Search of human proteins with 150456415

Search of human proteins with 150456415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150456415 HEAT repeat containing 5A [Homo sapiens]
         (1753 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150456415 HEAT repeat containing 5A [Homo sapiens]                3433   0.0  
gi|55749742 HEAT repeat containing 5B [Homo sapiens]                 1959   0.0  
gi|170763479 MMS19 nucleotide excision repair homolog [Homo sapi...    39   0.058
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]          37   0.13 
gi|73695475 protein BAP28 [Homo sapiens]                               35   0.84 
gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens]                33   1.9  
gi|119874201 furry-like [Homo sapiens]                                 32   4.2  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    31   9.3  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    31   9.3  

>gi|150456415 HEAT repeat containing 5A [Homo sapiens]
          Length = 1753

 Score = 3433 bits (8902), Expect = 0.0
 Identities = 1753/1753 (100%), Positives = 1753/1753 (100%)

Query: 1    MLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQID 60
            MLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQID
Sbjct: 1    MLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQID 60

Query: 61   AVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTD 120
            AVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTD
Sbjct: 61   AVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTD 120

Query: 121  VAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCL 180
            VAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCL
Sbjct: 121  VAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCL 180

Query: 181  HCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKI 240
            HCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKI
Sbjct: 181  HCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKI 240

Query: 241  IMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASP 300
            IMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASP
Sbjct: 241  IMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASP 300

Query: 301  KDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLT 360
            KDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLT
Sbjct: 301  KDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLT 360

Query: 361  QLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAA 420
            QLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAA
Sbjct: 361  QLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAA 420

Query: 421  STFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDS 480
            STFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDS
Sbjct: 421  STFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDS 480

Query: 481  VPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSS 540
            VPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSS
Sbjct: 481  VPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSS 540

Query: 541  VSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFT 600
            VSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFT
Sbjct: 541  VSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFT 600

Query: 601  AGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSP 660
            AGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSP
Sbjct: 601  AGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSP 660

Query: 661  DVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITT 720
            DVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITT
Sbjct: 661  DVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITT 720

Query: 721  LGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVS 780
            LGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVS
Sbjct: 721  LGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVS 780

Query: 781  CLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEG 840
            CLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEG
Sbjct: 781  CLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEG 840

Query: 841  ALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTM 900
            ALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTM
Sbjct: 841  ALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTM 900

Query: 901  QEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALA 960
            QEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALA
Sbjct: 901  QEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALA 960

Query: 961  QEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPG 1020
            QEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPG
Sbjct: 961  QEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPG 1020

Query: 1021 HVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSS 1080
            HVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSS
Sbjct: 1021 HVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSS 1080

Query: 1081 LTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIR 1140
            LTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIR
Sbjct: 1081 LTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIR 1140

Query: 1141 NGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENA 1200
            NGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENA
Sbjct: 1141 NGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENA 1200

Query: 1201 KLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPED 1260
            KLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPED
Sbjct: 1201 KLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPED 1260

Query: 1261 VYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELL 1320
            VYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELL
Sbjct: 1261 VYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELL 1320

Query: 1321 NVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGK 1380
            NVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGK
Sbjct: 1321 NVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGK 1380

Query: 1381 DTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLVSAAL 1440
            DTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLVSAAL
Sbjct: 1381 DTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLVSAAL 1440

Query: 1441 VILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSP 1500
            VILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSP
Sbjct: 1441 VILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSP 1500

Query: 1501 MARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIP 1560
            MARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIP
Sbjct: 1501 MARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIP 1560

Query: 1561 CLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEID 1620
            CLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEID
Sbjct: 1561 CLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEID 1620

Query: 1621 KRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLLDENSLGSATSIM 1680
            KRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLLDENSLGSATSIM
Sbjct: 1621 KRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLLDENSLGSATSIM 1680

Query: 1681 RNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSP 1740
            RNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSP
Sbjct: 1681 RNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSP 1740

Query: 1741 GKNSSIQLKTSFL 1753
            GKNSSIQLKTSFL
Sbjct: 1741 GKNSSIQLKTSFL 1753


>gi|55749742 HEAT repeat containing 5B [Homo sapiens]
          Length = 2071

 Score = 1959 bits (5076), Expect = 0.0
 Identities = 1017/1786 (56%), Positives = 1320/1786 (73%), Gaps = 41/1786 (2%)

Query: 1    MLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQID 60
            MLK   SV+R+VRVGVTQAYVVFV+TLGG WLE++FA F SH+L L S  HP+ATQT ++
Sbjct: 292  MLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVS--HPRATQTHVE 349

Query: 61   AVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTD 120
            AV  RRCVSFILR T+G LLGEKAQ+AA K+ICQAI K  K ++AV++D + E + G+ D
Sbjct: 350  AVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSGENKSGAAD 409

Query: 121  VAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCL 180
            +AASQH++VCALQELG+L+ +L  TA+PL+Q++S GLL+ + SV+LHPS++ RLAAAWCL
Sbjct: 410  IAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCL 469

Query: 181  HCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKI 240
             C+AVALP  LTP LDRC ERL   K+SPEAV+G+SFA+AALLG V  CPLGIPH KGK+
Sbjct: 470  RCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKM 529

Query: 241  IMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASP 300
            ++++AEDLL +AAQNSRLS QRTQAGWLL+ ALMTLGP+VV +HL ++LLLW+ VFP S 
Sbjct: 530  VVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSL 589

Query: 301  KDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLT 360
            K+LE EK+RGDSFTWQVTLEGRAGALCA++SFV+HC +LLTE+V ++L+ P+ CA+ +++
Sbjct: 590  KELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMS 649

Query: 361  QLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAA 420
             + S++K +G+ LK  + + R RLY++L LLPP+TYEG+  A+LREL A+ T  D     
Sbjct: 650  HIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANT 709

Query: 421  STFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDS 480
            +T LL  LCH DD ++L  +LQETDH+ IE+QL   +    G+LE+DP SIY +   G++
Sbjct: 710  TTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEA 769

Query: 481  VPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSS 540
            VP PLP  +SVI ++  LFGVV  HV    RL +L+   + +K  KG RQQ VQL++ ++
Sbjct: 770  VPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLNIFTA 829

Query: 541  VSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFT 600
            V S LK +A +K  LGPEE+++ ALTLVMG L++PNP+LRCAA E+  R+AQVV +  F 
Sbjct: 830  VLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFI 889

Query: 601  AGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSP 660
            A +AQ SFDKLKSARDVV+RTGHSLALG LHRY+GGI S QHL + + IL  LAQD TSP
Sbjct: 890  ARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSP 949

Query: 661  DVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITT 720
            +VQTW+LHSL+LI+DS+GP+Y  +VEPTLSL++ LLL VPP+H EVHQ LGRCL A+ITT
Sbjct: 950  EVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITT 1009

Query: 721  LGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVS 780
            +GPELQGN  + ST+R+SCL+GCA+ QD+ D LVQA AISCLQQLHMFAPRHVNLSSLV 
Sbjct: 1010 VGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVP 1069

Query: 781  CLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDA--------- 831
             LCV+LCS +LLLRRA +ACLRQL QREAAEV E+A+ LAK++ ++ +  A         
Sbjct: 1070 SLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGV 1129

Query: 832  -------------NIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWL 878
                         NI E GLEG L  +LD+ETD +LC DI +TL +ML+S+AVEKLS WL
Sbjct: 1130 SSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWL 1189

Query: 879  KLCKDVLAASADFTAVTCVDTMQEEEGDK----GDDASVLTTRRDEKSHPFTNPRWATRV 934
             LCKDVLAAS+D +  T + + ++EE +K     DD    T   ++KS PF  PRWATRV
Sbjct: 1190 MLCKDVLAASSDMSTATLLSSGKDEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRV 1249

Query: 935  FAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQ 994
            FAA+C+CRIIN CENA+ AHFD+ALA+  K R+  ND LVLHL+DLIRMAFMAATDHS+Q
Sbjct: 1250 FAADCLCRIINLCENADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQ 1309

Query: 995  LRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQV 1054
            LR++GL+ L  +I++FA+VPEPEFPGHVILEQYQANVGAALRPAF+ +TP D+ AKACQV
Sbjct: 1310 LRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQV 1369

Query: 1055 CSAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEV 1114
            CS WI SGVVSDLNDLRRVH LLVSSL K+QAGK + S LY ESA+TME LAVLKAWAEV
Sbjct: 1370 CSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEV 1429

Query: 1115 YIIAV----QRHKNHRQPLKTTTCLEDGIRN-GSCSSDGLLDLVYADLGTLSRLWLAALQ 1169
            Y++A+    +     ++ +K T   +D          D L+ LV  +L TLSRLWLAAL+
Sbjct: 1430 YVVAMNIKKEAESKPKRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALK 1489

Query: 1170 DFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADP 1229
            D+ALLTLP+EF+SQLP +GGAFYT ET + A+LHY NSWA ILHA ALWL STGF  ++ 
Sbjct: 1490 DYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSES 1549

Query: 1230 DEGA--SNLSRPVTPTSMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATME 1287
             E A  S L +  T  ++ Q S +  + KS  ++  DR HLILG+S++FLCS R +  +E
Sbjct: 1550 TEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIE 1609

Query: 1288 SITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQII 1347
             +TACL AL  LLD P+ R  I  DQ +G+ELL+VLHR++LT    S+QL    VV+QI+
Sbjct: 1610 HVTACLQALHTLLDSPYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIV 1669

Query: 1348 CAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQL 1407
             AAQ++++EKR +   DD   EKE     GEG D+GGL+PGKSLVFAT+EL + ILVR +
Sbjct: 1670 RAAQDYLQEKRNTLNEDD--MEKEACTVLGEGGDSGGLIPGKSLVFATMELLMFILVRHM 1727

Query: 1408 PELNPKLTGSPGVKATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTI 1467
            P L+ K++ SP   ATK + L E+ +RLV+A + ILS+LP++CSP G ++ILPTIL+L  
Sbjct: 1728 PHLSTKVSDSPSHIATKTR-LSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIA 1786

Query: 1468 GVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKS-RTAWTDLLRSALTTILDCW 1526
             +L++TA+K    Q+   V+A+LQ +K I++  MA+ E   +  WT L+RS L  IL+  
Sbjct: 1787 RILKDTAIKSADNQVPPPVSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYS 1846

Query: 1527 DPVDETHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTY 1586
             P D      DEVS+LTAI +F+ S S E+  +  LQ  C+++FK  L   DP VQ K Y
Sbjct: 1847 QPEDSVPTP-DEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNALNSCDPWVQAKCY 1905

Query: 1587 QLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTV 1646
            QLL S+FQ+ N A+S PYI+SLA  ++EKL+ +++ +P +  EL   QEGIKVLETLV +
Sbjct: 1906 QLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVAL 1965

Query: 1647 AEEHHRAQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLV 1706
             EE +R QL+A L+P LIS+LLDENS  SA+S  ++LH+FALQNLM IGP Y   FK+++
Sbjct: 1966 GEEQNRVQLLALLVPTLISYLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVM 2025

Query: 1707 ASSPALKARLEAAIKGNQESVKVKIPTSKYTKSPGKNSSIQLKTSF 1752
             ++P LK RLE A++ +Q S K K    +   +     +I+LKTSF
Sbjct: 2026 GAAPELKVRLETAVRASQAS-KAKAAARQPAPAIHSAPTIKLKTSF 2070


>gi|170763479 MMS19 nucleotide excision repair homolog [Homo
           sapiens]
          Length = 1030

 Score = 38.5 bits (88), Expect = 0.058
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 2/59 (3%)

Query: 750 PDCLVQAQAISCLQQLHMFAPRHVNL--SSLVSCLCVNLCSPYLLLRRAVLACLRQLVQ 806
           PDC+VQ   +SCLQ L + AP+ ++L   +LV+       SP + +R A L C+  L +
Sbjct: 925 PDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRIAALQCMHALTR 983


>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
          Length = 1236

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 54/299 (18%), Positives = 109/299 (36%), Gaps = 24/299 (8%)

Query: 671 SLIIDSAGPLYYVHVEPTLSLII-MLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNS 729
           +L +   GPL     E  +  I+  L  N+     ++    G  L  +++ L P   G+ 
Sbjct: 66  NLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSG 125

Query: 730 TSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQL--HMFAPRHVNLSSLVSCLCVNLC 787
            + +  R       + +    D  VQ +A+  L  +   +  P     +SL+ CL   L 
Sbjct: 126 LATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCLLPQLS 185

Query: 788 SPYLLLRRAVLACLRQLVQREAA----EVSEHAVMLAKDSREELTPDAN------IREVG 837
           SP L +R+  +  L  L    +     E+++H +      R   +P A       +  VG
Sbjct: 186 SPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVG 245

Query: 838 LEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCV 897
            +    +    +    L  D     +  L    ++    +L+ C   +          C+
Sbjct: 246 RQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCL 305

Query: 898 -----------DTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIIN 945
                      D+ ++EE  + +D+       +++     +  W  R  AA+C+  +I+
Sbjct: 306 QYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAALIS 364


>gi|73695475 protein BAP28 [Homo sapiens]
          Length = 2144

 Score = 34.7 bits (78), Expect = 0.84
 Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 32/190 (16%)

Query: 683  VHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQG--NSTSISTLRTSCL 740
            VH    + L I + L       +V Q    C  +++ T G  L    N +  + L+T  L
Sbjct: 843  VHFRVLMKLFIKVHLE------DVFQLFKFC--SVLWTYGSSLSNPLNCSVKTVLQTQAL 894

Query: 741  -LGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLA 799
             +GCA++         +Q   C  QL   +      S +V+ L +NL SP   +RRA + 
Sbjct: 895  YVGCAMLS--------SQKTQCKHQLASIS------SPVVTSLLINLGSPVKEVRRAAIQ 940

Query: 800  CLRQL--VQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHD 857
            CL+ L  V      + +H +  A    EE+T DA      L   L   L +E   +    
Sbjct: 941  CLQALSGVASPFYLIIDHLISKA----EEITSDAAYVIQDL-ATLFEELQREKKLKSHQK 995

Query: 858  IKETLNYMLT 867
            + ETL  +L+
Sbjct: 996  LSETLKNLLS 1005


>gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 2015

 Score = 33.5 bits (75), Expect = 1.9
 Identities = 44/210 (20%), Positives = 78/210 (37%), Gaps = 22/210 (10%)

Query: 1097 ESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCSSDGLLDLVYAD 1156
            E+AS +E  A L    EV  +    + NH   +  + CL   +      ++  L  +  +
Sbjct: 535  EAASVLEFPAFLSESLEVLCL----NDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPE 590

Query: 1157 LGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATA 1216
            LG L  LW    +D  +  +P+E   + P    ++  A+  +  K               
Sbjct: 591  LGQLGNLWQLDTEDLTISNVPAEIQKEGPKAMLSYLRAQLRKAEKCKLMKM--------- 641

Query: 1217 LWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPE-DVYTDRFHLILGISVE 1275
                    +V  P +G S L   +      Q     ATI++ + ++           SVE
Sbjct: 642  -------IIVGPPRQGKSTLLEILQTGRAPQVVHGEATIRTTKWELQRPAGSRAKVESVE 694

Query: 1276 F-LCSLRSDATMESITACLHALQALLDVPW 1304
            F +  +   A+M ++  C    +AL  V W
Sbjct: 695  FNVWDIGGPASMATVNQCFFTDKALYVVVW 724


>gi|119874201 furry-like [Homo sapiens]
          Length = 3013

 Score = 32.3 bits (72), Expect = 4.2
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 10/85 (11%)

Query: 1248 GSSSGATIKSP--EDVYTDRFHLILGISVEFLCSLRSDATMESITAC--LHALQALLDVP 1303
            G ++GA+   P     Y++ FH++ G ++  LCS R      +++    + AL ALL++P
Sbjct: 664  GVANGASHPPPLERSPYSNVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEIP 723

Query: 1304 WPRSKIGSDQDLGIELLNVLHRVIL 1328
                    D +L I++++ L   IL
Sbjct: 724  ------KGDDELAIDVMDRLSPSIL 742


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 31.2 bits (69), Expect = 9.3
 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 22/186 (11%)

Query: 1530 DETHQELDEVS-LLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDP---VVQIKT 1585
            DE  Q + E+S  +TA+   I+ + P++      Q+   D      E+K     V +IKT
Sbjct: 3858 DELTQSIQELSNQVTALQQKIMESLPQI------QRMADDVVAIESEVKSMEKRVSKIKT 3911

Query: 1586 YQLLHSIFQY-PNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLV 1644
              L   IF + P   + +  +      I+E ++ + K      AE+  +Q  +++ +T +
Sbjct: 3912 ILLSKEIFDFSPEEHLKHGEV------ILENIRPMKK----TIAEIVSYQVELRLPQTGM 3961

Query: 1645 TVAEEHHRAQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKS 1704
                   R   +   + +L +   ++N L        N  D  ++NL QI   YS+ F S
Sbjct: 3962 KPLPVFQRTNQLLQDIKLLENVTQEQNELLKVVIKQTNEWDEEIENLKQILNNYSAQF-S 4020

Query: 1705 LVASSP 1710
            L   SP
Sbjct: 4021 LEHMSP 4026


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 31.2 bits (69), Expect = 9.3
 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 22/186 (11%)

Query: 1530 DETHQELDEVS-LLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDP---VVQIKT 1585
            DE  Q + E+S  +TA+   I+ + P++      Q+   D      E+K     V +IKT
Sbjct: 3858 DELTQSIQELSNQVTALQQKIMESLPQI------QRMADDVVAIESEVKSMEKRVSKIKT 3911

Query: 1586 YQLLHSIFQY-PNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLV 1644
              L   IF + P   + +  +      I+E ++ + K      AE+  +Q  +++ +T +
Sbjct: 3912 ILLSKEIFDFSPEEHLKHGEV------ILENIRPMKK----TIAEIVSYQVELRLPQTGM 3961

Query: 1645 TVAEEHHRAQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKS 1704
                   R   +   + +L +   ++N L        N  D  ++NL QI   YS+ F S
Sbjct: 3962 KPLPVFQRTNQLLQDIKLLENVTQEQNELLKVVIKQTNEWDEEIENLKQILNNYSAQF-S 4020

Query: 1705 LVASSP 1710
            L   SP
Sbjct: 4021 LEHMSP 4026


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,804,842
Number of Sequences: 37866
Number of extensions: 2818936
Number of successful extensions: 6903
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 6860
Number of HSP's gapped (non-prelim): 34
length of query: 1753
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1637
effective length of database: 13,855,062
effective search space: 22680736494
effective search space used: 22680736494
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.