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Search of human proteins with 15042961
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15042961 HLA-B associated transcript 4 [Homo sapiens]
(356 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15042961 HLA-B associated transcript 4 [Homo sapiens] 733 0.0
gi|50962882 G patch domain containing 8 [Homo sapiens] 44 3e-04
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 43 4e-04
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 43 4e-04
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 43 4e-04
gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Ho... 42 6e-04
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 41 0.001
gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 40 0.002
gi|70995241 ankyrin repeat domain 10 [Homo sapiens] 40 0.002
gi|67906195 ankyrin repeat and sterile alpha motif domain contai... 40 0.003
gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens] 40 0.003
gi|163914396 TNNI3 interacting kinase isoform a [Homo sapiens] 40 0.003
gi|157504499 ankyrin repeat domain 47 [Homo sapiens] 40 0.003
gi|167900474 coiled-coil domain containing 75 [Homo sapiens] 40 0.004
gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens] 40 0.004
gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens] 40 0.004
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 39 0.005
gi|39725952 angiogenic factor VG5Q [Homo sapiens] 39 0.007
gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 37 0.021
gi|187608516 centaurin, beta 2 [Homo sapiens] 37 0.021
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 37 0.021
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 37 0.021
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 37 0.027
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 37 0.027
gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapi... 37 0.035
gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapi... 37 0.035
gi|95147559 ankyrin repeat domain 43 [Homo sapiens] 37 0.035
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 36 0.046
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 36 0.046
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 36 0.046
>gi|15042961 HLA-B associated transcript 4 [Homo sapiens]
Length = 356
Score = 733 bits (1892), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 1 MSRPLLITFTPATDPSDLWKDGQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRS 60
MSRPLLITFTPATDPSDLWKDGQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRS
Sbjct: 1 MSRPLLITFTPATDPSDLWKDGQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRS 60
Query: 61 QTEPARERKRKKRRIMKAPAAEAVAEGASGRHGQGRSLEAEDKMTHRILRAAQEGDLPEL 120
QTEPARERKRKKRRIMKAPAAEAVAEGASGRHGQGRSLEAEDKMTHRILRAAQEGDLPEL
Sbjct: 61 QTEPARERKRKKRRIMKAPAAEAVAEGASGRHGQGRSLEAEDKMTHRILRAAQEGDLPEL 120
Query: 121 RRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDA 180
RRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDA
Sbjct: 121 RRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDA 180
Query: 181 AQLAEEAGFPEVARMVRESHGETRSPENRSPTPSLQYCENCDTHFQDSNHRTSTAHLLSL 240
AQLAEEAGFPEVARMVRESHGETRSPENRSPTPSLQYCENCDTHFQDSNHRTSTAHLLSL
Sbjct: 181 AQLAEEAGFPEVARMVRESHGETRSPENRSPTPSLQYCENCDTHFQDSNHRTSTAHLLSL 240
Query: 241 SQGPQPPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLGYRS 300
SQGPQPPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLGYRS
Sbjct: 241 SQGPQPPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLGYRS 300
Query: 301 APQPRVTHFPAWDTRAVAGRERPPRVATLSWREERRREEKDRAWERDLRTYMNLEF 356
APQPRVTHFPAWDTRAVAGRERPPRVATLSWREERRREEKDRAWERDLRTYMNLEF
Sbjct: 301 APQPRVTHFPAWDTRAVAGRERPPRVATLSWREERRREEKDRAWERDLRTYMNLEF 356
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/49 (46%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
Query: 251 LGVPISSP--GFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLG 297
L PI S G +LL + GW+ G GLG +GR +PIP V+K D G+G
Sbjct: 34 LDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMG 82
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/132 (27%), Positives = 51/132 (38%), Gaps = 17/132 (12%)
Query: 72 KRRIMKAPAAEAVAEGASGRHGQ-----GRSLEAEDKMTHRILRAAQEGDLPELRRLLEP 126
KR ++ +E +A G + SLE E + RI+ + LP +
Sbjct: 910 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 969
Query: 127 HEAGGAGG------------NINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCE 174
H A AG N+NA D+ WTPL CAA +L+ GAA +
Sbjct: 970 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1029
Query: 175 LSGRDAAQLAEE 186
+ AA EE
Sbjct: 1030 SDMQTAADKCEE 1041
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/132 (27%), Positives = 51/132 (38%), Gaps = 17/132 (12%)
Query: 72 KRRIMKAPAAEAVAEGASGRHGQ-----GRSLEAEDKMTHRILRAAQEGDLPELRRLLEP 126
KR ++ +E +A G + SLE E + RI+ + LP +
Sbjct: 781 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840
Query: 127 HEAGGAGG------------NINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCE 174
H A AG N+NA D+ WTPL CAA +L+ GAA +
Sbjct: 841 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
Query: 175 LSGRDAAQLAEE 186
+ AA EE
Sbjct: 901 SDMQTAADKCEE 912
>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
Length = 1090
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/183 (24%), Positives = 61/183 (33%), Gaps = 25/183 (13%)
Query: 11 PATDPSDLWKDGQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRSQTEPAR---- 66
P+ +P +L E E + A E + + AP Q PA
Sbjct: 797 PSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPA 856
Query: 67 ----ERKRKKRRIMKAPAAEAVAEGASGRHGQ-----GRSLEAEDKMTHRILRAAQEGDL 117
KR +K P +E G R SLE E + RI+ ++
Sbjct: 857 SHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSK 916
Query: 118 PELRRLLEPHEAGGAGG------------NINARDAFWWTPLMCAARAGQGAAVSYLLGR 165
P + H A AG N+NA D+ WTPL CAA L+
Sbjct: 917 PNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVES 976
Query: 166 GAA 168
GAA
Sbjct: 977 GAA 979
>gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Homo
sapiens]
Length = 335
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 14/141 (9%)
Query: 86 EGASGRHGQGRSLE-------AEDKMTH----RILRAAQEGDLPELRRLLEPHEAGGAGG 134
+G +G GR+L+ + + H R+ AA GDL LR LL+
Sbjct: 8 DGRAGPGSAGRNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRSRIN 67
Query: 135 NINARDAFWW--TPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
+ W TPL AA AG G+ V +L+ +GA V + ++ G+ A +A G E
Sbjct: 68 EKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRKGAE-VDLVDVKGQTALYVAVVNGHLES 126
Query: 193 ARMVRESHGETRSPENRSPTP 213
+++ E+ + + TP
Sbjct: 127 TQILLEAGADPNGSRHHRSTP 147
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/120 (30%), Positives = 48/120 (40%), Gaps = 8/120 (6%)
Query: 94 QGRSLEAEDKMTHRILR-AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAAR 152
+G LE ED H L AA++G + L+ G G NIN D WT L AA
Sbjct: 567 RGADLEIEDAHGHTPLTLAARQGHTKVVNCLI------GCGANINHTDQDGWTALRSAAW 620
Query: 153 AGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSPT 212
G VS LL G V + R A + A G ++ + + E +N T
Sbjct: 621 GGHTEVVSALLYAGVK-VDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRT 679
Score = 37.0 bits (84), Expect = 0.027
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
Query: 79 PAAEAVAEGASGRHGQGRSLEAEDK--MTHRILRAAQEGDLPELRRLLEPHEAGGAGGNI 136
PA++ A S +G ++ DK MT +L AA EG + + LLE G ++
Sbjct: 722 PASKGHASVVSLLIDRGAEVDHCDKDGMTP-LLVAAYEGHVDVVDLLLE------GGADV 774
Query: 137 NARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMV 196
+ D TPL+ AA G + V+ LL GAA V + GR +A G EV R +
Sbjct: 775 DHTDNNGRTPLLAAASMGHASVVNTLLFWGAA-VDSIDSEGRTVLSIASAQGNVEVVRTL 833
Query: 197 RESHGETRSPENRSPTP 213
+ + ++ TP
Sbjct: 834 LDRGLDENHRDDAGWTP 850
Score = 29.6 bits (65), Expect = 4.3
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 95 GRSLEAEDKMTHRILR-AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARA 153
G ++++ D +L A+ +G++ +R LL+ G + N RD WTPL AA
Sbjct: 804 GAAVDSIDSEGRTVLSIASAQGNVEVVRTLLD------RGLDENHRDDAGWTPLHMAAFE 857
Query: 154 GQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRES 199
G L+ +GA + GR LA + G + +++ E+
Sbjct: 858 GHRLICEALIEQGAR-TNEIDNDGRIPFILASQEGHYDCVQILLEN 902
>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
Length = 1076
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 109 LRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAA 168
L AA D R+L H+A +NA D T LM AA GQ AAV +LL RG A
Sbjct: 862 LHAAAFADNVSGLRMLLQHQA-----EVNATDHTGRTALMTAAENGQTAAVEFLLYRGKA 916
Query: 169 WVGVCELSGRDAAQLAEEAGFPEVARMV 196
+ V + + A LA G + A M+
Sbjct: 917 DLTVLDENKNTALHLACSKGHEKCALMI 944
Score = 36.6 bits (83), Expect = 0.035
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 6/57 (10%)
Query: 111 AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
AA GD+P L+ LL +G N+NA+D W TPL AA + + LL A
Sbjct: 48 AAYVGDVPILQLLLM------SGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSA 98
Score = 34.7 bits (78), Expect = 0.13
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 6/102 (5%)
Query: 95 GRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAG 154
G ++ A+D + L A ++ LL H A ++NARD W TPL AA A
Sbjct: 64 GANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSA-----DVNARDKLWQTPLHVAA-AN 117
Query: 155 QGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMV 196
+ + L + + V + SGR A A +G E ++
Sbjct: 118 RATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLL 159
Score = 29.3 bits (64), Expect = 5.6
Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 8/121 (6%)
Query: 94 QGRSLEAEDKMTHRILR-AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAAR 152
+G SL DK + L AA G L L+ L+ G ++ +D + L AA
Sbjct: 162 KGASLNVCDKKERQPLHWAAFLGHLEVLKLLV------ARGADLGCKDRKGYGLLHTAAA 215
Query: 153 AGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSPT 212
+GQ V YLL GA + G A +A G VA + + P ++ T
Sbjct: 216 SGQIEVVKYLLRMGAE-IDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFT 274
Query: 213 P 213
P
Sbjct: 275 P 275
Score = 29.3 bits (64), Expect = 5.6
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 73 RRIMKAPAAEAVAEGASGRH--GQGRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAG 130
R+++ + ++ S H G + D + L AA G E LL
Sbjct: 389 RKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLL----- 443
Query: 131 GAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
+G ++ RD F TPL AA G L+ GA
Sbjct: 444 SSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGA 480
Score = 28.5 bits (62), Expect = 9.6
Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 4/89 (4%)
Query: 92 HGQGRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAA 151
HG ++ + + AA G L L++ +G + DA+ TPLM A
Sbjct: 640 HGASALIKERKRKWTPLHAAAASGHTDSLHLLID---SGERADITDVMDAYGQTPLMLAI 696
Query: 152 RAGQGAAVSYLLGRGAAWVGVCELSGRDA 180
G V LL +G+ +L GR A
Sbjct: 697 MNGHVDCVHLLLEKGST-ADAADLRGRTA 724
>gi|70995241 ankyrin repeat domain 10 [Homo sapiens]
Length = 420
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 132 AGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPE 191
AG NIN D TP+ AAR+G +S L+ G A V + SG AA +A+ GF E
Sbjct: 114 AGANINKPDCEGETPIHKAARSGSLECISALVANG-AHVDLRNASGLTAADIAQTQGFQE 172
Query: 192 VARMV 196
A+ +
Sbjct: 173 CAQFL 177
>gi|67906195 ankyrin repeat and sterile alpha motif domain
containing 6 [Homo sapiens]
Length = 871
Score = 40.0 bits (92), Expect = 0.003
Identities = 44/171 (25%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 36 DGAAARAFYEALIGDESSAPDSQRSQTEPARERKRKKRRIMKAPAAEAVAE------GAS 89
+G AF L + ++ R EP ++ +A A A AE A+
Sbjct: 3 EGGLPPAFQLLLRACDQGDTETARRLLEPGAAEPAERGAEPEAGAEPAGAEVAGPGAAAA 62
Query: 90 GRHGQGRSLEAEDKMTHRILR-AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLM 148
G G ++ D+ + L+ AA G P +R LL G ++N+R+ + W+ LM
Sbjct: 63 GAVGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLR------RGASVNSRNHYGWSALM 116
Query: 149 CAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRES 199
AAR G + LL GA V G +A G V +++ E+
Sbjct: 117 QAARFGHVSVAHLLLDHGAD-VNAQNRLGASVLTVASRGGHLGVVKLLLEA 166
Score = 28.5 bits (62), Expect = 9.6
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 7/61 (11%)
Query: 108 ILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFW-WTPLMCAARAGQGAAVSYLLGRG 166
++ AA G L ++ L+E H +++ +D+ WT LM A G V YLL +G
Sbjct: 330 LMLAAVTGQLALVQLLVERH------ADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQG 383
Query: 167 A 167
A
Sbjct: 384 A 384
>gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens]
Length = 835
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G N+N +DA ++TPL AA G LL GA V V G LA GF +
Sbjct: 157 GANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGAD-VNVSGEVGDRPLHLASAKGFLNI 215
Query: 193 ARMVRE--SHGETRSPENRSPTPSLQYCENCDTH 224
A+++ E S + + +N P L +C H
Sbjct: 216 AKLLMEEGSKADVNAQDNEDHVP-LHFCSRFGHH 248
>gi|163914396 TNNI3 interacting kinase isoform a [Homo sapiens]
Length = 936
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G N+N +DA ++TPL AA G LL GA V V G LA GF +
Sbjct: 258 GANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGAD-VNVSGEVGDRPLHLASAKGFLNI 316
Query: 193 ARMVRE--SHGETRSPENRSPTPSLQYCENCDTH 224
A+++ E S + + +N P L +C H
Sbjct: 317 AKLLMEEGSKADVNAQDNEDHVP-LHFCSRFGHH 349
>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
Length = 821
Score = 40.0 bits (92), Expect = 0.003
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G ++NA+DA T LMCA+ G+ V LL + + + G A +A EA EV
Sbjct: 719 GADVNAQDADGATALMCASEYGRLDTVRLLLTQPGCDPAILDNEGTSALAIALEAEQDEV 778
Query: 193 ARMVRESHGETRSPENRSPTP 213
A ++ +H + P+ +S +P
Sbjct: 779 AALL-HAHLSSGQPDTQSESP 798
Score = 30.4 bits (67), Expect = 2.5
Identities = 64/276 (23%), Positives = 96/276 (34%), Gaps = 35/276 (12%)
Query: 39 AARAFYEALIGDESSAPDSQRSQTEPARERKRKKRRIMKA-----PAAEAVAE--GASGR 91
AA A E + P+++ + E A E + +A AAE E AS
Sbjct: 304 AAEAVPETREAGAQAVPETREAGVEAAPETVEADAWVTEALLGLPAAAERELELLRASLE 363
Query: 92 HGQGRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAA 151
H +G S +LR G L EL E E AG R+A TP CA
Sbjct: 364 HQRGVS---------ELLR----GRLRELEEAREAAEEAAAGARAQLREATTQTPWSCAE 410
Query: 152 RAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSP 211
+A Q + + + D + AG + + + + T + S
Sbjct: 411 KAAQTESPA----EAPSLTQESSPGSMDGDRAVAPAG---ILKSIMKKRDGTPGAQPSSG 463
Query: 212 TPSLQYCENCDTHFQDSNHR-TSTAHLLSLSQGPQPPNLPLGVPISSPGFKLLLRGGWEP 270
SLQ+ + ++ S+ S + S + G +PP SS G GG +
Sbjct: 464 PKSLQFVGVLNGEYESSSSEDASDSDGDSENGGAEPPG-------SSSGSGDDSGGGSDS 516
Query: 271 GMGLGPRGEGRANPIPTVLKRDQEGLGYRSAPQPRV 306
G P G +P P Q+ R PR+
Sbjct: 517 GTPGPPSGGDIRDPEPEAEAEPQQVAQGRCELSPRL 552
>gi|167900474 coiled-coil domain containing 75 [Homo sapiens]
Length = 259
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/124 (21%), Positives = 53/124 (42%)
Query: 226 QDSNHRTSTAHLLSLSQGPQPPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPI 285
Q++N + L Q + L + + GF LL + G++ G LG G G PI
Sbjct: 40 QEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPI 99
Query: 286 PTVLKRDQEGLGYRSAPQPRVTHFPAWDTRAVAGRERPPRVATLSWREERRREEKDRAWE 345
P +K + G+G+ ++ + + + + + + A +R + ++ + E
Sbjct: 100 PLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLE 159
Query: 346 RDLR 349
DLR
Sbjct: 160 GDLR 163
>gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 6/60 (10%)
Query: 108 ILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
++ A G++ ++ LLE G N+NA D F WTPL A AGQ V L+ GA
Sbjct: 529 LMTACASGNIDVVKFLLEK------GANVNATDNFLWTPLHFACHAGQQDIVELLVESGA 582
Score = 36.2 bits (82), Expect = 0.046
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 98 LEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGA 157
++ +K+ I + GDL L++ E +G ++ +D ++ TPLM A +G
Sbjct: 486 IDDSEKVFSNINIITKAGDLASLKKAFE------SGIPVDMKDNYYKTPLMTACASGNID 539
Query: 158 AVSYLLGRGA--------AWVGV---CELSGRDAAQLAEEAGFPEVARMVRESHGETRSP 206
V +LL +GA W + C +D +L E+G A + S R+
Sbjct: 540 VVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAI 599
Query: 207 ENRSPTPSLQYCENCDTHFQDSNHRTSTA 235
E+ +++Y + FQ N + +A
Sbjct: 600 ES-CRLDTVKYLLDIGAKFQLENRKGHSA 627
>gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 6/60 (10%)
Query: 108 ILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
++ A G++ ++ LLE G N+NA D F WTPL A AGQ V L+ GA
Sbjct: 529 LMTACASGNIDVVKFLLEK------GANVNATDNFLWTPLHFACHAGQQDIVELLVESGA 582
Score = 36.2 bits (82), Expect = 0.046
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 98 LEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGA 157
++ +K+ I + GDL L++ E +G ++ +D ++ TPLM A +G
Sbjct: 486 IDDSEKVFSNINIITKAGDLASLKKAFE------SGIPVDMKDNYYKTPLMTACASGNID 539
Query: 158 AVSYLLGRGA--------AWVGV---CELSGRDAAQLAEEAGFPEVARMVRESHGETRSP 206
V +LL +GA W + C +D +L E+G A + S R+
Sbjct: 540 VVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAI 599
Query: 207 ENRSPTPSLQYCENCDTHFQDSNHRTSTA 235
E+ +++Y + FQ N + +A
Sbjct: 600 ES-CRLDTVKYLLDIGAKFQLENRKGHSA 627
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/105 (35%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 111 AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWV 170
AA +G L + L E H GA G +N WTPL AAR G+ A VS LL GA
Sbjct: 600 AAYKGHLEIIHLLAESHANMGALGAVN------WTPLHLAARHGEEAVVSALLQCGAD-P 652
Query: 171 GVCELSGRDAAQLA-EEAGFPEVARMVRESHGETRSPENRSPTPS 214
E SG LA + + F V ++ E H + TP+
Sbjct: 653 NAAEQSGWTPLHLAVQRSTFLSVINLL-EHHANVHARNKVGWTPA 696
>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
Length = 714
Score = 38.9 bits (89), Expect = 0.007
Identities = 20/52 (38%), Positives = 28/52 (53%)
Query: 246 PPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLG 297
P ++ + S+ G K+L + GW+ G GLG G G PI L+R GLG
Sbjct: 610 PASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLG 661
>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
Length = 399
Score = 37.4 bits (85), Expect = 0.021
Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 22/161 (13%)
Query: 56 DSQRSQTEPARERKRKKRRIMKAPAAEAVA---EGASGRHGQGRSLEAEDKMTHRILRAA 112
DSQR + E + ++ R M+ + EA+ EG S G G +L+A
Sbjct: 2 DSQRPEPRE-EEEEEQELRWMELDSEEALGTRTEGPSVVQGWGH-----------LLQAV 49
Query: 113 QEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGV 172
G + +LL G ++ RD TPL A G V LL RGA VG
Sbjct: 50 WRGPAGLVTQLLRQ------GASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAP-VGA 102
Query: 173 CELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSPTP 213
+ +GR A A G VA ++ + + TP
Sbjct: 103 VDRAGRTALHEAAWHGHSRVAELLLQRGASAAARSGTGLTP 143
Score = 35.0 bits (79), Expect = 0.10
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 13/102 (12%)
Query: 94 QGRSLEAEDKMTHRILR-AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAAR 152
QG ++A D + L A++EG + LL+ G ++A TPL AA
Sbjct: 291 QGAEVDARDTLGLTPLHHASREGHVEVAGCLLD------RGAQVDATGWLRKTPLHLAAE 344
Query: 153 AGQGAAVSYLLGRGAA------WVGVCELSGRDAAQLAEEAG 188
G G V LL RGA+ W V ++ D Q E G
Sbjct: 345 RGHGPTVGLLLSRGASPTLRTQWAEVAQMPEGDLPQALPELG 386
Score = 32.0 bits (71), Expect = 0.87
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 7/106 (6%)
Query: 108 ILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
+L AA G LR LL G ++ARD T L AA G+ + LLG GA
Sbjct: 207 LLVAAAAGRGAALRFLL------ARGARVDARDGAGATALGLAAALGRSQDIEVLLGHGA 260
Query: 168 AWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSPTP 213
G+ + GR A A G +++ E + + TP
Sbjct: 261 D-PGIRDRHGRSALHRAAARGHLLAVQLLVTQGAEVDARDTLGLTP 305
Score = 30.8 bits (68), Expect = 1.9
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 10/66 (15%)
Query: 123 LLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQ 182
+LE AGGAG + L+ AA AG+GAA+ +LL RGA V + +G A
Sbjct: 192 VLELLAAGGAGLD---------GALLVAAAAGRGAALRFLLARGAR-VDARDGAGATALG 241
Query: 183 LAEEAG 188
LA G
Sbjct: 242 LAAALG 247
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 110 RAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
RAA G L ++ L+ G ++ARD TPL A+R G LL RGA
Sbjct: 275 RAAARGHLLAVQLLVTQ------GAEVDARDTLGLTPLHHASREGHVEVAGCLLDRGA 326
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 37.4 bits (85), Expect = 0.021
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 12/176 (6%)
Query: 22 GQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRSQTEPARERKRKKRRIMKAPAA 81
G QQ + ES +A + YE + S+ P + R A
Sbjct: 564 GIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMA 623
Query: 82 EAVAEGASGRHGQGRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDA 141
EA+A GA +E+ +++A G L LL+ G N+N RD
Sbjct: 624 EALAHGADVNWAN-----SEENKATPLIQAVLGGSLVTCEFLLQN------GANVNQRDV 672
Query: 142 FWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVR 197
PL A G V L RGA E G+D +A EA ++ ++R
Sbjct: 673 QGRGPLHHATVLGHTGQVCLFLKRGANQHATDE-EGKDPLSIAVEAANADIVTLLR 727
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
16A [Homo sapiens]
Length = 528
Score = 37.4 bits (85), Expect = 0.021
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 35/140 (25%)
Query: 68 RKRKKRRIMKAPAAEAVAEGASGRHGQGRSLEAEDKMTHRIL--------RAAQEGDLPE 119
+KR+ +++ AE A+G G + R A + ++L AA DL E
Sbjct: 27 QKRRAQQVKMWAQAEKEAQGKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEE 86
Query: 120 LRRLLEP-------HEAG--------------------GAGGNINARDAFWWTPLMCAAR 152
+R+ L +E G AG NINA D+ WTPL AA
Sbjct: 87 VRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAAT 146
Query: 153 AGQGAAVSYLLGRGAAWVGV 172
G V L+ GA + V
Sbjct: 147 CGHLHLVELLIASGANLLAV 166
Score = 29.3 bits (64), Expect = 5.6
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 108 ILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGA 167
+L A E LL H A +++A+D W PL AA GQ V L+ GA
Sbjct: 235 LLHVAAANGFSEAAALLLEHRA-----SLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGA 289
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 37.4 bits (85), Expect = 0.021
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 145 TPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETR 204
TPLM A+ G A S LL RGA V V + + + A LA E G EVA ++ SHG
Sbjct: 155 TPLMIASLGGHAAICSQLLQRGAR-VNVTDKNDKSALILACEKGSAEVAELLL-SHGADA 212
Query: 205 SPENRSPTPSLQYCENCDTHFQD 227
+ + +L Y H QD
Sbjct: 213 GAVDSTGHDALHYA----LHTQD 231
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 37.0 bits (84), Expect = 0.027
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 135 NINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
N+N +D WTPL AA G Y + GA+ VG+ G + LAEE ++
Sbjct: 116 NVNQQDNEGWTPLHAAASCGYLNIAEYFINHGAS-VGIVNSEGEVPSDLAEEPAMKDL 172
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 37.0 bits (84), Expect = 0.027
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 135 NINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
N+N +D WTPL AA G Y + GA+ VG+ G + LAEE ++
Sbjct: 116 NVNQQDNEGWTPLHAAASCGYLNIAEYFINHGAS-VGIVNSEGEVPSDLAEEPAMKDL 172
>gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapiens]
Length = 1082
Score = 36.6 bits (83), Expect = 0.035
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 259 GFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLG 297
GF++L + GW+ G GLG G+G P+ + EGLG
Sbjct: 1015 GFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLG 1053
>gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapiens]
Length = 1082
Score = 36.6 bits (83), Expect = 0.035
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 259 GFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLG 297
GF++L + GW+ G GLG G+G P+ + EGLG
Sbjct: 1015 GFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLG 1053
>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
Length = 549
Score = 36.6 bits (83), Expect = 0.035
Identities = 28/72 (38%), Positives = 36/72 (50%)
Query: 111 AAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWV 170
AA+ GD +L+E GA ++NAR +TPL AA G A L+ R A V
Sbjct: 353 AAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQV 412
Query: 171 GVCELSGRDAAQ 182
V + SGR A Q
Sbjct: 413 HVRDHSGRRAYQ 424
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 36.2 bits (82), Expect = 0.046
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G NIN D W PL AA G +L+G+G A VG G +AEE E+
Sbjct: 9 GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQG-AHVGAVNSEGDTPLDIAEEEAMEEL 67
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 36.2 bits (82), Expect = 0.046
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G NIN D W PL AA G +L+G+G A VG G +AEE E+
Sbjct: 96 GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQG-AHVGAVNSEGDTPLDIAEEEAMEEL 154
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 36.2 bits (82), Expect = 0.046
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 133 GGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEV 192
G NIN D W PL AA G +L+G+G A VG G +AEE E+
Sbjct: 96 GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQG-AHVGAVNSEGDTPLDIAEEEAMEEL 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,795,680
Number of Sequences: 37866
Number of extensions: 935621
Number of successful extensions: 3726
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 3294
Number of HSP's gapped (non-prelim): 570
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.