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Search of human proteins with 153792268
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792268 G protein-coupled receptor 31 [Homo sapiens]
(319 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792268 G protein-coupled receptor 31 [Homo sapiens] 643 0.0
gi|157738694 G protein-coupled receptor 109B [Homo sapiens] 191 7e-49
gi|29171311 G protein-coupled receptor 109A [Homo sapiens] 189 4e-48
gi|14211851 G protein-coupled receptor 81 [Homo sapiens] 174 9e-44
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] 166 3e-41
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 124 1e-28
gi|167000885 galanin receptor 1 [Homo sapiens] 124 1e-28
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 121 9e-28
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 121 9e-28
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 121 9e-28
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 121 9e-28
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 120 1e-27
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 120 1e-27
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 120 1e-27
gi|47271392 succinate receptor 1 [Homo sapiens] 117 1e-26
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 115 7e-26
gi|149944554 somatostatin receptor 4 [Homo sapiens] 112 4e-25
gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens] 112 6e-25
gi|156104886 CC chemokine receptor 10 [Homo sapiens] 111 1e-24
gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens] 109 4e-24
gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens] 109 4e-24
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 108 5e-24
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 108 5e-24
gi|4503905 galanin receptor 2 [Homo sapiens] 107 1e-23
gi|4557865 somatostatin receptor 5 [Homo sapiens] 106 2e-23
gi|4557861 somatostatin receptor 3 [Homo sapiens] 106 3e-23
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 105 4e-23
gi|4502641 chemokine (C-C motif) receptor 7 precursor [Homo sapi... 105 4e-23
gi|4504681 interleukin 8 receptor alpha [Homo sapiens] 105 5e-23
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 105 7e-23
>gi|153792268 G protein-coupled receptor 31 [Homo sapiens]
Length = 319
Score = 643 bits (1659), Expect = 0.0
Identities = 319/319 (100%), Positives = 319/319 (100%)
Query: 1 MPFPNCSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALAD 60
MPFPNCSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALAD
Sbjct: 1 MPFPNCSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALAD 60
Query: 61 LLLAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPR 120
LLLAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPR
Sbjct: 61 LLLAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPR 120
Query: 121 LKVNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEA 180
LKVNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEA
Sbjct: 121 LKVNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEA 180
Query: 181 LSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFL 240
LSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFL
Sbjct: 181 LSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFL 240
Query: 241 ARVLMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL 300
ARVLMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL
Sbjct: 241 ARVLMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL 300
Query: 301 RGKGQAAEPPDFNPRDSYS 319
RGKGQAAEPPDFNPRDSYS
Sbjct: 301 RGKGQAAEPPDFNPRDSYS 319
>gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
Length = 387
Score = 191 bits (485), Expect = 7e-49
Identities = 113/317 (35%), Positives = 169/317 (53%), Gaps = 27/317 (8%)
Query: 6 CSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAA 65
C +A + +LGLE GLLGN +ALW F F ++ WK ++L NLA+AD LL
Sbjct: 19 CVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78
Query: 66 CLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNL 125
CLPF+ +Y+ W G + C + F+ ++R + FL VA+DRY RVVHP +N
Sbjct: 79 CLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138
Query: 126 LSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTR--------CHSFYSRADGSFSIIW 177
+S A +S L+W + V LT L QN T CH+F W
Sbjct: 139 ISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFR----------W 188
Query: 178 QEALSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLP 237
EA+ L+F LP G+I+FC+A II +L R R+ ++ K++RA + +V ++F +CFLP
Sbjct: 189 HEAMFLLEFFLPLGIILFCSARIIWSL--RQRQMDRHAKIKRAITFIMVVAIVFVICFLP 246
Query: 238 CFLARVLMHIF-----QNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSS 292
+ R+ HIF +C +V +T S TY++S+L+PVVY FSSP+F +
Sbjct: 247 SVVVRI--HIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304
Query: 293 YRRVFHTLRGKGQAAEP 309
+ + + + EP
Sbjct: 305 FSTLINRCLQRKITGEP 321
>gi|29171311 G protein-coupled receptor 109A [Homo sapiens]
Length = 363
Score = 189 bits (479), Expect = 4e-48
Identities = 110/296 (37%), Positives = 166/296 (56%), Gaps = 13/296 (4%)
Query: 20 LLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQA 79
+LGLE GLLGN +ALW F F ++ WK ++L NLA+AD LL CLPFL Y+
Sbjct: 33 VLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWD 92
Query: 80 WHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVW 139
W G + C + F+L ++R + FL VA+DRY RVVHP +N +S + A +S L+W
Sbjct: 93 WKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLW 152
Query: 140 LLMVALTCPGLLISEAAQN--STRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCN 197
+ + LT L QN + C SF + W EA+ L+F LP G+I+FC+
Sbjct: 153 GITIGLTVHLLKKKMPIQNGGANLCSSF----SICHTFQWHEAMFLLEFFLPLGIILFCS 208
Query: 198 AGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARV----LMHIFQNLGS 253
A II +L R R+ ++ K++RA + +V ++F +CFLP + R+ L+H +
Sbjct: 209 ARIIWSL--RQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHT-SGTQN 265
Query: 254 CRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEP 309
C +V +T S TY++S+L+PVVY FSSP+F + + + + + EP
Sbjct: 266 CEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321
>gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
Length = 346
Score = 174 bits (441), Expect = 9e-44
Identities = 99/293 (33%), Positives = 160/293 (54%), Gaps = 9/293 (3%)
Query: 6 CSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAA 65
C ++ + LL + LG LGN VAL F F ++ WKP VYL NLA+AD LL
Sbjct: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
Query: 66 CLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNL 125
CLPF +YL + W G + C F L ++R+ + FL VA DRY +VVHP VN
Sbjct: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
Query: 126 LSPQAALGVSGLVWLLMVALTCPGLLISE--AAQNSTRCHSFYSRADGSFSIIWQEALSC 183
+S + A G+ +W L++ T LL + + + C SF + W + +
Sbjct: 127 ISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANG----WHDIMFQ 182
Query: 184 LQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARV 243
L+F +P G+I+FC+ I+ +L++R ++ +Q ++++A + +V ++F C+LP AR
Sbjct: 183 LEFFMPLGIILFCSFKIVWSLRRR-QQLARQARMKKATRFIMVVAIVFITCYLPSVSAR- 240
Query: 244 LMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRV 296
++ + S +V +T S TY++S+L+P+VY FSSP+F Y ++
Sbjct: 241 -LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKL 292
>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
Length = 423
Score = 166 bits (419), Expect = 3e-41
Identities = 104/306 (33%), Positives = 164/306 (53%), Gaps = 6/306 (1%)
Query: 10 STVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPF 69
S++V+ + +L LE LGL+GN++AL+ F R W V+L++L AD LL + LP
Sbjct: 88 SSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPL 147
Query: 70 LAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQ 129
+YL + W G C F+L +R+ + FL A+AL+RYL+VV P ++ S
Sbjct: 148 RVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVG 207
Query: 130 AALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLP 189
AA V+G +W+ ++ L LL+S + S C S+ S S+ W +AL L+F LP
Sbjct: 208 AAARVAGGLWVGILLLN-GHLLLSTFSGPS--CLSYRVGTKPSASLRWHQALYLLEFFLP 264
Query: 190 FGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQ 249
LI+F I ++ R + P QRA ++ +VV ++ +CFLP + + +
Sbjct: 265 LALILFAIVSIGLTIRNRGLGGQAGP--QRAMRVLAMVVAVYTICFLPSIIFGMASMVAF 322
Query: 250 NLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGK-GQAAE 308
L +CR+L + + TYL+SVL+PV+YCFSSP F R + RG+ G ++
Sbjct: 323 WLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSD 382
Query: 309 PPDFNP 314
+ P
Sbjct: 383 ESSYQP 388
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 124 bits (310), Expect = 1e-28
Identities = 80/287 (27%), Positives = 134/287 (46%), Gaps = 9/287 (3%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVG 86
+G LGN+VA+W F+F ++ W +VY+ NLALAD L LP L +Y + W G
Sbjct: 64 IGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAM 123
Query: 87 CWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALT 146
C F+ ++ + FL ++ RY VV+P + L + A+ +S LVWL++V
Sbjct: 124 CKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAI 183
Query: 147 CPGLLISEAAQNSTRCHSFYSRADGSF---SIIWQEALSCLQFVLPFGLIVFCNAGIIRA 203
P L S + + Y + I+ + F +P LI+ C I+RA
Sbjct: 184 SPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRA 243
Query: 204 LQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVL----MHIFQNLGSCRALCA 259
L ++ + P +++ LV +V+ +FA+ ++P + + + FQ C
Sbjct: 244 L--IYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDR 301
Query: 260 VAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQA 306
V T VT L L+S ++P++Y + TFR R + +A
Sbjct: 302 VYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEA 348
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 124 bits (310), Expect = 1e-28
Identities = 93/290 (32%), Positives = 148/290 (51%), Gaps = 20/290 (6%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYA---VYLLNLALADLL-LAACLPFLAAFY 74
V+ GL LG+LGN++ + T L R + KP + +++LNL++ADL L C+PF A Y
Sbjct: 38 VVFGLIFALGVLGNSLVI-TVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVY 96
Query: 75 LSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNL-LSPQAALG 133
+L W LG C +H+ +S V + LAA+++DRY+ +VH R +L +S A LG
Sbjct: 97 -ALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLG 155
Query: 134 VSGLVWLLMVALTCPGL----LISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLP 189
V G +W L +A+ P L A N T C + D + ++LP
Sbjct: 156 V-GCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQW--PDPRHKKAYVVCTFVFGYLLP 212
Query: 190 FGLIVFCNAGIIRALQKRLREPEKQPKLQRAQA--LVTLVVVLFALCFLPCFLARVLMHI 247
LI FC A ++ L K+L+ K+ + + + V +VVV+F + +LP ++H+
Sbjct: 213 LLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLP----HHIIHL 268
Query: 248 FQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVF 297
+ G A L Y +S +NP++Y F S FR +Y++VF
Sbjct: 269 WAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVF 318
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 121 bits (303), Expect = 9e-28
Identities = 84/297 (28%), Positives = 143/297 (48%), Gaps = 13/297 (4%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVG 86
L L+GN +ALW F+ + P V+L++LA+ADL LP ++ S W G +
Sbjct: 44 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 103
Query: 87 CWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALT 146
C FL L+ + FL ++ DR+L +VHP + L P A +W+++
Sbjct: 104 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 163
Query: 147 CPGLLISEAAQ--NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRAL 204
P L+ + Q ++ C Y +++ + F PF V C IIR+L
Sbjct: 164 APLLVSPQTVQTNHTVVCLQLYREKASHHALV----SLAVAFTFPFITTVTCYLLIIRSL 219
Query: 205 QKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLAR--VLMHIFQNLGSCRALCAVAH 262
++ LR EK+ K +A ++ +V+ +F +CF+P + R ++H + SC +A
Sbjct: 220 RQGLR-VEKRLK-TKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILAL 277
Query: 263 TSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS 319
+ +T LT L+ L+P++Y F + FR + + + L GK PP F + + S
Sbjct: 278 ANRITSCLTSLNGALDPIMYFFVAEKFRHA---LCNLLCGKRLKGPPPSFEGKTNES 331
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 121 bits (303), Expect = 9e-28
Identities = 84/297 (28%), Positives = 143/297 (48%), Gaps = 13/297 (4%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVG 86
L L+GN +ALW F+ + P V+L++LA+ADL LP ++ S W G +
Sbjct: 44 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 103
Query: 87 CWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALT 146
C FL L+ + FL ++ DR+L +VHP + L P A +W+++
Sbjct: 104 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 163
Query: 147 CPGLLISEAAQ--NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRAL 204
P L+ + Q ++ C Y +++ + F PF V C IIR+L
Sbjct: 164 APLLVSPQTVQTNHTVVCLQLYREKASHHALV----SLAVAFTFPFITTVTCYLLIIRSL 219
Query: 205 QKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLAR--VLMHIFQNLGSCRALCAVAH 262
++ LR EK+ K +A ++ +V+ +F +CF+P + R ++H + SC +A
Sbjct: 220 RQGLR-VEKRLK-TKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILAL 277
Query: 263 TSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS 319
+ +T LT L+ L+P++Y F + FR + + + L GK PP F + + S
Sbjct: 278 ANRITSCLTSLNGALDPIMYFFVAEKFRHA---LCNLLCGKRLKGPPPSFEGKTNES 331
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 121 bits (303), Expect = 9e-28
Identities = 84/297 (28%), Positives = 143/297 (48%), Gaps = 13/297 (4%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVG 86
L L+GN +ALW F+ + P V+L++LA+ADL LP ++ S W G +
Sbjct: 72 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 131
Query: 87 CWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALT 146
C FL L+ + FL ++ DR+L +VHP + L P A +W+++
Sbjct: 132 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 191
Query: 147 CPGLLISEAAQ--NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRAL 204
P L+ + Q ++ C Y +++ + F PF V C IIR+L
Sbjct: 192 APLLVSPQTVQTNHTVVCLQLYREKASHHALV----SLAVAFTFPFITTVTCYLLIIRSL 247
Query: 205 QKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLAR--VLMHIFQNLGSCRALCAVAH 262
++ LR EK+ K +A ++ +V+ +F +CF+P + R ++H + SC +A
Sbjct: 248 RQGLR-VEKRLK-TKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILAL 305
Query: 263 TSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS 319
+ +T LT L+ L+P++Y F + FR + + + L GK PP F + + S
Sbjct: 306 ANRITSCLTSLNGALDPIMYFFVAEKFRHA---LCNLLCGKRLKGPPPSFEGKTNES 359
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 121 bits (303), Expect = 9e-28
Identities = 84/297 (28%), Positives = 143/297 (48%), Gaps = 13/297 (4%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVG 86
L L+GN +ALW F+ + P V+L++LA+ADL LP ++ S W G +
Sbjct: 72 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 131
Query: 87 CWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALT 146
C FL L+ + FL ++ DR+L +VHP + L P A +W+++
Sbjct: 132 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 191
Query: 147 CPGLLISEAAQ--NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRAL 204
P L+ + Q ++ C Y +++ + F PF V C IIR+L
Sbjct: 192 APLLVSPQTVQTNHTVVCLQLYREKASHHALV----SLAVAFTFPFITTVTCYLLIIRSL 247
Query: 205 QKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLAR--VLMHIFQNLGSCRALCAVAH 262
++ LR EK+ K +A ++ +V+ +F +CF+P + R ++H + SC +A
Sbjct: 248 RQGLR-VEKRLK-TKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILAL 305
Query: 263 TSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS 319
+ +T LT L+ L+P++Y F + FR + + + L GK PP F + + S
Sbjct: 306 ANRITSCLTSLNGALDPIMYFFVAEKFRHA---LCNLLCGKRLKGPPPSFEGKTNES 359
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 120 bits (302), Expect = 1e-27
Identities = 85/269 (31%), Positives = 130/269 (48%), Gaps = 5/269 (1%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQ 78
V G+ C GL NAVAL+ FL R++ W Y+ +LA++D L AA LP L +Y
Sbjct: 38 VSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGD 97
Query: 79 AWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLV 138
W V C + FL + + FL +++ R L V+ P + + A V+G V
Sbjct: 98 HWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAV 157
Query: 139 WLLMVALTCPGL--LISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFC 196
W+L++A P L + + A CH + S + + + L F +PF +I+ C
Sbjct: 158 WVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVC 217
Query: 197 NAGIIRALQKRLREPEKQPKLQRAQALVTLVVVL--FALCFLPCFLARVLMHIFQNLG-S 253
+ R L K + +++ T+ VVL FALCFLP + R L + F++L S
Sbjct: 218 YVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLS 277
Query: 254 CRALCAVAHTSDVTGSLTYLHSVLNPVVY 282
C L A+ VT L +S L+PV+Y
Sbjct: 278 CHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 120 bits (302), Expect = 1e-27
Identities = 85/269 (31%), Positives = 130/269 (48%), Gaps = 5/269 (1%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQ 78
V G+ C GL NAVAL+ FL R++ W Y+ +LA++D L AA LP L +Y
Sbjct: 38 VSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGD 97
Query: 79 AWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLV 138
W V C + FL + + FL +++ R L V+ P + + A V+G V
Sbjct: 98 HWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAV 157
Query: 139 WLLMVALTCPGL--LISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFC 196
W+L++A P L + + A CH + S + + + L F +PF +I+ C
Sbjct: 158 WVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVC 217
Query: 197 NAGIIRALQKRLREPEKQPKLQRAQALVTLVVVL--FALCFLPCFLARVLMHIFQNLG-S 253
+ R L K + +++ T+ VVL FALCFLP + R L + F++L S
Sbjct: 218 YVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLS 277
Query: 254 CRALCAVAHTSDVTGSLTYLHSVLNPVVY 282
C L A+ VT L +S L+PV+Y
Sbjct: 278 CHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 120 bits (302), Expect = 1e-27
Identities = 85/269 (31%), Positives = 130/269 (48%), Gaps = 5/269 (1%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQ 78
V G+ C GL NAVAL+ FL R++ W Y+ +LA++D L AA LP L +Y
Sbjct: 38 VSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGD 97
Query: 79 AWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLV 138
W V C + FL + + FL +++ R L V+ P + + A V+G V
Sbjct: 98 HWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAV 157
Query: 139 WLLMVALTCPGL--LISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFC 196
W+L++A P L + + A CH + S + + + L F +PF +I+ C
Sbjct: 158 WVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVC 217
Query: 197 NAGIIRALQKRLREPEKQPKLQRAQALVTLVVVL--FALCFLPCFLARVLMHIFQNLG-S 253
+ R L K + +++ T+ VVL FALCFLP + R L + F++L S
Sbjct: 218 YVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLS 277
Query: 254 CRALCAVAHTSDVTGSLTYLHSVLNPVVY 282
C L A+ VT L +S L+PV+Y
Sbjct: 278 CHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|47271392 succinate receptor 1 [Homo sapiens]
Length = 334
Score = 117 bits (293), Expect = 1e-26
Identities = 81/280 (28%), Positives = 143/280 (51%), Gaps = 8/280 (2%)
Query: 17 VGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLS 76
+ + G+E +G+LGN + ++ ++F ++ W +YL NL+++DL LP L Y +
Sbjct: 26 LSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYAN 85
Query: 77 LQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSG 136
W G V C + ++L + + FL +++DRYL + +P + L + A+ +S
Sbjct: 86 GN-WIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISL 144
Query: 137 LVWLLMVALTCPGL-LISEA-AQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIV 194
+W+L+ P L LI+ N T C+ F S D ++++I+ L+ L F++P ++
Sbjct: 145 AIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMC 204
Query: 195 FCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNLGSC 254
F I L++R R+ L++ LV + VV+F++ F P + R + I LGS
Sbjct: 205 FFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMR-NVRIASRLGSW 263
Query: 255 RAL-CAVAHTSD---VTGSLTYLHSVLNPVVYCFSSPTFR 290
+ C + VT L +L+SV+NPV Y FR
Sbjct: 264 KQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFR 303
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 115 bits (287), Expect = 7e-26
Identities = 77/274 (28%), Positives = 126/274 (45%), Gaps = 5/274 (1%)
Query: 26 GLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRV 85
GLGL NA LW F+FR+R W A Y+ +LAL+D L LP L +Y + W G
Sbjct: 49 GLGL--NAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTE 106
Query: 86 GCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVAL 145
C + FL + + FL +++ RYL + HP + P+ A + VWL++
Sbjct: 107 ICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGC 166
Query: 146 TCPGLLISEAAQNSTR--CHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRA 203
P L + T CH + + + A+ L F +P + + C + R
Sbjct: 167 LVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARR 226
Query: 204 LQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNL-GSCRALCAVAH 262
L + L + R+ + +V+ +FA+CF+P + R + ++ + L CR L V
Sbjct: 227 LYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNV 286
Query: 263 TSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRV 296
VT L +S L+PV+Y + +R R++
Sbjct: 287 VYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQL 320
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 112 bits (280), Expect = 4e-25
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 18/304 (5%)
Query: 16 AVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYL 75
A+ + L C +GL+GNA+ ++ L ++ +YLLNLA+AD L +PF+A+
Sbjct: 49 AIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVAS-SA 107
Query: 76 SLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVS 135
+L+ W G V C A+ + L+ + L +++DRY+ VVHP P A ++
Sbjct: 108 ALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLIN 167
Query: 136 GLVWLLMVALTCPGLLISEA----AQNSTRCHSFYSR-ADGSFSIIWQEALSCLQFVLPF 190
VWL + +T P + ++ + C+ + A + +++ L L VL
Sbjct: 168 LGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAI 227
Query: 191 GLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQN 250
GL G +RA+ R +++ ++ LV +VVV+F LC++P ++ ++L N
Sbjct: 228 GLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLL-----N 282
Query: 251 LGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVF----HTLRGKGQA 306
L V H S + L+Y +S NP++Y F S FR ++RV L G G A
Sbjct: 283 LFVTSLDATVNHVSLI---LSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGA 339
Query: 307 AEPP 310
E P
Sbjct: 340 EEEP 343
>gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]
Length = 360
Score = 112 bits (279), Expect = 6e-25
Identities = 81/279 (29%), Positives = 131/279 (46%), Gaps = 11/279 (3%)
Query: 28 GLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVGC 87
GLLGN+V + R+ VYLLNLA++DLL LPF Y + W G C
Sbjct: 53 GLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWG--YYAADQWVFGLGLC 110
Query: 88 WALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALTC 147
+ ++ + G+ F+ +++DRYL +VH + + + S W + V +
Sbjct: 111 KMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASL 170
Query: 148 PGLLISE--AAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRALQ 205
PG L S +N T C + YS ++ ++ ++ L V+P G+++FC + IIR LQ
Sbjct: 171 PGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQ 230
Query: 206 KRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHI--FQNLGSCRALCAVAHT 263
K K +A ++ VVVLF + P + L + + L C + +
Sbjct: 231 HC-----KNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYA 285
Query: 264 SDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRG 302
T +L ++H LNP++Y F FR ++F T RG
Sbjct: 286 IQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRG 324
>gi|156104886 CC chemokine receptor 10 [Homo sapiens]
Length = 362
Score = 111 bits (277), Expect = 1e-24
Identities = 102/292 (34%), Positives = 135/292 (46%), Gaps = 34/292 (11%)
Query: 27 LGLLGNAVALWTFLFRVRVWK-PYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRV 85
LGL GN + L T L R + P + +LL LALADLLLA LPF AA +LQ W LG
Sbjct: 54 LGLAGNGLVLATHLAARRAARSPTSAHLLQLALADLLLALTLPFAAAG--ALQGWSLGSA 111
Query: 86 GCWALHFLLDLSRSVGMAFLAAVALDRYLRVVH-----PRLKVNLLSPQAALGVSGLVWL 140
C + L S G FLA ++ DRY+ + PR +P A VS +VWL
Sbjct: 112 TCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRPS----TPGRAHLVSVIVWL 167
Query: 141 LMVALTCPGLLISEAAQ--NSTRCHSFY----SRADGSFSIIWQEALSCLQFVLPFGLIV 194
L + L P LL S+ Q RC + ++ S + Q AL F LP G++V
Sbjct: 168 LSLLLALPALLFSQDGQREGQRRCRLIFPEGLTQTVKGASAVAQVALG---FALPLGVMV 224
Query: 195 FCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNLGSC 254
C A + R L + P+ +RA +V +V F + LP LA +L+ L +
Sbjct: 225 ACYALLGRTLL-----AARGPERRRALRVVVALVAAFVVLQLPYSLA-LLLDTADLLAAR 278
Query: 255 RALCAVAHTSD----VTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRG 302
C + D VT L LNPV+Y F FR RR+ LRG
Sbjct: 279 ERSCPASKRKDVALLVTSGLALARCGLNPVLYAFLGLRFRQDLRRL---LRG 327
>gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens]
Length = 374
Score = 109 bits (272), Expect = 4e-24
Identities = 85/297 (28%), Positives = 141/297 (47%), Gaps = 24/297 (8%)
Query: 17 VGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLS 76
V + L C GLLGN + + TF F + VYLLN+A+AD+L LPF A + +
Sbjct: 49 VPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSH-A 107
Query: 77 LQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLS---PQAALG 133
AW C L + ++ + GM L +++DRY+ +V L S P++ +
Sbjct: 108 TGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKI- 166
Query: 134 VSGLVWLLMVALTCPGLLISEA--AQNSTRCHSFYSRADGSFSIIWQEALSCLQ----FV 187
+ +VW L V ++ + ++ Q S C Y S I W+ + L+ F
Sbjct: 167 ICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTV--SEPIRWKLLMLGLELLFGFF 224
Query: 188 LPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHI 247
+P ++FC I++ L + + K +A ++ VV++F C +P + VL+
Sbjct: 225 IPLMFMIFCYTFIVKTLVQ-----AQNSKRHKAIRVIIAVVLVFLACQIPHNM--VLLVT 277
Query: 248 FQNLG----SCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL 300
NLG SC++ + +T VT L +LH LNPV+Y F FR+ + ++ L
Sbjct: 278 AANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDL 334
>gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens]
Length = 374
Score = 109 bits (272), Expect = 4e-24
Identities = 85/297 (28%), Positives = 141/297 (47%), Gaps = 24/297 (8%)
Query: 17 VGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLS 76
V + L C GLLGN + + TF F + VYLLN+A+AD+L LPF A + +
Sbjct: 49 VPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSH-A 107
Query: 77 LQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLS---PQAALG 133
AW C L + ++ + GM L +++DRY+ +V L S P++ +
Sbjct: 108 TGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKI- 166
Query: 134 VSGLVWLLMVALTCPGLLISEA--AQNSTRCHSFYSRADGSFSIIWQEALSCLQ----FV 187
+ +VW L V ++ + ++ Q S C Y S I W+ + L+ F
Sbjct: 167 ICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTV--SEPIRWKLLMLGLELLFGFF 224
Query: 188 LPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHI 247
+P ++FC I++ L + + K +A ++ VV++F C +P + VL+
Sbjct: 225 IPLMFMIFCYTFIVKTLVQ-----AQNSKRHKAIRVIIAVVLVFLACQIPHNM--VLLVT 277
Query: 248 FQNLG----SCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL 300
NLG SC++ + +T VT L +LH LNPV+Y F FR+ + ++ L
Sbjct: 278 AANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDL 334
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 108 bits (271), Expect = 5e-24
Identities = 86/316 (27%), Positives = 155/316 (49%), Gaps = 19/316 (6%)
Query: 10 STVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPF 69
STV+ T+ V+ + GL+GN +AL+ FL R +YLLN+A+ADLLL CLPF
Sbjct: 54 STVLTTSYSVIFIV----GLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPF 109
Query: 70 LAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQ 129
++++ W LG + C + L ++ + + L ++LDRY+++ + ++ +
Sbjct: 110 RIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTK 169
Query: 130 AALGVSGLVWLLMVA--LTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFV 187
++ V +VW+L + LT L + + NST C + + + I+ L + F
Sbjct: 170 QSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFIL-VVMFW 228
Query: 188 LPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVT------LVVVLFALCFLPCFLA 241
L F LI+ I+ + LR +++ K + T +V+++F +CF+P
Sbjct: 229 LIFLLIIL---SYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAF 285
Query: 242 RVLMHIFQ-NLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRS-SYRRVFHT 299
R + Q N+ SC V T+++ L+ +S L+PV+Y S R + +F
Sbjct: 286 RFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRR 345
Query: 300 LRGKGQAAE-PPDFNP 314
+G+ +E +F P
Sbjct: 346 FQGEPSRSESTSEFKP 361
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 108 bits (271), Expect = 5e-24
Identities = 86/316 (27%), Positives = 155/316 (49%), Gaps = 19/316 (6%)
Query: 10 STVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPF 69
STV+ T+ V+ + GL+GN +AL+ FL R +YLLN+A+ADLLL CLPF
Sbjct: 54 STVLTTSYSVIFIV----GLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPF 109
Query: 70 LAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQ 129
++++ W LG + C + L ++ + + L ++LDRY+++ + ++ +
Sbjct: 110 RIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTK 169
Query: 130 AALGVSGLVWLLMVA--LTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFV 187
++ V +VW+L + LT L + + NST C + + + I+ L + F
Sbjct: 170 QSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFIL-VVMFW 228
Query: 188 LPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVT------LVVVLFALCFLPCFLA 241
L F LI+ I+ + LR +++ K + T +V+++F +CF+P
Sbjct: 229 LIFLLIIL---SYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAF 285
Query: 242 RVLMHIFQ-NLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRS-SYRRVFHT 299
R + Q N+ SC V T+++ L+ +S L+PV+Y S R + +F
Sbjct: 286 RFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRR 345
Query: 300 LRGKGQAAE-PPDFNP 314
+G+ +E +F P
Sbjct: 346 FQGEPSRSESTSEFKP 361
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 107 bits (268), Expect = 1e-23
Identities = 94/297 (31%), Positives = 139/297 (46%), Gaps = 15/297 (5%)
Query: 14 ATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADL-LLAACLPFLAA 72
A V +L L +G +GN + L L + +++LNL +ADL + C+PF A
Sbjct: 25 AVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQAT 84
Query: 73 FYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAAL 132
Y +L W G + C A+HFL+ L+ LAAV+LDRYL + +P L +P+ AL
Sbjct: 85 IY-TLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNAL 143
Query: 133 GVSGLVWLLMVALTCPGLLISEAAQ--NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPF 190
GL+W L + + P L +Q N T CH +S I S L VL
Sbjct: 144 AAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVL 203
Query: 191 GLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVT----LVVVLFALCFLPCFLARVLMH 246
GL A +R L + + +RA+ VT +V LF LC++P A +L
Sbjct: 204 GLTY---ARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMP-HHALILCV 259
Query: 247 IFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGK 303
F RA A+ S + ++Y +S +NP+VY S FR +R + L G+
Sbjct: 260 WFGQFPLTRATYALRILSHL---VSYANSCVNPIVYALVSKHFRKGFRTICAGLLGR 313
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 106 bits (265), Expect = 2e-23
Identities = 91/314 (28%), Positives = 149/314 (47%), Gaps = 31/314 (9%)
Query: 14 ATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAF 73
A V VL L C GL GN + ++ L ++ +Y+LNLA+AD+L LPFLA
Sbjct: 40 AVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLAT- 98
Query: 74 YLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALG 133
+ W G V C + L +++ + L +++DRYL VVHP P+ A
Sbjct: 99 QNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKL 158
Query: 134 VSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLI 193
S W+L + ++ P L+ ++ + T C++ + G + ++ + L F P +I
Sbjct: 159 ASAAAWVLSLCMSLPLLVFADVQEGGT-CNASWPEPVGLWGAVFIIYTAVLGFFAPLLVI 217
Query: 194 VFCNAGI---IRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQN 250
C I +RA R+ ++ + ++ +V +VV++FA C+LP F ++ N
Sbjct: 218 CLCYLLIVVKVRAAGVRVGCVRRRSE-RKVTRMVLVVVLVFAGCWLPFFTVNIV-----N 271
Query: 251 LGSCRALCAVAHTSDVTGS--------LTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRG 302
L AVA + + L+Y +S NPV+Y F S FR S+++V +G
Sbjct: 272 L-------AVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKG 324
Query: 303 KG----QAAEP-PD 311
G A EP PD
Sbjct: 325 SGAKDADATEPRPD 338
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 106 bits (264), Expect = 3e-23
Identities = 86/319 (26%), Positives = 142/319 (44%), Gaps = 27/319 (8%)
Query: 7 SAPSTVVATAVGVLLGLE----CGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLL 62
+ PS GVL+ L C +GLLGN++ ++ L VY+LNLALAD L
Sbjct: 33 AGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADEL 92
Query: 63 LAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLK 122
LPFLAA +L W G + C + + +++ + L +++DRYL VVHP
Sbjct: 93 FMLGLPFLAA-QNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRS 151
Query: 123 VNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALS 182
+ A VS VW+ + P ++ S + + CH + ++ + +
Sbjct: 152 ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTA 211
Query: 183 CLQFVLPFGLIVFCNAGI---IRALQKRLREPEKQPKL---QRAQALVTLVVVLFALCFL 236
L F P +I C I +R+ +R+ P Q + +R +V VV LF LC++
Sbjct: 212 ALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWM 271
Query: 237 PCFLARVLMHIFQNLGSCRALCAVAHTSDVTG------SLTYLHSVLNPVVYCFSSPTFR 290
P ++ ++ +C + G +L Y +S NP++Y F S F+
Sbjct: 272 PFYVLNIV----------NVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFK 321
Query: 291 SSYRRVFHTLRGKGQAAEP 309
+RRV + ++ EP
Sbjct: 322 QGFRRVLLRPSRRVRSQEP 340
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 105 bits (263), Expect = 4e-23
Identities = 84/291 (28%), Positives = 145/291 (49%), Gaps = 16/291 (5%)
Query: 28 GLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVGC 87
G+LGN ++++ FL + V++LNLA++DLL + LPF A +YL W G + C
Sbjct: 52 GVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLAC 111
Query: 88 WALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALTC 147
+ + L ++ + FL +++ R+L +VHP +++ S ++A + G++W+L++A +
Sbjct: 112 RIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSI 171
Query: 148 PGLLISEAAQNS--TRC--HSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRA 203
LL S + QN T C + Y A + CL LPF + C IIR
Sbjct: 172 M-LLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCL---LPFFTLSICYLLIIRV 227
Query: 204 LQKRLREPEKQPKLQRAQALVTLVV--VLFALCFLPCFLARVLMHIFQNLGSCRALCAVA 261
L K + PE ++ +AL T+++ ++F LCFLP R + +G C+ A
Sbjct: 228 LLK-VEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKA 286
Query: 262 HTSDVTGSLTYLHSVLNPVVYCFSSPTFR---SSYRRVFHTLRGKGQAAEP 309
+T +L ++ NP++Y F+ F+ S R H + K + P
Sbjct: 287 LV--ITLALAAANACFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFP 335
>gi|4502641 chemokine (C-C motif) receptor 7 precursor [Homo
sapiens]
Length = 378
Score = 105 bits (263), Expect = 4e-23
Identities = 85/293 (29%), Positives = 141/293 (48%), Gaps = 22/293 (7%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQ 78
++ + C +GLLGN + + T+++ R+ YLLNLA+AD+L LPF A Y + +
Sbjct: 63 IMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWA--YSAAK 120
Query: 79 AWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHP------RLKVNLLSPQAAL 132
+W G C + + +S GM L +++DRY+ +V R +V L+S + +
Sbjct: 121 SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV 180
Query: 133 GVSGLVWLLMVALTCPGLLISEAAQNST----RCHSFYSRADGSFSIIWQEALSCLQFVL 188
G +W+L L+ P LL S+ ++S+ RC + +I Q A + F++
Sbjct: 181 G----IWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITI--QVAQMVIGFLV 234
Query: 189 PFGLIVFCNAGIIRA-LQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHI 247
P + FC IIR LQ R E K K+ A V +V ++F L + LA+ + +
Sbjct: 235 PLLAMSFCYLVIIRTLLQARNFERNKAIKVIIA---VVVVFIVFQLPYNGVVLAQTVANF 291
Query: 248 FQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTL 300
+C + DVT SL + +NP +Y F FR+ ++F L
Sbjct: 292 NITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDL 344
>gi|4504681 interleukin 8 receptor alpha [Homo sapiens]
Length = 350
Score = 105 bits (262), Expect = 5e-23
Identities = 82/277 (29%), Positives = 126/277 (45%), Gaps = 16/277 (5%)
Query: 27 LGLLGNAVALWTFLFRVRVWKPYA-VYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRV 85
L LLGN++ + L+ RV + VYLLNLALADLL A LP AA + W G
Sbjct: 52 LSLLGNSLVMLVILYS-RVGRSVTDVYLLNLALADLLFALTLPIWAAS--KVNGWIFGTF 108
Query: 86 GCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVAL 145
C + L +++ G+ LA +++DRYL +VH + G W L + L
Sbjct: 109 LCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGC-WGLSMNL 167
Query: 146 TCPGLLISEAAQ---NSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIR 202
+ P L +A +S C+ + ++ + F++P +++FC +R
Sbjct: 168 SLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLR 227
Query: 203 ALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLP---CFLARVLMHIFQNLGSCRALCA 259
L K + RA ++ VV++F LC+LP LA LM SC
Sbjct: 228 TLFKA-----HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNN 282
Query: 260 VAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRV 296
+ D T L +LHS LNP++Y F FR + ++
Sbjct: 283 IGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKI 319
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 105 bits (261), Expect = 7e-23
Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 7/278 (2%)
Query: 19 VLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQ 78
V+ G+ +G GNAV + T++F++R WK + +LNLA DLL LPFL +Y S +
Sbjct: 38 VIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGE 97
Query: 79 AWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLV 138
W G C + F + + FL ++ RY ++HP ++ + A+ +V
Sbjct: 98 NWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVV 157
Query: 139 WLLMVALTCP--GLLISEAAQNSTRCHSFYSRADGSFSIIWQE-ALSCLQFVLPFGLIVF 195
W++ + P L+ S N + C S +D +I W L+ F LP ++
Sbjct: 158 WIISLVAVIPMTFLITSTNRTNRSACLDLTS-SDELNTIKWYNLILTATTFCLPLVIVTL 216
Query: 196 CNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNLG-SC 254
C II L L+ Q+A+ L L+++ F +CFLP + RV+ + L SC
Sbjct: 217 CYTTIIHTLTHGLQTDSCLK--QKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISC 274
Query: 255 RALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSS 292
+ V+ L L++ N ++Y S F+ +
Sbjct: 275 SIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQA 312
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.141 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,043,951
Number of Sequences: 37866
Number of extensions: 489190
Number of successful extensions: 2863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 316
Number of HSP's successfully gapped in prelim test: 284
Number of HSP's that attempted gapping in prelim test: 1705
Number of HSP's gapped (non-prelim): 759
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.