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Search of human proteins with 14589891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
(829 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 1686 0.0
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 922 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 638 0.0
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 616 e-176
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 497 e-140
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 381 e-105
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 381 e-105
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 379 e-105
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 365 e-101
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 360 2e-99
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 357 2e-98
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 357 3e-98
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 350 2e-96
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 348 2e-95
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 348 2e-95
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 347 2e-95
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 347 2e-95
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 343 4e-94
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 341 2e-93
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 340 3e-93
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 334 2e-91
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 334 2e-91
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 308 2e-83
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 307 2e-83
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 293 4e-79
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 284 3e-76
gi|16753221 cadherin 22 precursor [Homo sapiens] 283 5e-76
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 279 7e-75
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 266 8e-71
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 266 8e-71
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 1686 bits (4366), Expect = 0.0
Identities = 829/829 (100%), Positives = 829/829 (100%)
Query: 1 MGLPRGPLASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPG 60
MGLPRGPLASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPG
Sbjct: 1 MGLPRGPLASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPG 60
Query: 61 QEPALFSTDNDDFTVRNGETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENG 120
QEPALFSTDNDDFTVRNGETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENG
Sbjct: 61 QEPALFSTDNDDFTVRNGETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENG 120
Query: 121 KGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAK 180
KGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAK
Sbjct: 121 KGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAK 180
Query: 181 YELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT 240
YELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT
Sbjct: 181 YELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT 240
Query: 241 DEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQA 300
DEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQA
Sbjct: 241 DEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQA 300
Query: 301 TDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSP 360
TDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSP
Sbjct: 301 TDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSP 360
Query: 361 AWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKL 420
AWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKL
Sbjct: 361 AWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKL 420
Query: 421 PTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILR 480
PTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILR
Sbjct: 421 PTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILR 480
Query: 481 DPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLID 540
DPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLID
Sbjct: 481 DPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLID 540
Query: 541 VNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGD 600
VNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGD
Sbjct: 541 VNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGD 600
Query: 601 TVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVL 660
TVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVL
Sbjct: 601 TVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVL 660
Query: 661 GAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHR 720
GAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHR
Sbjct: 661 GAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHR 720
Query: 721 GLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVF 780
GLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVF
Sbjct: 721 GLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVF 780
Query: 781 DYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
DYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD
Sbjct: 781 DYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 922 bits (2384), Expect = 0.0
Identities = 477/875 (54%), Positives = 594/875 (67%), Gaps = 56/875 (6%)
Query: 9 ASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKV-FMGCPGQEPALFS 67
A LLLLQV C EPC F T E G+ LG+V F C G++ +
Sbjct: 10 ALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYF 69
Query: 68 TDNDDFTVRNGETVQERRSLKERNP----------------------------------- 92
+ + F V + +R L+ NP
Sbjct: 70 SLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQ 129
Query: 93 ---------LKIFP-SKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIF 142
L FP S LRR KRDWV+ PIS PEN KGPFP+ L Q+KSNKD++ K+F
Sbjct: 130 ASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVF 189
Query: 143 YSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNIS 202
YSITG GAD+PP GVF +E+ETGWL + +PLDRE IA Y LF HAVS NG +VEDPM I
Sbjct: 190 YSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEIL 249
Query: 203 IIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEP 262
I VTDQND+KP+FTQ+ F+GSV+EG LPGTSVM+VTATD DD + TYN +AY+I SQ+P
Sbjct: 250 ITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDP 309
Query: 263 KDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDAN 322
+ P MFTI+R+TG ISV+++GLDRE P YTL +QA D+ G+G +TTA AV+ + D N
Sbjct: 310 ELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTN 369
Query: 323 DNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTH 382
DN P+F+P Y+ VPEN + L VTD DAPN+PAW A Y I+ DDG F +TT+
Sbjct: 370 DNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-NDDGGQFVVTTN 428
Query: 383 PESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVP 442
P +N GIL T KGLDFEAK Q+ L+V VTN PF + L TSTAT+ V V DVNEAP+FVP
Sbjct: 429 PVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVP 488
Query: 443 PSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTL 501
P K VEV E G+ + YTA++PD QKI+YRI RD A WL ++PD+G ++ L
Sbjct: 489 PEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAEL 548
Query: 502 DREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPV 561
DRED + V+N+ Y +++A DNGSP TGTGTLLL L DVND+ P+PEPR I C ++P
Sbjct: 549 DREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPK 608
Query: 562 RQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNE-EGDTVVLSLKKFLKQDTYDVHLS 620
QV+NI D DL P+TSPF A+LT + WT + N+ ++++L K L+ Y ++L
Sbjct: 609 PQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLK 668
Query: 621 LSDHGNKEQLTVIRATVCDCHGHVETC--PGPWKGGF----ILPVLGAVLALLFLLLVLL 674
L D+ NK+Q+T + +VCDC G C P + G IL +LG +LALL L+L+LL
Sbjct: 669 LMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLL 728
Query: 675 LLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDV 734
L +R++ +KEPLL PEDDTRDNV+YY EEGGGEEDQD+D++QLHRGL+ARPEV RNDV
Sbjct: 729 LFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVT-RNDV 787
Query: 735 APTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSS 794
APT++ P Y PRPANPDEIGNFI ENLKAA+TDPTAPPYD+LLVFDYEGSGS+AASLSS
Sbjct: 788 APTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSS 847
Query: 795 LTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
L SS SD+DQDYDYLNEWG+RFKKLADMYGGGEDD
Sbjct: 848 LNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 638 bits (1645), Expect = 0.0
Identities = 355/758 (46%), Positives = 471/758 (62%), Gaps = 36/758 (4%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
L+R KRDWV+ PI++PEN +GPFPQ L +++S++D++ + YS+TGPGAD PP G+F +
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIIN 213
Query: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
+G L + KPLDRE+IA++ L HAV NG VE+P++I I V D ND++P+F +
Sbjct: 214 PISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWN 273
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
G+V EG PGT VM VTA D DD NG++ Y I SQ P P MFTI+ TG I
Sbjct: 274 GTVPEGSKPGTYVMTVTAIDADDP-NALNGMLRYRIVSQAPSTPSPNMFTINNETGDIIT 332
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD---GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
+++GLDREKV +YTL IQATDM+G+ G + TA AV+ + D NDN P F + VP
Sbjct: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
Query: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
EN V V LTVTD D P++PAW A Y I GGD F I T P SN G++T K +DF
Sbjct: 393 ENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDF 452
Query: 399 EAKNQHTLYVEVTNEAPFVLKL---PTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
E L V N+ P + P STAT+ V V DVNE P F P K++ +EG+
Sbjct: 453 ETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHA 512
Query: 456 GEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIY 514
G + +TA+DPD+ Q I Y L DPA WL +DP +GQ+T + LDRE V+NNIY
Sbjct: 513 GTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPN-VKNNIY 571
Query: 515 EVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNIT--DKDL 572
LA DNG PP +GTGTL + L+D+ND+ P P++ C ++P +NIT D D+
Sbjct: 572 NATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETC-ETPDPNSINITALDYDI 630
Query: 573 SPHTSPFQAQLTDDSDIY---WTAEVNEEGDTVVLSLK-KFLKQDTYDVHLSLSDHGN-- 626
P+ PF L WT GD L+LK KFL+ Y+V + ++D GN
Sbjct: 631 DPNAGPFAFDLPLSPVTIKRNWTI-TRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPP 689
Query: 627 KEQLTVIRATVCDCHGH-----VETCPGPWKG-GFILPVLGAVLALLFLLLVLLLLVR-- 678
K ++++R VC C + V+ G G G I+ +L ++ LL L+L+ ++ ++
Sbjct: 690 KSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRR 749
Query: 679 -KKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEV-----VLRN 732
K+R+ K+ L+ PEDD RDN+ Y EEGGGEEDQDYD++QL + P+ + R
Sbjct: 750 DKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRM 809
Query: 733 DVAPTIIPTPMYRPRPA--NPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAA 790
D P I P Y R A +P +IG+FI E LKAA+ DPTAPPYD+LLVFDYEGSGS A
Sbjct: 810 DERP-IHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAG 868
Query: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGED 828
SLSSL SS+S +QDYDYLN+WG RFKKLADMYGGG+D
Sbjct: 869 SLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD 906
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 616 bits (1588), Expect = e-176
Identities = 344/762 (45%), Positives = 469/762 (61%), Gaps = 43/762 (5%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
LRR KRDWV+ PI+VPEN +GPFPQ+L +++S+KD D I YSITG GAD PP VF+++
Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSID 223
Query: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
+G + + +P+DREE A Y L HAV NG VE+P+++ I V D ND++P+F +
Sbjct: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYN 283
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
GSV EG PGT VM VTA D DD+ T NG+V Y I +Q P+ P MFTI+ TG I
Sbjct: 284 GSVDEGSKPGTYVMTVTANDADDST-TANGMVRYRIVTQTPQSPSQNMFTINSETGDIVT 342
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD---GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
+++GLDREKV +YT+ +QATDM+G+ G + TA A++ + D NDN P F + VP
Sbjct: 343 VAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVP 402
Query: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
EN V V LTV D D P+SP W A Y I+ GD HF++ T P +N+G++T K +D+
Sbjct: 403 ENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDY 462
Query: 399 EAKNQHTLYVEVTNEAPFVLKLP---TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
E L V V+N+AP + STA + + + D+NEAP F K++ ++EG+P
Sbjct: 463 ELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPP 522
Query: 456 GEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIY 514
G + ++A DPD+ Q + Y L DPA WL ++ +GQ+T LDRE + +NN+Y
Sbjct: 523 GTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRE-SLYTKNNVY 581
Query: 515 EVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNIT--DKDL 572
E LA DNG PP +GTGTL + LID+ND+ P P++ IC + P +NIT D D+
Sbjct: 582 EATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQIC-EKPNLNAINITAADADV 640
Query: 573 SPHTSPFQAQLTDDSDIY---WTAEVNEEGDTVVLSLK-KFLKQDTYDVHLSLSDHGNK- 627
P+ P+ +L WT GD LSL+ +L+ YDV + ++D GN
Sbjct: 641 DPNIGPYVFELPFVPAAVRKNWTI-TRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPP 699
Query: 628 -EQLTVIRATVCDC--HGHVETCPGPWKGGFILPVLGAVLALLFLLLVLLLLV------- 677
++I+ VC C +G T G GA++A+L +L+LL +V
Sbjct: 700 LSNTSIIKVKVCPCDDNGDCTTIGAVAAAGL---GTGAIVAILICILILLTMVLLFVMWM 756
Query: 678 ---RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHR-----GLEARPEVV 729
K+R K+ L+ PEDD RDN+ Y EEGGGEEDQDYD++QL + + ++ V
Sbjct: 757 KRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGV 816
Query: 730 LRNDVAPTIIPTPMY--RPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGS 787
R D P + P Y RP +P +IG+FI E L+AA+ DPTAPPYD+LLVFDYEGSGS
Sbjct: 817 RRVDERP-VGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGS 875
Query: 788 DAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
A S+SSL SS+S DQDYDYLN+WG RFKKLADMYGGGE+D
Sbjct: 876 TAGSVSSLNSSSSG-DQDYDYLNDWGPRFKKLADMYGGGEED 916
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 497 bits (1279), Expect = e-140
Identities = 311/766 (40%), Positives = 424/766 (55%), Gaps = 41/766 (5%)
Query: 90 RNPLKIFPSKRI--LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITG 147
R P ++P +R L R +R WV+ PISV EN K P L Q+KS+K + + YSI G
Sbjct: 26 RRPTTLYPWRRAPALSRVRRAWVIPPISVSENHKR-LPYPLVQIKSDKQQLGSVIYSIQG 84
Query: 148 PGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTD 207
PG D P GVF+++K TG + LN LDRE+ ++ L A+ G+++EDP ++ I+V D
Sbjct: 85 PGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVD 144
Query: 208 QNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHD 267
QND++P F Q+ F G VLEG +PGT V + ATD DD T N + +SI Q +
Sbjct: 145 QNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDADDP-ETDNAALRFSILQQGSPE--- 200
Query: 268 LMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPM 327
+F+I TG I + GLDRE V Y LT+Q DM GDG T TA A++ + D NDNAP
Sbjct: 201 -LFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPE 259
Query: 328 FDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQ 387
F ++ E G +V RL V D D P SP W A + I+ GD FTI T P++N+
Sbjct: 260 FTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNE 319
Query: 388 GILTTRKGLDFEAKNQHTLYVEVTNEAPF---VLKLPTSTATIVVHVEDVNEAPVFVPPS 444
G+L+ K LD+E+ + L V V NEAP L+ A + VHV+D NE PVF
Sbjct: 320 GVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENP 379
Query: 445 KVVEVQEGIPTGEPVCVYTAEDPDKEN-QKISYRILRDPAGWLAMDPDSGQVTAVGTLDR 503
+ EG P G V ++A DPD E Q++SY DP WL +D +G++ L
Sbjct: 380 LRTSLAEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLS- 438
Query: 504 EDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPV---PEPRQITICNQSP 560
F++ Y +VLA D+ S P T TGTL + +++VNDH PV P P +
Sbjct: 439 PASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQG 498
Query: 561 VRQVLNITDKDLSPHTSPFQAQLT---DDSDIYWT-AEVNEEGDTVVLSLKKFLKQDTYD 616
+L TD+DL PH +PF QL+ + W+ ++VN L + + + +
Sbjct: 499 PGLLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNV--SHARLRPRHQVPEGLHR 556
Query: 617 VHLSLSDHGN--KEQLTVIRATVCDCHGHVETCPG-----PWKGGFILPVLGAVLALLFL 669
+ L L D G +++ + TVC C PG G L L VLA L
Sbjct: 557 LSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALL 616
Query: 670 LLVLLLLVR------KKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHR-- 720
LLVL+LLV K+ + K L P+DD RDNV Y E+GGGEEDQD YDI+QL
Sbjct: 617 LLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPT 676
Query: 721 --GLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLL 778
L P + R+ + P P R P +P +I +FI + L+AA++DP+ PPYDT L
Sbjct: 677 ALSLPLGPPPLRRDAPQGRLHPQPP-RVLPTSPLDIADFINDGLEAADSDPSVPPYDTAL 735
Query: 779 VFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYG 824
++DYEG GS A +LSS+ SS D+DQDYDYL +WG RF +LADMYG
Sbjct: 736 IYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 381 bits (978), Expect = e-105
Identities = 271/760 (35%), Positives = 390/760 (51%), Gaps = 57/760 (7%)
Query: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVEK 162
R KR WV V E G P + +L S+ D+ D I Y ++G GA S +F +++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IFIIDE 99
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVSE-NGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
TG + K LDREE A Y L A+ VE I + D ND++PKF +
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVPE 339
+DRE +Y L IQA DM G G + T V + D NDN P F + Y+ +VPE
Sbjct: 214 ALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPE 273
Query: 340 NA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
+ V V R+ D D + Y I+ GD F I+ E+ +GI+T +K LDF
Sbjct: 274 SLPVASVVARIKAADADIGANAEME--YKIVDGDGLGIFKISVDKETQEGIITIQKELDF 331
Query: 399 EAKNQHTLYVEVTNEA--PFVLKLP--TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIP 454
EAK +TL +E N+ P L L + T T+ + VEDV+E PVF P +EV E
Sbjct: 332 EAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQ 391
Query: 455 TGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQFVRNN 512
G + A DPD N + Y I R D + +D +SG +T +LDRE N
Sbjct: 392 VGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-----NA 446
Query: 513 IYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVL---NIT 568
I+ + VLAM++ +P G G + +T++D+ND+ P + T+C + QV+ +
Sbjct: 447 IHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAV 506
Query: 569 DKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDTVVLSLKKFLK---QDTYDVHLSLSD 623
DKD + F LT D+ + ++ + N++ +L+ + + Q Y + + + D
Sbjct: 507 DKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVD 566
Query: 624 HGNKE----QLTVIRATVCDCHGHVETC-------PGPWKGGFILPVLGAVLALLFLLLV 672
G+ IR CD G +TC P G ++ +L VL LL L+L+
Sbjct: 567 SGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILL 626
Query: 673 LLLLVRKKRKIKEPLLLPED-DTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVVL 730
++ + R+K KEPL+ E+ D R+N+ Y +EGGGEED + +D+ L R L +
Sbjct: 627 IVTMRRRK---KEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAAL-RNLNVIRDTKT 682
Query: 731 RNDVAPTI--IPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSD 788
R DV P I + P ++ P N FI E LK A+ DP APPYD+L + +EG+GS
Sbjct: 683 RRDVTPEIQFLSRPAFKSIPDNVI-FREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSV 741
Query: 789 AASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGED 828
A SLSSL S +S+ DQ+YDYL++WG RFK+LADMYG G++
Sbjct: 742 AESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 381 bits (978), Expect = e-105
Identities = 271/760 (35%), Positives = 390/760 (51%), Gaps = 57/760 (7%)
Query: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVEK 162
R KR WV V E G P + +L S+ D+ D I Y ++G GA S +F +++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IFIIDE 99
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVSE-NGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
TG + K LDREE A Y L A+ VE I + D ND++PKF +
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVPE 339
+DRE +Y L IQA DM G G + T V + D NDN P F + Y+ +VPE
Sbjct: 214 ALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPE 273
Query: 340 NA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
+ V V R+ D D + Y I+ GD F I+ E+ +GI+T +K LDF
Sbjct: 274 SLPVASVVARIKAADADIGANAEME--YKIVDGDGLGIFKISVDKETQEGIITIQKELDF 331
Query: 399 EAKNQHTLYVEVTNEA--PFVLKLP--TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIP 454
EAK +TL +E N+ P L L + T T+ + VEDV+E PVF P +EV E
Sbjct: 332 EAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQ 391
Query: 455 TGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQFVRNN 512
G + A DPD N + Y I R D + +D +SG +T +LDRE N
Sbjct: 392 VGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-----NA 446
Query: 513 IYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVL---NIT 568
I+ + VLAM++ +P G G + +T++D+ND+ P + T+C + QV+ +
Sbjct: 447 IHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAV 506
Query: 569 DKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDTVVLSLKKFLK---QDTYDVHLSLSD 623
DKD + F LT D+ + ++ + N++ +L+ + + Q Y + + + D
Sbjct: 507 DKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVD 566
Query: 624 HGNKE----QLTVIRATVCDCHGHVETC-------PGPWKGGFILPVLGAVLALLFLLLV 672
G+ IR CD G +TC P G ++ +L VL LL L+L+
Sbjct: 567 SGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILL 626
Query: 673 LLLLVRKKRKIKEPLLLPED-DTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVVL 730
++ + R+K KEPL+ E+ D R+N+ Y +EGGGEED + +D+ L R L +
Sbjct: 627 IVTMRRRK---KEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAAL-RNLNVIRDTKT 682
Query: 731 RNDVAPTI--IPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSD 788
R DV P I + P ++ P N FI E LK A+ DP APPYD+L + +EG+GS
Sbjct: 683 RRDVTPEIQFLSRPAFKSIPDNVI-FREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSV 741
Query: 789 AASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGED 828
A SLSSL S +S+ DQ+YDYL++WG RFK+LADMYG G++
Sbjct: 742 AESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 379 bits (973), Expect = e-105
Identities = 258/719 (35%), Positives = 375/719 (52%), Gaps = 57/719 (7%)
Query: 4 PRGPLASLLLL-QVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPGQE 62
PR PL +LL QV L A C F++ + E L F C G +
Sbjct: 3 PRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGND 62
Query: 63 PALFSTDNDDFTV---------RNGETVQERRSLKERNP-------LKIFPSKRI----- 101
+ + F V RN V + + R P L I K I
Sbjct: 63 KLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQ 122
Query: 102 ----------LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGAD 151
+ R KR VV+PI +PEN + PFP+ + ++ + DR + + +TG G D
Sbjct: 123 DIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDS-DRPERSKFRLTGKGVD 181
Query: 152 SPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDH 211
P+G+F + + TG + + + LDRE IA Y+LF NG ++E P+ + +IV DQND+
Sbjct: 182 QEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDN 241
Query: 212 KPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFT 271
+P F + + G V+EG GT+VM++TA D DD T N ++ Y+I Q P P MF
Sbjct: 242 RPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPA-TDNALLRYNIRQQTPDKPSPNMFY 300
Query: 272 IHRSTGTISVISSG--LDREKV--PEYTLTIQATDMDG--DGSTTTAVAVVEILDANDNA 325
I G I + S LDRE + P+Y L I+A DM G G T TA A + I D ND++
Sbjct: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
Query: 326 PMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPES 385
P F ++++A V E AVG + LTV D D P + AWRA Y I+ G+ G F I T+P++
Sbjct: 361 PKFTKKEFQATVEEGAVG-VIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQT 419
Query: 386 NQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKL---PTSTATIVVHVEDVNEAPVFVP 442
N+G+L+ K LD+E HTL ++V NE P V + P+STAT+ + V DVNE PVF P
Sbjct: 420 NEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYP 479
Query: 443 PSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTL 501
+V QE + G + A DPD ++Q I Y + +DPAGWL ++P +G V L
Sbjct: 480 DPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVL 539
Query: 502 DREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPV 561
DRE FV N++Y + LA+D+G+PP TGTGTLL+TL DVND+ P P +C+ +
Sbjct: 540 DRE-SPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKN 598
Query: 562 RQV--LNITDKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDT-VVLSLKKFLKQDTYD 616
V L +DKDL P+T PF+ ++ + D W ++++ +T ++SL + L + Y+
Sbjct: 599 LSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVW--KISKINNTHALVSLLQNLNKANYN 656
Query: 617 VHLSLSDHGN--KEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLGAVLALLFLLLVL 673
+ + ++D G +T +R VC C C F LP +L LF L L
Sbjct: 657 LPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLP--SVLLLSLFSLACL 713
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 365 bits (937), Expect = e-101
Identities = 262/766 (34%), Positives = 394/766 (51%), Gaps = 56/766 (7%)
Query: 98 SKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEG 156
SK L R KR W+ + E G Q + +L S++DR D + Y ++G GA
Sbjct: 44 SKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGD---- 99
Query: 157 VFAVEKETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDPMNISIIVTDQNDHKPKF 215
+F + + TG + K LDREE Y L A++ G VE I + D ND++P F
Sbjct: 100 LFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIF 159
Query: 216 TQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRS 275
T++ + +V E GT V+QVTATD DD Y + V YSI +P F++
Sbjct: 160 TKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP------YFSVESE 213
Query: 276 TGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKY 333
TG I +DRE +Y + IQA DM G G + T + + D NDN P F Y
Sbjct: 214 TGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTY 273
Query: 334 EAHVPENAV-GHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTT 392
+ PE++ G + R+ +D D + Y I G+ D F + T E+ +GI+T
Sbjct: 274 QFKTPESSPPGTPIGRIKASDADVGENA--EIEYSITDGEGLDMFDVITDQETQEGIITV 331
Query: 393 RKGLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVE 448
+K LDFE K +TL VE +N E F+ P +AT+ + VEDV+E PVF + +++
Sbjct: 332 KKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQ 391
Query: 449 VQEGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDE 506
++E + TA+DPD + Y + R D +D +G + LDRE
Sbjct: 392 IREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETL 451
Query: 507 QFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQV- 564
+ + + V+A + +P + L + ++DVND+ P E + +C ++ Q+
Sbjct: 452 LW-----HNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLI 506
Query: 565 --LNITDKD--LSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQ---DTYDV 617
L+ DKD S H F S +T + N++ +L+ K + TY +
Sbjct: 507 QTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLL 566
Query: 618 HLSLSDHGNKEQLTV----IRATVCDCHGHVETCPGPWKGGFILPV---LGAVLALLFLL 670
+ +SD+ Q + +R CD HG++++C I P GA++A+L +
Sbjct: 567 PVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAE---ALIHPTGLSTGALVAILLCI 623
Query: 671 LVLLLLV------RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEED-QDYDITQLHRGLE 723
++LL+ V R++RK KEPL++ ++D RDN+ Y +EGGGEED Q +DI L R E
Sbjct: 624 VILLVTVVLFAALRRQRK-KEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTL-RNPE 681
Query: 724 ARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYE 783
A + LR D+ P + P P + ++ +FI + LK +TDPTAPPYD+L + YE
Sbjct: 682 AIEDNKLRRDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYE 741
Query: 784 GSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
G+GS A SLSSL S +D DQDYDYL++WG RFKKLADMYGG + D
Sbjct: 742 GTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADMYGGVDSD 787
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 360 bits (925), Expect = 2e-99
Identities = 263/764 (34%), Positives = 396/764 (51%), Gaps = 56/764 (7%)
Query: 100 RILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVF 158
++LRR KR W+ + E G Q + +L +++D+ D + Y +TG GA S +F
Sbjct: 46 KMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LF 101
Query: 159 AVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFTQ 217
+++ TG + K LDREE + Y L A+ + G VE I + D ND++PKFT+
Sbjct: 102 VIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK 161
Query: 218 DTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTG 277
D + SV E GTSV+QVTATD DDA Y + V YSI +P F++ +G
Sbjct: 162 DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESG 215
Query: 278 TISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEA 335
I + RE +Y + IQA DM G G + T + + D N+N P F Y+
Sbjct: 216 IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQF 275
Query: 336 HVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRK 394
+ PE+ +G + R+ D D + Y I GD D F + T ++ +GI+T ++
Sbjct: 276 NSPESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQ 333
Query: 395 GLDFEAKNQHTLYVEVTNEAP---FVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQ 450
LDFE + +TL V+ +N P F+ P TA + + VED++E PVF S ++EV
Sbjct: 334 NLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVD 393
Query: 451 EGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQF 508
E + G + TA DPD N I Y + R D + ++G + + LDRE +
Sbjct: 394 EDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW 453
Query: 509 VRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQIT-IC-NQSPVR--QV 564
+ + V A + +P + + + ++D+NDH P T +C N P + Q
Sbjct: 454 -----HNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQT 508
Query: 565 LNITDKDLSPHTSPFQAQLTDDSDIY--WTAEVNEEGDTVVLSLKKFL---KQDTYDVHL 619
+++ DKD P F + + + +T N++ +++ K K TY + +
Sbjct: 509 VSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
Query: 620 SLSDHGNKEQLTV----IRATVCDCHGHVETCPGPWKGGFILPV---LGAVLALLFLLLV 672
+ D+ Q + IR CD G++++C IL GA++A+L +L+
Sbjct: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAE---ALILSAGLSTGALVAILLCVLI 625
Query: 673 LLLLV-----RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEED-QDYDITQLHRGLEARP 726
LL+LV K+++ KEPL++ +DD RDN+ Y +EGGGEED Q +DI L R EAR
Sbjct: 626 LLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTL-RNPEARE 684
Query: 727 EVVLRNDVAP-TIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGS 785
+ LR DV P TI P N D + +FI LK + DP+APPYD+L + YEG+
Sbjct: 685 DSKLRRDVMPETIFQIRRTVPLWENID-VQDFIHRRLKENDADPSAPPYDSLATYAYEGN 743
Query: 786 GSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
S A SLSSL S +D +QDYDYL++WG RFKKLADMYGG + D
Sbjct: 744 DSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 357 bits (917), Expect = 2e-98
Identities = 260/759 (34%), Positives = 385/759 (50%), Gaps = 54/759 (7%)
Query: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVEK 162
R KR WV V E GP PQ + +L SN D+ D + Y +TG GA + +F ++
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISII-VTDQNDHKPKFTQDTFR 221
TG + K LDRE+ Y L A+ +P + II V D ND+ PKFT +
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
+V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD-----GSTTTAVAVVEILDANDNAPMFDPQKYEAH 336
+DRE Y++ IQA DM G GSTT + + D NDN P F + Y+ +
Sbjct: 220 ALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLT---DVNDNPPRFPQKHYQLY 276
Query: 337 VPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKG 395
VPE+A VG V ++ D D ++ TY I+ GD F+I+T E+ +GIL+ +K
Sbjct: 277 VPESAQVGSAVGKIKANDADTGSNADM--TYSIINGDGMGIFSISTDKETREGILSLKKP 334
Query: 396 LDFEAKNQHTLYVEVTN---EAPFVLKLPTSTATIV-VHVEDVNEAPVFVPPSKVVEVQE 451
L++E K +TL +E N + F P AT++ + V DV+E P+F PS ++EV E
Sbjct: 335 LNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYE 394
Query: 452 GIPTGEPVCVYTAEDPDKENQKISYRILRDPAG--WLAMDPDSGQVTAVGTLDREDEQFV 509
G V A+DPD N + Y I + + +D ++G + LDRE+ +
Sbjct: 395 NAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPW- 453
Query: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVLNI- 567
Y + V A + +P T+ + ++DVND+ P + I +C S QV++
Sbjct: 454 ----YNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTI 509
Query: 568 --TDKDLSPHTSPFQAQLTDDSDIY--WTAEVNEEGDTVVLSLKKFLK---QDTYDVHLS 620
TDKD + F L + + +T + NE+ +L+ ++ QD Y + +
Sbjct: 510 SATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIM 569
Query: 621 LSDHG----NKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLGAVLALLFLLLVLL-- 674
+SD G + IR C+ G V TC GA++A+L +L+LL
Sbjct: 570 ISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAI 629
Query: 675 --LLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVVLR 731
L + +R KEPL++ E+D R+NV Y +EGGGEED + +DIT L R A E+ R
Sbjct: 630 VVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITAL-RNPSAAEELKYR 688
Query: 732 NDVAPTIIPTPMYRPRPANPD-EIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAA 790
D+ P + TP ++ ++ FI + L A+ DP+ PPYD+L + YEG S+A
Sbjct: 689 RDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAG 748
Query: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
S+SSL S+ + DQDY YL +WG FKKLA++YG E +
Sbjct: 749 SISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESE 787
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 357 bits (916), Expect = 3e-98
Identities = 259/761 (34%), Positives = 385/761 (50%), Gaps = 55/761 (7%)
Query: 100 RILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVF 158
++L+R KR WV V E GP P + +L S+ D D I Y ++G GA + +F
Sbjct: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IF 101
Query: 159 AVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFTQ 217
++ ++G + K LDREE A+Y L AV + +E P + V D ND+ P+F
Sbjct: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
Query: 218 DTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTG 277
+T+ +V E GTSV+QVTA+D DD Y + + YSI +P F++ TG
Sbjct: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTG 215
Query: 278 TISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEA 335
I +DRE EY + IQA DM G G + T + + D NDN P F Y+
Sbjct: 216 IIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
Query: 336 HVPENAV-GHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRK 394
V E AV G EV R+ D D + TY I+ GD + F ITT E+ +G++ +K
Sbjct: 276 SVSEAAVPGEEVGRVKAKDPDIGENGL--VTYNIVDGDGMESFEITTDYETQEGVIKLKK 333
Query: 395 GLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQ 450
+DFE K ++L VE N + F+ P T T+ + VED +E P+F+ PS + EVQ
Sbjct: 334 PVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQ 393
Query: 451 EGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQF 508
E G V A+DPD N I Y I R D + ++P+ G + LDRE+ +
Sbjct: 394 ENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAW 453
Query: 509 VRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVLN- 566
+ + V A + + + + ++DVND+ P P + IC + + N
Sbjct: 454 LN-----ITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQ 508
Query: 567 ------ITDKDLSPHTSPFQAQLTDD--SDIYWTAEVNEEGDTVVLSLKKFL---KQDTY 615
DKD + + F L + + +T N + V + + KQD Y
Sbjct: 509 PIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLY 568
Query: 616 DVHLSLSDHG----NKEQLTVIRATVCDCHGHVETCPGP---WKGGFILPVLGAVLALLF 668
+ + +SD G + I+ CD +G + +C G L A+LA +
Sbjct: 569 LLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIV 628
Query: 669 LLLVLLLL-VRKKRKIKEPLLL-PEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEAR 725
+LLV+++L V +R+ KEPL++ E+D R+N+ Y +EGGGEED + +DI L +
Sbjct: 629 ILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP-DGI 687
Query: 726 PEVVLRNDVAPTI--IPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYE 783
+ R D+ P +P P RP P N ++ +FI ++ A+ DPTAPPYD++ ++ YE
Sbjct: 688 NGFIPRKDIKPEYQYMPRPGLRPAP-NSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYE 746
Query: 784 GSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYG 824
G GS A SLSSL S+ +D D DYDYL WG RFKKLAD+YG
Sbjct: 747 GRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYG 787
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 350 bits (899), Expect = 2e-96
Identities = 259/780 (33%), Positives = 396/780 (50%), Gaps = 56/780 (7%)
Query: 81 VQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DT 139
V ++R L R P +IL R KR W+ + E G Q + +L S++D+ D
Sbjct: 31 VPQQRILSSRVPRS---DGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDG 87
Query: 140 KIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPM 199
+ Y ++G GA + +F ++++TG + + +DREE A Y L A++ +P
Sbjct: 88 SLKYILSGDGAGT----LFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPE 143
Query: 200 NISII-VTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH 258
+ +I + D ND++P F ++ + SV E + GTSV+QVTATD DD Y + V YSI
Sbjct: 144 SEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSIL 203
Query: 259 SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVV 316
+P F++ TG I ++RE +Y + IQA DM G G + T +
Sbjct: 204 QGQP------YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNI 257
Query: 317 EILDANDNAPMFDPQKYEAHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGD 375
+ D NDN P F V E++ VG + + TD D + Y I+ GD D
Sbjct: 258 TLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTD 315
Query: 376 HFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTN---EAPFVLKLPTSTATIV-VHV 431
F I T ++ +GI+T +K LD+E++ +TL VE N + F P TIV + +
Sbjct: 316 MFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISI 375
Query: 432 EDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMD 489
EDV+E PVF S + EV E I G + A DPD + I + + R D +
Sbjct: 376 EDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIH 435
Query: 490 PDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPE 549
+G + LDRE Q+ + + V+A + +P T + + ++DVND+ P
Sbjct: 436 SGNGSLYTSKPLDRELSQW-----HNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFA 490
Query: 550 PRQIT-ICNQS---PVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLS 605
T +C + + Q ++ DKD F L + + T + NE+ +L+
Sbjct: 491 VFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNF-TVQDNEDNTARILT 549
Query: 606 LKKFLKQ---DTYDVHLSLSDHGNKEQLTV----IRATVCDCHGHVETCPGPWKGGFILP 658
K + TY + + +SD+ Q + IR CD G++++C +LP
Sbjct: 550 RKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAE---ALLLP 606
Query: 659 V---LGAVLALLFLLLVLLLLV-----RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEED 710
GA++A+L +++LL++V K+++ KEPL+L ++D RDN+ Y +EGGGEED
Sbjct: 607 AGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEED 666
Query: 711 -QDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDP 769
Q +DI L R A E LR D+ P + P P + ++ +FI E LK + DP
Sbjct: 667 TQAFDIGTL-RNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDP 725
Query: 770 TAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
TAPPYD+L + YEG+ S A SLSSL S ++ DQ+YDYL EWG RF KLA+MYGGGE D
Sbjct: 726 TAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 348 bits (892), Expect = 2e-95
Identities = 226/669 (33%), Positives = 347/669 (51%), Gaps = 30/669 (4%)
Query: 65 LFSTDNDDFTVRNGETVQERRS-----LKERNPL--KIFPSKRILRRHKRDWVVAPISVP 117
L S++ FT+ T + + L+ + + K +++LRR KR W P S+
Sbjct: 86 LLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSML 145
Query: 118 ENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREE 177
EN GPFP L Q++S+ ++ I+YSI GPG D P +F VE++TG L +P+DRE+
Sbjct: 146 ENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQ 205
Query: 178 IAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQV 237
+E+ A + +G + E P+ + I + D+ND+ P FT++T+ ++ E GT+V QV
Sbjct: 206 YESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQV 265
Query: 238 TATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLT 297
ATD+D+ T + + YSI Q P P +F++H +TG I+ SS LDRE + +Y L
Sbjct: 266 CATDKDEP-DTMHTRLKYSIIGQVPPSP--TLFSMHPTTGVITTTSSQLDRELIDKYQLK 322
Query: 298 IQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLD 355
I+ DMDG G TT+ ++ I D ND+ P F Y V EN V E+ R+TV D D
Sbjct: 323 IKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKD 382
Query: 356 APNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAP 415
N+ WRA Y I+ G++ +F I T ++N+G+L K L++E K Q L + V NEAP
Sbjct: 383 LVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAP 442
Query: 416 FVL----KLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KE 470
F + STAT+ V+VED +E P PP + V ++E G Y A DP+ +
Sbjct: 443 FSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRS 502
Query: 471 NQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTG 530
+ I Y+ L DP GW+ +D ++G + +LDRE E ++N IY + VLA D G T
Sbjct: 503 SSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET-IKNGIYNITVLASDQGG--RTC 559
Query: 531 TGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQL-TDDSDI 589
TGTL + L DVND+ P + + IC + + D D H PF L + S++
Sbjct: 560 TGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEV 619
Query: 590 YWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETC- 647
+ DT LS + +Y V +++ D +T + T+CDC +
Sbjct: 620 QRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTH 679
Query: 648 ---PGPWKGGFIL---PVLGAVLALLFLLLVLLLLV-RKKRKIKEPLLLPEDDTRDNVFY 700
P GG L +L +L + L +L LV K+P ++P+D + N+
Sbjct: 680 RVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIV 739
Query: 701 YGEEGGGEE 709
E G++
Sbjct: 740 SNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 348 bits (892), Expect = 2e-95
Identities = 226/669 (33%), Positives = 347/669 (51%), Gaps = 30/669 (4%)
Query: 65 LFSTDNDDFTVRNGETVQERRS-----LKERNPL--KIFPSKRILRRHKRDWVVAPISVP 117
L S++ FT+ T + + L+ + + K +++LRR KR W P S+
Sbjct: 86 LLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSML 145
Query: 118 ENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREE 177
EN GPFP L Q++S+ ++ I+YSI GPG D P +F VE++TG L +P+DRE+
Sbjct: 146 ENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQ 205
Query: 178 IAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQV 237
+E+ A + +G + E P+ + I + D+ND+ P FT++T+ ++ E GT+V QV
Sbjct: 206 YESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQV 265
Query: 238 TATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLT 297
ATD+D+ T + + YSI Q P P +F++H +TG I+ SS LDRE + +Y L
Sbjct: 266 CATDKDEP-DTMHTRLKYSIIGQVPPSP--TLFSMHPTTGVITTTSSQLDRELIDKYQLK 322
Query: 298 IQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLD 355
I+ DMDG G TT+ ++ I D ND+ P F Y V EN V E+ R+TV D D
Sbjct: 323 IKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKD 382
Query: 356 APNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAP 415
N+ WRA Y I+ G++ +F I T ++N+G+L K L++E K Q L + V NEAP
Sbjct: 383 LVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAP 442
Query: 416 FVL----KLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KE 470
F + STAT+ V+VED +E P PP + V ++E G Y A DP+ +
Sbjct: 443 FSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRS 502
Query: 471 NQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTG 530
+ I Y+ L DP GW+ +D ++G + +LDRE E ++N IY + VLA D G T
Sbjct: 503 SSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET-IKNGIYNITVLASDQGG--RTC 559
Query: 531 TGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQL-TDDSDI 589
TGTL + L DVND+ P + + IC + + D D H PF L + S++
Sbjct: 560 TGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEV 619
Query: 590 YWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETC- 647
+ DT LS + +Y V +++ D +T + T+CDC +
Sbjct: 620 QRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTH 679
Query: 648 ---PGPWKGGFIL---PVLGAVLALLFLLLVLLLLV-RKKRKIKEPLLLPEDDTRDNVFY 700
P GG L +L +L + L +L LV K+P ++P+D + N+
Sbjct: 680 RVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIV 739
Query: 701 YGEEGGGEE 709
E G++
Sbjct: 740 SNTEAPGDD 748
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 347 bits (891), Expect = 2e-95
Identities = 213/621 (34%), Positives = 325/621 (52%), Gaps = 18/621 (2%)
Query: 101 ILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAV 160
+LRR KR W P S+ EN GPFP L Q++S+ ++ +FYSI+G G D P +F +
Sbjct: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYI 188
Query: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTF 220
E++TG L +P+DREE ++L +A + +G S + P+ + I V D+ND+ P FT+ +
Sbjct: 189 ERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
Query: 221 RGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTIS 280
VLE PGT+V V ATD D+ T + + YSI Q P+ P +F++H STG I+
Sbjct: 249 NFEVLESSRPGTTVGVVCATDRDEP-DTMHTRLKYSILQQTPRSPG--LFSVHPSTGVIT 305
Query: 281 VISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
+S LDRE V +Y+L ++ DMDG G T+ ++ + D+NDNAP F YEA V
Sbjct: 306 TVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVE 365
Query: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
ENA E+ R+ + D D N+ WR + I+ G++ HF I+T E+N+G+L+ K L++
Sbjct: 366 ENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNY 425
Query: 399 EAKNQHTLYVEVTNEAPFVLKLPTST----ATIVVHVEDVNEAPVFVPPSKVVEVQEGIP 454
E Q L + V NEAPF +P T A + VHV D++E P P ++ V ++E +
Sbjct: 426 EENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLA 485
Query: 455 TGEPVCVYTAEDPDKEN-QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNI 513
G + Y A DP+ N + Y+ L DP GW+ +D SG + LDRE E +N +
Sbjct: 486 VGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET-PKNEL 544
Query: 514 YEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLS 573
Y + VLA+D + TGTL + + DVND+ P + IC + D D
Sbjct: 545 YNITVLAIDKDD--RSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEP 602
Query: 574 PHTSPFQAQLTDDS-DIYWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLT 631
H +PF L + S +I + + DT LS +K Y + +++ D +
Sbjct: 603 VHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATK 662
Query: 632 VIRATVCDCHGHVETCPGPWKGGFIL---PVLGAVLALLFLLLVLLLLVRKKRKIKEPLL 688
++R +C+C + G IL +L +L + L VLL LV +
Sbjct: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
Query: 689 LPEDDTRDNVFYYGEEGGGEE 709
PED + N+ E G++
Sbjct: 723 FPEDLAQQNLIISNTEAPGDD 743
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 347 bits (891), Expect = 2e-95
Identities = 213/621 (34%), Positives = 325/621 (52%), Gaps = 18/621 (2%)
Query: 101 ILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAV 160
+LRR KR W P S+ EN GPFP L Q++S+ ++ +FYSI+G G D P +F +
Sbjct: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYI 188
Query: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTF 220
E++TG L +P+DREE ++L +A + +G S + P+ + I V D+ND+ P FT+ +
Sbjct: 189 ERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
Query: 221 RGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTIS 280
VLE PGT+V V ATD D+ T + + YSI Q P+ P +F++H STG I+
Sbjct: 249 NFEVLESSRPGTTVGVVCATDRDEP-DTMHTRLKYSILQQTPRSPG--LFSVHPSTGVIT 305
Query: 281 VISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
+S LDRE V +Y+L ++ DMDG G T+ ++ + D+NDNAP F YEA V
Sbjct: 306 TVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVE 365
Query: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
ENA E+ R+ + D D N+ WR + I+ G++ HF I+T E+N+G+L+ K L++
Sbjct: 366 ENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNY 425
Query: 399 EAKNQHTLYVEVTNEAPFVLKLPTST----ATIVVHVEDVNEAPVFVPPSKVVEVQEGIP 454
E Q L + V NEAPF +P T A + VHV D++E P P ++ V ++E +
Sbjct: 426 EENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLA 485
Query: 455 TGEPVCVYTAEDPDKEN-QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNI 513
G + Y A DP+ N + Y+ L DP GW+ +D SG + LDRE E +N +
Sbjct: 486 VGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET-PKNEL 544
Query: 514 YEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLS 573
Y + VLA+D + TGTL + + DVND+ P + IC + D D
Sbjct: 545 YNITVLAIDKDD--RSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEP 602
Query: 574 PHTSPFQAQLTDDS-DIYWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLT 631
H +PF L + S +I + + DT LS +K Y + +++ D +
Sbjct: 603 VHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATK 662
Query: 632 VIRATVCDCHGHVETCPGPWKGGFIL---PVLGAVLALLFLLLVLLLLVRKKRKIKEPLL 688
++R +C+C + G IL +L +L + L VLL LV +
Sbjct: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
Query: 689 LPEDDTRDNVFYYGEEGGGEE 709
PED + N+ E G++
Sbjct: 723 FPEDLAQQNLIISNTEAPGDD 743
Score = 32.0 bits (71), Expect = 2.4
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 772 PPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLAD 821
P D +L ++YEG GS A S+ S ++ D+LN +F LA+
Sbjct: 844 PSQDYVLTYNYEGRGSPAGSVG--CCSEKQEEDGLDFLNNLEPKFITLAE 891
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 343 bits (880), Expect = 4e-94
Identities = 259/766 (33%), Positives = 387/766 (50%), Gaps = 57/766 (7%)
Query: 99 KRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTK-IFYSITGPGADSPPEGV 157
+RIL R KR WV + V E GP P + +L ++ D +K I Y ++G GA + +
Sbjct: 53 QRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGT----I 108
Query: 158 FAVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFT 216
F + TG + K LDREE A+Y L AV E +E P I V D ND+ P+F
Sbjct: 109 FQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFL 168
Query: 217 QDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRST 276
+ +V E + GTSV VTATD DD +Y + + YSI +P F+I T
Sbjct: 169 NGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP------YFSIEPET 222
Query: 277 GTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYE 334
I +DRE EY + IQA DM G G + T V + D NDN P F Y
Sbjct: 223 AIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYH 282
Query: 335 AHVPENAV-GHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTR 393
VPE+ V G + R+ D D + +++Y I+ GD F IT+ ++ GI+ R
Sbjct: 283 FSVPEDVVLGTAIGRVKANDQDIGENA--QSSYDIIDGDGTALFEITSDAQAQDGIIRLR 340
Query: 394 KGLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEV 449
K LDFE K +TL VE N + F + P TAT+ + VED +E PVF P+ ++EV
Sbjct: 341 KPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEV 400
Query: 450 QEGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQ 507
E + TA DPD + I + I R D ++ D G++T LDRE
Sbjct: 401 HENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSV 460
Query: 508 FVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP--VPEPRQITICNQSP--VRQ 563
+ + + ++A + + + + ++DVND+ P E N P V Q
Sbjct: 461 W-----HNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQ 515
Query: 564 VLNITDKDLSPHTSPFQAQLTDD--SDIYWTAEVNEEGDTVVLSLKKFL---KQDTYDVH 618
++ DKD + F L + ++ +T + NE+ +L+ KQ+ Y +
Sbjct: 516 TVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLP 575
Query: 619 LSLSDHGNK--EQLTVIRATVCDCH--GHVETCPGPWKGGFILPV---LGAVLALL---- 667
+ +SD GN + + VC C G V++C ++LP+ +GA++A+L
Sbjct: 576 IIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVE---AYVLPIGLSMGALIAILACII 632
Query: 668 FLLLVLLLLVRKKRKIKEPLLLPED-DTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEAR 725
LL++++L V +R EPL++ +D D R+N+ Y +EGGGEED + +DI L +
Sbjct: 633 LLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNP-DGI 691
Query: 726 PEVVLRNDVAPTI--IPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYE 783
+ R D+ P + +P P P N ++ FI L A+ DPTAPPYD++ ++ YE
Sbjct: 692 NGFLPRKDIKPDLQFMPRQGLAPVP-NGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYE 750
Query: 784 GSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
G GS A SLSSL S+ SD DQ++DYL++WG RFK+L ++Y GE D
Sbjct: 751 GRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESD 796
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 341 bits (874), Expect = 2e-93
Identities = 255/785 (32%), Positives = 386/785 (49%), Gaps = 65/785 (8%)
Query: 82 QERRSLKERNPLKIFPSKRI-LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DT 139
Q+ + + R + P +R +R KR WV V E G PQ + +L S+ D+ +
Sbjct: 28 QQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEG 87
Query: 140 KIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDP 198
+ Y+++G GA + VF +++ TG + + LDREE Y L AV E +E
Sbjct: 88 TVKYTLSGDGAGT----VFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPE 143
Query: 199 MNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH 258
I V D ND++PKF + +V E G V+QV ATD DD Y + V YSI
Sbjct: 144 SEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSIL 203
Query: 259 SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVV 316
+P F+I TG I +DRE +Y + IQA DM G G T + +
Sbjct: 204 QGQP------YFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNI 257
Query: 317 EILDANDNAPMFDPQKYEAHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGD 375
+ D NDN P F + VPE++ +G + R+ D D + Y I+ GD G+
Sbjct: 258 TLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNA--EIEYNIVPGDGGN 315
Query: 376 HFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTN---------EAPFVLKLPTSTAT 426
F I T ++ +G++ +K LDFE K +T VE +N PF TAT
Sbjct: 316 LFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPF-----KDTAT 370
Query: 427 IVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRI--LRDPAG 484
+ + V DV+E PVF P +EV E P G + TA+D D + + Y I D
Sbjct: 371 VKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDGDS 430
Query: 485 WLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDH 544
+ +D + G + LDRE Y ++A +P T +L+ ++DVN+
Sbjct: 431 YFTIDGNEGTIATNELLDRESTAQ-----YNFSIIASKVSNPLLTSKVNILINVLDVNEF 485
Query: 545 GP-VPEPRQITICNQSPVRQVLNIT---DKDLSPHTSPFQAQLTDDSDIYWTAEVNE-EG 599
P + P + +C + Q++ I D+DLSP F +L+ ++ I V +
Sbjct: 486 PPEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRN 545
Query: 600 DTVVLSLKKF----LKQDTYDVHLSLSDHGNKEQLTV----IRATVCDCHGHVETCPGPW 651
+T + ++ +Q+ Y + + + D Q + IR CD G + +C
Sbjct: 546 NTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVE- 604
Query: 652 KGGFILPV---LGAVLALLFLLLVLLLLV-----RKKRKIKEPLLLPEDDTRDNVFYYGE 703
LPV GA++A+L +++LL +V +++K K+ L+ ++D RDNV +Y +
Sbjct: 605 --AIFLPVGLSTGALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSKEDIRDNVIHYDD 662
Query: 704 EGGGEED-QDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENL 762
EGGGEED Q +DI L R + E +R D+ P + P RP + +I +FI + L
Sbjct: 663 EGGGEEDTQAFDIGAL-RNPKVIEENKIRRDIKPDSLCLPRQRPPMEDNTDIRDFIHQRL 721
Query: 763 KAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADM 822
+ + DPTAPPYD+L + YEGSGS A SLSS+ S ++ DQDYDYL +WG RFK LADM
Sbjct: 722 QENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLTDWGPRFKVLADM 781
Query: 823 YGGGE 827
+G E
Sbjct: 782 FGEEE 786
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 340 bits (872), Expect = 3e-93
Identities = 256/761 (33%), Positives = 384/761 (50%), Gaps = 56/761 (7%)
Query: 103 RRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVE 161
+R KR WV V E G P + +L S+ DR D I Y ++G GA VF ++
Sbjct: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
Query: 162 KETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDPMNISIIVTDQNDHKPKFTQDTF 220
TG + + LDREE A+Y L A+ G +E I + D ND++PKF +
Sbjct: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
Query: 221 RGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTIS 280
+V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP------YFSVDSKTGVIR 224
Query: 281 VISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
+DRE Y + IQA DM G G T + + D NDN P F + Y+ V
Sbjct: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284
Query: 339 ENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLD 397
E+A + V R+ DLD + + Y I+ GD D F I+T P GI+T +K L
Sbjct: 285 ESAPISSTVGRVFAKDLDEGINAEMK--YTIVDGDGADAFDISTDPNFQVGIITVKKPLS 342
Query: 398 FEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGI 453
FE+K +TL VE N E F+ P T T+ + VEDV+E PVF P VEV E +
Sbjct: 343 FESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDV 402
Query: 454 PTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQFVRN 511
G + + +A+DPD N I Y I R DP + +D +G + LDRE+ +
Sbjct: 403 AIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSW--- 459
Query: 512 NIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVL---NI 567
+ + VLAM+ +P G+ + + ++DVND+ P P + +C + Q++ +
Sbjct: 460 --HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSA 517
Query: 568 TDKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDTVVLSLKKFLKQDTYDV-HLSL--S 622
D+D + F L ++ + +T N++ +L+ + +Q V HL + +
Sbjct: 518 VDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIA 577
Query: 623 DHG----NKEQLTVIRATVCDCHGHVETCPGPWKGGFILPV------LGAVLALLFLLLV 672
D G + I+ CD GHV +C ++LPV L A+LA +F+LLV
Sbjct: 578 DSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPE---AYMLPVSLSRGALIAILACIFVLLV 634
Query: 673 LLLLVRKKRKI-KEPLLLP-EDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVV 729
L+LL+ R+ K+P ++ E++ +N+ Y +EGGGEED + +DI + EA+
Sbjct: 635 LVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAA 694
Query: 730 --LRNDVAPTIIPTPMYRPRP-ANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSG 786
R D+ P I Y P+ A + ++++ L A+ D APP+D+L + +EG G
Sbjct: 695 PKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDG 754
Query: 787 SDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGE 827
S A SLSSL S+ SD +Q +D+L +WG RF+KLA++YG E
Sbjct: 755 SVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 334 bits (856), Expect = 2e-91
Identities = 220/652 (33%), Positives = 331/652 (50%), Gaps = 40/652 (6%)
Query: 88 KERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITG 147
+ ++P K L+R KR W P S+ EN GPFPQ + Q++S+ ++ IFYSI+G
Sbjct: 115 ENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISG 174
Query: 148 PGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTD 207
PG D P +F +EK+TG + + +DRE+ ++ L+G+A + +G + E P+ + I + D
Sbjct: 175 PGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIED 234
Query: 208 QNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT--DEDDAIYTYNGVVAYSIHSQEPKDP 265
ND+ P F +V E GTSV +VTAT DE D ++T + Y I Q P P
Sbjct: 235 DNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTR---LKYKILQQIPDHP 291
Query: 266 HDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDAND 323
F+IH TG I+ + LDREK Y L ++ DM G G T + + D ND
Sbjct: 292 KH--FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDEND 349
Query: 324 NAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHP 383
N P F Y V EN + E+ R+ V D D PN+P +A Y I+ G++ +F I+T P
Sbjct: 350 NPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDP 409
Query: 384 ESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPF----VLKLPT-STATIVVHVEDVNEAP 438
+N+G+L K L++E Q L V V NEA F + PT T T+ V + D +E P
Sbjct: 410 NTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGP 469
Query: 439 VFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KENQKISYRILRDPAGWLAMDPDSGQVTA 497
PP KV++ Q+G P G+ + Y A DP+ + + Y+ L D W ++ +G +
Sbjct: 470 ECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRT 529
Query: 498 VGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICN 557
+ LDRE +FV+NN Y + V+A+D + + TGTL++ L D NDH P + +++TIC
Sbjct: 530 LKVLDRE-SKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQID-KEVTICQ 585
Query: 558 QSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDV 617
+ VL D D + PFQ L + + W E ++G T +L ++ L + Y V
Sbjct: 586 NNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIE-EKDGKTAILRQRQNLDYNYYSV 644
Query: 618 HLSLSDHGNKEQLTVIRATVCDCHGHVE--------------TCPGPWKGGFILPVLGAV 663
+ + D ++ VCDC E G W + VLG+V
Sbjct: 645 PIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRW--AILAMVLGSV 702
Query: 664 LALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDI 715
LL +L V KR +K+ PED + N+ EG GEE + +I
Sbjct: 703 --LLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEANI 750
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 334 bits (856), Expect = 2e-91
Identities = 220/652 (33%), Positives = 331/652 (50%), Gaps = 40/652 (6%)
Query: 88 KERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITG 147
+ ++P K L+R KR W P S+ EN GPFPQ + Q++S+ ++ IFYSI+G
Sbjct: 115 ENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISG 174
Query: 148 PGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTD 207
PG D P +F +EK+TG + + +DRE+ ++ L+G+A + +G + E P+ + I + D
Sbjct: 175 PGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIED 234
Query: 208 QNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT--DEDDAIYTYNGVVAYSIHSQEPKDP 265
ND+ P F +V E GTSV +VTAT DE D ++T + Y I Q P P
Sbjct: 235 DNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTR---LKYKILQQIPDHP 291
Query: 266 HDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDAND 323
F+IH TG I+ + LDREK Y L ++ DM G G T + + D ND
Sbjct: 292 KH--FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDEND 349
Query: 324 NAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHP 383
N P F Y V EN + E+ R+ V D D PN+P +A Y I+ G++ +F I+T P
Sbjct: 350 NPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDP 409
Query: 384 ESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPF----VLKLPT-STATIVVHVEDVNEAP 438
+N+G+L K L++E Q L V V NEA F + PT T T+ V + D +E P
Sbjct: 410 NTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGP 469
Query: 439 VFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KENQKISYRILRDPAGWLAMDPDSGQVTA 497
PP KV++ Q+G P G+ + Y A DP+ + + Y+ L D W ++ +G +
Sbjct: 470 ECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRT 529
Query: 498 VGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICN 557
+ LDRE +FV+NN Y + V+A+D + + TGTL++ L D NDH P + +++TIC
Sbjct: 530 LKVLDRE-SKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQID-KEVTICQ 585
Query: 558 QSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDV 617
+ VL D D + PFQ L + + W E ++G T +L ++ L + Y V
Sbjct: 586 NNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIE-EKDGKTAILRQRQNLDYNYYSV 644
Query: 618 HLSLSDHGNKEQLTVIRATVCDCHGHVE--------------TCPGPWKGGFILPVLGAV 663
+ + D ++ VCDC E G W + VLG+V
Sbjct: 645 PIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRW--AILAMVLGSV 702
Query: 664 LALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDI 715
LL +L V KR +K+ PED + N+ EG GEE + +I
Sbjct: 703 --LLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEANI 750
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 308 bits (788), Expect = 2e-83
Identities = 242/813 (29%), Positives = 377/813 (46%), Gaps = 90/813 (11%)
Query: 82 QERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKI 141
QE L ++ KI+ LRR KR WV+ + + E GPFP+ + +L +N + +
Sbjct: 32 QETDDLTKQTKEKIYQP---LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSL 88
Query: 142 FYSITGPGADSPPE-GVFAVEK-ETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDP 198
Y I+GPG D PE G+F++E E G + +++P+DRE + ++ V + G V+
Sbjct: 89 MYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTS 148
Query: 199 MNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH 258
+ +I ++D NDH P+F + F +V E G + Q+ A D D+ T N V Y +
Sbjct: 149 LIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEE-NTPNSQVLYFLI 207
Query: 259 SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEI 318
SQ P + F + R +G I +S LD E P++TL I+A D ++T V++
Sbjct: 208 SQTPL-LKESGFRVDRLSGEIR-LSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDV 265
Query: 319 LDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFT 378
+ N++ P F + Y+ +PE V RL V D D+P + AWRA + I+ G++ HF
Sbjct: 266 QEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFD 325
Query: 379 ITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVL---------KLPTSTATIVV 429
I+T PE+N+GIL K LD+E + +L + V NE V + ++AT+ V
Sbjct: 326 ISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSV 385
Query: 430 HVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILRDPAGWLAMD 489
V D N+ P F P S +V +EG G + + A DPD + I Y ++ DPA W+++D
Sbjct: 386 QVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ---IRYELVHDPANWVSVD 442
Query: 490 PDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPV-- 547
+SG V V +DRE V N+ Y +++ A+D+G PP T TGTL+L L D+ND+ P
Sbjct: 443 KNSGVVITVEPIDRESPH-VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLR 501
Query: 548 PEPRQITICNQSPVRQVLNI--TDKDLSPHTSPFQAQLTD---DSDIYWTAEVNEEGDTV 602
P R + +C +S V + L+I D DL P + PF +L + +++ W N G +V
Sbjct: 502 PRSRYMEVC-ESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRN-WGQSV 559
Query: 603 VLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKG------GFI 656
L + L + Y V L + D Q + +C C + TC G +
Sbjct: 560 ELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGL-TCVELADAEVGLHVGAL 618
Query: 657 LPVLGAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDIT 716
PV A +AL LL LL + + D+ + Y E G Q +
Sbjct: 619 FPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDV 678
Query: 717 QLHRGL------------------EARPEVVLRNDVAPTIIPT----PMYRPR------- 747
+ R E P ++ A + + + PR
Sbjct: 679 EGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHS 738
Query: 748 -PANPD-------------EIGNFIIENLKAANT---DPTAPPYDTLLVFDYEGSGSDAA 790
PA PD + + + L AN DP P+ V+ EG A
Sbjct: 739 TPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAP 794
Query: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMY 823
SLSSL S +Q+ D L+ GS+ ++Y
Sbjct: 795 SLSSLAS--LEQELQPDLLDSLGSKATPFEEIY 825
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 307 bits (787), Expect = 2e-83
Identities = 240/753 (31%), Positives = 367/753 (48%), Gaps = 59/753 (7%)
Query: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIF-YSITGPGADSPPEGVFAVEK 162
R KR WV VPE + QL+S+ D F Y + G GA S F +++
Sbjct: 40 RVKRGWVWNQFFVPEE-MNTTSHHIGQLRSDLDNGNNSFQYKLLGAGAGS----TFIIDE 94
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
TG + + LDREE + Y L + G +VE I V+D ND++PKF + +
Sbjct: 95 RTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYE 154
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
V E GT V+QVTA+D DD N + YS+ +P F++ +TG I
Sbjct: 155 AIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQP------YFSVEPTTGVIR- 207
Query: 282 ISSGLDREKVPEYTLTIQATDMDGDG---STTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
ISS +DRE EY + IQA DM G S TT+V ++++ D NDN P+F Y V
Sbjct: 208 ISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSV-LIKLSDVNDNKPIFKESLYRLTVS 266
Query: 339 ENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLD 397
E+A G + + D D + + + DD F I T+ E+ +GI+ +K +D
Sbjct: 267 ESAPTGTSIGTIMAYDNDIGENAEMDYS---IEEDDSQTFDIITNHETQEGIVILKKKVD 323
Query: 398 FEAKNQHTLYVEVTN----EAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGI 453
FE +N + + +V N E ST I + VEDV+E P+F+ P V EV E
Sbjct: 324 FEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEET 383
Query: 454 PTGEPVCVYTAEDPDKENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNI 513
P G V V +A DPD I Y I R + D+G +T +LDRE +
Sbjct: 384 PQGSFVGVVSATDPDNRKSPIRYSITRSKVFNIN---DNGTITTSNSLDREISAW----- 435
Query: 514 YEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVLNIT---- 568
Y + + A + + + L + ++++NDH P + + +C + QV+
Sbjct: 436 YNLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVD 495
Query: 569 -DKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLK---KFLKQDTYDVHLSLSDH 624
D+ + H F + D ++ +T N++ V+L+ + ++ + + + ++D+
Sbjct: 496 RDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADN 555
Query: 625 G--NKEQLTVIRATVCDC--HGHVETCPGP---WKGGFILPVLGAVLALLFLLLVLLLLV 677
G + + VCDC G +TC GF V+ A+L + ++ + L
Sbjct: 556 GIPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLT 615
Query: 678 RKKRKIKEPLLLPE--DDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVVLRNDV 734
++ ++ +L PE +D R+N+F Y +EGGGEED + +DI +L R +
Sbjct: 616 LGLKQRRKQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTS 675
Query: 735 APTIIPTPMYRPR-PANPDE--IGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAAS 791
A +YR PD FI+E L+ ANTDP APP+D+L + +EG+GS A S
Sbjct: 676 AEI---RSLYRQSLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGS 732
Query: 792 LSSLTSSASDQDQDYDYLNEWGSRFKKLADMYG 824
LSSL S+ SDQD+ YDYLNE G RFK+LA M+G
Sbjct: 733 LSSLESAVSDQDESYDYLNELGPRFKRLACMFG 765
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 293 bits (750), Expect = 4e-79
Identities = 244/767 (31%), Positives = 363/767 (47%), Gaps = 69/767 (8%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAV 160
L R +R WV V E GP P + +L S+ DR + + Y +TG GA + VF +
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSE-NGASVEDPMNISIIVTDQNDHKPKFTQDT 219
++ TG + + K LDREE A+Y L AV + +E P I V D ND+ P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 220 FRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTI 279
+ +V E GTSV+QVTA D DD Y + + Y++ P F++ TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 280 SVISSGLDREKVPEYTLTIQATDMDG-----DGSTTTAVAVVEILDANDNAPMFDPQKYE 334
+DRE E+ + IQA DM G GSTT V + D NDN P F Y+
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVT---LSDVNDNPPKFPQSLYQ 265
Query: 335 AHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTR 393
V E A G V RL D D ++ Y I+ G+ + F+I+T + G+LT R
Sbjct: 266 FSVVETAGPGTLVGRLRAQDPDLGDNALM--AYSILDGEGSEAFSISTDLQGRDGLLTVR 323
Query: 394 KGLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEV 449
K LDFE++ ++ VE TN + ++ + P A++ V V+D E P F + + V
Sbjct: 324 KPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTV 383
Query: 450 QEGIPTGEPVCVYTAEDPDKENQKISYRIL--RDPAGWLAMDPDSGQVTAVGTLDREDEQ 507
E G V +A D D I Y IL DP ++ P+ G + LDRE
Sbjct: 384 PENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA 443
Query: 508 FVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSP---VRQ 563
+ + + VLA + S + + +D ND+ P + EP +C+ + + Q
Sbjct: 444 W-----HNLTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQ 498
Query: 564 VLNITDKDL---SPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVL--SLKKFLKQDTYDVH 618
V+ D+D S H S FQ L D++ +T + N +G +L S + Y V
Sbjct: 499 VIRALDRDEVGNSSHVS-FQGPLGPDAN--FTVQDNRDGSASLLLPSRPAPPRHAPYLVP 555
Query: 619 LSLSDHGNK--EQLTVIRATVCDCH--GHVETCPGPWKGGFILPV---LGAVLALL---- 667
+ L D G + +VC C G V +C W + GA+LA++
Sbjct: 556 IELWDWGQPALSSTATVTVSVCRCQPDGSVASC---WPEAHLSAAGLSTGALLAIITCVG 612
Query: 668 -FLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEAR 725
L LV+L + +++K + ++L E+D R+N+ Y +EGGGEED + +DIT L A
Sbjct: 613 ALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAA 672
Query: 726 PEVV---LRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDY 782
P R DV P + +PRP P ++ + L+ A+ DP PPYD++ V+ Y
Sbjct: 673 PPAPGPPARRDVLPRARVSR--QPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGY 730
Query: 783 EGSGSDAASLSSL--TSSASDQDQDYDYLNEWGSRFKKLADMYGGGE 827
EG GS SLSSL S A + L++WG F+ LA++YG E
Sbjct: 731 EGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 284 bits (726), Expect = 3e-76
Identities = 240/763 (31%), Positives = 365/763 (47%), Gaps = 71/763 (9%)
Query: 103 RRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEK 162
RR KRDW+ + + E P + ++KS+ R Y + G VF V+
Sbjct: 43 RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNAK-YLLKGEYVGK----VFRVDA 97
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
ETG + + LDRE I++Y L V ++ G ++E P + +I V D ND+ P FT F
Sbjct: 98 ETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFN 157
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
SV E GTSV+ VTA D DD + V Y I + F I S G I
Sbjct: 158 ASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKE------YFAIDNS-GRIIT 210
Query: 282 ISSGLDREKVPEYTLTIQATDMDG-DGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPEN 340
I+ LDREK Y + ++A D G G + TA +V + D NDN P F KY VPE+
Sbjct: 211 ITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPED 270
Query: 341 A-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFE 399
VG V L V D D P + + Y I+ GD D FTI T+P N+GI+ K LD+E
Sbjct: 271 TRVGTSVGSLFVEDPDEPQNRMTK--YSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYE 328
Query: 400 AKNQHTLYVEVTN---EAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTG 456
Q++ VE T+ + ++ + A +++++ DV+E P+F P +++E
Sbjct: 329 YIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKEN--QK 386
Query: 457 EPVC-VYTAEDPDKENQKISYRILRDPAGWLAMDPDSGQ---VTAVGTLDREDEQFVRNN 512
+P+ A DPD I Y I R D GQ VT G + E E +
Sbjct: 387 KPLIGTVLAMDPDAARHSIGYSIRRTS--------DKGQFFRVTKKGDIYNEKE--LDRE 436
Query: 513 IYEVMVLAMDNGSPPTTGTGT-------LLLTLIDVNDHGP-VPEPRQITICNQSPVRQV 564
+Y L ++ +TGT T + + ++D ND+ P +P Q +C + Q+
Sbjct: 437 VYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQL 496
Query: 565 ---LNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVH--- 618
++ DKD++P F+ L +++ T + ++ + + +F ++ T VH
Sbjct: 497 VLQISAIDKDITPRNVKFKFILNTENNFTLT-DNHDNTANITVKYGQFDREHT-KVHFLP 554
Query: 619 LSLSDHG--NKEQLTVIRATVCDCH--GHVETCP--GPWKGGFILPVLGAVLALLFLLLV 672
+ +SD+G ++ + + VC C+ G C G I V+ +L +L + ++
Sbjct: 555 VVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQAVVAILLCILTITVI 614
Query: 673 LLLLVRKKRKIKEPLLLPED--DTRDNVFYYGEEGGGEEDQ-DYDITQLH---RGLEARP 726
LL+ ++R K+ + + + + Y EEGGGE D YD++ L+ RG P
Sbjct: 615 TLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPP 674
Query: 727 EVVLRNDVAPTIIPTPMYRPRPA-----NPDEIGNFIIENLKAANTDPTAPPYDTLLVFD 781
L D P++ PR A P E+ I A+ D PPYDTL ++
Sbjct: 675 RPAL--DARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYG 732
Query: 782 YEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYG 824
YEGS S A SLSSL + +SD D DYD+LN+WG RFK LA++YG
Sbjct: 733 YEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYG 775
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 283 bits (724), Expect = 5e-76
Identities = 245/790 (31%), Positives = 365/790 (46%), Gaps = 90/790 (11%)
Query: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVEK 162
R KR WV V E G P + ++ S+ D D I Y+I+G GA + +F +++
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGT----IFLIDE 114
Query: 163 ETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISII-VTDQNDHKPKFTQDTFR 221
TG + + LDRE+ Y L A + +P + II V D ND +P+F +
Sbjct: 115 LTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI 174
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
GSV E GTSVMQV A+D DD Y + + YS+ E FT+ TG I
Sbjct: 175 GSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHH------FTVDPKTGVIRT 228
Query: 282 ISSGLDREKVPEYTLTIQATDMDGD-----GSTTTAVAVVEILDANDNAPMFDPQKYEAH 336
LDRE Y + IQATDM G GSTT + V D NDN P F + Y+
Sbjct: 229 AVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVT---DVNDNPPRFPQKMYQFS 285
Query: 337 VPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKG 395
+ E+A +G V R+ D D + GD F +TT ++ + I+ +K
Sbjct: 286 IQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKR 345
Query: 396 LDFEAKNQHTLYVEVTNEA--PFVLKLPT--STATIVVHVEDVNEAPVFVPPSKVVEVQE 451
LDFE++ HT+ +E N+ P L T A + V V DV+E P F PPS ++EVQE
Sbjct: 346 LDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQE 405
Query: 452 GIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQFV 509
G V V TA DPD N+ + Y I R D +D D+G + LDRE +
Sbjct: 406 DAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGW- 464
Query: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQS---PVRQVL 565
+ + VLAM+ + +L + ++DVND+ P + P + +C + + Q +
Sbjct: 465 ----HNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTI 520
Query: 566 NITDKDLSPHTSPFQAQLTDDSDI---YWTAEVNEEGDTVVLSLKKF--LKQDTYDVHLS 620
++ D+D F +L ++ + ++ + V F +QD + + +
Sbjct: 521 SVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPIL 580
Query: 621 LSDHG----NKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVL---GAVLALLFLLLVL 673
+ D G + IR CD G +++C F++ GA++ALL +L+L
Sbjct: 581 VVDSGPPTLSSTGTLTIRICGCDSSGTIQSCN---TTAFVMAASLSPGALIALLVCVLIL 637
Query: 674 ----LLLVRKKRKIKEPLLLPED-DTRDNVFYYGEEGGGEEDQD-YDITQLHR------- 720
LL++ +R K L ED D RDNV Y +EGGGE+D + YD++ L
Sbjct: 638 VVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGEL 697
Query: 721 -------------------GLEARPEVVLRNDVAPTIIPTPMYRPRPANPD--EIGNFII 759
G + P+ L ++ P P P PD +FI
Sbjct: 698 KGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERH----SLPQGPPSP-EPDFSVFRDFIS 752
Query: 760 ENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKL 819
+ A+ D + PPYD + +EG+ S AASLSSL S +S +QD+ YL+ WG RF+ L
Sbjct: 753 RKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPL 812
Query: 820 ADMYGGGEDD 829
A +Y G D
Sbjct: 813 AALYAGHRGD 822
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 279 bits (714), Expect = 7e-75
Identities = 247/805 (30%), Positives = 366/805 (45%), Gaps = 107/805 (13%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAV 160
L R +R WV V E GP P + +L S+ DR + + Y +TG GA + VF +
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSE-NGASVEDPMNISIIVTDQNDHKPKFTQDT 219
++ TG + + K LDREE A+Y L AV + +E P I V D ND+ P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 220 FRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTI 279
+ +V E GTSV+QVTA D DD Y + + Y++ P F++ TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 280 SVISSGLDREKVPEYTLTIQATDMDG-----DGSTTTAVAVVEILDANDNAPMFDPQKYE 334
+DRE E+ + IQA DM G GSTT V + D NDN P F Y+
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVT---LSDVNDNPPKFPQSLYQ 265
Query: 335 AHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTR 393
V E A G V RL D D ++ Y I+ G+ + F+I+T + G+LT R
Sbjct: 266 FSVVETAGPGTLVGRLRAQDPDLGDNALM--AYSILDGEGSEAFSISTDLQGRDGLLTVR 323
Query: 394 KGLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEV 449
K LDFE++ ++ VE TN + ++ + P A++ V V+D E P F + + V
Sbjct: 324 KPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTV 383
Query: 450 QEGIPTGEPVCVYTAEDPDKENQKISYRIL--RDPAGWLAMDPDSGQVTAVGTLDREDEQ 507
E G V +A D D I Y IL DP ++ P+ G + LDRE
Sbjct: 384 PENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA 443
Query: 508 FVRNNIYEVMVLAMDNG--------------------------SPPTTGTG--------- 532
+ + + VLA + G SP + G
Sbjct: 444 W-----HNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQA 498
Query: 533 ---TLLLTLIDVNDHGP-VPEPRQITICNQS---PVRQVLNITDKD---LSPHTSPFQAQ 582
+ + +D ND+ P + EP +C+ + + QV+ D+D S H S FQ
Sbjct: 499 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVS-FQGP 557
Query: 583 LTDDSDIYWTAEVNEEGDTVVL--SLKKFLKQDTYDVHLSLSDHGNK--EQLTVIRATVC 638
L D++ +T + N +G +L S + Y V + L D G + +VC
Sbjct: 558 LGPDAN--FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVC 615
Query: 639 DCH--GHVETCPGPWKGGFILPV---LGAVLALL-----FLLLVLLLLVRKKRKIKEPLL 688
C G V +C W + GA+LA++ L LV+L + +++K + ++
Sbjct: 616 RCQPDGSVASC---WPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMV 672
Query: 689 LPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEV---VLRNDVAPTIIPTPMY 744
L E+D R+N+ Y +EGGGEED + +DIT L A P R DV P
Sbjct: 673 LEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPR--ARVSR 730
Query: 745 RPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSL--TSSASDQ 802
+PRP P ++ + L+ A+ DP PPYD++ V+ YEG GS SLSSL S A
Sbjct: 731 QPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGA 790
Query: 803 DQDYDYLNEWGSRFKKLADMYGGGE 827
+ L++WG F+ LA++YG E
Sbjct: 791 PGPAEPLDDWGPLFRTLAELYGAKE 815
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 266 bits (679), Expect = 8e-71
Identities = 173/557 (31%), Positives = 284/557 (50%), Gaps = 29/557 (5%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
+RR KR+W+ + E + +++S+ + + KI Y I+G G D PP GVF +
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
TG + + +DRE + ++ A++ G +E P+ + + V D ND+ P F+Q +
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
S+ E T V+++ ATD D+ + N +AY I SQEP MF ++R TG +
Sbjct: 164 ASIEENSDANTLVVKLCATDADEENHL-NSKIAYKIVSQEPSGAP--MFILNRYTGEVCT 220
Query: 282 ISSGLDREKVPEYTLTIQATDMDG--DGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPE 339
+SS LDRE+ Y L ++ +D DG DG ++ +++LD NDN P + Y A + E
Sbjct: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280
Query: 340 NAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFE 399
N + E+ RL DLD + W A YLI+ G+DG+ F I T P++N+GIL K LD+E
Sbjct: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340
Query: 400 AKNQHTLYVEVTNEAPFVLKLPTS----TATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
L + V N+A F + + + + V DV E P F P + V+EGI
Sbjct: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400
Query: 456 GE----PVCVYTAEDPDKEN--QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFV 509
+ YTA D D N + Y I D WL +D +G++ D++ +++
Sbjct: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKK-SKYI 459
Query: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITD 569
N IY +LA+D+GS T TGT+ + + D+ND+ P P + TIC SP ++++ +
Sbjct: 460 INGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSP-SVLISVNE 517
Query: 570 KDLSPHTSPFQAQLTDD----SDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHG 625
+ SPF + D+ +D++ N + +L+ K+ L Y++ + + D
Sbjct: 518 HS---YGSPFTFCVVDEPPGIADMWDVRSTN--ATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 626 NK--EQLTVIRATVCDC 640
N+ E +++ CDC
Sbjct: 573 NRACELAQMVQLYACDC 589
Score = 31.2 bits (69), Expect = 4.1
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 765 ANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADM 822
A+ D P D LL++D+EG GS S+ + D D+ + +F+ LA++
Sbjct: 810 ADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 865
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 266 bits (679), Expect = 8e-71
Identities = 173/557 (31%), Positives = 284/557 (50%), Gaps = 29/557 (5%)
Query: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
+RR KR+W+ + E + +++S+ + + KI Y I+G G D PP GVF +
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
TG + + +DRE + ++ A++ G +E P+ + + V D ND+ P F+Q +
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
S+ E T V+++ ATD D+ + N +AY I SQEP MF ++R TG +
Sbjct: 164 ASIEENSDANTLVVKLCATDADEENHL-NSKIAYKIVSQEPSGAP--MFILNRYTGEVCT 220
Query: 282 ISSGLDREKVPEYTLTIQATDMDG--DGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPE 339
+SS LDRE+ Y L ++ +D DG DG ++ +++LD NDN P + Y A + E
Sbjct: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280
Query: 340 NAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFE 399
N + E+ RL DLD + W A YLI+ G+DG+ F I T P++N+GIL K LD+E
Sbjct: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340
Query: 400 AKNQHTLYVEVTNEAPFVLKLPTS----TATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
L + V N+A F + + + + V DV E P F P + V+EGI
Sbjct: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400
Query: 456 GE----PVCVYTAEDPDKEN--QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFV 509
+ YTA D D N + Y I D WL +D +G++ D++ +++
Sbjct: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKK-SKYI 459
Query: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITD 569
N IY +LA+D+GS T TGT+ + + D+ND+ P P + TIC SP ++++ +
Sbjct: 460 INGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSP-SVLISVNE 517
Query: 570 KDLSPHTSPFQAQLTDD----SDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHG 625
+ SPF + D+ +D++ N + +L+ K+ L Y++ + + D
Sbjct: 518 HS---YGSPFTFCVVDEPPGIADMWDVRSTN--ATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 626 NK--EQLTVIRATVCDC 640
N+ E +++ CDC
Sbjct: 573 NRACELAQMVQLYACDC 589
Score = 31.2 bits (69), Expect = 4.1
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 765 ANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADM 822
A+ D P D LL++D+EG GS S+ + D D+ + +F+ LA++
Sbjct: 791 ADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 846
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,609,639
Number of Sequences: 37866
Number of extensions: 1802323
Number of successful extensions: 7237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3343
Number of HSP's gapped (non-prelim): 919
length of query: 829
length of database: 18,247,518
effective HSP length: 111
effective length of query: 718
effective length of database: 14,044,392
effective search space: 10083873456
effective search space used: 10083873456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.