Search of human proteins with 150010558

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
         (1946 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             3770   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     2409   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  2401   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  2336   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  2318   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  2318   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  2315   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  2311   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  2310   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  2308   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  2300   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  1255   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  1241   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  1241   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  1239   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  1239   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   1236   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         1155   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         1152   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         1141   0.0  
gi|153945715 myosin VC [Homo sapiens]                                 590   e-168
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       564   e-160
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       558   e-158
gi|122937345 myosin VB [Homo sapiens]                                 551   e-156
gi|28416946 myosin 18A isoform a [Homo sapiens]                       496   e-140
gi|42794779 myosin 18A isoform b [Homo sapiens]                       494   e-139
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     489   e-138
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     489   e-138
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     489   e-138
gi|122937512 myosin VIIB [Homo sapiens]                               476   e-134

>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 3770 bits (9777), Expect = 0.0
 Identities = 1946/1946 (100%), Positives = 1946/1946 (100%)

Query: 1    MVESCLLTFRAFFWWIALIKMDLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGE 60
            MVESCLLTFRAFFWWIALIKMDLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGE
Sbjct: 1    MVESCLLTFRAFFWWIALIKMDLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGE 60

Query: 61   NAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVL 120
            NAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVL
Sbjct: 61   NAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVL 120

Query: 121  HTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAF 180
            HTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAF
Sbjct: 121  HTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAF 180

Query: 181  QDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTIL 240
            QDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTIL
Sbjct: 181  QDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTIL 240

Query: 241  EAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFY 300
            EAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFY
Sbjct: 241  EAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFY 300

Query: 301  QILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYG 360
            QILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYG
Sbjct: 301  QILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYG 360

Query: 361  CYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGN 420
            CYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGN
Sbjct: 361  CYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGN 420

Query: 421  EYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEIL 480
            EYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEIL
Sbjct: 421  EYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEIL 480

Query: 481  EYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPM 540
            EYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPM
Sbjct: 481  EYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPM 540

Query: 541  GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPY 600
            GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPY
Sbjct: 541  GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPY 600

Query: 601  NISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVA 660
            NISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVA
Sbjct: 601  NISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVA 660

Query: 661  SLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREG 720
            SLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREG
Sbjct: 661  SLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREG 720

Query: 721  FPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAG 780
            FPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAG
Sbjct: 721  FPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAG 780

Query: 781  FLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
            FLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP
Sbjct: 781  FLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840

Query: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
            WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI
Sbjct: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900

Query: 901  LQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECF 960
            LQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECF
Sbjct: 901  LQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECF 960

Query: 961  ELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLD 1020
            ELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLD
Sbjct: 961  ELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLD 1020

Query: 1021 DLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMEN 1080
            DLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMEN
Sbjct: 1021 DLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMEN 1080

Query: 1081 LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTT 1140
            LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTT
Sbjct: 1081 LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTT 1140

Query: 1141 RAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETT 1200
            RAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETT
Sbjct: 1141 RAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETT 1200

Query: 1201 SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKL 1260
            SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKL
Sbjct: 1201 SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKL 1260

Query: 1261 CTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNF 1320
            CTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNF
Sbjct: 1261 CTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNF 1320

Query: 1321 TRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEM 1380
            TRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEM
Sbjct: 1321 TRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEM 1380

Query: 1381 VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDA 1440
            VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDA
Sbjct: 1381 VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDA 1440

Query: 1441 LSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTY 1500
            LSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTY
Sbjct: 1441 LSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTY 1500

Query: 1501 EESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETE 1560
            EESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETE
Sbjct: 1501 EESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETE 1560

Query: 1561 GALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSR 1620
            GALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSR
Sbjct: 1561 GALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSR 1620

Query: 1621 IEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLK 1680
            IEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLK
Sbjct: 1621 IEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLK 1680

Query: 1681 EQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKK 1740
            EQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKK
Sbjct: 1681 EQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKK 1740

Query: 1741 KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQ 1800
            KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQ
Sbjct: 1741 KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQ 1800

Query: 1801 TITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK 1860
            TITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK
Sbjct: 1801 TITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK 1860

Query: 1861 ELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKE 1920
            ELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKE
Sbjct: 1861 ELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKE 1920

Query: 1921 RAEVAESQVNKLKIKAREFGKKVQEE 1946
            RAEVAESQVNKLKIKAREFGKKVQEE
Sbjct: 1921 RAEVAESQVNKLKIKAREFGKKVQEE 1946


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 2409 bits (6242), Expect = 0.0
 Identities = 1206/1929 (62%), Positives = 1562/1929 (80%), Gaps = 11/1929 (0%)

Query: 23   LSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVETA 82
            ++D G AA +LR+SE E L  Q    D + +C++PD +  +++A++  S + G VI ET 
Sbjct: 6    MADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKIL-SREGGKVIAETE 64

Query: 83   DGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVT 142
            +G+++++KED++ Q NPP+F+ IEDMAMLT L+E +VL  LK RY  WMIYTYSGLFCVT
Sbjct: 65   NGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVT 124

Query: 143  INPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGK 202
            +NPYKWLPVY  EV+AAY+GK+RSEAPPHIF++++NA+Q ML +RENQSIL TGESGAGK
Sbjct: 125  VNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGK 184

Query: 203  TVNSKHIIQYFATIAAMIESRKK------QGALEDQIMQANTILEAFGNAKTLRNDNSSR 256
            TVN+K +IQYFA+IAA+ +  KK      +G LEDQI+QAN  LEAFGNAKT+RNDNSSR
Sbjct: 185  TVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSR 244

Query: 257  FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
            FGKFIR+HFGA G L+S DI+ YLLEKSRVIFQ   ERNYHIFYQILS +K EL D+LLV
Sbjct: 245  FGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLV 304

Query: 316  SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
            + NP D+ F S G V+V S+DD+EEL+AT+ A D+LGF  +EK G YKLTGAIMH+GNMK
Sbjct: 305  TNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMK 364

Query: 376  FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
            FKQK REEQ E DGTE+ADK+A+LMG+NS++L+K L HPR+KVGNEYVT+GQ+++QV  +
Sbjct: 365  FKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYS 424

Query: 436  VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
            +GAL+K++YE+MF W+V RIN  L+ K  RQ+FIG+LDI GFEI ++NS EQLCINFTNE
Sbjct: 425  IGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNE 484

Query: 496  KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
            KLQQFFN HMFVLEQEEYKKE IEW  I FG+DLQACIDLIEKPMGI+SILEEECMFPKA
Sbjct: 485  KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKA 544

Query: 556  TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
            TD+TFK KL+DNH GKS + QKP+  K K EAHF L+HYAG V YNI GWLEKNKD LNE
Sbjct: 545  TDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNE 604

Query: 616  TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMTN 673
            TVVA++QKSS +L+A+LF +Y + D+    G+ K  +KKG+SFQTV++LH+ENLNKLMTN
Sbjct: 605  TVVALYQKSSLKLMATLFSSYATADTG-DSGKSKGGKKKGSSFQTVSALHRENLNKLMTN 663

Query: 674  LKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQR 733
            L++T PHFVRCI PN  K PG++D  LV+ QLRCNGVLEG RICR+GFPNR+ Y DF+QR
Sbjct: 664  LRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQR 723

Query: 734  YCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERL 793
            Y ILNP   P+ +F+ SRK  E+LL SL+IDH QY+FG TKVFFKAG LG LE +RDERL
Sbjct: 724  YRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL 783

Query: 794  SKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVK 853
            S++ T  QA+A+G+LMRI+F+KI+E RDAL++IQWNIRAFM VKNWPWM+L+FKIKPL+K
Sbjct: 784  SRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLK 843

Query: 854  SSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANV 913
            S+E  +E+A +KEE  ++++ LEKSE +R+EL+ K VSL QEKNDL LQ+QAEQ+ L + 
Sbjct: 844  SAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDA 903

Query: 914  EEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETML 973
            EE+C+ LIK+KIQLEA+VKE++ER+E+EEE+N+ELTA+ RKLEDEC ELKK+IDDLE  L
Sbjct: 904  EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL 963

Query: 974  VKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033
             K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQ LDDL +EE+K++SLS
Sbjct: 964  AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023

Query: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
            K+ +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES+ +LE+ +  L E+L+
Sbjct: 1024 KSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLK 1083

Query: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153
            KKE +++Q NSK+E+E+ L  QLQK +KE Q +I++L+E+LEAERT RAK+E+ R+DL++
Sbjct: 1084 KKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSR 1143

Query: 1154 DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLA 1213
            +L +++ERLEE GG++  Q+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HADS+A
Sbjct: 1144 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVA 1203

Query: 1214 ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATA 1273
            EL  Q++NLQ+VKQKLEK+KS+ +LE+DD+ + +EQ+ +AKAN EK+    E++ +E   
Sbjct: 1204 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRV 1263

Query: 1274 KLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEK 1333
            KL++  +  ND   Q+ KL +E+GE  R+LEEKEALI+QL+R K ++T+Q+EDL+ QLE+
Sbjct: 1264 KLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323

Query: 1334 ETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQ 1393
            E K+++ALAHALQ A+ DCDLLREQYEEE E KAEL R LSK N+E+ QWR KYE + IQ
Sbjct: 1324 EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ 1383

Query: 1394 RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAAR 1453
            RTE+LE+AKK+LA RLQ+A EA+   NA+ +SLE+ +H+LQ E+ D + D+ +  +AAA 
Sbjct: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443

Query: 1454 LDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRE 1513
            LD+KQ    K LA+WKQK+EESQ+ L++SQKE ++LSTEL KLKN YEES+   ET +RE
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1503

Query: 1514 NKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF 1573
            NKNLQEEIS+LT Q+ EG KN+ E+EKV+K +E EK E+Q  LEE E +LE  E KIL  
Sbjct: 1504 NKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRA 1563

Query: 1574 QLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEED 1633
            QLE  + KAE+ERKL+EKDEE+E  +R  Q  +DSLQ+SLD+E +SR EV R+KKKME D
Sbjct: 1564 QLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623

Query: 1634 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1693
            LNEME+QLS ANR  +EA K +  LQ  +KD Q+QLDD+ + N DLKE +A+ ERRN+LL
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683

Query: 1694 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1753
            Q+ELE+LR++ EQTER R+L+E+EL+E +ER+ L ++QNTSL++QKKK+E+D+ ++Q E 
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743

Query: 1754 EEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAE 1813
            EE VQEC+NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQTI DLQ RL EAE
Sbjct: 1744 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1803

Query: 1814 QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
            Q+AL G +KQ+QKLE+RVRELEGELE E +R+AE+ +G R+ ER IKELTYQ EEDKKNL
Sbjct: 1804 QIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNL 1863

Query: 1874 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLK 1933
             R+Q  +DKLQLKV+ YK+Q E AE QAN  LSK++K QHEL+E +ERA++AESQVNKL+
Sbjct: 1864 LRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLR 1923

Query: 1934 IKAREFGKK 1942
             K+R+ G K
Sbjct: 1924 AKSRDIGAK 1932



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 4/149 (2%)

Query: 848  IKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQ 907
            IK L    +  E++A LK    QLQK   +      EL+A+Q    +    +    +  +
Sbjct: 1792 IKDLQHRLDEAEQIA-LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIK 1850

Query: 908  ETLANVEEQCEWLIKSKI---QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKK 964
            E     EE  + L++ +    +L+ +VK    + EE EE  +   ++ RK++ E  E ++
Sbjct: 1851 ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1910

Query: 965  EIDDLETMLVKSEKEKRTTEHKVKNLTEE 993
              D  E+ + K   + R    K K   EE
Sbjct: 1911 RADIAESQVNKLRAKSRDIGAKQKMHDEE 1939


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 2401 bits (6222), Expect = 0.0
 Identities = 1198/1927 (62%), Positives = 1553/1927 (80%), Gaps = 7/1927 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +++  G AA +LR+SE E L  Q    D KK  ++PD +  +++A++  S + G V  ET
Sbjct: 5    EMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIV-SREGGKVTAET 63

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G+++++KED++ Q NPP+F+ IEDMAMLT L+E +VL+ LK RYG WMIYTYSGLFCV
Sbjct: 64   EYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCV 123

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY  EV+AAY+GK+RSEAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 124  TVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAG 183

Query: 202  KTVNSKHIIQYFATIAAMIESRKK-----QGALEDQIMQANTILEAFGNAKTLRNDNSSR 256
            KTVN+K +IQYFA IAA+ +  KK     +G LEDQI+QAN  LEAFGNAKT+RNDNSSR
Sbjct: 184  KTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSR 243

Query: 257  FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
            FGKFIR+HFGA G L+S DI+ YLLEKSRVIFQ   ER+YHIFYQILS +K EL D+LL+
Sbjct: 244  FGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLI 303

Query: 316  SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
            + NP D+ F S G  TV S+DDAEEL+AT+ A D+LGF  +EK   YKLTGAIMHFGNMK
Sbjct: 304  TNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMK 363

Query: 376  FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
            FK K REEQ E DGTE ADK+A+LMG+NS++L+K L HPR+KVGNEYVT+GQ ++QV  A
Sbjct: 364  FKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYA 423

Query: 436  VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
             GAL+K++YERMF W+V RIN  L+ K  RQ+FIG+LDI GFEI ++NS EQLCINFTNE
Sbjct: 424  TGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNE 483

Query: 496  KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
            KLQQFFN HMFVLEQEEYKKE IEW  I FG+DLQACIDLIEKPMGI+SILEEECMFPKA
Sbjct: 484  KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKA 543

Query: 556  TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
            TD+TFK KLFDNH GKS + QKP+  K K EAHF L+HYAG+V YNI GWL+KNKD LNE
Sbjct: 544  TDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNE 603

Query: 616  TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLK 675
            TVV ++QKSS +LL++LF NY   D+ I  G+ K KKG+SFQTV++LH+ENLNKLMTNL+
Sbjct: 604  TVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLR 663

Query: 676  STAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYC 735
            ST PHFVRCI PN  K PG++D  LV+ QLRCNGVLEG RICR+GFPNR+ Y DF+QRY 
Sbjct: 664  STHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYR 723

Query: 736  ILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSK 795
            ILNP   P+ +F+ SRK AE+LL SL+IDH QY+FG TKVFFKAG LG LE +RDERLS+
Sbjct: 724  ILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSR 783

Query: 796  VFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSS 855
            + T  QA+++G L R++++K+LE RD+L++IQWNIRAFM VKNWPWM+L+FKIKPL+KS+
Sbjct: 784  IITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSA 843

Query: 856  EVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE 915
            E  +E+A +KEE  +L++ALEKSE +R+EL+ K VSL QEKNDL LQ+QAEQ+ LA+ EE
Sbjct: 844  EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903

Query: 916  QCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVK 975
            +C+ LIK+KIQLEA+VKE++ER+E+EEE+N+ELTA+ RKLEDEC ELK++IDDLE  L K
Sbjct: 904  RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963

Query: 976  SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKA 1035
             EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQ LDDL  EE+K+++L+KA
Sbjct: 964  VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023

Query: 1036 NLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKK 1095
             +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES+ +LE+ ++ L E L+KK
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083

Query: 1096 ELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDL 1155
            + EL+ +N+++E+E+ L +QLQK +KELQ +I++L+E+LEAERT RAK+E+ R+DL+++L
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143

Query: 1156 ADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAEL 1215
             +++ERLEE GG++  Q+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HADS+AEL
Sbjct: 1144 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1203

Query: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275
              Q++NLQ+VKQKLEK+KS+ +LE+DD+ + +EQ+ +AKAN EK+C   E++++E  +K 
Sbjct: 1204 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA 1263

Query: 1276 DKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKET 1335
            ++  +  NDL +Q+ KL +E+GE  R+L+EKEALI+QL+R K  +T+Q+EDL+ QLE+E 
Sbjct: 1264 EETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEV 1323

Query: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRT 1395
            K+++ALAHALQ A+ DCDLLREQYEEE E KAEL R LSK N+E+ QWR KYE + IQRT
Sbjct: 1324 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1383

Query: 1396 EDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLD 1455
            E+LE+AKK+LA RLQEA EA+   NA+ +SLE+ +H+LQ E+ D + D+ +  +AAA LD
Sbjct: 1384 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 1443

Query: 1456 QKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENK 1515
            +KQ    K LA+WKQK+EESQ+ L++SQKE ++LSTEL KLKN YEES+   ET +RENK
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503

Query: 1516 NLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQL 1575
            NLQEEIS+LT Q+    K + E+EKV+K +E EK E+Q  LEE E +LE  E KIL  QL
Sbjct: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563

Query: 1576 ELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLN 1635
            E  + KAE+ERKL+EKDEE+E  +R     +DSLQ+SLD+E +SR E  R+KKKME DLN
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623

Query: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695
            EME+QLS ANR  +EA K +  LQ  +KD Q+QLDD+ + N DLKE +A+ ERRN+LLQ+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683

Query: 1696 ELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEE 1755
            ELE+LR++ EQTER R+L+E+EL+E +ER+ L ++QNTSL++QKKK++AD++++Q E EE
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEE 1743

Query: 1756 VVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQM 1815
             VQEC+NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQTI DLQ RL EAEQ+
Sbjct: 1744 AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI 1803

Query: 1816 ALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSR 1875
            AL G +KQ+QKLE+RVRELE ELE E +R+AE+ +G R+ ER IKELTYQ EED+KNL R
Sbjct: 1804 ALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLR 1863

Query: 1876 MQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIK 1935
            +Q  +DKLQLKV+ YK+Q E AE QAN  LSK++K QHEL+E +ERA++AESQVNKL+ K
Sbjct: 1864 LQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923

Query: 1936 AREFGKK 1942
            +R+ G K
Sbjct: 1924 SRDIGTK 1930


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 2336 bits (6055), Expect = 0.0
 Identities = 1176/1944 (60%), Positives = 1535/1944 (78%), Gaps = 15/1944 (0%)

Query: 17   ALIKMDLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGT 76
            A   MD+S+LGE+A +LR+   E+  +     DGKK+ W+PD ++AY+EAEVK     G 
Sbjct: 40   ATAMMDVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGR 99

Query: 77   VIVETADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYS 136
            V VET D + L ++E ++Q MNPP F+++EDMAM+THLNEASVLH L++RY +WMIYTYS
Sbjct: 100  VTVETKDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYS 159

Query: 137  GLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTG 196
            GLFCVTINPYKWLPVY   V+AAYKGKRRS++PPHI+AVA+NA+ DML NR+NQS+L TG
Sbjct: 160  GLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITG 219

Query: 197  ESGAGKTVNSKHIIQYFATIAAMIESRKKQ---------GALEDQIMQANTILEAFGNAK 247
            ESGAGKTVN+K +IQYFA +AA+ +   K+         G LEDQI++AN  +EAFGNAK
Sbjct: 220  ESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAK 279

Query: 248  TLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK 307
            TLRNDNSSRFGKFIR+HFG  G L+S DID YLLEKSRVIFQ  GER+YH++YQILSG+K
Sbjct: 280  TLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRK 339

Query: 308  -ELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTG 366
             EL D+LL+S NP D+HFCS G +TV++++D EEL+AT+ AMDILGF  DEK  CYK+ G
Sbjct: 340  PELQDMLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVG 399

Query: 367  AIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRG 426
            A++HFGNMKFKQK REEQ EADGTE+ADKAA+LMG++S +L+K L+HPR++VGNEYVT+G
Sbjct: 400  ALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKG 459

Query: 427  QTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLE 486
            Q++EQV  AVGAL+K+ Y+R+F+WLV+RIN+ LD KL RQFFIG+LDI GFEI E+NS E
Sbjct: 460  QSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFE 519

Query: 487  QLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSIL 546
            QLCINFTNEKLQQFFN HMFVLEQEEYK+E I+WV I FGLDLQ CIDLIEKP+GILSIL
Sbjct: 520  QLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSIL 579

Query: 547  EEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK-KFEAHFELVHYAGVVPYNISGW 605
            EEECMFPKA+D +F+ KL+DNH GKS + Q+P+PDKK K++AHFE+VHYAGVVPY+I GW
Sbjct: 580  EEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGW 639

Query: 606  LEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFG---EKKRKKGASFQTVASL 662
            LEKNKD LNETVV +FQKS NRLLA+L+ENY  + S  P     ++KRKK ASFQTV+ L
Sbjct: 640  LEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQL 699

Query: 663  HKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFP 722
            HKENLNKLMTNL++T PHFVRCI PN NK PG++D +LVL QLRCNGVLEG RICR+GFP
Sbjct: 700  HKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFP 759

Query: 723  NRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFL 782
            NRL Y DF+QRY ILNP   P   F+ SRKA E+LLGSL++DHTQY+FG TKVFFKAG L
Sbjct: 760  NRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLL 819

Query: 783  GQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWM 842
            G LE +RD+RL+KV TL QAR++G+LMR+++Q++L  RDAL  IQWNIRAF AVKNW WM
Sbjct: 820  GVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWM 879

Query: 843  RLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQ 902
            +LFFK+KPL++S++  EE+A L+ E   L+ AL  +E +R+EL+   VS+TQEKNDL LQ
Sbjct: 880  KLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQ 939

Query: 903  LQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFEL 962
            LQAEQ+ LA+ EE+C  LIKSK+QLE +VKELSER+E+EEE+N++L AR RKLEDEC EL
Sbjct: 940  LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTEL 999

Query: 963  KKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDL 1022
            KK+IDDL+  L K+EKEK+ TE+KVKNLTEE+  L+E +++L +  K +QEAHQQ L DL
Sbjct: 1000 KKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL 1059

Query: 1023 HMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLE 1082
              EE+++S+L+KA L+LEQQV++LE +LEQE+K RM+ ER   KLEG+LKL +ES+ +  
Sbjct: 1060 QAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAA 1119

Query: 1083 SSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRA 1142
              ++ L E+L+KK+ ELSQ++ +VE+E+ L AQ+QK +KELQ + ++L+E+LEAER  RA
Sbjct: 1120 QDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARA 1179

Query: 1143 KMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSA 1202
            ++E++RA+  ++L +L+ERLEE GG+S  Q E  +K+E +  +L R++EEA L  E T A
Sbjct: 1180 RVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVA 1239

Query: 1203 SLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCT 1262
            +L+++ A+  AEL  QV++LQ+V+QKLEK+KS+L++EVDDL   VE +TRAKA+AEKLC 
Sbjct: 1240 ALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCR 1299

Query: 1263 LYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTR 1322
             YE++L EA  K++++ +   D + Q+ +L +ESGE  R LEEKE LI+QLSR K+   +
Sbjct: 1300 TYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQ 1359

Query: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQ 1382
             +E+LR QLE+E+K++SALAHA+Q  + DCDLLREQ+EEE E +AEL R LSK NAE+ Q
Sbjct: 1360 SLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQ 1419

Query: 1383 WRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALS 1442
            WR KYE + IQRTE+LE+AKK+LA+RLQEA E +  ANA+ +SLE+A+ +LQ E  D   
Sbjct: 1420 WRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTL 1479

Query: 1443 DLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEE 1502
            +L +  SAAA LD+KQ    +AL + +++ EE Q  L+A+Q+E + L TEL +L++ +EE
Sbjct: 1480 ELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEE 1539

Query: 1503 SIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGA 1562
            ++   ETL+RENKNLQEEIS+LT+QV    K++ E+EK KK +E EK+E+Q  LEE EGA
Sbjct: 1540 ALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGA 1599

Query: 1563 LERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIE 1622
            LE  E+K L  QLEL + KAE++RKL+EKDEE  N RR  Q  ++SLQ+SLD+E ++R E
Sbjct: 1600 LELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNE 1659

Query: 1623 VTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQ 1682
              RLKKKME DLN++ELQL  A RQ +EA  +   +Q Q+K+ Q   D+  +L ++L EQ
Sbjct: 1660 ALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQ 1719

Query: 1683 VAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKL 1742
                ERR SLL +ELE+LR+  EQ ER RRL+E+ELLEATER+NL ++QNT LL+QKKKL
Sbjct: 1720 AQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKL 1779

Query: 1743 EADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTI 1802
            EAD+A++  E EE  QE + AEEKAKKA  +AA ++EELKK+QDT AHLER ++ +EQT+
Sbjct: 1780 EADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTV 1839

Query: 1803 TDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKEL 1862
             +LQ RL EAEQ AL G +KQ+QKLE++VRELE EL+ E ++ AEA +G R+ ER +KEL
Sbjct: 1840 RELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKEL 1899

Query: 1863 TYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERA 1922
             YQAEED+KNL+RMQ  +DKLQ KV++YK+Q E AE QAN  L+KY+K QHEL++ +ERA
Sbjct: 1900 AYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERA 1959

Query: 1923 EVAESQVNKLKIKARE-FGKKVQE 1945
            ++AE+Q NKL+ + R+  G K +E
Sbjct: 1960 DMAETQANKLRARTRDALGPKHKE 1983



 Score =  176 bits (446), Expect = 2e-43
 Identities = 192/859 (22%), Positives = 385/859 (44%), Gaps = 74/859 (8%)

Query: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173
            AQ ++ +  L+ +++ L+  L A    R ++E     +TQ+  DL  +L+     +LA  
Sbjct: 892  AQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQ-AEQDNLADA 950

Query: 1174 E----ITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKL 1229
            E    +  K + + +   +++ E     E  +A L  R                  ++KL
Sbjct: 951  EERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAAR------------------RRKL 992

Query: 1230 EKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQK 1289
            E + ++L+ ++DDL     ++T AKA  EK  T  E ++   T ++  + +    L  +K
Sbjct: 993  EDECTELKKDIDDL-----KLTLAKAEKEKQAT--ENKVKNLTEEMAALDESVARLTKEK 1045

Query: 1290 TKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQ 1349
              L     + L  L+ +E  ++ L++ K    +Q+EDL   LE+E K +     A +K +
Sbjct: 1046 KALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLE 1105

Query: 1350 RDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRL 1409
             D  L +E   +  + K +L   L K ++E+ Q  ++ E+  +   + ++   KEL  R 
Sbjct: 1106 GDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQ-MQKKIKELQARA 1164

Query: 1410 QEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQ----KQLQSGKAL 1465
            +E  E +    A  A +E+ R +   EL +    L +   A+A   +    ++ + G+  
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224

Query: 1466 ADWKQ---KHEESQALLDASQKEVQA-LSTELLKLKNTYEESIVGQETLRRENKNLQEEI 1521
             + ++   +HE + A L   Q E  A L  ++  L+         ++ L +E   L+ E+
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRV-------RQKLEKEKSELRMEV 1277

Query: 1522 SNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK 1581
             +L   V   T+     EK+ +  E++ +E ++ +EE +  L    ++    Q E     
Sbjct: 1278 DDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTE----S 1333

Query: 1582 AELERKLSEKDEEIENFRRKQQCTIDSLQS---SLDSEAKSRIEVTRLKKKMEEDLNEME 1638
             EL R L EK+  I    R +     SL+     L+ E+K++  +    + +  D + + 
Sbjct: 1334 GELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLR 1393

Query: 1639 LQLSCANRQVSEATKSLGQLQIQIKDLQMQLD-DSTQLNSDLKEQVAVAERRNSLLQSEL 1697
             Q        +E  + L +   ++   + + + D+ Q   +L+E       R    +  +
Sbjct: 1394 EQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGV 1453

Query: 1698 EDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVV 1757
            E   +     E+ +   + E  + T  +    +   +L  +++ LE  +   +++ EE+ 
Sbjct: 1454 EAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQ 1513

Query: 1758 QECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMAL 1817
            +E + A+ +++    E   L    ++  + +  L+R  +N+++ I+DL       +Q++L
Sbjct: 1514 RELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDL------TDQVSL 1567

Query: 1818 MGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAE--EDKKNLSR 1875
             G  K IQ+LE   + LEGE + EI+ + E   GA  LE   K L  Q E  + K  + R
Sbjct: 1568 SG--KSIQELEKTKKALEGE-KSEIQAALEEAEGALELEET-KTLRIQLELSQVKAEVDR 1623

Query: 1876 MQTQMDKLQLKVQ-NYKQQVEV------AETQA-NQYLSKYKKQQHELNEVKERAEVAES 1927
               + D+    ++ N+++ VE       AET+A N+ L   KK + +LN+++ +   A  
Sbjct: 1624 KLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATR 1683

Query: 1928 QVNKLKIKAREFGKKVQEE 1946
            Q  + +   R    +++EE
Sbjct: 1684 QATEAQAATRLMQAQLKEE 1702


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 2318 bits (6008), Expect = 0.0
 Identities = 1157/1936 (59%), Positives = 1536/1936 (79%), Gaps = 12/1936 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +L+  GEAA FLR+SE E +  Q    D K   ++ + + ++++  ++ S + G V V+T
Sbjct: 6    ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQ-SREGGKVTVKT 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G +L++K+D++  MNPP+++ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY+ EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
            KTVN+K +IQYFATIA   E +K+       QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 185  KTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNS 244

Query: 255  SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
            SRFGKFIR+HFG  G L+S DI+ YLLEKSRV+FQ   ER+YHIFYQI S +K EL ++L
Sbjct: 245  SRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEML 304

Query: 314  LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
            L++ NP D+ F S G ++V S+DD EEL+AT+ A+DILGF  +EK   YKLTGA+MH+GN
Sbjct: 305  LITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGN 364

Query: 374  MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
            +KFKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT+EQV+
Sbjct: 365  LKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVS 424

Query: 434  CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
             AVGAL+K++YE+MF W+VARIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 425  NAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484

Query: 494  NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
            NEKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544

Query: 554  KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
            KATD +FK KL+D H GKS + QKPK  K K EAHF L+HYAGVV YNI+GWLEKNKD L
Sbjct: 545  KATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPL 604

Query: 614  NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKR---KKGASFQTVASLHKENLNKL 670
            NETVV ++QKS+ + LA LF    + +     G  K+   KKG+SFQTV++L +ENLNKL
Sbjct: 605  NETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKL 664

Query: 671  MTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADF 730
            MTNL+ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ YADF
Sbjct: 665  MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 724

Query: 731  KQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRD 790
            KQRY +LN    P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD
Sbjct: 725  KQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 784

Query: 791  ERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKP 850
            ++L+++ T  QAR +G L R+++Q+++E R+A+  IQ+NIR+FM VK+WPWM+LFFKIKP
Sbjct: 785  DKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKP 844

Query: 851  LVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETL 910
            L+KS+E  +E+A +KEE  +++  L KSE +R+EL+ K V+L +EKNDL LQ+QAE E L
Sbjct: 845  LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904

Query: 911  ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970
            A+ EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE
Sbjct: 905  ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964

Query: 971  TMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030
              L K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQTLDDL  EE+K++
Sbjct: 965  LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024

Query: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090
            +L+KA +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES+ ++E+ ++ L E
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084

Query: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150
            +L+KKE E+S + SK+E+E+ L  QLQK +KELQ +I++L+E++EAER +RAK E++R+D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144

Query: 1151 LTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHAD 1210
            L+++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HAD
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204

Query: 1211 SLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHE 1270
            S+AEL  Q++NLQ+VKQKLEK+KS++++E+DDL + VE +++AK N EK+C   E++L E
Sbjct: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSE 1264

Query: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQ 1330
              +K ++  +L NDL AQ+ +L +ESGEF R+L+EKEAL++QLSR K  FT+QIE+L+ Q
Sbjct: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324

Query: 1331 LEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENN 1390
            LE+E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N E+ QWR KYE +
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETD 1384

Query: 1391 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSA 1450
             IQRTE+LE+AKK+LA RLQ A E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A
Sbjct: 1385 AIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAA 1444

Query: 1451 AARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETL 1510
             A LD+KQ    K LA+WKQK EE+ A L+ASQKE ++L TEL K+KN YEES+   ETL
Sbjct: 1445 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETL 1504

Query: 1511 RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKI 1570
            +RENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q  LEE E +LE  E KI
Sbjct: 1505 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKI 1564

Query: 1571 LHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM 1630
            L  QLEL + K+E++RK++EKDEEI+  +R     ++S+QS+LD+E +SR +  RLKKKM
Sbjct: 1565 LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1624

Query: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRN 1690
            E DLNEME+QL+ ANR  +EA ++    Q  +KD Q+ LDD+ +   DLKEQ+A+ ERR 
Sbjct: 1625 EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRA 1684

Query: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQ 1750
            +LLQ+E+E+LR+  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D+++MQ
Sbjct: 1685 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQ 1744

Query: 1751 KEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA 1810
             E E+++QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL 
Sbjct: 1745 GEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1804

Query: 1811 EAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDK 1870
            EAEQ+AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+
Sbjct: 1805 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDR 1864

Query: 1871 KNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVN 1930
            KN+ R+Q  +DKLQ KV++YK+Q E AE Q+N  L+K++K QHEL E +ERA++AESQVN
Sbjct: 1865 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924

Query: 1931 KLKIKAREFGKKVQEE 1946
            KL++K+RE   KV  E
Sbjct: 1925 KLRVKSREVHTKVISE 1940


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 2318 bits (6008), Expect = 0.0
 Identities = 1157/1936 (59%), Positives = 1536/1936 (79%), Gaps = 12/1936 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +L+  GEAA FLR+SE E +  Q    D K   ++ + + ++++  ++ S + G V V+T
Sbjct: 6    ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQ-SREGGKVTVKT 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G +L++K+D++  MNPP+++ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY+ EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
            KTVN+K +IQYFATIA   E +K+       QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 185  KTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNS 244

Query: 255  SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
            SRFGKFIR+HFG  G L+S DI+ YLLEKSRV+FQ   ER+YHIFYQI S +K EL ++L
Sbjct: 245  SRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEML 304

Query: 314  LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
            L++ NP D+ F S G ++V S+DD EEL+AT+ A+DILGF  +EK   YKLTGA+MH+GN
Sbjct: 305  LITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGN 364

Query: 374  MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
            +KFKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT+EQV+
Sbjct: 365  LKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVS 424

Query: 434  CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
             AVGAL+K++YE+MF W+VARIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 425  NAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484

Query: 494  NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
            NEKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544

Query: 554  KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
            KATD +FK KL+D H GKS + QKPK  K K EAHF L+HYAGVV YNI+GWLEKNKD L
Sbjct: 545  KATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPL 604

Query: 614  NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKR---KKGASFQTVASLHKENLNKL 670
            NETVV ++QKS+ + LA LF    + +     G  K+   KKG+SFQTV++L +ENLNKL
Sbjct: 605  NETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKL 664

Query: 671  MTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADF 730
            MTNL+ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ YADF
Sbjct: 665  MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 724

Query: 731  KQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRD 790
            KQRY +LN    P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD
Sbjct: 725  KQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 784

Query: 791  ERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKP 850
            ++L+++ T  QAR +G L R+++Q+++E R+A+  IQ+NIR+FM VK+WPWM+LFFKIKP
Sbjct: 785  DKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKP 844

Query: 851  LVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETL 910
            L+KS+E  +E+A +KEE  +++  L KSE +R+EL+ K V+L +EKNDL LQ+QAE E L
Sbjct: 845  LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904

Query: 911  ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970
            A+ EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE
Sbjct: 905  ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964

Query: 971  TMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030
              L K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQTLDDL  EE+K++
Sbjct: 965  LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024

Query: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090
            +L+KA +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES+ ++E+ ++ L E
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084

Query: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150
            +L+KKE E+S + SK+E+E+ L  QLQK +KELQ +I++L+E++EAER +RAK E++R+D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144

Query: 1151 LTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHAD 1210
            L+++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HAD
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204

Query: 1211 SLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHE 1270
            S+AEL  Q++NLQ+VKQKLEK+KS++++E+DDL + VE +++AK N EK+C   E++L E
Sbjct: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSE 1264

Query: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQ 1330
              +K ++  +L NDL AQ+ +L +ESGEF R+L+EKEAL++QLSR K  FT+QIE+L+ Q
Sbjct: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324

Query: 1331 LEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENN 1390
            LE+E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N E+ QWR KYE +
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETD 1384

Query: 1391 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSA 1450
             IQRTE+LE+AKK+LA RLQ A E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A
Sbjct: 1385 AIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAA 1444

Query: 1451 AARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETL 1510
             A LD+KQ    K LA+WKQK EE+ A L+ASQKE ++L TEL K+KN YEES+   ETL
Sbjct: 1445 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETL 1504

Query: 1511 RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKI 1570
            +RENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q  LEE E +LE  E KI
Sbjct: 1505 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKI 1564

Query: 1571 LHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM 1630
            L  QLEL + K+E++RK++EKDEEI+  +R     ++S+QS+LD+E +SR +  RLKKKM
Sbjct: 1565 LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1624

Query: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRN 1690
            E DLNEME+QL+ ANR  +EA ++    Q  +KD Q+ LDD+ +   DLKEQ+A+ ERR 
Sbjct: 1625 EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRA 1684

Query: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQ 1750
            +LLQ+E+E+LR+  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D+++MQ
Sbjct: 1685 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQ 1744

Query: 1751 KEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA 1810
             E E+++QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL 
Sbjct: 1745 GEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1804

Query: 1811 EAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDK 1870
            EAEQ+AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+
Sbjct: 1805 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDR 1864

Query: 1871 KNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVN 1930
            KN+ R+Q  +DKLQ KV++YK+Q E AE Q+N  L+K++K QHEL E +ERA++AESQVN
Sbjct: 1865 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924

Query: 1931 KLKIKAREFGKKVQEE 1946
            KL++K+RE   KV  E
Sbjct: 1925 KLRVKSREVHTKVISE 1940


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 2315 bits (5998), Expect = 0.0
 Identities = 1156/1934 (59%), Positives = 1539/1934 (79%), Gaps = 10/1934 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +++  GEAA FLR+SE E +  Q    D K   ++ D + +Y++A V+ S + G V  +T
Sbjct: 6    EMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQ-SREGGKVTAKT 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G ++++KED++  MNPP+++ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   EAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY  EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
            KTVN+K +IQYFATIA   E +K+       QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 185  KTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNS 244

Query: 255  SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
            SRFGKFIR+HFGA G L+S DI+ YLLEKSRV FQ   ER+YHIFYQILS +K EL ++L
Sbjct: 245  SRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEML 304

Query: 314  LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
            L++ NP DF F S G +TV S+DD EEL+AT+ A+DILGF  DEK   YKLTGA+MH+GN
Sbjct: 305  LITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGN 364

Query: 374  MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
            MKFKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNE+VT+GQT++QV 
Sbjct: 365  MKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVY 424

Query: 434  CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
             AVGAL+K++YE+MF W+V RIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 425  NAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484

Query: 494  NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
            NEKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544

Query: 554  KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
            KATD +FK KL++ H GKS + QKPKP K K EAHF LVHYAG V YNI+GWL+KNKD L
Sbjct: 545  KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPL 604

Query: 614  NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK-RKKGASFQTVASLHKENLNKLMT 672
            NETVV ++QKS+ + LA LF    + ++    G+K  +KKG+SFQTV++L +ENLNKLMT
Sbjct: 605  NETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664

Query: 673  NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732
            NL+ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ YADFKQ
Sbjct: 665  NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724

Query: 733  RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792
            RY +LN    P+ +F+ S+KA+E+LLGS+EIDHTQY+FG TKVFFKAG LG LE +RDE+
Sbjct: 725  RYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEK 784

Query: 793  LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852
            L+++ T  QA  +G LMR++F+K++E R+++  IQ+NIRAFM VK+WPWM+L+FKIKPL+
Sbjct: 785  LAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLL 844

Query: 853  KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
            KS+E  +E+A +KEE  + ++ L K+E +R+EL+ K V+L QEKNDL LQ+QAE + LA+
Sbjct: 845  KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904

Query: 913  VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972
             EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE  
Sbjct: 905  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964

Query: 973  LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
            L K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQTLDDL MEE+K+++L
Sbjct: 965  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024

Query: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
            +KA  KLEQQVD+LEG+LEQE+K  M+ ER   KLEG+LKL +ES  + E+ ++ L E+L
Sbjct: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL 1084

Query: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
            +KKE E+S +  K+E+E+ L  QLQK +KELQ +I++L+E++EAER +RAK E++R+DL+
Sbjct: 1085 KKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144

Query: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212
            ++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EE+TL  E T+A+L+K+HADS+
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSV 1204

Query: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272
            AEL  Q+++LQ+VKQKLEK+KS+L++E++DL + +E +++AKAN EK+C   E++L E  
Sbjct: 1205 AELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264

Query: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332
             K ++  +L N+L+AQK +L +ESGEF R+L+EK+A+++QLSR K  FT+QIE+L+ QLE
Sbjct: 1265 TKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLE 1324

Query: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392
            +ETK++S LAHALQ A+ DCDLLREQYEEEQE KAEL R +SK N+E+ QWR KYE + I
Sbjct: 1325 EETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAI 1384

Query: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452
            QRTE+LE+AKK+LA RLQ+A E +   N++ ASLE+ + +LQ E+ D + D+ +  +A  
Sbjct: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACI 1444

Query: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512
             LD+KQ    K LA+WKQK+EE+QA L+ASQKE ++LSTEL K+KN YEES+   ETL+R
Sbjct: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKR 1504

Query: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572
            ENKNLQ+EIS+LT Q+ EG K++ E+EKVKK ++ EK+E+Q +LEE E +LE  E KIL 
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564

Query: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632
             QLEL + K+E++RK++EKDEE++  +R     ++S+QS+LD+E +SR +  R+KKKME 
Sbjct: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEG 1624

Query: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692
            DLNEME+QL+ ANRQ +EA ++L   Q  +KD Q+ LDD+ +   DLKEQ+A+ ERR +L
Sbjct: 1625 DLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANL 1684

Query: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
            +Q+E+E+LR+  E+TERGR+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D++++Q E
Sbjct: 1685 MQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744

Query: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812
             E++VQE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL EA
Sbjct: 1745 MEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1804

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872
            EQ+AL G +KQIQKLE+RVRELE E+E E + + EA +G R+ ER +KELTYQ EED+KN
Sbjct: 1805 EQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKN 1864

Query: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932
            + R+Q  +DKLQ KV+ YK+Q E AE Q+N  L+K++K QHEL E KERA++AESQVNKL
Sbjct: 1865 ILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKL 1924

Query: 1933 KIKAREFGKKVQEE 1946
            ++K+RE   KV  E
Sbjct: 1925 RVKSREVHTKVISE 1938


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 2311 bits (5990), Expect = 0.0
 Identities = 1160/1934 (59%), Positives = 1522/1934 (78%), Gaps = 10/1934 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +++  GEAA +LR+ E E +  Q    D KK C++ D +  Y++  ++  E+D  VIV+T
Sbjct: 6    EMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTREND-KVIVKT 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
             D   L++  D++  MNPP+F+ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   LDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY+ EV+AAY+GK+R EAPPHIF++++NA+Q ML +R+NQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKK------QGALEDQIMQANTILEAFGNAKTLRNDNSS 255
            KTVN+K +IQYFATIA   + +K+      QG LEDQI+QAN +LEAFGNAKT+RNDNSS
Sbjct: 185  KTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244

Query: 256  RFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLL 314
            RFGKFIR+HFGA G L+S DI+ YLLEKSRV FQ + ER+YHIFYQI+S +K EL DLLL
Sbjct: 245  RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLL 304

Query: 315  VSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNM 374
            +S NP DF F S G VTV S+DD+EELLAT+ A+DILGF  +EK G YKLTGA+MH+GNM
Sbjct: 305  ISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNM 364

Query: 375  KFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTC 434
            KFKQK REEQ E DGTE ADKA +LMG+NS+E++K L  PR+KVGNEYVT+GQ ++QVT 
Sbjct: 365  KFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTN 424

Query: 435  AVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTN 494
            +VGAL+K++YE+MF W+V RIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFTN
Sbjct: 425  SVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTN 484

Query: 495  EKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPK 554
            EKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFPK
Sbjct: 485  EKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPK 544

Query: 555  ATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLN 614
            ATD +FK KL+D H GKS + QKPKP K K EAHF LVHYAG V YNI+GWL+KNKD LN
Sbjct: 545  ATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLN 604

Query: 615  ETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMT 672
            ETVV ++QKSS +LL+ LF NY   ++    G KK  +KKG+SFQTV+++ +ENLNKLMT
Sbjct: 605  ETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMT 664

Query: 673  NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732
            NL+ST PHFVRC+ PN  K PG++D YLV+ QLRCNGVLEG RICR+GFP+R+ YADFKQ
Sbjct: 665  NLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724

Query: 733  RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792
            RY ILN    P+ +F+ S+ A+E+LL S+++D  Q+RFG TKVFFKAG LG LE +RDE+
Sbjct: 725  RYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEK 784

Query: 793  LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852
            L  + T  QA  +G LMR++F+K++E RD++  IQ+NIR+FM VK+WPWM LFFKIKPL+
Sbjct: 785  LVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLL 844

Query: 853  KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
            KS+E  +E+A +KE+  + ++ L +SE +R+EL+ K VSL QEKNDL LQ+Q+E E L +
Sbjct: 845  KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904

Query: 913  VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972
             EE+CE LIKSKI LEA+VKEL+ER+EEEEE+NSEL A+ R LED+C  LK++IDDLE  
Sbjct: 905  AEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELT 964

Query: 973  LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
            L K EKEK  TE+KVKNL+EE+  L E+ISKL +  K +QEAHQQTLDDL +EE+K++ L
Sbjct: 965  LTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGL 1024

Query: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
             K N KLEQQ D+LEG+LEQE+K R + ER   KLEG+LK+++ES+ +LE+ ++ + E+L
Sbjct: 1025 IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKL 1084

Query: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
            +KKE ELSQ+ +K+++E+    Q QK +KELQ +I++L+E++EAE T RAK+E++R+DL 
Sbjct: 1085 KKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLA 1144

Query: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212
            ++L +++ERLEE  G++ AQ+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+ ADS+
Sbjct: 1145 RELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSV 1204

Query: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272
            AEL  Q++NLQ+VKQKLEK+KS+L++E+DD+ + +E ++++K+N E+ C   E++  E  
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIK 1264

Query: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332
            AK ++ TQL +DL  QK +L +++GE   R+EEKE+LI+QL++ K   T+Q+E+L+ Q+E
Sbjct: 1265 AKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQME 1324

Query: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392
            +ETK+++A+AHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + I
Sbjct: 1325 EETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAI 1384

Query: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452
            QRTE+LE+AKK+LA RLQEA E    AN++ ASLE+ + +LQ E+ D + DL +  +A A
Sbjct: 1385 QRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACA 1444

Query: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512
             LD+KQ    K LA+WKQK +ESQA L+A+QKE ++LSTEL K++N YEE +   ETLRR
Sbjct: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504

Query: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572
            ENKNLQEEIS+LT Q+ E  KNL E EK KKL+E+EK+++QV LEE EG+LE  ESKIL 
Sbjct: 1505 ENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILR 1564

Query: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632
             QLEL + K+EL+RK+ EKDEEIE  +R  Q   ++LQS LD+E +SR +  RLKKKME 
Sbjct: 1565 VQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEG 1624

Query: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692
            DLNEME+QL  +NRQ++E  K L  +Q Q+KD Q+ LDD+ + N DLKEQ+A+ ERRN L
Sbjct: 1625 DLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGL 1684

Query: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
            L  ELE+++   EQTER RRLSE+ELL+A++R+ L ++QNTSL++ KKKLEAD+A+ Q E
Sbjct: 1685 LLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAE 1744

Query: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812
             E  +QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EA
Sbjct: 1745 VENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872
            EQ+AL G +KQIQKLE+RVRELE EL+ E +R AEA +GA + ER +KE+TYQAEED KN
Sbjct: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864

Query: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932
            + R+Q  +DKLQ KV++YK+Q E AE QAN  LS+ ++ QHEL E  ERA++AESQVNKL
Sbjct: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKL 1924

Query: 1933 KIKAREFGKKVQEE 1946
            + K+R+ G +  EE
Sbjct: 1925 RAKSRDVGSQKMEE 1938


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 2310 bits (5985), Expect = 0.0
 Identities = 1150/1931 (59%), Positives = 1529/1931 (79%), Gaps = 7/1931 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +++  GEAA +LR+SE E +  Q    D K   ++ + + +Y+++ ++ S++ G V V+T
Sbjct: 8    EMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQ-SKEGGKVTVKT 66

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G +L+++ED++  MNPP+++ IEDMAM+THL+E  VL+ LK RY  WMIYTYSGLFCV
Sbjct: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY+ EV+AAY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186

Query: 202  KTVNSKHIIQYFATIAAM-----IESRKKQGALEDQIMQANTILEAFGNAKTLRNDNSSR 256
            KTVN+K +IQYFATIA        ES K QG LEDQI+ AN +LEAFGNAKT+RNDNSSR
Sbjct: 187  KTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSR 246

Query: 257  FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
            FGKFIR+HFG  G L+S DI+ YLLEKSRV FQ   ER+YHIFYQI S +K +L ++LL+
Sbjct: 247  FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLI 306

Query: 316  SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
            + NP D+ F S G +TV S+DD EEL+AT+ A+DILGF P+EK   YKLTGA+MH+GNMK
Sbjct: 307  TTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMK 366

Query: 376  FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
            FKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT++QV  A
Sbjct: 367  FKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNA 426

Query: 436  VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
            VGAL+K++YE+MF W+V RIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFTNE
Sbjct: 427  VGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486

Query: 496  KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
            KLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKP+GI SILEEECMFPKA
Sbjct: 487  KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKA 546

Query: 556  TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
            TD +FK KL+D H GKS + QKPK  K K EAHF L+HYAG V YNI+GWL+KNKD LN+
Sbjct: 547  TDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLND 606

Query: 616  TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLK 675
            TVV ++QKS+ + LASLF  Y S ++     +  +KKG+SFQTV++L +ENLNKLMTNL+
Sbjct: 607  TVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLR 666

Query: 676  STAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYC 735
            ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ Y DFKQRY 
Sbjct: 667  STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYK 726

Query: 736  ILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSK 795
            +LN    P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RDE+L++
Sbjct: 727  VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQ 786

Query: 796  VFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSS 855
            + T  QA  +G LMR+++QK+L+ R+AL  IQ+N+RAFM VK+WPWM+LFFKIKPL+KS+
Sbjct: 787  IITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSA 846

Query: 856  EVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE 915
            E  +E+A +KEE  + +  L KSE +R+EL+ K V+L +EKNDL LQ+Q+E ++LA+ EE
Sbjct: 847  ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 906

Query: 916  QCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVK 975
            +CE LIK+KIQLEA++KE++ER EEEEEIN+ELTA+ RKLEDEC ELKK+IDDLE  L K
Sbjct: 907  RCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 966

Query: 976  SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKA 1035
             EKEK  TE+KVKNLTEE+  L+E I+KL++  K +QE HQQTLDDL  EE+K++ L+KA
Sbjct: 967  VEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKA 1026

Query: 1036 NLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKK 1095
              KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES  ++E+ ++ L E+L KK
Sbjct: 1027 KTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKK 1086

Query: 1096 ELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDL 1155
            E E+S + SK+E+E+ +  QLQK +KELQ +I++L E++EAER +RAK E++R+DL+++L
Sbjct: 1087 EFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSREL 1146

Query: 1156 ADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAEL 1215
             +++ERLEE GG++ AQ+E+ KK+E +FQKL RD+EEATL  E   A+L+K+HADS+AEL
Sbjct: 1147 EEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAEL 1206

Query: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275
              Q++NLQ+VKQKLEK+KS+L++E DDL +  E +++AK N EK+C   E+++ E   K 
Sbjct: 1207 GEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE 1266

Query: 1276 DKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKET 1335
            ++  +L NDL AQ+ +L +E+GE+ R+L+EK+AL++QLSR K   T+QIE+L+ QLE+ET
Sbjct: 1267 EEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEET 1326

Query: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRT 1395
            K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + IQRT
Sbjct: 1327 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1386

Query: 1396 EDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLD 1455
            E+LE+AKK+LA RLQEA E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A A LD
Sbjct: 1387 EELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALD 1446

Query: 1456 QKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENK 1515
            +KQ    K L++WKQK+EE+QA L+ASQKE ++LSTEL K+KN YEES+   ETLRRENK
Sbjct: 1447 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENK 1506

Query: 1516 NLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQL 1575
            NLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q  LEE E +LE  E KIL  QL
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566

Query: 1576 ELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLN 1635
            EL + K+E++RK++EKDEEI+  +R     ++++QS+LD+E +SR +  R+KKKME DLN
Sbjct: 1567 ELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLN 1626

Query: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695
            EME+QL+ ANR  +E+ ++    Q  +K+ Q+ LDD+ +   DLKEQ+A+ ERR +LLQ+
Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQA 1686

Query: 1696 ELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEE 1755
            E+E+L +  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE DV+++Q E EE
Sbjct: 1687 EIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE 1746

Query: 1756 VVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQM 1815
            V+QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EAEQ+
Sbjct: 1747 VIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1806

Query: 1816 ALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSR 1875
            AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+KN+ R
Sbjct: 1807 ALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLR 1866

Query: 1876 MQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIK 1935
            +Q  +DKLQ KV++YK+Q E AE Q+N  LSK++K QHEL E +ERA++AESQVNKL++K
Sbjct: 1867 LQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVK 1926

Query: 1936 AREFGKKVQEE 1946
            +RE   K+  E
Sbjct: 1927 SREVHTKISAE 1937


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 2308 bits (5981), Expect = 0.0
 Identities = 1144/1934 (59%), Positives = 1535/1934 (79%), Gaps = 10/1934 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            +++  GEAA FLR+SE E +  Q    D K   ++ D + ++++A V+ S + G V  +T
Sbjct: 6    EMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQ-SREGGKVTAKT 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
              G ++++K+D++  MNPP+++ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   EAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY  EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254
            KTVN+K +IQYFATIA   E +K+       QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 185  KTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNS 244

Query: 255  SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313
            SRFGKFIR+HFG  G L+S DI+ YLLEKSRV FQ   ER+YHIFYQI+S +K +L ++L
Sbjct: 245  SRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEML 304

Query: 314  LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373
            L++ NP D+ F S G +TV S+DD EEL+AT+ A++ILGF  DE+   YKLTGA+MH+GN
Sbjct: 305  LITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGN 364

Query: 374  MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433
            MKFKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT++QV 
Sbjct: 365  MKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVY 424

Query: 434  CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493
             AVGAL+K++Y++MF W+V RIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 425  NAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484

Query: 494  NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553
            NEKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544

Query: 554  KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613
            KATD +FK KL++ H GKS + QKPKP K K EAHF L+HYAG V YNI+GWL+KNKD L
Sbjct: 545  KATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPL 604

Query: 614  NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK-RKKGASFQTVASLHKENLNKLMT 672
            NETVV ++QKS+ + LA LF      ++    G+K  +KKG+SFQTV++L +ENLNKLMT
Sbjct: 605  NETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMT 664

Query: 673  NLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQ 732
            NL+ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ YADFKQ
Sbjct: 665  NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQ 724

Query: 733  RYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDER 792
            RY +LN    P+ +F+ S+KA+E+LLGS++IDHTQY+FG TKVFFKAG LG LE +RDE+
Sbjct: 725  RYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEK 784

Query: 793  LSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLV 852
            L+++ T  QA  +G L R+++QK++E R+++  IQ+N+RAFM VK+WPWM+L+FKIKPL+
Sbjct: 785  LAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLL 844

Query: 853  KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
            KS+E  +E+A +KEE  + ++ L K+E +R+EL+ K V+L QEKNDL LQ+QAE ++LA+
Sbjct: 845  KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904

Query: 913  VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 972
             EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE  
Sbjct: 905  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964

Query: 973  LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
            L K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQTLDDL  EE+K+++L
Sbjct: 965  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024

Query: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
            +KA +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES  ++E+ ++ L E+L
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL 1084

Query: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
            +KKE E+S + SK+E+E+ L  QLQK +KELQ +I++L+E++EAER +RAK E++R+DL+
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144

Query: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL 1212
            ++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HADS+
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204

Query: 1213 AELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEAT 1272
            AEL  Q++NLQ+VKQKLEK+KS++++E+DDL + +E +++AK N EK+C   E++L E  
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264

Query: 1273 AKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLE 1332
             K ++  +L NDL AQ+ +L +ESGE+ R+L+EK+ L++QLSR K  FT+QIE+L+ QLE
Sbjct: 1265 TKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE 1324

Query: 1333 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1392
            +E K++SALAHALQ ++ DCDLLREQYEEEQE KAEL R +SK N+E+ QWR KYE + I
Sbjct: 1325 EEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAI 1384

Query: 1393 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1452
            QRTE+LE+AKK+LA RLQ+A E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A A
Sbjct: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACA 1444

Query: 1453 RLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRR 1512
             LD+KQ    K LA+WKQK EE+ A L+ASQKE ++LSTEL K+KN YEES+   ETL+R
Sbjct: 1445 ALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504

Query: 1513 ENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILH 1572
            ENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK+E+Q  LEE E +LE  E KIL 
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILR 1564

Query: 1573 FQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEE 1632
             QLEL + K+E++RK++EKDEEI+  +R     ++S+QS+LD+E +SR +  RLKKKME 
Sbjct: 1565 IQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEG 1624

Query: 1633 DLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSL 1692
            DLNEME+QL+ ANR  +EA ++    Q  +KD Q+ LDD+ +   DLKEQ+A+ ERR +L
Sbjct: 1625 DLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 1684

Query: 1693 LQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
            LQ+E+E+LR+  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D++++Q E
Sbjct: 1685 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744

Query: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEA 1812
             E+++QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EA
Sbjct: 1745 MEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN 1872
            EQ+AL G +KQIQKLE+RVRELEGE+E E +R+ EA +G R+ ER +KELTYQ EED+KN
Sbjct: 1805 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKN 1864

Query: 1873 LSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKL 1932
            + R+Q  +DKLQ KV++YK+Q E AE Q+N  LSK+++ QHEL E +ERA++AESQVNKL
Sbjct: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKL 1924

Query: 1933 KIKAREFGKKVQEE 1946
            ++K+RE   K+  E
Sbjct: 1925 RVKSREVHTKIISE 1938


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 2300 bits (5960), Expect = 0.0
 Identities = 1156/1926 (60%), Positives = 1511/1926 (78%), Gaps = 11/1926 (0%)

Query: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
            ++   G AA FLR+SE E +  Q    D K  C++ D +  Y + ++K S+D G V VET
Sbjct: 6    EMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQD-GKVTVET 64

Query: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
             D  +L +K + +  MNPP+F+ IEDMAMLTHLNE +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 65   EDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCV 124

Query: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
            T+NPYKWLPVY  EV+  Y+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 125  TVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184

Query: 202  KTVNSKHIIQYFATIAAMIESRKKQ-----GALEDQIMQANTILEAFGNAKTLRNDNSSR 256
            KTVN+K +IQYFATIAA  +  KK+     G LEDQI+ AN +LEAFGNAKT+RNDNSSR
Sbjct: 185  KTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSR 244

Query: 257  FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
            FGKFIR+HFG  G L+S DI+ YLLEKSRV FQ   ER+YHIFYQILS +K EL +LLL+
Sbjct: 245  FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLI 304

Query: 316  SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
            + NP D+ F S G + V S+DDAEELLAT+ A+DILGF P+EK G YKLTGA+MH+GNMK
Sbjct: 305  TTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMK 364

Query: 376  FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
            FKQK REEQ E DGTE ADK A+LMG+NSS+L+K L  PR+KVGNEYVT+GQT++QV  A
Sbjct: 365  FKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHA 424

Query: 436  VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
            V ALSKS+YE++F W+V RIN+ LD KL RQ FIG+LDI GFEI EYNSLEQLCINFTNE
Sbjct: 425  VNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNE 484

Query: 496  KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
            KLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFPKA
Sbjct: 485  KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKA 544

Query: 556  TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
            TD +FK KL+D H GKS + QKPK  K + EAHF L+HYAG V Y++SGWLEKNKD LNE
Sbjct: 545  TDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNE 604

Query: 616  TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMTN 673
            TVV ++QKSSNRLLA L+  + + D+    G+KK  +KKG+SFQTV++L +ENLNKLM+N
Sbjct: 605  TVVGLYQKSSNRLLAHLYATFATADA--DSGKKKVAKKKGSSFQTVSALFRENLNKLMSN 662

Query: 674  LKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQR 733
            L++T PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFPNR+ Y DFKQR
Sbjct: 663  LRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQR 722

Query: 734  YCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERL 793
            Y +LN    P+ +F+ S+KA E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD+RL
Sbjct: 723  YRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRL 782

Query: 794  SKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVK 853
            +K+ T  QA  +G LMR++FQK+++ R+++  IQ+NIR+FM VK+WPWM+LFFKIKPL+K
Sbjct: 783  AKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLK 842

Query: 854  SSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANV 913
            S+E  +E+A +KEE  + +  L KSE +R+EL+ K V+L QEKNDL LQ+QAE E L + 
Sbjct: 843  SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDA 902

Query: 914  EEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETML 973
            EE+C+ LIK+K QLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE  L
Sbjct: 903  EERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 962

Query: 974  VKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033
             K EKEK  TE+KVKNLTEE+  L+E I+KL R  K +QEAHQQ LDDL  EE+K++SL+
Sbjct: 963  AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLN 1022

Query: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
            K   KLEQQV++LE +LEQE+K R++ ER   KLEG+LKL +ES+ +LE+ ++ L E L+
Sbjct: 1023 KTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLK 1082

Query: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153
            KK+ E  Q+ SKVE+E+ L  Q QK +KELQ +I++L+E++EAER TRAK E++R+D  +
Sbjct: 1083 KKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYAR 1142

Query: 1154 DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLA 1213
            +L +L+ERLEE GG +  Q+E+ KK+E +F KL RD+EEATL  E   A+L+K+HADS+A
Sbjct: 1143 ELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVA 1202

Query: 1214 ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATA 1273
            EL  Q++NLQ+VKQKLEK+KS+ +LE+DDL + +E ++++KAN EK+C   E++L EA  
Sbjct: 1203 ELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARG 1262

Query: 1274 KLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEK 1333
            K +++ +  ++L  QK++L +E+GE  R+LEEKE++++QLSR K  FT+Q E+L+ QLE+
Sbjct: 1263 KNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEE 1322

Query: 1334 ETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQ 1393
            E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + IQ
Sbjct: 1323 ENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1382

Query: 1394 RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAAR 1453
            RTE+LE+AKK+LA RLQ++ E +   NA+ ASLE+ + +LQ E+ D + D+ +  S AA 
Sbjct: 1383 RTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442

Query: 1454 LDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRE 1513
            LD+KQ    K LA+WK K EESQA L+AS KE ++LSTEL KLKN YEE++   ET++RE
Sbjct: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502

Query: 1514 NKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF 1573
            NKNL++EI++LT Q+ E  K + E+EK +K IE EK ++Q+ LEE E ALE  E+KIL  
Sbjct: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRI 1562

Query: 1574 QLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEED 1633
            QLEL + K+E++RK++EKDEEIE  +R  Q T++++QS+LD+E +SR E  RLKKKME D
Sbjct: 1563 QLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGD 1622

Query: 1634 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1693
            LNE+E+QLS ANRQ +E  K L  +Q Q+KD Q+ LDD+ +   DLKEQ+A+ ERR +LL
Sbjct: 1623 LNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLL 1682

Query: 1694 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1753
            Q+E+E+LR+  EQTER R+L+E+ELL++ ER+ L +TQNTSL+  KKKLE D+ ++Q E 
Sbjct: 1683 QAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEV 1742

Query: 1754 EEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAE 1813
            E+  ++ +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EAE
Sbjct: 1743 EDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1802

Query: 1814 QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
            Q+AL G +KQIQKLE+R+RELE ELEGE +++ E+ +G R+ ER +KELTYQ+EED+KN+
Sbjct: 1803 QLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNV 1862

Query: 1874 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLK 1933
             R+Q  +DKLQ+KV++YK+Q E A+ QAN +L+K++K QHEL E +ERA++AESQVNKL+
Sbjct: 1863 LRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLR 1922

Query: 1934 IKAREF 1939
             K R+F
Sbjct: 1923 AKTRDF 1928



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 115/492 (23%), Positives = 210/492 (42%), Gaps = 64/492 (13%)

Query: 859  EEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCE 918
            +E   L  E  +L+ A E++  Q E +K +  +L QE  DL  Q+    +T+  +E+  +
Sbjct: 1473 KESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRK 1532

Query: 919  WLIKSKIQLEARVKELSERVEEEE----EINSELTARGRKLEDECFELKKEIDDL----- 969
             +   K  ++  ++E    +E EE     I  ELT    +++ +  E  +EI+ L     
Sbjct: 1533 QIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQ 1592

Query: 970  ---ETMLVKSEKEKRTTEHKVKNLTEEVEFLNE---DISKLNRAA----KVVQEAHQQTL 1019
               ETM    + E R+    ++   +    LNE    +S  NR A    K ++    Q  
Sbjct: 1593 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 1652

Query: 1020 D-DLHMEE---------EKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
            D  LH+++         E+L+ + +    L+ +V+EL   LEQ  +AR   E+EL  L+ 
Sbjct: 1653 DTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL--LDS 1710

Query: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
            N     E ++ L +    L    +K E +L Q+ S+VE+        ++  K+  T    
Sbjct: 1711 N-----ERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM 1765

Query: 1130 LKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRD 1189
            + E+L+ E+ T A +ER + +L Q + DL  RL+E    +L      K  + + QKL   
Sbjct: 1766 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL------KGGKKQIQKLET- 1818

Query: 1190 MEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQ 1249
                                  + ELE ++E  Q+   +  K     +  V +L  + E+
Sbjct: 1819 ---------------------RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857

Query: 1250 MTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEAL 1309
              +     + L    + ++     + ++  + AN    +  K   E  E   R +  E+ 
Sbjct: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917

Query: 1310 INQLSREKSNFT 1321
            +N+L  +  +FT
Sbjct: 1918 VNKLRAKTRDFT 1929



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 78/320 (24%), Positives = 151/320 (47%), Gaps = 28/320 (8%)

Query: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695
            E E +++    +  +    L + + + K+L+ +L    Q  +DL+ QV          Q+
Sbjct: 845  ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQV----------QA 894

Query: 1696 ELEDLRSLQEQTE---RGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
            E E+L   +E+ +   + +   E ++ E TER       N  L ++K+KLE + + ++K+
Sbjct: 895  ESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 954

Query: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME----QTITDLQKR 1808
             +++       E++      +  NL+EEL    +TIA L R ++ ++    Q + DLQ  
Sbjct: 955  IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQ-- 1012

Query: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQ 1865
               AE+  +    K   KLE +V +LE  LE E +   + +R  R+LE  +K   E    
Sbjct: 1013 ---AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069

Query: 1866 AEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVA 1925
             E DK+ L     ++ K   +    + +VE  +T   Q+  K K+ Q  + E++E  E  
Sbjct: 1070 LENDKQQLDE---RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 1126

Query: 1926 ESQVNKLKIKAREFGKKVQE 1945
             +   K + +  ++ ++++E
Sbjct: 1127 RATRAKTEKQRSDYARELEE 1146


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 1255 bits (3247), Expect = 0.0
 Identities = 713/1907 (37%), Positives = 1115/1907 (58%), Gaps = 24/1907 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            KK  WIP   + +  A +K    D  ++    +G+   + +D IQ+MNPP+F  +EDMA 
Sbjct: 33   KKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAE 92

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH LK RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 93   LTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPP 152

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227
            HI+A++ +A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK     G
Sbjct: 153  HIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPG 212

Query: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
             LE Q++QAN ILE+FGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR +
Sbjct: 213  ELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAV 272

Query: 288  FQQAGERNYHIFYQILSGQKE--LHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345
             Q   ER +HIFYQ+LSG  E    DLLL   N  ++ F S G + +    D +    T 
Sbjct: 273  RQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQQDKDNFQETM 330

Query: 346  QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405
            +AM I+GF  +E     K+  +++ FGN+ FK++   +Q        A K   L+G+N  
Sbjct: 331  EAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVM 390

Query: 406  ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALD-AKLS 464
            E  + ++ PRIKVG +YV + QT EQ   AV AL+K+ YER+F+WLV RIN+ALD  K  
Sbjct: 391  EFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQ 450

Query: 465  RQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIG 524
               FIGILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I 
Sbjct: 451  GASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFID 510

Query: 525  FGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPD 581
            FGLDLQ CIDLIE+P    G+L++L+EEC FPKATD TF  KL     G     QKP+  
Sbjct: 511  FGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQL 569

Query: 582  KKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY----- 636
            K K  A F ++HYAG V Y    WL KN D LN+ V  +  +SS+R +A L+++      
Sbjct: 570  KDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVG 627

Query: 637  ---MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693
               ++  +   FG   + K   F+TV  L+KE+L KLM  L++T P+FVRCI PN  K  
Sbjct: 628  LDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRA 687

Query: 694  GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753
            G LDP+LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P   PK  F+  ++A
Sbjct: 688  GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA 746

Query: 754  AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813
             E ++ +LE+D   YR G +K+FF+AG L  LE  RD +++ +   FQA  +G L R  F
Sbjct: 747  CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806

Query: 814  QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873
             K  ++  AL ++Q N  A++ +++W W R+F K+KPL++ +   EE+    EE  ++++
Sbjct: 807  AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866

Query: 874  ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933
               K E + EE++ K   L +EKN L  QLQAE E  A  EE    L   K +LE  + +
Sbjct: 867  KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926

Query: 934  LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993
            L  RVEEEEE N  L    +K++    +L++++D+ E    K + EK T E K+K + EE
Sbjct: 927  LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986

Query: 994  VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053
            +  L +  SK  +  K++++   +    L  EEEK  +L+K   K E  + +LE  L++E
Sbjct: 987  ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046

Query: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113
             K R   E+   KL+G     ++ +  L++    L  +L KKE EL    ++ ++E    
Sbjct: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106

Query: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173
                K V+ELQ QI +L+E  E+E+ +R K E+++ DL+++L  L   LE+   ++ AQ 
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233
            E+  K+E +  +L + +EE T + E     +++RHA +L EL  Q+E  ++ K  LEK+K
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226

Query: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293
              L+ +  +L   V+ + + KA +E      + ++ E  AK+ +  +L  +LA + +KL 
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286

Query: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353
            +E       LEE E    + +++ ++   Q++D +  L++ET+ +  L+  +++ + + +
Sbjct: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             L+EQ EEE+E +  L + +  + +++   + K +++ +   E LE+AKK+L    +  +
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDAEALS 1405

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
            + +         LE+ +++LQ EL D   DL   R  A+ L++KQ +  + LA+ K    
Sbjct: 1406 QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISA 1465

Query: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533
                  D ++ E +   T+ L L    EE++  +E   R+NK L+ ++ +L +   +  K
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525

Query: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593
            N+ E+EK K+ +E++  E++  LEE E  L+  E   L  ++ +   KA+ ER L  +DE
Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585

Query: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653
            + E  +R     +  L++ L+ E K R      KKKME DL ++E Q+  AN+   E  K
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645

Query: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713
             L +LQ Q+KD Q +L+++     ++  Q   +E++   L++E+  L+     +ER RR 
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705

Query: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1773
            +E+E  E  + I    +  ++LL +K++LEA +A++++E EE     +   ++ +K  ++
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765

Query: 1774 AANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRE 1833
               L+ EL  ++      +  R+ +E+   +L+ +L E E       +  I  LE+++ +
Sbjct: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825

Query: 1834 LEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQ 1893
            LE +LE E +  A A +  RR E+ +KE+  Q E+++++  + + QM+K   +++  K+Q
Sbjct: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885

Query: 1894 VEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFG 1940
            +E AE +A +  +  +K Q EL++  E  E    +V+ LK + R  G
Sbjct: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG 1932



 Score =  192 bits (489), Expect = 2e-48
 Identities = 179/924 (19%), Positives = 404/924 (43%), Gaps = 94/924 (10%)

Query: 1025 EEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESS 1084
            +EE+L +  +  LK++++  ++EG LE+  +       E + L   L+   E     E  
Sbjct: 850  QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909

Query: 1085 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKM 1144
            +  LA + ++ E  L  + S+VE E+     LQ   K++Q  I+DL+E+L+ E   R K+
Sbjct: 910  RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 969

Query: 1145 ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASL 1204
            + E+      +  + E +  +   +   ++  K  E +  +    + E     +   A +
Sbjct: 970  QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL-AKI 1028

Query: 1205 KKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLY 1264
            + +    +++LE +++  ++ +Q+LEK K  L  E  DL  ++ ++       +      
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK 1088

Query: 1265 EERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQI 1324
            EE L  A A+ D  T   N+      +L ++  E     E ++A  N+  ++K + + ++
Sbjct: 1089 EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148

Query: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384
            E L+ +LE    + +A      K +++   L++  EEE +                    
Sbjct: 1149 EALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETK-------------------- 1188

Query: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444
                         ++D ++  A  L+E +E +  A    A+LE+ +  L+ +  +   ++
Sbjct: 1189 --------NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240

Query: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESI 1504
              ++   A  + K+ +    + +   K  E   L     ++   L  EL  +    EE+ 
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE 1300

Query: 1505 VGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALE 1564
                   ++  +L+ ++ +    ++E T+    +    + +EEEK  +Q   EE E A +
Sbjct: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK 1360

Query: 1565 RNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVT 1624
              E ++L  Q +L + K +++  L                TI+SL+ +            
Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLG---------------TIESLEEA------------ 1393

Query: 1625 RLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVA 1684
              KKK+ +D   +  +L        +  K+  +LQ ++ DL + LD   Q+ S+L+++  
Sbjct: 1394 --KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK-- 1449

Query: 1685 VAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEA 1744
                     Q + + L + +E++   R   E +  EA  R             +K+    
Sbjct: 1450 ---------QKKFDQLLA-EEKSISARYAEERDRAEAEAR-------------EKETKAL 1486

Query: 1745 DVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDT---IAHLERTRENMEQT 1801
             +AR  +EA E  +E +   ++ +      A++ + +  K D    +  LE+++  +EQ 
Sbjct: 1487 SLARALEEALEAKEEFERQNKQLR------ADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540

Query: 1802 ITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIR-RSAEAQRGARRLERCIK 1860
            + +++ +L E E   L  +     +LE  ++ ++ + E +++ R  + +   R L + ++
Sbjct: 1541 VEEMRTQLEELED-ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599

Query: 1861 ELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKE 1920
            EL  + E+++K  +       K+++ +++ + Q+E A    ++ + + +K Q ++ + + 
Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659

Query: 1921 RAEVAESQVNKLKIKAREFGKKVQ 1944
              E A +  +++  +++E  KK++
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLK 1683



 Score =  112 bits (280), Expect = 4e-24
 Identities = 109/481 (22%), Positives = 207/481 (43%), Gaps = 30/481 (6%)

Query: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
            ++E+QA   ELLK+K    +     E + R+++ L EE + L  Q++  T+   E E+++
Sbjct: 851  EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910

Query: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQ 1602
              +  +K E++  L + E  +E  E +    Q E  + +A ++    + DEE E  R+K 
Sbjct: 911  ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKL 969

Query: 1603 QC---TIDSLQSSLDSEA----KSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSL 1655
            Q    T ++    ++ E         +  + KK ME+ + E   QL+    +     K  
Sbjct: 970  QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIR 1029

Query: 1656 GQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSE 1715
             + ++ I DL+ +L    +   +L++     +   + LQ ++ +L++  ++ +      E
Sbjct: 1030 NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKE 1089

Query: 1716 EELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAA 1775
            EEL  A  R +       + L   ++L+A +A +Q++ E        AE++ +  + E  
Sbjct: 1090 EELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149

Query: 1776 NLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELE 1835
             L  EL+   DT A  +  R   EQ + +L+K L E  +      +   Q+  + + EL 
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELS 1209

Query: 1836 GELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL-----------SRMQTQMDKLQ 1884
             +LE   R  A  ++  + LE            D K L           +  + +  KL 
Sbjct: 1210 EQLEQAKRFKANLEKNKQGLET-----------DNKELACEVKVLQQVKAESEHKRKKLD 1258

Query: 1885 LKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQ 1944
             +VQ    +V   +    +   K  K Q+EL+ V    E AE +  K    A     ++Q
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ 1318

Query: 1945 E 1945
            +
Sbjct: 1319 D 1319



 Score = 38.1 bits (87), Expect = 0.085
 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 9/140 (6%)

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
            ++  L    +++ K++ +  ++EGELE   R+  +       L   ++   EL  +AEE 
Sbjct: 850  QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
            +  L+  + +++++   + + + +VE  E +     ++ KK Q  + +++E+ +  E   
Sbjct: 910  RARLAAKKQELEEI---LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966

Query: 1930 NKL---KIKAREFGKKVQEE 1946
             KL   K+ A    KK++EE
Sbjct: 967  QKLQLEKVTAEAKIKKMEEE 986


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 1241 bits (3212), Expect = 0.0
 Identities = 708/1907 (37%), Positives = 1109/1907 (58%), Gaps = 30/1907 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            K+  W+P  +  +  A +K  + D  V+    +G+ +++ +D IQ+MNPP+F  +EDMA 
Sbjct: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV +NPYK LP+Y ++++  YKGK+R E PP
Sbjct: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227
            HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + +K     G
Sbjct: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITG 212

Query: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
             LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I
Sbjct: 213  ELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272

Query: 288  FQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345
             Q   ER +HIFY +++G KE    DLLL   N  ++ F S G V + +  D E    T 
Sbjct: 273  RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETV 330

Query: 346  QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405
            +AM I+GF  +E+    K+  +++  GN+ FK++   +Q        A K   LMGIN +
Sbjct: 331  EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVT 390

Query: 406  ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSR 465
            +  + ++ PRIKVG + V + QT EQ   AV AL+K+ YER+F+W++ R+N+ALD K  R
Sbjct: 391  DFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-KTHR 449

Query: 466  Q--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
            Q   F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I
Sbjct: 450  QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509

Query: 524  GFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580
             FGLDLQ CI+LIE+P    G+L++L+EEC FPKATD +F  KL     G     QKPK 
Sbjct: 510  DFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQ 568

Query: 581  DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY---- 636
             K K E  F ++HYAG V YN S WL KN D LN+ V ++   SS++ +A L+++     
Sbjct: 569  LKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626

Query: 637  ------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690
                    T+S++P   K +K    F+TV  L+KE L KLMT L++T P+FVRCI PN  
Sbjct: 627  GLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684

Query: 691  KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750
            K  G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL     PK  F+  
Sbjct: 685  KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDG 743

Query: 751  RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810
            ++A   ++ +LE+D   YR G +K+FF+ G L  LE  RD +++ V   FQA  +G L R
Sbjct: 744  KQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLAR 803

Query: 811  IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQ 870
              F K  ++  A+ +IQ N  A++ ++NW W RLF K+KPL++ +   EE+   ++E  +
Sbjct: 804  KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQK 863

Query: 871  LQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEAR 930
             ++  +K+E + +EL+ K   LT+EKN L  QLQAE E  A  EE    L   K +LE  
Sbjct: 864  TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923

Query: 931  VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNL 990
            + E+  R+EEEE+   +L A  +K+  +  +L++++++ E    K + EK T E K+K L
Sbjct: 924  LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983

Query: 991  TEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGAL 1050
             +E+  +++  +KL++  K+++E       +L  EEEK  +L+K   K E  + ELE  L
Sbjct: 984  EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043

Query: 1051 EQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEK 1110
            ++E K+R   E+   KLEG+     E + +L++    L  +L KKE EL    +++++E 
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103

Query: 1111 GLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSL 1170
                   K ++EL+  I DL+E L++ER  R K E+++ DL ++L  L   LE+   S+ 
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTA 1163

Query: 1171 AQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLE 1230
             Q E+  K+E +   L + ++E T   E     ++++HA ++ EL  Q+E  ++ K  L+
Sbjct: 1164 TQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 1231 KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKT 1290
            K+K  L+ E  DL   +  + +AK   E      E ++ E  +K     +   +L  +  
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 1291 KLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQR 1350
            KL +E       L E E    +L+++ ++ + Q++D +  L++ET+ +  ++  L++ + 
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQ 1410
            + + L++Q +EE E K  L R +S +N ++   + K + +     E LE+ KK     ++
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIE 1402

Query: 1411 EAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470
               +      A    LE+ +++LQ EL D + DL   R   + L++KQ +  + LA+ K 
Sbjct: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1462

Query: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVRE 1530
               +     D ++ E +   T+ L L    EE++  +E L R NK L+ E+ +L +   +
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522

Query: 1531 GTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE 1590
              KN+ E+EK K+ +E +  E++  LEE E  L+  E   L  ++ +   K + ER L  
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582

Query: 1591 KDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSE 1650
            +DE+ E  RR+ Q  +   ++ L+ E K R      KKK+E DL ++ELQ   A +   E
Sbjct: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642

Query: 1651 ATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERG 1710
            A K L +LQ Q+KD Q +L+D+     ++       E++   L+++L  L+      ER 
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702

Query: 1711 RRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKA 1770
            R+ ++ E  E  E +    +   +L  +K++LEA +A++++E EE     +   ++ +KA
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762

Query: 1771 AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
              +A  LS EL  ++ T    E  R+ +E+   +L+ +L E E       +  I  LE++
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822

Query: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNY 1890
            + +LE ++E E R    A +  ++ ++ +KE+  Q E+++K   + + Q +K   +V+  
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882

Query: 1891 KQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
            K+Q+E AE ++ +  +  +K Q EL+E  E  E    +VN LK K R
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)

Query: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
            ++E+QA   EL K K   +++    + L +++  L EE + L  Q++  T+   E E+++
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599
              +  +K E++  L E E  LE  E +    Q E   + +   +LE +L E++   +  +
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656
             ++   +  I  L+  +        ++++ +K +EE ++++   L+    +    TK   
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716
            + +  I +L+++L    +   +L++     E   S    ++ DL++   + +      EE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776
            EL  A  R++    Q  + L + ++LE  ++ +Q++ +        AE++ +    E   
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836
            L  EL+   D+ A  +  R   EQ +T L+K L E  +      ++  QK    V EL  
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210

Query: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896
            +LE   R  A   +  + LE+   +L  +     +    ++ +  KL+ +VQ  + +   
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270

Query: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945
             E    +   K  K Q+E+  V      AE +  KL         ++Q+
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
            ++  +     ++QK + R ++ E EL+   ++ ++       L+  ++   EL  +AEE 
Sbjct: 850  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
            +  L+  + +++++  +++   ++ E    Q      K  +Q  +L E  E  E A  ++
Sbjct: 910  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969

Query: 1930 NKLKIKAREFGKKVQEE 1946
               K+ A    KK+++E
Sbjct: 970  QLEKVTAEAKIKKLEDE 986


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 1241 bits (3212), Expect = 0.0
 Identities = 708/1907 (37%), Positives = 1109/1907 (58%), Gaps = 30/1907 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            K+  W+P  +  +  A +K  + D  V+    +G+ +++ +D IQ+MNPP+F  +EDMA 
Sbjct: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV +NPYK LP+Y ++++  YKGK+R E PP
Sbjct: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227
            HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + +K     G
Sbjct: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITG 212

Query: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
             LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I
Sbjct: 213  ELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272

Query: 288  FQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345
             Q   ER +HIFY +++G KE    DLLL   N  ++ F S G V + +  D E    T 
Sbjct: 273  RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETV 330

Query: 346  QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405
            +AM I+GF  +E+    K+  +++  GN+ FK++   +Q        A K   LMGIN +
Sbjct: 331  EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVT 390

Query: 406  ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSR 465
            +  + ++ PRIKVG + V + QT EQ   AV AL+K+ YER+F+W++ R+N+ALD K  R
Sbjct: 391  DFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-KTHR 449

Query: 466  Q--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
            Q   F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I
Sbjct: 450  QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509

Query: 524  GFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580
             FGLDLQ CI+LIE+P    G+L++L+EEC FPKATD +F  KL     G     QKPK 
Sbjct: 510  DFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQ 568

Query: 581  DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY---- 636
             K K E  F ++HYAG V YN S WL KN D LN+ V ++   SS++ +A L+++     
Sbjct: 569  LKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626

Query: 637  ------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690
                    T+S++P   K +K    F+TV  L+KE L KLMT L++T P+FVRCI PN  
Sbjct: 627  GLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684

Query: 691  KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750
            K  G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL     PK  F+  
Sbjct: 685  KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDG 743

Query: 751  RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810
            ++A   ++ +LE+D   YR G +K+FF+ G L  LE  RD +++ V   FQA  +G L R
Sbjct: 744  KQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLAR 803

Query: 811  IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQ 870
              F K  ++  A+ +IQ N  A++ ++NW W RLF K+KPL++ +   EE+   ++E  +
Sbjct: 804  KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQK 863

Query: 871  LQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEAR 930
             ++  +K+E + +EL+ K   LT+EKN L  QLQAE E  A  EE    L   K +LE  
Sbjct: 864  TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923

Query: 931  VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNL 990
            + E+  R+EEEE+   +L A  +K+  +  +L++++++ E    K + EK T E K+K L
Sbjct: 924  LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983

Query: 991  TEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGAL 1050
             +E+  +++  +KL++  K+++E       +L  EEEK  +L+K   K E  + ELE  L
Sbjct: 984  EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043

Query: 1051 EQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEK 1110
            ++E K+R   E+   KLEG+     E + +L++    L  +L KKE EL    +++++E 
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103

Query: 1111 GLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSL 1170
                   K ++EL+  I DL+E L++ER  R K E+++ DL ++L  L   LE+   S+ 
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTA 1163

Query: 1171 AQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLE 1230
             Q E+  K+E +   L + ++E T   E     ++++HA ++ EL  Q+E  ++ K  L+
Sbjct: 1164 TQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 1231 KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKT 1290
            K+K  L+ E  DL   +  + +AK   E      E ++ E  +K     +   +L  +  
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 1291 KLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQR 1350
            KL +E       L E E    +L+++ ++ + Q++D +  L++ET+ +  ++  L++ + 
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQ 1410
            + + L++Q +EE E K  L R +S +N ++   + K + +     E LE+ KK     ++
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIE 1402

Query: 1411 EAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470
               +      A    LE+ +++LQ EL D + DL   R   + L++KQ +  + LA+ K 
Sbjct: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1462

Query: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVRE 1530
               +     D ++ E +   T+ L L    EE++  +E L R NK L+ E+ +L +   +
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522

Query: 1531 GTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE 1590
              KN+ E+EK K+ +E +  E++  LEE E  L+  E   L  ++ +   K + ER L  
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582

Query: 1591 KDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSE 1650
            +DE+ E  RR+ Q  +   ++ L+ E K R      KKK+E DL ++ELQ   A +   E
Sbjct: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642

Query: 1651 ATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERG 1710
            A K L +LQ Q+KD Q +L+D+     ++       E++   L+++L  L+      ER 
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702

Query: 1711 RRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKA 1770
            R+ ++ E  E  E +    +   +L  +K++LEA +A++++E EE     +   ++ +KA
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762

Query: 1771 AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
              +A  LS EL  ++ T    E  R+ +E+   +L+ +L E E       +  I  LE++
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822

Query: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNY 1890
            + +LE ++E E R    A +  ++ ++ +KE+  Q E+++K   + + Q +K   +V+  
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882

Query: 1891 KQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
            K+Q+E AE ++ +  +  +K Q EL+E  E  E    +VN LK K R
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)

Query: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
            ++E+QA   EL K K   +++    + L +++  L EE + L  Q++  T+   E E+++
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599
              +  +K E++  L E E  LE  E +    Q E   + +   +LE +L E++   +  +
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656
             ++   +  I  L+  +        ++++ +K +EE ++++   L+    +    TK   
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716
            + +  I +L+++L    +   +L++     E   S    ++ DL++   + +      EE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776
            EL  A  R++    Q  + L + ++LE  ++ +Q++ +        AE++ +    E   
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836
            L  EL+   D+ A  +  R   EQ +T L+K L E  +      ++  QK    V EL  
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210

Query: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896
            +LE   R  A   +  + LE+   +L  +     +    ++ +  KL+ +VQ  + +   
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270

Query: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945
             E    +   K  K Q+E+  V      AE +  KL         ++Q+
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
            ++  +     ++QK + R ++ E EL+   ++ ++       L+  ++   EL  +AEE 
Sbjct: 850  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
            +  L+  + +++++  +++   ++ E    Q      K  +Q  +L E  E  E A  ++
Sbjct: 910  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969

Query: 1930 NKLKIKAREFGKKVQEE 1946
               K+ A    KK+++E
Sbjct: 970  QLEKVTAEAKIKKLEDE 986


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 1239 bits (3205), Expect = 0.0
 Identities = 708/1914 (36%), Positives = 1109/1914 (57%), Gaps = 37/1914 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            K+  W+P  +  +  A +K  + D  V+    +G+ +++ +D IQ+MNPP+F  +EDMA 
Sbjct: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV +NPYK LP+Y ++++  YKGK+R E PP
Sbjct: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---- 226
            HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + +K      
Sbjct: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQ 212

Query: 227  ------GALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYL 280
                  G LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YL
Sbjct: 213  GPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYL 272

Query: 281  LEKSRVIFQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDA 338
            LEKSR I Q   ER +HIFY +++G KE    DLLL   N  ++ F S G V + +  D 
Sbjct: 273  LEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDD 330

Query: 339  EELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAF 398
            E    T +AM I+GF  +E+    K+  +++  GN+ FK++   +Q        A K   
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 399  LMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRA 458
            LMGIN ++  + ++ PRIKVG + V + QT EQ   AV AL+K+ YER+F+W++ R+N+A
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 459  LDAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKE 516
            LD K  RQ   F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E
Sbjct: 451  LD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 509

Query: 517  SIEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSV 573
             IEW  I FGLDLQ CI+LIE+P    G+L++L+EEC FPKATD +F  KL     G   
Sbjct: 510  GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHP 568

Query: 574  HLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF 633
              QKPK  K K E  F ++HYAG V YN S WL KN D LN+ V ++   SS++ +A L+
Sbjct: 569  KFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626

Query: 634  ENY----------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVR 683
            ++             T+S++P   K +K    F+TV  L+KE L KLMT L++T P+FVR
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVR 684

Query: 684  CINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFP 743
            CI PN  K  G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL     P
Sbjct: 685  CIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIP 744

Query: 744  KSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQAR 803
            K  F+  ++A   ++ +LE+D   YR G +K+FF+ G L  LE  RD +++ V   FQA 
Sbjct: 745  KG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAM 803

Query: 804  AQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAG 863
             +G L R  F K  ++  A+ +IQ N  A++ ++NW W RLF K+KPL++ +   EE+  
Sbjct: 804  CRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA 863

Query: 864  LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKS 923
             ++E  + ++  +K+E + +EL+ K   LT+EKN L  QLQAE E  A  EE    L   
Sbjct: 864  KEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923

Query: 924  KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTT 983
            K +LE  + E+  R+EEEE+   +L A  +K+  +  +L++++++ E    K + EK T 
Sbjct: 924  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983

Query: 984  EHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQV 1043
            E K+K L +E+  +++  +KL++  K+++E       +L  EEEK  +L+K   K E  +
Sbjct: 984  EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043

Query: 1044 DELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMN 1103
             ELE  L++E K+R   E+   KLEG+     E + +L++    L  +L KKE EL    
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103

Query: 1104 SKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLE 1163
            +++++E        K ++EL+  I DL+E L++ER  R K E+++ DL ++L  L   LE
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163

Query: 1164 EVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQ 1223
            +   S+  Q E+  K+E +   L + ++E T   E     ++++HA ++ EL  Q+E  +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223

Query: 1224 QVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAN 1283
            + K  L+K+K  L+ E  DL   +  + +AK   E      E ++ E  +K     +   
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 1284 DLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAH 1343
            +L  +  KL +E       L E E    +L+++ ++ + Q++D +  L++ET+ +  ++ 
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343

Query: 1344 ALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKK 1403
             L++ + + + L++Q +EE E K  L R +S +N ++   + K + +     E LE+ KK
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKK 1402

Query: 1404 ELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGK 1463
                 ++   +      A    LE+ +++LQ EL D + DL   R   + L++KQ +  +
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462

Query: 1464 ALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISN 1523
             LA+ K    +     D ++ E +   T+ L L    EE++  +E L R NK L+ E+ +
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522

Query: 1524 LTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
            L +   +  KN+ E+EK K+ +E +  E++  LEE E  L+  E   L  ++ +   K +
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582

Query: 1584 LERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSC 1643
             ER L  +DE+ E  RR+ Q  +   ++ L+ E K R      KKK+E DL ++ELQ   
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1642

Query: 1644 ANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSL 1703
            A +   EA K L +LQ Q+KD Q +L+D+     ++       E++   L+++L  L+  
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702

Query: 1704 QEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA 1763
                ER R+ ++ E  E  E +    +   +L  +K++LEA +A++++E EE     +  
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762

Query: 1764 EEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQ 1823
             ++ +KA  +A  LS EL  ++ T    E  R+ +E+   +L+ +L E E       +  
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822

Query: 1824 IQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKL 1883
            I  LE+++ +LE ++E E R    A +  ++ ++ +KE+  Q E+++K   + + Q +K 
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882

Query: 1884 QLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
              +V+  K+Q+E AE ++ +  +  +K Q EL+E  E  E    +VN LK K R
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)

Query: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
            ++E+QA   EL K K   +++    + L +++  L EE + L  Q++  T+   E E+++
Sbjct: 858  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599
              +  +K E++  L E E  LE  E +    Q E   + +   +LE +L E++   +  +
Sbjct: 918  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977

Query: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656
             ++   +  I  L+  +        ++++ +K +EE ++++   L+    +    TK   
Sbjct: 978  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716
            + +  I +L+++L    +   +L++     E   S    ++ DL++   + +      EE
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097

Query: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776
            EL  A  R++    Q  + L + ++LE  ++ +Q++ +        AE++ +    E   
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157

Query: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836
            L  EL+   D+ A  +  R   EQ +T L+K L E  +      ++  QK    V EL  
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217

Query: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896
            +LE   R  A   +  + LE+   +L  +     +    ++ +  KL+ +VQ  + +   
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277

Query: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945
             E    +   K  K Q+E+  V      AE +  KL         ++Q+
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
            ++  +     ++QK + R ++ E EL+   ++ ++       L+  ++   EL  +AEE 
Sbjct: 857  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
            +  L+  + +++++  +++   ++ E    Q      K  +Q  +L E  E  E A  ++
Sbjct: 917  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976

Query: 1930 NKLKIKAREFGKKVQEE 1946
               K+ A    KK+++E
Sbjct: 977  QLEKVTAEAKIKKLEDE 993


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 1239 bits (3205), Expect = 0.0
 Identities = 708/1914 (36%), Positives = 1109/1914 (57%), Gaps = 37/1914 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            K+  W+P  +  +  A +K  + D  V+    +G+ +++ +D IQ+MNPP+F  +EDMA 
Sbjct: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV +NPYK LP+Y ++++  YKGK+R E PP
Sbjct: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---- 226
            HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + +K      
Sbjct: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQ 212

Query: 227  ------GALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYL 280
                  G LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YL
Sbjct: 213  GPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYL 272

Query: 281  LEKSRVIFQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDA 338
            LEKSR I Q   ER +HIFY +++G KE    DLLL   N  ++ F S G V + +  D 
Sbjct: 273  LEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDD 330

Query: 339  EELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAF 398
            E    T +AM I+GF  +E+    K+  +++  GN+ FK++   +Q        A K   
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 399  LMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRA 458
            LMGIN ++  + ++ PRIKVG + V + QT EQ   AV AL+K+ YER+F+W++ R+N+A
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 459  LDAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKE 516
            LD K  RQ   F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E
Sbjct: 451  LD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 509

Query: 517  SIEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSV 573
             IEW  I FGLDLQ CI+LIE+P    G+L++L+EEC FPKATD +F  KL     G   
Sbjct: 510  GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHP 568

Query: 574  HLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF 633
              QKPK  K K E  F ++HYAG V YN S WL KN D LN+ V ++   SS++ +A L+
Sbjct: 569  KFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626

Query: 634  ENY----------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVR 683
            ++             T+S++P   K +K    F+TV  L+KE L KLMT L++T P+FVR
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVR 684

Query: 684  CINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFP 743
            CI PN  K  G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL     P
Sbjct: 685  CIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIP 744

Query: 744  KSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQAR 803
            K  F+  ++A   ++ +LE+D   YR G +K+FF+ G L  LE  RD +++ V   FQA 
Sbjct: 745  KG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAM 803

Query: 804  AQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAG 863
             +G L R  F K  ++  A+ +IQ N  A++ ++NW W RLF K+KPL++ +   EE+  
Sbjct: 804  CRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA 863

Query: 864  LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKS 923
             ++E  + ++  +K+E + +EL+ K   LT+EKN L  QLQAE E  A  EE    L   
Sbjct: 864  KEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923

Query: 924  KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTT 983
            K +LE  + E+  R+EEEE+   +L A  +K+  +  +L++++++ E    K + EK T 
Sbjct: 924  KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983

Query: 984  EHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQV 1043
            E K+K L +E+  +++  +KL++  K+++E       +L  EEEK  +L+K   K E  +
Sbjct: 984  EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043

Query: 1044 DELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMN 1103
             ELE  L++E K+R   E+   KLEG+     E + +L++    L  +L KKE EL    
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103

Query: 1104 SKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLE 1163
            +++++E        K ++EL+  I DL+E L++ER  R K E+++ DL ++L  L   LE
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163

Query: 1164 EVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQ 1223
            +   S+  Q E+  K+E +   L + ++E T   E     ++++HA ++ EL  Q+E  +
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223

Query: 1224 QVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAN 1283
            + K  L+K+K  L+ E  DL   +  + +AK   E      E ++ E  +K     +   
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 1284 DLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAH 1343
            +L  +  KL +E       L E E    +L+++ ++ + Q++D +  L++ET+ +  ++ 
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343

Query: 1344 ALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKK 1403
             L++ + + + L++Q +EE E K  L R +S +N ++   + K + +     E LE+ KK
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKK 1402

Query: 1404 ELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGK 1463
                 ++   +      A    LE+ +++LQ EL D + DL   R   + L++KQ +  +
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462

Query: 1464 ALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISN 1523
             LA+ K    +     D ++ E +   T+ L L    EE++  +E L R NK L+ E+ +
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522

Query: 1524 LTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
            L +   +  KN+ E+EK K+ +E +  E++  LEE E  L+  E   L  ++ +   K +
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582

Query: 1584 LERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSC 1643
             ER L  +DE+ E  RR+ Q  +   ++ L+ E K R      KKK+E DL ++ELQ   
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADS 1642

Query: 1644 ANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSL 1703
            A +   EA K L +LQ Q+KD Q +L+D+     ++       E++   L+++L  L+  
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702

Query: 1704 QEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA 1763
                ER R+ ++ E  E  E +    +   +L  +K++LEA +A++++E EE     +  
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762

Query: 1764 EEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQ 1823
             ++ +KA  +A  LS EL  ++ T    E  R+ +E+   +L+ +L E E       +  
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822

Query: 1824 IQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKL 1883
            I  LE+++ +LE ++E E R    A +  ++ ++ +KE+  Q E+++K   + + Q +K 
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882

Query: 1884 QLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
              +V+  K+Q+E AE ++ +  +  +K Q EL+E  E  E    +VN LK K R
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)

Query: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
            ++E+QA   EL K K   +++    + L +++  L EE + L  Q++  T+   E E+++
Sbjct: 858  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599
              +  +K E++  L E E  LE  E +    Q E   + +   +LE +L E++   +  +
Sbjct: 918  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977

Query: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656
             ++   +  I  L+  +        ++++ +K +EE ++++   L+    +    TK   
Sbjct: 978  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716
            + +  I +L+++L    +   +L++     E   S    ++ DL++   + +      EE
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097

Query: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776
            EL  A  R++    Q  + L + ++LE  ++ +Q++ +        AE++ +    E   
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157

Query: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836
            L  EL+   D+ A  +  R   EQ +T L+K L E  +      ++  QK    V EL  
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217

Query: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896
            +LE   R  A   +  + LE+   +L  +     +    ++ +  KL+ +VQ  + +   
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277

Query: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945
             E    +   K  K Q+E+  V      AE +  KL         ++Q+
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)

Query: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
            ++  +     ++QK + R ++ E EL+   ++ ++       L+  ++   EL  +AEE 
Sbjct: 857  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
            +  L+  + +++++  +++   ++ E    Q      K  +Q  +L E  E  E A  ++
Sbjct: 917  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976

Query: 1930 NKLKIKAREFGKKVQEE 1946
               K+ A    KK+++E
Sbjct: 977  QLEKVTAEAKIKKLEDE 993


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 1236 bits (3197), Expect = 0.0
 Identities = 711/1904 (37%), Positives = 1110/1904 (58%), Gaps = 27/1904 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            KK  W+P  ++ +  A +K    +  ++    +G+ + + +D IQ+MNPP+F  +EDMA 
Sbjct: 29   KKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAE 88

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH LK RY   +IYTYSGLFCV INPYK LP+Y +E++  YKGK+R E PP
Sbjct: 89   LTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPP 148

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALE 230
            HI+A+ + A++ M+ +RE+QSIL TGESGAGKT N+K +IQY A +A+  +S+K QG LE
Sbjct: 149  HIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELE 208

Query: 231  DQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQ 290
             Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I Q 
Sbjct: 209  RQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQA 268

Query: 291  AGERNYHIFYQILSGQKE--LHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAM 348
              ER +HIFY +LSG  E    DLLL   N   + F S G VT+    D +    T +AM
Sbjct: 269  KEERTFHIFYYLLSGAGEHLKTDLLLEPYN--KYRFLSNGHVTIPGQQDKDMFQETMEAM 326

Query: 349  DILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELV 408
             I+G   +E+ G  ++   ++  GN+ FK++   +Q        A K + L+GIN ++  
Sbjct: 327  RIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFT 386

Query: 409  KCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQ-- 466
            + ++ PRIKVG +YV + QT EQ   A+ AL+K+ YERMF+WLV RIN+ALD K  RQ  
Sbjct: 387  RGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD-KTKRQGA 445

Query: 467  FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFG 526
             FIGILDI GFEI + NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I FG
Sbjct: 446  SFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG 505

Query: 527  LDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK 583
            LDLQ CIDLIEKP    GIL++L+EEC FPKATD +F  K+      +  H +  KP + 
Sbjct: 506  LDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQE---QGTHPKFQKPKQL 562

Query: 584  KFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY------- 636
            K +A F ++HYAG V Y    WL KN D LN+ +  +  +SS++ ++ L+++        
Sbjct: 563  KDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLD 622

Query: 637  ---MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693
                 +++A+P   K RK    F+TV  L+KE L KLM  L++T P+FVRCI PN  K  
Sbjct: 623  QVAGMSETALPGAFKTRK--GMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKA 680

Query: 694  GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753
            G LDP+LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P + PK  F+  ++A
Sbjct: 681  GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQA 739

Query: 754  AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813
               ++ +LE+D   YR G +KVFF+AG L  LE  RD +++ V   FQA  +G L R  F
Sbjct: 740  CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAF 799

Query: 814  QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873
             K  ++  A+ ++Q N  A++ ++NW W RLF K+KPL++ S   EE+   +EE  ++++
Sbjct: 800  AKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVRE 859

Query: 874  ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933
                +E +  E++  Q  L  EK  L  QLQAE E  A  EE    L   K +LE    +
Sbjct: 860  KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD 919

Query: 934  LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993
            L  RVEEEEE    L A  +K++    EL++++++ E+   K + EK TTE K+K L EE
Sbjct: 920  LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979

Query: 994  VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053
               L +   KL +  K++++   +   +L  EEEK  SL+K   K E  + +LE  L +E
Sbjct: 980  QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039

Query: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113
             K R   E+   KLEG+     + +  L++    L  +L KKE EL    ++VE E    
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099

Query: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173
                K ++EL++QI +L+E LE+ER +R K E+++ DL ++L  L   LE+   S+ AQ 
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159

Query: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233
            E+  K+E +   L + +EE     E     ++++H+ ++ EL  Q+E  ++VK  LEK K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219

Query: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293
              L+ E  +L   V+ + + K ++E      E +L E   K ++  ++  +LA + TKL 
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279

Query: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353
             E       L + ++  ++L+++ S    Q++D +  L++E + + +L+  L++ + + +
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
              REQ EEE+E K  L + ++ ++A++   + K E++V    E  E+ K++L   L+  +
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV-GCLETAEEVKRKLQKDLEGLS 1398

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
            +      A    LE+ + +LQ EL D L DL   R +A  L++KQ +  + LA+ K    
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458

Query: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533
            +     D ++ E +   T+ L L    EE++  +  L R NK  + E+ +L +   +  K
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518

Query: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593
            ++ E+EK K+ +E++  E++  LEE E  L+  E   L  ++ L   KA+ ER L  +DE
Sbjct: 1519 SVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE 1578

Query: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653
            + E  +++    +  +++ L+ E K R      +KK+E DL ++E  +  AN+   EA K
Sbjct: 1579 QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIK 1638

Query: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713
             L +LQ Q+KD   +LDD+     ++  Q    E++   +++E+  L+      ER +R 
Sbjct: 1639 QLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 1698

Query: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1773
            +++E  E  + I     +    L +K++LEA +A++++E EE     +   ++ KKA ++
Sbjct: 1699 AQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQ 1758

Query: 1774 AANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRE 1833
               ++ +L  ++      E  R+ +E+   +L+ +L E E       +  I  LE+++ +
Sbjct: 1759 IDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQ 1818

Query: 1834 LEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQ 1893
            LE +L+ E +    A +  RR E+ +K++  Q +++++N  + + Q DK   +++  K+Q
Sbjct: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878

Query: 1894 VEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
            +E AE +A +  +  +K Q EL +  E A+    +V+ LK K R
Sbjct: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922



 Score =  218 bits (555), Expect = 5e-56
 Identities = 215/973 (22%), Positives = 446/973 (45%), Gaps = 73/973 (7%)

Query: 851  LVKSSEVGEEVAGLKEE----CAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAE 906
            L +  E  + +A LK +       L++ L + E QR+EL+  +  L  +  DL  Q+   
Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067

Query: 907  QETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEI 966
            Q  +A ++ Q   L K + +L+A +     RVEEE    +    + R+LE +  EL++++
Sbjct: 1068 QAQIAELKMQ---LAKKEEELQAALA----RVEEEAAQKNMALKKIRELESQISELQEDL 1120

Query: 967  DDLETMLVKSEKEKRTTEHKVKNLTEEVE-FLNEDISKLNRAAKVVQEAH--QQTLDDLH 1023
            +       K+EK+KR    +++ L  E+E  L+   ++    +K  QE +  ++TL++  
Sbjct: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180

Query: 1024 MEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLES 1083
               E  + + +   K  Q V+EL   LEQ ++ + N E+    LE         ++ L  
Sbjct: 1181 KTHE--AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238

Query: 1084 SQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAK 1143
             +     + +K E +L ++  K    + +  +L   V +LQ ++ ++   L    +  +K
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298

Query: 1144 MERERADLTQDLADLNERLEEVGGSSLA---QLEITKKQETKFQKLHRDMEEATLHFETT 1200
            + ++ + L   L D  E L+E     L+   +L+  + ++  F++   + EEA  + E  
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358

Query: 1201 SASLKKRHADSLAELE---GQVENLQQVKQKLEKD---------------------KSDL 1236
             A+L  + AD   ++E   G +E  ++VK+KL+KD                     K+ L
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418

Query: 1237 QLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSES 1296
            Q E+DDLL  ++   ++  N EK    +++ L E      K  +  +   A+  +  +++
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478

Query: 1297 GEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLR 1356
                R LEE      +L R    F  ++EDL    +   KS   L  + +  ++  + ++
Sbjct: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538

Query: 1357 EQYEE-EQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEA 1415
             Q EE E E++A     L ++   +   + ++E ++  R E  E+ KK+L  +++E    
Sbjct: 1539 TQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597

Query: 1416 MGVANARNASLERARHQLQLELGDA---LSDLGKVRSAAAR----LDQKQLQSGKALADW 1468
            +     + +    AR +L+++L D    +    K R  A +    L  +     + L D 
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657

Query: 1469 KQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISN-LTNQ 1527
            +   EE  A    ++K+++++  E+++L    +E +   E  +R+ +  ++E+++ + N 
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELADEIANS 1713

Query: 1528 VREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELE 1585
              +G   L E    K+ +E    +++  LEE +G  E   +  K  + Q++ +     LE
Sbjct: 1714 SGKGALALEE----KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE 1769

Query: 1586 RKLSEKDE----EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1641
            R  ++K+E    ++E   ++ +  +  ++ ++ S+ K+ I        +E  + ++E QL
Sbjct: 1770 RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA------LEAKIAQLEEQL 1823

Query: 1642 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLR 1701
                ++   A K + + + ++KD+ +Q+DD  +     K+Q   A  R   L+ +LE+  
Sbjct: 1824 DNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAE 1883

Query: 1702 SLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQ 1761
               ++    RR  + EL +ATE  +    + +SL ++ ++ +      ++ A +   +  
Sbjct: 1884 EEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGS 1943

Query: 1762 NAEEKAKKAAIEA 1774
            + E   K    EA
Sbjct: 1944 DEEVDGKADGAEA 1956



 Score =  180 bits (456), Expect = 1e-44
 Identities = 191/892 (21%), Positives = 378/892 (42%), Gaps = 97/892 (10%)

Query: 1090 EELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERA 1149
            EE+  KE EL ++  K    +  + +++    +L  +   L+E+L+AE    A+ E  RA
Sbjct: 845  EEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRA 904

Query: 1150 DLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHA 1209
             LT       + LEE+     A++E   ++E + Q L  +               KK+  
Sbjct: 905  RLTAK----KQELEEICHDLEARVE---EEEERCQHLQAE---------------KKKMQ 942

Query: 1210 DSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEER-- 1267
             ++ ELE Q+E  +  +QKL+ +K   +                     KL  L EE+  
Sbjct: 943  QNIQELEEQLEEEESARQKLQLEKVTTEA--------------------KLKKLEEEQII 982

Query: 1268 LHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDL 1327
            L +   KL K  +L  D  A          EF   L E+E     L++ K+     I DL
Sbjct: 983  LEDQNCKLAKEKKLLEDRIA----------EFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032

Query: 1328 RGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEM------V 1381
              +L +E K +  L    +K + D   L +Q  E Q   AEL   L+K   E+      V
Sbjct: 1033 EERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARV 1092

Query: 1382 QWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDAL 1441
            +     +N  +++  +LE    EL   L+    +   A  +   L      L+ EL D L
Sbjct: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTL 1152

Query: 1442 SDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYE 1501
                  +   ++ +Q+     K L +  + HE    + +  QK  QA+     +L    E
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ--IQEMRQKHSQAVE----ELAEQLE 1206

Query: 1502 ESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEG 1561
            ++   +  L +  + L+ E   L N+V+   +   + E  +K +E +  E+QV   E E 
Sbjct: 1207 QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER 1266

Query: 1562 ALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRI 1621
                   K+   Q+EL      L +  S+  +  ++F   +    D+ Q  L  E + ++
Sbjct: 1267 VRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT-QELLQEENRQKL 1325

Query: 1622 EVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDST-------- 1673
             ++   K++E++ N    QL           K +  L  Q+ D++ +++DS         
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385

Query: 1674 ---QLNSDLK-------EQVAV---AERRNSLLQSELEDLR-SLQEQTERGRRLSE---- 1715
               +L  DL+       E+VA     E+  + LQ EL+DL   L  Q +    L +    
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445

Query: 1716 -EELLEATERINLFYTQNTSLL-SQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1773
             ++LL   + I+  Y +      ++ ++ E     + +  EE +++    E   K+   E
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505

Query: 1774 AANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRE 1833
              +L         ++  LE+++  +EQ + +++ +L E E   L  +     +LE  ++ 
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED-ELQATEDAKLRLEVNLQA 1564

Query: 1834 LEGELEGEIR-RSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQ 1892
            ++ + E +++ R  +++   ++L R ++E+  + E+++K  S       KL++ +++ + 
Sbjct: 1565 MKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEA 1624

Query: 1893 QVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQ 1944
             ++ A    ++ + + +K Q ++ +     +   +   ++  +A+E  KK++
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLK 1676



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 79/336 (23%), Positives = 159/336 (47%), Gaps = 27/336 (8%)

Query: 1613 LDSEAKSRIEVTRLKKKM----EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQ 1668
            L ++ K  ++V+R +++M    EE +   E QL+  NR     T     LQ Q+   ++Q
Sbjct: 830  LFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMET-----LQSQLMAEKLQ 884

Query: 1669 LDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLF 1728
            L +  Q  ++L    A AE   + L ++ ++L  +    E   R+ EEE     ER    
Sbjct: 885  LQEQLQAETEL---CAEAEELRARLTAKKQELEEICHDLEA--RVEEEE-----ERCQ-- 932

Query: 1729 YTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTI 1788
                  L ++KKK++ ++  ++++ EE     Q  + +      +   L EE    +D  
Sbjct: 933  -----HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987

Query: 1789 AHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEA 1848
              L + ++ +E  I +    L E E+ +     K   K E+ + +LE  L  E ++  E 
Sbjct: 988  CKLAKEKKLLEDRIAEFTTNLTEEEEKS-KSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046

Query: 1849 QRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKY 1908
            ++  R+LE    +L+ Q  E +  ++ ++ Q+ K + ++Q    +VE    Q N  L K 
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKI 1106

Query: 1909 KKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQ 1944
            ++ + +++E++E  E   +  NK + + R+ G++++
Sbjct: 1107 RELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 33/178 (18%)

Query: 1769 KAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLE 1828
            K  ++ +   EE+  K++ +  +   +   E  +T++     E  Q  LM  + Q+Q+  
Sbjct: 835  KPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEM-----ETLQSQLMAEKLQLQEQL 889

Query: 1829 SRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQ 1888
                EL  E E E+R    A++  + LE    +L  + EE+++    +Q +  K+Q  +Q
Sbjct: 890  QAETELCAEAE-ELRARLTAKK--QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946

Query: 1889 NYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQEE 1946
                                     EL E  E  E A  ++   K+      KK++EE
Sbjct: 947  -------------------------ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 1155 bits (2989), Expect = 0.0
 Identities = 682/1909 (35%), Positives = 1077/1909 (56%), Gaps = 37/1909 (1%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            ++  W+P   + +  A ++   ++   +     G  L +  D+IQ+MNPP+F   EDMA 
Sbjct: 53   RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 113  LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228
            H++AV   A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK+ G   
Sbjct: 173  HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPG 232

Query: 229  -LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
             LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I
Sbjct: 233  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292

Query: 288  FQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQA 347
             Q   E ++HIFYQ+L G  E     L+    S + F + G  +     + E    T ++
Sbjct: 293  RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELFQETLES 351

Query: 348  MDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSEL 407
            + +LGF  +E     ++  A++ FGN+  K++   +Q        A K   L+G+  ++ 
Sbjct: 352  LRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDF 411

Query: 408  VKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQ- 466
             + L+ PRIKVG +YV + QT EQ   A+ AL+K+ YER+F+WLV R+NRALD +  RQ 
Sbjct: 412  SRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQG 470

Query: 467  -FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGF 525
              F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN  MFVLEQEEY++E I W  + F
Sbjct: 471  ASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDF 530

Query: 526  GLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDK 582
            GLDLQ CIDLIE+P    G+L++L+EEC FPKATD +F  K+     G   H +  +P  
Sbjct: 531  GLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---HPKFQRPRH 587

Query: 583  KKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF--------- 633
             + +A F ++HYAG V Y  + WL KN D LN+ V A+  +S++RL A ++         
Sbjct: 588  LRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGL 647

Query: 634  ENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693
            E   S     P G  +R     F+TV  L+KE+L++LM  L +T P FVRCI PN  K  
Sbjct: 648  EQVSSLGDGPPGGRPRR---GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRA 704

Query: 694  GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753
            G L+P LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P   PK  F+  ++A
Sbjct: 705  GKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA 763

Query: 754  AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813
             E+++ +LE+D   YR G +K+FF+AG L QLE  RD +++ +   FQA A+G L R  F
Sbjct: 764  CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823

Query: 814  QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873
            QK  +++ AL ++Q N  A++ +++W W RLF K+KPL++ +   E +    +E  ++Q+
Sbjct: 824  QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883

Query: 874  ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933
              ++S  +  EL+ +   L +E+  L  QL+AE E  A  EE    L   K +LE  V E
Sbjct: 884  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943

Query: 934  LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993
            L  RV EEEE + ++    ++L+    EL+  ++  E    K + EK TTE K+K   E+
Sbjct: 944  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003

Query: 994  VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053
            +  L +  SKL++  K++++   +       EEEK+ SL+K  LK E  + ++E  L +E
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113
             K R   E+   +L+G     +E M   +     L  +L +KE EL    ++ E+E G  
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123

Query: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173
            AQL K+++E Q  + + +E LE+ER  R K E++R DL ++L  L   LE+   S+ AQ 
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183

Query: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233
            E+  K+E +  +L + +EE T   E     L++RH  +L EL  Q+E  ++ K   EK +
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293
              L+ EV +L   +  +  A+   E+     E +L E   +     +   + A +  +  
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353
            +E       L E E+   +LS+E S+   Q+ D +  L++ET+++ AL   ++  + +  
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             LREQ EEE   +    R L    A++ +WR + E       E  E+A++  A   +   
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALT 1422

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQK-- 1471
            + +         LER R +LQ EL DA  DL + R   + L++KQ +  + LA+ K    
Sbjct: 1423 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482

Query: 1472 ---HEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQV 1528
                E  +A  +  ++E +ALS     L    EE    +E L R+N+ L+ E+  L +  
Sbjct: 1483 RAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNRALRAELEALLSSK 1537

Query: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588
             +  K++ E+E+  ++ E+   +++  + E E  L   E   L  ++ +   K + ER L
Sbjct: 1538 DDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDL 1597

Query: 1589 SEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQV 1648
              +DE  E  RR+    +   +   D E K R      +KK+E +L E++ Q++ A +  
Sbjct: 1598 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGK 1657

Query: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTE 1708
             EA K L ++Q Q+K+L  +++++     ++  Q   +E+R   L++E+  L+     ++
Sbjct: 1658 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASD 1717

Query: 1709 RGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAK 1768
            R RR ++++  E  + +        ++L +K++LE  + ++++E EE     +   ++ +
Sbjct: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYR 1777

Query: 1769 KAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLE 1828
            K  ++  +L+ EL  ++   A  E  R+ +E+ I +L+ RL E +  A    +  I  LE
Sbjct: 1778 KLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALE 1837

Query: 1829 SRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQ 1888
            S++ + E +LE E R    + +  RR E+ +KE+  Q EE+++   +++ Q++K  L+V+
Sbjct: 1838 SKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVK 1897

Query: 1889 NYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
              K+Q+E AE +A++  +  ++ Q EL +V E AE    +V  L+ + R
Sbjct: 1898 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946



 Score =  189 bits (479), Expect = 3e-47
 Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)

Query: 784  QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
            QLE +  E   K F    L       KL   K +K+LE+R A    Q        VK+  
Sbjct: 987  QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1043

Query: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
             +RL ++         + +E  G +E    L+K   + + +  EL+ + V   Q   +L 
Sbjct: 1044 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1099

Query: 901  LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
             QL  ++E L     + E        L+KS  + +A + E  E +E E    ++   + R
Sbjct: 1100 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159

Query: 954  KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
             L +E   L+ E++D    L  +  ++     + + +TE  + L E+      A + +++
Sbjct: 1160 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1216

Query: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
             H Q L +L  + E+      +  K  L LE +V EL   L   + AR   E+   +LE 
Sbjct: 1217 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1276

Query: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
             L+  +    + E ++   AE+L++ + EL  ++  +   +    +L K +   + Q+ D
Sbjct: 1277 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1336

Query: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186
             +E L+ E  TRAK+    R RA +  + A L E+LEE   +        +  + +  + 
Sbjct: 1337 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1393

Query: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246
             R  EE     E    + ++   ++ A  +   E  + V  +LE+ +  LQ E+DD    
Sbjct: 1394 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1452

Query: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
            +EQ  +  +  EK    +++ L E  A + +  +      A+  +  + +    R LEE+
Sbjct: 1453 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1512

Query: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366
            +    +L R+      ++E L    +   KS   L  A + A++  + LR Q  E ++  
Sbjct: 1513 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572

Query: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426
                    ++   +   + ++E ++  R E  E+ +++LA +L++A         +    
Sbjct: 1573 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632

Query: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479
              AR +L+ EL +  + +         A  +L + Q Q     + + + +   EE  +  
Sbjct: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1692

Query: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
              S+K ++ L  E+L+L    +E +   +  RR+    Q++   + ++V  G  +   + 
Sbjct: 1693 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1745

Query: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597
            + K+ +E    +++  LEE +   E   +  + L  Q+E L  +   ER  S K    E+
Sbjct: 1746 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1802

Query: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654
             R++ +  I  L+  L   D+ A++R ++T     +E  L + E QL    R+   + K 
Sbjct: 1803 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1860

Query: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714
            + + + ++K++ +Q+++  ++   L++Q+     R   L+ +LE+      + + GRR  
Sbjct: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920

Query: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765
            + EL + TE       + T+L ++ ++          R     EE V   + AEE
Sbjct: 1921 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975



 Score =  174 bits (440), Expect = 1e-42
 Identities = 223/977 (22%), Positives = 403/977 (41%), Gaps = 106/977 (10%)

Query: 1022 LHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENL 1081
            L    ++L  + +   +  ++V EL+G + Q        E E  +L   L+   E     
Sbjct: 871  LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARLAEQLRAEAELCAEA 923

Query: 1082 ESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER--- 1138
            E ++  LA   ++ EL +S++ ++V  E+    Q+Q   K LQ  I++L+  LEAE    
Sbjct: 924  EETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 983

Query: 1139 --------TTRAKMERERADL----------TQDLADLNERLEEVGGSSLAQLEITK--- 1177
                    TT AKM++   DL          +++   L +RL E    +  + E  K   
Sbjct: 984  QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1043

Query: 1178 KQETKFQKLHRDMEEATLHFETTSASL---KKRHADSLAELEGQVENLQQVKQKLEKDKS 1234
            K   K++    DME+     E     L   K+R     +EL+ Q+   QQ  ++L     
Sbjct: 1044 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1103

Query: 1235 DLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWS 1294
              + E+   L R E    A+A   K     +  L EA   L+           Q+  L  
Sbjct: 1104 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1163

Query: 1295 ESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL-QKAQRDCD 1353
            E       LE+     N     +S   +++ +L+  LE+ET+   A    L Q+  +   
Sbjct: 1164 ELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALG 1223

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             L EQ E+ +  K    +T   + AE+ + R +  +    R E  E  ++ L ++LQE  
Sbjct: 1224 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG-EQRRRRLELQLQEVQ 1282

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
               G      A       + Q EL +    L +  S   RL ++   +   L D ++  +
Sbjct: 1283 GRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQ 1342

Query: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533
            E      A    V+A+  E   L+   EE    +E   RE +  Q ++S    +  E   
Sbjct: 1343 EETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAG 1402

Query: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593
             L   E+ ++    E   +   L E    ++R E      Q EL +A  +LE++      
Sbjct: 1403 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-----R 1457

Query: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653
            ++ +   K+Q   D L   L  E  + +     +++ E +  E E +     R + E  +
Sbjct: 1458 QLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQE 1514

Query: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713
            +  +L+ Q + L+ +L+       D+ + V   ER   + +    DLR+  + TE     
Sbjct: 1515 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA--QVTEL---- 1568

Query: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA-EEKAKKAA- 1771
             E+EL  A +               K +LE  V  ++ + E  +Q    A EE+ ++ A 
Sbjct: 1569 -EDELTAAEDA--------------KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1613

Query: 1772 -IEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
             +  A +  + ++KQ T+A     R+ +E  + +L+ ++A A Q     + KQ++K++++
Sbjct: 1614 QLRDAEVERDEERKQRTLA--VAARKKLEGELEELKAQMASAGQ-GKEEAVKQLRKMQAQ 1670

Query: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKV--- 1887
            ++EL  E+E E R S E             E+  Q  E +K L  ++ ++ +LQ ++   
Sbjct: 1671 MKELWREVE-ETRTSRE-------------EIFSQNRESEKRLKGLEAEVLRLQEELAAS 1716

Query: 1888 -----QNYKQQVEVAETQANQYLSK-----YKKQ--------QHELNEVKERAEVAESQV 1929
                 Q  + + E+A+  AN  LSK      K+Q        + EL E +  +E+   + 
Sbjct: 1717 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1776

Query: 1930 NKLKIKAREFGKKVQEE 1946
             KL ++      ++  E
Sbjct: 1777 RKLLLQVESLTTELSAE 1793


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 1152 bits (2981), Expect = 0.0
 Identities = 682/1917 (35%), Positives = 1077/1917 (56%), Gaps = 45/1917 (2%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            ++  W+P   + +  A ++   ++   +     G  L +  D+IQ+MNPP+F   EDMA 
Sbjct: 53   RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 113  LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228
            H++AV   A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK+ G   
Sbjct: 173  HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA 232

Query: 229  ---------LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIY 279
                     LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ Y
Sbjct: 233  SVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 292

Query: 280  LLEKSRVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAE 339
            LLEKSR I Q   E ++HIFYQ+L G  E     L+    S + F + G  +     + E
Sbjct: 293  LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERE 351

Query: 340  ELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFL 399
                T +++ +LGF  +E     ++  A++ FGN+  K++   +Q        A K   L
Sbjct: 352  LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411

Query: 400  MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
            +G+  ++  + L+ PRIKVG +YV + QT EQ   A+ AL+K+ YER+F+WLV R+NRAL
Sbjct: 412  LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471

Query: 460  DAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKES 517
            D +  RQ   F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN  MFVLEQEEY++E 
Sbjct: 472  D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530

Query: 518  IEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVH 574
            I W  + FGLDLQ CIDLIE+P    G+L++L+EEC FPKATD +F  K+     G   H
Sbjct: 531  IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---H 587

Query: 575  LQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF- 633
             +  +P   + +A F ++HYAG V Y  + WL KN D LN+ V A+  +S++RL A ++ 
Sbjct: 588  PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647

Query: 634  --------ENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCI 685
                    E   S     P G  +R     F+TV  L+KE+L++LM  L +T P FVRCI
Sbjct: 648  DVEGIVGLEQVSSLGDGPPGGRPRR---GMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 704

Query: 686  NPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKS 745
             PN  K  G L+P LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P   PK 
Sbjct: 705  VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 764

Query: 746  KFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQ 805
             F+  ++A E+++ +LE+D   YR G +K+FF+AG L QLE  RD +++ +   FQA A+
Sbjct: 765  -FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823

Query: 806  GKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLK 865
            G L R  FQK  +++ AL ++Q N  A++ +++W W RLF K+KPL++ +   E +    
Sbjct: 824  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883

Query: 866  EECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKI 925
            +E  ++Q+  ++S  +  EL+ +   L +E+  L  QL+AE E  A  EE    L   K 
Sbjct: 884  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943

Query: 926  QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH 985
            +LE  V EL  RV EEEE + ++    ++L+    EL+  ++  E    K + EK TTE 
Sbjct: 944  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003

Query: 986  KVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDE 1045
            K+K   E++  L +  SKL++  K++++   +       EEEK+ SL+K  LK E  + +
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063

Query: 1046 LEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSK 1105
            +E  L +E K R   E+   +L+G     +E M   +     L  +L +KE EL    ++
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123

Query: 1106 VENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEV 1165
             E+E G  AQL K+++E Q  + + +E LE+ER  R K E++R DL ++L  L   LE+ 
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183

Query: 1166 GGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQV 1225
              S+ AQ E+  K+E +  +L + +EE T   E     L++RH  +L EL  Q+E  ++ 
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243

Query: 1226 KQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDL 1285
            K   EK +  L+ EV +L   +  +  A+   E+     E +L E   +     +   + 
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303

Query: 1286 AAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL 1345
            A +  +  +E       L E E+   +LS+E S+   Q+ D +  L++ET+++ AL   +
Sbjct: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363

Query: 1346 QKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKEL 1405
            +  + +   LREQ EEE   +    R L    A++ +WR + E       E  E+A++  
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRA 1422

Query: 1406 AIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKAL 1465
            A   +   + +         LER R +LQ EL DA  DL + R   + L++KQ +  + L
Sbjct: 1423 AREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1482

Query: 1466 ADWKQK-----HEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEE 1520
            A+ K        E  +A  +  ++E +ALS     L    EE    +E L R+N+ L+ E
Sbjct: 1483 AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNRALRAE 1537

Query: 1521 ISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEA 1580
            +  L +   +  K++ E+E+  ++ E+   +++  + E E  L   E   L  ++ +   
Sbjct: 1538 LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1597

Query: 1581 KAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ 1640
            K + ER L  +DE  E  RR+    +   +   D E K R      +KK+E +L E++ Q
Sbjct: 1598 KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQ 1657

Query: 1641 LSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDL 1700
            ++ A +   EA K L ++Q Q+K+L  +++++     ++  Q   +E+R   L++E+  L
Sbjct: 1658 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRL 1717

Query: 1701 RSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQEC 1760
            +     ++R RR ++++  E  + +        ++L +K++LE  + ++++E EE     
Sbjct: 1718 QEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS 1777

Query: 1761 QNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGS 1820
            +   ++ +K  ++  +L+ EL  ++   A  E  R+ +E+ I +L+ RL E +  A    
Sbjct: 1778 ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARH 1837

Query: 1821 RKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQM 1880
            +  I  LES++ + E +LE E R    + +  RR E+ +KE+  Q EE+++   +++ Q+
Sbjct: 1838 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQL 1897

Query: 1881 DKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
            +K  L+V+  K+Q+E AE +A++  +  ++ Q EL +V E AE    +V  L+ + R
Sbjct: 1898 EKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954



 Score =  189 bits (479), Expect = 3e-47
 Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)

Query: 784  QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
            QLE +  E   K F    L       KL   K +K+LE+R A    Q        VK+  
Sbjct: 995  QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1051

Query: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
             +RL ++         + +E  G +E    L+K   + + +  EL+ + V   Q   +L 
Sbjct: 1052 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1107

Query: 901  LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
             QL  ++E L     + E        L+KS  + +A + E  E +E E    ++   + R
Sbjct: 1108 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167

Query: 954  KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
             L +E   L+ E++D    L  +  ++     + + +TE  + L E+      A + +++
Sbjct: 1168 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1224

Query: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
             H Q L +L  + E+      +  K  L LE +V EL   L   + AR   E+   +LE 
Sbjct: 1225 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1284

Query: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
             L+  +    + E ++   AE+L++ + EL  ++  +   +    +L K +   + Q+ D
Sbjct: 1285 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1344

Query: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186
             +E L+ E  TRAK+    R RA +  + A L E+LEE   +        +  + +  + 
Sbjct: 1345 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1401

Query: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246
             R  EE     E    + ++   ++ A  +   E  + V  +LE+ +  LQ E+DD    
Sbjct: 1402 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1460

Query: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
            +EQ  +  +  EK    +++ L E  A + +  +      A+  +  + +    R LEE+
Sbjct: 1461 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1520

Query: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366
            +    +L R+      ++E L    +   KS   L  A + A++  + LR Q  E ++  
Sbjct: 1521 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1580

Query: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426
                    ++   +   + ++E ++  R E  E+ +++LA +L++A         +    
Sbjct: 1581 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640

Query: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479
              AR +L+ EL +  + +         A  +L + Q Q     + + + +   EE  +  
Sbjct: 1641 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1700

Query: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
              S+K ++ L  E+L+L    +E +   +  RR+    Q++   + ++V  G  +   + 
Sbjct: 1701 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1753

Query: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597
            + K+ +E    +++  LEE +   E   +  + L  Q+E L  +   ER  S K    E+
Sbjct: 1754 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1810

Query: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654
             R++ +  I  L+  L   D+ A++R ++T     +E  L + E QL    R+   + K 
Sbjct: 1811 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1868

Query: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714
            + + + ++K++ +Q+++  ++   L++Q+     R   L+ +LE+      + + GRR  
Sbjct: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928

Query: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765
            + EL + TE       + T+L ++ ++          R     EE V   + AEE
Sbjct: 1929 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983



 Score =  174 bits (440), Expect = 1e-42
 Identities = 223/977 (22%), Positives = 403/977 (41%), Gaps = 106/977 (10%)

Query: 1022 LHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENL 1081
            L    ++L  + +   +  ++V EL+G + Q        E E  +L   L+   E     
Sbjct: 879  LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARLAEQLRAEAELCAEA 931

Query: 1082 ESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER--- 1138
            E ++  LA   ++ EL +S++ ++V  E+    Q+Q   K LQ  I++L+  LEAE    
Sbjct: 932  EETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 991

Query: 1139 --------TTRAKMERERADL----------TQDLADLNERLEEVGGSSLAQLEITK--- 1177
                    TT AKM++   DL          +++   L +RL E    +  + E  K   
Sbjct: 992  QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1051

Query: 1178 KQETKFQKLHRDMEEATLHFETTSASL---KKRHADSLAELEGQVENLQQVKQKLEKDKS 1234
            K   K++    DME+     E     L   K+R     +EL+ Q+   QQ  ++L     
Sbjct: 1052 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1111

Query: 1235 DLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWS 1294
              + E+   L R E    A+A   K     +  L EA   L+           Q+  L  
Sbjct: 1112 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1171

Query: 1295 ESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL-QKAQRDCD 1353
            E       LE+     N     +S   +++ +L+  LE+ET+   A    L Q+  +   
Sbjct: 1172 ELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALG 1231

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             L EQ E+ +  K    +T   + AE+ + R +  +    R E  E  ++ L ++LQE  
Sbjct: 1232 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG-EQRRRRLELQLQEVQ 1290

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
               G      A       + Q EL +    L +  S   RL ++   +   L D ++  +
Sbjct: 1291 GRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQ 1350

Query: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533
            E      A    V+A+  E   L+   EE    +E   RE +  Q ++S    +  E   
Sbjct: 1351 EETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAG 1410

Query: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593
             L   E+ ++    E   +   L E    ++R E      Q EL +A  +LE++      
Sbjct: 1411 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-----R 1465

Query: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653
            ++ +   K+Q   D L   L  E  + +     +++ E +  E E +     R + E  +
Sbjct: 1466 QLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQE 1522

Query: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713
            +  +L+ Q + L+ +L+       D+ + V   ER   + +    DLR+  + TE     
Sbjct: 1523 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA--QVTEL---- 1576

Query: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA-EEKAKKAA- 1771
             E+EL  A +               K +LE  V  ++ + E  +Q    A EE+ ++ A 
Sbjct: 1577 -EDELTAAEDA--------------KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1621

Query: 1772 -IEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
             +  A +  + ++KQ T+A     R+ +E  + +L+ ++A A Q     + KQ++K++++
Sbjct: 1622 QLRDAEVERDEERKQRTLA--VAARKKLEGELEELKAQMASAGQ-GKEEAVKQLRKMQAQ 1678

Query: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKV--- 1887
            ++EL  E+E E R S E             E+  Q  E +K L  ++ ++ +LQ ++   
Sbjct: 1679 MKELWREVE-ETRTSRE-------------EIFSQNRESEKRLKGLEAEVLRLQEELAAS 1724

Query: 1888 -----QNYKQQVEVAETQANQYLSK-----YKKQ--------QHELNEVKERAEVAESQV 1929
                 Q  + + E+A+  AN  LSK      K+Q        + EL E +  +E+   + 
Sbjct: 1725 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1784

Query: 1930 NKLKIKAREFGKKVQEE 1946
             KL ++      ++  E
Sbjct: 1785 RKLLLQVESLTTELSAE 1801


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 1141 bits (2952), Expect = 0.0
 Identities = 681/1947 (34%), Positives = 1081/1947 (55%), Gaps = 72/1947 (3%)

Query: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
            ++  W+P   + +  A ++   ++   +     G  L +  D+IQ+MNPP+F   EDMA 
Sbjct: 53   RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112

Query: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
            LT LNEASVLH L+ RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 113  LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172

Query: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228
            H++AV   A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK+ G   
Sbjct: 173  HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA 232

Query: 229  ---------LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIY 279
                     LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ Y
Sbjct: 233  SVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 292

Query: 280  LLEKSRVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAE 339
            LLEKSR I Q   E ++HIFYQ+L G  E     L+    S + F + G  +     + E
Sbjct: 293  LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERE 351

Query: 340  ELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFL 399
                T +++ +LGF  +E     ++  A++ FGN+  K++   +Q        A K   L
Sbjct: 352  LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411

Query: 400  MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
            +G+  ++  + L+ PRIKVG +YV + QT EQ   A+ AL+K+ YER+F+WLV R+NRAL
Sbjct: 412  LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471

Query: 460  DAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKES 517
            D +  RQ   F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN  MFVLEQEEY++E 
Sbjct: 472  D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530

Query: 518  IEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVH 574
            I W  + FGLDLQ CIDLIE+P    G+L++L+EEC FPKATD +F  K+     G   H
Sbjct: 531  IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---H 587

Query: 575  LQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFE 634
             +  +P   + +A F ++HYAG V Y  + WL KN D LN+ V A+  +S++RL A +++
Sbjct: 588  PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647

Query: 635  N---------YMSTDSAIPFGEKKRKKGA------------------------------S 655
            +         ++ +    P G  +R   A                               
Sbjct: 648  DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707

Query: 656  FQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTR 715
            F+TV  L+KE+L++LM  L +T P FVRCI PN  K  G L+P LVL QLRCNGVLEG R
Sbjct: 708  FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767

Query: 716  ICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKV 775
            ICR+GFPNR+ + +F+QRY IL P   PK  F+  ++A E+++ +LE+D   YR G +K+
Sbjct: 768  ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826

Query: 776  FFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMA 835
            FF+AG L QLE  RD +++ +   FQA A+G L R  FQK  +++ AL ++Q N  A++ 
Sbjct: 827  FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886

Query: 836  VKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQE 895
            +++W W RLF K+KPL++ +   E +    +E  ++Q+  ++S  +  EL+ +   L +E
Sbjct: 887  LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946

Query: 896  KNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKL 955
            +  L  QL+AE E  A  EE    L   K +LE  V EL  RV EEEE + ++    ++L
Sbjct: 947  RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006

Query: 956  EDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAH 1015
            +    EL+  ++  E    K + EK TTE K+K   E++  L +  SKL++  K++++  
Sbjct: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066

Query: 1016 QQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNR 1075
             +       EEEK+ SL+K  LK E  + ++E  L +E K R   E+   +L+G     +
Sbjct: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126

Query: 1076 ESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLE 1135
            E M   +     L  +L +KE EL    ++ E+E G  AQL K+++E Q  + + +E LE
Sbjct: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186

Query: 1136 AERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATL 1195
            +ER  R K E++R DL ++L  L   LE+   S+ AQ E+  K+E +  +L + +EE T 
Sbjct: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246

Query: 1196 HFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKA 1255
              E     L++RH  +L EL  Q+E  ++ K   EK +  L+ EV +L   +  +  A+ 
Sbjct: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306

Query: 1256 NAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR 1315
              E+     E +L E   +     +   + A +  +  +E       L E E+   +LS+
Sbjct: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366

Query: 1316 EKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSK 1375
            E S+   Q+ D +  L++ET+++ AL   ++  + +   LREQ EEE   +    R L  
Sbjct: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426

Query: 1376 VNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435
              A++ +WR + E       E  E+A++  A   +   + +         LER R +LQ 
Sbjct: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485

Query: 1436 ELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQK-----HEESQALLDASQKEVQALS 1490
            EL DA  DL + R   + L++KQ +  + LA+ K        E  +A  +  ++E +ALS
Sbjct: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545

Query: 1491 TELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKT 1550
                 L    EE    +E L R+N+ L+ E+  L +   +  K++ E+E+  ++ E+   
Sbjct: 1546 -----LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1600

Query: 1551 EVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQ 1610
            +++  + E E  L   E   L  ++ +   K + ER L  +DE  E  RR+    +   +
Sbjct: 1601 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1660

Query: 1611 SSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLD 1670
               D E K R      +KK+E +L E++ Q++ A +   EA K L ++Q Q+K+L  +++
Sbjct: 1661 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1720

Query: 1671 DSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYT 1730
            ++     ++  Q   +E+R   L++E+  L+     ++R RR ++++  E  + +     
Sbjct: 1721 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1780

Query: 1731 QNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAH 1790
               ++L +K++LE  + ++++E EE     +   ++ +K  ++  +L+ EL  ++   A 
Sbjct: 1781 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1840

Query: 1791 LERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQR 1850
             E  R+ +E+ I +L+ RL E +  A    +  I  LES++ + E +LE E R    + +
Sbjct: 1841 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 1900

Query: 1851 GARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKK 1910
              RR E+ +KE+  Q EE+++   +++ Q++K  L+V+  K+Q+E AE +A++  +  ++
Sbjct: 1901 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1960

Query: 1911 QQHELNEVKERAEVAESQVNKLKIKAR 1937
             Q EL +V E AE    +V  L+ + R
Sbjct: 1961 LQRELEDVTESAESMNREVTTLRNRLR 1987



 Score =  189 bits (479), Expect = 3e-47
 Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)

Query: 784  QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
            QLE +  E   K F    L       KL   K +K+LE+R A    Q        VK+  
Sbjct: 1028 QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1084

Query: 841  WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
             +RL ++         + +E  G +E    L+K   + + +  EL+ + V   Q   +L 
Sbjct: 1085 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1140

Query: 901  LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
             QL  ++E L     + E        L+KS  + +A + E  E +E E    ++   + R
Sbjct: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200

Query: 954  KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
             L +E   L+ E++D    L  +  ++     + + +TE  + L E+      A + +++
Sbjct: 1201 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257

Query: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
             H Q L +L  + E+      +  K  L LE +V EL   L   + AR   E+   +LE 
Sbjct: 1258 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1317

Query: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
             L+  +    + E ++   AE+L++ + EL  ++  +   +    +L K +   + Q+ D
Sbjct: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377

Query: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186
             +E L+ E  TRAK+    R RA +  + A L E+LEE   +        +  + +  + 
Sbjct: 1378 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1434

Query: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246
             R  EE     E    + ++   ++ A  +   E  + V  +LE+ +  LQ E+DD    
Sbjct: 1435 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1493

Query: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
            +EQ  +  +  EK    +++ L E  A + +  +      A+  +  + +    R LEE+
Sbjct: 1494 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1553

Query: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366
            +    +L R+      ++E L    +   KS   L  A + A++  + LR Q  E ++  
Sbjct: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613

Query: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426
                    ++   +   + ++E ++  R E  E+ +++LA +L++A         +    
Sbjct: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673

Query: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479
              AR +L+ EL +  + +         A  +L + Q Q     + + + +   EE  +  
Sbjct: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1733

Query: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
              S+K ++ L  E+L+L    +E +   +  RR+    Q++   + ++V  G  +   + 
Sbjct: 1734 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1786

Query: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597
            + K+ +E    +++  LEE +   E   +  + L  Q+E L  +   ER  S K    E+
Sbjct: 1787 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1843

Query: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654
             R++ +  I  L+  L   D+ A++R ++T     +E  L + E QL    R+   + K 
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1901

Query: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714
            + + + ++K++ +Q+++  ++   L++Q+     R   L+ +LE+      + + GRR  
Sbjct: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961

Query: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765
            + EL + TE       + T+L ++ ++          R     EE V   + AEE
Sbjct: 1962 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016



 Score =  174 bits (440), Expect = 1e-42
 Identities = 223/977 (22%), Positives = 403/977 (41%), Gaps = 106/977 (10%)

Query: 1022 LHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENL 1081
            L    ++L  + +   +  ++V EL+G + Q        E E  +L   L+   E     
Sbjct: 912  LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEERARLAEQLRAEAELCAEA 964

Query: 1082 ESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER--- 1138
            E ++  LA   ++ EL +S++ ++V  E+    Q+Q   K LQ  I++L+  LEAE    
Sbjct: 965  EETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 1024

Query: 1139 --------TTRAKMERERADL----------TQDLADLNERLEEVGGSSLAQLEITK--- 1177
                    TT AKM++   DL          +++   L +RL E    +  + E  K   
Sbjct: 1025 QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1084

Query: 1178 KQETKFQKLHRDMEEATLHFETTSASL---KKRHADSLAELEGQVENLQQVKQKLEKDKS 1234
            K   K++    DME+     E     L   K+R     +EL+ Q+   QQ  ++L     
Sbjct: 1085 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1144

Query: 1235 DLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWS 1294
              + E+   L R E    A+A   K     +  L EA   L+           Q+  L  
Sbjct: 1145 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1204

Query: 1295 ESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL-QKAQRDCD 1353
            E       LE+     N     +S   +++ +L+  LE+ET+   A    L Q+  +   
Sbjct: 1205 ELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALG 1264

Query: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             L EQ E+ +  K    +T   + AE+ + R +  +    R E  E  ++ L ++LQE  
Sbjct: 1265 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG-EQRRRRLELQLQEVQ 1323

Query: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
               G      A       + Q EL +    L +  S   RL ++   +   L D ++  +
Sbjct: 1324 GRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQ 1383

Query: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533
            E      A    V+A+  E   L+   EE    +E   RE +  Q ++S    +  E   
Sbjct: 1384 EETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAG 1443

Query: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593
             L   E+ ++    E   +   L E    ++R E      Q EL +A  +LE++      
Sbjct: 1444 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-----R 1498

Query: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653
            ++ +   K+Q   D L   L  E  + +     +++ E +  E E +     R + E  +
Sbjct: 1499 QLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQE 1555

Query: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713
            +  +L+ Q + L+ +L+       D+ + V   ER   + +    DLR+  + TE     
Sbjct: 1556 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRA--QVTEL---- 1609

Query: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA-EEKAKKAA- 1771
             E+EL  A +               K +LE  V  ++ + E  +Q    A EE+ ++ A 
Sbjct: 1610 -EDELTAAEDA--------------KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1654

Query: 1772 -IEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
             +  A +  + ++KQ T+A     R+ +E  + +L+ ++A A Q     + KQ++K++++
Sbjct: 1655 QLRDAEVERDEERKQRTLA--VAARKKLEGELEELKAQMASAGQ-GKEEAVKQLRKMQAQ 1711

Query: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKV--- 1887
            ++EL  E+E E R S E             E+  Q  E +K L  ++ ++ +LQ ++   
Sbjct: 1712 MKELWREVE-ETRTSRE-------------EIFSQNRESEKRLKGLEAEVLRLQEELAAS 1757

Query: 1888 -----QNYKQQVEVAETQANQYLSK-----YKKQ--------QHELNEVKERAEVAESQV 1929
                 Q  + + E+A+  AN  LSK      K+Q        + EL E +  +E+   + 
Sbjct: 1758 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1817

Query: 1930 NKLKIKAREFGKKVQEE 1946
             KL ++      ++  E
Sbjct: 1818 RKLLLQVESLTTELSAE 1834


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  590 bits (1520), Expect = e-168
 Identities = 435/1424 (30%), Positives = 701/1424 (49%), Gaps = 132/1424 (9%)

Query: 53   KCWIPDGENAYIEAEVKGSEDDGTVIVETA--DGESL--SIKEDKIQQMNPPEFEMIE-D 107
            + WIPD E  +  AE+      G  ++     DG  L  S+  + +  +  P+  + E D
Sbjct: 12   RVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGEND 71

Query: 108  MAMLTHLNEASVLHTLKRRYGQW-MIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRS 166
            +  L++L+E +VLH L+ R+ +  +IYTYSG+  V +NPYK LP+Y   ++ AY G+   
Sbjct: 72   LTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMG 131

Query: 167  EAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ 226
            +  PHIFAVA  A++ M  N  NQSI+ +GESGAGKTV++++ ++YFAT++       K 
Sbjct: 132  DMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVS-------KS 184

Query: 227  GA---LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEK 283
            G+   +ED+++ +N I EA GNAKT RNDNSSRFGK+  + F  +  +   ++  YLLEK
Sbjct: 185  GSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244

Query: 284  SRVIFQQAGERNYHIFYQILSG--QKELHDLLLVSANPSDFHFCSCGAVTV-ESLDDAEE 340
            SRV+FQ   ERNYHIFYQ+ +   Q E   L L SA   +F++   G  TV E ++D  E
Sbjct: 245  SRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAE--EFNYTRMGGNTVIEGVNDRAE 302

Query: 341  LLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLM 400
            ++ T++   +LGF  D +   +K+  AI+H GN++      E    ++   +      L+
Sbjct: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362

Query: 401  GINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALD 460
            G+ S  + + L + +I   +E V +  T  Q   A  AL+K +Y  +F ++V RIN+AL 
Sbjct: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422

Query: 461  AKLSRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEW 520
                +  FIG+LDI GFE  + NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482

Query: 521  VSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580
              I F  D Q  IDLIE  MGIL +L+EEC+ P  TD  +  KL++N   ++   +KP+ 
Sbjct: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541

Query: 581  DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTD 640
                    F + H+A  V Y   G+LEKN+D + + +V + + S   L A+ F+   +  
Sbjct: 542  S----NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597

Query: 641  SAIPFGEKKRKKGAS----------FQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690
            S  PFG     K A             TV S  + +L  LM  L +T PH+VRCI PN  
Sbjct: 598  S--PFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655

Query: 691  KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750
            K+P   D   ++QQLR  GVLE  RI  + +P+R  Y +F  RY IL   T  +  F   
Sbjct: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDK 713

Query: 751  RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810
            ++  + +L  L  D  QY+FG TK+FF+AG +  LE +R ++L +   + Q   +G L R
Sbjct: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773

Query: 811  IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAG-LKEECA 869
             KF   L ER A ++IQ   R    V+          +K    +  + +   G L     
Sbjct: 774  KKF---LRERRAALIIQQYFRGQQTVRK---AITAVALKEAWAAIIIQKHCRGYLVRSLY 827

Query: 870  QL--QKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQL 927
            QL     +    + R  L  ++     E++  ++  +  +  LA    Q        IQL
Sbjct: 828  QLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQL 887

Query: 928  EARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKV 987
              RV+ L +++E++ + N  L  +   L        ++I  LE  L K+   +R  E K 
Sbjct: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKG 947

Query: 988  KNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELE 1047
            K   + V                               EEKL+ L K N +LE Q ++++
Sbjct: 948  KRYRDAV-------------------------------EEKLAKLQKHNSELETQKEQIQ 976

Query: 1048 GALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVE 1107
              L+++ +       EL +   N  L ++  ++++  +R     L +K  EL     K +
Sbjct: 977  LKLQEKTE-------ELKEKMDN--LTKQLFDDVQKEERQ--RMLLEKSFEL-----KTQ 1020

Query: 1108 NEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGG 1167
            + +  +  L++ +K L+ +   L+  +E E  T   ++ E A L++ +  ++E  +E+  
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080

Query: 1168 SSLAQLEITKKQETKFQKLHRDMEEAT------LHFETTSASLKKRHADSLAE------- 1214
                ++++ K  +++ +++   M E T         E   + L     + L E       
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA 1140

Query: 1215 LEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLC----TLYEERLHE 1270
             EG  +  + ++   +  K   + E++ L  +V  +++   + +KL      + E   HE
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200

Query: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK--------EALINQLSREKSNFTR 1322
             T +L     +  D   Q ++L  +  +   RL E+        E L NQL R +     
Sbjct: 1201 VT-RLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGT 1259

Query: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQ 1382
            Q + L  Q E  TK +  L   +Q+ Q   D L++Q+E E EVK    +  S        
Sbjct: 1260 QRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEAS-------- 1311

Query: 1383 WRMKYENNVIQRTEDLED-AKKELAIRLQEAAEAMGVANARNAS 1425
             R+  EN  ++   D++D   K+L  +++  ++ +G AN  ++S
Sbjct: 1312 -RLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSS 1354



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 124/571 (21%), Positives = 245/571 (42%), Gaps = 77/571 (13%)

Query: 1299 FLRRLEEKEALINQLSREKSNFTRQIEDLRG------------QLEKETKSQSALAHALQ 1346
            + + LEE +A+I Q         R+ + +R             +L+K+ + Q+   H L 
Sbjct: 850  YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909

Query: 1347 KAQRDCDLLRE-QYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKEL 1405
            +       LR    E+ Q+++AEL +  +         R  YE    ++ +   DA +E 
Sbjct: 910  EKLTSLAALRAGDVEKIQKLEAELEKAATH--------RRNYE----EKGKRYRDAVEEK 957

Query: 1406 AIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKAL 1465
              +LQ+           N+ LE  + Q+QL+L +   +L           +K     K L
Sbjct: 958  LAKLQK----------HNSELETQKEQIQLKLQEKTEEL----------KEKMDNLTKQL 997

Query: 1466 ADWKQKHEESQALLDAS--------QKEVQALSTELLKLKNTYEESIVGQETLRREN--- 1514
             D  QK E  + LL+ S        +K++Q+L  E+  LK   +E +  Q  +  E+   
Sbjct: 998  FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALK---DEKMQLQHLVEGEHVTS 1054

Query: 1515 KNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQ 1574
              L+ E++ L+ QV    K ++E EK  +L++ +K +V+  ++  +  +    S+I    
Sbjct: 1055 DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL 1110

Query: 1575 LELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSS---LDSEAKSRIEVTRLKKKME 1631
            LE  + + ++  +LS +D E  N   +     + L+ +   L+S  +S+ +     +K  
Sbjct: 1111 LESYDIE-DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCY---EKEI 1166

Query: 1632 EDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNS 1691
            E LN   + LS     + +  +    +   I+    +L     +  D K+Q++  E++  
Sbjct: 1167 EALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQ 1226

Query: 1692 LLQSEL----EDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVA 1747
             L+  L    E ++   E+       S+EE  E T+R  L   QN     +K+KL   + 
Sbjct: 1227 DLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQRKAL-EAQNEIHTKEKEKLIDKIQ 1283

Query: 1748 RMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQK 1807
             MQ+ ++ + ++ +   E       EA+ L+ E +  ++ +   +R  + ++  +  L K
Sbjct: 1284 EMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343

Query: 1808 RLAEAEQMALMGSRKQIQKLESRVRELEGEL 1838
             + +A  +      K+   +    RE E +L
Sbjct: 1344 TIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 124/588 (21%), Positives = 246/588 (41%), Gaps = 129/588 (21%)

Query: 801  QARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLF-------FKIKPLVK 853
            QA ++G L R +++K+LEE  A+IL ++  RA++A + +  +R F       ++++ L K
Sbjct: 838  QAYSRGFLARRRYRKMLEEHKAVILQKY-ARAWLARRRFQSIRRFVLNIQLTYRVQRLQK 896

Query: 854  SSE--------VGEEVAGL---------------------------------------KE 866
              E        + E++  L                                       +E
Sbjct: 897  KLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEE 956

Query: 867  ECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQ 926
            + A+LQK   + E Q+E+++ K    T+E  + +  L  +       EE+   L++   +
Sbjct: 957  KLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFE 1016

Query: 927  L-----EARVKELSERVE-------------EEEEINSE----LTARGRKLEDECFELKK 964
            L     E +++ L E ++             E E + S+      AR  K      E +K
Sbjct: 1017 LKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEK 1076

Query: 965  EIDDLETMLVKSEK----EKRTTEHKVKNLT------------------EEVEFLNED-- 1000
            EI+ L+   +  EK    +KR    K+  +T                  E++E LNED  
Sbjct: 1077 EIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGE 1136

Query: 1001 ----ISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKA 1056
                   L +A +V+ E+H Q+  D +  E+++ +L+   + L Q+++ L+    +E   
Sbjct: 1137 LWFAYEGLKKATRVL-ESHFQSQKDCY--EKEIEALNFKVVHLSQEINHLQKLFREENDI 1193

Query: 1057 RMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQL 1116
              +   E+       +L  E+M   +  Q+    E +K++LE+ ++N + E  KG + +L
Sbjct: 1194 NESIRHEV------TRLTSENMMIPDFKQQISELEKQKQDLEI-RLNEQAEKMKGKLEEL 1246

Query: 1117 QKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEIT 1176
               +   Q +    ++ LEA+     K + +  D  Q++ + ++ L++   +  ++++  
Sbjct: 1247 SNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETE-SEVKCN 1305

Query: 1177 KKQETKFQKL-HRDMEE---------ATLHFETTSASLKKRHADSLAELEGQVENLQQVK 1226
             +QE     L +RD+EE           L  +  + S     A+ +    G  E L  ++
Sbjct: 1306 FRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQ 1365

Query: 1227 QKLEKDKSDLQLEVDDLLTR---VEQMTRAKANAEKLCTLYEERLHEA 1271
             K E +   +Q  + DL  R   V  +    A+   +C  Y + L++A
Sbjct: 1366 YKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDA 1413



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 118/523 (22%), Positives = 231/523 (44%), Gaps = 79/523 (15%)

Query: 1182 KFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVD 1241
            +FQ + R +    L +      L+K+  D   E  G VE L  +      D   +Q    
Sbjct: 874  RFQSIRRFVLNIQLTYRVQR--LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQ---- 927

Query: 1242 DLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLR 1301
             L   +E+    + N E+    Y + + E  AKL K     ++L  QK ++  +  E   
Sbjct: 928  KLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHN---SELETQKEQIQLKLQEKTE 984

Query: 1302 RLEEKEALINQLSREKSNFTRQIEDLRGQLEK--ETKSQSALAHALQKAQRDCDLLREQY 1359
             L+EK   ++ L+++  +  ++ E  R  LEK  E K+Q      +Q  + +   L+++ 
Sbjct: 985  ELKEK---MDNLTKQLFDDVQKEERQRMLLEKSFELKTQD-YEKQIQSLKEEIKALKDEK 1040

Query: 1360 EEEQEVKAELHRTLSKVNAEM------VQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
             + Q +    H T   + AE+      V+   ++E  +        D +K +  + +E  
Sbjct: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100

Query: 1414 EAMGVANAR---NASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470
            E M     +   +  +E  R +L +E  + L++ G++  A   L        K      +
Sbjct: 1101 EKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGL--------KKATRVLE 1152

Query: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRREN---KNLQEEISNLTNQ 1527
             H +SQ   D  +KE++AL+ +++ L          Q+  R EN   ++++ E++ LT++
Sbjct: 1153 SHFQSQK--DCYEKEIEALNFKVVHLSQEINHL---QKLFREENDINESIRHEVTRLTSE 1207

Query: 1528 ---VREGTKNLTEMEKVKKLIE----EEKTEVQVTLEETEGALERNESKILHFQLELLEA 1580
               + +  + ++E+EK K+ +E    E+  +++  LEE    L R++ +    Q + LEA
Sbjct: 1208 NMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEE-GTQRKALEA 1266

Query: 1581 KAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ 1640
            + E+  K  EK++ I+  +  Q+ +                    LKK+ E      E +
Sbjct: 1267 QNEIHTK--EKEKLIDKIQEMQEAS------------------DHLKKQFET-----ESE 1301

Query: 1641 LSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQV 1683
            + C  RQ  EA++    L ++ +DL+ +LD   ++   L++QV
Sbjct: 1302 VKCNFRQ--EASR----LTLENRDLEEELDMKDRVIKKLQDQV 1338



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 43/203 (21%), Positives = 92/203 (45%), Gaps = 18/203 (8%)

Query: 1746 VARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDL 1805
            V R+QK+ E+  +E     EK    A   A   E+++K +  +      R N E+     
Sbjct: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK---- 946

Query: 1806 QKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQ 1865
             KR  +A +  L   +K   +LE++  +++ +L          Q     L+  +  LT Q
Sbjct: 947  GKRYRDAVEEKLAKLQKHNSELETQKEQIQLKL----------QEKTEELKEKMDNLTKQ 996

Query: 1866 AEEDKKNLSRMQTQMDK-LQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEV 1924
              +D +   R +  ++K  +LK Q+Y++Q++  + +      +  + QH +      ++ 
Sbjct: 997  LFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDG 1056

Query: 1925 AESQVNKLKIKAR---EFGKKVQ 1944
             +++V +L  + +   EF K+++
Sbjct: 1057 LKAEVARLSKQVKTISEFEKEIE 1079


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  564 bits (1453), Expect = e-160
 Identities = 463/1570 (29%), Positives = 748/1570 (47%), Gaps = 214/1570 (13%)

Query: 53   KCWIPDGENAYIEAEVKGSEDDG--TVIVETADGESLSI----KEDKIQQMNPPEFEMIE 106
            + WIPD E  +  AE+      G   +++   +G+ L      K  ++  +  P+  + E
Sbjct: 12   RVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGE 71

Query: 107  -DMAMLTHLNEASVLHTLKRRY-GQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR 164
             D+  L++L+E +VLH L+ R+    +IYTY G+  V INPY+ LP+Y ++++ AY G+ 
Sbjct: 72   NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 165  RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRK 224
              +  PHIFAVA  A++ M  +  NQSI+ +GESGAGKTV++K+ ++YFAT++       
Sbjct: 132  MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS--- 188

Query: 225  KQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKS 284
             +  +E++++ +N I+E+ GNAKT RNDNSSRFGK+I + F  R  +   ++  YLLEKS
Sbjct: 189  -EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKS 247

Query: 285  RVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLA 343
            RV+FQ   ERNYHIFYQ+ +  K     +L   N  +F++   G +  +E +DDA+E+  
Sbjct: 248  RVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAH 307

Query: 344  TEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGIN 403
            T QA  +LG     + G +++   I+H GN+ F  +  +        E       LMG++
Sbjct: 308  TRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 404  SSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKL 463
              E+   L H ++    E   +  +  Q T A  AL+K +Y ++F W+V  +N+AL + +
Sbjct: 368  YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427

Query: 464  SRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
             +  FIG+LDI GFE  E NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W  I
Sbjct: 428  KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLI 487

Query: 524  GFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK 583
             F  D Q CI+LIE  +GIL +L+EEC  PK TD T+  KL++ H  K    +KP+   K
Sbjct: 488  DF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNK 546

Query: 584  KFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF---ENYMSTD 640
                 F + H+A  V Y   G+LEKNKD + E  + V + S  ++L  LF   E  +S  
Sbjct: 547  A----FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPT 602

Query: 641  SAIPFGE-------KKRKKGASFQ-------TVASLHKENLNKLMTNLKSTAPHFVRCIN 686
            SA   G         K  KG   Q       TV    + +L+ LM  L +T PH+VRCI 
Sbjct: 603  SATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIK 662

Query: 687  PNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSK 746
            PN  K P   D    +QQLR  GVLE  RI   GFP+R  Y +F  RY +L  +   K  
Sbjct: 663  PNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ---KDV 719

Query: 747  FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQG 806
                ++  + +L  L +D  +Y+FG TK+FF+AG +  LE +R ++L       Q   +G
Sbjct: 720  LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779

Query: 807  KLMRIKFQKILEERDALILIQWNIRAFMA---------VKNWPWMRLFFKIKPLVKSSEV 857
             L+R   +K L  R A I +Q  +R + A          K    ++ ++++  + +  ++
Sbjct: 780  WLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836

Query: 858  GEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQC 917
                  + +  + L+  L ++ +++   + K V + +     + +   ++   A +  QC
Sbjct: 837  RRAATIVLQ--SYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQC 894

Query: 918  ---------------------EWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLE 956
                                 E   K  I +E ++ +L  +V+E+ +    L  +   LE
Sbjct: 895  CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLE 954

Query: 957  ----DECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQ 1012
                 E  +L+ +++ L+     SE+E +    +V +L EE+  L +D+ +     K ++
Sbjct: 955  GIYNSETEKLRSDLERLQL----SEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010

Query: 1013 EAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLK 1072
            E      D    E E+L S    NLK E  +      L+QE++A             N +
Sbjct: 1011 E----HADRYKQETEQLVS----NLKEENTL------LKQEKEAL------------NHR 1044

Query: 1073 LNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKE 1132
            + +++ E  E+ ++ L EE ++ EL+L+    + +N       L      L+ +  DLKE
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN-------LLNEFSRLEERYDDLKE 1097

Query: 1133 KLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLE--ITKKQETKFQKLHRDM 1190
                E T    + +     T      NE  E +  S +A++E   ++ +E   +K+  DM
Sbjct: 1098 ----EMTLMVHVPKPGHKRTDSTHSSNES-EYIFSSEIAEMEDIPSRTEEPSEKKVPLDM 1152

Query: 1191 EEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQM 1250
                      S  LK         L+ +V  L+Q KQ ++          D+L  + EQ+
Sbjct: 1153 ----------SLFLK---------LQKRVTELEQEKQVMQ----------DELDRKEEQV 1183

Query: 1251 TRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALI 1310
             R+KA         EER     A+L+  +    +L ++  KL +E  E  + L EK A  
Sbjct: 1184 LRSKAKE-------EERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSA-- 1234

Query: 1311 NQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELH 1370
                                   E  +  A A+ +   Q     L    EE    K E+ 
Sbjct: 1235 ----------------------PEVTAPGAPAYRVLMEQ-----LTSVSEELDVRKEEVL 1267

Query: 1371 RTLSKVNAEMVQWRMKYENNVI-QRTEDLEDAKKELAIRLQEAAE-AMGVANARNASLER 1428
               S++ ++    + K + N +   T  LED +K     +++  E A      +  +   
Sbjct: 1268 ILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQK-----MKDKGEIAQAYIGLKETNRSS 1322

Query: 1429 ARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQA 1488
            A    +L     L  + +    A RL + QLQS       K+ HE      +A + E+Q+
Sbjct: 1323 ALDYHELNEDGELWLVYEGLKQANRLLESQLQS------QKRSHENE---AEALRGEIQS 1373

Query: 1489 LSTELLKLKNTYEESIVGQETL----RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL 1544
            L  E     N  ++ ++ Q        R   +LQ EI+ LTN   E    + ++EK  K 
Sbjct: 1374 LKEE-----NNRQQQLLAQNLQLPPEARIEASLQHEITRLTN---ENLDLMEQLEKQDKT 1425

Query: 1545 IEEEKTEVQV 1554
            + + K +++V
Sbjct: 1426 VRKLKKQLKV 1435



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 121/556 (21%), Positives = 231/556 (41%), Gaps = 97/556 (17%)

Query: 1388 ENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKV 1447
            EN ++Q    +++  K+    +++     G+ N+    L     +LQL   +A    G+V
Sbjct: 926  ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985

Query: 1448 RS-----AAARLDQKQLQSGKALAD-----WKQKHEESQALLDAS----QKEVQALSTEL 1493
             S     A  R D +Q +S K   +     +KQ+ E+  + L       ++E +AL+  +
Sbjct: 986  LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045

Query: 1494 LK----LKNTYEESIVGQETLRRE---------NKNLQEEISNLTNQVREGTKNLTEMEK 1540
            ++    +  T E+ +V +ET + E          +NL  E S L  +  +  + +T M  
Sbjct: 1046 VQQAKEMTETMEKKLV-EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104

Query: 1541 VKK-----------------LIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
            V K                 +   E  E++     TE   E+     +   L+L +   E
Sbjct: 1105 VPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1584 LERK-------LSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNE 1636
            LE++       L  K+E++   + K++       + L+ E+  R E+    KK++ +LNE
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224

Query: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696
            +   LS   +   E T + G    ++  L  QL       + + E++ V +    +L+S+
Sbjct: 1225 LRKALS--EKSAPEVT-APGAPAYRV--LMEQL-------TSVSEELDVRKEEVLILRSQ 1272

Query: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEV 1756
            L               +S++E ++  +  N   T +T LL   +K+        K+  E+
Sbjct: 1273 L---------------VSQKEAIQPKDDKNTM-TDSTILLEDVQKM--------KDKGEI 1308

Query: 1757 VQECQNAEEKAKKAAIEAANLSE--ELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQ 1814
             Q     +E  + +A++   L+E  EL    + +    R  E+  Q+    QKR  E E 
Sbjct: 1309 AQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQS----QKRSHENEA 1364

Query: 1815 MALMGSRKQIQKLESRVRELEG---ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKK 1871
             AL G  + +++  +R ++L     +L  E R  A  Q    RL     +L  Q E+  K
Sbjct: 1365 EALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDK 1424

Query: 1872 NLSRMQTQMDKLQLKV 1887
             + +++ Q+     K+
Sbjct: 1425 TVRKLKKQLKVFAKKI 1440



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 120/599 (20%), Positives = 241/599 (40%), Gaps = 70/599 (11%)

Query: 799  LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVG 858
            + Q R +G L R  +++ +    A+I +Q   R  MA +    +++  +     K   +G
Sbjct: 868  IIQKRVRGWLARTHYKRSMH---AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIG 924

Query: 859  -----------------------EEVAGLK----EECAQLQKALEKSEFQREELKA---K 888
                                   E++  L+     E  +L+  LE+ +   EE K    +
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGR 984

Query: 889  QVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSEL 948
             +SL +E   L   L+  +     +EE  +   +   QL + +KE +  +++E+E  +  
Sbjct: 985  VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044

Query: 949  TARGRKLEDECFELK--KEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNR 1006
              +  K   E  E K  +E   LE  L       +   ++   L E  + L E+++ +  
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLM-- 1102

Query: 1007 AAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHK 1066
               V +  H++T D  H   E     S    ++E      E   E++    M+   +L K
Sbjct: 1103 -VHVPKPGHKRT-DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK 1160

Query: 1067 LEGNLKLNRESMEN-LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQT 1125
                L+  ++ M++ L+  +  +     K+E       +++E E     +L+   K+L+ 
Sbjct: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220

Query: 1126 QIKDLKEKLEAERTTRAKMERERA------DLTQDLADLNERLEEV---GGSSLAQLEIT 1176
            ++ +L++ L  +           A       LT    +L+ R EEV       ++Q E  
Sbjct: 1221 ELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI 1280

Query: 1177 KKQETK------------FQKLHRDMEEATLHF---ETT-SASLKKRHADSLAELEGQVE 1220
            + ++ K             QK+    E A  +    ET  S++L     +   EL    E
Sbjct: 1281 QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYE 1340

Query: 1221 NLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQ 1280
             L+Q  + LE   S LQ +        E + R +  + K     +++L     +L    +
Sbjct: 1341 GLKQANRLLE---SQLQSQKRSHENEAEAL-RGEIQSLKEENNRQQQLLAQNLQLPPEAR 1396

Query: 1281 LANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLR-GQLEKETKSQ 1338
            +   L  + T+L +E+ + + +LE+++  + +L ++   F ++I +L  GQ+E  +  Q
Sbjct: 1397 IEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ 1455



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 111/634 (17%), Positives = 249/634 (39%), Gaps = 74/634 (11%)

Query: 1204 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTL 1263
            + KR    L      VE  +++   +E     LQ +VD+     + +     N E +   
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1264 YEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQ 1323
              E+L     +L    + A     +   L  E  +  + LE+  +    +      + ++
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019

Query: 1324 IEDLRGQLEKET----KSQSALAHAL-QKAQRDCDLLREQYEEEQEVKAELHRTLSKVNA 1378
             E L   L++E     + + AL H + Q+A+   + + ++  EE +          ++  
Sbjct: 1020 TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK----------QLEL 1069

Query: 1379 EMVQWRMKYEN--NVIQRTED-LEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435
            ++   R++Y+N  N   R E+  +D K+E+ + +          ++ ++S     ++ + 
Sbjct: 1070 DLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSS-----NESEY 1124

Query: 1436 ELGDALSDLGKVRSAAARLDQKQ--------LQSGKALADWKQKHEESQALLDASQKEV- 1486
                 ++++  + S      +K+        L+  K + + +Q+ +  Q  LD  +++V 
Sbjct: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL 1184

Query: 1487 --QALSTELLKLKNT-YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEM----E 1539
              +A   E  +++    E   + ++ L  ENK L+ E++ L   + E  K+  E+     
Sbjct: 1185 RSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSE--KSAPEVTAPGA 1242

Query: 1540 KVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFR 1599
               +++ E+ T V   L+     + + E  IL  QL        + +K + + ++ +N  
Sbjct: 1243 PAYRVLMEQLTSVSEELD-----VRKEEVLILRSQL--------VSQKEAIQPKDDKNTM 1289

Query: 1600 RKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQ 1659
                  ++ +Q   D    ++  +   +      L+  EL        V E  K   +L 
Sbjct: 1290 TDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLL 1349

Query: 1660 IQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELL 1719
                         +QL S  +     AE     +QS  E+    Q+   +  +L  E  +
Sbjct: 1350 ------------ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARI 1397

Query: 1720 EAT--ERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANL 1777
            EA+    I     +N  L+ Q +K +  V +++K+ +   ++    E    +       +
Sbjct: 1398 EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQII 1457

Query: 1778 SEEL------KKKQDTIAHLERTRENMEQTITDL 1805
             E +      +K++D    LE  +E+ ++ + +L
Sbjct: 1458 DEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNL 1491


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  558 bits (1438), Expect = e-158
 Identities = 410/1318 (31%), Positives = 655/1318 (49%), Gaps = 157/1318 (11%)

Query: 53   KCWIPDGENAYIEAEVKGSEDDG--TVIVETADGESLSI----KEDKIQQMNPPEFEMIE 106
            + WIPD E  +  AE+      G   +++   +G+ L      K  ++  +  P+  + E
Sbjct: 12   RVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGE 71

Query: 107  -DMAMLTHLNEASVLHTLKRRY-GQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR 164
             D+  L++L+E +VLH L+ R+    +IYTY G+  V INPY+ LP+Y ++++ AY G+ 
Sbjct: 72   NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 165  RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRK 224
              +  PHIFAVA  A++ M  +  NQSI+ +GESGAGKTV++K+ ++YFAT++       
Sbjct: 132  MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS--- 188

Query: 225  KQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKS 284
             +  +E++++ +N I+E+ GNAKT RNDNSSRFGK+I + F  R  +   ++  YLLEKS
Sbjct: 189  -EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKS 247

Query: 285  RVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLA 343
            RV+FQ   ERNYHIFYQ+ +  K     +L   N  +F++   G +  +E +DDA+E+  
Sbjct: 248  RVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAH 307

Query: 344  TEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGIN 403
            T QA  +LG     + G +++   I+H GN+ F  +  +        E       LMG++
Sbjct: 308  TRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 404  SSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKL 463
              E+   L H ++    E   +  +  Q T A  AL+K +Y ++F W+V  +N+AL + +
Sbjct: 368  YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427

Query: 464  SRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
             +  FIG+LDI GFE  E NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W  I
Sbjct: 428  KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLI 487

Query: 524  GFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK 583
             F  D Q CI+LIE  +GIL +L+EEC  PK TD T+  KL++ H  K    +KP+   K
Sbjct: 488  DF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNK 546

Query: 584  KFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF---ENYMSTD 640
                 F + H+A  V Y   G+LEKNKD + E  + V + S  ++L  LF   E  +S  
Sbjct: 547  A----FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPT 602

Query: 641  SAIPFGE-------KKRKKGASFQ-------TVASLHKENLNKLMTNLKSTAPHFVRCIN 686
            SA   G         K  KG   Q       TV    + +L+ LM  L +T PH+VRCI 
Sbjct: 603  SATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIK 662

Query: 687  PNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSK 746
            PN  K P   D    +QQLR  GVLE  RI   GFP+R  Y +F  RY +L  +   K  
Sbjct: 663  PNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ---KDV 719

Query: 747  FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQG 806
                ++  + +L  L +D  +Y+FG TK+FF+AG +  LE +R ++L       Q   +G
Sbjct: 720  LSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRG 779

Query: 807  KLMRIKFQKILEERDALILIQWNIRAFMA---------VKNWPWMRLFFKIKPLVKSSEV 857
             L+R   +K L  R A I +Q  +R + A          K    ++ ++++  + +  ++
Sbjct: 780  WLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKI 836

Query: 858  GEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQC 917
                  + +  + L+  L ++ +++   + K V + +     + +   ++   A +  QC
Sbjct: 837  RRAATIVLQ--SYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQC 894

Query: 918  ---------------------EWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLE 956
                                 E   K  I +E ++ +L  +V+E+ +    L  +   LE
Sbjct: 895  CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLE 954

Query: 957  ----DECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQ 1012
                 E  +L+ +++ L+     SE+E +    +V +L EE+  L +D+ +     K ++
Sbjct: 955  GIYNSETEKLRSDLERLQL----SEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010

Query: 1013 EAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLK 1072
            E      D    E E+L S    NLK E  +      L+QE++A             N +
Sbjct: 1011 E----HADRYKQETEQLVS----NLKEENTL------LKQEKEAL------------NHR 1044

Query: 1073 LNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKE 1132
            + +++ E  E+ ++ L EE ++ EL+L+    + +N       L      L+ +  DLKE
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN-------LLNEFSRLEERYDDLKE 1097

Query: 1133 KLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLE--ITKKQETKFQKLHRDM 1190
                E T    + +     T      NE  E +  S +A++E   ++ +E   +K+  DM
Sbjct: 1098 ----EMTLMVHVPKPGHKRTDSTHSSNES-EYIFSSEIAEMEDIPSRTEEPSEKKVPLDM 1152

Query: 1191 EEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQM 1250
                      S  LK         L+ +V  L+Q KQ ++          D+L  + EQ+
Sbjct: 1153 ----------SLFLK---------LQKRVTELEQEKQVMQ----------DELDRKEEQV 1183

Query: 1251 TRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEA 1308
             R+KA         EER     A+L+  +    +L ++  KL +E  E  + L EK A
Sbjct: 1184 LRSKAKE-------EERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSA 1234



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 118/553 (21%), Positives = 230/553 (41%), Gaps = 85/553 (15%)

Query: 1388 ENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKV 1447
            EN ++Q    +++  K+    +++     G+ N+    L     +LQL   +A    G+V
Sbjct: 926  ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985

Query: 1448 RS-----AAARLDQKQLQSGKALAD-----WKQKHEESQALLDAS----QKEVQALSTEL 1493
             S     A  R D +Q +S K   +     +KQ+ E+  + L       ++E +AL+  +
Sbjct: 986  LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045

Query: 1494 LK----LKNTYEESIVGQETLRRE---------NKNLQEEISNLTNQVREGTKNLTEMEK 1540
            ++    +  T E+ +V +ET + E          +NL  E S L  +  +  + +T M  
Sbjct: 1046 VQQAKEMTETMEKKLV-EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104

Query: 1541 VKK-----------------LIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583
            V K                 +   E  E++     TE   E+     +   L+L +   E
Sbjct: 1105 VPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1584 LERK-------LSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNE 1636
            LE++       L  K+E++   + K++       + L+ E+  R E+    KK++ +LNE
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224

Query: 1637 MELQLSCANRQVSEATKS--------LGQLQIQIKDLQMQLDDSTQLNSDL---KEQVAV 1685
            +   LS   +   E T          + QL    ++L ++ ++   L S L   KE +  
Sbjct: 1225 LRKALS--EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282

Query: 1686 AERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEAD 1745
             + +N++  S +  L  +Q+  ++G        L+ T R+       + L SQK+  E +
Sbjct: 1283 KDDKNTMTDSTIL-LEDVQKMKDKGEIAQAYIGLKETNRL-----LESQLQSQKRSHENE 1336

Query: 1746 VARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDL 1805
               ++ E + +       EE  ++  + A NL    + + +     E TR   E    DL
Sbjct: 1337 AEALRGEIQSL------KEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNEN--LDL 1388

Query: 1806 QKRLAEAEQMALMGSRKQIQKLESRVRELE-GELE----GEIRRSAEAQRGARRLERCIK 1860
             ++L E +   +   +KQ++    ++ ELE G++E    G+I           R E+  +
Sbjct: 1389 MEQL-EKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ 1447

Query: 1861 ELTYQAEEDKKNL 1873
             +    +ED++ L
Sbjct: 1448 GMLEYKKEDEQKL 1460



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 109/581 (18%), Positives = 236/581 (40%), Gaps = 61/581 (10%)

Query: 799  LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVG 858
            + Q R +G L R  +++ +    A+I +Q   R  MA +    +++  +     K   +G
Sbjct: 868  IIQKRVRGWLARTHYKRSMH---AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIG 924

Query: 859  -----------------------EEVAGLK----EECAQLQKALEKSEFQREELKA---K 888
                                   E++  L+     E  +L+  LE+ +   EE K    +
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGR 984

Query: 889  QVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSEL 948
             +SL +E   L   L+  +     +EE  +   +   QL + +KE +  +++E+E  +  
Sbjct: 985  VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044

Query: 949  TARGRKLEDECFELK--KEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNR 1006
              +  K   E  E K  +E   LE  L       +   ++   L E  + L E+++ +  
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLM-- 1102

Query: 1007 AAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHK 1066
               V +  H++T D  H   E     S    ++E      E   E++    M+   +L K
Sbjct: 1103 -VHVPKPGHKRT-DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQK 1160

Query: 1067 LEGNLKLNRESMEN-LESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQT 1125
                L+  ++ M++ L+  +  +     K+E       +++E E     +L+   K+L+ 
Sbjct: 1161 RVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKN 1220

Query: 1126 QIKDLKEKLEAERTTRAKMERERA------DLTQDLADLNERLEEVGGSSLAQLEITKKQ 1179
            ++ +L++ L  +           A       LT    +L+ R EEV    L    +++K+
Sbjct: 1221 ELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEV--LILRSQLVSQKE 1278

Query: 1180 ETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELE-GQVENLQQVKQKLEKDKSDLQL 1238
              + +     M ++T+  E      K +    +A+   G  E  + ++ +L+  K   + 
Sbjct: 1279 AIQPKDDKNTMTDSTILLEDVQ---KMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHEN 1335

Query: 1239 EVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGE 1298
            E + L   ++ +              +++L     +L    ++   L  + T+L +E+ +
Sbjct: 1336 EAEALRGEIQSLKEENNR--------QQQLLAQNLQLPPEARIEASLQHEITRLTNENLD 1387

Query: 1299 FLRRLEEKEALINQLSREKSNFTRQIEDLR-GQLEKETKSQ 1338
             + +LE+++  + +L ++   F ++I +L  GQ+E  +  Q
Sbjct: 1388 LMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ 1428



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 96/540 (17%), Positives = 225/540 (41%), Gaps = 58/540 (10%)

Query: 1204 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTL 1263
            + KR    L      VE  +++   +E     LQ +VD+     + +     N E +   
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1264 YEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQ 1323
              E+L     +L    + A     +   L  E  +  + LE+  +    +      + ++
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019

Query: 1324 IEDLRGQLEKET----KSQSALAHAL-QKAQRDCDLLREQYEEEQEVKAELHRTLSKVNA 1378
             E L   L++E     + + AL H + Q+A+   + + ++  EE +          ++  
Sbjct: 1020 TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK----------QLEL 1069

Query: 1379 EMVQWRMKYEN--NVIQRTED-LEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435
            ++   R++Y+N  N   R E+  +D K+E+ + +          ++ ++S     ++ + 
Sbjct: 1070 DLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSS-----NESEY 1124

Query: 1436 ELGDALSDLGKVRSAAARLDQKQ--------LQSGKALADWKQKHEESQALLDASQKEV- 1486
                 ++++  + S      +K+        L+  K + + +Q+ +  Q  LD  +++V 
Sbjct: 1125 IFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL 1184

Query: 1487 --QALSTELLKLKNT-YEESIVGQETLRRENKNLQEEISNLTNQVREGTKN--------- 1534
              +A   E  +++    E   + ++ L  ENK L+ E++ L   + E +           
Sbjct: 1185 RSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPA 1244

Query: 1535 ----LTEMEKVKKLIEEEKTEVQV----TLEETEGALERNESKILHFQLELLEAKAELER 1586
                + ++  V + ++  K EV +     + + E    +++   +     LLE   +++ 
Sbjct: 1245 YRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD 1304

Query: 1587 K--LSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS-RIEVTRLKKK--MEEDLNEMELQL 1641
            K  +++    ++   R  +  + S + S ++EA++ R E+  LK++   ++ L    LQL
Sbjct: 1305 KGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1364

Query: 1642 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAV-AERRNSLLQSELEDL 1700
                R  +     + +L  +  DL  QL+   +    LK+Q+ V A++   L   ++E++
Sbjct: 1365 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENI 1424


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  551 bits (1421), Expect = e-156
 Identities = 449/1509 (29%), Positives = 726/1509 (48%), Gaps = 187/1509 (12%)

Query: 53   KCWIPDGENAYIEAEVKGSEDDGTVIV------ETADGESLSIKEDKIQQMNPPEFEMIE 106
            + WIPD +  +  AE+     +G   +      ET     + ++ +++  +  P+  + E
Sbjct: 12   RVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71

Query: 107  -DMAMLTHLNEASVLHTLKRRYGQWM-IYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR 164
             D+  L++L+E +VLH LK R+ +   IYTY G+  V INPY+ LP+Y ++V+  Y G+ 
Sbjct: 72   NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131

Query: 165  RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRK 224
              +  PHIFAVA  A++ M  + +NQSI+ +GESGAGKTV++K+ ++YFAT+        
Sbjct: 132  MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191

Query: 225  KQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKS 284
                +E++++ ++ I+EA GNAKT RNDNSSRFGK+I++ F  R  +   ++  YLLEKS
Sbjct: 192  ----IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKS 247

Query: 285  RVIFQQAGERNYHIFYQILS--GQKELHDLLLVSANPSDFHFCSCGAVT-VESLDDAEEL 341
            RV+FQ   ERNYHIFYQ+ +  G  E  +L L SA   DF + S G  T +E +DDAE+ 
Sbjct: 248  RVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDDAEDF 305

Query: 342  LATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAF--L 399
              T QA  +LG     +   +K+  +I+H G++   Q  R+    +   ++   + F  L
Sbjct: 306  EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-QAERDGDSCSISPQDVYLSNFCRL 364

Query: 400  MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
            +G+  S++   L H ++   +E   +  +++QV  A  AL+K +Y ++F W+V  IN+AL
Sbjct: 365  LGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL 424

Query: 460  DAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIE 519
               L +  FIG+LDI GFE  E NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I 
Sbjct: 425  HTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484

Query: 520  WVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPK 579
            W  I F  D Q CIDLIE  +GIL +L+EEC  PK TD  +  KL+D H   S H QKP+
Sbjct: 485  WTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPR 542

Query: 580  PDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF------ 633
                     F +VH+A  V Y   G+LEKN+D + E  + + + S   L+A LF      
Sbjct: 543  MS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598

Query: 634  ----------ENYMSTDSAIP---FGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPH 680
                       + +S  SA P      K+ KK    Q   SLH      LM  L +T PH
Sbjct: 599  VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLH-----LLMETLNATTPH 653

Query: 681  FVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPR 740
            +VRCI PN  K+P   DP   +QQLR  GVLE  RI   G+P+R  Y DF  RY +L   
Sbjct: 654  YVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL--- 710

Query: 741  TFPKSKFVSSRKAA--EELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFT 798
               K +  ++ K A    +L +L  D  +++FG TK+FF+AG +  LE +R ++      
Sbjct: 711  -VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769

Query: 799  LFQARAQGKLMRIKFQKI----------------------LEERDALILIQWNIRAFMAV 836
            + Q   +G L ++K+ ++                      L    A +++Q + R   A 
Sbjct: 770  MIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRAR 829

Query: 837  KNWPWM-RLFFKIKPLVKSSEVGEEVAG--LKEECAQLQKALEKSEFQREELKAKQVSLT 893
            + +  + R    I+   ++  V        ++ +   +QK +     +R   + +  ++ 
Sbjct: 830  QAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIV 889

Query: 894  QEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
             +    +L+ + E + L       E L +  + +E +V +L  +++E+   N E      
Sbjct: 890  IQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ---NKEFKTLSE 946

Query: 954  KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
            +L         E++ L+  LV    ++   E     L EEVE L  ++ + +   K++++
Sbjct: 947  QLSVTTSTYTMEVERLKKELV--HYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004

Query: 1014 AHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEG----------------------ALE 1051
            AH +  D+L    ++++ L + N  L+ + ++L                         LE
Sbjct: 1005 AHSREKDEL---RKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061

Query: 1052 QERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELE------------- 1098
            +ER    N  +E  +LE      R+ M  ++ +  H      +  LE             
Sbjct: 1062 EERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEI 1121

Query: 1099 ------LSQMN----SKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERER 1148
                  L Q+      K   +  +  +LQK V+EL+ + K L+ +LE      +K  + +
Sbjct: 1122 GDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK--KVQ 1179

Query: 1149 ADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRH 1208
            A+  Q   DL+    ++  +SL + E+    E++ +KL  D+ E        +      H
Sbjct: 1180 AEPPQTDIDLDPN-ADLAYNSLKRQEL----ESENKKLKNDLNELRKAVADQATQNNSSH 1234

Query: 1209 A--DSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEE 1266
               DS + L  Q   L+   ++LE  K ++ L +   +   +Q   A  NAE        
Sbjct: 1235 GSPDSYSLLLNQ---LKLAHEELEVRKEEV-LILRTQIVSADQRRLAGRNAEP-----NI 1285

Query: 1267 RLHEATAKLDKVTQLANDLAA--------QKTKLW---SESGEF---LRRLEEKEALIN- 1311
                +    +K     + + A         KT+ W   +E GE     + L++   L+  
Sbjct: 1286 NARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEA 1345

Query: 1312 QLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRD-CD--LLREQYEEEQEVKAE 1368
            QL  +      ++E L+ QLE       AL   + K Q+  C   LL  + + E  V+ E
Sbjct: 1346 QLQAQSLEHEEEVEHLKAQLE-------ALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQE 1398

Query: 1369 LHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLER 1428
            + R L+  N ++ +   K E N           KK+L I +++A + +  A A  A  ER
Sbjct: 1399 ISR-LTNENLDLKELVEKLEKNE-------RKLKKQLKIYMKKAQD-LEAAQAL-AQSER 1448

Query: 1429 ARHQLQLEL 1437
             RH+L  ++
Sbjct: 1449 KRHELNRQV 1457



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 127/587 (21%), Positives = 256/587 (43%), Gaps = 82/587 (13%)

Query: 1391 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGD------ALSDL 1444
            VIQ    +  A++EL     EA  A  +    N  +E    QLQ ++ +       LS+ 
Sbjct: 889  VIQCAFRMLKARRELKALRIEARSAEHLKRL-NVGMENKVVQLQRKIDEQNKEFKTLSEQ 947

Query: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYE--E 1502
              V ++   ++ ++L+  K L  ++Q   E  +L    Q+EV++L TEL +  +  +  E
Sbjct: 948  LSVTTSTYTMEVERLK--KELVHYQQSPGEDTSL--RLQEEVESLRTELQRAHSERKILE 1003

Query: 1503 SIVGQET---------LRRENKNLQEEISNLTNQV-----REGTKNLTEMEKVKKLIEEE 1548
                +E          L +EN  L++E   L NQ+      E  +N  +   +KK +EEE
Sbjct: 1004 DAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEE 1063

Query: 1549 KTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLS-----EKDEEIENFRRKQ- 1602
            ++  Q  ++E     +R ++  L  ++ +++      R  S     E D    +    + 
Sbjct: 1064 RSRYQNLVKEYSQLEQRYDN--LRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEI 1121

Query: 1603 QCTIDSLQS----SLDSEAKSRIEVTRLKKKMEE-DLNEMELQLSCANRQVSEATKSLGQ 1657
              T D+LQ      L+  A       +L+K++ E +    +LQ+    R+  ++ K    
Sbjct: 1122 GDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKK---- 1177

Query: 1658 LQIQIKDLQMQLDDSTQL-NSDLKEQVAVAERRNSLLQSELEDLR------SLQEQTERG 1710
            +Q +     + LD +  L  + LK Q    E  N  L+++L +LR      + Q  +  G
Sbjct: 1178 VQAEPPQTDIDLDPNADLAYNSLKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHG 1235

Query: 1711 R-----------RLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQE 1759
                        +L+ EEL    E + +  TQ  S  + +++L    A     A      
Sbjct: 1236 SPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVS--ADQRRLAGRNAEPNINAR---SS 1290

Query: 1760 CQNAEEKA-KKAAIEAANLSEELKKKQDTIAHLERTRE--NMEQTITDLQKRLAEAEQMA 1816
              N+E+   ++ AIEA +   +   K +   +L    E     Q +  + + L    Q  
Sbjct: 1291 WPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQ 1350

Query: 1817 LMGSRKQIQKLESRVRELEGELEGE-------IRRSAEAQRGARRLERCIKELTYQAEED 1869
             +   ++++ L++++  L+ E++ +       +  S EAQ     +++ I  LT +  + 
Sbjct: 1351 SLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQ-VEFGVQQEISRLTNENLDL 1409

Query: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELN 1916
            K+ + +++    KL+ +++ Y ++ +  + +A Q L++ ++++HELN
Sbjct: 1410 KELVEKLEKNERKLKKQLKIYMKKAQ--DLEAAQALAQSERKRHELN 1454



 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 110/546 (20%), Positives = 240/546 (43%), Gaps = 65/546 (11%)

Query: 1451 AARLDQKQLQSGKAL-ADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQET 1509
            A R++ +  +  K L    + K  + Q  +D   KE + LS +L    +TY   +   E 
Sbjct: 905  ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEV---ER 961

Query: 1510 LRRENKNLQEEISNLTN-QVREGTKNL-TEMEKV---KKLIEE----EKTEVQVTLE--E 1558
            L++E  + Q+     T+ +++E  ++L TE+++    +K++E+    EK E++  +   E
Sbjct: 962  LKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE 1021

Query: 1559 TEGALERNESKILHFQLELLEAKAELERKLSEKD---EEIENFRRKQQCTIDSLQSSLDS 1615
             E AL ++E + L+ Q+ L ++K E  +   +++   +E+E  R + Q  +         
Sbjct: 1022 QENALLKDEKEQLNNQI-LCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR 1080

Query: 1616 EAKSRIEVTRLKKKMEEDLNEM-ELQLSCANRQVSEATKSLGQLQI---QIKDLQMQ--- 1668
                R E+T +K+      N   +  L   +   S +T  +G  +    Q++++ ++   
Sbjct: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA 1140

Query: 1669 LDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLF 1728
            +D +  L   L+++V   E+    LQ +LE  +  Q+ +++ +    +  ++     +L 
Sbjct: 1141 MDMTVFLK--LQKRVRELEQERKKLQVQLE--KREQQDSKKVQAEPPQTDIDLDPNADLA 1196

Query: 1729 YT--QNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLS---EELKK 1783
            Y   +   L S+ KKL+ D+  ++K   +   +  ++       ++    L    EEL+ 
Sbjct: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256

Query: 1784 KQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG------- 1836
            +++ +  L        Q ++  Q+RLA       + +R      E  V + +        
Sbjct: 1257 RKEEVLILRT------QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGV 1310

Query: 1837 -------ELEGEIRRSAE---AQRGARRLERCIK-ELTYQAEEDKKNLSRMQTQMDKLQL 1885
                   E  G +    E   A +G +++ R ++ +L  Q+ E ++ +  ++ Q++ L+ 
Sbjct: 1311 CQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKE 1370

Query: 1886 KVQNYKQ---QVEVAETQANQYLSKYKKQQHELNE---VKERAEVAESQVNKLKIKAREF 1939
            ++   +Q   Q  +   +A       ++     NE   +KE  E  E    KLK + + +
Sbjct: 1371 EMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIY 1430

Query: 1940 GKKVQE 1945
             KK Q+
Sbjct: 1431 MKKAQD 1436


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  496 bits (1277), Expect = e-140
 Identities = 428/1677 (25%), Positives = 767/1677 (45%), Gaps = 201/1677 (11%)

Query: 52   KKCWIPDGENAYIEAEVKGSE---DDGTVIVETA-DGESLSIKEDKIQQMNPPEFEMIED 107
            +K W+   +   + +++K  E    +G V V+   DG  L + ED +++ N P  + +ED
Sbjct: 350  EKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLED 409

Query: 108  MAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSE 167
            +A L +LNE+SVLHTL++RYG  +++TY+G   + + P     VY ++VM  +KG RR +
Sbjct: 410  LASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRRED 469

Query: 168  APPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQG 227
              PHI+AVA  A++ ML +R++QSI+  G SG+GKT + +H++QY ATIA +  S  K  
Sbjct: 470  MAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--SGNKVF 527

Query: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
            ++E +     T+LEAFGN+ T+ N N++RF + + + F   G ++S  I   LLEK RV 
Sbjct: 528  SVE-KWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVA 586

Query: 288  FQQAGERNYHIFYQILSG-----QKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELL 342
             + A E  +++FY +L+      + ELH  L   A  + F      A   E    A++  
Sbjct: 587  RRPASEATFNVFYYLLACGDGTLRTELH--LNHLAENNVFGIVPL-AKPEEKQKAAQQFS 643

Query: 343  ATEQAMDILGFLPDEKYGCYKLTGAIMHFGNM-KFKQKPREEQLEADGTENADKAAFLMG 401
              + AM +LG  PDE+  C+ +  AI H G     K+     + +    E A KAA+L+G
Sbjct: 644  KLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLG 703

Query: 402  INSSELVKCLIHPRIKVGNEYVT---------------RGQTIEQVTCAVGALSKSMYER 446
             +  EL   +   + K G    +                G  +  + C  G ++  +Y  
Sbjct: 704  CSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG-MAAGLYSE 762

Query: 447  MFKWLVARINRALDAKLSRQFFIGILDITGFEILEYN------SLEQLCINFTNEKLQQF 500
            +F  LV+ +NRAL +       + I+D  GF+  E        S E+LC N+T ++LQ+ 
Sbjct: 763  LFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRL 822

Query: 501  FNWHMFVLEQEEYKKESIEW---------------VSIGFGLDLQACIDLIEKPMGILSI 545
            F+   FV E E YK+E+IE                V       L   +   ++  G+L +
Sbjct: 823  FHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWL 882

Query: 546  LEEECMFPKATDLTFKTKLFD-------NHFGKSVHLQKPKPDKKKFEAHFELVHYAGV- 597
            LEEE + P A++ T   +LF        +  G+S  L   KP       HF L H  G  
Sbjct: 883  LEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPH------HFLLGHSHGTN 936

Query: 598  -VPYNISGWLEKNK-DLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGA- 654
             V YN++GWL   K +   +    + Q S  +++++LF     + + +       + G+ 
Sbjct: 937  WVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQ 996

Query: 655  -----------SFQT-VASLHKENL--------NKLMTNLKSTAPHFVRCINPNVNKIPG 694
                       +F T +A++ K++L        + L+  +K +  HFV C  P      G
Sbjct: 997  LALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAG 1056

Query: 695  -----------------------------ILDPYLVLQQLRCNGVLEGTRICREGFPNRL 725
                                          LD  L+  QLR + +L+  R+ R+G+P+ +
Sbjct: 1057 EPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHM 1116

Query: 726  QYADFKQRYCILNPRTFPKSK----FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGF 781
             +++F++R+ +L P    K       V  R+A EELL  L+++ +    G+++VFF+AG 
Sbjct: 1117 VFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGT 1176

Query: 782  LGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPW 841
            L +LE  RDE+ S+  TLFQA  +G L R  F+K   +  A+  +Q NI+    VK+WPW
Sbjct: 1177 LARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPW 1236

Query: 842  MRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL 901
             +LF  ++PL++     E++    EE  QL+  LEK+E +R EL+     L    ++L  
Sbjct: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTS 1296

Query: 902  QLQAEQETLANVEEQCEWLIKSKIQLEARVKEL-------------------SERVEEEE 942
            +L  E+ T  +  +  +     +++ E  +KEL                     R+    
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356

Query: 943  EINSEL---TARG-------RKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992
            EIN E+    A G       R + +  F  K+   + E  L   ++ KR  E ++ +L  
Sbjct: 1357 EINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQA 1416

Query: 993  EVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQ 1052
            + E     + +L +  + +    Q T   L  ++ +   L K   + + ++ +     ++
Sbjct: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476

Query: 1053 ERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGL 1112
            E+  R   +RE   L       ++ +E  +       +++   E EL  ++S+   ++  
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536

Query: 1113 VAQLQKTVKELQTQIKDLKEKLEAERTT-----------RAKMERERADLTQDLADLNER 1161
            +A+++K +++L+ ++KD +E+L+ +  T             +MER R   ++++   +E 
Sbjct: 1537 LAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596

Query: 1162 LEEVGGS---SLAQLEITKKQETK-FQKLHRDMEEATLHFETTSASLKKRHADSLAELEG 1217
            +EE   S    L Q+E+  ++E +  QK+ R+  E      T S  + +R  +S   L  
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656

Query: 1218 QVENLQQVKQKLE------KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1271
             ++  + +    +      K+ +  + E+  L  ++E+     A A K     E  + + 
Sbjct: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716

Query: 1272 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR-------EKSNFTRQI 1324
              ++D + +    L  Q ++L  E  E   RLEE +  +N+L +       + S    QI
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776

Query: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384
             DL+ QLE+  K +  L   LQ  Q   + L    E+    K+ + R  +K+    ++ R
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAKIRE--LETR 1830

Query: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444
            +++E   ++R E L    KE   +L E  +    A  R    +    +LQ +L D   ++
Sbjct: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE---KEQNKRLQRQLRDTKEEM 1887

Query: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESI 1504
            G++    A   +K+ +    L   +  ++  QA L  + K +  L            ++ 
Sbjct: 1888 GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDL------------QAA 1935

Query: 1505 VGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEG 1561
            +  E    EN++L   + ++  + ++    L     V   +E+    V+  L + +G
Sbjct: 1936 IEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNKG 1992



 Score =  154 bits (389), Expect = 8e-37
 Identities = 174/803 (21%), Positives = 363/803 (45%), Gaps = 79/803 (9%)

Query: 1169 SLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQK 1228
            +LA+LE  + ++T     +  + +A           KKR    LA        ++ V++ 
Sbjct: 1176 TLARLEEQRDEQTS---RNLTLFQAACRGYLARQHFKKRKIQDLA--------IRCVQKN 1224

Query: 1229 LEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQ 1288
            ++K+K         L T V  +   + + E++    EE + +  +KL+K  +  N+L   
Sbjct: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNELRLN 1283

Query: 1289 KTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKA 1348
              +L              E+ I++L+ E ++     E     L+ ET  +      +++ 
Sbjct: 1284 SDRL--------------ESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKEL 1329

Query: 1349 QRDCDLLREQYE--EEQEVKAELHRTLSKVNAEMV------QWRMKYENNVIQRTEDLED 1400
            Q   D L++Q E  E + ++A L R  +++N E+       +WR+KYE  V     +++ 
Sbjct: 1330 QTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGGEWRLKYERAV----REVDF 1384

Query: 1401 AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARL-----D 1455
             KK L    QE  + + V       LER    LQ +  ++   L +++    RL     D
Sbjct: 1385 TKKRLQ---QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441

Query: 1456 QKQLQSGKAL-------------ADWKQKHEESQA---LLDASQKEVQALSTELLKLKNT 1499
             K    G+ +             ++  Q HEE+Q      +  Q+E   L  E   LK  
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQ 1501

Query: 1500 YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEET 1559
             EE  +      ++  +L+ E+ ++++Q  +   +L +++K  + +E +  + +  L+E 
Sbjct: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561

Query: 1560 EGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS 1619
             G ++  E   L  ++E+   +    +++  +DEE+E  R+  Q  +  ++  L+ E + 
Sbjct: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED 1621

Query: 1620 RIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDL 1679
            + +V R K+++E  L  +  Q+   NR+  E+ K   +L+  +K  +  L D+ QL  D 
Sbjct: 1622 KQKVLREKRELEGKLATLSDQV---NRRDFESEK---RLRKDLKRTKALLADA-QLMLDH 1674

Query: 1680 KEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQK 1739
             +  A ++R  + L+++LE+         + R+  E E+ +   +I+      T+L  Q 
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734

Query: 1740 KKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME 1799
             +L+ +   +Q   EE  ++     +K K A  +A+    ++   Q  +    + ++ ++
Sbjct: 1735 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQ 1794

Query: 1800 QTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCI 1859
            + +  LQ ++   EQ   M  +  + + E+++RELE  LE E  +    +  A RL+  +
Sbjct: 1795 EKLQALQSQVEFLEQS--MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852

Query: 1860 KELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQV-EVAETQANQYLSKYKKQQHELNEV 1918
            ++LT + ++     +R + Q  +LQ ++++ K+++ E+A  +A     +  +++HEL   
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA-----EASRKKHELEMD 1907

Query: 1919 KERAEVAESQVN-KLKIKAREFG 1940
             E  E A   +   LK+  +  G
Sbjct: 1908 LESLEAANQSLQADLKLAFKRIG 1930



 Score =  142 bits (358), Expect = 3e-33
 Identities = 172/777 (22%), Positives = 347/777 (44%), Gaps = 102/777 (13%)

Query: 979  EKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSS-LSKANL 1037
            E + +E +++N  EE++ L    SKL +A K   E        L +  ++L S +S+   
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLR---SKLEKAEKERNE--------LRLNSDRLESRISELTS 1296

Query: 1038 KLEQQVDELEGA---LEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRK 1094
            +L  + +  E A   L+ E   R+  E+E+ +L+      ++ ME +E       E +  
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM------EVMEA 1350

Query: 1095 KELELSQMNSKVENEKG----------LVAQLQKTVKELQTQIKDLKEKLEAERTTRAKM 1144
            + +  +++N +V+++             V ++  T K LQ + +D   KLE E+  + ++
Sbjct: 1351 RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFED---KLEVEQQNKRQL 1407

Query: 1145 ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSA-- 1202
            ER   DL  D  +    L+++              + K Q+L  ++++  LH E      
Sbjct: 1408 ERRLGDLQADSEESQRALQQL--------------KKKCQRLTAELQDTKLHLEGQQVRN 1453

Query: 1203 ---SLKKRHADS---LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKAN 1256
                 K+R  DS    A  E Q E LQ  ++KL+++K  L  E   L  ++E+     A 
Sbjct: 1454 HELEKKQRRFDSELSQAHEEAQREKLQ--REKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511

Query: 1257 AEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSRE 1316
              +     E  L + +++  K       +  Q   L ++  +    L+E+   I  L + 
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571

Query: 1317 KSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDL--------LREQYEEEQEV--- 1365
            K     ++E +R    KE +S+      +++A++ C          L E+YE++Q+V   
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRD---EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628

Query: 1366 KAELHRTLSKVNAEMVQWRMKYENNV---IQRTEDL-EDAKKELAIRLQEAAEAMGVANA 1421
            K EL   L+ ++ ++ +   + E  +   ++RT+ L  DA+  L      A     +A  
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688

Query: 1422 RN---------ASLERARHQLQLELGDA---LSDLGKVRSAAA-RLDQKQLQSGKALADW 1468
            +N         A+  +AR  +++E+ D    + D+ K ++A   +L + Q +  +     
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748

Query: 1469 KQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQV 1528
            ++  E+   L+   +  V   S +L ++ +   +     E   +E + LQE++  L +QV
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL----EEANKEKQELQEKLQALQSQV 1804

Query: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588
                +++ +   V +  E +  E++  LE     ++R ES     +  + +   E ++++
Sbjct: 1805 EFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI 1863

Query: 1589 SEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQV 1648
            + ++ E E  +R Q+   D+ +  +   A+   E +R K ++E DL  +E         +
Sbjct: 1864 AAENREKEQNKRLQRQLRDT-KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL 1922

Query: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQ------SELED 1699
              A K +G LQ  I+D +M+ D++  L + L++ V   ++R + L+      SELED
Sbjct: 1923 KLAFKRIGDLQAAIED-EMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELED 1978



 Score =  104 bits (259), Expect = 1e-21
 Identities = 115/615 (18%), Positives = 271/615 (44%), Gaps = 47/615 (7%)

Query: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRM---KYENNVIQRTEDLEDAKKELAI 1407
            +  L  EQ   + E   +L   L K   E  + R+   + E+ + + T +L D +     
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG-- 1305

Query: 1408 RLQEAAEAMGVANARNASLERARHQLQLELGDALS--------DLGKVRSAAARLDQKQL 1459
              + A++ +    A     E+   +LQ +  DAL         ++ + R   A     ++
Sbjct: 1306 --ESASQLLDAETAERLRAEKEMKELQTQY-DALKKQMEVMEMEVMEARLIRAAEINGEV 1362

Query: 1460 QSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQE 1519
                A  +W+ K+E +   +D ++K          +L+  +E+ +   E  ++  + L+ 
Sbjct: 1363 DDDDAGGEWRLKYERAVREVDFTKK----------RLQQEFEDKL---EVEQQNKRQLER 1409

Query: 1520 EISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLE 1579
             + +L     E  + L +++K  + +  E  + ++ LE  +      E K   F  EL +
Sbjct: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQ 1469

Query: 1580 AKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMEL 1639
            A  E +R+  ++ E+++  +        SL+  L+ +       T+    +E +L ++  
Sbjct: 1470 AHEEAQREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 1640 QLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKE-QVAVAERRNSLLQSELE 1698
            Q S     +++  K L  L+ ++KD + +LD+       L++ ++ +      + Q+  +
Sbjct: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588

Query: 1699 DLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQ 1758
            ++ S  E+ E  R+  +++L +   ++   Y     +L +K++LE  +A +   +++V +
Sbjct: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNR 1645

Query: 1759 ECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALM 1818
                +E++ +K       L   L   Q  + HL+ +  +  + I  L+ +L E+E     
Sbjct: 1646 RDFESEKRLRKDLKRTKAL---LADAQLMLDHLKNSAPSKRE-IAQLKNQLEESE-FTCA 1700

Query: 1819 GSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQ- 1877
             + K  + +E  + +L  +++   +     +    RL+R   E+  + EED+++++ +  
Sbjct: 1701 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1760

Query: 1878 ------TQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNK 1931
                   Q  +   ++ + + Q+E A  +  +   K +  Q ++ E  E++ V +S V++
Sbjct: 1761 KHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV-EFLEQSMVDKSLVSR 1819

Query: 1932 LKIKAREFGKKVQEE 1946
             + K RE   +++ E
Sbjct: 1820 QEAKIRELETRLEFE 1834



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 78/318 (24%), Positives = 156/318 (49%), Gaps = 18/318 (5%)

Query: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696
            +E+QLS    Q+    + + QL+ +++  + + ++  +LNSD  E       R S L SE
Sbjct: 1247 IEVQLS--EEQIRNKDEEIQQLRSKLEKAEKERNE-LRLNSDRLES------RISELTSE 1297

Query: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV--ARMQKEAE 1754
            L D R+  E   +       E L A + +    TQ  +L  Q + +E +V  AR+ + AE
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357

Query: 1755 ---EVVQECQNAEEKAK--KAAIEAANLSEELKKK-QDTIAHLERTRENMEQTITDLQKR 1808
               EV  +    E + K  +A  E     + L+++ +D +   ++ +  +E+ + DLQ  
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417

Query: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEE 1868
             +E  Q AL   +K+ Q+L + +++ +  LEG+  R+ E ++  RR +  + +   +A+ 
Sbjct: 1418 -SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476

Query: 1869 DKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQ 1928
            +K    ++Q + D L  +  + KQQ+E  +     +  K    + EL ++  +    E+ 
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536

Query: 1929 VNKLKIKAREFGKKVQEE 1946
            + K+K + R+   KV+++
Sbjct: 1537 LAKVKKQLRDLEAKVKDQ 1554


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  494 bits (1272), Expect = e-139
 Identities = 421/1641 (25%), Positives = 756/1641 (46%), Gaps = 190/1641 (11%)

Query: 52   KKCWIPDGENAYIEAEVKGSE---DDGTVIVETA-DGESLSIKEDKIQQMNPPEFEMIED 107
            +K W+   +   + +++K  E    +G V V+   DG  L + ED +++ N P  + +ED
Sbjct: 350  EKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLED 409

Query: 108  MAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSE 167
            +A L +LNE+SVLHTL++RYG  +++TY+G   + + P     VY ++VM  +KG RR +
Sbjct: 410  LASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRRED 469

Query: 168  APPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQG 227
              PHI+AVA  A++ ML +R++QSI+  G SG+GKT + +H++QY ATIA +  S  K  
Sbjct: 470  MAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--SGNKVF 527

Query: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
            ++E +     T+LEAFGN+ T+ N N++RF + + + F   G ++S  I   LLEK RV 
Sbjct: 528  SVE-KWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVA 586

Query: 288  FQQAGERNYHIFYQILSG-----QKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELL 342
             + A E  +++FY +L+      + ELH  L   A  + F      A   E    A++  
Sbjct: 587  RRPASEATFNVFYYLLACGDGTLRTELH--LNHLAENNVFGIVPL-AKPEEKQKAAQQFS 643

Query: 343  ATEQAMDILGFLPDEKYGCYKLTGAIMHFGNM-KFKQKPREEQLEADGTENADKAAFLMG 401
              + AM +LG  PDE+  C+ +  AI H G     K+     + +    E A KAA+L+G
Sbjct: 644  KLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLG 703

Query: 402  INSSELVKCLIHPRIKVGNEYVT---------------RGQTIEQVTCAVGALSKSMYER 446
             +  EL   +   + K G    +                G  +  + C  G ++  +Y  
Sbjct: 704  CSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG-MAAGLYSE 762

Query: 447  MFKWLVARINRALDAKLSRQFFIGILDITGFEILEYN------SLEQLCINFTNEKLQQF 500
            +F  LV+ +NRAL +       + I+D  GF+  E        S E+LC N+T ++LQ+ 
Sbjct: 763  LFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRL 822

Query: 501  FNWHMFVLEQEEYKKESIEW---------------VSIGFGLDLQACIDLIEKPMGILSI 545
            F+   FV E E YK+E+IE                V       L   +   ++  G+L +
Sbjct: 823  FHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWL 882

Query: 546  LEEECMFPKATDLTFKTKLFD-------NHFGKSVHLQKPKPDKKKFEAHFELVHYAGV- 597
            LEEE + P A++ T   +LF        +  G+S  L   KP       HF L H  G  
Sbjct: 883  LEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPH------HFLLGHSHGTN 936

Query: 598  -VPYNISGWLEKNK-DLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGA- 654
             V YN++GWL   K +   +    + Q S  +++++LF     + + +       + G+ 
Sbjct: 937  WVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQ 996

Query: 655  -----------SFQT-VASLHKENL--------NKLMTNLKSTAPHFVRCINPNVNKIPG 694
                       +F T +A++ K++L        + L+  +K +  HFV C  P      G
Sbjct: 997  LALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAG 1056

Query: 695  -----------------------------ILDPYLVLQQLRCNGVLEGTRICREGFPNRL 725
                                          LD  L+  QLR + +L+  R+ R+G+P+ +
Sbjct: 1057 EPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHM 1116

Query: 726  QYADFKQRYCILNPRTFPKSK----FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGF 781
             +++F++R+ +L P    K       V  R+A EELL  L+++ +    G+++VFF+AG 
Sbjct: 1117 VFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGT 1176

Query: 782  LGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPW 841
            L +LE  RDE+ S+  TLFQA  +G L R  F+K   +  A+  +Q NI+    VK+WPW
Sbjct: 1177 LARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPW 1236

Query: 842  MRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL 901
             +LF  ++PL++     E++    EE  QL+  LEK+E +R EL+     L    ++L  
Sbjct: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTS 1296

Query: 902  QLQAEQETLANVEEQCEWLIKSKIQLEARVKEL-------------------SERVEEEE 942
            +L  E+ T  +  +  +     +++ E  +KEL                     R+    
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356

Query: 943  EINSEL---TARG-------RKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992
            EIN E+    A G       R + +  F  K+   + E  L   ++ KR  E ++ +L  
Sbjct: 1357 EINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQA 1416

Query: 993  EVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQ 1052
            + E     + +L +  + +    Q T   L  ++ +   L K   + + ++ +     ++
Sbjct: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476

Query: 1053 ERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGL 1112
            E+  R   +RE   L       ++ +E  +       +++   E EL  ++S+   ++  
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536

Query: 1113 VAQLQKTVKELQTQIKDLKEKLEAERTT-----------RAKMERERADLTQDLADLNER 1161
            +A+++K +++L+ ++KD +E+L+ +  T             +MER R   ++++   +E 
Sbjct: 1537 LAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596

Query: 1162 LEEVGGS---SLAQLEITKKQETK-FQKLHRDMEEATLHFETTSASLKKRHADSLAELEG 1217
            +EE   S    L Q+E+  ++E +  QK+ R+  E      T S  + +R  +S   L  
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656

Query: 1218 QVENLQQVKQKLE------KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1271
             ++  + +    +      K+ +  + E+  L  ++E+     A A K     E  + + 
Sbjct: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716

Query: 1272 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR-------EKSNFTRQI 1324
              ++D + +    L  Q ++L  E  E   RLEE +  +N+L +       + S    QI
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776

Query: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384
             DL+ QLE+  K +  L   LQ  Q   + L    E+    K+ + R  +K+    ++ R
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAKIRE--LETR 1830

Query: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444
            +++E   ++R E L    KE   +L E  +    A  R    +    +LQ +L D   ++
Sbjct: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE---KEQNKRLQRQLRDTKEEM 1887

Query: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL-KLKNTYEES 1503
            G++    A   +K+ +    L   +  ++  QA L  + K +  L   +  ++++   E 
Sbjct: 1888 GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENED 1947

Query: 1504 IVGQETLRRENKNLQEEISNL 1524
            ++  E     +  L++ +  +
Sbjct: 1948 LINSEGDSDVDSELEDRVDGV 1968



 Score =  154 bits (389), Expect = 8e-37
 Identities = 174/803 (21%), Positives = 363/803 (45%), Gaps = 79/803 (9%)

Query: 1169 SLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQK 1228
            +LA+LE  + ++T     +  + +A           KKR    LA        ++ V++ 
Sbjct: 1176 TLARLEEQRDEQTS---RNLTLFQAACRGYLARQHFKKRKIQDLA--------IRCVQKN 1224

Query: 1229 LEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQ 1288
            ++K+K         L T V  +   + + E++    EE + +  +KL+K  +  N+L   
Sbjct: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNELRLN 1283

Query: 1289 KTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKA 1348
              +L              E+ I++L+ E ++     E     L+ ET  +      +++ 
Sbjct: 1284 SDRL--------------ESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKEL 1329

Query: 1349 QRDCDLLREQYE--EEQEVKAELHRTLSKVNAEMV------QWRMKYENNVIQRTEDLED 1400
            Q   D L++Q E  E + ++A L R  +++N E+       +WR+KYE  V     +++ 
Sbjct: 1330 QTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGGEWRLKYERAV----REVDF 1384

Query: 1401 AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARL-----D 1455
             KK L    QE  + + V       LER    LQ +  ++   L +++    RL     D
Sbjct: 1385 TKKRLQ---QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441

Query: 1456 QKQLQSGKAL-------------ADWKQKHEESQA---LLDASQKEVQALSTELLKLKNT 1499
             K    G+ +             ++  Q HEE+Q      +  Q+E   L  E   LK  
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQ 1501

Query: 1500 YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEET 1559
             EE  +      ++  +L+ E+ ++++Q  +   +L +++K  + +E +  + +  L+E 
Sbjct: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561

Query: 1560 EGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS 1619
             G ++  E   L  ++E+   +    +++  +DEE+E  R+  Q  +  ++  L+ E + 
Sbjct: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED 1621

Query: 1620 RIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDL 1679
            + +V R K+++E  L  +  Q+   NR+  E+ K   +L+  +K  +  L D+ QL  D 
Sbjct: 1622 KQKVLREKRELEGKLATLSDQV---NRRDFESEK---RLRKDLKRTKALLADA-QLMLDH 1674

Query: 1680 KEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQK 1739
             +  A ++R  + L+++LE+         + R+  E E+ +   +I+      T+L  Q 
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734

Query: 1740 KKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME 1799
             +L+ +   +Q   EE  ++     +K K A  +A+    ++   Q  +    + ++ ++
Sbjct: 1735 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQ 1794

Query: 1800 QTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCI 1859
            + +  LQ ++   EQ   M  +  + + E+++RELE  LE E  +    +  A RL+  +
Sbjct: 1795 EKLQALQSQVEFLEQS--MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852

Query: 1860 KELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQV-EVAETQANQYLSKYKKQQHELNEV 1918
            ++LT + ++     +R + Q  +LQ ++++ K+++ E+A  +A     +  +++HEL   
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA-----EASRKKHELEMD 1907

Query: 1919 KERAEVAESQVN-KLKIKAREFG 1940
             E  E A   +   LK+  +  G
Sbjct: 1908 LESLEAANQSLQADLKLAFKRIG 1930



 Score =  134 bits (338), Expect = 7e-31
 Identities = 171/771 (22%), Positives = 341/771 (44%), Gaps = 105/771 (13%)

Query: 979  EKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSS-LSKANL 1037
            E + +E +++N  EE++ L    SKL +A K   E        L +  ++L S +S+   
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLR---SKLEKAEKERNE--------LRLNSDRLESRISELTS 1296

Query: 1038 KLEQQVDELEGA---LEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRK 1094
            +L  + +  E A   L+ E   R+  E+E+ +L+      ++ ME +E       E +  
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM------EVMEA 1350

Query: 1095 KELELSQMNSKVENEKG----------LVAQLQKTVKELQTQIKDLKEKLEAERTTRAKM 1144
            + +  +++N +V+++             V ++  T K LQ + +D   KLE E+  + ++
Sbjct: 1351 RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFED---KLEVEQQNKRQL 1407

Query: 1145 ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSA-- 1202
            ER   DL  D  +    L+++              + K Q+L  ++++  LH E      
Sbjct: 1408 ERRLGDLQADSEESQRALQQL--------------KKKCQRLTAELQDTKLHLEGQQVRN 1453

Query: 1203 ---SLKKRHADS---LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKAN 1256
                 K+R  DS    A  E Q E LQ  ++KL+++K  L  E   L  ++E+     A 
Sbjct: 1454 HELEKKQRRFDSELSQAHEEAQREKLQ--REKLQREKDMLLAEAFSLKQQLEEKDMDIAG 1511

Query: 1257 AEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSRE 1316
              +     E  L + +++  K       +  Q   L ++  +    L+E+   I  L + 
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571

Query: 1317 KSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDL--------LREQYEEEQEV--- 1365
            K     ++E +R    KE +S+      +++A++ C          L E+YE++Q+V   
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRD---EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628

Query: 1366 KAELHRTLSKVNAEMVQWRMKYENNV---IQRTEDL-EDAKKELAIRLQEAAEAMGVANA 1421
            K EL   L+ ++ ++ +   + E  +   ++RT+ L  DA+  L      A     +A  
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688

Query: 1422 RN---------ASLERARHQLQLELGDA---LSDLGKVRSAAA-RLDQKQLQSGKALADW 1468
            +N         A+  +AR  +++E+ D    + D+ K ++A   +L + Q +  +     
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748

Query: 1469 KQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQV 1528
            ++  E+   L+   +  V   S +L ++ +   +     E   +E + LQE++  L +QV
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL----EEANKEKQELQEKLQALQSQV 1804

Query: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588
                +++ +   V +  E +  E++  LE     ++R ES     +  + +   E ++++
Sbjct: 1805 EFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI 1863

Query: 1589 SEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQV 1648
            + ++ E E  +R Q+   D+ +  +   A+   E +R K ++E DL  +E         +
Sbjct: 1864 AAENREKEQNKRLQRQLRDT-KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL 1922

Query: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELED 1699
              A K +G LQ  I+D +M+ D+    N DL     +    +S + SELED
Sbjct: 1923 KLAFKRIGDLQAAIED-EMESDE----NEDL-----INSEGDSDVDSELED 1963



 Score =  104 bits (259), Expect = 1e-21
 Identities = 115/615 (18%), Positives = 271/615 (44%), Gaps = 47/615 (7%)

Query: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRM---KYENNVIQRTEDLEDAKKELAI 1407
            +  L  EQ   + E   +L   L K   E  + R+   + E+ + + T +L D +     
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG-- 1305

Query: 1408 RLQEAAEAMGVANARNASLERARHQLQLELGDALS--------DLGKVRSAAARLDQKQL 1459
              + A++ +    A     E+   +LQ +  DAL         ++ + R   A     ++
Sbjct: 1306 --ESASQLLDAETAERLRAEKEMKELQTQY-DALKKQMEVMEMEVMEARLIRAAEINGEV 1362

Query: 1460 QSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQE 1519
                A  +W+ K+E +   +D ++K          +L+  +E+ +   E  ++  + L+ 
Sbjct: 1363 DDDDAGGEWRLKYERAVREVDFTKK----------RLQQEFEDKL---EVEQQNKRQLER 1409

Query: 1520 EISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLE 1579
             + +L     E  + L +++K  + +  E  + ++ LE  +      E K   F  EL +
Sbjct: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQ 1469

Query: 1580 AKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMEL 1639
            A  E +R+  ++ E+++  +        SL+  L+ +       T+    +E +L ++  
Sbjct: 1470 AHEEAQREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 1640 QLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKE-QVAVAERRNSLLQSELE 1698
            Q S     +++  K L  L+ ++KD + +LD+       L++ ++ +      + Q+  +
Sbjct: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588

Query: 1699 DLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQ 1758
            ++ S  E+ E  R+  +++L +   ++   Y     +L +K++LE  +A +   +++V +
Sbjct: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNR 1645

Query: 1759 ECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALM 1818
                +E++ +K       L   L   Q  + HL+ +  +  + I  L+ +L E+E     
Sbjct: 1646 RDFESEKRLRKDLKRTKAL---LADAQLMLDHLKNSAPSKRE-IAQLKNQLEESE-FTCA 1700

Query: 1819 GSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQ- 1877
             + K  + +E  + +L  +++   +     +    RL+R   E+  + EED+++++ +  
Sbjct: 1701 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1760

Query: 1878 ------TQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNK 1931
                   Q  +   ++ + + Q+E A  +  +   K +  Q ++ E  E++ V +S V++
Sbjct: 1761 KHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV-EFLEQSMVDKSLVSR 1819

Query: 1932 LKIKAREFGKKVQEE 1946
             + K RE   +++ E
Sbjct: 1820 QEAKIRELETRLEFE 1834



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 78/318 (24%), Positives = 156/318 (49%), Gaps = 18/318 (5%)

Query: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696
            +E+QLS    Q+    + + QL+ +++  + + ++  +LNSD  E       R S L SE
Sbjct: 1247 IEVQLS--EEQIRNKDEEIQQLRSKLEKAEKERNE-LRLNSDRLES------RISELTSE 1297

Query: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV--ARMQKEAE 1754
            L D R+  E   +       E L A + +    TQ  +L  Q + +E +V  AR+ + AE
Sbjct: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357

Query: 1755 ---EVVQECQNAEEKAK--KAAIEAANLSEELKKK-QDTIAHLERTRENMEQTITDLQKR 1808
               EV  +    E + K  +A  E     + L+++ +D +   ++ +  +E+ + DLQ  
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417

Query: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEE 1868
             +E  Q AL   +K+ Q+L + +++ +  LEG+  R+ E ++  RR +  + +   +A+ 
Sbjct: 1418 -SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476

Query: 1869 DKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQ 1928
            +K    ++Q + D L  +  + KQQ+E  +     +  K    + EL ++  +    E+ 
Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536

Query: 1929 VNKLKIKAREFGKKVQEE 1946
            + K+K + R+   KV+++
Sbjct: 1537 LAKVKKQLRDLEAKVKDQ 1554


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  489 bits (1260), Expect = e-138
 Identities = 326/945 (34%), Positives = 501/945 (53%), Gaps = 51/945 (5%)

Query: 64  IEAEVKGSEDDGTVIVETADGESLSIKEDK--IQQMNPPEFEMIEDMAMLTHLNEASVLH 121
           I A VK  +     +V+  D E     ++   I+ M+P     +EDM  L  LNEA +L 
Sbjct: 24  IGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILR 83

Query: 122 TLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQ 181
            L  RY   +IYTY+G   V +NPY+ L +Y  E +  Y  K+  E PPHIFA+A+N + 
Sbjct: 84  NLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYF 143

Query: 182 DMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILE 241
           +M  N  +Q  + +GESGAGKT ++K I+Q+ A I+       +   +E Q+++A  ILE
Sbjct: 144 NMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG------QHSWIEQQVLEATPILE 197

Query: 242 AFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQ 301
           AFGNAKT+RNDNSSRFGK+I +HF  RG +    I+ YLLEKSRV  Q   ERNYH+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 302 ILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLATEQAMDILGFLPDEKYG 360
           +L G  E     L     SD+++ + G  +T E   D++E      AM +L F   E + 
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 361 CYKLTGAIMHFGNMKFKQKPRE--EQLEADGTENADKAAFLMGINSSELVKCLIHPRIKV 418
             KL  AI+H GN++++ +  E  +  E   + +   AA L+ +N  +L+ CL    +  
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 419 GNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGIL 472
             E V+   + EQ      A  K +Y R+F W+V +IN A+      D K SR+  IG+L
Sbjct: 378 RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLL 436

Query: 473 DITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQAC 532
           DI GFE    NS EQLCINF NE LQQFF  H+F LEQEEY  ESI+W+ I F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 533 IDLI-EKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFEL 591
           +D+I  KPM I+S+++EE  FPK TD T   KL   H   + ++    P K   E  F +
Sbjct: 496 LDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGI 551

Query: 592 VHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRK 651
            H+AG+V Y   G+LEKN+D L+  ++ +   S N+ +  +F+      + +  G + RK
Sbjct: 552 NHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ------ADVAMGAETRK 605

Query: 652 KGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVL 711
           +     T++S  K +L  LM  L +  P FVRCI PN  K P + D +L ++QLR +G++
Sbjct: 606 RS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMM 662

Query: 712 EGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFG 771
           E  RI R G+P R  + +F +RY +L P   P  K    R   + +  ++   H  ++ G
Sbjct: 663 ETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 772 ITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIR 831
            TK+F K      LE  RD+ ++    L Q   +G   R  F K+   ++A  LIQ + R
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWR 779

Query: 832 AFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQV 890
                KN+  MRL F +++ L +S ++ ++    ++   Q Q A  ++   R+  + +  
Sbjct: 780 GHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ-ARCRAYLVRKAFRHRLW 838

Query: 891 SLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTA 950
           ++      L +Q  A       + +      + + +   R++    R+ EEE++  E++A
Sbjct: 839 AV------LTVQAYARGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSA 886

Query: 951 RGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVE 995
           +  K E E  + ++ +  L     + E +++    + K L E++E
Sbjct: 887 KKAKEEAE-RKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  489 bits (1260), Expect = e-138
 Identities = 326/945 (34%), Positives = 501/945 (53%), Gaps = 51/945 (5%)

Query: 64  IEAEVKGSEDDGTVIVETADGESLSIKEDK--IQQMNPPEFEMIEDMAMLTHLNEASVLH 121
           I A VK  +     +V+  D E     ++   I+ M+P     +EDM  L  LNEA +L 
Sbjct: 24  IGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILR 83

Query: 122 TLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQ 181
            L  RY   +IYTY+G   V +NPY+ L +Y  E +  Y  K+  E PPHIFA+A+N + 
Sbjct: 84  NLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYF 143

Query: 182 DMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILE 241
           +M  N  +Q  + +GESGAGKT ++K I+Q+ A I+       +   +E Q+++A  ILE
Sbjct: 144 NMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG------QHSWIEQQVLEATPILE 197

Query: 242 AFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQ 301
           AFGNAKT+RNDNSSRFGK+I +HF  RG +    I+ YLLEKSRV  Q   ERNYH+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 302 ILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLATEQAMDILGFLPDEKYG 360
           +L G  E     L     SD+++ + G  +T E   D++E      AM +L F   E + 
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 361 CYKLTGAIMHFGNMKFKQKPRE--EQLEADGTENADKAAFLMGINSSELVKCLIHPRIKV 418
             KL  AI+H GN++++ +  E  +  E   + +   AA L+ +N  +L+ CL    +  
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 419 GNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGIL 472
             E V+   + EQ      A  K +Y R+F W+V +IN A+      D K SR+  IG+L
Sbjct: 378 RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLL 436

Query: 473 DITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQAC 532
           DI GFE    NS EQLCINF NE LQQFF  H+F LEQEEY  ESI+W+ I F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 533 IDLI-EKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFEL 591
           +D+I  KPM I+S+++EE  FPK TD T   KL   H   + ++    P K   E  F +
Sbjct: 496 LDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGI 551

Query: 592 VHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRK 651
            H+AG+V Y   G+LEKN+D L+  ++ +   S N+ +  +F+      + +  G + RK
Sbjct: 552 NHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ------ADVAMGAETRK 605

Query: 652 KGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVL 711
           +     T++S  K +L  LM  L +  P FVRCI PN  K P + D +L ++QLR +G++
Sbjct: 606 RS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMM 662

Query: 712 EGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFG 771
           E  RI R G+P R  + +F +RY +L P   P  K    R   + +  ++   H  ++ G
Sbjct: 663 ETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 772 ITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIR 831
            TK+F K      LE  RD+ ++    L Q   +G   R  F K+   ++A  LIQ + R
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWR 779

Query: 832 AFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQV 890
                KN+  MRL F +++ L +S ++ ++    ++   Q Q A  ++   R+  + +  
Sbjct: 780 GHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ-ARCRAYLVRKAFRHRLW 838

Query: 891 SLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTA 950
           ++      L +Q  A       + +      + + +   R++    R+ EEE++  E++A
Sbjct: 839 AV------LTVQAYARGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSA 886

Query: 951 RGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVE 995
           +  K E E  + ++ +  L     + E +++    + K L E++E
Sbjct: 887 KKAKEEAE-RKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  489 bits (1260), Expect = e-138
 Identities = 326/945 (34%), Positives = 501/945 (53%), Gaps = 51/945 (5%)

Query: 64  IEAEVKGSEDDGTVIVETADGESLSIKEDK--IQQMNPPEFEMIEDMAMLTHLNEASVLH 121
           I A VK  +     +V+  D E     ++   I+ M+P     +EDM  L  LNEA +L 
Sbjct: 24  IGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILR 83

Query: 122 TLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQ 181
            L  RY   +IYTY+G   V +NPY+ L +Y  E +  Y  K+  E PPHIFA+A+N + 
Sbjct: 84  NLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYF 143

Query: 182 DMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILE 241
           +M  N  +Q  + +GESGAGKT ++K I+Q+ A I+       +   +E Q+++A  ILE
Sbjct: 144 NMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG------QHSWIEQQVLEATPILE 197

Query: 242 AFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQ 301
           AFGNAKT+RNDNSSRFGK+I +HF  RG +    I+ YLLEKSRV  Q   ERNYH+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 302 ILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLATEQAMDILGFLPDEKYG 360
           +L G  E     L     SD+++ + G  +T E   D++E      AM +L F   E + 
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 361 CYKLTGAIMHFGNMKFKQKPRE--EQLEADGTENADKAAFLMGINSSELVKCLIHPRIKV 418
             KL  AI+H GN++++ +  E  +  E   + +   AA L+ +N  +L+ CL    +  
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 419 GNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGIL 472
             E V+   + EQ      A  K +Y R+F W+V +IN A+      D K SR+  IG+L
Sbjct: 378 RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLL 436

Query: 473 DITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQAC 532
           DI GFE    NS EQLCINF NE LQQFF  H+F LEQEEY  ESI+W+ I F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 533 IDLI-EKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFEL 591
           +D+I  KPM I+S+++EE  FPK TD T   KL   H   + ++    P K   E  F +
Sbjct: 496 LDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGI 551

Query: 592 VHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRK 651
            H+AG+V Y   G+LEKN+D L+  ++ +   S N+ +  +F+      + +  G + RK
Sbjct: 552 NHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ------ADVAMGAETRK 605

Query: 652 KGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVL 711
           +     T++S  K +L  LM  L +  P FVRCI PN  K P + D +L ++QLR +G++
Sbjct: 606 RS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMM 662

Query: 712 EGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFG 771
           E  RI R G+P R  + +F +RY +L P   P  K    R   + +  ++   H  ++ G
Sbjct: 663 ETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722

Query: 772 ITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIR 831
            TK+F K      LE  RD+ ++    L Q   +G   R  F K+   ++A  LIQ + R
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWR 779

Query: 832 AFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQV 890
                KN+  MRL F +++ L +S ++ ++    ++   Q Q A  ++   R+  + +  
Sbjct: 780 GHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ-ARCRAYLVRKAFRHRLW 838

Query: 891 SLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTA 950
           ++      L +Q  A       + +      + + +   R++    R+ EEE++  E++A
Sbjct: 839 AV------LTVQAYARGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSA 886

Query: 951 RGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVE 995
           +  K E E  + ++ +  L     + E +++    + K L E++E
Sbjct: 887 KKAKEEAE-RKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  476 bits (1226), Expect = e-134
 Identities = 304/846 (35%), Positives = 456/846 (53%), Gaps = 54/846 (6%)

Query: 75  GTVIVETADGESLSIKEDK---IQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWM 131
           G V+VE  +G+   I+ +    +  M+P   + ++DM  L  LNEA ++H L  RY Q  
Sbjct: 34  GKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHK 93

Query: 132 IYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQS 191
           IYTY+G   V +NP++ LP+Y  E +  Y  +   E PPH+FA+ANN +  M  N+ +Q 
Sbjct: 94  IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQC 153

Query: 192 ILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILEAFGNAKTLRN 251
            + +GESGAGKT  +K I+Q+ ATI+       +   +E Q+++AN ILEAFGNAKT+RN
Sbjct: 154 CIISGESGAGKTETTKLILQFLATISG------QHSWIEQQVLEANPILEAFGNAKTIRN 207

Query: 252 DNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQKELHD 311
           DNSSRFGK+I ++F   G++    I+ +LLEKSRV  Q   ERNYHIFY +L G      
Sbjct: 208 DNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDK 267

Query: 312 LLLVSANPSDFHFCSCGAVT-VESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMH 370
            LL    PS++H+ + G  T  E L+DA++      AM IL F   E +   KL  AI+H
Sbjct: 268 QLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILH 327

Query: 371 FGNMKFKQKPREEQLEADGTENADKAAF-----LMGINSSELVKCLIHPRIKVGNEYVTR 425
            GN+ F     E     D ++  +  AF     L+ +   EL  CLI   I +  E+VTR
Sbjct: 328 LGNVGFMASVFE---NLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTR 384

Query: 426 GQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGILDITGFEI 479
              I Q      A  K +Y  +F W+V +IN A+      D K  R+  IG+LDI GFE 
Sbjct: 385 SLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRR-AIGLLDIFGFEN 443

Query: 480 LEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIE-K 538
            E NS EQLCINF NE LQQFF  H+F +EQEEY+ E+I W  I +  D +  +DL+  K
Sbjct: 444 FENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTLDLLALK 502

Query: 539 PMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVV 598
           PM I+S+L+EE  FP+ TDLT   KL   H      LQ     K   +A F + H+AG V
Sbjct: 503 PMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ----PKNIHDARFGIAHFAGEV 558

Query: 599 PYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASF-- 656
            Y   G+LEKN+D+L+  ++ +   S N+ L  +F N    ++ +  G  ++ K  +   
Sbjct: 559 YYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIF-NLELAETKLGHGTIRQAKAGNHLF 617

Query: 657 ---------QTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRC 707
                     T+ S  K++L++LM  L +  P+F+RCI PN  K P + D  L L+QLR 
Sbjct: 618 KSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRY 677

Query: 708 NGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEI---D 764
           +G++E   I + GFP R  + +F QR+ +L P      +     K  +  LG  ++    
Sbjct: 678 SGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAM---RMQLQGKLRQMTLGITDVWLRT 734

Query: 765 HTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALI 824
              ++ G TK+F +      LE  R + L +     Q   +G   R +F   L +R A +
Sbjct: 735 DKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEF---LRQRRAAV 791

Query: 825 LIQWNIRAFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQRE 883
            +Q   R +   +N+  + + F +++ + +S  +  +   +++   QLQ AL +    R+
Sbjct: 792 TLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQ-ALCRGYLVRQ 850

Query: 884 ELKAKQ 889
           +++AK+
Sbjct: 851 QVQAKR 856


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,561,007
Number of Sequences: 37866
Number of extensions: 2778886
Number of successful extensions: 47873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 671
Number of HSP's successfully gapped in prelim test: 1378
Number of HSP's that attempted gapping in prelim test: 12225
Number of HSP's gapped (non-prelim): 12629
length of query: 1946
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1829
effective length of database: 13,817,196
effective search space: 25271651484
effective search space used: 25271651484
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.