Guide to the Human Genome
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Name: CFTR Sequence: fasta or formatted (1480aa) NCBI GI: 90421313
Description:

cystic fibrosis transmembrane conductance regulator

Referenced in:

ATP-binding Cassette Proteins
Chloride Channels
Major Disease Loci
Polymorphism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         83           2
 C cysteine            1.2         18           1
 D aspartate           3.9         58           2
 E glutamate           6.3         93           3
 F phenylalanine       5.7         85           3
 G glycine             5.7         84           2
 H histidine           1.7         25           2
 I isoleucine          8.0        119           2
 K lysine              6.2         92           2
 L leucine            12.4        183           3
 M methionine          2.5         37           3
 N asparagine          3.6         54           4
 P proline             3.0         45           1
 Q glutamine           4.5         67           2
 R arginine            5.3         78           3
 S serine              8.3        123           2
 T threonine           5.6         83           3
 V valine              6.1         90           2
 W tryptophan          1.6         23           1
 Y tyrosine            2.7         40           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cystic fibrosis transmembrane conductance regulator ... 
ABCC4                 0.135   ATP-binding cassette, sub-family C, member 4 isofor...
ABCC4                 0.135   ATP-binding cassette, sub-family C, member 4 isofor...
ABCC5                 0.095   ATP-binding cassette, sub-family C, member 5 isoform...
ABCC9                 0.091   ATP-binding cassette, sub-family C, member 9 isofor...
ABCC9                 0.090   ATP-binding cassette, sub-family C, member 9 isofor...
ABCC9                 0.090   ATP-binding cassette, sub-family C, member 9 isofor...
ABCC8                 0.090   ATP-binding cassette, sub-family C, member 8 
ABCC12                0.088   ATP-binding cassette protein C12 
ABCC2                 0.088   ATP-binding cassette, sub-family C (CFTR/MRP), member...
ABCC11                0.088   ATP-binding cassette, sub-family C, member 11 isofor...
ABCC11                0.088   ATP-binding cassette, sub-family C, member 11 isofor...
ABCC3                 0.088   ATP-binding cassette, sub-family C, member 3 isoform ...
ABCC1                 0.087   ATP-binding cassette, sub-family C, member 1 isofor...
ABCC1                 0.087   ATP-binding cassette, sub-family C, member 1 isofor...
ABCC1                 0.087   ATP-binding cassette, sub-family C, member 1 isofor...
ABCC1                 0.087   ATP-binding cassette, sub-family C, member 1 isofor...
ABCC10                0.084   ATP-binding cassette, sub-family C, member 10 
ABCC1                 0.081   ATP-binding cassette, sub-family C, member 1 isofor...
ABCC6                 0.079   ATP-binding cassette, sub-family C, member 6 isofor...
LOC100292715          0.079   PREDICTED: hypothetical protein 
ABCC11                0.078   ATP-binding cassette, sub-family C, member 11 isofor...
ABCC3                 0.032   ATP-binding cassette, sub-family C, member 3 isofor...
ABCB8                 0.031   ATP-binding cassette, sub-family B, member 8 
ABCB7                 0.031   ATP-binding cassette, sub-family B, member 7 
ABCB1                 0.030   ATP-binding cassette, subfamily B, member 1 
ABCB6                 0.029   ATP-binding cassette, sub-family B, member 6 
ABCB5                 0.028   ATP-binding cassette, sub-family B, member 5 
ABCB10                0.028   ATP-binding cassette, sub-family B, member 10 [Homo...
ABCB4                 0.028   ATP-binding cassette, subfamily B, member 4 isoform B...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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