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Search of human proteins with 153945836
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
(765 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 1555 0.0
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 1533 0.0
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 1482 0.0
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 1475 0.0
gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 1006 0.0
gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 1006 0.0
gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 1006 0.0
gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 987 0.0
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 548 e-156
gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 531 e-151
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 459 e-129
gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 359 5e-99
gi|40255251 hypothetical protein LOC131408 [Homo sapiens] 33 0.99
gi|124487387 ring finger protein 207 [Homo sapiens] 33 1.3
gi|239753431 PREDICTED: similar to endothelin converting enzyme-... 32 2.2
gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo ... 32 2.2
gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo ... 32 2.2
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 31 3.8
gi|83641876 serine carboxypeptidase vitellogenic-like [Homo sapi... 30 8.4
gi|83641874 serine carboxypeptidase vitellogenic-like [Homo sapi... 30 8.4
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 30 8.4
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 1555 bits (4026), Expect = 0.0
Identities = 765/765 (100%), Positives = 765/765 (100%)
Query: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLE 60
MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLE
Sbjct: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLE 60
Query: 61 LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF 120
LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF
Sbjct: 61 LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF 120
Query: 121 YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS 180
YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS
Sbjct: 121 YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS 180
Query: 181 CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD 240
CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD
Sbjct: 181 CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD 240
Query: 241 SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ 300
SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ
Sbjct: 241 SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ 300
Query: 301 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 360
QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE
Sbjct: 301 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 360
Query: 361 PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK 420
PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK
Sbjct: 361 PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK 420
Query: 421 KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM 480
KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM
Sbjct: 421 KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM 480
Query: 481 DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM 540
DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM
Sbjct: 481 DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM 540
Query: 541 ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM 600
ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM
Sbjct: 541 ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM 600
Query: 601 GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL 660
GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL
Sbjct: 601 GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL 660
Query: 661 GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE 720
GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE
Sbjct: 661 GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE 720
Query: 721 GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 721 GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 1533 bits (3969), Expect = 0.0
Identities = 765/811 (94%), Positives = 765/811 (94%), Gaps = 46/811 (5%)
Query: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVG---------------- 44
MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVG
Sbjct: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTP 60
Query: 45 ------------------------------FQKGTRQLLGSRTQLELVLAGASLLLAALL 74
FQKGTRQLLGSRTQLELVLAGASLLLAALL
Sbjct: 61 GTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALL 120
Query: 75 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 134
LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL
Sbjct: 121 LGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPL 180
Query: 135 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 194
PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP
Sbjct: 181 PDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQP 240
Query: 195 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 254
LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS
Sbjct: 241 LRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS 300
Query: 255 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 314
GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV
Sbjct: 301 GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITV 360
Query: 315 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 374
PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS
Sbjct: 361 PQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVS 420
Query: 375 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 434
ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT
Sbjct: 421 ELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNT 480
Query: 435 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 494
DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA
Sbjct: 481 DDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADA 540
Query: 495 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 554
IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS
Sbjct: 541 IYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWS 600
Query: 555 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 614
MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE
Sbjct: 601 MTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGRE 660
Query: 615 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 674
YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY
Sbjct: 661 YDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAY 720
Query: 675 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 734
NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV
Sbjct: 721 NAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRV 780
Query: 735 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 781 LGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 1482 bits (3836), Expect = 0.0
Identities = 736/765 (96%), Positives = 736/765 (96%), Gaps = 29/765 (3%)
Query: 1 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLE 60
MNVALQELGAGSN VGFQKGTRQLLGSRTQLE
Sbjct: 1 MNVALQELGAGSN-----------------------------VGFQKGTRQLLGSRTQLE 31
Query: 61 LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF 120
LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF
Sbjct: 32 LVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDF 91
Query: 121 YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS 180
YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS
Sbjct: 92 YQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLS 151
Query: 181 CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD 240
CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD
Sbjct: 152 CLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISAD 211
Query: 241 SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ 300
SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ
Sbjct: 212 SKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQ 271
Query: 301 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 360
QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE
Sbjct: 272 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 331
Query: 361 PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK 420
PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK
Sbjct: 332 PVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTK 391
Query: 421 KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM 480
KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM
Sbjct: 392 KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWM 451
Query: 481 DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM 540
DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM
Sbjct: 452 DEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVM 511
Query: 541 ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM 600
ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM
Sbjct: 512 ADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVM 571
Query: 601 GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL 660
GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL
Sbjct: 572 GHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL 631
Query: 661 GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE 720
GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE
Sbjct: 632 GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHE 691
Query: 721 GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 692 GLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 736
>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
Length = 883
Score = 1475 bits (3818), Expect = 0.0
Identities = 724/724 (100%), Positives = 724/724 (100%)
Query: 42 EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR 101
EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR
Sbjct: 160 EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR 219
Query: 102 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN 161
VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN
Sbjct: 220 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN 279
Query: 162 TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK 221
TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK
Sbjct: 280 TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK 339
Query: 222 AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM 281
AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM
Sbjct: 340 AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM 399
Query: 282 EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM 341
EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM
Sbjct: 400 EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM 459
Query: 342 DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL 401
DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL
Sbjct: 460 DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL 519
Query: 402 DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG 461
DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG
Sbjct: 520 DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG 579
Query: 462 MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS 521
MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS
Sbjct: 580 MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS 639
Query: 522 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP 581
EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP
Sbjct: 640 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP 699
Query: 582 FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME 641
FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME
Sbjct: 700 FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME 759
Query: 642 EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF 701
EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF
Sbjct: 760 EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF 819
Query: 702 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL 761
FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL
Sbjct: 820 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL 879
Query: 762 CEVW 765
CEVW
Sbjct: 880 CEVW 883
>gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo
sapiens]
Length = 767
Score = 1006 bits (2602), Expect = 0.0
Identities = 477/755 (63%), Positives = 601/755 (79%), Gaps = 5/755 (0%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGFQ--KGTRQLLGSRTQLELVLAGASLLLA 71
M YKRATL +ED ++ EG A P+ ++V F + ++ +RTQ+E L +LLA
Sbjct: 15 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLA 74
Query: 72 ALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRR 131
A L+ CL ALG+QY + S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+
Sbjct: 75 AGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKA 133
Query: 132 NPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELG 191
NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL
Sbjct: 134 NPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELR 192
Query: 192 AQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQV 251
A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQV
Sbjct: 193 AKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQV 252
Query: 252 DQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLA 310
DQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LA
Sbjct: 253 DQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALA 312
Query: 311 NITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYL 370
NIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL
Sbjct: 313 NITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYL 372
Query: 371 QQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTC 430
+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C
Sbjct: 373 EQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFC 432
Query: 431 ISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKE 490
+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKE
Sbjct: 433 VSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKE 492
Query: 491 KADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSR 550
KADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +NFS +V ADQLRK P+R
Sbjct: 493 KADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNR 552
Query: 551 DQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDD 610
DQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDD
Sbjct: 553 DQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDD 612
Query: 611 QGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGL 670
QGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGL
Sbjct: 613 QGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGL 672
Query: 671 KAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPA 730
KAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+
Sbjct: 673 KAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPS 732
Query: 731 RFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 733 RFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767
>gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo
sapiens]
Length = 754
Score = 1006 bits (2602), Expect = 0.0
Identities = 477/755 (63%), Positives = 601/755 (79%), Gaps = 5/755 (0%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGFQ--KGTRQLLGSRTQLELVLAGASLLLA 71
M YKRATL +ED ++ EG A P+ ++V F + ++ +RTQ+E L +LLA
Sbjct: 2 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLA 61
Query: 72 ALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRR 131
A L+ CL ALG+QY + S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+
Sbjct: 62 AGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKA 120
Query: 132 NPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELG 191
NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL
Sbjct: 121 NPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELR 179
Query: 192 AQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQV 251
A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQV
Sbjct: 180 AKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQV 239
Query: 252 DQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLA 310
DQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LA
Sbjct: 240 DQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALA 299
Query: 311 NITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYL 370
NIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL
Sbjct: 300 NITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYL 359
Query: 371 QQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTC 430
+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C
Sbjct: 360 EQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFC 419
Query: 431 ISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKE 490
+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKE
Sbjct: 420 VSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKE 479
Query: 491 KADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSR 550
KADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +NFS +V ADQLRK P+R
Sbjct: 480 KADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNR 539
Query: 551 DQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDD 610
DQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDD
Sbjct: 540 DQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDD 599
Query: 611 QGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGL 670
QGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGL
Sbjct: 600 QGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGL 659
Query: 671 KAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPA 730
KAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+
Sbjct: 660 KAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPS 719
Query: 731 RFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 720 RFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754
>gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens]
Length = 770
Score = 1006 bits (2602), Expect = 0.0
Identities = 477/755 (63%), Positives = 601/755 (79%), Gaps = 5/755 (0%)
Query: 14 MVEYKRATLRDEDAPETPVEGGASPDAMEVGFQ--KGTRQLLGSRTQLELVLAGASLLLA 71
M YKRATL +ED ++ EG A P+ ++V F + ++ +RTQ+E L +LLA
Sbjct: 18 MSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLA 77
Query: 72 ALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRR 131
A L+ CL ALG+QY + S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+
Sbjct: 78 AGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKA 136
Query: 132 NPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELG 191
NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL
Sbjct: 137 NPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELR 195
Query: 192 AQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQV 251
A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQV
Sbjct: 196 AKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQV 255
Query: 252 DQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLA 310
DQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LA
Sbjct: 256 DQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALA 315
Query: 311 NITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYL 370
NIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL
Sbjct: 316 NITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYL 375
Query: 371 QQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTC 430
+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C
Sbjct: 376 EQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFC 435
Query: 431 ISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKE 490
+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKE
Sbjct: 436 VSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKE 495
Query: 491 KADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSR 550
KADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +NFS +V ADQLRK P+R
Sbjct: 496 KADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNR 555
Query: 551 DQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDD 610
DQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDD
Sbjct: 556 DQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDD 615
Query: 611 QGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGL 670
QGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGL
Sbjct: 616 QGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGL 675
Query: 671 KAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPA 730
KAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+
Sbjct: 676 KAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPS 735
Query: 731 RFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 736 RFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770
>gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo
sapiens]
Length = 758
Score = 987 bits (2551), Expect = 0.0
Identities = 465/731 (63%), Positives = 586/731 (80%), Gaps = 5/731 (0%)
Query: 38 PDAMEVGFQ--KGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCL 95
P +++V F + ++ +RTQ+E L +LLAA L+ CL ALG+QY + S S CL
Sbjct: 30 PPSLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQY-QTRSPSVCL 88
Query: 96 TEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAIL 155
+EAC+ V IL S+D V PC DF+ ++CGGWI+ NP+PDG SRW TF++LW+ NQAI+
Sbjct: 89 SEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAII 148
Query: 156 KHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDN 215
KHLLEN+T S SEAE+K Q +Y +C+ RIEEL A+PL +LIE++GGWNITGPW +DN
Sbjct: 149 KHLLENSTA-SVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDN 207
Query: 216 FMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLT 275
F + L+ V YR +PFF+VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+T NEKVLT
Sbjct: 208 FQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLT 267
Query: 276 AYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISEL 334
YL+YM +LG LLGG R QMQQ+L+ E LANIT+PQ++RRDEE IYHK++ +EL
Sbjct: 268 GYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAEL 327
Query: 335 QALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLV 394
Q LAP+++WL FL+ + P+E+++SEP+VVY +YL+Q+S LIN T+ +LNNY+IWNLV
Sbjct: 328 QTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLV 387
Query: 395 QKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQ 454
+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C+S+T++ LGFALG +FVKATF
Sbjct: 388 RKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAED 447
Query: 455 SKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDV 514
SK IA +I EI+ AFEE+L L WMDE+TR++AKEKADAIY+MIG+P+FI++PKELD V
Sbjct: 448 SKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKV 507
Query: 515 YDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFP 574
++ Y D +F+N + +NFS +V ADQLRK P+RDQWSMTP VNAYY PTKNEIVFP
Sbjct: 508 FNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFP 567
Query: 575 AGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFR 634
AGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+N S+ AF+
Sbjct: 568 AGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFK 627
Query: 635 NHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVG 694
T CM EQY+ Y VNGE +NGR TLGENIADNGGLKAAY AY+ W++K+G E LP +G
Sbjct: 628 RQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLG 687
Query: 695 LTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGS 754
LTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+RFRV+G+LSNS++F HF CP GS
Sbjct: 688 LTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGS 747
Query: 755 PMNPGQLCEVW 765
PMNP CEVW
Sbjct: 748 PMNPPHKCEVW 758
>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
Length = 779
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 63 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 90
L G LLL L+ LVALGV Y R P
Sbjct: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
Query: 91 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 149
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
Query: 150 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 208
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
Query: 209 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 263
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
Query: 264 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 317
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Query: 318 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 373
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
Query: 374 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 433
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
Query: 434 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 493
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
Query: 494 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 551
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
Query: 552 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 611
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
Query: 612 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 668
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
Query: 669 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 728
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
Query: 729 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
Length = 775
Score = 531 bits (1369), Expect = e-151
Identities = 286/758 (37%), Positives = 435/758 (57%), Gaps = 34/758 (4%)
Query: 34 GGASPDAMEVGFQKGT-RQLLGSRTQLEL-----VLAGASLLLAALLLGCLVALGVQYHR 87
GGA ++ GF G R G+R+ L V + L+ AA L L A+ +
Sbjct: 26 GGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYL 85
Query: 88 DP--SHSTCLTEAC------IRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRS 139
P + E C R A + +LD + PC+DFY F+CGGW+RR+ +PD +
Sbjct: 86 GPVAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKL 145
Query: 140 RWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLI 199
+ T ++ +QN+ L+ LL A++K + F+ SCL + IE LG +P+ ++I
Sbjct: 146 TYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVI 205
Query: 200 EKIGGWNITGP---------WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQ 250
E GGW++ G WD + +L G Y A F++ +S D ++S+ VI+
Sbjct: 206 EDCGGWDLGGAEERPGVAARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIR 262
Query: 251 VDQSGLFLPSRDYYLNRTAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQL 309
+DQ GL LP R YL + + EK+L AY +ME + LLG + ++ Q++L++E QL
Sbjct: 263 IDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQL 320
Query: 310 ANITVPQ--DQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGM 367
ANITV + D RRD +Y+K+++ +LQ + P + W L + + S+ E VV+
Sbjct: 321 ANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLAT 379
Query: 368 DYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRW 427
DY+QQVS+LI T +L+NYL+W +V + L F A +L + + G+ K
Sbjct: 380 DYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELA 438
Query: 428 QTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQA 487
+ C+ + G ALG+LFV F SK + ++ +I+ + L +L WMD +TR A
Sbjct: 439 RVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAA 498
Query: 488 AKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKP 547
A+ K + M+G+PDF+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+
Sbjct: 499 ARAKLQYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQE 557
Query: 548 PSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHA 607
+ W + PQ +NAYYLP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH
Sbjct: 558 VDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHG 617
Query: 608 FDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADN 667
+DD G +YD+ GNL WW S + F C+ Y+ + V +R+NG+ TLGENIAD
Sbjct: 618 YDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADM 677
Query: 668 GGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPH 727
GGLK AY+AY+ W+R+HG E LP + T+ QLFF+ FAQ WC R +S + ++TD H
Sbjct: 678 GGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
Query: 728 SPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
+P +RVLG++S +F R F CP SPMNP C VW
Sbjct: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 57 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 116
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 117 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 176
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 177 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 230
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 231 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 290
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 291 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 338
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 339 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 396
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 397 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 456
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 457 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 515
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 516 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 575
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 576 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 635
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 636 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 692
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 693 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 752
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 753 GSPMNPGQLCEVW 765
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 57 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 116
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 117 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 176
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 177 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 230
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 231 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 290
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 291 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 338
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 339 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 396
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 397 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 456
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 457 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 515
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 516 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 575
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 576 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 635
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 636 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 692
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 693 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 752
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 753 GSPMNPGQLCEVW 765
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 57 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 116
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 117 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 176
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 177 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 230
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 231 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 290
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 291 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 338
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 339 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 396
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 397 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 456
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 457 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 515
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 516 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 575
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 576 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 635
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 636 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 692
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 693 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 752
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 753 GSPMNPGQLCEVW 765
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 57 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 116
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 117 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 176
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 177 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 230
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 231 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 290
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 291 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 338
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 339 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 396
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 397 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 456
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 457 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 515
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 516 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 575
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 576 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 635
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 636 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 692
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 693 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 752
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 753 GSPMNPGQLCEVW 765
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|90403592 phosphate-regulating neutral endopeptidase [Homo
sapiens]
Length = 749
Score = 459 bits (1182), Expect = e-129
Identities = 262/746 (35%), Positives = 407/746 (54%), Gaps = 32/746 (4%)
Query: 46 QKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGK 105
+ G + G+R L +V G +L+L +L LV+ G+ CL CI A
Sbjct: 10 ETGKKANRGTRIAL-VVFVGGTLVLGTILF--LVSQGL-LSLQAKQEYCLKPECIEAAAA 65
Query: 106 ILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT-TF 164
IL ++ V PC++F++F+C GWI NP+P+ + + L LK LLE + +
Sbjct: 66 ILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISR 125
Query: 165 NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG-GWNIT-------GPWDQDNF 216
+EA QK + Y SC+ + IE+ A+PL ++ W + G W + F
Sbjct: 126 RRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKF 185
Query: 217 --MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYL-NRTANEKV 273
++ L G Y + F +Y+S D K+SN +++++DQ+ L L R+ YL N T +
Sbjct: 186 SLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSY 245
Query: 274 LTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISE 333
A +M + +LLG + M+ VL LEI++A I +P + R E +Y+KM+ISE
Sbjct: 246 RDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEA-MYNKMNISE 304
Query: 334 LQALAPSMDWLEFLSFLLSPL------ELSDSEPVVVYGMDYLQQVSELINRTEPSILNN 387
L A+ P DWL ++ ++ ++S SE VVV Y + + ++ + N
Sbjct: 305 LSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIAN 364
Query: 388 YLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFV 447
YL+W +V +L RRF+ + + GT + +P+W C++ + AL + +G +FV
Sbjct: 365 YLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTT-TLLPQWDKCVNFIESALPYVVGKMFV 423
Query: 448 KATFDRQSKEIAEGMISEIRTAFEEALG-QLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 506
F KE+ E ++ +R AF + L + WMD T++ AKEKA A+ +G+P+FI+
Sbjct: 424 DVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIM 483
Query: 507 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 566
+++ + SE +F N+L + A+ LRK + +W P TVNA+Y
Sbjct: 484 NDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSA 543
Query: 567 TKNEIVFPAGILQAPFY-ARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWW 625
+ N+I FPAG LQ PF+ +P++L++G IGV++GHE TH FD+ GR+YDK GNL PWW
Sbjct: 544 STNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWW 603
Query: 626 QNESLAAFRNHTACMEEQYNQY--QVNGERLNGRQTLGENIADNGGLKAAYNAYKAWL-- 681
ES F+ T CM QY+ Y + G + G++TLGENIADNGGL+ A+ AY+ W+
Sbjct: 604 STESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWIND 663
Query: 682 RKHG-EEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSN 740
R+ G EE LP + TN+QLFF+ +A V C+ PE++ E + HSP +FRV G +SN
Sbjct: 664 RRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISN 723
Query: 741 SRDFLRHFGCPVGSPMNPG-QLCEVW 765
+F + F CP S MN G C +W
Sbjct: 724 FEEFQKAFNCPPNSTMNRGMDSCRLW 749
>gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens]
Length = 732
Score = 359 bits (922), Expect = 5e-99
Identities = 224/718 (31%), Positives = 355/718 (49%), Gaps = 53/718 (7%)
Query: 68 LLLAALLLGCLVALGVQYH---RDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFS 124
+L A L+LG L+ V ++ C T C+ + L S + V+PC DF+ F+
Sbjct: 48 VLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFA 107
Query: 125 CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQV 184
CG N N+F L +N+ L+ +LE E+K +FY SC+
Sbjct: 108 CGRAKETN---------NSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDT 158
Query: 185 ERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSS 244
IE G PLR +IE++GGW I+G W NF L+ + Y PFF Y+ S
Sbjct: 159 LAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASP 218
Query: 245 NSNVIQVDQSGLFLPSRDYYLNRTANEK----VLTAYLDYMEELGMLLGGRPTSTREQMQ 300
++ VIQ+DQ P D L + +K + YL Y+ +LG LLGG P+ +E
Sbjct: 219 HTPVIQIDQ-----PEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSS 273
Query: 301 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 360
+ + +L P +QRR + K++ ++I +L+ +AP++DWL L +P+ LS S+
Sbjct: 274 LSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQ 333
Query: 361 PVVVYGMDYLQQVSELINR---TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLY 417
+VV+ ++YL+ +S+L+ + L +++I LV + +LD +F+ A+ KL + L
Sbjct: 334 SLVVHDVEYLKNMSQLVEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLR 393
Query: 418 GTKKS----CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 473
+ PRW C+ T L +LFV+ F ++ A + + IR A
Sbjct: 394 ELTEQPPMPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITR 453
Query: 474 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 533
L L WM+E+T+ A++K + +G ++ L+P+ Y+ ++ SF Q++L+
Sbjct: 454 LRNLPWMNEETQNMAQDKVAQLQVEMGASEWALKPELARQEYNDIQLG-SSFLQSVLSCV 512
Query: 534 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 593
+ +P + +W ++P VNAYY + + +VFPAG+LQ PF+ +P+A+NF
Sbjct: 513 RSLRARIVQSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNF 572
Query: 594 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHT-----ACMEEQYNQYQ 648
G G +M HEL H F L P A NH C++ Y +
Sbjct: 573 GAAGSIMAHELLHIFYQL---------LLP----GGCLACDNHALQEAHLCLKRHYAAFP 619
Query: 649 V-NGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQ 707
+ + N T EN AD GGL A AY L +H E LP++ L+ Q+FF +AQ
Sbjct: 620 LPSRTSFNDSLTFLENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQ 679
Query: 708 VWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
V C +P+ SH D HSP RV G LS++ F R+F C G+ +NP C++W
Sbjct: 680 VMCRKPSPQDSH-----DTHSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW 732
>gi|40255251 hypothetical protein LOC131408 [Homo sapiens]
Length = 335
Score = 33.1 bits (74), Expect = 0.99
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 16/138 (11%)
Query: 5 LQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLELVLA 64
LQ+L G + R + PE+ SPD + LLGS +L L
Sbjct: 189 LQDLFTGHR---FSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLL 245
Query: 65 GASLLLAAL---LLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFY 121
G LLLA L +LG +D +++ LTE+C+ A + +PC+D
Sbjct: 246 GDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPA-------EEEPAPCKDCQ 298
Query: 122 QFS---CGGWIRRNPLPD 136
G W R+ D
Sbjct: 299 PLCPPLTGSWERQRQASD 316
>gi|124487387 ring finger protein 207 [Homo sapiens]
Length = 634
Score = 32.7 bits (73), Expect = 1.3
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 463 ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIG-FPDFILEPKE--LDDVYDGYE 519
+ ++TA EA+ L M E+ R +A E+ DAI+ + G D + E K L V YE
Sbjct: 211 VKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYE 270
Query: 520 ISEDSFFQNMLNL 532
+ +F + + +L
Sbjct: 271 EKDKAFKEQLSHL 283
>gi|239753431 PREDICTED: similar to endothelin converting
enzyme-like 1 [Homo sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 382 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 441
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 442 LGSLFV 447
L +LFV
Sbjct: 72 LRALFV 77
>gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 382 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 441
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 442 LGSLFV 447
L +LFV
Sbjct: 72 LRALFV 77
>gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 382 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 441
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 442 LGSLFV 447
L +LFV
Sbjct: 72 LRALFV 77
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 31.2 bits (69), Expect = 3.8
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 662 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 703
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
>gi|83641876 serine carboxypeptidase vitellogenic-like [Homo
sapiens]
Length = 476
Score = 30.0 bits (66), Expect = 8.4
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Query: 470 FEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNM 529
+ E L Q+ +DEK ++ +++ + I ++ + LD + DG S+ S+FQN+
Sbjct: 249 YAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNV 308
Query: 530 L---NLYNF 535
N YNF
Sbjct: 309 TGCSNYYNF 317
>gi|83641874 serine carboxypeptidase vitellogenic-like [Homo
sapiens]
Length = 476
Score = 30.0 bits (66), Expect = 8.4
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Query: 470 FEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNM 529
+ E L Q+ +DEK ++ +++ + I ++ + LD + DG S+ S+FQN+
Sbjct: 249 YAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNV 308
Query: 530 L---NLYNF 535
N YNF
Sbjct: 309 TGCSNYYNF 317
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 30.0 bits (66), Expect = 8.4
Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 468 TAFEEALGQLVWMDEKT---RQAAKEKADAIYD----MIGFPDFILEPKE--LDDVYDGY 518
T +AL QL ++ E T R + + D + D + FPDFI ++ L+ DG+
Sbjct: 133 TINHQALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGH 192
Query: 519 EISEDSFFQNMLNL 532
I+ED + +N L L
Sbjct: 193 PITEDEYLENALKL 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,432,928
Number of Sequences: 37866
Number of extensions: 1337341
Number of successful extensions: 3214
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3120
Number of HSP's gapped (non-prelim): 28
length of query: 765
length of database: 18,247,518
effective HSP length: 110
effective length of query: 655
effective length of database: 14,082,258
effective search space: 9223878990
effective search space used: 9223878990
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.