Guide to the Human Genome
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Search of human proteins with 14165288

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165288 IQ motif containing G [Homo sapiens]
         (443 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197313718 IQ motif containing G [Homo sapiens]                     870   0.0  
gi|14165288 IQ motif containing G [Homo sapiens]                      870   0.0  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    59   1e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    59   1e-08
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    58   2e-08
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    57   3e-08
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              57   4e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     56   7e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    55   1e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    54   3e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    54   3e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     54   3e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   54   3e-07
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           54   3e-07
gi|19923981 IQ motif containing D [Homo sapiens]                       54   4e-07
gi|4502443 dystonin isoform 1e precursor [Homo sapiens]                52   8e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    52   1e-06
gi|187761324 shootin1 isoform a [Homo sapiens]                         52   1e-06
gi|50511340 shootin1 isoform b [Homo sapiens]                          52   1e-06
gi|38044112 restin isoform b [Homo sapiens]                            52   1e-06
gi|4506751 restin isoform a [Homo sapiens]                             52   1e-06
gi|148746195 trichohyalin [Homo sapiens]                               51   2e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    51   2e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    51   2e-06
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       50   3e-06
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    50   3e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    50   3e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    50   3e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       50   3e-06
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    50   3e-06

>gi|197313718 IQ motif containing G [Homo sapiens]
          Length = 443

 Score =  870 bits (2249), Expect = 0.0
 Identities = 443/443 (100%), Positives = 443/443 (100%)

Query: 1   MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD 60
           MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD
Sbjct: 1   MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD 60

Query: 61  VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS 120
           VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS
Sbjct: 61  VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS 120

Query: 121 PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA 180
           PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA
Sbjct: 121 PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA 180

Query: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240
           DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE
Sbjct: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240

Query: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM 300
           VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM
Sbjct: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM 300

Query: 301 KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ 360
           KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ
Sbjct: 301 KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ 360

Query: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK 420
           DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK
Sbjct: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK 420

Query: 421 DKVDSKDSKGKGKGKDKRRGKKK 443
           DKVDSKDSKGKGKGKDKRRGKKK
Sbjct: 421 DKVDSKDSKGKGKGKDKRRGKKK 443


>gi|14165288 IQ motif containing G [Homo sapiens]
          Length = 443

 Score =  870 bits (2249), Expect = 0.0
 Identities = 443/443 (100%), Positives = 443/443 (100%)

Query: 1   MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD 60
           MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD
Sbjct: 1   MEEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIPEIPETLEPLSLPD 60

Query: 61  VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS 120
           VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS
Sbjct: 61  VLRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPS 120

Query: 121 PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA 180
           PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA
Sbjct: 121 PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA 180

Query: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240
           DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE
Sbjct: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240

Query: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM 300
           VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM
Sbjct: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRM 300

Query: 301 KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ 360
           KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ
Sbjct: 301 KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ 360

Query: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK 420
           DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK
Sbjct: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPK 420

Query: 421 DKVDSKDSKGKGKGKDKRRGKKK 443
           DKVDSKDSKGKGKGKDKRRGKKK
Sbjct: 421 DKVDSKDSKGKGKGKDKRRGKKK 443


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 77/324 (23%), Positives = 147/324 (45%), Gaps = 32/324 (9%)

Query: 138 RFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQ 197
           R+  E  K +D +  +  R TI T E LK+     Q          ++LQ   +  S +Q
Sbjct: 193 RYIEELTKERDALSLELYRNTI-TDEELKEKNAKLQ----------EKLQLVESEKSEIQ 241

Query: 198 ALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEV----------QSQNEY 247
              KE + K+    ++  +++ + +   L K+L +V  + Q +V          Q Q E 
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301

Query: 248 IANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLR----MKTE 303
           +   ++++QE + K   +   ++   E +I + ++K  R EE++ E+ EK+R    M  E
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEE-KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360

Query: 304 EEARTHTEIEMFLRKEQQ--KLEERLEFWMEKYDKDTEMKQNELNALKATKASDL-AHLQ 360
           +E +     EM   KE++  +LEE++    EK  +  E +Q E    +  K  +  A + 
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419

Query: 361 DLAKMIREYEQVIIEDRIEKERSKKKV--KQDLLELKSVIKLQAWWRGTMIRREIGGFKM 418
              + IRE E+ I E   +  R ++K+  ++ + E +   + +  WR     RE      
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479

Query: 419 PKDKVDSKDSKGKGKGKDKRRGKK 442
            K+K+  ++   K + K  R+ +K
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEK 503



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 55/284 (19%), Positives = 130/284 (45%), Gaps = 33/284 (11%)

Query: 166 KKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIIS 225
           +++Q +       +     +LQ     N L   L++++E KM       +EEK       
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW-----RQEEK------- 308

Query: 226 LQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQ---- 281
                    +EW+ ++Q Q E I   +++++E + K   +   M    E    Q +    
Sbjct: 309 --------IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360

Query: 282 --KKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTE 339
             +K  R EE++ E+ EK+R   E E + H + ++  ++E+++ EE++    ++ +++ +
Sbjct: 361 KEEKMRRLEEMMWEKEEKIR---ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417

Query: 340 MKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIK 399
           M + E    K  +  +    Q+  KM R+ E++  +++I +E  +++ ++   + + + +
Sbjct: 418 MWRQEE---KIREQEEKIREQE-KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473

Query: 400 LQAWWRGTMIRREIGGFKMPKDKVDSKDSKGKGKGKDKRRGKKK 443
            +  WR      E    +  ++KV  ++ K   + +  R  ++K
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 44/199 (22%), Positives = 95/199 (47%), Gaps = 33/199 (16%)

Query: 203 RENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKS 262
           +E KMH      +EEK R+Q   + +Q   ++++ + +++ Q E I   ++ +QE + K 
Sbjct: 500 QEEKMH-----DQEEKIREQEEKMWRQEEKIREQEE-KIREQEEKIREQEEMMQEQEEKM 553

Query: 263 NLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTE---EEARTHTEIEMFLRKE 319
             +   M         Q Q+K  R EE + E+ EK+R + E   E+     E E  +R++
Sbjct: 554 GEQEEKM---------QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604

Query: 320 QQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIE 379
           ++ ++E+ E   E+ +K  E ++                +Q+  + +R  E+ + E  + 
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEK---------------MQEQEEKMRRQEEKMWEQEVR 649

Query: 380 KERSKKKVKQDLLELKSVI 398
             + ++K+++    L++ I
Sbjct: 650 LRQQEEKMQEHQEHLEAAI 668



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 44/204 (21%), Positives = 102/204 (50%), Gaps = 11/204 (5%)

Query: 197 QALSKERENKMHFYD--IIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
           Q   +E+E KM   +  I  +EEK R+Q   + +Q   + ++ +   + + +    +  Q
Sbjct: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467

Query: 255 LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEI-- 312
            ++++ +  +  +  K + + +I + ++K  R EE + ++ EK+R + E+  R   +I  
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527

Query: 313 -EMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAH-----LQDLAKMI 366
            E  +R++++K+ E+ E   E+ +K  E ++      K  +  +        +++  + I
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587

Query: 367 REYEQVIIEDRIEKERSKKKVKQD 390
           RE E+ I E   EK R ++++ Q+
Sbjct: 588 REQEEKIWEQE-EKIREQEEMMQE 610



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 38/151 (25%), Positives = 81/151 (53%), Gaps = 15/151 (9%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKA 260
           +E+E KM       +EEK R+Q   +++Q   ++++ +  +Q Q E +   ++++QE + 
Sbjct: 512 REQEEKMW-----RQEEKIREQEEKIREQEEKIREQEEM-MQEQEEKMGEQEEKMQEQEK 565

Query: 261 KSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLR-----MKTEEEARTHTEIEMF 315
               E +  +   E +I + ++K    EE + E+ EK+R     M+ +EE     E +M 
Sbjct: 566 MRRQEEKIREQ--EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623

Query: 316 LRKEQ-QKLEERLEFWMEK-YDKDTEMKQNE 344
            ++E+ Q+ EE++    EK ++++  ++Q E
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 58/258 (22%), Positives = 125/258 (48%), Gaps = 30/258 (11%)

Query: 163  ETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAR--EEKGR 220
            E   ++   +Q   +++ D    +++    N +LQ  +++++ + H  D+  +  EE+G 
Sbjct: 908  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQ--NEKKKMQAHIQDLEEQLDEEEGA 965

Query: 221  KQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQE-MKAKSNLENRYMKTNTEL---- 275
            +Q + L+K     K      ++   E I  L+DQ  + +K K  +E+R  + +++L    
Sbjct: 966  RQKLQLEKVTAEAK------IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019

Query: 276  QIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK---EQQKLEER---LEF 329
            + A+   K    +E+++ ++E+ R+K EE  +T  E+E   RK   E   L+++   L+ 
Sbjct: 1020 EKAKNLAKIRNKQEVMISDLEE-RLKKEE--KTRQELEKAKRKLDGETTDLQDQIAELQA 1076

Query: 330  WMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI--IEDRIEKERSKK-- 385
             +++       K+ EL    A    +  H  +  K++RE +  I  +++  E E++ +  
Sbjct: 1077 QIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNK 1136

Query: 386  --KVKQDLLELKSVIKLQ 401
              K K+DL E    +K +
Sbjct: 1137 AEKQKRDLSEELEALKTE 1154



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 56/226 (24%), Positives = 110/226 (48%), Gaps = 33/226 (14%)

Query: 195 LLQALSKERENKMH----FYDIIAREEKGRKQIISLQKQLINVK------------KEWQ 238
           +L  L +ER+ K+     F+  + R    RK     Q+QL  +K            + WQ
Sbjct: 774 VLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQ 833

Query: 239 F-EVQSQNEYIANLKDQLQEMKAKSN--LENRYMKTNTELQIAQTQKKCNRTEELLVEE- 294
           +  V ++ + +  +  Q +E++AK    L+ +  +T  E ++ + ++K    ++LL E+ 
Sbjct: 834 WWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERK---HQQLLEEKN 890

Query: 295 --IEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATK 352
              E+L+ +TE  A    E+   L  ++Q+LEE L     + +++ E  Q     L+  K
Sbjct: 891 ILAEQLQAETELFAEAE-EMRARLAAKKQELEEILHDLESRVEEEEERNQ----ILQNEK 945

Query: 353 ASDLAHLQDLAKMIREYE---QVIIEDRIEKERSKKKVKQDLLELK 395
               AH+QDL + + E E   Q +  +++  E   KK+++++L L+
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLE 991



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 46/230 (20%), Positives = 104/230 (45%), Gaps = 26/230 (11%)

Query: 202  ERENKM---HFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQ-- 256
            ER+NK       D+++ ++   K +  L+K     K+  + +V+     +  L+D+LQ  
Sbjct: 1503 ERQNKQLRADMEDLMSSKDDVGKNVHELEKS----KRALEQQVEEMRTQLEELEDELQAT 1558

Query: 257  -EMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEAR-------T 308
             + K +  +  + MK   E  +    ++    + LL++++ +L  + E+E +       +
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618

Query: 309  HTEIEMFLRKEQQKLE----ERLEFWMEKYDKDTEMK--QNELNALKATKASDLAHLQDL 362
              ++E+ L+  + ++E     R E   +      +MK  Q EL   +A++    A  ++ 
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678

Query: 363  AKMIREYEQVII---EDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMI 409
             K ++  E  I+   E+    ER+++  +Q+  EL   I   A  +  ++
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1728



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/262 (20%), Positives = 114/262 (43%), Gaps = 37/262 (14%)

Query: 156  RQTIMTTETLKKIQIDRQFFSDVIADT----IKELQDSATYNSLLQALSKERENKMHFYD 211
            R  +   E   K+Q +    S ++ +     IK  +D+A+  S LQ             +
Sbjct: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQ----------E 1322

Query: 212  IIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKT 271
            ++  E + +  + S  +QL   K   Q + + + E   NL+ Q+  +  +S L +   K 
Sbjct: 1323 LLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV--LALQSQLADTKKKV 1380

Query: 272  NTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEE------ 325
            + +L   ++ ++  +    L+++ E L  + EE+A  + ++E    + QQ+L++      
Sbjct: 1381 DDDLGTIESLEEAKKK---LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437

Query: 326  ---RLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK--------MIREYEQVII 374
               ++   +EK  K  +    E  ++ A  A +    +  A+        + R  E+  +
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEA-L 1496

Query: 375  EDRIEKERSKKKVKQDLLELKS 396
            E + E ER  K+++ D+ +L S
Sbjct: 1497 EAKEEFERQNKQLRADMEDLMS 1518


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 94/481 (19%), Positives = 209/481 (43%), Gaps = 62/481 (12%)

Query: 4   DSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIPKETDIEIIP--EIPETLEPLSLP-- 59
           D+    +L  ++ H+  T+S  G   +    E  P    ++ +P  +I   L  +S    
Sbjct: 473 DAARHCDLQVRIDHTSRTLSF-GSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLA 531

Query: 60  ---DVLRISAVLEDTTDQ--LSILNYIMPVQYEGRQSIC----VKSREMNLEGTNL--DK 108
              +V++ + +L++  +Q  L++  Y+   + E ++ +     ++ R+  LE  N+  +K
Sbjct: 532 KALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREK 591

Query: 109 LPMASTITKIPSPLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKI 168
             +     ++      EE     E + R +  +     Q  + KK  R+ +   E +KK 
Sbjct: 592 EELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQ--IKKKTVRERL---EQIKKT 646

Query: 169 QIDRQFFSDVIADTIKELQDSATYNSLLQALSKER----------ENKMHFYDIIAREEK 218
           ++  + F D+  + ++EL         ++ L KE+          E K+ +++   R E+
Sbjct: 647 ELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEE 706

Query: 219 GRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIA 278
                 + ++Q I     W+   Q + E I  +  QL+  KA  + +NR  +   +  + 
Sbjct: 707 IPLIKSAYEEQRIKDMDLWE---QQEEERITTM--QLEREKALEH-KNRMSRMLEDRDLF 760

Query: 279 QTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDT 338
             + K  R + +  E++++   +  EE   H  +E   RK Q+K E R+ ++ EK +++ 
Sbjct: 761 VMRLKAAR-QSVYEEKLKQFEERLAEE--RHNRLEE--RKRQRKEERRITYYREKEEEEQ 815

Query: 339 EMKQNEL--------NALKATKASDLAHLQDLAKMIREYEQVIIEDRIE-KERSKKKVKQ 389
              + ++         A +A +  +L   Q+  K + E E+   +  +E +ER +++ ++
Sbjct: 816 RRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEE 875

Query: 390 DLLELKSVIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSKG-------KGKGKDKRRGKK 442
             L   S+ +  + W      R+  G      + DS+  +G       +G+G+D+ R  +
Sbjct: 876 RRLGDSSLSRKDSRWGD----RDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHR 931

Query: 443 K 443
           +
Sbjct: 932 R 932


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 56/242 (23%), Positives = 117/242 (48%), Gaps = 30/242 (12%)

Query: 183  IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQ 242
            IK L  SA     +  + +E +      D +A+ E  RK++      L+  K + Q +VQ
Sbjct: 837  IKPLLKSAETEKEMATMKEEFQKTK---DELAKSEAKRKELEEKLVTLVQEKNDLQLQVQ 893

Query: 243  SQNEYIANLKDQLQEM-KAKSNLENRYMKT------NTELQIAQTQKK------CNRTE- 288
            +++E + + +++  ++ KAK  LE +  +         E+    T KK      C+  + 
Sbjct: 894  AESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 953

Query: 289  -----ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDK---DTEM 340
                 EL + ++EK +  TE + +  TE    L +   KL    +   E + +   D + 
Sbjct: 954  DIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQA 1013

Query: 341  KQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIK 399
            +++++N+L  TK+     ++DL   + + +++    R++ ER+K+K++ DL L  +S++ 
Sbjct: 1014 EEDKVNSLNKTKSKLEQQVEDLESSLEQEKKL----RVDLERNKRKLEGDLKLAQESILD 1069

Query: 400  LQ 401
            L+
Sbjct: 1070 LE 1071



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 53/261 (20%), Positives = 114/261 (43%), Gaps = 18/261 (6%)

Query: 141  VEFNKMQDLVFKKPTRQTIMTT-ETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQAL 199
            +E NK ++  F K  R     T +    +   R+  +D +A+  +++ +      + Q L
Sbjct: 1162 IELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN---LQRVKQKL 1218

Query: 200  SKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
             KE+ E K+   D+ +  E   K   +L+K +    ++   E + +NE I     +L   
Sbjct: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEK-ICRTLEDQLSEARGKNEEIQRSLSELTTQ 1277

Query: 259  KAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK 318
            K++   E   +    E +      + +R+++   ++ E+L+ + EEE +    +   L+ 
Sbjct: 1278 KSRLQTEAGELSRQLE-EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS 1336

Query: 319  EQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRI 378
             +   +       E+Y+++ E K     AL    +       ++A+   +YE   I+   
Sbjct: 1337 SRHDCD----LLREQYEEEQEGKAELQRALSKANS-------EVAQWRTKYETDAIQRTE 1385

Query: 379  EKERSKKKVKQDLLELKSVIK 399
            E E +KKK+ Q L + +  ++
Sbjct: 1386 ELEEAKKKLAQRLQDSEEQVE 1406



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 65/266 (24%), Positives = 117/266 (43%), Gaps = 30/266 (11%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQ-DSATYNSLLQALSKERENKMHFY 210
            K  T +     ET+ K+  +++   +     + +LQ +    NSL +  SK  +      
Sbjct: 977  KNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLE 1036

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL---KDQLQEMKAKSNLENR 267
              + +E+K R   + L++     K++ + +++   E I +L   K QL E   K + E  
Sbjct: 1037 SSLEQEKKLR---VDLERN----KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 1089

Query: 268  YMKTNTE------LQIAQTQKKCNRTEELLVEEIE---KLRMKTEEEARTHTEIEMFLRK 318
             +++  E      LQ  +  K+     E L EEIE     R KTE++   +        +
Sbjct: 1090 QLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA-------R 1142

Query: 319  EQQKLEERLEFWMEKYDKDTEM-KQNELNALKATKASDLAHLQDLAKM--IREYEQVIIE 375
            E ++L ERLE          E+ K+ E   LK  +  + A LQ  A +  +R+     + 
Sbjct: 1143 ELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVA 1202

Query: 376  DRIEKERSKKKVKQDLLELKSVIKLQ 401
            +  E+  + ++VKQ L + KS  KL+
Sbjct: 1203 ELGEQIDNLQRVKQKLEKEKSEFKLE 1228



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/269 (18%), Positives = 112/269 (41%), Gaps = 38/269 (14%)

Query: 165  LKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQII 224
            L +I+I     +   A+T+K L+             + ++ ++H  D +  +E  ++Q+ 
Sbjct: 1623 LNEIEIQLSHANRQAAETLKHLRS---------VQGQLKDTQLHLDDALRGQEDLKEQLA 1673

Query: 225  SLQK-----------------QLINVKKEWQFEVQSQNEYIANLKDQLQEM-KAKSNLEN 266
             +++                 Q    +K  + E+   NE +  L  Q   +   K  LE 
Sbjct: 1674 IVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLET 1733

Query: 267  RYMKTNTELQIA--------QTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK 318
              M+  +E++ A        +  KK      ++ EE++K +  +    R    +E  ++ 
Sbjct: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793

Query: 319  EQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRI 378
             Q +L+E  +  ++   K  +  +  +  L+     +     +  K +R+YE+ + E   
Sbjct: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853

Query: 379  EKERSKKKV--KQDLLELKSVIKLQAWWR 405
            + E  +K V   QDL++ K  +K++++ R
Sbjct: 1854 QSEEDRKNVLRLQDLVD-KLQVKVKSYKR 1881



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 79/362 (21%), Positives = 146/362 (40%), Gaps = 59/362 (16%)

Query: 68   LEDTTDQLSILNYIMPVQYE---GRQSICVKSREMNLEGTNLDKLPMASTITKIPSPLIT 124
            LE+ +++L     +   Q E    R++  +K R  +LE   L    M + + K  +  + 
Sbjct: 1144 LEELSERLEEAGGVTSTQIELNKKREAEFLKLRR-DLEEATLQHEAMVAALRKKHADSVA 1202

Query: 125  EEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIK 184
            E G  +  ++ R +  +E  K +   FK        + E++ K + + +     + D + 
Sbjct: 1203 ELGEQIDNLQ-RVKQKLEKEKSE---FKLEIDDLSSSMESVSKSKANLEKICRTLEDQLS 1258

Query: 185  E-----------LQDSATYNSLLQA----LSKERENKMHFYDIIAREEKG-RKQIISLQK 228
            E           L +  T  S LQ     LS++ E K      ++R ++   +Q   L++
Sbjct: 1259 EARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKR 1318

Query: 229  QLIN---VKKEWQFEVQSQNEYIANLKDQ----------LQEMKAKSNLENRYMKTNTEL 275
            QL      K      +QS       L++Q          LQ   +K+N E    +T  E 
Sbjct: 1319 QLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1378

Query: 276  QIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYD 335
               Q      RTEEL  EE +K   +  +++    E         +K ++RL+  +E   
Sbjct: 1379 DAIQ------RTEEL--EEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLM 1430

Query: 336  KDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELK 395
             D E            +A+ LA   D  K  R +++V+ E + + E S+ +++  L E +
Sbjct: 1431 VDVE------------RANSLAAALD--KKQRNFDKVLAEWKTKCEESQAELEASLKESR 1476

Query: 396  SV 397
            S+
Sbjct: 1477 SL 1478


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 64/278 (23%), Positives = 135/278 (48%), Gaps = 50/278 (17%)

Query: 152 KKPTRQTIMTTETLKKIQID---RQFFSDVIADTIKELQDSATY-NSLLQALSKERENKM 207
           K+ T++T   T  LK  Q D    +   + +   I+ LQ++ T   + L+ + +E + K 
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587

Query: 208 HFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENR 267
              ++  + +K  +   +L+KQ           V+++N+YI  L+ + + +K K   E++
Sbjct: 588 D--EVKCKLDKSEENCNNLRKQ-----------VENKNKYIEELQQENKALKKKGTAESK 634

Query: 268 YMKT------NTELQIAQTQKKCNR--------------TEELLVEEIEKLRMKTEEEAR 307
            +          EL++   ++K                 +EE L+EE+EK ++  +E  +
Sbjct: 635 QLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK 694

Query: 308 THTEIEMFLRKEQQKLEERLEFWMEKYDK-----DTEM-----KQNELNALKATKASDLA 357
              EI+   + +  ++   +E    +YDK     D+E+     K+ E ++L+A+   +L+
Sbjct: 695 LQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELS 754

Query: 358 HLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELK 395
           +L+  A+++   +Q+ IE R EKE+ K++ K++   LK
Sbjct: 755 NLK--AELLSVKKQLEIE-REEKEKLKREAKENTATLK 789



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 62/328 (18%), Positives = 139/328 (42%), Gaps = 52/328 (15%)

Query: 90  QSIC--VKSREMNLEGTNLDKLPMASTITKIPSPLITEEGPNLPEIRHRGRFAVEFNKMQ 147
           ++IC   + +E  +E +N  +   +  +T+  + + +     L E+    +  +E N+ Q
Sbjct: 350 KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCS-----LEELLRTEQQRLEKNEDQ 404

Query: 148 DLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKM 207
             +     ++     E + K+  +++   + +   + E +     N   + +++E +   
Sbjct: 405 LKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464

Query: 208 HFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKS----- 262
              ++I   +   K++  L+ QL  +    Q+     ++ + +LK +L+  K K+     
Sbjct: 465 Q--ELIGLLQAREKEVHDLEIQLTAITTSEQY----YSKEVKDLKTELENEKLKNTELTS 518

Query: 263 -----NLENRYMKTNTE---LQIAQTQKKCN---RTEELLVEEIEKLRMKTEEEARTHTE 311
                +LEN+ +   T    L++   Q+  N   + EE ++++IE L+   E E +   E
Sbjct: 519 HCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQ---ETETQLRNE 575

Query: 312 IEMFLRKEQQKLEE-------------RLEFWMEKYDKDTEMKQNELNALKATKASDLAH 358
           +E    + +QK +E              L   +E  +K  E  Q E  ALK    ++   
Sbjct: 576 LEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE--- 632

Query: 359 LQDLAKMIREYEQVIIEDRIEKERSKKK 386
               +K +  YE  + +  +E E +K+K
Sbjct: 633 ----SKQLNVYEIKVNKLELELESAKQK 656



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 54/267 (20%), Positives = 103/267 (38%), Gaps = 37/267 (13%)

Query: 167 KIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGR------ 220
           K++ D +    +  +  KE+ D     SLL     E+ENKM     +  E + +      
Sbjct: 242 KLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEE 301

Query: 221 ---------KQIISLQ----KQLINVKKEWQFEVQSQNEYIANL-------------KDQ 254
                    KQ I  Q    K+L ++K   Q  V +Q     +L             K+ 
Sbjct: 302 KTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKET 361

Query: 255 LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEM 314
             E   K+   + ++ T  E  +   ++     ++ L +  ++L++ T E  +  +E+E 
Sbjct: 362 QMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEE 421

Query: 315 FLRKEQQKLEERLEFWMEKYDKDTEMKQNE-----LNALKATKASDLAHLQDLAKMIREY 369
             +    K  E  E      +K+T + +N+        LK T+   +  LQ   K + + 
Sbjct: 422 MTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDL 481

Query: 370 EQVIIEDRIEKERSKKKVKQDLLELKS 396
           E  +      ++   K+VK    EL++
Sbjct: 482 EIQLTAITTSEQYYSKEVKDLKTELEN 508


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 73/336 (21%), Positives = 150/336 (44%), Gaps = 43/336 (12%)

Query: 117  KIPSPLITEEGPNLPEIRHRGRFAVEF-NKMQDLV------FKKPTRQTIMTTETLKKIQ 169
            K+    I E   NL E   + +   +  NK + ++       ++  +Q     +T +K++
Sbjct: 995  KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE 1054

Query: 170  IDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDI---IAREEKGRKQIISL 226
             D    SD IA+   ++ +       +Q   KE E +     +    A++    K+I  L
Sbjct: 1055 GDSTDLSDQIAELQAQIAELK-----MQLAKKEEELQAALARVEEEAAQKNMALKKIREL 1109

Query: 227  QKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKA-KSNLENRYMKTNTELQIAQTQKKCN 285
            + Q+  ++++ + E  S+N+     +D  +E++A K+ LE+    T  + ++   ++   
Sbjct: 1110 ESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKRE--- 1166

Query: 286  RTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL 345
                   +E+  L+   EEEA+TH   E  +++ +QK  + +E   E+ ++   +K N L
Sbjct: 1167 -------QEVNILKKTLEEEAKTH---EAQIQEMRQKHSQAVEELAEQLEQTKRVKAN-L 1215

Query: 346  NALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWR 405
               K T  ++   L +  K       V+++ + + E  +KKV+  L EL+  +K      
Sbjct: 1216 EKAKQTLENERGELANEVK-------VLLQGKGDSEHKRKKVEAQLQELQ--VKFN---E 1263

Query: 406  GTMIRREIGGFKMPKDKVDSKDSKGKGKGKDKRRGK 441
            G  +R E+   K+ K +V+  +  G     D +  K
Sbjct: 1264 GERVRTELAD-KVTKLQVELDNVTGLLSQSDSKSSK 1298



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 60/264 (22%), Positives = 115/264 (43%), Gaps = 42/264 (15%)

Query: 163  ETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQ 222
            E   ++   +Q   ++  D    +++       LQA  K+ +  +   +    EE+  +Q
Sbjct: 901  ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960

Query: 223  IISLQKQLINVK----KEWQFEVQSQN---------------EYIANLKDQLQEMKAKSN 263
             + L+K     K    +E Q  ++ QN               E+  NL ++ ++ K+ + 
Sbjct: 961  KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020

Query: 264  LENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKL 323
            L+N++    T+L+      +  R EE   +E+EK R K E ++   T++   + + Q ++
Sbjct: 1021 LKNKHEAMITDLE------ERLRREEKQRQELEKTRRKLEGDS---TDLSDQIAELQAQI 1071

Query: 324  EERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI--IEDRIEKE 381
             E L+  + K       K+ EL A  A    + A      K IRE E  I  +++ +E E
Sbjct: 1072 AE-LKMQLAK-------KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123

Query: 382  RSKK----KVKQDLLELKSVIKLQ 401
            R+ +    K K+DL E    +K +
Sbjct: 1124 RASRNKAEKQKRDLGEELEALKTE 1147



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 56/290 (19%), Positives = 126/290 (43%), Gaps = 27/290 (9%)

Query: 145  KMQDLVFKKPTRQTIMT--TETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKE 202
            ++Q+L  K    + + T   + + K+Q++    + +++      Q  +  + L +  S  
Sbjct: 1253 QLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS------QSDSKSSKLTKDFSAL 1306

Query: 203  RENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKS 262
                    +++  E + +  + +  KQ+ + K  ++ +++ + E   NL+ Q+  + A+ 
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ- 1365

Query: 263  NLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQK 322
             + +   K    +   +T ++  R    L +++E L  + EE+   + ++E    + QQ+
Sbjct: 1366 -VADMKKKMEDSVGCLETAEEVKRK---LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421

Query: 323  LEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382
            L++ L       D D   +Q+  N  K  K  D    ++     +  E+    DR E E 
Sbjct: 1422 LDDLL------VDLD-HQRQSACNLEKKQKKFDQLLAEEKTISAKYAEE---RDRAEAEA 1471

Query: 383  SKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMP-KDKVDSKDSKGK 431
             +K+ K   L L   ++ +A  +   + R    F+   +D + SKD  GK
Sbjct: 1472 REKETK--ALSLARALE-EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 42/210 (20%), Positives = 90/210 (42%), Gaps = 38/210 (18%)

Query: 204  ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQE-MKAKS 262
            E K   +D +  EEK      ++  +    +   + E + +     +L   L+E M+ K+
Sbjct: 1440 EKKQKKFDQLLAEEK------TISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493

Query: 263  NLENRYMKTNTELQIAQTQK-----------KCNRTEELLVEEIEKLRMKTEEEARTHTE 311
             LE    +  TE++   + K           K  R  E  VEE++    + E+E +   +
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATED 1553

Query: 312  IEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQ 371
             ++ L    Q ++ + E  ++  D+ +E K+ +                 L + +RE E 
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQ-----------------LVRQVREMEA 1596

Query: 372  VIIEDRIEKE---RSKKKVKQDLLELKSVI 398
             + ++R ++     ++KK++ DL +L++ I
Sbjct: 1597 ELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 42/221 (19%), Positives = 89/221 (40%), Gaps = 21/221 (9%)

Query: 181  DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLI---NVKKEW 237
            D ++EL D+      + A +KE E K+   +          ++I LQ++L      K++ 
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEA---------EMIQLQEELAAAERAKRQA 1699

Query: 238  QFEVQSQNEYIANLKDQ-LQEMKAKSNLENRYMKTNTELQIAQTQ--------KKCNRTE 288
            Q E     + IAN   +    ++ K  LE R  +   EL+  Q          KK N   
Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759

Query: 289  ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNAL 348
            + +  ++   R   ++      ++E   ++ + KL+E       KY       + ++  L
Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819

Query: 349  KATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ 389
            +    ++    Q   K +R  E+ + +  ++ +  ++  +Q
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 61/273 (22%), Positives = 119/273 (43%), Gaps = 38/273 (13%)

Query: 166 KKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIIS 225
           +++Q +       +     +LQ     N L   L++++E KM       +EEK       
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW-----RQEEK------- 308

Query: 226 LQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCN 285
                    +EW+ ++Q Q E I   +++++E + K   +   M         + ++K  
Sbjct: 309 --------IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW--------EKEEKMR 352

Query: 286 RTEELLVEEIEKLR----MKTEEEARTHTEIEMFLRKEQQ--KLEERLEFWMEKYDKDTE 339
           R EE++ E+ EK+R    M  E+E +   + EM   KE++  +LEE++    EK  +  E
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEE 411

Query: 340 MKQNELNALKATKASDL-AHLQDLAKMIREYEQVIIEDRIEKERSKKKV--KQDLLELKS 396
            +Q E    +  K  +  A +    + IRE E+ I E   +  R ++K+  ++ + E + 
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471

Query: 397 VIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSK 429
             + +  WR      E       K+K+  ++ K
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/191 (19%), Positives = 88/191 (46%), Gaps = 13/191 (6%)

Query: 204 ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSN 263
           E KMH  + I  EEK ++Q   + +Q        + +++ Q E +   +++++E + K  
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQ--------EEKIREQEEKVWRQEEKIREQEEKRQ 601

Query: 264 LENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLR----MKTEEEARTHTEIEMFLRKE 319
            +   M    E +I + ++K    EE + E+ EK+R    M  E+E +   + E    +E
Sbjct: 602 EQEEKMWKQEE-KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660

Query: 320 QQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIE 379
           ++  E+    W ++     + K+      K  +  ++   Q+     +E +    E++++
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720

Query: 380 KERSKKKVKQD 390
           ++  K + +++
Sbjct: 721 EQEEKMRRQEE 731



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/245 (21%), Positives = 114/245 (46%), Gaps = 25/245 (10%)

Query: 203 RENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKS 262
           +E K+H  + I  EEK ++Q    +++    K   Q E+  Q E +   ++++++ + K 
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQE---EKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512

Query: 263 NLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKT---------EEEARTHTEIE 313
             +   ++   E +I + ++K  R EE + E+ E  R +          EEE R   E +
Sbjct: 513 WRQEEKIREQEE-KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571

Query: 314 MFLRKEQQKLEERLEFW-MEKYDKDTEMKQNELNALKATKASDLAH----LQDLAKMIRE 368
           M+ R+E++  E+  + W  E+  ++ E K+ E       +   +      +Q+  + IRE
Sbjct: 572 MW-RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630

Query: 369 YEQVIIE-DRIEKERSKKKVKQDLLELKSVIKLQ-----AWWRGTMIRREIGGFKMPKDK 422
            E+ I E + + +E+ +K  +Q+    +   K+Q      W +   IR +    +  ++K
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690

Query: 423 VDSKD 427
           +  ++
Sbjct: 691 IREQE 695



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 31/144 (21%), Positives = 74/144 (51%), Gaps = 14/144 (9%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKA 260
           +E+E K+       +EEK R+Q   +++Q   + +E + ++  Q E +   ++++QE + 
Sbjct: 615 REQEEKIQ-----EQEEKIREQEEKIREQE-EMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668

Query: 261 KSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQ 320
               +   ++   E +I + ++K    EE++ E+ EK  M  +EE     E +M  ++E+
Sbjct: 669 TMWRQEEKIREQ-EKKIREQEEKIREQEEMMQEQEEK--MWEQEEKMCEQEEKMQEQEEK 725

Query: 321 QKLEERLEFWMEKYDKDTEMKQNE 344
            + +E      + ++++  ++Q E
Sbjct: 726 MRRQEE-----KMWEQEVRLRQQE 744



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 44/236 (18%), Positives = 111/236 (47%), Gaps = 20/236 (8%)

Query: 197 QALSKERENKMHFYDIIAREEKGRKQIISLQ----KQLINVKKEWQFEVQSQNEYIANLK 252
           +AL +E E ++H   I+  ++   +  +       KQL    ++    +    ++   L+
Sbjct: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178

Query: 253 DQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRT--EELLVEEIEKLRMKTEEEARTHT 310
             L  +  +    +RY++  T+ + A + +    T  +E L E+  KL+ K +      +
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238

Query: 311 EIEMFLRKEQQKLE--------ERLEFWMEKYDKDTEMKQNELNA-LKATKASDLAHLQD 361
           EI++ +++ ++KLE        ++L+   +   K+ +    +L A ++  +  +  + Q 
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298

Query: 362 LAKMIREYEQV-IIEDRIEKERSK-KKVKQDLLELKSVIKLQ---AWWRGTMIRRE 412
             KM R+ E++   E++I+++  K ++ ++ + E +  ++ Q    W +   +RR+
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 82/429 (19%), Positives = 189/429 (44%), Gaps = 37/429 (8%)

Query: 2   EEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIP--KETDIEIIPEIPETLEPLSLP 59
           E+D LE+S    +   S   V+ T      +E+ G+   K+   E+     +  E ++  
Sbjct: 86  EDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEK 145

Query: 60  DV------------LRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLD 107
           +             LR+  V      + S+L   +   +  R    ++      +  +L+
Sbjct: 146 NYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLE 205

Query: 108 KLPMASTITKIPSPLITEEGPNLPE---IRHRGRFAVEFNKMQDLVFKKPTRQTIMTTET 164
                +TIT      + E+   L E   +    +  ++ N ++DL  K    Q ++  + 
Sbjct: 206 LY--RNTIT---DEELKEKNAELQEKLRLVESEKSEIQLN-VKDLKRKLERAQLLLPQQQ 259

Query: 165 LKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQII 224
           L   Q++       +     +LQ     N L   L++++E KM       +EEK ++Q  
Sbjct: 260 L---QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW-----RQEEKIQEQEE 311

Query: 225 SLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKC 284
            + +Q + ++++ + ++  Q E +   +++++E + K   +   ++   E +I + ++K 
Sbjct: 312 KMCEQELKIREQEE-KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE-KIREQEEKM 369

Query: 285 NRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNE 344
            R EE + E+ EK++ + EE  R   +I     K Q+K+  + +   E+ +K  E  Q E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE--QEE 427

Query: 345 LNALKATKASDLAH-LQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAW 403
               +  K  +L   +QD  + +RE E+ + E+  + +  ++K+++   +++   + + W
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTW 486

Query: 404 WRGTMIRRE 412
            +  ++++E
Sbjct: 487 RQEKLLKQE 495



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/209 (22%), Positives = 100/209 (47%), Gaps = 39/209 (18%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE--VQSQNEYIANLKDQL--Q 256
           +E+E+KM       +EEK R+Q   +++Q    +K W+ E  ++ Q+E I   ++++  Q
Sbjct: 342 REQEDKMW-----RQEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEEEMWRQ 393

Query: 257 EMKAKSNLENRYMKT---------------NTELQIAQTQKKCNRTEELLVEEIEKLRMK 301
           E K +   E R  K                  E ++ + ++K    EE++ ++ EKLR  
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR-- 451

Query: 302 TEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQD 361
                    E+E  +++E++K++E+ E    + +K  E ++      K  K  +    Q+
Sbjct: 452 ---------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502

Query: 362 LAKMIREYEQVIIEDRIEKERSKKKVKQD 390
             KM R+ E++  ++   +E+ +K  +Q+
Sbjct: 503 -EKMWRQEEKMWEQEEKMQEQEEKMQRQE 530



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 36/157 (22%), Positives = 77/157 (49%), Gaps = 13/157 (8%)

Query: 201 KERENKMHFYDIIARE--EKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
           ++R+ KM   +   RE  EK R+Q   + +Q   ++ E +  +Q Q E +  +++++QE 
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR-ELEEMMQDQEEKLREVEEKMQEE 460

Query: 259 KAK-----SNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKL----RMKTEEEARTH 309
           + K       ++ +  K   + +    Q+K  + EE + E+ EK+        E+E +  
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520

Query: 310 TEIEMFLRKEQQKLEERLEFW-MEKYDKDTEMKQNEL 345
            + E   R+E++  E+ +  W  E+  ++ E++  EL
Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 82/429 (19%), Positives = 189/429 (44%), Gaps = 37/429 (8%)

Query: 2   EEDSLEDSNLPPKVWHSEMTVSVTGEPPSTVEEEGIP--KETDIEIIPEIPETLEPLSLP 59
           E+D LE+S    +   S   V+ T      +E+ G+   K+   E+     +  E ++  
Sbjct: 86  EDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEK 145

Query: 60  DV------------LRISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLD 107
           +             LR+  V      + S+L   +   +  R    ++      +  +L+
Sbjct: 146 NYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLE 205

Query: 108 KLPMASTITKIPSPLITEEGPNLPE---IRHRGRFAVEFNKMQDLVFKKPTRQTIMTTET 164
                +TIT      + E+   L E   +    +  ++ N ++DL  K    Q ++  + 
Sbjct: 206 LY--RNTIT---DEELKEKNAELQEKLRLVESEKSEIQLN-VKDLKRKLERAQLLLPQQQ 259

Query: 165 LKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQII 224
           L   Q++       +     +LQ     N L   L++++E KM       +EEK ++Q  
Sbjct: 260 L---QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW-----RQEEKIQEQEE 311

Query: 225 SLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKC 284
            + +Q + ++++ + ++  Q E +   +++++E + K   +   ++   E +I + ++K 
Sbjct: 312 KMCEQELKIREQEE-KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE-KIREQEEKM 369

Query: 285 NRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNE 344
            R EE + E+ EK++ + EE  R   +I     K Q+K+  + +   E+ +K  E  Q E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE--QEE 427

Query: 345 LNALKATKASDLAH-LQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAW 403
               +  K  +L   +QD  + +RE E+ + E+  + +  ++K+++   +++   + + W
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTW 486

Query: 404 WRGTMIRRE 412
            +  ++++E
Sbjct: 487 RQEKLLKQE 495



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/209 (22%), Positives = 100/209 (47%), Gaps = 39/209 (18%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE--VQSQNEYIANLKDQL--Q 256
           +E+E+KM       +EEK R+Q   +++Q    +K W+ E  ++ Q+E I   ++++  Q
Sbjct: 342 REQEDKMW-----RQEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEEEMWRQ 393

Query: 257 EMKAKSNLENRYMKT---------------NTELQIAQTQKKCNRTEELLVEEIEKLRMK 301
           E K +   E R  K                  E ++ + ++K    EE++ ++ EKLR  
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR-- 451

Query: 302 TEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQD 361
                    E+E  +++E++K++E+ E    + +K  E ++      K  K  +    Q+
Sbjct: 452 ---------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502

Query: 362 LAKMIREYEQVIIEDRIEKERSKKKVKQD 390
             KM R+ E++  ++   +E+ +K  +Q+
Sbjct: 503 -EKMWRQEEKMWEQEEKMQEQEEKMQRQE 530



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 36/157 (22%), Positives = 77/157 (49%), Gaps = 13/157 (8%)

Query: 201 KERENKMHFYDIIARE--EKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
           ++R+ KM   +   RE  EK R+Q   + +Q   ++ E +  +Q Q E +  +++++QE 
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR-ELEEMMQDQEEKLREVEEKMQEE 460

Query: 259 KAK-----SNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKL----RMKTEEEARTH 309
           + K       ++ +  K   + +    Q+K  + EE + E+ EK+        E+E +  
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520

Query: 310 TEIEMFLRKEQQKLEERLEFW-MEKYDKDTEMKQNEL 345
            + E   R+E++  E+ +  W  E+  ++ E++  EL
Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 69/257 (26%), Positives = 115/257 (44%), Gaps = 33/257 (12%)

Query: 145 KMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSL---LQALSK 201
           K Q+L  K  TR+     +   K+ +++     +     KE Q+S     L    +A+  
Sbjct: 492 KEQELTKKLQTREREFQEQM--KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT 549

Query: 202 ERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAK 261
           E ENK+   D+    E  R +I+ L+  L       +  +Q       +L   L+  K K
Sbjct: 550 ESENKLR--DLQQEAETYRTRILELESSL-------EKSLQENKNQSKDLAVHLEAEKNK 600

Query: 262 SNLENRYM--KTNTELQIAQTQKKCNRTEELLV------EEIEKLRMKTEEEARTHTEIE 313
            N E   M  K  TEL+  + Q+    TE+L V       E+EKLR K E+E  T  + +
Sbjct: 601 HNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDK 660

Query: 314 MFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI 373
             +   Q  +EE  E  +EK D    +KQ EL +L    +S+L+ +      + E E  +
Sbjct: 661 EIIF--QAHIEEMNEKTLEKLD----VKQTELESL----SSELSEVLKARHKLEE-ELSV 709

Query: 374 IEDRIEKERSKKKVKQD 390
           ++D+ +K + + + K D
Sbjct: 710 LKDQTDKMKQELEAKMD 726



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 55/233 (23%), Positives = 110/233 (47%), Gaps = 31/233 (13%)

Query: 176  SDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGR--KQIISLQKQLINV 233
            ++++ +  +E   S      L +  + + N + F    A  EK +  K+I+ LQK L  +
Sbjct: 1897 TELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML 1956

Query: 234  KKEWQFEVQS-QNEYIANLKDQLQEMKAKSNLENRYMKTNTEL---------QIAQTQKK 283
            +KE Q E++  + EY     DQ +E K K   E+  +K N+ L         Q+AQ +++
Sbjct: 1957 RKEHQQELEILKKEY-----DQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQE 2011

Query: 284  CNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQN 343
               T   + E I K +    E   +H E    L K+  + ++ L+   ++Y++  + ++ 
Sbjct: 2012 LEMT---IKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREE 2068

Query: 344  ELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKS 396
            E+ A    K  DL     L ++ ++Y+Q     ++E+E +       ++EL++
Sbjct: 2069 EMTA----KVRDLQ--TQLEELQKKYQQ-----KLEQEENPGNDNVTIMELQT 2110



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 44/193 (22%), Positives = 93/193 (48%), Gaps = 28/193 (14%)

Query: 226 LQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCN 285
           L ++L  ++K     +  + + I  L+D      AK+ +E   ++ +  + IA+T+++ +
Sbjct: 323 LDERLQELEKIKDLHMAEKTKLITQLRD------AKNLIEQ--LEQDKGMVIAETKRQMH 374

Query: 286 RTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL 345
            T E+  EEI +LR + ++      E+     +EQ++  ER  F  E+ +K     Q   
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQGEEL-----REQKEKSERAAF--EELEKALSTAQKTE 427

Query: 346 NALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLEL------KSVIK 399
            A +  KA       ++ + I+  E+   E+RI  ++   +VKQ+++++      + + K
Sbjct: 428 EARRKLKA-------EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAK 480

Query: 400 LQAWWRGTMIRRE 412
           LQ      + R+E
Sbjct: 481 LQKLHEKELARKE 493



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/302 (18%), Positives = 138/302 (45%), Gaps = 24/302 (7%)

Query: 136  RGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA-DTIKELQDSATYNS 194
            +G    + +KM+    K+   +T + ++T + ++++       I  +++ E+  +  YN 
Sbjct: 1499 KGEMEDDKSKMEK---KESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN--YNQ 1553

Query: 195  LLQALSKERENKMHFYDIIAREEKGR-----KQIISLQKQLINVKKEWQFEVQSQNEYIA 249
                  KE   K+  +  +  E+  R     ++I++L+ Q+ ++K E + + +       
Sbjct: 1554 QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNL 1613

Query: 250  NLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTH 309
            ++K + +E+KA   LE+R +++ +  ++A+ ++K  +    + +++     + EE+ +  
Sbjct: 1614 SVKSKEEELKA---LEDR-LESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKG 1669

Query: 310  TEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL--------NALKATKASDLAHLQD 361
            TE  +     + +  ER    +E+  K  E  Q+E         N    T+  +      
Sbjct: 1670 TESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1729

Query: 362  LAKMIREYEQVIIEDRIEKERSKKKVKQDLLE-LKSVIKLQAWWRGTMIRREIGGFKMPK 420
            + K   E   V+  +  EKE+  ++V Q+  E + S  +++  ++  +I+ E    K  +
Sbjct: 1730 VQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHE 1789

Query: 421  DK 422
            D+
Sbjct: 1790 DQ 1791



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 65/333 (19%), Positives = 139/333 (41%), Gaps = 74/333 (22%)

Query: 146 MQDLVFKKPTRQTIMTT---ETLKKIQIDRQFFS-------DVIADTIKELQDSATYNSL 195
           +++ +F+  ++++++ T   E+L ++ +D    S       D  A+ +    DS     L
Sbjct: 80  IKESLFRSSSKESLVRTSSRESLNRLDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQL 139

Query: 196 LQALSKERENKMHF----------YDIIAREEKGRKQIISLQ-----KQLINVKKEWQFE 240
           +Q L +   +   +          Y ++ RE+K  + I+S       +++  +++E Q +
Sbjct: 140 IQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMD 199

Query: 241 VQS----QNEYIANLKD--------QLQEMKAKSNLENRYMKTNTELQIAQ--------- 279
            Q+    Q E+ A+L++        Q Q    K  L N  M  +    + Q         
Sbjct: 200 QQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFT 259

Query: 280 ----------------TQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKL 323
                           T  K   T +  V+  E L  + +E  ++H E    L  E++ L
Sbjct: 260 KEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEAL 319

Query: 324 EERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQ----VIIEDRIE 379
           +E+L+  +++ +K  ++         A K   +  L+D   +I + EQ    VI E + +
Sbjct: 320 QEQLDERLQELEKIKDLHM-------AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQ 372

Query: 380 KERSKKKVKQDLLELKSVIKLQAWWRGTMIRRE 412
              + +  ++++ +L+S IK Q   +G  +R +
Sbjct: 373 MHETLEMKEEEIAQLRSRIK-QMTTQGEELREQ 404



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/256 (21%), Positives = 122/256 (47%), Gaps = 23/256 (8%)

Query: 163  ETLKKIQIDRQFFSDVIA-DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRK 221
            E L ++Q D  F  D ++ + I  L+    +++      K+ +++   +    +E + + 
Sbjct: 1409 ELLDQVQ-DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQL 1467

Query: 222  QIISLQK----QLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQI 277
            ++ S +     + IN+ KE   E+  QN+    LK ++++ K+K   +   ++T  + Q 
Sbjct: 1468 ELKSKEAYEKDEQINLLKE---ELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQT 1524

Query: 278  AQTQKKCNRTEELLVE---EIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKY 334
            A+  +  +   +  +E     E L+   +++   H E+   L+  Q+  EE+     E  
Sbjct: 1525 ARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE 1584

Query: 335  DKDTEMKQNELNALKA---TKASDLAHLQDLAKMIREYEQVIIEDRIEKERS------KK 385
            +K   + +N++ ++KA   TK  +L H+ +L+   +E E   +EDR+E E +      K+
Sbjct: 1585 EKILTL-ENQVYSMKAELETKKKELEHV-NLSVKSKEEELKALEDRLESESAAKLAELKR 1642

Query: 386  KVKQDLLELKSVIKLQ 401
            K +Q +  +K  +  Q
Sbjct: 1643 KAEQKIAAIKKQLLSQ 1658



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/245 (21%), Positives = 112/245 (45%), Gaps = 53/245 (21%)

Query: 192  YNSLLQALSKERENKMHFY----DIIAREEKGRKQIISLQKQLINVKK--------EWQF 239
            Y S L+  +KE+E          ++I +  +G+K+ I +  Q ++ K+        E++ 
Sbjct: 888  YESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 947

Query: 240  EVQSQNEYIANLKDQLQEMKA--KSNLENRYMKT-----NTELQIAQTQKKCNR------ 286
            + ++Q + +  +K + +EM+   K  L ++  K      NT L+++Q +K+ N       
Sbjct: 948  KFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMA 1007

Query: 287  --TEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNE 344
                  + + + +L    +E+  + TE+       +++L + +  W +K ++  E  Q E
Sbjct: 1008 QANSAGISDAVSRLETNQKEQIESLTEVH------RRELNDVISIWEKKLNQQAEELQ-E 1060

Query: 345  LNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKK--------VKQD--LLEL 394
            ++ ++         LQ+  + + E +Q I+    EKE   K+        VKQD  L EL
Sbjct: 1061 IHEIQ---------LQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1111

Query: 395  KSVIK 399
            +  +K
Sbjct: 1112 QEQLK 1116



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 15/191 (7%)

Query: 216  EEKGRKQIISLQKQLINVKKEWQFEVQSQNE-YIANLKDQLQEMKAKSNLENRYMKT--- 271
            + K  ++I +++KQL++  +E + + +   E +++ L  +LQE + + ++    +K+   
Sbjct: 1641 KRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1700

Query: 272  --NTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEA-----RTHTEIEMFLRKEQQKLE 324
              +  L + ++ K      E    + +    KT EE      R  TE E  L++  Q+ E
Sbjct: 1701 SQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKE 1760

Query: 325  ERLE--FWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382
            E +   F M    ++  +K     A +    S + HLQ+  +   +   +I+   +EKE 
Sbjct: 1761 ETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEG 1820

Query: 383  SKKKV--KQDL 391
             K  +  KQ+L
Sbjct: 1821 GKNNIQAKQNL 1831



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 64/273 (23%), Positives = 114/273 (41%), Gaps = 60/273 (21%)

Query: 182  TIKELQD-----SATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKE 236
            T+ ELQ+     SA  NSL Q    E + K H   +     K  K+   LQ+QL+ +K  
Sbjct: 1107 TLNELQEQLKQKSAHVNSLAQ---DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKML 1163

Query: 237  WQFEVQSQNEYIANLK---DQLQEMKAKSNLENR--------YMKTNTELQIAQTQKKCN 285
             + + +  +E  + LK   ++ Q +K+     N+        + K + EL I Q    C 
Sbjct: 1164 AEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAI-QLDICCK 1222

Query: 286  RTEELLVEEIEKL--------------------RMKTEEEAR-----THTEIEMFLRKEQ 320
            +TE LL  +  +L                    R    +EA      T +E+E  LR+  
Sbjct: 1223 KTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT 1282

Query: 321  QKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIE----- 375
            ++ +  L    ++     E K+N++ ++KA   S +   + L K     +Q   E     
Sbjct: 1283 EE-QNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCI 1341

Query: 376  DRIEKERS---------KKKVKQDLLELKSVIK 399
             +++KE S         K+++K+  +E+ S+ K
Sbjct: 1342 TQLKKELSENINAVTLMKEELKEKKVEISSLSK 1374



 Score = 36.2 bits (82), Expect = 0.061
 Identities = 38/175 (21%), Positives = 84/175 (48%), Gaps = 15/175 (8%)

Query: 224  ISLQKQLINV---KKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQT 280
            I L KQ+  V   KK+   E+ +    + +L  QL++  ++   + + +    E ++   
Sbjct: 836  ILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG 895

Query: 281  QKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEM 340
             K+  +T+++LVE+   +    E + +   EIE+  +K   K E+ +    E+Y+   + 
Sbjct: 896  NKEQEQTKQILVEKENMILQMREGQKK---EIEILTQKLSAK-EDSIHILNEEYETKFKN 951

Query: 341  KQNELNALKATKASDLAH------LQDLAKMIREYEQVIIE-DRIEKERSKKKVK 388
            ++ ++  +K  KA ++        L   AK+ +E E   +E  + EK+ + K ++
Sbjct: 952  QEKKMEKVK-QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLE 1005



 Score = 35.8 bits (81), Expect = 0.080
 Identities = 68/267 (25%), Positives = 114/267 (42%), Gaps = 60/267 (22%)

Query: 184 KELQDSATYNSLLQALSK-------ERENKMHFYDIIAREEK-GRKQIISLQKQLINVKK 235
           KE  + A +  L +ALS         R+ K    + I   EK   ++ ISLQ++L  VK+
Sbjct: 405 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQ 464

Query: 236 E-WQFEVQSQNEYIANLKD--------QLQEMKAKSNLENRYMKTNTELQIAQTQ----- 281
           E      +S  E IA L+         + QE+  K     R  +   ++ + ++Q     
Sbjct: 465 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 524

Query: 282 --KKCNRTEELLVEEIE------------KLRMKTEEEARTH----TEIEMFLRKEQQK- 322
             ++  + E L +EE+E            KLR   ++EA T+     E+E  L K  Q+ 
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKSLQEN 583

Query: 323 ------LEERLEFWMEKYDKD----TEMKQNELNALKATKASDLAHLQDLAKMIREYEQV 372
                 L   LE    K++K+     E  + EL +LK     D    + L  + ++Y   
Sbjct: 584 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK--HQQDALWTEKLQVLKQQY--- 638

Query: 373 IIEDRIEKERSK-KKVKQDLLELKSVI 398
             +  +EK R K ++ K+ LL+ K +I
Sbjct: 639 --QTEMEKLREKCEQEKETLLKDKEII 663



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 45/231 (19%), Positives = 101/231 (43%), Gaps = 29/231 (12%)

Query: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGR----KQIISLQKQLINVKKE 236
           +++K  QD A +   LQ L ++ + +M        +EK      K+II  Q  +  + ++
Sbjct: 617 ESLKHQQD-ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII-FQAHIEEMNEK 674

Query: 237 WQFEVQSQNEYIANLKDQLQE-MKAKSNLENRYM-------KTNTELQIAQTQKKCNRTE 288
              ++  +   + +L  +L E +KA+  LE           K   EL+    ++K +  +
Sbjct: 675 TLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 734

Query: 289 EL--LVEEIEKLRMKTEEEARTH-TEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL 345
           ++  +++E E    +TE+  +    ++E+ L++  + L+E  +  +E  + D +  + EL
Sbjct: 735 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEH-QAHVENLEADIKRSEGEL 793

Query: 346 NALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKS 396
               A              + + Y+    E     E    +++Q LL+L++
Sbjct: 794 QQASAK-----------LDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLET 833


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 71/366 (19%), Positives = 171/366 (46%), Gaps = 33/366 (9%)

Query: 68   LEDTTDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPSPLITEEG 127
            L++T++Q  IL + +  Q +  Q   +++ E+    T L+K      ++K+   L  +  
Sbjct: 897  LQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEK-----QVSKLEQELQKQRE 951

Query: 128  PNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKEL- 186
             +  ++R             DL  +K     I  T T ++++I+   + + ++   KE+ 
Sbjct: 952  SSAEKLRKMEEKCESAAHEADLKRQK----VIELTGTARQVKIEMDQYKEELSKMEKEIM 1007

Query: 187  ------QDSATYNSLLQALSKERENKMHFYDIIARE-EKGRKQIISLQKQLINVKKEWQF 239
                  ++ A + S L  +  + + ++       +E EK +    +   + +  ++  + 
Sbjct: 1008 HLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET 1067

Query: 240  EVQSQNEYIANLKDQLQEM-----KAKSNLENRYMKTN---TELQIAQTQKKCNRTEELL 291
            E+Q+ +  + +   QLQE+     KA+ +LE +Y        EL+  + + +  + E L 
Sbjct: 1068 ELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLE 1127

Query: 292  VEEIEKLR-MKTEEEARTHTEIEMFLRKEQQKLEER---LEFWMEKYDKDTEMKQNELNA 347
            +++  K R  + ++ A   T ++M +R+ + ++E++   LE  +EK + + +    ++ +
Sbjct: 1128 MDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIES 1187

Query: 348  LKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGT 407
            L     +    L++   ++ + EQ I + + E ER+++++K    E++SV+K Q  +  T
Sbjct: 1188 LNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMK----EMESVMKEQEQYIAT 1243

Query: 408  MIRREI 413
              +  I
Sbjct: 1244 QYKEAI 1249



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 68/270 (25%), Positives = 123/270 (45%), Gaps = 45/270 (16%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATY-----NSLL---QALS--- 200
            K   RQ     + L+K Q+  +     I D   EL++           LL   QAL    
Sbjct: 1077 KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERN 1136

Query: 201  ---KERENKMHFYDIIAREEKGR--KQIISLQKQLINVK---KEWQFEVQSQNEYIANLK 252
               K+R  ++   D+  RE +G   ++II L+  L   +   KE   +++S N+ + N K
Sbjct: 1137 WELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAK 1196

Query: 253  DQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEI--------------EKL 298
            +QL+E K    L+N    +  + +I +TQ++    E ++ E+               ++L
Sbjct: 1197 EQLRE-KEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQEL 1255

Query: 299  RMKTEEEARTHTEI------EMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL-NALKAT 351
            R+  E+   +HTE+      ++  ++E ++L   LE  M++  K+ +   N L   L A+
Sbjct: 1256 RLTREQVQNSHTELAEARHQQVQAQREIERLSSELED-MKQLSKEKDAHGNHLAEELGAS 1314

Query: 352  KASDLAHLQDLAKMIREYEQVIIEDRIEKE 381
            K  + AHL+  A+M  E +++  E    KE
Sbjct: 1315 KVRE-AHLE--ARMQAEIKKLSAEVESLKE 1341



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 54/239 (22%), Positives = 104/239 (43%), Gaps = 23/239 (9%)

Query: 160  MTTETLKKIQIDRQFFSDVIADTIKELQ-DSATY---NSLLQALSKERENKMHFYDIIAR 215
            M  E +KK +  +   + V  +TIK  Q DSA       L+  L++   NK  F   +  
Sbjct: 819  MKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQL-- 876

Query: 216  EEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK---TN 272
             +K  +++  LQK+L  +K     E   QN  + +   Q Q+M  +  + N  ++   T 
Sbjct: 877  -KKKSEEVYCLQKEL-KIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTK 934

Query: 273  TELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK--EQQKLEERLEFW 330
             E Q+++ +++  +  E      EKLR   E+      E ++  +K  E      +++  
Sbjct: 935  LEKQVSKLEQELQKQRE---SSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIE 991

Query: 331  MEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ 389
            M++Y ++    + E+  LK    +   HL  L       + ++ + + E E+    VK+
Sbjct: 992  MDQYKEELSKMEKEIMHLKRDGENKAMHLSQL-------DMILDQTKTELEKKTNAVKE 1043



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 35/155 (22%), Positives = 76/155 (49%), Gaps = 7/155 (4%)

Query: 240 EVQSQNEYIANLKDQLQE-MKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKL 298
           E+  +   +  L+ QL+E + A S++  +  +   EL   +  +K    E  +  E EK+
Sbjct: 691 EMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELM--EKNEKIRSLETNINTEHEKI 748

Query: 299 RMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAH 358
            +  E+  + H E      KE +K  ERLE  +EK D+  + ++  ++ L+        H
Sbjct: 749 CLAFEKAKKIHLE----QHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHH 804

Query: 359 LQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLE 393
           L+ L +++ E +  + ++ ++K+ + K ++  + E
Sbjct: 805 LESLDRLLTESKGEMKKENMKKDEALKALQNQVSE 839



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 49/227 (21%), Positives = 101/227 (44%), Gaps = 30/227 (13%)

Query: 201 KERENKMHFYD--IIAREE---KGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKD-- 253
           +E ENK+      +I +E+   + +++ I L+  L+   K+ +   + +NE + N ++  
Sbjct: 308 REAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELS 367

Query: 254 ------------QLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMK 301
                       +L++++A+  +  R + TN E +  + Q++C   +  L    EKLR  
Sbjct: 368 KAFQQYKKKVAEKLEKVQAEEEILERNL-TNCEKENKRLQERCGLYKSELEILKEKLRQL 426

Query: 302 TEEEARTHTEIEMFLRKEQQKLEE---------RLEFWMEKYDKDTEMKQNELNALKATK 352
            EE      ++ +   K  + + +         +LE  +E  D+    K + +N  +  K
Sbjct: 427 KEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELK 486

Query: 353 ASDLAHLQDLAKMIREYEQVIIEDR-IEKERSKKKVKQDLLELKSVI 398
               A  + L    +E E   +E R +EK  S+  +K++L   KS +
Sbjct: 487 VRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYL 533


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 53/255 (20%), Positives = 118/255 (46%), Gaps = 19/255 (7%)

Query: 138 RFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQ 197
           +F +E+ ++   V KK            +++  +    S  +A  +K  QD  T    + 
Sbjct: 38  KFRIEYERLH-AVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQT---TIA 93

Query: 198 ALSKERENKMHFYD-IIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQ 256
           +L KE E      D    +E+K ++ I++L+++++N+ K  +       +  +N++D L+
Sbjct: 94  SLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLR 153

Query: 257 EMKAKSNLENRYMKTNTELQ--IAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEM 314
             +  +   ++ +    +L+  +AQT ++   TE    E    +    +E  +   E   
Sbjct: 154 FKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASR 213

Query: 315 FLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVII 374
             RK     +E+LE  +++   D + +Q E+ AL+        ++Q   + +++ EQ + 
Sbjct: 214 EFRK-----KEKLEKELKQIQADMDSRQTEIKALQ-------QYVQKSKEELQKLEQQLK 261

Query: 375 EDRIEKERSKKKVKQ 389
           E +I  ER+ K+++Q
Sbjct: 262 EQKILNERAAKELEQ 276



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 61/227 (26%), Positives = 101/227 (44%), Gaps = 34/227 (14%)

Query: 196 LQALSKERENKMHFYDIIARE-----EKGRKQIISLQKQLINVKKEWQFEVQSQNEYIAN 250
           ++A  K+ E      D + RE     +   K + + QKQ   VK   Q +   + E I N
Sbjct: 365 VEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGE-IQN 423

Query: 251 LKDQLQEM-KAKSNLE---NRYMKTNTELQIAQTQKKCNRTEELLVEEIE--KLRMKTEE 304
            KD+ Q+  K   +LE   +RY+   ++L    TQK     E++ V E +    R K  E
Sbjct: 424 YKDEAQKQRKIIFHLEKERDRYINQASDL----TQKVLMNMEDIKVRETQIFDYRKKIAE 479

Query: 305 EARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK 364
                +EI++   K+QQ L E +      Y K+    Q+E+  +K      +  + +L +
Sbjct: 480 -----SEIKL---KQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKE 531

Query: 365 MIREYEQVII-----EDRIEKERSK-----KKVKQDLLELKSVIKLQ 401
            I   E  ++     + RIEKE+       +K++Q  LE K  I+ Q
Sbjct: 532 DISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQ 578



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 54/292 (18%), Positives = 119/292 (40%), Gaps = 55/292 (18%)

Query: 123 ITEEGPNLPEIRHRG-----RFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSD 177
           + E+G  L   +H       RF  E  K +D +  +  +      +T ++ Q        
Sbjct: 133 LVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQ-------- 184

Query: 178 VIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEW 237
              +T +  +++    S  Q   ++R+N+       +RE + ++++    KQ+       
Sbjct: 185 ---ETERSKEEAEHAISQFQQEIQQRQNEA------SREFRKKEKLEKELKQIQADMDSR 235

Query: 238 QFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEK 297
           Q E+++  +Y+   K++LQ+++                Q  + QK  N      +E+ + 
Sbjct: 236 QTEIKALQQYVQKSKEELQKLE----------------QQLKEQKILNERAAKELEQFQM 279

Query: 298 LRMKTEEEARTHTEI-EMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASD- 355
              K ++E   H+ + E   ++ QQK        +E   K+ E+ Q  L+  K  K  + 
Sbjct: 280 RNAKLQQENEQHSLVCEQLSQENQQKA-------LELKAKEEEVHQMRLDIGKLNKIREQ 332

Query: 356 ----LAHLQDLAKMIREYEQVIIEDRI----EKERSKKKVKQDLLELKSVIK 399
               L H +D    + ++++ +    +    E E SKK+ + D   +  +++
Sbjct: 333 IHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLR 384



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 24/114 (21%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 157 QTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSK----ERENKMHFYDI 212
           + I    TL+K  I +    +V+   +   +    Y  L   L++    E   ++  Y  
Sbjct: 725 ELIQKIHTLQKRLISKT--EEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLYRR 782

Query: 213 IAREEKGRKQIISLQKQLINVK-KEWQFEVQSQNEYIANLKDQLQEMKAKSNLE 265
              ++K + +++S +  +  V+ KE+++EV+     + NLK +    K K  L+
Sbjct: 783 TLHDKKQQLKVLSSELNMYEVQSKEYKYEVEKLTNELQNLKKKYLAQKRKEQLQ 836


>gi|19923981 IQ motif containing D [Homo sapiens]
          Length = 347

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 72/320 (22%), Positives = 142/320 (44%), Gaps = 52/320 (16%)

Query: 163 ETLKKIQIDRQFFSDVIADTIKELQDSATYN----SLLQALSKERENK--MHFYDII--A 214
           + LK + + R   + + A  I  + D A Y     +LL  ++  RE+   M   D++   
Sbjct: 32  DPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGEDVMRAV 91

Query: 215 REEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSN----------- 263
           RE +   Q++ L+      +KE Q + Q + E    L+D+L  ++ + +           
Sbjct: 92  REHEDLCQVL-LENVRCLKEKERQLQEQKEAEEEGWLRDRLLSIELQKSSLSPLMQQIKD 150

Query: 264 ---------LEN----RYMKTNTELQIAQTQKKCNRTEEL---LVEEIEKLRMKTEEEAR 307
                    L N    R ++  T+ + A+ Q   +   EL   L E++    M+  ++A+
Sbjct: 151 STKNVLRLLLSNPQAARLLQMQTQGRSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQ 210

Query: 308 THTEIEMFLRKEQQ---KLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK 364
              +I       QQ    LE+ L   M+  + + E++  +L+A+   +   L  L+   K
Sbjct: 211 FLQDISRQNSNNQQIIDTLEKELAERMKNRNAEEELE--DLDAVHREEKISLEELRRRHK 268

Query: 365 -MIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPKDKV 423
            ++ E+ Q+  E  I  ++  +  ++ +  +++   +QA W+G ++R            +
Sbjct: 269 VLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALWKGYLVR----------SLL 318

Query: 424 DSKDSKGKGKGKDKRRGKKK 443
            SK  +GKGK KDK +GK+K
Sbjct: 319 RSKKKRGKGKAKDKEKGKQK 338


>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
          Length = 2649

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 47/198 (23%), Positives = 97/198 (48%), Gaps = 18/198 (9%)

Query: 203  RENKMHFYDIIAREEKGRKQIISLQKQLI---NVKKEWQFEVQSQNEYIANLKDQLQEMK 259
            R    H +     E+  +++I  L++ L    N+  E++ +   QN  I N K +++ + 
Sbjct: 1626 RSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLN 1685

Query: 260  AKSNL---ENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFL 316
            A+ N    E R  +   +LQ AQ Q+  NR +++     ++L +KT EE  TH ++ +F 
Sbjct: 1686 AELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQ----DELHLKTIEEQMTHRKMVLF- 1740

Query: 317  RKEQQKLEERLEFWMEKYDKDTEMK---QNELNALKATKASDLAHLQDLAKMIREYEQVI 373
            ++E  K ++  E + +K +K  E K   +N+++ ++     D   LQ      +E  ++ 
Sbjct: 1741 QEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRL----DFVSLQQENSRAQENAKLC 1796

Query: 374  IEDRIEKERSKKKVKQDL 391
              +  E ER  ++ ++ +
Sbjct: 1797 ETNIKELERQLQQYREQM 1814



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 55/267 (20%), Positives = 121/267 (45%), Gaps = 25/267 (9%)

Query: 138  RFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQ 197
            R AVE N +    F+    +   T  TL+    D     D+  + +++ +     N L++
Sbjct: 1228 RAAVEENLLN---FRNQLEENTFTRRTLE----DHLKRKDLSLNDLEQQK-----NKLME 1275

Query: 198  ALSKERENKMHFYDIIAREEKGRKQIISLQKQLIN--VKKEWQFEVQSQNEYIANLKDQL 255
             L ++R+N+     +I + EK     ++ QKQ+    +K++ + E++++ + I  ++   
Sbjct: 1276 ELRRKRDNEEELLKLIKQMEKD----LAFQKQVAEKQLKEKQKIELEARRK-ITEIQYTC 1330

Query: 256  QE--MKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIE 313
            +E  +      +    +  T LQ    ++K    ++  V+E+     K E++ R  T   
Sbjct: 1331 RENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQ-VDELTAANRKAEQDMRELTYEL 1389

Query: 314  MFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI 373
              L+ E+   EE+     +K D+     +     L+    ++  + Q L ++ R+  Q  
Sbjct: 1390 NALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTT 1449

Query: 374  --IEDRIEKERSKKKVKQDL-LELKSV 397
               E+ +++    KK+K++  LEL+S+
Sbjct: 1450 GKAEEAMQEASDLKKIKRNYQLELESL 1476



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 58/266 (21%), Positives = 121/266 (45%), Gaps = 33/266 (12%)

Query: 156  RQTIMTTET-LKKIQIDR-QFFSDVIADTIKELQ-DSATYNSLLQALSK---ERENKMHF 209
            +Q ++ +E  +K+ ++D  Q +++  + T+K+ +  + TY +++ +  K   +R      
Sbjct: 1007 QQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVDSQQKSPVKRRRMQSS 1066

Query: 210  YDIIAREEKGRKQ----IISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLE 265
             D+I +E    +     +++L  Q I    +    ++   E I   K+   E  A S+L 
Sbjct: 1067 ADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEE--EEIKRCKET-SEHGAYSDLL 1123

Query: 266  NRYMKTNTELQIAQTQKKCNRTEEL--LVEEIEKLRMKTEEE-ARTHTEIEMFLRKEQQK 322
             R   T     + +  K   +  EL  +V E++K + + EEE  +     E  LRK+Q+ 
Sbjct: 1124 QRQKAT-----VLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRN 1178

Query: 323  LEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382
            +E   +  ++K   ++E KQ         +  + A         RE E+V  +  IE E 
Sbjct: 1179 VE---DISLQKIRAESEAKQYRRELETIVREKEAAE--------RELERV-RQLTIEAEA 1226

Query: 383  SKKKVKQDLLELKSVIKLQAWWRGTM 408
             +  V+++LL  ++ ++   + R T+
Sbjct: 1227 KRAAVEENLLNFRNQLEENTFTRRTL 1252



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 33/157 (21%), Positives = 68/157 (43%), Gaps = 18/157 (11%)

Query: 228  KQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRT 287
            + LI+  K+W+ EV  + +    L+D+LQ+ KA   + +   KT  E  +     K    
Sbjct: 883  ENLISTLKQWRSEVDEKRQVFHALEDELQKAKA---ISDEMFKTYKERDLDFDWHK---- 935

Query: 288  EELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNA 347
                    EK     E     H +I+  LR + + + + L+++ + Y    +  Q     
Sbjct: 936  --------EKADQLVERWQNVHVQIDNRLR-DLEGIGKSLKYYRDTYHPLDDWIQQVETT 986

Query: 348  LKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSK 384
             +  + +   + + LA  + + + ++ E  IE ++SK
Sbjct: 987  QRKIQENQPENSKTLATQLNQQKMLVSE--IEMKQSK 1021



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 43/245 (17%), Positives = 98/245 (40%), Gaps = 33/245 (13%)

Query: 162 TETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSK-------------------- 201
           T+  K++ + +Q++ +++    +E Q+ + YN  +  +                      
Sbjct: 709 TQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNIRLRLENCEDRLIRQIRTPL 768

Query: 202 ERENKMHFYDIIAREEKGRKQIISLQKQL--INVKKEWQFEVQSQNEYIANLKDQLQEMK 259
           ER++       I  +EK +K++  L+  L  I  K E  F   + +  +  L+ +L  + 
Sbjct: 769 ERDDLHESVFRITEQEKLKKELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSELNVV- 827

Query: 260 AKSNLENRYMKTNT---ELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMF- 315
              N+   Y  ++T   +L+      K  +  E LV+  E    + E        IE   
Sbjct: 828 -LQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLI 886

Query: 316 --LRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLA---HLQDLAKMIREYE 370
             L++ + +++E+ + +    D+  + K       K  K  DL    H +   +++  ++
Sbjct: 887 STLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDLDFDWHKEKADQLVERWQ 946

Query: 371 QVIIE 375
            V ++
Sbjct: 947 NVHVQ 951


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 55/237 (23%), Positives = 112/237 (47%), Gaps = 43/237 (18%)

Query: 200  SKERENKM--------HFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL 251
            S ERE +M           + + + E  RK++      L+  K + Q +VQ++ + +A+ 
Sbjct: 842  SAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADA 901

Query: 252  KDQLQEM-KAKSNLE------NRYMKTNTELQIAQTQKK------CNRTE------ELLV 292
            +++  ++ K K  LE      N  ++   E+    T KK      C+  +      EL +
Sbjct: 902  EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTL 961

Query: 293  EEIEKLRMKTEEEARTHT-------EIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNEL 345
             ++EK +  TE + +  T       EI   L KE++ L+E  +  ++    D + +++++
Sbjct: 962  AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD----DLQAEEDKV 1017

Query: 346  NALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIKLQ 401
            N L   K      + DL   + + ++V    R++ ER+K+K++ DL L  +S++ L+
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKV----RMDLERAKRKLEGDLKLTQESIMDLE 1070



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 57/261 (21%), Positives = 109/261 (41%), Gaps = 18/261 (6%)

Query: 141  VEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSA-TYNSLLQAL 199
            +E NK ++  F+K  R      E   + +          AD++ EL +       + Q L
Sbjct: 1161 IEMNKKREAEFQKMRRDL---EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217

Query: 200  SKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
             KE+ E K+   D+ +  E+  K   +L+K    ++ +   E +S+ E      + L   
Sbjct: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN-EHRSKAEETQRSVNDLTSQ 1276

Query: 259  KAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK 318
            +AK   EN  +    + + A   +   R +    +++E L+ + EEE +    +   L  
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQ-LTRGKLTYTQQLEDLKRQLEEEVKAKNALAHAL-- 1333

Query: 319  EQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRI 378
              Q      +   E+Y+++TE K      L    +       ++A+   +YE   I+   
Sbjct: 1334 --QSARHDCDLLREQYEEETEAKAELQRVLSKANS-------EVAQWRTKYETDAIQRTE 1384

Query: 379  EKERSKKKVKQDLLELKSVIK 399
            E E +KKK+ Q L E +  ++
Sbjct: 1385 ELEEAKKKLAQRLQEAEEAVE 1405



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 76/370 (20%), Positives = 151/370 (40%), Gaps = 59/370 (15%)

Query: 64   ISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREM--NLEGTNLDKLPMASTITKIPSP 121
            +S  LE+ +++L        VQ E  +    + ++M  +LE   L     A+ + K  + 
Sbjct: 1139 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1198

Query: 122  LITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIAD 181
             + E G  +  ++ R +  +E  K +   FK          E + K + + +     + D
Sbjct: 1199 SVAELGEQIDNLQ-RVKQKLEKEKSE---FKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254

Query: 182  TIKE-----------LQDSATYNSLLQALSKERENKMHFYD-IIAREEKGRKQIISLQKQ 229
             + E           + D  +  + LQ  + E   ++   + +I++  +G+   ++  +Q
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGK---LTYTQQ 1311

Query: 230  LINVKKEWQFEVQSQN--------------------EYIANLKDQLQEMKAKSNLENRYM 269
            L ++K++ + EV+++N                    E     K +LQ + +K+N E    
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371

Query: 270  KTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEF 329
            +T  E    Q      RTEEL  EE +K   +  +EA    E         +K + RL+ 
Sbjct: 1372 RTKYETDAIQ------RTEEL--EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423

Query: 330  WMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ 389
             +E    D E       AL   +       ++  K++ E++Q   E + E E S+K+ + 
Sbjct: 1424 EIEDLMVDVERSNAAAAALDKKQ-------RNFDKILAEWKQKYEESQSELESSQKEARS 1476

Query: 390  ---DLLELKS 396
               +L +LK+
Sbjct: 1477 LSTELFKLKN 1486



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 59/287 (20%), Positives = 118/287 (41%), Gaps = 29/287 (10%)

Query: 160  MTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQ---ALSKERENKMH-----FYD 211
            M  E  K+++        ++ DT  +L D+   N  L+   A+ + R N +         
Sbjct: 1635 MAAEAQKQVKS----LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1690

Query: 212  IIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKT 271
            ++ + E+ RK     +++LI   +  Q  + SQN  + N K ++      S L+    + 
Sbjct: 1691 VVEQTERSRKLA---EQELIETSERVQL-LHSQNTSLINQKKKMDA--DLSQLQTEVEEA 1744

Query: 272  NTELQIAQTQ-KKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEF- 329
              E + A+ + KK      ++ EE++K +  +    R    +E  ++  Q +L+E  +  
Sbjct: 1745 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804

Query: 330  ------WMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERS 383
                   ++K +      +NEL A +   A  +  ++   + I+E      EDR    R 
Sbjct: 1805 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 1864

Query: 384  KKKVKQDLLELK-SVIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSK 429
            +  V  D L+LK    K QA          +  F+  + ++D  + +
Sbjct: 1865 QDLV--DKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER 1909



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 57/246 (23%), Positives = 104/246 (42%), Gaps = 41/246 (16%)

Query: 179  IADTIKELQDSA-TYNSLLQALSKERENKMH-FYDIIAREEKGRKQIISLQKQLINVKK- 235
            +A  ++E +++    N+   +L K +    +   D++   E+      +L K+  N  K 
Sbjct: 1393 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452

Query: 236  --EWQFEVQ-SQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKK------CNR 286
              EW+ + + SQ+E  ++ K+          L+N Y ++   L+  + + K       + 
Sbjct: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512

Query: 287  TEEL-----LVEEIEKLRMKTEEEAR----THTEIEMFLRKEQQK-LEERLEFWMEKYD- 335
            TE+L      + E+EK+R + E E         E E  L  E+ K L  +LEF   K + 
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572

Query: 336  ------KDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ 389
                  KD EM+Q + N L+   +            ++         R E  R KKK++ 
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDS------------LQTSLDAETRSRNEALRVKKKMEG 1620

Query: 390  DLLELK 395
            DL E++
Sbjct: 1621 DLNEME 1626



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 45/239 (18%), Positives = 112/239 (46%), Gaps = 27/239 (11%)

Query: 164  TLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQI 223
            TL K++ ++    + + +  +E+   A  + ++  L+KE++         A +E  ++ +
Sbjct: 960  TLAKVEKEKHATENKVKNLTEEM---AGLDEIIAKLTKEKK---------ALQEAHQQAL 1007

Query: 224  ISLQKQLINVKKEWQFEVQSQNEYIANLKDQL-QEMKAKSNLENRYMKTNTELQIAQT-- 280
              LQ +   V    + +V+ + + + +L+  L QE K + +LE    K   +L++ Q   
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQ-VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI 1066

Query: 281  ---QKKCNRTEELLVE---EIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKY 334
               +    + +E L +   E+  L  + E+E    ++++  L++ Q ++EE     +E+ 
Sbjct: 1067 MDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE-----LEEE 1121

Query: 335  DKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLE 393
             +     + ++  L++  + +L  + +  +       V IE   ++E   +K+++DL E
Sbjct: 1122 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/179 (24%), Positives = 88/179 (49%), Gaps = 10/179 (5%)

Query: 220 RKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNL--ENRYMKTNTELQI 277
           +KQI  L+ Q+++V++E +         + NLK +L E+  + N   + + +  +  L+ 
Sbjct: 141 QKQIKELRDQIVSVQEEKKILAIE----LENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQ 196

Query: 278 AQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK---EQQKLEERLEFWMEKY 334
            +  +KCNR   L VEE E++++  E E     + E F ++   EQ KL+ +    ++  
Sbjct: 197 RKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSS 256

Query: 335 DKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLE 393
             D ++ +      K T+  +   +Q   K ++E E+ +  + + KE    K + +LLE
Sbjct: 257 IPDQQLLKALDENAKLTQQLEEERIQHQQK-VKELEEQLENETLHKEIHNLKQQLELLE 314



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 183 IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINV---KKEWQF 239
           +K L ++A     L+    + + K+   +     E   K+I +L++QL  +   KKE + 
Sbjct: 263 LKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL 322

Query: 240 EVQSQNEYIANLKDQLQEMKAKSN 263
           + Q+  E   NLK  + E++ + N
Sbjct: 323 KYQNSEEKARNLKHSVDELQKRVN 346


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/179 (24%), Positives = 88/179 (49%), Gaps = 10/179 (5%)

Query: 220 RKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNL--ENRYMKTNTELQI 277
           +KQI  L+ Q+++V++E +         + NLK +L E+  + N   + + +  +  L+ 
Sbjct: 141 QKQIKELRDQIVSVQEEKKILAIE----LENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQ 196

Query: 278 AQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRK---EQQKLEERLEFWMEKY 334
            +  +KCNR   L VEE E++++  E E     + E F ++   EQ KL+ +    ++  
Sbjct: 197 RKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSS 256

Query: 335 DKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLE 393
             D ++ +      K T+  +   +Q   K ++E E+ +  + + KE    K + +LLE
Sbjct: 257 IPDQQLLKALDENAKLTQQLEEERIQHQQK-VKELEEQLENETLHKEIHNLKQQLELLE 314



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 183 IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINV---KKEWQF 239
           +K L ++A     L+    + + K+   +     E   K+I +L++QL  +   KKE + 
Sbjct: 263 LKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL 322

Query: 240 EVQSQNEYIANLKDQLQEMKAKSN 263
           + Q+  E   NLK  + E++ + N
Sbjct: 323 KYQNSEEKARNLKHSVDELQKRVN 346


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 63/250 (25%), Positives = 116/250 (46%), Gaps = 37/250 (14%)

Query: 163  ETLKK-IQIDRQFFSDV----------IADTIKEL-QDSATYNSLLQALSKERENKMHFY 210
            ETL+K +QI ++ F++           + +T+ +L Q    +N L   L K REN     
Sbjct: 801  ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN----- 855

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK 270
              +A  E   ++    ++QLI  K++ + ++    +   +   QL +M  +  L+ R ++
Sbjct: 856  --LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVE 913

Query: 271  TNTELQIAQTQKKCNRTEELLVEEIEKLRMKTE----EEARTHTEIEMFLRKEQQKLEER 326
               ELQ+  T  K N     L + IE + +K E    E A+ H E +  L ++   LE++
Sbjct: 914  ---ELQLKLT--KANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 968

Query: 327  LEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKK 386
            +E     +++  E+K     A   TK      LQ+L K + +      ED+++  R +  
Sbjct: 969  ME---TSHNQCQELKARYERATSETKTKHEEILQNLQKTLLD-----TEDKLKGAREENS 1020

Query: 387  -VKQDLLELK 395
             + Q+L EL+
Sbjct: 1021 GLLQELEELR 1030



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 20/215 (9%)

Query: 199  LSKEREN----KMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
            L+K  EN    +    D+  + E+ +++     ++    KKE + ++    + +    +Q
Sbjct: 919  LTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE---EKKELERKLSDLEKKMETSHNQ 975

Query: 255  LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEEL----------LVEEIEKLRMKTEE 304
             QE+KA+        KT  E  +   QK    TE+           L++E+E+LR K  +
Sbjct: 976  CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELR-KQAD 1034

Query: 305  EARTHTEIEMFLRKEQQKLEERLEFWMEKYD-KDTEMK-QNELNALKATKASDLAHLQDL 362
            +A+     E  ++  +Q  +E+ E      D K T  K QNEL+ LK     ++  L   
Sbjct: 1035 KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS 1094

Query: 363  AKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSV 397
             +++    Q + E R E E  K+   Q   +L ++
Sbjct: 1095 KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1129



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 42/226 (18%), Positives = 102/226 (45%), Gaps = 34/226 (15%)

Query: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240
           DT+ +LQ++      L+ L  +   +    D    + K  ++ +     L     E + E
Sbjct: 684 DTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSE 743

Query: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNT------ELQIAQTQK---KCNRTEELL 291
           ++   + +   + Q++ ++ + N E+    + T      EL++   Q+   + ++ +E L
Sbjct: 744 MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETL 803

Query: 292 VEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKAT 351
            +E++ L+ K  E +     ++  +++   KL +               K+ + N L   
Sbjct: 804 EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ---------------KEEQFNML--- 845

Query: 352 KASDLAHL-QDLAKMIREYEQVIIEDRIEKE--RSKKKVKQDLLEL 394
            +SDL  L ++LA M  ++ +   +D  E++  ++K+K++ D+ E+
Sbjct: 846 -SSDLEKLRENLADMEAKFRE---KDEREEQLIKAKEKLENDIAEI 887


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 63/250 (25%), Positives = 116/250 (46%), Gaps = 37/250 (14%)

Query: 163  ETLKK-IQIDRQFFSDV----------IADTIKEL-QDSATYNSLLQALSKERENKMHFY 210
            ETL+K +QI ++ F++           + +T+ +L Q    +N L   L K REN     
Sbjct: 836  ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN----- 890

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK 270
              +A  E   ++    ++QLI  K++ + ++    +   +   QL +M  +  L+ R ++
Sbjct: 891  --LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVE 948

Query: 271  TNTELQIAQTQKKCNRTEELLVEEIEKLRMKTE----EEARTHTEIEMFLRKEQQKLEER 326
               ELQ+  T  K N     L + IE + +K E    E A+ H E +  L ++   LE++
Sbjct: 949  ---ELQLKLT--KANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1003

Query: 327  LEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKK 386
            +E     +++  E+K     A   TK      LQ+L K + +      ED+++  R +  
Sbjct: 1004 ME---TSHNQCQELKARYERATSETKTKHEEILQNLQKTLLD-----TEDKLKGAREENS 1055

Query: 387  -VKQDLLELK 395
             + Q+L EL+
Sbjct: 1056 GLLQELEELR 1065



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 20/215 (9%)

Query: 199  LSKEREN----KMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
            L+K  EN    +    D+  + E+ +++     ++    KKE + ++    + +    +Q
Sbjct: 954  LTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE---EKKELERKLSDLEKKMETSHNQ 1010

Query: 255  LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEEL----------LVEEIEKLRMKTEE 304
             QE+KA+        KT  E  +   QK    TE+           L++E+E+LR K  +
Sbjct: 1011 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELR-KQAD 1069

Query: 305  EARTHTEIEMFLRKEQQKLEERLEFWMEKYD-KDTEMK-QNELNALKATKASDLAHLQDL 362
            +A+     E  ++  +Q  +E+ E      D K T  K QNEL+ LK     ++  L   
Sbjct: 1070 KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS 1129

Query: 363  AKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSV 397
             +++    Q + E R E E  K+   Q   +L ++
Sbjct: 1130 KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1164



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 42/226 (18%), Positives = 102/226 (45%), Gaps = 34/226 (15%)

Query: 181 DTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE 240
           DT+ +LQ++      L+ L  +   +    D    + K  ++ +     L     E + E
Sbjct: 719 DTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSE 778

Query: 241 VQSQNEYIANLKDQLQEMKAKSNLENRYMKTNT------ELQIAQTQK---KCNRTEELL 291
           ++   + +   + Q++ ++ + N E+    + T      EL++   Q+   + ++ +E L
Sbjct: 779 MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETL 838

Query: 292 VEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKAT 351
            +E++ L+ K  E +     ++  +++   KL +               K+ + N L   
Sbjct: 839 EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ---------------KEEQFNML--- 880

Query: 352 KASDLAHL-QDLAKMIREYEQVIIEDRIEKE--RSKKKVKQDLLEL 394
            +SDL  L ++LA M  ++ +   +D  E++  ++K+K++ D+ E+
Sbjct: 881 -SSDLEKLRENLADMEAKFRE---KDEREEQLIKAKEKLENDIAEI 922


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 14/203 (6%)

Query: 199  LSKERENKMH-FYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQN-EYIANLKDQLQ 256
            L +ER+ + H  Y   A +E+ RK+   LQ++   +++E + + + Q  E     ++QLQ
Sbjct: 878  LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937

Query: 257  EMKAKSNLENRYMKTNTELQIA-QTQKKCNRTEE-LLVEEIEKLR-----MKTEEEARTH 309
            + + +   E R  +   E +   +  KK  + EE LL EE EK R      K  EE    
Sbjct: 938  QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997

Query: 310  TEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREY 369
             E E  LR+E++K   R + W  +Y K  E++Q E   L+  +  +   LQ+  +  RE 
Sbjct: 998  QEEEQLLREEREK--RRRQEWERQYRKKDELQQEEEQLLREER--EKRRLQERERQYREE 1053

Query: 370  EQV-IIEDRIEKERSKKKVKQDL 391
            E++   E+++  E  + + +Q+L
Sbjct: 1054 EELQQEEEQLLGEERETRRRQEL 1076



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 42/199 (21%), Positives = 96/199 (48%), Gaps = 8/199 (4%)

Query: 197  QALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQ 256
            Q L ++  ++    + +  +E+GRK  +  +++L   ++E +F  + Q      L+ Q +
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRK-FLEEEQRLRRQERERKFLKEEQQ-----LRCQER 1404

Query: 257  EMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFL 316
            E + + + + ++ +   +L   +  +K  R EE  V   E+ R   EEE +   E     
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKF-REEEQQVRRQERERKFLEEEQQLRQERHRKF 1463

Query: 317  RKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIED 376
            R+E+Q L+ER E  + + ++D +  + E   L+  +       Q+L     E + +  E 
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEE-QQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522

Query: 377  RIEKERSKKKVKQDLLELK 395
            ++ +++ ++K  Q+  +L+
Sbjct: 1523 QLHRQQRQRKFLQEEQQLR 1541



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 48/192 (25%), Positives = 97/192 (50%), Gaps = 26/192 (13%)

Query: 215  REEKGRKQ--IISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTN 272
            RE+K R++  +   ++QL+  ++E +   + + +Y    KD+LQ+       E + ++  
Sbjct: 986  REKKYREEEELQQEEEQLLREEREKRRRQEWERQY--RKKDELQQE------EEQLLREE 1037

Query: 273  TELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWME 332
             E +  Q +++  R EE L +E E+L +  E E R   E+E   RKE++  +E  +   E
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQL-LGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096

Query: 333  KYDK------------DTEMKQNELNALKATKASDLAHLQDLAKMIREYEQV-IIEDRIE 379
            + +K            + E++Q E   L+  +  +    Q+L +  RE E+V   E+++ 
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREER--EKRRRQELERQYREEEEVQQEEEQLL 1154

Query: 380  KERSKKKVKQDL 391
            +E  +K+ +Q+L
Sbjct: 1155 REEPEKRRRQEL 1166



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 56/265 (21%), Positives = 121/265 (45%), Gaps = 16/265 (6%)

Query: 131  PEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQ--- 187
            PE R R     ++ + ++L  ++   Q +   +  ++ + +RQ+  +      K  Q   
Sbjct: 1158 PEKRRRQELERQYREEEEL--QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215

Query: 188  DSATYNSLLQALSKERENKMHFYDIIA--REEKGRKQIISLQKQLINVKKEWQFEVQSQN 245
            D    + L      E+EN +    +    RE +  +Q+   Q +    +++ Q  +  Q 
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275

Query: 246  EYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEE 305
            E     +D+ QE + +    +R+     +L+  + QK+  R +    EE + LR + EE+
Sbjct: 1276 E-----RDREQERR-RWQQRDRHFPEEEQLE-REEQKEAKRRDRKSQEEKQLLREEREEK 1328

Query: 306  ARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKM 365
             R   E +   R+E+Q L+ER E  + + ++D + ++ EL   +  +   L   Q L + 
Sbjct: 1329 RRRQ-ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR-KFLEEEQRLRRQ 1386

Query: 366  IREYEQVIIEDRIEKERSKKKVKQD 390
             RE + +  E ++  +  +++++QD
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQD 1411



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 50/218 (22%), Positives = 103/218 (47%), Gaps = 30/218 (13%)

Query: 197  QALSKERENK-MHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQL 255
            Q  ++ER+ +   F      +E+ R+Q    +K+L  +++E Q + + + + +   +D L
Sbjct: 797  QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL 856

Query: 256  QE--MKAKSNLENRYMKTNTELQIAQ------------TQKKCNRTEELLVEEIEKL--- 298
            QE   + +S  + R  K   +L+  +             Q++  + ++LL EE E+L   
Sbjct: 857  QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916

Query: 299  ---RMKTEEEARTHTEIEMFLRKEQQKLEE-----RLEFWMEKYDKDTEMKQNELNALKA 350
               + + +E+ R + E E   ++E+Q L E     R +    +Y KD +++Q E   L  
Sbjct: 917  EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL-- 974

Query: 351  TKASDLAHLQDLAKMIREYEQVIIEDR--IEKERSKKK 386
             +  +    Q+  K  RE E++  E+   + +ER K++
Sbjct: 975  GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 46/232 (19%), Positives = 109/232 (46%), Gaps = 28/232 (12%)

Query: 163  ETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQ 222
            ET ++ +++RQ+  +   + +++ ++        +   +ERE +    + + +EE+   +
Sbjct: 1069 ETRRRQELERQYRKE---EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125

Query: 223  IISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQK 282
                +++   ++++++ E + Q E    L+++  E + +  LE +Y +   ELQ      
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREE-PEKRRRQELERQY-REEEELQ------ 1177

Query: 283  KCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLE--FWMEKYDKDTEM 340
                 E+LL EE EK R + E + R   E++   RK++ + E++     W  + +K+  +
Sbjct: 1178 --QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235

Query: 341  KQN----------ELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKER 382
            + N          +   L+ ++  D    QDL  ++ E ++    DR ++ R
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE---RDREQERR 1284



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 57/278 (20%), Positives = 129/278 (46%), Gaps = 38/278 (13%)

Query: 125  EEGPNLPEIRHRGRFAVEFNKMQD-----LVFKKPTRQTIMTTETLKKIQIDRQFFSDVI 179
            EE   L + RHR +F  E   +Q+     L  ++  R+ +   + L++ + DR+F     
Sbjct: 1450 EEEQQLRQERHR-KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE--- 1505

Query: 180  ADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQF 239
                +EL+        L     E E ++H      R+++ RK +   ++Q +  ++  Q 
Sbjct: 1506 ----QELRSQEPERKFL-----EEEQQLH------RQQRQRKFL--QEEQQLRRQERGQQ 1548

Query: 240  EVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLR 299
              Q ++      ++QL++ + +  L  +  + + + ++ + + +    E   +E+ ++LR
Sbjct: 1549 RRQDRDRKFRE-EEQLRQEREEQQLSRQ--ERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605

Query: 300  MKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHL 359
             + E + +   E +   R+++Q L+ER E  + + ++D +  + E    +  +   L H 
Sbjct: 1606 -RQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD 1664

Query: 360  QDLAKMIREYEQVIIED------RIEKERSKKKVKQDL 391
            +D  +  RE EQ++ E       R E++R  ++ +Q L
Sbjct: 1665 RD--RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 59/275 (21%), Positives = 112/275 (40%), Gaps = 50/275 (18%)

Query: 197  QALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQ 256
            Q   +ERE ++       R ++ RK     ++QL+   +E Q   Q ++      + QL+
Sbjct: 1651 QLRRQEREQQL-------RHDRDRK--FREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701

Query: 257  EMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVE----------------EIEKLRM 300
              +     E ++++   +L+  + ++K    E+L  E                E E+LR 
Sbjct: 1702 RQER----ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757

Query: 301  KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQ 360
            + EE+     E +   R+E+Q  +ER E  +   + D + ++ E    +  +   L   Q
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE-QLRQEREEQQLRPQQ 1816

Query: 361  DLAKMIREYEQVIIED-----RIEKERSKKKVKQDLLELKSVIKLQAWW----------- 404
               K   E EQ+ +E+     R E++R  +  +Q   + KS  + Q  W           
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876

Query: 405  ----RGTMIRREIGGFKMPKDKVDSKDSKGKGKGK 435
                R   IRR+    +  +   + K  +GKG G+
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 49/243 (20%), Positives = 105/243 (43%), Gaps = 23/243 (9%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKA 260
           K +E +      +  E++ R++    ++QL+  ++E + E + + + +   +++ ++   
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579

Query: 261 KSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQ 320
           K   E R  +   E +    Q+       L  EE+E+L  +   E R   E     R++Q
Sbjct: 580 KREEERRQQRLKREQEERLEQR-------LKREEVERLEQEERREQRLKREEPEEERRQQ 632

Query: 321 QKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEK 380
               E  E   E+  +    +Q E    +  +  +   L+   K  RE+E    E+R E+
Sbjct: 633 LLKSEEQE---ERRQQQLRREQQERREQRLKREEEEERLEQRLK--REHE----EERREQ 683

Query: 381 ERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSKGKGKGKDKRRG 440
           E ++++ +Q    +KS I    W     +  E       + KV S+  K +G+ + + + 
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQW----QLESEADA---RQSKVYSRPRKQEGQRRRQEQE 736

Query: 441 KKK 443
           +K+
Sbjct: 737 EKR 739



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 48/223 (21%), Positives = 100/223 (44%), Gaps = 39/223 (17%)

Query: 199 LSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQL--- 255
           L +E E + H       E++ RKQ +   ++    ++  + E + + E     + QL   
Sbjct: 458 LKREEETERH-------EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510

Query: 256 ------QEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTH 309
                 Q +K +   E    +  +E Q+ + Q++  R E+LL  E EK   + E+E R  
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEE--RREQLLKREEEK---RLEQERR-- 563

Query: 310 TEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREY 369
              E  L++EQ++  ++L        ++ E +Q  L   +  +       +++ ++ +E 
Sbjct: 564 ---EQRLKREQEERRDQL------LKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614

Query: 370 EQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRRE 412
            +   E R+++E  +++ +Q LL+ +     Q   R   +RRE
Sbjct: 615 RR---EQRLKREEPEEERRQQLLKSEE----QEERRQQQLRRE 650



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 31/198 (15%), Positives = 96/198 (48%), Gaps = 7/198 (3%)

Query: 197  QALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIAN---LKD 253
            Q   +ER+ K    +   R ++  ++ +  ++QL   + + Q   +   ++  +   L++
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630

Query: 254  QLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIE 313
            + ++   +   + ++++   +L+  + +++     +    E E+L  + EE+     E +
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690

Query: 314  MFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIRE--YEQ 371
               R+E+Q+L  R E   +   ++ ++++ EL   K  +   L    +  ++ R+  Y +
Sbjct: 1691 RKFREEEQQL-RRQERERKFLQEEQQLRRQELER-KFREEEQLRQETEQEQLRRQERYRK 1748

Query: 372  VIIEDRIEKERSKKKVKQ 389
            ++ E+++  ER ++++++
Sbjct: 1749 ILEEEQLRPEREEQQLRR 1766



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 40/205 (19%), Positives = 100/205 (48%), Gaps = 19/205 (9%)

Query: 197 QALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKK-EWQFEVQSQNEYIANLKDQ- 254
           Q   +ER++++ F +   +E + R+ ++  +++ +  ++ + Q E+Q + E +  L+ Q 
Sbjct: 227 QQQRRERQDRV-FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285

Query: 255 LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLV--------EEIEKLRMKTEEEA 306
           L+  + +   + + ++   +L+  Q +++  + EE           EE  + +++ E+E 
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345

Query: 307 RTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK-- 364
           R     E  LR+EQ+  EER E  + +  ++   +Q      +  +   L   Q L +  
Sbjct: 346 RR----EQQLRREQE--EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399

Query: 365 MIREYEQVIIEDRIEKERSKKKVKQ 389
            +R  +Q+  E ++ +E+  ++ +Q
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQ 424



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 53/254 (20%), Positives = 117/254 (46%), Gaps = 35/254 (13%)

Query: 142 EFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSK 201
           E  K+Q+   ++P RQ  +  E  +  +++RQ   ++  +  +E Q         Q   K
Sbjct: 256 EEEKLQE---EEPQRQRELQEEEEQLRKLERQ---ELRRERQEEEQQQQRLRREQQLRRK 309

Query: 202 ERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAK 261
           + E +    +    +++ R+Q    ++Q +  ++E + E Q + E     ++Q  +++ +
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ--QLRRE 367

Query: 262 SNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLR---MKTEEEARTHTEI--EMFL 316
              E R  +   E Q+ + Q+   R E+ L  E +  R   ++ E++ R   ++  E  L
Sbjct: 368 QEEERREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425

Query: 317 RKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIED 376
           R+EQ+  EER E   E+  ++  +K+ +               ++    ++  E+    +
Sbjct: 426 RREQE--EERHEQKHEQERREQRLKREQ---------------EERRDWLKREEET---E 465

Query: 377 RIEKERSKKKVKQD 390
           R E+ER K+++K+D
Sbjct: 466 RHEQERRKQQLKRD 479



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 50/219 (22%), Positives = 94/219 (42%), Gaps = 24/219 (10%)

Query: 215 REEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLE--NRYMKTN 272
           REE+ R +   LQ    +  +E+  E Q +   +  L+ + +E K +   E  +R  +  
Sbjct: 183 REER-RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241

Query: 273 TELQIAQTQKKCNRTEEL-----------LVEEIEKLRMKTEEEARTHTEIE----MFLR 317
            E +  + +    + EE            L EE E+LR    +E R   + E      LR
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301

Query: 318 KEQQ----KLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI 373
           +EQQ    + EER E   E+ ++    +Q E    +  +       +   ++ RE E+  
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ--QLRREQEEER 359

Query: 374 IEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRRE 412
            E ++ +E+ +++ +Q L   + + + Q   R   +RRE
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 45/228 (19%), Positives = 93/228 (40%), Gaps = 34/228 (14%)

Query: 185  ELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQ 244
            +L+D  +   L   L +++E          RE++ R+     Q++  +  +E Q E + Q
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQERD--------REQERRRW----QQRDRHFPEEEQLEREEQ 1304

Query: 245  NEYIA-NLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTE 303
             E    + K Q ++   +   E +  +  T+ +  + ++     EE  +   E+ R   E
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364

Query: 304  EEARTHTEIEMFLRKEQQ--KLEERLEFWME-------------KYDKDTEMKQNELNA- 347
            EE R   +   FL +EQ+  + E   +F  E             + D+D + ++ E    
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS 1424

Query: 348  -----LKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQD 390
                  K  +       Q+  +   E EQ + ++R  K R ++++ Q+
Sbjct: 1425 RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 78/344 (22%), Positives = 148/344 (43%), Gaps = 37/344 (10%)

Query: 67   VLEDTTDQLSILNYIMPVQY----EGRQSI--------CVKSREMNLEGTNLDKLPMAST 114
            +++   ++L   N  + VQ     EG++++        C K++   LE     +    S 
Sbjct: 1080 LIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSH 1139

Query: 115  ITKIPSPLITEEG------PNLPEIRHRGRFAVEFNK---MQDLVFKKPTRQTIMTTETL 165
              K+   ++ +E        NL E +   + +V+  K   +++L  K+   Q     + +
Sbjct: 1140 SAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDM 1199

Query: 166  KKI-QIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFY-DIIAREEKGRKQI 223
            K + Q+  +       +T K  ++ +  ++  Q L  + + K   Y D+  +    +KQI
Sbjct: 1200 KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQI 1259

Query: 224  ISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSN----LENRYMKTNTELQIAQ 279
              +QK++  ++ E +      NE         QE+  K      L+ +      E  I Q
Sbjct: 1260 KQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQ 1319

Query: 280  TQKKCNRTEELLVEE--IEKLRMKTEEEARTHTEIEMFLR---KEQQKLEERLEFWMEKY 334
             ++ C   ++L V+E  IE +RM  EE+ +T  E +  L    +E ++L   LE W EK 
Sbjct: 1320 YERAC---KDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKC 1376

Query: 335  DKDTEMKQNELNALKATKASD-LAHLQDLAKMIREYEQVIIEDR 377
            + D E K N+ +  +    +D L  L +L   ++E EQ    DR
Sbjct: 1377 N-DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADR 1419



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 44/210 (20%), Positives = 92/210 (43%), Gaps = 17/210 (8%)

Query: 166  KKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIIS 225
            K + +  +   D+     ++ Q     + +L+A  +E E       +    EK +++   
Sbjct: 1325 KDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVER------LATELEKWKEKCND 1378

Query: 226  LQ---KQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQK 282
            L+    Q  N + E   +V  +   + NL+D+LQE + K N + +  K   E  +  TQ 
Sbjct: 1379 LETKNNQRSNKEHENNTDVLGK---LTNLQDELQESEQKYNADRK--KWLEEKMMLITQA 1433

Query: 283  KCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQ 342
            K    E +  +E++K     E   +   E+E+   +  +K +  L+ W E+ D+     +
Sbjct: 1434 K--EAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEK-DSDLQKWREERDQLVAALE 1490

Query: 343  NELNALKATKASDLAHLQDLAKMIREYEQV 372
             +L AL ++       ++ L ++I E  ++
Sbjct: 1491 IQLKALISSNVQKDNEIEQLKRIISETSKI 1520



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 58/302 (19%), Positives = 124/302 (41%), Gaps = 24/302 (7%)

Query: 96   SREMNLEGTNLDKLPMASTITKIPSPLITEEGPNLPEIRHRGRFAVEFNKMQDLV--FKK 153
            S E NL  T LD L     ++K       +E PN     H    A+ + + +++V    K
Sbjct: 976  SEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE-PNRENSFHSSIEAI-WEECKEIVKASSK 1033

Query: 154  PTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDS------ATYNSLLQALSKERENKM 207
             + Q     + ++K+Q + + + D   + +KE +            +L+Q L +E + K 
Sbjct: 1034 KSHQIEELEQQIEKLQAEVKGYKDE-NNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKN 1092

Query: 208  HFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENR 267
               D+  +     K+ +S   Q +   K    E+++       L+ Q  E    + LE  
Sbjct: 1093 VTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETI------LETQKVECSHSAKLEQD 1146

Query: 268  YMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERL 327
             ++   E  I + ++     +E L + ++  +    +E +   EI       Q      +
Sbjct: 1147 ILEK--ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD-----M 1199

Query: 328  EFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKV 387
            +  ++  +++ E  + E   LK   ++  A  Q+L   ++  E+   + + +   +KK++
Sbjct: 1200 KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQI 1259

Query: 388  KQ 389
            KQ
Sbjct: 1260 KQ 1261


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 52/231 (22%), Positives = 107/231 (46%), Gaps = 29/231 (12%)

Query: 183  IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQ 242
            IK L  SA     +  + +E +      D +A+ E  RK++      L+  K + Q +VQ
Sbjct: 839  IKPLLKSAETEKEMATMKEEFQKTK---DELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 895

Query: 243  SQNEYIANLKDQLQEM-KAKSNLENRYMKT------NTELQIAQTQKK------CNRTE- 288
            S+ + +A+ +++ +++ K K  LE +  +         E+    T KK      C+  + 
Sbjct: 896  SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955

Query: 289  -----ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDK---DTEM 340
                 EL + ++EK +  TE + +  TE    L +   KL +  +   E + +   D + 
Sbjct: 956  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015

Query: 341  KQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDL 391
            +++++N L   K      + DL   + + +++    R++ ER+K+K++ DL
Sbjct: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKL----RMDLERAKRKLEGDL 1062



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 62/262 (23%), Positives = 122/262 (46%), Gaps = 20/262 (7%)

Query: 141  VEFNKMQDLVFKKPTRQTIMTT-ETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQAL 199
            VE NK ++  F+K  R     T +    +   R+  +D +A+  +++ +      + Q L
Sbjct: 1164 VELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDN---LQRVKQKL 1220

Query: 200  SKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
             KE+ E KM   D+ +  E   K   +L+K   +++ +   E++++ E    L + L   
Sbjct: 1221 EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS-ELKTKEEEQQRLINDLTAQ 1279

Query: 259  KAKSNLE-NRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLR 317
            +A+   E   Y +   E     +Q   +R+++   ++IE+L+ + EEE    T+ +  L 
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQ--LSRSKQASTQQIEELKHQLEEE----TKAKNALA 1333

Query: 318  KEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDR 377
               Q      +   E+Y+++ E K     AL  +KA+      ++A+   +YE   I+  
Sbjct: 1334 HALQSSRHDCDLLREQYEEEQEGKAELQRAL--SKAN-----SEVAQWRTKYETDAIQRT 1386

Query: 378  IEKERSKKKVKQDLLELKSVIK 399
             E E +KKK+ Q L E +  ++
Sbjct: 1387 EELEEAKKKLAQRLQEAEEHVE 1408



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 57/262 (21%), Positives = 110/262 (41%), Gaps = 31/262 (11%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYD 211
            K  T +     ET+ K+  +++   +    T+ +LQ      ++L     + E ++   D
Sbjct: 979  KNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD--D 1036

Query: 212  IIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLE--NRYM 269
            +    E+ +K  + L++    ++ + +   +S  + + N K QL E   K   E  N   
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD-MENDKQQLDEKLEKKEFEISNLIS 1095

Query: 270  KTNTELQIA-QTQKKCNRTE---ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEE 325
            K   E  +  Q QKK    +   E L EEIE  R    +  +  +++   L +  ++LEE
Sbjct: 1096 KIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1155

Query: 326  ---------------RLEFWMEKYDKDTEMKQNE--LNALKATKASDLAHLQDLAKMIRE 368
                             EF   + D +    Q+E  + AL+   A  +A L +    ++ 
Sbjct: 1156 AGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQR 1215

Query: 369  YEQVIIEDRIEKERSKKKVKQD 390
             +Q     ++EKE+S+ K++ D
Sbjct: 1216 VKQ-----KLEKEKSELKMETD 1232



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 68/286 (23%), Positives = 125/286 (43%), Gaps = 53/286 (18%)

Query: 142  EFNKMQDLVFKKPTRQTIMTTE--TLKK----IQIDRQFFSDVIADTIKELQDSATYNSL 195
            EF K +D + K   ++  +  +  TL K    +Q+  Q  +D +AD  +  +        
Sbjct: 858  EFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQ 917

Query: 196  LQALSKE-----RENKMHFYDIIAREEKG-------RKQIISLQKQLINVKKE---WQFE 240
            L+A  KE      E +    ++ A++ K        +K I  L+  L  V+KE    + +
Sbjct: 918  LEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 977

Query: 241  VQSQNEYIANLKDQLQEM-KAKSNLENRYMKTNTELQIAQTQ----KKCNRTEELLVEEI 295
            V++  E +A L + + ++ K K  L+  + +T  +LQ  + +     K     E  V+++
Sbjct: 978  VKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDL 1037

Query: 296  E-------KLRM-------KTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMK 341
            E       KLRM       K E + +   E  M +  ++Q+L+E+L           E K
Sbjct: 1038 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL-----------EKK 1086

Query: 342  QNELNALKATKASDLAHLQDLAKMIREYEQVIIE--DRIEKERSKK 385
            + E++ L +    + A    L K I+E +  I E  + IE ER+ +
Sbjct: 1087 EFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASR 1132



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 78/371 (21%), Positives = 145/371 (39%), Gaps = 59/371 (15%)

Query: 64   ISAVLEDTTDQLSILNYIMPVQYE---GRQSICVKSREMNLEGTNLDKLPMASTITKIPS 120
            +S  LE+ +++L         Q E    R++   K R  +LE   L    M + + K  +
Sbjct: 1142 LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRR-DLEEATLQHEAMVAALRKKHA 1200

Query: 121  PLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIA 180
              + E G  +  ++ R +  +E  K +    K  T       E + K + + +     + 
Sbjct: 1201 DSMAELGEQIDNLQ-RVKQKLEKEKSE---LKMETDDLSSNAEAISKAKGNLEKMCRSLE 1256

Query: 181  DTIKELQ-----------DSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQ 229
            D + EL+           D     + LQ  + E   ++   D +  +    KQ  +  +Q
Sbjct: 1257 DQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAST--QQ 1314

Query: 230  LINVKKEWQFEVQSQNEYIANL--------------------KDQLQEMKAKSNLENRYM 269
            +  +K + + E +++N     L                    K +LQ   +K+N E    
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374

Query: 270  KTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEF 329
            +T  E    Q      RTEEL  EE +K   +  +EA  H E         +K ++RL+ 
Sbjct: 1375 RTKYETDAIQ------RTEEL--EEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQN 1426

Query: 330  WMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKK--- 386
             +E    D E       AL   +       ++  K++ E++Q   E + E E S+K+   
Sbjct: 1427 EVEDLMLDVERSNAACAALDKKQ-------RNFDKVLSEWKQKYEETQAELEASQKESRS 1479

Query: 387  VKQDLLELKSV 397
            +  +L ++K+V
Sbjct: 1480 LSTELFKVKNV 1490



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 47/224 (20%), Positives = 99/224 (44%), Gaps = 22/224 (9%)

Query: 196  LQALSKEREN-KMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
            L+ L +E +N +    D+  +  +G KQI  L+K    V++E + E+Q+  E      + 
Sbjct: 1498 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQE-KCEIQAALEEAEASLEH 1556

Query: 255  LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEM 314
             +    +  LE   +K+  + +IA+  ++ ++ +      +E ++   + E R+  +   
Sbjct: 1557 EEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALR 1616

Query: 315  FLRKEQQKLEERLEFWMEKYDK-DTEMKQNELNALKATKASDLAHLQDLAKMIREYEQ-- 371
              +K +  L E +E  +   ++   E  +N  N     K + L HL D  +   + ++  
Sbjct: 1617 VKKKMEGDLNE-MEIQLNHANRLAAESLRNYRNTQGILKETQL-HLDDALRGQEDLKEQL 1674

Query: 372  VIIEDRI---------------EKERSKKKVKQDLLELKSVIKL 400
             I+E R                + ERS+K  +Q+LL+    ++L
Sbjct: 1675 AIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQL 1718



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 20/212 (9%)

Query: 194  SLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKD 253
            +LLQA  +E       +  + + E+ RK     +++L++  +  Q  + +QN  + N K 
Sbjct: 1682 NLLQAEIEE------LWATLEQTERSRK---IAEQELLDASERVQL-LHTQNTSLINTKK 1731

Query: 254  QLQEMKAKSNLENRYMKTNTELQIAQTQ-KKCNRTEELLVEEIEKLRMKTEEEARTHTEI 312
            +L+     S L++   +   E + A+ + KK      ++ EE++K +  +    R    +
Sbjct: 1732 KLEN--DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1789

Query: 313  EMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQV 372
            E  ++  Q +L+E  +  ++   K  +  +  +  L+    ++     +  K +R++E+ 
Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849

Query: 373  IIEDRIEKERSKKKV--KQDLLELKSVIKLQA 402
            + E   + E  +K V   QDL++     KLQA
Sbjct: 1850 VKELTYQTEEDRKNVLRLQDLVD-----KLQA 1876


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 66/295 (22%), Positives = 134/295 (45%), Gaps = 55/295 (18%)

Query: 157  QTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQALSK---ERENKMHFYDI- 212
            Q     E L  I+ +    +  + D   +  D  ++ SL++ L K   E++ K+   +  
Sbjct: 757  QVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEEL 816

Query: 213  -------IAREEKG----RKQIISLQKQLINVK--KEWQFEVQSQNEYIANL----KDQL 255
                   +A +EK     +++I +L++++ NV+  K  Q  + S+ + + NL    ++Q+
Sbjct: 817  LEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQM 876

Query: 256  QEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMF 315
              MKA    + + +  NT   +   Q++ N + +  V+E+ +  +K    A    E+E+ 
Sbjct: 877  NTMKAVLEEKEKDL-ANTGKWLQDLQEE-NESLKAHVQEVAQHNLKEASSASQFEELEIV 934

Query: 316  LRKEQQKLEERLEFWMEKYDKDTEMK-------QNELNALKA----------TKASDLAH 358
            L++++ +L +RLE  +++ + D   K       Q+E    K+           +AS    
Sbjct: 935  LKEKENEL-KRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993

Query: 359  LQDLAKMIREYEQVI---------IEDRIEKERSKKKVKQDL-----LELKSVIK 399
             ++L K+I E E+ I         ++D +E +R K   +Q       LE K V+K
Sbjct: 994  HEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLK 1048



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 63/279 (22%), Positives = 122/279 (43%), Gaps = 38/279 (13%)

Query: 177 DVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKE 236
           D +    +EL+D    N LL+A  ++ +   +     A E +  +Q + ++   I + +E
Sbjct: 628 DRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEE 687

Query: 237 W-QFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEI 295
             Q E+ ++ E    L DQ + +K++       +       + +  +KC      + E+ 
Sbjct: 688 QLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKC------IQEKD 741

Query: 296 EKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASD 355
           EKL  KT EE      I++  ++E+          + K  +D + KQN+       + S 
Sbjct: 742 EKL--KTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQND-------QVSF 792

Query: 356 LAHLQDLAKMIREYE------QVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMI 409
            + +++L K+I E +      + ++E  + K  +K+K  QD   LK  IK         +
Sbjct: 793 ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQD---LKQEIK--------AL 841

Query: 410 RREIGGFKMPKDKVDSKDSKGKG-----KGKDKRRGKKK 443
           + EIG  ++ K +  S  SK +      KGK+++    K
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMK 880



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 38/187 (20%), Positives = 87/187 (46%), Gaps = 15/187 (8%)

Query: 217 EKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQ 276
           E+   Q++  +++ +N ++  Q +VQ   E    LK Q+Q+  ++   +        EL 
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELH 606

Query: 277 --IAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKL------EERLE 328
             IA+  K+  +TE+ L  E ++L  K EEE +    +   L+ E QKL      +    
Sbjct: 607 KVIAEKDKQIKQTEDSLASERDRLTSK-EEELKDIQNMNFLLKAEVQKLQALANEQAAAA 665

Query: 329 FWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI------IEDRIEKER 382
             +EK  +   +K +++  L+     ++++  +  K++ +  + +      ++  + ++ 
Sbjct: 666 HELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQP 725

Query: 383 SKKKVKQ 389
           +K  V+Q
Sbjct: 726 NKDVVEQ 732



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 52/241 (21%), Positives = 97/241 (40%), Gaps = 48/241 (19%)

Query: 188  DSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISL--QKQLINVKKEWQFEVQSQN 245
            D ++   LLQ +  + ENK+    I   +++  +Q  S    ++L+ V  E + E+    
Sbjct: 955  DLSSKTQLLQDV--QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLW 1012

Query: 246  EYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKC--------------------N 285
              + +LKD ++  + K+N E +      EL+  +  KK                      
Sbjct: 1013 NELDSLKDAVEHQRKKNN-ERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEK 1071

Query: 286  RTEELLV-----EEIEKLRMKTEEEARTHT--------------EIEMFLRKEQQKLEER 326
            + +E +      EE++ L  K +E    HT              E E  L+K Q+ +E+ 
Sbjct: 1072 KAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQE 1131

Query: 327  LEFWMEKYD---KDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIE-DRIEKER 382
               W  K D   K  +  Q+   + +       +  +D+  + RE E + +E ++ E ER
Sbjct: 1132 ENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMER 1191

Query: 383  S 383
            S
Sbjct: 1192 S 1192


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 62/288 (21%), Positives = 120/288 (41%), Gaps = 39/288 (13%)

Query: 132 EIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVI--ADTIKELQDS 189
           EI   G  A E++K +  + K     T       K I  +R+        AD  + L+D 
Sbjct: 157 EISRSGELAQEYDKRKKEMVKAE-EDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDE 215

Query: 190 ATYNSLLQALSKERENKMHFYDI---IARE----EKGRKQIISLQKQLINVKKEWQFEVQ 242
                +   L K   N++    +   +A +    EK +K++  ++ +L   KKE    ++
Sbjct: 216 VVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMR 275

Query: 243 SQNEYIANLKDQLQEM--------KAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEE 294
            Q +    +K++  E+        KAK N  ++  K     +  Q  +K  +  +  ++E
Sbjct: 276 EQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDE 335

Query: 295 IEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKAS 354
           +EK  +  E              K +Q+ EER+E   +   +D  +++N++      K  
Sbjct: 336 LEKEMLSVE--------------KARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEE 381

Query: 355 DLAHLQDLAKMIREY--EQVIIEDRIEKERSKK-----KVKQDLLELK 395
                  LA+ + ++  +Q   +DR++ E  KK     K+KQ L E++
Sbjct: 382 ASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIE 429



 Score = 37.0 bits (84), Expect = 0.036
 Identities = 41/199 (20%), Positives = 90/199 (45%), Gaps = 27/199 (13%)

Query: 201 KERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKA 260
           K  + +   ++ I+R  +  ++    +K+++  +++ QF    +    A  K+  QE + 
Sbjct: 146 KNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEE 205

Query: 261 KSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQ 320
                +RY +   E+  AQ Q +  +     VE IEKL    +E A  + EIE    K++
Sbjct: 206 A----DRYQRLKDEVVRAQVQLQLFKLYHNEVE-IEKLN---KELASKNKEIE----KDK 253

Query: 321 QKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEK 380
           ++        M+K + + + K+ EL  +       +   Q + K I+E +  + + R + 
Sbjct: 254 KR--------MDKVEDELKEKKKELGKM-------MREQQQIEKEIKEKDSELNQKRPQY 298

Query: 381 ERSKKKVKQDLLELKSVIK 399
            ++K+     + +L++  K
Sbjct: 299 IKAKENTSHKIKKLEAAKK 317



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 56/250 (22%), Positives = 103/250 (41%), Gaps = 44/250 (17%)

Query: 200 SKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFE---VQSQNEYIANLKDQLQ 256
           S+ERE K    D+  +  +   ++     + I V+   +FE   V+ QNE IA  + + +
Sbjct: 757 SREREMK----DLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNE-IAKKRLEFE 811

Query: 257 EMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFL 316
             K +  ++  + K     Q+ + Q K +  E+ + ++  ++    +EE R    I+  +
Sbjct: 812 NQKTRLGIQLDFEKN----QLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETM 867

Query: 317 RKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIED 376
            + Q    + L    E  DK+ EM++       A K  ++ HLQ         E   IE 
Sbjct: 868 AQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANK--EMTHLQK--------EVTAIET 917

Query: 377 RIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPKDK---VDSKDSKGKGK 433
           ++E++RS      D   L    K+Q               K+P  K    D    +G  +
Sbjct: 918 KLEQKRS------DRHNLLQACKMQ-------------DIKLPLSKGTMDDISQEEGSSQ 958

Query: 434 GKDKRRGKKK 443
           G+D   G ++
Sbjct: 959 GEDSVSGSQR 968



 Score = 32.3 bits (72), Expect = 0.89
 Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 7/122 (5%)

Query: 194 SLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKD 253
           +L Q L K   ++    D +  EE+ + +  +  KQ +   +E Q  ++   EYI   K 
Sbjct: 388 TLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQ 447

Query: 254 QLQEMKAKSNLENRYMKTNTELQIAQTQ-KKCNRTEELLVEEIEKLRMKTEEEARTHTEI 312
            L+E K    LE    +   E+++A+ +  + N+    ++E++   R+  +E +R   + 
Sbjct: 448 SLEEQK---KLEG---ELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKA 501

Query: 313 EM 314
           E+
Sbjct: 502 EI 503


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 54/242 (22%), Positives = 113/242 (46%), Gaps = 30/242 (12%)

Query: 183  IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQ 242
            IK L  SA     +  + +E +      D +A+ E  RK++      L+  K + Q +VQ
Sbjct: 842  IKPLLKSAETEKEMATMKEEFQK---IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 898

Query: 243  SQNEYIANLKDQLQEM-KAKSNLENRYMKT------NTELQIAQTQKK------CNRTE- 288
            ++ E +A+ +++  ++ K K  LE +  +         E+    T KK      C+  + 
Sbjct: 899  AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958

Query: 289  -----ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDK---DTEM 340
                 EL + ++EK +  TE + +  TE    L +   KL +  +   E + +   D + 
Sbjct: 959  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQA 1018

Query: 341  KQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIK 399
            +++++N L   K      + DL   + + +++    R++ ER+K+K++ DL L  +S++ 
Sbjct: 1019 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL----RMDLERAKRKLEGDLKLAQESIMD 1074

Query: 400  LQ 401
            ++
Sbjct: 1075 IE 1076



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/260 (23%), Positives = 113/260 (43%), Gaps = 32/260 (12%)

Query: 141  VEFNKMQDLVFKKPTR-------QTIMTTETLKKIQIDRQFFSDVIADTIKELQDSA-TY 192
            +E NK ++  F+K  R       Q   T  TL+K            AD++ EL +     
Sbjct: 1167 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH----------ADSVAELGEQIDNL 1216

Query: 193  NSLLQALSKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL 251
              + Q L KE+ E KM   D+ +  E   K   +L+K    ++ +   E++S+ E    L
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS-ELKSKEEEQQRL 1275

Query: 252  KDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTE 311
             + L   + +   E+       + + A   +  +R ++   ++IE+L+ + EEE +    
Sbjct: 1276 INDLTAQRGRLQTESGEFSRQLDEKEALVSQ-LSRGKQAFTQQIEELKRQLEEEIKAKNA 1334

Query: 312  IEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQ 371
            +   L    Q      +   E+Y+++ E K     AL  +KA+      ++A+   +YE 
Sbjct: 1335 LAHAL----QSSRHDCDLLREQYEEEQESKAELQRAL--SKAN-----TEVAQWRTKYET 1383

Query: 372  VIIEDRIEKERSKKKVKQDL 391
              I+   E E +KKK+ Q L
Sbjct: 1384 DAIQRTEELEEAKKKLAQRL 1403



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/262 (22%), Positives = 109/262 (41%), Gaps = 31/262 (11%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQ-DSATYNSLLQALSKERENKMHFY 210
            K  T +     ET+ K+  +++   +    T+ +LQ +    N+L +A  K  +      
Sbjct: 982  KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1041

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK 270
              + +E+K R  +   +++L    K  Q  +      I N K QL E   K   E   ++
Sbjct: 1042 GSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD----IENEKQQLDEKLKKKEFEISNLQ 1097

Query: 271  TNTELQIA---QTQKKCNRTE---ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLE 324
            +  E + A   Q QKK    +   E L EEIE  R    +  +  +++   L +  ++LE
Sbjct: 1098 SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157

Query: 325  E---------------RLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREY 369
            E                 EF   + D +    Q+E  A    K     H   +A++  + 
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK----KHADSVAELGEQI 1213

Query: 370  EQV-IIEDRIEKERSKKKVKQD 390
            + +  ++ ++EKE+S+ K++ D
Sbjct: 1214 DNLQRVKQKLEKEKSEMKMEID 1235



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/253 (22%), Positives = 114/253 (45%), Gaps = 40/253 (15%)

Query: 167  KIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISL 226
            KIQ++ +     I +  +  +D    N+ L A  ++ E++           + +K I  L
Sbjct: 918  KIQLEAK-----IKEVTERAEDEEEINAELTAKKRKLEDEC---------SELKKDIDDL 963

Query: 227  QKQLINVKKE---WQFEVQSQNEYIANLKDQLQEM-KAKSNLENRYMKTNTELQIAQ--- 279
            +  L  V+KE    + +V++  E +A L + + ++ K K  L+  + +T  +LQ  +   
Sbjct: 964  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023

Query: 280  -TQKKCNRTEELLVEEIE-------KLRM-------KTEEEARTHTEIEMFLRKEQQKLE 324
             T  K     E  V+++E       KLRM       K E + +   E  M +  E+Q+L+
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083

Query: 325  ERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSK 384
            E+L    +K + +    Q+++   +A        +++L   I E E+ I  +R  + +++
Sbjct: 1084 EKL----KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139

Query: 385  KKVKQDLLELKSV 397
            K+      EL+ +
Sbjct: 1140 KQRSDLSRELEEI 1152



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 80/367 (21%), Positives = 146/367 (39%), Gaps = 53/367 (14%)

Query: 64   ISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREM--NLEGTNLDKLPMASTITKIPSP 121
            +S  LE+ +++L         Q E  +    + ++M  +LE   L     A+T+ K  + 
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204

Query: 122  LITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIAD 181
             + E G  +  ++ R +  +E  K +    K          ET+ K + + +     + D
Sbjct: 1205 SVAELGEQIDNLQ-RVKQKLEKEKSE---MKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260

Query: 182  TIKELQ-----------DSATYNSLLQALSKERENKMHFYD-IIAREEKGRK----QIIS 225
             + EL+           D       LQ  S E   ++   + ++++  +G++    QI  
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320

Query: 226  LQKQL---INVKKEWQFEVQS----------QNEYIANLKDQLQEMKAKSNLENRYMKTN 272
            L++QL   I  K      +QS          Q E     K +LQ   +K+N E    +T 
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380

Query: 273  TELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWME 332
             E    Q      RTEEL  EE +K   +  + A  H E         +K ++RL+  +E
Sbjct: 1381 YETDAIQ------RTEEL--EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE 1432

Query: 333  KYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ--- 389
                D E       AL   +       ++  K++ E++Q   E   E E S+K+ +    
Sbjct: 1433 DLMLDVERTNAACAALDKKQ-------RNFDKILAEWKQKCEETHAELEASQKEARSLGT 1485

Query: 390  DLLELKS 396
            +L ++K+
Sbjct: 1486 ELFKIKN 1492



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 47/205 (22%), Positives = 92/205 (44%), Gaps = 31/205 (15%)

Query: 202  ERENKMHFYDIIAREEKGRKQIISLQK-QLINVKKEWQFEV-QSQNEYIANLKDQLQEMK 259
            ER  K+   +++   E  R Q++  Q   LIN KK+ + ++ Q Q E    ++D LQE +
Sbjct: 1702 ERSRKIAEQELLDASE--RVQLLHTQNTSLINTKKKLETDISQMQGE----MEDILQEAR 1755

Query: 260  AKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKE 319
               N E +  K  T+               ++ EE++K +  +    R    +E  ++  
Sbjct: 1756 ---NAEEKAKKAITDAA-------------MMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799

Query: 320  QQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIE 379
            Q +L+E  +  ++   K  +  +  +  L+    S+     +  K +R++E+ + E   +
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859

Query: 380  KERSKKKV--KQDLLELKSVIKLQA 402
             E  +K +   QDL++     KLQA
Sbjct: 1860 TEEDRKNILRLQDLVD-----KLQA 1879



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 42/222 (18%), Positives = 98/222 (44%), Gaps = 18/222 (8%)

Query: 196  LQALSKEREN-KMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
            L+ L +E +N +    D+  +  +G K+I  L+K    V++E + E+Q+  E      + 
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE-KCELQAALEEAEASLEH 1559

Query: 255  LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHT---- 310
             +    +  LE   +K+  + +IA+  ++ ++ +   +  +E ++   + E R+      
Sbjct: 1560 EEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR 1619

Query: 311  ----------EIEMFLRKEQQKLEERLEFWMEKYD--KDTEMKQNELNALKATKASDLAH 358
                      E+E+ L    +   E L  +       KDT++  ++    +      LA 
Sbjct: 1620 LKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAM 1679

Query: 359  LQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKL 400
            ++  A +++   + +     + ERS+K  +Q+LL+    ++L
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL 1721


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 54/242 (22%), Positives = 113/242 (46%), Gaps = 30/242 (12%)

Query: 183  IKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQ 242
            IK L  SA     +  + +E +      D +A+ E  RK++      L+  K + Q +VQ
Sbjct: 842  IKPLLKSAETEKEMATMKEEFQK---IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 898

Query: 243  SQNEYIANLKDQLQEM-KAKSNLENRYMKT------NTELQIAQTQKK------CNRTE- 288
            ++ E +A+ +++  ++ K K  LE +  +         E+    T KK      C+  + 
Sbjct: 899  AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958

Query: 289  -----ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDK---DTEM 340
                 EL + ++EK +  TE + +  TE    L +   KL +  +   E + +   D + 
Sbjct: 959  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQA 1018

Query: 341  KQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIK 399
            +++++N L   K      + DL   + + +++    R++ ER+K+K++ DL L  +S++ 
Sbjct: 1019 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL----RMDLERAKRKLEGDLKLAQESIMD 1074

Query: 400  LQ 401
            ++
Sbjct: 1075 IE 1076



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/260 (23%), Positives = 113/260 (43%), Gaps = 32/260 (12%)

Query: 141  VEFNKMQDLVFKKPTR-------QTIMTTETLKKIQIDRQFFSDVIADTIKELQDSA-TY 192
            +E NK ++  F+K  R       Q   T  TL+K            AD++ EL +     
Sbjct: 1167 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH----------ADSVAELGEQIDNL 1216

Query: 193  NSLLQALSKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL 251
              + Q L KE+ E KM   D+ +  E   K   +L+K    ++ +   E++S+ E    L
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS-ELKSKEEEQQRL 1275

Query: 252  KDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTE 311
             + L   + +   E+       + + A   +  +R ++   ++IE+L+ + EEE +    
Sbjct: 1276 INDLTAQRGRLQTESGEFSRQLDEKEALVSQ-LSRGKQAFTQQIEELKRQLEEEIKAKNA 1334

Query: 312  IEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQ 371
            +   L    Q      +   E+Y+++ E K     AL  +KA+      ++A+   +YE 
Sbjct: 1335 LAHAL----QSSRHDCDLLREQYEEEQESKAELQRAL--SKAN-----TEVAQWRTKYET 1383

Query: 372  VIIEDRIEKERSKKKVKQDL 391
              I+   E E +KKK+ Q L
Sbjct: 1384 DAIQRTEELEEAKKKLAQRL 1403



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/262 (22%), Positives = 109/262 (41%), Gaps = 31/262 (11%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQ-DSATYNSLLQALSKERENKMHFY 210
            K  T +     ET+ K+  +++   +    T+ +LQ +    N+L +A  K  +      
Sbjct: 982  KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1041

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK 270
              + +E+K R  +   +++L    K  Q  +      I N K QL E   K   E   ++
Sbjct: 1042 GSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD----IENEKQQLDEKLKKKEFEISNLQ 1097

Query: 271  TNTELQIA---QTQKKCNRTE---ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLE 324
            +  E + A   Q QKK    +   E L EEIE  R    +  +  +++   L +  ++LE
Sbjct: 1098 SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157

Query: 325  E---------------RLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREY 369
            E                 EF   + D +    Q+E  A    K     H   +A++  + 
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK----KHADSVAELGEQI 1213

Query: 370  EQV-IIEDRIEKERSKKKVKQD 390
            + +  ++ ++EKE+S+ K++ D
Sbjct: 1214 DNLQRVKQKLEKEKSEMKMEID 1235



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/253 (22%), Positives = 114/253 (45%), Gaps = 40/253 (15%)

Query: 167  KIQIDRQFFSDVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISL 226
            KIQ++ +     I +  +  +D    N+ L A  ++ E++           + +K I  L
Sbjct: 918  KIQLEAK-----IKEVTERAEDEEEINAELTAKKRKLEDEC---------SELKKDIDDL 963

Query: 227  QKQLINVKKE---WQFEVQSQNEYIANLKDQLQEM-KAKSNLENRYMKTNTELQIAQ--- 279
            +  L  V+KE    + +V++  E +A L + + ++ K K  L+  + +T  +LQ  +   
Sbjct: 964  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023

Query: 280  -TQKKCNRTEELLVEEIE-------KLRM-------KTEEEARTHTEIEMFLRKEQQKLE 324
             T  K     E  V+++E       KLRM       K E + +   E  M +  E+Q+L+
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083

Query: 325  ERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSK 384
            E+L    +K + +    Q+++   +A        +++L   I E E+ I  +R  + +++
Sbjct: 1084 EKL----KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139

Query: 385  KKVKQDLLELKSV 397
            K+      EL+ +
Sbjct: 1140 KQRSDLSRELEEI 1152



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 80/367 (21%), Positives = 146/367 (39%), Gaps = 53/367 (14%)

Query: 64   ISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREM--NLEGTNLDKLPMASTITKIPSP 121
            +S  LE+ +++L         Q E  +    + ++M  +LE   L     A+T+ K  + 
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204

Query: 122  LITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIAD 181
             + E G  +  ++ R +  +E  K +    K          ET+ K + + +     + D
Sbjct: 1205 SVAELGEQIDNLQ-RVKQKLEKEKSE---MKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260

Query: 182  TIKELQ-----------DSATYNSLLQALSKERENKMHFYD-IIAREEKGRK----QIIS 225
             + EL+           D       LQ  S E   ++   + ++++  +G++    QI  
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320

Query: 226  LQKQL---INVKKEWQFEVQS----------QNEYIANLKDQLQEMKAKSNLENRYMKTN 272
            L++QL   I  K      +QS          Q E     K +LQ   +K+N E    +T 
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380

Query: 273  TELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWME 332
             E    Q      RTEEL  EE +K   +  + A  H E         +K ++RL+  +E
Sbjct: 1381 YETDAIQ------RTEEL--EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE 1432

Query: 333  KYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ--- 389
                D E       AL   +       ++  K++ E++Q   E   E E S+K+ +    
Sbjct: 1433 DLMLDVERTNAACAALDKKQ-------RNFDKILAEWKQKCEETHAELEASQKEARSLGT 1485

Query: 390  DLLELKS 396
            +L ++K+
Sbjct: 1486 ELFKIKN 1492



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 47/205 (22%), Positives = 92/205 (44%), Gaps = 31/205 (15%)

Query: 202  ERENKMHFYDIIAREEKGRKQIISLQK-QLINVKKEWQFEV-QSQNEYIANLKDQLQEMK 259
            ER  K+   +++   E  R Q++  Q   LIN KK+ + ++ Q Q E    ++D LQE +
Sbjct: 1702 ERSRKIAEQELLDASE--RVQLLHTQNTSLINTKKKLETDISQMQGE----MEDILQEAR 1755

Query: 260  AKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKE 319
               N E +  K  T+               ++ EE++K +  +    R    +E  ++  
Sbjct: 1756 ---NAEEKAKKAITDAA-------------MMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799

Query: 320  QQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIE 379
            Q +L+E  +  ++   K  +  +  +  L+    S+     +  K +R++E+ + E   +
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859

Query: 380  KERSKKKV--KQDLLELKSVIKLQA 402
             E  +K +   QDL++     KLQA
Sbjct: 1860 TEEDRKNILRLQDLVD-----KLQA 1879



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 42/222 (18%), Positives = 98/222 (44%), Gaps = 18/222 (8%)

Query: 196  LQALSKEREN-KMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQ 254
            L+ L +E +N +    D+  +  +G K+I  L+K    V++E + E+Q+  E      + 
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE-KCELQAALEEAEASLEH 1559

Query: 255  LQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHT---- 310
             +    +  LE   +K+  + +IA+  ++ ++ +   +  +E ++   + E R+      
Sbjct: 1560 EEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR 1619

Query: 311  ----------EIEMFLRKEQQKLEERLEFWMEKYD--KDTEMKQNELNALKATKASDLAH 358
                      E+E+ L    +   E L  +       KDT++  ++    +      LA 
Sbjct: 1620 LKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAM 1679

Query: 359  LQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKL 400
            ++  A +++   + +     + ERS+K  +Q+LL+    ++L
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL 1721


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 49/218 (22%), Positives = 108/218 (49%), Gaps = 35/218 (16%)

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM-KAKSNLE---- 265
            + + + E  RK++      L+  K + Q +VQ++ + + + +++  ++ K K  LE    
Sbjct: 863  ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVK 922

Query: 266  --NRYMKTNTELQIAQTQKK------CNRTE------ELLVEEIEKLRMKTEEEARTHT- 310
              N  ++   E+    T KK      C+  +      EL + ++EK +  TE + +  T 
Sbjct: 923  EMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 982

Query: 311  ------EIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK 364
                  EI   L KE++ L+E  +  ++    D +++++++N+L  +K      + DL  
Sbjct: 983  EMAGLDEIIAKLTKEKKALQEAHQQALD----DLQVEEDKVNSLSKSKVKLEQQVDDLEG 1038

Query: 365  MIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIKLQ 401
             + + ++V    R++ ER+K+K++ DL L  +S++ L+
Sbjct: 1039 SLEQEKKV----RMDLERAKRKLEGDLKLTQESIMDLE 1072



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 57/266 (21%), Positives = 108/266 (40%), Gaps = 28/266 (10%)

Query: 141  VEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSA-TYNSLLQAL 199
            +E NK ++  F+K  R      E   + +          AD++ EL +       + Q L
Sbjct: 1163 IEMNKKREAEFQKMRRDL---EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219

Query: 200  SKER-ENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEM 258
             KE+ E K+   D+ +  E    QII  +  L  V +  + +    NEY   L++  + +
Sbjct: 1220 EKEKSEFKLELDDVTSNME----QIIKAKANLEKVSRTLEDQA---NEYRVKLEEAQRSL 1272

Query: 259  KAKSNLENRYMKTNTELQIAQTQKKC-----NRTEELLVEEIEKLRMKTEEEARTHTEIE 313
               +    +    N EL     +K+       R +    +++E L+ + EEE +    + 
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332

Query: 314  MFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVI 373
              L    Q      +   E+Y+++TE K      L    +       ++A+   +YE   
Sbjct: 1333 HAL----QSARHDCDLLREQYEEETEAKAELQRVLSKANS-------EVAQWRTKYETDA 1381

Query: 374  IEDRIEKERSKKKVKQDLLELKSVIK 399
            I+   E E +KKK+ Q L + +  ++
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVE 1407



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 65/342 (19%), Positives = 143/342 (41%), Gaps = 49/342 (14%)

Query: 84   VQYEGRQSICVKSREMNLEGTNLDKLPMASTITKIPSPLITEEGPNLPEIRHRGRFAVEF 143
            ++ E  + +  K  EM     N  ++     +  + + L  E       +R + +   + 
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRV-----VDSLQTSLDAETRSRNEVLRVKKKMEGDL 1624

Query: 144  NKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQ---ALS 200
            N+M+ +      R      + +K +Q        ++ DT  +L D+   N  L+   A+ 
Sbjct: 1625 NEME-IQLSHANRMAAEAQKQVKSLQ-------SLLKDTQIQLDDAVRANDDLKENIAIV 1676

Query: 201  KERENKMH-----FYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQL 255
            + R N +         ++ + E+ RK     +++LI   +  Q  + SQN  + N     
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLA---EQELIETSERVQL-LHSQNTSLIN----- 1727

Query: 256  QEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEE----------LLVEEIEKLRMKTEEE 305
            Q+ K +S+L      T  + ++ +  ++C   EE          ++ EE++K +  +   
Sbjct: 1728 QKKKMESDL------TQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1781

Query: 306  ARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKM 365
             R    +E  ++  Q +L+E  +  ++   K  +  +  +  L+    ++     +  K 
Sbjct: 1782 ERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG 1841

Query: 366  IREYEQVIIEDRIEKERSKKKV--KQDLLELKSVIKLQAWWR 405
            +R+ E+ I E   + E  KK +   QDL++ K  +K++A+ R
Sbjct: 1842 MRKSERRIKELTYQTEEDKKNLLRLQDLVD-KLQLKVKAYKR 1882



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 53/273 (19%), Positives = 115/273 (42%), Gaps = 27/273 (9%)

Query: 152  KKPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQ-DSATYNSLLQALSKERENKMHFY 210
            K  T +     E + K+  +++   +     + +LQ +    NSL ++  K  +      
Sbjct: 978  KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLE 1037

Query: 211  DIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMK 270
              + +E+K R  +   +++L    K  Q  +         L+++L++ +   N +N  ++
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097

Query: 271  TNTELQIAQTQKKCNRTE---ELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEE-- 325
                L + Q QKK    +   E L EE+E  R    +  +  +++   L +  ++LEE  
Sbjct: 1098 DEQVLAL-QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG 1156

Query: 326  -------------RLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQV 372
                           EF   + D +    Q+E  A    K     H   +A++  + + +
Sbjct: 1157 GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK----KHADSVAELGEQIDNL 1212

Query: 373  -IIEDRIEKERSKKKVKQD--LLELKSVIKLQA 402
              ++ ++EKE+S+ K++ D     ++ +IK +A
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 77/370 (20%), Positives = 150/370 (40%), Gaps = 59/370 (15%)

Query: 64   ISAVLEDTTDQLSILNYIMPVQYEGRQSICVKSREM--NLEGTNLDKLPMASTITKIPSP 121
            +S  LE+ +++L        VQ E  +    + ++M  +LE   L     A+ + K  + 
Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200

Query: 122  LITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSDVIAD 181
             + E G  +  ++ R +  +E  K +   FK          E + K + + +  S  + D
Sbjct: 1201 SVAELGEQIDNLQ-RVKQKLEKEKSE---FKLELDDVTSNMEQIIKAKANLEKVSRTLED 1256

Query: 182  TIKE-----------LQDSATYNSLLQALSKERENKMHFYD-IIAREEKGRKQIISLQKQ 229
               E           L D  T  + LQ  + E   ++   + +I++  +G+   +S  +Q
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGK---LSYTQQ 1313

Query: 230  LINVKKEWQFEVQSQN--------------------EYIANLKDQLQEMKAKSNLENRYM 269
            + ++K++ + E +++N                    E     K +LQ + +K+N E    
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373

Query: 270  KTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEF 329
            +T  E    Q      RTEEL  EE +K   +  ++A    E         +K + RL+ 
Sbjct: 1374 RTKYETDAIQ------RTEEL--EEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425

Query: 330  WMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQ 389
             +E    D E       AL   +       ++  K++ E++Q   E + E E S+K+ + 
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQ-------RNFDKILAEWKQKYEESQSELESSQKEARS 1478

Query: 390  ---DLLELKS 396
               +L +LK+
Sbjct: 1479 LSTELFKLKN 1488



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 50/211 (23%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 193  NSLLQALSKERENKMHFYDIIA----REEKGRKQIISLQKQLINVKKEWQFEVQSQNEYI 248
            N+   AL K++ N   F  I+A    + E+ + ++ S QK+  ++  E     + +N Y 
Sbjct: 1438 NAAAAALDKKQRN---FDKILAEWKQKYEESQSELESSQKEARSLSTEL---FKLKNAYE 1491

Query: 249  ANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVE-EIEKLRMKT---EE 304
             +L + L+  K ++      +   TE Q+ +  K  +  E++  + E+EKL +++   E 
Sbjct: 1492 ESL-EHLETFKRENKNLQEEISDLTE-QLGEGGKNVHELEKVRKQLEVEKLELQSALEEA 1549

Query: 305  EARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAK 364
            EA    E    LR + +  + + E   +  +KD EM+Q + N             Q +  
Sbjct: 1550 EASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH------------QRVVD 1597

Query: 365  MIREYEQVIIEDRIEKERSKKKVKQDLLELK 395
             ++         R E  R KKK++ DL E++
Sbjct: 1598 SLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 61/237 (25%), Positives = 109/237 (45%), Gaps = 29/237 (12%)

Query: 193 NSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLIN-VKKEWQFEVQSQNEYIANL 251
           N   + L +ER+       ++A+++K   + I+ +K  +    +E Q  VQ   E +A  
Sbjct: 699 NRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQ 758

Query: 252 KDQLQ------EMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEE 305
           K+ L+      + KAK  LE+   K   +L+   TQ+K   +E  +  E  K +   E+E
Sbjct: 759 KEVLESSIAHEKRKAKEALESEKRKVQ-DLENHLTQQK-EISESNIAYEKRKAKEAMEKE 816

Query: 306 ARTHTEIEMFL--RKEQQKLEERLEFWMEKYDKDTEMKQNELNALKAT---KASDLA--- 357
            +   ++E  L  +KE+ +L+E+ E  +     D      E    KAT   KA  LA   
Sbjct: 817 KKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKL 876

Query: 358 --HLQDL----AKMIREYEQVIIEDRI------EKERSKKKVKQDLLELKSVIKLQA 402
              L +L     KMI   E++I++ ++      E+E  +   +++++E K  IK  A
Sbjct: 877 NETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHA 933



 Score = 32.7 bits (73), Expect = 0.68
 Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 64/317 (20%)

Query: 140  AVEFNKMQDLVFK-KPTRQTIMTTETLKKIQIDRQFFSDVIADTIKELQDSATYNSLLQA 198
            A E  K + L  K   T   + TT+T   +  +R      +   +++ Q+S  +    + 
Sbjct: 863  ATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEI 922

Query: 199  LSKERENKMHFYDIIAREEKGRK----------QIISLQ--------------------- 227
            +  + + K H   I++ EEK +K          +I +L+                     
Sbjct: 923  MEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTE 982

Query: 228  --------KQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAK-SNLE---NRYMKTNTEL 275
                    + LI+     Q E+ SQ E I  L+  L E  ++ S+L    N   K   E 
Sbjct: 983  SSAKDMAYEHLIDDLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQ 1042

Query: 276  QIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYD 335
             +   Q++ ++   +L E++ ++    E++ R    +E  LR  Q+K   RL+   EK  
Sbjct: 1043 NVVLVQQQ-SKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEK--HRLQLNTEKEQ 1099

Query: 336  K--------DTEMKQNELNALKATKASDLAHLQDLAKMIR--EYEQVIIEDRIEKERSKK 385
            K        DT ++   ++    + + +     DL    +   +E+VI       +R KK
Sbjct: 1100 KPRKKTQTCDTSVQIEPVHTEAFSSSQEQQSFSDLGVRCKGSRHEEVI-------QRQKK 1152

Query: 386  KVKQDLLELKSVIKLQA 402
             + +    +K + K ++
Sbjct: 1153 ALSELRARIKELEKARS 1169



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 19/148 (12%)

Query: 288 EELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNA 347
           EE + +E  + +   EEE +   E+E  L ++++ L + +                E N 
Sbjct: 691 EEYITQERNRAKETLEEERKRMQELESLLAQQKKALAKSI--------------TQEKNR 736

Query: 348 LKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGT 407
           +K     +   +Q+L + +   ++V +E  I  E  K+K K+ L   K   K+Q      
Sbjct: 737 VKEALEEEQTRVQELEERLARQKEV-LESSIAHE--KRKAKEALESEKR--KVQDLENHL 791

Query: 408 MIRREIGGFKMPKDKVDSKDSKGKGKGK 435
             ++EI    +  +K  +K++  K K K
Sbjct: 792 TQQKEISESNIAYEKRKAKEAMEKEKKK 819


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,736,112
Number of Sequences: 37866
Number of extensions: 723500
Number of successful extensions: 5987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 3772
Number of HSP's gapped (non-prelim): 2223
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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