Guide to the Human Genome
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Search of human proteins with 14249119

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249119 Rhox homeobox family, member 2 [Homo sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14249119 Rhox homeobox family, member 2 [Homo sapiens]             594   e-170
gi|153791494 Rhox homeobox family, member 2B [Homo sapiens]           589   e-169
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...   116   2e-26
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]    82   7e-16
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...    82   7e-16
gi|7706659 paired related homeobox 2 [Homo sapiens]                    81   9e-16
gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]              80   2e-15
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                77   1e-14
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  77   1e-14
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  77   1e-14
gi|24497589 aristaless related homeobox [Homo sapiens]                 75   9e-14
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          74   1e-13
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...    74   1e-13
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    74   2e-13
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             73   3e-13
gi|46249382 paired-like homeobox 2a [Homo sapiens]                     73   3e-13
gi|14149760 orthopedia homeobox [Homo sapiens]                         73   3e-13
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                  70   2e-12
gi|152963644 paired-like homeodomain transcription factor 1 [Hom...    70   2e-12
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]      69   4e-12
gi|239757894 PREDICTED: similar to Rhox homeobox family, member ...    69   5e-12
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       68   8e-12
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       68   8e-12
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     68   8e-12
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]                67   2e-11
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     67   2e-11
gi|4826912 paired-like homeodomain 3 [Homo sapiens]                    66   3e-11
gi|21361183 paired-like homeodomain transcription factor 2 isofo...    66   3e-11
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 66   3e-11
gi|7110735 ventral anterior homeobox 2 [Homo sapiens]                  66   3e-11

>gi|14249119 Rhox homeobox family, member 2 [Homo sapiens]
          Length = 288

 Score =  594 bits (1532), Expect = e-170
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL 60
           MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL
Sbjct: 1   MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL 60

Query: 61  KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSR 120
           KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSR
Sbjct: 61  KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSR 120

Query: 121 PQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQI 180
           PQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQI
Sbjct: 121 PQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQI 180

Query: 181 WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS 240
           WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS
Sbjct: 181 WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS 240

Query: 241 SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV 288
           SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV
Sbjct: 241 SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV 288


>gi|153791494 Rhox homeobox family, member 2B [Homo sapiens]
          Length = 288

 Score =  589 bits (1519), Expect = e-169
 Identities = 286/288 (99%), Positives = 287/288 (99%)

Query: 1   MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL 60
           MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL
Sbjct: 1   MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKL 60

Query: 61  KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSR 120
           KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEG+LEGTSGSDGNVEDSDQSEKEPGQQYSR
Sbjct: 61  KSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQYSR 120

Query: 121 PQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQI 180
           PQGAVGGLEPGNAQQPNVHAFTPLQLQELE IFQREQFPSEFLRRRLARSMNVTELAVQI
Sbjct: 121 PQGAVGGLEPGNAQQPNVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQI 180

Query: 181 WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS 240
           WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS
Sbjct: 181 WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS 240

Query: 241 SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV 288
           SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV
Sbjct: 241 SLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV 288


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score =  116 bits (291), Expect = 2e-26
 Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 32/258 (12%)

Query: 20  DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79
           +D +E+ D    V SL     E+EE+ + +PE GT A   + + G+   +++D     ++
Sbjct: 21  EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQD-----RE 75

Query: 80  GGGAGVPGHLWEGDL----EGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVG-----GLEP 130
           GGG   P    E       E        +E   + E+ P      PQ A G     G +P
Sbjct: 76  GGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135

Query: 131 GNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWR 190
              ++    AFT  QLQELE  F   Q+P    R RLA  +N+TE  VQ+WF+NRRAKW+
Sbjct: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195

Query: 191 RHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPM-PPF 249
           R+QR LM RN             TA  A    +F+ G    Y+   +   +LC  + P  
Sbjct: 196 RNQRVLMLRN-----------TATADLAHPLDMFLGGA---YYAAPALDPALCVHLVPQL 241

Query: 250 P-PPSLPLPLMLLPPMPP 266
           P PP LP+P M  PP PP
Sbjct: 242 PRPPVLPVPPM--PPRPP 257



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)

Query: 245 PMPPFPP----PSLPLPLMLLPPMPPAGQAEFGPFPFVIVP 281
           P+PP+PP    P+ P P+  +PP PP  +   GP P   VP
Sbjct: 302 PVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-PMARVP 340


>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
          Length = 217

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 47/124 (37%), Positives = 68/124 (54%), Gaps = 22/124 (17%)

Query: 97  TSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQRE 156
           TSGSD   +D+DQ   E  ++                Q+ N   F   QLQ LER+F+R 
Sbjct: 71  TSGSDTPQQDNDQLNSEEKKK--------------RKQRRNRTTFNSSQLQALERVFERT 116

Query: 157 QFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFM--------AVG 208
            +P  F+R  LAR +N+TE  VQ+WF+NRRAK+RR++RA++A      +        AV 
Sbjct: 117 HYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVE 176

Query: 209 QPVM 212
           QP++
Sbjct: 177 QPIV 180


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 47/124 (37%), Positives = 68/124 (54%), Gaps = 22/124 (17%)

Query: 97  TSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQRE 156
           TSGSD   +D+DQ   E  ++                Q+ N   F   QLQ LER+F+R 
Sbjct: 71  TSGSDTPQQDNDQLNSEEKKK--------------RKQRRNRTTFNSSQLQALERVFERT 116

Query: 157 QFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFM--------AVG 208
            +P  F+R  LAR +N+TE  VQ+WF+NRRAK+RR++RA++A      +        AV 
Sbjct: 117 HYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVE 176

Query: 209 QPVM 212
           QP++
Sbjct: 177 QPIV 180


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 81.3 bits (199), Expect = 9e-16
 Identities = 62/203 (30%), Positives = 91/203 (44%), Gaps = 31/203 (15%)

Query: 51  EQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQS 110
           E+  AAG      GA+  E ++G   E  GG               +SGS+   +D +  
Sbjct: 47  EEVAAAGRLAARPGARA-EAREGAAREPSGG---------------SSGSEAAPQDGECP 90

Query: 111 EKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARS 170
               G    R +           Q+ N   F   QLQ LER+F+R  +P  F+R  LAR 
Sbjct: 91  SPGRGSAAKRKK----------KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARR 140

Query: 171 MNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRD 230
           +N++E  VQ+WF+NRRAK+RR++RA++A      +         A E   AP   +   D
Sbjct: 141 VNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLK--SYSQEAAIEQPVAPRPTALSPD 198

Query: 231 DYFWDHSHSSSLCFPMPPFPPPS 253
              W    +SS    +PP+ P S
Sbjct: 199 YLSWT---ASSPYSTVPPYSPGS 218


>gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]
          Length = 184

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 55/163 (33%), Positives = 79/163 (48%), Gaps = 22/163 (13%)

Query: 48  PEPEQGTAAGEK----LKSAGAQGGEEKDGGGEEKDG---GGAGVPGHLWEGDLEGTSGS 100
           P P+ G A+  +      + G  G    +GG   ++G    G  +P            G 
Sbjct: 23  PTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIP-----------EGG 71

Query: 101 DGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHA-FTPLQLQELERIFQREQFP 159
            GN E   Q +  P +     Q A+ G +P N Q       FT LQ++ELE +F+  Q+P
Sbjct: 72  GGNQEPRQQPQPPPEEP---AQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYP 128

Query: 160 SEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNML 202
               RR LA ++ VTE  V++WF+N+RA+ RRHQR LM  N L
Sbjct: 129 DVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANEL 171


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 43/210 (20%)

Query: 68  GEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGG 127
           G+    G ++++GGG            E T+    N EDSD+++                
Sbjct: 170 GQPTQDGCQQQEGGG------------ENTNSISSNGEDSDEAQMR-------------- 203

Query: 128 LEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRA 187
           L+     Q N  +FT  Q++ LE+ F+R  +P  F R RLA  +++ E  +Q+WF NRRA
Sbjct: 204 LQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRA 263

Query: 188 KWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPL---------FISGM---RDDYFWD 235
           KWRR ++    R          P+  + + ++  P+         F SG    R D    
Sbjct: 264 KWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALT 323

Query: 236 HSHSSSLCFPMPPFPPPSLPLPLMLLPPMP 265
           +++S+     +PP P  ++   L + PP+P
Sbjct: 324 NTYSA-----LPPMPSFTMANNLPMQPPVP 348


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 43/210 (20%)

Query: 68  GEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGG 127
           G+    G ++++GGG            E T+    N EDSD+++                
Sbjct: 184 GQPTQDGCQQQEGGG------------ENTNSISSNGEDSDEAQMR-------------- 217

Query: 128 LEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRA 187
           L+     Q N  +FT  Q++ LE+ F+R  +P  F R RLA  +++ E  +Q+WF NRRA
Sbjct: 218 LQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRA 277

Query: 188 KWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPL---------FISGM---RDDYFWD 235
           KWRR ++    R          P+  + + ++  P+         F SG    R D    
Sbjct: 278 KWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALT 337

Query: 236 HSHSSSLCFPMPPFPPPSLPLPLMLLPPMP 265
           +++S+     +PP P  ++   L + PP+P
Sbjct: 338 NTYSA-----LPPMPSFTMANNLPMQPPVP 362


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 43/210 (20%)

Query: 68  GEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGG 127
           G+    G ++++GGG            E T+    N EDSD+++                
Sbjct: 170 GQPTQDGCQQQEGGG------------ENTNSISSNGEDSDEAQMR-------------- 203

Query: 128 LEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRA 187
           L+     Q N  +FT  Q++ LE+ F+R  +P  F R RLA  +++ E  +Q+WF NRRA
Sbjct: 204 LQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRA 263

Query: 188 KWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPL---------FISGM---RDDYFWD 235
           KWRR ++    R          P+  + + ++  P+         F SG    R D    
Sbjct: 264 KWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALT 323

Query: 236 HSHSSSLCFPMPPFPPPSLPLPLMLLPPMP 265
           +++S+     +PP P  ++   L + PP+P
Sbjct: 324 NTYSA-----LPPMPSFTMANNLPMQPPVP 348


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 77/278 (27%), Positives = 114/278 (41%), Gaps = 34/278 (12%)

Query: 20  DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79
           DDE+EL +         E ++++EE+   +  +      +     A G            
Sbjct: 225 DDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVAT 284

Query: 80  GGGAGVPGH---LWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQP 136
            GG   P     L   D EG  G D +V  S  S+ E G    +             Q+ 
Sbjct: 285 EGGELSPKEELLLHPEDAEGKDGED-SVCLSAGSDSEEGLLKRK-------------QRR 330

Query: 137 NVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRAL 196
               FT  QL+ELER FQ+  +P  F R  LA  +++TE  VQ+WF+NRRAKWR+ ++A 
Sbjct: 331 YRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAG 390

Query: 197 MARNM--LPFMAVGQPVMVTAAEAITAPLFISGM------RDDYFWDHSHSSSLCFPMPP 248
              +   LPF     P  ++A   ++  L  S         D  +   + +++  FP  P
Sbjct: 391 AQTHPPGLPF-----PGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLP 445

Query: 249 FPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFP 286
            PP S  LP    P   P G + F        P+F  P
Sbjct: 446 PPPGSASLP----PSGAPLGLSTFLGAAVFRHPAFISP 479


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 64/205 (31%), Positives = 96/205 (46%), Gaps = 36/205 (17%)

Query: 25  LQDMNAMVL-SLTEEVKEEEE--------DAQP-----EPEQGTAAGEKLKSAGA---QG 67
           ++++ A V  S  ++VKE++E        ++ P     EP   T AG   +S+ A    G
Sbjct: 1   MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG 60

Query: 68  GEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSD----QSEKEPG-------- 115
           G    GGG    GGG GV G    G   G  G    V + D    +  +EPG        
Sbjct: 61  GGGGGGGGGGGGGGGGGVGGG---GAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVS 117

Query: 116 -QQYSRPQGAVGGLEPGNA---QQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSM 171
            +   R + A G  + G     Q+ +   FT  QL ELER+F    +P  F+R  L++ +
Sbjct: 118 PELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRL 177

Query: 172 NVTELAVQIWFENRRAKWRRHQRAL 196
            ++E  VQ+WF+NRRAK R+ +  L
Sbjct: 178 GLSEARVQVWFQNRRAKCRKQENQL 202


>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 34/167 (20%)

Query: 126 GGLEPGNAQQPNVH-----AFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQI 180
           GGL PG       H      FT  QL +LER F+   +P  + R  LA  +++ E+ VQ+
Sbjct: 14  GGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQV 73

Query: 181 WFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSS 240
           WF+NRRAKWRR +R                 + + + A+ AP         +    +   
Sbjct: 74  WFQNRRAKWRRQER-----------------LESGSGAVAAPRLPEAPALPF----ARPP 112

Query: 241 SLCFPMPPF---PPPSLP-LPLMLLPPMPPAGQAEFGPFPFVIVPSF 283
           ++  P+ P+    PP++P LP +L P   P  QA FGP  F   P+F
Sbjct: 113 AMSLPLEPWLGPGPPAVPGLPRLLGP--GPGLQASFGPHAF--APTF 155


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 53/177 (29%), Positives = 77/177 (43%), Gaps = 22/177 (12%)

Query: 112 KEPGQQYSRPQGAVGGL----------EPGNAQQPNVHAFTPLQLQELERIFQREQFPSE 161
           KEPG+    P   VG            +P    + N   FT  QL ELER F++  +P  
Sbjct: 104 KEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDV 163

Query: 162 FLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNML---PFMAVGQ-PVMVTAAE 217
           + R  LA  +N+ E+ VQ+WF+NRRAKWRR ++  ++   L   P ++  + P   T + 
Sbjct: 164 YSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATLSP 223

Query: 218 AITAPLFISGMRDDYFWDHS--------HSSSLCFPMPPFPPPSLPLPLMLLPPMPP 266
               P    G         S          ++    +P F PP+  LP    PP PP
Sbjct: 224 LGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPP 280


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 48/145 (33%), Positives = 70/145 (48%), Gaps = 8/145 (5%)

Query: 111 EKEPGQQYSRPQGAVGGLEPGNAQQPNVHA-FTPLQLQELERIFQREQFPSEFLRRRLAR 169
           +K+PG Q   P  +  G + G  +Q      FTP QL ELER F +  +P  F+R  LA 
Sbjct: 81  DKQPGPQ-GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELAL 139

Query: 170 SMNVTELAVQIWFENRRAKWRRHQRAL----MARNMLPFMAVGQ-PVMVTAAEAITAPLF 224
            + +TE  VQ+WF+NRRAKW++ ++          +LP   + Q P    AA A      
Sbjct: 140 RIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSL 199

Query: 225 ISGMRDDYFWDHSHSSSLC-FPMPP 248
            S   +D  W  +    +   P+PP
Sbjct: 200 CSFHANDTRWAAAAMPGVSQLPLPP 224


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 54/157 (34%), Positives = 72/157 (45%), Gaps = 24/157 (15%)

Query: 127 GLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRR 186
           GL     Q+     FT  QL+ELER+F    +P  + R  LA  +++TE  VQ+WF+NRR
Sbjct: 83  GLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRR 142

Query: 187 AKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFP- 245
           AK+R+ +RA  A+      A G      AA A       S   DD         S C P 
Sbjct: 143 AKFRKQERAASAKG-----AAG------AAGAKKGEARCSSEDDD------SKESTCSPT 185

Query: 246 ------MPPFPPPSLPLPLMLLPPMPPAGQAEFGPFP 276
                 +PP P P L  P +   P+P A  +  GP P
Sbjct: 186 PDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGP 222


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 48/145 (33%), Positives = 70/145 (48%), Gaps = 8/145 (5%)

Query: 111 EKEPGQQYSRPQGAVGGLEPGNAQQPNVHA-FTPLQLQELERIFQREQFPSEFLRRRLAR 169
           +K+PG Q   P  +  G + G  +Q      FTP QL ELER F +  +P  F+R  LA 
Sbjct: 81  DKQPGPQ-GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELAL 139

Query: 170 SMNVTELAVQIWFENRRAKWRRHQRAL----MARNMLPFMAVGQ-PVMVTAAEAITAPLF 224
            + +TE  VQ+WF+NRRAKW++ ++          +LP   + Q P    AA A      
Sbjct: 140 RIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSL 199

Query: 225 ISGMRDDYFWDHSHSSSLC-FPMPP 248
            S   +D  W  +    +   P+PP
Sbjct: 200 CSFHANDTRWAAAAMPGVSQLPLPP 224


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 16/148 (10%)

Query: 137 NVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR-A 195
           N   FT  QL+ELE++FQ+  +P  + R +LA   ++TE  VQ+WF+NRRAKWR+ +R  
Sbjct: 217 NRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFG 276

Query: 196 LMARNMLPFMAVGQPVMVTAAE---AITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPP 252
            M +    F    +  ++T AE    I  P ++             ++    P+P    P
Sbjct: 277 QMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLG------------NNGAASPVPACVVP 324

Query: 253 SLPLPLMLLPPMPPAGQAEFGPFPFVIV 280
             P+P  + P   P G        F+ V
Sbjct: 325 CDPVPACMSPHAHPPGSGASSVTDFLSV 352


>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
           sapiens]
          Length = 314

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 11/110 (10%)

Query: 95  EGTSGSDGNVEDSDQSEKEPGQQYSRPQGA-VGGLEPGNAQQP---------NVHAFTPL 144
           E    S     D++  EKE G +   P+ +  GG   G A  P           H FT  
Sbjct: 41  EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTH-FTSQ 99

Query: 145 QLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR 194
           QLQELE  FQR ++P   +R  +A   N+TE  V++WF+NRRAKWR+ +R
Sbjct: 100 QLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149


>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
          Length = 326

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 28/54 (51%), Positives = 41/54 (75%)

Query: 141 FTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR 194
           FT LQL+ELE++FQ+  +P  ++R +LA    +TE  VQ+WF+NRRAKWR+ +R
Sbjct: 139 FTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRER 192


>gi|239757894 PREDICTED: similar to Rhox homeobox family, member 1
           [Homo sapiens]
          Length = 177

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 36/77 (46%), Positives = 49/77 (63%), Gaps = 1/77 (1%)

Query: 127 GLEPGNAQQPNVHA-FTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185
           G +P N Q       FT LQ++ELE +F+  Q+P    RR LA ++ VTE  V++WF+N+
Sbjct: 3   GPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNK 62

Query: 186 RAKWRRHQRALMARNML 202
           RA+ RRHQR LM  N L
Sbjct: 63  RARCRRHQRELMLANEL 79


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 22/152 (14%)

Query: 67  GGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGN-VEDSDQSEKEPGQQYSRPQGAV 125
           G +E++   ++K+  G     H     ++G  G  GN +++    E EP     R Q   
Sbjct: 165 GKKEEEDEADKKEDDGEKKAKH----SIDGILGDKGNRLDEGSDVESEPDLPLKRKQ--- 217

Query: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185
                    + +   FT  QL+ELE+ F+R  +P  + R  LA+   +TE  VQ+WF NR
Sbjct: 218 ---------RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNR 268

Query: 186 RAKWRRHQRA--LMARN-MLP--FMAVGQPVM 212
           RA+WR+   A  L A N +LP  F   G P +
Sbjct: 269 RARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 22/152 (14%)

Query: 67  GGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGN-VEDSDQSEKEPGQQYSRPQGAV 125
           G +E++   ++K+  G     H     ++G  G  GN +++    E EP     R Q   
Sbjct: 163 GKKEEEDEADKKEDDGEKKAKH----SIDGILGDKGNRLDEGSDVESEPDLPLKRKQ--- 215

Query: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185
                    + +   FT  QL+ELE+ F+R  +P  + R  LA+   +TE  VQ+WF NR
Sbjct: 216 ---------RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNR 266

Query: 186 RAKWRRHQRA--LMARN-MLP--FMAVGQPVM 212
           RA+WR+   A  L A N +LP  F   G P +
Sbjct: 267 RARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 298


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 22/152 (14%)

Query: 67  GGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGN-VEDSDQSEKEPGQQYSRPQGAV 125
           G +E++   ++K+  G     H     ++G  G  GN +++    E EP     R Q   
Sbjct: 165 GKKEEEDEADKKEDDGEKKAKH----SIDGILGDKGNRLDEGSDVESEPDLPLKRKQ--- 217

Query: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185
                    + +   FT  QL+ELE+ F+R  +P  + R  LA+   +TE  VQ+WF NR
Sbjct: 218 ---------RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNR 268

Query: 186 RAKWRRHQRA--LMARN-MLP--FMAVGQPVM 212
           RA+WR+   A  L A N +LP  F   G P +
Sbjct: 269 RARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300


>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
          Length = 226

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 38/176 (21%)

Query: 120 RPQGAVGG---LEPGNAQQPNVHA-------FTPLQLQELERIFQREQFPSEFLRRRLAR 169
           R  GA GG     P   Q+   H+       F+P+QL++LE  F R Q+P  + R  LAR
Sbjct: 45  RLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLAR 104

Query: 170 SMNVTELAVQIWFENRRAKWRRHQRALM----------------ARNMLPFMAVGQPVMV 213
              ++E  +Q+WF+NRRAK R+ +R+L+                     P+     P  V
Sbjct: 105 DTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSPAAFSSFLPESTACPYSYAAPPPPV 164

Query: 214 TA----------AEAITAPLF-ISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPL 258
           T           ++  T   F +S   +D++     + +   P PP PPP LPL L
Sbjct: 165 TCFPHPYSHALPSQPSTGGAFALSHQSEDWYPTLHPAPAGHLPCPP-PPPMLPLSL 219


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 32/73 (43%), Positives = 45/73 (61%)

Query: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185
           GGL     Q+     FT  QL+ELER+F    +P  + R  LA  +++TE  VQ+WF+NR
Sbjct: 90  GGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNR 149

Query: 186 RAKWRRHQRALMA 198
           RAK+R+ +RA  A
Sbjct: 150 RAKFRKQERAAAA 162


>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
          Length = 302

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 8/92 (8%)

Query: 115 GQQYSRPQGAVGGLEPGNAQQPNVHA--------FTPLQLQELERIFQREQFPSEFLRRR 166
           GQ++S  + A   L  G+ +  ++          FT  QLQELE  FQR ++P    R  
Sbjct: 35  GQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE 94

Query: 167 LARSMNVTELAVQIWFENRRAKWRRHQRALMA 198
           +A   N+TE  V++WF+NRRAKWR+ +R+  A
Sbjct: 95  IAVWTNLTEARVRVWFKNRRAKWRKRERSQQA 126


>gi|21361183 paired-like homeodomain transcription factor 2 isoform
           c [Homo sapiens]
          Length = 324

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 5/93 (5%)

Query: 107 SDQSEKEPGQQYSRPQGA---VGGLEPGNAQQPNVHA--FTPLQLQELERIFQREQFPSE 161
           SD S  E  ++    QG    VG  +P   ++       FT  QLQELE  FQR ++P  
Sbjct: 60  SDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDM 119

Query: 162 FLRRRLARSMNVTELAVQIWFENRRAKWRRHQR 194
             R  +A   N+TE  V++WF+NRRAKWR+ +R
Sbjct: 120 STREEIAVWTNLTEARVRVWFKNRRAKWRKRER 152


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 27/58 (46%), Positives = 41/58 (70%)

Query: 137 NVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR 194
           N   F+  QL+ELE++FQ+  +P  + R +LA   ++TE  VQ+WF+NRRAKWR+ +R
Sbjct: 156 NRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRER 213


>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
          Length = 290

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 74/281 (26%), Positives = 114/281 (40%), Gaps = 55/281 (19%)

Query: 45  DAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSD--G 102
           D   E ++G A   +    G + G+    G    DGGG          ++ GTS S   G
Sbjct: 3   DGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPT------EVAGTSASSPAG 56

Query: 103 NVEDSDQSEKEPGQQYSR---------PQGAVG------GLEPGNAQQPNVHAFTPLQLQ 147
           + E    S+ +PG   +           +G +       GL+    ++    +FT  QL 
Sbjct: 57  SRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRT-SFTAEQLY 115

Query: 148 ELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQ-------------R 194
            LE  FQR Q+     R  LAR +N++E  V++WF+NRR K ++ Q              
Sbjct: 116 RLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASE 175

Query: 195 ALMARNMLPFMAVGQPVMVTAAEAITA-----PLFISGMRDDYFWDHSHSSSLCFPM--- 246
           A    N+L  +  G+ + V  A ++ A     P   +  R     D  +SS    P+   
Sbjct: 176 AFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSA 235

Query: 247 ---PPFPPPSLP------LPLMLLPPMPPAGQAEFGPFPFV 278
              PP PPP LP       PL+ LP     G + F P+ ++
Sbjct: 236 SASPPLPPP-LPAVCFSSAPLLDLPAGYELGSSAFEPYSWL 275


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,586,717
Number of Sequences: 37866
Number of extensions: 880321
Number of successful extensions: 10307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 461
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 7004
Number of HSP's gapped (non-prelim): 3002
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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