ++ KW KD Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Query: 1168 V-LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRG-QDVSILEIAGKVYDDMI 1224 + ++E + + +R + L I + D +Y L +D + + L + G V + + Sbjct: 2166 MEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV- 2224 Query: 1225 LAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEE 1284 K ++V + G L+C + + ++ W H D ++ S+ I Sbjct: 2225 --------KELQDIEVPESYSG-ELECIVS--PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1285 MAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG 1344 L + + T++D+G+Y+F + DGK + + K A Sbjct: 2274 RQNLTVKDVTKEDQGEYSF-VIDGKKTTCK----------------LKMKPRPIA----- 2311 Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 ++ GL D + EG + L V E +W K+ Q++Q S+ + +++ ++ + Sbjct: 2312 -ILQGLSD-QKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHM-LL 2367 Query: 1405 IKGVTSEDSGKYSINI 1420 I+ +T ED+G YS I Sbjct: 2368 IEDMTKEDAGNYSFTI 2383 Score = 47.0 bits (110), Expect = 1e-04 Identities = 116/553 (20%), Positives = 198/553 (35%), Gaps = 103/553 (18%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS--VSVSDT 987 F+C + TW K I + + + G KL++ + D G Y+ + + + Sbjct: 4766 FECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4825 Query: 988 DGVSSSFVLDPEELERLMALSNE----IKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 + S++ ++ E R + E +K + L EL +K R W + + Sbjct: 4826 EKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL-----NKERDVVWRKDGKIVV 4880 Query: 1044 DASYRFI-----------INDREVSDS--------EIHRIKCDKATGIIEMVMDRFSIEN 1084 + R + IND + +D+ + ++C ++E++ D Sbjct: 4881 EKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL---- 4936 Query: 1085 EGTYTVQIHDGKAKSQSSLVLIGDAFKTVLE----------EAEFQRKEFLRKQGPHF-- 1132 I D K + + + D K AE K + + G H Sbjct: 4937 ----VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYL 4992 Query: 1133 --AEYLHWDVTE---ECE-VRLVCKVANTKKET-VFKWLKDDVLYETET----------- 1174 + D+ E E E R K+ ++E + K ++D +YE E+ Sbjct: 4993 KIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD 5052 Query: 1175 LPNLERGICELLIPKLS---KKDHGEYKATL-KDDRGQDVSILEIAGKVYDDMILAMSRV 1230 +P + ELL P + K + G+ TL K Q +L A IL + + Sbjct: 5053 IPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEI 5112 Query: 1231 CGKSASPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL 1288 A PLK + PE R +C + T E V W I SS+ I + L Sbjct: 5113 ELDFAVPLKDVTVPERRQARFECVL---TREANVIWSKGPDIIKSSDKFDIIADGKKHIL 5169 Query: 1289 QICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIG 1348 I + D+G YT E+ E ++ A F R + + Sbjct: 5170 VINDSQFDDEGVYTAEV-----------------------EGKKTSARLFVTGIRLKFMS 5206 Query: 1349 GLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 L D T+ EG+T C + + V+WFKND + S + E K + +K V Sbjct: 5207 PLEDQ-TVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSE-GKTHKLEMKEV 5263 Query: 1409 TSEDSGKYSINIK 1421 T +D + +K Sbjct: 5264 TLDDISQIKAQVK 5276 Score = 47.0 bits (110), Expect = 1e-04 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+T+ G+T+ + V G P+P++ W K + + + + ++ V + IK Sbjct: 11544 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRA 11602 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY I+ KN G + V+V Sbjct: 11603 DHGKYIISAKNSSGHAQGSAIVNV 11626 Score = 47.0 bits (110), Expect = 1e-04 Identities = 48/209 (22%), Positives = 81/209 (38%), Gaps = 22/209 (10%) Query: 1238 LKVLCTPEGIRLQCFMKYFTDEMK-VNWCHKDAKISSSEHMRIGGSEEMAW-LQICEPTE 1295 LK + E +L C ++ K V W K+ + H + S + + L+I TE Sbjct: 26352 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26411 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAF----------DEAFAEFQQFKAAAFAEKNRGR 1345 D+G+Y EI + +L GQAF E Q+ + K + Sbjct: 26412 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26471 Query: 1346 L---IGGLPDVVTIMEGKTLN------LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE 1396 I P +VT ++ T++ G P P IW K+ + I + + + Sbjct: 26472 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSED 26531 Query: 1397 QAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + + I + DSG Y+ +KN G Sbjct: 26532 KGGFF-LEIHKTDTSDSGLYTCTVKNSAG 26559 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 +LI GL + G T+ + G P P W + +I+ EH++V+ + V +T Sbjct: 11143 KLIEGL----VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LT 11197 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 IK D+G+Y I + N G + + V ++V Sbjct: 11198 IKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228 Score = 45.8 bits (107), Expect = 3e-04 Identities = 24/79 (30%), Positives = 39/79 (49%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 +EG+T V G P PE WF + Q I V +++ S+ I T DSG++ Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482 Query: 1417 SINIKNKYGGEKIDVTVSV 1435 ++ +N+ G I V ++V Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501 Score = 45.8 bits (107), Expect = 3e-04 Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 37/177 (20%) Query: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 P V+WYKDG + E KYR+ S+ VH L I D D YS V V T Sbjct: 2155 PFVKVKWYKDGM---EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKT 2210 Query: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 A ++V +++ + V+ L+ V GE L+C Sbjct: 2211 TAKLIVE--------------------GAVVEF----VKELQDIEVPESYSGE---LEC- 2242 Query: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRI 357 +V+P+ +WY +DV LK + + G+ +L+ + K+D+G Y+ I Sbjct: 2243 -IVSPE----NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI 2294 Score = 45.8 bits (107), Expect = 3e-04 Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 25/202 (12%) Query: 1257 TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEP-TEKDKGKYTFEIFDGKDNHQRS 1315 T+ +VNW ++ + S E + + L I + TE +G+Y E + Sbjct: 4392 TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCE----------A 4441 Query: 1316 LDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375 L+ SG+ A + K AA K + + + + G TC + P+ Sbjct: 4442 LNDSGKTATSA--KLTVVKRAAPVIKRK-------IEPLEVALGHLAKFTCEIQSAPNVR 4492 Query: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 WFK ++I S+ S++ +KY+ S+ I D G+Y+ N+YG T++ Sbjct: 4493 FQWFKAGREIYESDKCSIR--SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 4550 Query: 1435 VYKHG--EKIPDMAPPQQAKPK 1454 V G +K+ + P ++ +PK Sbjct: 4551 VTVPGGEKKVRKLLPERKPEPK 4572 Score = 45.8 bits (107), Expect = 3e-04 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VV + TL L T+ G P+PEV W K + L++ ++V + + + I VT Sbjct: 18741 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEG--ILTDRAQIEV-TSSFTMLVIDNVT 18797 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSG+Y++ ++N G + V V V Sbjct: 18798 RFDSGRYNLTLENNSGSKTAFVNVRV 18823 Score = 45.4 bits (106), Expect = 4e-04 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 I G TL L+ + G P P+V W K D+D V +K + I+ ED G Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10914 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 YS+ ++N G + + V V V Sbjct: 10915 YSLTVENPAGSKTVSVKVLV 10934 Score = 45.1 bits (105), Expect = 5e-04 Identities = 91/479 (18%), Positives = 176/479 (36%), Gaps = 75/479 (15%) Query: 943 WCKSYEEISDDERFKIETVGDH-SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEEL 1001 W K+ +I +R D+ +L +++ ED + V + G +SS + Sbjct: 2065 WYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Query: 1002 ERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEI 1061 ++L+ + E+++ K +A + E P ++ + EV + + Sbjct: 2125 KQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGMEVHEGDK 2173 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +R+ D+ + ++ S + E V + D K+ + L++ G + V E + + Sbjct: 2174 YRMHSDRKVHFLSILTIDTS-DAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIE- 2231 Query: 1122 KEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--E 1179 V E L C V+ E KW +DV ++ + Sbjct: 2232 ------------------VPESYSGELECIVSPENIEG--KWYHNDVELKSNGKYTITSR 2271 Query: 1180 RGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLK 1239 RG L + ++K+D GEY + D + + + L+ +VC Sbjct: 2272 RGRQNLTVKDVTKEDQGEYSFVI-DGKKTTCKLKMKPRPIAILQGLSDQKVC-------- 2322 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 EG +Q +K + ++ W ++ S+ + I ++ L I + T++D G Sbjct: 2323 -----EGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAG 2377 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEG 1359 Y+F I +L LS ++ +I L D V ++EG Sbjct: 2378 NYSFTI--------PALGLSTSGRVSVYSV---------------DVITPLKD-VNVIEG 2413 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 L C V V W+ ND+ I+ + V+ K + I + D G Y + Sbjct: 2414 TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ-RLVINRTHASDEGPYKL 2471 Score = 45.1 bits (105), Expect = 5e-04 Identities = 21/84 (25%), Positives = 42/84 (50%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+T L + G P P+V+W K+ ++++ + + ++ +K Sbjct: 18343 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18402 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + + N G + I +TV V Sbjct: 18403 DGGQYILKLSNVGGTKSIPITVKV 18426 Score = 44.7 bits (104), Expect = 7e-04 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V ++EG T + G P PEV WF++ Q I S V++ + +TI VT + Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74 Query: 1413 SGKYSINIKNKYG 1425 SG+YS+ N G Sbjct: 75 SGRYSLKATNGSG 87 Score = 44.7 bits (104), Expect = 7e-04 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + I G++L + V G P P V WFK+ +I+ + + + S+ ++ T + Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRD 21652 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 G Y++ KN G K ++ V V Sbjct: 21653 HRGVYTVEAKNASGSAKAEIKVKV 21676 Score = 44.3 bits (103), Expect = 9e-04 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G+T L V G P P + W + D++I+ S +K K + + +K Sbjct: 17261 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL-LIVKDAIRI 17319 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + N G + V V V Sbjct: 17320 DGGQYILRASNVAGSKSFPVNVKV 17343 Score = 43.9 bits (102), Expect = 0.001 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E SV V G P P ++W KDG + + P I + L I +DT Sbjct: 25436 EGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25493 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRS 258 Y ATN G S A + V R R ++ F+S Sbjct: 25494 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKS 25525 Score = 43.5 bits (101), Expect = 0.001 Identities = 60/266 (22%), Positives = 105/266 (39%), Gaps = 54/266 (20%) Query: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238 G PT VV+W DG + A + R+ + +G +L+ A D+ + ATN +G Sbjct: 1684 GDPTMVVEWLHDGKPLEAA---NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTD 1740 Query: 239 STNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF----------GVTF 288 T+A ++V+ DE+ L S +P +Q +E+ GVT Sbjct: 1741 HTSATLIVK----DEK---------SLVEESQLPEGRKGLQRIEELERMAHEGALTGVTT 1787 Query: 289 RR------------------EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 + EGET +C + P QP+ WY + L+++SK + Sbjct: 1788 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFR 1842 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR---DADPLVTGAPGAPM 387 + + +G L D G + + GV +H L ++ D ++ AP Sbjct: 1843 VRY-DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1901 Query: 388 DLQCHDANR-DYVIVTWKPPNTTTES 412 + H+ + + + P TTE+ Sbjct: 1902 EFHVHEPGKLQFEVQKVDRPVDTTET 1927 Score = 43.5 bits (101), Expect = 0.001 Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 8/141 (5%) Query: 107 ELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVW 166 EL H +++ +A + K I DK+ AP+I R++S TV Sbjct: 1991 ELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSM------EAPKIFERIQSQTVG 2044 Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 + V G P P +WYK+G I ++ Y E N V L I +D+A+ Sbjct: 2045 QGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN--VCELVIRDVTAEDSAS 2102 Query: 227 YSAVATNAHGQVSTNAAVVVR 247 A N G+ S++A ++V+ Sbjct: 2103 IMVKAINIAGETSSHAFLLVQ 2123 Score = 43.5 bits (101), Expect = 0.001 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G + +T G P P V+W K D D++ + + S+TI+ DSGK Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRT---SLTIENANRNDSGK 19882 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ I+N + + V V Sbjct: 19883 YTLTIQNVLSAASLTLVVKV 19902 Score = 43.1 bits (100), Expect = 0.002 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM-FFGEGQASLSFSHLHKDD 349 EG VT C M P P+ WY+D +K + +M F +G+ASL + +D Sbjct: 1258 EGMGVTFHCKMSGYP-----LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAP 383 EG+YT + G + S L+V A PL GAP Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYVEPAAPL--GAP 1344 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%) Query: 145 TFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR 204 T +++ + P+I++ V E + + V G+P P V WY +G LI ++ ++R Sbjct: 1786 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK---RFR 1842 Query: 205 IESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSV 259 + + G+H L+I DT A N G + + +++ E FRSV Sbjct: 1843 VRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ----REDFRSV 1892 Score = 43.1 bits (100), Expect = 0.002 Identities = 80/376 (21%), Positives = 138/376 (36%), Gaps = 82/376 (21%) Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 VL E TK + A ++ + C+ ++ W K EEI + R++I T G Sbjct: 6086 VLEEEAVFTKNL-ANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6144 Query: 965 SKLYLKNPDKEDLGTYSVSV--SDTDG------VSSSFVLDPEELERLMALSNE----IK 1012 L ++N ED G Y+ + S TDG +++ F+ P+ LE L E I Sbjct: 6145 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 6204 Query: 1013 NPTIP---------LKSELAYEIFDKGRVRFWL--------------------QAEHLSP 1043 + P L+S Y++ G+ R + A HL+ Sbjct: 6205 KESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV 6264 Query: 1044 DASYRFII--NDREVSDSEIHRIKCDKATGII--------EMVMDR---FSIENEGTYTV 1090 R ++ D V + + C+ T E + D ++ + YT+ Sbjct: 6265 IEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTL 6324 Query: 1091 QIHDGKAKSQSSLVL---------IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVT 1141 +I D Q++ + + A ++EE + + E L+ + Sbjct: 6325 RIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLK----------DIETM 6374 Query: 1142 EECEVRLVCKVANTKKETVFKWLK--DDVLYETETLPNLERGICELLIPKLSKKDHGEYK 1199 E+ V CKV + KW K ++V ++ +++ L I D GEY Sbjct: 6375 EKKSVTFWCKV--NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI 6432 Query: 1200 ATLKDDRGQDVSILEI 1215 T GQD S+ E+ Sbjct: 6433 VT----AGQDKSVAEL 6444 Score = 43.1 bits (100), Expect = 0.002 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G ++ L G P P +W K D ++ L + ++T++ D+GK Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 22053 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ ++N G + I TV V Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE-QAKYVSMTIKGV 1408 L V+T+ G T+ L V G P PEV W K+ L+ VK++ +A ++ Sbjct: 11835 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11894 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY + N G TV+V Sbjct: 11895 KRSDGGKYVVTATNTAGSFVAYATVNV 11921 Score = 42.7 bits (99), Expect = 0.003 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + ++T+ G + L TVFG P P V W K+ ++ +E + + Q ++ + V Sbjct: 12929 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVN 12987 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 +DSG Y+I +N G + + + V Sbjct: 12988 RKDSGDYTITAENSSGSKSATIKLKV 13013 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 V + G+ +++ G PDP + W K I + H+ V V ++ + GV +D+ Sbjct: 24665 VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDA 24724 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 G Y + KN++G ++ V + V +PD PP+ K Sbjct: 24725 GFYVVCAKNRFGIDQKTVELDV----ADVPD--PPRGVK 24757 Score = 42.4 bits (98), Expect = 0.003 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+ L + + G P P + W K+ +I+ + + + +T+K Sbjct: 19425 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRR 19483 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D+G+Y + +KN G + V V Sbjct: 19484 DTGQYVLTLKNVAGTRSVAVNCKV 19507 Score = 42.0 bits (97), Expect = 0.004 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKN----DQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + IM GKTL + V G P P +W K D+D + ++ K E + IK Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8795 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 +D G+Y I N G + V V+ + D+ P Sbjct: 8796 RKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKP 8833 Score = 42.0 bits (97), Expect = 0.004 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 1350 LPDVVTIMEGKTLNLTC-TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 + D +TI G T+ L ++ G P P+ W K +DI+ S+ + + +TIK Sbjct: 14012 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYA 14070 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 T +D+G+Y+I N +G + V V+V Sbjct: 14071 TRKDAGEYTITATNPFGTKVEHVKVTV 14097 Score = 42.0 bits (97), Expect = 0.004 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G+ + L + G P P WF ++ SE +V+ K +TI+ T D+ Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH-TKVAKLTIRETTIRDT 23434 Query: 1414 GKYSINIKNKYG 1425 G+Y++ +KN G Sbjct: 23435 GEYTLELKNVTG 23446 Score = 41.6 bits (96), Expect = 0.006 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Query: 1349 GLPDVVTIM-EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 GLPD+ + E L + G P P V W K + + SV+ A ++ + Sbjct: 13614 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYD 13672 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+GKY+I +KN G ++ +++ V Sbjct: 13673 CQKSDAGKYTITLKNVAGTKEGTISIKV 13700 Score = 41.6 bits (96), Expect = 0.006 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VVTI TL L + G P PEV W ++ + + S++ + Y + + V Sbjct: 15494 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHG--ESLDKASIE-STSSYTLLIVGNVN 15550 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 DSGKY + ++N G + V V V + PPQ K K Sbjct: 15551 RFDSGKYILTVENSSGSKSAFVNVRV------LDTPGPPQDLKVK 15589 Score = 41.6 bits (96), Expect = 0.006 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 +VV G ++ L + G P P + W+K+D+++Q + V+ S+ IK Sbjct: 20508 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20566 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 +SG Y + ++N G + V + Sbjct: 20567 NSGCYELKLRNAMGSASATIRVQI 20590 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L G ++T G + + G P P+V W + ++ ++ S+ + + ++T+ Sbjct: 22277 LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDR-TTLTV 22335 Query: 1406 KGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 K DSG+Y + ++N G + VTV V Sbjct: 22336 KDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365 Score = 40.8 bits (94), Expect = 0.010 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%) Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 W+ EP + K + T + +GK R L+ Q + ++ +A E L Sbjct: 7262 WVACGEPVAETKMEVT-GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7320 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIK 1406 L +T+ G + L TV G P+P++ W K D ++ + +++ K ++TI Sbjct: 7321 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIV 7379 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+G Y I N G V V+V Sbjct: 7380 DSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408 Score = 40.4 bits (93), Expect = 0.013 Identities = 68/297 (22%), Positives = 116/297 (39%), Gaps = 49/297 (16%) Query: 1150 CKVANTKKETVFKWLKDDVL----YETETLPNLERGICELLIPKLSKKDHGEYKATLKDD 1205 C+V K V+ W K V Y + N + G C+L+I D GEY +++ Sbjct: 1057 CQVGGNPKPHVY-WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNK 1115 Query: 1206 RGQ---DVSILEIAG-----KVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFT 1257 G+ S+LE A K +M L ++V P KV T G + K + Sbjct: 1116 HGETSASASLLEEADYELLMKSQQEM-LYQTQVTAFVQEP-KVGETAPGFVYSEYEKEYE 1173 Query: 1258 DEMKV--NWCHKDAKISSS----EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDN 1311 E + KD + + + I EE ++ + E K T E +D Sbjct: 1174 KEQALIRKKMAKDTVVVRTYVEDQEFHISSFEE----RLIKEIEYRIIKTTLEELLEEDG 1229 Query: 1312 HQR-SLDLS-GQAFDEAF-AEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTV 1368 ++ ++D+S +A + F + + ++ I+EG + C + Sbjct: 1230 EEKMAVDISESEAVESGFDSRIKNYR---------------------ILEGMGVTFHCKM 1268 Query: 1369 FGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 G P P++ W+K+ + I+ E + + Q S+ I V ED G Y+ N G Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325 Score = 40.4 bits (93), Expect = 0.013 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 11/109 (10%) Query: 159 RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE-SNYGVHTLEIN 217 R++++ + E M V + G+P P + WYKDG I +Y+++ G +L I Sbjct: 1250 RIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE---RYQMDFLQDGRASLRIP 1306 Query: 218 RADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +D Y+A A+N G + + V EP +G P +P Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYV-------EPAAPLGAPTYIP 1348 Score = 40.4 bits (93), Expect = 0.013 Identities = 21/71 (29%), Positives = 32/71 (45%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ +G + V G PDPE W+KN I+ S+ + + I+ VT+EDS Sbjct: 2042 TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2101 Query: 1415 KYSINIKNKYG 1425 + N G Sbjct: 2102 SIMVKAINIAG 2112 Score = 40.4 bits (93), Expect = 0.013 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 18/121 (14%) Query: 1332 QFKAAAFAEKNRG--RLIG--------------GLP-DVVTIMEGKTLNLTCTVFGNPDP 1374 QF+ A+ EK + R++G LP + +I G+ L + V G P P Sbjct: 17910 QFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17969 Query: 1375 EVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 + W K+ + ++ + +V+ E A + IK +D GKY++ N G +++V Sbjct: 17970 NISWVKDGEPLKQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 18028 Query: 1435 V 1435 V Sbjct: 18029 V 18029 Score = 40.0 bits (92), Expect = 0.017 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + ++EG+ L++ P P V W K+ ++++ S+ ++K + K V + D+ Sbjct: 8024 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DA 8082 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y+I ++NK G + V V Sbjct: 8083 GIYTITLENKLGSATASINVKV 8104 Score = 40.0 bits (92), Expect = 0.017 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1344 GRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY-VS 1402 G L L + + G T+ L V G P P++ W K ++ L + + ++ + Sbjct: 13321 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSK--PNVNLRDRIGLDIKSTDFDTF 13378 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 + + V D+GKY + ++N G ++ + V V Sbjct: 13379 LRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411 Score = 40.0 bits (92), Expect = 0.017 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ + + G P P V W K+++++ +S++ + + +TI VT D+GKY + Sbjct: 20914 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKYIL 20972 Query: 1419 NIKNKYGGEKIDVTVSV 1435 I+N G K TVSV Sbjct: 20973 TIENGVGEPK-SSTVSV 20988 Score = 39.7 bits (91), Expect = 0.022 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 27/191 (14%) Query: 1263 NWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQA 1322 +W A + S ++ GGS+ ++ K++GK +E GKD R L Sbjct: 10059 DWTKSSADLEWSPPLKDGGSKVTGYIV----EYKEEGKEEWE--KGKDKEVRGTKLVVTG 10112 Query: 1323 FDE-AFAEFQ--QFKAAAFAEKN--------RGRLIG-------GLPDVVTIMEGKTLNL 1364 E AF +F+ A E + RL+ + D + + G + + Sbjct: 10113 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRI 10172 Query: 1365 TCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKY 1424 V G P P V W N++ L + +++ A SM IK G YS+ KN+ Sbjct: 10173 IAYVSGKPPPTVTWNMNER--TLPQEATIET-TAISSSMVIKNCQRSHQGVYSLLAKNEA 10229 Query: 1425 GGEKIDVTVSV 1435 G K + V V Sbjct: 10230 GERKKTIIVDV 10240 Score = 39.3 bits (90), Expect = 0.028 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + +G + LT + G P P W K QDI S+ + + + + IK DS Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSET-HTELVIKEADRGDS 23830 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y + ++NK G + + + V V Sbjct: 23831 GTYDLVLENKCGKKAVYIKVRV 23852 Score = 39.3 bits (90), Expect = 0.028 Identities = 60/321 (18%), Positives = 118/321 (36%), Gaps = 50/321 (15%) Query: 68 CRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKL- 126 C++ K + ++ E Q+ ++ S + +A Q +S+ A E++ ++ +++++KL Sbjct: 26565 CKLTIKAI--KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLA 26622 Query: 127 -----DKYAIQQMMEDKLAW--ERHTFEERISRAPEILVRLRSHTVWERMSV-------- 171 K I + ++ A E+ E I++ + +R+H + S Sbjct: 26623 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQ 26682 Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 +L V+W +G + + E YR + TL I +A D + ++ Sbjct: 26683 RLVLKANIAGATDVKWVLNGVELTNSEE---YRYGVSGSDQTLTIKQASHRDEGILTCIS 26739 Query: 232 TNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRRE 291 G V + + + D F I P S I E Sbjct: 26740 KTKEGIVKCQYDLTLSKELSDAPAF------ISQPRSQNI------------------NE 26775 Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 G+ V C + P P EW+++++ + S + SL + D G Sbjct: 26776 GQNVLFTCEISGEPS-----PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26830 Query: 352 LYTLRIVSRGGVSDHSAFLFV 372 YT++ + G +A L V Sbjct: 26831 KYTIKAKNFRGQCSATASLMV 26851 Score = 38.9 bits (89), Expect = 0.037 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK---YVSMTIKGVTS 1410 + + G + + G P PE+ W + + + F+ KV+ K Y ++I Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGE------FTDKVQIEKGVNYTQLSIDNCDR 17715 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 D+GKY + ++N G + VTV V + PPQ K Sbjct: 17716 NDAGKYILKLENSSGSKSAFVTVKV------LDTPGPPQNLAVK 17753 Score = 38.5 bits (88), Expect = 0.048 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ G ++L G P P + W K+ ++ SE + K ++++IK E Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK-ITLSIKNAKKEHG 21259 Query: 1414 GKYSINIKNKYGGEKIDVTV 1433 GKY++ + N + +TV Sbjct: 21260 GKYTVILDNAVCRIAVPITV 21279 Score = 38.5 bits (88), Expect = 0.048 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-DSGKYS 1417 G TL L G P P + WF + +Q SE+ +++ Y + +K V + +GKY Sbjct: 24271 GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE-NTEHYTHLVMKNVQRKTHAGKYK 24329 Query: 1418 INIKNKYG 1425 + + N +G Sbjct: 24330 VQLSNVFG 24337 Score = 38.1 bits (87), Expect = 0.063 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 K +Q P QW+K G I E K I S+ + +LEI R D Y+ A Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIY---ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4536 Query: 232 TNAHGQVSTNAAVVV 246 +N +G VS A + V Sbjct: 4537 SNEYGSVSCTATLTV 4551 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQL-SEHFSVKVEQAK----YVSMTIK 1406 D + + G+ +++ V G P P++ W KN+ I+ ++ + E+ ++I Sbjct: 9034 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9093 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSVY 1436 ED G Y++ N+ G +V V VY Sbjct: 9094 KAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D V + G+ L V G P P + W K+ ++++ + +K+ ++ K T Sbjct: 15097 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS-TNLVNKDSTRR 15155 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y++ N G K V V Sbjct: 15156 DSGAYTLTATNPGGFAKHIFNVKV 15179 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSEDS 1413 T++ G+ L + G P P V W K+ ++ L + V E + S +TIK ED Sbjct: 15786 TVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKDACREDV 15843 Query: 1414 GKYSINIKNKYG 1425 G Y + + N G Sbjct: 15844 GHYVVKLTNSAG 15855 Score = 37.0 bits (84), Expect = 0.14 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V + G + L V G P P+V W K D + + V+ + + I T +D Sbjct: 12243 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF--LVIPNSTRDD 12300 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDM 1445 SGKYS+ + N G + + V V V + D+ Sbjct: 12301 SGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12333 Score = 37.0 bits (84), Expect = 0.14 Identities = 16/79 (20%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 ++ G+ L + + G P P + W K+ ++ + +V + +++IK +D G Sbjct: 16868 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGG 16926 Query: 1415 KYSINIKNKYGGEKIDVTV 1433 +Y I + N G + + + Sbjct: 16927 QYGITVANVVGQKTASIEI 16945 Score = 37.0 bits (84), Expect = 0.14 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 907 VEARPGTKEISAGVDEQGNIYLGFDC--QEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 +E P + +I V E+G ++ + C + ++Q TW ++ + E+++I Sbjct: 25193 IEIGPVSGQIMHAVGEEGG-HVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV 25251 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSF 994 + LY+K+ K D GTY V + G SS+ Sbjct: 25252 AILYVKDITKLDDGTYRCKVVNDYGEDSSY 25281 Score = 36.6 bits (83), Expect = 0.18 Identities = 110/564 (19%), Positives = 213/564 (37%), Gaps = 96/564 (17%) Query: 879 QGKTYVFRVRAVNANGVGKP-------SDTSEPVLVEARP--GTKEISAGVDEQGNIYLG 929 +GKT+ ++ V + + + S T++ ++EA P K E+ I L Sbjct: 5252 EGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITL- 5310 Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 C+ D W K EEI ++ I+ G L +K D +D G Y V TD Sbjct: 5311 -KCEVSKDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY-VCDCGTDK 5367 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 ++ ++ RL+ + + + + +EI E PD ++ Sbjct: 5368 TKANVTVEA----RLIKVEKPLYGVEVFVGETAHFEI------------ELSEPDVHGQW 5411 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + + ++ S I D I+ ++ + G + Q + K+ + + + Sbjct: 5412 KLKGQPLTASPDCEIIEDGKKHIL--ILHNCQLGMTGEVSFQAANAKSAANLKVKELPLI 5469 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVL 1169 F T L + + V E+ E + C+V+ K F+WLK Sbjct: 5470 FITPLSDVK---------------------VFEKDEAKFECEVSREPK--TFRWLKG--- 5503 Query: 1170 YETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS--ILEIAGKVYDDMILAM 1227 T+ + +R EL+ KD ++ +K +D + + E K + L + Sbjct: 5504 --TQEITGDDR--FELI------KDGTKHSMVIKSAAFEDEAKYMFEAEDK-HTSGKLII 5552 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAW 1287 + K +PLK + E ++ D ++V W D ++ ++ + + Sbjct: 5553 EGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSM-------- 5604 Query: 1288 LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLI 1347 +D+GK F KD S+D + Q EA + K + Sbjct: 5605 --------QDEGKTHSITF--KD---LSIDDTSQIRVEAMGMSSEAKLTVL--EGDPYFT 5649 Query: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 G L D + + + + L C + D V WFK+ ++I+ S++ +K + K + + +K Sbjct: 5650 GKLQDYTGVEKDEVI-LQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADGKKRM-LILKK 5706 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDV 1431 D G+Y+ + K+D+ Sbjct: 5707 ALKSDIGQYTCDCGTDKTSGKLDI 5730 Score = 36.6 bits (83), Expect = 0.18 Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 24/144 (16%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 +W+++ I ++ KY I V+TL I A DD A Y+ TN G+ +AA + Sbjct: 6299 KWFRNEEAIFDSS---KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANL 6355 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF--RREGETVTLKCTM-- 301 + +EE R V PL D++ +EK VTF + VTLK T Sbjct: 6356 I----VEEEDLRIVE-----PLK--------DIETMEKKSVTFWCKVNRLNVTLKWTKNG 6398 Query: 302 LVTPDLKRVQPRAEWYRDDVLLKE 325 P RV R + Y+ + +K+ Sbjct: 6399 EEVPFDNRVSYRVDKYKHMLTIKD 6422 Score = 36.6 bits (83), Expect = 0.18 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 1370 GNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEK 1428 G P V W K+ Q L E V V +K V S++IK + ED G Y + + N G Sbjct: 19048 GRPQATVNWRKDGQT--LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19105 Query: 1429 IDVTVSV 1435 + +T+ V Sbjct: 19106 VPITIIV 19112 Score = 36.6 bits (83), Expect = 0.18 Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK--YVSMTIKGVTSEDSGKYSINIK 1421 L C V G+P P V W++ ++I +++ ++++ K Y + I VT +D+ Y + Sbjct: 24575 LVCKVTGHPKPIVKWYRQGKEI-IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRAT 24633 Query: 1422 NKYG 1425 N+ G Sbjct: 24634 NQGG 24637 Score = 36.2 bits (82), Expect = 0.24 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V G + + V G P P V W K DQ ++ ++ + + + + I D Sbjct: 14702 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECVRSD 14760 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVY 1436 SG Y + +N G +T+ V+ Sbjct: 14761 SGPYPLTARNIVGEVGDVITIQVH 14784 Score = 36.2 bits (82), Expect = 0.24 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT G+ L+C + G P P++ W++ +++ S + + + + ++T+ ED Sbjct: 24170 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH-TLTVMTEEQEDE 24228 Query: 1414 GKYSINIKNKYG 1425 G Y+ N+ G Sbjct: 24229 GVYTCIATNEVG 24240 Score = 35.4 bits (80), Expect = 0.41 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP + + + E SV V G P P V W K G + YR + +Y Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-----YRYKVSYNKQ 1089 Query: 213 T----LEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 T L I+ DD Y+ V N HG+ S +A+++ Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1126 Score = 35.4 bits (80), Expect = 0.41 Identities = 46/222 (20%), Positives = 81/222 (36%), Gaps = 34/222 (15%) Query: 145 TFEERISRA--PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGK 202 T E ++ R P +++ S E + + V G P P W+ DG I K Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVN-DYTHK 1458 Query: 203 YRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP 262 I+ + G +L I A D+ ++ VA N G+ S + + V +P Sbjct: 1459 VVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKP------- 1510 Query: 263 IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL 322 F+EK +EG + +K P+ P W ++ + Sbjct: 1511 ----------------MFVEKLKNVNIKEGSRLEMKVRATGNPN-----PDIVWLKNSDI 1549 Query: 323 LKESKWTKMFF--GEGQASLSFSHLHKDDEGLYTLRIVSRGG 362 + K+ K+ +G+A+L D YT +++ G Sbjct: 1550 IVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1591 Score = 35.0 bits (79), Expect = 0.53 Identities = 55/234 (23%), Positives = 82/234 (35%), Gaps = 50/234 (21%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V+W+KDG+ I + KY I S V L IN+ DD A YS A Sbjct: 6032 VKWFKDGAEIKKGK---KYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR--------- 6079 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 S M+ + F + E +T+ L C + Sbjct: 6080 ----------------------TSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV--- 6114 Query: 305 PDLKRVQPRAE--WYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR-- 360 +P AE WY+ D + E+ ++ + L + H +D G Y R+ S Sbjct: 6115 -----SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRT 6169 Query: 361 -GGVSDHS-AFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 G V H A F+ L G + C +++ V WK + T ES Sbjct: 6170 DGKVKVHELAAEFISKPQNLEI-LEGEKAEFVC-SISKESFPVQWKRDDKTLES 6221 Score = 34.7 bits (78), Expect = 0.69 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 1/85 (1%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 I G L+ TV G P P++ WF N + S + + + S+ I ED G+ Sbjct: 3593 ISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGE 3651 Query: 1416 YSINIKNKYGGEKIDVTVSVYKHGE 1440 Y+ N YG + + GE Sbjct: 3652 YTCMASNDYGKTICSAYLKINSKGE 3676 Score = 34.7 bits (78), Expect = 0.69 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 175 FTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESN-YGVHTLEINRADFDDTATYSAVATN 233 +TV G P P V W+K+ +C + Y I N G T +N +D+ Y A N Sbjct: 3721 YTVVGEPAPTVTWFKENKQLCTSV---YYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3777 Query: 234 AHGQVSTNAAVVV 246 G+ + A ++V Sbjct: 3778 MLGESTCAAELLV 3790 Score = 34.3 bits (77), Expect = 0.91 Identities = 54/257 (21%), Positives = 107/257 (41%), Gaps = 32/257 (12%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F C+ + +W ++I F++ D +L + ED GTY+ S+ G Sbjct: 3318 FQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG 3377 Query: 990 -VSSSFVLDPEELERL----------MALSNEIKNPTIPLKSEL-----AYEIFDKGRVR 1033 VSS+ L E + ++LS K + K + + + VR Sbjct: 3378 QVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVR 3437 Query: 1034 FWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI-IEMVMDRFSIENEGTYTVQI 1092 F + + P ++ N + + ++ +++TG+ + +++D +S E+ G Y+ + Sbjct: 3438 FHARVSGI-PKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYS-EHAGQYSCKA 3495 Query: 1093 HD--GKAKSQSSLVLIGDAFKTVL-----EEAEFQRKEF------LRKQGPHFAEYLHWD 1139 + G+A ++L + A +++L +E E + KEF ++G H AE Sbjct: 3496 ANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3555 Query: 1140 VTEECEVRLVCKVANTK 1156 + E E+ V TK Sbjct: 3556 INETLELLSESPVYPTK 3572 Score = 33.9 bits (76), Expect = 1.2 Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 1367 TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 TV G P P V WFK ++ + S ++++ + + EDSG Y +N G Sbjct: 3722 TVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3780 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 R + L + VT+++G+ L L+C + N + +V+W K+ + + V ++T Sbjct: 4841 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4898 Query: 1405 IKGVTSEDSGKYSINIKN 1422 I D+G Y++ ++N Sbjct: 4899 INDADDTDAGTYTVTVEN 4916 Score = 33.1 bits (74), Expect = 2.0 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 3/93 (3%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + TV +K+ G PTP V W+KD + Q E+N Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN---SL 15832 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVV 246 L I A +D Y TN+ G+ V+V Sbjct: 15833 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 28/108 (25%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQ--------------------DIQLSEHFSVKV 1395 + G + L ++ G+P P + W K++ ++Q E F + + Sbjct: 8319 VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPL 8378 Query: 1396 EQAKYVSMTIKGVTS--------EDSGKYSINIKNKYGGEKIDVTVSV 1435 Q + + KG + D G Y I ++N +G K TVSV Sbjct: 8379 TQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK-------NDQDIQLSEHFSVKVEQAKYVS 1402 L + + + EG +N+ + G P P + WFK N + + H + K+ + Sbjct: 9750 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9808 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 + I D+G Y+I N G ++ ++V G P + P Sbjct: 9809 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL--GRPGPPVGP 9851 Score = 32.0 bits (71), Expect = 4.5 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G ++ + + G P PEV W K+ +I L +++ ++ + + I D+ Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTES-FTLLIIPECNRYDT 14470 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 GK+ + I+N G + V V V + ++ P K Sbjct: 14471 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK 14509 Score = 32.0 bits (71), Expect = 4.5 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 1364 LTCTVFGNP--DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIK 1421 LTC V + EV W+K+ + ++ + HF + I +T D G+Y I Sbjct: 26363 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 26422 Query: 1422 NKYGGEKIDV 1431 + G K ++ Sbjct: 26423 GEGGTSKTNL 26432 >gi|110349715 titin isoform N2-B [Homo sapiens] Length = 26926 Score = 269 bits (688), Expect = 1e-71 Identities = 229/865 (26%), Positives = 373/865 (43%), Gaps = 101/865 (11%) Query: 153 APEILVRLR---SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 APEI + ++ TV ++L TV G P P + W K ++ Q + IE+ Sbjct: 7190 APEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK---RITIENVP 7246 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 T+ I + DT TY A N G+ + V V L Sbjct: 7247 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV--------------------LDK 7286 Query: 270 MIPYTHFDVQFL--EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK 327 P FD+ + E +T+ + K T V +R W++ +K++ Sbjct: 7287 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE--RRATDSEVWHKLSSTVKDTN 7344 Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAP 383 + + L + E ++ + + GV + A P+ P Sbjct: 7345 FKA------------TKLIPNKEYIFRVAAENMYGVGEPV------QASPITAKYQFDPP 7386 Query: 384 GAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYP 443 G P L+ D +D V +TW P+ SP+ GY+V+R + T+ WV+CN PVK Y Sbjct: 7387 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYR 7446 Query: 444 VTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD 503 V GL + Y FRV A N AG +PS+ ++ + DP+D Sbjct: 7447 VKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID--------------------- 7485 Query: 504 LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVGSGSWQRVNAQ 562 P PP ++ + V L+W P G + Y IE G+ W RV Sbjct: 7486 ------PPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV--A 7537 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 V + ++ + LMEG+ Y FRV + N+ G SEPSE + P+ ++ PS P + Sbjct: 7538 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7597 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 TK + ++W P+ + + Y V+ W+ + + + V LT G Y Sbjct: 7598 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVD-TTVKDTKCTVTPLTEGSLY 7656 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 +FRV A NA+G S+ ++ D + + T P PY + +++ + L W+ PK GG Sbjct: 7657 VFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGR 7716 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PI Y ++K+E W + + V + EG+ +F++ A N AG+G PS+P+ Sbjct: 7717 PIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPT 7776 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 E E T P P P DL + + + WK P +G SP+ GY V+ +W+ Sbjct: 7777 EILSIEDPTSP-PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWM 7835 Query: 861 TVNQTTTANRYLKVSD-LQQGKTYVFRVRAVNANGVGKPSDTSEPVLV---EARP----G 912 VN + KV + + K YV RVRAVNA GV +PS+ SE V+ + +P Sbjct: 7836 RVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE 7895 Query: 913 TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 T +I E+ +I + F + S W K +E+ +R ++ DH +L+ P Sbjct: 7896 THDIIVIEGEKLSIPVPFRAVPVPTVS---WHKDGKEVKASDRLTMK--NDHISAHLEVP 7950 Query: 973 D--KEDLGTYSVSVSDTDGVSSSFV 995 + D G Y++++ + G +++ + Sbjct: 7951 KSVRADAGIYTITLENKLGSATASI 7975 Score = 268 bits (685), Expect = 3e-71 Identities = 209/769 (27%), Positives = 337/769 (43%), Gaps = 83/769 (10%) Query: 272 PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM 331 P DV+ L V + G + L T+ P+ P+ W + D++LK+ K + Sbjct: 7191 PEIFLDVKLLAGLTV---KAGTKIELPATVTGKPE-----PKITWTKADMILKQDKRITI 7242 Query: 332 FFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 +++++ + D G Y + V+ G + + V D PG P Sbjct: 7243 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK-------PGPPAAFDI 7295 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 D + ++TW PP S + Y V+R + W + + + VK + T L + Sbjct: 7296 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNK 7354 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 YIFRV A N G+ P + S A YQ D P Sbjct: 7355 EYIFRVAAENMYGVGEPVQASPITAK----------------------YQFD------PP 7386 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 GPPT + S+I+++ V L+W P G P+ Y++E+ + W R N + V+ Y Sbjct: 7387 GPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN-KMPVKDTTY 7445 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L K Y FRVL+ N G +PS+ T PI +D P PG+ KTSV + Sbjct: 7446 RVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRL 7505 Query: 631 QWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 W +P+H+ + Y ++ GT+ W + + + ++ GL G++Y FRV+AVN Sbjct: 7506 NWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVN 7564 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G SE S+ SD + + L PS P + ++N ++ L W VP+ GGSPI Y ++ Sbjct: 7565 KAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE 7624 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+V K W V+++ K T TV LTEGSLY F++AA N G + ++ + + Sbjct: 7625 KRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD- 7682 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 T PGP Y L +V + + W+ P G P+ Y ++ +E W+ +T Sbjct: 7683 TFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGP 7742 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNI 926 + +V+D+ +G F+VRA N GVG PS+ +E + +E P + + V + G Sbjct: 7743 DCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRK 7802 Query: 927 YLGFDCQ---------------EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 ++ + EM W + D +FK+E Sbjct: 7803 HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG--------VV 7854 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS 1020 PDKE Y + V + + V +P E+ + + PTI L++ Sbjct: 7855 PDKE----YVLRVRAVNAIG---VSEPSEISENVVAKDPDCKPTIDLET 7896 Score = 231 bits (588), Expect = 5e-60 Identities = 228/871 (26%), Positives = 358/871 (41%), Gaps = 147/871 (16%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 TV +V L TV G P P V W KDG+L+ + AE K ++ N + TLE+ + D Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLL-KPAEGIKMAMQRN--LCTLELFSVNRKD 12865 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y+ A N+ G S + V ++P G P + ++ M + ++ Sbjct: 12866 SGDYTITAENSSGSKSATIKLKVL-----DKP----GPPASVKINKM---------YSDR 12907 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 +++ E + T + + +P W ++ S S Sbjct: 12908 AMLSWEPPLEDGGSEITNYIVDKRETSRPN--------------WAQVSATVPITSCSVE 12953 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA------DPLVTGAPGAPMDLQCHDANRD 397 L + E + + ++ GV D +F A DP PG + +D Sbjct: 12954 KLIEGHEYQFRICAENKYGVGDP---VFTEPAIAKNPYDP-----PGRCDPPVISNITKD 13005 Query: 398 YVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRV 457 ++ V+WKPP SP+ GY +++ E NW + N P+ TGL EG Y FRV Sbjct: 13006 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13065 Query: 458 RAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGV 517 A+N AG +PS S A A DP PGPP Sbjct: 13066 TAINKAGPGKPSDASKAAYARDP---------------------------QYPPGPPAFP 13098 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM 576 + +R+ V LSW P G P++ Y +E S +W R N ++ R+ V LM Sbjct: 13099 KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLM 13158 Query: 577 EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV------- 629 E Y FRV + N+ G S+PS++ +D+ + P L + KT ++ Sbjct: 13159 EDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGE---LDADLRKTLILRAGVTMR 13215 Query: 630 ------------VQWDRPK-HEEDLLGYYVDCCVAGTNL-WEPCNHKPIGYNRFVVHGLT 675 + W +P + D +G + T L E N G Sbjct: 13216 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG---------- 13265 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +YI ++ N+ G E + V+KV L P P +T+ S + W+ P Sbjct: 13266 ---KYILTLE--NSCGKKEYTI---VVKV---LDTPGPPVNVTVKEISKDSAYVTWEPPI 13314 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGSPI+ Y + KR+ K+W V + SK T V L EG Y F++ A N GIG+ Sbjct: 13315 IDGGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGD 13373 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + K PGP DL V +S + WK P G S + GY VDF E+ Sbjct: 13374 PGETRDAVKAS----QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEE 13429 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKE 915 +W V ++ + K DL +GK Y FRV A N NG G PS+ + V AR Sbjct: 13430 -NKWQRVMKSLSLQYSAK--DLTEGKEYTFRVSAENENGEGTPSE----ITVVARDDV-- 13480 Query: 916 ISAGVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDH 964 ++ +D +G L + +E ++ A +W K + ++ D R +E+ + Sbjct: 13481 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13540 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + L + + K D G Y++++ + G + Sbjct: 13541 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13571 Score = 226 bits (575), Expect = 2e-58 Identities = 233/937 (24%), Positives = 390/937 (41%), Gaps = 106/937 (11%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E++S+ + F + P P V W+KDG + + +++++ LE+ ++ D Sbjct: 7905 EKLSIPVPF--RAVPVPTVSWHKDGK---EVKASDRLTMKNDHISAHLEVPKSVRADAGI 7959 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGV 286 Y+ N G + + V V IGLP P + K Sbjct: 7960 YTITLENKLGSATASINVKV----------------IGLPG----PCKDIKASDITKSSC 7999 Query: 287 TFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLH 346 E TP L V R E R + + GE + S + L Sbjct: 8000 KLTWEPPEFDGG-----TPILHYVLERREAGR-------RTYIPVMSGENKLSWTVKDLI 8047 Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANRDYVIVT 402 + E + ++ V++ G + ++ +P++ P P+D++ H+ + + +T Sbjct: 8048 PNGEYFFRVKAVNKVGGGE-----YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8102 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 WKPP S +MGY +++ G W +CN+ V I Y GL EG+ Y FRVRA N+ Sbjct: 8103 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8162 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPP----TGVH 518 AGIS PSR + A+DP+D + V L E+ D++ DA + G P T + Sbjct: 8163 AGISEPSRATPPTKAVDPIDAPK---VILRTSLEVK-RGDEIALDASISGSPYPTITWIK 8218 Query: 519 ASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSP-RYAVFDLME 577 + + P R + + E V+ QR++ + + + V D + Sbjct: 8219 DENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT--QRLSIDNSKKGESQLRVRDSLR 8276 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 ++ + N HG+++ S + P P + KTSV+ +W+ P Sbjct: 8277 PDHGLYMIKVENDHGIAKAPCTVSVLDT------PGPPINFVFEDIRKTSVLCKWEPPLD 8330 Query: 638 E--EDLLGYYVDCCVAGTNLWEPCNH-----KPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + +++ Y ++ + +P + + + ++ V L G++Y+FRV+A N Sbjct: 8331 DGGSEIINYTLE----KKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8386 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKR 750 G ++ + P P + + +SM + W PK GSPILGY+L+KR Sbjct: 8387 GPGPPCVSKPLV-AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKR 8444 Query: 751 EVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTM 810 EV+ +W VN S VDGL EG Y F++ A N AG G+ S PS+ K + Sbjct: 8445 EVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP-KTAHDPI 8503 Query: 811 PEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR 870 PGP + T++ + W+ P ++G + GYFVD + EW + R Sbjct: 8504 SPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVR 8562 Query: 871 YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 V ++++G Y RV AVNA G G P +T +PV V + V +G I + Sbjct: 8563 QYTVKEIREGADYKLRVSAVNAAGEGPPGET-QPVTVAEPQEPPAVELDVSVKGGIQIMA 8621 Query: 931 DCQEMTDA-------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 A W K E+ D +R I+ VG S+L +K+ ++D G Y ++ Sbjct: 8622 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8680 Query: 984 VSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 +++ G S F E+ ++ P + LK + K + W E Sbjct: 8681 ATNSCG--SKFAAARVEV-------FDVPGPVLDLKPVVTNR---KMCLLNWSDPEDDGG 8728 Query: 1044 DASYRFIINDREV------SDSEIHRIKCDKATGIIE 1074 FII ++ E R KCD TG++E Sbjct: 8729 SEITGFIIERKDAKMHTWRQPIETERSKCD-ITGLLE 8764 Score = 218 bits (554), Expect = 4e-56 Identities = 194/813 (23%), Positives = 330/813 (40%), Gaps = 104/813 (12%) Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPM 387 WT + SL + L + +E ++ + V++ GV + V +P V PG P Sbjct: 17269 WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVL--PGPPK 17326 Query: 388 DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGL 447 L+ + +D + V W P++ S ++GY V++ + W++CN + + VTGL Sbjct: 17327 SLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGL 17386 Query: 448 FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD 507 E Y FRV A N+AG+ PS + A DP+ Sbjct: 17387 TEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFK------------------------ 17422 Query: 508 AQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566 PGPPT H + ++N + L+W P G + L Y +E WQ V QT +R Sbjct: 17423 ---PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLR 17479 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD----------------VTV 610 R+ + L E + Y RV + N+ GL E + + ++ +D + V Sbjct: 17480 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 17539 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 R+ + + + W R + G + D K + Y + Sbjct: 17540 RAGGSARIHIPFKGRPTPEITWSREE------GEFTDKVQI---------EKGVNYTQLS 17584 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 + + + +K N+ G +S + V+ L P P + + S L Sbjct: 17585 IDNCDRNDAGKYILKLENSSG-----SKSAFVTVKV-LDTPGPPQNLAVKEVRKDSAFLV 17638 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W+ P GG+ + Y +DKRE K + V+S SK T V+ LTEG++Y F++ A N Sbjct: 17639 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAENE 17697 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 G+G P + + K P P +T +V TS ++W+ P + G S V GY V+ Sbjct: 17698 FGVGVPVETVDAVKAAE----PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17753 Query: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE-- 908 + + +W V ++ N V+ L G+ Y FRV+A N G P PV+ + Sbjct: 17754 MQPKGTEKWSIVAESKVCNAV--VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17811 Query: 909 -ARPGTK------EISAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIET 960 +P K I AG D + I +G +W K E + R +E Sbjct: 17812 TIQPSLKLPFNTYSIQAGEDLKIEIPVIG------RPRPNISWVKDGEPLKQTTRVNVEE 17865 Query: 961 VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTI-PLK 1019 + L++K +K+D G Y+V+ +++ G ++ E L + E P + P++ Sbjct: 17866 TATSTVLHIKEGNKDDFGKYTVTATNSAGTAT---------ENLSVIVLEKPGPPVGPVR 17916 Query: 1020 SELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDR 1079 + E+ V W + +I+ R+ + + H + A I++ + Sbjct: 17917 FD---EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 17973 Query: 1080 FSIENEGTYTVQIHDGK-AKSQSSLVLIGDAFK 1111 E + + GK A S V++ FK Sbjct: 17974 TGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 18006 Score = 216 bits (551), Expect = 1e-55 Identities = 213/874 (24%), Positives = 350/874 (40%), Gaps = 152/874 (17%) Query: 164 TVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 T+ S++L +V G P PV+ W K G + A I++ L +++ + D Sbjct: 22960 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-----IDTTESYSLLIVDKVNRYD 23014 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGD-------EEPFRSVGLPIGLP-LSSMIPYTH 275 Y+ A N G+ S V V G E SV + +P + P + Sbjct: 23015 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23074 Query: 276 FDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE 335 + V+ E F+ TVT KC+ + V+ ++R +L E+ +G Sbjct: 23075 YIVEKREAAMRAFK----TVTTKCSKTLYRISGLVEGTMYYFR---VLPEN-----IYGI 23122 Query: 336 GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDAN 395 G+ + + LV+ P P L+ D Sbjct: 23123 GEPCETSDAV--------------------------------LVSEVPLVPAKLEVVDVT 23150 Query: 396 RDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIF 455 + V + W+ P S + GY ++ C+ GT W++ + ++ VT L EG Y+F Sbjct: 23151 KSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLF 23210 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP-GPP 514 R+RA N G+S P + V A+ DLR L + L + I+ VP G P Sbjct: 23211 RIRAQNEKGVSEPR---ETVTAVTVQDLRVLPTIDLSTMPQKTIH---------VPAGRP 23258 Query: 515 TGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 + R SW +F + S +RV +T + + + + Sbjct: 23259 VELVIPIAGRPPPAASW------------FFAGSKLRES---ERVTVETHTKVAKLTIRE 23303 Query: 575 LMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 + + + N G L +P T PI+ ++ Sbjct: 23304 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA-------------- 23349 Query: 625 KTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIF 682 TS+ + W+ P+ + L GY V+ A W P + + + F LT G +Y+F Sbjct: 23350 -TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVF 23407 Query: 683 RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 RV A N G+ Q S+VI+ ++++ +P P + + + MTL W P+ GGS + Sbjct: 23408 RVAATNRFGIGSYLQ-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23466 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 GY ++++EV W VN P T GLTEG YE ++ A+N G G+PS PS+ Sbjct: 23467 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23526 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P PG + + TS+ + W P G S V+GY ++ ++ D EW Sbjct: 23527 IVAMDPIAP-PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKC 23585 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 N T T R ++ L QG Y FRV A NA G G+P++ PGT +++ ++ Sbjct: 23586 NTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLE- 23635 Query: 923 QGNIYLGFDCQEMTDASQFT---------------------WCKSYEEISDDERFKIETV 961 Y ++ E F W K ++IS +R I T Sbjct: 23636 ----YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATS 23689 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 H++L +K D+ D GTY + + + G + ++ Sbjct: 23690 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23723 Score = 216 bits (549), Expect = 2e-55 Identities = 172/613 (28%), Positives = 259/613 (42%), Gaps = 54/613 (8%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 ++ P +P A W D +L+ KM A L S + D+G+YTL++ +R Sbjct: 6917 ILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR- 6975 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 V S + D V P AP +L+ D +D V +TW+PP+ SP+ GY V++ Sbjct: 6976 -VKTISG-----EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEK 7029 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 EV W + D V ++ V L +G+ Y+F+V A N G P+ V + V P Sbjct: 7030 REVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTP- 7087 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 A VP PP V + + N + L+W+PP G Sbjct: 7088 --------------------------ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSR 7121 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ GS W V V + V L EGK Y +RV + NR G S+PS T Sbjct: 7122 IKGYIVERCPRGSDKW--VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7179 Query: 601 SPIQAQDVTVVPS--APGRVLASRNTKTSVVVQWDRP---KHEEDLLGYYVDCCVAGTNL 655 IQA D P ++LA K ++ K E + D + Sbjct: 7180 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7239 Query: 656 WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY 715 N V + YI ++AVN G + E +V L P P Sbjct: 7240 ITIENVPKKSTVTIVDSKRSDTGTYI--IEAVNVCGRATAVVEVNV------LDKPGPPA 7291 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL 775 + + S L W P+ GGS I Y +++R + WH++ SS K T L Sbjct: 7292 AFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL-SSTVKDTNFKATKL 7350 Query: 776 TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKA 835 Y F++AA N+ G+GEP S + PGP L ++ ++ + W Sbjct: 7351 IPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTLTWCE 7408 Query: 836 PVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 P G SP++GY+V+ + D +W+ N+ + +V L K Y FRV A N G Sbjct: 7409 PDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGP 7468 Query: 896 GKPSDTSEPVLVE 908 GKPS ++EP+L++ Sbjct: 7469 GKPSKSTEPILIK 7481 Score = 207 bits (526), Expect = 8e-53 Identities = 199/842 (23%), Positives = 329/842 (39%), Gaps = 127/842 (15%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHG 236 ++G P P V W KDG + + A + I+S TL + D Y +N G Sbjct: 18234 IRGKPIPDVVWSKDGKELEETA--ARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18291 Query: 237 QVSTNAAVVVRRFRGDEE-PFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETV 295 S V V G E P + G+ Sbjct: 18292 TKSIPITVKVLDRPGPPEGPLKVTGV---------------------------------T 18318 Query: 296 TLKCTMLVTPDLKRVQPRAEWYRDDVLLKES----KWTKMFFGEGQASLSFSHLHKDDEG 351 KC + P L+ Y ++ K WT++ + + L +E Sbjct: 18319 AEKCYLAWNPPLQDGGANISHY---IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEY 18375 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 ++ + V++ G+ + V +P PG P + +D ++VTW P Sbjct: 18376 IFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITKDSMVVTWARPVDDGG 18433 Query: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRV 471 + + GY +++ + W +CN + + VTGL EG SY FRV A N+AG+ PS Sbjct: 18434 TEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEP 18493 Query: 472 SDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW 531 S A D A+Y PGPP+ ++ SR+ V L+W Sbjct: 18494 SVFYRACD------------------ALYP---------PGPPSNPKVTDTSRSSVSLAW 18526 Query: 532 EPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANR 590 P G P+ Y +E + W T ++ ++ V L E Y FR+ + N Sbjct: 18527 SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINS 18586 Query: 591 HGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTKTSVVVQWDR 634 G+ EP+ + + AQ+ V + SA R+ + + V+W++ Sbjct: 18587 EGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK 18646 Query: 635 PKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 E +L V + + V+ +T + + + N Sbjct: 18647 A---EGILTDRAQIEVTSS------------FTMLVIDNVTRFDSGRYNLTLEN------ 18685 Query: 695 NSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 NS L PS P +T+ S+TL W+ P GG+ I Y ++KRE Sbjct: 18686 NSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 18745 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 K + + ++ +K T ++ L EG Y F++ A N GIG P++ +E K +P PG Sbjct: 18746 KAYATITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLP-PG 18803 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 +T +V + + W+ P G S ++GY V+ + + + +W T Q T + Sbjct: 18804 ---RVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE--ATI 18858 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL---VEARPGTK----EISAGVDEQGNIY 927 S L G+ YVFRV AVN G P PV+ +E +P + + EQ I Sbjct: 18859 SGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKID 18918 Query: 928 LGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 + F + + W K + + + R + + + L +K KED+GTY + VS++ Sbjct: 18919 VPFKGRPQATVN---WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 18975 Query: 988 DG 989 G Sbjct: 18976 AG 18977 Score = 206 bits (525), Expect = 1e-52 Identities = 201/762 (26%), Positives = 307/762 (40%), Gaps = 95/762 (12%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + ++++ +K+ V G P P + W KDG + Q + +E Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT---RVNVEETATSTV 17871 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I + DD Y+ ATN+ G + N +V+V E+P G P+G + + Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVL-----EKP----GPPVG-----PVRF 17917 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 F V E T C + KR W+ + Sbjct: 17918 DEVSADF-----VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATV---------- 17962 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCH 392 + ++ + L E + + +R G S V P G PG P Sbjct: 17963 --ARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VT 18017 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 ++D ++V W P + ++GY +++ E + WV+ N P++ K+ TGL EG Sbjct: 18018 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 18077 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y F+V A N GI +PS+VS+ A DP D Sbjct: 18078 YEFKVSAENIVGIGKPSKVSECFVARDPCD------------------------------ 18107 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYA 571 PP A I+RN V L W+ P G + Y +EK + G W + + T V + Sbjct: 18108 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TNVLETEFT 18166 Query: 572 VFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 V L+E + Y FRV++ N G SEPS+ + I A+D AP L + VV Sbjct: 18167 VSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEI---DAPNASLDPKYKDVIVVH 18223 Query: 631 QWDRPKHEEDLLGYYVDCCV---AGTNLWEPCNH----KPIGYNRFVVHGL--TTGEQYI 681 + E D+ G + V G L E I VV T G QYI Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGS 740 ++ V +S I V+ L P P G + + L W P GG+ Sbjct: 18284 LKLSNVGGT-------KSIPITVK-VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18335 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I Y ++KRE +W +V S+ + V L G+ Y F++ AVN GIGEP + Sbjct: 18336 NISHYIIEKRETSRLSWTQV-STEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESG 18394 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 C + PGP + S+V+ W PV G + + GY ++ R+++ W Sbjct: 18395 PVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18452 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 N+ T + L+V+ L +G +Y FRV A NA GVG+PS+ S Sbjct: 18453 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494 Score = 206 bits (525), Expect = 1e-52 Identities = 205/865 (23%), Positives = 323/865 (37%), Gaps = 151/865 (17%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 S+++ VQG P P V W+KDG + + I G +L + A D Y+ Sbjct: 21478 SLRIKALVQGRPVPRVTWFKDG---VEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTV 21534 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEE-PFRSVGLP-------IGLPLSS-MIPYTHFDVQF 280 A NA G V V+ G P R + PL+ P TH+ ++ Sbjct: 21535 EAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEK 21594 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 E T R + KC +K + +R + K FG G+ Sbjct: 21595 RE----TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNK--------FGVGRPL- 21641 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTG----APGAPMDLQCHDANR 396 D+DP+V P AP + + Sbjct: 21642 ---------------------------------DSDPVVAQIQYTVPDAPGIPEPSNITG 21668 Query: 397 DYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQC-NDAPVKICKYPVTGLFEGRSYIF 455 + + +TW P + S + Y ++R E + WV+ + P+ ++ VTGL EG Y F Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 21728 Query: 456 RVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPT 515 V A N+AG+ S +S + +P++ PGPPT Sbjct: 21729 HVMAENAAGVGPASGISRLIKCREPVN---------------------------PPGPPT 21761 Query: 516 GVHASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFD 574 V ++ S+ V L W P G + + Y IE G W +VNA+ V++ RY V D Sbjct: 21762 VVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT-RYTVTD 21820 Query: 575 LMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS----------------APGRV 618 L G+ Y FRV + N G + E+T I+A D P A R+ Sbjct: 21821 LQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRL 21880 Query: 619 LASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 + + + W +P L T E CN G V + + Sbjct: 21881 FIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSK 21940 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 F VK L P P IT + S TL W P G Sbjct: 21941 SITFTVKV---------------------LDTPGPPGPITFKDVTRGSATLMWDAPLLDG 21979 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+ I Y ++KRE ++W ++ ++ I V+ L EG Y F+++AVN G+GEP + Sbjct: 21980 GARIHHYVVEKREASRRSWQVISEKCTRQ-IFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22038 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E +P P L + +S V+ W P + G S ++GY ++ R++ + Sbjct: 22039 MPEPIVATE----QPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22094 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W+ T V L + Y FRV+A N G +P + V+++ +I Sbjct: 22095 WVEAGHTKQLT--FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE----PQIEP 22148 Query: 919 GVDEQGNIYLGFDCQEMTD-----------ASQFTWCKSYEEISDDERFKIETVGDHSKL 967 D G C+ + A + TW + + +R I T D + L Sbjct: 22149 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTL 22208 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSS 992 +K+ + D G Y +++ +T GV + Sbjct: 22209 TVKDSMRGDSGRYFLTLENTAGVKT 22233 Score = 206 bits (523), Expect = 2e-52 Identities = 163/604 (26%), Positives = 252/604 (41%), Gaps = 58/604 (9%) Query: 311 QPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 +P+ W++D+ + E T + +L + D G Y +V F Sbjct: 10350 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC--VVVENSTGSRKGFC 10407 Query: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 V D G P P+ + +DY++++WKPP S + Y +++ EVG + W+ Sbjct: 10408 QVNVVDR--PGPPVGPVSFD--EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 10463 Query: 431 QCNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAV 489 A K CK V+ L EG+ YIFR+ A N GIS P VSD++ A D Sbjct: 10464 PVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL-VSDSMKAKDRF-------- 10512 Query: 490 HLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKS 549 +VP P +E++++ +++W P GK Y +EK Sbjct: 10513 -------------------RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR 10553 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W RV ++ V DL+EG Y FRV + N G+ +PS + P+ A+D Sbjct: 10554 ETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI 10613 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 PS P A T SV + W P+H+ +LGY V+ G W NH P Sbjct: 10614 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 10673 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 ++ V GL G+ Y FRV AVNA G S+ + + + V+ L P + Sbjct: 10674 ETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHI 10733 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 + ++ G P K + PT +D GS E + Sbjct: 10734 KVGDTLRLSAIIKGVPFPKVTWKKED------------RDAPTKARIDVTPVGSKLEIRN 10781 Query: 786 AAVNLAGI----GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 AA GI E S+ + + +PGP DL E+R S + WK P+ G Sbjct: 10782 AAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGG 10841 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y V+ R+ + +W ++ T+ + L +G Y+FRV A N G G +T Sbjct: 10842 SVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGPFVET 10900 Query: 902 SEPV 905 +P+ Sbjct: 10901 PKPI 10904 Score = 204 bits (520), Expect = 4e-52 Identities = 208/851 (24%), Positives = 344/851 (40%), Gaps = 108/851 (12%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLE------INRADFDDT 224 +++ ++G PTP W DG +A + G + I + + T E I T Sbjct: 9331 IRIPAVIKGRPTPKSSWEFDGKAK-KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9389 Query: 225 ATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF 284 YS A N GQ + N V V G + + + G Sbjct: 9390 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRG-------------------- 9429 Query: 285 GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSH 344 + L M PD + + + WTK+ G + Sbjct: 9430 ---------SCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPD 9477 Query: 345 LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTW 403 L + + + +R +R G+ + A DP+ P P+ L+ ++ V ++W Sbjct: 9478 LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYP--PDPPIKLKIGLITKNTVHLSW 9535 Query: 404 KPPNTTTESPVMGYFVDRCE---VGTNN--WVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 KPP SPV Y V+ GT W QCN V+ ++ V L EG Y FRV+ Sbjct: 9536 KPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVK 9595 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGD--AQVPGPPTG 516 AVN+AG+S+PS A + P D +R KE ++ + A++ G P Sbjct: 9596 AVNAAGVSKPS------ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVP-- 9647 Query: 517 VHASEISRNYVVLSW---EPPTPRGKDPLMY--FIEKSVVGSGSWQRVNAQTAVRSPRYA 571 + L+W P P K+P++Y + K VV + + Y Sbjct: 9648 ---------FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT 9698 Query: 572 VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 + + + + N L P PI+ + V+ + + Sbjct: 9699 I-TAVNNLGTASKEMRLNV--LGRPGPPVGPIKFESVSA---------------DQMTLS 9740 Query: 632 WDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 W PK + + Y ++ A W + +P + + L G +Y+FR+ A N Sbjct: 9741 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNK 9799 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 G+ E +S+ + +VP P T+ + +SMT+ W+ P++ GGSP+ GY+L+ Sbjct: 9800 YGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM 9858 Query: 750 REVHHKNWHEVNSSPSKPTIL----TVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++ K W VN P K L V GL EGS Y+F++ A+N AG+G S PS+ Sbjct: 9859 KDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 9918 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P PGP + + +S + W P+ G S V+GY V+++EE EW Sbjct: 9919 RDPIAP-PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 9976 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--PGTKEISAGVDEQ 923 L V+ L++G Y FRVRAVN G+G+P + ++ + ++ R ++ A V ++ Sbjct: 9977 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDR 10036 Query: 924 GNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLG 978 ++ G + + S TW + E + + IET S + +KN + G Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQG 10094 Query: 979 TYSVSVSDTDG 989 YS+ + G Sbjct: 10095 VYSLLAKNEAG 10105 Score = 203 bits (516), Expect = 1e-51 Identities = 211/854 (24%), Positives = 339/854 (39%), Gaps = 152/854 (17%) Query: 177 VQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFD-----------DTA 225 V G P P ++W KDG + G LEI ADF D+ Sbjct: 14988 VSGRPPPTMEWSKDGKEL--------------EGTAKLEIKIADFSTNLVNKDSTRRDSG 15033 Query: 226 TYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFG 285 Y+ ATN G V V G E PL+ Sbjct: 15034 AYTLTATNPGGFAKHIFNVKVLDRPGPPEG----------PLA----------------- 15066 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESK---WTKMFFGEGQASLSF 342 VT E + KC + P L + + Y V +E+ WT + L Sbjct: 15067 VT-----EVTSEKCVLSWFPPLDDGGAKIDHYI--VQKRETSRLAWTNVASEVQVTKLKV 15119 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + L K +E ++ + V++ GV + V +P G P P + + +D ++V Sbjct: 15120 TKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY--GPPDPPKNPEVTTITKDSMVVC 15177 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P++ S ++ Y V+R + W++CN + +Y V+GL EG Y FR+ A N+ Sbjct: 15178 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15237 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AGIS PS S A D +++ PGPP + Sbjct: 15238 AGISAPSPTSPFYKACD------------------TVFK---------PGPPGNPRVLDT 15270 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 SR+ + ++W P G + Y +E ++ WQ V +++ Y + L E + Y Sbjct: 15271 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15330 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQD----------------VTVVPSAPGRVLASRNTK 625 R+ + N GL EP+ + +A+D VT+ R+ + Sbjct: 15331 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 15390 Query: 626 TSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685 + V+W R H E L ++ + T L NRF +YI V+ Sbjct: 15391 PAPEVKWARD-HGESLDKASIESTSSYTLLIVG------NVNRF------DSGKYILTVE 15437 Query: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 + + +S + V+ L P P + + S+TL W P GGS I Y Sbjct: 15438 -------NSSGSKSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNY 15489 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 ++KRE K + V ++ K T VD L EG Y F++ A N GIG P++ +E K Sbjct: 15490 IVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 15548 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 +P PG +T +V S+ + W+ P + G S + GY V+ + + + +W T Sbjct: 15549 SERPLP-PGK---ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--A 15602 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---------GTKEI 916 T ++ L QG+ Y FRV A N G+ P S PV+ + T + Sbjct: 15603 TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV 15662 Query: 917 SAGVDEQGNI-YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKE 975 AG D + ++ ++G TW K + R E+ ++S L +K+ +E Sbjct: 15663 LAGEDLKVDVPFIG------RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15716 Query: 976 DLGTYSVSVSDTDG 989 D+G Y V ++++ G Sbjct: 15717 DVGHYVVKLTNSAG 15730 Score = 200 bits (508), Expect = 1e-50 Identities = 212/862 (24%), Positives = 330/862 (38%), Gaps = 118/862 (13%) Query: 165 VWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH----TLEINRAD 220 V E +V + ++G P P + W+K EP Y N V TL I ++ Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9690 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQF 280 DT Y+ A N G S + V G P+G P+ F+ Sbjct: 9691 RSDTGLYTITAVNNLGTASKEMRLNV---------LGRPGPPVG-PIK-------FESVS 9733 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASL 340 ++ +++ + K T V KR R W KE +T EG Sbjct: 9734 ADQMTLSWFPPKDDGGSKITNYVIE--KREANRKTWVHVSSEPKECTYTIPKLLEGHE-- 9789 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 Y RI+++ + + PGAP R+ + Sbjct: 9790 ------------YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMT 9837 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC----KYPVTGLFEGRSYIFR 456 V W+ P SPV GY+++ + + W + N P+K Y VTGL EG Y FR Sbjct: 9838 VNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 9897 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 V A+N+AG+ S SD A DP+ PGPP Sbjct: 9898 VYAINAAGVGPASLPSDPATARDPI---------------------------APPGPPFP 9930 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDL 575 ++ +++ L W PP G + Y +E G W++ VR + V L Sbjct: 9931 -KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GKDKEVRGTKLVVTGL 9988 Query: 576 MEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--------------APG--RVL 619 EG Y FRV + N G+ EP E+T I+ +D V P A G R++ Sbjct: 9989 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10048 Query: 620 ASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 A + K V W+ + ++ + + + C Q Sbjct: 10049 AYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS---------------HQ 10093 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 ++ + A N G + + DV+ V + P + +T +C L W P+ GG Sbjct: 10094 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCK-----LTWFSPEDDGG 10148 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPI Y ++KRE + W V + ++ TV GL +G Y F+IAA N G+G + Sbjct: 10149 SPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSIGMGPFVET 10207 Query: 800 SEHFKC-EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 SE E T+PE DL EV ++ + W P Y G S + Y ++ R + Sbjct: 10208 SEALVIREPITVPERPE--DLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10265 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 + V +R V L++G TY +RV AVN G GKPS ++P+ + + Sbjct: 10266 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10325 Query: 919 GVDEQGNIYLGFDCQEMTDA------SQFTWCKSYEEISDDERFKIETVGDHSKLYLKNP 972 ++ I +G + +T + +W K ++ +D+R I+T L Sbjct: 10326 DFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 10384 Query: 973 DKEDLGTYSVSVSDTDGVSSSF 994 + D G Y V V ++ G F Sbjct: 10385 KRSDSGKYCVVVENSTGSRKGF 10406 Score = 199 bits (506), Expect = 2e-50 Identities = 202/839 (24%), Positives = 329/839 (39%), Gaps = 101/839 (12%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +V+ ++G P P +W DGS I Y +E++ L I DT Y Sbjct: 11030 TVRFPAIIRGVPVPTAKWTTDGSEI---KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 +NA G + + V G P G P DV Sbjct: 11087 TVSNAAGSKTVAVHLTVLDVPGP---------PTG-------PINILDVT---------- 11120 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 E T++ + P P + + ++ W + G + L HL K Sbjct: 11121 PEHMTISWQ-----PPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11175 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVT----GAPGAPMDLQCHDANRDYVIVTWKP 405 E ++ +R ++ GV D+ P V P P D + V+W Sbjct: 11176 EYVFRVRAENKIGVGPPL------DSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTL 11229 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + SP+ GY+++R EV T WV+ N P+ K+ VTGL+EG +Y FRV A N AG+ Sbjct: 11230 PKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGL 11288 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 S+PS SD + A P+ + PGPP + SR Sbjct: 11289 SKPSPSSDPIKACRPI---------------------------KPPGPPINPKLKDKSRE 11321 Query: 526 YVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 L W P G P++ Y +E G+ W R+N +R + V L+EG Y FR Sbjct: 11322 TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFR 11381 Query: 585 VLSANRHGLSEPSEITSPIQAQDVTVVPSAP-----GRVLASRNTKTSVVVQWDRPKHEE 639 + +AN G EP E+ + A+D+ P V+ R +T ++ + + E Sbjct: 11382 IKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEP 11441 Query: 640 DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQES 699 D+ + + P + +YI ++A S ++Q S Sbjct: 11442 DITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI-----ISAKNSSGHAQGS 11496 Query: 700 DVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHE 759 ++ V L P + + N + T+ W+ P +GGS I + ++ R+ + K W Sbjct: 11497 AIVNV---LDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSI 11553 Query: 760 VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDL 819 V S +K I L + Y F++ A N G+G P+ ++ + PG +L Sbjct: 11554 VASDVTKRLIKA--NLLANNEYYFRVCAENKVGVG-PTIETKTPILAINPIDRPGEPENL 11610 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + T + + W+ P Y G SP Y V+ R + + +W V++ + + V + Sbjct: 11611 HIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVE 11670 Query: 880 GKTYVFRVRAVNANG---------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGF 930 + Y FRV+ N G V D +PVL G + AG + + G Sbjct: 11671 NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG--DTIRLEAGV 11728 Query: 931 DCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + + + +T K +++ R KI+T D SK L + D G Y V+ ++T G Sbjct: 11729 RGKPFPEVA-WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786 Score = 198 bits (503), Expect = 4e-50 Identities = 178/670 (26%), Positives = 280/670 (41%), Gaps = 68/670 (10%) Query: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313 EP S G PI + P DV+F + V + GE + + + P P Sbjct: 19273 EPSESTG-PIIVKDDVEPPRVMMDVKFRDVIVV---KAGEVLKINADIAGRP-----LPV 19323 Query: 314 AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W +D + ++E T++ + L+ + D G Y L + + G + V Sbjct: 19324 ISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 19383 Query: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433 D G P P+++ A + ++W P + + Y V++ E W C Sbjct: 19384 DK----PGPPAGPLEINGLTAEK--CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC- 19436 Query: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493 + +++ VT L +G YIFRV VN G+ P S A+ ALDP Sbjct: 19437 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKALDPF------------ 19483 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVG 552 VP PPT + + +++ + L W P G + Y IE+ Sbjct: 19484 ---------------TVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19528 Query: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612 S W RVN + V R L EG Y +RV + N GLS PSE + I+A+D +P Sbjct: 19529 SLRWVRVN-KKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19587 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 S P + + KT++ + W +P + + GY V+ + W+ G + Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19646 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVP----SHPYGITLLNCDGHS 726 + GLTTG +Y+FRVK+VN VG S+ S SD + P TL+ G S Sbjct: 19647 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19706 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 T+ VP G P+ K + + V+++ S+ T LT++ ++ + Sbjct: 19707 FTM--TVP--FRGRPVPNVLWSKPDTDLRTRAYVDTTDSR-TSLTIENANRNDSGKYTLT 19761 Query: 787 AVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSG 846 N+ + + PGP ++T +V S V+ W P G +PV Sbjct: 19762 IQNVLS-------AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKN 19814 Query: 847 YFVDFREEDAGEWITVNQTTTANRY-LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE W++V T NR KV++LQ+G Y FRV N GVG P++T E V Sbjct: 19815 YHIEKREASKKAWVSV--TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19872 Query: 906 LVEARPGTKE 915 + +P E Sbjct: 19873 KITEKPSPPE 19882 Score = 196 bits (497), Expect = 2e-49 Identities = 206/843 (24%), Positives = 341/843 (40%), Gaps = 125/843 (14%) Query: 170 SVKLCFTVQGFPTPVVQWYKD------GSLICQAAEPGKYRIESNYGVHTLEINRADFDD 223 SVKL + G P P ++WYKD +L+C +E+ + ++ I AD + Sbjct: 20392 SVKLRAGISGKPAPTIEWYKDDKELQTNALVC---------VENTTDLASILIKDADRLN 20442 Query: 224 TATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEK 283 + Y NA G S V + G P G P+ F EK Sbjct: 20443 SGCYELKLRNAMGSASATIRVQILDKPG----------PPGGPIE-------FKTVTAEK 20485 Query: 284 FGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFS 343 + +R + K T + KR R W L+E ++ + Sbjct: 20486 ITLLWRPPADDGGAKITHYIVE--KRETSRVVWSMVSEHLEE------------CIITTT 20531 Query: 344 HLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-GAPGAPMDLQCHDANRDYVIVT 402 + K +E ++ +R V++ G+ + V + VT G PG P + ++ + V Sbjct: 20532 KIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKITKNSMTVV 20588 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W P S + GYF+++ + + W + ++ + VTGL E Y +RV AVN+ Sbjct: 20589 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 20648 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 AG S S+ A DP+D PGPP + ++ Sbjct: 20649 AGQGPFSEPSEFYKAADPID---------------------------PPGPPAKIRIADS 20681 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 +++ + L W P G + Y +E W V+ + VR+ Y V +L G +Y Sbjct: 20682 TKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNY 20741 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP------GRVLASRNTKTSVVVQWD-R 634 FRV + N G EP E+ P+QA+D+ P V+A V++ + R Sbjct: 20742 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGR 20801 Query: 635 P------KHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 P + +E LG + T+ + N TG+ YI ++ N Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN-------DTGK-YILTIE--N 20851 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 VG ++S S +KV L P+ + + + ++TL W P GGSPI+ Y ++ Sbjct: 20852 GVGEPKSSTVS--VKV---LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE 20906 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 KR+ + W V+ S + +D L+E + + F++ A N GIGEP + +E K Sbjct: 20907 KRDATKRTWSVVSHKCSSTSFKLID-LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAE- 20964 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTA 868 P P DL+ + TS+++ W P + G S ++ Y V+ + + W + T Sbjct: 20965 ---VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 21021 Query: 869 NRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG---- 924 ++VS L++ FRV A N G+ P T P+ V+ T E+ D G Sbjct: 21022 E--IEVSQLKEQSVLEFRVFAKNEKGLSDPV-TIGPITVKELIITPEVDLS-DIPGAQVT 21077 Query: 925 -----NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGT 979 N++L + S +W K + + E + + L +KN KE G Sbjct: 21078 VRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGK 21136 Query: 980 YSV 982 Y+V Sbjct: 21137 YTV 21139 Score = 194 bits (493), Expect = 5e-49 Identities = 199/802 (24%), Positives = 323/802 (40%), Gaps = 126/802 (15%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P R P +W + D ++++ + SL ++++ D G YTL + + Sbjct: 16465 LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSS 16522 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G SAF+ VR D P P++L+ + +D V +TW+PP S + Y V++ Sbjct: 16523 GTK--SAFVTVRVLD-----TPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16575 Query: 422 CEVGTNNWVQCNDAPVKIC---KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478 E ++ A V C + + L EG SY FRV A N GI P++ +D + Sbjct: 16576 REATRKSYA----AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV- 16630 Query: 479 DPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRG 538 A+VP PP + +++RN V LSW P G Sbjct: 16631 -----------------------------AEVPQPPGKITVDDVTRNSVSLSWTKPEHDG 16661 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 ++ Y +E S W V+S + + +L +G+ Y+FRV++ N G S+P Sbjct: 16662 GSKIIQYIVEMQAKHSEKWSEC---ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16718 Query: 598 EITSPIQAQDVTVVPS-----APGRVLASRNTKTSVVVQWDRPKHE----------EDLL 642 + PI A+D+ + P + V ++ K V + RPK + Sbjct: 16719 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPIS-GRPKPTITWTKDGLPLKQTT 16777 Query: 643 GYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVI 702 V + T L HK G QY + N VG S E Sbjct: 16778 RINVTDSLDLTTLSIKETHK------------DDGGQY--GITVANVVGQKTASIEI--- 16820 Query: 703 KVQAALTVPSHPYG-ITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 L P P G + + S+TL W P ++GG I Y + KR+ W V+ Sbjct: 16821 ---VTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 16877 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAG--IGEPSDPSEHFKCEAWTMPEPGPAYDL 819 ++ ++ T L V L G+ Y+F+I A N G SDP + EPGP Sbjct: 16878 ATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI----VAQYPYKEPGPPGTP 16932 Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 + S+V+ W PV +G SPV GY ++ +E ++ W VN+T + K +L++ Sbjct: 16933 FATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEE 16992 Query: 880 GKTYVFRVRAVNANGVGK---------------PSDTSEPVLVEARPGTKEISAGVDEQG 924 G Y FRV A N GVGK P T EP++V+ T + + V + G Sbjct: 16993 GIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGG 17052 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 ++ G+ E D W K+ + +F + + + + + K G S Sbjct: 17053 SMITGY-IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17111 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAE-HLSP 1043 T +++ +E++ P I + + I F L+A+ H P Sbjct: 17112 DSTGPITA---------------KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKP 17156 Query: 1044 DASYRFIINDREVSDSEIHRIK 1065 + ++ D+E+ +S IK Sbjct: 17157 LPTIEWLRGDKEIEESARCEIK 17178 Score = 193 bits (490), Expect = 1e-48 Identities = 206/864 (23%), Positives = 336/864 (38%), Gaps = 147/864 (17%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 +K+ + G P PV+ W KDG + E + I S L + DT Y Sbjct: 19310 LKINADIAGRPLPVISWAKDG---IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19366 Query: 231 ATNAHG--QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF 288 N G V+ N V+ ++P G P G LE G+T Sbjct: 19367 LKNVAGTRSVAVNCKVL-------DKP----GPPAGP---------------LEINGLTA 19400 Query: 289 RREGETVTLKCTMLVTPDLKRVQPRAEWYRD-DVLLKESK------WTKMFFGEGQ-ASL 340 KC+ L +P+ + D D + E + WT + GE Q S Sbjct: 19401 E--------KCS------LSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSC 19445 Query: 341 SFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVI 400 + L K +E ++ + V++ GV + + ++ DP +P P L+ ++ + Sbjct: 19446 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSP--PTSLEITSVTKESMT 19503 Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + W P + S + GY ++R E + WV+ N PV + TGL EG Y +RV A Sbjct: 19504 LCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAE 19563 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 N+AG+S PS S + A DP+ L P PP+ Sbjct: 19564 NAAGLSLPSETSPLIRAEDPVFL---------------------------PSPPSKPKIV 19596 Query: 521 EISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGK 579 + + + ++W P G P+ Y +E W+ + ++R Y + L G Sbjct: 19597 DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK--TSIQSLRGTEYTISGLTTGA 19654 Query: 580 SYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV---------- 629 YVFRV S N+ G S+PS+ + P A++ P + S KT +V Sbjct: 19655 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFD---IDSEMRKTLIVKAGASFTMTV 19711 Query: 630 ---------VQWDRPKHEEDL-LGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGE 678 V W +P + DL YVD + T+L E N G + + + Sbjct: 19712 PFRGRPVPNVLWSKP--DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19769 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSG 738 VK L P P IT+ + S L W VP+ G Sbjct: 19770 SLTLVVK---------------------VLDTPGPPTNITVQDVTKESAVLSWDVPENDG 19808 Query: 739 GSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 G+P+ Y+++KRE K W V ++ ++ + V L EG++Y F+++ N G+G P++ Sbjct: 19809 GAPVKNYHIEKREASKKAWVSVTNNCNRLS-YKVTNLQEGAIYYFRVSGENEFGVGIPAE 19867 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 E K +P P L + S+ + W P + G S + Y V+ E+ Sbjct: 19868 TKEGVK----ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKN 19923 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 W V + + VS L++ Y FRV A N G+ P + PVL++ + EI Sbjct: 19924 W--VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDM 19981 Query: 919 GVDEQGNIYLGFDCQEMTD-------ASQFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 +Y+ D + T + + RF E ++ + LK Sbjct: 19982 KNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKE 20041 Query: 972 PDKEDLGTYSVSVSDTDGVSSSFV 995 D G Y ++ +++ G + +F+ Sbjct: 20042 SVTADAGRYEITAANSSGTTKAFI 20065 Score = 192 bits (489), Expect = 2e-48 Identities = 159/642 (24%), Positives = 274/642 (42%), Gaps = 79/642 (12%) Query: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438 +T P P L ++D V +TW P S ++ Y V+ E G NWV+C A K Sbjct: 19874 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAK 19931 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIA 498 + V+GL E Y FRV A N AG+S P + V + L+ + + Sbjct: 19932 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 19991 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVL--SWEPPTPRGKDPLMYFIEKSVVGSGSW 556 +L+ D + G P + +SR+ V L + T + L +++SV Sbjct: 19992 RAGSNLKVDIPISGKP--LPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGR 20049 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG 616 + A + + K+++ V+ L P T P+ D+T Sbjct: 20050 YEITAANSSGTT----------KAFINIVV------LDRPGPPTGPVVISDIT------- 20086 Query: 617 RVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGL 674 + SV ++W+ PK++ + Y + T +W + + V L Sbjct: 20087 --------EESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS-ATVARTMMKVMKL 20137 Query: 675 TTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVP 734 TTGE+Y FR+KA N G+S++ +S + V+ T P P + N S+T+GW P Sbjct: 20138 TTGEEYQFRIKAENRFGISDHI-DSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20196 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 +GGS ++GY+L+ ++ + W + N + T V ++ G +YEF++ A N AG+G Sbjct: 20197 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20256 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PS PSE + P ++ ++ S+ + W+ P + G S ++GY V+ R+ Sbjct: 20257 KPSHPSE----PVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL 20312 Query: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPV-------- 905 G W + T +S L Q Y FRV A NA G + PS+ P+ Sbjct: 20313 PDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGG 20372 Query: 906 -----------LVEARPGTK-EISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDD 953 +V+ R GT ++ AG+ + A W K +E+ + Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGK-------------PAPTIEWYKDDKELQTN 20419 Query: 954 ERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 +E D + + +K+ D+ + G Y + + + G +S+ + Sbjct: 20420 ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATI 20461 Score = 191 bits (485), Expect = 4e-48 Identities = 214/857 (24%), Positives = 337/857 (39%), Gaps = 113/857 (13%) Query: 177 VQGFPTPVVQWYKDGSLI---CQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATN 233 V G P P ++W K+ ++I A + K + + L I +A +D TY+ A+N Sbjct: 8925 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASN 8984 Query: 234 AHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGE 293 G V N V E + P L ++ D++ E +T+ + Sbjct: 8985 RLGSVFRNVHV---------EVYDRPSPPRNLAVT--------DIK-AESCYLTWDAPLD 9026 Query: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLY 353 + T V + +AEW E ++ L + + + Sbjct: 9027 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRY------------GIWKLIPNGQYEF 9074 Query: 354 TLRIVSRGGVSDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 +R V++ G+SD V DP + G PG P L + ++V+W PP S Sbjct: 9075 RVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---RTKGSMLVSWTPPLDNGGS 9131 Query: 413 PVMGYFVDRCEVGTNNWVQCNDAPV-----KICKYPVTGLFEGRSYIFRVRAVNSAGISR 467 P+ GY++++ E G+ W + + AP+ K ++ V L EG Y FR A+N+AGI Sbjct: 9132 PITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGP 9191 Query: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527 PS SD A DP+ PGPP+ + +++ + Sbjct: 9192 PSEPSDPEVAGDPIF---------------------------PPGPPSCPEVKDKTKSSI 9224 Query: 528 VLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA-QTAVRSPRYAVFDLMEGKSYVFRV 585 L W+PP G P+ Y +E G+ W+RVN + + V +L E + Y FRV Sbjct: 9225 SLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRV 9284 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA---------SRNTKTSVVVQWDRPK 636 + N G SEPS+ T I A D+ P + A S+ +V+ PK Sbjct: 9285 KAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPK 9344 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV-----HGLTTGEQYIFRVKAVNAVG 691 + G G + N V+ TG+ + + A N G Sbjct: 9345 SSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK---YSITAKNKAG 9401 Query: 692 MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751 Q++ +V+ + VP P + + + S L WK+P GG I GY ++KR Sbjct: 9402 -----QKTANCRVKV-MDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT 9455 Query: 752 VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811 + K W +VN T + D L+E Y F++ A N GIG P + + P Sbjct: 9456 IDGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYP 9514 Query: 812 EPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED-----AGEWITVNQTT 866 P P L + ++ + WK P G SPV+ Y V+ D W N+ Sbjct: 9515 -PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573 Query: 867 TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEIS----AGVDE 922 V DL +G Y FRV+AVNA GV KPS T P + I V+E Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9633 Query: 923 QGNIYLGFDCQEMTDASQFTWCK-------SYEEISDDERFKIETVGDHSKLYLKNPDKE 975 N+ + + + + TW K + E + D V D L + + Sbjct: 9634 GTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9692 Query: 976 DLGTYSVSVSDTDGVSS 992 D G Y+++ + G +S Sbjct: 9693 DTGLYTITAVNNLGTAS 9709 Score = 188 bits (478), Expect = 3e-47 Identities = 179/740 (24%), Positives = 304/740 (41%), Gaps = 121/740 (16%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 VQW ++ ++ Q K+++ S +H L+I D Y +A + + A Sbjct: 6445 VQWLRNNMVVVQG---DKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAA 6501 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 + D++ + + +G PL+ ++PY + Sbjct: 6502 APKIKTADQD----LVVDVGKPLTMVVPYDAYP--------------------------- 6530 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG-QASLSFSHLHKDDEGLYTLRIVSRGGV 363 + AEW++++ L TK Q S K D+G Y + + ++ G Sbjct: 6531 ------KAEAEWFKENEPLS----TKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6580 Query: 364 SDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 ++ L V D PG +L+ + V + W+ P T S ++GY V+R + Sbjct: 6581 AEGFINLKVIDV-------PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6633 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGR-SYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + WV D + C++ VTGL +G Y+FRV A N G P + V A D Sbjct: 6634 IKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYD 6692 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT-PRGKDP 541 VPGPP V ++++R V L+WEPP G + Sbjct: 6693 ---------------------------VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6725 Query: 542 LMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITS 601 Y IE S W A V D++EG+ Y FRV + NR G+ +PS T Sbjct: 6726 TNYVIELRDKTSIRWDTAMTVRA-EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6784 Query: 602 PIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPC 659 ++ D PS P + +S T++SV ++W+ P + +LGY ++ C G + W C Sbjct: 6785 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRC 6844 Query: 660 NHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ-----ESDVIKVQAALTVPSHP 714 N K + + V GL G +Y++RV A N G+S+ S+ +D V+ + + + Sbjct: 6845 NMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFK 6904 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNS-SPSKPTILTVD 773 G+ ++ + ++ VP P + + + + ++ + S +++ Sbjct: 6905 DGLEVIVPNPITIL----VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPS 6960 Query: 774 GLTEGSLYEFKI--------AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVR 825 ++ +Y K+ +++ I PS P E L F ++ Sbjct: 6961 ERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKE-----------------LKFGDIT 7003 Query: 826 DTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W+ P G SP++GY V+ RE W V T + V DL QGK Y+F Sbjct: 7004 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEF-TVPDLVQGKEYLF 7062 Query: 886 RVRAVNANGVGKPSDTSEPV 905 +V A N G G+P+ EPV Sbjct: 7063 KVCARNKCGPGEPAYVDEPV 7082 Score = 188 bits (477), Expect = 4e-47 Identities = 145/509 (28%), Positives = 233/509 (45%), Gaps = 82/509 (16%) Query: 371 FVRDADPLVTG----APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGT 426 FV ++ LV P P DL+ + ++ V +TW PP S ++ Y ++ +GT Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10263 Query: 427 NNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG------ISRPSRVSDAVAA--- 477 + + + + KY V GL EG +Y +RV AVN G ++P D +A Sbjct: 10264 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10323 Query: 478 ----LDPLDLRRLQAVHLEG-------------EKEIAIYQDDL---------------- 504 D L +R +A L G + E + +DD Sbjct: 10324 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10383 Query: 505 --------------------EGDAQV-----PGPPTG-VHASEISRNYVVLSWEPPTPRG 538 +G QV PGPP G V E++++Y+V+SW+PP G Sbjct: 10384 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10443 Query: 539 KDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPS 597 + Y IEK VG W V + +A + + V L+EGK Y+FR+ + N +G+S+P Sbjct: 10444 GSKITNYIIEKKEVGKDVWMPVTSASAKTTCK--VSKLLEGKDYIFRIHAENLYGISDPL 10501 Query: 598 EITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL 655 ++ ++A+D VP AP + + + TK S +V W++P H+ + + Y ++ + Sbjct: 10502 -VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKR 10559 Query: 656 WEPCNHKPIG-YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHP 714 W PI Y +F V L G QY FRV A N +G+ + S S + + + PS P Sbjct: 10560 WARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPP 10619 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTV 772 ++ +S+ L W+ P+ GGS ILGY ++ ++V + W N +P T V Sbjct: 10620 VNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKV 10679 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSE 801 GL +G Y+F++ AVN AG +P+ E Sbjct: 10680 TGLRDGQTYKFRVLAVNAAGESDPAHVPE 10708 Score = 187 bits (476), Expect = 5e-47 Identities = 190/783 (24%), Positives = 312/783 (39%), Gaps = 105/783 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + + V R +K+ +G P V W KDG + E + + S+ V + Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTL---KETTRVNVSSSKTVTS 18954 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I A +D TY +N+ G ++ ++V G P R + S P Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPP 19014 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + + + ++E + T W + Sbjct: 19015 EYDGGCQISNY-IVEKKETTSTT-------------------------------WHIVSQ 19042 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHD 393 + S+ L E + + +R G S +S V P PG P + Sbjct: 19043 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPF--SPPGPPGTPKVVH 19100 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 A + ++VTW+ P S V+GY ++ E + W + N + + V+GL EG Y Sbjct: 19101 ATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMY 19160 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 +RV A N AGI + S+ + V A DP D P Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCD------------------------------P 19190 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + I+R V L W P G + Y +E+ + G W + N T ++ + V Sbjct: 19191 PGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCN-YTNIQETYFEV 19249 Query: 573 FDLMEGKSYVFRVLSAN-RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 +L E + Y FRV + N +SEPSE T PI +D P RV+ + +VV+ Sbjct: 19250 TELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKD----DVEPPRVMMDVKFRDVIVVK 19305 Query: 632 -WDRPKHEEDLLGY---YVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------Q 679 + K D+ G + G + E + I + H L T + Q Sbjct: 19306 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN---HTLLTVKDCIRRDTGQ 19362 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y+ +K N G + V+ P G+T C +L W P+ GG Sbjct: 19363 YVLTLK--NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKC-----SLSWGRPQEDGG 19415 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + I Y ++KRE H W + + T V L +G+ Y F++ VN G+GEP + Sbjct: 19416 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19474 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 + +T+P P + ++T V S+ + W P G S +SGY ++ RE+++ W Sbjct: 19475 VAIKALDPFTVPSPPTSLEIT--SVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRW 19532 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS------EPVLVEARPGT 913 + VN+ + +K + L++G Y +RV A NA G+ PS+TS +PV + + P Sbjct: 19533 VRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSK 19592 Query: 914 KEI 916 +I Sbjct: 19593 PKI 19595 Score = 187 bits (475), Expect = 6e-47 Identities = 180/671 (26%), Positives = 294/671 (43%), Gaps = 73/671 (10%) Query: 349 DEGL-YTLR-----IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIV 401 DEGL Y + IV G S S RD DP PG P + R+ V + Sbjct: 18073 DEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP-----PGRPEAIVI---TRNNVTL 18124 Query: 402 TWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVN 461 WK P S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N Sbjct: 18125 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18184 Query: 462 SAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDD---LEGDAQVPGPPTGV 517 +AG S PS S A+ A D +D ++ + + I ++ + LE D + P V Sbjct: 18185 AAGNFSEPSDSSGAITARDEIDAPNA-SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV 18243 Query: 518 HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLM- 576 + + GK+ +E++ R+ ++ ++ V D + Sbjct: 18244 WSKD----------------GKE-----LEETAA------RMEIKSTIQKTTLVVKDCIR 18276 Query: 577 -EGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRP 635 +G Y+ ++ + G ++ IT ++ D P P +V T + W+ P Sbjct: 18277 TDGGQYILKLSNV---GGTKSIPIT--VKVLDRPGPPEGPLKVTGV--TAEKCYLAWNPP 18329 Query: 636 KHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMS 693 + ++ Y ++ W + + N + V L G +YIFRV AVN G+ Sbjct: 18330 LQDGGANISHYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIG 18388 Query: 694 ENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 E ES + P P + SM + W P GG+ I GY L+KR+ Sbjct: 18389 E-PLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKE 18447 Query: 754 HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPE 812 W + N L V GLTEG YEF++AA N AG+GEPS+PS ++ C+A + Sbjct: 18448 GVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA--LYP 18505 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTT-TANRY 871 PGP + + +S+ + W P+Y G +PV GY V+ +E A EW T T + Sbjct: 18506 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18565 Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLG-- 929 V+ L++ Y FR+ A+N+ GVG+P+ V+ + R EI D + + L Sbjct: 18566 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18625 Query: 930 -----FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 F + + W K+ ++D R +IE + L + N + D G Y++++ Sbjct: 18626 ATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 18683 Query: 985 SDTDGVSSSFV 995 + G ++FV Sbjct: 18684 ENNSGSKTAFV 18694 Score = 187 bits (474), Expect = 8e-47 Identities = 169/652 (25%), Positives = 277/652 (42%), Gaps = 58/652 (8%) Query: 357 IVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415 IV G S S RD DP PG P + R+ V + WK P S + Sbjct: 15923 IVGIGKPSKVSECYVARDPCDP-----PGRP---EAIIVTRNSVTLQWKKPTYDGGSKIT 15974 Query: 416 GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI-SRPSRVSDA 474 GY V++ E+ W++ + + + VTGL E Y FRV A N+AG+ S PS + A Sbjct: 15975 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16034 Query: 475 VAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPP 534 + A D +D R+ + + + + DA + G P + W Sbjct: 16035 ITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-----------IQWI-- 16081 Query: 535 TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLS 594 +G L + + ++ + AVR ++ +Y+ + + ++ Sbjct: 16082 --KGDQELSNTARLEIKSTDFATSLSVKDAVR---------VDSGNYILKAKN-----VA 16125 Query: 595 EPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAG 652 +T ++ D P P V+ S T + W P + D++ Y V+ Sbjct: 16126 GERSVTVNVKVLDRPGPPEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETS 16183 Query: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712 +W + + V L G +Y FR+ AVN G+ E ES+ + + VP Sbjct: 16184 RLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE-PLESEPVVAKNPFVVPD 16241 Query: 713 HPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 P + SM + W+ P GGS ILGY L+KR+ W + L V Sbjct: 16242 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16301 Query: 773 DGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVM 831 GL E YEF+++A N AG+ EPS PS + K C+ + +PGP + ++ +S+ + Sbjct: 16302 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDITRSSVFL 16359 Query: 832 LWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKTYVFRVRAV 890 W P+Y G + GY V+ + GEW T N+ ++V L + Y FR+ A+ Sbjct: 16360 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 16419 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQG--NIYLG-----FDCQEMTDASQFTW 943 N GVG+ +D P++VE + +I ++ + NI G F + + W Sbjct: 16420 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 16479 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 K EI D I+ + L L N ++ D G Y++++ ++ G S+FV Sbjct: 16480 GKVDGEIRD--AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 16529 Score = 186 bits (473), Expect = 1e-46 Identities = 191/764 (25%), Positives = 296/764 (38%), Gaps = 106/764 (13%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++ S++V +K+ + G P P + W KDG + Q + + + + T Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT---RINVTDSLDLTT 16789 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L I DD Y N GQ + + +V + P P Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIVT----------------LDKPDPPKGPV 16833 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 DV E++TL + ++ RD + W + Sbjct: 16834 KFDDV------------SAESITLSWNPPLYTGGCQITNYIVQKRDTT---TTVWDVVSA 16878 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT-------GAPGAP 386 + +L + L E + + +R G S F ++DP+V G PG P Sbjct: 16879 TVARTTLKVTKLKTGTEYQFRIFAENRYGQS------FALESDPIVAQYPYKEPGPPGTP 16932 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 ++D +++ W P SPV+GY ++R E + W + N + ++ Sbjct: 16933 F---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN 16989 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L EG Y FRV A N G+ + S+ S+ A DP D Sbjct: 16990 LEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD------------------------ 17025 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAV 565 PG P + + RN + L W P G + Y +EK + G W + + T V Sbjct: 17026 ---PPGTPEPI---MVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF-TNV 17078 Query: 566 RSPRYAVFDLMEGKSYVFRVLSANRHG-LSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 ++ V L E + Y FRV++ N G +S+PS+ T PI A+D +P R+ Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP----RISMDPKF 17134 Query: 625 KTSVVVQ-WDRPKHEEDLLGYYVDCC--VAGTNLWEP---CNHKPIGYNRFVVHG---LT 675 + ++VV + + E D+ G + + G E C K + ++ Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17194 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G QYI R A N G V+ P G+T C +L W P Sbjct: 17195 DGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC-----SLTWSPPL 17247 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I Y ++KRE W V +S L V L EG+ Y F+I AVN G+GE Sbjct: 17248 QDGGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17306 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 P + + + + PGP L + S+ + W P G S + GY V+ R+ Sbjct: 17307 PLESAPVLMKNPFVL--PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRS 17364 Query: 856 AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPS 899 WI N+ + L+V+ L + Y FRV A NA GVG+PS Sbjct: 17365 GIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17408 Score = 186 bits (471), Expect = 2e-46 Identities = 169/660 (25%), Positives = 282/660 (42%), Gaps = 64/660 (9%) Query: 352 LYTLRIVSRGGVSDHSAFLFVRD-ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 +Y IV G S +S RD DP PG P + R+ + + W P Sbjct: 17000 VYAENIVGVGKASKNSECYVARDPCDP-----PGTPEPIM---VKRNEITLQWTKPVYDG 17051 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPS 469 S + GY V++ ++ W++ + V ++ V+GL E + Y FRV A N+AG IS+PS Sbjct: 17052 GSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPS 17111 Query: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529 + + A D ++L R+ + + + +A V G P + Sbjct: 17112 DSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT-----------I 17160 Query: 530 SWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W RG + + + + + A+R ++G Y+ R + Sbjct: 17161 EWL----RGDKEIEESARCEIKNTDFKALLIVKDAIR---------IDGGQYILRASN-- 17205 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 ++ ++ D P P +V + K S+ W P + D+ Y V+ Sbjct: 17206 ---VAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT--WSPPLQDGGSDISHYVVE 17260 Query: 648 CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707 W + + N V L G +Y+FR+ AVN G+ E + + V+ ++ Sbjct: 17261 KRETSRLAWTVVASEVVT-NSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL-MKNP 17318 Query: 708 LTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP 767 +P P + + N SMT+ W P GGS I+GY ++KR+ W + N Sbjct: 17319 FVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD 17378 Query: 768 TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRD 826 L V GLTE YEF+++A N AG+GEPS + ++K C+ + +PGP + + Sbjct: 17379 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD--PVFKPGPPTNAHIVDTTK 17436 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW-ITVNQTTTANRYLKVSDLQQGKTYVF 885 S+ + W P+Y G S + GY V+ + D EW I QT ++S L + + Y Sbjct: 17437 NSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKI 17496 Query: 886 RVRAVNANGVG---------KPSDTSE-PVLVEARPGTKEISAGVDEQGNIYLGFDCQEM 935 RV A+N G+G KP D E P L K I I++ F + Sbjct: 17497 RVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPF---KG 17553 Query: 936 TDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + TW + E +D + +IE ++++L + N D+ D G Y + + ++ G S+FV Sbjct: 17554 RPTPEITWSREEGEFTD--KVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17611 Score = 186 bits (471), Expect = 2e-46 Identities = 189/804 (23%), Positives = 332/804 (41%), Gaps = 87/804 (10%) Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP-IGLPLSSMIPYTHFDVQFLEKFG 285 + A NA G +S + VV G S G P I LPL YT Sbjct: 20343 FRVFARNAVGSISNPSEVV-----GPITCIDSYGGPVIDLPLE----YTE---------- 20383 Query: 286 VTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHL 345 V R G +V L+ + P P EWY+DD L+ + + AS+ Sbjct: 20384 VVKYRAGTSVKLRAGISGKP-----APTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438 Query: 346 HKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + + G Y L++ R + SA + V+ D G PG P++ + A + + + W+P Sbjct: 20439 DRLNSGCYELKL--RNAMGSASATIRVQILDK--PGPPGGPIEFKTVTAEK--ITLLWRP 20492 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P + + Y V++ E W ++ ++ C T + +G YIFRVRAVN GI Sbjct: 20493 PADDGGAKITHYIVEKRETSRVVWSMVSEH-LEECIITTTKIIKGNEYIFRVRAVNKYGI 20551 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P SD+V A + PGPP ++I++N Sbjct: 20552 GEPLE-SDSVVAKNAF---------------------------VTPGPPGIPEVTKITKN 20583 Query: 526 YVVLSWEPP-TPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 + + W P G D YF+EK S W +V +T +R R V L E Y +R Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET-IRDTRQKVTGLTENSDYQYR 20642 Query: 585 VLSANRHG---LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--E 639 V + N G SEPSE +A D P P ++ + +TK+S+ + W +P ++ Sbjct: 20643 VCAVNAAGQGPFSEPSEF---YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGS 20699 Query: 640 DLLGYYVDCCVAGTNLWEPCNHK-PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 + GY V+ W + K + +VV L G Y FRV AVN G E + Sbjct: 20700 AVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM 20759 Query: 699 SDVIKVQAALTVPSHPYGITL----LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHH 754 ++ ++ + L P + L + G + + +P P + + D++ + Sbjct: 20760 NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV--LIPFKGRPPPTVTWRKDEKNLGS 20817 Query: 755 KNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG 814 + + ++ S ++LT+ +T ++ + N G+GEP + K + P Sbjct: 20818 DARYSIENTDSS-SLLTIPQVTRNDTGKYILTIEN--GVGEPKSSTVSVK----VLDTPA 20870 Query: 815 PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKV 874 L V ++ +LW P+ G SP+ Y ++ R+ W V+ ++ + K+ Sbjct: 20871 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSF-KL 20929 Query: 875 SDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPG-TKEISAGVDEQGNIYLGFDCQ 933 DL + + FRV A N G+G+P +T+EPV P +++S + ++ L + Sbjct: 20930 IDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKP 20989 Query: 934 EMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993 + S T + ++ + + ++ + ++ + + V + G+S Sbjct: 20990 DFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 21049 Query: 994 FVLDPEELERLMALSNEIKNPTIP 1017 + P ++ L+ ++ E+ IP Sbjct: 21050 VTIGPITVKELI-ITPEVDLSDIP 21072 Score = 185 bits (470), Expect = 2e-46 Identities = 164/638 (25%), Positives = 263/638 (41%), Gaps = 91/638 (14%) Query: 381 GAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC 440 G PG P + + ++ V+WK P S + GY V+R E + WV+ PV Sbjct: 14073 GPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDL 14132 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 + VTGL EG +Y FRV A N AGI PS SD+V D Sbjct: 14133 RCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA-------------------- 14172 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 A PGPP+ H ++ ++ L+W +P G + Y +E VG +W + Sbjct: 14173 -------AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14225 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGR 617 TA+R ++ V DL + Y FR+ + N G+ EP+ I DV +V AP Sbjct: 14226 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIP------DVEIVEREMAPDF 14279 Query: 618 VLASRNTKTSVVVQW----------DRPKHE----EDLLGYYVDCCVAGTNLWE-----P 658 L + +T VV RP E +D + + T + Sbjct: 14280 ELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPE 14339 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT 718 CN G + + V+ ++ G N + +D+ K Sbjct: 14340 CNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK--------------- 14384 Query: 719 LLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 S+TL W +P GGS I Y ++KRE K++ + K T V GL+EG Sbjct: 14385 ------DSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLSEG 14437 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 Y F++ A N GIGEP++ +E K P P L ++ +++ + W P + Sbjct: 14438 CEYFFRVMAENEYGIGEPTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKH 14493 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G S ++GY ++ + + + +W + TT V +L +G+ Y F+V AVN+ G P Sbjct: 14494 DGGSKITGYVIEAQRKGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14551 Query: 899 SDTSEPVLVEARPGTKEISA-GVDEQGNIYLGFDCQEMT------DASQFTWCKSYEEIS 951 + S PV+V+ + E+ G+ ++ I D ++ TW K + + Sbjct: 14552 RE-SRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK 14610 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 +R ET + L + + D G Y ++ + G Sbjct: 14611 QTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG 14648 Score = 185 bits (470), Expect = 2e-46 Identities = 164/623 (26%), Positives = 257/623 (41%), Gaps = 58/623 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P + D R+ V ++W+ P S ++GY V+ G++ W C A VK+ + Sbjct: 15552 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEA 15609 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 +TGL +G Y FRV A N GIS P ++S V A D L A L + + Sbjct: 15610 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---LVIPPAFKLLFNTFTVLAGE 15666 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQ 562 DL+ D G PT ++W K V RVNA+ Sbjct: 15667 DLKVDVPFIGRPTPA-----------VTWH---------------KDNVPLKQTTRVNAE 15700 Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PSAP-GRVL 619 + + + D + V N G I+ +V V+ P P G V Sbjct: 15701 STENNSLLTIKDACREDVGHYVVKLTNSAG--------EAIETLNVIVLDKPGPPTGPVK 15752 Query: 620 ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTG 677 T S+ + W PK++ + Y V+ T W+ + + L TG Sbjct: 15753 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-ATVARTTIKACRLKTG 15811 Query: 678 EQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFS 737 +Y FR+ A N G S + Q VP P + SM + W P Sbjct: 15812 CEYQFRIAAENRYGKSTYLNSEPTV-AQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISD 15870 Query: 738 GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPS 797 GGS ++GY+L+++E + W ++N +P T GL EG YEF+++A N+ GIG+PS Sbjct: 15871 GGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPS 15930 Query: 798 DPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAG 857 SE + P P + V S+ + WK P Y G S ++GY V+ +E G Sbjct: 15931 KVSECYVARDPCDPPGRPEAII----VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 15986 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLVEARPGTKEI 916 W+ + T + + +V+ L + Y FRV A NA GV +PS+++ + I Sbjct: 15987 RWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRI 16046 Query: 917 SAGVDEQGNIYLGFDCQEMTDASQF-------TWCKSYEEISDDERFKIETVGDHSKLYL 969 S + I + DA + W K +E+S+ R +I++ + L + Sbjct: 16047 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106 Query: 970 KNPDKEDLGTYSVSVSDTDGVSS 992 K+ + D G Y + + G S Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERS 16129 Score = 185 bits (469), Expect = 3e-46 Identities = 198/834 (23%), Positives = 347/834 (41%), Gaps = 94/834 (11%) Query: 170 SVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSA 229 +++L ++G P P V W K+ P K RI+ LEI A +D YS Sbjct: 10738 TLRLSAIIKGVPFPKVTWKKE-----DRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10792 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 N G + + V+V ++P G P L +S + R Sbjct: 10793 TVENPAGSKTVSVKVLVL-----DKP----GPPRDLEVSEI------------------R 10825 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 ++ +T K + D V R DV ++W+ + + S HL++ + Sbjct: 10826 KDSCYLTWKEPL---DDGGSVITNYVVERRDVA--SAQWSPLSATSKKKSHFAKHLNEGN 10880 Query: 350 EGLYTLRIVSRGGVSDHSAFLF----VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKP 405 + L+ + ++ G F+ ++ DPL PG P DL D ++ V + W Sbjct: 10881 QYLFRVAAENQYG---RGPFVETPKPIKALDPL--HPPGPPKDLHHVDVDKTEVSLVWNK 10935 Query: 406 PNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGI 465 P+ SP+ GY V+ E GT +W++ C VTGL +G++Y FRV+A N G+ Sbjct: 10936 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV--VTGLQQGKTYRFRVKAENIVGL 10993 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 P P++ + + V E ++ + +EG G T V I R Sbjct: 10994 GLPDTTI-------PIECQE-KLVPPSVELDVKL----IEGLVVKAG--TTVRFPAIIRG 11039 Query: 526 YVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRV 585 P P K + + S + + + +T S + + + + +++ Sbjct: 11040 V-------PVPTAK----WTTDGSEIKTD--EHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086 Query: 586 LSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643 +N G + + DV P+ P +L T + + W PK + ++ Sbjct: 11087 TVSNAAG---SKTVAVHLTVLDVPGPPTGPINILDV--TPEHMTISWQPPKDDGGSPVIN 11141 Query: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 Y V+ + W + + H L G +Y+FRV+A N +G+ + + Sbjct: 11142 YIVEKQDTRKDTWGVVSSGSSKTKLKIPH-LQKGCEYVFRVRAENKIGVGPPLDSTPTV- 11199 Query: 704 VQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + + PS P + + ++ T+ W +PK GGSPI GYY+++REV K W VN + Sbjct: 11200 AKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVNKT 11258 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 P V GL EG+ YEF++ A NLAG+ +PS S+ K P PGP + + Sbjct: 11259 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKP-PGPPINPKLKD 11317 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANR-YLKVSDLQQGKT 882 + ++W P+ G SP+ GY V+ ++ +W +N+ + +V L +G Sbjct: 11318 KSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNE 11377 Query: 883 YVFRVRAVNANGVGKPSDTSEPVLVE--ARPGTKEISAGVDEQGNIYLGFDCQEMTDAS- 939 Y FR++A N G G+P + +E V+ + P E+ + + +G + + Sbjct: 11378 YRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKG 11437 Query: 940 ----QFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 TW K + + ++R + +L +K + D G Y +S ++ G Sbjct: 11438 RPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11491 Score = 185 bits (469), Expect = 3e-46 Identities = 204/870 (23%), Positives = 337/870 (38%), Gaps = 134/870 (15%) Query: 161 RSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 ++H V S++L QG PTP W K S + A+ I + TL + + Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHTTDSFSTLTVENCN 21922 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFR-------SVGLPIGLPLSSMIPY 273 +D Y+ N G S V V G P S L PL Sbjct: 21923 RNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGAR 21982 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 H V +EK + RR + ++ KCT + Sbjct: 21983 IHHYV--VEKREAS-RRSWQVISEKCTRQI------------------------------ 22009 Query: 334 GEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV-TGAPGAPMDLQCH 392 + L + + + V+ GV + +P+V T P P L Sbjct: 22010 ------FKVNDLAEGVPYYFRVSAVNEYGVGEPYEM-----PEPIVATEQPAPPRRLDVV 22058 Query: 393 DANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 D ++ ++ W P+ S + GY ++ + G++ WV+ K + V L E Sbjct: 22059 DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTFTVERLVEKTE 22116 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y FRV+A N AG S P +V +P +E ++ + L G Sbjct: 22117 YEFRVKAKNDAGYSEPREAFSSVIIKEP---------QIEPTADLTGITNQLI--TCKAG 22165 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P + R ++W+ R K+ RV+ T V Sbjct: 22166 SPFTIDVPISGRPAPKVTWKLEEMRLKET---------------DRVSITTTKDRTTLTV 22210 Query: 573 FDLMEGKSYVFRVLSANRHG----------LSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 D M G S + + N G + P +T PI+ V+ Sbjct: 22211 KDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSA------------ 22258 Query: 623 NTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680 S V+ W PK ++ Y V+ +GT W+ N + + V LT +Y Sbjct: 22259 ---ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEY 22314 Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 FRV + N G+S+ + + +I + PS P + + ++M++ W+ P GGS Sbjct: 22315 SFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGS 22373 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 I+GY+++K+E + W + N P V GL EG Y+F+ A+N AG+ + S+ S Sbjct: 22374 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 22433 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFR---EEDAG 857 + + PG +V +++ ++W AP Y G S V GY ++ + E G Sbjct: 22434 RPIMAQN-PVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 22489 Query: 858 EWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV-GKPSDTSEPVLV--EARPGTK 914 W+ N T ++ + V+ L +G TY FRV A NA GV K S+++ PV E P Sbjct: 22490 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 22549 Query: 915 EISAGV-DEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 E+ A + + I G D + DA+ + W K +E+ E+ ++ G + Sbjct: 22550 ELDARLHGDLVTIRAGSDL--VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT 22607 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFVL 996 +K D+ D G Y+++V + G + V+ Sbjct: 22608 AVIKFCDRSDSGKYTLTVKNASGTKAVSVM 22637 Score = 184 bits (466), Expect = 7e-46 Identities = 162/629 (25%), Positives = 274/629 (43%), Gaps = 63/629 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG +DL+ ++ + WK P++ S ++GY VD N W + + +Y Sbjct: 13387 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKS--LSLQY 13443 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVS----DAVAALDPLDLRRLQAVHLEGEKEIA 498 L EG+ Y FRV A N G PS ++ D V A D LDL+ L + Sbjct: 13444 SAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPD-LDLKGLPDL--------- 13493 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 Y + ++ P G A +S W+ +G+DPL + R Sbjct: 13494 CYLAKENSNFRLKIPIKGKPAPSVS-------WK----KGEDPL-----------ATDTR 13531 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V+ +++ + V+D + + + + N G E T I+ +P+ P + Sbjct: 13532 VSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG---TISIKVVGKPGIPTGP--I 13586 Query: 619 LASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTT 676 T ++ ++W PK + ++ Y ++ + N W C + F V L Sbjct: 13587 KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCA-SAVQKTTFRVTRLHE 13645 Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +Y FRV A N G+ E + S+ I + VP P +++ S++L W PK Sbjct: 13646 GMEYTFRVSAENKYGVGEGLK-SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKK 13704 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 +GGSPI GY+L+ +E + W N +P + V GLTEG YEF++ A+NLAG+G+P Sbjct: 13705 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13764 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S PSE + P + S+ ++W P Y G ++GY V+ R+ + Sbjct: 13765 SLPSE----PVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPS 13820 Query: 857 GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVN-ANGVGKPSDTSEPVLV--EARPGT 913 W+ N V+DL +G Y FR+RA N A + PS+++E ++ E T Sbjct: 13821 KSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPT 13880 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYEEISDDERFKIETVGDHSK 966 + + + I G D + S + +W K+ ++I + +I + S Sbjct: 13881 IVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 13939 Query: 967 LYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 L +K ++D G Y+++ ++ G V Sbjct: 13940 LTIKYATRKDAGEYTITATNPFGTKVEHV 13968 Score = 184 bits (466), Expect = 7e-46 Identities = 157/633 (24%), Positives = 259/633 (40%), Gaps = 56/633 (8%) Query: 283 KFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSF 342 K G+T + G+T+ L ++ L P++ W + ++ S T++ + L+ Sbjct: 13888 KDGLTIKA-GDTIVLNAISILGKPL----PKSSWSKAGKDIRPSDITQITSTPTSSMLTI 13942 Query: 343 SHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVT 402 + + D G YT+ + G V V PG P ++ + + + +T Sbjct: 13943 KYATRKDAGEYTITATNPFGTK-------VEHVKVTVLDVPGPPGPVEISNVSAEKATLT 13995 Query: 403 WKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNS 462 W PP SP+ Y +++ E W ++ ++ C++ T L +G YIFRV AVN Sbjct: 13996 WTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNH 14054 Query: 463 AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEI 522 G P + S+ V +D PGPP S + Sbjct: 14055 YGKGEPVQ-SEPVKMVDRFG---------------------------PPGPPEKPEVSNV 14086 Query: 523 SRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSY 581 ++N +SW+ P G + Y +E+ S W R +T V R V L EG +Y Sbjct: 14087 TKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTY 14145 Query: 582 VFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE-- 639 FRV + NR G+ PSE + + +D P P + TK S + W +P ++ Sbjct: 14146 EFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGL 14205 Query: 640 DLLGYYVDCCVAGTNLW-EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698 ++ GY V+ G W + + +FVV L T E+Y FR+ A+N G+ E + Sbjct: 14206 EITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14265 Query: 699 SDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWH 758 DV V+ + P L L ++ G P K ++ KN Sbjct: 14266 PDVEIVEREM-APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRA 14324 Query: 759 EVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818 + ++ S T+L + +F + N AG + + PGP + Sbjct: 14325 NIENTESF-TLLIIPECNRYDTGKFVMTIENPAG-------KKSGFVNVRVLDTPGPVLN 14376 Query: 819 LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQ 878 L ++ S+ + W P+ G S ++ Y V+ RE + T Y KV+ L Sbjct: 14377 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTY-KVTGLS 14435 Query: 879 QGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP 911 +G Y FRV A N G+G+P++T+EPV P Sbjct: 14436 EGCEYFFRVMAENEYGIGEPTETTEPVKASEAP 14468 Score = 184 bits (466), Expect = 7e-46 Identities = 233/952 (24%), Positives = 374/952 (39%), Gaps = 107/952 (11%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR---CEVGTNNWVQCNDAPVK 438 APG P + D R V + W P S V+GY ++R EVG W++CN V Sbjct: 22444 APGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22500 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQA-VHLEGEKE 496 + VT L EG +Y FRV A N+AG IS+ S + V D + + L G+ Sbjct: 22501 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22560 Query: 497 IAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK-DPLMYFIEKSVVGSGS 555 DL DA V G P EP K D + EK Sbjct: 22561 TIRAGSDLVLDAAVGGKP-----------------EPKIIWTKGDKELDLCEK------- 22596 Query: 556 WQRVNAQ-TAVRSPRYAVF-DLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS 613 V+ Q T R+ F D + Y V +A+ G S + + + P Sbjct: 22597 ---VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNAS--GTKAVSVMVKVLDS------PG 22645 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVV 671 G++ SR T+ + W P+ + ++ Y V+ W + + +VV Sbjct: 22646 PCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVV 22704 Query: 672 HGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGW 731 L +YIFRV+AVN G ES+ I + + T+PS P + + + W Sbjct: 22705 TRLIKNNEYIFRVRAVNKYGPGV-PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQW 22763 Query: 732 KVPKFSGGSPILGYYLDKREVHHKNWHEVNSS-PSKPTILTVDGLTEGSLYEFKIAAVNL 790 P+ GG+ I Y +DKRE W VN T L V L EG Y+F++ AVN Sbjct: 22764 TKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNA 22823 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 AG EPS+ S C + PGP + S+ + W P+Y G + + GY ++ Sbjct: 22824 AGNSEPSEASNFISCREPSYT-PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 22882 Query: 851 FREEDAGEWITVN-QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT---SEPVL 906 +E+D +W V+ T N V DL+ G+ Y FRV AVN G+ + S++ EPV Sbjct: 22883 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 22942 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETV 961 P E++ + + I G + M S TW K +++ R I+T Sbjct: 22943 RIEIPDL-ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTT 22999 Query: 962 GDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSE 1021 +S L + ++ D G Y++ + G S+ VL ++ + P S Sbjct: 23000 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL------------VKVYDTPGPCPSV 23047 Query: 1022 LAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRI--KCDKA----TGIIEM 1075 E+ W +I+ RE + + KC K +G++E Sbjct: 23048 KVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEG 23107 Query: 1076 VMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEY 1135 M F + E Y + G+ S VL+ + L A+ + + + Sbjct: 23108 TMYYFRVLPENIYGI----GEPCETSDAVLVSE---VPLVPAKLEVVDVTKS-----TVT 23155 Query: 1136 LHWD-VTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKD 1194 L W+ + RL V K +W+K + L+ + E + L++ + Sbjct: 23156 LAWEKPLYDGGSRLTGYVLEACKAGTERWMK---------VVTLKPTVLEHTVTSLNEGE 23206 Query: 1195 HGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMK 1254 ++ ++++G + D L + S P K + P G ++ + Sbjct: 23207 QYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTIDLSTMPQKTIHVPAGRPVELVIP 23264 Query: 1255 YF-TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEI 1305 +W +K+ SE + + ++A L I E T +D G+YT E+ Sbjct: 23265 IAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23316 Score = 182 bits (462), Expect = 2e-45 Identities = 157/621 (25%), Positives = 254/621 (40%), Gaps = 75/621 (12%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 LV P R P A W+ L+ES+ + A L+ D G YTL + + Sbjct: 23261 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23320 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDR 421 G + + + + D G P P+ + DA + ++W+PP +P+ GY V++ Sbjct: 23321 GTTSETIKVIILDKP----GPPTGPIKIDEIDATS--ITISWEPPELDGGAPLSGYVVEQ 23374 Query: 422 CEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPL 481 + W+ +++ + + T L EG Y+FRV A N GI Sbjct: 23375 RDAHRPGWLPVSESVTR-STFKFTRLTEGNEYVFRVAATNRFGIGS-------------- 23419 Query: 482 DLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDP 541 LQ+ +E I ++PGPP + ++SR+ + L+W PP G Sbjct: 23420 ---YLQSEVIECRSSI-----------RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ 23465 Query: 542 LM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 + Y +E+ V + W RVN + V RY L EG Y RV + N G +PS + Sbjct: 23466 VTGYIVERKEVRADRWVRVN-KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23524 Query: 601 SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEP 658 PI A D P P + T+TSV + W P+ E + GY ++ + W Sbjct: 23525 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23584 Query: 659 CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY--- 715 CN P + + L G +Y FRV A NA G E ++ +KV L P + Sbjct: 23585 CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDER 23644 Query: 716 ---GITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTV 772 GI + +T+ K F PI + + +++ + + + ++ I Sbjct: 23645 YQEGIFVRQGGVIRLTIPIKGKPF----PICKWTKEGQDISKRAMIATSETHTELVIKEA 23700 Query: 773 DGLTEGSLYEF--------KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEV 824 D G+ Y+ K + + IG P+ P GP L + ++ Sbjct: 23701 DRGDSGT-YDLVLENKCGKKAVYIKVRVIGSPNSPE-------------GP---LEYDDI 23743 Query: 825 RDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 + S+ + W+ P G + + GY ++ RE W T++ L V L++ Y Sbjct: 23744 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTS-LVVKGLKENVEYH 23802 Query: 885 FRVRAVNANGVGKPSDTSEPV 905 FRV A N G+ KP + EPV Sbjct: 23803 FRVSAENQFGISKPLKSEEPV 23823 Score = 182 bits (461), Expect = 3e-45 Identities = 173/685 (25%), Positives = 271/685 (39%), Gaps = 56/685 (8%) Query: 238 VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS----SMIPYTHFDVQFLEKFGVTFRREGE 293 VS N V GD FR + +S S P T D K + R G+ Sbjct: 22499 VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 22558 Query: 294 TVTLKCTMLVTPDLK---RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 VT++ + D + +P+ W + D L + + + +A+ + D Sbjct: 22559 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22618 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G YTL + + G S + V D+ PG L ++ + W P Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKVLDS-------PGPCGKLTVSRVTQEKCTLAWSLPQEDG 22671 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y V+R E NWV + Y VT L + YIFRVRAVN G Sbjct: 22672 GAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAVNKYG------ 22724 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 V +E E +A +P PP + ++++ Sbjct: 22725 ----------------PGVPVESEPIVA------RNSFTIPSPPGIPEEVGTGKEHIIIQ 22762 Query: 531 W-EPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W +P + G + Y ++K S W RVN V R V LMEG Y FRV + N Sbjct: 22763 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22822 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G SEPSE ++ I ++ + P P TK S+ + W +P ++ D++GY ++ Sbjct: 22823 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLE 22882 Query: 648 CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 T+ W + + I F V L G++Y FRV AVN GMSE S+ I+ Sbjct: 22883 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVE 22942 Query: 707 ALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK 766 + +P L ++ G P K+ + + ++++ S Sbjct: 22943 RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY 23002 Query: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826 ++L VD + ++ I A N +G + PGP + EV Sbjct: 23003 -SLLIVDKVNRYDAGKYTIEAENQSG-------KKSATVLVKVYDTPGPCPSVKVKEVSR 23054 Query: 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFR 886 S+ + W+ P G +PV+ Y V+ RE + TV + Y ++S L +G Y FR Sbjct: 23055 DSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLY-RISGLVEGTMYYFR 23113 Query: 887 VRAVNANGVGKPSDTSEPVLVEARP 911 V N G+G+P +TS+ VLV P Sbjct: 23114 VLPENIYGIGEPCETSDAVLVSEVP 23138 Score = 181 bits (460), Expect = 4e-45 Identities = 159/669 (23%), Positives = 274/669 (40%), Gaps = 82/669 (12%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ PG P + + D R V + W P S V GY ++ +V + W +CN Sbjct: 23531 DPIAP--PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 23588 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR--RLQAVHLEG 493 P KI +Y +T L +G Y FRV A N+ G P+ V V + L+ L + EG Sbjct: 23589 PTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEG 23648 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGS 553 I + Q G ++ P G + + + W T G+D I K Sbjct: 23649 ---IFVRQG---GVIRLTIPIKG-------KPFPICKW---TKEGQD-----ISK----- 23682 Query: 554 GSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHG----------LSEPSEITSPI 603 R T+ + + G S + ++ N+ G + P+ P+ Sbjct: 23683 ----RAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23738 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 + D+ V SV V W P + D+LGY ++ W + Sbjct: 23739 EYDDIQV---------------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23783 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT-LL 720 + G + VV GL +Y FRV A N G+S+ + + + + L P P +L Sbjct: 23784 RVRGTS-LVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVL 23842 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + S++L W PK GGS + GYY++++E W N + T+ TV GL + Sbjct: 23843 DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAE 23902 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G+ E S SE C+ +P +L + S+ + W+ P G Sbjct: 23903 YQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSISKDSVTLQWEKPECDG 23961 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + GY+V++R+ W N+ ++ + L + Y FRV A N G+ +P Sbjct: 23962 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24021 Query: 901 TSEPVLVEARPG--------TKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 T+ + + G K+++ + E + + + D W + +E+ Sbjct: 24022 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD---IKWYRFGKELIQ 24078 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 ++K+ + G L + ++ED G Y+ ++++ V + E +L+ + Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGEVETSSKLLLQATPQF 24131 Query: 1013 NPTIPLKSE 1021 +P PLK + Sbjct: 24132 HPGYPLKEK 24140 Score = 179 bits (453), Expect = 2e-44 Identities = 155/603 (25%), Positives = 260/603 (43%), Gaps = 78/603 (12%) Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGA---- 382 +W ++ G L + E + +R V++ G S+ S +DP++ Sbjct: 7532 EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS-----EPSDPVLCREKLYP 7586 Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 P P L+ + ++ + W P SP+ Y V++ +V W Q D VK K Sbjct: 7587 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKC 7645 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 VT L EG Y+FRV A N+ G S + + D+V A D Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT-------------------- 7685 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNA 561 PGPP + ++++ +V L WEPP G P+ Y IEK W + Sbjct: 7686 -------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG- 7737 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +TA + V D++EG F+V + N G+ PSE T + +D T PS P + + Sbjct: 7738 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 7797 Query: 622 RNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH-GLTTGE 678 + + + W P+ ++GY+V+ C GT W N +PI +F V G+ + Sbjct: 7798 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 7857 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQ---AALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 +Y+ RV+AVNA+G+SE S+ S+ + + T+ + I ++ +G +++ VP Sbjct: 7858 EYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVI--EGEKLSI--PVPF 7913 Query: 736 FSGGSPILGYYLDKREVHH------KNWHEVNSSPSKPTILTVDGLTEGSLYEFKI---- 785 + P + ++ D +EV KN H +++ P + D E K+ Sbjct: 7914 RAVPVPTVSWHKDGKEVKASDRLTMKNDH-ISAHLEVPKSVRADAGIYTITLENKLGSAT 7972 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 A++N+ IG P GP D+ ++ +S + W+ P + G +P+ Sbjct: 7973 ASINVKVIGLP-----------------GPCKDIKASDITKSSCKLTWEPPEFDGGTPIL 8015 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 Y ++ RE +I V + V DL Y FRV+AVN G G+ + PV Sbjct: 8016 HYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV 8074 Query: 906 LVE 908 + + Sbjct: 8075 IAQ 8077 Score = 177 bits (450), Expect = 5e-44 Identities = 166/627 (26%), Positives = 257/627 (40%), Gaps = 66/627 (10%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK- 441 PG P + D + V + W P S ++GYFV+ C++ + WV+CN AP +I + Sbjct: 12696 PGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12752 Query: 442 -YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 Y TGL E Y FR A + IS PS SD V L A ++ ++++ Sbjct: 12753 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL---------AENVPPRIDLSVA 12803 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVN 560 L G + A+ + +SW+ KD + K G + N Sbjct: 12804 MKSLL--TVKAGTNVCLDATVFGKPMPTVSWK------KDGTLL---KPAEGIKMAMQRN 12852 Query: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 T +F + S + + + N G T ++ D P P V Sbjct: 12853 LCTL------ELFSVNRKDSGDYTITAENSSG---SKSATIKLKVLDK---PGPPASVKI 12900 Query: 621 SRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE 678 ++ ++ W+ P + ++ Y VD W + + V L G Sbjct: 12901 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVS-ATVPITSCSVEKLIEGH 12959 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI----TLLNCDGHSMTLGWKVP 734 +Y FR+ A N G+ + V A P P G + N MT+ WK P Sbjct: 12960 EYQFRICAENKYGVGD-----PVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPP 13014 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 GGSPI GY L+KRE NW +VN P L GL EG+ YEF++ A+N AG G Sbjct: 13015 ADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPG 13074 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 +PSD S+ P PA+ + R +S+ + W P Y G SP+ GY V+ + Sbjct: 13075 KPSDASKAAYARDPQYPPGPPAFPKVYDTTR-SSVSLSWGKPAYDGGSPIIGYLVEVKRA 13133 Query: 855 DAGEWITVN--QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLV 907 D+ W+ N Q R+ +V+ L + Y FRV AVN G PSD + +L+ Sbjct: 13134 DSDNWVRCNLPQNLQKTRF-EVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13192 Query: 908 EARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVG 962 P E+ A + + + G + + TW K + D I++ Sbjct: 13193 ---PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD 13249 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L +N +K D G Y +++ ++ G Sbjct: 13250 FDTFLRCENVNKYDAGKYILTLENSCG 13276 Score = 176 bits (445), Expect = 2e-43 Identities = 164/628 (26%), Positives = 264/628 (42%), Gaps = 59/628 (9%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + + R+ V + W P + GY V++ ++ + +W++ N V C + Sbjct: 13780 PGKP---EVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAF 13836 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 VT L EG Y FR+RA N+AG IS PS ++ + D E E + Sbjct: 13837 TVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD------------EYEAPTIVLD 13884 Query: 502 DDLEGDAQVPGPPTGV--HASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRV 559 ++ + T V S + + SW + GKD I + + + + + Sbjct: 13885 PTIKDGLTIKAGDTIVLNAISILGKPLPKSSW---SKAGKDIRPSDITQ-ITSTPTSSML 13940 Query: 560 NAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV--VPSAPGR 617 + A R A + ++ + + ++ VTV VP PG Sbjct: 13941 TIKYATRK-------------------DAGEYTITATNPFGTKVEHVKVTVLDVPGPPGP 13981 Query: 618 VLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLT 675 V S + + W P + + Y ++ LW + + I R V L Sbjct: 13982 VEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLI 14040 Query: 676 TGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPK 735 G +YIFRV AVN G E Q S+ +K+ P P + N ++ T+ WK P Sbjct: 14041 QGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14099 Query: 736 FSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGE 795 GGS I GY++++RE W +P V GL EGS YEF+++A N AGIG Sbjct: 14100 DDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGP 14159 Query: 796 PSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREED 855 PS+ S+ + P PGP + + S + W P Y G ++GY V+ ++ Sbjct: 14160 PSEASDSVLMKDAAYP-PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14218 Query: 856 AGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGT 913 WI + T TA R + V DLQ + Y FR+ A+N GVG+P+ + +VE Sbjct: 14219 DEAWIK-DTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAP 14277 Query: 914 K-EISAGVDEQGNIYLGFDCQ-----EMTDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 E+ A + + G + + A + TW K + I+ R IE + L Sbjct: 14278 DFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLL 14335 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ D G + +++ + G S FV Sbjct: 14336 IIPECNRYDTGKFVMTIENPAGKKSGFV 14363 Score = 174 bits (442), Expect = 4e-43 Identities = 154/640 (24%), Positives = 249/640 (38%), Gaps = 84/640 (13%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P + +++ + V W PP + GYF+++ E + WV N + + + Sbjct: 11899 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 11958 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 V L Y FRV+A N GI PS S V A DP++ Sbjct: 11959 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE-------------------- 11998 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE-KSVVGSGS----W 556 PGPPT + +++ + L W P G P++ Y +E + + S W Sbjct: 11999 -------PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051 Query: 557 QRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--- 613 +R NA + + V L E + Y FRV + N+ G+ P+E+ I+ +++ P Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111 Query: 614 -------------APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN 660 P R+ A + + V W + + + VD L P + Sbjct: 12112 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNS 12171 Query: 661 HKPIGYNRFVVHGLTTGEQYIF-RVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITL 719 + + GE+ +F V+ ++ G + + SDV K Sbjct: 12172 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT--------------- 12216 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGS 779 S + W P+ GGS + Y ++KRE K W V K T V L G+ Sbjct: 12217 ------SCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKK-TSFHVTNLVPGN 12269 Query: 780 LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYS 839 Y F++ AVN G G P+D + + EP P L E+ S + W P+ Sbjct: 12270 EYYFRVTAVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRD 12328 Query: 840 GSSPVSGYFVDFREED--AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G + + GY +REE+ A W + + L V+ L++GK Y FRV A NA GV Sbjct: 12329 GGAKIDGYITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSL 12386 Query: 898 PSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDA-----SQFTWCKSYEEISD 952 P + + EA+ + EQ I G + W K +E+ Sbjct: 12387 PREAEG--VYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVT 12444 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 + S L +K+ ++D G YS++ ++ G + Sbjct: 12445 SSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDT 12484 Score = 173 bits (439), Expect = 1e-42 Identities = 157/607 (25%), Positives = 254/607 (41%), Gaps = 62/607 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + + + S + + + L + + D G Y+L + G + Sbjct: 12431 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12490 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V DA G P P D+ D + D ++W P S + Y V++C+V +WV Sbjct: 12491 VMDAP----GPPQPPFDIS--DIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVT 12544 Query: 432 CNDAPVKI-CKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490 + K C+ V L G+ YIFRVRA N GIS P Sbjct: 12545 ALASVTKTSCR--VGKLIPGQEYIFRVRAENRFGISEP---------------------- 12580 Query: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKS 549 L K +A + VP P ++++++ + ++W+ P G P++ Y IE+ Sbjct: 12581 LTSPKMVAQFPFG------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERK 12634 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 S W + N T VRS Y L+EG Y FR+ + N+ G S PS+ T + A+ + Sbjct: 12635 ERNSLLWVKAN-DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MP 12692 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKP--IG 665 V P PG+ TK++V + W RPKH+ ++GY+V+ C + W CN P I Sbjct: 12693 VDP--PGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12750 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC--- 722 + GL QY FR A AV +S S+ SD + + A P + + + Sbjct: 12751 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 12810 Query: 723 -DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781 G ++ L V F P + + D + ++ + T L + + Sbjct: 12811 KAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT-LELFSVNRKDSG 12867 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 ++ I A N +G S+ + + +PGP + ++ ++ W+ P+ G Sbjct: 12868 DYTITAENSSG-------SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 12920 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 S ++ Y VD RE W V+ T V L +G Y FR+ A N GVG P T Sbjct: 12921 SEITNYIVDKRETSRPNWAQVSATVPITS-CSVEKLIEGHEYQFRICAENKYGVGDPVFT 12979 Query: 902 SEPVLVE 908 EP + + Sbjct: 12980 -EPAIAK 12985 Score = 172 bits (437), Expect = 2e-42 Identities = 163/628 (25%), Positives = 259/628 (41%), Gaps = 61/628 (9%) Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQ-ASLSFSHLHKDDE 350 GET L+ + P P W +D L+E+ Q +L + D Sbjct: 18225 GETFVLEADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G Y L++ + GG + V D G P P+ + A + Y+ W PP Sbjct: 18280 GQYILKLSNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDG 18333 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + + Y +++ E +W Q + V+ Y VT L G YIFRV AVN GI P Sbjct: 18334 GANISHYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE 18392 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 S V A +P + PGPP+ S I+++ +V++ Sbjct: 18393 -SGPVTACNPY---------------------------KPPGPPSTPEVSAITKDSMVVT 18424 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W P G + Y +EK W + N +T + R V L EG SY FRV + N Sbjct: 18425 WARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAEN 18483 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVD 647 G+ EPSE + +A D P P + +++SV + W +P ++ + GY V+ Sbjct: 18484 AAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVE 18543 Query: 648 CCVAGTNLWEPCNHKPIGY--NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ 705 A + W C P G +F V L +Y FR+ A+N+ G+ E + + Q Sbjct: 18544 VKEAAADEWTTCT-PPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQ 18602 Query: 706 AALTVPSHPYGITLLNCD--GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 + P L S TL V P + + + + + EV SS Sbjct: 18603 ERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS 18662 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823 T+L +D +T + + N +G S+ + P +LT E Sbjct: 18663 ---FTMLVIDNVTRFDSGRYNLTLENNSG-------SKTAFVNVRVLDSPSAPVNLTIRE 18712 Query: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTY 883 V+ S+ + W+ P+ G + ++ Y V+ RE + T+ T + ++ +LQ+G +Y Sbjct: 18713 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTF-RIENLQEGCSY 18771 Query: 884 VFRVRAVNANGVGKPSDTSEPVLVEARP 911 FRV A N G+G P++T+EPV V P Sbjct: 18772 YFRVLASNEYGIGLPAETTEPVKVSEPP 18799 Score = 172 bits (436), Expect = 2e-42 Identities = 149/603 (24%), Positives = 243/603 (40%), Gaps = 66/603 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R P W R++ + ++ G LS + ++D G Y L++ + G SA Sbjct: 17554 RPTPEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG--SKSA 17609 Query: 369 FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNN 428 F+ V+ D PG P +L + +D + W+PP + V Y +D+ E Sbjct: 17610 FVTVKVLD-----TPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17664 Query: 429 WVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488 + + K + V L EG Y FRV A N G+ P DAV A +P Sbjct: 17665 YANVSSKCSKT-SFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP-------- 17715 Query: 489 VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIE 547 P PP V +++S+ L WE P G ++ Y +E Sbjct: 17716 ----------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17753 Query: 548 KSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQD 607 G+ W V + V L G+ Y FRV + N G S+P + P+ A+D Sbjct: 17754 MQPKGTEKWSIVAESKVCNA---VVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17810 Query: 608 VTVVPSA-----PGRVLASRNTKTSV-VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH 661 +T+ PS + A + K + V+ RP + G L + Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN---------ISWVKDGEPLKQTTRV 17861 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLL 720 V + G + F V A + + E+ + V L P P G + Sbjct: 17862 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV---LEKPGPPVGPVRFD 17918 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 + + W+ P ++GG I Y ++KR+ WH V+++ ++ TI + L G+ Sbjct: 17919 EVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTE 17977 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 Y+F+I A N G P D + EPGP + +++ W PV G Sbjct: 17978 YQFRIFAENRYGKSAPLDSKA--VIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDG 18035 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + + GY ++ +E+++ W+ +N+T + K + L +G Y F+V A N G+GKPS Sbjct: 18036 GTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18095 Query: 901 TSE 903 SE Sbjct: 18096 VSE 18098 Score = 172 bits (435), Expect = 3e-42 Identities = 170/703 (24%), Positives = 284/703 (40%), Gaps = 123/703 (17%) Query: 353 YTLRIVSRG--GVSDHSA-FLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTT 409 Y R+ + GV + S +F R D L PG P + + D +R V + W P Sbjct: 18475 YEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYD 18532 Query: 410 TESPVMGYFVDRCEVGTNNWVQCNDAP-VKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468 +PV GY V+ E + W C ++ ++ VT L E Y FR+ A+NS G+ P Sbjct: 18533 GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEP 18592 Query: 469 SRVSDAVAALDPL---------DLRRLQA----------VHLEGEKEIAIYQDDLEG--- 506 + + +V A + + DLR++ V ++G E + + EG Sbjct: 18593 ATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18652 Query: 507 -DAQV--------------------------------------------PGPPTGVHASE 521 AQ+ P P + E Sbjct: 18653 DRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18712 Query: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++ V LSWEPP G + Y +EK ++ + + + + +L EG S Sbjct: 18713 VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT--FRIENLQEGCS 18770 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE-- 638 Y FRVL++N +G+ P+E T P++ V+ P PGRV T+ + ++W++P+ + Sbjct: 18771 YYFRVLASNEYGIGLPAETTEPVK---VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGG 18827 Query: 639 EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQ- 697 + GY V+ G+ W C + + GLT GE+Y+FRV AVN G S+ Q Sbjct: 18828 SKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQL 18885 Query: 698 ----ESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVH 753 + I+++ ++ +P H + + L VP + + D + + Sbjct: 18886 GVPVIARDIEIKPSVELPFHTFNVKARE------QLKIDVPFKGRPQATVNWRKDGQTL- 18938 Query: 754 HKNWHEVNSSPSKP-TILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE 812 K VN S SK T L++ ++ + +++ N AG S + Sbjct: 18939 -KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG-------SITVPITIIVLDR 18990 Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872 PGP + EV S+ + W P Y G +S Y V+ +E + W V+Q A + Sbjct: 18991 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSI 19049 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSE-----PVLVEARPGTKEI----------- 916 K+ L G Y FRV A N G S++S P PGT ++ Sbjct: 19050 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVT 19109 Query: 917 -SAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958 V++ G+ +G+ E + S W K+ + + D + K+ Sbjct: 19110 WQVPVNDGGSRVIGYHL-EYKERSSILWSKANKILIADTQMKV 19151 Score = 171 bits (434), Expect = 4e-42 Identities = 161/542 (29%), Positives = 240/542 (44%), Gaps = 50/542 (9%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DPL G P +P L + + + + WK P + SP+ GY +++ ++ + N Sbjct: 8793 DPL--GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8850 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 + V L E + Y FRV+AVN G S PS + V D + + + G+ Sbjct: 8851 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT 8910 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 + + A V G P + E S+N V+ E PT D L I K V Sbjct: 8911 IKVKAGEPVHIPADVTGLP--MPKIEWSKNETVI--EKPT----DALQ--ITKEEV---- 8956 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV--PS 613 R A+T + P+ + E K + V ++NR G S + V V PS Sbjct: 8957 -SRSEAKTELSIPK----AVREDKG-TYTVTASNRLG--------SVFRNVHVEVYDRPS 9002 Query: 614 APGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNL--WEPCNHKPIGYNRF 669 P + + S + WD P ++ Y +D A WE + + R+ Sbjct: 9003 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAV-EKRY 9061 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 + L QY FRV+AVN G+S+ +SD + +Q +P P +L SM + Sbjct: 9062 GIWKLIPNGQYEFRVRAVNKYGISDEC-KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLV 9120 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSP-----SKPTILTVDGLTEGSLYEFK 784 W P +GGSPI GY+L+KRE W V+ +P K V L EG Y+F+ Sbjct: 9121 SWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFR 9180 Query: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844 A+N AGIG PS+PS+ P PGP + +S+ + WK P G SP+ Sbjct: 9181 AMAINAAGIGPPSEPSDPEVAGDPIFP-PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPI 9239 Query: 845 SGYFVDFREEDAGEWITVNQ----TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 GY V+ +EE +W VN+ TT V +L++ + Y FRV+AVN G +PSD Sbjct: 9240 KGYIVEMQEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEPSD 9297 Query: 901 TS 902 T+ Sbjct: 9298 TT 9299 Score = 171 bits (433), Expect = 5e-42 Identities = 165/648 (25%), Positives = 245/648 (37%), Gaps = 83/648 (12%) Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL--LKESKWTKMFFGEGQA 338 L+ GV + G+T+ L+ + P P W +D L S K+ + Sbjct: 11708 LKLSGVLTVKAGDTIRLEAGVRGKPF-----PEVAWTKDKDATDLTRSPRVKIDTRADSS 11762 Query: 339 SLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDY 398 S + + D G Y + + G FV A V PG +L+ D + D Sbjct: 11763 KFSLTKAKRSDGGKYVVTATNTAGS-------FVAYATVNVLDKPGPVRNLKIVDVSSDR 11815 Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVR 458 V W PP + Y +++CE W A V VT L EG YIFRVR Sbjct: 11816 CTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRLIEGNEYIFRVR 11874 Query: 459 AVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVH 518 A N G P+ +A + PG P Sbjct: 11875 AENKIGTGPPTESKPVIA----------------------------KTKYDKPGRPDPPE 11906 Query: 519 ASEISRNYVVLSWEPPT-PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLME 577 +++S+ + + W PP GK YF+EK S W VN ++A+ R V +L+ Sbjct: 11907 VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVN-KSAIPERRMKVQNLLP 11965 Query: 578 GKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH 637 Y FRV + N G+ EPS + P+ A+D P P TK S+ + W +P + Sbjct: 11966 DHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVY 12025 Query: 638 E--EDLLGYYVD-----CCVAGTNLWEPCN-HKPIGYNRFVVHGLTTGEQYIFRVKAVNA 689 + ++GY V+ + W+ CN + F V L ++Y FRV A N Sbjct: 12026 DGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ 12085 Query: 690 VGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK 749 VG+ ++ + IK + L P ++ K+ G PI + + + Sbjct: 12086 VGIGRPAELKEAIKPKEILEPPEIDLDASMR-----------KLVIVRAGCPIRLFAIVR 12134 Query: 750 -REVHHKNWHEVN----------SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSD 798 R W +V L + T ++ + VN AG Sbjct: 12135 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG------ 12188 Query: 799 PSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + PGP DL +V TS + W P G S V+ Y V+ RE D Sbjct: 12189 -EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKT 12247 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 W TV + V++L G Y FRV AVN G G P+D +PVL Sbjct: 12248 WSTVTPEVKKTSF-HVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVL 12294 Score = 171 bits (433), Expect = 5e-42 Identities = 160/655 (24%), Positives = 271/655 (41%), Gaps = 62/655 (9%) Query: 364 SDHSAFLFVRDADPL-VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC 422 +++ L + ADP+ V P P + D R+ V ++W P S ++ Y V+ Sbjct: 16614 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16673 Query: 423 EVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLD 482 + W +C A VK + +T L +G Y+FRV AVN G S P ++ + A D + Sbjct: 16674 AKHSEKWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLV- 16730 Query: 483 LRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL 542 + + + + Y + D ++ P +G R ++W Sbjct: 16731 ------IEPDVKPAFSSYSVQVGQDLKIEVPISG-------RPKPTITWT---------- 16767 Query: 543 MYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 K + R+N ++ ++ + + + + AN G + T+ Sbjct: 16768 -----KDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-----QKTAS 16817 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCN 660 I+ + G V + S+ + W+ P + + Y V T +W+ + Sbjct: 16818 IEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVS 16877 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 + V L TG +Y FR+ A N G S + ESD I Q P P Sbjct: 16878 -ATVARTTLKVTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPGPPGTPFAT 16935 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 SM + W P +GGSP++GY+L+++E + W +VN + T L EG Sbjct: 16936 AISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIE 16995 Query: 781 YEFKIAAVNLAGIGEPSDPSEHF----KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 YEF++ A N+ G+G+ S SE + C+ PEP V+ + + W P Sbjct: 16996 YEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEP--------IMVKRNEITLQWTKP 17047 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-V 895 VY G S ++GY V+ R+ G W+ + T VS L + + Y FRV A NA G + Sbjct: 17048 VYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAI 17107 Query: 896 GKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-------QFTWCKSYE 948 KPSD++ P+ + IS + I + +A W + + Sbjct: 17108 SKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDK 17167 Query: 949 EISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EI + R +I+ + L +K+ + D G Y + S+ G S SF ++ + L+R Sbjct: 17168 EIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG-SKSFPVNVKVLDR 17221 Score = 170 bits (431), Expect = 8e-42 Identities = 168/685 (24%), Positives = 281/685 (41%), Gaps = 86/685 (12%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R +P W +D LK++ + L +KDD G YT+ + G + Sbjct: 17837 PVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 17896 Query: 365 DHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCE 423 + + V + PG P+ ++ + + D+V+++W+PP T + Y V++ + Sbjct: 17897 TENLSVIVLEK-------PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 17949 Query: 424 VGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDL 483 T W + A V +T L G Y FR+ A N G S P Sbjct: 17950 TTTTTWHMVS-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP--------------- 17993 Query: 484 RRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM 543 L+ + I Y + PGPP + IS++ +++ W P G ++ Sbjct: 17994 -------LDSKAVIVQYP------FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKII 18040 Query: 544 -YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP 602 Y +E+ S W ++N +T ++ ++ L EG Y F+V + N G+ +PS+++ Sbjct: 18041 GYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSEC 18099 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCN 660 A+D P P ++ +RN +V ++W +P ++ + GY V+ W + Sbjct: 18100 FVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18156 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPS----HPY 715 + F V GL ++Y FRV A NA G SE S S I + + P+ Y Sbjct: 18157 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18216 Query: 716 GITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWH-EVNSSPSKPTILTV 772 ++ G + L + G PI + + D +E+ E+ S+ K T++ Sbjct: 18217 KDVIVVHAGETFVLEADI----RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVK 18272 Query: 773 DGL-TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 D + T+G Y K++ V G S P + PGP L V Sbjct: 18273 DCIRTDGGQYILKLSNVG----GTKSIP-----ITVKVLDRPGPPEGPLKVTGVTAEKCY 18323 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W P+ G + +S Y ++ RE W V+ A Y KV+ L G Y+FRV AV Sbjct: 18324 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY-KVTKLLPGNEYIFRVMAV 18382 Query: 891 NANGVGKPSDTS-----EPVLVEARPGTKEISA------------GVDEQGNIYLGFDCQ 933 N G+G+P ++ P P T E+SA VD+ G G+ Sbjct: 18383 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-IL 18441 Query: 934 EMTDASQFTWCKSYEEISDDERFKI 958 E D W K ++ D R ++ Sbjct: 18442 EKRDKEGVRWTKCNKKTLTDLRLRV 18466 Score = 169 bits (429), Expect = 1e-41 Identities = 139/511 (27%), Positives = 223/511 (43%), Gaps = 34/511 (6%) Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 G +YIFRV+AVN G+ E ESD + + A P P + +SMT+ W P Sbjct: 20536 GNEYIFRVRAVNKYGIGE-PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIA 20594 Query: 737 SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 GGS I GY+L+KR+ W +V + T V GLTE S Y++++ AVN AG G Sbjct: 20595 DGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPF 20654 Query: 797 SDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDA 856 S+PSE +K A + PGP + + +S+ + W PVY G S V+GY V+ R+ + Sbjct: 20655 SEPSEFYKA-ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEE 20713 Query: 857 GEWITVNQ--TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTK 914 EW TV+ Y+ VS+L+ G Y FRV AVN G G+P + +EPV + Sbjct: 20714 EEWTTVSTKGEVRTTEYV-VSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 20772 Query: 915 EISAGVDEQGNIY--LGFDCQEM-----TDASQFTWCKSYEEISDDERFKIETVGDHSKL 967 EI V + ++ G D Q + TW K + + D R+ IE S L Sbjct: 20773 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 20832 Query: 968 YLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSN-EIKN------------P 1014 + + D G Y +++ + G S + + L+ A ++K+ P Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPP 20892 Query: 1015 TIPLKSELAYEIFDK--GRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072 I S + + +K R W H S++ I D R+ + GI Sbjct: 20893 LIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI--DLSEKTPFFFRVLAENEIGI 20950 Query: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132 E ++ I D K + +I K + + + ++G Sbjct: 20951 GEPCETTEPVK-AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGE 21009 Query: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKW 1163 + H +++ CE+ +V+ K+++V ++ Sbjct: 21010 QTWSHAGISKTCEI----EVSQLKEQSVLEF 21036 Score = 169 bits (429), Expect = 1e-41 Identities = 160/636 (25%), Positives = 264/636 (41%), Gaps = 66/636 (10%) Query: 302 LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRG 361 L P + +P W +D + LKES++ + E + +LS + K+ G YT+ Sbjct: 21086 LELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV------ 21139 Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMD-LQCHDANRDYVIVTWKPPNTTTESPVMGYFVD 420 + D++ + G P P ++ + D VI++W P + Y ++ Sbjct: 21140 -ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21198 Query: 421 RCEVGTNNW-VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD 479 + E NW + C+ K P L + Y FRVRA N G+S+P S VA Sbjct: 21199 KRETSQTNWKMVCSSVARTTFKVP--NLVKDAEYQFRVRAENRYGVSQPLVSSIIVA--- 21253 Query: 480 PLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGK 539 + ++PGPP ++ + + L+W+ P G Sbjct: 21254 -------------------------KHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGG 21288 Query: 540 DPLMYF-IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSE 598 + F +EK S WQ+VN + + Y L+EG Y FRV + N GLS PS+ Sbjct: 21289 SEVTGFHVEKKERNSILWQKVNT-SPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSD 21347 Query: 599 ITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLW 656 + A P P + +R T + ++W+ P + ++GY ++ G W Sbjct: 21348 PSKFTLAVSPVDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIE-KRQGNERW 21403 Query: 657 EPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPY 715 CN + ++ V GL+ G++Y FR+ A NAVG +S SQ S +I + P + Sbjct: 21404 VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEF 21463 Query: 716 GITLLNCDGHSMTLG--WKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILT 771 G DG + G ++ G P+ + ++ D E+ + E+ T L Sbjct: 21464 GPEYF--DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS-TSLF 21520 Query: 772 VDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLV 830 V T + + A N +G S + + PG + F + + Sbjct: 21521 VRDATRDHRGVYTVEAKNASG-------SAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573 Query: 831 MLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 + W AP+ G +P++ Y ++ RE W + A Y + L G Y FRV AV Sbjct: 21574 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSAV 21632 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNI 926 N GVG+P D S+PV+ + + T + G+ E NI Sbjct: 21633 NKFGVGRPLD-SDPVVAQIQ-YTVPDAPGIPEPSNI 21666 Score = 169 bits (427), Expect = 2e-41 Identities = 159/618 (25%), Positives = 253/618 (40%), Gaps = 50/618 (8%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICK 441 AP P L D + V + W P S + GY ++ G++ W VK + Sbjct: 14467 APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITT--VKGLE 14524 Query: 442 YPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V L EG Y F+V AVNSAG S P R S V + L L + + IA Sbjct: 14525 CVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAG 14583 Query: 502 DDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNA 561 D+++ + V G P ++W+ +G L QRVN Sbjct: 14584 DNIKVEIPVLGRPKPT-----------VTWK----KGDQILK-----------QTQRVNF 14617 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621 +T S + + + S + + + N G E ++ + IQ D+ P+ P + Sbjct: 14618 ETTATSTILNINECVRSDSGPYPLTARNIVG--EVGDVIT-IQVHDIPGPPTGP--IKFD 14672 Query: 622 RNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 + V WD P+++ + Y V+ + W I + LTTG + Sbjct: 14673 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLE 14731 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG 739 Y FRVKA N G+ + ++ VP P + SMT+ W P GG Sbjct: 14732 YQFRVKAQNRYGVGPGITSACIV-ANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGG 14790 Query: 740 SPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 SPILGY+++++E + W V+ + I GLT+G YEF++ A N+AG +PS P Sbjct: 14791 SPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKP 14850 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859 SE P PG L + ++ + W P Y+G ++ Y V+ R+ G W Sbjct: 14851 SEPMLALDPIDP-PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW 14906 Query: 860 ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEPVLVEARPGTKEISA 918 + N + VS L + Y FRV A NA G + PS+ S+ + +I Sbjct: 14907 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 14966 Query: 919 GVDEQGNIYL--GFDCQEMTDAS-----QFTWCKSYEEISDDERFKIETVGDHSKLYLKN 971 V + + L G + D S W K +E+ + +I+ + L K+ Sbjct: 14967 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKD 15026 Query: 972 PDKEDLGTYSVSVSDTDG 989 + D G Y+++ ++ G Sbjct: 15027 STRRDSGAYTLTATNPGG 15044 Score = 168 bits (426), Expect = 3e-41 Identities = 145/581 (24%), Positives = 244/581 (41%), Gaps = 63/581 (10%) Query: 335 EGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDA 394 +G++ L + D GLY +++ + G++ + V D PG P++ D Sbjct: 8264 KGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDI 8316 Query: 395 NRDYVIVTWKPPNTTTESPVMGYFVDRCE--VGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 + V+ W+PP S ++ Y +++ + + W+ + ++ CKY VT L EG+ Sbjct: 8317 RKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCKYSVTKLIEGKE 8375 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 Y+FRVRA N G P VS + A DP G P Sbjct: 8376 YLFRVRAENRFGPGPPC-VSKPLVAKDPF------------------------GPPDAPD 8410 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +++ N +++ W P G L Y++EK V S W RVN ++ + + + V Sbjct: 8411 KPI---VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVN-KSLLNALKANV 8466 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 L+EG +YVFRV + N G + S + P A D + P P + + T++ ++W Sbjct: 8467 DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIELEW 8525 Query: 633 DRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 + P +++GY+VD + GTN W C K I ++ V + G Y RV AVNA Sbjct: 8526 EPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAA 8585 Query: 691 GMSENSQESDVIKVQAALTVPSHPYGITL-LNCDGHSMTLGWK---VPKFSGGSPILGYY 746 G + V + P P + L ++ G + K +P G P+ Sbjct: 8586 GEGPPGETQPV-----TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8640 Query: 747 LDKREVH-HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 K E K+ +++ +K ++ D L + + I A N G S+ Sbjct: 8641 WTKEEGELDKDRVVIDNVGTKSELIIKDALRKDH-GRYVITATNSCG-------SKFAAA 8692 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 PGP DL ++ W P G S ++G+ ++ ++ W +T Sbjct: 8693 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET 8752 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 + ++ L +G+ Y FRV A N G G P + P+L Sbjct: 8753 ERSK--CDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PIL 8790 Score = 167 bits (424), Expect = 5e-41 Identities = 156/610 (25%), Positives = 250/610 (40%), Gaps = 58/610 (9%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P L R +P W + D +LK+++ L+ + + D G Y L +R V Sbjct: 14591 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL--TARNIVG 14648 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + ++ D + G P P+ + + D+V +W PP P+ Y V+ + Sbjct: 14649 EVGDVITIQVHD--IPGPPTGPIKFD--EVSSDFVTFSWDPPENDGGVPISNYVVEMRQT 14704 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + WV+ ++ Y T L G Y FRV+A N G+ P S + A P Sbjct: 14705 DSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPF--- 14759 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 +VPGPP + ++++ + +SW P G P++ Sbjct: 14760 ------------------------KVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILG 14795 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ WQ V ++ V + L +G +Y FRV++ N G S+PS+ + P+ Sbjct: 14796 YHVERKERNGILWQTV-SKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 14854 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNH 661 A D PG+ + T+ +V ++W +P++ + Y V+ W N Sbjct: 14855 LALDPI---DPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANF 14911 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVPSHPYGI--- 717 I N F V GLT Y FRV A NA G +S S+ SD I + + P + Sbjct: 14912 SNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFK 14971 Query: 718 -TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLT 776 T++ G + L V P + + D +E+ E+ + ++ D T Sbjct: 14972 DTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS-T 15028 Query: 777 EGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAP 836 + + A N G + F + P P P L EV V+ W P Sbjct: 15029 RRDSGAYTLTATNPGGFAK-----HIFNVKVLDRPGP-PEGPLAVTEVTSEKCVLSWFPP 15082 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 + G + + Y V RE W V + LKV+ L +G Y+FRV AVN GVG Sbjct: 15083 LDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTK-LKVTKLLKGNEYIFRVMAVNKYGVG 15141 Query: 897 KPSDTSEPVL 906 +P + SEPVL Sbjct: 15142 EPLE-SEPVL 15150 Score = 167 bits (424), Expect = 5e-41 Identities = 158/611 (25%), Positives = 256/611 (41%), Gaps = 64/611 (10%) Query: 309 RVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSA 368 R +P W +D + LK++ + +LS HKDD G Y + + + G S Sbjct: 16759 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 16818 Query: 369 FLFVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTN 427 + D DP P P+ D + + + ++W PP T + Y V + + T Sbjct: 16819 EIVTLDKPDP-----PKGPVKFD--DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 16871 Query: 428 NWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQ 487 W A V VT L G Y FR+ A N G Q Sbjct: 16872 VW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYG----------------------Q 16908 Query: 488 AVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFI 546 + LE + +A Y + PGPP A+ IS++ +V+ W P G P++ Y + Sbjct: 16909 SFALESDPIVAQYP------YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 16962 Query: 547 EKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ 606 E+ S W +VN +T + ++ +L EG Y FRV + N G+ + S+ + A+ Sbjct: 16963 ERKERNSILWTKVN-KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 17021 Query: 607 DVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPI 664 D P P ++ RN + +QW +P ++ + GY V+ W + + Sbjct: 17022 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 17078 Query: 665 GYNRFVVHGLTTGEQYIFRVKAVNAVG-MSENSQESDVIKVQAALTVP----SHPYGITL 719 +F V GLT ++Y FRV A NA G +S+ S + I + + +P + T+ Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 17138 Query: 720 LNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL-TEG 778 + G + L + P + + +E+ E+ ++ K ++ D + +G Sbjct: 17139 VVNAGETFRL--EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17196 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY-DLTFCEVRDTSLVMLWKAPV 837 Y + A N+AG S+ F + PGP + V + W P+ Sbjct: 17197 GQYILR--ASNVAG-------SKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPL 17247 Query: 838 YSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 G S +S Y V+ RE W V N LKV+ L +G YVFR+ AVN GVG+ Sbjct: 17248 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIMAVNKYGVGE 17306 Query: 898 PSDTSEPVLVE 908 P + S PVL++ Sbjct: 17307 PLE-SAPVLMK 17316 Score = 167 bits (423), Expect = 7e-41 Identities = 161/636 (25%), Positives = 268/636 (42%), Gaps = 74/636 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P+ L + R V + W P T + Y V++ ++ W++ N + + ++ Sbjct: 14863 PGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 14919 Query: 443 PVTGLFEGRSYIFRVRAVNSAG-ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQ 501 V+GL E +Y FRV A N+AG IS PS SDA+ D ++ +++ V ++ + + + Sbjct: 14920 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIK-VDVKFKDTVILKA 14978 Query: 502 DD---LEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + LE D PPT + W + I+ + S Sbjct: 14979 GEAFRLEADVSGRPPPT-------------MEWSKDGKELEGTAKLEIK---IADFSTNL 15022 Query: 559 VNAQTAVR-SPRYAVFDLMEG--KSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 VN + R S Y + G ++F V +R G E Sbjct: 15023 VNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-------------------- 15062 Query: 616 GRVLASRNTKTSVVVQWDRPKHEEDL-LGYYV-----DCCVAGTNLWEPCNHKPIGYNRF 669 G + + T V+ W P + + +Y+ +A TN+ + + Sbjct: 15063 GPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV-----ASEVQVTKL 15117 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V L G +YIFRV AVN G+ E + V+ V P P + SM + Sbjct: 15118 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNP-YGPPDPPKNPEVTTITKDSMVV 15176 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W P GGS I+ Y +++R+ + W + N V GLTEG YEF+I A N Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15236 Query: 790 LAGIGEPSDPSEHFK-CEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848 AGI PS S +K C+ T+ +PGP + + +S+ + W P+Y G S ++GY Sbjct: 15237 AAGISAPSPTSPFYKACD--TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYM 15294 Query: 849 VDFR--EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVL 906 V+ EED + +T A Y ++ L + + Y R+ A+N+ G+G+P+ Sbjct: 15295 VEIALPEEDEWQIVTPPAGLKATSY-TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15353 Query: 907 VEARPGTKEISAGVDEQGNIYLGFDCQ-------EMTDASQFTWCKSYEEISDDERFKIE 959 E R EI D + + + C + A + W + + E D + IE Sbjct: 15354 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15411 Query: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 + ++ L + N ++ D G Y ++V ++ G S+FV Sbjct: 15412 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFV 15447 Score = 167 bits (422), Expect = 9e-41 Identities = 157/616 (25%), Positives = 246/616 (39%), Gaps = 58/616 (9%) Query: 309 RVQPRAEWYR---DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSD 365 R P+ W + D+V+ K ++ + A L + +DD G Y+L +V+ G + Sbjct: 12136 RPAPKVTWRKVGIDNVVRKG----QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG--E 12189 Query: 366 HSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVG 425 + F+ VR D PG DL+ D + V+W PP S V Y V++ E Sbjct: 12190 KAVFVNVRVLD-----TPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 12244 Query: 426 TNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 W VK + VT L G Y FRV AVN G P+ V V A DPL Sbjct: 12245 RKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL---- 12299 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 P PP + +E+++N L+W PP G + + Sbjct: 12300 -----------------------SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12336 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQA 605 I R + V+ V L EGK Y FRV + N G+S P E +A Sbjct: 12337 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12396 Query: 606 QDVTVVPS--APGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKP 663 ++ + P P ++ K + H D V ++L HK Sbjct: 12397 KEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL---AVHKA 12453 Query: 664 IGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCD 723 + ++ +T + + + A N+ G ++Q+ V+ V A P P+ I+ + D Sbjct: 12454 DSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVV-VMDAPGPPQPPFDIS--DID 12508 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + +L W +P GGS I Y ++K +V +W +S +K T V L G Y F Sbjct: 12509 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIF 12567 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSP 843 ++ A N GI EP + + P + +V + + W P G SP Sbjct: 12568 RVRAENRFGISEPLTSPK--MVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSP 12625 Query: 844 VSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE 903 + GY ++ +E ++ W+ N T + + L +G Y FR+ A+N G PS +E Sbjct: 12626 IIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTE 12685 Query: 904 PVLVEA---RPGTKEI 916 V PG E+ Sbjct: 12686 YVTARMPVDPPGKPEV 12701 Score = 166 bits (420), Expect = 2e-40 Identities = 155/611 (25%), Positives = 243/611 (39%), Gaps = 63/611 (10%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P +W + D L + ++ + SLS + D G Y L+ + G + + Sbjct: 16076 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + A + + WKPP S ++ Y V+R E W Sbjct: 16136 VLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDIINYIVERRETSRLVWTV 16189 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 DA V+ VT L EG Y FR+ AVN G+ P S+ V A +P Sbjct: 16190 V-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEPVVAKNPF---------- 16237 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWE-PPTPRGKDPLMYFIEKSV 550 VP P + ++++ +++ WE P + G + L Y +EK Sbjct: 16238 -----------------VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRD 16280 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 W R + + + R V L+E Y FRV + N GLSEPS ++ +A D Sbjct: 16281 KEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16339 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P P T++SV + W +P ++ ++ GY V+ C W C P G N+ Sbjct: 16340 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCT-PPTGINK 16398 Query: 669 --FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHS 726 V L +Y FR+ A+N G+ E++ I V+ L P + L Sbjct: 16399 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKI---- 16454 Query: 727 MTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIA 786 + +GGS L + R W +V+ I+ V S + Sbjct: 16455 ------INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV----TSSFTSLVLD 16504 Query: 787 AVNLAGIG------EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 VN G E S ++ + P P +L E+ S+ + W+ P+ G Sbjct: 16505 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDG 16564 Query: 841 SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 S + Y V+ RE + V N + K+ LQ+G +Y FRV A N G+G P+ Sbjct: 16565 GSKIKNYIVEKREATRKSYAAVVTNCHKNSW-KIDQLQEGCSYYFRVTAENEYGIGLPAQ 16623 Query: 901 TSEPVLVEARP 911 T++P+ V P Sbjct: 16624 TADPIKVAEVP 16634 Score = 165 bits (418), Expect = 3e-40 Identities = 154/563 (27%), Positives = 231/563 (41%), Gaps = 60/563 (10%) Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 DP+ AP P + D + + W PP S V GY V+ E G W + D Sbjct: 9920 DPI---APPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 9976 Query: 436 PVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEK 495 V+ K VTGL EG Y FRVRAVN AGI P V+D + D L Sbjct: 9977 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRL-------------- 10022 Query: 496 EIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGS 555 DL+ DA V VHA + R +S +PP + + + + + Sbjct: 10023 ----VSPDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPT-----VTWNMNERTLP--- 10069 Query: 556 WQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP 615 Q +T S + + V+ +L+ N G + + I DV VP Sbjct: 10070 -QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIV------DVLDVPGPV 10122 Query: 616 GRVLASRN-TKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672 G + N T S + W P+ + + Y ++ + W P + N V Sbjct: 10123 GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQ 10181 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWK 732 GL G+ Y FR+ A N++GM + S+ + ++ +TVP P + + +++TL W Sbjct: 10182 GLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN 10241 Query: 733 VPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792 PK+ GGS I+ Y L+ R + + +H+V + TV GL EG YE++++AVN+ G Sbjct: 10242 PPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10301 Query: 793 IGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPV----YSGS-SPVSGY 847 G+PS ++ C+ P P L F RD + + +A YSG P + Sbjct: 10302 QGKPSFCTKPITCKDELAP---PTLHLDF---RDKLTIRVGEAFALTGRYSGKPKPKVSW 10355 Query: 848 FVDFRE--EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 F D + ED I T A +K GK V V N G + Sbjct: 10356 FKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV-----VVENSTGSRKGFCQVN 10410 Query: 906 LVEARPGTKEISAGVDEQGNIYL 928 +V+ RPG DE Y+ Sbjct: 10411 VVD-RPGPPVGPVSFDEVTKDYM 10432 Score = 162 bits (410), Expect = 2e-39 Identities = 182/806 (22%), Positives = 327/806 (40%), Gaps = 96/806 (11%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP I ++ T + +L + G P P ++WY+ G + Q+ KY++ S+ H Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR---KYKMSSDGRTH 24091 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272 TL + + +D Y+ +ATN G+V T++ ++++ P Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA----------------------TP 24129 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H EK+ + G T+ L + P P W+ LL+ S+ + Sbjct: 24130 QFHPGYPLKEKY---YGAVGSTLRLHVMYIGRP-----VPAMTWFHGQKLLQNSENITIE 24181 Query: 333 FGEGQASLSFSHLH-KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQC 391 E L ++ K G Y +++ + G D + ++D TG P+ ++ Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG----PIVIEA 24237 Query: 392 HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGR 451 N +++WKPP S + Y V++CE Q + + + + L E Sbjct: 24238 LLKNS--AVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24295 Query: 452 SYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVP 511 Y FRV A N+ GIS P VS V P + P Sbjct: 24296 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------P 24328 Query: 512 GPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRY 570 G P + ++++ V++W+PP G + Y++EK W V + +R + Sbjct: 24329 GAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE-IRETVF 24387 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-DVTVVPSAPGRVLASRNTK--TS 627 +V +L+EG Y FRV N G SE SEI+ PI + DV + L + N + ++ Sbjct: 24388 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSN 24447 Query: 628 VVVQWDRPKHEEDLLGYYVDCC-VAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 + H + ++ +Y + L GY++ ++ +T + +++V+A Sbjct: 24448 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRA 24507 Query: 687 VNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC-DGHSMTLGWKVPKFSGGSPILGY 745 N G S + S ++V A + +P G+ ++ G +++ K+P P++ + Sbjct: 24508 TNQGG-SVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITW 24564 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + + + ++V + S +++ +G+ + + A N GI + + Sbjct: 24565 QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT-------V 24617 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 E P P + +V S+ + W P G S ++ Y V+ A W+ V Q Sbjct: 24618 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ- 24676 Query: 866 TTANRYLKVSDLQQGKT-YVFRVRAVNANGVGKPSDTSEPVLV-EARPGTKEISAGVDEQ 923 RY ++ GKT Y FRV A N G+ KPS+ SEP + E + VDE Sbjct: 24677 ARETRYTVINLF--GKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDET 24734 Query: 924 GNIYLGFDCQEMTDASQFTWCKSYEE 949 + MT AS + + YE+ Sbjct: 24735 REV-------SMTKASHSSTKELYEK 24753 Score = 161 bits (408), Expect = 4e-39 Identities = 155/638 (24%), Positives = 255/638 (39%), Gaps = 72/638 (11%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG P +L D + +V + W+ P+ SP + Y V+R G+++W + + +K Y Sbjct: 11604 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHY 11663 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALD----PLDLRRLQAVHLEGEKEIA 498 V E + Y FRV+ N G S + + V D LDL+ + ++ I Sbjct: 11664 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIR 11723 Query: 499 IYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQR 558 + +A V G P + ++W +K R Sbjct: 11724 L-------EAGVRGKP-----------FPEVAWTK-------------DKDATDLTRSPR 11752 Query: 559 VNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRV 618 V T S ++++ + V + N G A V PG V Sbjct: 11753 VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG---------SFVAYATVNVLDKPGPV 11803 Query: 619 LASRNTKTSVV------VQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 RN K V V WD P+ + ++ Y ++ C +W + + V Sbjct: 11804 ---RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTV 11860 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 L G +YIFRV+A N +G ++ VI + P P + MT+ Sbjct: 11861 TR-LIEGNEYIFRVRAENKIGTGPPTESKPVI-AKTKYDKPGRPDPPEVTKVSKEEMTVV 11918 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 W P++ GG I GY+L+K+E H W VN S + V L Y+F++ A N Sbjct: 11919 WNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENE 11978 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 GIGEPS PS + P PGP + + S+ + W PVY G +P+ GY V+ Sbjct: 11979 IGIGEPSLPSRPVVAKDPIEP-PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVE 12037 Query: 851 FREEDAGE-----WITVNQTT-TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 R + A W N + V+ L + + Y FRV A N G+G+P++ E Sbjct: 12038 MRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEA 12097 Query: 905 VLVE--ARPGTKEISAGVDEQGNIYLG-----FDCQEMTDASQFTWCKSYEEISDDERFK 957 + + P ++ A + + + G F A + TW K + + + + Sbjct: 12098 IKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQ 12156 Query: 958 IETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFV 995 ++ V + L + N ++D G YS+++ + G + FV Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12194 Score = 161 bits (407), Expect = 5e-39 Identities = 157/614 (25%), Positives = 257/614 (41%), Gaps = 62/614 (10%) Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 P + R P W++D+V LK++ E + L+ ++D G Y +++ + G + Sbjct: 15673 PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + + V D G P P+ + + D + ++W PP S + Y V++ + Sbjct: 15733 IETLNVIVLDKP----GPPTGPVKMD--EVTADSITLSWGPPKYDGGSSINNYIVEKRDT 15786 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 T W Q A V L G Y FR+ A N G Sbjct: 15787 STTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAENRYG-------------------- 15825 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRGKDPLM 543 ++ +L E +A Y +VPGPP + SR+ + + W EP + G + Sbjct: 15826 --KSTYLNSEPTVAQYP------FKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 15877 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E+ S W ++N +T + ++ L EG Y FRV + N G+ +PS+++ Sbjct: 15878 YHLERKERNSILWVKLN-KTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY 15936 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D P P ++ +RN SV +QW +P ++ + GY V+ W + Sbjct: 15937 VARDPCDPPGRPEAIIVTRN---SVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 15993 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGM-SENSQESDVIKVQAALTVP----SHPYG 716 I F V GL +Y FRV A NA G+ SE S+ + I + + P Y Sbjct: 15994 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYK 16053 Query: 717 ITLLNCDGHSMTLGWKVPKFSGGSPI--LGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774 T++ G S +KV G PI + + +E+ + E+ S+ ++ D Sbjct: 16054 DTIVVHAGES----FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDA 16109 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 + S + + A N+AG + S + P P P + V + WK Sbjct: 16110 VRVDS-GNYILKAKNVAG-----ERSVTVNVKVLDRPGP-PEGPVVISGVTAEKCTLAWK 16162 Query: 835 APVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG 894 P+ G S + Y V+ RE W TV KV+ L +G Y FR+ AVN G Sbjct: 16163 PPLQDGGSDIINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 16221 Query: 895 VGKPSDTSEPVLVE 908 VG+P + SEPV+ + Sbjct: 16222 VGEPLE-SEPVVAK 16234 Score = 160 bits (406), Expect = 6e-39 Identities = 164/646 (25%), Positives = 251/646 (38%), Gaps = 84/646 (13%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 EGE +++ P P W++D +K S M A L + D Sbjct: 7903 EGEKLSIPVPFRAVP-----VPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410 G+YT+ + ++ G + S + V G PG D++ D + +TW+PP Sbjct: 7958 GIYTITLENKLGSATASI-------NVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDG 8010 Query: 411 ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 +P++ Y ++R E G ++ K+ + V L Y FRV+AVN G Sbjct: 8011 GTPILHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIE 8069 Query: 471 VSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLS 530 + + V A DP Q P PP V + + ++ Sbjct: 8070 LKNPVIAQDP---------------------------KQPPDPPVDVEVHNPTAEAMTIT 8102 Query: 531 WEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSAN 589 W+PP G +M Y IEK G W+R N + V Y L EGK Y FRV + N Sbjct: 8103 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCN-EHLVPILTYTAKGLEEGKEYQFRVRAEN 8161 Query: 590 RHGLSEPSEITSPIQAQDVTVVPSAPGRVL------------ASRNTKTSVVVQWDR--- 634 G+SEPS T P +A D P R AS + + W + Sbjct: 8162 AAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDEN 8221 Query: 635 ---PKHEEDLLGYYVDCCVAGTNLWEP----------CNHKPIGYNRFVVHGLTTGEQYI 681 P+ + V EP ++ G ++ V + + Sbjct: 8222 VIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGL 8281 Query: 682 FRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSP 741 + +K N G+++ V L P P + S+ W+ P GGS Sbjct: 8282 YMIKVENDHGIAKAPCTVSV------LDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSE 8335 Query: 742 ILGYYLDKRE--VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 I+ Y L+K++ W V S+ + +V L EG Y F++ A N G G P Sbjct: 8336 IINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVS 8394 Query: 800 SEHFKCEAWTMPEPGPAYDLTFCE-VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGE 858 + + P+ A D E V S+++ W P +G SP+ GY+++ RE ++ Sbjct: 8395 KPLVAKDPFGPPD---APDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTH 8450 Query: 859 WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 W VN++ V L +G TYVFRV A NA G GK S S+P Sbjct: 8451 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 8496 Score = 158 bits (399), Expect = 4e-38 Identities = 128/444 (28%), Positives = 198/444 (44%), Gaps = 35/444 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 P P + +I+++ V L+WEPP G PL Y +EK V +W +V V Sbjct: 6991 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV--MDFVTDLE 7048 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V DL++GK Y+F+V + N+ G EP+ + P+ VP P V T S+ Sbjct: 7049 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 7108 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + WD PK++ + GY V+ C G++ W C +P+ + V GL G+ Y +RVKA+ Sbjct: 7109 LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPVAETKMEVTGLEEGKWYAYRVKAL 7167 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV--PKFSGGSPILGY 745 N G S+ S+ ++ I+ P + LL G ++ G K+ P G P Sbjct: 7168 NRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL--AGLTVKAGTKIELPATVTGKPEPKI 7225 Query: 746 YLDKREVHHKNWHE--VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 K ++ K + + P K T+ VD + I AVN+ G Sbjct: 7226 TWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGTYIIEAVNVCGRATA------- 7277 Query: 804 KCEAWTMPEPGP--AYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWIT 861 E + +PGP A+D+T +V + S ++ W P G S ++ Y V+ R D+ W Sbjct: 7278 VVEVNVLDKPGPPAAFDIT--DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 7335 Query: 862 VNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVD 921 ++ T + K + L K Y+FRV A N GVG+P V+A P T + D Sbjct: 7336 LSSTVKDTNF-KATKLIPNKEYIFRVAAENMYGVGEP--------VQASPITAKYQ--FD 7384 Query: 922 EQGNIYLGFDCQEMTDASQFTWCK 945 G DA TWC+ Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCE 7408 Score = 157 bits (397), Expect = 7e-38 Identities = 168/638 (26%), Positives = 259/638 (40%), Gaps = 70/638 (10%) Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V+ A+P P P + D ++ + W+ P S V+GY V+ GT W Sbjct: 17710 VKAAEP-----PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSI 17764 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 ++ K+C VTGL G+ Y FRV+A N G S P + V A D L ++ L Sbjct: 17765 VAES--KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD---LTIQPSLKL 17819 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVV 551 +DL+ + V G P +SW + +PL Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPN-----------ISWV----KDGEPLK-------- 17856 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF---RVLSANRHGLSEPSEITSPIQAQDV 608 RVN + S V + EG F V + N G + +E S I V Sbjct: 17857 ---QTTRVNVEETATS---TVLHIKEGNKDDFGKYTVTATNSAGTA--TENLSVI----V 17904 Query: 609 TVVPSAP-GRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIG 665 P P G V + VV+ W+ P + + Y V+ T W + + Sbjct: 17905 LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS-ATVA 17963 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 + L TG +Y FR+ A N G S VI VQ P P + + Sbjct: 17964 RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI-VQYPFKEPGPPGTPFVTSISKD 18022 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKI 785 M + W P GG+ I+GY+L+++E + W ++N +P + T GL EG YEFK+ Sbjct: 18023 QMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKV 18082 Query: 786 AAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVS 845 +A N+ GIG+PS SE F P P + + ++ + WK P Y G S ++ Sbjct: 18083 SAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV----ITRNNVTLKWKKPAYDGGSKIT 18138 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG-VGKPSDTSEP 904 GY V+ ++ G W+ + T VS L + + Y FRV A NA G +PSD+S Sbjct: 18139 GYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSG- 18197 Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEM---------TDASQFTWCKSYEEISDD-E 954 + AR +A +D + + E W K +E+ + Sbjct: 18198 -AITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAA 18256 Query: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSS 992 R +I++ + L +K+ + D G Y + +S+ G S Sbjct: 18257 RMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18294 Score = 151 bits (382), Expect = 4e-36 Identities = 175/732 (23%), Positives = 295/732 (40%), Gaps = 58/732 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP +I + V+ WEPP G ++ Y +EK + + + +R + Sbjct: 8305 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8364 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y+V L+EGK Y+FRV + NR G P ++ P+ A+D P AP + + T S++ Sbjct: 8365 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8423 Query: 630 VQWDRPK-HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVN 688 V+W+ PK + +LGY+++ + W N + + V GL G Y+FRV A N Sbjct: 8424 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8483 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 A G + S SD ++ P P + + ++ L W+ P F+GG I+GY++D Sbjct: 8484 AAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVD 8542 Query: 749 KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAW 808 K+ V W K TV + EG+ Y+ +++AVN AG G P + E Sbjct: 8543 KQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-- 8600 Query: 809 TMPEPGPAYDLTFCEVRDTSLVMLWK-----APVYSGSSPVSGYFVDFREEDAGEWITVN 863 P+ PA +L V+ +M K A V P + + E D + N Sbjct: 8601 --PQEPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN 8657 Query: 864 QTTTANRYLKVSDLQQGKTYV----------FRVRAVNANGVGKPSDTSEPVLVEARPGT 913 T + +K + + YV F V V P +PV+ + Sbjct: 8658 VGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL 8717 Query: 914 KEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPD 973 S D+ G+ GF E DA TW + E ER K + G L+ + Sbjct: 8718 LNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIE----TERSKCDITG-----LLEGQE 8767 Query: 974 KEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVR 1033 + + V + G P E+ ++A+ + + PT P L Y K + Sbjct: 8768 YK----FRVIAKNKFGCG-----PPVEIGPILAV-DPLGPPTSP--ERLTYTERTKSTIT 8815 Query: 1034 F-WLQAEHLSPDASYRFIINDREVSDSEIHRIK---CDKATGIIEMVMDRFSIENEGTYT 1089 W + +II R + R+ C + ++E + + E Sbjct: 8816 LDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAV 8875 Query: 1090 VQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLV 1149 +I + + ++V+ D ++ R + ++ + E +H + + + Sbjct: 8876 NEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA---GEPVH--IPADVTGLPM 8930 Query: 1150 CKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQD 1209 K+ +K ETV + D L T+ + EL IPK ++D G Y T + G Sbjct: 8931 PKIEWSKNETVIE-KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSV 8989 Query: 1210 VSILEIAGKVYD 1221 + + +VYD Sbjct: 8990 FRNVHV--EVYD 8999 Score = 151 bits (382), Expect = 4e-36 Identities = 151/584 (25%), Positives = 239/584 (40%), Gaps = 82/584 (14%) Query: 347 KDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPP 406 + D G Y + + G +A + V D PG +DL+ NR ++ W P Sbjct: 8671 RKDHGRYVITATNSCGSKFAAARVEVFDV-------PGPVLDLKPVVTNRKMCLLNWSDP 8723 Query: 407 NTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGIS 466 S + G+ ++R + + W Q + C +TGL EG+ Y FRV A N G Sbjct: 8724 EDDGGSEITGFIIERKDAKMHTWRQPIETERSKC--DITGLLEGQEYKFRVIAKNKFGCG 8781 Query: 467 RPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG---VHASEIS 523 P + + A+DPL GPPT + +E + Sbjct: 8782 PPVEIG-PILAVDPL------------------------------GPPTSPERLTYTERT 8810 Query: 524 RNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYV 582 ++ + L W+ P G P+ Y IEK ++RVN + + + V +L E + Y Sbjct: 8811 KSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLC-PTTSFLVENLDEHQMYE 8869 Query: 583 FRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH-EEDL 641 FRV + N G SEPS + + QD V P+ R+ +T + V+ P H D+ Sbjct: 8870 FRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDT---IKVKAGEPVHIPADV 8925 Query: 642 LGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGE--------------QYIFRVKAV 687 G + N E KP + ++ E + + V A Sbjct: 8926 TGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 8983 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYL 747 N +G + +V PS P + + + S L W P +GGS I Y + Sbjct: 8984 NRLGSVFRNVHVEV------YDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9037 Query: 748 DKREVHHK--NWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 DKR+ K W EV ++ + + L YEF++ AVN GI + + Sbjct: 9038 DKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9096 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 + + +P P P + + LV W P+ +G SP++GY+++ REE + W V++ Sbjct: 9097 DPYRLPGP-PGKPKVLARTKGSMLVS-WTPPLDNGGSPITGYWLEKREEGSPYWSRVSRA 9154 Query: 866 TTANRYLK-----VSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 LK V L +G Y FR A+NA G+G PS+ S+P Sbjct: 9155 PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9198 Score = 150 bits (379), Expect = 9e-36 Identities = 109/444 (24%), Positives = 202/444 (45%), Gaps = 39/444 (8%) Query: 563 TAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASR 622 T + + + +G ++++ N+HG +E I + + V PG V Sbjct: 6550 TTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF-----INLKVIDV----PGPVRNLE 6600 Query: 623 NTKT---SVVVQWDRPKHE--EDLLGYYVD-------CCVAGTNLWEPCNHKPIGYNRFV 670 T+T V + W+ P + ++GY V+ V T+ E C F Sbjct: 6601 VTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE--------FT 6652 Query: 671 VHGLTTGE-QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTL 729 V GL G +Y+FRV A N VG E + + ++ ++ VP P +T+ + + ++L Sbjct: 6653 VTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSL 6712 Query: 730 GWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVN 789 W+ P++ GG+ I Y ++ R+ W + ++ TV + EG Y F++ A N Sbjct: 6713 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQN 6772 Query: 790 LAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849 G+G+PS + K A + P P +LT + +S+ + W+ P+ G SP+ GY + Sbjct: 6773 RIGVGKPSAATPFVKV-ADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6831 Query: 850 DFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA 909 + EE WI N KV+ L++G Y++RV A N GV PS+ P+ + Sbjct: 6832 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 6891 Query: 910 R--PGTKEISAGVDEQGNIYLGFDCQEMTDASQF-----TWCKSYEEISDDERFKIETVG 962 T ++SA D + + + ++ + TWC + + +R K++T+ Sbjct: 6892 AFVEPTMDLSAFKDGL-EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 6950 Query: 963 DHSKLYLKNPDKEDLGTYSVSVSD 986 +++L + ++ D G Y++ + + Sbjct: 6951 AYAELVISPSERSDKGIYTLKLEN 6974 Score = 150 bits (378), Expect = 1e-35 Identities = 138/520 (26%), Positives = 208/520 (40%), Gaps = 88/520 (16%) Query: 375 ADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD--RCEVGTNNWVQC 432 +DPL P P L+ + ++ + W PP + + GY E + W + Sbjct: 12296 SDPL--SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEY 12353 Query: 433 NDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAA----LDPLDLRRLQ- 487 + VK VTGL EG+ Y FRV A N+ G+S P A L P L Q Sbjct: 12354 S--VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI 12411 Query: 488 -------------------------------------AVHLEGEKEIAIYQDDLEGDA-- 508 AVH I I +D D+ Sbjct: 12412 TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 12471 Query: 509 ---------------------QVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YF 545 PGPP S+I + LSW P G + Y Sbjct: 12472 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYI 12531 Query: 546 IEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSP-IQ 604 +EK V G W V A +V V L+ G+ Y+FRV + NR G+SEP +TSP + Sbjct: 12532 VEKCDVSRGDW--VTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMV 12587 Query: 605 AQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHK 662 AQ VPS P ++ K + V WDRP + ++GY ++ + LW N Sbjct: 12588 AQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT 12647 Query: 663 PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNC 722 + + GL G +Y FR+ A+N G S S+ ++ + + + P P +++ Sbjct: 12648 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKP---EVIDV 12704 Query: 723 DGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSK--PTILTVDGLTEGSL 780 +++L W PK GGS I+GY+++ ++ W N++P + T GL E + Sbjct: 12705 TKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQ 12764 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLT 820 Y+F+ A I PS+PS+ A +P P DL+ Sbjct: 12765 YQFRAIARTAVNISPPSEPSDPVTILAENVP---PRIDLS 12801 Score = 149 bits (376), Expect = 2e-35 Identities = 199/866 (22%), Positives = 327/866 (37%), Gaps = 118/866 (13%) Query: 150 ISRAPEIL--VRLRSHTVWER-MSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 I APEI V LR+ + + V++ +G P P V W KD + A +Y IE Sbjct: 20768 ILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA---RYSIE 20824 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 + L I + +DT Y N +G P Sbjct: 20825 NTDSSSLLTIPQVTRNDTGKYILTIENG----------------------------VGEP 20856 Query: 267 LSSMIPYTHFDVQFL-EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKE 325 SS + D +K V G TVTL + P + P + + + Sbjct: 20857 KSSTVSVKVLDTPAACQKLQVKHVSRG-TVTL---LWDPPLIDGGSPIINYVIEKRDATK 20912 Query: 326 SKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGA 385 W+ + +S SF + ++ + R+++ + +P+ A Sbjct: 20913 RTWSVV--SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEP---CETTEPVKAAEVPA 20967 Query: 386 PM-DLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPV 444 P+ DL D+ + VI++W P+ S + Y V+R G W + K C+ V Sbjct: 20968 PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGIS--KTCEIEV 21025 Query: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504 + L E FRV A N G+S P + P+ ++ L I + DL Sbjct: 21026 SQLKEQSVLEFRVFAKNEKGLSDP-------VTIGPITVKEL----------IITPEVDL 21068 Query: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTA 564 + +PG V I N + E P P + +++ + Sbjct: 21069 ---SDIPGAQVTVR---IGHN---VHLELPYKGKPKPSISWLKDGL-------------P 21106 Query: 565 VRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ--AQDVTVV----PSAP-GR 617 ++ + F E K + + HG + + + A +TV+ PS P G Sbjct: 21107 LKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP 21166 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHK----PIGYNRFVVHG 673 + SV++ WD P ED G + C N K + F V Sbjct: 21167 IRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPN 21223 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 L +Y FRV+A N G+S+ S +I + +P P + N M+L W Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQ-PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDA 21282 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 P + GGS + G++++K+E + W +VN+SP GL EG Y+F++ A N AG+ Sbjct: 21283 PVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21342 Query: 794 GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE 853 PSDPS+ + P P Y +V ++ + W P+ G S + GY ++ R+ Sbjct: 21343 SSPSDPSKFTLAVSPVDPPGTPDY----IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ 21398 Query: 854 EDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP----------SDTSE 903 + W+ N T + V+ L G Y FR+ A NA G P D + Sbjct: 21399 GNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV 21457 Query: 904 PVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGD 963 P +VE G + + + G + + TW K EI +I V Sbjct: 21458 PPIVEF--GPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG 21515 Query: 964 HSKLYLKNPDKEDLGTYSVSVSDTDG 989 + L++++ ++ G Y+V + G Sbjct: 21516 STSLFVRDATRDHRGVYTVEAKNASG 21541 Score = 149 bits (376), Expect = 2e-35 Identities = 139/518 (26%), Positives = 220/518 (42%), Gaps = 56/518 (10%) Query: 511 PGPPTG-VHASEISRNYVVLSWEPPTPRG-KDPLMYFIEKSVVGSGSWQRVNAQTAVRSP 568 P P G + +I V +SW PP G D L Y +E+ V +W ++++ VR Sbjct: 23731 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR--VRGT 23788 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ---DVTVVPSAPGRVLASRNTK 625 V L E Y FRV + N+ G+S+P + P+ + + PS P VL TK Sbjct: 23789 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV--TK 23846 Query: 626 TSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFR 683 +SV + W RPK + + GYY++ T+ W N I + V GL +Y FR Sbjct: 23847 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 23906 Query: 684 VKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPIL 743 + A N VG+SE S S+ + + PS P + +L+ S+TL W+ P+ GG IL Sbjct: 23907 IIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEIL 23966 Query: 744 GYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 GY+++ R+ W + N K T+ GL E + YEF++ A N G+ P + Sbjct: 23967 GYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSI 24026 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 K + + PG E++D + + G + + R +W Sbjct: 24027 KTKLTSGEAPGIRK-----EMKDVTTKL--------GEAAQLSCQIVGRPLPDIKWYRFG 24073 Query: 864 QTTTANRYLKVSDLQQGKTYVFRV-----------RAVNANGVGKPSDTSEPVLVEARP- 911 + +R K+S G+T+ V + N VG+ +TS +L++A P Sbjct: 24074 KELIQSRKYKMS--SDGRTHTLTVMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQ 24130 Query: 912 -----GTKEISAGVD----EQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVG 962 KE G +Y+G M TW + + + E IE Sbjct: 24131 FHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAM------TWFHGQKLLQNSENITIENTE 24184 Query: 963 DHSKLYLKNPD-KEDLGTYSVSVSDTDGVSSSFVLDPE 999 ++ L +KN K G Y V +S+ G + +LD E Sbjct: 24185 HYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA-ILDVE 24221 Score = 147 bits (371), Expect = 7e-35 Identities = 164/689 (23%), Positives = 272/689 (39%), Gaps = 81/689 (11%) Query: 250 RGDEEPFRSVGLP-----IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 +G +P R +G+P I + S +P+ F+V+ E+ + +G Sbjct: 18877 KGRSDP-RQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKG------------ 18923 Query: 305 PDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 R Q W +D LKE+ + + SLS K+D G Y L + + G Sbjct: 18924 ----RPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 18979 Query: 365 DHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEV 424 + V D PG P ++ + + D + ++W PP + Y V++ E Sbjct: 18980 TVPITIIVLDR-------PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKET 19032 Query: 425 GTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLR 484 + W + A V + L G Y FRV A N G S S S VA Sbjct: 19033 TSTTWHIVSQA-VARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA-------- 19083 Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM- 543 E PGPP +++ ++++W+ P G ++ Sbjct: 19084 --------------------EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIG 19123 Query: 544 YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 Y +E S W + N + + + V L EG Y +RV + N G+ + S+ P+ Sbjct: 19124 YHLEYKERSSILWSKAN-KILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19182 Query: 604 QAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNH 661 A+D PG+ + T+ SV ++W +P ++ + GY V+ W CN+ Sbjct: 19183 PARDPC---DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNY 19239 Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAV-GMSENSQESDVIKVQAALTVPSHPYGITLL 720 I F V LT ++Y FRV A NA +SE S+ + I V+ + P + Sbjct: 19240 TNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFR 19299 Query: 721 NCDGHSMTLGWKVPKFSGGS--PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEG 778 + K+ G P++ + D E+ + E+ S+ + T+LTV Sbjct: 19300 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNH-TLLTVKDCIRR 19358 Query: 779 SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVY 838 ++ + N+AG S C+ P P PA L + + W P Sbjct: 19359 DTGQYVLTLKNVAG-----TRSVAVNCKVLDKPGP-PAGPLEINGLTAEKCSLSWGRPQE 19412 Query: 839 SGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 G + + Y V+ RE W T+ + KV+ L +G Y+FRV VN GVG+P Sbjct: 19413 DGGADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19471 Query: 899 SDT-----SEPVLVEARPGTKEISAGVDE 922 ++ +P V + P + EI++ E Sbjct: 19472 LESVAIKALDPFTVPSPPTSLEITSVTKE 19500 Score = 144 bits (364), Expect = 5e-34 Identities = 163/681 (23%), Positives = 264/681 (38%), Gaps = 79/681 (11%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P+ RD V LK + +++ D G Y + + G + + Sbjct: 20009 PKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV 20068 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G P P+ + D + V + W+PP S V Y + + E T W + Sbjct: 20069 VLDRP----GPPTGPVVIS--DITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20122 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 + A V V L G Y FR++A N GIS D +D + Sbjct: 20123 VS-ATVARTMMKVMKLTTGEEYQFRIKAENRFGIS------------DHIDSACVT---- 20165 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550 ++ PGPP+ + ++R + + W P G ++ Y +E Sbjct: 20166 ------------VKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKD 20213 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 S WQ+ N + +R+ + V + G Y FRV + N G+ +PS + P+ A D Sbjct: 20214 RNSILWQKAN-KLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC- 20271 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P V + +K SV + W +P + + GY V+ W + + + Sbjct: 20272 --EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20329 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPY-GITLLNCDGHSM 727 F++ GLT QY FRV A NAVG N S+V+ + P + L + Sbjct: 20330 FIISGLTQNSQYEFRVFARNAVGSISNP--SEVVGPITCIDSYGGPVIDLPLEYTEVVKY 20387 Query: 728 TLGWKVPKFSGGS----PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG--LTEGSLY 781 G V +G S P + +Y D +E+ V ++ +IL D L G Y Sbjct: 20388 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC-Y 20446 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 E K+ N G S + + P P P + F V + +LW+ P G Sbjct: 20447 ELKLR--NAMG-----SASATIRVQILDKPGP-PGGPIEFKTVTAEKITLLWRPPADDGG 20498 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 + ++ Y V+ RE W V++ + + + +G Y+FRVRAVN G+G+P ++ Sbjct: 20499 AKITHYIVEKRETSRVVWSMVSEHLE-ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20557 Query: 902 SEPVLVEA-----RPGTKEI------------SAGVDEQGNIYLGFDCQEMTDASQFTWC 944 V A PG E+ S + + G+ G+ E D W Sbjct: 20558 DSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY-FLEKRDKKSLGWF 20616 Query: 945 KSYEEISDDERFKIETVGDHS 965 K +E D R K+ + ++S Sbjct: 20617 KVLKETIRDTRQKVTGLTENS 20637 Score = 141 bits (355), Expect = 5e-33 Identities = 122/473 (25%), Positives = 210/473 (44%), Gaps = 49/473 (10%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+ ++ L WEPP G + Y I+K ++ V+++ + S Sbjct: 17619 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTS-- 17676 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V +L EG Y FRV++ N G+ P E ++A + PS PG+V + ++TS Sbjct: 17677 FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP---PSPPGKVTLTDVSQTSAS 17733 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ GT W + VV GL++G++Y FRVKA Sbjct: 17734 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC--NAVVTGLSSGQEYQFRVKAY 17791 Query: 688 NAVGMSEN-----SQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 N G S+ + + +Q +L +P + Y I G + + ++P P Sbjct: 17792 NEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQA----GEDLKI--EIPVIGRPRPN 17845 Query: 743 LGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 + + D + V + + T+L + + ++ + A N AG +E+ Sbjct: 17846 ISWVKDGEPLKQTTRVNVEETATS-TVLHIKEGNKDDFGKYTVTATNSAGTA-----TEN 17899 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 P P P + F EV +V+ W+ P Y+G +S Y V+ R+ W V Sbjct: 17900 LSVIVLEKPGP-PVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMV 17958 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE------ARPGTKEI 916 + T A +K++ L+ G Y FR+ A N G P D S+ V+V+ PGT + Sbjct: 17959 S-ATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIVQYPFKEPGPPGTPFV 18016 Query: 917 SA------------GVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFK 957 ++ V++ G +G+ E + + W K + D +FK Sbjct: 18017 TSISKDQMLVQWHEPVNDGGTKIIGYHL-EQKEKNSILWVKLNKTPIQDTKFK 18068 Score = 140 bits (353), Expect = 9e-33 Identities = 116/421 (27%), Positives = 187/421 (44%), Gaps = 32/421 (7%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGP + ++I+++ V L W+ P G + Y +EK S+ A T Sbjct: 14371 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS--TATTKCHKCT 14428 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 Y V L EG Y FRV++ N +G+ EP+E T P++A + PS P + TK++V Sbjct: 14429 YKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLNIMDITKSTVS 14485 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W +PKH+ + GY ++ G++ W + + VV LT GE+Y F+V AV Sbjct: 14486 LAWPKPKHDGGSKITGYVIEAQRKGSDQW--THITTVKGLECVVRNLTEGEEYTFQVMAV 14543 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI---TLLNCDGHSMTLGWKVPKFSGGSPILG 744 N+ G S + VI + + GI ++ G ++ + ++P P + Sbjct: 14544 NSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKV--EIPVLGRPKPTVT 14601 Query: 745 YYLDKREVHHKNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 + K + K VN + + TIL ++ + + A N+ G + + Sbjct: 14602 W--KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVG-----EVGDVI 14654 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 + +P P P + F EV + W P G P+S Y V+ R+ D+ W+ + Sbjct: 14655 TIQVHDIPGP-PTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14713 Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSE------PVLVEARPGTKEIS 917 T Y K + L G Y FRV+A N GVG P TS P V PGT +++ Sbjct: 14714 TTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANYPFKVPGPPGTPQVT 14771 Query: 918 A 918 A Sbjct: 14772 A 14772 Score = 136 bits (343), Expect = 1e-31 Identities = 112/417 (26%), Positives = 180/417 (43%), Gaps = 28/417 (6%) Query: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPR 569 PGPP + E+++ V L+W+PP G + Y +EK ++ V T Sbjct: 15455 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV--ATNCHKTS 15512 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVV 629 + V L EG SY FRVL+ N +G+ P+E ++A + P PG++ T+ SV Sbjct: 15513 WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASE---RPLPPGKITLMDVTRNSVS 15569 Query: 630 VQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 + W++P+H+ +LGY V+ G++ W C + + GL GE+Y FRV A Sbjct: 15570 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQ 15627 Query: 688 NAVGMSENSQESDVIKVQAALTVPSHPYGI-TLLNCDGHSMTLGWKVPKFSGGSPILGYY 746 N G+S+ Q S + + + P+ T G + + VP +P + ++ Sbjct: 15628 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKV--DVPFIGRPTPAVTWH 15685 Query: 747 LDKREVHHKNWHEVNS-SPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D V K VN+ S ++LT+ + + + N AG + E Sbjct: 15686 KD--NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG-----EAIETLNV 15738 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQT 865 P P P + EV S+ + W P Y G S ++ Y V+ R+ W V+ Sbjct: 15739 IVLDKPGP-PTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS-A 15796 Query: 866 TTANRYLKVSDLQQGKTYVFRVRAVNANGV-----GKPSDTSEPVLVEARPGTKEIS 917 T A +K L+ G Y FR+ A N G +P+ P V PGT ++ Sbjct: 15797 TVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15853 Score = 134 bits (337), Expect = 6e-31 Identities = 174/771 (22%), Positives = 294/771 (38%), Gaps = 127/771 (16%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT-LEINRADFDDTATYSA 229 ++L ++G P P+ +W K+G I + A + + HT L I AD D+ TY Sbjct: 23657 IRLTIPIKGKPFPICKWTKEGQDISKRA------MIATSETHTELVIKEADRGDSGTYDL 23710 Query: 230 VATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFR 289 V N G+ + V V IG P S P + D+Q + V++R Sbjct: 23711 VLENKCGKKAVYIKVRV----------------IGSPNSPEGPLEYDDIQ-VRSVRVSWR 23753 Query: 290 REGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349 + + +R P+A WY D ++ + SL L ++ Sbjct: 23754 PPADDGGADILGYILE--RREVPKAAWYTIDSRVRGT------------SLVVKGLKENV 23799 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCH-----DANRDYVIVTWK 404 E + + ++ G+S ++ +P+ P P + + D + V ++W Sbjct: 23800 EYHFRVSAENQFGISKP-----LKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWS 23854 Query: 405 PPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG 464 P S V GY+++R E T+ WV+ N + Y VTGL Y FR+ A N G Sbjct: 23855 RPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVG 23914 Query: 465 ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISR 524 +S S S+ V DP D P P + IS+ Sbjct: 23915 LSETSPASEPVVCKDPFD---------------------------KPSQPGELEILSISK 23947 Query: 525 NYVVLSWE-PPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVF 583 + V L WE P GK+ L Y++E G +W++ N + ++ ++ + L+E Y F Sbjct: 23948 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE-RIKDKQFTIGGLLEATEYEF 24006 Query: 584 RVLSANRHGLSEPSEITSPIQAQDVTVVPSAPG--RVLASRNTKTSVVVQWD-----RPK 636 RV + N GLS P I+ + APG + + TK Q RP Sbjct: 24007 RVFAENETGLSRPRRTAMSIKTK--LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 24064 Query: 637 HEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY---IFRVKAVNAVGMS 693 D+ Y G L + +K R + T EQ ++ A N VG Sbjct: 24065 --PDIKWYRF-----GKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEV 24117 Query: 694 ENSQESDVIKVQAALTVPSHP--------YGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 E S K+ T HP YG H M +G VP + + Sbjct: 24118 ETSS-----KLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT-------W 24165 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 + ++ + + + ++ ++ + + ++K+ N+ G + Sbjct: 24166 FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI-----LDV 24220 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE-EDAGEWITVNQ 864 E P+ P + + S V+ WK P G S ++ Y V+ E ++ EW V+ Sbjct: 24221 EIQDKPDK-PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSS 24279 Query: 865 TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEA---RPG 912 + ++ +L + Y FRV A N G+ P + S V++++ +PG Sbjct: 24280 AISVTT-CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG 24329 Score = 121 bits (304), Expect = 4e-27 Identities = 113/424 (26%), Positives = 188/424 (44%), Gaps = 38/424 (8%) Query: 493 GEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVV 551 G+KE I L+ PGPP V EIS++ ++WEPP G P++ Y ++K Sbjct: 13276 GKKEYTIVVKVLD----TPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDA 13331 Query: 552 GSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVV 611 SW V + + S + V +L EGKSY FRV + N +G+ +P E ++A Sbjct: 13332 ERKSWSTVTTECSKTS--FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS----- 13384 Query: 612 PSAPGRVL---ASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGY 666 PG V+ +K+S + W +P + ++GY VD + N W+ K + Sbjct: 13385 -QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRV-MKSLSL 13441 Query: 667 NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK---VQAALTVPSHPYGITLLNCD 723 ++ LT G++Y FRV A N G S+ + V + V L + P + L + Sbjct: 13442 -QYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLP-DLCYLAKE 13499 Query: 724 GHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEF 783 + L K+P +P + + + + V SS T++ D + ++ Sbjct: 13500 NSNFRL--KIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKY 13556 Query: 784 KIAAVNLAGIGEPSDPSEHFKCEAWTMPEPG-PAYDLTFCEVRDTSLVMLWKAPVYSGSS 842 I N+AG E + + +PG P + F EV ++ + W P G S Sbjct: 13557 TITLKNVAGTKEGT-------ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGS 13609 Query: 843 PVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 ++ Y ++ R+ +W+T + +V+ L +G Y FRV A N GVG+ S Sbjct: 13610 EITNYILEKRDSVNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGE-GLKS 13667 Query: 903 EPVL 906 EP++ Sbjct: 13668 EPIV 13671 Score = 111 bits (278), Expect = 4e-24 Identities = 93/324 (28%), Positives = 134/324 (41%), Gaps = 41/324 (12%) Query: 152 RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRI-ESNYG 210 +AP LR+ V + + L V G P P+V+WY+ G I A+ KYRI E G Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKGG 24486 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 H L I DD Y ATN G VS A+ L + +P Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-----------------LEVEVPAKIH 24529 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 +P T LE G GE V++K PD P W + L+ + + Sbjct: 24530 LPKT------LEGMGAVHALRGEVVSIKIPFSGKPD-----PVITWQKGQDLIDNNGHYQ 24578 Query: 331 MFFGEGQASLSFSH-LHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDL 389 + SL F + + + D G Y + +R G+ + L V D P P + Sbjct: 24579 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADV-------PDPPRGV 24631 Query: 390 QCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFE 449 + D +RD V +TW P + S + Y V++C W++ A + +Y V LF Sbjct: 24632 KVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA--RETRYTVINLFG 24689 Query: 450 GRSYIFRVRAVNSAGISRPSRVSD 473 SY FRV A N G+S+PS S+ Sbjct: 24690 KTSYQFRVIAENKFGLSKPSEPSE 24713 Score = 95.5 bits (236), Expect = 3e-19 Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 25/408 (6%) Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCN 660 ++ QD P+ P ++ K S V+ W P + + Y V+ C A Sbjct: 24220 VEIQDKPDKPTGP--IVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24277 Query: 661 HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL 720 I + LT Y FRV A N G+S+ + S V+ +++ P P T+ Sbjct: 24278 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24337 Query: 721 NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL 780 S + WK P GG+ I YYL+KRE W V + + T+ +V L EG Sbjct: 24338 AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLE 24397 Query: 781 YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAY--DLTFCEVRDTSLVMLWKAPVY 838 YEF++ NL G E S+ SE ++ +P P + +L VR S L V Sbjct: 24398 YEFRVKCENLGGESEWSEISEPITPKS-DVPIQAPHFKEELRNLNVRYQSNATL-VCKVT 24455 Query: 839 SGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANG--- 894 P+ ++ +E A G + + L ++ + V++VRA N G Sbjct: 24456 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 24515 Query: 895 ------VGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYE 948 V P+ P +E G + A E +I + F + TW K + Sbjct: 24516 GTASLEVEVPAKIHLPKTLE---GMGAVHALRGEVVSIKIPFSGK---PDPVITWQKGQD 24569 Query: 949 EISDDERFKIETVGDHSKLYLKN-PDKEDLGTYSVSVSDTDGVSSSFV 995 I ++ +++ + L N +++D G Y V + G+ V Sbjct: 24570 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24617 Score = 77.8 bits (190), Expect = 7e-14 Identities = 113/534 (21%), Positives = 206/534 (38%), Gaps = 93/534 (17%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K+ EI E+FKI G +L + N ED Y+ V D Sbjct: 2855 FECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-VCGNDQ 2913 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 VS++ + P + ++ N + TI + + YE SY++ Sbjct: 2914 VSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYE------------------GISYKW 2955 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + N E+ ++ +++ K T + + F + T+ GKA S ++L + Sbjct: 2956 LKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYV---- 3007 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDV- 1168 E + EF + H + V E+ C+V+ + + +W+KDD Sbjct: 3008 --------EARHIEFRK----HIKDI---KVLEKKRAMFECEVS--EPDITVQWMKDDQE 3050 Query: 1169 LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAM 1227 L T+ + E+ + LLIP D G+Y G +VS ++ + D I ++ Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGRDVRIRSI 3106 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS--EHMRIGGSEEM 1285 + ++V+ E R + D++ +W +I+ E + + Sbjct: 3107 KK-------EVQVI---EKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRI 3156 Query: 1286 AWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGR 1345 + I E + D G+YTF G++ +L ++ + E Q Sbjct: 3157 HRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQELQP------------- 3201 Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVK-VEQAKYVSMT 1404 VT+ GK + G P P++ W+K +Q LS F K + + ++ Sbjct: 3202 --------VTVQSGKPARFCAVISGRPQPKISWYKEEQ--LLSTGFKCKFLHDGQEYTLL 3251 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPA 1458 + ED+ Y+ KN YG ++SV ++P++ P Q P PA Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSV-----EVPEVVSPDQEMPVYPPA 3300 Score = 65.9 bits (159), Expect = 3e-10 Identities = 67/248 (27%), Positives = 102/248 (41%), Gaps = 30/248 (12%) Query: 30 DEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRY 89 +EY K A ++SS S R + + L + + R E+ E + R Sbjct: 25752 EEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRS 25811 Query: 90 QSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEER 149 + E R R S ++ + L+R + + D ++ + M+ L ++ T E + Sbjct: 25812 PT-----PERTRPRSPSPVS---SERSLSRFERSARFDIFSRYESMKAALKTQK-TSERK 25862 Query: 150 ----------ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE 199 + AP I +R+RSH V + + VQ PT V+WY +G + E Sbjct: 25863 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG---VELQE 25919 Query: 200 PGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVV--------RRFRG 251 K + GV TLEI DD+ TY AV TN G+ S A + V R Sbjct: 25920 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR 25979 Query: 252 DEEPFRSV 259 DEE RSV Sbjct: 25980 DEEVPRSV 25987 Score = 65.9 bits (159), Expect = 3e-10 Identities = 50/166 (30%), Positives = 76/166 (45%), Gaps = 22/166 (13%) Query: 1262 VNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTF--EIFDGKDNHQRSLDLS 1319 V W ++++SE R G S L I + + +D+G T + +G Q L LS Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26630 Query: 1320 GQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWF 1379 + D A AF + R + I EG+ + TC + G P PE+ WF Sbjct: 26631 KELSD----------APAFISQPRSQ---------NINEGQNVLFTCEISGEPSPEIEWF 26671 Query: 1380 KNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 KN+ I +S + S+ + Y S+ I+ + DSGKY+I KN G Sbjct: 26672 KNNLPISISSNVSISRSRNVY-SLEIRNASVSDSGKYTIKAKNFRG 26716 Score = 63.9 bits (154), Expect = 1e-09 Identities = 61/247 (24%), Positives = 97/247 (39%), Gaps = 22/247 (8%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + +L++ + E +++ G P P + W K+ +I P K RIE G Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L+I+ D+A Y+A A N G+ +T V V + EP R + +P G + I Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAA 1628 Query: 274 THFDVQFLE------KFGVTFRREGETVTLKCTMLVTPDLKRVQPR-------------- 313 + L + G + +E + L + LKR P Sbjct: 1629 PELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTM 1688 Query: 314 -AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372 EW D L+ + +M G SL + + D G+ T R ++ G SA L V Sbjct: 1689 VVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748 Query: 373 RDADPLV 379 +D LV Sbjct: 1749 KDEKSLV 1755 Score = 62.0 bits (149), Expect = 4e-09 Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 123 RDKLDKYAIQQMMEDKLAWERHTFEERI-SRAPEILVRLRSHTVWERMSVKLCFTVQGFP 181 R+ D Y + M + K R T R+ R PE + L + T + +V+ T+ P Sbjct: 25165 REVYDYYCRRTMKKIK----RRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 25220 Query: 182 TPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTN 241 P V WYK G I KY ES+ G++ L IN DD A Y+ VA N +G+ S Sbjct: 25221 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 25280 Query: 242 AAVVV 246 A + V Sbjct: 25281 AKLTV 25285 Score = 61.6 bits (148), Expect = 5e-09 Identities = 73/333 (21%), Positives = 124/333 (37%), Gaps = 48/333 (14%) Query: 76 STQEDEEQENRSRYQSLVA--AYGEAKRQRFLS-ELAHLEEDVHLARSQARDKLDKYAIQ 132 ++Q +E+ RS + L AY + ++ E + +V ++ R+ L Y Sbjct: 25975 ASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHS 26034 Query: 133 QMMEDK-LAWERHTFEERISR-------APEILVRLRSHTVWERMSVKLCFTVQGFPTPV 184 E K A E + EE+ + A IL + RS TV+E S + G P P Sbjct: 26035 ASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT 26094 Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V W + G ++ +A ++++ + T EI+ D YS V N+ G+ + Sbjct: 26095 VTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL 26151 Query: 245 VVRRFRGDEEPFRS----------------------VGLPIGLPLSSMIP---------- 272 +++ R E+ S V P ++ P Sbjct: 26152 TIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEK 26211 Query: 273 YTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMF 332 H V K + E K T +V + R + WY+D LKE+ + Sbjct: 26212 VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK-EVTWYKDGKKLKENGHFQFH 26270 Query: 333 FG-EGQASLSFSHLHKDDEGLYTLRIVSRGGVS 364 + +G L ++L + D+G Y I GG S Sbjct: 26271 YSADGTYELKINNLTESDQGEYVCEISGEGGTS 26303 Score = 61.2 bits (147), Expect = 7e-09 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D+VTI G L L V G P+P++IW K D+++ L E S++ K + IK Sbjct: 22558 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY-TGKRATAVIKFCDRS 22616 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ +KN G + + V V V Sbjct: 22617 DSGKYTLTVKNASGTKAVSVMVKV 22640 Score = 59.3 bits (142), Expect = 3e-08 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 24/201 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P++L L+ TV + C + G P P + WYK+ L+ K + + +T Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF---KCKFLHDGQEYT 3249 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPY 273 L + A +D A Y+ A N +G +T+A++ SV +P + +P Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASL-------------SVEVPEVVSPDQEMPV 3296 Query: 274 THFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFF 333 + + T EG+ +C + T DLK WY D +K S++ +M Sbjct: 3297 --YPPAIITPLQDTVTSEGQPARFQCRVSGT-DLK-----VSWYSKDKKIKPSRFFRMTQ 3348 Query: 334 GEGQASLSFSHLHKDDEGLYT 354 E L + + +DEG YT Sbjct: 3349 FEDTYQLEIAEAYPEDEGTYT 3369 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/337 (21%), Positives = 124/337 (36%), Gaps = 49/337 (14%) Query: 1129 GPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW------LKDDVLYETETLPNLERGI 1182 GP + +H E V+ VCK+ N + T W L++ YE E G+ Sbjct: 25071 GPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEI----TYEDGV 25126 Query: 1183 CELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK----VYDDMILAMSRVCGKSASPL 1238 L + ++K D G Y+ + +D G+D S E+ K VYD + + + Sbjct: 25127 AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTM 25186 Query: 1239 KVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL---QICEPTE 1295 ++L P L + K + + + + + W Q +P + Sbjct: 25187 RLLERPPEFTLPLYNK---------TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKN-RGRLIGGLPDVV 1354 DK KYTFE D L ++ D+ AE+ + E + + +L L Sbjct: 25238 NDK-KYTFE----SDKGLYQLTINSVTTDDD-AEYTVVARNKYGEDSCKAKLTVTLHPPP 25291 Query: 1355 T----------------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA 1398 T EG+++ V G P P + W K+ Q + L + + E Sbjct: 25292 TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGL 25351 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 Y ++ I+ ED+G Y + N G + V Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388 Score = 58.9 bits (141), Expect = 3e-08 Identities = 104/506 (20%), Positives = 199/506 (39%), Gaps = 98/506 (19%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ T+ ++ W ++ E I D ++ I L +++ +D Y+VS+++ G Sbjct: 6162 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6221 Query: 990 VS----SSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDA 1045 + ++ +++ E+L + PLK E +K V FW + L+ Sbjct: 6222 ENVKSAANLIVEEEDLRIVE-----------PLKD---IETMEKKSVTFWCKVNRLN--V 6265 Query: 1046 SYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVL 1105 + ++ N EV + DK ++ + F +EG Y V G+ KS + L++ Sbjct: 6266 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFP--DEGEYIVTA--GQDKSVAELLI 6321 Query: 1106 IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKW-- 1163 I EA + E L Q VTE + C+++ K KW Sbjct: 6322 I---------EAPTEFVEHLEDQ----------TVTEFDDAVFSCQLSREKANV--KWYR 6360 Query: 1164 ----LKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219 +K+ Y+ E ++ R L+I D EY ++D + + A Sbjct: 6361 NGREIKEGKKYKFEKDGSIHR----LIIKDCRLDDECEYACGVEDRKSR-------ARLF 6409 Query: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279 +++ + + R P +L P G + + D+++V W + + + ++ Sbjct: 6410 VEEIPVEIIR------PPQDILEAP-GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQM 6462 Query: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 ++ LQIC+ +D+G+Y F D EA A+ + A Sbjct: 6463 MSEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIK 6506 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 ++ ++ DV GK L + P E WFK ++ + ++ EQ Sbjct: 6507 TADQDLVV----DV-----GKPLTMVVPYDAYPKAEAEWFKENEPLS-TKTIDTTAEQTS 6556 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + K D G+Y I ++NK+G Sbjct: 6557 FRILEAK---KGDKGRYKIVLQNKHG 6579 Score = 58.5 bits (140), Expect = 4e-08 Identities = 36/101 (35%), Positives = 61/101 (60%), Gaps = 6/101 (5%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + RL+S TV + V+L V G PTPVV++Y+DG+ I + + ++I +++ Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEE 254 L I A +D+ TYS ATN+ G+ ++ A ++V +G+EE Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV---QGEEE 198 Score = 58.2 bits (139), Expect = 6e-08 Identities = 112/571 (19%), Positives = 197/571 (34%), Gaps = 110/571 (19%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F+C+ W K +E+ +R KI+ +L + + D G Y+V Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVS 3090 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASY-- 1047 + FV + R+ ++ E+ ++ +K R + DA + Sbjct: 3091 TAKLFVEGRDV--RIRSIKKEV-------------QVIEKQRAVVEFEVNEDDVDAHWYK 3135 Query: 1048 -----RFIINDRE--VSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQ 1100 F + +R V + IHR M + + G YT +++ Sbjct: 3136 DGIEINFQVQERHKYVVERRIHR-----------MFISETRQSDAGEYTFVA----GRNR 3180 Query: 1101 SSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETV 1160 SS+ L +A + P + L + + C V + + + Sbjct: 3181 SSVTLYVNA-----------------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPK 3223 Query: 1161 FKWLKDDVLYETETLPNLERGICE--LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218 W K++ L T E LL+ + +D Y K+D G + ++ + Sbjct: 3224 ISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283 Query: 1219 VYDDMILAMSRVCGKSA--SPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSS 1274 V + + A +PL+ T EG R QC + ++KV+W KD KI S Sbjct: 3284 VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQC--RVSGTDLKVSWYSKDKKIKPS 3341 Query: 1275 EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFD---------E 1325 R+ E+ L+I E +D+G YTF + + +LS +A + E Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401 Query: 1326 AFAEFQQFKAAAFAEKNRG---------------RLIGGLPDVVT--------------- 1355 E ++F ++ + + G L+ P T Sbjct: 3402 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIK 3461 Query: 1356 ------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 I G L+ TV G P P++ WF N + S + + + S+ I Sbjct: 3462 EVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTK 3520 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGE 1440 ED G+Y+ N YG + + GE Sbjct: 3521 LEDEGEYTCMASNDYGKTICSAYLKINSKGE 3551 Score = 58.2 bits (139), Expect = 6e-08 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207 E IS P I+ L+ TV K G P P W KDG I Q GKY++ Sbjct: 26349 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG---GKYKLSE 26405 Query: 208 NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253 + G LEI++ D D+ Y+ N+ G VS++ + ++ + E Sbjct: 26406 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTE 26451 Score = 57.0 bits (136), Expect = 1e-07 Identities = 109/586 (18%), Positives = 215/586 (36%), Gaps = 97/586 (16%) Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEAR--------PGTKEISAGVDEQG 924 KV +GK + +R V G+ T++ A TK + E+G Sbjct: 5743 KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 5802 Query: 925 NIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 + +C+ + ++ W K+ EI ++++I G KL + + ED+ TY+ Sbjct: 5803 ATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPD 1044 D S + + P +E L L++ ++ +K RF + E + Sbjct: 5862 KDFK-TSCNLNVVPPHVEFLRPLTD--------------LQVREKEMARF--ECELSREN 5904 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 A ++ + E+ + + I A I +V+++ +++E Y+ ++ + Sbjct: 5905 AKVKWFKDGAEIKKGKKYDIISKGAVRI--LVINKCLLDDEAEYSCEVRTART------- 5955 Query: 1105 LIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWL 1164 TVLEE K + +V+E ++LVC+V+ E + W Sbjct: 5956 ---SGMLTVLEEEAVFTKNL-----------ANIEVSETDTIKLVCEVSKPGAEVI--WY 5999 Query: 1165 K-DDVLYETETLPNLERGICELL-IPKLSKKDHGEYKATLKDDRGQ-DVSILEIAGKVYD 1221 K D+ + ET L G +L I +D G Y L R V + E+A + Sbjct: 6000 KGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFI- 6058 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGG 1281 L++L EG + + + V W D + S + + Sbjct: 6059 -----------SKPQNLEIL---EGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIA 6104 Query: 1282 SEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK 1341 + L + + T +D G Y + + AA Sbjct: 6105 DGKKRVLVVKDATLQDMGTYVVMVGAAR------------------------AAAHLTVI 6140 Query: 1342 NRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV 1401 + R++ L D + E + + C V + WF+N++ I S + + + Y Sbjct: 6141 EKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY- 6197 Query: 1402 SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 ++ I+ +D Y++++ N + GE + ++ E + + P Sbjct: 6198 TLRIRDAHLDDQANYNVSLTN-HRGENVKSAANLIVEEEDLRIVEP 6242 Score = 56.2 bits (134), Expect = 2e-07 Identities = 98/501 (19%), Positives = 188/501 (37%), Gaps = 63/501 (12%) Query: 948 EEISD----DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 EEIS E K+ KL LK + L + V S + S V EE+ + Sbjct: 26473 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIV--HEEITK 26530 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 S E++ +K+ ++G+ R L+A +++ ++++N E+++SE +R Sbjct: 26531 TSQASEEVRTHA-EIKAFSTQMSINEGQ-RLVLKA-NIAGATDVKWVLNGVELTNSEEYR 26587 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 + + + E T + +G K Q L L KE Sbjct: 26588 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL---------------SKE 26632 Query: 1124 FLRKQGPHF-AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERG- 1181 P F ++ ++ E V C+++ + +W K+++ + ++ R Sbjct: 26633 L--SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEI-EWFKNNLPISISSNVSISRSR 26689 Query: 1182 -ICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKV 1240 + L I S D G+Y K+ RGQ + + M+L + + V Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL-------MVLPLVEEPSREV----V 26738 Query: 1241 LCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGK 1300 L T LQ + + ++++ ++A SS EM + + + Sbjct: 26739 LRTSGDTSLQG--SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM-- 26794 Query: 1301 YTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG-----RLIGGLPDVVT 1355 + +++S +F + Q +++ G I LP ++ Sbjct: 26795 -----------QESFVEMSSSSF-MGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDIS 26842 Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVTSEDSG 1414 I EGK L + C G P PEV W + I E +E ++ I V +D G Sbjct: 26843 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGG 26902 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 Y++++ N++G + V + + Sbjct: 26903 LYTLSLGNEFGSDSATVNIHI 26923 Score = 55.5 bits (132), Expect = 4e-07 Identities = 40/202 (19%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Query: 1247 IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIF 1306 ++ C ++ + +V W ++ +SE I + +A L + + T+ D G Y ++ Sbjct: 25088 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25147 Query: 1307 DGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEK-NRGRLIGGLPDVV------TIMEG 1359 + +L + E + + + + + RL+ P+ T G Sbjct: 25148 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25207 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEH---FSVKVEQAKYVSMTIKGVTSEDSGKY 1416 + + T+ +P+P V W+K+ Q I+ ++ ++ + ++ Y +TI VT++D +Y Sbjct: 25208 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEY 25266 Query: 1417 SINIKNKYGGEKIDVTVSVYKH 1438 ++ +NKYG + ++V H Sbjct: 25267 TVVARNKYGEDSCKAKLTVTLH 25288 Score = 55.5 bits (132), Expect = 4e-07 Identities = 69/264 (26%), Positives = 108/264 (40%), Gaps = 19/264 (7%) Query: 12 RHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLS-QRSSSQRASSQTSLGGTICRV 70 R S Q + L E ASK S + + S ++S ++TS R Sbjct: 26481 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRT 26540 Query: 71 CA--KRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEE--------DVHLARS 120 A K STQ + R ++ +A + K EL + EE D L Sbjct: 26541 HAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK 26600 Query: 121 QA--RDKLDKYAIQQMMEDKLAWERH-TFEERISRAPEILVRLRSHTVWERMSVKLCFTV 177 QA RD+ I + E + + T + +S AP + + RS + E +V + Sbjct: 26601 QASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI 26660 Query: 178 QGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQ 237 G P+P ++W+K+ I ++ I + V++LEI A D+ Y+ A N GQ Sbjct: 26661 SGEPSPEIEWFKNNLPISISS---NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ 26717 Query: 238 VSTNAAVVVRRFRGDEEPFRSVGL 261 S A+++V EEP R V L Sbjct: 26718 CSATASLMVLPL--VEEPSREVVL 26739 Score = 55.1 bits (131), Expect = 5e-07 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 +P+ +TI GK L + V+G P P W K + ++ S H +V + + + IK VT Sbjct: 12407 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVT 12465 Query: 1410 SEDSGKYSINIKNKYG--GEKIDVTV 1433 +DSG YS+ +N G +KI V V Sbjct: 12466 RKDSGYYSLTAENSSGTDTQKIKVVV 12491 Score = 54.7 bits (130), Expect = 6e-07 Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 29/243 (11%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P ++ L++ TV E SV L + G+P+P V WY++ I + + ++I G+ Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIAR 953 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVVR--------------RFRGDEEPFRS- 258 L I A +D+ ++ A N G VST+ + V+ +F +E+ F Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013 Query: 259 ---VGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAE 315 V L P F+ K V EG +V C + P +P Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVY 1068 Query: 316 WYRDDVLLKESKWTKMFFGE--GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 W + V L K+ + + G+ L S DD G YT+ + ++ G + SA L + Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LE 1127 Query: 374 DAD 376 +AD Sbjct: 1128 EAD 1130 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L+ GL +V T++EG+++ L C + G P P V W++ D I+ S F + Q+ + I Sbjct: 899 LVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMI 956 Query: 1406 KGVTSEDSGKYSINIKNKYG 1425 + +EDSG+++ + N+ G Sbjct: 957 REAFAEDSGRFTCSAVNEAG 976 Score = 52.0 bits (123), Expect = 4e-06 Identities = 51/223 (22%), Positives = 91/223 (40%), Gaps = 31/223 (13%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 ++AP L+S V E + + GFP P V W++DG +I + PG +I + G Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPG-VQISFSDG 61 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSM 270 L I ++ YS ATN GQ ++ A ++V + + P Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV---KAETAP--------------- 103 Query: 271 IPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 F+++ R+G V L+ + P P ++YRD ++ S + Sbjct: 104 -------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLDFQ 151 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 + SL + + +D G Y++ + G + +A L V+ Sbjct: 152 ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 52.0 bits (123), Expect = 4e-06 Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 27/207 (13%) Query: 1245 EGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFE 1304 E + L+C + + V W +D +I SS +I +A L I E +D G++T Sbjct: 912 ESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 970 Query: 1305 IFDGKDNHQRSLDLSGQAFDE-----------------AFAEFQQ--FKAAAFAEKNRGR 1345 + S L+ Q +E F E + + E+ G Sbjct: 971 AVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGP 1030 Query: 1346 LIGGLPDVVT------IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKV-EQA 1398 P +T ++EG ++ C V GNP P V W K+ + + V +Q Sbjct: 1031 GEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090 Query: 1399 KYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + I ++D+G+Y+I ++NK+G Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHG 1117 Score = 50.8 bits (120), Expect = 9e-06 Identities = 113/619 (18%), Positives = 230/619 (37%), Gaps = 109/619 (17%) Query: 872 LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP---GTKEISAGVDEQGNIYL 928 L + D+ + V+A+N G + + +LV+A+ T+E+ V ++ + Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAG---ETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146 Query: 929 GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988 F+C+ + W K E+ + +++++ + L + D D YS + + + Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE 2206 Query: 989 GVSSS-----------FVLDPEELERLMALSNEIK-------------NPTIPLKSELAY 1024 V ++ FV + +++E + S E++ + + LKS Y Sbjct: 2207 NVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKY 2266 Query: 1025 EIFDK-GRVRFWLQAEHLSPDASYRFIIN----------------------DREVSDSEI 1061 I + GR ++ Y F+I+ D++V + +I Sbjct: 2267 TITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDI 2326 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +++ + +E V + E + + V I K QS ++LI D K F Sbjct: 2327 VQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK---QSHMLLIEDMTKEDAGNYSFTI 2383 Query: 1122 KEFLRKQGPHFAEYL--------HWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE 1173 + Y +V E + L CKV+ +V +L D+ + + Sbjct: 2384 PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDD 2443 Query: 1174 TLPNLERGICE-LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCG 1232 + + +G + L+I + D G YK I G+V + L++ ++ Sbjct: 2444 RVQAIVKGTKQRLVINRTHASDEGPYKL--------------IVGRVETNCNLSVEKI-- 2487 Query: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 K L+ L E + ++ + V W KD +I S +I ++ L + Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLN 2547 Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352 + D+GKYTF + G++ L ++G A + + Sbjct: 2548 MMKDDEGKYTF--YAGENMTSGKLTVAGGAISKPLTD----------------------- 2582 Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 T+ E + C V NPD + W ++ + + L+ + + + K + I +D Sbjct: 2583 -QTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKR-RLIIAATKLDD 2639 Query: 1413 SGKYSINIKNKYGGEKIDV 1431 G+Y+ + K+ V Sbjct: 2640 IGEYTYKVATSKTSAKLKV 2658 Score = 50.1 bits (118), Expect = 2e-05 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 6/107 (5%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P +T+ EG++ +C G P P V W + Q + S V + K + I V + Sbjct: 26070 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQA 26128 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA---PPQQAKPK 1454 D G YS+ ++N G ++ + T+++ K ++ + A PP+ P+ Sbjct: 26129 SDEGNYSVVVENSEGKQEAEFTLTIQK--ARVTEKAVTSPPRVKSPE 26173 Score = 48.9 bits (115), Expect = 4e-05 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P+ V ++EG+T C V G P P+V W+ N Q I+ S+ F V+ + Y + I S Sbjct: 1801 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY--LDIVDCKS 1858 Query: 1411 EDSGKYSINIKNKYG 1425 D+G+ + +N G Sbjct: 1859 YDTGEVKVTAENPEG 1873 Score = 48.5 bits (114), Expect = 5e-05 Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 26/207 (12%) Query: 1261 KVNWCHKDAKISSSE--HMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDL 1318 +V+W IS+S ++I S+ A L I T+ + G+Y+ + +G Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNG---------- 85 Query: 1319 SGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIW 1378 SGQA A + AE + L + T+ +G + L V G P P V + Sbjct: 86 SGQATSTA-------ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKF 137 Query: 1379 FKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKH 1438 +++ +IQ S F + E Y S+ I EDSG YS+N N G + T + Sbjct: 138 YRDGAEIQSSLDFQISQEGDLY-SLLIAEAYPEDSGTYSVNATNSVG--RATSTAELLVQ 194 Query: 1439 GEKIPDMAPPQQAKPKLIPASASAAGQ 1465 GE + P ++ K + A S + Q Sbjct: 195 GE---EEVPAKKTKTIVSTAQISESRQ 218 Score = 48.5 bits (114), Expect = 5e-05 Identities = 124/606 (20%), Positives = 230/606 (37%), Gaps = 106/606 (17%) Query: 832 LWKAPVYSGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 L+ V+ G + + + ++ E D G+W Q TA+ ++ ++ GK ++ + Sbjct: 5260 LYGVEVFVGET--AHFEIELSEPDVHGQWKLKGQPLTASPDCEI--IEDGKKHILILHNC 5315 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEIS-------AGVDEQGNIYLGFDCQEMTDASQFTW 943 G+ S + A KE+ + V F+C+ + F W Sbjct: 5316 QLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRW 5375 Query: 944 CKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELER 1003 K +EI+ D+RF++ G + +K+ ED Y D S +++ L+ Sbjct: 5376 LKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH-TSGKLIIEGIRLKF 5434 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHR 1063 L PLK A E K F ++ H + ++ ND+ + + Sbjct: 5435 L-----------TPLKDVTAKE---KESAVFTVELSH--DNIRVKWFKNDQRLHTTRSVS 5478 Query: 1064 IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKE 1123 ++ + T I SI++ V+ ++ + +A TVLE Sbjct: 5479 MQDEGKTHSI--TFKDLSIDDTSQIRVE----------AMGMSSEAKLTVLE-------- 5518 Query: 1124 FLRKQGPHFAEYLH-WDVTEECEVRLVCKVANTKKETVFKWLKD--DVLYETETLPNLER 1180 P+F L + E+ EV L C++ +K + KW KD ++ + + Sbjct: 5519 ----GDPYFTGKLQDYTGVEKDEVILQCEI--SKADAPVKWFKDGKEIKPSKNAVIKADG 5572 Query: 1181 GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV-YDDMILAMSRVCGKSASPLK 1239 L++ K K D G+Y D G D + +GK+ +D + + R PL Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTD----KTSGKLDIEDREIKLVR-------PLH 5617 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 + E + + D++ NW K A LQ + K++G Sbjct: 5618 SVEVMETETARFETEISEDDIHANWKLKGE----------------ALLQTPDCEIKEEG 5661 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE-KNRGRLIGGLPDV--VTI 1356 K + H LD +G +FQ + A + + R+IG L + VT+ Sbjct: 5662 KIHSLVL-----HNCRLDQTGG------VDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5710 Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 G+T C + D V W+ + ++ S+ V + K ++T++ V ED+G+ Sbjct: 5711 TAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKV-VPRSEGKVHTLTLRDVKLEDAGEV 5768 Query: 1417 SINIKN 1422 + K+ Sbjct: 5769 QLTAKD 5774 Score = 48.5 bits (114), Expect = 5e-05 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D +TI G+ LT G P P+V WFK++ D+ + +K A IK S Sbjct: 10329 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRS- 10387 Query: 1412 DSGKYSINIKNKYGGEK 1428 DSGKY + ++N G K Sbjct: 10388 DSGKYCVVVENSTGSRK 10404 Score = 48.5 bits (114), Expect = 5e-05 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G++ + ++G P P + W K DQ++ + +K S+++K Sbjct: 16054 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFA-TSLSVKDAVRV 16112 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y + KN G + V V V Sbjct: 16113 DSGNYILKAKNVAGERSVTVNVKV 16136 Score = 48.5 bits (114), Expect = 5e-05 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 15/145 (10%) Query: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQA-FDEAFAEFQQFKAAAFAEKNRGRLIGGLP 1351 P K KY+F + ++++ G + + E+ AE + + + L L Sbjct: 22908 PDLKMGQKYSFRV--------AAVNVKGMSEYSESIAEIEPVERIEIPDLE---LADDLK 22956 Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 VTI G +L L +V G P P + W K Q I L+ + ++ Y + + V Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTES-YSLLIVDKVNRY 23013 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSVY 1436 D+GKY+I +N+ G + V V VY Sbjct: 23014 DAGKYTIEAENQSGKKSATVLVKVY 23038 Score = 48.1 bits (113), Expect = 6e-05 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V I EG L + GNP+P+++W KN I ++ +++E K ++ I S+D Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIP 1457 S Y+ NK G + V+V + A P+ + +IP Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVE------VEFAEPEPERKLIIP 1617 Score = 48.1 bits (113), Expect = 6e-05 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L ++ I G +L L + G P PEV W K D +I+ + V + + S+ + V Sbjct: 16451 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT---SSFTSLVLDNVN 16507 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSGKY++ ++N G + VTV V Sbjct: 16508 RYDSGKYTLTLENSSGTKSAFVTVRV 16533 Score = 47.4 bits (111), Expect = 1e-04 Identities = 91/436 (20%), Positives = 177/436 (40%), Gaps = 67/436 (15%) Query: 999 EELERLMALSNEIKNPTI-PLKSEL-----AYEIFDKGRVRFWLQAEHLSPDASYRFIIN 1052 EE ++ +A +I PT P K EL A +IF+ R Q DA +R + Sbjct: 2001 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFE----RIQSQTVGQGSDAHFRVRVV 2056 Query: 1053 DREVSDSEIHR--IKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAF 1110 + + E ++ +K +++ I + + + I D A+ +S+++ Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIY------WYWPEDNVCELVIRDVTAEDSASIMV----- 2105 Query: 1111 KTVLEEAEFQRKEFLRKQGPH---FAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDD 1167 K + E FL Q F + L V +E + + ++ KW KD Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165 Query: 1168 V-LYETETLP-NLERGICELLIPKLSKKDHGEYKATLKDDRG-QDVSILEIAGKVYDDMI 1224 + ++E + + +R + L I + D +Y L +D + + L + G V + + Sbjct: 2166 MEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV- 2224 Query: 1225 LAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEE 1284 K ++V + G L+C + + ++ W H D ++ S+ I Sbjct: 2225 --------KELQDIEVPESYSG-ELECIVS--PENIEGKWYHNDVELKSNGKYTITSRRG 2273 Query: 1285 MAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRG 1344 L + + T++D+G+Y+F + DGK + + K A Sbjct: 2274 RQNLTVKDVTKEDQGEYSF-VIDGKKTTCK----------------LKMKPRPIA----- 2311 Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 ++ GL D + EG + L V E +W K+ Q++Q S+ + +++ ++ + Sbjct: 2312 -ILQGLSD-QKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHM-LL 2367 Query: 1405 IKGVTSEDSGKYSINI 1420 I+ +T ED+G YS I Sbjct: 2368 IEDMTKEDAGNYSFTI 2383 Score = 47.0 bits (110), Expect = 1e-04 Identities = 116/553 (20%), Positives = 198/553 (35%), Gaps = 103/553 (18%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS--VSVSDT 987 F+C + TW K I + + + G KL++ + D G Y+ + + + Sbjct: 4641 FECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4700 Query: 988 DGVSSSFVLDPEELERLMALSNE----IKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSP 1043 + S++ ++ E R + E +K + L EL +K R W + + Sbjct: 4701 EKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL-----NKERDVVWRKDGKIVV 4755 Query: 1044 DASYRFI-----------INDREVSDS--------EIHRIKCDKATGIIEMVMDRFSIEN 1084 + R + IND + +D+ + ++C ++E++ D Sbjct: 4756 EKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL---- 4811 Query: 1085 EGTYTVQIHDGKAKSQSSLVLIGDAFKTVLE----------EAEFQRKEFLRKQGPHF-- 1132 I D K + + + D K AE K + + G H Sbjct: 4812 ----VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYL 4867 Query: 1133 --AEYLHWDVTE---ECE-VRLVCKVANTKKET-VFKWLKDDVLYETET----------- 1174 + D+ E E E R K+ ++E + K ++D +YE E+ Sbjct: 4868 KIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD 4927 Query: 1175 LPNLERGICELLIPKLS---KKDHGEYKATL-KDDRGQDVSILEIAGKVYDDMILAMSRV 1230 +P + ELL P + K + G+ TL K Q +L A IL + + Sbjct: 4928 IPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEI 4987 Query: 1231 CGKSASPLKVLCTPEG--IRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWL 1288 A PLK + PE R +C + T E V W I SS+ I + L Sbjct: 4988 ELDFAVPLKDVTVPERRQARFECVL---TREANVIWSKGPDIIKSSDKFDIIADGKKHIL 5044 Query: 1289 QICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIG 1348 I + D+G YT E+ E ++ A F R + + Sbjct: 5045 VINDSQFDDEGVYTAEV-----------------------EGKKTSARLFVTGIRLKFMS 5081 Query: 1349 GLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 L D T+ EG+T C + + V+WFKND + S + E K + +K V Sbjct: 5082 PLEDQ-TVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSE-GKTHKLEMKEV 5138 Query: 1409 TSEDSGKYSINIK 1421 T +D + +K Sbjct: 5139 TLDDISQIKAQVK 5151 Score = 47.0 bits (110), Expect = 1e-04 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+T+ G+T+ + V G P+P++ W K + + + + ++ V + IK Sbjct: 11419 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRA 11477 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY I+ KN G + V+V Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNV 11501 Score = 47.0 bits (110), Expect = 1e-04 Identities = 48/209 (22%), Positives = 81/209 (38%), Gaps = 22/209 (10%) Query: 1238 LKVLCTPEGIRLQCFMKYFTDEMK-VNWCHKDAKISSSEHMRIGGSEEMAW-LQICEPTE 1295 LK + E +L C ++ K V W K+ + H + S + + L+I TE Sbjct: 26227 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26286 Query: 1296 KDKGKYTFEIFDGKDNHQRSLDLSGQAF----------DEAFAEFQQFKAAAFAEKNRGR 1345 D+G+Y EI + +L GQAF E Q+ + K + Sbjct: 26287 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26346 Query: 1346 L---IGGLPDVVTIMEGKTLN------LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE 1396 I P +VT ++ T++ G P P IW K+ + I + + + Sbjct: 26347 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSED 26406 Query: 1397 QAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 + + + I + DSG Y+ +KN G Sbjct: 26407 KGGFF-LEIHKTDTSDSGLYTCTVKNSAG 26434 Score = 46.2 bits (108), Expect = 2e-04 Identities = 66/257 (25%), Positives = 98/257 (38%), Gaps = 51/257 (19%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKY-RIESNYGVH 212 P I+ L+ E + V G V + KD + +P ++ R+ + Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI-----KPSRFFRMTQFEDTY 3353 Query: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRR------------------------ 248 LEI A +D TY+ VA+NA GQVS+ A + + Sbjct: 3354 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSF 3413 Query: 249 FRGDEEPFRSVGLPIG-----LPLSSMIPY--THFDVQFLEKFGVTFRRE--------GE 293 +EE S L + L L S P T FD + E G F +E G+ Sbjct: 3414 LSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSE-KEGTGPIFIKEVSNADISMGD 3472 Query: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLY 353 TL T++ P +P+ +W+ + VLL S K F SL +DEG Y Sbjct: 3473 VATLSVTVIGIP-----KPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEY 3527 Query: 354 TLRIVSRGGVSDHSAFL 370 T + G + SA+L Sbjct: 3528 TCMASNDYGKTICSAYL 3544 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 +LI GL + G T+ + G P P W + +I+ EH++V+ + V +T Sbjct: 11018 KLIEGL----VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LT 11072 Query: 1405 IKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 IK D+G+Y I + N G + + V ++V Sbjct: 11073 IKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103 Score = 45.8 bits (107), Expect = 3e-04 Identities = 24/79 (30%), Positives = 39/79 (49%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY 1416 +EG+T V G P PE WF + Q I V +++ S+ I T DSG++ Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482 Query: 1417 SINIKNKYGGEKIDVTVSV 1435 ++ +N+ G I V ++V Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501 Score = 45.8 bits (107), Expect = 3e-04 Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 37/177 (20%) Query: 181 PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST 240 P V+WYKDG + E KYR+ S+ VH L I D D YS V V T Sbjct: 2155 PFVKVKWYKDGM---EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKT 2210 Query: 241 NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT 300 A ++V +++ + V+ L+ V GE L+C Sbjct: 2211 TAKLIVE--------------------GAVVEF----VKELQDIEVPESYSGE---LEC- 2242 Query: 301 MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRI 357 +V+P+ +WY +DV LK + + G+ +L+ + K+D+G Y+ I Sbjct: 2243 -IVSPE----NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI 2294 Score = 45.8 bits (107), Expect = 3e-04 Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 25/202 (12%) Query: 1257 TDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEP-TEKDKGKYTFEIFDGKDNHQRS 1315 T+ +VNW ++ + S E + + L I + TE +G+Y E + Sbjct: 4267 TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCE----------A 4316 Query: 1316 LDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375 L+ SG+ A + K AA K + + + + G TC + P+ Sbjct: 4317 LNDSGKTATSA--KLTVVKRAAPVIKRK-------IEPLEVALGHLAKFTCEIQSAPNVR 4367 Query: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 WFK ++I S+ S++ +KY+ S+ I D G+Y+ N+YG T++ Sbjct: 4368 FQWFKAGREIYESDKCSIR--SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 4425 Query: 1435 VYKHG--EKIPDMAPPQQAKPK 1454 V G +K+ + P ++ +PK Sbjct: 4426 VTVPGGEKKVRKLLPERKPEPK 4447 Score = 45.8 bits (107), Expect = 3e-04 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VV + TL L T+ G P+PEV W K + L++ ++V + + + I VT Sbjct: 18616 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEG--ILTDRAQIEV-TSSFTMLVIDNVT 18672 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 DSG+Y++ ++N G + V V V Sbjct: 18673 RFDSGRYNLTLENNSGSKTAFVNVRV 18698 Score = 45.4 bits (106), Expect = 4e-04 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 I G TL L+ + G P P+V W K D+D V +K + I+ ED G Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10789 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 YS+ ++N G + + V V V Sbjct: 10790 YSLTVENPAGSKTVSVKVLV 10809 Score = 45.1 bits (105), Expect = 5e-04 Identities = 91/479 (18%), Positives = 176/479 (36%), Gaps = 75/479 (15%) Query: 943 WCKSYEEISDDERFKIETVGDH-SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEEL 1001 W K+ +I +R D+ +L +++ ED + V + G +SS + Sbjct: 2065 WYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Query: 1002 ERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEI 1061 ++L+ + E+++ K +A + E P ++ + EV + + Sbjct: 2125 KQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGMEVHEGDK 2173 Query: 1062 HRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQR 1121 +R+ D+ + ++ S + E V + D K+ + L++ G + V E + + Sbjct: 2174 YRMHSDRKVHFLSILTIDTS-DAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIE- 2231 Query: 1122 KEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--E 1179 V E L C V+ E KW +DV ++ + Sbjct: 2232 ------------------VPESYSGELECIVSPENIEG--KWYHNDVELKSNGKYTITSR 2271 Query: 1180 RGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLK 1239 RG L + ++K+D GEY + D + + + L+ +VC Sbjct: 2272 RGRQNLTVKDVTKEDQGEYSFVI-DGKKTTCKLKMKPRPIAILQGLSDQKVC-------- 2322 Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKG 1299 EG +Q +K + ++ W ++ S+ + I ++ L I + T++D G Sbjct: 2323 -----EGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAG 2377 Query: 1300 KYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEG 1359 Y+F I +L LS ++ +I L D V ++EG Sbjct: 2378 NYSFTI--------PALGLSTSGRVSVYSV---------------DVITPLKD-VNVIEG 2413 Query: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 L C V V W+ ND+ I+ + V+ K + I + D G Y + Sbjct: 2414 TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ-RLVINRTHASDEGPYKL 2471 Score = 45.1 bits (105), Expect = 5e-04 Identities = 21/84 (25%), Positives = 42/84 (50%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+T L + G P P+V+W K+ ++++ + + ++ +K Sbjct: 18218 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18277 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + + N G + I +TV V Sbjct: 18278 DGGQYILKLSNVGGTKSIPITVKV 18301 Score = 44.7 bits (104), Expect = 7e-04 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK-YVSMTIKGVTSED 1412 V ++EG T + G P PEV WF++ Q I S V++ + +TI VT + Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74 Query: 1413 SGKYSINIKNKYG 1425 SG+YS+ N G Sbjct: 75 SGRYSLKATNGSG 87 Score = 44.7 bits (104), Expect = 7e-04 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + I G++L + V G P P V WFK+ +I+ + + + S+ ++ T + Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRD 21527 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 G Y++ KN G K ++ V V Sbjct: 21528 HRGVYTVEAKNASGSAKAEIKVKV 21551 Score = 44.3 bits (103), Expect = 9e-04 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D + + G+T L V G P P + W + D++I+ S +K K + + +K Sbjct: 17136 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL-LIVKDAIRI 17194 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D G+Y + N G + V V V Sbjct: 17195 DGGQYILRASNVAGSKSFPVNVKV 17218 Score = 43.9 bits (102), Expect = 0.001 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 E SV V G P P ++W KDG + + P I + L I +DT Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25368 Query: 227 YSAVATNAHGQVSTNAAVVVRRFRGDEEPFRS 258 Y ATN G S A + V R R ++ F+S Sbjct: 25369 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKS 25400 Score = 43.5 bits (101), Expect = 0.001 Identities = 60/266 (22%), Positives = 105/266 (39%), Gaps = 54/266 (20%) Query: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238 G PT VV+W DG + A + R+ + +G +L+ A D+ + ATN +G Sbjct: 1684 GDPTMVVEWLHDGKPLEAA---NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTD 1740 Query: 239 STNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKF----------GVTF 288 T+A ++V+ DE+ L S +P +Q +E+ GVT Sbjct: 1741 HTSATLIVK----DEK---------SLVEESQLPEGRKGLQRIEELERMAHEGALTGVTT 1787 Query: 289 RR------------------EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTK 330 + EGET +C + P QP+ WY + L+++SK + Sbjct: 1788 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFR 1842 Query: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR---DADPLVTGAPGAPM 387 + + +G L D G + + GV +H L ++ D ++ AP Sbjct: 1843 VRY-DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1901 Query: 388 DLQCHDANR-DYVIVTWKPPNTTTES 412 + H+ + + + P TTE+ Sbjct: 1902 EFHVHEPGKLQFEVQKVDRPVDTTET 1927 Score = 43.5 bits (101), Expect = 0.001 Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 8/141 (5%) Query: 107 ELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVW 166 EL H +++ +A + K I DK+ AP+I R++S TV Sbjct: 1991 ELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSM------EAPKIFERIQSQTVG 2044 Query: 167 ERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTAT 226 + V G P P +WYK+G I ++ Y E N V L I +D+A+ Sbjct: 2045 QGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN--VCELVIRDVTAEDSAS 2102 Query: 227 YSAVATNAHGQVSTNAAVVVR 247 A N G+ S++A ++V+ Sbjct: 2103 IMVKAINIAGETSSHAFLLVQ 2123 Score = 43.5 bits (101), Expect = 0.001 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G + +T G P P V+W K D D++ + + S+TI+ DSGK Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRT---SLTIENANRNDSGK 19757 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ I+N + + V V Sbjct: 19758 YTLTIQNVLSAASLTLVVKV 19777 Score = 43.1 bits (100), Expect = 0.002 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKM-FFGEGQASLSFSHLHKDD 349 EG VT C M P P+ WY+D +K + +M F +G+ASL + +D Sbjct: 1258 EGMGVTFHCKMSGYP-----LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312 Query: 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAP 383 EG+YT + G + S L+V A PL GAP Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYVEPAAPL--GAP 1344 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%) Query: 145 TFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR 204 T +++ + P+I++ V E + + V G+P P V WY +G LI ++ ++R Sbjct: 1786 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK---RFR 1842 Query: 205 IESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSV 259 + + G+H L+I DT A N G + + +++ E FRSV Sbjct: 1843 VRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ----REDFRSV 1892 Score = 43.1 bits (100), Expect = 0.002 Identities = 80/376 (21%), Positives = 138/376 (36%), Gaps = 82/376 (21%) Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 VL E TK + A ++ + C+ ++ W K EEI + R++I T G Sbjct: 5961 VLEEEAVFTKNL-ANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6019 Query: 965 SKLYLKNPDKEDLGTYSVSV--SDTDG------VSSSFVLDPEELERLMALSNE----IK 1012 L ++N ED G Y+ + S TDG +++ F+ P+ LE L E I Sbjct: 6020 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 6079 Query: 1013 NPTIP---------LKSELAYEIFDKGRVRFWL--------------------QAEHLSP 1043 + P L+S Y++ G+ R + A HL+ Sbjct: 6080 KESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV 6139 Query: 1044 DASYRFII--NDREVSDSEIHRIKCDKATGII--------EMVMDR---FSIENEGTYTV 1090 R ++ D V + + C+ T E + D ++ + YT+ Sbjct: 6140 IEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTL 6199 Query: 1091 QIHDGKAKSQSSLVL---------IGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVT 1141 +I D Q++ + + A ++EE + + E L+ + Sbjct: 6200 RIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLK----------DIETM 6249 Query: 1142 EECEVRLVCKVANTKKETVFKWLK--DDVLYETETLPNLERGICELLIPKLSKKDHGEYK 1199 E+ V CKV + KW K ++V ++ +++ L I D GEY Sbjct: 6250 EKKSVTFWCKV--NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI 6307 Query: 1200 ATLKDDRGQDVSILEI 1215 T GQD S+ E+ Sbjct: 6308 VT----AGQDKSVAEL 6319 Score = 43.1 bits (100), Expect = 0.002 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 + G ++ L G P P +W K D ++ L + ++T++ D+GK Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 21928 Query: 1416 YSINIKNKYGGEKIDVTVSV 1435 Y++ ++N G + I TV V Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVE-QAKYVSMTIKGV 1408 L V+T+ G T+ L V G P PEV W K+ L+ VK++ +A ++ Sbjct: 11710 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11769 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D GKY + N G TV+V Sbjct: 11770 KRSDGGKYVVTATNTAGSFVAYATVNV 11796 Score = 42.7 bits (99), Expect = 0.003 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + ++T+ G + L TVFG P P V W K+ ++ +E + + Q ++ + V Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVN 12862 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSV 1435 +DSG Y+I +N G + + + V Sbjct: 12863 RKDSGDYTITAENSSGSKSATIKLKV 12888 Score = 42.7 bits (99), Expect = 0.003 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 V + G+ +++ G PDP + W K I + H+ V V ++ + GV +D+ Sbjct: 24540 VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDA 24599 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 G Y + KN++G ++ V + V +PD PP+ K Sbjct: 24600 GFYVVCAKNRFGIDQKTVELDV----ADVPD--PPRGVK 24632 Score = 42.4 bits (98), Expect = 0.003 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 DV+ + G+ L + + G P P + W K+ +I+ + + + +T+K Sbjct: 19300 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRR 19358 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 D+G+Y + +KN G + V V Sbjct: 19359 DTGQYVLTLKNVAGTRSVAVNCKV 19382 Score = 42.0 bits (97), Expect = 0.004 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKN----DQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 + IM GKTL + V G P P +W K D+D + ++ K E + IK Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8670 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 +D G+Y I N G + V V+ + D+ P Sbjct: 8671 RKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKP 8708 Score = 42.0 bits (97), Expect = 0.004 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 1350 LPDVVTIMEGKTLNLTC-TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 + D +TI G T+ L ++ G P P+ W K +DI+ S+ + + +TIK Sbjct: 13887 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYA 13945 Query: 1409 TSEDSGKYSINIKNKYGGEKIDVTVSV 1435 T +D+G+Y+I N +G + V V+V Sbjct: 13946 TRKDAGEYTITATNPFGTKVEHVKVTV 13972 Score = 42.0 bits (97), Expect = 0.004 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G+ + L + G P P WF ++ SE +V+ K +TI+ T D+ Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH-TKVAKLTIRETTIRDT 23309 Query: 1414 GKYSINIKNKYG 1425 G+Y++ +KN G Sbjct: 23310 GEYTLELKNVTG 23321 Score = 41.6 bits (96), Expect = 0.006 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Query: 1349 GLPDVVTIM-EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 GLPD+ + E L + G P P V W K + + SV+ A ++ + Sbjct: 13489 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYD 13547 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+GKY+I +KN G ++ +++ V Sbjct: 13548 CQKSDAGKYTITLKNVAGTKEGTISIKV 13575 Score = 41.6 bits (96), Expect = 0.006 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVT 1409 L VVTI TL L + G P PEV W ++ + + S++ + Y + + V Sbjct: 15369 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHG--ESLDKASIE-STSSYTLLIVGNVN 15425 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 DSGKY + ++N G + V V V + PPQ K K Sbjct: 15426 RFDSGKYILTVENSSGSKSAFVNVRV------LDTPGPPQDLKVK 15464 Score = 41.6 bits (96), Expect = 0.006 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 +VV G ++ L + G P P + W+K+D+++Q + V+ S+ IK Sbjct: 20383 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20441 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 +SG Y + ++N G + V + Sbjct: 20442 NSGCYELKLRNAMGSASATIRVQI 20465 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 1346 LIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTI 1405 L G ++T G + + G P P+V W + ++ ++ S+ + + ++T+ Sbjct: 22152 LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDR-TTLTV 22210 Query: 1406 KGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 K DSG+Y + ++N G + VTV V Sbjct: 22211 KDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240 Score = 40.8 bits (94), Expect = 0.010 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%) Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 W+ EP + K + T + +GK R L+ Q + ++ +A E L Sbjct: 7137 WVACGEPVAETKMEVT-GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7195 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIK 1406 L +T+ G + L TV G P+P++ W K D ++ + +++ K ++TI Sbjct: 7196 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIV 7254 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 D+G Y I N G V V+V Sbjct: 7255 DSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283 Score = 40.4 bits (93), Expect = 0.013 Identities = 68/297 (22%), Positives = 116/297 (39%), Gaps = 49/297 (16%) Query: 1150 CKVANTKKETVFKWLKDDVL----YETETLPNLERGICELLIPKLSKKDHGEYKATLKDD 1205 C+V K V+ W K V Y + N + G C+L+I D GEY +++ Sbjct: 1057 CQVGGNPKPHVY-WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNK 1115 Query: 1206 RGQ---DVSILEIAG-----KVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFT 1257 G+ S+LE A K +M L ++V P KV T G + K + Sbjct: 1116 HGETSASASLLEEADYELLMKSQQEM-LYQTQVTAFVQEP-KVGETAPGFVYSEYEKEYE 1173 Query: 1258 DEMKV--NWCHKDAKISSS----EHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDN 1311 E + KD + + + I EE ++ + E K T E +D Sbjct: 1174 KEQALIRKKMAKDTVVVRTYVEDQEFHISSFEE----RLIKEIEYRIIKTTLEELLEEDG 1229 Query: 1312 HQR-SLDLS-GQAFDEAF-AEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTV 1368 ++ ++D+S +A + F + + ++ I+EG + C + Sbjct: 1230 EEKMAVDISESEAVESGFDSRIKNYR---------------------ILEGMGVTFHCKM 1268 Query: 1369 FGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 G P P++ W+K+ + I+ E + + Q S+ I V ED G Y+ N G Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325 Score = 40.4 bits (93), Expect = 0.013 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 11/109 (10%) Query: 159 RLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE-SNYGVHTLEIN 217 R++++ + E M V + G+P P + WYKDG I +Y+++ G +L I Sbjct: 1250 RIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE---RYQMDFLQDGRASLRIP 1306 Query: 218 RADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +D Y+A A+N G + + V EP +G P +P Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYV-------EPAAPLGAPTYIP 1348 Score = 40.4 bits (93), Expect = 0.013 Identities = 21/71 (29%), Positives = 32/71 (45%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ +G + V G PDPE W+KN I+ S+ + + I+ VT+EDS Sbjct: 2042 TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2101 Query: 1415 KYSINIKNKYG 1425 + N G Sbjct: 2102 SIMVKAINIAG 2112 Score = 40.4 bits (93), Expect = 0.013 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 18/121 (14%) Query: 1332 QFKAAAFAEKNRG--RLIG--------------GLP-DVVTIMEGKTLNLTCTVFGNPDP 1374 QF+ A+ EK + R++G LP + +I G+ L + V G P P Sbjct: 17785 QFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17844 Query: 1375 EVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVS 1434 + W K+ + ++ + +V+ E A + IK +D GKY++ N G +++V Sbjct: 17845 NISWVKDGEPLKQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 17903 Query: 1435 V 1435 V Sbjct: 17904 V 17904 Score = 40.0 bits (92), Expect = 0.017 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + ++EG+ L++ P P V W K+ ++++ S+ ++K + K V + D+ Sbjct: 7899 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DA 7957 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y+I ++NK G + V V Sbjct: 7958 GIYTITLENKLGSATASINVKV 7979 Score = 40.0 bits (92), Expect = 0.017 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1344 GRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY-VS 1402 G L L + + G T+ L V G P P++ W K ++ L + + ++ + Sbjct: 13196 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSK--PNVNLRDRIGLDIKSTDFDTF 13253 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 + + V D+GKY + ++N G ++ + V V Sbjct: 13254 LRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286 Score = 40.0 bits (92), Expect = 0.017 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ + + G P P V W K+++++ +S++ + + +TI VT D+GKY + Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKYIL 20847 Query: 1419 NIKNKYGGEKIDVTVSV 1435 I+N G K TVSV Sbjct: 20848 TIENGVGEPK-SSTVSV 20863 Score = 39.7 bits (91), Expect = 0.022 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 27/191 (14%) Query: 1263 NWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQA 1322 +W A + S ++ GGS+ ++ K++GK +E GKD R L Sbjct: 9934 DWTKSSADLEWSPPLKDGGSKVTGYIV----EYKEEGKEEWE--KGKDKEVRGTKLVVTG 9987 Query: 1323 FDE-AFAEFQ--QFKAAAFAEKN--------RGRLIG-------GLPDVVTIMEGKTLNL 1364 E AF +F+ A E + RL+ + D + + G + + Sbjct: 9988 LKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRI 10047 Query: 1365 TCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKY 1424 V G P P V W N++ L + +++ A SM IK G YS+ KN+ Sbjct: 10048 IAYVSGKPPPTVTWNMNER--TLPQEATIET-TAISSSMVIKNCQRSHQGVYSLLAKNEA 10104 Query: 1425 GGEKIDVTVSV 1435 G K + V V Sbjct: 10105 GERKKTIIVDV 10115 Score = 39.3 bits (90), Expect = 0.028 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + +G + LT + G P P W K QDI S+ + + + + IK DS Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSET-HTELVIKEADRGDS 23705 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y + ++NK G + + + V V Sbjct: 23706 GTYDLVLENKCGKKAVYIKVRV 23727 Score = 39.3 bits (90), Expect = 0.028 Identities = 60/321 (18%), Positives = 118/321 (36%), Gaps = 50/321 (15%) Query: 68 CRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKL- 126 C++ K + ++ E Q+ ++ S + +A Q +S+ A E++ ++ +++++KL Sbjct: 26440 CKLTIKAI--KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLA 26497 Query: 127 -----DKYAIQQMMEDKLAW--ERHTFEERISRAPEILVRLRSHTVWERMSV-------- 171 K I + ++ A E+ E I++ + +R+H + S Sbjct: 26498 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQ 26557 Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 +L V+W +G + + E YR + TL I +A D + ++ Sbjct: 26558 RLVLKANIAGATDVKWVLNGVELTNSEE---YRYGVSGSDQTLTIKQASHRDEGILTCIS 26614 Query: 232 TNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRRE 291 G V + + + D F I P S I E Sbjct: 26615 KTKEGIVKCQYDLTLSKELSDAPAF------ISQPRSQNI------------------NE 26650 Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 G+ V C + P P EW+++++ + S + SL + D G Sbjct: 26651 GQNVLFTCEISGEPS-----PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26705 Query: 352 LYTLRIVSRGGVSDHSAFLFV 372 YT++ + G +A L V Sbjct: 26706 KYTIKAKNFRGQCSATASLMV 26726 Score = 38.9 bits (89), Expect = 0.037 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK---YVSMTIKGVTS 1410 + + G + + G P PE+ W + + + F+ KV+ K Y ++I Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGE------FTDKVQIEKGVNYTQLSIDNCDR 17590 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPK 1454 D+GKY + ++N G + VTV V + PPQ K Sbjct: 17591 NDAGKYILKLENSSGSKSAFVTVKV------LDTPGPPQNLAVK 17628 Score = 38.5 bits (88), Expect = 0.048 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT+ G ++L G P P + W K+ ++ SE + K ++++IK E Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK-ITLSIKNAKKEHG 21134 Query: 1414 GKYSINIKNKYGGEKIDVTV 1433 GKY++ + N + +TV Sbjct: 21135 GKYTVILDNAVCRIAVPITV 21154 Score = 38.5 bits (88), Expect = 0.048 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-DSGKYS 1417 G TL L G P P + WF + +Q SE+ +++ Y + +K V + +GKY Sbjct: 24146 GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE-NTEHYTHLVMKNVQRKTHAGKYK 24204 Query: 1418 INIKNKYG 1425 + + N +G Sbjct: 24205 VQLSNVFG 24212 Score = 38.1 bits (87), Expect = 0.063 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 172 KLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVA 231 K +Q P QW+K G I E K I S+ + +LEI R D Y+ A Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIY---ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4411 Query: 232 TNAHGQVSTNAAVVV 246 +N +G VS A + V Sbjct: 4412 SNEYGSVSCTATLTV 4426 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQL-SEHFSVKVEQAK----YVSMTIK 1406 D + + G+ +++ V G P P++ W KN+ I+ ++ + E+ ++I Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 8968 Query: 1407 GVTSEDSGKYSINIKNKYGGEKIDVTVSVY 1436 ED G Y++ N+ G +V V VY Sbjct: 8969 KAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D V + G+ L V G P P + W K+ ++++ + +K+ ++ K T Sbjct: 14972 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS-TNLVNKDSTRR 15030 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSV 1435 DSG Y++ N G K V V Sbjct: 15031 DSGAYTLTATNPGGFAKHIFNVKV 15054 Score = 38.1 bits (87), Expect = 0.063 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS-MTIKGVTSEDS 1413 T++ G+ L + G P P V W K+ ++ L + V E + S +TIK ED Sbjct: 15661 TVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKDACREDV 15718 Query: 1414 GKYSINIKNKYG 1425 G Y + + N G Sbjct: 15719 GHYVVKLTNSAG 15730 Score = 37.0 bits (84), Expect = 0.14 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V + G + L V G P P+V W K D + + V+ + + I T +D Sbjct: 12118 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF--LVIPNSTRDD 12175 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDM 1445 SGKYS+ + N G + + V V V + D+ Sbjct: 12176 SGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 12208 Score = 37.0 bits (84), Expect = 0.14 Identities = 16/79 (20%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 ++ G+ L + + G P P + W K+ ++ + +V + +++IK +D G Sbjct: 16743 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGG 16801 Query: 1415 KYSINIKNKYGGEKIDVTV 1433 +Y I + N G + + + Sbjct: 16802 QYGITVANVVGQKTASIEI 16820 Score = 37.0 bits (84), Expect = 0.14 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 907 VEARPGTKEISAGVDEQGNIYLGFDC--QEMTDASQFTWCKSYEEISDDERFKIETVGDH 964 +E P + +I V E+G ++ + C + ++Q TW ++ + E+++I Sbjct: 25068 IEIGPVSGQIMHAVGEEGG-HVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV 25126 Query: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSF 994 + LY+K+ K D GTY V + G SS+ Sbjct: 25127 AILYVKDITKLDDGTYRCKVVNDYGEDSSY 25156 Score = 36.6 bits (83), Expect = 0.18 Identities = 110/564 (19%), Positives = 213/564 (37%), Gaps = 96/564 (17%) Query: 879 QGKTYVFRVRAVNANGVGKP-------SDTSEPVLVEARP--GTKEISAGVDEQGNIYLG 929 +GKT+ ++ V + + + S T++ ++EA P K E+ I L Sbjct: 5127 EGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITL- 5185 Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 C+ D W K EEI ++ I+ G L +K D +D G Y V TD Sbjct: 5186 -KCEVSKDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY-VCDCGTDK 5242 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRF 1049 ++ ++ RL+ + + + + +EI E PD ++ Sbjct: 5243 TKANVTVEA----RLIKVEKPLYGVEVFVGETAHFEI------------ELSEPDVHGQW 5286 Query: 1050 IINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDA 1109 + + ++ S I D I+ ++ + G + Q + K+ + + + Sbjct: 5287 KLKGQPLTASPDCEIIEDGKKHIL--ILHNCQLGMTGEVSFQAANAKSAANLKVKELPLI 5344 Query: 1110 FKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVL 1169 F T L + + V E+ E + C+V+ K F+WLK Sbjct: 5345 FITPLSDVK---------------------VFEKDEAKFECEVSREPK--TFRWLKG--- 5378 Query: 1170 YETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS--ILEIAGKVYDDMILAM 1227 T+ + +R EL+ KD ++ +K +D + + E K + L + Sbjct: 5379 --TQEITGDDR--FELI------KDGTKHSMVIKSAAFEDEAKYMFEAEDK-HTSGKLII 5427 Query: 1228 SRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAW 1287 + K +PLK + E ++ D ++V W D ++ ++ + + Sbjct: 5428 EGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSM-------- 5479 Query: 1288 LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLI 1347 +D+GK F KD S+D + Q EA + K + Sbjct: 5480 --------QDEGKTHSITF--KD---LSIDDTSQIRVEAMGMSSEAKLTVL--EGDPYFT 5524 Query: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKG 1407 G L D + + + + L C + D V WFK+ ++I+ S++ +K + K + + +K Sbjct: 5525 GKLQDYTGVEKDEVI-LQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADGKKRM-LILKK 5581 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDV 1431 D G+Y+ + K+D+ Sbjct: 5582 ALKSDIGQYTCDCGTDKTSGKLDI 5605 Score = 36.6 bits (83), Expect = 0.18 Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 24/144 (16%) Query: 186 QWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 +W+++ I ++ KY I V+TL I A DD A Y+ TN G+ +AA + Sbjct: 6174 KWFRNEEAIFDSS---KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANL 6230 Query: 246 VRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTF--RREGETVTLKCTM-- 301 + +EE R V PL D++ +EK VTF + VTLK T Sbjct: 6231 I----VEEEDLRIVE-----PLK--------DIETMEKKSVTFWCKVNRLNVTLKWTKNG 6273 Query: 302 LVTPDLKRVQPRAEWYRDDVLLKE 325 P RV R + Y+ + +K+ Sbjct: 6274 EEVPFDNRVSYRVDKYKHMLTIKD 6297 Score = 36.6 bits (83), Expect = 0.18 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 1370 GNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV-SMTIKGVTSEDSGKYSINIKNKYGGEK 1428 G P V W K+ Q L E V V +K V S++IK + ED G Y + + N G Sbjct: 18923 GRPQATVNWRKDGQT--LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 18980 Query: 1429 IDVTVSV 1435 + +T+ V Sbjct: 18981 VPITIIV 18987 Score = 36.6 bits (83), Expect = 0.18 Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK--YVSMTIKGVTSEDSGKYSINIK 1421 L C V G+P P V W++ ++I +++ ++++ K Y + I VT +D+ Y + Sbjct: 24450 LVCKVTGHPKPIVKWYRQGKEI-IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRAT 24508 Query: 1422 NKYG 1425 N+ G Sbjct: 24509 NQGG 24512 Score = 36.2 bits (82), Expect = 0.24 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 +V G + + V G P P V W K DQ ++ ++ + + + + I D Sbjct: 14577 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECVRSD 14635 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVY 1436 SG Y + +N G +T+ V+ Sbjct: 14636 SGPYPLTARNIVGEVGDVITIQVH 14659 Score = 36.2 bits (82), Expect = 0.24 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 VT G+ L+C + G P P++ W++ +++ S + + + + ++T+ ED Sbjct: 24045 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH-TLTVMTEEQEDE 24103 Query: 1414 GKYSINIKNKYG 1425 G Y+ N+ G Sbjct: 24104 GVYTCIATNEVG 24115 Score = 35.4 bits (80), Expect = 0.41 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212 AP + + + E SV V G P P V W K G + YR + +Y Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-----YRYKVSYNKQ 1089 Query: 213 T----LEINRADFDDTATYSAVATNAHGQVSTNAAVV 245 T L I+ DD Y+ V N HG+ S +A+++ Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1126 Score = 35.4 bits (80), Expect = 0.41 Identities = 46/222 (20%), Positives = 81/222 (36%), Gaps = 34/222 (15%) Query: 145 TFEERISRA--PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGK 202 T E ++ R P +++ S E + + V G P P W+ DG I K Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVN-DYTHK 1458 Query: 203 YRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLP 262 I+ + G +L I A D+ ++ VA N G+ S + + V +P Sbjct: 1459 VVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKP------- 1510 Query: 263 IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVL 322 F+EK +EG + +K P+ P W ++ + Sbjct: 1511 ----------------MFVEKLKNVNIKEGSRLEMKVRATGNPN-----PDIVWLKNSDI 1549 Query: 323 LKESKWTKMFF--GEGQASLSFSHLHKDDEGLYTLRIVSRGG 362 + K+ K+ +G+A+L D YT +++ G Sbjct: 1550 IVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1591 Score = 35.0 bits (79), Expect = 0.53 Identities = 55/234 (23%), Positives = 82/234 (35%), Gaps = 50/234 (21%) Query: 185 VQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAV 244 V+W+KDG+ I + KY I S V L IN+ DD A YS A Sbjct: 5907 VKWFKDGAEIKKGK---KYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR--------- 5954 Query: 245 VVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVT 304 S M+ + F + E +T+ L C + Sbjct: 5955 ----------------------TSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV--- 5989 Query: 305 PDLKRVQPRAE--WYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR-- 360 +P AE WY+ D + E+ ++ + L + H +D G Y R+ S Sbjct: 5990 -----SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRT 6044 Query: 361 -GGVSDHS-AFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES 412 G V H A F+ L G + C +++ V WK + T ES Sbjct: 6045 DGKVKVHELAAEFISKPQNLEI-LEGEKAEFVC-SISKESFPVQWKRDDKTLES 6096 Score = 34.7 bits (78), Expect = 0.69 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 175 FTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESN-YGVHTLEINRADFDDTATYSAVATN 233 +TV G P P V W+K+ +C + Y I N G T +N +D+ Y A N Sbjct: 3596 YTVVGEPAPTVTWFKENKQLCTSV---YYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652 Query: 234 AHGQVSTNAAVVV 246 G+ + A ++V Sbjct: 3653 MLGESTCAAELLV 3665 Score = 33.9 bits (76), Expect = 1.2 Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 1367 TVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 TV G P P V WFK ++ + S ++++ + + EDSG Y +N G Sbjct: 3597 TVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3655 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1345 RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMT 1404 R + L + VT+++G+ L L+C + N + +V+W K+ + + V ++T Sbjct: 4716 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4773 Query: 1405 IKGVTSEDSGKYSINIKN 1422 I D+G Y++ ++N Sbjct: 4774 INDADDTDAGTYTVTVEN 4791 Score = 33.1 bits (74), Expect = 2.0 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 3/93 (3%) Query: 154 PEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHT 213 P + + TV +K+ G PTP V W+KD + Q E+N Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN---SL 15707 Query: 214 LEINRADFDDTATYSAVATNAHGQVSTNAAVVV 246 L I A +D Y TN+ G+ V+V Sbjct: 15708 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 28/108 (25%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQ--------------------DIQLSEHFSVKV 1395 + G + L ++ G+P P + W K++ ++Q E F + + Sbjct: 8194 VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPL 8253 Query: 1396 EQAKYVSMTIKGVTS--------EDSGKYSINIKNKYGGEKIDVTVSV 1435 Q + + KG + D G Y I ++N +G K TVSV Sbjct: 8254 TQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301 Score = 32.0 bits (71), Expect = 4.5 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK-------NDQDIQLSEHFSVKVEQAKYVS 1402 L + + + EG +N+ + G P P + WFK N + + H + K+ + Sbjct: 9625 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9683 Query: 1403 MTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 + I D+G Y+I N G ++ ++V G P + P Sbjct: 9684 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL--GRPGPPVGP 9726 Score = 32.0 bits (71), Expect = 4.5 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G ++ + + G P PEV W K+ +I L +++ ++ + + I D+ Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTES-FTLLIIPECNRYDT 14345 Query: 1414 GKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 GK+ + I+N G + V V V + ++ P K Sbjct: 14346 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITK 14384 Score = 32.0 bits (71), Expect = 4.5 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 1364 LTCTVFGNP--DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIK 1421 LTC V + EV W+K+ + ++ + HF + I +T D G+Y I Sbjct: 26238 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 26297 Query: 1422 NKYGGEKIDV 1431 + G K ++ Sbjct: 26298 GEGGTSKTNL 26307 >gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] Length = 1326 Score = 168 bits (426), Expect = 3e-41 Identities = 136/597 (22%), Positives = 239/597 (40%), Gaps = 45/597 (7%) Query: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371 P+ WY+D + + E + M GE QA L+ S+ ++D GL L++ + G + + L Sbjct: 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696 Query: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431 V D G ++ + + V + WK P PV + V+R VG +W++ Sbjct: 697 VLDRPKPPQGR------VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK 750 Query: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491 + K+ + + EG++Y FR+ AVNS G+S P + A +P+ Sbjct: 751 IGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG-NPI---------- 799 Query: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550 + PG + +++++ V ++W PT G P++ Y +E+ Sbjct: 800 -----------------EPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842 Query: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610 GS W VN + ++ + V L+E Y FRV++ N+ G +PS +S + A+D Sbjct: 843 KGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901 Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670 P + S ++ +S+ + W P + GY ++ T W C PI + Sbjct: 902 PPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961 Query: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730 V GL ++Y FR++AVN G+ E + ++ P L + Sbjct: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTA 1021 Query: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790 + GSP K V K + S + L ++ ++I N Sbjct: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL-INSTKRSDSGVYRILLQNE 1080 Query: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850 G + P P +L E ++ + W + Y + Sbjct: 1081 FG-------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133 Query: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907 R+ W T + +N+Y V+ L G+ Y FRV A N G +P D+ + L+ Sbjct: 1134 KRDASTATWYTAAERVFSNKY-TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI 1189 Score = 152 bits (383), Expect = 3e-36 Identities = 153/646 (23%), Positives = 259/646 (40%), Gaps = 78/646 (12%) Query: 612 PSAP-GRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 P P GRV + + V ++W PK + + V+ G W Sbjct: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT----LLNCDG 724 F + + G+ Y FR+ AVN+ G+S+ + +V P P G + + Sbjct: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGN-----PIEPPGFASQPQVTDVTK 815 Query: 725 HSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFK 784 ++T+ W P GG+P+LGY +++R+ W VN P + T TVDGL E + YEF+ Sbjct: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFR 875 Query: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844 + AVN AG G+PS PS + P PG DL + ++S+ + W+ P + P Sbjct: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKP-PGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932 Query: 845 SGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 SGY ++ R ED EW + + V L + + Y FR+RAVN GVG+P + + Sbjct: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992 Query: 905 VLVEARPGTKEISAGVDEQGN----------IYLGFDCQEMTDASQFTWCKSYEEISDDE 954 V P + + + I+ F D W K + + Sbjct: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV---IWQK--DGVPTKG 1047 Query: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVS--------SSFVLDPEELERLMA 1006 R I +HS+ + + + D G Y + + + G + + F P L Sbjct: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLR---- 1103 Query: 1007 LSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSD----SEIH 1062 L E+ N T+ L W + + D +II R+ S + Sbjct: 1104 LFEEVPN-TVTLT---------------WNHSPDVQEDGEAHYIIMKRDASTATWYTAAE 1147 Query: 1063 RIKCDK--ATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQ 1120 R+ +K TG++ F + +I D + LI K +++ + Sbjct: 1148 RVFSNKYTVTGLLPGRKYYFRVVARN----EIGDSEPLDSRDTWLIN---KDQIQDLSAK 1200 Query: 1121 RKEFLRKQGPHFAEYL----HWDVTEECEVRLVCKVANTKKETVFKWLKD-DVLYETETL 1175 K + +K H ++ V + + C + TV + D ++ ++ Sbjct: 1201 LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW 1260 Query: 1176 PNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYD 1221 N G+C L+IP + KD G+Y ++++ G+D S + VYD Sbjct: 1261 YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT--VYD 1304 Score = 133 bits (335), Expect = 1e-30 Identities = 160/665 (24%), Positives = 258/665 (38%), Gaps = 108/665 (16%) Query: 154 PEILVRLRSHTVWERMS----VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 P +L L +H + ++ +K+ F +G P P V WYKDG + E + +E Sbjct: 606 PSVLEALAAHAITVKVGHTAHIKVPF--RGKPLPKVTWYKDG---MEVTEEERVSMERGE 660 Query: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269 L I+ +D+ N HG + + V + P G Sbjct: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL-----DRPKPPQG--------- 706 Query: 270 MIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWT 329 V+FLE G V +K P +P ++ + + + W Sbjct: 707 -------RVEFLE-------LSGSCVHMKWK---APKDNGGRPVTQFIVERRAVGKKSWI 749 Query: 330 KMFFGEGQASLSFSHLHKDDEG-LYTLRI--VSRGGVSDHSAFLFVRDADPLVTGAPGAP 386 K+ GE ++ +K +EG Y RI V+ GVSD V +P+ PG Sbjct: 750 KI--GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI--EPPGFA 805 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 Q D ++ V +TW P +PV+GY V+R + G+N WV N P++ K V G Sbjct: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L E Y FRV AVN AG +PS S +V A DP+ Sbjct: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV------------------------- 900 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566 + PG +H S+ S + + L+W P G P Y +E + W + + + Sbjct: 901 --KPPGLVQDLHVSDSSNSSISLAWREPA-EGDPPSGYILEMRAEDTKEWSKC-TKIPIS 956 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKT 626 Y V L+E + Y FR+ + N G+ EP E+ ++A P+AP L++R K+ Sbjct: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---PPAAPKFDLSAR-LKS 1012 Query: 627 SVVVQWDRPKHEEDLLGYYVDCCVAGTN----LWEPCN---------HKPIGYNRFVVHG 673 +VV+ + +G+ +W+ K +++F+++ Sbjct: 1013 HMVVRAG--------TALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINS 1064 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 + ++R+ N G + I V+ A P P + L +++TL W Sbjct: 1065 TKRSDSGVYRILLQNEFGEARYD-----IHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNH 1118 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 Y + KR+ W+ + TV GL G Y F++ A N G Sbjct: 1119 SPDVQEDGEAHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177 Query: 794 GEPSD 798 EP D Sbjct: 1178 SEPLD 1182 Score = 63.2 bits (152), Expect = 2e-09 Identities = 111/542 (20%), Positives = 197/542 (36%), Gaps = 88/542 (16%) Query: 930 FDC-QEMTDAS-QFTWCKSYEEISDDE---RFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 FDC E+ D + + W K E + ++ ++ +G L + N + D G YS+SV Sbjct: 253 FDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV 312 Query: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEI-FDKGRVRF-W-LQAEHL 1041 D + VLD E L+ L E+K + + +EI K F W + L Sbjct: 313 GDKRMSAELTVLD-EPLKFL----GEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKEL 367 Query: 1042 SPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQS 1101 D Y +++ D H +K A + + G ++ + + K+Q Sbjct: 368 KRDDKYEITVSE----DGLTHTLKIKDAR-----------LSDSGEFSAEAGNLVQKAQL 412 Query: 1102 SLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVF 1161 ++ I F + L+ V E L C++ T K+ Sbjct: 413 TIDRIPIKFVSNLKNVR---------------------VKERSRACLECEL--TSKDVTL 449 Query: 1162 KWLKDD--VLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219 +W KD +++ T+ N E EL+I D GEY D + Sbjct: 450 RWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT--------EY 501 Query: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279 Y I+ + S + + G + + ++++ W +I+ M+I Sbjct: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561 Query: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 + L + +GKYTF G ++ D + E AA A Sbjct: 562 VKQGAVHKLIFPSMGPEHEGKYTFRA-KGTESEASVFIADPPTIDPSVLE----ALAAHA 616 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 +T+ G T ++ G P P+V W+K+ ++ E S++ + + Sbjct: 617 --------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPAS 1459 + +TI EDSG + +KN +G + +SV D P Q + + + S Sbjct: 663 AL-LTISNCVREDSGLILLKLKNDHGSATATLHLSVL-------DRPKPPQGRVEFLELS 714 Query: 1460 AS 1461 S Sbjct: 715 GS 716 Score = 52.8 bits (125), Expect = 2e-06 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T++ G+ +TC GNP P V +K D +I + F + ++ I T +DSG Sbjct: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKDSG 1281 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEK 1441 YS+ ++N+ G ++ T++VY +K Sbjct: 1282 DYSVLVENELGKDRSSCTLTVYDKDDK 1308 Score = 38.1 bits (87), Expect = 0.063 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 4/128 (3%) Query: 120 SQARDKLDKYAIQQMMEDKLAWERHTFEERISR-APEILVRLRSHTVWERMSVKLCFTVQ 178 S+ D D + I + L+ + +E++ R AP + L+ HTV + Sbjct: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFL 1237 Query: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238 G P P V YK I K+ S GV TL I D+ YS + N G+ Sbjct: 1238 GNPRPTVTLYKGDVNI---TANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKD 1294 Query: 239 STNAAVVV 246 ++ + V Sbjct: 1295 RSSCTLTV 1302 Score = 37.7 bits (86), Expect = 0.082 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 + + G L + G+P P+VIW K+ + E + ++++ I DS Sbjct: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL---INSTKRSDS 1070 Query: 1414 GKYSINIKNKYGGEKIDVTVSV 1435 G Y I ++N++G + D+ V V Sbjct: 1071 GVYRILLQNEFGEARYDIHVRV 1092 Score = 32.3 bits (72), Expect = 3.4 Identities = 24/103 (23%), Positives = 40/103 (38%), Gaps = 6/103 (5%) Query: 901 TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-QFTWCKSYEEISDDERFKIE 959 T E L + G ++ A + C + D + W K +EI+D +I Sbjct: 508 TVEERLATVKSGMSDVHAATGSPAEL-----CVVLNDEKVEGVWLKDGKEITDLPGMQIV 562 Query: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELE 1002 G KL + E G Y+ T+ +S F+ DP ++ Sbjct: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605 Score = 32.0 bits (71), Expect = 4.5 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 8/109 (7%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVT 1409 P VT EG V GN P + W K + I + E + + K + ++ +T Sbjct: 73 PQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVLKLEPLT 131 Query: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEK------IPDMAPPQQAK 1452 S+DS Y N + V++ V + EK + APP K Sbjct: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180 Score = 32.0 bits (71), Expect = 4.5 Identities = 28/117 (23%), Positives = 55/117 (47%), Gaps = 7/117 (5%) Query: 879 QGKTYVFRVRAVNANGVGKPSD--TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMT 936 +GK Y FR + + +D T +P ++EA I+ V +I + F + + Sbjct: 580 EGK-YTFRAKGTESEASVFIADPPTIDPSVLEAL-AAHAITVKVGHTAHIKVPFRGKPLP 637 Query: 937 DASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993 + TW K E++++ER +E D + L + N +ED G + + + G +++ Sbjct: 638 ---KVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691 >gi|148839296 immunoglobulin-like and fibronectin type III domain containing 1 [Homo sapiens] Length = 868 Score = 154 bits (388), Expect = 8e-37 Identities = 153/608 (25%), Positives = 237/608 (38%), Gaps = 71/608 (11%) Query: 313 RAEWYRD--DVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 +A W +D +V+ + ++ G+G L + D G Y++ + S GG L Sbjct: 196 QAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTL 255 Query: 371 FVRDA-DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNW 429 V D DP P PM++Q D +R V + W+PP V Y V+R + G + W Sbjct: 256 QVIDKPDP-----PQGPMEVQ--DCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTW 308 Query: 430 VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAV 489 ++ +AP + + GR Y FRVRAV S Sbjct: 309 LKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTS--------------------------- 341 Query: 490 HLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEK 548 EG E ++ L +P P+ S + L+W P G ++ Y IE+ Sbjct: 342 --EGAGEALESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIER 399 Query: 549 SVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDV 608 GS +W VN Q V R+ V D+ +G Y FRV + G EP + + A+D Sbjct: 400 RKKGSNTWTAVNDQ-PVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDP 458 Query: 609 TVVPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGY 666 P + + + TS+ + W P +E + GY V+ C + + W PC+ + Sbjct: 459 MRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPV 518 Query: 667 NRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHS 726 + GL GE Y RV AVN G S+ S +++ P + + D + Sbjct: 519 TTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPK--FLVDSSTKDLLT 576 Query: 727 MTLG--WKVPKFSGGSPIL-------GYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTE 777 + +G +VP P+ G L KR V V ++ V GL++ Sbjct: 577 VKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSV------TVTKDGLTQLLIPVAGLSD 630 Query: 778 GSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE-PGPAYDLTFCEVRDTSLVMLWKAP 836 LY + + + + + F+ P+ PGP + E ++ W+ Sbjct: 631 SGLYTVVLRTL------QGKEVAHSFRIRVAACPQAPGPIH---LQENVPGTVTAEWEPS 681 Query: 837 VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG 896 Y V R G W NR+ + L G Y FRV A N G Sbjct: 682 PDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLLGIL-PGHEYHFRVVAKNELGAS 740 Query: 897 KPSDTSEP 904 KPSDTS+P Sbjct: 741 KPSDTSQP 748 Score = 145 bits (366), Expect = 3e-34 Identities = 175/702 (24%), Positives = 280/702 (39%), Gaps = 87/702 (12%) Query: 555 SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANR------------HGLSEPSEITSP 602 +W++ A+ S R A DL +G + + + SA R G S +E+T Sbjct: 198 AWRKDGAEVVGSSDREAQVDLGDGYTRLC-LPSAGRKDCGQYSVTLRSEGGSVQAELT-- 254 Query: 603 IQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCV-----AGTNLWE 657 +Q D P P V + V ++W P+ D G V+C V AG + W Sbjct: 255 LQVIDKPDPPQGPMEVQDCH--RAGVCLRWRPPR---DNGGRTVECYVVERRQAGRSTWL 309 Query: 658 PCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI 717 P F + G +Y FRV+AV + G E + +++ AL P P Sbjct: 310 KVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEAL--PKAPSAP 367 Query: 718 TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTE 777 +L+ +TL W P+ G + ILGY +++R+ W VN P TV + + Sbjct: 368 AILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQ 427 Query: 778 GSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPV 837 G YEF++ AV +G GEP PS+ M PG +L + +TS+ + W P Sbjct: 428 GCQYEFRVTAVAPSGPGEPGPPSDAVFARD-PMRPPGLVRNLQVTDRSNTSITLSWAGPD 486 Query: 838 YSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK 897 GY V+ D+ +W+ + T L+ G+ Y RV AVN G + Sbjct: 487 TQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQ 546 Query: 898 PSDTSEPVLVEARP-----------GTKE-ISAGVDEQGNIYLGFDCQEMTDASQFTWCK 945 PS + LV+A P TK+ ++ V + + + F+ M + TW K Sbjct: 547 PS--ALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEV---TWLK 601 Query: 946 SYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG--VSSSFVLDPEELER 1003 + + +R T ++L + D G Y+V + G V+ SF + Sbjct: 602 --DGLPLPKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRI------- 652 Query: 1004 LMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIH- 1062 +A + P I L+ + + + W + + D + + R + H Sbjct: 653 RVAACPQAPGP-IHLQENVPGTVTAE-----WEPSPDEAQDVPLHYAVFTRSSAHGPWHE 706 Query: 1063 ---RIKCDKAT--GIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEA 1117 RI ++ T GI+ F + + ++ K S I +A Sbjct: 707 AADRIHTNRFTLLGILPGHEYHFRVVAKN----ELGASKPSDTSQPWCIPRQRDRFTVKA 762 Query: 1118 EFQRKEFLRKQGPHFAEYLHWDVTEE-CEVRLVCKVANTKKETVFKWLKDD-------VL 1169 R+ L Q P F L + + CE + C V + + V W K+D + Sbjct: 763 PCYREPDL-SQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHV-TWFKNDRSLEGNPAV 820 Query: 1170 YETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS 1211 Y T+ L G+C L IP +S KD GEYKA ++ GQ VS Sbjct: 821 YSTDLL-----GVCSLTIPSVSPKDSGEYKAVAENTLGQAVS 857 Score = 48.9 bits (115), Expect = 4e-05 Identities = 36/101 (35%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYK-DGSLICQAAEPGKYRI 205 E +S+ P LV LRSH + + + VQG P P V W+K D SL P Y Sbjct: 767 EPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSL---EGNPAVYST 823 Query: 206 ESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVV 246 + GV +L I D+ Y AVA N GQ + A ++V Sbjct: 824 DL-LGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIV 863 Score = 43.5 bits (101), Expect = 0.001 Identities = 43/181 (23%), Positives = 67/181 (37%), Gaps = 14/181 (7%) Query: 292 GETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEG 351 G+TV + + P P W +D + L + T G Q + + L D G Sbjct: 580 GDTVRVPVSFEAMP-----MPEVTWLKDGLPLPKRSVTVTKDGLTQLLIPVAGL--SDSG 632 Query: 352 LYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 LYT+ + + G +F V P AP + + V W+P + Sbjct: 633 LYTVVLRTLQGKEVAHSFRI------RVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQ 686 Query: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRV 471 + Y V W + D + ++ + G+ G Y FRV A N G S+PS Sbjct: 687 DVPLHYAVFTRSSAHGPWHEAADR-IHTNRFTLLGILPGHEYHFRVVAKNELGASKPSDT 745 Query: 472 S 472 S Sbjct: 746 S 746 Score = 42.7 bits (99), Expect = 0.003 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNK 1423 ++C V G+P P V WFKND+ ++ + S+TI V+ +DSG+Y +N Sbjct: 793 MSCAVQGSPRPHVTWFKNDRSLE-GNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENT 851 Query: 1424 YG 1425 G Sbjct: 852 LG 853 Score = 31.2 bits (69), Expect = 7.7 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 3/76 (3%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 D++T+ G T+ + + P PEV W K+ + SV V + + I Sbjct: 573 DLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKR---SVTVTKDGLTQLLIPVAGLS 629 Query: 1412 DSGKYSINIKNKYGGE 1427 DSG Y++ ++ G E Sbjct: 630 DSGLYTVVLRTLQGKE 645 >gi|46049110 myosin binding protein C, slow type isoform 4 [Homo sapiens] Length = 1123 Score = 137 bits (345), Expect = 8e-32 Identities = 218/984 (22%), Positives = 360/984 (36%), Gaps = 181/984 (18%) Query: 64 GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120 G T R KR+ EE+++ + + L AY K R RF+ ELA + +V ++ Sbjct: 230 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 289 Query: 121 QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161 Q KY + QM +D A + E R P I+V +L Sbjct: 290 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 349 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221 T + V+L V V +W+K+G I + +YRI H L I A Sbjct: 350 DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 407 Query: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281 D A YS + T GQ S +V ++ PL + P T V Sbjct: 408 ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 446 Query: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341 G+ + LKC ++ P +W ++ + ++ES K+ L Sbjct: 447 ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 489 Query: 342 FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393 ++ +DEG Y + + ++ V D + DAD VT G + L+ Sbjct: 490 IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 549 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 + PP + T ++ + + I + +G Sbjct: 550 SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 595 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 ++ + N AG E I + D P P Sbjct: 596 VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 622 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +E+ ++ +++WEPP G P++ YFIE+ S W R+N + + Sbjct: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 681 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 ++EG +Y R+ + N G+S+PS + P VT S P + T T+V ++W Sbjct: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 738 Query: 633 DRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 P H L GY ++ C GT W N I +F + GL T + RVKAVNA Sbjct: 739 RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 798 Query: 691 GMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 G SE S I V+ + +P H T + G ++ L +P P L + Sbjct: 799 GASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAVNL--VIPFQGKPRPELTW 855 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D E+ + NS + + Y+ ++ E Sbjct: 856 KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV---------ETASI 906 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQ- 864 + + PGP + +V ++ + W P G++ ++GY + ++ + EW TV + Sbjct: 907 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 966 Query: 865 --TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 T+A +++L G Y FRV + N G+ + + ++ V AR G Sbjct: 967 YHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK-------IY 1015 Query: 923 QGNIYLGFDCQEMTDASQ--------------------------FTWCKSYEEISDDERF 956 + +Y FD E +Q TW K+ I DD R+ Sbjct: 1016 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1075 Query: 957 KIETVGDHSKLYLKNPDKEDLGTY 980 ++ + L ++ P D GTY Sbjct: 1076 RMFSNQGVCTLEIRKPSPYDGGTY 1099 Score = 119 bits (298), Expect = 2e-26 Identities = 129/547 (23%), Positives = 217/547 (39%), Gaps = 54/547 (9%) Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 ++ + N G + S IKV+ + P P T+ + W+ P + GGS Sbjct: 596 VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PILGY++++++ W +N K T + EG YE +I AVN GI +PS PS Sbjct: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 F A T P P LT V DT++ M W+ P + G++ + GY +++ E +WI Sbjct: 710 RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 765 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----------AR 910 N+ ++ L RV+AVNA G +P S+P+LV+ R Sbjct: 766 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 825 Query: 911 PGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLK 970 + V E N+ + F + + TW K EI D + I + ++++ Sbjct: 826 HLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIR 881 Query: 971 NPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKG 1030 ++ G Y + V D + +D + ++R P +K E +++ + Sbjct: 882 KAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------PGPPQIVKIE---DVWGEN 929 Query: 1031 RVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDKATGIIEMVMDR---FSIE 1083 W + A + I + E I AT I E+V+ F + Sbjct: 930 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT-ITELVIGNEYYFRVF 988 Query: 1084 NEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEFLRKQGPHFAEYLHWDVTE 1142 +E + K + + G +K V E+ +F + + ++ T Sbjct: 989 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1048 Query: 1143 ECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPKLSKKDHGEYKA 1200 C VR N K + W+K+ V + + +G+C L I K S D G Y Sbjct: 1049 NCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1101 Query: 1201 TLKDDRG 1207 +D G Sbjct: 1102 KAVNDLG 1108 Score = 45.4 bits (106), Expect = 4e-04 Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%) Query: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059 L+RL + E K K + AY++ GRVRF + E P ++ N +E+ S Sbjct: 238 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295 Query: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119 + + I+ ++ + ++ Y V D K ++ Sbjct: 296 TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 335 Query: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177 F+R+ + L D T C R+ + ++ + KW K+ E +P Sbjct: 336 ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 386 Query: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231 +E L+I +K D EY S++ G+ S Sbjct: 387 SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 426 Query: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286 PLK+L T + + L C ++ + W + S+ +++ + Sbjct: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 486 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 L I +D+G Y F D + +L D A Sbjct: 487 KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 531 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403 + VT++ G L L + G P P+ +W + D+ I S ++ Y ++ Sbjct: 532 ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 584 Query: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 I +DSG Y IN+KN+ G + V V + P +AP Sbjct: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 626 Score = 40.0 bits (92), Expect = 0.017 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235 +V+G P P + W K+ I + +YR+ SN GV TLEI + D TY A N Sbjct: 1051 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1107 Query: 236 GQVSTNAAVVVR 247 G V + V+ Sbjct: 1108 GTVEIECKLEVK 1119 Score = 35.4 bits (80), Expect = 0.41 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G L C+V GNP P++ W KN I + + Q ++ I+ + D G Y Sbjct: 1043 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1101 Query: 1419 NIKNKYGGEKIDVTVSV 1435 N G +I+ + V Sbjct: 1102 KAVNDLGTVEIECKLEV 1118 Score = 31.2 bits (69), Expect = 7.7 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ +NL G P PE+ W K+ +I ++ +++ + + + I+ SGKY + Sbjct: 836 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 893 Query: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 +K E + + + I PPQ K Sbjct: 894 QVKVDKFVETASIDIQI------IDRPGPPQIVK 921 >gi|46049125 myosin binding protein C, slow type isoform 2 [Homo sapiens] Length = 1148 Score = 137 bits (345), Expect = 8e-32 Identities = 218/984 (22%), Positives = 360/984 (36%), Gaps = 181/984 (18%) Query: 64 GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120 G T R KR+ EE+++ + + L AY K R RF+ ELA + +V ++ Sbjct: 255 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 314 Query: 121 QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161 Q KY + QM +D A + E R P I+V +L Sbjct: 315 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221 T + V+L V V +W+K+G I + +YRI H L I A Sbjct: 375 DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 432 Query: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281 D A YS + T GQ S +V ++ PL + P T V Sbjct: 433 ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 471 Query: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341 G+ + LKC ++ P +W ++ + ++ES K+ L Sbjct: 472 ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 514 Query: 342 FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393 ++ +DEG Y + + ++ V D + DAD VT G + L+ Sbjct: 515 IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 574 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 + PP + T ++ + + I + +G Sbjct: 575 SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 620 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 ++ + N AG E I + D P P Sbjct: 621 VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 647 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +E+ ++ +++WEPP G P++ YFIE+ S W R+N + + Sbjct: 648 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 706 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 ++EG +Y R+ + N G+S+PS + P VT S P + T T+V ++W Sbjct: 707 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 763 Query: 633 DRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 P H L GY ++ C GT W N I +F + GL T + RVKAVNA Sbjct: 764 RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823 Query: 691 GMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 G SE S I V+ + +P H T + G ++ L +P P L + Sbjct: 824 GASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAVNL--VIPFQGKPRPELTW 880 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D E+ + NS + + Y+ ++ E Sbjct: 881 KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV---------ETASI 931 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQ- 864 + + PGP + +V ++ + W P G++ ++GY + ++ + EW TV + Sbjct: 932 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991 Query: 865 --TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 T+A +++L G Y FRV + N G+ + + ++ V AR G Sbjct: 992 YHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK-------IY 1040 Query: 923 QGNIYLGFDCQEMTDASQ--------------------------FTWCKSYEEISDDERF 956 + +Y FD E +Q TW K+ I DD R+ Sbjct: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100 Query: 957 KIETVGDHSKLYLKNPDKEDLGTY 980 ++ + L ++ P D GTY Sbjct: 1101 RMFSNQGVCTLEIRKPSPYDGGTY 1124 Score = 119 bits (298), Expect = 2e-26 Identities = 129/547 (23%), Positives = 217/547 (39%), Gaps = 54/547 (9%) Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 ++ + N G + S IKV+ + P P T+ + W+ P + GGS Sbjct: 621 VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PILGY++++++ W +N K T + EG YE +I AVN GI +PS PS Sbjct: 675 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 F A T P P LT V DT++ M W+ P + G++ + GY +++ E +WI Sbjct: 735 RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----------AR 910 N+ ++ L RV+AVNA G +P S+P+LV+ R Sbjct: 791 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850 Query: 911 PGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLK 970 + V E N+ + F + + TW K EI D + I + ++++ Sbjct: 851 HLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIR 906 Query: 971 NPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKG 1030 ++ G Y + V D + +D + ++R P +K E +++ + Sbjct: 907 KAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------PGPPQIVKIE---DVWGEN 954 Query: 1031 RVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDKATGIIEMVMDR---FSIE 1083 W + A + I + E I AT I E+V+ F + Sbjct: 955 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT-ITELVIGNEYYFRVF 1013 Query: 1084 NEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEFLRKQGPHFAEYLHWDVTE 1142 +E + K + + G +K V E+ +F + + ++ T Sbjct: 1014 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1073 Query: 1143 ECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPKLSKKDHGEYKA 1200 C VR N K + W+K+ V + + +G+C L I K S D G Y Sbjct: 1074 NCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126 Query: 1201 TLKDDRG 1207 +D G Sbjct: 1127 KAVNDLG 1133 Score = 45.4 bits (106), Expect = 4e-04 Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%) Query: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059 L+RL + E K K + AY++ GRVRF + E P ++ N +E+ S Sbjct: 263 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320 Query: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119 + + I+ ++ + ++ Y V D K ++ Sbjct: 321 TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 360 Query: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177 F+R+ + L D T C R+ + ++ + KW K+ E +P Sbjct: 361 ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 411 Query: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231 +E L+I +K D EY S++ G+ S Sbjct: 412 SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 451 Query: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286 PLK+L T + + L C ++ + W + S+ +++ + Sbjct: 452 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 511 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 L I +D+G Y F D + +L D A Sbjct: 512 KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 556 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403 + VT++ G L L + G P P+ +W + D+ I S ++ Y ++ Sbjct: 557 ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 609 Query: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 I +DSG Y IN+KN+ G + V V + P +AP Sbjct: 610 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 651 Score = 40.0 bits (92), Expect = 0.017 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235 +V+G P P + W K+ I + +YR+ SN GV TLEI + D TY A N Sbjct: 1076 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132 Query: 236 GQVSTNAAVVVR 247 G V + V+ Sbjct: 1133 GTVEIECKLEVK 1144 Score = 35.4 bits (80), Expect = 0.41 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G L C+V GNP P++ W KN I + + Q ++ I+ + D G Y Sbjct: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1126 Query: 1419 NIKNKYGGEKIDVTVSV 1435 N G +I+ + V Sbjct: 1127 KAVNDLGTVEIECKLEV 1143 Score = 31.2 bits (69), Expect = 7.7 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ +NL G P PE+ W K+ +I ++ +++ + + + I+ SGKY + Sbjct: 861 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 918 Query: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 +K E + + + I PPQ K Sbjct: 919 QVKVDKFVETASIDIQI------IDRPGPPQIVK 946 >gi|45976288 myosin binding protein C, slow type isoform 1 [Homo sapiens] Length = 1171 Score = 137 bits (345), Expect = 8e-32 Identities = 218/984 (22%), Positives = 360/984 (36%), Gaps = 181/984 (18%) Query: 64 GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120 G T R KR+ EE+++ + + L AY K R RF+ ELA + +V ++ Sbjct: 255 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 314 Query: 121 QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161 Q KY + QM +D A + E R P I+V +L Sbjct: 315 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221 T + V+L V V +W+K+G I + +YRI H L I A Sbjct: 375 DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 432 Query: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281 D A YS + T GQ S +V ++ PL + P T V Sbjct: 433 ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 471 Query: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341 G+ + LKC ++ P +W ++ + ++ES K+ L Sbjct: 472 ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 514 Query: 342 FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393 ++ +DEG Y + + ++ V D + DAD VT G + L+ Sbjct: 515 IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 574 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 + PP + T ++ + + I + +G Sbjct: 575 SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 620 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 ++ + N AG E I + D P P Sbjct: 621 VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 647 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +E+ ++ +++WEPP G P++ YFIE+ S W R+N + + Sbjct: 648 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 706 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 ++EG +Y R+ + N G+S+PS + P VT S P + T T+V ++W Sbjct: 707 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 763 Query: 633 DRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690 P H L GY ++ C GT W N I +F + GL T + RVKAVNA Sbjct: 764 RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823 Query: 691 GMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 G SE S I V+ + +P H T + G ++ L +P P L + Sbjct: 824 GASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAVNL--VIPFQGKPRPELTW 880 Query: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 D E+ + NS + + Y+ ++ E Sbjct: 881 KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV---------ETASI 931 Query: 806 EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQ- 864 + + PGP + +V ++ + W P G++ ++GY + ++ + EW TV + Sbjct: 932 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991 Query: 865 --TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922 T+A +++L G Y FRV + N G+ + + ++ V AR G Sbjct: 992 YHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK-------IY 1040 Query: 923 QGNIYLGFDCQEMTDASQ--------------------------FTWCKSYEEISDDERF 956 + +Y FD E +Q TW K+ I DD R+ Sbjct: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100 Query: 957 KIETVGDHSKLYLKNPDKEDLGTY 980 ++ + L ++ P D GTY Sbjct: 1101 RMFSNQGVCTLEIRKPSPYDGGTY 1124 Score = 119 bits (298), Expect = 2e-26 Identities = 129/547 (23%), Positives = 217/547 (39%), Gaps = 54/547 (9%) Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 ++ + N G + S IKV+ + P P T+ + W+ P + GGS Sbjct: 621 VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PILGY++++++ W +N K T + EG YE +I AVN GI +PS PS Sbjct: 675 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860 F A T P P LT V DT++ M W+ P + G++ + GY +++ E +WI Sbjct: 735 RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790 Query: 861 TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----------AR 910 N+ ++ L RV+AVNA G +P S+P+LV+ R Sbjct: 791 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850 Query: 911 PGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLK 970 + V E N+ + F + + TW K EI D + I + ++++ Sbjct: 851 HLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIR 906 Query: 971 NPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKG 1030 ++ G Y + V D + +D + ++R P +K E +++ + Sbjct: 907 KAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------PGPPQIVKIE---DVWGEN 954 Query: 1031 RVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDKATGIIEMVMDR---FSIE 1083 W + A + I + E I AT I E+V+ F + Sbjct: 955 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT-ITELVIGNEYYFRVF 1013 Query: 1084 NEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEFLRKQGPHFAEYLHWDVTE 1142 +E + K + + G +K V E+ +F + + ++ T Sbjct: 1014 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1073 Query: 1143 ECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPKLSKKDHGEYKA 1200 C VR N K + W+K+ V + + +G+C L I K S D G Y Sbjct: 1074 NCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126 Query: 1201 TLKDDRG 1207 +D G Sbjct: 1127 KAVNDLG 1133 Score = 45.4 bits (106), Expect = 4e-04 Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%) Query: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059 L+RL + E K K + AY++ GRVRF + E P ++ N +E+ S Sbjct: 263 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320 Query: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119 + + I+ ++ + ++ Y V D K ++ Sbjct: 321 TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 360 Query: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177 F+R+ + L D T C R+ + ++ + KW K+ E +P Sbjct: 361 ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 411 Query: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231 +E L+I +K D EY S++ G+ S Sbjct: 412 SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 451 Query: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286 PLK+L T + + L C ++ + W + S+ +++ + Sbjct: 452 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 511 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 L I +D+G Y F D + +L D A Sbjct: 512 KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 556 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403 + VT++ G L L + G P P+ +W + D+ I S ++ Y ++ Sbjct: 557 ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 609 Query: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 I +DSG Y IN+KN+ G + V V + P +AP Sbjct: 610 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 651 Score = 40.0 bits (92), Expect = 0.017 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235 +V+G P P + W K+ I + +YR+ SN GV TLEI + D TY A N Sbjct: 1076 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132 Query: 236 GQVSTNAAVVVR 247 G V + V+ Sbjct: 1133 GTVEIECKLEVK 1144 Score = 35.4 bits (80), Expect = 0.41 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G L C+V GNP P++ W KN I + + Q ++ I+ + D G Y Sbjct: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1126 Query: 1419 NIKNKYGGEKIDVTVSV 1435 N G +I+ + V Sbjct: 1127 KAVNDLGTVEIECKLEV 1143 Score = 31.2 bits (69), Expect = 7.7 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ +NL G P PE+ W K+ +I ++ +++ + + + I+ SGKY + Sbjct: 861 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 918 Query: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 +K E + + + I PPQ K Sbjct: 919 QVKVDKFVETASIDIQI------IDRPGPPQIVK 946 Score = 31.2 bits (69), Expect = 7.7 Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 10/122 (8%) Query: 273 YTHFDVQ----FLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 Y FD F + T+ G TL C++ P +P+ W ++ V + + Sbjct: 1045 YEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNP-----KPKITWMKNKVAIVDDPR 1099 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMD 388 +MF +G +L D G Y + V+ G + L V+ V PG P+ Sbjct: 1100 YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGV-NTPGQPVF 1158 Query: 389 LQ 390 L+ Sbjct: 1159 LE 1160 >gi|133908641 myosin binding protein C, fast type [Homo sapiens] Length = 1141 Score = 132 bits (333), Expect = 2e-30 Identities = 138/525 (26%), Positives = 216/525 (41%), Gaps = 96/525 (18%) Query: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSP 568 VP PP V + + ++ +L WEPP G P+ Y +E+ GS W ++N + + Sbjct: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628 Y ++EG Y RV + N G+S+PS T P T S P ++ T T+ Sbjct: 698 -YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT---SEPLHLIVEDVTDTTT 753 Query: 629 VVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 ++W P + GY V+ C+ G+ W P N +P+ F V L TG + +FRV Sbjct: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813 Query: 687 VNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTL-----GWKVPKF 736 VN G SE + + + ++ + +P H T + G + L G P+ Sbjct: 814 VNIAGRSEPATLAQPVTIREIAEPPKIRLPRH-LRQTYIRKVGEQLNLVVPFQGKPRPQV 872 Query: 737 ---SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 GG+P LD VH + T D T ++ + AA + +G Sbjct: 873 VWTKGGAP-----LDTSRVH---------------VRTSDFDT---VFFVRQAARSDSGE 909 Query: 794 GEPSDPSEHFKCEAW----TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849 E S E+ K A + + GP ++ EV T+ ++ W+AP G+S + GYFV Sbjct: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969 Query: 850 DFREEDAGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907 ++ EW V + NR+ VSDL G Y FRV N G+ SD+ Sbjct: 970 QKADKKTMEWFNVYE---RNRHTSCTVSDLIVGNEYYFRVYTENICGL---SDS------ 1017 Query: 908 EARPGTKEISAGVDEQGNIYLGFDCQE--MTDASQF------------------------ 941 PG + +A + + G + F+ +E A +F Sbjct: 1018 ---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGH 1074 Query: 942 -----TWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS 981 W K+ EI +D +F I L ++ P D GTY+ Sbjct: 1075 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119 Score = 120 bits (302), Expect = 7e-27 Identities = 115/498 (23%), Positives = 198/498 (39%), Gaps = 55/498 (11%) Query: 312 PRAEWYR-DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370 P A W + D+V T++ +S ++DEG YT+++ + G S FL Sbjct: 574 PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633 Query: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 V D P P ++ D+ I+ W+PP PV GY V+R + G+ W+ Sbjct: 634 QVVDV-------PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWM 686 Query: 431 QCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490 + N Y T + EG Y RV AVN+ G+S+PS + + P + +H Sbjct: 687 KLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS----EPLH 742 Query: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKS 549 L E +++ L W PP G + Y +E Sbjct: 743 LIVE--------------------------DVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776 Query: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609 + GS W N + R + V +L G +FRV+ N G SEP+ + P+ +++ Sbjct: 777 LEGSEEWVPANTEPVERC-GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI- 834 Query: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRF 669 + P ++ R+ + + + R E+ L +W P+ +R Sbjct: 835 ---AEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTK-GGAPLDTSRV 886 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTV-----PSHPYGITLLNCDG 724 V + R A + G E S + + +K A + + P + + G Sbjct: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWG 946 Query: 725 HSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFK 784 + + W+ PK G S I+GY++ K + W V ++ T TV L G+ Y F+ Sbjct: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYER-NRHTSCTVSDLIVGNEYYFR 1005 Query: 785 IAAVNLAGIGEPSDPSEH 802 + N+ G+ + S++ Sbjct: 1006 VYTENICGLSDSPGVSKN 1023 Score = 107 bits (267), Expect = 8e-23 Identities = 81/333 (24%), Positives = 140/333 (42%), Gaps = 24/333 (7%) Query: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLN 721 K + + FV+ ++ + +K N VG S V+ V P P + + + Sbjct: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV------PDPPEAVRITS 649 Query: 722 CDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781 L W+ P + GG P+ GY +++++ + W ++N T + EG LY Sbjct: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841 E ++ AVN G+ +PS ++ F A P P + L +V DT+ + W+ P G+ Sbjct: 710 EMRVFAVNAIGVSQPSMNTKPFMPIA---PTSEPLH-LIVEDVTDTTTTLKWRPPNRIGA 765 Query: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901 + GY V++ E + EW+ N V +L G +FRV VN G +P+ Sbjct: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825 Query: 902 SEPVLVEARPGTKEIS----------AGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEIS 951 ++PV + +I V EQ N+ + F + Q W K + Sbjct: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---QGKPRPQVVWTKGGAPL- 881 Query: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984 D R + T + +++ + D G Y +SV Sbjct: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914 Score = 74.7 bits (182), Expect = 6e-13 Identities = 114/532 (21%), Positives = 190/532 (35%), Gaps = 83/532 (15%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 ++L ++ G P PV W K + G+ RIE + I A +D Y+ Sbjct: 562 LRLDVSITGEPPPVATWLKGDEVF--TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619 Query: 231 ATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR 290 TN G+ + + V E R + + P + + + + V ++ Sbjct: 620 VTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKK 679 Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 +G +W K+ F E ++ + Sbjct: 680 KG--------------------------------SQRWMKLNF-EVFTETTYESTKMIEG 706 Query: 351 GLYTLRI--VSRGGVSDHSAFLFVRDADPLVTGAP-GAPMDLQCHDANRDYVIVTWKPPN 407 LY +R+ V+ GVS S + P + AP P+ L D + W+PPN Sbjct: 707 ILYEMRVFAVNAIGVSQPS-----MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPN 761 Query: 408 TTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISR 467 + GY V+ C G+ WV N PV+ C + V L G +FRV VN AG S Sbjct: 762 RIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSE 821 Query: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527 P+ ++ V + + +++ + I + L G P R V Sbjct: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP---------RPQV 872 Query: 528 VLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLS 587 V W +G PL RV+ +T+ + V S + LS Sbjct: 873 V--W----TKGGAPL------------DTSRVHVRTSDFDTVFFVRQAARSDSGEYE-LS 913 Query: 588 ANRHGLSEPSEITSPIQAQDVTVVPSA--PGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643 + + + I + VV A P V+ T+ +V+W PK + +++G Sbjct: 914 VQIENMKDTATIR-------IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966 Query: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSEN 695 Y+V T W ++ + V L G +Y FRV N G+S++ Sbjct: 967 YFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS 1017 Score = 50.1 bits (118), Expect = 2e-05 Identities = 42/155 (27%), Positives = 68/155 (43%), Gaps = 13/155 (8%) Query: 469 SRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQV-------PGPPTGVHASE 521 SRV + D + R A GE E+++ ++++ A + GPP V E Sbjct: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943 Query: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++ W+ P G +M YF++K+ + W V + R V DL+ G Sbjct: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNE 1001 Query: 581 YVFRVLSANRHGLSEP---SEITSPIQAQDVTVVP 612 Y FRV + N GLS+ S+ T+ I +T P Sbjct: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036 Score = 45.8 bits (107), Expect = 3e-04 Identities = 40/160 (25%), Positives = 61/160 (38%), Gaps = 15/160 (9%) Query: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF------VRDADPL--- 378 WTK G A L S +H T+ V + SD + ++D + Sbjct: 874 WTK-----GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928 Query: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438 V G P+++ + +V W+ P S +MGYFV + + T W + + Sbjct: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-R 987 Query: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478 V+ L G Y FRV N G+S VS A + Sbjct: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027 Score = 44.3 bits (103), Expect = 9e-04 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 6/101 (5%) Query: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411 + + ++ G L L ++ G P P W K D+ +E + ++ S I+ E Sbjct: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611 Query: 1412 DSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 D G+Y+I + N G + S++ +PD PP+ + Sbjct: 612 DEGRYTIKVTNPVGED----VASIFLQVVDVPD--PPEAVR 646 Score = 42.4 bits (98), Expect = 0.003 Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 3/101 (2%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 E AP+ L L V S L V+G P P V W K+ + E K+ I Sbjct: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK---MEIREDPKFLIT 1097 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247 + GV TL I R D TY+ A N G+ + VR Sbjct: 1098 NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138 Score = 40.8 bits (94), Expect = 0.010 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 ++ G + L C V G+P P+V+W KN +I+ F + Q +++ I+ + D+G Sbjct: 1059 VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLNIRRPSPFDAGT 1117 Query: 1416 YSINIKNKYG 1425 Y+ N+ G Sbjct: 1118 YTCRAVNELG 1127 Score = 36.6 bits (83), Expect = 0.18 Identities = 52/259 (20%), Positives = 101/259 (38%), Gaps = 42/259 (16%) Query: 943 WCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELE 1002 W K+ +EI ++ E VG L + D Y V+V D + FV +P Sbjct: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV-- 346 Query: 1003 RLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIH 1062 L+ E + + + E+A E+ ++G W++ + RE S + Sbjct: 347 -LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDG----------VELTREDSFKARY 395 Query: 1063 RIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRK 1122 R K D I ++ E+ G Y V + G+ +++ ++EE + + Sbjct: 396 RFKKDGKRHI--LIFSDVVQEDRGRYQVITNGGQCEAE-----------LIVEEKQLEVL 442 Query: 1123 EFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE---TLPNLE 1179 + + D+T + + V K + ++ KW K+ V T+ ++ Sbjct: 443 QDIA------------DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVG 490 Query: 1180 RGICELLIPKLSKKDHGEY 1198 R +L+I + +D G+Y Sbjct: 491 R-FHKLVIDDVRPEDEGDY 508 Score = 33.9 bits (76), Expect = 1.2 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 1317 DLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEV 1376 DL G A+ + K+AAF +K L + G + L + +PD + Sbjct: 237 DLRGMLKRLKKAKVEVKKSAAFTKK--------LDPAYQVDRGNKIKLMVEI-SDPDLTL 287 Query: 1377 IWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNK 1423 WFKN Q+I+ S + + K + +TI T D Y + +K++ Sbjct: 288 KWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDAAYEVAVKDE 333 Score = 33.9 bits (76), Expect = 1.2 Identities = 40/181 (22%), Positives = 71/181 (39%), Gaps = 10/181 (5%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 F C+ + W K+ E+ +R I VG KL + + ED G Y+ DG Sbjct: 458 FKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV---PDG 514 Query: 990 VSSSFVLDPEELERLMALSNEIKNPTIPL-----KSELAYEIFDKGRVRFWLQAEHLSPD 1044 + S LE + + + P I L SE A + ++R + P Sbjct: 515 YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPP 574 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104 + + EV + R + +K V++ E+EG YT+++ + + +S+ Sbjct: 575 VA--TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632 Query: 1105 L 1105 L Sbjct: 633 L 633 Score = 31.6 bits (70), Expect = 5.9 Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSM-TIKGVTSEDSGKYS 1417 G+ LNL G P P+V+W K + S V V + + ++ ++ DSG+Y Sbjct: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAARSDSGEYE 911 Query: 1418 INIK 1421 ++++ Sbjct: 912 LSVQ 915 >gi|222352127 sidekick 2 [Homo sapiens] Length = 2172 Score = 129 bits (323), Expect = 3e-29 Identities = 182/778 (23%), Positives = 283/778 (36%), Gaps = 110/778 (14%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE--PGKYRIESN 208 S AP I TV + MSV L G P P + W K ++ + P +ES Sbjct: 399 SIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG 458 Query: 209 YGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS 268 +L I+ D TY+ +ATN+ G +A +VV +P + + G S Sbjct: 459 ----SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQAS 514 Query: 269 SMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKW 328 + TH RV R W +D L Sbjct: 515 MVCGVTHDP-------------------------------RVTIRYIWEKDGATLGTESH 543 Query: 329 TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMD 388 ++ + SL S D G YT R++S GG SA L VR + AP P+ Sbjct: 544 PRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQ----LPHAPEHPV- 597 Query: 389 LQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLF 448 R + +TW P SP++ Y ++ E V K V GL Sbjct: 598 ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLV 656 Query: 449 EGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDA 508 RSY FR+ AVN G + S+ ++ V+ L E A Sbjct: 657 PARSYQFRLCAVNDVGKGQFSKDTERVS--------------LPEEPPTA---------- 692 Query: 509 QVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM--YFIEKSVVGSGSWQRVNAQTAVR 566 PP V AS + +++ W+PP ++ ++ Y I + G + T Sbjct: 693 ----PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDAD 748 Query: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKT 626 + DL+ +Y V + N GL S + Q V VP PG V A T Sbjct: 749 VNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVP--PGNVHAEATNST 806 Query: 627 SVVVQWDRPKHEEDLLGYYVDCCVAGTNL--WEPCNHKPI-----------GYNRFVVHG 673 ++ W+ P + +++ G L WEP + + + V G Sbjct: 807 TIRFTWNAPSPQ------FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSG 860 Query: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733 L +Y V G S V+ VP ++ S+ + W+ Sbjct: 861 LKKFTEYFTSVLCFTTPGDGPRSTPQ---LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE 917 Query: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 P G + GY + E + N + P+ V GLT + Y ++AA+ G Sbjct: 918 PGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 976 Query: 794 GEPSDPSEHFKCEAWTMPE-PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFR 852 G+ S + + PE PGP +L + S+ + ++ P Y G + +S + V+ + Sbjct: 977 GQVSAST----ISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDGKTSISRWLVEAQ 1031 Query: 853 EEDAGE---WITVNQTTTAN--RYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 GE W+ ++Q + R ++V DL Y FR+R VN G PS S + Sbjct: 1032 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKI 1089 Score = 109 bits (273), Expect = 2e-23 Identities = 138/582 (23%), Positives = 218/582 (37%), Gaps = 105/582 (18%) Query: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 PG PM + + V + W+PP + R T N +Y Sbjct: 1301 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQY 1360 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 TGL Y+FR+ A G GE A+ Sbjct: 1361 TATGLKPESVYLFRITAQTRKGW---------------------------GEAAEALVVT 1393 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF-IEKSVVGSGSWQRVNA 561 + D P V ++ V+LSWEP + G P+ Y+ I+ + SG W +A Sbjct: 1394 TEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQTRELPSGRWALHSA 1452 Query: 562 QTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGR---- 617 + + + V L SY FRV + N G SE SE +++ +T + +AP Sbjct: 1453 SVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE-----ESESLTTLQAAPDEAPTI 1507 Query: 618 VLASRNTKTSVVVQWDRPKHEE---DLLGY---YVDCCVAG------------------- 652 + + +T TSV+++W P ++ LLG+ Y + G Sbjct: 1508 LSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAEL 1567 Query: 653 TNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS 712 T+++ N ++ + L +Y R+ NAVG +S +V +A T + Sbjct: 1568 TSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT--A 1625 Query: 713 HPYGITLLNCDGHSMTLGWKVPKF-SGGSPILGYYLDKREVHHKNWHE-VNSSPSKPTIL 770 P + + + + W+ P S I GY + E N E V + + Sbjct: 1626 APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSV 1685 Query: 771 TVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLV 830 + LT + Y +AA N AG G S P++ +A P + F E+ TS+ Sbjct: 1686 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQA----APSAPSSVKFSELTTTSVN 1741 Query: 831 MLWKAP------------VYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQ 878 + W+AP VY SPV G + +TV+ + +LKV DL Sbjct: 1742 VSWEAPQFPNGILEGYRLVYEPCSPVDG---------VSKIVTVDVKGNSPLWLKVKDLA 1792 Query: 879 QGKTYVFRVRA--------VNAN-----GVGKPSDTSEPVLV 907 +G TY FR+RA + AN G G P P++V Sbjct: 1793 EGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIV 1834 Score = 102 bits (253), Expect = 4e-21 Identities = 173/746 (23%), Positives = 271/746 (36%), Gaps = 122/746 (16%) Query: 178 QGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQ 237 +G P P + WYKD +++ + + ++R ++ G L+I+ DDT + A NA G+ Sbjct: 333 KGVPPPSITWYKDAAVV-EVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAGE 388 Query: 238 VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTL 297 V T+ + V P + G PL S + +G +V L Sbjct: 389 VQTSTYLAVTSI----APNITRG-----PLDSTV------------------IDGMSVVL 421 Query: 298 KCTMLVTPDLKRVQPRAEWYRDD-VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLR 356 C P +P W + + +L S F SL S H D G YT Sbjct: 422 ACETSGAP-----RPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476 Query: 357 IVSRGGVSDHSAFLFVRDADPLVTGAP-------GAPMDLQC---HDANRDYVIVTWKPP 406 + GV + SA L V A +T P G + C HD R + W+ Sbjct: 477 ATNSRGVDEASADLVVW-ARTRITKPPQDQSVIKGTQASMVCGVTHDP-RVTIRYIWEKD 534 Query: 407 NTT--TESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAG 464 T TES +DR + D C+ G + RS RVR + Sbjct: 535 GATLGTESHPR-IRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQL---- 589 Query: 465 ISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISR 524 P VA L ++ R + Sbjct: 590 ---PHAPEHPVATLSTVERRAIN------------------------------------- 609 Query: 525 NYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFR 584 L+W P G PL+ +I + + W + A ++ V L+ +SY FR Sbjct: 610 ----LTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664 Query: 585 VLSANRHGLSEPSEITSPIQAQDVTVVPSAPGR-VLASRNTKTSVVVQWDRP--KHEEDL 641 + + N G + S+ T + + P+AP + V+AS T S+++QW P H+ + Sbjct: 665 LCAVNDVGKGQFSKDTERVSLPEEP--PTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722 Query: 642 L-GYYVDCCVAGTNL-WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQES 699 L GY + C+AG + ++ N N ++ L Y V A N+ G+ S + Sbjct: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782 Query: 700 DVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHE 759 +Q TVP N T P+F G GY L E + E Sbjct: 783 TEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN-QGYKLIAWEPEQE--EE 839 Query: 760 VNSSPSKPT------ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEP 813 V ++P + V GL + + Y + G G S P E P Sbjct: 840 VTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHE----DVP 895 Query: 814 GPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLK 873 GP L+F E+ DTSL + W+ P + ++GY + + E + + + Sbjct: 896 GPVGHLSFSEILDTSLKVSWQEP-GEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYR 954 Query: 874 VSDLQQGKTYVFRVRAVNANGVGKPS 899 V+ L TY V A+ + G G+ S Sbjct: 955 VTGLTALTTYTIEVAAMTSKGQGQVS 980 Score = 88.6 bits (218), Expect = 4e-17 Identities = 110/436 (25%), Positives = 178/436 (40%), Gaps = 45/436 (10%) Query: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPR 569 VPGPP G+ E+ V L W+PP L Y I + + + A + + Sbjct: 1300 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQ 1359 Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSE-ITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628 Y L Y+FR+ + R G E +E + + +D PS P V SV Sbjct: 1360 YTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRP-MVQQEDVRARSV 1418 Query: 629 VVQWDRPKHEEDLLGYY-VDCCVAGTNLWEPCNHKPIGYN--RFVVHGLTTGEQYIFRVK 685 ++ W+ + YY + + W + + +N F+V L Y FRVK Sbjct: 1419 LLSWEPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNASSFIVDRLKPFTSYKFRVK 1477 Query: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMT---LGWKVP---KFSGG 739 A N +G SE S+ES+ + A + T+L+ H+ T + W+ P K +G Sbjct: 1478 ATNDIGDSEFSEESESLTTLQA----APDEAPTILSVTPHTTTSVLIRWQPPAEDKING- 1532 Query: 740 SPILGYYLDKREVHHK---------------NWHEVNS-----SPSKPTI--LTVDGLTE 777 +LG+ + RE+ ++ W E+ S + S+P++ +D L + Sbjct: 1533 -ILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNK 1591 Query: 778 GSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK-AP 836 YE +++ N G G S P E F EA +P P ++ T L + W+ P Sbjct: 1592 HRRYEIRMSVYNAVGEGPSSPPQEVFVGEA--VPTAAPR-NVVVHGATATQLDVTWEPPP 1648 Query: 837 VYSGSSPVSGYFVDFREEDAGEWI-TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 + S + + GY + F E G V A +K+ +L Y+ V A NA G Sbjct: 1649 LDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGD 1708 Query: 896 GKPSDTSEPVLVEARP 911 G S ++ +A P Sbjct: 1709 GPRSTPTQGQTQQAAP 1724 Score = 87.4 bits (215), Expect = 9e-17 Identities = 125/518 (24%), Positives = 198/518 (38%), Gaps = 60/518 (11%) Query: 401 VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 V+W+ P + GY + E N + P +Y VTGL +Y V A+ Sbjct: 913 VSWQEPGEKN-GILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAM 971 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 S G + S S + + P ++PGPPT + S Sbjct: 972 TSKGQGQVS-ASTISSGVPP----------------------------ELPGPPTNLGIS 1002 Query: 521 EISRNYVVLSWEPPTPRGKDPLMYFI---EKSVVGSG-SWQRVNAQTAVRSPR-YAVFDL 575 I V L + P GK + ++ + VVG G W ++ + R V DL Sbjct: 1003 NIGPRSVTLQFRPGYD-GKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDL 1061 Query: 576 MEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW-DR 634 Y FR+ N G S PS+ + IQ AP V ++TS+ ++W Sbjct: 1062 NPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAP-PDMAPANVSLRTASETSLWLRWMPL 1120 Query: 635 PKHE----EDLLGYYVDCCVA---GTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAV 687 P+ E + +GY + + G L + + + L +Y +V+A Sbjct: 1121 PEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV--ERDYTIEDLEEWTEYRVQVQAF 1178 Query: 688 NAVGMSENSQESDVIKVQAALTVPSH-PYGITLLNCDGHSMTLGW-KVPKFSGGSPILGY 745 NA+G SQ + + +VPS P ++ L SM + W +VP+ +LGY Sbjct: 1179 NAIGSGPWSQ---TVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGY 1235 Query: 746 ---YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEH 802 Y +K + V + S+ LT GL + LYE ++ A G G PS P Sbjct: 1236 KVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQVLAFTRIGDGSPSHPP-- 1291 Query: 803 FKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITV 862 E PGP + F EVR TS+ ++W+ P ++ TV Sbjct: 1292 -ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATV 1350 Query: 863 NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 + R + L+ Y+FR+ A G G+ ++ Sbjct: 1351 EVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1388 Score = 83.2 bits (204), Expect = 2e-15 Identities = 144/597 (24%), Positives = 223/597 (37%), Gaps = 87/597 (14%) Query: 350 EGLYTLRIVS--RGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPN 407 E +Y RI + R G + + L V P PM +Q D V+++W+P + Sbjct: 1368 ESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVLLSWEPGS 1426 Query: 408 TTTESPVMGYFVDRCEVGTNNWVQCNDAPVK--ICKYPVTGLFEGRSYIFRVRAVNSAGI 465 SPV Y + E+ + W + A V + V L SY FRV+A N G Sbjct: 1427 DGL-SPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1484 Query: 466 SRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 S S S++ L LQA E PT + + + Sbjct: 1485 SEFSEESES--------LTTLQAAPDEA--------------------PTILSVTPHTTT 1516 Query: 526 YVVLSWEPPTPRGKDPLMY----------------FIEKSVVGSGS-WQRVNAQTAVRS- 567 V++ W+PP + ++ F + + G+ W + + ++R+ Sbjct: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576 Query: 568 -----PRYAVFDLMEGKSYVFR--VLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 +Y + +L + + Y R V +A G S P + +A V +AP V+ Sbjct: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEA----VPTAAPRNVVV 1632 Query: 621 SRNTKTSVVVQWDRPKHEE---DLLGYYVDCCVAGT-NLWEPCNHKPIGYNRFVVHGLTT 676 T T + V W+ P + D+ GY + A NL E + N + LT Sbjct: 1633 HGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTG 1692 Query: 677 GEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKF 736 Y+ V A NA G S + QAA PS P + S+ + W+ P+F Sbjct: 1693 YTAYMVSVAAFNAAGDGPRSTPTQGQTQQAA---PSAPSSVKFSELTTTSVNVSWEAPQF 1749 Query: 737 SGGSPILGYYLDKREVHHKNWHE----VNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792 G + GY L + V+ + P L V L EG Y F+I A Sbjct: 1750 PNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTY 1808 Query: 793 IGEPSDPSEHFKCEAWTMPEPG-PAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF 851 E + T P G P VR +S + + + G P++ Y ++ Sbjct: 1809 GPE-------IEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEA 1861 Query: 852 REEDAGEW---ITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 R D G W I ++ + L+ G +Y FRV AVN G G PS S+ V Sbjct: 1862 RPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSV 1918 Score = 47.4 bits (111), Expect = 1e-04 Identities = 83/360 (23%), Positives = 133/360 (36%), Gaps = 58/360 (16%) Query: 362 GVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTES-PVMGYFVD 420 G S +FV +A P AP ++ H A + VTW+PP +++ + GY + Sbjct: 1608 GPSSPPQEVFVGEAVPTA-----APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIY 1662 Query: 421 RCEVGTNNWVQ------CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDA 474 E N + + VK+ +TG +Y+ V A N+AG S + Sbjct: 1663 FWEAQRGNLTERVKTLFLAENSVKLKN--LTGY---TAYMVSVAAFNAAGDGPRSTPT-- 1715 Query: 475 VAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPP 534 +G+ + A P P+ V SE++ V +SWE P Sbjct: 1716 -----------------QGQTQQA-----------APSAPSSVKFSELTTTSVNVSWEAP 1747 Query: 535 T-PRG-KDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYA-VFDLMEGKSYVFRVLSANRH 591 P G + E G + V SP + V DL EG +Y FR+ + Sbjct: 1748 QFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-- 1805 Query: 592 GLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDR-PKHEEDLLGYYVDCCV 650 + EI + + P PG + R + +++ + W + + Y ++ Sbjct: 1806 -FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYS-SAIAIHWSSGDPGKGPITRYVIEARP 1863 Query: 651 AGTNLWEPCNH---KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707 + LW+ K + F + L G Y FRV AVN G S S + Q A Sbjct: 1864 SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKA 1923 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 1/94 (1%) Query: 820 TFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQ 879 T V ++ + W P + G+SP+ Y ++ E +A + + + V L Sbjct: 599 TLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVP 657 Query: 880 GKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGT 913 ++Y FR+ AVN G G+ S +E V + P T Sbjct: 658 ARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPT 691 Score = 35.0 bits (79), Expect = 0.53 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 1372 PDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKY---SINIKNKYGGEK 1428 P P+V WF++ + I S ++ +E ++ I + D+G+Y ++N KN Sbjct: 141 PQPQVTWFRDGRKIPPSSRIAITLEN----TLVILSTVAPDAGRYYVQAVNDKNGDNKTS 196 Query: 1429 IDVTVSVYKHGEKIPDMAPPQQAKPK 1454 +T++V G +AP PK Sbjct: 197 QPITLTVENVGGPADPIAPTIIIPPK 222 Score = 32.3 bits (72), Expect = 3.4 Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413 +T K +++ C G P P + W+K+ +++ + + Q + I G+ +D+ Sbjct: 318 ITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEK--LTRFRQRNDGGLQISGLVPDDT 375 Query: 1414 GKYSINIKNKYGGEKIDVTVSVY 1436 G + +N G +V S Y Sbjct: 376 GMFQCFARNAAG----EVQTSTY 394 >gi|148596957 myosin binding protein C, cardiac [Homo sapiens] Length = 1274 Score = 126 bits (317), Expect = 1e-28 Identities = 91/326 (27%), Positives = 142/326 (43%), Gaps = 24/326 (7%) Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMT 728 F V G ++ ++ V N VG E V + VP P + N S T Sbjct: 736 FTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCT 789 Query: 729 LGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAV 788 + W+ P + GG PILGY L++++ W +N + + EG +YE ++ AV Sbjct: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAV 849 Query: 789 NLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848 N G+ PS S+ F + P L +V DT++ + W+ P G+ + GY Sbjct: 850 NAIGMSRPSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905 Query: 849 VDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE 908 V++ E EW+ Q T + + V DL G +FRVRA N G G P T+EPV V+ Sbjct: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965 Query: 909 ----------ARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958 R + I V E N+ + F + Q TW K + ++ +E I Sbjct: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF---QGKPRPQVTWTKEGQPLAGEE-VSI 1021 Query: 959 ETVGDHSKLYLKNPDKEDLGTYSVSV 984 + L+++ + GTY V+V Sbjct: 1022 RNSPTDTILFIRAARRVHSGTYQVTV 1047 Score = 109 bits (273), Expect = 2e-23 Identities = 127/553 (22%), Positives = 212/553 (38%), Gaps = 86/553 (15%) Query: 315 EWYRDDVLLKESKW-TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373 EW D LL E++ ++ + ++ + K+DEG+YT+ + + V + L V+ Sbjct: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV--KNPVGEDQVNLTVK 767 Query: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433 D V AP AP + + D V W+PP P++GY ++R + + W++ N Sbjct: 768 VID--VPDAPAAP---KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822 Query: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493 ++ + + EG Y RV AVN+ G+SRPS S + P Sbjct: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP------------- 869 Query: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVG 552 P PT + ++S V L W PP G L Y +E G Sbjct: 870 -----------------PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912 Query: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612 W Q V DL G +FRV + N G P T P+ Q++ P Sbjct: 913 CSEWVAA-LQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672 R+ R+ + ++ + P NL P KP + Sbjct: 972 ----RLQLPRHLRQTIQKKVGEP-----------------VNLLIPFQGKPRPQVTWTKE 1010 Query: 673 GL-TTGEQYIFR---------VKAVNAVGMS--------ENSQESDVIKVQAALTVPSHP 714 G GE+ R ++A V EN ++ + +Q + PS P Sbjct: 1011 GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ-VVDKPSPP 1069 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774 + + + G ++ L WK P+ G + + GY + K + W V + T V Sbjct: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPE 1128 Query: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834 L G+ Y F++ + N+ G + + ++ E +P PG Y+ + D S + Sbjct: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTK----EPVFIPRPGITYEPPNYKALDFSEAPSFT 1184 Query: 835 APVYSGSSPVSGY 847 P+ + S ++GY Sbjct: 1185 QPLVN-RSVIAGY 1196 Score = 95.1 bits (235), Expect = 4e-19 Identities = 119/525 (22%), Positives = 198/525 (37%), Gaps = 80/525 (15%) Query: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSP 568 VP P S + + + WEPP G P++ Y +E+ S W R+N ++ Sbjct: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQEL 829 Query: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628 + ++EG Y RV + N G+S PS + P PS P + + T+V Sbjct: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVEDVSDTTV 886 Query: 629 VVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686 ++W P+ L GY V+ C G + W + +V L TG + +FRV+A Sbjct: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRA 946 Query: 687 VNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTL-----GWKVPKF 736 N G ++ + VQ L +P H T+ G + L G P+ Sbjct: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH-LRQTIQKKVGEPVNLLIPFQGKPRPQV 1005 Query: 737 S---GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL--TEGSLYEFKIAAVNLA 791 + G P+ G EV + +SP+ TIL + Y+ + N+ Sbjct: 1006 TWTKEGQPLAG-----EEV------SIRNSPT-DTILFIRAARRVHSGTYQVTVRIENM- 1052 Query: 792 GIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF 851 + + +P P DL + ++ + WK P G++ + GY V Sbjct: 1053 --------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104 Query: 852 REEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG-KPSDTSEPVLVEAR 910 ++ EW TV + + V +L G Y FRV + N G + + T EPV + R Sbjct: 1105 ADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFI-PR 1162 Query: 911 PGTKEISAGVDEQGNIYLGFDCQEMTDASQ--------------------------FTWC 944 P G+ + Y D E +Q +W Sbjct: 1163 P-------GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215 Query: 945 KSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989 K+ ++ +D RF++ + L ++ P D G Y ++ G Sbjct: 1216 KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260 Score = 50.4 bits (119), Expect = 1e-05 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 36/136 (26%) Query: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKN-------------------------- 1381 G +PD + ++ G L L + G+P P VIW K Sbjct: 653 GRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWV 712 Query: 1382 -DQDIQLSEHFSVKVEQAKYVSM-TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHG 1439 D+ + V+VE K S+ T++G ED G Y++ +KN G +++++TV V Sbjct: 713 FDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI--- 769 Query: 1440 EKIPDMAPPQQAKPKL 1455 +PD AP A PK+ Sbjct: 770 -DVPD-AP---AAPKI 780 Score = 49.7 bits (117), Expect = 2e-05 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210 S AP L + +V + LC V+G P P + W+K+G E ++R+ S G Sbjct: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG---LDLGEDARFRMFSKQG 1234 Query: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247 V TLEI + D Y ATN G+ + VR Sbjct: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271 Score = 38.9 bits (89), Expect = 0.037 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 +++ G T L C V G+P P++ WFKN D+ F + +Q +++ I+ D G Sbjct: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG-VLTLEIRKPCPFDGG 1249 Query: 1415 KYSINIKNKYGGEKIDVTVSV 1435 Y N G + + + V Sbjct: 1250 IYVCRATNLQGEARCECRLEV 1270 Score = 34.3 bits (77), Expect = 0.91 Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 16/146 (10%) Query: 930 FDCQEMTDASQFTWCKSYEEISDDERFK--IETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987 F+C+ + +Q W K E++ +E FK + G L + ED G Y++ S Sbjct: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532 Query: 988 DGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAY--EIFDKGRVRFWLQ-AEHLSPD 1044 ++ V E+ + + I + + K + + E+ D+ WL+ + L PD Sbjct: 533 QALAELIV-----QEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587 Query: 1045 ASYRFIINDREVSDSEIHRIKCDKAT 1070 + + R +H++ D T Sbjct: 588 SRIKVSHIGR------VHKLTIDDVT 607 Score = 33.9 bits (76), Expect = 1.2 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 25/156 (16%) Query: 1282 SEEMAW--LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339 +EE W L+ P+E ++ + + + D + +R L G DE K+ AF Sbjct: 317 AEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKR---LKGMRRDEK-------KSTAFQ 366 Query: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 +K L + +G + LT + + D EV W KN Q+IQ+S + Sbjct: 367 KK--------LEPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGA 417 Query: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++TI + D Y + GGEK + V Sbjct: 418 KRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449 >gi|46049119 myosin binding protein C, slow type isoform 3 [Homo sapiens] Length = 1141 Score = 125 bits (314), Expect = 3e-28 Identities = 217/1002 (21%), Positives = 360/1002 (35%), Gaps = 199/1002 (19%) Query: 64 GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120 G T R KR+ EE+++ + + L AY K R RF+ ELA + +V ++ Sbjct: 230 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 289 Query: 121 QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161 Q KY + QM +D A + E R P I+V +L Sbjct: 290 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 349 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221 T + V+L V V +W+K+G I + +YRI H L I A Sbjct: 350 DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 407 Query: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281 D A YS + T GQ S +V ++ PL + P T V Sbjct: 408 ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 446 Query: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341 G+ + LKC ++ P +W ++ + ++ES K+ L Sbjct: 447 ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 489 Query: 342 FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393 ++ +DEG Y + + ++ V D + DAD VT G + L+ Sbjct: 490 IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 549 Query: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453 + PP + T ++ + + I + +G Sbjct: 550 SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 595 Query: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513 ++ + N AG E I + D P P Sbjct: 596 VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 622 Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P +E+ ++ +++WEPP G P++ YFIE+ S W R+N + + Sbjct: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 681 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632 ++EG +Y R+ + N G+S+PS + P VT S P + T T+V ++W Sbjct: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 738 Query: 633 DRPKH--EEDLLGYYVDCCVAGTNL------------------WEPCNHKPIGYNRFVVH 672 P H L GY ++ C G+ W N I +F + Sbjct: 739 RPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT 798 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSM 727 GL T + RVKAVNA G SE S I V+ + +P H T + G ++ Sbjct: 799 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAV 857 Query: 728 TLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAA 787 L +P P L + D E+ + NS + + Y+ ++ Sbjct: 858 NL--VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 915 Query: 788 VNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGY 847 E + + PGP + +V ++ + W P G++ ++GY Sbjct: 916 DKFV---------ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966 Query: 848 FVDFREEDAGEWITVNQ---TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904 + ++ + EW TV + T+A +++L G Y FRV + N G+ + + ++ Sbjct: 967 TIQKADKKSMEWFTVIEHYHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKE 1022 Query: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQ------------------------ 940 V AR G + +Y FD E +Q Sbjct: 1023 SAVIARDGK-------IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075 Query: 941 --FTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTY 980 TW K+ I DD R+++ + L ++ P D GTY Sbjct: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117 Score = 110 bits (274), Expect = 1e-23 Identities = 130/565 (23%), Positives = 220/565 (38%), Gaps = 72/565 (12%) Query: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740 ++ + N G + S IKV+ + P P T+ + W+ P + GGS Sbjct: 596 VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649 Query: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 PILGY++++++ W +N K T + EG YE +I AVN GI +PS PS Sbjct: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709 Query: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF--------R 852 F A T P P LT V DT++ M W+ P + G++ + GY +++ + Sbjct: 710 RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765 Query: 853 EED----------AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 + D A +WI N+ ++ L RV+AVNA G +P S Sbjct: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825 Query: 903 EPVLVE----------ARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952 +P+LV+ R + V E N+ + F + + TW K EI D Sbjct: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-D 881 Query: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012 + I + ++++ ++ G Y + V D + +D + ++R Sbjct: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------P 932 Query: 1013 NPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDK 1068 P +K E +++ + W + A + I + E I Sbjct: 933 GPPQIVKIE---DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989 Query: 1069 ATGIIEMVMDR---FSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEF 1124 AT I E+V+ F + +E + K + + G +K V E+ +F Sbjct: 990 AT-ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048 Query: 1125 LRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGI 1182 + + ++ T C VR N K + W+K+ V + + +G+ Sbjct: 1049 FTQPLVNTYAIAGYNATLNCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGV 1101 Query: 1183 CELLIPKLSKKDHGEYKATLKDDRG 1207 C L I K S D G Y +D G Sbjct: 1102 CTLEIRKPSPYDGGTYCCKAVNDLG 1126 Score = 45.4 bits (106), Expect = 4e-04 Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%) Query: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059 L+RL + E K K + AY++ GRVRF + E P ++ N +E+ S Sbjct: 238 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295 Query: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119 + + I+ ++ + ++ Y V D K ++ Sbjct: 296 TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 335 Query: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177 F+R+ + L D T C R+ + ++ + KW K+ E +P Sbjct: 336 ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 386 Query: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231 +E L+I +K D EY S++ G+ S Sbjct: 387 SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 426 Query: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286 PLK+L T + + L C ++ + W + S+ +++ + Sbjct: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 486 Query: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346 L I +D+G Y F D + +L D A Sbjct: 487 KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 531 Query: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403 + VT++ G L L + G P P+ +W + D+ I S ++ Y ++ Sbjct: 532 ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 584 Query: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447 I +DSG Y IN+KN+ G + V V + P +AP Sbjct: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 626 Score = 40.0 bits (92), Expect = 0.017 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235 +V+G P P + W K+ I + +YR+ SN GV TLEI + D TY A N Sbjct: 1069 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125 Query: 236 GQVSTNAAVVVR 247 G V + V+ Sbjct: 1126 GTVEIECKLEVK 1137 Score = 35.4 bits (80), Expect = 0.41 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G L C+V GNP P++ W KN I + + Q ++ I+ + D G Y Sbjct: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1119 Query: 1419 NIKNKYGGEKIDVTVSV 1435 N G +I+ + V Sbjct: 1120 KAVNDLGTVEIECKLEV 1136 Score = 31.2 bits (69), Expect = 7.7 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 G+ +NL G P PE+ W K+ +I ++ +++ + + + I+ SGKY + Sbjct: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 911 Query: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452 +K E + + + I PPQ K Sbjct: 912 QVKVDKFVETASIDIQI------IDRPGPPQIVK 939 >gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform ROBO2a [Homo sapiens] Length = 1394 Score = 110 bits (276), Expect = 8e-24 Identities = 163/696 (23%), Positives = 261/696 (37%), Gaps = 128/696 (18%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 E + P L R + V E +V+ VQG P P V+W KD + + + G+Y I+ Sbjct: 234 ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPR----GRYDIK 289 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +Y TL I + D TY +A N G++ +A + VR Sbjct: 290 DDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA------------------ 328 Query: 267 LSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKES 326 QF+ + +G TVT C P QP W KE Sbjct: 329 ----------PPQFVVRPRDQIVAQGRTVTFPCETKGNP-----QPAVFWQ------KEG 367 Query: 327 KWTKMFFGEGQ-----------ASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA 375 +F + Q L+ +++ + D G Y + ++ G A L V D Sbjct: 368 SQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD- 426 Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 ++T P P+ LQ P N T V G + +C+ + Sbjct: 427 --VLTDRP-PPIILQ-------------GPANQTLA--VDGTALLKCKATGD-------- 460 Query: 436 PVKICKYPVTGL-FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGE 494 P+ + + G F GR ++ + I R+SD A GE Sbjct: 461 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKN-LRISDT-------GTYTCVATSSSGE 512 Query: 495 KEIAIYQDDLEGDAQV---------PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 + D E A + PGPP+ +++++N V LSW+P TP Y Sbjct: 513 TSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYI 572 Query: 546 IEK-SVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ 604 IE S S SWQ V V++ Y V L Y+F V + N GLS+PS ++ P++ Sbjct: 573 IEAFSQSVSNSWQTV--ANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVR 630 Query: 605 AQDVT---------VVPSAPGRVLASRN-----TKTSVVVQWDRPKHEEDLLGYYV---- 646 QD++ V G VL + T T+V V W + + + GY V Sbjct: 631 TQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQ 690 Query: 647 DCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 + T+ W+ + K V+ L G Y +V+ +S+ V + Sbjct: 691 TSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEE 750 Query: 707 ALTVPSHPYGITLLNCDGH---SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 A + P P +T+L + S+++ W P + I+ Y + +H + Sbjct: 751 APSAP--PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTV 808 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + GL G Y ++AA AG+G S+P Sbjct: 809 DAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 844 Score = 51.2 bits (121), Expect = 7e-06 Identities = 51/227 (22%), Positives = 91/227 (40%), Gaps = 18/227 (7%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTI 769 +P P + + +S+TL W+ P G P Y ++ N + ++ K T+ Sbjct: 537 LPGPPSKPQVTDVTKNSVTLSWQ-PGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTL 595 Query: 770 LTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSL 829 TV GL ++Y F + A+N G+ +PS S+ + + + P G + E+ D L Sbjct: 596 YTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDV-L 654 Query: 830 VMLWKAPVYSGSSP------------VSGYFVDFRE----EDAGEWITVNQTTTANRYLK 873 V L V + ++ + GY V +R+ + W ++ R Sbjct: 655 VRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAV 714 Query: 874 VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV 920 + +L++G TY +VR G S++ E P S V Sbjct: 715 LVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTV 761 Score = 49.3 bits (116), Expect = 3e-05 Identities = 71/314 (22%), Positives = 119/314 (37%), Gaps = 60/314 (19%) Query: 1148 LVCKVANTKKETVFKWLKDDVLYETET---------LPNLERGICELLIPKLSKKDHGEY 1198 L CK T+ +W KD ET+ LP+ ++ + SK D G Y Sbjct: 66 LNCKAEGRPTPTI-EWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSY 124 Query: 1199 KATLKDDRGQDVS---ILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKY 1255 ++ G+ VS LE+A + DD + V + P + C P + + + Sbjct: 125 VCVARNYLGEAVSRNASLEVA-LLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYW 183 Query: 1256 FTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRS 1315 D+++++ E + I G + L I + D G YT Sbjct: 184 KKDKVRID--------DKEERISIRGGK----LMISNTRKSDAGMYTCV----------G 221 Query: 1316 LDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375 ++ G+ D AE F+ F + P ++E + + C V G+P P Sbjct: 222 TNMVGER-DSDPAELTVFERPTFLRR---------PINQVVLEEEAVEFRCQVQGDPQPT 271 Query: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 V W K+D D+ + +K + ++ IK S D G Y +N+ G + T++V Sbjct: 272 VRWKKDDADLPRG-RYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326 Query: 1436 YKHGEKIPDMAPPQ 1449 APPQ Sbjct: 327 ---------RAPPQ 331 Score = 40.0 bits (92), Expect = 0.017 Identities = 48/182 (26%), Positives = 72/182 (39%), Gaps = 39/182 (21%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYKDG + +P +R+ G + L I R D +Y VA N Sbjct: 71 EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARN 130 Query: 234 AHGQ-VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREG 292 G+ VS NA++ V R D FR P + +++ G Sbjct: 131 YLGEAVSRNASLEVALLRDD---FRQ--NPTDVVVAA----------------------G 163 Query: 293 ETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGL 352 E L+C P +P W +D V + + + G L S+ K D G+ Sbjct: 164 EPAILEC----QPPRGHPEPTIYWKKDKVRIDDKEERISIRG---GKLMISNTRKSDAGM 216 Query: 353 YT 354 YT Sbjct: 217 YT 218 Score = 31.6 bits (70), Expect = 5.9 Identities = 20/91 (21%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE-----HFSVKVEQAKYVSMTI 1405 P V + +G+ L C G P P + W+K+ + ++ + H + + + + Sbjct: 53 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 112 Query: 1406 KGVTSE-DSGKYSINIKNKYGGEKIDVTVSV 1435 G S+ D G Y + + Y GE + S+ Sbjct: 113 HGRRSKPDEGSY-VCVARNYLGEAVSRNASL 142 Score = 31.2 bits (69), Expect = 7.7 Identities = 18/65 (27%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS----MTIKGVTSE 1411 + +G+T+ C GNP P V W K L + + VS +TI + Sbjct: 341 VAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS 400 Query: 1412 DSGKY 1416 D+G Y Sbjct: 401 DAGYY 405 >gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform ROBO2b [Homo sapiens] Length = 1378 Score = 110 bits (276), Expect = 8e-24 Identities = 163/696 (23%), Positives = 261/696 (37%), Gaps = 128/696 (18%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 E + P L R + V E +V+ VQG P P V+W KD + + + G+Y I+ Sbjct: 218 ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPR----GRYDIK 273 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 +Y TL I + D TY +A N G++ +A + VR Sbjct: 274 DDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA------------------ 312 Query: 267 LSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKES 326 QF+ + +G TVT C P QP W KE Sbjct: 313 ----------PPQFVVRPRDQIVAQGRTVTFPCETKGNP-----QPAVFWQ------KEG 351 Query: 327 KWTKMFFGEGQ-----------ASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDA 375 +F + Q L+ +++ + D G Y + ++ G A L V D Sbjct: 352 SQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD- 410 Query: 376 DPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDA 435 ++T P P+ LQ P N T V G + +C+ + Sbjct: 411 --VLTDRP-PPIILQ-------------GPANQTLA--VDGTALLKCKATGD-------- 444 Query: 436 PVKICKYPVTGL-FEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGE 494 P+ + + G F GR ++ + I R+SD A GE Sbjct: 445 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKN-LRISDT-------GTYTCVATSSSGE 496 Query: 495 KEIAIYQDDLEGDAQV---------PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF 545 + D E A + PGPP+ +++++N V LSW+P TP Y Sbjct: 497 TSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYI 556 Query: 546 IEK-SVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ 604 IE S S SWQ V V++ Y V L Y+F V + N GLS+PS ++ P++ Sbjct: 557 IEAFSQSVSNSWQTV--ANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVR 614 Query: 605 AQDVT---------VVPSAPGRVLASRN-----TKTSVVVQWDRPKHEEDLLGYYV---- 646 QD++ V G VL + T T+V V W + + + GY V Sbjct: 615 TQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQ 674 Query: 647 DCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQA 706 + T+ W+ + K V+ L G Y +V+ +S+ V + Sbjct: 675 TSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEE 734 Query: 707 ALTVPSHPYGITLLNCDGH---SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS 763 A + P P +T+L + S+++ W P + I+ Y + +H + Sbjct: 735 APSAP--PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTV 792 Query: 764 PSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + GL G Y ++AA AG+G S+P Sbjct: 793 DAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 828 Score = 51.2 bits (121), Expect = 7e-06 Identities = 51/227 (22%), Positives = 91/227 (40%), Gaps = 18/227 (7%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTI 769 +P P + + +S+TL W+ P G P Y ++ N + ++ K T+ Sbjct: 521 LPGPPSKPQVTDVTKNSVTLSWQ-PGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTL 579 Query: 770 LTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSL 829 TV GL ++Y F + A+N G+ +PS S+ + + + P G + E+ D L Sbjct: 580 YTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDV-L 638 Query: 830 VMLWKAPVYSGSSP------------VSGYFVDFRE----EDAGEWITVNQTTTANRYLK 873 V L V + ++ + GY V +R+ + W ++ R Sbjct: 639 VRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAV 698 Query: 874 VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV 920 + +L++G TY +VR G S++ E P S V Sbjct: 699 LVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTV 745 Score = 49.3 bits (116), Expect = 3e-05 Identities = 71/314 (22%), Positives = 119/314 (37%), Gaps = 60/314 (19%) Query: 1148 LVCKVANTKKETVFKWLKDDVLYETET---------LPNLERGICELLIPKLSKKDHGEY 1198 L CK T+ +W KD ET+ LP+ ++ + SK D G Y Sbjct: 50 LNCKAEGRPTPTI-EWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSY 108 Query: 1199 KATLKDDRGQDVS---ILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKY 1255 ++ G+ VS LE+A + DD + V + P + C P + + + Sbjct: 109 VCVARNYLGEAVSRNASLEVA-LLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYW 167 Query: 1256 FTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRS 1315 D+++++ E + I G + L I + D G YT Sbjct: 168 KKDKVRID--------DKEERISIRGGK----LMISNTRKSDAGMYTCV----------G 205 Query: 1316 LDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375 ++ G+ D AE F+ F + P ++E + + C V G+P P Sbjct: 206 TNMVGER-DSDPAELTVFERPTFLRR---------PINQVVLEEEAVEFRCQVQGDPQPT 255 Query: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 V W K+D D+ + +K + ++ IK S D G Y +N+ G + T++V Sbjct: 256 VRWKKDDADLPRG-RYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310 Query: 1436 YKHGEKIPDMAPPQ 1449 APPQ Sbjct: 311 ---------RAPPQ 315 Score = 40.0 bits (92), Expect = 0.017 Identities = 48/182 (26%), Positives = 72/182 (39%), Gaps = 39/182 (21%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYKDG + +P +R+ G + L I R D +Y VA N Sbjct: 55 EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARN 114 Query: 234 AHGQ-VSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREG 292 G+ VS NA++ V R D FR P + +++ G Sbjct: 115 YLGEAVSRNASLEVALLRDD---FRQ--NPTDVVVAA----------------------G 147 Query: 293 ETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGL 352 E L+C P +P W +D V + + + G L S+ K D G+ Sbjct: 148 EPAILEC----QPPRGHPEPTIYWKKDKVRIDDKEERISIRG---GKLMISNTRKSDAGM 200 Query: 353 YT 354 YT Sbjct: 201 YT 202 Score = 31.6 bits (70), Expect = 5.9 Identities = 20/91 (21%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE-----HFSVKVEQAKYVSMTI 1405 P V + +G+ L C G P P + W+K+ + ++ + H + + + + Sbjct: 37 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 96 Query: 1406 KGVTSE-DSGKYSINIKNKYGGEKIDVTVSV 1435 G S+ D G Y + + Y GE + S+ Sbjct: 97 HGRRSKPDEGSY-VCVARNYLGEAVSRNASL 126 Score = 31.2 bits (69), Expect = 7.7 Identities = 18/65 (27%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVS----MTIKGVTSE 1411 + +G+T+ C GNP P V W K L + + VS +TI + Sbjct: 325 VAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS 384 Query: 1412 DSGKY 1416 D+G Y Sbjct: 385 DAGYY 389 >gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo sapiens] Length = 1386 Score = 107 bits (266), Expect = 1e-22 Identities = 180/785 (22%), Positives = 291/785 (37%), Gaps = 122/785 (15%) Query: 63 LGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQA 122 LG R + V+ D+ +++ ++V A GE + H E V + A Sbjct: 149 LGAAASRNASLEVAVLRDDFRQSPG---NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGA 205 Query: 123 RDKLDKYAI-----QQMMEDKLAWERHTFE--------ERISRAPEILVRLR-------- 161 R K ++ I + MM L + + ER S A E++V R Sbjct: 206 RLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPV 265 Query: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYK-DGSLICQAAEPGKYRIESNYGVHTLEINRAD 220 + V V V+G P P ++W K DG L G+Y I S+ H+L I Sbjct: 266 NQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-----PTGRYEIRSD---HSLWIGHVS 317 Query: 221 FDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQF 280 +D TY+ VA N+ G+ + ++ V H Q Sbjct: 318 AEDEGTYTCVAENSVGRAEASGSLSV----------------------------HVPPQL 349 Query: 281 LEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRD--DVLLKESKW---TKMFFGE 335 + + GE+V +C P P W ++ VLL S+ T F Sbjct: 350 VTQPQDQMAAPGESVAFQCETKGNPP-----PAIFWQKEGSQVLLFPSQSLQPTGRFSVS 404 Query: 336 GQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDAN 395 + L+ + + + D G Y + VS G A L ++ A + G P P+ LQ AN Sbjct: 405 PRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGAS--LDGLP--PVILQ-GPAN 459 Query: 396 RDYVIVT--WKPPNTT-TESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRS 452 + V+ + W P T P + + D W+Q +D K + G Sbjct: 460 QTLVLGSSVWLPCRVTGNPQPSVRWKKD------GQWLQGDDLQFKT-------MANGTL 506 Query: 453 YIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPG 512 YI V+ ++ S ++ S A L+ ++ + D + PG Sbjct: 507 YIANVQEMDMGFYSCVAKSSTGEATWSGW---------LKMREDWGVSPDPPTEPSSPPG 557 Query: 513 PPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572 P+ +EI++N + L+W+P G Y IE +G+ R A V+ + V Sbjct: 558 APSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVAD-GVQLETHTV 616 Query: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAP---------GRVLASRN 623 L Y+F V + GLSEPS ++ P++ QD + PS P G + Sbjct: 617 SGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSS--PSRPVEDPWRGQQGLAEVAVR 674 Query: 624 TKTSVV-------VQWDRPKHEEDLLGYYVDCCVAGTN--LWEPCNHKPIGYNRFVVHGL 674 + +V V W + + G+ V VAG W + + V+ GL Sbjct: 675 LQEPIVLGPRTLQVSWTVDGPVQLVQGFRVSWRVAGPEGGSWTMLDLQSPSQQSTVLRGL 734 Query: 675 TTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVP 734 G Q +V+A G+ S + A + P + L S+T+ W+ P Sbjct: 735 PPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPP 794 Query: 735 KFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIG 794 S + ++ Y + +H S+ + GL G LY +AA AG+G Sbjct: 795 LPSQQNGVITEYQIWCLGNESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVG 854 Query: 795 EPSDP 799 PS P Sbjct: 855 VPSAP 859 Score = 46.6 bits (109), Expect = 2e-04 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 1/93 (1%) Query: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872 PG E+ S+ + WK +G++ S F W TV + Sbjct: 556 PGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHT 615 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 VS LQ Y+F VRAV A G+ +PS SEPV Sbjct: 616 -VSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPV 647 Score = 38.9 bits (89), Expect = 0.037 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 12/91 (13%) Query: 1343 RGRLIGGLPDVV-------TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE-HFSVK 1394 +G + GLP V+ T++ G ++ L C V GNP P V W K+ Q +Q + F Sbjct: 442 KGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTM 501 Query: 1395 VEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425 Y++ V D G YS K+ G Sbjct: 502 ANGTLYIA----NVQEMDMGFYSCVAKSSTG 528 Score = 34.3 bits (77), Expect = 0.91 Identities = 41/198 (20%), Positives = 76/198 (38%), Gaps = 30/198 (15%) Query: 1240 VLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSE-HMRIGGSEEMAWLQICEPTEKDK 1298 V+ E L+C E V+W A++ E + I G + L + + D Sbjct: 176 VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK----LMMSHTLKSDA 231 Query: 1299 GKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIME 1358 G Y + +++G+ + A AE + +F + P ++ Sbjct: 232 GMYVCV----------ASNMAGER-ESAAAEVMVLERPSFLRR---------PVNQVVLA 271 Query: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418 + C V G+P P + W K D ++ + E S+ I V++ED G Y+ Sbjct: 272 DAPVTFLCEVKGDPPPRLRWRKEDGELPTGRY-----EIRSDHSLWIGHVSAEDEGTYTC 326 Query: 1419 NIKNKYGGEKIDVTVSVY 1436 +N G + ++SV+ Sbjct: 327 VAENSVGRAEASGSLSVH 344 >gi|224994173 roundabout 1 isoform d [Homo sapiens] Length = 1551 Score = 101 bits (252), Expect = 5e-21 Identities = 152/698 (21%), Positives = 263/698 (37%), Gaps = 118/698 (16%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 266 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V+ G E P Sbjct: 267 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPP------ 315 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 316 -------------HFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 353 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 354 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 413 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 414 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 454 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 455 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 498 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 558 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 559 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 617 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 674 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 675 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 734 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 735 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 792 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 793 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 582 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 583 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 640 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 641 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 700 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 701 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 760 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 761 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 815 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 816 VAASTGAGSGVKSEPQFIQ 834 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 485 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 486 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 529 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 73 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 131 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 132 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 182 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 183 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 227 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 228 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 273 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 53 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 112 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 113 YLGEAVSHNASLEVAILRDD 132 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 384 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 385 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 419 >gi|224994171 roundabout 1 isoform c [Homo sapiens] Length = 1606 Score = 101 bits (252), Expect = 5e-21 Identities = 152/698 (21%), Positives = 263/698 (37%), Gaps = 118/698 (16%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 266 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V+ G E P Sbjct: 267 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPP------ 315 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 316 -------------HFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 353 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 354 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 413 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 414 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 454 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 455 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 498 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 558 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 559 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 617 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 674 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 675 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 734 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 735 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 792 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 793 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 582 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 583 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 640 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 641 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 700 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 701 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 760 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 761 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 815 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 816 VAASTGAGSGVKSEPQFIQ 834 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 485 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 486 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 529 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 73 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 131 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 132 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 182 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 183 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 227 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 228 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 273 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 53 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 112 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 113 YLGEAVSHNASLEVAILRDD 132 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 384 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 385 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 419 >gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo sapiens] Length = 1562 Score = 101 bits (252), Expect = 5e-21 Identities = 152/698 (21%), Positives = 263/698 (37%), Gaps = 118/698 (16%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 266 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V+ G E P Sbjct: 267 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPP------ 315 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 316 -------------HFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 353 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 354 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 413 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 414 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 454 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 455 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 498 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 558 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 559 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 617 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 674 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 675 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 734 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 735 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 792 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 793 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 582 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 583 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 640 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 641 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 700 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 701 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 760 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 761 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 815 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 816 VAASTGAGSGVKSEPQFIQ 834 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 485 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 486 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 529 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 73 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 131 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 132 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 182 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 183 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 227 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 228 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 273 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 53 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 112 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 113 YLGEAVSHNASLEVAILRDD 132 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 384 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 385 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 419 >gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo sapiens] Length = 1615 Score = 101 bits (252), Expect = 5e-21 Identities = 152/698 (21%), Positives = 263/698 (37%), Gaps = 118/698 (16%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 266 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V+ G E P Sbjct: 267 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPP------ 315 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 316 -------------HFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 353 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 354 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 413 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 414 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 454 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 455 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 498 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 558 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 559 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 617 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 674 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 675 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 734 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 735 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 792 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 793 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 582 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 583 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 640 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 641 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 700 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 701 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 760 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 761 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 815 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 816 VAASTGAGSGVKSEPQFIQ 834 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 485 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 486 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 529 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 73 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 131 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 132 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 182 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 183 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 227 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 228 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 273 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 53 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 112 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 113 YLGEAVSHNASLEVAILRDD 132 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 384 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 385 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 419 >gi|119220552 sidekick 1 [Homo sapiens] Length = 2213 Score = 100 bits (249), Expect = 1e-20 Identities = 136/545 (24%), Positives = 216/545 (39%), Gaps = 77/545 (14%) Query: 382 APGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD-RCEVGTNNWVQCNDAPVKIC 440 APG P+ L + V + W+PP ++GY + R + + + + Sbjct: 1377 APGPPVRLVFPEVRLTSVRIVWQPPEEPN-GIILGYQIAYRLASSSPHTFTTVEVGATVR 1435 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 ++ T L +YIFR+ A G P L+A + EK Sbjct: 1436 QFTATDLAPESAYIFRLSAKTRQGWGEP-----------------LEATVITTEKR---- 1474 Query: 501 QDDLEGDAQVPGPPTG--VHASEISRNYVVLSWEPPTPRGKDPLMYF-IEKSVVGSGSWQ 557 + P PP V +E++ + L W P + G P+ YF ++ + G WQ Sbjct: 1475 --------ERPAPPRELLVPQAEVTARSLRLQWVPGSD-GASPIRYFTMQVRELPRGEWQ 1525 Query: 558 RVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQA-QDVTVVPSAPG 616 ++ + + V L SY R+ + N G S+ S T + QDV P PG Sbjct: 1526 TYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEP--PG 1583 Query: 617 RVLASRNTKTSVVVQWDRPKHEEDLLG-------YYVDC-CVAGTNLWEPCNHKPIGYNR 668 V A+ +T +SV++QW +P +E L G YY + AG+ PI + Sbjct: 1584 SVSATPHTTSSVLIQW-QPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHA 1642 Query: 669 FV--------VHGLTTG-----------EQYIFRVKAVNAVGMSENSQESDVIKVQAALT 709 + V+ +T +Y + A N +G S S +V +AA Sbjct: 1643 ELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPA 1702 Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP-T 768 + +T L +T P+ G+ I GY + E +N E P Sbjct: 1703 MAPQNVQVTPLTASQLEVTWDPPPPESQNGN-IQGYKIYYWEADSQNETEKMKVLFLPEP 1761 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 ++ + LT + Y I+A N AG G SDP + +A PG L F E+ T+ Sbjct: 1762 VVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQA----APGAPSFLAFSEITSTT 1817 Query: 829 LVMLWKAPVYSGSSPVSGYFVDFRE----EDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 L + W P + + + GY V + + + +TV R+LKV DL +G TY Sbjct: 1818 LNVSWGEPA-AANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYF 1876 Query: 885 FRVRA 889 FRV+A Sbjct: 1877 FRVQA 1881 Score = 99.8 bits (247), Expect = 2e-20 Identities = 178/806 (22%), Positives = 298/806 (36%), Gaps = 118/806 (14%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAE-- 199 + HT+ + + AP R TV + M+ L V G P P + W ++ ++ + Sbjct: 468 QTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRI 527 Query: 200 PGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSV 259 P +ES L+I D Y+ A N G ++ +A + V P Sbjct: 528 PRFMLLESG----GLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHP---- 579 Query: 260 GLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRD 319 P H ++ G T TL C P RV R W +D Sbjct: 580 ------------PEDHVVIK------------GTTATLHCGATHDP---RVSLRYVWKKD 612 Query: 320 DVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV 379 +V L S +++ E SL S D G Y+ IVS GG A L V + Sbjct: 613 NVALTPSSTSRIVV-EKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIEL---- 667 Query: 380 TGAPGAPMDLQC--HDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPV 437 P +P +L + ++ V+++W P SP++ Y V+ E + V ++ Sbjct: 668 ---PHSPQNLLVSPNSSHSHAVVLSWVRP-FDGNSPILYYIVELSENNSPWKVHLSNVGP 723 Query: 438 KICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEI 497 ++ V+GL R+Y FRV AVN G + S + + Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRL---------------------- 761 Query: 498 AIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM--YFIEKSVVG-SG 554 + + PP + AS + +++ W+PP + ++ Y + + G G Sbjct: 762 ------MLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPG 815 Query: 555 SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSA 614 +Q+ N T+ V DL+ Y +V + N GL S + Q V P Sbjct: 816 EYQQRNI-TSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAP-- 872 Query: 615 PGRVLASRNTKTSVVVQWDRPKHE--------EDLLGYYVDCCVAGTNLW-EPCNHKPIG 665 P V T++ W+ P + LL + D A T + P H G Sbjct: 873 PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFH---G 929 Query: 666 YNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGH 725 + + L Y V G S V + H +L+ Sbjct: 930 VHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDT--- 986 Query: 726 SMTLGWKVPKFSGGSPILGYYLDKREVHHKN----WHEVNSSPSKPTILTVDGLTEGSLY 781 S+ + W+ P G I GY + EV+ +N H +NS+ + + GL+ + Y Sbjct: 987 SLKVSWQEPLEKNGI-ITGYQI-SWEVYGRNDSRLTHTLNSTTHE---YKIQGLSSLTTY 1041 Query: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPE-PGPAYDLTFCEVRDTSLVMLWKAPVYSG 840 +AAV G G + + + P+ PG +L + S + ++ P Y G Sbjct: 1042 TIDVAAVTAVGTGLVTSST----ISSGVPPDLPGAPSNLVISNISPRSATLQFR-PGYDG 1096 Query: 841 SSPVSGYFVDFRE---EDAGEWITV--NQTTTANRYLKVSDLQQGKTYVFRVRAVNANGV 895 + +S + V+ + D EW+T+ + + L++ +L Y FR++ VN G Sbjct: 1097 KTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGP 1156 Query: 896 GKPSDTSEPV-LVEARPGTKEISAGV 920 S +S + ++A P S V Sbjct: 1157 SPYSPSSRVIQTLQAPPDVAPTSVTV 1182 Score = 78.6 bits (192), Expect = 4e-14 Identities = 111/468 (23%), Positives = 181/468 (38%), Gaps = 43/468 (9%) Query: 353 YTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPM-DLQCHDANRDYVIVTWKPPNTTTE 411 Y LR+ + + D S F +A + PG P + V++ W+PP + Sbjct: 1549 YKLRLKATNDIGD-SDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESL 1607 Query: 412 SPVM-GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSR 470 + ++ GY + E+ + + K K P+ L + + VNS+ S Sbjct: 1608 NGLLQGYRIYYREL---EYEAGSGTEAKTLKNPIA-LHAELTAQSSFKTVNSSSTS---- 1659 Query: 471 VSDAVAALDPLDLRR-----LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRN 525 + L L R + A ++ GE + + G+A P V + ++ + Sbjct: 1660 ---TMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTAS 1716 Query: 526 YVVLSWEPPTPRGKDP-----LMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 + ++W+PP P ++ +Y+ E +V + P + +L Sbjct: 1717 QLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKV---LFLPEPVVRLKNLTSHTK 1773 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED 640 Y+ + + N G S+ P Q + P AP + S T T++ V W P Sbjct: 1774 YLVSISAFNAAGDGPKSD---PQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANG 1830 Query: 641 LL-GYYVD----CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSEN 695 +L GY V V G + + V LT G Y FRV+A + Sbjct: 1831 ILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA-RTITYGPE 1889 Query: 696 SQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHK 755 Q + I A P P + L+ +TL W SG +P GY ++ R Sbjct: 1890 LQAN--ITAGPAEGSPGSPRDV-LVTKSASELTLQW-TEGHSGDTPTTGYVIEARPSDEG 1945 Query: 756 NWHE-VNSSPSKPT--ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800 W V P T L++D L +G YEF++ AVN AG GEPS+PS Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPS 1993 Score = 73.9 bits (180), Expect = 1e-12 Identities = 127/603 (21%), Positives = 226/603 (37%), Gaps = 69/603 (11%) Query: 358 VSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGY 417 V RG S ++ L + + P AP P ++ ++V W+PP T + V+ Sbjct: 749 VGRGQYSAETSRLMLPEEPP---SAP--PKNIVASGRTNQSIMVQWQPPPETEHNGVLRG 803 Query: 418 FVDRCEVG--TNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAV 475 ++ R + + Q N ++ VT L Y +V A N AG+ SR Sbjct: 804 YILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSR----- 858 Query: 476 AALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT 535 A+ L+ + + + A+ ++ + PP + I++ Y +L+W Sbjct: 859 -AVTEYTLQGVPTAPPQNVQTEAVNSTTIQF---LWNPPPQQFINGINQGYKLLAWPADA 914 Query: 536 PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSE 595 P + + V G + +L + +Y VL G Sbjct: 915 PEAVTVVTIAPDFHGVHHGH----------------ITNLKKFTAYFTSVLCFTTPGDGP 958 Query: 596 PSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLL-GYYVDCCVAGTN 654 PS +D P A G + + TS+ V W P + ++ GY + V G N Sbjct: 959 PSTPQLVWTQEDK---PGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRN 1015 Query: 655 LWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHP 714 + + + + GL++ Y V AV AVG + S I +P P Sbjct: 1016 DSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVT--SSTISSGVPPDLPGAP 1073 Query: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREV---HHKNWHEVNSSPSKPT--I 769 + + N S TL ++ P + G + I + ++ + + W + ++P + Sbjct: 1074 SNLVISNISPRSATLQFR-PGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQM 1132 Query: 770 LTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSL 829 L + LT + Y F++ VN+ G P PS P+ P +T +TSL Sbjct: 1133 LEIPNLTPYTHYRFRMKQVNIVG-PSPYSPSSRVIQTLQAPPDVAPT-SVTVRTASETSL 1190 Query: 830 VMLWKAPV----YSGSSPVSGYFVDF-REEDAGEWITVNQTTTANRYLKVSDLQQGKTYV 884 + W P+ Y+G+ GY + + R + + + R + +L++ Y Sbjct: 1191 RLRW-VPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYE 1249 Query: 885 FRVRAVNANGVGK-------------PSDTSEPVLVEARPGTKEI----SAGVDEQGNIY 927 +++A NA G G PS E V EA T+ + S +Q + Sbjct: 1250 LQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLI 1309 Query: 928 LGF 930 LG+ Sbjct: 1310 LGY 1312 Score = 73.6 bits (179), Expect = 1e-12 Identities = 110/464 (23%), Positives = 180/464 (38%), Gaps = 62/464 (13%) Query: 485 RLQAVHLEGEKEIAIYQDDLEGDAQVPG-PPTGVHASEISRNYVVLSWEPPTPRGKDPLM 543 RL+A + G+ + + + + VPG PP V A+ + + V++ W+PP + L+ Sbjct: 1552 RLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLL 1611 Query: 544 -----YFIEKSV-VGSGSWQR-----------VNAQTAVR----SPRYAVFDLMEGKSYV 582 Y+ E GSG+ + + AQ++ + S + +L K Y Sbjct: 1612 QGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYR 1671 Query: 583 FRVLSANRHGLSEPSEITSPIQAQDVTVVPS-APGRVLASRNTKTSVVVQWDRPKHEE-- 639 + + + S ++P++ P+ AP V + T + + V WD P E Sbjct: 1672 RYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQN 1731 Query: 640 -DLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH--GLTTGEQYIFRVKAVNAVGMSENS 696 ++ GY + A + E K + VV LT+ +Y+ + A NA G S Sbjct: 1732 GNIQGYKIYYWEADSQN-ETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKS 1790 Query: 697 QESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGG------------SPILG 744 QAA P P + ++ + W P + G +P+ G Sbjct: 1791 DPQQGRTHQAA---PGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQG 1847 Query: 745 YYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFK 804 NW L V LT+G Y F++ A + E Sbjct: 1848 VSKVVTVEVRGNWQRW---------LKVRDLTKGVTYFFRVQARTITYGPELQANITAGP 1898 Query: 805 CEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW--ITV 862 E PG D+ + + L + W +SG +P +GY ++ R D G W Sbjct: 1899 AEG----SPGSPRDVLVTKSA-SELTLQWTEG-HSGDTPTTGYVIEARPSDEGLWDMFVK 1952 Query: 863 NQTTTANRY-LKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 + +A Y L + L+QG TY FRV AVN G G+PS+ S V Sbjct: 1953 DIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAV 1996 Score = 72.4 bits (176), Expect = 3e-12 Identities = 115/514 (22%), Positives = 191/514 (37%), Gaps = 52/514 (10%) Query: 446 GLFEGRSYIFRVRAVNS---AGISRPSRVSDAV-AALDPLDLRRLQAVHL----EGEKEI 497 GL G +FR + ++ + I R + A+ A L L LQ + G Sbjct: 1307 GLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPST 1366 Query: 498 AIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQ 557 + + + DA PGPP + E+ V + W+PP L Y I + S Sbjct: 1367 PLILERTKDDA--PGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHT 1424 Query: 558 RVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGR 617 + ++ DL +Y+FR+ + R G EP E T + P Sbjct: 1425 FTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELL 1484 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYY-VDCCVAGTNLWE----PCNHKPIGYNRFVVH 672 V + T S+ +QW + Y+ + W+ +H+ VV Sbjct: 1485 VPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEA---TACVVD 1541 Query: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYG-ITLLNCDGHSMTLGW 731 L Y R+KA N +G S+ S E++ V VP P G ++ S+ + W Sbjct: 1542 RLRPFTSYKLRLKATNDIGDSDFSSETEA--VTTLQDVPGEPPGSVSATPHTTSSVLIQW 1599 Query: 732 KVPKFSGGSPIL-GYYLDKREVHHK------------------------NWHEVNSSPSK 766 + P+ + +L GY + RE+ ++ ++ VNSS S Sbjct: 1600 QPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSS-ST 1658 Query: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826 T+ + L + YE + A N+ G S P E F EA P ++ + Sbjct: 1659 STMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAP---QNVQVTPLTA 1715 Query: 827 TSLVMLW-KAPVYSGSSPVSGYFVDFREEDA-GEWITVNQTTTANRYLKVSDLQQGKTYV 884 + L + W P S + + GY + + E D+ E + +++ +L Y+ Sbjct: 1716 SQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYL 1775 Query: 885 FRVRAVNANGVGKPSDTSEPVLVEARPGTKEISA 918 + A NA G G SD + +A PG A Sbjct: 1776 VSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLA 1809 Score = 66.2 bits (160), Expect = 2e-10 Identities = 99/412 (24%), Positives = 163/412 (39%), Gaps = 32/412 (7%) Query: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGS----GSWQRV-NAQTA 564 +PG P+ + S IS L + P GK + +I + VG+ W + + Sbjct: 1069 LPGAPSNLVISNISPRSATLQFRPGYD-GKTSISRWIVEGQVGAIGDEEEWVTLYEEENE 1127 Query: 565 VRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNT 624 + + +L Y FR+ N G S S + IQ AP V + Sbjct: 1128 PDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPP-DVAPTSVTVRTAS 1186 Query: 625 KTSVVVQW-----DRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNR-FVVHGLTTGE 678 +TS+ ++W + + +GY + + R F + L Sbjct: 1187 ETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWM 1246 Query: 679 QYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSH-PYGITLLNCDGHSMTLGW-KVPKF 736 +Y +++A NAVG S+V++ + +VPS P ++ + L W VP+ Sbjct: 1247 EYELQMQAFNAVGAGP---WSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQ 1303 Query: 737 SGGSPILGYYLDKREVH---HKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 ILGY + R H V + ++ +L GL + LYE ++ A G Sbjct: 1304 DQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLA--GLRKFVLYELQVLAFTRIGN 1361 Query: 794 GEPSDPS--EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF 851 G PS P E K +A PGP L F EVR TS+ ++W+ P + + GY + + Sbjct: 1362 GVPSTPLILERTKDDA-----PGPPVRLVFPEVRLTSVRIVWQPP-EEPNGIILGYQIAY 1415 Query: 852 R-EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902 R + T + R +DL Y+FR+ A G G+P + + Sbjct: 1416 RLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEAT 1467 Score = 57.0 bits (136), Expect = 1e-07 Identities = 80/348 (22%), Positives = 134/348 (38%), Gaps = 15/348 (4%) Query: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM--YFIEKSVVGSGSWQRVNAQTAVRSPRYA 571 P V A +S ++L+W + ++ L+ Y I R + + Sbjct: 1280 PENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSAL 1339 Query: 572 VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQ 631 + L + Y +VL+ R G PS T I + P P R++ TSV + Sbjct: 1340 LAGLRKFVLYELQVLAFTRIGNGVPS--TPLILERTKDDAPGPPVRLVFPEVRLTSVRIV 1397 Query: 632 WDRPKHEEDL-LGYYVDCCVAGTNLWEPCNHKPIG--YNRFVVHGLTTGEQYIFRVKAVN 688 W P+ + LGY + +A ++ +G +F L YIFR+ A Sbjct: 1398 WQPPEEPNGIILGYQIAYRLASSSP-HTFTTVEVGATVRQFTATDLAPESAYIFRLSAKT 1456 Query: 689 AVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLD 748 G E + + + + P + S+ L W VP G SPI + + Sbjct: 1457 RQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW-VPGSDGASPIRYFTMQ 1515 Query: 749 KREVHHKNWHEVNSSPS-KPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEA 807 RE+ W +SS S + T VD L + Y+ ++ A N G SD S + Sbjct: 1516 VRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIG---DSDFSSETEAVT 1572 Query: 808 WTMPEPG-PAYDLTFCEVRDTSLVMLWKAP-VYSGSSPVSGYFVDFRE 853 PG P ++ +S+++ W+ P S + + GY + +RE Sbjct: 1573 TLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRE 1620 Score = 55.8 bits (133), Expect = 3e-07 Identities = 84/345 (24%), Positives = 143/345 (41%), Gaps = 19/345 (5%) Query: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSA-PGRVLASRNTKTSV 628 + + +L E Y ++ + N G SE+ ++ + VPSA P V A + T + Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSEV---VRGRTRESVPSAAPENVSAEAVSSTQI 1293 Query: 629 VVQWDR-PKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNR--FVVHGLTTGEQYIFR 683 ++ W P+ +++ +LGY + + EP +H G + ++ GL Y + Sbjct: 1294 LLTWTSVPEQDQNGLILGYKILFRAKDLDP-EPRSHIVRGNHTQSALLAGLRKFVLYELQ 1352 Query: 684 VKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPIL 743 V A +G S + +I + P P + S+ + W+ P+ G IL Sbjct: 1353 VLAFTRIGNGVPS--TPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI-IL 1409 Query: 744 GYYLDKREVHHKNWHEVNSSPSKPTI--LTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSE 801 GY + R + + H + T+ T L S Y F+++A G GEP + + Sbjct: 1410 GYQIAYR-LASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATV 1468 Query: 802 HFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWIT 861 E P P + EV SL + W P G+SP+ + + RE GEW T Sbjct: 1469 -ITTEKRERPAPPRELLVPQAEVTARSLRLQW-VPGSDGASPIRYFTMQVRELPRGEWQT 1526 Query: 862 VNQTTTANRYLKVSD-LQQGKTYVFRVRAVNANGVGKPSDTSEPV 905 + + + V D L+ +Y R++A N G S +E V Sbjct: 1527 YSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAV 1571 Score = 53.5 bits (127), Expect = 1e-06 Identities = 88/358 (24%), Positives = 134/358 (37%), Gaps = 74/358 (20%) Query: 370 LFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESP-VMGYFVDRCEVGTNN 428 +FV +A P + AP ++Q + VTW PP +++ + GY + E + N Sbjct: 1694 VFVGEAAPAM-----APQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQN 1748 Query: 429 WVQCNDAPVKICKYPVT---GLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 + V PV L Y+ + A N+AG S DP R Sbjct: 1749 --ETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKS---------DPQQGRT 1797 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSW-EPPTPRG------ 538 QA PG P+ + SEI+ + +SW EP G Sbjct: 1798 HQAA---------------------PGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYR 1836 Query: 539 --KDPL--MYFIEKSVVGS--GSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHG 592 +PL + + K V G+WQR V DL +G +Y FRV + Sbjct: 1837 VVYEPLAPVQGVSKVVTVEVRGNWQRW----------LKVRDLTKGVTYFFRVQART--- 1883 Query: 593 LSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDL--LGYYVDCCV 650 ++ E+ + I A P +P VL +++ + + +QW H D GY ++ Sbjct: 1884 ITYGPELQANITAGPAEGSPGSPRDVLVTKSA-SELTLQWTEG-HSGDTPTTGYVIEARP 1941 Query: 651 AGTNLWEP-CNHKPIGYNRFVVH--GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ 705 + LW+ P + + L G Y FRV AVN G E S S + Q Sbjct: 1942 SDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQ 1999 Score = 37.0 bits (84), Expect = 0.14 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 10/104 (9%) Query: 1355 TIMEGKT--LNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 T+ +G+ LNL + P P+V WF+ I S ++ +E + I T+ D Sbjct: 201 TVSQGRAAILNLL-PITSYPRPQVTWFREGHKIIPSNRIAITLEN----QLVILATTTSD 255 Query: 1413 SGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLI 1456 +G Y + N+ GE S + H D+ P+ P ++ Sbjct: 256 AGAYYVQAVNEKNGEN---KTSPFIHLSIARDVGTPETMAPTIV 296 Score = 34.7 bits (78), Expect = 0.69 Identities = 27/122 (22%), Positives = 45/122 (36%), Gaps = 13/122 (10%) Query: 293 ETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGL 352 ETV + C + P P +WY+D + + + + L L +D G+ Sbjct: 402 ETVDIGCQAMGVP-----LPTLQWYKDAISISRLQ-NPRYKVLASGGLRIQKLRPEDSGI 455 Query: 353 YTLRIVSRGGVSDHSAFLFVRDADPLVTGAP-------GAPMDLQCHDANRDYVIVTWKP 405 + + GG +L V + P+ T P G L+C + +TWK Sbjct: 456 FQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKR 515 Query: 406 PN 407 N Sbjct: 516 EN 517 Score = 33.9 bits (76), Expect = 1.2 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 6/89 (6%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYV---SMTIKG 1407 P T+ +G T L C V G P P + W K + I S SV++ + + + I Sbjct: 486 PVDTTVTDGMTAILRCEVSGAPKPAITW-KRENHILASG--SVRIPRFMLLESGGLQIAP 542 Query: 1408 VTSEDSGKYSINIKNKYGGEKIDVTVSVY 1436 V +D+G Y+ N G T++V+ Sbjct: 543 VFIQDAGNYTCYAANTEGSLNASATLTVW 571 >gi|19743806 roundabout 1 isoform b [Homo sapiens] Length = 1612 Score = 99.8 bits (247), Expect = 2e-20 Identities = 151/698 (21%), Positives = 262/698 (37%), Gaps = 121/698 (17%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 266 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V +EP Sbjct: 267 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV------QEP------ 311 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 312 ------------PHFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 350 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 351 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 410 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 411 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 451 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 452 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 495 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 496 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 555 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 556 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 613 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 614 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 671 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 672 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 731 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 732 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 789 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 790 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 827 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 521 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 579 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 580 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 637 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 638 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 697 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 698 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 757 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 758 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 812 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 813 VAASTGAGSGVKSEPQFIQ 831 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 426 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 482 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 483 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 526 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 73 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 131 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 132 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 182 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 183 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 227 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 228 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 273 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 53 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 112 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 113 YLGEAVSHNASLEVAILRDD 132 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 326 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 381 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 382 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 416 >gi|4506569 roundabout 1 isoform a [Homo sapiens] Length = 1651 Score = 99.8 bits (247), Expect = 2e-20 Identities = 151/698 (21%), Positives = 262/698 (37%), Gaps = 121/698 (17%) Query: 142 ERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPG 201 E E + P + R + V S + +G P P V+W KD + ++ Sbjct: 250 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS---- 305 Query: 202 KYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGL 261 +Y I + HTL+I + D +Y+ VA N G+ +A + V +EP Sbjct: 306 RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV------QEP------ 350 Query: 262 PIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDD- 320 HF V+ ++ G TVT +C P QP W R+ Sbjct: 351 ------------PHFVVKPRDQVVAL----GRTVTFQCEATGNP-----QPAIFWRREGS 389 Query: 321 ----VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDAD 376 + + + F L+ +++ + D G Y + ++ G A+L V D Sbjct: 390 QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 449 Query: 377 PLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRC-----EVGTNNW-- 429 A+R ++ P N T V G FV C V T W Sbjct: 450 -----------------ADRPPPVIRQGPVNQTVA--VDGTFVLSCVATGSPVPTILWRK 490 Query: 430 ----VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRR 485 V D+ +K + + + ++R R + ++ + Sbjct: 491 DGVLVSTQDSRIK----------QLENGVLQIRYAKLGDTGRYTCIASTPSG------EA 534 Query: 486 LQAVHLEGEKEIAIYQDDLEGDAQ-VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMY 544 + ++E ++ Q D +P P+ +++SRN V LSW+P G P Y Sbjct: 535 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSY 594 Query: 545 FIEKSVVGSG-SWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603 IE SG SWQ V V++ A+ L Y+F V +AN +G+S+PS+I+ P+ Sbjct: 595 IIEAFSHASGSSWQTVAEN--VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 652 Query: 604 QAQDVTVVPSAPG------------RVLASRN----TKTSVVVQWDRPKHEEDLLGYYVD 647 + QD V+P++ G VL N + +S+ V W + + + GY + Sbjct: 653 KTQD--VLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKIL 710 Query: 648 CCVAGTNL----WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIK 703 +G N W + N V+ L G Y + + +S+ Sbjct: 711 YRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKT 770 Query: 704 VQAALTVPSHPYGITLLNCDGH--SMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVN 761 ++ A + P P G+T+ DG+ ++ + W+ P + ++ Y + +H Sbjct: 771 LEEAPSAP--PQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINK 828 Query: 762 SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799 + + + L G Y ++AA AG G S+P Sbjct: 829 TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 866 Score = 50.1 bits (118), Expect = 2e-05 Identities = 67/319 (21%), Positives = 116/319 (36%), Gaps = 34/319 (10%) Query: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDK-REVHHKNWHEVNSSPSKPT 768 +PS P + + +++TL W+ P + G+ Y ++ +W V + T Sbjct: 560 IPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 618 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTS 828 + GL ++Y F + A N GI +PS S+ K + G + E+ + + Sbjct: 619 S-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-A 676 Query: 829 LVMLWKAPVYSGSSP------------VSGYFVDFREEDAG----EWITVNQTTTANRYL 872 ++ L V S SS + GY + +R A +W+ T A + Sbjct: 677 VLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSV 736 Query: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGV---DEQGNIYL- 928 + DL++G Y + R G S+ +E P V D G L Sbjct: 737 VIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILV 796 Query: 929 -----GFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVS 983 D Q WC + ++ R+ I D S + P YSV Sbjct: 797 SWQPPPEDTQNGMVQEYKVWC-----LGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 851 Query: 984 VSDTDGVSSSFVLDPEELE 1002 V+ + G S +P+ ++ Sbjct: 852 VAASTGAGSGVKSEPQFIQ 870 Score = 37.7 bits (86), Expect = 0.082 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414 T+ T L+C G+P P ++W K+ + + +++Q + + I+ D+G Sbjct: 465 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS---RIKQLENGVLQIRYAKLGDTG 521 Query: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASAS 1461 +Y+ G + V + G +P + PP+ P LIP++ S Sbjct: 522 RYTCIASTPSGEATWSAYIEVQEFG--VP-VQPPRPTDPNLIPSAPS 565 Score = 36.2 bits (82), Expect = 0.24 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 43/275 (15%) Query: 1165 KDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVS---ILEIAGKVYD 1221 KDD LP+ ++ + S+ D G Y ++ G+ VS LE+A + D Sbjct: 112 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA-ILRD 170 Query: 1222 DMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSS-EHMRIG 1280 D S V P + C P E ++W + + E + I Sbjct: 171 DFRQNPSDVMVAVGEPAVMECQPPRGH---------PEPTISWKKDGSPLDDKDERITIR 221 Query: 1281 GSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAE 1340 G + L I + D GKY ++ G+ E AE + +F + Sbjct: 222 GGK----LMITYTRKSDAGKYVCV----------GTNMVGERESEV-AELTVLERPSFVK 266 Query: 1341 KNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY 1400 + P + + + C G+P P V W K+D ++ S + E Sbjct: 267 R---------PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRY-----EIRDD 312 Query: 1401 VSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435 ++ I+ VT+ D G Y+ +N G + T++V Sbjct: 313 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 178 QGFPTPVVQWYKDGSLI-CQAAEPGKYRIESNYG-VHTLEI--NRADFDDTATYSAVATN 233 +G PTP ++WYK G + +P +R+ G + L I R D Y VA N Sbjct: 92 EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN 151 Query: 234 AHGQ-VSTNAAVVVRRFRGD 252 G+ VS NA++ V R D Sbjct: 152 YLGEAVSHNASLEVAILRDD 171 Score = 33.5 bits (75), Expect = 1.5 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 1359 GKTLNLTCTVFGNPDPEVIWFKND--------QDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 G+T+ C GNP P + W + Q Q S FSV ++ +TI V Sbjct: 365 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV----SQTGDLTITNVQR 420 Query: 1411 EDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPP 1448 D G Y N G +T + + + I D PP Sbjct: 421 SDVGYYICQTLNVAGS---IITKAYLEVTDVIADRPPP 455 >gi|104487006 protein tyrosine phosphatase, receptor type, sigma isoform 1 precursor [Homo sapiens] Length = 1948 Score = 97.1 bits (240), Expect = 1e-19 Identities = 180/816 (22%), Positives = 309/816 (37%), Gaps = 143/816 (17%) Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYR----- 204 I P++ V R+ T + LC G P P + W+KD + +A G+ + Sbjct: 137 IDMGPQLKVVERTRT-----ATMLC-AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSE 190 Query: 205 -IESNYGVHTLEINRADFDDTATYSAVATNAHG-QVSTNAAVVVRRFRGDEEPFRSVGLP 262 ES L+I ++ D Y VATN+ G + S+ A + VR R R V Sbjct: 191 TFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELR----EVRRVA-- 244 Query: 263 IGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYR--DD 320 P S++P +H + G V + C + +P P +W + +D Sbjct: 245 ---PRFSILPMSHEIMP------------GGNVNITCVAVGSP-----MPYVKWMQGAED 284 Query: 321 VLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVT 380 + ++ M G L+ D YT +S GV + A + V+ + Sbjct: 285 LTPEDD----MPVGRNVLELT----DVKDSANYTCVAMSSLGVIEAVAQITVKS----LP 332 Query: 381 GAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKIC 440 APG PM + + +TW N PV Y ++ + Q + + Sbjct: 333 KAPGTPM---VTENTATSITITWDSGNP---DPVSYYVIEYKSKSQDGPYQIKE-DITTT 385 Query: 441 KYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIY 500 +Y + GL Y V AVNS G PS V GE+ A Sbjct: 386 RYSIGGLSPNSEYEIWVSAVNSIGQGPPSE----------------SVVTRTGEQAPA-- 427 Query: 501 QDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT-PRG--KDPLMYFIEKSVVGSGSWQ 557 P V A +S +++ WE P P G + +Y+ + G+WQ Sbjct: 428 -----------SAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQ 476 Query: 558 RVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGR 617 + N ++ + V L+E ++Y RVL+ G ++ PIQ + VP P Sbjct: 477 KHNVDDSLLT---TVGSLLEDETYTVRVLAFTSVG---DGPLSDPIQVKTQQGVPGQPMN 530 Query: 618 VLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH-KPIG-----YNRFVV 671 + A ++TS+ + W P+ +E ++ Y + L+ +H + +G +VV Sbjct: 531 LRAEARSETSITLSWSPPR-QESIIKYEL--------LFREGDHGREVGRTFDPTTSYVV 581 Query: 672 HGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS-HPYGITLLNCDGHSMTLG 730 L +Y FR+ A + G+ + V++ + + PS P + ++ ++ + Sbjct: 582 EDLKPNTEYAFRLAARSPQGL---GAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 638 Query: 731 WK-VPKFSGGSPILGYYLDKREVHHKNWH--EVNSSPSKPTILTVDGLTEGSLYEFKIAA 787 W+ P + ++GY + R + ++ EVN P T + ++ L + + Y A Sbjct: 639 WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 698 Query: 788 VNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS-SPVSG 846 G G S P E +P P + + T++ +LW++P + G Sbjct: 699 HTEVGPGPESSPVVVRTDE--DVPS-APPRKVEAEALNATAIRVLWRSPAPGRQHGQIRG 755 Query: 847 YFVDF-REEDA---------------GEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAV 890 Y V + R E A +W T TA + +++LQ Y V A Sbjct: 756 YQVHYVRMEGAEARGPPRIKDVMLADAQWET---DDTAEYEMVITNLQPETAYSITVAAY 812 Query: 891 NANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNI 926 G G S V A G +S +G++ Sbjct: 813 TMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSL 848 Score = 83.2 bits (204), Expect = 2e-15 Identities = 141/605 (23%), Positives = 223/605 (36%), Gaps = 109/605 (18%) Query: 359 SRGGVSDHSAF-LFVRDADPLVTGAPG--------------APMDLQCHDANRDYVIVTW 403 S GG+S +S + ++V + + G P AP ++Q + +IV W Sbjct: 388 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 447 Query: 404 KPPNTTTESPVMGY---FVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + P + GY + E NW + N + V L E +Y RV A Sbjct: 448 EEP-VEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTT--VGSLLEDETYTVRVLAF 504 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 S G S DP+ ++ Q V PG P + A Sbjct: 505 TSVGDGPLS---------DPIQVKTQQGV---------------------PGQPMNLRAE 534 Query: 521 EISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 S + LSW PP R + + Y + + G R +T + Y V DL Sbjct: 535 ARSETSITLSWSPP--RQESIIKYEL---LFREGDHGREVGRTFDPTTSYVVEDLKPNTE 589 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTK-TSVVVQWDRPK--- 636 Y FR+ + + GL T ++ + + PSAP + + + + T+++V W P Sbjct: 590 YAFRLAARSPQGLGA---FTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPET 646 Query: 637 HEEDLLGYYVDCCVAGTNLWEP--CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 H L+GY V G+ EP N P + ++ L QY A VG Sbjct: 647 HNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGP 706 Query: 695 NSQESDVIKVQAALTVPSHP-YGITLLNCDGHSMTLGWKVPKFSGG-SPILGYYLDKREV 752 ES + V+ VPS P + + ++ + W+ P I GY +V Sbjct: 707 ---ESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGY-----QV 758 Query: 753 HHKNWH--EVNSSPSKPTILTVDG----------------LTEGSLYEFKIAAVNLAGIG 794 H+ E P ++ D L + Y +AA + G G Sbjct: 759 HYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDG 818 Query: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854 S P A + P L+ + + SL+ W+ P + V GY + F E Sbjct: 819 ARSKPKVVVTKGA-VLGRP----TLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGRE 873 Query: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK--------PSDT--SEP 904 D+ T+ + +RY S + +G TYVFR+ A + G+G+ P DT P Sbjct: 874 DSTPLATLEFPPSEDRY-TASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHP 932 Query: 905 VLVEA 909 ++EA Sbjct: 933 QILEA 937 Score = 44.7 bits (104), Expect = 7e-04 Identities = 51/245 (20%), Positives = 90/245 (36%), Gaps = 43/245 (17%) Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN--DAPVKICKYPVTGLFEGRSYIFR 456 ++ W+PP T E V+GY R + G + + P +Y +G+ +G +Y+FR Sbjct: 848 LLARWEPPAGTAEDQVLGY---RLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFR 904 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 + A + G+ E + ++I +D G Q+ Sbjct: 905 LAARSRGGLGE------------------------EAAEVLSIPEDTPRGHPQILEA--- 937 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM--YFIEKSVVGSGSWQRVNAQTAVRSP----RY 570 A S V+L W PP P ++ + Y + G+ R A P Sbjct: 938 --AGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENAL 995 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 + L +Y +V + R G P + P++ + +P KTSV++ Sbjct: 996 TLQGLKPDTAYDLQVRAHTRRG---PGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLL 1052 Query: 631 QWDRP 635 W+ P Sbjct: 1053 SWEFP 1057 Score = 38.1 bits (87), Expect = 0.063 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKN--DQDIQLSEHFSVKVEQAKYVSMTIKGV 1408 P + + +T + C GNPDPE+ WFK+ D S ++ + S I+G Sbjct: 141 PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGA 200 Query: 1409 ----TSE--DSGKYSINIKNKYG 1425 +SE D GKY N G Sbjct: 201 LQIESSEETDQGKYECVATNSAG 223 Score = 32.7 bits (73), Expect = 2.6 Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDI 1385 LP IM G +N+TC G+P P V W + +D+ Sbjct: 250 LPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDL 285 Score = 31.2 bits (69), Expect = 7.7 Identities = 19/100 (19%), Positives = 42/100 (42%), Gaps = 2/100 (2%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV-TSEDSGK 1415 + G + C G+P P V W K + + +++ +++ + I+ + T D Sbjct: 45 VSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104 Query: 1416 YSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKL 1455 Y +N G + ++V + +++P P P+L Sbjct: 105 YECVAQNSVGEITVHAKLTVLRE-DQLPSGFPNIDMGPQL 143 >gi|157311649 neogenin homolog 1 [Homo sapiens] Length = 1461 Score = 96.7 bits (239), Expect = 1e-19 Identities = 143/655 (21%), Positives = 246/655 (37%), Gaps = 129/655 (19%) Query: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230 V L G PTP ++W K+ + + + +LEI+ DD TY + Sbjct: 266 VVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG----SLEISDVTEDDAGTYFCI 321 Query: 231 ATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR 290 A N + + A + V+ +FL++ + Sbjct: 322 ADNGNETIEAQAELTVQA----------------------------QPEFLKQPTNIYAH 353 Query: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350 E + +C + P P +W ++ ++ S + K+ + +L L K DE Sbjct: 354 ESMDIVFECEVTGKP-----TPTVKWVKNGDMVIPSDYFKIV---KEHNLQVLGLVKSDE 405 Query: 351 GLYTLRIVSRGGVSDHSAFLFVRDADPLVTG-APGAPMDLQCHDANRDYVIVTWKPPNTT 409 G Y + G + A L + + P TG P AP D+ + ++ +TW+ P + Sbjct: 406 GFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASD 465 Query: 410 TESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPS 469 + Y V + G N + + + L YIFRV A N G S Sbjct: 466 PHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESS 525 Query: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529 A + + + + Q+PGP + A S + + Sbjct: 526 ----------------------------APLRVETQPEVQLPGPAPNLRAYAASPTSITV 557 Query: 530 SWEPPTPRG---KDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVL 586 +WE P ++ +Y++EK G+ Q V+ V S Y + L + Y FRV+ Sbjct: 558 TWETPVSGNGEIQNYKLYYMEK---GTDKEQDVD----VSSHSYTINGLKKYTEYSFRVV 610 Query: 587 SANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA--SRNTKTSVVVQWDRP---KHEEDL 641 + N+HG P T + + ++ VPSA + L+ RN+K S+++ W P + Sbjct: 611 AYNKHG---PGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSK-SIMIHWQPPAPATQNGQI 666 Query: 642 LGYYV------------DCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA--V 687 GY + + V+GT L + ++ GL G +Y FRV A + Sbjct: 667 TGYKIRYRKASRKSDVTETLVSGTQLSQ------------LIEGLDRGTEYNFRVAALTI 714 Query: 688 NAVG-----MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPI 742 N G +S + ESD+ + + VPS + L+ S+ + W P+ + + Sbjct: 715 NGTGPATDWLSAETFESDLDETRVP-EVPSSLHVRPLVT----SIVVSWTPPE-NQNIVV 768 Query: 743 LGYYLDKR-EVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEP 796 GY + H +V+ K T++ L S Y + A N G G P Sbjct: 769 RGYAIGYGIGSPHAQTIKVD---YKQRYYTIENLDPSSHYVITLKAFNNVGEGIP 820 Score = 94.0 bits (232), Expect = 1e-18 Identities = 147/648 (22%), Positives = 253/648 (39%), Gaps = 101/648 (15%) Query: 277 DVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEG 336 D+ FL++ R G+ V L C P P +W +++ L ++ G Sbjct: 248 DLVFLKQPSPLVRVIGQDVVLPCVASGLPT-----PTIKWMKNEEALDTESSERLVLLAG 302 Query: 337 QASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPG---APMDLQCHD 393 SL S + +DD G Y ++D+ A+ V P P ++ H+ Sbjct: 303 -GSLEISDVTEDDAGTYFC-------IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHE 354 Query: 394 ANRDYVI---VTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPV-----KICK---Y 442 + D V VT KP T WV+ D + KI K Sbjct: 355 S-MDIVFECEVTGKPTPTV------------------KWVKNGDMVIPSDYFKIVKEHNL 395 Query: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 V GL + ++ A N G + + ++ I + Sbjct: 396 QVLGLVKSDEGFYQCIAENDVG-------------------------NAQAGAQLIILEH 430 Query: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT--PRGKDPLMYFIEKSVVGSGSWQRVN 560 +P P V AS +S ++ L+W P P G D L Y + + G +RV Sbjct: 431 APATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHG-DNLTYSVFYTKEGIAR-ERVE 488 Query: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLA 620 + + + +LM Y+FRV++ N+HG E S ++ Q +P + A Sbjct: 489 NTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE-SSAPLRVETQPEVQLPGPAPNLRA 547 Query: 621 SRNTKTSVVVQWDRP-KHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQ 679 + TS+ V W+ P ++ Y + GT+ + + + + + ++GL + Sbjct: 548 YAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVD---VSSHSYTINGLKKYTE 604 Query: 680 YIFRVKAVNAVGMSENSQESDVIKVQAALTVPS-HPYGITLLNCDGHSMTLGWKVP-KFS 737 Y FRV A N G ++ + + V+ VPS P ++L + S+ + W+ P + Sbjct: 605 YSFRVVAYNKHGPGVSTPD---VAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPAT 661 Query: 738 GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILT--VDGLTEGSLYEFKIAAVNLAGIGE 795 I GY + R+ K+ +V + T L+ ++GL G+ Y F++AA+ + G G Sbjct: 662 QNGQITGYKIRYRKASRKS--DVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGP 719 Query: 796 PSD--PSEHFKCEAWTMPEPGPAYDLTFCEVRD--TSLVMLWKAPVYSGSSPVSGYFVDF 851 +D +E F+ + P L VR TS+V+ W P + + V GY + + Sbjct: 720 ATDWLSAETFESDLDETRVPEVPSSL---HVRPLVTSIVVSW-TPPENQNIVVRGYAIGY 775 Query: 852 R-EEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKP 898 + I V+ RY + +L YV ++A N G G P Sbjct: 776 GIGSPHAQTIKVDY---KQRYYTIENLDPSSHYVITLKAFNNVGEGIP 820 Score = 71.2 bits (173), Expect = 7e-12 Identities = 77/295 (26%), Positives = 122/295 (41%), Gaps = 15/295 (5%) Query: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEE--DLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668 +PSAP V+AS + + + W P + D L Y V G N G + Sbjct: 438 LPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQ 497 Query: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMT 728 + L YIFRV A N G E+S V + Q + +P + S+T Sbjct: 498 VTIQNLMPATVYIFRVMAQNKHGSGESSAPLRV-ETQPEVQLPGPAPNLRAYAASPTSIT 556 Query: 729 LGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAV 788 + W+ P SG I Y L E +V+ S T++GL + + Y F++ A Sbjct: 557 VTWETP-VSGNGEIQNYKLYYMEKGTDKEQDVDVSSHS---YTINGLKKYTEYSFRVVAY 612 Query: 789 NLAGIGEPSDPSEHFKCEAWTMPE-PGPAYDLTFCEVRDTSLVML-WKAPV-YSGSSPVS 845 N G G S P + T+ + P A EVR++ +M+ W+ P + + ++ Sbjct: 613 NKHGPGV-STPDVAVR----TLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQIT 667 Query: 846 GYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900 GY + +R+ +T + + L +G Y FRV A+ NG G +D Sbjct: 668 GYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATD 722 Score = 70.9 bits (172), Expect = 9e-12 Identities = 160/807 (19%), Positives = 301/807 (37%), Gaps = 148/807 (18%) Query: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206 E + PE L + + E M + V G PTP V+W K+G ++ + ++I Sbjct: 334 ELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS---DYFKIV 390 Query: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLP 266 + + L + ++D Y +A N G A +++ + P + LP Sbjct: 391 KEHNLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIIL----EHAPATTGPLPSAPR 443 Query: 267 --LSSMIPYTHFDVQFLEKFGVTFRR-----EGETVTLKCTMLVTPDLKRVQPRAEWYRD 319 ++S++ +F++ +T+R G+ +T +Y Sbjct: 444 DVVASLV-----STRFIK---LTWRTPASDPHGDNLTYSV----------------FYTK 479 Query: 320 DVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLV 379 + + +E GE Q ++ +L ++ + ++ G + SA L V + P V Sbjct: 480 EGIARERVENTSHPGEMQVTIQ--NLMPATVYIFRVMAQNKHGSGESSAPLRV-ETQPEV 536 Query: 380 TGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKI 439 PG +L+ + A+ + VTW+ P + + Y + E GT+ D V Sbjct: 537 Q-LPGPAPNLRAYAASPTSITVTWETP-VSGNGEIQNYKLYYMEKGTDKE---QDVDVSS 591 Query: 440 CKYPVTGLFEGRSYIFRVRAVNS--AGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEI 497 Y + GL + Y FRV A N G+S P AV L + Q + LE Sbjct: 592 HSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDV---AVRTLSDVPSAAPQNLSLEVRNSK 648 Query: 498 AIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQ 557 +I ++ W+PP P ++ + K S + Sbjct: 649 SI----------------------------MIHWQPPAPATQNGQITGY-KIRYRKASRK 679 Query: 558 RVNAQTAVRSPRYA--VFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ---DVTVVP 612 +T V + + + L G Y FRV + +G ++ S + D T VP Sbjct: 680 SDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP 739 Query: 613 SAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEP-CNHKPIGYNR--F 669 P L R TS+VV W P+++ ++ Y G + P + Y + + Sbjct: 740 EVPSS-LHVRPLVTSIVVSWTPPENQNIVVRGYA----IGYGIGSPHAQTIKVDYKQRYY 794 Query: 670 VVHGLTTGEQYIFRVKAVNAVGMS------------ENSQESDVIKVQAALT-VPSH--- 713 + L Y+ +KA N VG ++ E D+ + A T VP Sbjct: 795 TIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPM 854 Query: 714 --PYGITLLNCDGHSMTLGW---KVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPT 768 P G+ ++ + W +PK + Y + + N N++ + + Sbjct: 855 MPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLS 914 Query: 769 ILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFC------ 822 L V GL +LYEF + ++ + W+M G ++L Sbjct: 915 YL-VTGLKPNTLYEFSVMV------------TKGRRSSTWSMTAHGTTFELVPTSPPKDV 961 Query: 823 -----EVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE---DAGEWITVNQTTTANRYL-K 873 E + ++++ W+ P + ++GY + + + + +W+ + NR + Sbjct: 962 TVVSKEGKPKTIIVNWQPPS-EANGKITGYIIYYSTDVNAEIHDWVI--EPVVGNRLTHQ 1018 Query: 874 VSDLQQGKTYVFRVRAVNANGVGKPSD 900 + +L Y F+++A N+ G+G S+ Sbjct: 1019 IQELTLDTPYYFKIQARNSKGMGPMSE 1045 Score = 50.1 bits (118), Expect = 2e-05 Identities = 63/279 (22%), Positives = 106/279 (37%), Gaps = 40/279 (14%) Query: 1185 LLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTP 1244 L+I ++ D G Y+ ++ S E+ KV D + V K SPL V Sbjct: 206 LVISNATEGDGGLYRCVVESGGPPKYSD-EVELKVLPDPEVISDLVFLKQPSPL-VRVIG 263 Query: 1245 EGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI----GGSEEMAWLQICEPTEKDKGK 1300 + + L C + W + + + R+ GGS L+I + TE D G Sbjct: 264 QDVVLPCVASGLPTPT-IKWMKNEEALDTESSERLVLLAGGS-----LEISDVTEDDAGT 317 Query: 1301 YTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGK 1360 Y F DN +++ + +A EF + +A ++ D+V Sbjct: 318 Y----FCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESM--------DIV------ 359 Query: 1361 TLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINI 1420 C V G P P V W KN + S++F + E ++ + G+ D G Y Sbjct: 360 ---FECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEH----NLQVLGLVKSDEGFYQCIA 412 Query: 1421 KNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPAS 1459 +N G + + + +H P P + P+ + AS Sbjct: 413 ENDVGNAQAGAQLIILEHA---PATTGPLPSAPRDVVAS 448 Score = 38.1 bits (87), Expect = 0.063 Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 3/105 (2%) Query: 807 AWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTT 866 A T P P D+ V + + W+ P Y V + +E N + Sbjct: 433 ATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSH 492 Query: 867 TANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARP 911 + + +L Y+FRV A N +G G ++S P+ VE +P Sbjct: 493 PGEMQVTIQNLMPATVYIFRVMAQNKHGSG---ESSAPLRVETQP 534 >gi|104487297 protein tyrosine phosphatase, receptor type, sigma isoform 2 precursor [Homo sapiens] Length = 1910 Score = 92.4 bits (228), Expect = 3e-18 Identities = 172/798 (21%), Positives = 304/798 (38%), Gaps = 129/798 (16%) Query: 150 ISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209 I P++ V R+ T + LC G P P + W+KD + +A G+ + Sbjct: 137 IDMGPQLKVVERTRT-----ATMLC-AASGNPDPEITWFKDFLPVDPSASNGRIK---QL 187 Query: 210 GVHTLEINRADFDDTATYSAVATNAHG-QVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLS 268 L+I ++ D Y VATN+ G + S+ A + VR R V P Sbjct: 188 RSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR--------VRRVA-----PRF 234 Query: 269 SMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYR--DDVLLKES 326 S++P +H + G V + C + +P P +W + +D+ ++ Sbjct: 235 SILPMSHEIMP------------GGNVNITCVAVGSP-----MPYVKWMQGAEDLTPEDD 277 Query: 327 KWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAP 386 M G L+ D YT +S GV + A + V+ + APG P Sbjct: 278 ----MPVGRNVLELT----DVKDSANYTCVAMSSLGVIEAVAQITVKS----LPKAPGTP 325 Query: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446 M + + +TW N PV Y ++ + Q + + +Y + G Sbjct: 326 M---VTENTATSITITWDSGNP---DPVSYYVIEYKSKSQDGPYQIKE-DITTTRYSIGG 378 Query: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506 L Y V AVNS G PS V GE+ A Sbjct: 379 LSPNSEYEIWVSAVNSIGQGPPSE----------------SVVTRTGEQAPA-------- 414 Query: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPT-PRG--KDPLMYFIEKSVVGSGSWQRVNAQT 563 P V A +S +++ WE P P G + +Y+ + G+WQ+ N Sbjct: 415 -----SAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDD 469 Query: 564 AVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRN 623 ++ + V L+E ++Y RVL+ G ++ PIQ + VP P + A Sbjct: 470 SLLT---TVGSLLEDETYTVRVLAFTSVG---DGPLSDPIQVKTQQGVPGQPMNLRAEAR 523 Query: 624 TKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNH-KPIG-----YNRFVVHGLTTG 677 ++TS+ + W P+ +E ++ Y + L+ +H + +G +VV L Sbjct: 524 SETSITLSWSPPR-QESIIKYEL--------LFREGDHGREVGRTFDPTTSYVVEDLKPN 574 Query: 678 EQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPS-HPYGITLLNCDGHSMTLGWK-VPK 735 +Y FR+ A + G+ + V++ + + PS P + ++ ++ + W+ P Sbjct: 575 TEYAFRLAARSPQGL---GAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPP 631 Query: 736 FSGGSPILGYYLDKREVHHKNWH--EVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793 + ++GY + R + ++ EVN P T + ++ L + + Y A G Sbjct: 632 ETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGP 691 Query: 794 GEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS-SPVSGYFVDFR 852 G S P E +P P + + T++ +LW++P + GY V + Sbjct: 692 GPESSPVVVRTDE--DVPS-APPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYV 748 Query: 853 EEDAGEW---ITVNQTTTAN-RYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE 908 + E + A+ + + +++LQ Y V A G G S V Sbjct: 749 RMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKG 808 Query: 909 ARPGTKEISAGVDEQGNI 926 A G +S +G++ Sbjct: 809 AVLGRPTLSVQQTPEGSL 826 Score = 86.7 bits (213), Expect = 2e-16 Identities = 141/596 (23%), Positives = 223/596 (37%), Gaps = 100/596 (16%) Query: 359 SRGGVSDHSAF-LFVRDADPLVTGAPG--------------APMDLQCHDANRDYVIVTW 403 S GG+S +S + ++V + + G P AP ++Q + +IV W Sbjct: 375 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 434 Query: 404 KPPNTTTESPVMGY---FVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAV 460 + P + GY + E NW + N + V L E +Y RV A Sbjct: 435 EEP-VEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTT--VGSLLEDETYTVRVLAF 491 Query: 461 NSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHAS 520 S G S DP+ ++ Q V PG P + A Sbjct: 492 TSVGDGPLS---------DPIQVKTQQGV---------------------PGQPMNLRAE 521 Query: 521 EISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580 S + LSW PP R + + Y + + G R +T + Y V DL Sbjct: 522 ARSETSITLSWSPP--RQESIIKYEL---LFREGDHGREVGRTFDPTTSYVVEDLKPNTE 576 Query: 581 YVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTK-TSVVVQWDRPK--- 636 Y FR+ + + GL T ++ + + PSAP + + + + T+++V W P Sbjct: 577 YAFRLAARSPQGLGA---FTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPET 633 Query: 637 HEEDLLGYYVDCCVAGTNLWEP--CNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSE 694 H L+GY V G+ EP N P + ++ L QY A VG Sbjct: 634 HNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGP 693 Query: 695 NSQESDVIKVQAALTVPSHP-YGITLLNCDGHSMTLGWKVPKFSGG-SPILGYYLDKREV 752 ES + V+ VPS P + + ++ + W+ P I GY +V Sbjct: 694 ---ESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGY-----QV 745 Query: 753 HHKNWH--EVNSSPSKPTILTVDG-------LTEGSLYEFKIAAVNLAGIGEPSDPSEHF 803 H+ E P ++ D L + Y +AA + G G S P Sbjct: 746 HYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVV 805 Query: 804 KCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVN 863 A + P L+ + + SL+ W+ P + V GY + F ED+ T+ Sbjct: 806 TKGA-VLGRP----TLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLE 860 Query: 864 QTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGK--------PSDT--SEPVLVEA 909 + +RY S + +G TYVFR+ A + G+G+ P DT P ++EA Sbjct: 861 FPPSEDRY-TASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEA 915 Score = 44.7 bits (104), Expect = 7e-04 Identities = 51/245 (20%), Positives = 90/245 (36%), Gaps = 43/245 (17%) Query: 399 VIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN--DAPVKICKYPVTGLFEGRSYIFR 456 ++ W+PP T E V+GY R + G + + P +Y +G+ +G +Y+FR Sbjct: 826 LLARWEPPAGTAEDQVLGY---RLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFR 882 Query: 457 VRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTG 516 + A + G+ E + ++I +D G Q+ Sbjct: 883 LAARSRGGLGE------------------------EAAEVLSIPEDTPRGHPQILEA--- 915 Query: 517 VHASEISRNYVVLSWEPPTPRGKDPLM--YFIEKSVVGSGSWQRVNAQTAVRSP----RY 570 A S V+L W PP P ++ + Y + G+ R A P Sbjct: 916 --AGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENAL 973 Query: 571 AVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVV 630 + L +Y +V + R G P + P++ + +P KTSV++ Sbjct: 974 TLQGLKPDTAYDLQVRAHTRRG---PGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLL 1030 Query: 631 QWDRP 635 W+ P Sbjct: 1031 SWEFP 1035 Score = 43.5 bits (101), Expect = 0.001 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Query: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 P + + +T + C GNPDPE+ WFK+ + S + +++Q + ++ I+ Sbjct: 141 PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEE 199 Query: 1411 EDSGKYSINIKNKYG 1425 D GKY N G Sbjct: 200 TDQGKYECVATNSAG 214 Score = 32.7 bits (73), Expect = 2.6 Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 1350 LPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDI 1385 LP IM G +N+TC G+P P V W + +D+ Sbjct: 237 LPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDL 272 Score = 31.2 bits (69), Expect = 7.7 Identities = 19/100 (19%), Positives = 42/100 (42%), Gaps = 2/100 (2%) Query: 1357 MEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGV-TSEDSGK 1415 + G + C G+P P V W K + + +++ +++ + I+ + T D Sbjct: 45 VSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104 Query: 1416 YSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKL 1455 Y +N G + ++V + +++P P P+L Sbjct: 105 YECVAQNSVGEITVHAKLTVLRE-DQLPSGFPNIDMGPQL 143 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 58,033,254 Number of Sequences: 37866 Number of extensions: 2726768 Number of successful extensions: 17451 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 182 Number of HSP's successfully gapped in prelim test: 214 Number of HSP's that attempted gapping in prelim test: 7062 Number of HSP's gapped (non-prelim): 5350 length of query: 1465 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1350 effective length of database: 13,892,928 effective search space: 18755452800 effective search space used: 18755452800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.