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Search of human proteins with 9945318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9945318 MAX binding protein [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9945318 MAX binding protein [Homo sapiens] 1183 0.0
gi|47132519 Ras association and pleckstrin homology domains 1 is... 87 3e-17
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 86 9e-17
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 86 9e-17
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 82 1e-15
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 82 2e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 81 2e-15
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 80 5e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 7e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 80 7e-15
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 79 1e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 79 1e-14
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 77 3e-14
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 77 3e-14
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 77 3e-14
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 77 3e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens] 77 6e-14
gi|160707881 formin 2 [Homo sapiens] 75 1e-13
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 75 1e-13
gi|153792074 proline rich 12 [Homo sapiens] 75 2e-13
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 73 8e-13
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 73 8e-13
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 72 1e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 72 2e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 72 2e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 72 2e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 72 2e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 70 4e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 70 4e-12
gi|110349719 titin isoform N2-A [Homo sapiens] 69 1e-11
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 1183 bits (3060), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM 60
MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM
Sbjct: 1 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM 60
Query: 61 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ 120
EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ
Sbjct: 61 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ 120
Query: 121 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP 180
PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP
Sbjct: 121 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP 180
Query: 181 GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF 240
GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF
Sbjct: 181 GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF 240
Query: 241 ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 300
ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK
Sbjct: 241 ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 300
Query: 301 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ 360
HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ
Sbjct: 301 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ 360
Query: 361 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 420
PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA
Sbjct: 361 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 420
Query: 421 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ 480
QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ
Sbjct: 421 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ 480
Query: 481 LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT 540
LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT
Sbjct: 481 LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT 540
Query: 541 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 582
VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA
Sbjct: 541 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 582
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 87.4 bits (215), Expect = 3e-17
Identities = 60/202 (29%), Positives = 86/202 (42%), Gaps = 40/202 (19%)
Query: 57 EPRMEAPPLPLSPPAPPPAPPPP--------------------LATPAPLTVIPIPVVTN 96
+P++ PP + PP PPP PPP A P PL + + +T
Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757
Query: 97 SPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSK-- 154
P PPPPP P A P AP +P + S K AP+ ++ PTP P +P +K
Sbjct: 758 VAPPTPPPPP-PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Query: 155 ----ATIPPNGSPKPLQPLPTPVL-------------TIAPHPGVQPQLAPQQPPPPTLG 197
A+ P P P P+P P L ++P P V Q+A Q PPPPT
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 198 TLKLAPAEEVKSSEQKKRPGGI 219
++ P + V ++ + P +
Sbjct: 877 AMESQPLKPVPANVAPQSPPAV 898
Score = 69.7 bits (169), Expect = 7e-12
Identities = 63/226 (27%), Positives = 74/226 (32%), Gaps = 60/226 (26%)
Query: 25 EEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPA 84
EE + R+E L+ + +PPLP PP PPP PPPP P
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 85 PLTVIPIPVVTNSPQPL----------------------PPPPPL-------------PA 109
PL P S P+ PP PP+ P
Sbjct: 648 PLPSQSAPSA-GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN 706
Query: 110 AAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLL------------------- 150
P P P P G+ +K PS PQ P P L
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 151 PDSKATIPPNGSPKPLQ--PLPTPVLTIAPHPGVQPQLAPQQPPPP 194
P A +PP PKPL P PT T+AP V Q AP P PP
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAP---VVTQAAPPTPTPP 809
Score = 57.0 bits (136), Expect = 5e-08
Identities = 68/226 (30%), Positives = 85/226 (37%), Gaps = 45/226 (19%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSV----------------ALPPAH 395
P S +P++L +PP P P PP P P P S + PP
Sbjct: 690 PVMQSQSVKPQIL---VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746
Query: 396 LPVQQQQ--PQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQ 453
L + Q Q Q P P PPPP AP P P LV ST T A+
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP-PKPLVTIPAPTSTKTVAPVVTQAAPPT 805
Query: 454 TVNHVLQGPGGKHIA----HIAPSAPSPAVQLAPAT----------PPIGHITVHPATLN 499
V P K A +I PS P+P V + P T PP ++ P+ +
Sbjct: 806 PTPPV--PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863
Query: 500 HVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKP 545
+A SQ P P P A+ + L N A PPA V AKP
Sbjct: 864 QIA---SQFPPPPTPPAME--SQPLKPVPAN-VAPQSPPA-VKAKP 902
Score = 52.8 bits (125), Expect = 9e-07
Identities = 43/140 (30%), Positives = 54/140 (38%), Gaps = 7/140 (5%)
Query: 352 PPKLSHRPQPELLKSTLPP-PSTTPAPLPPHPHPHPHSVAL--PPAHL-PVQQQQPQQKT 407
PP + QP S +PP P T P P+PP P S PP+ L PV Q +
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P PP PPA +Q L P PA++ A + S I + P +
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANV---APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924
Query: 468 AHIAPSAPSPAVQLAPATPP 487
P PSP P PP
Sbjct: 925 LVFPPPPPSPVPAPPPPPPP 944
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/176 (28%), Positives = 60/176 (34%), Gaps = 48/176 (27%)
Query: 58 PRMEAPPLPLSPPA------------PPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
P PP+P+ PP P P P P VV PPPP
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP------------SVVKQIASQFPPPP 873
Query: 106 PLPA-AAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP--APLLPDSKATIPPNGS 162
PA +QPL P A P + K P PS VP+P P P+S PP
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAK-PKWQPSSIPVPSPDFPPPPPESSLVFPP--- 929
Query: 163 PKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGG 218
P P+PV AP PPPPT K + + PGG
Sbjct: 930 -----PPPSPV------------PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG 968
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 35/143 (24%)
Query: 50 AHTLPVEEPRMEAPPL--PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPL 107
A+ P P ++A P P S P P P PPP P V P P + P P PPPPP
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP--PPESSLVFPPPPPSPVPAPPPPPPPT 945
Query: 108 --------------------PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT-- 145
P +P P R ++ + G P P RP V +
Sbjct: 946 ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE----HPEPKRPSVDSLV 1001
Query: 146 -----PAPLLPDSKATIPPNGSP 163
PA SK T+PP +P
Sbjct: 1002 SKFTPPAESGSPSKETLPPPAAP 1024
Score = 46.6 bits (109), Expect = 6e-05
Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 23/185 (12%)
Query: 52 TLPVEEPRM-EAPPLPLSP--------------PAPPPAPPPPLATPAPLTVIPIPVVTN 96
TLP ++ + PP PLSP P PPA P P V P
Sbjct: 839 TLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAV 898
Query: 97 SPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDS--- 153
+P P +P + P P + +LV P PAP P P +P P S
Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958
Query: 154 --KATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSE 211
T P G P P P +I G + P++P +L + PAE S+
Sbjct: 959 KTSKTSSPGGKKPP--PTPQRNSSIKSSSGAE-HPEPKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 212 QKKRP 216
+ P
Sbjct: 1016 ETLPP 1020
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/185 (23%), Positives = 63/185 (34%), Gaps = 26/185 (14%)
Query: 341 EDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQ 400
E M L PP PQP+++ + P P PP P P P PP P
Sbjct: 596 ESMNRPYTSLVPPL---SPQPKIVTPYTASQPSPPLPPPPPPPPPP-----PPPPPPPPP 647
Query: 401 QQPQQKTPLPAPPPPPAAPAQT---LVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNH 457
P Q P P T L A H A + + + + ++ N
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 458 VLQGP--------GGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLP 509
V+ P G +A + P+ +P++ A PP P ++ V H+ P
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP-------PLKIHQVQHITQVAP 760
Query: 510 LYPQP 514
P P
Sbjct: 761 PTPPP 765
Score = 40.4 bits (93), Expect = 0.005
Identities = 51/208 (24%), Positives = 69/208 (33%), Gaps = 69/208 (33%)
Query: 54 PVEEPRMEAPPLPLSP-PAPPPAPPP--------------------------PLATPAPL 86
P E + PP P SP PAPPP PPP P TP
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978
Query: 87 TVIPIPVVTNSPQP-------------------------LPPP--PP-----------LP 108
+ I P+P LPPP PP LP
Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP 1038
Query: 109 AAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQP 168
Q ++ + P L G S+ E PS P P P+++ +PP P
Sbjct: 1039 GVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP---PETELPLPPIEIPAVFSG 1095
Query: 169 LPTP-VLTIAPHPGVQPQLAPQQPPPPT 195
+P V + P P +++ ++ PPPT
Sbjct: 1096 NTSPKVAVVNPQPQQWSKMSVKKAPPPT 1123
Score = 40.0 bits (92), Expect = 0.006
Identities = 57/222 (25%), Positives = 79/222 (35%), Gaps = 35/222 (15%)
Query: 366 STLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVP 425
S +PP S P + P+ P S LPP P P PPPPP P P
Sbjct: 604 SLVPPLSPQPKIVTPYTASQP-SPPLPP--------------PPPPPPPPPPPPPPPPPP 648
Query: 426 APAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPAT 485
P+ +AG + + +T I + + Q G P S +V+
Sbjct: 649 LPSQSAPSAGSAAPMFVKYST-----ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703
Query: 486 PPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHT-----LSHQQVNGTAGLGPPAT 540
PP G + P + L P P A S + L QV + PP T
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP-T 762
Query: 541 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 582
P + A + PQ P +VT+P+ P ST +A
Sbjct: 763 PPPPPPIPAPL--PPQ------APPKPLVTIPA-PTSTKTVA 795
Score = 39.7 bits (91), Expect = 0.008
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 17/69 (24%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPA 411
PP + +P+ + PS+ P P P P P P S + P P +P+PA
Sbjct: 895 PPAVKAKPKWQ--------PSSIPVPSPDFPPPPPESSLVFP---------PPPPSPVPA 937
Query: 412 PPPPPAAPA 420
PPPPP A
Sbjct: 938 PPPPPPPTA 946
Score = 39.7 bits (91), Expect = 0.008
Identities = 47/201 (23%), Positives = 72/201 (35%), Gaps = 24/201 (11%)
Query: 68 SPPAPPPAPPPPLATPAPLTVIPIPVV---TNSPQPL---PPPPPLPAAAQPLPLAPRQP 121
SPP+ PPPP T PL I IP V SP+ P P + P +P
Sbjct: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRP 1125
Query: 122 ALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPG 181
+ L+ E + P+ V P P S ++ P + L +I H
Sbjct: 1126 KRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK--SITRHGS 1183
Query: 182 VQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFE 241
+ +++ +P P E+ S +QK GG +H+ +
Sbjct: 1184 LSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGG---------------SHISG-YA 1227
Query: 242 TLKRNIPNVDDKKTSNLSVLR 262
TL+R P K+ N + R
Sbjct: 1228 TLRRGPPPAPPKRDQNTKLSR 1248
Score = 33.1 bits (74), Expect = 0.72
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 348 AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
+G G + P P PPP T PLPP P S P + V QPQQ +
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSP-KVAVVNPQPQQWS 1112
Query: 408 PLPA-PPPPPAAP 419
+ PPP P
Sbjct: 1113 KMSVKKAPPPTRP 1125
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 85.9 bits (211), Expect = 9e-17
Identities = 94/344 (27%), Positives = 135/344 (39%), Gaps = 78/344 (22%)
Query: 17 AQQQQRAREEQ-----------ERLRLEQEREQEQKKANSLARLAHTLPVEEPRME---- 61
+++QQ A E+Q E +L +E E +K+ SL+ A T+P P
Sbjct: 516 SEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP 575
Query: 62 APPLP----------------LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
APPLP +PP PPP PPPP P + + P + + PPP
Sbjct: 576 APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGG-TAISPPP 634
Query: 106 PLPAAAQPLPLAPRQPALVGAP-------GLSIKEPAPLPSRPQVPTPAPLLPDSKATIP 158
PL A +P P P VG P G +I P PLP ++P P P LP S P
Sbjct: 635 PLSGDA-TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 693
Query: 159 P-------NGSPKPLQPLP-----TPVLTIAPHPGVQPQLAPQ-QPPPPTLG-------- 197
P G P P PLP P PG+ P PPPP G
Sbjct: 694 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753
Query: 198 -TLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTS 256
L P + K Q +RP ++ V L ++CF T + +D+ +
Sbjct: 754 LPFGLTPKKLYKPEVQLRRPN--WSKLVAEDLS-------QDCFWTKVK-----EDRFEN 799
Query: 257 NLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 300
N + L + S + K + + + E +K ++++ ELK
Sbjct: 800 NELFAKLTLTF--SAQTKTSKAKKDQEGGEEKKSVQKKKVKELK 841
Score = 47.8 bits (112), Expect = 3e-05
Identities = 54/233 (23%), Positives = 85/233 (36%), Gaps = 58/233 (24%)
Query: 271 LKRKEKEYEHEMERLAREKIAT---QQRLAELKHELSQWMDVL--EIDRVLRQTGQPEDD 325
+K+ E ++E +++ L EK A +Q++A K +L + L E+ ++ ++ + +
Sbjct: 493 MKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKE 552
Query: 326 QASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPH-P 384
AS S A+ T+PP + AP+PP P P
Sbjct: 553 MASLSAAA--------------------------------ITVPPSVPSRAPVPPAPPLP 580
Query: 385 HPHSVALPPAHLPVQQQQPQQKTPLPAPPP----------PPAAPAQTLVPAPAHLVATA 434
+PP P P P P PPP PP+ P T + P L
Sbjct: 581 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL---- 636
Query: 435 GGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
G +T+ I + + + PGG I P P P P PP
Sbjct: 637 SGDATIPPPPPLPEGVGIPSPSSL---PGG---TAIPPPPPLPGSARIPPPPP 683
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTP 408
G+G P S P + P P + P PP P P + PP LP + P P
Sbjct: 651 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 710
Query: 409 LPAP---PPPPAAPAQTLVPAP 427
LP PPPP P +P P
Sbjct: 711 LPGGPGIPPPPPFPGGPGIPPP 732
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 359 PQPELLKSTLPPPSTTPAPLP-PHPHPHPHSVALPPAH-LPVQQQQPQQKTPLPA----- 411
P P +T+PPP P + P P P A+PP LP + P PLP
Sbjct: 633 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP 692
Query: 412 PPPPPAAPAQTLVPAPAHLVATAG 435
PPPPP + P P L G
Sbjct: 693 PPPPPLPGEAGMPPPPPPLPGGPG 716
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 85.9 bits (211), Expect = 9e-17
Identities = 94/344 (27%), Positives = 135/344 (39%), Gaps = 78/344 (22%)
Query: 17 AQQQQRAREEQ-----------ERLRLEQEREQEQKKANSLARLAHTLPVEEPRME---- 61
+++QQ A E+Q E +L +E E +K+ SL+ A T+P P
Sbjct: 525 SEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP 584
Query: 62 APPLP----------------LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
APPLP +PP PPP PPPP P + + P + + PPP
Sbjct: 585 APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGG-TAISPPP 643
Query: 106 PLPAAAQPLPLAPRQPALVGAP-------GLSIKEPAPLPSRPQVPTPAPLLPDSKATIP 158
PL A +P P P VG P G +I P PLP ++P P P LP S P
Sbjct: 644 PLSGDA-TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 702
Query: 159 P-------NGSPKPLQPLP-----TPVLTIAPHPGVQPQLAPQ-QPPPPTLG-------- 197
P G P P PLP P PG+ P PPPP G
Sbjct: 703 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762
Query: 198 -TLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTS 256
L P + K Q +RP ++ V L ++CF T + +D+ +
Sbjct: 763 LPFGLTPKKLYKPEVQLRRPN--WSKLVAEDLS-------QDCFWTKVK-----EDRFEN 808
Query: 257 NLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 300
N + L + S + K + + + E +K ++++ ELK
Sbjct: 809 NELFAKLTLTF--SAQTKTSKAKKDQEGGEEKKSVQKKKVKELK 850
Score = 47.8 bits (112), Expect = 3e-05
Identities = 54/233 (23%), Positives = 85/233 (36%), Gaps = 58/233 (24%)
Query: 271 LKRKEKEYEHEMERLAREKIAT---QQRLAELKHELSQWMDVL--EIDRVLRQTGQPEDD 325
+K+ E ++E +++ L EK A +Q++A K +L + L E+ ++ ++ + +
Sbjct: 502 MKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKE 561
Query: 326 QASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPH-P 384
AS S A+ T+PP + AP+PP P P
Sbjct: 562 MASLSAAA--------------------------------ITVPPSVPSRAPVPPAPPLP 589
Query: 385 HPHSVALPPAHLPVQQQQPQQKTPLPAPPP----------PPAAPAQTLVPAPAHLVATA 434
+PP P P P P PPP PP+ P T + P L
Sbjct: 590 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL---- 645
Query: 435 GGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
G +T+ I + + + PGG I P P P P PP
Sbjct: 646 SGDATIPPPPPLPEGVGIPSPSSL---PGG---TAIPPPPPLPGSARIPPPPP 692
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTP 408
G+G P S P + P P + P PP P P + PP LP + P P
Sbjct: 660 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 719
Query: 409 LPAP---PPPPAAPAQTLVPAP 427
LP PPPP P +P P
Sbjct: 720 LPGGPGIPPPPPFPGGPGIPPP 741
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 359 PQPELLKSTLPPPSTTPAPLP-PHPHPHPHSVALPPAH-LPVQQQQPQQKTPLPA----- 411
P P +T+PPP P + P P P A+PP LP + P PLP
Sbjct: 642 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP 701
Query: 412 PPPPPAAPAQTLVPAPAHLVATAG 435
PPPPP + P P L G
Sbjct: 702 PPPPPLPGEAGMPPPPPPLPGGPG 725
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 82.4 bits (202), Expect = 1e-15
Identities = 153/622 (24%), Positives = 211/622 (33%), Gaps = 167/622 (26%)
Query: 53 LPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP-LPPPPPLPAAA 111
LP + P LP P PP PP T P V+P P PQP LPP P LP
Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP-PQPMLPPQPVLPPQPALPVRP 1002
Query: 112 QPL-PLAPRQPALVGAPG--LSIKEPAPL--------------------PSRPQVPTPA- 147
+PL P P Q A PG + + PAP P P+V PA
Sbjct: 1003 EPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAA 1062
Query: 148 ----PLLPDSKATI---------------PPNGSPKP-----LQPLPTPVLTIAPHPGVQ 183
P P S AT+ PP P P P PT LT+ P VQ
Sbjct: 1063 PELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP---VQ 1119
Query: 184 PQLAPQQPPP------PTLGTLKLAPAEEVKSSEQKKRPGG-IGTREVHNKLEKNRRAHL 236
+ A Q PP + G + +E+ S + GG + R ++ RA
Sbjct: 1120 EEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARS 1179
Query: 237 KECFETLKR----NIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIAT 292
++ + R N+ N DK +++ K ++ +++ A ++IAT
Sbjct: 1180 RQERASRPRLTILNVCNTGDKMVE---------CQLETHNHKMVTFKFDLDGDAPDEIAT 1230
Query: 293 QQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRA---G 349
++E D +L+ + +Q + ED + ED + DR G
Sbjct: 1231 Y---------------MVEHDFILQAERETFIEQMK-DVMDKAEDMLSEDTDADRGSDPG 1274
Query: 350 LGPPKLS--------------------------------------HRPQPELLKSTLPPP 371
PP LS P PE +S+ P P
Sbjct: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334
Query: 372 STTPAPLPPH------PHPHPHSVALPPAHLPVQQ-------QQPQQKTPLP-APPPPP- 416
++ LPP P+ S P+ L QQ P P P AP PP
Sbjct: 1335 LSS---LPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPV 1391
Query: 417 -------AAPAQTLVPAPAHLVAT-AGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIA 468
AAPA + +P PA A+ AGG T T+ S H +
Sbjct: 1392 TALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVV 1451
Query: 469 HIAPSAPSP--------AVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPV-AVSH 519
+AP P+P + P PP + H T LG PL P V AVS
Sbjct: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPA--LGQPAPLLPAAVGAVSL 1509
Query: 520 IAHTLSHQQVNGTAGLGPPATV 541
L + T PP+ +
Sbjct: 1510 ATSQLPSPPLGPTVPPQPPSAL 1531
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/175 (31%), Positives = 70/175 (40%), Gaps = 18/175 (10%)
Query: 38 QEQKKANSLARLAHTLP------VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPI 91
Q +++ L LA P P E P LP S P+ P A P+ +P
Sbjct: 629 QSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPA 688
Query: 92 PVVTNS-PQPLPPP-----PPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPS----RP 141
P S Q P P P LP + P+P P QPA G + +P PLP +P
Sbjct: 689 PACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQP 748
Query: 142 QVPTP--APLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPP 194
VP P LP A G+P L+PL P + P V PQ+ P PP
Sbjct: 749 VVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP 803
Score = 65.1 bits (157), Expect = 2e-10
Identities = 59/177 (33%), Positives = 69/177 (38%), Gaps = 49/177 (27%)
Query: 64 PLPLSP--PAPPPAPPPPLATPAPL--TVIPIPVVTNSPQPLPPPPPLPAAAQ------- 112
P+P P PAPP PPPLA P PL + P PVV P P PP L A+Q
Sbjct: 716 PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQL 775
Query: 113 ---------------------PLPLAPRQPALVGAPGLSIKEP-APLPSRPQVP-----T 145
P+P+ P L G GL P P + P VP +
Sbjct: 776 KPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFS 835
Query: 146 PAPLLPDSKATIPPNGSPKPLQ----------PLPTPVLTIAPH-PGVQPQLAPQQP 191
PA +LP A +PP PLQ PL P TI P+ P P LA P
Sbjct: 836 PAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPP 892
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/151 (33%), Positives = 62/151 (41%), Gaps = 32/151 (21%)
Query: 51 HTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP-LPPPPPLPA 109
H+ + P P AP PP P T + P PQP LPP P LP
Sbjct: 900 HSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATP-------PQPALPPQPTLP- 951
Query: 110 AAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT--PAPLLPDSKATIPPNGSPKPLQ 167
P P+ P QP L P L P P+RP P P P+LP P+P+
Sbjct: 952 ---PQPVLPPQPTLPPQPVLP-----PQPTRPPQPVLPPQPMLP-----------PQPVL 992
Query: 168 PLPTPVLTIAPHPGVQPQLAPQQPPPPTLGT 198
P P P L + P P +QP L Q P T G+
Sbjct: 993 P-PQPALPVRPEP-LQPHLPEQAAPAATPGS 1021
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 43 ANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATP------APLTVIPIPVVTN 96
A+ + A P++ P+ PL PP PP P P TP P + +P T
Sbjct: 766 ASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV 825
Query: 97 SPQPLP----PPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPD 152
P P P P LP+ A PLP P PAL P ++K P P P P ++P+
Sbjct: 826 PPVPPPQYFSPAVILPSLAAPLP--PASPAL---PLQAVKLPHP-PGAPLAMPCRTIVPN 879
Query: 153 SKATI------PPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP 193
+ ATI PP + + + +P PQ+AP PP
Sbjct: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPP 926
Score = 55.1 bits (131), Expect = 2e-07
Identities = 81/266 (30%), Positives = 101/266 (37%), Gaps = 52/266 (19%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPA-PLPPH--PHPHPHSVALPPAHL-PVQQQQ-- 402
G PP L+ QP L L P P P+PPH P+ P S PA L P+Q Q
Sbjct: 728 GQQPPPLA---QPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAP 784
Query: 403 -------PQQKTPLPAPPP----------PPAAP-----AQTLVPAPAHLVATAGGGSTV 440
P Q P+P PP PPA P VP P + S
Sbjct: 785 LQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA 844
Query: 441 IAHTATTHASVIQTVNHVLQGPGGKHIA----HIAPSAPSPAVQLAPATPPIGHITVHPA 496
+ A +Q V L P G +A I P+AP+ LA A P + +++H A
Sbjct: 845 APLPPASPALPLQAVK--LPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSA 902
Query: 497 TLNHVAHLGSQLPLYPQPVAVSHIAHT----LSHQQVNGTAGLGPPATVMAKPAVGAQVV 552
VA L Q P+Y P A +A T H V P + +P + Q V
Sbjct: 903 ----VAQLPGQ-PVY--PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPV 955
Query: 553 HHPQ--LVGQTVLNPVTMVTMPSFPV 576
PQ L Q VL P T P PV
Sbjct: 956 LPPQPTLPPQPVLPP--QPTRPPQPV 979
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/154 (29%), Positives = 62/154 (40%), Gaps = 7/154 (4%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLA 117
P + AP P SP P A P APL + +V N+P +P P L +
Sbjct: 841 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 900
Query: 118 PRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPK----PLQPLPTPV 173
L G P P P+ P+P + + +AT P P P QP+ P
Sbjct: 901 SAVAQLPGQPVYPAAFPQMAPT-DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQ 959
Query: 174 LTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV 207
T+ P P + PQ P +PP P L + P + V
Sbjct: 960 PTLPPQPVLPPQ--PTRPPQPVLPPQPMLPPQPV 991
Score = 50.1 bits (118), Expect = 6e-06
Identities = 51/144 (35%), Positives = 60/144 (41%), Gaps = 20/144 (13%)
Query: 81 ATPAPLTVIPIPVVTNSPQPLPPPPPL-----PAAAQPLPLAPRQPALVGAPGLSIKEPA 135
A P+P + P V+ P P L P AA LP+ PA P L P
Sbjct: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS-VPAPACPPSLQQHFPD 701
Query: 136 PL----PSRPQVPTPAPLLPDSKATIPPNGSPKPL-QPLPTPVLTIAPHPGVQPQLAPQQ 190
P P P TP P P A PP P PL QP P P + +AP P + P Q
Sbjct: 702 PAMSFAPVLPPPSTPMPTGPGQPA--PPGQQPPPLAQPTPLPQV-LAPQP-----VVPLQ 753
Query: 191 PPPPTLGTLKLAPAEEVKSSEQKK 214
P PP L LAPA +V + Q K
Sbjct: 754 PVPPHLPPY-LAPASQVGAPAQLK 776
Score = 49.7 bits (117), Expect = 7e-06
Identities = 58/218 (26%), Positives = 81/218 (37%), Gaps = 27/218 (12%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAP-LPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP 410
PP H Q +++T P P+ P P LPP P P P LP Q +P P P
Sbjct: 925 PPSPHHTVQN--MRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRP----PQP 978
Query: 411 APPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHI 470
PP P P Q ++P L + H A + +L G + +
Sbjct: 979 VLPPQPMLPPQPVLPPQPALPVRP---EPLQPHLPEQAAPAATPGSQILLGHPAPYAVDV 1035
Query: 471 APSAPS-PAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVA-VSHIAHTLSHQQ 528
A P+ P A +PP+ + + A LP +P +A VS ++ Q
Sbjct: 1036 AAQVPTVPVPPAAVLSPPLPEVLLPAAP--------ELLPQFPSSLATVSASVQSVPTQ- 1086
Query: 529 VNGTAGLGPPATVMAKPAVGAQVVHHPQLVGQTVLNPV 566
TA L PPA P G + P Q + PV
Sbjct: 1087 ---TATLLPPAN---PPLPGGPGIASPCPTVQLTVEPV 1118
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 67 LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPP-PPLPAAAQPLPLAPRQPALVG 125
L+P P P AP +P P +P+P P P PA QP PL P A VG
Sbjct: 1453 LAPCTPAPEAASTRDASAPREPLPPP----APEPSPHSGTPQPALGQPAPLLP---AAVG 1505
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPP 159
A L+ + P P VP P +S PP
Sbjct: 1506 AVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL 114
V E E PP + AP P PP PL L ++ + P P PAA
Sbjct: 46 VVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-PAALVAQ 104
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPT-PAP 148
P AP PA G + +EP P P V T PAP
Sbjct: 105 PGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAP 139
Score = 37.0 bits (84), Expect = 0.050
Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 16/117 (13%)
Query: 268 IQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQA 327
+ + K+ + ++ +L E + A+LK L+Q L+QT + +D +A
Sbjct: 2111 VNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQ----------LKQTQKLQDMEA 2160
Query: 328 STSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHP 384
A+ GE M RAG+G P+L P P ST P P P P P
Sbjct: 2161 QAGWAAPGEARA---MTAPRAGVGMPRLPPAPGP---LSTTVIPGAAPTLSVPTPDP 2211
Score = 31.6 bits (70), Expect = 2.1
Identities = 59/234 (25%), Positives = 76/234 (32%), Gaps = 33/234 (14%)
Query: 361 PELLKSTLPPPSTTPAPLPPHPHPH-PHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAP 419
P L ++P P+ P+ P P + LPP P+ P Q P PPP A P
Sbjct: 679 PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG-PGQPAPPGQQPPPLAQP 737
Query: 420 AQ-----------TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQ--GPGGKH 466
L P P HL S V A + Q L P
Sbjct: 738 TPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797
Query: 467 IAHIAPSAPSPAVQ-LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLS 525
I + P P + L PA P + TV P LP P+ + A L
Sbjct: 798 IPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQ 857
Query: 526 HQQVNGTAGL-----------GPPATV----MAKPAVGAQVVHH--PQLVGQTV 562
++ G PAT+ +A P V A +H QL GQ V
Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPV 911
Score = 31.6 bits (70), Expect = 2.1
Identities = 21/67 (31%), Positives = 27/67 (40%)
Query: 37 EQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTN 96
+Q QK + A+ P E M AP + P PPAP P T P + V T
Sbjct: 2150 KQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTP 2209
Query: 97 SPQPLPP 103
P+ P
Sbjct: 2210 DPESEKP 2216
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 81.6 bits (200), Expect = 2e-15
Identities = 59/171 (34%), Positives = 74/171 (43%), Gaps = 30/171 (17%)
Query: 52 TLPVEEPRMEAPPLPLSPPAPPPAPPP---------PLATPAPLT---VIPIPVVTNSPQ 99
TLP+ P P+ PPAP A P PL+ PAP+ ++P+ V T+ P
Sbjct: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPA 247
Query: 100 PLPPPPPLPAAAQPLPLAP-----RQPALVGA-----------PGLSIKEPAPLPSRPQV 143
P PP P+PA A P P P V A P + AP P+ V
Sbjct: 248 PSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSV 307
Query: 144 PTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPP 194
P AP L +A +PP+ L P+PTPVL AP P P AP P P
Sbjct: 308 PVSAPPLALIQAPVPPSAPTLVLAPVPTPVL--APMPASTPPAAPAPPSVP 356
Score = 68.6 bits (166), Expect = 2e-11
Identities = 106/443 (23%), Positives = 156/443 (35%), Gaps = 98/443 (22%)
Query: 48 RLAHTLPVEEPRMEAPPLPLSPPAPPPAPP-----PPLATPAPLTV-IPIPVVTNSPQPL 101
++A ++P P + P+P PAPP P PL+ A + V +P + P PL
Sbjct: 240 QVATSVPAPSPPLA--PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPL 297
Query: 102 PPPPP----LPAAAQPL-----PLAPRQPALVGAP-------GLSIKEPAPLPSRPQVPT 145
P P +P +A PL P+ P P LV AP + P P+ P VP
Sbjct: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPM 357
Query: 146 PAPLL---PDSKATIPPNGSPKPL-QPLPTPVLTIA--PHPGVQPQLAPQQPPPPTLGTL 199
P P P S T+ P +P P+ P P P+ T A P P P P P P +L
Sbjct: 358 PTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSL 417
Query: 200 KLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLK-RNIP-NVDDKKTSN 257
++ +K P V + C + L +P + T
Sbjct: 418 SRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLT 477
Query: 258 LSVLRTALR------YIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLE 311
L VL + L+ + S + + Y + R + + +L LE
Sbjct: 478 LPVLPSYLQDRCLPGVLASPELRSYPYAFSVAR----PLTSDSKLVS-----------LE 522
Query: 312 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP 371
++R+ P + ++T D + + + K+ PQP LP P
Sbjct: 523 VNRL------PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQP-----LLPAP 571
Query: 372 STTPAPLPPHPHPHPH---------SVALPPAHLPVQQQQP------------------- 403
S + A PPHP P SV P P Q ++
Sbjct: 572 SGSSA--PPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSN 629
Query: 404 QQKTPLP----APPPPPAAPAQT 422
+QK PLP PP P P T
Sbjct: 630 RQKLPLPNQRKTPPMPVLTPVHT 652
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/219 (26%), Positives = 76/219 (34%), Gaps = 26/219 (11%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPH-PHPHPHSVALP---PAHLPVQQQQPQ 404
G G P P S LP P PAP PH P + +P PA +P P
Sbjct: 180 GTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPV 239
Query: 405 QKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGG 464
Q P PP AP L PAP + + + + ASV+ V G
Sbjct: 240 QVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPL-----SVSASVLVPVPASAPPSGP 294
Query: 465 KHIAHIAP-------SAPSPAVQLAPATPPIGHITVHPATLNHVAHL-GSQLPLYPQPVA 516
++ AP SAP A+ AP P + + P +A + S P P P +
Sbjct: 295 VPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPS 354
Query: 517 VSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQVVHHP 555
V T GPP+T PA V P
Sbjct: 355 V---------PMPTPTPSSGPPSTPTLIPAFAPTPVPAP 384
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 1/69 (1%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAA 418
P P + P P+ TPA +P P P S +L P Q QK PL P
Sbjct: 386 PAPIFTPAPTPMPAATPAAIPTSA-PIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLT 444
Query: 419 PAQTLVPAP 427
P+Q LV P
Sbjct: 445 PSQPLVYIP 453
Score = 38.1 bits (87), Expect = 0.022
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 12/79 (15%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPA- 417
P P P P + P P P P + L PA P TP+PAP P P
Sbjct: 340 PMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAP---------TPVPAPTPAPIF 390
Query: 418 APAQTLVPA--PAHLVATA 434
PA T +PA PA + +A
Sbjct: 391 TPAPTPMPAATPAAIPTSA 409
Score = 33.1 bits (74), Expect = 0.72
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 128 GLSIKEPAPLPSRPQVPTPAPLLPDSKATIP-PNGSPKPLQPLPTPVLTIAPHPGVQP-Q 185
G+ ++ PL + P PAP+ P + + P+ P Q +P V PH G+ P Q
Sbjct: 182 GVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQ-VPLSVPAPVPHSGLVPVQ 240
Query: 186 LAPQ--QPPPPTLGTLKLAPA 204
+A P PP LAPA
Sbjct: 241 VATSVPAPSPPLAPVPALAPA 261
Score = 29.6 bits (65), Expect = 8.0
Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 13/111 (11%)
Query: 50 AHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPA 109
A LP +P + AP +PP P P +V + PL PP L
Sbjct: 558 AKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSV--------TFSPLKSPPQLER 609
Query: 110 AAQPLPLAPRQPALVGAPGLSIKEPAPLPSR---PQVPTPAPLLPDSKATI 157
P P + S ++ PLP++ P +P P+ SKA +
Sbjct: 610 EMASPPECSEMP--LDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALL 658
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 81.3 bits (199), Expect = 2e-15
Identities = 60/177 (33%), Positives = 78/177 (44%), Gaps = 16/177 (9%)
Query: 46 LARLAHTLPVEEPRMEAPPLPLSPPAPPPAPP-PPLATPAPLTVIPIPV-VTNSPQPLPP 103
L+ LA P P + PPL +PP+PP +PP PLATP+P + V + +P PP
Sbjct: 611 LSPLATPPPQAPPXLALPPLQ-APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 104 PPPLPAAAQPLPLAPRQPALV----GAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPP 159
PP+ A P P P+ P L+ PL P P P+ P AT PP
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLA---APPLQVPPSPPASPPMSP--SATPPP 724
Query: 160 NGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P PL P L + P P P ++P PPP + L AP +V S P
Sbjct: 725 QAPP----PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Score = 77.8 bits (190), Expect = 3e-14
Identities = 54/146 (36%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPP-PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
P P + APPL + PP+PP +PP P ATP P +P P++ P +PP PP
Sbjct: 724 PQAPPPLAAPPLQV-PPSPPASPPMSPSATPPPR--VP-PLLAAPPLQVPPSPPASLPMS 779
Query: 113 PLPLAPRQPALVGAPGLSIKEPAPLPSRP-QVPTPAPLLPDSKATIPPNGSPKPLQP--L 169
PL P Q P L+ LPS P P AP P + + P +P P P L
Sbjct: 780 PLAKPPPQ----APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 170 PTPVLTIAPHPGVQPQL-APQQPPPP 194
P+L + P P P L AP++PP P
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTP 861
Score = 77.0 bits (188), Expect = 4e-14
Identities = 62/200 (31%), Positives = 77/200 (38%), Gaps = 42/200 (21%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQ--------PL---- 101
P+ P +E PP P P P APP PL TP P T P + T PQ PL
Sbjct: 552 PLTTPHLETPPCPA--PCPLQAPPSPLTTPPPET--PSSIATPPPQAPPALASPPLQGLP 607
Query: 102 ---------PPP-------------PPLPAAAQPL-PLAPRQPALVGAPGLSIKEPAPLP 138
PPP PP P A+ PL PLA P A + + + AP
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-APFS 666
Query: 139 SRPQVPTPAPLLPDSKATIPPNGSPKPLQP--LPTPVLTIAPHPGVQPQLAPQQPPPPTL 196
P P AP P + + P+ +P P L P L + P P P ++P PPP
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 197 GTLKLAPAEEVKSSEQKKRP 216
AP +V S P
Sbjct: 727 PPPLAAPPLQVPPSPPASPP 746
Score = 75.5 bits (184), Expect = 1e-13
Identities = 61/164 (37%), Positives = 74/164 (45%), Gaps = 26/164 (15%)
Query: 58 PRMEAPPL--PLSPPAPPPAPP---PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
P + APPL P SPPA PP P PP P PL P+ V P P PP P+A
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV---PPSPPASPPMSPSATP 753
Query: 113 PLPLAPRQPALVGAPGLSI--KEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLP 170
P PR P L+ AP L + PA LP P + P P P + AT PLQ LP
Sbjct: 754 P----PRVPPLLAAPPLQVPPSPPASLPMSP-LAKPPPQAPPALAT-------PPLQALP 801
Query: 171 TPVLTI---AP-HPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSS 210
+P + AP P ++P PPP + AP +V S
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Score = 67.0 bits (162), Expect = 5e-11
Identities = 50/140 (35%), Positives = 59/140 (42%), Gaps = 18/140 (12%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLATPAP--LTVIPIPVVTNSPQPLPPP-PPLPAAAQPL 114
P PP + PA P PLATP+P P+P N+ PLP PP P A PL
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL 174
PLAP P+ P L + P P P T PP +P LQ +P P+
Sbjct: 342 PLAPPSPS----------APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP-PIQ 390
Query: 175 TIAPHPGVQPQLAPQQPPPP 194
PH P L Q PP P
Sbjct: 391 --VPHSLTSPSL--QAPPSP 406
Score = 62.8 bits (151), Expect = 9e-10
Identities = 69/216 (31%), Positives = 86/216 (39%), Gaps = 45/216 (20%)
Query: 32 LEQEREQEQKKANSLARLAHTLPVEEPRMEAP-PLPLSPPAPPPAPPPPLATPAPLTVIP 90
L Q Q S +R A T P + P ++AP LP SPP P +PLT+ P
Sbjct: 430 LTMSPRQTQASLTSPSRPAST-PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 91 I----PVVTNSPQ-PLPP--PPPL-------PAAAQPLPLAPRQPALVGAPGLS------ 130
+ + ++SPQ PL PPL P + Q P + P L P L+
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 131 ----------IKEPAPLPSRPQVP-----TPAPLLPDSKATIPPNGSP----KPLQPLPT 171
P P P Q P TP P P S AT PP P PLQ LP+
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 172 PVLT--IAPHPGVQPQLA--PQQPPPPTLGTLKLAP 203
P L+ P P P LA P Q PP + L+P
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/160 (34%), Positives = 67/160 (41%), Gaps = 47/160 (29%)
Query: 54 PVEEPRMEAPPL--PLSPPA---------PPPAPPPPLATPAPLTVIPIPVVTNSPQ-PL 101
P P + APPL P SPPA PPP PP LATP PL +P P + Q P
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASFPGQAPF 813
Query: 102 PPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPL------PSRPQVPTPAPLLPDSKA 155
P LP + P P+ P ++ AP L + P P RP PTP PD+
Sbjct: 814 SPSASLPMSPLATP-PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPG---PDTSV 867
Query: 156 TIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPT 195
+ P LT+A LAP PPPP+
Sbjct: 868 S--------------GPRLTLA--------LAPGPPPPPS 885
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 20/167 (11%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQP 113
PV P A PLP + P P PPLATP PL P P S Q LP PP P + P
Sbjct: 316 PVPPPDNAATPLPATLP-----PSPPLATPLPLAP-PSPSAPPSLQTLPSPPATPPSQAP 369
Query: 114 LPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT----PAPLLPDSKATIPPNGSPKPLQPL 169
+ P + P L P +P P+ P+PL S GSP LQ
Sbjct: 370 PSMT--TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP-TLQAT 426
Query: 170 PTPVLTIAPHPGVQPQLAPQQP------PPPTLGTLKLAPAEEVKSS 210
+ LT++P +P +P PP L L + +++S
Sbjct: 427 HS-FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
Score = 53.1 bits (126), Expect = 7e-07
Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 33/183 (18%)
Query: 49 LAHTLPVEEPRMEAPPLPLSPPAPPPAPP---------PPLATPAPLTVIP---IPVVTN 96
LA LP+ P APP + P+PP PP PP+ P L IP +P
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 97 SPQPLPPP----------------PPLPAAAQPLPLAPRQ-PALVGAPGLSIKEP---AP 136
SP PP P L A L ++PRQ A + +P P P
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456
Query: 137 LPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTL 196
L + +P PL + P SP + PL + ++A H P + PP T
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA-LSSLASHSPQAPLSSLIMPPLETQ 515
Query: 197 GTL 199
+L
Sbjct: 516 SSL 518
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/165 (28%), Positives = 58/165 (35%), Gaps = 20/165 (12%)
Query: 345 EDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHP-------HPHSVALPPAHL- 396
E+ L PP L P PP P PL P P P S+A PP
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
Query: 397 PVQQQQPQQKTPLP-----APPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASV 451
P P Q P P A PPP A P L P A A + +A + +
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
Query: 452 IQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPA 496
+ H+LQ P PS P A PA+PP+ P+
Sbjct: 656 LAV--HLLQAPFSP-----PPSPPVQAPFSPPASPPVSPSATPPS 693
Score = 48.9 bits (115), Expect = 1e-05
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 352 PPKLSHRPQPELLKSTLP--PPSTTPAPL-PPHPHPHPHSVALP-PAHLPVQQQQPQQKT 407
PP + P P +TLP PP TP PL PP P P LP P P Q P T
Sbjct: 319 PPDNAATPLP----ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374
Query: 408 PLPAPPP-----PP-------AAPAQTLVPAP---AHLVATAGGGSTVIAHTAT------ 446
P PP PP +P+ P+P + L AT GS + T +
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 447 --THASVIQTVNHVLQGPGGKHIAH--IAPSAPSPAVQLAPATPPIGH-ITVHPATLNHV 501
T AS+ P + P++P L+PA P+ +T+HP L +
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP--LQAL 492
Query: 502 AHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGL-GPPATVMAKPAVGAQVVHHPQLVGQ 560
+ L S P P S I L Q L PPA++ P + P L Q
Sbjct: 493 SSLASHSPQAP---LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--Q 547
Query: 561 TVLNPVT 567
T P+T
Sbjct: 548 TASAPLT 554
Score = 47.0 bits (110), Expect = 5e-05
Identities = 114/475 (24%), Positives = 157/475 (33%), Gaps = 69/475 (14%)
Query: 35 EREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVV 94
+ ++++ KA + AR P AP L P P PPPP+ TPA L V+
Sbjct: 2 DNKRDKAKAGAAART--------PAARAPGLLTPRPPGSPRPPPPV-TPAALRVLGAAGA 52
Query: 95 TNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSK 154
+PL A APR A G S + PA SRP P +K
Sbjct: 53 VGR-KPLAERAGGIGGATIPESAPRAGPTRSA-GTSSRNPA---SRPPASGRGERAPPAK 107
Query: 155 ATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKK 214
N SP P+ T P P Q L G AP S+ ++
Sbjct: 108 -----NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162
Query: 215 RPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRK 274
G + + RA E L R P+ + R
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPS--------------------ARPRP 200
Query: 275 EKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASE 334
E + A E T+ A + + R L + P A + ++
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 335 GEDNIDEDMEEDR----AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLP------PHPHP 384
G + + L PP+++ P + L P S++P P P P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
Query: 385 HPHSVALP-PAHLPVQQQQPQQKTPLPAPPPPPAAP--AQTLVPAPAHLVATAGGGSTVI 441
P + A P PA LP P TPLP PP P+AP QTL PA + A T
Sbjct: 319 PPDNAATPLPATLP---PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
Query: 442 AHTATTHASVIQTVN--HVLQGPGGKHIAHIAPSAPSP-AVQLAPATPPIGHITV 493
A I + H L P + PSP A+ AT +G T+
Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPS-------LQAPPSPLALSSLQATTSLGSPTL 423
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 23/153 (15%)
Query: 52 TLPVEEPRMEAPPLPLSPPAPPPAP----PPPLATPAPLTVIPIPVVTNSPQPLPPPPPL 107
T P + P + A PL PP+PP +P P TP P T + P +T + P PPPPP
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
Query: 108 PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ 167
+ + L P L G + P L P + A+ PP+
Sbjct: 886 RSPSSTL----SGPDLAGHSSSATSTPEELRGYDSGPEGG-----AAASPPPDAELAACH 936
Query: 168 PL-----PTPVLTIAPHPGVQPQLAPQQPPPPT 195
P P P L PG AP PP T
Sbjct: 937 PAAWSRGPAPPLAFRGAPG-----APLPWPPAT 964
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/177 (26%), Positives = 65/177 (36%), Gaps = 20/177 (11%)
Query: 347 RAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHL----PVQQQQ 402
+A PP P P + PP S +P P P S+A PP + P
Sbjct: 662 QAPFSPP-----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 403 PQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASV--IQTVNHVLQ 460
TP P PPP AAP + P+P S ++ +AT V + +
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPP--------ASPPMSPSATPPPRVPPLLAAPPLQV 768
Query: 461 GPGGKHIAHIAPSA-PSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVA 516
P ++P A P P A ATPP+ + PA+ A L P+A
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/207 (24%), Positives = 72/207 (34%), Gaps = 28/207 (13%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHP-------HSVALPPAHLPVQQQ 401
G P ++ R + + LP P+ + P PP P HS P P ++
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---PAARR 226
Query: 402 QPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQG 461
+P L P + + T + +PA +A G AH + +Q +
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 462 PGGKHIAH-IAPSAPSP-------AVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQ 513
P K A + P + SP + P PP T PATL L + LPL P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 514 PVAVSHIAHTLSHQQVNGTAGLGPPAT 540
+ TL PPAT
Sbjct: 347 SPSAPPSLQTLP----------SPPAT 363
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/180 (26%), Positives = 63/180 (35%), Gaps = 28/180 (15%)
Query: 356 SHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPP-AHLPVQQQQPQQKT------- 407
SH PQ L +PP T + PP P S+ PP +LP P Q
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556
Query: 408 -----PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGP 462
P PAP P A P+ P P S++ ++ L P
Sbjct: 557 HLETPPCPAPCPLQAPPSPLTTPPPE-------TPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 463 GGKHIAHIAPSAPS----PAVQL---APATPPIGHI-TVHPATLNHVAHLGSQLPLYPQP 514
+A P AP P +Q PA+PP+ + T P N +A Q P P P
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Score = 32.7 bits (73), Expect = 0.94
Identities = 37/148 (25%), Positives = 52/148 (35%), Gaps = 31/148 (20%)
Query: 352 PPKLSHRPQPELLKSTL--PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPL 409
P + P L S L PPP P P P A P P + P T +
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 410 ----------PAPPPPPA-APAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHV 458
P PPPPP+ +P+ TL G + H+++ S + +
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTL------------SGPDLAGHSSSA-TSTPEELRGY 914
Query: 459 LQGPGGKHIAHIAPSAPSPAVQLAPATP 486
GP G A ++P P +LA P
Sbjct: 915 DSGPEGG-----AAASPPPDAELAACHP 937
Score = 32.3 bits (72), Expect = 1.2
Identities = 37/156 (23%), Positives = 45/156 (28%), Gaps = 20/156 (12%)
Query: 352 PPKLSHRP---------QPELLKSTLPPPSTTP---------APLPPHPHPHPHSVALPP 393
PP L+ P P + S PPP P P PP P PP
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 394 AHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQ 453
P P Q P P P AP P +AT + +
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
Query: 454 TVNHVLQGPGGKHI--AHIAPSAPSPAVQLAPATPP 487
+ LQ P + S P + LAP PP
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
Score = 30.4 bits (67), Expect = 4.7
Identities = 51/223 (22%), Positives = 70/223 (31%), Gaps = 28/223 (12%)
Query: 323 EDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHP 382
E + S S+ASE R G RP L S S TP P
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLSS-----SATPLSSPARS 255
Query: 383 HPHPHSVALPPAH-----------LPVQQQQPQQKTPLPAPPPPPAAPAQTLVPA--PAH 429
P PAH L Q P +K PA P ++P T P+ A
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 430 LVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPS-------PAVQLA 482
V +T + T + + P PS P+ P++
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
Query: 483 PATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLS 525
P P T+ P + H + L P P+A+S + T S
Sbjct: 376 PMQAPPSLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATTS 417
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 80.1 bits (196), Expect = 5e-15
Identities = 67/238 (28%), Positives = 95/238 (39%), Gaps = 60/238 (25%)
Query: 15 WQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPV-EEPRMEAPPLPLSPPAP- 72
W+ Q+Q+ EE+E+ + E+E+++E ++ A +P E+ + PP PL+PPAP
Sbjct: 354 WKKQEQKLDDEEEEK-KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS 412
Query: 73 --PPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ----PLPLAP-------- 118
PP PPP + P PL P P V SP PLP PPP PA + P P+ P
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPV--SPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG 470
Query: 119 -----------RQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPN------- 160
R+ A G G S P P + P +P + T N
Sbjct: 471 RPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMP 530
Query: 161 -------------------GSPKP----LQPLPTPVLTIAPHPGVQPQLAPQQPPPPT 195
PKP + P+ P +T +P +P P P PT
Sbjct: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPT 588
Score = 70.9 bits (172), Expect = 3e-12
Identities = 69/234 (29%), Positives = 89/234 (38%), Gaps = 78/234 (33%)
Query: 58 PRMEAPPLPLSP---PAPPPAPPPPLATPAPLTV-------------------IPIPVVT 95
P +PP+P P P+PP AP PP +TP PL +P P
Sbjct: 566 PITTSPPVPQEPAPVPSPPRAPTPP-STPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
Query: 96 NSPQPLPPPPPLPAAAQPLPLAPRQPAL------------------VGAPGLSIKEPAPL 137
P P P PPP PA + PL R P +GAP EP P
Sbjct: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
Query: 138 PSRPQVPTP--------------APLLPDS-KATIPPNGSP-------------KPLQPL 169
P P P AP++ KA + P+G+P +PLQ L
Sbjct: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
Query: 170 PTPVLTIA---PHPGVQPQLAPQQPPP------PTLGTLKLAPAEEVKSSEQKK 214
T +L A P P +QP +PQQ PP +G+L L+ EE S K+
Sbjct: 745 QTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKR 798
Score = 67.0 bits (162), Expect = 5e-11
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 24/194 (12%)
Query: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLA---TPAPLTVIPIPVVTNSPQPLPPPPPLPAAA 111
+ EP L P PPPAPPPP A PAP T P++ +PQ P L
Sbjct: 604 LREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
Query: 112 QPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP--------------APLLPDS-KAT 156
L P +GAP EP P P P P AP++ KA
Sbjct: 664 SVL-----TPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAE 718
Query: 157 IPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
+ P+G+P T + P +Q QL PQ PPP L+ P+ + +K R
Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ-PQLQPPPSPQQMPPLEKARI 777
Query: 217 GGIGTREVHNKLEK 230
G+G+ + EK
Sbjct: 778 AGVGSLPLSGVEEK 791
Score = 58.9 bits (141), Expect = 1e-08
Identities = 74/290 (25%), Positives = 102/290 (35%), Gaps = 39/290 (13%)
Query: 300 KHELSQWMDVLEIDRVLRQTGQP--------EDDQASTSTASEGEDNIDEDMEEDRAGLG 351
+HE S W DV + Q G P DD+ E +D E+ EE
Sbjct: 331 QHEES-WQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEE 389
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPA 411
+ + + +L PPP T PAP PP P P P + PP P P PLP+
Sbjct: 390 MMPAAEKEEAKLP----PPPLTPPAPSPPPPLPPPSTSPPPPLCPP--PPPPVSPPPLPS 443
Query: 412 PPPPPAAPAQTLVP---APAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIA 468
PPPPPA Q P PA G + A A+ GP G
Sbjct: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAA--------RAGPEG---- 491
Query: 469 HIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQ 528
S P+P A PP TV P + + ++ + PV + + + +
Sbjct: 492 ---TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQ----FIMPVVSARSSRVIKTPR 544
Query: 529 VNGTAGLGPPATVMAKPAVGAQVVHHPQLVGQ--TVLNPVTMVTMPSFPV 576
P V P + + P + + V +P T PS PV
Sbjct: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPV 594
Score = 53.1 bits (126), Expect = 7e-07
Identities = 53/149 (35%), Positives = 65/149 (43%), Gaps = 15/149 (10%)
Query: 58 PRMEAPPLPLSPPAPPP--APPPPLATPAPLTVIPIPVVTNSPQPLPPPP--PLPAAAQP 113
P +P L PP P + PPP I +P + S +PL PLP+ P
Sbjct: 1832 PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSP 1891
Query: 114 LPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP-APLLPDSKATIPP-NGSPKPLQPLPT 171
L P VG P PAP P R + P+P AP P S+ PP SP+ P PT
Sbjct: 1892 SSLTHHIPT-VGDPDF----PAP-PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPT 1945
Query: 172 PVLT-IAPHPG--VQPQLAPQQPPPPTLG 197
V+T + P G P AP PPP LG
Sbjct: 1946 SVVTALTPTSGELAPPGPAPSPPPPEDLG 1974
Score = 50.4 bits (119), Expect = 4e-06
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 30/147 (20%)
Query: 99 QPLPPPPPLPAAAQP---LPLAPRQPA-----LVGAPGLSIKEPAPLPSRPQVPTPAPLL 150
+ LPP PPL +QP L +P P L GAPG+ + P P P+ T +L
Sbjct: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIIL 2193
Query: 151 PDSKA-----------TIPPNGSPKPLQPLPTPVL----TIAPHP--GVQPQL-----AP 188
+ +PP PL P +P T+ P P GV P + AP
Sbjct: 2194 VNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAP 2253
Query: 189 QQPPPPTLGTLKLAPAEEVKSSEQKKR 215
PPPP L PA + + + KR
Sbjct: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKR 2280
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLATPAPLT-VIPIPVVTNSPQPLPPPPPLPAAAQPLPL 116
P ++ PPLP P P AP P PL V+P+ V P P PPPPPL P
Sbjct: 2213 PPVKQPPLP--PTISPTAPTSWTLPPGPLLGVLPVVGVVR-PAPPPPPPPLTLVLSSGPA 2269
Query: 117 APRQPAL 123
+P + A+
Sbjct: 2270 SPPRQAI 2276
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/199 (27%), Positives = 78/199 (39%), Gaps = 27/199 (13%)
Query: 45 SLARLAHTLP-VEEPRMEAPPL------PLSPPAPPP---APP----PPLATPAPLTVIP 90
S + L H +P V +P APP PL+P PP +PP P L P P +V
Sbjct: 1890 SPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSV-- 1947
Query: 91 IPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKE----PAPLPSRP-QVPT 145
+ +T + L PP P P+ P L P + GLS + + L + P Q
Sbjct: 1948 VTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEI 2007
Query: 146 PAPLLPDSKATIPPNGSPKPLQPLPTPV---LTIAPHPGVQPQLAPQQPPPPTLGTLKLA 202
A S P + S + P + +T+ PG+ P P P L +
Sbjct: 2008 VAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDG 2067
Query: 203 PAEEVKSSEQKKRPGGIGT 221
E ++ +Q P G GT
Sbjct: 2068 TDSEAEAVQQ---PRGQGT 2083
Score = 39.3 bits (90), Expect = 0.010
Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 32/176 (18%)
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQ----------------- 405
L + PPP P P P P P P + + P L Q P +
Sbjct: 614 LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGA 673
Query: 406 -KTPLPAPPP---PPAAPAQTLVPAPAHL-------VATAGGGSTVIAHTATTHASVIQT 454
+ P P PPP PA P V HL V T + V H A ++ QT
Sbjct: 674 PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQT 733
Query: 455 VNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPL 510
+LQ + + P P QL P P + P +A +GS LPL
Sbjct: 734 QAQLLQPLQALQTQLLPQALPPPQPQLQPPPSP---QQMPPLEKARIAGVGS-LPL 785
Score = 37.0 bits (84), Expect = 0.050
Identities = 26/62 (41%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 368 LPPPSTTPAPLPPHPHPH-PHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPA 426
+PPP P PLPP P P S LPP P+ P PAPPPPP L
Sbjct: 2211 VPPPVKQP-PLPPTISPTAPTSWTLPPG--PLLGVLPVVGVVRPAPPPPPPPLTLVLSSG 2267
Query: 427 PA 428
PA
Sbjct: 2268 PA 2269
Score = 34.3 bits (77), Expect = 0.32
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 10/77 (12%)
Query: 353 PKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAP 412
P + P P P P +TP PLP S+ P + LP P
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLP----EKRRSILREPTF-----RWTSLTRELPPP 621
Query: 413 PP-PPAAPAQTLVPAPA 428
PP PP PA + PAPA
Sbjct: 622 PPAPPPPPAPSPPPAPA 638
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/84 (26%), Positives = 28/84 (33%)
Query: 29 RLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTV 88
R R E+ E+ + L R A R P P PP P V
Sbjct: 179 RKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAV 238
Query: 89 IPIPVVTNSPQPLPPPPPLPAAAQ 112
+ P+P PPPP +P Q
Sbjct: 239 VVAEAAVTIPKPEPPPPVVPVKHQ 262
Score = 30.8 bits (68), Expect = 3.6
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 8/67 (11%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPH---PHPHSVALPPAHLPVQQQQPQQKTP 408
PP+ S RP P L PP PL P P P SV + P P
Sbjct: 1909 PPRRSRRPSP--LAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG---P 1963
Query: 409 LPAPPPP 415
P+PPPP
Sbjct: 1964 APSPPPP 1970
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/148 (37%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVT--NSPQPLPPP-PPLPAA 110
PV+ P P+SP A PP+ PP PL V P P + SP PPP P P A
Sbjct: 447 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 111 AQPLPLAPRQPALVGAPGLSIKEPAPLPSRP-QVPTPAPLLPDSKATIPPNGSPKPLQP- 168
A PL LA +P P L+ LPS P P AP P + + P +P P P
Sbjct: 507 APPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 169 -LPTPVLTIAPHPGVQPQL-APQQPPPP 194
L P+L + P P P L AP++PP P
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTP 592
Score = 72.4 bits (176), Expect = 1e-12
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 26/170 (15%)
Query: 48 RLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLAT-------PAPLTVIPIPVVTNSPQP 100
+LA LP+ P APP + P+PP PP T A + +P P + SP
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL--SPLA 390
Query: 101 LPPP-------------PPLPAAAQPL-PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP 146
PPP PP P A+ PL PLA P A + + + AP P P
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-APFSPPPSPPVQ 449
Query: 147 APLLPDSKATIPPNGSPKPLQP--LPTPVLTIAPHPGVQPQLAPQQPPPP 194
AP P + + P+ +P P L P L + P P P ++P PPP
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
Score = 63.5 bits (153), Expect = 5e-10
Identities = 50/162 (30%), Positives = 65/162 (40%), Gaps = 13/162 (8%)
Query: 62 APPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP-------LPPPPPLPAAAQPL 114
A PLPL+PP+P APP P+P P T+ P P PPL A P
Sbjct: 335 ATPLPLAPPSPS-APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL 174
P AP PAL P + P P + TP+P P++ A + P P P+P +
Sbjct: 394 PQAP--PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV---HLLQAPFSPPPSPPV 448
Query: 175 TIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P P ++P PP AP +V S P
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/149 (34%), Positives = 64/149 (42%), Gaps = 38/149 (25%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQ-PLPPPPPLPAAAQ 112
P P + APPL L+ P PP PP LATP PL +P P + Q P P LP +
Sbjct: 499 PQAPPPLAAPPLQLAKP--PPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 113 PLPLAPRQPALVGAPGLSIKEPAPL------PSRPQVPTPAPLLPDSKATIPPNGSPKPL 166
P P+ P ++ AP L + P P RP PTP PD+ +
Sbjct: 556 ATP-PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPG---PDTSVS---------- 599
Query: 167 QPLPTPVLTIAPHPGVQPQLAPQQPPPPT 195
P LT+A LAP PPPP+
Sbjct: 600 ----GPRLTLA--------LAPGPPPPPS 616
Score = 55.8 bits (133), Expect = 1e-07
Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 29/164 (17%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIP------IPVVTNSPQ-------PLPPP 104
P PP + PA P PLATP+P + +P +S PLP
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341
Query: 105 PPLPAAAQPLPLAPRQPAL--------VGAPGLSIKEP-------APLPSRPQVPTPAPL 149
PP P+A L P PA +G+P L +PL + P PA
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 150 LPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP 193
LP +A P SP PL PL TP V AP PPP
Sbjct: 402 LPPLQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Score = 51.2 bits (121), Expect = 3e-06
Identities = 118/488 (24%), Positives = 158/488 (32%), Gaps = 106/488 (21%)
Query: 73 PPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL---------PLAPRQPAL 123
P A P L TP P P PPPP PAA + L PLA R +
Sbjct: 17 PAARAPGLLTPRP-----------PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 124 VGAPGLSIKEPAPL--PSRP-----QVPTPAPLLPDSKATIPP--NGSPKPLQPLPTPVL 174
GA +I E AP P+R + P P PP N SP P+
Sbjct: 66 GGA---TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 175 TIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRA 234
T P P Q L G AP S+ ++ G + + RA
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 235 HLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQ 294
E L R P+ + + + K E E +
Sbjct: 183 AGTEV--GLPRPAPSARPRPPT---------------EGPRKSVSSASEHSTTEPSPAAR 225
Query: 295 RLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPK 354
R L + R L + P A + ++ G P
Sbjct: 226 RRPSAGGGLQR-----PASRSLSSSATPLSSPARSGPSARGTPRA-------------PA 267
Query: 355 LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHS---VALPPAHLPVQQQQP-------- 403
+P+P+ L++ L PP TP P P S +A P +Q Q P
Sbjct: 268 HPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 404 ------QQKTPLPAPPPPPAAP--AQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTV 455
Q TPLP PP P+AP QTL PA + A T + + +Q
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA---------TTSLGSPTLQAT 377
Query: 456 NHVLQGPGGKHIAHIAPSAPSPAVQL--------APATPPIGHI-TVHPATLNHVAHLGS 506
+ L P +A P AP PA+ L PA+PP+ + T P N +A
Sbjct: 378 HSFLPSPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 507 QLPLYPQP 514
Q P P P
Sbjct: 437 QAPFSPPP 444
Score = 50.4 bits (119), Expect = 4e-06
Identities = 50/158 (31%), Positives = 62/158 (39%), Gaps = 30/158 (18%)
Query: 63 PPLPLSPPAPPP----APPPPLATPAPLTVIP-IPVVTNSPQPLP---------PPPPLP 108
P P P P P A PP TP P + +++SP P PP LP
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 109 AA----------AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIP 158
A A PLPLAP P+ + PA PS+ +P L + + +P
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
Query: 159 PNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPP--PP 194
SP PL PL TP P + P AP PP PP
Sbjct: 383 ---SP-PLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 23/153 (15%)
Query: 52 TLPVEEPRMEAPPLPLSPPAPPPAP----PPPLATPAPLTVIPIPVVTNSPQPLPPPPPL 107
T P + P + A PL PP+PP +P P TP P T + P +T + P PPPPP
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
Query: 108 PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ 167
+ + L P L G + P L P + A+ PP+
Sbjct: 617 RSPSSTL----SGPDLAGHSSSATSTPEELRGYDSGPEGG-----AAASPPPDAELAACH 667
Query: 168 PL-----PTPVLTIAPHPGVQPQLAPQQPPPPT 195
P P P L PG AP PP T
Sbjct: 668 PAAWSRGPAPPLAFRGAPG-----APLPWPPAT 695
Score = 44.3 bits (103), Expect = 3e-04
Identities = 119/569 (20%), Positives = 182/569 (31%), Gaps = 101/569 (17%)
Query: 35 EREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVI----- 89
+ ++++ KA + AR P AP L P P PPPP+ TPA L V+
Sbjct: 2 DNKRDKAKAGAAART--------PAARAPGLLTPRPPGSPRPPPPV-TPAALRVLGAAGA 52
Query: 90 ----------------PIP-----------VVTNSPQPLPPPPPLPAAAQPLPLAPRQPA 122
IP T+S P PP + P P
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112
Query: 123 LVGAPGLS--IKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPK----------PLQPLP 170
V +PG + P PL + + + KAT P S P P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 171 TPVLTIAPHP-GVQ---PQLAPQ-QPPPPTLGTLK-LAPAEEVKSSEQ----KKRP--GG 218
+P + G + P+ AP +P PPT G K ++ A E ++E ++RP GG
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 219 IGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKE--- 275
R L + + R+ P+ + + + +Q+L+ +
Sbjct: 233 GLQRPASRSLSSSATP-----LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 276 --KEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLR-QTGQPEDDQASTSTA 332
K+ + L+ +AT A L+ + + L Q P + +A
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 333 SEGEDNIDEDM----EEDRAGLGPPKL----SHRPQPELLKSTLPPPSTTPA-------- 376
+ + LG P L S P P L PPP PA
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 377 --------PLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAA-PAQTLVPAP 427
PL P P P + HL P P+ AP PPA+ P P
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 428 AHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
+ + + + + + Q P + + P P A ATPP
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Query: 488 IGHITVHPATLNHVAHLGSQLPLYPQPVA 516
+ + PA+ A L P+A
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLA 556
Score = 43.1 bits (100), Expect = 7e-04
Identities = 65/266 (24%), Positives = 86/266 (32%), Gaps = 49/266 (18%)
Query: 347 RAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ---- 402
+A PP P P + PP S +P P P S+A PP +P
Sbjct: 437 QAPFSPP-----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 403 -------PQQKTPLPAPP-----PPPAAPAQTLVPAPAHLVATAGG--GSTVIAHTATTH 448
PQ PL APP PPP AP P L + G + +A+
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 449 ASVIQT----VNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHL 504
S + T VL P + + PS P+ AP PP T P T L
Sbjct: 552 MSPLATPPPQAPPVLAAP----LLQVPPSPPASPTLQAPRRPP----TPGPDTSVSGPRL 603
Query: 505 GSQLPLYPQPVAVSHIAHTLSHQQVNGTAG-------------LGPPATVMAKPAVGAQV 551
L P P + TLS + G + GP A P A++
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663
Query: 552 VH-HPQLVGQTVLNPVTMVTMPSFPV 576
HP + P+ P P+
Sbjct: 664 AACHPAAWSRGPAPPLAFRGAPGAPL 689
Score = 41.2 bits (95), Expect = 0.003
Identities = 59/256 (23%), Positives = 88/256 (34%), Gaps = 30/256 (11%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPH-------PHSVALPPAHLPVQQQ 401
G P ++ R + + LP P+ + P PP P HS P P ++
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---PAARR 226
Query: 402 QPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQG 461
+P L P + + T + +PA +A G AH + +Q +
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 462 PGGKHIA-HIAP------SAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQP 514
P K A + P + PSP+ L PP T H ++L L + LPL P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL--TCQLATPLPLAPPS 344
Query: 515 VAVSHIAHTLSHQQV----NGTAGLGPPA-----TVMAKPAVGAQVVHHPQLVGQTVLNP 565
+ TL T LG P + + P + PQ L P
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 566 VTMVTMP--SFPVSTL 579
+ P S P+S L
Sbjct: 405 LQAPPSPPASPPLSPL 420
Score = 34.7 bits (78), Expect = 0.25
Identities = 61/240 (25%), Positives = 82/240 (34%), Gaps = 17/240 (7%)
Query: 323 EDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHP 382
E + S S+ASE R G RP L S S TP P
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLSS-----SATPLSSPARS 255
Query: 383 HPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIA 442
P PAH + + Q P PP A L P + +AT + + +
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315
Query: 443 HTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQL---APATPPIGHIT-VHPATL 498
T + + + Q +A +PSAP P++Q PATPP T + TL
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 499 NHVAHLGSQLPLYP--QPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKP---AVGAQVVH 553
PL P P + A L Q + PP + +A P A A VH
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/148 (37%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVT--NSPQPLPPP-PPLPAA 110
PV+ P P+SP A PP+ PP PL V P P + SP PPP P P A
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 111 AQPLPLAPRQPALVGAPGLSIKEPAPLPSRP-QVPTPAPLLPDSKATIPPNGSPKPLQP- 168
A PL LA +P P L+ LPS P P AP P + + P +P P P
Sbjct: 468 APPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
Query: 169 -LPTPVLTIAPHPGVQPQL-APQQPPPP 194
L P+L + P P P L AP++PP P
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Score = 73.6 bits (179), Expect = 5e-13
Identities = 60/196 (30%), Positives = 82/196 (41%), Gaps = 33/196 (16%)
Query: 28 ERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPA-----PPPAPPPPLAT 82
+ LR Q + A +L L+ + P+ P APP P +PP+ PPA PP AT
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSS-PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327
Query: 83 --------PAPLTVIPIPVVTNSPQPLPPP-------------PPLPAAAQPL-PLAPRQ 120
A + +P P + SP PPP PP P A+ PL PLA
Sbjct: 328 TSLGSPTLQATHSFLPSPPL--SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 121 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQP--LPTPVLTIAP 178
P A + + + AP P P AP P + + P+ +P P L P L + P
Sbjct: 386 PQAPNALAVHLLQ-APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444
Query: 179 HPGVQPQLAPQQPPPP 194
P P ++P PPP
Sbjct: 445 SPPASPPMSPSATPPP 460
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/149 (34%), Positives = 64/149 (42%), Gaps = 38/149 (25%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQ-PLPPPPPLPAAAQ 112
P P + APPL L+ P PP PP LATP PL +P P + Q P P LP +
Sbjct: 460 PQAPPPLAAPPLQLAKP--PPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 113 PLPLAPRQPALVGAPGLSIKEPAPL------PSRPQVPTPAPLLPDSKATIPPNGSPKPL 166
P P+ P ++ AP L + P P RP PTP PD+ +
Sbjct: 517 ATP-PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPG---PDTSVS---------- 560
Query: 167 QPLPTPVLTIAPHPGVQPQLAPQQPPPPT 195
P LT+A LAP PPPP+
Sbjct: 561 ----GPRLTLA--------LAPGPPPPPS 577
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/153 (32%), Positives = 59/153 (38%), Gaps = 23/153 (15%)
Query: 63 PPLPLSPPAPPP----APPPPLATPAPLTVIP-IPVVTNSPQPLPPP--PPLPAAAQPLP 115
P P P P P A PP TP P + +++SP P P PP P+A L
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 116 LAPRQPAL--------VGAPGLSIKEP-------APLPSRPQVPTPAPLLPDSKATIPPN 160
P PA +G+P L +PL + P PA LP +A P
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373
Query: 161 GSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP 193
SP PL PL TP V AP PPP
Sbjct: 374 ASP-PLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Score = 47.4 bits (111), Expect = 4e-05
Identities = 104/463 (22%), Positives = 143/463 (30%), Gaps = 95/463 (20%)
Query: 73 PPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL---------PLAPRQPAL 123
P A P L TP P P PPPP PAA + L PLA R +
Sbjct: 17 PAARAPGLLTPRP-----------PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 124 VGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQ 183
GA +I E AP + P +A N SP P+ T P P Q
Sbjct: 66 GGA---TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 184 PQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETL 243
L G AP S+ ++ G + + RA E L
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GL 180
Query: 244 KRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHEL 303
R P+ + + + K E E +R L
Sbjct: 181 PRPAPSARPRPPT---------------EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 225
Query: 304 SQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPEL 363
+ R L + P A + ++ G P +P+P+
Sbjct: 226 QR-----PASRSLSSSATPLSSPARSGPSARGTPRA-------------PAHPSQPKPKG 267
Query: 364 LKSTLPPPSTTPAPLPPHPHPHPHS---VALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 420
L++ L PP TP P P S +A P P P LP+PP P + A
Sbjct: 268 LQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326
Query: 421 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ 480
T + +P +Q + L P +A P AP PA+
Sbjct: 327 TTSLGSP-----------------------TLQATHSFLPSPPLSPLATPPPQAP-PALA 362
Query: 481 L--------APATPPIGHI-TVHPATLNHVAHLGSQLPLYPQP 514
L PA+PP+ + T P N +A Q P P P
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 23/153 (15%)
Query: 52 TLPVEEPRMEAPPLPLSPPAPPPAP----PPPLATPAPLTVIPIPVVTNSPQPLPPPPPL 107
T P + P + A PL PP+PP +P P TP P T + P +T + P PPPPP
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 108 PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ 167
+ + L P L G + P L P + A+ PP+
Sbjct: 578 RSPSSTL----SGPDLAGHSSSATSTPEELRGYDSGPEGG-----AAASPPPDAELAACH 628
Query: 168 PL-----PTPVLTIAPHPGVQPQLAPQQPPPPT 195
P P P L PG AP PP T
Sbjct: 629 PAAWSRGPAPPLAFRGAPG-----APLPWPPAT 656
Score = 43.1 bits (100), Expect = 7e-04
Identities = 114/539 (21%), Positives = 174/539 (32%), Gaps = 80/539 (14%)
Query: 35 EREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTV------ 88
+ ++++ KA + AR P AP L P P PPPP+ TPA L V
Sbjct: 2 DNKRDKAKAGAAART--------PAARAPGLLTPRPPGSPRPPPPV-TPAALRVLGAAGA 52
Query: 89 -----------------IPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLS- 130
IP P PP + P P V +PG +
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS 112
Query: 131 -IKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPK----------PLQPLPTPVLTIAPH 179
P PL + + + KAT P S P P+P +
Sbjct: 113 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172
Query: 180 P-GVQ---PQLAPQ-QPPPPTLGTLK-LAPAEEVKSSEQ----KKRP--GGIGTREVHNK 227
G + P+ AP +P PPT G K ++ A E ++E ++RP GG R
Sbjct: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 228 LEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKE-----KEYEHEM 282
L + + R+ P+ + + + +Q+L+ + K+ +
Sbjct: 233 LSSSATP-----LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287
Query: 283 ERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDED 342
L+ +AT A + L P S +T S G +
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLP---------SPPATPPSQATTSLGSPTLQAT 338
Query: 343 MEEDRAGLGPPKLSHRPQ--PELLKSTLPPPSTTPA--PLPPHPHPHPHSVALPPAHLPV 398
+ P + PQ P L L P + PA PL P P P + HL
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398
Query: 399 QQQQPQQKTPLPAPPPPPAA-PAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNH 457
P P+ AP PPA+ P P+ + + + + +
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458
Query: 458 VLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVA 516
Q P + + P P A ATPP+ + PA+ A L P+A
Sbjct: 459 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Score = 43.1 bits (100), Expect = 7e-04
Identities = 65/266 (24%), Positives = 86/266 (32%), Gaps = 49/266 (18%)
Query: 347 RAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ---- 402
+A PP P P + PP S +P P P S+A PP +P
Sbjct: 398 QAPFSPP-----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452
Query: 403 -------PQQKTPLPAPP-----PPPAAPAQTLVPAPAHLVATAGG--GSTVIAHTATTH 448
PQ PL APP PPP AP P L + G + +A+
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 449 ASVIQT----VNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHL 504
S + T VL P + + PS P+ AP PP T P T L
Sbjct: 513 MSPLATPPPQAPPVLAAP----LLQVPPSPPASPTLQAPRRPP----TPGPDTSVSGPRL 564
Query: 505 GSQLPLYPQPVAVSHIAHTLSHQQVNGTAG-------------LGPPATVMAKPAVGAQV 551
L P P + TLS + G + GP A P A++
Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624
Query: 552 VH-HPQLVGQTVLNPVTMVTMPSFPV 576
HP + P+ P P+
Sbjct: 625 AACHPAAWSRGPAPPLAFRGAPGAPL 650
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 78.6 bits (192), Expect = 1e-14
Identities = 67/209 (32%), Positives = 79/209 (37%), Gaps = 41/209 (19%)
Query: 50 AHTLPVEEPRMEAPPLPLSPPAPPPAPPP-----PLATP-----APLTVIPIPVVTNSPQ 99
A T P P + APP P PP PPP PPP P+ TP PLT +PVV
Sbjct: 162 ARTAP-PRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 100 PLPPPPPLPAAAQPLPLAPR--------QPALV-----------------GAPGLSIKEP 134
PPPPP P P PL P +P L G PGL +
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
Query: 135 APLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPP 194
+P + P P P LP + P P P PLP + P + P+ Q PP
Sbjct: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAP--PLPGVNSSSETPPPLPPKSPSFQAPPQ 338
Query: 195 TLGTLKLAPAEEVKSSE---QKKRPGGIG 220
G L S+ QKKR G G
Sbjct: 339 KAGAQALPAPPAPPGSQPFLQKKRHGRPG 367
Score = 75.9 bits (185), Expect = 1e-13
Identities = 58/165 (35%), Positives = 75/165 (45%), Gaps = 38/165 (23%)
Query: 48 RLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLP---PP 104
RL +T APP P P PPP PPPP P PL P P+ ++SP P PP
Sbjct: 151 RLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP---PPPL---PPPLPSSSPIKTPLVSPP 204
Query: 105 PP-----LPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPP 159
P LP A P+P AP P P P P+ P +P PA +L D + P
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPP-----------PPPPPPTPPPLP-PASVLSDK--AVKP 250
Query: 160 NGSPKPLQPLPTPVLTIAP--HPGVQPQLA--------PQQPPPP 194
+P L P+P P+ + P +PG++ + A P PPPP
Sbjct: 251 QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP 295
Score = 69.3 bits (168), Expect = 9e-12
Identities = 56/162 (34%), Positives = 66/162 (40%), Gaps = 23/162 (14%)
Query: 66 PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLP-LAPRQPALV 124
PL PPA P A A T P P V P P PPPPP P PLP +P + LV
Sbjct: 143 PLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPP-PPLPPPLPSSSPIKTPLV 201
Query: 125 GAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQP 184
PG P + P V P P P PP P P P P P ++ V+P
Sbjct: 202 SPPG-----PLTKGNLPVVAPPVPCAP------PPPPPPPPPTPPPLPPASVLSDKAVKP 250
Query: 185 QLAPQQPPP--------PTLG--TLKLAPAEEVKSSEQKKRP 216
QLAP PP P G LK PA + +++ P
Sbjct: 251 QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP 292
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/149 (29%), Positives = 57/149 (38%), Gaps = 18/149 (12%)
Query: 353 PKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALP-PAHLPVQQ----------- 400
P+L + + T PP PAP PP P P P + P P+ P++
Sbjct: 150 PRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTK 209
Query: 401 -QQPQQKTPLP-APPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHV 458
P P+P APPPPP P T P P A+ V A H I +
Sbjct: 210 GNLPVVAPPVPCAPPPPPPPPPPTPPPLPP---ASVLSDKAVKPQLAPLHLPPIPPPLPL 266
Query: 459 LQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
L P G P++P+ Q PA PP
Sbjct: 267 LP-PCGYPGLKAEPASPAQDAQEPPAPPP 294
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/147 (29%), Positives = 52/147 (35%), Gaps = 15/147 (10%)
Query: 79 PLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLP 138
P+ PA + P P P LP PL P +G + P
Sbjct: 107 PVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
Query: 139 SRPQVPTPAPLLPDSKATIPPNGSPKPL---QPLPTPV------LTIAPHPGVQPQL--A 187
RP VP P P P PP P PL P+ TP+ LT P V P + A
Sbjct: 167 PRPNVPAPPPPTPPP----PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA 222
Query: 188 PQQPPPPTLGTLKLAPAEEVKSSEQKK 214
P PPPP T P V S + K
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVK 249
Score = 40.4 bits (93), Expect = 0.005
Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQ------Q 405
PP P +L P P LPP P P P LPP P + +P Q
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP---LLPPCGYPGLKAEPASPAQDAQ 287
Query: 406 KTPLPAPPPPPAAPAQTLVPAPA 428
+ P P PP PP A PA
Sbjct: 288 EPPAPPPPLPPYASCSPRASLPA 310
Score = 39.7 bits (91), Expect = 0.008
Identities = 31/109 (28%), Positives = 39/109 (35%), Gaps = 15/109 (13%)
Query: 65 LPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALV 124
+P+ PP PPP PPPP AP P PPP P + L P
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAP--------------PPPPPSAPPVSTDTSSLRRADPKGR 46
Query: 125 GAPGLSIKEPAPLPSRPQV-PTPAPLLPDSKATIPPNGSPKPLQPLPTP 172
A I++ L Q+ AP + SK T G + TP
Sbjct: 47 SALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTP 95
Score = 38.1 bits (87), Expect = 0.022
Identities = 40/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%)
Query: 342 DMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQ 401
D+ + G GP S P P L T+ P PA P AH +
Sbjct: 116 DVAGGKTGQGPG--SRAPSPRLPNKTISGPLIPPAS--------PRLGNTSEAHGAARTA 165
Query: 402 QPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQG 461
P+ P P PP PP P P P+ +S I+T G
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPS--------------------SSPIKTPLVSPPG 205
Query: 462 PGGKH----IAHIAPSAPSPAVQLAPATPP 487
P K +A P AP P P TPP
Sbjct: 206 PLTKGNLPVVAPPVPCAPPPPPPPPPPTPP 235
Score = 35.0 bits (79), Expect = 0.19
Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 7/34 (20%)
Query: 53 LPVEEPRMEAPPLPLSPPAPP---PAPPPPLATP 83
+PV P PP PL PP PP P PPPP A P
Sbjct: 1 MPVPPP----PPPPLPPPPPPLGAPPPPPPSAPP 30
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 17/89 (19%)
Query: 352 PPKLSHRPQPELLKSTLP---PPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTP 408
PP S P+ L LP S TP PLPP P P Q+ Q
Sbjct: 297 PPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS---------PSFQAPPQKAGAQ---A 344
Query: 409 LPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
LPAPP PP +Q + H AGGG
Sbjct: 345 LPAPPAPPG--SQPFLQKKRHGRPGAGGG 371
Score = 33.1 bits (74), Expect = 0.72
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPPPPLAT 82
P P + PP PL P PPP PP++T
Sbjct: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVST 33
Score = 33.1 bits (74), Expect = 0.72
Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 12/110 (10%)
Query: 375 PAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATA 434
PAP PP P P++ P A LP + PP PP +P+ P A
Sbjct: 290 PAPPPPLP---PYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA------ 340
Query: 435 GGGSTVIAHTATTHAS-VIQTVNHVLQGP-GGKHIAHIAPSAPSPAVQLA 482
G + A A + +Q H G GGK AP A SP +L+
Sbjct: 341 -GAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELS 389
Score = 31.6 bits (70), Expect = 2.1
Identities = 14/27 (51%), Positives = 17/27 (62%), Gaps = 2/27 (7%)
Query: 63 PPLPLSPPAPPP--APPPPLATPAPLT 87
PP P PP PPP APPPP + P++
Sbjct: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVS 32
Score = 30.0 bits (66), Expect = 6.1
Identities = 18/52 (34%), Positives = 20/52 (38%), Gaps = 23/52 (44%)
Query: 368 LPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAP 419
+P P P PLPP P PP P PPPPP+AP
Sbjct: 1 MPVPPPPPPPLPPPP---------PPLGAP--------------PPPPPSAP 29
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 78.6 bits (192), Expect = 1e-14
Identities = 60/176 (34%), Positives = 72/176 (40%), Gaps = 23/176 (13%)
Query: 26 EQERLRLEQEREQEQKKANSLARLAHTLP---VEEPRMEAPPLPLSPPAPPPAPPPPLAT 82
E E+ +Q +E+ S A P V +++APP+P PP PP P PPL
Sbjct: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPP-PAPPLRP 423
Query: 83 PAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQ 142
P P T +P P PPP A P P P L G P + P P P RP
Sbjct: 424 PGPPTGLP-----------PGPPP---GAPPFLRPPGMPGLRG-PLPRLLPPGPPPGRPP 468
Query: 143 VPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQ--PQLAPQQPPPPTL 196
P P P P PP P P P P P P PG+ P + P P PP L
Sbjct: 469 GPPPGP--PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGL 522
Score = 51.2 bits (121), Expect = 3e-06
Identities = 96/407 (23%), Positives = 136/407 (33%), Gaps = 49/407 (12%)
Query: 35 EREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVV 94
E E EQK+A + +E+ PLP P AP L PL P +
Sbjct: 111 EVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNI----LIQDIPLPGAQPPSI 166
Query: 95 TNSPQPLPPPPPLPAAAQPLPL----APRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLL 150
PP A LPL PR P PG P P P PQV
Sbjct: 167 LKKTSAYGPPT---RAVSILPLLGHGVPRLP-----PGRKPPGPPPGPPPPQVVQMYGRK 218
Query: 151 PDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSS 210
+PP + + L +P L H + P + K + + S
Sbjct: 219 VGFALDLPPRRRDEDM--LYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTD-DSD 275
Query: 211 EQKKRPGGIGTREVH-NKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQ 269
K G VH + E++ K ++P KK N+ L +Q
Sbjct: 276 TDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTP----LQ 331
Query: 270 SLKRKEKEYEHEMERLAREKIATQQRLAE--LKHELSQWMDVLEIDRVLRQTGQPEDDQA 327
++ M R+A ++I + R E + + D E ++ ++ + E
Sbjct: 332 AM----------MLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSD 381
Query: 328 STSTASEGEDNIDEDMEEDRAGL----GPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPH 383
TSTAS + + + + GPP L P P L P P LPP P
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLR------PPGPPTGLPPGPP 435
Query: 384 PHPHSVALPPAHLPVQQQQPQQKTPLP---APPPPPAAPAQTLVPAP 427
P PP ++ P+ P P PP PP P L P P
Sbjct: 436 PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP 482
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/116 (31%), Positives = 47/116 (40%), Gaps = 9/116 (7%)
Query: 54 PVEEPRMEAPPLPLSPPAPPP-APPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
P P P P PP PPP PPP L PAP + P P+P PPL
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPP-------PRPGMMRPPLVPPLG 516
Query: 113 PLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQP 168
P P PA + PG+ + P L RP+ + + KAT + P+ P
Sbjct: 517 PAPPGLFPPAPLPNPGV-LSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNP 571
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 77.4 bits (189), Expect = 3e-14
Identities = 70/254 (27%), Positives = 105/254 (41%), Gaps = 62/254 (24%)
Query: 57 EPRMEAPPLPLSP----PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
E R ++P +P P PPP PPPPL + + + + + P P+PPPPP PA A
Sbjct: 305 ENRPQSPATGRTPVFVSPTPPP-PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL 363
Query: 113 PLPLAPRQPA-LVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKA-----TIP----PNGS 162
P P PA L APG + PAP P P + P+P P ++A T+P P G
Sbjct: 364 QAPAVPPPPAPLQIAPG--VLHPAPPPIAPPLVQPSP--PVARAAPVCETVPVHPLPQGE 419
Query: 163 ------PKPLQPLPTP--------VLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV- 207
P P PLP P +T HP P P P + + +P +V
Sbjct: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
Query: 208 KSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRY 267
+SE K+ P +P + D ++ L +R ++
Sbjct: 480 PASEPKRHPS----------------------------TLPVISDARSVLLEAIRKGIQL 511
Query: 268 IQSLKRKEKEYEHE 281
+ +++E+E +HE
Sbjct: 512 RKVEEQREQEAKHE 525
Score = 46.2 bits (108), Expect = 8e-05
Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 39/203 (19%)
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQT 422
L+++ P+T P+ P P P LP A + TP P PPPP PA
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATA 362
Query: 423 L----VPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPA 478
L VP P + A G V H P IAP P+
Sbjct: 363 LQAPAVPPPPAPLQIAPG------------------VLHPAPPP-------IAPPLVQPS 397
Query: 479 VQLAPATPPIGHITVHPATLNHVAHLGSQLPLYP---------QPVAVSHIAHTLSHQQV 529
+A A P + VHP V L P P PV V+ +AH S
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
Query: 530 NGTAGLGPPATVMAKPAVGAQVV 552
+ GP +M P+ +QV+
Sbjct: 458 TPSTAPGPHVPLM-PPSPPSQVI 479
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 41/186 (22%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSV---ALPPAHLPVQ-------QQ 401
PP L L++++ ST P P+PP P P ++ A+PP P+Q
Sbjct: 328 PPPLPSALSTSSLRASMT--STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385
Query: 402 QPQQKTPL--PAPPPPPAAPAQTLVPA----------------PAHLVATAGGGSTVIAH 443
P PL P+PP AAP VP P L S+ +
Sbjct: 386 PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTV 445
Query: 444 TATTH-ASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVA 502
TA H S + GP H+ PSP Q+ PA+ P HP+TL ++
Sbjct: 446 TALAHPPSGLHPTPSTAPGP------HVPLMPPSPPSQVIPASEP----KRHPSTLPVIS 495
Query: 503 HLGSQL 508
S L
Sbjct: 496 DARSVL 501
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 34/167 (20%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPP-PPPA 417
P P L ++ S T P PP P P P PPA T L AP PPP
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPP-----PPA------------TALQAPAVPPPP 372
Query: 418 APAQ----TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPS 473
AP Q L PAP + S +A A +V V+ + QG + + P
Sbjct: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV--PVHPLPQG----EVQGLPPP 426
Query: 474 APSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHI 520
P P + PP G P T+ +AH S L P H+
Sbjct: 427 PPPPPL------PPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
Score = 37.0 bits (84), Expect = 0.050
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 15/112 (13%)
Query: 47 ARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
A + T+PV P+ E LP PPP PP P P + + + + + P L P P
Sbjct: 404 APVCETVPVHPLPQGEVQGLP----PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 106 PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATI 157
A +PL P P P I PA P R P+ P++ D+++ +
Sbjct: 460 S-TAPGPHVPLMPPSP-----PSQVI--PASEPKRH--PSTLPVISDARSVL 501
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 77.4 bits (189), Expect = 3e-14
Identities = 70/254 (27%), Positives = 105/254 (41%), Gaps = 62/254 (24%)
Query: 57 EPRMEAPPLPLSP----PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
E R ++P +P P PPP PPPPL + + + + + P P+PPPPP PA A
Sbjct: 305 ENRPQSPATGRTPVFVSPTPPP-PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL 363
Query: 113 PLPLAPRQPA-LVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKA-----TIP----PNGS 162
P P PA L APG + PAP P P + P+P P ++A T+P P G
Sbjct: 364 QAPAVPPPPAPLQIAPG--VLHPAPPPIAPPLVQPSP--PVARAAPVCETVPVHPLPQGE 419
Query: 163 ------PKPLQPLPTP--------VLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV- 207
P P PLP P +T HP P P P + + +P +V
Sbjct: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
Query: 208 KSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRY 267
+SE K+ P +P + D ++ L +R ++
Sbjct: 480 PASEPKRHPS----------------------------TLPVISDARSVLLEAIRKGIQL 511
Query: 268 IQSLKRKEKEYEHE 281
+ +++E+E +HE
Sbjct: 512 RKVEEQREQEAKHE 525
Score = 46.2 bits (108), Expect = 8e-05
Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 39/203 (19%)
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQT 422
L+++ P+T P+ P P P LP A + TP P PPPP PA
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATA 362
Query: 423 L----VPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPA 478
L VP P + A G V H P IAP P+
Sbjct: 363 LQAPAVPPPPAPLQIAPG------------------VLHPAPPP-------IAPPLVQPS 397
Query: 479 VQLAPATPPIGHITVHPATLNHVAHLGSQLPLYP---------QPVAVSHIAHTLSHQQV 529
+A A P + VHP V L P P PV V+ +AH S
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
Query: 530 NGTAGLGPPATVMAKPAVGAQVV 552
+ GP +M P+ +QV+
Sbjct: 458 TPSTAPGPHVPLM-PPSPPSQVI 479
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 41/186 (22%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSV---ALPPAHLPVQ-------QQ 401
PP L L++++ ST P P+PP P P ++ A+PP P+Q
Sbjct: 328 PPPLPSALSTSSLRASMT--STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385
Query: 402 QPQQKTPL--PAPPPPPAAPAQTLVPA----------------PAHLVATAGGGSTVIAH 443
P PL P+PP AAP VP P L S+ +
Sbjct: 386 PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTV 445
Query: 444 TATTH-ASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVA 502
TA H S + GP H+ PSP Q+ PA+ P HP+TL ++
Sbjct: 446 TALAHPPSGLHPTPSTAPGP------HVPLMPPSPPSQVIPASEP----KRHPSTLPVIS 495
Query: 503 HLGSQL 508
S L
Sbjct: 496 DARSVL 501
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 34/167 (20%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPP-PPPA 417
P P L ++ S T P PP P P P PPA T L AP PPP
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPP-----PPA------------TALQAPAVPPPP 372
Query: 418 APAQ----TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPS 473
AP Q L PAP + S +A A +V V+ + QG + + P
Sbjct: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV--PVHPLPQG----EVQGLPPP 426
Query: 474 APSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHI 520
P P + PP G P T+ +AH S L P H+
Sbjct: 427 PPPPPL------PPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
Score = 37.0 bits (84), Expect = 0.050
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 15/112 (13%)
Query: 47 ARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
A + T+PV P+ E LP PPP PP P P + + + + + P L P P
Sbjct: 404 APVCETVPVHPLPQGEVQGLP----PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 106 PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATI 157
A +PL P P P I PA P R P+ P++ D+++ +
Sbjct: 460 S-TAPGPHVPLMPPSP-----PSQVI--PASEPKRH--PSTLPVISDARSVL 501
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 77.4 bits (189), Expect = 3e-14
Identities = 70/254 (27%), Positives = 105/254 (41%), Gaps = 62/254 (24%)
Query: 57 EPRMEAPPLPLSP----PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
E R ++P +P P PPP PPPPL + + + + + P P+PPPPP PA A
Sbjct: 305 ENRPQSPATGRTPVFVSPTPPP-PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL 363
Query: 113 PLPLAPRQPA-LVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKA-----TIP----PNGS 162
P P PA L APG + PAP P P + P+P P ++A T+P P G
Sbjct: 364 QAPAVPPPPAPLQIAPG--VLHPAPPPIAPPLVQPSP--PVARAAPVCETVPVHPLPQGE 419
Query: 163 ------PKPLQPLPTP--------VLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV- 207
P P PLP P +T HP P P P + + +P +V
Sbjct: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
Query: 208 KSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRY 267
+SE K+ P +P + D ++ L +R ++
Sbjct: 480 PASEPKRHPS----------------------------TLPVISDARSVLLEAIRKGIQL 511
Query: 268 IQSLKRKEKEYEHE 281
+ +++E+E +HE
Sbjct: 512 RKVEEQREQEAKHE 525
Score = 46.2 bits (108), Expect = 8e-05
Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 39/203 (19%)
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQT 422
L+++ P+T P+ P P P LP A + TP P PPPP PA
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATA 362
Query: 423 L----VPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPA 478
L VP P + A G V H P IAP P+
Sbjct: 363 LQAPAVPPPPAPLQIAPG------------------VLHPAPPP-------IAPPLVQPS 397
Query: 479 VQLAPATPPIGHITVHPATLNHVAHLGSQLPLYP---------QPVAVSHIAHTLSHQQV 529
+A A P + VHP V L P P PV V+ +AH S
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
Query: 530 NGTAGLGPPATVMAKPAVGAQVV 552
+ GP +M P+ +QV+
Sbjct: 458 TPSTAPGPHVPLM-PPSPPSQVI 479
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 41/186 (22%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSV---ALPPAHLPVQ-------QQ 401
PP L L++++ ST P P+PP P P ++ A+PP P+Q
Sbjct: 328 PPPLPSALSTSSLRASMT--STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385
Query: 402 QPQQKTPL--PAPPPPPAAPAQTLVPA----------------PAHLVATAGGGSTVIAH 443
P PL P+PP AAP VP P L S+ +
Sbjct: 386 PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTV 445
Query: 444 TATTH-ASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVA 502
TA H S + GP H+ PSP Q+ PA+ P HP+TL ++
Sbjct: 446 TALAHPPSGLHPTPSTAPGP------HVPLMPPSPPSQVIPASEP----KRHPSTLPVIS 495
Query: 503 HLGSQL 508
S L
Sbjct: 496 DARSVL 501
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 34/167 (20%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPP-PPPA 417
P P L ++ S T P PP P P P PPA T L AP PPP
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPP-----PPA------------TALQAPAVPPPP 372
Query: 418 APAQ----TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPS 473
AP Q L PAP + S +A A +V V+ + QG + + P
Sbjct: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV--PVHPLPQG----EVQGLPPP 426
Query: 474 APSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHI 520
P P + PP G P T+ +AH S L P H+
Sbjct: 427 PPPPPL------PPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
Score = 37.0 bits (84), Expect = 0.050
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 15/112 (13%)
Query: 47 ARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
A + T+PV P+ E LP PPP PP P P + + + + + P L P P
Sbjct: 404 APVCETVPVHPLPQGEVQGLP----PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 106 PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATI 157
A +PL P P P I PA P R P+ P++ D+++ +
Sbjct: 460 S-TAPGPHVPLMPPSP-----PSQVI--PASEPKRH--PSTLPVISDARSVL 501
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 77.4 bits (189), Expect = 3e-14
Identities = 70/254 (27%), Positives = 105/254 (41%), Gaps = 62/254 (24%)
Query: 57 EPRMEAPPLPLSP----PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQ 112
E R ++P +P P PPP PPPPL + + + + + P P+PPPPP PA A
Sbjct: 305 ENRPQSPATGRTPVFVSPTPPP-PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL 363
Query: 113 PLPLAPRQPA-LVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKA-----TIP----PNGS 162
P P PA L APG + PAP P P + P+P P ++A T+P P G
Sbjct: 364 QAPAVPPPPAPLQIAPG--VLHPAPPPIAPPLVQPSP--PVARAAPVCETVPVHPLPQGE 419
Query: 163 ------PKPLQPLPTP--------VLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV- 207
P P PLP P +T HP P P P + + +P +V
Sbjct: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
Query: 208 KSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRY 267
+SE K+ P +P + D ++ L +R ++
Sbjct: 480 PASEPKRHPS----------------------------TLPVISDARSVLLEAIRKGIQL 511
Query: 268 IQSLKRKEKEYEHE 281
+ +++E+E +HE
Sbjct: 512 RKVEEQREQEAKHE 525
Score = 46.2 bits (108), Expect = 8e-05
Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 39/203 (19%)
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQT 422
L+++ P+T P+ P P P LP A + TP P PPPP PA
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATA 362
Query: 423 L----VPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPA 478
L VP P + A G V H P IAP P+
Sbjct: 363 LQAPAVPPPPAPLQIAPG------------------VLHPAPPP-------IAPPLVQPS 397
Query: 479 VQLAPATPPIGHITVHPATLNHVAHLGSQLPLYP---------QPVAVSHIAHTLSHQQV 529
+A A P + VHP V L P P PV V+ +AH S
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
Query: 530 NGTAGLGPPATVMAKPAVGAQVV 552
+ GP +M P+ +QV+
Sbjct: 458 TPSTAPGPHVPLM-PPSPPSQVI 479
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 41/186 (22%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSV---ALPPAHLPVQ-------QQ 401
PP L L++++ ST P P+PP P P ++ A+PP P+Q
Sbjct: 328 PPPLPSALSTSSLRASMT--STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385
Query: 402 QPQQKTPL--PAPPPPPAAPAQTLVPA----------------PAHLVATAGGGSTVIAH 443
P PL P+PP AAP VP P L S+ +
Sbjct: 386 PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTV 445
Query: 444 TATTH-ASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVA 502
TA H S + GP H+ PSP Q+ PA+ P HP+TL ++
Sbjct: 446 TALAHPPSGLHPTPSTAPGP------HVPLMPPSPPSQVIPASEP----KRHPSTLPVIS 495
Query: 503 HLGSQL 508
S L
Sbjct: 496 DARSVL 501
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 34/167 (20%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPP-PPPA 417
P P L ++ S T P PP P P P PPA T L AP PPP
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPP-----PPA------------TALQAPAVPPPP 372
Query: 418 APAQ----TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPS 473
AP Q L PAP + S +A A +V V+ + QG + + P
Sbjct: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV--PVHPLPQG----EVQGLPPP 426
Query: 474 APSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHI 520
P P + PP G P T+ +AH S L P H+
Sbjct: 427 PPPPPL------PPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
Score = 37.0 bits (84), Expect = 0.050
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 15/112 (13%)
Query: 47 ARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPP 105
A + T+PV P+ E LP PPP PP P P + + + + + P L P P
Sbjct: 404 APVCETVPVHPLPQGEVQGLP----PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 106 PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATI 157
A +PL P P P I PA P R P+ P++ D+++ +
Sbjct: 460 S-TAPGPHVPLMPPSP-----PSQVI--PASEPKRH--PSTLPVISDARSVL 501
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 76.6 bits (187), Expect = 6e-14
Identities = 57/194 (29%), Positives = 79/194 (40%), Gaps = 23/194 (11%)
Query: 42 KANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPL 101
K +S+ +H P P + +PP P APPPAPPPP P P+ IP
Sbjct: 290 KRSSVVSPSHPPPA--PPLGSPPGPKPGFAPPPAPPPP---PPPMIGIP----------- 333
Query: 102 PPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT--PAPLLPDSKATIPP 159
PPPPP+ + P P P+ P + P P P PT P PL + PP
Sbjct: 334 PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393
Query: 160 NGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGI 219
P P P P P P + P L+ P +L + A ++ + + Q G
Sbjct: 394 PPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQ-----GF 448
Query: 220 GTREVHNKLEKNRR 233
R V + E+ +R
Sbjct: 449 QLRRVEEQREQEKR 462
Score = 55.5 bits (132), Expect = 1e-07
Identities = 73/309 (23%), Positives = 107/309 (34%), Gaps = 77/309 (24%)
Query: 24 REEQERLRLEQEREQEQKKANSLA----------RLAHTLPVEEPRMEAPPLPLSPPAPP 73
+EE E++++ QE + ++K + + V+ PP S +P
Sbjct: 200 KEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPS 259
Query: 74 PA------PPPP--------------LATPAPLTVIPIPVVTNSPQPLPP----PPPLPA 109
P+ PPPP LA P +V+ + P P PP P P P
Sbjct: 260 PSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVS----PSHPPPAPPLGSPPGPKPG 315
Query: 110 AAQPLPLAPRQPALVGAPGLSIKEPAPL----PSRPQVPTPAPLLPDSKATIPPNGSPKP 165
A P P P ++G P P P+ P P P+P P PP P P
Sbjct: 316 FAPPPAPPPPPPPMIGIP----PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPP 371
Query: 166 LQPLPTPVLTIAPHPGVQPQ--LAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTRE 223
P T+ P P QP P PPPP G G G
Sbjct: 372 AADYP----TLPPPPLSQPTGGAPPPPPPPPPPG------------PPPPPFTGADGQPA 415
Query: 224 VHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEME 283
+ L + K ++P V D ++ LS +R + L+R E++ E E
Sbjct: 416 IPPPLSDTTKP---------KSSLPAVSDARSDLLSAIRQGFQ----LRRVEEQREQEKR 462
Query: 284 RLAREKIAT 292
+ +AT
Sbjct: 463 DVVGNDVAT 471
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/227 (26%), Positives = 84/227 (37%), Gaps = 46/227 (20%)
Query: 230 KNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREK 289
K +R H KE K++ PN + N ++T + +K ++ E ++EK
Sbjct: 173 KEKRKHRKE-----KKDNPN---RGNVNPRKIKTRKEEWEKMKMGQEFVE------SKEK 218
Query: 290 IATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDR-- 347
+ T L ++ V +D P+ D AS+ + S EDN+ E
Sbjct: 219 LGTSGYPPTLVYQNGSIGCVENVD-ASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYP 277
Query: 348 ------AGLGPPKLSH-------RPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPA 394
+GL PK S P P L P P P P P P P P + +PP
Sbjct: 278 VDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAP--PPPPPPMIGIPPP 335
Query: 395 HLPVQQQQPQQKTP--------------LPAPPPPPAAPAQTLVPAP 427
PV P P P PPPPPAA TL P P
Sbjct: 336 PPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP 382
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/90 (33%), Positives = 33/90 (36%), Gaps = 17/90 (18%)
Query: 347 RAGLGPPKLSHRPQPELLKSTLPPP-------STTPAPLPPHPHPHPHSVALPPAHLPVQ 399
+ G PP P P ++ PPP T P P PP PHP A PP P
Sbjct: 313 KPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372
Query: 400 Q----------QQPQQKTPLPAPPPPPAAP 419
QP P P PPPPP P
Sbjct: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402
Score = 30.0 bits (66), Expect = 6.1
Identities = 23/72 (31%), Positives = 25/72 (34%), Gaps = 24/72 (33%)
Query: 359 PQPELLKSTLPPPSTT-PAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPP- 416
P P TLPPP + P P P P P P P PPPPP
Sbjct: 369 PPPAADYPTLPPPPLSQPTGGAPPPPPPP---------------------PPPGPPPPPF 407
Query: 417 -AAPAQTLVPAP 427
A Q +P P
Sbjct: 408 TGADGQPAIPPP 419
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 75.5 bits (184), Expect = 1e-13
Identities = 66/201 (32%), Positives = 81/201 (40%), Gaps = 25/201 (12%)
Query: 13 LEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHT-----LPVEEPRMEAPPLPL 67
L W A Q Q + + E + E +++ + LP E P L +
Sbjct: 816 LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGM 875
Query: 68 SPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPP-LPAAAQPLPLAPRQPALVGA 126
PP PPP P + T P T IP P + LPPPPP LP A P P P L GA
Sbjct: 876 VPPPPPPLPGMTVPT-LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP-----PPLPGA 929
Query: 127 --------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPP--NGSPKPLQPLPTPVLTI 176
PG I P PLP +P P P LP + +PP G+ P P P P I
Sbjct: 930 GILPLPPLPGAGIPPPPPLPG-AAIPPPPP-LPGAGIPLPPPLPGAGIP-PPPPLPGAGI 986
Query: 177 APHPGVQPQLAPQQPPPPTLG 197
P P + P PP P G
Sbjct: 987 PPPPPLPGAGIPPPPPLPGAG 1007
Score = 74.3 bits (181), Expect = 3e-13
Identities = 62/174 (35%), Positives = 70/174 (40%), Gaps = 26/174 (14%)
Query: 63 PPLP-LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP-LPPPPPLPAAAQPLPLA--- 117
PPLP P PPP P + P PL + IP P +PPPPPLP A P P
Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181
Query: 118 ---PRQPALVGA--------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPL 166
P P L G PG I P PLP P PAP LP IP P PL
Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP----PPPL 1237
Query: 167 QPLPTPVLTIAPHPGVQ----PQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P+ P L P G PQ+ PPP G L ++ S +Q P
Sbjct: 1238 LPVSGPPL--LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEP 1289
Score = 70.1 bits (170), Expect = 5e-12
Identities = 61/158 (38%), Positives = 68/158 (43%), Gaps = 31/158 (19%)
Query: 63 PPLP-LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP-QPLPPPPPLPAAAQPLPLAPRQ 120
PPLP P PPP P + P PL + IP P +PPPPPLP A P P
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP----- 1132
Query: 121 PALVGAPGLSIKEPAPLPSRPQVPTPAPL--------LPDSKATIPPNGSPKPL------ 166
P L PG I P PLP R +P P PL P A IPP P PL
Sbjct: 1133 PPL---PGAGIPPPPPLP-RVGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPLPGVGIP 1185
Query: 167 QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPA 204
P P P + I P P P PPPP L + + PA
Sbjct: 1186 PPPPLPGVGIPPPP---PLPGAGIPPPPPLPGMGIPPA 1220
Score = 68.9 bits (167), Expect = 1e-11
Identities = 58/151 (38%), Positives = 64/151 (42%), Gaps = 28/151 (18%)
Query: 63 PPLP-LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP-QPLPPPPPLPAAAQPLPLAPRQ 120
PPLP P PPP P + P PL IP P +PPPPPLP A P P
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----- 1088
Query: 121 PALVGA--------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPL------ 166
P L GA PG+ I P PLP +P P PL A IPP P PL
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPL---PGAGIPP---PPPLPGAGIP 1141
Query: 167 QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLG 197
P P P + I P P + P PP P G
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG 1172
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/173 (37%), Positives = 70/173 (40%), Gaps = 38/173 (21%)
Query: 53 LPVEEPRMEAPPLPLSPPA--PPPAPPPPLATPAPLTVIPIPVVTNSPQP------LPPP 104
LP P PP P P A PPP P P P P P+P P P +PPP
Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPP 1022
Query: 105 PPLPAAA----QPLPLA--PRQPALVGA--------PGLSIKEPAPLPSRPQVPTPAPLL 150
PPLP A PLP A P P L GA PG I P PLP +P P PL
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPL- 1080
Query: 151 PDSKATIPPNGSPKPL------QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLG 197
A IPP P PL P P P + I P P + P PP P G
Sbjct: 1081 --PGAGIPP---PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/177 (36%), Positives = 69/177 (38%), Gaps = 29/177 (16%)
Query: 63 PPLP-LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP-LPPPPPLPAAA----QPLPL 116
PPLP P PPP P + P PL IP P +PPPPPLP A PLP
Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Query: 117 A--PRQPALVGA--------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPL 166
A P P L GA PG I P PLP +P P PL A IPP P PL
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL---PGAGIPP---PPPL 1102
Query: 167 Q------PLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPG 217
P P P I P P + P PP P G P V PG
Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG 1159
Score = 68.2 bits (165), Expect = 2e-11
Identities = 61/157 (38%), Positives = 66/157 (42%), Gaps = 29/157 (18%)
Query: 63 PPLP-LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP-QPLPPPPPLPAAA----QPLPL 116
PPLP + P PPP P + P PL IP P +PPPPPLP A PLP
Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1005
Query: 117 A--PRQPALVGA--------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPL 166
A P P L GA PG I P PLP +P P PL A IPP P PL
Sbjct: 1006 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPL---PGAGIPP---PPPL 1058
Query: 167 ------QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLG 197
P P P I P P + P PP P G
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
Score = 67.0 bits (162), Expect = 5e-11
Identities = 59/165 (35%), Positives = 66/165 (40%), Gaps = 40/165 (24%)
Query: 58 PRMEAPPLPLSPPAP-----PPAPPPPLATPAPLTVIPIPVVTNSPQP------LPPPPP 106
P + +PL PP P PP P P P P P+P P P +PPPPP
Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP 1013
Query: 107 LPAAAQPLPLAPRQPALVGA--------PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIP 158
LP A P P P L GA PG I P PLP +P P PL A IP
Sbjct: 1014 LPGAGIPPP-----PPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPL---PGAGIP 1064
Query: 159 PNGSPKPL------QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLG 197
P P PL P P P I P P + P PP P +G
Sbjct: 1065 P---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106
Score = 50.4 bits (119), Expect = 4e-06
Identities = 67/217 (30%), Positives = 84/217 (38%), Gaps = 45/217 (20%)
Query: 28 ERLRLEQEREQEQKKANSLARLAHTLPVEEPR-MEAPP---LPLSPPAPPPA---PPPPL 80
E LRLE++ + + A+ T P EE + PP LP PP PP A P
Sbjct: 724 EALRLEEKEVRHHRILE--AKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKF 781
Query: 81 ATPAPLTVIP--IPVVTNSPQPL-----PPPPP--LPAAAQPLPLAPRQPALVGAP---- 127
+ L V P I V +S QP PPPPP L +A Q P + P +
Sbjct: 782 CSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQP-GSQPPHSISTEFQTS 840
Query: 128 -----------GLSIKEPAPLP------SRP---QVPTPAPLLPD-SKATIPPNGSPKPL 166
+I P PLP S P VP P P LP + T+P P+P
Sbjct: 841 HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP- 899
Query: 167 QPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAP 203
PL + P P + P PP P G L L P
Sbjct: 900 PPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 348 AGLGPP----KLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP ++ P P L + +PPP P P P P P PP LP P
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P PPPP P + PAPA + G G
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG 1231
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/165 (28%), Positives = 62/165 (37%), Gaps = 39/165 (23%)
Query: 54 PVEEPRMEAPPLPLSP----PAPPPAPPPPLATPAPLTVI------PIPVVTNSPQP--- 100
P PR+ PP P P P PPP P + P PL + P+P V P P
Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP 1202
Query: 101 ---LPPPPPLP--------AAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPL 149
+PPPPPLP A PL P + P L + P P PQV +
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAP----PLPPPGTGIPPPPLLPVSGP---PLLPQVGSSTLP 1255
Query: 150 LPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPP 194
P +PP PLP+ + + + + P +P P
Sbjct: 1256 TPQVCGFLPP--------PLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
Score = 43.9 bits (102), Expect = 4e-04
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP + P P L + +PPP P P P P P + PP LP P
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPP 1177
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPP 1056
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 984 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPP 1067
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 995 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPP 1078
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1006 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPP 1089
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPP 1100
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Query: 352 PPKLSHRPQPELLKSTLP--PPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPL 409
PP L P L + +P PP LPP P P P + PP LP P P
Sbjct: 880 PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPG 939
Query: 410 PAPPPPPAAPAQTLVPAP 427
PPPP P + P P
Sbjct: 940 AGIPPPPPLPGAAIPPPP 957
Score = 43.1 bits (100), Expect = 7e-04
Identities = 24/69 (34%), Positives = 28/69 (40%)
Query: 359 PQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAA 418
P P L + +PPP P P P P P + PP LP P P PPPP
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 419 PAQTLVPAP 427
P + P P
Sbjct: 1004 PGAGIPPPP 1012
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPP 1111
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1098
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPP 1122
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPP 1133
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P PP LP P
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPP 1144
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1132 PPPLPGAGIPPPPPLPRVGIPPPP 1155
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L + +PPP P P P P P + PP LP P
Sbjct: 1116 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAP 427
P PPPP P + P P
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPP 1199
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/78 (41%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 359 PQPELLKST--LPPPSTTPAPLP----PHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAP 412
PQP L+ T LPPP P PLP P P P P + LP LP P P A
Sbjct: 897 PQPPPLQGTEMLPPP---PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI 953
Query: 413 PPPPAAPAQTLVPAPAHL 430
PPPP P +P P L
Sbjct: 954 PPPPPLPGAG-IPLPPPL 970
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/85 (34%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHS-VALPPAHLPVQQQQ 402
AG+ PP P P L + +PPP P P P P P + + LPP LP
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP-LPGAGIP 976
Query: 403 PQQKTPLPAPPPPPAAPAQTLVPAP 427
P P PPPP P + P P
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPP 1001
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/67 (34%), Positives = 27/67 (40%)
Query: 361 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 420
P L + +PPP P P P P P + PP LP P P PPPP P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 421 QTLVPAP 427
+ P P
Sbjct: 1028 AGIPPPP 1034
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/97 (31%), Positives = 37/97 (38%), Gaps = 6/97 (6%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQP 403
AG+ PP P P L +PPP P P P P P + PP LP P
Sbjct: 1160 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219
Query: 404 QQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTV 440
PLP PP P L+P + G ST+
Sbjct: 1220 APAPPLP--PPGTGIPPPPLLPVSGPPLLPQVGSSTL 1254
Score = 37.7 bits (86), Expect = 0.029
Identities = 50/208 (24%), Positives = 72/208 (34%), Gaps = 42/208 (20%)
Query: 367 TLPPPSTTPA--PLPPHPHPHPH-------SVALPPAHLPVQQQQPQQKTPLPAPPPPPA 417
TLPP P P PP P S+ + P + VQ Q + PPPPP+
Sbjct: 756 TLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPS 815
Query: 418 APAQTLVPAPAHLVATAGGG--STVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAP 475
L+ +AG G + H+ +T QT + K+ +I P
Sbjct: 816 ------------LLWSAGQGQPGSQPPHSISTE---FQTSHEHSVSSAFKNSCNIPSPPP 860
Query: 476 SPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGL 535
P + + + P +G + P L + PQP + GT L
Sbjct: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP------------PPLQGTEML 908
Query: 536 GPPATVMAKPAVGAQVVHHPQLVGQTVL 563
PP P GA + P L G +L
Sbjct: 909 PPP----PPPLPGAGIPPPPPLPGAGIL 932
Score = 35.4 bits (80), Expect = 0.15
Identities = 55/220 (25%), Positives = 84/220 (38%), Gaps = 49/220 (22%)
Query: 16 QAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSP------ 69
QA + Q+ +++Q +L+L+Q+++Q+Q + EEP APP +SP
Sbjct: 201 QAIRLQQQQQQQLQLQLQQQQQQQQLQG-----------AEEP--AAPPTAVSPQPGAFL 247
Query: 70 ------------PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPP--LPAAAQP-L 114
P P + L+ +P + +P PP P LP + P L
Sbjct: 248 GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL 307
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLL---------PDSKATIPPNGSPKP 165
P A QPA +P S P P + AP+ + P GSP
Sbjct: 308 PAA--QPAAKDSPS-STAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPG- 363
Query: 166 LQPLPTPVLTIAPHP-GVQPQLAPQQPPPPTLGTLKLAPA 204
+ V AP G +P+ Q P P +L +PA
Sbjct: 364 -EEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPA 402
Score = 35.0 bits (79), Expect = 0.19
Identities = 30/110 (27%), Positives = 38/110 (34%), Gaps = 8/110 (7%)
Query: 318 QTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAP 377
Q G ST + E ++ + PP L +S+ P P
Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP------CTESSSSMPGLGMVP 877
Query: 378 LPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAP 427
PP P P LP +P Q P Q T + PPPPP A P P
Sbjct: 878 PPPPPLPGMTVPTLPSTAIP--QPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
Score = 33.1 bits (74), Expect = 0.72
Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 11/89 (12%)
Query: 348 AGLGPPK----LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ- 402
AG+ PP + P P L +PPP P P P P P + +PPA P
Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP-GMGIPPAPAPPLPPPG 1229
Query: 403 ----PQQKTPLPAPPPPPAAPAQTLVPAP 427
P P+ PP P + TL P P
Sbjct: 1230 TGIPPPPLLPVSGPPLLPQVGSSTL-PTP 1257
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/156 (36%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 54 PVEEPRMEAPPLPLSPPAPPPAPP--PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA- 110
P E P PP P PP PPPAPP PPL + A IP P +P P P A
Sbjct: 20 PAESPE---PPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATE 76
Query: 111 --AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKP-LQ 167
+P P +PA AP EPAP P+ P PA P+ P +P+P L+
Sbjct: 77 LYTEPTPEPATEPASEPAPE-PATEPAPEPATEPAPEPA---PEPATESAPEPTPEPALE 132
Query: 168 PLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAP 203
+P P + P V P+LAP+ P P +LAP
Sbjct: 133 SVPEPAPELTPE--VAPELAPEPTPEP---VTELAP 163
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 20/141 (14%)
Query: 52 TLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAA 111
T P EP E P PA PAP P P P ++P+P P P L +
Sbjct: 87 TEPASEPAPEPATEPAPEPATEPAPEP----------APEPATESAPEP-TPEPALESVP 135
Query: 112 QPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ-PLP 170
+P P + A AP EP P P P P++ P+ +P LQ P+
Sbjct: 136 EPAPELTPEVAPELAP-----EPTPEPVTELAP---EFCPEAAPEFRPSPAPCLLQCPVD 187
Query: 171 TPVLTIAPHPGVQPQLAPQQP 191
T + P P +P+ P
Sbjct: 188 TRERGLKTSPSPSPSPSPRTP 208
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/146 (30%), Positives = 54/146 (36%), Gaps = 9/146 (6%)
Query: 25 EEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPA 84
E L E E + A+ A T P EP E P P PA AP P TP
Sbjct: 72 ESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEP---TPE 128
Query: 85 P-LTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQV 143
P L +P P +P+ P P P LAP + AP P+P P Q
Sbjct: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAP-EFCPEAAPEF---RPSPAPCLLQC 184
Query: 144 PTPAPLLPDSKATIPPNGSPKPLQPL 169
P K + P+ SP P P+
Sbjct: 185 PVDT-RERGLKTSPSPSPSPSPRTPM 209
Score = 37.0 bits (84), Expect = 0.050
Identities = 38/145 (26%), Positives = 49/145 (33%), Gaps = 20/145 (13%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAP-LPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP 410
PP + P P LL P P P P L P P P S + + + + P
Sbjct: 34 PPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEP 93
Query: 411 APPP---PPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
AP P P PA P PA AT T +++V P +
Sbjct: 94 APEPATEPAPEPATEPAPEPAPEPATESA-------PEPTPEPALESVPE----PAPELT 142
Query: 468 AHIAPS-----APSPAVQLAPATPP 487
+AP P P +LAP P
Sbjct: 143 PEVAPELAPEPTPEPVTELAPEFCP 167
Score = 36.6 bits (83), Expect = 0.065
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 18/90 (20%)
Query: 359 PQPELLKSTLPPPSTTPAPLP---------PHPHPHPHSVALPPAHLPVQQQQPQQKTPL 409
P PE P P+T PAP P P P P P ++P + + + P
Sbjct: 93 PAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPE 152
Query: 410 PAPPP---------PPAAPAQTLVPAPAHL 430
P P P P AAP PAP L
Sbjct: 153 PTPEPVTELAPEFCPEAAPEFRPSPAPCLL 182
Score = 31.2 bits (69), Expect = 2.7
Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 392 PPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAP 427
PP + P+ P P PPPPPA P PAP
Sbjct: 13 PPQDGEQPAESPEPPPPWPPPPPPPAPP-----PAP 43
Score = 30.8 bits (68), Expect = 3.6
Identities = 31/96 (32%), Positives = 35/96 (36%), Gaps = 8/96 (8%)
Query: 110 AAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKP-LQP 168
AA AP Q A P P P P P PAP L S+A+ P P P L P
Sbjct: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLL-SEASPEPIPEPCPELAP 63
Query: 169 LPTPVLT------IAPHPGVQPQLAPQQPPPPTLGT 198
P P T + P +P P P P T
Sbjct: 64 GPCPEATSESATELYTEPTPEPATEPASEPAPEPAT 99
Score = 30.8 bits (68), Expect = 3.6
Identities = 38/166 (22%), Positives = 53/166 (31%), Gaps = 21/166 (12%)
Query: 365 KSTLPPPS---TTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQ 421
+ T PP +P PP P P P PP P+ + A P P P
Sbjct: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSE---------ASPEPIPEPCP 59
Query: 422 TLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPS-----APS 476
L P P A S +T T + + P + A AP
Sbjct: 60 ELAPGPC---PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPE 116
Query: 477 PAVQLAPATPPIGHITVHPATLNHVA-HLGSQLPLYPQPVAVSHIA 521
PA + AP P + P + + +L P P V+ +A
Sbjct: 117 PATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELA 162
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/180 (31%), Positives = 72/180 (40%), Gaps = 26/180 (14%)
Query: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPI---------PVVTNSPQPLPPPP 105
+++P + P +P PP AP + P PL +P P++ P P PPP
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464
Query: 106 PLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKP 165
P P P P P QPAL P L AP PS P P PL P PP P P
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPL----VAPTPSS---PPPPPLPPP-----PPPAMPSP 1512
Query: 166 LQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEV-----KSSEQKKRPGGIG 220
P P +A P +P+ P P L LA +E ++ E+ GG G
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
Score = 70.5 bits (171), Expect = 4e-12
Identities = 49/111 (44%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 43 ANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPP---LATPAPLTVIPIPVVTNSPQ 99
ANS L E+P PP P P PPP PPPP L +P PL V P P + P
Sbjct: 1442 ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPL-VAPTP-SSPPPP 1499
Query: 100 PLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEP-APLPSRPQVPTPAPL 149
PLPPPPP PA P P P A + AP +EP AP P P++P PL
Sbjct: 1500 PLPPPPP-PAMPSPPPPPPPAAAPLAAPP---EEPAAPSPEDPELPDTRPL 1546
Score = 60.8 bits (146), Expect = 3e-09
Identities = 70/273 (25%), Positives = 96/273 (35%), Gaps = 60/273 (21%)
Query: 161 GSPKPLQPLPTPVLTIAPHPGVQPQ--LAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGG 218
G PL P P V P G+QPQ P P PP G L A E SE G
Sbjct: 1302 GLTPPLSP-PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL----G 1356
Query: 219 IGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEY 278
+G +L+ E LKRN+ + +
Sbjct: 1357 LGCPSPCKRLD-----------EELKRNLETLPSFSSD---------------------- 1383
Query: 279 EHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVL--RQTGQPEDDQASTSTASEGE 336
E + +A+ + +L+ +S + L+ + + T P+ + + A G
Sbjct: 1384 --EEDSVAKNR--------DLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGP 1433
Query: 337 DNIDEDMEEDRAGLG-PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAH 395
+ + G PP L +P P PPP+ TP P PP P P P P
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPT------PPPAPTPQPQPPPPPPPPQPALPSPPP 1487
Query: 396 LPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPA 428
L PLP PPPPPA P+ P PA
Sbjct: 1488 LVAPTPSSPPPPPLP-PPPPPAMPSPPPPPPPA 1519
Score = 58.2 bits (139), Expect = 2e-08
Identities = 90/377 (23%), Positives = 131/377 (34%), Gaps = 79/377 (20%)
Query: 78 PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPL 137
PPLA P T++P PP PAAA P P P P L A EP L
Sbjct: 1408 PPLAGPKD---------TSTPDG---PPLAPAAAVPGP--PPLPGLPSANSNGTPEPPLL 1453
Query: 138 PSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPH-------PGVQPQLAPQQ 190
+P PTP P PP P+P P P P++ P P P P
Sbjct: 1454 EEKPP-PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Query: 191 PPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNV 250
PPPP LA E ++ + P TR +H ++ A C ET
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAA---VCGET-------- 1561
Query: 251 DDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVL 310
D++ + + + R+ E+ E + K+A Q + +
Sbjct: 1562 DEEAGESGG---------EGIFRERDEFVIRAEDIPSLKLALQTG--------REPPPIW 1604
Query: 311 EIDRVLRQTGQPE--DDQASTSTASE-----GEDN----------IDEDMEEDRAGLGPP 353
+ + L Q PE D Q S G+ ++ ++D +
Sbjct: 1605 RVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCAR 1664
Query: 354 KLSHRPQPELLKS------TLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
K HRP + +S S+ P P P P P P + ++P ++T
Sbjct: 1665 KPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPE------KTTSEKPPEQT 1718
Query: 408 PLPAPPPPPAAPAQTLV 424
P A P PPA +L+
Sbjct: 1719 PETAMPEPPAPEKPSLL 1735
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/144 (29%), Positives = 59/144 (40%), Gaps = 7/144 (4%)
Query: 65 LPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPP--LPAAAQPLPLAPRQPA 122
L SPP PPP P P ++ + P LPPPPP LP+ P +
Sbjct: 760 LQKSPPPPPPTAQS--TQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSAS 817
Query: 123 LVGAPGL--SIKEPAPLPSRPQVPTPAPLLPDSKATIPPNG-SPKPLQPLPTPVLTIAPH 179
VG L + ++ AP P P P P P+ +A + +G P P P ++ P
Sbjct: 818 KVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPP 877
Query: 180 PGVQPQLAPQQPPPPTLGTLKLAP 203
+Q L +P PP G + P
Sbjct: 878 GAMQELLGALEPLPPAPGDTGVGP 901
Score = 43.1 bits (100), Expect = 7e-04
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 30/160 (18%)
Query: 63 PPLPLSPPAPPPAPPPPLATPAP--------LTVIPIPVVTNSPQPLPPPPPLPAAAQPL 114
P LPL P PPP P + + AP + V + T P PPPPP P P
Sbjct: 788 PDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP---PPP 844
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPN------GSPKPLQP 168
P+ + A + + GL EPA P+P L ++ PP G+ +PL P
Sbjct: 845 PMPLQLEAHLRSHGL---EPA---------APSPRLRPEESLDPPGAMQELLGALEPLPP 892
Query: 169 LPTPVLTIAPH-PGVQPQLAPQQPPPPTLGTLKLAPAEEV 207
P P+ G P A + P P + P +
Sbjct: 893 APGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI 932
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 19/116 (16%)
Query: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP-----QPLPPP---PP 106
+E + P P PP PPP PP PL A L + SP + L PP
Sbjct: 824 LEPATRDGAPQPPPPPPPPP-PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE 882
Query: 107 LPAAAQPLPLAPRQPALVGAPGLSIKEPA-----PLPSRPQVPTPAPL----LPDS 153
L A +PLP AP VG P K+PA P P + P PL PDS
Sbjct: 883 LLGALEPLPPAPGDTG-VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS 937
Score = 40.4 bits (93), Expect = 0.005
Identities = 109/488 (22%), Positives = 155/488 (31%), Gaps = 142/488 (29%)
Query: 60 MEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPV-VTNSPQPL------------PPPPP 106
+++ P +PP PPP PPPP P + P+ + P+ L PP
Sbjct: 1030 IQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
Query: 107 LPA-----------------AAQPLPLAPR-----------QPALVGAPGLSIKEPAPLP 138
P + L PR +PAL + P P P
Sbjct: 1090 TPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGP 1149
Query: 139 SRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQP------- 191
P+ P P G P+ ++PL P T P P ++P
Sbjct: 1150 DGPRRRGRKPTKAKRDGPPRPRGRPR-IRPLEVPT-TAGPASASTPTDGAKKPRGRGRGR 1207
Query: 192 --PPPTLGTLKLAPAEEVKSSEQKKRPG-GIGTRE-------VHNKLEKNRRAHLKECFE 241
G +L P + +K + G G+GT HN L+ + E
Sbjct: 1208 GRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTR------E 1261
Query: 242 TLKRNIPNVDDKKTSNLS-VLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 300
++ I V++K+ S + + L +++S KR Y+ A L
Sbjct: 1262 KIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQ-----------------AGLT 1304
Query: 301 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNID---EDMEEDRAGLGPPKLSH 357
LS V QP A G + E E + GLG P
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCK 1364
Query: 358 RPQPELLKS--TLP-----------------------------PPSTTP----------- 375
R EL ++ TLP PP P
Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPL 1424
Query: 376 APLPPHPHPHPHSVALPPAHL------PVQQQQPQQKTPLPAP-----PPPPAAPAQTLV 424
AP P P P LP A+ P+ +++P TP PAP PPPP P Q +
Sbjct: 1425 APAAAVPGP-PPLPGLPSANSNGTPEPPLLEEKP-PPTPPPAPTPQPQPPPPPPPPQPAL 1482
Query: 425 PAPAHLVA 432
P+P LVA
Sbjct: 1483 PSPPPLVA 1490
Score = 38.1 bits (87), Expect = 0.022
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 20/118 (16%)
Query: 409 LPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIA 468
L PPPP AQ+ P P L+ AGG + VL P + +
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPL----------------VLPPPPPQLLP 803
Query: 469 HIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSH 526
+ APSP +P+ +G + PAT + P P P+ + AH SH
Sbjct: 804 SVLSHAPSP----SPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSH 857
Score = 38.1 bits (87), Expect = 0.022
Identities = 49/204 (24%), Positives = 67/204 (32%), Gaps = 65/204 (31%)
Query: 369 PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPA 428
PPP P+ L P P P + + L + + P P PPPPP P Q A
Sbjct: 797 PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ----LEA 852
Query: 429 HLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPI 488
HL +H + P+APSP ++ + P
Sbjct: 853 HL---------------RSHG--------------------LEPAAPSPRLRPEESLDP- 876
Query: 489 GHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVG 548
P + + LG+ PL P P G G+GPP + PA G
Sbjct: 877 ------PGAMQEL--LGALEPLPPAP----------------GDTGVGPPNSEGKDPA-G 911
Query: 549 AQVVHHPQLVGQTVLNPVTMVTMP 572
A PQ P+T + P
Sbjct: 912 AYRSPSPQGTKAPRFVPLTSICFP 935
Score = 37.7 bits (86), Expect = 0.029
Identities = 32/96 (33%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 335 GEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLP---------PPSTTPAPLPPHPHPH 385
G+ ED + +AG GPP P P P P T L P+ P
Sbjct: 963 GKAGPPEDEGDPKAGAGPP-----PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
Query: 386 -PHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 420
P +V P L +Q Q P P PPPPP APA
Sbjct: 1018 LPSTVNAEPLGL-IQSGPHQAAPPPPPPPPPPPAPA 1052
Score = 37.4 bits (85), Expect = 0.038
Identities = 81/384 (21%), Positives = 122/384 (31%), Gaps = 76/384 (19%)
Query: 61 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ 120
E P L L P PP P + + P+ ++ + P PPPP P P P + +
Sbjct: 1004 ETPGLGLDPNKPPELP-------STVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
Query: 121 PALVGAPGLSIKEPAPLPSR---------PQVPTPAPL--------LPDSKATIPPNGSP 163
L S K L + P TP L + KA +P +
Sbjct: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
Query: 164 KPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTRE 223
P + LP V + P + P LG + P PG G R
Sbjct: 1117 NP-RRLPDLVSSCRSRPALSP-----------LGDIDFCP----------PNPGPDGPRR 1154
Query: 224 VHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEME 283
K K +R R P + + + +A K K +
Sbjct: 1155 RGRKPTKAKRDG-----PPRPRGRPRIRPLEVPTTAGPASASTPTDGAK-KPRGRGRGRG 1208
Query: 284 RLAREKIATQ-QRLAELKHELS-----QWMDVLEIDRVLRQTGQPEDDQASTSTASEGED 337
R A E T+ + L LK +LS + + D + D +
Sbjct: 1209 RKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIK 1268
Query: 338 NIDEDMEEDRAGLGPPKL----SHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPP 393
++E E ++G L S + P L ++ L PP + P +PP
Sbjct: 1269 EVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPP------------- 1315
Query: 394 AHLPVQQQQPQQKTPLPAPPPPPA 417
+P + QPQ P PPP+
Sbjct: 1316 -SVPARGLQPQPPATPAVPHPPPS 1338
Score = 37.0 bits (84), Expect = 0.050
Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 5/82 (6%)
Query: 71 APPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLS 130
A P PPP A P TVI S QP PPPPP A L P++ L+
Sbjct: 271 AAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLA 330
Query: 131 IK-----EPAPLPSRPQVPTPA 147
EP+P P P+
Sbjct: 331 CSPLGGGEPSPGAGEPSKAGPS 352
Score = 36.6 bits (83), Expect = 0.065
Identities = 34/126 (26%), Positives = 47/126 (37%), Gaps = 21/126 (16%)
Query: 68 SPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAP 127
+PP PAPPP TP T PP P A P P AP +P+L+ P
Sbjct: 1691 APPPKAPAPPPKPETPEKTT------------SEKPPEQTPETAMPEPPAPEKPSLL-RP 1737
Query: 128 GLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLA 187
KE + +R + P + T +P + L T + P +P
Sbjct: 1738 VEKEKEKEKV-TRGERPLRGERATSGRQT-------RPERSLATGQPATSRLPKARPTKV 1789
Query: 188 PQQPPP 193
+PPP
Sbjct: 1790 KAEPPP 1795
Score = 33.1 bits (74), Expect = 0.72
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 136 PLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQ-PQLAPQQPPPP 194
P+P R P+ + PP P +P TP T + P Q P+ A +PP P
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKP-ETPEKTTSEKPPEQTPETAMPEPPAP 1729
Query: 195 TLGTLKLAPAEEVKSSEQKKR 215
+L L P E+ K E+ R
Sbjct: 1730 EKPSL-LRPVEKEKEKEKVTR 1749
Score = 32.7 bits (73), Expect = 0.94
Identities = 35/120 (29%), Positives = 39/120 (32%), Gaps = 38/120 (31%)
Query: 368 LPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQ---------------QQQPQQ---KTPL 409
L P PA PP+ P P PP HLP Q Q PQ
Sbjct: 214 LGPAGLGPAQTPPY-RPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAA 272
Query: 410 PAPPPPP-AAPAQTLV---------------PAPAHLV---ATAGGGSTVIAHTATTHAS 450
P PPPP A P Q V P PAH + + GG + H A S
Sbjct: 273 PGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACS 332
Score = 32.3 bits (72), Expect = 1.2
Identities = 48/201 (23%), Positives = 60/201 (29%), Gaps = 34/201 (16%)
Query: 357 HRPQPE--LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP 414
H P P + LP ST P+ + HP S P PV Q P P
Sbjct: 123 HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRP--FPVPSSLSLQDPPFSPPAN 180
Query: 415 PPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSA 474
+P L P+ A T + + + GP G A P
Sbjct: 181 GLLSPHDVLHLKPSQ------------APTVPSSLGFERLAGGGVLGPAGLGPAQTPPYR 228
Query: 475 PSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVN-GTA 533
P P P PP HL +Q L A + A S Q N A
Sbjct: 229 PGPP---DPPPPP--------------RHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 534 GLGPPATVMAKPAVGAQVVHH 554
GPP A P + H+
Sbjct: 272 APGPPPPERALPRQDTVIKHY 292
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/101 (28%), Positives = 35/101 (34%), Gaps = 26/101 (25%)
Query: 352 PPKLSHRPQPELLKSTL-----------------PPPSTTPAPLPPHPHPHPHSVALPPA 394
P LSH P P S + PPP P P+P H S L PA
Sbjct: 803 PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPA 862
Query: 395 HLPVQQQQPQQKTPLP--------APPPPPAAPAQTLVPAP 427
P + +P++ P A P P AP T V P
Sbjct: 863 -APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPP 902
Score = 30.4 bits (67), Expect = 4.7
Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTP 408
G PP+ + Q ++K P S P P PP H H ++ ++ + + +P
Sbjct: 274 GPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSP 333
Query: 409 LPAPPPPPAAPAQTLVPAPAHLVATAGGGST 439
L P P A + P+ A A G +T
Sbjct: 334 LGGGEPSPGA-GEPSKAGPSGATAGASGRAT 363
Score = 29.6 bits (65), Expect = 8.0
Identities = 31/106 (29%), Positives = 33/106 (31%), Gaps = 15/106 (14%)
Query: 67 LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGA 126
L P PA PP P P P PPPPP Q LA A A
Sbjct: 214 LGPAGLGPAQTPPYR-PGP--------------PDPPPPPRHLPTQFNLLASSSAAAAAA 258
Query: 127 PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTP 172
S + + P P P LP I P QP P P
Sbjct: 259 EQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPP 304
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 72.8 bits (177), Expect = 8e-13
Identities = 61/198 (30%), Positives = 79/198 (39%), Gaps = 35/198 (17%)
Query: 6 LLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSL------ARLAHTLPVEEPR 59
L++A + ++ Q QR Q + E +Q A + A+ L V +PR
Sbjct: 353 LVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPR 412
Query: 60 MEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA-AQPLPLAP 118
L PPP PPPPL +P + P P PPPPPLP+ A+ LP AP
Sbjct: 413 A----LEQQASTPPPPPPPPL----------LPGSSAEPPPPPPPPPLPSVGAKALPTAP 458
Query: 119 RQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
P L G ++ P P P LP S +PP P P P P + P
Sbjct: 459 PPPPLPGLGAMA----------PPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 179 HPGVQPQLAPQQPPPPTL 196
G P PPPP L
Sbjct: 509 GMG----WGPPPPPPPLL 522
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/105 (34%), Positives = 40/105 (38%), Gaps = 18/105 (17%)
Query: 345 EDRAGLGPPKLSHRPQPELL--KSTLPPPSTTPAPLP----------PHPHPHPHSVALP 392
E +A PP P P LL S PPP P PLP P P P P A+
Sbjct: 415 EQQASTPPPP----PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 393 PAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P+ P LP PPPP P P P L+ G G
Sbjct: 471 PPAPPLPPPLPGSCEFLP--PPPPPLPGLGCPPPPPPLLPGMGWG 513
Score = 38.9 bits (89), Expect = 0.013
Identities = 31/81 (38%), Positives = 33/81 (40%), Gaps = 20/81 (24%)
Query: 50 AHTLPVEEPRMEAPPLP----LSPPAPPPAPP--------PPLATPAPLTVIPIPVVTNS 97
A LP P PPLP ++PPAPP PP PP P P P P
Sbjct: 451 AKALPTAPP---PPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL 507
Query: 98 PQ----PLPPPPP-LPAAAQP 113
P P PPPPP LP P
Sbjct: 508 PGMGWGPPPPPPPLLPCTCSP 528
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/90 (34%), Positives = 31/90 (34%), Gaps = 22/90 (24%)
Query: 367 TLPPPSTTPA------PLPPHPHPHPHSVAL---PPAHLPVQQQQPQQKTPLPA------ 411
T PPP P P PP P P P S PP LP P LP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 412 PPPPPAAPAQTLVPAPAHLVATAGGGSTVI 441
PPPPP P P AGG VI
Sbjct: 516 PPPPPLLPCTCSPP-------VAGGMEEVI 538
Score = 32.7 bits (73), Expect = 0.94
Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 11/82 (13%)
Query: 355 LSHRPQPELLKSTLP----PPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP 410
+ H +LK + P ++TP P PP P S PP P K
Sbjct: 397 VDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPT 456
Query: 411 APPPPP-------AAPAQTLVP 425
APPPPP A PA L P
Sbjct: 457 APPPPPLPGLGAMAPPAPPLPP 478
Score = 30.8 bits (68), Expect = 3.6
Identities = 54/258 (20%), Positives = 83/258 (32%), Gaps = 54/258 (20%)
Query: 312 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP 371
++R+L G+P S + ++ ++++ + G P +T P P
Sbjct: 338 VERLLSVKGRPRP-----SPLVKAHKSVQANLDQSQRGSSPQN-----------TTTPKP 381
Query: 372 STT----PAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP-PPAAPAQTLVPA 426
S A P H S ++ P +Q P P PPP P + A+ P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 427 PAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSP----AVQLA 482
P + + G A + T PG +A AP P P L
Sbjct: 442 PPPPLPSVG-------------AKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLP 488
Query: 483 PATPPIGHITVHPATLNHVAHLGSQLPLYPQP----------------VAVSHIAHTLSH 526
P PP+ + P + +G P P P V V+ + H L
Sbjct: 489 PPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGS 548
Query: 527 QQVNGTAGLGPPATVMAK 544
V + PP M K
Sbjct: 549 AWVPSHRRVNPPTLRMKK 566
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 72.8 bits (177), Expect = 8e-13
Identities = 61/198 (30%), Positives = 79/198 (39%), Gaps = 35/198 (17%)
Query: 6 LLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSL------ARLAHTLPVEEPR 59
L++A + ++ Q QR Q + E +Q A + A+ L V +PR
Sbjct: 353 LVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPR 412
Query: 60 MEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA-AQPLPLAP 118
L PPP PPPPL +P + P P PPPPPLP+ A+ LP AP
Sbjct: 413 A----LEQQASTPPPPPPPPL----------LPGSSAEPPPPPPPPPLPSVGAKALPTAP 458
Query: 119 RQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
P L G ++ P P P LP S +PP P P P P + P
Sbjct: 459 PPPPLPGLGAMA----------PPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 179 HPGVQPQLAPQQPPPPTL 196
G P PPPP L
Sbjct: 509 GMG----WGPPPPPPPLL 522
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/105 (34%), Positives = 40/105 (38%), Gaps = 18/105 (17%)
Query: 345 EDRAGLGPPKLSHRPQPELL--KSTLPPPSTTPAPLP----------PHPHPHPHSVALP 392
E +A PP P P LL S PPP P PLP P P P P A+
Sbjct: 415 EQQASTPPPP----PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 393 PAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P+ P LP PPPP P P P L+ G G
Sbjct: 471 PPAPPLPPPLPGSCEFLP--PPPPPLPGLGCPPPPPPLLPGMGWG 513
Score = 38.9 bits (89), Expect = 0.013
Identities = 31/81 (38%), Positives = 33/81 (40%), Gaps = 20/81 (24%)
Query: 50 AHTLPVEEPRMEAPPLP----LSPPAPPPAPP--------PPLATPAPLTVIPIPVVTNS 97
A LP P PPLP ++PPAPP PP PP P P P P
Sbjct: 451 AKALPTAPP---PPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL 507
Query: 98 PQ----PLPPPPP-LPAAAQP 113
P P PPPPP LP P
Sbjct: 508 PGMGWGPPPPPPPLLPCTCSP 528
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/90 (34%), Positives = 31/90 (34%), Gaps = 22/90 (24%)
Query: 367 TLPPPSTTPA------PLPPHPHPHPHSVAL---PPAHLPVQQQQPQQKTPLPA------ 411
T PPP P P PP P P P S PP LP P LP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 412 PPPPPAAPAQTLVPAPAHLVATAGGGSTVI 441
PPPPP P P AGG VI
Sbjct: 516 PPPPPLLPCTCSPP-------VAGGMEEVI 538
Score = 32.7 bits (73), Expect = 0.94
Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 11/82 (13%)
Query: 355 LSHRPQPELLKSTLP----PPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP 410
+ H +LK + P ++TP P PP P S PP P K
Sbjct: 397 VDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPT 456
Query: 411 APPPPP-------AAPAQTLVP 425
APPPPP A PA L P
Sbjct: 457 APPPPPLPGLGAMAPPAPPLPP 478
Score = 30.8 bits (68), Expect = 3.6
Identities = 54/258 (20%), Positives = 83/258 (32%), Gaps = 54/258 (20%)
Query: 312 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP 371
++R+L G+P S + ++ ++++ + G P +T P P
Sbjct: 338 VERLLSVKGRPRP-----SPLVKAHKSVQANLDQSQRGSSPQN-----------TTTPKP 381
Query: 372 STT----PAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP-PPAAPAQTLVPA 426
S A P H S ++ P +Q P P PPP P + A+ P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 427 PAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSP----AVQLA 482
P + + G A + T PG +A AP P P L
Sbjct: 442 PPPPLPSVG-------------AKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLP 488
Query: 483 PATPPIGHITVHPATLNHVAHLGSQLPLYPQP----------------VAVSHIAHTLSH 526
P PP+ + P + +G P P P V V+ + H L
Sbjct: 489 PPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGS 548
Query: 527 QQVNGTAGLGPPATVMAK 544
V + PP M K
Sbjct: 549 AWVPSHRRVNPPTLRMKK 566
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 72.0 bits (175), Expect = 1e-12
Identities = 103/422 (24%), Positives = 139/422 (32%), Gaps = 51/422 (12%)
Query: 20 QQRAREEQERLRLEQEREQEQKKANSLA-----RLAHTLPVEEPRMEAPPLPLSPPAPPP 74
++R E ER R E E+ +Q+ ++ + V+ PR A P P P AP
Sbjct: 59 RRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATP-PAPPRAPRG 117
Query: 75 APPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGA-------- 126
AP A P P P PPPPP P AA APR A
Sbjct: 118 APAAAAAAAPP------------PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
Query: 127 -PGLSIKEPAPLPSRPQVPT--PAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQ 183
PG + APL + P P PA P PP PLP P AP Q
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225
Query: 184 PQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETL 243
P PQ PPP G ++ A S + R G G+ +L + R L E
Sbjct: 226 PP-PPQPQPPPEGGAVRAGGAARPVSLREVVRYLG-GSGGAGGRLTRGRVQGLLE----- 278
Query: 244 KRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHEL 303
+ L R + R + R +R K ++R+ E + E
Sbjct: 279 ------EEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEE 332
Query: 304 SQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPEL 363
D E D V + PE D+ + + + ++R P H+ Q E
Sbjct: 333 DDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDE- 391
Query: 364 LKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTL 423
PAP + P +P+P PP PA P
Sbjct: 392 --------GRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADG 443
Query: 424 VP 425
P
Sbjct: 444 TP 445
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/211 (29%), Positives = 79/211 (37%), Gaps = 43/211 (20%)
Query: 308 DVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDED--MEEDRAGLGPPKLSHRPQPELLK 365
D+ I R++R+ PE ++ T +E E I + + G + + R QP
Sbjct: 50 DLERICRMVRRRHGPEPER----TRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG 105
Query: 366 STLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVP 425
+T P P P P P + A PP P PAPPPPP AP P
Sbjct: 106 ATPPAP-----PRAPRGAPAAAAAAAPP--------------PTPAPPPPP-APVAAAAP 145
Query: 426 APAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPAT 485
A A A A A TA Q GP + A +A P+PA A A
Sbjct: 146 ARAPRAAAA-------AATAPPSPGPAQ------PGPRAQRAAPLAAPPPAPAAPPAVA- 191
Query: 486 PPIGHITVHPATLNHVAHLGSQLPLYPQPVA 516
PP G P VA LP PQP A
Sbjct: 192 PPAGPRRAPPPA---VAAREPPLPPPPQPPA 219
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/114 (33%), Positives = 46/114 (40%), Gaps = 13/114 (11%)
Query: 351 GPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP 410
GP + R Q + PP P + P P A PPA V ++P PLP
Sbjct: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRR---APPPA---VAAREP----PLP 212
Query: 411 APPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGG 464
PP PPA P Q P P GG V A A S+ + V + L G GG
Sbjct: 213 PPPQPPAPPQQQQPPPPQPQPPPEGG--AVRAGGAARPVSLREVVRY-LGGSGG 263
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 71.6 bits (174), Expect = 2e-12
Identities = 110/468 (23%), Positives = 150/468 (32%), Gaps = 36/468 (7%)
Query: 40 QKKANSLARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP 98
++ A + + A T P E P P P +P P P PAP T P P
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT---TTKEPAPTTTKSAPTTPKEP 301
Query: 99 QPLPPPPPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT---PAPLLPDSK 154
P P P P +P P P++P + KEPAP P T PAP P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356
Query: 155 ATIPPNGSPKPLQPL-PTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQK 213
A P P P P P P T P P + AP T + AP +
Sbjct: 357 APTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 214 KRPGGIGTREVHNKLEKNRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLK 272
K P T+E K K+ T + K+ + + + A + K
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA---PTTPK 472
Query: 273 RKEKEYEHEMERLAREKI--ATQQRLAELKHELSQWMDVLEIDRVLRQTGQP-EDDQAST 329
E +K+ T ++LA E E+ + P ++ +
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532
Query: 330 STASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLP------PPSTTPAPLPPHP- 382
+T N ++ P P P K T P P+T P P P
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592
Query: 383 HPHPHSVALPPAHLPVQQ--QQPQQKTPLPAPPPPPAAPAQTL--VPAPAHLVATAGGGS 438
P P +A P +P TP P P PA T PAP TA
Sbjct: 593 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 439 TVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATP 486
A T + + +GP AP+ P + AP TP
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK---ETAPTTP 697
Score = 70.5 bits (171), Expect = 4e-12
Identities = 116/500 (23%), Positives = 151/500 (30%), Gaps = 84/500 (16%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLAT--PAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPL 114
P+ AP P P P P T PAP T P P P P P P +P
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP---APLLPDSKATIPPNGSPKPLQPL-P 170
P P++P + KEPAP P TP AP P A P P P P P
Sbjct: 319 PTTPKEPTPT-----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEP 372
Query: 171 TPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEK 230
P T P P + AP T + AP + K P T+E K
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 231 NRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREK 289
K+ T + K+ + + + A + K E +K
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPKETAPTTPKK 489
Query: 290 IA--TQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDR 347
+ T ++LA E + ++ + +T E E+
Sbjct: 490 LTPTTPEKLAPTTPE---------------KPAPTTPEELAPTTPEEPTPTTPEEPAPTT 534
Query: 348 AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P K P PAP P + P P ++P T
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTT 590
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P AP T P T+TT T K
Sbjct: 591 P-KKPAPKELAPTTTKEP------------------TSTTCDKPAPTT--------PKGT 623
Query: 468 AHIAPSAPSPAVQLAPA-TPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSH 526
A P P+P PA T P G P TL A P P+ A +A T +
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKG---TAPTTLKEPA------PTTPKKPAPKELAPTTTK 674
Query: 527 QQVNGTAGLGPPATVMAKPA 546
GP +T KPA
Sbjct: 675 ---------GPTSTTSDKPA 685
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/213 (26%), Positives = 83/213 (38%), Gaps = 18/213 (8%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQ-EQKKANSLARLAHTLPVEEPRMEAP---PLPLSP 69
E +Q + + +E+ +E + E+ A LA + L P+ E P +P
Sbjct: 154 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 213
Query: 70 PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVG---- 125
P P P A+ P P T P P P P + P P++PA
Sbjct: 214 KEPTPTTPKEPASTTPKEPTP---TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP-KPLQPLPTPVLTIAPHPGVQP 184
AP + KEPAP ++ PAP S T P +P P +P PT AP +P
Sbjct: 271 AP-TTPKEPAPTTTK----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 185 -QLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P++P P T P E ++ +K P
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/142 (31%), Positives = 56/142 (39%), Gaps = 12/142 (8%)
Query: 64 PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPLPLAPRQP 121
P L PAP P P P T P + P P P P +P P P++P
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 639
Query: 122 ALV---GAPGLSIKEPAPLPSRPQVPTPAPLLPDSK--ATIPPNGSPKPLQPLPT-PVLT 175
A G ++KEPA P+ P+ P P L P + T + P P P T P
Sbjct: 640 APTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697
Query: 176 IAPHPGVQPQLAPQQP--PPPT 195
P P + AP P PPPT
Sbjct: 698 KEPAPTTPKKPAPTTPETPPPT 719
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 17/196 (8%)
Query: 50 AHTLPVEEPRMEAP----PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPP 104
A T P +EP P P L PAP P P P T P ++ P P P
Sbjct: 632 APTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 105 PPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP 163
P +P P P++PA P P+ +V TP + P+ S
Sbjct: 691 ETAPTTPKEPAPTTPKKPA-------PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743
Query: 164 KPLQPLPTP-VLTIAP-HPGVQPQLAPQQPPPPTLGTLKLAPAE-EVKSSEQKKRPGGIG 220
L PTP L +P PGV P P T K E +++++ +
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Query: 221 TREVHNKLEKNRRAHL 236
T+E EK + +
Sbjct: 804 TKETATTTEKTTESKI 819
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 45 SLARLAHTLPVEEPRMEAPPL----PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP 100
+L A T P + E P P S + PAP P T P P P P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710
Query: 101 LPPPPPLPAAAQ-PLPLAPRQPALV------GAPGLSIKEPAP-----LPSRPQVP---T 145
P P P ++ P ++P + P LS EP P P P VP T
Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKT 769
Query: 146 PAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
PA P+ T + + L+ P T AP
Sbjct: 770 PAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 801
Score = 36.2 bits (82), Expect = 0.085
Identities = 42/177 (23%), Positives = 53/177 (29%), Gaps = 17/177 (9%)
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGP-------PKLSHRPQPELLKSTLPPPSTTPAPLP 379
A T+T D+ G P P P P K T P PAP
Sbjct: 600 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 380 PHPHPHPHSVALPPAHLPVQ--QQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P P +A P +P TP P P PA T PA
Sbjct: 660 PKK-PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 438 STVIAHTATT-------HASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
+T T TT H S ++ + P K + + P + AT P
Sbjct: 719 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 775
Score = 35.4 bits (80), Expect = 0.15
Identities = 39/141 (27%), Positives = 45/141 (31%), Gaps = 19/141 (13%)
Query: 353 PKLSHRPQPELLKSTL-----PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P KS P P+TT P P P + PA + K
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P P AP PAP +T T TT T K
Sbjct: 301 PAPTTPKKP-APTTPKEPAP----------TTPKEPTPTTPKEPAPTTKEPAP-TTPKEP 348
Query: 468 AHIAPSAPSPAV--QLAPATP 486
A AP P+P + AP TP
Sbjct: 349 APTAPKKPAPTTPKEPAPTTP 369
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/168 (25%), Positives = 59/168 (35%), Gaps = 8/168 (4%)
Query: 321 QPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPP 380
Q D +T+++ +I++ +D A K+ +P P+ +T P TTP P
Sbjct: 161 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTS--KVLAKPTPKAETTTKGPALTTPKEPTP 218
Query: 381 HPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTV 440
P S P P + PAP +AP PAP A
Sbjct: 219 TTPKEPASTT-PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 441 IAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAV--QLAPATP 486
A T TT T P K A P P+P + AP TP
Sbjct: 278 PAPT-TTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTP 322
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 71.6 bits (174), Expect = 2e-12
Identities = 110/468 (23%), Positives = 150/468 (32%), Gaps = 36/468 (7%)
Query: 40 QKKANSLARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP 98
++ A + + A T P E P P P +P P P PAP T P P
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT---TTKEPAPTTTKSAPTTPKEP 342
Query: 99 QPLPPPPPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT---PAPLLPDSK 154
P P P P +P P P++P + KEPAP P T PAP P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397
Query: 155 ATIPPNGSPKPLQPL-PTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQK 213
A P P P P P P T P P + AP T + AP +
Sbjct: 398 APTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 214 KRPGGIGTREVHNKLEKNRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLK 272
K P T+E K K+ T + K+ + + + A + K
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA---PTTPK 513
Query: 273 RKEKEYEHEMERLAREKI--ATQQRLAELKHELSQWMDVLEIDRVLRQTGQP-EDDQAST 329
E +K+ T ++LA E E+ + P ++ +
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573
Query: 330 STASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLP------PPSTTPAPLPPHP- 382
+T N ++ P P P K T P P+T P P P
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633
Query: 383 HPHPHSVALPPAHLPVQQ--QQPQQKTPLPAPPPPPAAPAQTL--VPAPAHLVATAGGGS 438
P P +A P +P TP P P PA T PAP TA
Sbjct: 634 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 439 TVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATP 486
A T + + +GP AP+ P + AP TP
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK---ETAPTTP 738
Score = 70.5 bits (171), Expect = 4e-12
Identities = 116/500 (23%), Positives = 151/500 (30%), Gaps = 84/500 (16%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLAT--PAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPL 114
P+ AP P P P P T PAP T P P P P P P +P
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP---APLLPDSKATIPPNGSPKPLQPL-P 170
P P++P + KEPAP P TP AP P A P P P P P
Sbjct: 360 PTTPKEPTPT-----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEP 413
Query: 171 TPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEK 230
P T P P + AP T + AP + K P T+E K
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 231 NRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREK 289
K+ T + K+ + + + A + K E +K
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPKETAPTTPKK 530
Query: 290 IA--TQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDR 347
+ T ++LA E + ++ + +T E E+
Sbjct: 531 LTPTTPEKLAPTTPE---------------KPAPTTPEELAPTTPEEPTPTTPEEPAPTT 575
Query: 348 AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P K P PAP P + P P ++P T
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTT 631
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P AP T P T+TT T K
Sbjct: 632 P-KKPAPKELAPTTTKEP------------------TSTTCDKPAPTT--------PKGT 664
Query: 468 AHIAPSAPSPAVQLAPA-TPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSH 526
A P P+P PA T P G P TL A P P+ A +A T +
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKG---TAPTTLKEPA------PTTPKKPAPKELAPTTTK 715
Query: 527 QQVNGTAGLGPPATVMAKPA 546
GP +T KPA
Sbjct: 716 ---------GPTSTTSDKPA 726
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/213 (26%), Positives = 83/213 (38%), Gaps = 18/213 (8%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQ-EQKKANSLARLAHTLPVEEPRMEAP---PLPLSP 69
E +Q + + +E+ +E + E+ A LA + L P+ E P +P
Sbjct: 195 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 254
Query: 70 PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVG---- 125
P P P A+ P P T P P P P + P P++PA
Sbjct: 255 KEPTPTTPKEPASTTPKEPTP---TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP-KPLQPLPTPVLTIAPHPGVQP 184
AP + KEPAP ++ PAP S T P +P P +P PT AP +P
Sbjct: 312 AP-TTPKEPAPTTTK----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 185 -QLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P++P P T P E ++ +K P
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/142 (31%), Positives = 56/142 (39%), Gaps = 12/142 (8%)
Query: 64 PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPLPLAPRQP 121
P L PAP P P P T P + P P P P +P P P++P
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 680
Query: 122 ALV---GAPGLSIKEPAPLPSRPQVPTPAPLLPDSK--ATIPPNGSPKPLQPLPT-PVLT 175
A G ++KEPA P+ P+ P P L P + T + P P P T P
Sbjct: 681 APTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738
Query: 176 IAPHPGVQPQLAPQQP--PPPT 195
P P + AP P PPPT
Sbjct: 739 KEPAPTTPKKPAPTTPETPPPT 760
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 17/196 (8%)
Query: 50 AHTLPVEEPRMEAP----PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPP 104
A T P +EP P P L PAP P P P T P ++ P P P
Sbjct: 673 APTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 105 PPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP 163
P +P P P++PA P P+ +V TP + P+ S
Sbjct: 732 ETAPTTPKEPAPTTPKKPA-------PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784
Query: 164 KPLQPLPTP-VLTIAP-HPGVQPQLAPQQPPPPTLGTLKLAPAE-EVKSSEQKKRPGGIG 220
L PTP L +P PGV P P T K E +++++ +
Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Query: 221 TREVHNKLEKNRRAHL 236
T+E EK + +
Sbjct: 845 TKETATTTEKTTESKI 860
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 45 SLARLAHTLPVEEPRMEAPPL----PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP 100
+L A T P + E P P S + PAP P T P P P P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751
Query: 101 LPPPPPLPAAAQ-PLPLAPRQPALV------GAPGLSIKEPAP-----LPSRPQVP---T 145
P P P ++ P ++P + P LS EP P P P VP T
Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKT 810
Query: 146 PAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
PA P+ T + + L+ P T AP
Sbjct: 811 PAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 842
Score = 36.2 bits (82), Expect = 0.085
Identities = 42/177 (23%), Positives = 53/177 (29%), Gaps = 17/177 (9%)
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGP-------PKLSHRPQPELLKSTLPPPSTTPAPLP 379
A T+T D+ G P P P P K T P PAP
Sbjct: 641 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 380 PHPHPHPHSVALPPAHLPVQ--QQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P P +A P +P TP P P PA T PA
Sbjct: 701 PKK-PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 438 STVIAHTATT-------HASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
+T T TT H S ++ + P K + + P + AT P
Sbjct: 760 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 816
Score = 35.4 bits (80), Expect = 0.15
Identities = 39/141 (27%), Positives = 45/141 (31%), Gaps = 19/141 (13%)
Query: 353 PKLSHRPQPELLKSTL-----PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P KS P P+TT P P P + PA + K
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P P AP PAP +T T TT T K
Sbjct: 342 PAPTTPKKP-APTTPKEPAP----------TTPKEPTPTTPKEPAPTTKEPAP-TTPKEP 389
Query: 468 AHIAPSAPSPAV--QLAPATP 486
A AP P+P + AP TP
Sbjct: 390 APTAPKKPAPTTPKEPAPTTP 410
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/168 (25%), Positives = 59/168 (35%), Gaps = 8/168 (4%)
Query: 321 QPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPP 380
Q D +T+++ +I++ +D A K+ +P P+ +T P TTP P
Sbjct: 202 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTS--KVLAKPTPKAETTTKGPALTTPKEPTP 259
Query: 381 HPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTV 440
P S P P + PAP +AP PAP A
Sbjct: 260 TTPKEPASTT-PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 441 IAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAV--QLAPATP 486
A T TT T P K A P P+P + AP TP
Sbjct: 319 PAPT-TTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTP 363
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 71.6 bits (174), Expect = 2e-12
Identities = 110/468 (23%), Positives = 150/468 (32%), Gaps = 36/468 (7%)
Query: 40 QKKANSLARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP 98
++ A + + A T P E P P P +P P P PAP T P P
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT---TTKEPAPTTTKSAPTTPKEP 394
Query: 99 QPLPPPPPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT---PAPLLPDSK 154
P P P P +P P P++P + KEPAP P T PAP P
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449
Query: 155 ATIPPNGSPKPLQPL-PTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQK 213
A P P P P P P T P P + AP T + AP +
Sbjct: 450 APTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 214 KRPGGIGTREVHNKLEKNRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLK 272
K P T+E K K+ T + K+ + + + A + K
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA---PTTPK 565
Query: 273 RKEKEYEHEMERLAREKI--ATQQRLAELKHELSQWMDVLEIDRVLRQTGQP-EDDQAST 329
E +K+ T ++LA E E+ + P ++ +
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625
Query: 330 STASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLP------PPSTTPAPLPPHP- 382
+T N ++ P P P K T P P+T P P P
Sbjct: 626 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685
Query: 383 HPHPHSVALPPAHLPVQQ--QQPQQKTPLPAPPPPPAAPAQTL--VPAPAHLVATAGGGS 438
P P +A P +P TP P P PA T PAP TA
Sbjct: 686 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 745
Query: 439 TVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATP 486
A T + + +GP AP+ P + AP TP
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK---ETAPTTP 790
Score = 70.5 bits (171), Expect = 4e-12
Identities = 116/500 (23%), Positives = 151/500 (30%), Gaps = 84/500 (16%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLAT--PAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPL 114
P+ AP P P P P T PAP T P P P P P P +P
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP---APLLPDSKATIPPNGSPKPLQPL-P 170
P P++P + KEPAP P TP AP P A P P P P P
Sbjct: 412 PTTPKEPTPT-----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEP 465
Query: 171 TPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEK 230
P T P P + AP T + AP + K P T+E K
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 231 NRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREK 289
K+ T + K+ + + + A + K E +K
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPKETAPTTPKK 582
Query: 290 IA--TQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDR 347
+ T ++LA E + ++ + +T E E+
Sbjct: 583 LTPTTPEKLAPTTPE---------------KPAPTTPEELAPTTPEEPTPTTPEEPAPTT 627
Query: 348 AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P K P PAP P + P P ++P T
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTT 683
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P AP T P T+TT T K
Sbjct: 684 P-KKPAPKELAPTTTKEP------------------TSTTCDKPAPTT--------PKGT 716
Query: 468 AHIAPSAPSPAVQLAPA-TPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSH 526
A P P+P PA T P G P TL A P P+ A +A T +
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKG---TAPTTLKEPA------PTTPKKPAPKELAPTTTK 767
Query: 527 QQVNGTAGLGPPATVMAKPA 546
GP +T KPA
Sbjct: 768 ---------GPTSTTSDKPA 778
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/213 (26%), Positives = 83/213 (38%), Gaps = 18/213 (8%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQ-EQKKANSLARLAHTLPVEEPRMEAP---PLPLSP 69
E +Q + + +E+ +E + E+ A LA + L P+ E P +P
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 306
Query: 70 PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVG---- 125
P P P A+ P P T P P P P + P P++PA
Sbjct: 307 KEPTPTTPKEPASTTPKEPTP---TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 363
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP-KPLQPLPTPVLTIAPHPGVQP 184
AP + KEPAP ++ PAP S T P +P P +P PT AP +P
Sbjct: 364 AP-TTPKEPAPTTTK----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 185 -QLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P++P P T P E ++ +K P
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/142 (31%), Positives = 56/142 (39%), Gaps = 12/142 (8%)
Query: 64 PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPLPLAPRQP 121
P L PAP P P P T P + P P P P +P P P++P
Sbjct: 673 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 732
Query: 122 ALV---GAPGLSIKEPAPLPSRPQVPTPAPLLPDSK--ATIPPNGSPKPLQPLPT-PVLT 175
A G ++KEPA P+ P+ P P L P + T + P P P T P
Sbjct: 733 APTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790
Query: 176 IAPHPGVQPQLAPQQP--PPPT 195
P P + AP P PPPT
Sbjct: 791 KEPAPTTPKKPAPTTPETPPPT 812
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 17/196 (8%)
Query: 50 AHTLPVEEPRMEAP----PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPP 104
A T P +EP P P L PAP P P P T P ++ P P P
Sbjct: 725 APTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 105 PPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP 163
P +P P P++PA P P+ +V TP + P+ S
Sbjct: 784 ETAPTTPKEPAPTTPKKPA-------PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836
Query: 164 KPLQPLPTP-VLTIAP-HPGVQPQLAPQQPPPPTLGTLKLAPAE-EVKSSEQKKRPGGIG 220
L PTP L +P PGV P P T K E +++++ +
Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Query: 221 TREVHNKLEKNRRAHL 236
T+E EK + +
Sbjct: 897 TKETATTTEKTTESKI 912
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 45 SLARLAHTLPVEEPRMEAPPL----PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP 100
+L A T P + E P P S + PAP P T P P P P
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 101 LPPPPPLPAAAQ-PLPLAPRQPALV------GAPGLSIKEPAP-----LPSRPQVP---T 145
P P P ++ P ++P + P LS EP P P P VP T
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKT 862
Query: 146 PAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
PA P+ T + + L+ P T AP
Sbjct: 863 PAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 894
Score = 36.2 bits (82), Expect = 0.085
Identities = 42/177 (23%), Positives = 53/177 (29%), Gaps = 17/177 (9%)
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGP-------PKLSHRPQPELLKSTLPPPSTTPAPLP 379
A T+T D+ G P P P P K T P PAP
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 380 PHPHPHPHSVALPPAHLPVQ--QQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P P +A P +P TP P P PA T PA
Sbjct: 753 PKK-PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 438 STVIAHTATT-------HASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
+T T TT H S ++ + P K + + P + AT P
Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 868
Score = 35.4 bits (80), Expect = 0.15
Identities = 39/141 (27%), Positives = 45/141 (31%), Gaps = 19/141 (13%)
Query: 353 PKLSHRPQPELLKSTL-----PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P KS P P+TT P P P + PA + K
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P P AP PAP +T T TT T K
Sbjct: 394 PAPTTPKKP-APTTPKEPAP----------TTPKEPTPTTPKEPAPTTKEPAP-TTPKEP 441
Query: 468 AHIAPSAPSPAV--QLAPATP 486
A AP P+P + AP TP
Sbjct: 442 APTAPKKPAPTTPKEPAPTTP 462
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/168 (25%), Positives = 59/168 (35%), Gaps = 8/168 (4%)
Query: 321 QPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPP 380
Q D +T+++ +I++ +D A K+ +P P+ +T P TTP P
Sbjct: 254 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTS--KVLAKPTPKAETTTKGPALTTPKEPTP 311
Query: 381 HPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTV 440
P S P P + PAP +AP PAP A
Sbjct: 312 TTPKEPASTT-PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370
Query: 441 IAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAV--QLAPATP 486
A T TT T P K A P P+P + AP TP
Sbjct: 371 PAPT-TTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTP 415
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 71.6 bits (174), Expect = 2e-12
Identities = 110/468 (23%), Positives = 150/468 (32%), Gaps = 36/468 (7%)
Query: 40 QKKANSLARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP 98
++ A + + A T P E P P P +P P P PAP T P P
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT---TTKEPAPTTTKSAPTTPKEP 435
Query: 99 QPLPPPPPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPT---PAPLLPDSK 154
P P P P +P P P++P + KEPAP P T PAP P
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490
Query: 155 ATIPPNGSPKPLQPL-PTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQK 213
A P P P P P P T P P + AP T + AP +
Sbjct: 491 APTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 214 KRPGGIGTREVHNKLEKNRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLK 272
K P T+E K K+ T + K+ + + + A + K
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA---PTTPK 606
Query: 273 RKEKEYEHEMERLAREKI--ATQQRLAELKHELSQWMDVLEIDRVLRQTGQP-EDDQAST 329
E +K+ T ++LA E E+ + P ++ +
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666
Query: 330 STASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLP------PPSTTPAPLPPHP- 382
+T N ++ P P P K T P P+T P P P
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726
Query: 383 HPHPHSVALPPAHLPVQQ--QQPQQKTPLPAPPPPPAAPAQTL--VPAPAHLVATAGGGS 438
P P +A P +P TP P P PA T PAP TA
Sbjct: 727 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 786
Query: 439 TVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATP 486
A T + + +GP AP+ P + AP TP
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK---ETAPTTP 831
Score = 70.5 bits (171), Expect = 4e-12
Identities = 116/500 (23%), Positives = 151/500 (30%), Gaps = 84/500 (16%)
Query: 58 PRMEAPPLPLSPPAPPPAPPPPLAT--PAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPL 114
P+ AP P P P P T PAP T P P P P P P +P
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452
Query: 115 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP---APLLPDSKATIPPNGSPKPLQPL-P 170
P P++P + KEPAP P TP AP P A P P P P P
Sbjct: 453 PTTPKEPTPT-----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEP 506
Query: 171 TPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEK 230
P T P P + AP T + AP + K P T+E K
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 231 NRRAHL-KECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREK 289
K+ T + K+ + + + A + K E +K
Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT---TPKEPAPTTPKETAPTTPKK 623
Query: 290 IA--TQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDR 347
+ T ++LA E + ++ + +T E E+
Sbjct: 624 LTPTTPEKLAPTTPE---------------KPAPTTPEELAPTTPEEPTPTTPEEPAPTT 668
Query: 348 AGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P K P PAP P + P P ++P T
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTT 724
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P AP T P T+TT T K
Sbjct: 725 P-KKPAPKELAPTTTKEP------------------TSTTCDKPAPTT--------PKGT 757
Query: 468 AHIAPSAPSPAVQLAPA-TPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSH 526
A P P+P PA T P G P TL A P P+ A +A T +
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKG---TAPTTLKEPA------PTTPKKPAPKELAPTTTK 808
Query: 527 QQVNGTAGLGPPATVMAKPA 546
GP +T KPA
Sbjct: 809 ---------GPTSTTSDKPA 819
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/213 (26%), Positives = 83/213 (38%), Gaps = 18/213 (8%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQ-EQKKANSLARLAHTLPVEEPRMEAP---PLPLSP 69
E +Q + + +E+ +E + E+ A LA + L P+ E P +P
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 347
Query: 70 PAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVG---- 125
P P P A+ P P T P P P P + P P++PA
Sbjct: 348 KEPTPTTPKEPASTTPKEPTP---TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 404
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP-KPLQPLPTPVLTIAPHPGVQP 184
AP + KEPAP ++ PAP S T P +P P +P PT AP +P
Sbjct: 405 AP-TTPKEPAPTTTK----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459
Query: 185 -QLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRP 216
P++P P T P E ++ +K P
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/142 (31%), Positives = 56/142 (39%), Gaps = 12/142 (8%)
Query: 64 PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAA-QPLPLAPRQP 121
P L PAP P P P T P + P P P P +P P P++P
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 773
Query: 122 ALV---GAPGLSIKEPAPLPSRPQVPTPAPLLPDSK--ATIPPNGSPKPLQPLPT-PVLT 175
A G ++KEPA P+ P+ P P L P + T + P P P T P
Sbjct: 774 APTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831
Query: 176 IAPHPGVQPQLAPQQP--PPPT 195
P P + AP P PPPT
Sbjct: 832 KEPAPTTPKKPAPTTPETPPPT 853
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 17/196 (8%)
Query: 50 AHTLPVEEPRMEAP----PLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPP 104
A T P +EP P P L PAP P P P T P ++ P P P
Sbjct: 766 APTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 105 PPLPAA-AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP 163
P +P P P++PA P P+ +V TP + P+ S
Sbjct: 825 ETAPTTPKEPAPTTPKKPA-------PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877
Query: 164 KPLQPLPTP-VLTIAP-HPGVQPQLAPQQPPPPTLGTLKLAPAE-EVKSSEQKKRPGGIG 220
L PTP L +P PGV P P T K E +++++ +
Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Query: 221 TREVHNKLEKNRRAHL 236
T+E EK + +
Sbjct: 938 TKETATTTEKTTESKI 953
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 45 SLARLAHTLPVEEPRMEAPPL----PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQP 100
+L A T P + E P P S + PAP P T P P P P
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 101 LPPPPPLPAAAQ-PLPLAPRQPALV------GAPGLSIKEPAP-----LPSRPQVP---T 145
P P P ++ P ++P + P LS EP P P P VP T
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKT 903
Query: 146 PAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAP 178
PA P+ T + + L+ P T AP
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 935
Score = 36.2 bits (82), Expect = 0.085
Identities = 42/177 (23%), Positives = 53/177 (29%), Gaps = 17/177 (9%)
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGP-------PKLSHRPQPELLKSTLPPPSTTPAPLP 379
A T+T D+ G P P P P K T P PAP
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 380 PHPHPHPHSVALPPAHLPVQ--QQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P P +A P +P TP P P PA T PA
Sbjct: 794 PKK-PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 438 STVIAHTATT-------HASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP 487
+T T TT H S ++ + P K + + P + AT P
Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 909
Score = 35.4 bits (80), Expect = 0.15
Identities = 39/141 (27%), Positives = 45/141 (31%), Gaps = 19/141 (13%)
Query: 353 PKLSHRPQPELLKSTL-----PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKT 407
P P P KS P P+TT P P P + PA + K
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 408 PLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHI 467
P P P P AP PAP +T T TT T K
Sbjct: 435 PAPTTPKKP-APTTPKEPAP----------TTPKEPTPTTPKEPAPTTKEPAP-TTPKEP 482
Query: 468 AHIAPSAPSPAV--QLAPATP 486
A AP P+P + AP TP
Sbjct: 483 APTAPKKPAPTTPKEPAPTTP 503
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/168 (25%), Positives = 59/168 (35%), Gaps = 8/168 (4%)
Query: 321 QPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPP 380
Q D +T+++ +I++ +D A K+ +P P+ +T P TTP P
Sbjct: 295 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTS--KVLAKPTPKAETTTKGPALTTPKEPTP 352
Query: 381 HPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTV 440
P S P P + PAP +AP PAP A
Sbjct: 353 TTPKEPASTT-PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411
Query: 441 IAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAV--QLAPATP 486
A T TT T P K A P P+P + AP TP
Sbjct: 412 PAPT-TTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTP 456
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 70.5 bits (171), Expect = 4e-12
Identities = 110/470 (23%), Positives = 156/470 (33%), Gaps = 141/470 (30%)
Query: 63 PPL-PLSPPAPPPAPPPPLATPAPLTVI------PIPVVTNSPQ--PLPPPPPLPAAAQP 113
PPL P+ P P PAP PP P+P P+P V + P P+P P+P+A P
Sbjct: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAG-P 694
Query: 114 LPLA-PRQPALVGAPGLSIKEPAPLPSR------------------PQVPTPAPLLP--- 151
+P A P P GLS+ +P R TP P +P
Sbjct: 695 VPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDE 754
Query: 152 ------------------------------DSKATIPPNGSPKPLQP------LPTPVLT 175
D I P G P PL P P P+
Sbjct: 755 TFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP-PLPPPPPSGATPPPIAP 813
Query: 176 IAPHPGVQPQLA----------------PQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGI 219
P P A P PPPP G + L P + V PGG
Sbjct: 814 TGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG----TPGGG 869
Query: 220 GTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYE 279
G + L NI + D+++ + + +E+E E
Sbjct: 870 GPPALEEDL--------------TVININSSDEEEEEE-----------EEEEEEEEEEE 904
Query: 280 HEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNI 339
E E E+ ++ E + E ++ + E + G+ E+++ E E
Sbjct: 905 EEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE-----EEEGELEEEEEEEDEEEEEELEE 959
Query: 340 DEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHP------------- 386
ED+E AG G + P P L LPPP +P + P P P P
Sbjct: 960 VEDLEFGTAG-GEVE-EGAPPPPTLPPALPPPE-SPPKVQPEPEPEPGLLLEVEEPGTEE 1016
Query: 387 -----HSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLV 431
+ L P LP Q + +++ PA PPP + AP L+
Sbjct: 1017 ERGADTAPTLAPEALP-SQGEVEREGESPAAGPPPQELVEEEPSAPPTLL 1065
Score = 44.3 bits (103), Expect = 3e-04
Identities = 49/202 (24%), Positives = 76/202 (37%), Gaps = 31/202 (15%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPP 73
E + ++++ EE+E E+E E+E+++ + L E APP P PPA P
Sbjct: 932 EEEFEEEEGELEEEE----EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALP 987
Query: 74 PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKE 133
P PP P+P P P L +P R GA
Sbjct: 988 PPESPPKV---------------QPEPEPEPGLLLEVEEPGTEEER-----GADTAPTLA 1027
Query: 134 PAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP 193
P LPS+ +V +S A PP +P P L + QPPP
Sbjct: 1028 PEALPSQGEVEREG----ESPAAGPPPQELVEEEPSAPPTLL---EEETEDGSDKVQPPP 1080
Query: 194 PTLGTLKLAPAEEVKSSEQKKR 215
T ++ E ++ ++K++
Sbjct: 1081 ETPAEEEMETETEAEALQEKEQ 1102
Score = 43.1 bits (100), Expect = 7e-04
Identities = 33/106 (31%), Positives = 42/106 (39%), Gaps = 9/106 (8%)
Query: 332 ASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVAL 391
AS+ E +++ D +D + P L P P PP TP P+ P P S +
Sbjct: 773 ASDVEISLESD-SDDSVVIVPEGLPPLPPP-------PPSGATPPPIAP-TGPPTASPPV 823
Query: 392 PPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGG 437
P P + P P PPPPP TL P T GGG
Sbjct: 824 PAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGG 869
Score = 36.2 bits (82), Expect = 0.085
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 58 PRMEAPP-LPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPL 107
P E P LP +P PP PPPP P P+T+ P +V PP L
Sbjct: 824 PAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
Score = 35.8 bits (81), Expect = 0.11
Identities = 35/138 (25%), Positives = 45/138 (32%), Gaps = 20/138 (14%)
Query: 355 LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP 414
L+H P L P+ P P P P P PP +P P A P
Sbjct: 630 LTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPS------AGPM 683
Query: 415 PPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGP-----GGKHIAH 469
P A P + P P + G T H + ++ +L GP G
Sbjct: 684 PSAGPMPSAGPVP----SARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPI 739
Query: 470 IAPSAPSPAVQLAPATPP 487
+APS P P PP
Sbjct: 740 LAPSGTPP-----PTIPP 752
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 70.5 bits (171), Expect = 4e-12
Identities = 67/198 (33%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 15 WQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLP-LSPPAPP 73
WQ + QE++ Q + + + ++ P PPLP + PP P
Sbjct: 485 WQGHMKATQSYLQEKVNSFQNMKNQY-----MGNMSMPPPFVPYSQMPPPLPTMPPPVLP 539
Query: 74 PAPPPPLATPA-PLTV----IPIPVVTNS-PQPLPPP--PPLPAAAQPLPLAPRQPALVG 125
P+ PPP+ PA P TV +P PV+ S P +PPP PP ++A P P+ P P +
Sbjct: 540 PSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLP--PPSLS 597
Query: 126 APGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQP--LPTPVLTIAPHP--- 180
+ G P P S P PL P S AT PP G P P P +P P LT AP P
Sbjct: 598 SAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT-PPPGIPPPGVPQGIP-PQLTAAPVPPAS 655
Query: 181 GVQPQLAPQQPPPPTLGT 198
Q P++P P L T
Sbjct: 656 SSQSSQVPEKPRPALLPT 673
Score = 68.9 bits (167), Expect = 1e-11
Identities = 94/421 (22%), Positives = 159/421 (37%), Gaps = 80/421 (19%)
Query: 22 RAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRME---------APPLPLSPPAP 72
+A +E + LR ++E+ Q+ K S ++A LP +E R++ PP PP P
Sbjct: 1458 KAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPP 1517
Query: 73 PPAPPPPLATP-APLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALV------- 124
PP + P AP +PV T P P+PPPPP P P P+ Q + V
Sbjct: 1518 MGKPPGSIVRPSAPPARSSVPV-TRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDE 1576
Query: 125 ----------GAPGLSIK---EPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPT 171
GL+ + E A +PS P +P P
Sbjct: 1577 DSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLP-------------------------PP 1611
Query: 172 PVLTIAPHPGVQPQ-LAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGG--IGTRE---VH 225
PV + P PG P + P PPP T+ ++ +++ ++ P G I R
Sbjct: 1612 PVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPE 1671
Query: 226 NKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKE---YEHEM 282
+ A ++ ++ + P D++++ ++ R R ++ + ++++ +++
Sbjct: 1672 RSTFETEHAGQRDRYDRERDREPYF-DRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDR 1730
Query: 283 ERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTG--QPEDDQASTSTASEGEDNID 340
+R RE+ R + + R+ G +P D+ S EG
Sbjct: 1731 DRFDRERRPRDDRAQSYRDKKDHSSS--------RRGGFDRPSYDRKSDRPVYEGPSMFG 1782
Query: 341 EDME---EDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPL-PPHPHPHPHSVALPPAHL 396
+ E+R L P LSH+P P P L PP P + + L
Sbjct: 1783 GERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGL 1842
Query: 397 P 397
P
Sbjct: 1843 P 1843
Score = 50.8 bits (120), Expect = 3e-06
Identities = 110/557 (19%), Positives = 190/557 (34%), Gaps = 118/557 (21%)
Query: 75 APPPPLATPAPLTVIPIPVV--------TNSPQPLPPPPPLPAAAQPLP--------LAP 118
APPPP A P T + + T Q P P P Q L+
Sbjct: 246 APPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSL 305
Query: 119 RQPALVGAPGLS----IKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL 174
+Q V PG + + P P + +V PA S+ P+ PL P
Sbjct: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPAT----SQVPESPSSEEPPLPP------ 355
Query: 175 TIAPHPGVQPQLAPQQPP---PPTLGTLKLAPAEEVKSSEQKKRPGGI---GTREVHNKL 228
P+ V P L P++P P LK A + ++ G G + H +L
Sbjct: 356 ---PNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQL 412
Query: 229 EKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLARE 288
++ + + ++ + + P++ ++ + ++++++H + RE
Sbjct: 413 QQ-----ILQQYQQIIQPPPHIQTMSVD---------MQLRHYEMQQQQFQHLYQEWERE 458
Query: 289 KIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRA 348
+++L H+ ++ +Q + +T + + + N ++M+
Sbjct: 459 FQLWEEQLHSYPHKD-------QLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYM 511
Query: 349 GLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTP 408
G ++PPP + +PP P P +PP LP P
Sbjct: 512 G---------------NMSMPPPFVPYSQMPP---PLP---TMPPPVLPPSLPPPVMPPA 550
Query: 409 LPAPPPPPAAP-------AQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQG 461
LPA PPP P T VP P + + G + + ++ VL
Sbjct: 551 LPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSA---GPPPVLPP 607
Query: 462 PGGKHIAHIAPSAPSPAVQLAPATPPIG------------HITVHPATLNHVAHLGSQLP 509
P ++ AP P L+ ATPP G +T P + SQ+P
Sbjct: 608 PS---LSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQ-SSQVP 663
Query: 510 ------LYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQVVHHPQLVGQTVL 563
L P PV+ T H + GP V +K + + + L
Sbjct: 664 EKPRPALLPTPVSFGSAPPTTYHPPLQSA---GPSEQVNSKAPLSKSALPYSSFSSDQGL 720
Query: 564 NPVTMVTMPSFPVSTLK 580
+ PS P++ +K
Sbjct: 721 GESS--AAPSQPITAVK 735
Score = 44.3 bits (103), Expect = 3e-04
Identities = 56/215 (26%), Positives = 68/215 (31%), Gaps = 85/215 (39%)
Query: 70 PAPPPAPPPPLATPAPLTVIPIPVVTNS-------------------------------- 97
P PP PPPP+A P P P ++S
Sbjct: 15 PPPPVPPPPPVALP---EASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
Query: 98 -----------PQPLPPPPPLPAAA----QPLP---LAPRQPALV--------------- 124
P PLPPPP +P QP P P PAL
Sbjct: 72 MQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131
Query: 125 --GAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGV 182
G PGL E P P VP P +P S++ +PP P P + P
Sbjct: 132 RDGPPGLVPMELESPPESPPVP-PGSYMPPSQSYMPP----------PQPPPSYYPPTSS 180
Query: 183 QPQLAPQQP----PPPTLGTLKLAPAEEVKSSEQK 213
QP L P QP PP+ L P+ SS +
Sbjct: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQ 215
Score = 43.1 bits (100), Expect = 7e-04
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 359 PQPELLKSTLPPPSTTPAP---LPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPP 415
PQ L++T P P P PP P P + P+ P + P + P+P PPPP
Sbjct: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPP 1550
Query: 416 PAAPAQTLVPAP 427
P P L P P
Sbjct: 1551 PPPP---LPPPP 1559
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/120 (30%), Positives = 52/120 (43%), Gaps = 25/120 (20%)
Query: 53 LPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTN-SPQPLPPPPPLPAAA 111
LP PP L PP+ PPP V+P+P +++ +P P PPP +P
Sbjct: 591 LPPPSLSSAGPPPVLPPPSLSSTAPPP--------VMPLPPLSSATPPPGIPPPGVPQGI 642
Query: 112 QP-LPLAPRQPALVGAPGLSIKEPAPLPSRPQ---VPTPAPLLPDSKATIPPNGSPKPLQ 167
P L AP PA S + + +P +P+ +PTP S + PP PLQ
Sbjct: 643 PPQLTAAPVPPA-------SSSQSSQVPEKPRPALLPTPV-----SFGSAPPTTYHPPLQ 690
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/236 (23%), Positives = 81/236 (34%), Gaps = 59/236 (25%)
Query: 26 EQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPL----------PLSPPAPPPA 75
EQ +L+Q ++ QK+ + + H P P + PP+ P PP PPP
Sbjct: 55 EQHLAQLQQLQQMHQKQMQCVLQPHHLPP---PPLPPPPVMPGGGYGDWQPPPPPMPPPP 111
Query: 76 PP--------------------------------PPLATPAPLTVIPIPVVTNSPQPLPP 103
P PP + P P P + P P PP
Sbjct: 112 GPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPP 171
Query: 104 PPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSP 163
P P + L P QP+ +P S AP PS + + + P+
Sbjct: 172 PSYYPPTSSQPYLPPAQPSPSQSPP-SQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230
Query: 164 KPLQPLPTPVLTIAPHPGVQPQLAPQQP--PPPTLGTLKLAPAE---EVKSSEQKK 214
P +P + LAP P PP T++ P E + KS+EQ++
Sbjct: 231 SPSRP--------SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQ 278
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/76 (36%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 347 RAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQK 406
R G+ PP S+RP P + K PP S PP P V PP +P P
Sbjct: 1502 RPGMYPPPGSYRPPPPMGK---PPGSIVRPSAPPARSSVP--VTRPPVPIPPPPPPP--- 1553
Query: 407 TPLPAPPPPPAAPAQT 422
P PPPPP QT
Sbjct: 1554 ---PLPPPPPVIKPQT 1566
Score = 37.4 bits (85), Expect = 0.038
Identities = 50/199 (25%), Positives = 63/199 (31%), Gaps = 37/199 (18%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPH---PHSVALPP--------------- 393
PP S+ P P+ S PP S+ P P P P P L P
Sbjct: 159 PPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYL 218
Query: 394 ----AHLPVQQQQPQQ------KTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAH 443
++LP Q P + K+ L APPPP A P L + A ST
Sbjct: 219 SHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQ 278
Query: 444 TATTHASVIQTVNHVLQGPGGKHI--------AHIAPSAPSPAVQLAPATPPIGHITVHP 495
A T Q +H+ H+ P V P +TV P
Sbjct: 279 AAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTV-P 337
Query: 496 ATLNHVAHLGSQLPLYPQP 514
AT S+ P P P
Sbjct: 338 ATSQVPESPSSEEPPLPPP 356
Score = 37.0 bits (84), Expect = 0.050
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 16/142 (11%)
Query: 361 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPL--PAPPPPPAA 418
P L+ L P +P P+PP + P +PP P P P PA P P +
Sbjct: 136 PGLVPMELESPPESP-PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
Query: 419 PAQT--LVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPS 476
P L P P++ +++ + ++H+ + S + + QG + AP
Sbjct: 195 PPSQSYLAPTPSY-SSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL-----APP 248
Query: 477 PAVQLAPATPPIGHITVHPATL 498
P P+ PP TV L
Sbjct: 249 P-----PSAPPGNKTTVQQEPL 265
Score = 35.8 bits (81), Expect = 0.11
Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 34/133 (25%)
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPE--LLKSTLPPPSTTPAPL------ 378
+ST+ A+ E+ A L + H+ Q + L LPPP P P+
Sbjct: 38 SSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGY 97
Query: 379 -----PPHPHPHPHSVAL-------------------PPAHLPVQQQQPQQKTPLPAPPP 414
PP P P P AL PP +P++ + P + P+ PP
Sbjct: 98 GDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPV--PPG 155
Query: 415 PPAAPAQTLVPAP 427
P+Q+ +P P
Sbjct: 156 SYMPPSQSYMPPP 168
Score = 32.7 bits (73), Expect = 0.94
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 16/144 (11%)
Query: 96 NSPQPLPPPPPLPAAAQP---------LPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTP 146
+S P PP PP P A P P P+ G + A L Q+
Sbjct: 11 SSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ- 69
Query: 147 APLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP-PTLGTLKLAPAE 205
+ + P+ P P P P PV+ + QP P PPP P L K +
Sbjct: 70 ----KQMQCVLQPHHLPPPPLP-PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYK 124
Query: 206 EVKSSEQKKRPGGIGTREVHNKLE 229
Q+ P G+ E+ + E
Sbjct: 125 HQMLHHQRDGPPGLVPMELESPPE 148
Score = 32.7 bits (73), Expect = 0.94
Identities = 29/104 (27%), Positives = 37/104 (35%), Gaps = 9/104 (8%)
Query: 18 QQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPP 77
+QQQ A E QE++Q + + L+ T LP P A
Sbjct: 275 EQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRT---------KVHLPGHKKGPVVAKD 325
Query: 78 PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQP 121
P +TV V SP PP P P P PL P +P
Sbjct: 326 TPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEP 369
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 68.9 bits (167), Expect = 1e-11
Identities = 100/430 (23%), Positives = 155/430 (36%), Gaps = 57/430 (13%)
Query: 27 QERLRLEQEREQEQKKANSLARLAHTLPVEE--PRMEAPPLPLSPPAPPPAPPPPLATPA 84
+E++R+ +E K + LP +E P + P PPA P PPP A
Sbjct: 10479 EEKVRVPEEPRVPPTK------VPEVLPPKEVVPEKKVPV----PPAKKPEAPPPKVPEA 10528
Query: 85 PLTVIPIPVVTNSPQPLPPPPP---------------LPAAAQPLPLAPRQPALVGAPGL 129
P V+P V P P PP +P A P P +P P + AP
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP-PPEVPEAPKE 10587
Query: 130 SIKE---PAPLPSRPQV------PTPAPLLPDSKATIPPNGSPK-PLQPLPTPVLTIAPH 179
+ E PA P +P+V P ++P+ K +PP P+ P +P P
Sbjct: 10588 VVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE 10647
Query: 180 PGVQPQL--APQQPPP-----PTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNR 232
V + P+ PPP P L+ PAE V+ E P + EK
Sbjct: 10648 KKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE-PAAPPQVTVPPKKPVPEKKA 10706
Query: 233 RAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIAT 292
A + + E +P V + V + ++ K E E+ + +
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766
Query: 293 QQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGP 352
+ + K VLE + P ++A + E+ + EE+ + P
Sbjct: 10767 KPEVPPAKVPEVPKKPVLE-----EKPAVPVPERAESPPPEVYEEPEEIAPEEE---IAP 10818
Query: 353 PKLSHRPQPELLKSTLPPPSTTPAP---LPPHPHPHPHSVALPPAHLPVQQQQPQQKTPL 409
+ P E + +PPP+ P +P P PP P ++ ++
Sbjct: 10819 EEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLK 10878
Query: 410 PAPPPPPAAP 419
P PPPPP AP
Sbjct: 10879 PRPPPPPPAP 10888
Score = 65.1 bits (157), Expect = 2e-10
Identities = 88/423 (20%), Positives = 152/423 (35%), Gaps = 76/423 (17%)
Query: 39 EQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSP 98
E+K +A+ PV+ P + +P P P P A PA + +P VV
Sbjct: 10703 EKKAPAVVAKKPELPPVKVPEVPKEVVP-EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKK 10761
Query: 99 QPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPS----------------RPQ 142
+P P +P A +P P++P L P + + E A P P+
Sbjct: 10762 VAVPKKPEVPPAK--VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPE 10819
Query: 143 VPTPAPLLPDSKATIPPNGSPK------PLQPLPTPVLTIAPHPGV--------QPQLAP 188
P P+ + + +PP P+ P + +P AP P +P+L P
Sbjct: 10820 EEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKP 10879
Query: 189 QQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIP 248
+ PPPP P E+VK I + K + + + E E +P
Sbjct: 10880 RPPPPPPA-----PPKEDVKEK--------IFQLKAIPKKKVPEKPQVPEKVELTPLKVP 10926
Query: 249 NVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMD 308
+ K +R + ++ E + E ++ + R++ ++ E K ++
Sbjct: 10927 GGEKK-----------VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK-----LE 10970
Query: 309 VLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDME--EDRAGLGPPKLSHRPQPELLKS 366
++ V ++ T ++ E I E + E + + P +P+PE
Sbjct: 10971 KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVK 11030
Query: 367 TLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPL--PAPPPPPAAPAQTLV 424
T+ PP P P P P +PV ++ + K P A P P
Sbjct: 11031 TIKPPPVEPEPTP----------IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKT 11080
Query: 425 PAP 427
P+P
Sbjct: 11081 PSP 11083
Score = 63.9 bits (154), Expect = 4e-10
Identities = 98/454 (21%), Positives = 178/454 (39%), Gaps = 65/454 (14%)
Query: 19 QQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPP 78
++ EE+E + E+E E++ + +PV+ P + P+P P P P
Sbjct: 9919 EEYLVEEEEEYIHEEEEFITEEE-------VVPVIPVKVPEVPRKPVP---EEKKPVPVP 9968
Query: 79 PL--ATPAPLTVIP------IPVVTNSPQPLPPPP---------PLPAAAQPLPLAPRQP 121
A PA + +P +PV+ P+ PPP P+P P+P+ P
Sbjct: 9969 KKKEAPPAKVPEVPKKPEEKVPVLI--PKKEKPPPAKVPEVPKKPVPEEKVPVPV----P 10022
Query: 122 ALVGAPGLSIKE--PAPLPSRPQVPTPAP----LLPDSKATIPPNGSPKPLQPLPTPVLT 175
V AP + E P+P + +VP PAP P +P P+ +P P P
Sbjct: 10023 KKVEAPPAKVPEVPKKPVPEK-KVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV 10081
Query: 176 IAPHPGVQPQLAPQQPP------PPTLGTLKLAPAEEVKSSEQKKRP--GGIGTREVHNK 227
AP P V + P P L ++ P EEV E++ P + E
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141
Query: 228 LEKNRRAHLKECFETLKRNIPNVDD--KKTSNLSVLRTALRYIQSLKRKEKEYEHEMERL 285
E+ +E + +P ++ + L ++ + + +K+ + +
Sbjct: 10142 PEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI 10201
Query: 286 AREKIATQQRLAELKHELSQWMDVLEIDR---VLRQTGQPEDDQASTSTASEGEDNIDED 342
+++ A ++ E+ ++ + +L + + T +PE++ S E +I+E
Sbjct: 10202 PKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEV 10261
Query: 343 MEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ 402
E + PP++ PE++K + P + TP P P S +P +PV Q+
Sbjct: 10262 EE-----VAPPRV-----PEVIKKAV-PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQK 10310
Query: 403 PQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGG 436
++ P P P P + ++ V A G
Sbjct: 10311 -KEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKG 10343
Score = 60.5 bits (145), Expect = 4e-09
Identities = 82/386 (21%), Positives = 137/386 (35%), Gaps = 82/386 (21%)
Query: 72 PPPAPPPPLATPAPLTVIPIPVVTNSPQPLP-----PPPPLPAAAQPLPLAPRQPALVGA 126
PPP P PAP V P+P+ P P P P+P +P+P+ ++PA
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA---- 9339
Query: 127 PGLSIKEPAPLPSRPQVPTPAPLLP---DSKATIPPNGSPKPLQPLPT--PVLTIAPHPG 181
P +P P+ P P +P K PP P+ + + T + +
Sbjct: 9340 ------APPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREE 9393
Query: 182 VQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFE 241
P P+ P K P +E + K P
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPA------------------------ 9429
Query: 242 TLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKH 301
K+ +P ++K + V + A + +K E + A QR+ +H
Sbjct: 9430 LPKKPVP--EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH 9487
Query: 302 ELS---QWMDVLEID----RVLRQTGQPEDDQASTSTASEGEDNIDEDMEE------DRA 348
E+S +W E + V R+ + E+++A + E+ + +EE R
Sbjct: 9488 EVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRV 9547
Query: 349 GLGPPKLSHRPQPEL-LKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ--PQQ 405
P +++ R + ++ LK +P P PPA +P ++ P++
Sbjct: 9548 EAEPAEVTERQEKKIVLKPKIPAKIEEP----------------PPAKVPEAPKKIVPEK 9591
Query: 406 KTPLPAPP----PPPAAPAQTLVPAP 427
K P P P PPP P + P P
Sbjct: 9592 KVPAPVPKKEKVPPPKVPEEPKKPVP 9617
Score = 56.2 bits (134), Expect = 8e-08
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 22/198 (11%)
Query: 26 EQERLRLEQEREQEQKKANSLARLAHTLPVEE-PRMEAPPLPLSPPAPPPAPPPPLATPA 84
E++ +L ER+ E K+ L + P EE P++E L P PPPP
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPP----K 10984
Query: 85 PLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVP 144
P+ + +P VT + +P P +P +PL +P P +K P P P+ P
Sbjct: 10985 PVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPK--PKPEAEVKTIKPPPVEPE-P 11041
Query: 145 TP--APLL-----PDSKATIPPNGSPKPLQPLP-TPVLTIAPHPGVQPQLAP----QQPP 192
TP AP+ ++A P + KP P+ P T +P + +L P ++PP
Sbjct: 11042 TPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP 11101
Query: 193 --PPTLGTLKLAPAEEVK 208
P LK P + VK
Sbjct: 11102 DEAPFTYQLKAVPLKFVK 11119
Score = 55.8 bits (133), Expect = 1e-07
Identities = 95/443 (21%), Positives = 151/443 (34%), Gaps = 92/443 (20%)
Query: 3 IETLLEAARFLEWQAQ-QQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM- 60
+E + E F E + ++ E +E ++LEQ R +E+ + + R+ EE +
Sbjct: 10374 VEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVF 10433
Query: 61 EAPPLPLSPPA------PPPAPP----PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA 110
E P P P PP PP P PA + +P +V +P P +P
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493
Query: 111 AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLP 170
P L P++ ++P+ K +PP P+ P
Sbjct: 10494 KVPEVLPPKE----------------------------VVPEKKVPVPPAKKPEA----P 10521
Query: 171 TPVLTIAPHPGVQPQLAPQQPP-----PPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVH 225
P + AP V + P PP PPT P + +KK P I +
Sbjct: 10522 PPKVPEAPKEVVPEKKVPVPPPKKPEVPPTK-----VPEVPKAAVPEKKVPEAIPPKPES 10576
Query: 226 NKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERL 285
E KE ++ +P KK + +K E E E+
Sbjct: 10577 PPPEVPEAP--KEVVP--EKKVPAAPPKKPE-----------VTPVKVPEAPKEVVPEKK 10621
Query: 286 AREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEE 345
+ + K V E+ +V + + +A + E+ EE
Sbjct: 10622 VPVPPPKKPEVPPTK--------VPEVPKVA--VPEKKVPEAIPPKPESPPPEVFEEPEE 10671
Query: 346 DRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVA-----LPPAHLPVQQ 400
P ++ P+P PP T P P P +V LPP +P
Sbjct: 10672 VALEEPPAEVVEEPEPAA------PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP 10725
Query: 401 QQ--PQQKTPLPAPPPPPAAPAQ 421
++ P++K PL P P A PA+
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAK 10748
Score = 55.1 bits (131), Expect = 2e-07
Identities = 100/449 (22%), Positives = 157/449 (34%), Gaps = 70/449 (15%)
Query: 18 QQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEE---PRMEAPPLPLSPPAPPP 74
++++ EE+E L E+E E+++ +P EE P E P + P P P
Sbjct: 10129 EEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEY---VPEEEEFVPEEEVLP-EVKPKVPVP 10184
Query: 75 APPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEP 134
AP P + + IP +P P P + + L + L P +EP
Sbjct: 10185 APVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL---PVEVTEEP 10241
Query: 135 APLP-SRPQVPTPAPLLPDSKATIPPNGSP---KPLQPLPTPVLTIAPHPGVQPQLAPQQ 190
P S ++P P + + + PP K + PTPV P++
Sbjct: 10242 EEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPV--------------PKK 10287
Query: 191 PPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKL-EKNRRAHLKECFETLKRNIPN 249
P K P E+V QKK EV K+ EK KE K
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR--T 10345
Query: 250 VDDKKTSNLSVLRTALRYIQSLKRKEKEYE--------HEMERLARE-KIATQQRLAELK 300
V ++K S ++ L+ E E E HE+E E + + +L+
Sbjct: 10346 VLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLE 10405
Query: 301 -HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRP 359
H + + V ++ RV+ E + A I E + + P K+ R
Sbjct: 10406 QHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKP--PTKVVPRK 10463
Query: 360 QPELLKSTLP-----------------PPSTTPAPLPPHPHPHPHSVALPPAHLPV---- 398
+P +P PP+ P LPP V +PPA P
Sbjct: 10464 EPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPP 10523
Query: 399 ------QQQQPQQKTPLPAPPPPPAAPAQ 421
++ P++K P+P P P P +
Sbjct: 10524 KVPEAPKEVVPEKKVPVPPPKKPEVPPTK 10552
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/435 (21%), Positives = 160/435 (36%), Gaps = 103/435 (23%)
Query: 14 EWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPP 73
+++ ++ EE ++ +ERE E+ + H + EP P+P+ P
Sbjct: 9752 DYKEFEEYEPTEEYDQYEEYEEREYERYEE-------HEEYITEPEK---PIPVKPVPEE 9801
Query: 74 PAPPPPLATPA-------PLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGA 126
P P P A PA P +P+P+ P+ L PPPP P +P V
Sbjct: 9802 PVPTKPKAPPAKVLKKAVPEEKVPVPI----PKKLKPPPPK---------VPEEPKKVFE 9848
Query: 127 PGLSIKEPAPLPSRPQVPTPAPLLP-DSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQ 185
+ I + QV PA +P K + P P + + PV P V +
Sbjct: 9849 EKIRIS--ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV----PEVPKE 9902
Query: 186 LAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKR 245
L P++ +A EEV + ++ + E+ H +E F T +
Sbjct: 9903 LEPEE----------VAFEEEVVTHVEE-----------YLVEEEEEYIHEEEEFITEEE 9941
Query: 246 NIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQ 305
+P + K + + RK E + + ++K A ++ E+ + +
Sbjct: 9942 VVPVIPVK--------------VPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEE 9987
Query: 306 WMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ---PE 362
+ VL P+ ++ + E + + E++ + PK P PE
Sbjct: 9988 KVPVLI----------PKKEKPPPAKVPEVPK---KPVPEEKVPVPVPKKVEAPPAKVPE 10034
Query: 363 LLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ--PQQKTPLPAP-----PPP 415
+ K +P P P P V PPA +P ++ P++K P P P PPP
Sbjct: 10035 VPKKPVPEKKV-PVPA-------PKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP 10086
Query: 416 PAAPAQTLVPAPAHL 430
+ VP P L
Sbjct: 10087 KVPKKREPVPVPVAL 10101
Score = 49.7 bits (117), Expect = 7e-06
Identities = 84/422 (19%), Positives = 155/422 (36%), Gaps = 100/422 (23%)
Query: 12 FLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPA 71
+ E + ++++ A + + E E ++K + +++ P E + + L P
Sbjct: 9509 YREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKI 9568
Query: 72 PPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSI 131
P PP A V +P+ + P +PA P+P + P
Sbjct: 9569 PAKIEEPPPAK-----------VPEAPKKIVPEKKVPA---PVPKKEKVP---------- 9604
Query: 132 KEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPV----LTIAPHPGVQPQLA 187
P +P P+ P P + +PP K +PLP V + I V +
Sbjct: 9605 --PPKVPEEPKKPVP-------EKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVT 9654
Query: 188 PQQPPPPTL---GTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLK 244
++ PP + P E+V + K+ E K+ + R+ +KE E +
Sbjct: 9655 KKEAPPKARVPEEPKRAVPEEKVLKLKPKRE------EEPPAKVTEFRKRVVKE--EKVS 9706
Query: 245 RNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELS 304
P + + +++ ++ KE+ Y E E ++ ++ E ++E
Sbjct: 9707 IEAPKREPQPIKEVTI----------MEEKERAYTLEEEAVSVQR--------EEEYEEY 9748
Query: 305 QWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELL 364
+ D E + +P ++ E E E+ EE + +PE
Sbjct: 9749 EEYDYKEFEEY-----EPTEEYDQYEEYEEREYERYEEHEE-----------YITEPE-- 9790
Query: 365 KSTLPPPSTTPAPLPPHP-HPHPHSVALPPAHLPVQQQQPQQKTPLPAP----PPPPAAP 419
P P+ P P P P PPA + +++ P++K P+P P PPPP P
Sbjct: 9791 ---------KPIPVKPVPEEPVPTKPKAPPAKV-LKKAVPEEKVPVPIPKKLKPPPPKVP 9840
Query: 420 AQ 421
+
Sbjct: 9841 EE 9842
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/290 (21%), Positives = 97/290 (33%), Gaps = 85/290 (29%)
Query: 17 AQQQQRAREEQERLRLEQEREQE--------------QKKANSLARLAHTLPVEEPR--- 59
A +++ A EE++ + + +E E E +K + + P +EP
Sbjct: 10811 APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 60 -MEAPPLPLSPPAPPPAPP----------------------PPLATPAPLTVIPIP---- 92
+E P L PP PPPAPP P + LT + +P
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEK 10930
Query: 93 ---------------------VVTNSPQPLPP-----------PPPLPAAAQPLPLAPRQ 120
V+ P+ P P +P P P+ +
Sbjct: 10931 KVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVE 10990
Query: 121 PALVGAPGLSIKEPAPLPS-RPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPH 179
V I EP +P +P +P PAP P P++P PTP+
Sbjct: 10991 VPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV 11050
Query: 180 PGV-------QPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTR 222
P V P+ +P P G K P+ +++ +K RPG G +
Sbjct: 11051 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS-PIEAERRKLRPGSGGEK 11099
Score = 44.3 bits (103), Expect = 3e-04
Identities = 82/418 (19%), Positives = 152/418 (36%), Gaps = 66/418 (15%)
Query: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPL------- 107
+ + R+ P +P+ A PP PP+ P PIP++ +P+ PPP
Sbjct: 8937 IPDSRVPIPTMPIR--AVPPEEIPPVVAP------PIPLLLPTPEEKKPPPKRIEVTKKA 8988
Query: 108 ------PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNG 161
A+P + PR+ + P + PA P V + A + T
Sbjct: 8989 VKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEV 9048
Query: 162 SPKP-----------------LQPLPTPVLTIAPHPGVQPQLAPQ-QPPPPTLGTLKLAP 203
+ ++ P + P +P P + P +K+
Sbjct: 9049 QKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEA 9108
Query: 204 AEEV---------KSSEQKKRPGGI--GTREVHNKLEKNRRAHL-KECFE-TLKRNIP-N 249
+EV + E +R G G E ++ + KE +E + +R +P
Sbjct: 9109 KKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAK 9168
Query: 250 VDDKKTSNL-SVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMD 308
V +KK V++ + I+ +++ + E E ++ + +++ + + +
Sbjct: 9169 VPEKKAPPPPKVIKKPV--IEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEE 9226
Query: 309 VLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTL 368
V+E+ T + + AS E+ + + E + + + H + K
Sbjct: 9227 VIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIH---VAISKRVE 9283
Query: 369 PPPSTT-----PAPLPPHPHPHPHSVALPPAHLPVQQQQP--QQKTPLPAPPPPPAAP 419
PPP PAP P P P V P +P ++P ++K P+P P PAAP
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/169 (21%), Positives = 71/169 (42%), Gaps = 12/169 (7%)
Query: 270 SLKRKEKEYEHEMER---LAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQ 326
S+ ++EKE E + +++ ++++ + E++ + V E+ + L +PE+
Sbjct: 9854 SITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL----EPEEVA 9909
Query: 327 ASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHP 386
+ E+ + E+ EE+ ++ ++ +P P P P P P
Sbjct: 9910 FEEEVVTHVEEYLVEE-EEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVP 9968
Query: 387 HSVALPPAHLPVQQQQPQQKTPLPAP----PPPPAAPAQTLVPAPAHLV 431
PPA +P ++P++K P+ P PPP P P P V
Sbjct: 9969 KKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKV 10017
Score = 35.8 bits (81), Expect = 0.11
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 10/96 (10%)
Query: 341 EDMEEDRAGLGPPKLSHRPQ---PELLKSTLPPPSTTPAPLPPHPHPHPHSV------AL 391
E + E + + PPK P PE+ K+ +P P +PP P P V +
Sbjct: 10531 EVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV-PEAIPPKPESPPPEVPEAPKEVV 10589
Query: 392 PPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAP 427
P +P + + TP+ P P + VP P
Sbjct: 10590 PEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVP 10625
Score = 34.7 bits (78), Expect = 0.25
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 116 LAPRQPALVGAPGLSI--KEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPV 173
+A + + GA G + K P +P +P+ +P P +KA + SP P++ P+PV
Sbjct: 234 IATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPV 293
Query: 174 LTI-APHPGVQPQLAP 188
+ AP P ++P
Sbjct: 294 RHVRAPTPSPVRSVSP 309
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 20/101 (19%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVAL--------------PPAHLP 397
PPK+ P+ + + +P P PP P + PP +P
Sbjct: 9341 PPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVP 9400
Query: 398 --VQQQQPQQKTPLPAP----PPPPAAPAQTLVPAPAHLVA 432
+++ P+++ P+P PPPP PA P P VA
Sbjct: 9401 EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVA 9441
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 352 PPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPA 411
PPK+ P+ + + +P P +PP P A+P +++ P+ P P
Sbjct: 10522 PPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVP------EKKVPEAIPPKPE 10575
Query: 412 PPPP--PAAPAQTL 423
PPP P AP + +
Sbjct: 10576 SPPPEVPEAPKEVV 10589
Score = 34.3 bits (77), Expect = 0.32
Identities = 47/205 (22%), Positives = 76/205 (37%), Gaps = 26/205 (12%)
Query: 148 PLLPDSKATIPPNGSPKPLQPLPT---PVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPA 204
P +PDS+ IP P++ +P P + P P + P ++PPP + K A
Sbjct: 8935 PDIPDSRVPIPT----MPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVK 8990
Query: 205 EEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTA 264
++ K K P + RE K + P + D + V
Sbjct: 8991 KDAKKVVAK--PKEMTPREEIVKKPPPPTT-------LIPAKAPEIIDVSSKAEEV---- 9037
Query: 265 LRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQP-- 322
I ++ RK KE + E E + +K A + + D LE++ QP
Sbjct: 9038 --KIMTITRK-KEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYY 9094
Query: 323 -EDDQASTSTASEGEDNIDEDMEED 346
E D+ E + + E+ EED
Sbjct: 9095 EEPDEDYEEIKVEAKKEVHEEWEED 9119
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/115 (25%), Positives = 38/115 (33%), Gaps = 35/115 (30%)
Query: 341 EDMEEDRAGLGPPKLSHRPQPELLKSTLP-------PPSTTPAPLPPHPHPHPHSVALPP 393
E + E + PPK +PE+ +P P P P P P P V P
Sbjct: 10587 EVVPEKKVPAAPPK-----KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10641
Query: 394 AHLPVQQQQPQQKTPLPAPPPP-----------------------PAAPAQTLVP 425
+++ P+ P P PPP PAAP Q VP
Sbjct: 10642 KVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVP 10696
Score = 30.0 bits (66), Expect = 6.1
Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 1/66 (1%)
Query: 375 PAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLP-APPPPPAAPAQTLVPAPAHLVAT 433
P PP P P S + P + + Q +Q++P P P P + P+P V+
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSP 309
Query: 434 AGGGST 439
A ST
Sbjct: 310 AARIST 315
Score = 30.0 bits (66), Expect = 6.1
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 139 SRPQVPTPAPLLPDSKATIPPNG--SPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTL 196
S P+V +P P + +A P SP+P P P P + Q P PP
Sbjct: 32662 SPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKIT 32721
Query: 197 GTLKLAPAEEV 207
LK ++E+
Sbjct: 32722 QFLKAEASKEI 32732
Score = 29.6 bits (65), Expect = 8.0
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 14/127 (11%)
Query: 34 QEREQEQKKANSLARLAHTLPVEEPRMEAPPLP-LSPPAPPPAP------PPPLATPAPL 86
Q R +++ +A+ AR T+ + LP +PP PP P PP +A A L
Sbjct: 218 QTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQL 277
Query: 87 TVIPIP-VVTNSPQPL-----PPPPPLPAAAQPLPLAPRQPALVGAPGLSIK-EPAPLPS 139
P + +SP P+ P P P+ + + ++ V +P L K + + + +
Sbjct: 278 ARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVAT 337
Query: 140 RPQVPTP 146
P+VP P
Sbjct: 338 GPEVPPP 344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,958,402
Number of Sequences: 37866
Number of extensions: 2824884
Number of successful extensions: 86807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1225
Number of HSP's successfully gapped in prelim test: 2102
Number of HSP's that attempted gapping in prelim test: 22278
Number of HSP's gapped (non-prelim): 31042
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.