Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 109689707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109689707 transmembrane phosphatase with tensin homology
isoform alpha [Homo sapiens]
(551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109689707 transmembrane phosphatase with tensin homology isof... 1100 0.0
gi|40549433 transmembrane phosphatase with tensin homology isofo... 1054 0.0
gi|40549435 transmembrane phosphatase with tensin homology isofo... 993 0.0
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 918 0.0
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 741 0.0
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 620 e-178
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 206 6e-53
gi|66529407 tensin [Homo sapiens] 124 2e-28
gi|65288071 tensin 3 [Homo sapiens] 122 1e-27
gi|157384971 cyclin G associated kinase [Homo sapiens] 119 7e-27
gi|38787970 tensin like C1 domain containing phosphatase isoform... 108 2e-23
gi|38787957 tensin like C1 domain containing phosphatase isoform... 108 2e-23
gi|38787941 tensin like C1 domain containing phosphatase isoform... 108 2e-23
gi|239756009 PREDICTED: similar to transmembrane phosphoinositid... 103 3e-22
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 97 3e-20
gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens] 64 3e-10
gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens] 64 3e-10
gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo... 46 1e-04
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] 45 2e-04
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi... 43 9e-04
gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H... 42 0.002
gi|205277447 dual specificity phosphatase 11 [Homo sapiens] 42 0.002
gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo sa... 41 0.002
gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo sa... 41 0.002
gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H... 41 0.003
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I... 41 0.003
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I... 41 0.003
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 39 0.012
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 39 0.012
gi|126362955 sodium channel, voltage-gated, type III, alpha isof... 39 0.016
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 1100 bits (2845), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL 60
MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL
Sbjct: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL 60
Query: 61 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 120
ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
Sbjct: 61 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 120
Query: 121 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 180
YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
Sbjct: 121 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 180
Query: 181 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 240
IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
Sbjct: 181 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 240
Query: 241 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 300
YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
Sbjct: 241 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 300
Query: 301 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 360
RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
Sbjct: 301 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 360
Query: 361 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 420
TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
Sbjct: 361 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 420
Query: 421 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 480
IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF
Sbjct: 421 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 480
Query: 481 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
Sbjct: 481 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
Query: 541 MTSSDVVAGSD 551
MTSSDVVAGSD
Sbjct: 541 MTSSDVVAGSD 551
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 1054 bits (2725), Expect = 0.0
Identities = 533/551 (96%), Positives = 533/551 (96%), Gaps = 18/551 (3%)
Query: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL 60
MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAK ESVL
Sbjct: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAK------------------ESVL 42
Query: 61 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 120
ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
Sbjct: 43 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 102
Query: 121 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 180
YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
Sbjct: 103 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 162
Query: 181 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 240
IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
Sbjct: 163 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 222
Query: 241 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 300
YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
Sbjct: 223 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 282
Query: 301 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 360
RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
Sbjct: 283 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 342
Query: 361 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 420
TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
Sbjct: 343 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 402
Query: 421 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 480
IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF
Sbjct: 403 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 462
Query: 481 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
Sbjct: 463 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 522
Query: 541 MTSSDVVAGSD 551
MTSSDVVAGSD
Sbjct: 523 MTSSDVVAGSD 533
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 993 bits (2568), Expect = 0.0
Identities = 507/551 (92%), Positives = 508/551 (92%), Gaps = 38/551 (6%)
Query: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL 60
MNESPDPTDLAGVIIELGPNDSPQTSE FKGA +P ES
Sbjct: 1 MNESPDPTDLAGVIIELGPNDSPQTSE------------------FKGATEEAPAKES-- 40
Query: 61 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 120
SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
Sbjct: 41 ------------------SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL 82
Query: 121 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 180
YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
Sbjct: 83 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD 142
Query: 181 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 240
IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
Sbjct: 143 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT 202
Query: 241 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 300
YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
Sbjct: 203 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV 262
Query: 301 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 360
RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
Sbjct: 263 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS 322
Query: 361 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 420
TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
Sbjct: 323 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI 382
Query: 421 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 480
IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF
Sbjct: 383 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF 442
Query: 481 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
Sbjct: 443 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 502
Query: 541 MTSSDVVAGSD 551
MTSSDVVAGSD
Sbjct: 503 MTSSDVVAGSD 513
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 918 bits (2372), Expect = 0.0
Identities = 458/521 (87%), Positives = 485/521 (93%)
Query: 20 NDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYDS 79
N+SPQT+EFKG TEEAPAKESPHTSEFKGAA VSPIS+S+L RLSKFEVEDAENVASYDS
Sbjct: 2 NESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYDS 61
Query: 80 KIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLM 139
KIKKIVHSIVSSFAFG+FGVFLVLLDVTL+LADLIFTDSKLYIPLEYRSISLAI LFFLM
Sbjct: 62 KIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLM 121
Query: 140 DVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRL 199
DVLLRVFVE RQQYFSDLFNILDTAIIVI LLVDV+YIFFDIKLLRNIPRWTHL+RLLRL
Sbjct: 122 DVLLRVFVEGRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIPRWTHLVRLLRL 181
Query: 200 IILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 259
IIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF
Sbjct: 182 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 241
Query: 260 YRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFT 319
YRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRV RIMIDDHNVPTLH+MVVFT
Sbjct: 242 YRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFT 301
Query: 320 KEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHS 379
KEVNEWMAQDLENIVAIHCKGG RTGTMVCA LIASEI TA+ESLYYFGERRT+KTHS
Sbjct: 302 KEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHS 361
Query: 380 EKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEK 439
KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFIK FIIYSI V DLK+Q+ MEK
Sbjct: 362 NKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEK 421
Query: 440 KVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLH 499
KVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDVKVQFF SNLP YYDNC F+FW +
Sbjct: 422 KVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFN 481
Query: 500 TSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEILFGEK
Sbjct: 482 TSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 522
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 741 bits (1912), Expect = 0.0
Identities = 384/521 (73%), Positives = 409/521 (78%), Gaps = 77/521 (14%)
Query: 20 NDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYDS 79
N+SPQT+EFKG TEEAPAKESPHTSEFKGAA VSPIS+ +
Sbjct: 2 NESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRI-------------------- 41
Query: 80 KIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLM 139
FGVFLVLLDVTL+LADLIFTDSKLYIPLEYRSISLAI LFFLM
Sbjct: 42 -----------------FGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLM 84
Query: 140 DVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRL 199
DVLLRVFVE WTHL+RLLRL
Sbjct: 85 DVLLRVFVE----------------------------------------GWTHLVRLLRL 104
Query: 200 IILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 259
IIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF
Sbjct: 105 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 164
Query: 260 YRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFT 319
YRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRV RIMIDDHNVPTLH+MVVFT
Sbjct: 165 YRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFT 224
Query: 320 KEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHS 379
KEVNEWMAQDLENIVAIHCKGG RTGTMVCA LIASEI TA+ESLYYFGERRT+KTHS
Sbjct: 225 KEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHS 284
Query: 380 EKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEK 439
KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFIK FIIYSI V DLK+Q+ MEK
Sbjct: 285 NKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEK 344
Query: 440 KVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLH 499
KVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDVKVQFF SNLP YYDNC F+FW +
Sbjct: 345 KVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFN 404
Query: 500 TSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEILFGEK
Sbjct: 405 TSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 445
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 620 bits (1600), Expect = e-178
Identities = 303/364 (83%), Positives = 327/364 (89%), Gaps = 2/364 (0%)
Query: 179 FDIKLLRNIP--RWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFD 236
F+++ N+ WTHL+RLLRLIIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFD
Sbjct: 48 FEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 107
Query: 237 LDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 296
LDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFH
Sbjct: 108 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 167
Query: 297 NRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIAS 356
NRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIHCKGG RTGTMVCA LIAS
Sbjct: 168 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 227
Query: 357 EICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFI 416
EI TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFI
Sbjct: 228 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 287
Query: 417 KHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDV 476
K FIIYSI V DLK+Q+ MEKKVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDV
Sbjct: 288 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 347
Query: 477 KVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEIL 536
KVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEIL
Sbjct: 348 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 407
Query: 537 FGEK 540
FGEK
Sbjct: 408 FGEK 411
Score = 104 bits (260), Expect = 2e-22
Identities = 51/59 (86%), Positives = 56/59 (94%)
Query: 20 NDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYD 78
N+SPQT+EFKG TEEAPAKESPHTSEFKGAA VSPIS+S+L RLSKFEVEDAENVASY+
Sbjct: 2 NESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 206 bits (523), Expect = 6e-53
Identities = 126/360 (35%), Positives = 194/360 (53%), Gaps = 56/360 (15%)
Query: 218 LIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRN 277
+I+ VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I +VVRFLD KH+N
Sbjct: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
Query: 278 HYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIH 337
HY++YNLC+ER YD F+ RV + +DHN P L + F +++++W+++D ++ AIH
Sbjct: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
Query: 338 CKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRT-DKTHSEKFQGVETPSQKRYVAY 396
CK G RTG M+CA+L+ A+E+L ++GE RT DK +GV PSQ+RYV Y
Sbjct: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK------KGVTIPSQRRYVYY 177
Query: 397 FAQVKHLYNWNLPPRRILFIKHFIIY-SIPRY----VRDLKIQIEMEKKVVFSTISLGKC 451
++ +L +L R + + H +++ +IP + + +++ K+ S +
Sbjct: 178 YS---YLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTR- 233
Query: 452 SVLDNITTDKILIDVF-DGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFI------- 503
DK + F LP+ D+KV+FF+ + F+FW++T FI
Sbjct: 234 ------REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS 287
Query: 504 ----------------------ENNRLY----LPKNELDNLHKQKARRIYPSDFAVEILF 537
+N++ Y L KN+LD +K KA R + +F V++ F
Sbjct: 288 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 124 bits (311), Expect = 2e-28
Identities = 90/313 (28%), Positives = 152/313 (48%), Gaps = 17/313 (5%)
Query: 229 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 288
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
Query: 289 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 348
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
Query: 349 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWN 407
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + N
Sbjct: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
Query: 408 LPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILI 464
P LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCI 234
Query: 465 DVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKAR 524
+ GL L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 235 TIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR- 293
Query: 525 RIYPSDFAVEILF 537
+P VE +F
Sbjct: 294 --FPEYGKVEFVF 304
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 122 bits (305), Expect = 1e-27
Identities = 88/323 (27%), Positives = 154/323 (47%), Gaps = 26/323 (8%)
Query: 233 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDP 292
+G LDLTY+TERIIA+SFP+ + Y + ++EV R L KH ++Y V NL SE+ YD
Sbjct: 3 EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
Query: 293 KHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAF 352
+ +++ + + + P L +M K W+ +L+++V IHC+GG R G ++ ++
Sbjct: 62 TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
Query: 353 LIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411
+ + + ++A ++L F + K + +K + PSQKRYV + + + N P
Sbjct: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
Query: 412 RILFIKHFIIYSIPRYVRD------LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILID 465
LF+ I++ P + LK+ M+ ++G +I I
Sbjct: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGP------ENPSRICIV 229
Query: 466 VFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 525
+ L DV V+ ++ + + F HT ++ L K +LDN K
Sbjct: 230 IEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR-- 287
Query: 526 IYPSDFAVEILFG---EKMTSSD 545
+P VE++F EK+ S+
Sbjct: 288 -FPDYGKVELVFSATPEKIQGSE 309
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 119 bits (298), Expect = 7e-27
Identities = 63/165 (38%), Positives = 89/165 (53%), Gaps = 9/165 (5%)
Query: 236 DLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHF 295
DLD++Y+T RI MSFP+ G +S +N I++V FLD KH HY VYNL S R Y P F
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNL-SPRTYRPSRF 465
Query: 296 HNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIA 355
HNRV P LH + + ++ W+ QD +N+ +HC G + VC+FL
Sbjct: 466 HNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCF 525
Query: 356 SEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQV 400
+ STA+ ++Y F +R G+ PS KRY+ Y +
Sbjct: 526 CRLFSTAEAAVYMFSMKRCP-------PGI-WPSHKRYIEYMCDM 562
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 108 bits (269), Expect = 2e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 235 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 294
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 5 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 63
Query: 295 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 354
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 64 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 123
Query: 355 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 124 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 177
Query: 412 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 468
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 178 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 232
Query: 469 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 528
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 233 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 289
Query: 529 SDFAVEILFGEKMTSSDVVAGS 550
+VE +F +S + + GS
Sbjct: 290 FQASVEFVFS---SSPEKIKGS 308
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 108 bits (269), Expect = 2e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 235 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 294
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
Query: 295 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 354
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
Query: 355 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 248 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 301
Query: 412 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 468
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 302 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 356
Query: 469 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 528
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 357 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 413
Query: 529 SDFAVEILFGEKMTSSDVVAGS 550
+VE +F +S + + GS
Sbjct: 414 FQASVEFVFS---SSPEKIKGS 432
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 108 bits (269), Expect = 2e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 235 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 294
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
Query: 295 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 354
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
Query: 355 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 258 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 311
Query: 412 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 468
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 312 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 366
Query: 469 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 528
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 367 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 423
Query: 529 SDFAVEILFGEKMTSSDVVAGS 550
+VE +F +S + + GS
Sbjct: 424 FQASVEFVFS---SSPEKIKGS 442
>gi|239756009 PREDICTED: similar to transmembrane phosphoinositide
3-phosphatase and tensin homolog 2, partial [Homo
sapiens]
Length = 99
Score = 103 bits (258), Expect = 3e-22
Identities = 47/55 (85%), Positives = 49/55 (89%)
Query: 287 ERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 341
ERAYDPKHFHNRV RIMIDDHNVPTL +MV F+KEV EWMAQD ENIV IHCKGG
Sbjct: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGG 83
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 97.4 bits (241), Expect = 3e-20
Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 13/180 (7%)
Query: 222 RVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRV 281
RV ++ YT+ DLD TYVT RII MSFP +RN + ++ FLD +H +HY V
Sbjct: 51 RVIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTV 108
Query: 282 YNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 341
YNL S ++Y FH+RV P+LH + + + W+ Q+ +N+ +HC G
Sbjct: 109 YNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDG 167
Query: 342 TDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE-TPSQKRYVAYFAQV 400
+ +V A I + ST ++ +R G+ +PS +RY+ Y +
Sbjct: 168 RAASSILVGAMFIFCNLYSTPGPAIRLLYAKR---------PGIGLSPSHRRYLGYMCDL 218
>gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 64.3 bits (155), Expect = 3e-10
Identities = 38/131 (29%), Positives = 71/131 (54%), Gaps = 18/131 (13%)
Query: 84 IVHSIVSSFAFGLFGVFLVLLDVTLILADLIFT------DSKLYIPLEYRSISLAIALFF 137
++ + SS F + + LV+LD L+LA+LI D Y + + +S+ I +FF
Sbjct: 91 MLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFF 150
Query: 138 LMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLL 197
+M+++ ++FV R ++F F ILD ++V+ ++D+V +F + H L
Sbjct: 151 MMEIIFKLFV-FRLEFFHHKFEILDAVVVVVSFILDIVLLFQE-----------HQFEAL 198
Query: 198 RLIILLRIFHL 208
L+ILLR++ +
Sbjct: 199 GLLILLRLWRV 209
>gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 64.3 bits (155), Expect = 3e-10
Identities = 38/131 (29%), Positives = 71/131 (54%), Gaps = 18/131 (13%)
Query: 84 IVHSIVSSFAFGLFGVFLVLLDVTLILADLIFT------DSKLYIPLEYRSISLAIALFF 137
++ + SS F + + LV+LD L+LA+LI D Y + + +S+ I +FF
Sbjct: 91 MLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFF 150
Query: 138 LMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLL 197
+M+++ ++FV R ++F F ILD ++V+ ++D+V +F + H L
Sbjct: 151 MMEIIFKLFV-FRLEFFHHKFEILDAVVVVVSFILDIVLLFQE-----------HQFEAL 198
Query: 198 RLIILLRIFHL 208
L+ILLR++ +
Sbjct: 199 GLLILLRLWRV 209
>gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo
sapiens]
Length = 1980
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 79 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL 138
+KI+ IV V+ AF + + L+ L++ ++ + T SK + Y I+L +FF
Sbjct: 1509 NKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETD-TQSKQMENILYW-INLVFVIFFT 1566
Query: 139 MDVLLRVFVERRQQYFSDLFNILDTAIIVI----LLLVDVVYIFFDIKLLRNIPRWTHLL 194
+ +L++F R YF+ +NI D ++++ + L D++ +F L + R +
Sbjct: 1567 CECVLKMFA-LRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIG 1625
Query: 195 RLLRLI 200
R+LRLI
Sbjct: 1626 RILRLI 1631
>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
Length = 1177
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 4/145 (2%)
Query: 83 KIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVL 142
+I H+IV + F G ++L+++ + I + +Y E + + ++++ L
Sbjct: 602 RICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHS-ELKHTNYCFLTLYILEAL 660
Query: 143 LRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIIL 202
L++ R+ +FS +NI + AI +I +L ++ IK + N +++++ +
Sbjct: 661 LKI-AAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRI 719
Query: 203 LRIFHLFHQKRQLEKLIRRRVSENK 227
LRIF L K L ++I +R+S K
Sbjct: 720 LRIFKLIAPK--LLQIIDKRMSHQK 742
>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapiens]
Length = 1836
Score = 42.7 bits (99), Expect = 9e-04
Identities = 32/126 (25%), Positives = 69/126 (54%), Gaps = 7/126 (5%)
Query: 79 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL 138
+KI+ +V+ +V+ AF + + L+ L++ ++ + S+L + + Y +I++ + F
Sbjct: 1340 NKIQGMVYDLVTKQAFDITIMILICLNMVTMMVETD-NQSQLKVDILY-NINMIFIIIFT 1397
Query: 139 MDVLLRVFVERRQQYFSDLFNILDTAIIVI----LLLVDVVYIFFDIKLLRNIPRWTHLL 194
+ +L++ RQ YF+ +NI D ++++ L L D++ +F L + R +
Sbjct: 1398 GECVLKMLA-LRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIG 1456
Query: 195 RLLRLI 200
R+LRLI
Sbjct: 1457 RVLRLI 1462
Score = 29.6 bits (65), Expect = 7.5
Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
Query: 25 TSEFKGATE--EAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYDSKIK 82
T+++K E E A+E+P +G +E+ + R V+ ++ ++
Sbjct: 967 TADYKPPEEDPEEQAEENP-----EGEQPEECFTEACVQRWPCLYVDISQGRGKKWWTLR 1021
Query: 83 KIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVL 142
+ IV F F VF++LL + + I+ + + I F+M++L
Sbjct: 1022 RACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEML 1081
Query: 143 LRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHL-----LRLL 197
L+ + YF++ + LD L+VDV I L+ N ++ L LR L
Sbjct: 1082 LKWVAYGFKVYFTNAWCWLD------FLIVDVSI----ISLVANWLGYSELGPIKSLRTL 1131
Query: 198 RLIILLRIFHLFHQKR 213
R + LR F R
Sbjct: 1132 RALRPLRALSRFEGMR 1147
>gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform a [Homo sapiens]
Length = 2353
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Query: 62 RLSKFEVEDAENVASYD--SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSK 119
R S F +A+ Y S ++ +HS+ +S LF F++ ++V + +
Sbjct: 1585 RRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKS 1644
Query: 120 LYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFF 179
L L+Y + I F + L F RR +F D +N LD AI+++ L+ +
Sbjct: 1645 LDEALKYCNYVFTIVFVFEAALKLVAFGFRR--FFKDRWNQLDLAIVLLSLMGITLE--- 1699
Query: 180 DIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLI 219
+I++ +P ++R++R++ + R+ L + L+
Sbjct: 1700 EIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALL 1739
>gi|205277447 dual specificity phosphatase 11 [Homo sapiens]
Length = 377
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 286 SERAYDPKHFHNRV--VRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLEN--IVAIHCKGG 341
++R Y P+ V ++I H VP + F VN ++ ++ +N ++ +HC G
Sbjct: 143 TQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHCTHG 202
Query: 342 TDRTGTMVCAFLIASE 357
+RTG ++C +LI E
Sbjct: 203 LNRTGYLICRYLIDVE 218
>gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo
sapiens]
Length = 530
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/130 (25%), Positives = 69/130 (53%), Gaps = 12/130 (9%)
Query: 94 FGLFGVFLVLLDVTLILADLIF---TDSKLY-IPLEYRSISLAIALFFLMDVLLRVFVER 149
F F +FLV L+ +++ ++ T++KL+ + L + I L F++++LL+ ++
Sbjct: 110 FKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK-WLSN 168
Query: 150 RQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLF 209
++ +N+ D + ++ LL +VV +L + + L+LLR+ +LR L
Sbjct: 169 FSVFWKSAWNVFDFVVTMLSLLPEVV-------VLVGVTGQSVWLQLLRICRVLRSLKLL 221
Query: 210 HQKRQLEKLI 219
Q RQ++ +I
Sbjct: 222 AQFRQIQIII 231
>gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo
sapiens]
Length = 528
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/130 (25%), Positives = 69/130 (53%), Gaps = 12/130 (9%)
Query: 94 FGLFGVFLVLLDVTLILADLIF---TDSKLY-IPLEYRSISLAIALFFLMDVLLRVFVER 149
F F +FLV L+ +++ ++ T++KL+ + L + I L F++++LL+ ++
Sbjct: 110 FKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK-WLSN 168
Query: 150 RQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLF 209
++ +N+ D + ++ LL +VV +L + + L+LLR+ +LR L
Sbjct: 169 FSVFWKSAWNVFDFVVTMLSLLPEVV-------VLVGVTGQSVWLQLLRICRVLRSLKLL 221
Query: 210 HQKRQLEKLI 219
Q RQ++ +I
Sbjct: 222 AQFRQIQIII 231
>gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform b [Homo sapiens]
Length = 2347
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/141 (22%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 79 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL 138
S ++ +HS+ +S LF F++ ++V + + L L+Y + I F
Sbjct: 1598 SPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFE 1657
Query: 139 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR 198
+ L F RR +F D +N LD AI+++ L+ + +I++ +P ++R++R
Sbjct: 1658 AALKLVAFGFRR--FFKDRWNQLDLAIVLLSLMGITLE---EIEMSAALPINPTIIRIMR 1712
Query: 199 LIILLRIFHLFHQKRQLEKLI 219
++ + R+ L + L+
Sbjct: 1713 VLRIARVLKLLKMATGMRALL 1733
>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform b [Homo sapiens]
Length = 2188
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/136 (19%), Positives = 69/136 (50%), Gaps = 5/136 (3%)
Query: 84 IVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLL 143
++HS+ +S +F F++ L+V + + + L L+Y + F+++ +L
Sbjct: 1444 LIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKY--CNYMFTTVFVLEAVL 1501
Query: 144 RVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILL 203
++ +++F D +N LD AI+++ ++ + +I++ +P ++R++R++ +
Sbjct: 1502 KLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLE---EIEINAALPINPTIIRIMRVLRIA 1558
Query: 204 RIFHLFHQKRQLEKLI 219
R+ L + L+
Sbjct: 1559 RVLKLLKMATGMRALL 1574
>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform a [Homo sapiens]
Length = 2223
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/136 (19%), Positives = 69/136 (50%), Gaps = 5/136 (3%)
Query: 84 IVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLL 143
++HS+ +S +F F++ L+V + + + L L+Y + F+++ +L
Sbjct: 1479 LIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKY--CNYMFTTVFVLEAVL 1536
Query: 144 RVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILL 203
++ +++F D +N LD AI+++ ++ + +I++ +P ++R++R++ +
Sbjct: 1537 KLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLE---EIEINAALPINPTIIRIMRVLRIA 1593
Query: 204 RIFHLFHQKRQLEKLI 219
R+ L + L+
Sbjct: 1594 RVLKLLKMATGMRALL 1609
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 280 RVYNLCSERAYDP----KHFHNRVVRIMIDDHNVP-TLHQMVVFTKEVNEWMAQDL-ENI 333
R + +C E D +HFH V DH VP T ++ F + V +++ +
Sbjct: 2062 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 2117
Query: 334 VAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRY 393
+HC G RTGT + I ++ S K+S+ +G + H + V+T Q Y
Sbjct: 2118 TVVHCSAGVGRTGTFIALDRILQQLDS--KDSVDIYGAVHDLRLH--RVHMVQTECQYVY 2173
Query: 394 V 394
+
Sbjct: 2174 L 2174
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 280 RVYNLCSERAYDP----KHFHNRVVRIMIDDHNVP-TLHQMVVFTKEVNEWMAQDL-ENI 333
R + +C E D +HFH V DH VP T ++ F + V +++ +
Sbjct: 1844 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 1899
Query: 334 VAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRY 393
+HC G RTGT + I ++ S K+S+ +G + H + V+T Q Y
Sbjct: 1900 TVVHCSAGVGRTGTFIALDRILQQLDS--KDSVDIYGAVHDLRLH--RVHMVQTECQYVY 1955
Query: 394 V 394
+
Sbjct: 1956 L 1956
>gi|126362955 sodium channel, voltage-gated, type III, alpha isoform 3
[Homo sapiens]
Length = 1951
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/126 (23%), Positives = 62/126 (49%), Gaps = 7/126 (5%)
Query: 79 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL 138
+K + +V V+ F + + L+ L++ ++ + D Y+ L I+L + F
Sbjct: 1464 NKFQGMVFDFVTRQVFDISIMILICLNMVTMMVET--DDQGKYMTLVLSRINLVFIVLFT 1521
Query: 139 MDVLLRVFVERRQQYFSDLFNILDTAIIVI----LLLVDVVYIFFDIKLLRNIPRWTHLL 194
+ +L++ V R YF+ +NI D ++++ + L +++ +F L + R +
Sbjct: 1522 GEFVLKL-VSLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIG 1580
Query: 195 RLLRLI 200
R+LRLI
Sbjct: 1581 RILRLI 1586
Score = 36.6 bits (83), Expect = 0.061
Identities = 42/197 (21%), Positives = 77/197 (39%), Gaps = 18/197 (9%)
Query: 25 TSEFKGATEEAPAKESPHTSEFKGAARVSP---ISESVLARLSKFEVEDAENVASYDSKI 81
TS +G+T + +E + + P +E + + +V E +
Sbjct: 1087 TSSSEGSTVDVVLPREGEQAETEPEEDLKPEACFTEGCIKKFPFCQVSTEEGKGKIWWNL 1146
Query: 82 KKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDV 141
+K +SIV F F VF++LL + + I+ + + I F++++
Sbjct: 1147 RKTCYSIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEM 1206
Query: 142 LLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHL-----LRL 196
LL+ Q YF++ + LD I+ + L + L+ N ++ L LR
Sbjct: 1207 LLKWVAYGFQTYFTNAWCWLDFLIVDVSL----------VSLVANALGYSELGAIKSLRT 1256
Query: 197 LRLIILLRIFHLFHQKR 213
LR + LR F R
Sbjct: 1257 LRALRPLRALSRFEGMR 1273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,225,369
Number of Sequences: 37866
Number of extensions: 826425
Number of successful extensions: 2935
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 2718
Number of HSP's gapped (non-prelim): 241
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.