BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|150170722 G protein-coupled receptor 50 [Homo sapiens] (617 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 1266 0.0 gi|5174593 melatonin receptor 1A [Homo sapiens] 347 2e-95 gi|5174595 melatonin receptor 1B [Homo sapiens] 331 1e-90 gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 124 2e-28 gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 124 3e-28 gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 124 3e-28 gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 124 3e-28 gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 124 3e-28 gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 124 3e-28 gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 124 3e-28 gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 124 3e-28 gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 124 3e-28 gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 124 3e-28 gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 124 3e-28 gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 121 2e-27 gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 121 2e-27 gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 121 2e-27 gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 121 2e-27 gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 120 5e-27 gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 117 3e-26 gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 116 5e-26 gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 115 1e-25 gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 112 8e-25 gi|167000885 galanin receptor 1 [Homo sapiens] 112 1e-24 gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens] 111 2e-24 gi|4557865 somatostatin receptor 5 [Homo sapiens] 109 7e-24 gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens] 109 9e-24 gi|223718087 opioid receptor, mu 1 isoform MOR1-K1 [Homo sapiens] 109 9e-24 gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 107 2e-23 gi|149944554 somatostatin receptor 4 [Homo sapiens] 107 2e-23 >gi|150170722 G protein-coupled receptor 50 [Homo sapiens] Length = 617 Score = 1266 bits (3276), Expect = 0.0 Identities = 617/617 (100%), Positives = 617/617 (100%) Query: 1 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR 60 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR Sbjct: 1 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR 60 Query: 61 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV 120 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV Sbjct: 61 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV 120 Query: 121 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF 180 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF Sbjct: 121 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF 180 Query: 181 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMF 240 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMF Sbjct: 181 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMF 240 Query: 241 VIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNEN 300 VIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNEN Sbjct: 241 VIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNEN 300 Query: 301 FRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEE 360 FRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEE Sbjct: 301 FRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEE 360 Query: 361 TPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP 420 TPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP Sbjct: 361 TPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP 420 Query: 421 VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGH 480 VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGH Sbjct: 421 VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGH 480 Query: 481 HVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELS 540 HVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELS Sbjct: 481 HVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELS 540 Query: 541 ASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDY 600 ASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDY Sbjct: 541 ASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDY 600 Query: 601 HDVVVIDVEDDPDEMAV 617 HDVVVIDVEDDPDEMAV Sbjct: 601 HDVVVIDVEDDPDEMAV 617 >gi|5174593 melatonin receptor 1A [Homo sapiens] Length = 350 Score = 347 bits (889), Expect = 2e-95 Identities = 157/307 (51%), Positives = 227/307 (73%), Gaps = 2/307 (0%) Query: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83 P L + C ++ TIVVD++GN +VIL+V +NKKLRN+GNIFVVSL+VAD++VAIYPYP Sbjct: 23 PSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYP 82 Query: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143 L+L ++ GW+L L CQ+ GF+ GLSV+GSIFNI IAINRYCYICHSL+Y++++S + Sbjct: 83 LVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSK 142 Query: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLI 203 N+ Y+++ W++T+ AVLPN+ GT++YDPR Y+C F + +T+ +V HF++P++I Sbjct: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMII 202 Query: 204 VGFCYVRIWTKVLAARD--PAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVA 261 V FCY+RIW VL R + P + + RNF+TMFV+F+LFA+CW P+N + + VA Sbjct: 203 VIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVA 262 Query: 262 VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSG 321 P M +IP WL++A+Y++AYFNSCLNA+IYGLLN+NFR+EY I ++ +FF Sbjct: 263 SDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVD 322 Query: 322 LISDIRE 328 +D+ + Sbjct: 323 SSNDVAD 329 >gi|5174595 melatonin receptor 1B [Homo sapiens] Length = 362 Score = 331 bits (849), Expect = 1e-90 Identities = 148/296 (50%), Positives = 223/296 (75%), Gaps = 6/296 (2%) Query: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83 PP + + +++T VD++GN +VIL+V +N+KLRN+GN+F+VSL++AD++VA YPYP Sbjct: 36 PPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYP 95 Query: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143 L+L A+ GW L + C+ F+ GLSV+GS+FNI AIAINRYCYICHS+ Y RI+ Sbjct: 96 LILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRW 155 Query: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLI 203 +T +++ + W++TV+A+LPN ++G++EYDPR Y+C F + +T +V IHF+LP+ + Sbjct: 156 HTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAV 215 Query: 204 VGFCYVRIWTKVLAARDPAGQNPDNQL----AEVRNFLTMFVIFLLFAVCWCPINVLTVL 259 V FCY+RIW VL AR A P+++L +++R+FLTMFV+F++FA+CW P+N + + Sbjct: 216 VSFCYLRIWVLVLQARRKA--KPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLA 273 Query: 260 VAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHP 315 VA++P+EMA +IP L++ +Y +AYFNSCLNA++YGLLN+NFRREY I A+ +P Sbjct: 274 VAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNP 329 >gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] Length = 430 Score = 124 bits (312), Expect = 2e-28 Identities = 78/304 (25%), Positives = 143/304 (47%), Gaps = 24/304 (7%) Query: 34 AMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGG 93 A + ++ ++GN++V V KN+ + N+F+++L+V+D+LV I+ P L I G Sbjct: 49 AYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITG 108 Query: 94 WDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITW 153 W C+M G + G+SV S+F +VAIA+ R+ I H + ++R + + + W Sbjct: 109 WPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVH--PFREKLTLRKALVTIAVIW 166 Query: 154 IMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFT--------------VTIVCIH-FV 198 + +L + P+ T+ + + + P+++ T++ H ++ Sbjct: 167 ALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYL 226 Query: 199 LPLLIVGFCYVRIWTKVLAARDPA-----GQNPDNQLAEVRNFLTMFVIFLLFAVCWCPI 253 PL ++ Y RI K+ A PA +P R + ++ L F + W P+ Sbjct: 227 APLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPL 286 Query: 254 NVLTVLVAVS--PKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHA 311 L +L+ + + + A+++A+FNS N +IYG NENFRR + F A Sbjct: 287 WALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRA 346 Query: 312 MRHP 315 P Sbjct: 347 RLCP 350 >gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] Length = 493 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 154 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 213 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 214 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 271 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 272 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 331 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 332 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 389 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 390 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 440 >gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] Length = 400 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] Length = 420 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] Length = 397 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] Length = 403 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] Length = 406 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] Length = 392 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] Length = 389 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] Length = 418 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] Length = 446 Score = 124 bits (311), Expect = 3e-28 Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 16/293 (5%) Query: 21 PEYPPALI--IFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV- 77 P P++I I + I VV L GN +V+ + + K++ + NI++ +L++AD L Sbjct: 61 PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT 120 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 + P+ + + M G W + C++V I ++ SIF + ++++RY +CH ++ Sbjct: 121 STLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 178 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLN-----NPVFTVTI 192 + RN I V WI++ LP M++ T +Y + C + + + + + Sbjct: 179 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 238 Query: 193 VCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLAEVRNFLTMFVIFLLFAVCWC 251 F++P+LI+ CY + ++ + R +G + D L + + V+ +F VCW Sbjct: 239 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRM--VLVVVAVFIVCWT 296 Query: 252 PINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 PI++ ++ A V+ E + +W + A + Y NSCLN V+Y L+ENF+R Sbjct: 297 PIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFKR 347 >gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] Length = 420 Score = 121 bits (304), Expect = 2e-27 Identities = 81/317 (25%), Positives = 154/317 (48%), Gaps = 32/317 (10%) Query: 18 LPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV 77 L QP+ II F + ++GN++V V +NK + N+F+++L+++D+LV Sbjct: 39 LHQPQVAAIFIISYFLIFFLC----MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLV 94 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 I+ P+ L I GW C++ G + G+SV S+F +VAIA++R + C ++ Sbjct: 95 GIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDR--FQCVVYPFK 152 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYD-------------PRTYTCIFNYLN 184 +++ + ++I W++ + + P+ + ++ + Y C ++ N Sbjct: 153 PKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPN 212 Query: 185 ---NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDP-AGQNPDNQLAEV-----RN 235 ++T + ++ PL ++ Y RI + A P G+ Q V + Sbjct: 213 QEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKI 272 Query: 236 FLTMFVIFLLFAVCWCPINVLTVL---VAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAV 292 + ++ LLF + W P+ L +L +SP E+ I ++Y A+++A+ NS +N + Sbjct: 273 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQ-IINIYIYPFAHWLAFGNSSVNPI 331 Query: 293 IYGLLNENFRREYWTIF 309 IYG NENFRR + F Sbjct: 332 IYGFFNENFRRGFQEAF 348 >gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] Length = 522 Score = 121 bits (304), Expect = 2e-27 Identities = 81/317 (25%), Positives = 154/317 (48%), Gaps = 32/317 (10%) Query: 18 LPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV 77 L QP+ II F + ++GN++V V +NK + N+F+++L+++D+LV Sbjct: 141 LHQPQVAAIFIISYFLIFFLC----MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLV 196 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 I+ P+ L I GW C++ G + G+SV S+F +VAIA++R + C ++ Sbjct: 197 GIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDR--FQCVVYPFK 254 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYD-------------PRTYTCIFNYLN 184 +++ + ++I W++ + + P+ + ++ + Y C ++ N Sbjct: 255 PKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPN 314 Query: 185 ---NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDP-AGQNPDNQLAEV-----RN 235 ++T + ++ PL ++ Y RI + A P G+ Q V + Sbjct: 315 QEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKI 374 Query: 236 FLTMFVIFLLFAVCWCPINVLTVL---VAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAV 292 + ++ LLF + W P+ L +L +SP E+ I ++Y A+++A+ NS +N + Sbjct: 375 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQ-IINIYIYPFAHWLAFGNSSVNPI 433 Query: 293 IYGLLNENFRREYWTIF 309 IYG NENFRR + F Sbjct: 434 IYGFFNENFRRGFQEAF 450 >gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] Length = 423 Score = 121 bits (304), Expect = 2e-27 Identities = 81/317 (25%), Positives = 154/317 (48%), Gaps = 32/317 (10%) Query: 18 LPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLV 77 L QP+ II F + ++GN++V V +NK + N+F+++L+++D+LV Sbjct: 42 LHQPQVAAIFIISYFLIFFLC----MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLV 97 Query: 78 AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYE 137 I+ P+ L I GW C++ G + G+SV S+F +VAIA++R + C ++ Sbjct: 98 GIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDR--FQCVVYPFK 155 Query: 138 RIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYD-------------PRTYTCIFNYLN 184 +++ + ++I W++ + + P+ + ++ + Y C ++ N Sbjct: 156 PKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPN 215 Query: 185 ---NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDP-AGQNPDNQLAEV-----RN 235 ++T + ++ PL ++ Y RI + A P G+ Q V + Sbjct: 216 QEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKI 275 Query: 236 FLTMFVIFLLFAVCWCPINVLTVL---VAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAV 292 + ++ LLF + W P+ L +L +SP E+ I ++Y A+++A+ NS +N + Sbjct: 276 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQ-IINIYIYPFAHWLAFGNSSVNPI 334 Query: 293 IYGLLNENFRREYWTIF 309 IYG NENFRR + F Sbjct: 335 IYGFFNENFRRGFQEAF 351 >gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] Length = 407 Score = 121 bits (304), Expect = 2e-27 Identities = 73/289 (25%), Positives = 138/289 (47%), Gaps = 13/289 (4%) Query: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83 P I+ A + +V ++GN +V+ + +K++R N F+V+L+ A+ +A + Sbjct: 28 PAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTV 87 Query: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143 + W C+ F +V SI+++ A+A +RY I H LQ S Sbjct: 88 VNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPR--LSAT 145 Query: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNP------VFTVTIVCIHF 197 T + + + W++ +L P Y T E P C+ + +P V+ + + + + Sbjct: 146 ATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205 Query: 198 VLPLLIVGFCYVRIWTKVLAARDPAGQNPDN---QLAEVRNFLTMFVIFLL-FAVCWCPI 253 LPLL++G+ Y + + A+ P G + D Q++ R + M ++ + FA+CW P Sbjct: 206 FLPLLVIGYAYTVVGITLWASEIP-GDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPF 264 Query: 254 NVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFR 302 ++ +L ++P K +YLA ++A ++ N +IY LN+ FR Sbjct: 265 HIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFR 313 >gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] Length = 384 Score = 120 bits (300), Expect = 5e-27 Identities = 75/303 (24%), Positives = 149/303 (49%), Gaps = 18/303 (5%) Query: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83 P A+I + A I++ + GN +I+ + K K++RN NI +V+LS +D+LVAI P Sbjct: 36 PLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLP 95 Query: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143 + W + C++ F+ +S+ SIF++V IA+ R+ I + + + R Sbjct: 96 FTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRP--NNR 153 Query: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDP----------RTYTCIFNYLNNP---VFTV 190 + + + + W++ V + LP + + +P Y C + ++ +T Sbjct: 154 HAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTT 213 Query: 191 TIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQL--AEVRNFLTMFV-IFLLFA 247 ++ + + PL + CY +I+ ++ + + DN+ +E + M + I + FA Sbjct: 214 LLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFA 273 Query: 248 VCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWT 307 VCW P+ + + + + +A N L+L + A ++C+N + YG LN+NF+R+ Sbjct: 274 VCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQF 333 Query: 308 IFH 310 F+ Sbjct: 334 FFN 336 >gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] Length = 311 Score = 117 bits (293), Expect = 3e-26 Identities = 71/286 (24%), Positives = 136/286 (47%), Gaps = 13/286 (4%) Query: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83 P I+ A + +V ++GN +V+ + +K++R N F+V+L+ A+ +A + Sbjct: 28 PAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTV 87 Query: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143 + W C+ F +V SI+++ A+A +RY I H LQ S Sbjct: 88 VNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPR--LSAT 145 Query: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNP------VFTVTIVCIHF 197 T + + + W++ +L P Y T E P C+ + +P V+ + + + + Sbjct: 146 ATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205 Query: 198 VLPLLIVGFCYVRIWTKVLAARDPAGQNPDN---QLAEVRNFLTMFVIFLL-FAVCWCPI 253 LPLL++G+ Y + + A+ P G + D Q++ R + M ++ + FA+CW P Sbjct: 206 FLPLLVIGYAYTVVGITLWASEIP-GDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPF 264 Query: 254 NVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNE 299 ++ +L ++P K +YLA ++A ++ N +IY LN+ Sbjct: 265 HIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310 >gi|157738685 G protein-coupled receptor 103 [Homo sapiens] Length = 431 Score = 116 bits (291), Expect = 5e-26 Identities = 78/304 (25%), Positives = 142/304 (46%), Gaps = 21/304 (6%) Query: 21 PEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIY 80 PE P + + V+ + L GN++V VT++K +R NIF+ SL+++D+L+ + Sbjct: 38 PELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFF 97 Query: 81 PYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIF 140 P+ + W C+MV F+ +VV I + IA+ R+ + H + + + Sbjct: 98 CIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQY 157 Query: 141 SVRNTCIYLVITWIMTVLAVLPNMYIGTIE--YD---PRTYTCIFNYLNNPV----FTVT 191 + R L + W++ V+ P ++ +E YD + + C +PV +T Sbjct: 158 TNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTF 217 Query: 192 IVCIHFVLPLLIVGFCYVRI----WTKVLAA-----RDPAGQNPDNQLAEVRNFLTMFV- 241 I+ I F+LPL+++ Y +I W K R G+ + + + M V Sbjct: 218 ILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVT 277 Query: 242 IFLLFAVCWCPINVLTVLVAVS--PKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNE 299 + LFAVCW P +V+ +++ S KE ++ I + NS N ++Y +NE Sbjct: 278 VVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNE 337 Query: 300 NFRR 303 NF++ Sbjct: 338 NFKK 341 >gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] Length = 381 Score = 115 bits (288), Expect = 1e-25 Identities = 75/295 (25%), Positives = 143/295 (48%), Gaps = 18/295 (6%) Query: 27 LIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLML 86 ++I +C++++ + +IGNS+VI V K K +R N F+ +L+VAD+LV P L Sbjct: 52 VLILAYCSIIL---LGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL 108 Query: 87 HAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRY-CYICHSLQYERIFSVRNT 145 +G W + + C +V + GL+V S + IA++R+ C + H E S R + Sbjct: 109 TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYH---LESKISKRIS 165 Query: 146 CIYLVITW-----IMTVLAVLPNMYIGTIEYDPRTYTCIFNY------LNNPVFTVTIVC 194 + + + W + + LA+ + I D C + + V++++ + Sbjct: 166 FLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLL 225 Query: 195 IHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPIN 254 I +VLPL I+ F Y RIW+K+ P N + + + ++FAV W P++ Sbjct: 226 ILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLH 285 Query: 255 VLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIF 309 + V + + + K ++ + IA ++ N ++YG +N N+R+ + + F Sbjct: 286 AFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAF 340 >gi|4758474 G protein-coupled receptor 10 [Homo sapiens] Length = 370 Score = 112 bits (281), Expect = 8e-25 Identities = 72/289 (24%), Positives = 146/289 (50%), Gaps = 16/289 (5%) Query: 27 LIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLML 86 LI+ ++ + +VV L+GN +++L + + ++L N N + +L+++D+L+ PL L Sbjct: 62 LIVLLYS---VVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTL 118 Query: 87 -HAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNT 145 +A GW C +V F+ ++V S+F + IA++RY + H L+ R S+R + Sbjct: 119 AYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR--RRISLRLS 176 Query: 146 CIYLVITWIMTVLAVLPN-MYIGTIEYDPRTYTCIFNYLNNP-----VFTVTIVCIHFVL 199 ++ W ++ + LP ++ +E P + + ++ ++ + ++L Sbjct: 177 AYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLL 236 Query: 200 PLLIVGFCYVRIWTKVLAARDPA----GQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINV 255 PLL++ YVR+ K+ P Q ++ R F + V+ ++FAVCW P++V Sbjct: 237 PLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHV 296 Query: 256 LTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRRE 304 +L + P + + L +++A ++C N IY L+++FR E Sbjct: 297 FNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREE 345 >gi|167000885 galanin receptor 1 [Homo sapiens] Length = 349 Score = 112 bits (280), Expect = 1e-24 Identities = 75/306 (24%), Positives = 151/306 (49%), Gaps = 21/306 (6%) Query: 19 PQPEYPPALIIFM--FCAMVI---TIVVDLIGNSMVILAVTKNK--KLRNSGNIFVVSLS 71 P PE P I + F +V+ + ++GNS+VI + ++K K R++ N+F+++LS Sbjct: 19 PAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLS 78 Query: 72 VADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYIC 131 +AD+ ++ P ++ W L C+ + + +S++ SIF + A++++RY I Sbjct: 79 IADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIV 138 Query: 132 HSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNP----- 186 HS + + RN + + W +++ P Y + + PR F + P Sbjct: 139 HSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGL-FHPRASNQTFCWEQWPDPRHK 197 Query: 187 -VFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLL 245 + V ++LPLL++ FCY ++ + + + ++ ++ + T+ V+ ++ Sbjct: 198 KAYVVCTFVFGYLLPLLLICFCYAKVLNHL--HKKLKNMSKKSEASKKKTAQTVLVVVVV 255 Query: 246 FAVCWCPINVLTVLV--AVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 F + W P +++ + V P A + + A+ +AY NS +N +IY L+ENFR+ Sbjct: 256 FGISWLPHHIIHLWAEFGVFPLTPASFL---FRITAHCLAYSNSSVNPIIYAFLSENFRK 312 Query: 304 EYWTIF 309 Y +F Sbjct: 313 AYKQVF 318 >gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens] Length = 319 Score = 111 bits (277), Expect = 2e-24 Identities = 68/254 (26%), Positives = 131/254 (51%), Gaps = 14/254 (5%) Query: 58 KLRNSGNIFVVSLSVADMLV-AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSI 116 K++ + NI++ +L++AD L + P+ + + M G W + C++V I ++ SI Sbjct: 19 KMKTATNIYIFNLALADALATSTLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSI 76 Query: 117 FNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTY 176 F + ++++RY +CH ++ + RN I V WI++ LP M++ T +Y + Sbjct: 77 FTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSI 136 Query: 177 TCIFNYLN-----NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQL 230 C + + + + + F++P+LI+ CY + ++ + R +G + D L Sbjct: 137 DCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNL 196 Query: 231 AEVRNFLTMFVIFLLFAVCWCPINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCL 289 + + V+ +F VCW PI++ ++ A V+ E + +W + A + Y NSCL Sbjct: 197 RRITRM--VLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCL 252 Query: 290 NAVIYGLLNENFRR 303 N V+Y L+ENF+R Sbjct: 253 NPVLYAFLDENFKR 266 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 109 bits (273), Expect = 7e-24 Identities = 75/278 (26%), Positives = 136/278 (48%), Gaps = 18/278 (6%) Query: 36 VITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWD 95 ++ L GN++VI V + K++ NI++++L+VAD+L + P + + W Sbjct: 48 LLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYML-GLPFLATQNAASFWP 106 Query: 96 LSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIM 155 + C++V + G++ S+F + ++++RY + H L R R + W++ Sbjct: 107 FGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVL 166 Query: 156 TVLAVLPNMYIGTIEYDPRTYTCIFNY-----LNNPVFTVTIVCIHFVLPLLIVGFCYVR 210 ++ LP + ++ TC ++ L VF + + F PLL++ CY+ Sbjct: 167 SLCMSLPLLVFADVQEGG---TCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLL 223 Query: 211 IWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCP---INVLTVLVAVSPKEM 267 I KV AA G +V + V+ L+FA CW P +N++ + VA+ P+E Sbjct: 224 IVVKVRAAGVRVGCVRRRSERKVTRMV--LVVVLVFAGCWLPFFTVNIVNLAVAL-PQEP 280 Query: 268 AGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREY 305 A LY ++Y NSC N V+YG L++NFR+ + Sbjct: 281 ASA---GLYFFVVILSYANSCANPVLYGFLSDNFRQSF 315 >gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens] Length = 300 Score = 109 bits (272), Expect = 9e-24 Identities = 67/253 (26%), Positives = 130/253 (51%), Gaps = 14/253 (5%) Query: 59 LRNSGNIFVVSLSVADMLV-AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIF 117 ++ + NI++ +L++AD L + P+ + + M G W + C++V I ++ SIF Sbjct: 1 MKTATNIYIFNLALADALATSTLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIF 58 Query: 118 NIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYT 177 + ++++RY +CH ++ + RN I V WI++ LP M++ T +Y + Sbjct: 59 TLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSID 118 Query: 178 CIFNYLN-----NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLA 231 C + + + + + F++P+LI+ CY + ++ + R +G + D L Sbjct: 119 CTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLR 178 Query: 232 EVRNFLTMFVIFLLFAVCWCPINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLN 290 + + V+ +F VCW PI++ ++ A V+ E + +W + A + Y NSCLN Sbjct: 179 RITRM--VLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLN 234 Query: 291 AVIYGLLNENFRR 303 V+Y L+ENF+R Sbjct: 235 PVLYAFLDENFKR 247 >gi|223718087 opioid receptor, mu 1 isoform MOR1-K1 [Homo sapiens] Length = 300 Score = 109 bits (272), Expect = 9e-24 Identities = 67/253 (26%), Positives = 130/253 (51%), Gaps = 14/253 (5%) Query: 59 LRNSGNIFVVSLSVADMLV-AIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIF 117 ++ + NI++ +L++AD L + P+ + + M G W + C++V I ++ SIF Sbjct: 1 MKTATNIYIFNLALADALATSTLPFQSVNYLM--GTWPFGTILCKIVISIDYYNMFTSIF 58 Query: 118 NIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYT 177 + ++++RY +CH ++ + RN I V WI++ LP M++ T +Y + Sbjct: 59 TLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSID 118 Query: 178 CIFNYLN-----NPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAG-QNPDNQLA 231 C + + + + + F++P+LI+ CY + ++ + R +G + D L Sbjct: 119 CTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLR 178 Query: 232 EVRNFLTMFVIFLLFAVCWCPINVLTVLVA-VSPKEMAGKIPNWLYLAAYFIAYFNSCLN 290 + + V+ +F VCW PI++ ++ A V+ E + +W + A + Y NSCLN Sbjct: 179 RITRM--VLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIA--LGYTNSCLN 234 Query: 291 AVIYGLLNENFRR 303 V+Y L+ENF+R Sbjct: 235 PVLYAFLDENFKR 247 >gi|223633971 G protein-coupled receptor 83 [Homo sapiens] Length = 423 Score = 107 bits (268), Expect = 2e-23 Identities = 77/310 (24%), Positives = 136/310 (43%), Gaps = 30/310 (9%) Query: 25 PALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPL 84 P + + A IV L GN +V + KN+++ ++ ++F+V+L+VAD+++ + P Sbjct: 68 PTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPF 127 Query: 85 MLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRN 144 L W + C + F S+ S + AIA++R+ I H L+ S+ Sbjct: 128 TLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPR--ISITK 185 Query: 145 TCIYLVITWIMTVLAVLPN---MYIGTIEYD------------PRTYTCIFNYLNNPVFT 189 IY+ + W M LP+ + T +Y P + YL+ F Sbjct: 186 GVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFI 245 Query: 190 VTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLA----EVRNFLTMFVIFLL 245 + ++LPLLI+ Y R+ K+ + A + + + ++ +L Sbjct: 246 LL-----YILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVL 300 Query: 246 FAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREY 305 FA+CW P+N +L++ + N LY A ++ A ++C N IY LNENFR E Sbjct: 301 FALCWFPLNCYVLLLS----SKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIEL 356 Query: 306 WTIFHAMRHP 315 + + P Sbjct: 357 KALLSMCQRP 366 >gi|149944554 somatostatin receptor 4 [Homo sapiens] Length = 388 Score = 107 bits (268), Expect = 2e-23 Identities = 69/279 (24%), Positives = 137/279 (49%), Gaps = 18/279 (6%) Query: 33 CAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIG 92 C + +V L+GN++VI + + K++ + NI++++L+VAD L + P + + ++ Sbjct: 52 CIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFML-SVPFVASSAALR 110 Query: 93 GWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVI- 151 W + C+ V + GL++ S+F + ++++RY + H L R + R + +I Sbjct: 111 HWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPL---RAATYRRPSVAKLIN 167 Query: 152 --TWIMTVLAVLPNMYIGTIE--YDPRTYTCIFNYLN---NPVFTVTIVCIHFVLPLLIV 204 W+ ++L LP + C + + + VF V + F+LP+L + Sbjct: 168 LGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAI 227 Query: 205 GFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSP 264 G CY+ I K+ A AG + +E + + ++ ++F +CW P V+ +L Sbjct: 228 GLCYLLIVGKMRAVALRAGWQ-QRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLL----- 281 Query: 265 KEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRR 303 + + + ++Y NSC N ++YG L++NFRR Sbjct: 282 NLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRR 320 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.134 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,801,809 Number of Sequences: 37866 Number of extensions: 1296380 Number of successful extensions: 10059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 510 Number of HSP's successfully gapped in prelim test: 595 Number of HSP's that attempted gapping in prelim test: 6450 Number of HSP's gapped (non-prelim): 2422 length of query: 617 length of database: 18,247,518 effective HSP length: 108 effective length of query: 509 effective length of database: 14,157,990 effective search space: 7206416910 effective search space used: 7206416910 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.