Search of human proteins with 9910392

Search of human proteins with 9910392

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo
sapiens]
         (378 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo ...   785   0.0  
gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo...   501   e-142
gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo ...   501   e-142
gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo sa...   109   5e-24
gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo sa...   109   5e-24
gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo...   100   3e-21
gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo sapi...    46   5e-05
gi|6912430 isoprenylcysteine carboxyl methyltransferase [Homo sa...    29   8.0  
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         29   8.0  

>gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo
           sapiens]
          Length = 378

 Score =  785 bits (2028), Expect = 0.0
 Identities = 378/378 (100%), Positives = 378/378 (100%)

Query: 1   MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 60
           MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ
Sbjct: 1   MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 60

Query: 61  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 120
           LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV
Sbjct: 61  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 120

Query: 121 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 180
           LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF
Sbjct: 121 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 180

Query: 181 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 240
           TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL
Sbjct: 181 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 240

Query: 241 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 300
           LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV
Sbjct: 241 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 300

Query: 301 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 360
           PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE
Sbjct: 301 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 360

Query: 361 IDKGSAYGNSDSKQKLND 378
           IDKGSAYGNSDSKQKLND
Sbjct: 361 IDKGSAYGNSDSKQKLND 378


>gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score =  501 bits (1289), Expect = e-142
 Identities = 232/375 (61%), Positives = 291/375 (77%)

Query: 1   MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 60
           M L   LK+QF+ HL+  +VF+ SGL+IN +QL TL LWP++KQL+R++NCRL+Y + SQ
Sbjct: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60

Query: 61  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 120
           LVMLLEWWS TECT+FTD     ++GKE+A+++LNH FEIDFLCGW++ ERFG+LG SKV
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 180
           LAKKEL YVP+IGW WYF E+VFC RKWE+DR TV   L+ L DYPE  +FL++CEGTRF
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180

Query: 181 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 240
           TE KH +SM+VA AKGLP LK+HLLPRTKGF   V+ LR  V+AVYD TLNFR N+NP+L
Sbjct: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240

Query: 241 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 300
           LG+L GKKY AD+ VRR PLEDIP D+ E + WLHKLYQEKDA QE Y + G FP     
Sbjct: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300

Query: 301 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 360
           P RRPWTL+N+L WA+++L P F F++ +  SGS L + +F+     AS GVR +IGVTE
Sbjct: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360

Query: 361 IDKGSAYGNSDSKQK 375
           I+KGS+YGN + K+K
Sbjct: 361 IEKGSSYGNQEFKKK 375


>gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score =  501 bits (1289), Expect = e-142
 Identities = 232/375 (61%), Positives = 291/375 (77%)

Query: 1   MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 60
           M L   LK+QF+ HL+  +VF+ SGL+IN +QL TL LWP++KQL+R++NCRL+Y + SQ
Sbjct: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60

Query: 61  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 120
           LVMLLEWWS TECT+FTD     ++GKE+A+++LNH FEIDFLCGW++ ERFG+LG SKV
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 180
           LAKKEL YVP+IGW WYF E+VFC RKWE+DR TV   L+ L DYPE  +FL++CEGTRF
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180

Query: 181 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 240
           TE KH +SM+VA AKGLP LK+HLLPRTKGF   V+ LR  V+AVYD TLNFR N+NP+L
Sbjct: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240

Query: 241 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 300
           LG+L GKKY AD+ VRR PLEDIP D+ E + WLHKLYQEKDA QE Y + G FP     
Sbjct: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300

Query: 301 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 360
           P RRPWTL+N+L WA+++L P F F++ +  SGS L + +F+     AS GVR +IGVTE
Sbjct: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360

Query: 361 IDKGSAYGNSDSKQK 375
           I+KGS+YGN + K+K
Sbjct: 361 IEKGSSYGNQEFKKK 375


>gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo
           sapiens]
          Length = 414

 Score =  109 bits (272), Expect = 5e-24
 Identities = 84/318 (26%), Positives = 144/318 (45%), Gaps = 21/318 (6%)

Query: 41  INKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEI 100
           +N   +R IN RL     +  V LLE   G +  I  D  A++    E +++++NH+  +
Sbjct: 72  VNPSWYRWINNRLVATWLTLPVALLETMFGVKVIITGD--AFVP--GERSVIIMNHRTRM 127

Query: 101 DFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQ 160
           D++  W+   R+  L   K+  K  L  VP  GW       +F  RKW+ D+      + 
Sbjct: 128 DWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMID 187

Query: 161 HLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLR- 219
           +  D  E    LI  EGT  TE     S   A   GL + ++ L PRT GF   V  LR 
Sbjct: 188 YFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLRE 247

Query: 220 -NVVSAVYDCTLNFRNNENPTLLGVLNG---KKYHADLYVRRIPLEDIPEDDDECSAWLH 275
              + AV+D T+ + +N   +   +L G   ++ H   +V R P++ +P   ++   W H
Sbjct: 248 GKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIH--FHVHRYPIDTLPTSKEDLQLWCH 305

Query: 276 KLYQEKDAFQEEYY---RTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQ-------F 325
           K ++EK+     +Y   +   F    ++PP +    V  +   S++ +  F        +
Sbjct: 306 KRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFSPAMCLLIY 365

Query: 326 LVSMIRSGSSLTLASFIL 343
           L S+++    +T+  F+L
Sbjct: 366 LYSLVKWYFIITIVIFVL 383


>gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo
           sapiens]
          Length = 376

 Score =  109 bits (272), Expect = 5e-24
 Identities = 84/318 (26%), Positives = 144/318 (45%), Gaps = 21/318 (6%)

Query: 41  INKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEI 100
           +N   +R IN RL     +  V LLE   G +  I  D  A++    E +++++NH+  +
Sbjct: 34  VNPSWYRWINNRLVATWLTLPVALLETMFGVKVIITGD--AFVP--GERSVIIMNHRTRM 89

Query: 101 DFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQ 160
           D++  W+   R+  L   K+  K  L  VP  GW       +F  RKW+ D+      + 
Sbjct: 90  DWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMID 149

Query: 161 HLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLR- 219
           +  D  E    LI  EGT  TE     S   A   GL + ++ L PRT GF   V  LR 
Sbjct: 150 YFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLRE 209

Query: 220 -NVVSAVYDCTLNFRNNENPTLLGVLNG---KKYHADLYVRRIPLEDIPEDDDECSAWLH 275
              + AV+D T+ + +N   +   +L G   ++ H   +V R P++ +P   ++   W H
Sbjct: 210 GKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIH--FHVHRYPIDTLPTSKEDLQLWCH 267

Query: 276 KLYQEKDAFQEEYY---RTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQ-------F 325
           K ++EK+     +Y   +   F    ++PP +    V  +   S++ +  F        +
Sbjct: 268 KRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFSPAMCLLIY 327

Query: 326 LVSMIRSGSSLTLASFIL 343
           L S+++    +T+  F+L
Sbjct: 328 LYSLVKWYFIITIVIFVL 345


>gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo
           sapiens]
          Length = 364

 Score =  100 bits (248), Expect = 3e-21
 Identities = 66/259 (25%), Positives = 128/259 (49%), Gaps = 16/259 (6%)

Query: 44  QLFRKINCRLSYCISSQLVMLL-EWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDF 102
           + ++ ++ RL YC+   +V+   E ++G +  ++ D    L   KEN I + NH+  +D+
Sbjct: 45  RFYQALDDRL-YCVYQSMVLFFFENYTGVQILLYGD----LPKNKENIIYLANHQSTVDW 99

Query: 103 LCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHL 162
           +    L+ R   LG  + + K+ L ++P+ G  +     ++  R  + + K +   LQ  
Sbjct: 100 IVADILAIRQNALGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSY 159

Query: 163 RDYPEKYFFLIHCEGTRFTEKKHEI---SMQVARAKGLPRLKHHLLPRTKGFAITVRSLR 219
            D     + +I  EGTR+  ++ ++   S   A  +GL  LKH L PR K   +    ++
Sbjct: 160 VDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMK 219

Query: 220 NVVSAVYDCTLNF-------RNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSA 272
           N + A+YD T+ +       +  E+PT+   L  +     +++ RI  +D+PE+ +    
Sbjct: 220 NYLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRR 279

Query: 273 WLHKLYQEKDAFQEEYYRT 291
           WLH+ ++ KD    E+Y +
Sbjct: 280 WLHERFEIKDKMLIEFYES 298


>gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo
           sapiens]
          Length = 370

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 25/159 (15%)

Query: 180 FTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSL----RNVVSA----------- 224
           F  K+ E S   A+   LP L +  LPR+    I + +L    +N   A           
Sbjct: 187 FLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKS 246

Query: 225 -----VYDCTLNFRNNENPTLLGVLNG--KKYHADLYVRRIPLEDIPEDDDECSAWLHKL 277
                + D T+ +   E   +   + G  K     ++ R  P++D+P + D+ + WL++ 
Sbjct: 247 KGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLTTWLYQR 306

Query: 278 YQEKDAFQEEYYRTGTFPETP--MVPPRRPWTLVN-WLF 313
           + EK+     +Y TG FP +        R  TL N W+F
Sbjct: 307 FVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIF 345


>gi|6912430 isoprenylcysteine carboxyl methyltransferase [Homo
           sapiens]
          Length = 284

 Score = 28.9 bits (63), Expect = 8.0
 Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 306 WTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFIL 343
           W+   W +  SL L+ + ++LV+ + +  SL+L SF+L
Sbjct: 90  WSHFGW-YMCSLSLFHYSEYLVTAVNNPKSLSLDSFLL 126


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 28.9 bits (63), Expect = 8.0
 Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 2/37 (5%)

Query: 11  FLCHLVFCYVFIASGLIINTIQLFTLL--LWPINKQL 45
           F+ H+VF   F  +G IIN I ++ ++  LWP+ + L
Sbjct: 599 FIFHIVFSEEFEYTGQIINLIYIYPMIIHLWPMARGL 635


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,340,489
Number of Sequences: 37866
Number of extensions: 642977
Number of successful extensions: 1697
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1685
Number of HSP's gapped (non-prelim): 10
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.