Guide to the Human Genome
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Search of human proteins with 7706103

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706103 relaxin/insulin-like family peptide receptor 3 [Homo
sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706103 relaxin/insulin-like family peptide receptor 3 [Homo ...   950   0.0  
gi|32490567 relaxin 3 receptor 2 [Homo sapiens]                       257   2e-68
gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]            161   1e-39
gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]            161   1e-39
gi|14043062 angiotensin II receptor, type 1 [Homo sapiens]            161   1e-39
gi|6715583 angiotensin II receptor, type 1 [Homo sapiens]             161   1e-39
gi|4501997 angiotensin II receptor, type 1 [Homo sapiens]             161   1e-39
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     157   3e-38
gi|4557861 somatostatin receptor 3 [Homo sapiens]                     157   3e-38
gi|4557859 somatostatin receptor 2 [Homo sapiens]                     155   7e-38
gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]            150   2e-36
gi|4557857 somatostatin receptor 1 [Homo sapiens]                     149   4e-36
gi|4885057 apelin receptor [Homo sapiens]                             147   2e-35
gi|148228829 G protein-coupled receptor 1 [Homo sapiens]              146   3e-35
gi|36951012 G protein-coupled receptor 1 [Homo sapiens]               146   3e-35
gi|53828924 G protein-coupled receptor 7 [Homo sapiens]               146   5e-35
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                   143   3e-34
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]      142   5e-34
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   141   1e-33
gi|4505513 opiate receptor-like 1 [Homo sapiens]                      141   1e-33
gi|33286424 opiate receptor-like 1 [Homo sapiens]                     141   1e-33
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]      139   7e-33
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]       139   7e-33
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]     137   3e-32
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]     137   3e-32
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]     137   3e-32
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]     137   3e-32
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]      137   3e-32
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]     137   3e-32
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]      137   3e-32

>gi|7706103 relaxin/insulin-like family peptide receptor 3 [Homo
           sapiens]
          Length = 469

 Score =  950 bits (2455), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA 60
           MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA
Sbjct: 1   MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA 60

Query: 61  PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF 120
           PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF
Sbjct: 61  PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF 120

Query: 121 VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR 180
           VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR
Sbjct: 121 VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR 180

Query: 181 YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK 240
           YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK
Sbjct: 181 YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK 240

Query: 241 VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA 300
           VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA
Sbjct: 241 VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA 300

Query: 301 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS 360
           GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS
Sbjct: 301 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS 360

Query: 361 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA 420
           QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA
Sbjct: 361 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA 420

Query: 421 TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY 469
           TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
Sbjct: 421 TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY 469


>gi|32490567 relaxin 3 receptor 2 [Homo sapiens]
          Length = 374

 Score =  257 bits (656), Expect = 2e-68
 Identities = 141/322 (43%), Positives = 194/322 (60%), Gaps = 40/322 (12%)

Query: 80  VRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSS-INLFVTNLALTDFQFVLTLPFW 138
           +R+++++ Y +V A+GL GNL VL+++ +          + FV NLAL D    LTLPFW
Sbjct: 38  LRLMVALAYGLVGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFW 97

Query: 139 AVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGR 198
           A E+ALDF WPFG A+CK+V   T +N+YAS+F +TA+SV RY  VA A           
Sbjct: 98  AAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAA---------- 147

Query: 199 GDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGR 258
           G     SL     F A+   + +WA AAL ++P+A+F    +V G  LCL+RFP +    
Sbjct: 148 GPGTHLSL-----FWARIATLAVWAAAALVTVPTAVFGVEGEVCGVRLCLLRFPSR---- 198

Query: 259 DRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASA 318
              +WLG Y  Q+V+L F++PLG+I   YLLL+ F+  RR    +    VA         
Sbjct: 199 ---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFL-QRRQRRRQDSRVVA--------- 245

Query: 319 RRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLA 378
                  +SV I+V SFFLCW PN  +T W +L+KF+ VP++  ++  Q Y FPV+ CLA
Sbjct: 246 -------RSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLA 298

Query: 379 HSNSCLNPVLYCLVRREFRKAL 400
           HSNSCLNPVLYCL+RRE R+AL
Sbjct: 299 HSNSCLNPVLYCLLRREPRQAL 320


>gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score =  161 bits (408), Expect = 1e-39
 Identities = 108/360 (30%), Positives = 176/360 (48%), Gaps = 39/360 (10%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           ++I  +Y ++  +G+ GN LV+ ++       K+  ++F+ NLAL D  F+LTLP WAV 
Sbjct: 29  VMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL-KTVASVFLLNLALADLCFLLTLPLWAVY 87

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
            A++++WPFG  +CKI S   S N+YASVF LT +S+ RY ++   +KS   R       
Sbjct: 88  TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRR------- 140

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
                       AK  C+ IW LA LASLP+ I      +    + +  F  +       
Sbjct: 141 --------TMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLP 192

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
             LGL    K +LGF+ P  II+  Y L+ + +        K    +   +P      R 
Sbjct: 193 IGLGL---TKNILGFLFPFLIILTSYTLIWKAL--------KKAYEIQKNKP------RN 235

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
             + K +  +VL FF  W+P+Q  T   +LI+   +   +   +    A P+++C+A+ N
Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDT-AMPITICIAYFN 294

Query: 382 SCLNPVLYCLVRREFRKALKSLLWRI----ASPSITSMRPFTATTKP-EHEDQGLQAPAP 436
           +CLNP+ Y  + ++F++    LL  I     S S  S +  T + +P ++     + PAP
Sbjct: 295 NCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAP 354


>gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score =  161 bits (408), Expect = 1e-39
 Identities = 108/360 (30%), Positives = 176/360 (48%), Gaps = 39/360 (10%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           ++I  +Y ++  +G+ GN LV+ ++       K+  ++F+ NLAL D  F+LTLP WAV 
Sbjct: 29  VMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL-KTVASVFLLNLALADLCFLLTLPLWAVY 87

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
            A++++WPFG  +CKI S   S N+YASVF LT +S+ RY ++   +KS   R       
Sbjct: 88  TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRR------- 140

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
                       AK  C+ IW LA LASLP+ I      +    + +  F  +       
Sbjct: 141 --------TMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLP 192

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
             LGL    K +LGF+ P  II+  Y L+ + +        K    +   +P      R 
Sbjct: 193 IGLGL---TKNILGFLFPFLIILTSYTLIWKAL--------KKAYEIQKNKP------RN 235

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
             + K +  +VL FF  W+P+Q  T   +LI+   +   +   +    A P+++C+A+ N
Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDT-AMPITICIAYFN 294

Query: 382 SCLNPVLYCLVRREFRKALKSLLWRI----ASPSITSMRPFTATTKP-EHEDQGLQAPAP 436
           +CLNP+ Y  + ++F++    LL  I     S S  S +  T + +P ++     + PAP
Sbjct: 295 NCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAP 354


>gi|14043062 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score =  161 bits (408), Expect = 1e-39
 Identities = 108/360 (30%), Positives = 176/360 (48%), Gaps = 39/360 (10%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           ++I  +Y ++  +G+ GN LV+ ++       K+  ++F+ NLAL D  F+LTLP WAV 
Sbjct: 29  VMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL-KTVASVFLLNLALADLCFLLTLPLWAVY 87

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
            A++++WPFG  +CKI S   S N+YASVF LT +S+ RY ++   +KS   R       
Sbjct: 88  TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRR------- 140

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
                       AK  C+ IW LA LASLP+ I      +    + +  F  +       
Sbjct: 141 --------TMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLP 192

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
             LGL    K +LGF+ P  II+  Y L+ + +        K    +   +P      R 
Sbjct: 193 IGLGL---TKNILGFLFPFLIILTSYTLIWKAL--------KKAYEIQKNKP------RN 235

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
             + K +  +VL FF  W+P+Q  T   +LI+   +   +   +    A P+++C+A+ N
Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDT-AMPITICIAYFN 294

Query: 382 SCLNPVLYCLVRREFRKALKSLLWRI----ASPSITSMRPFTATTKP-EHEDQGLQAPAP 436
           +CLNP+ Y  + ++F++    LL  I     S S  S +  T + +P ++     + PAP
Sbjct: 295 NCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAP 354


>gi|6715583 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score =  161 bits (408), Expect = 1e-39
 Identities = 108/360 (30%), Positives = 176/360 (48%), Gaps = 39/360 (10%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           ++I  +Y ++  +G+ GN LV+ ++       K+  ++F+ NLAL D  F+LTLP WAV 
Sbjct: 29  VMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL-KTVASVFLLNLALADLCFLLTLPLWAVY 87

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
            A++++WPFG  +CKI S   S N+YASVF LT +S+ RY ++   +KS   R       
Sbjct: 88  TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRR------- 140

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
                       AK  C+ IW LA LASLP+ I      +    + +  F  +       
Sbjct: 141 --------TMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLP 192

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
             LGL    K +LGF+ P  II+  Y L+ + +        K    +   +P      R 
Sbjct: 193 IGLGL---TKNILGFLFPFLIILTSYTLIWKAL--------KKAYEIQKNKP------RN 235

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
             + K +  +VL FF  W+P+Q  T   +LI+   +   +   +    A P+++C+A+ N
Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDT-AMPITICIAYFN 294

Query: 382 SCLNPVLYCLVRREFRKALKSLLWRI----ASPSITSMRPFTATTKP-EHEDQGLQAPAP 436
           +CLNP+ Y  + ++F++    LL  I     S S  S +  T + +P ++     + PAP
Sbjct: 295 NCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAP 354


>gi|4501997 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score =  161 bits (408), Expect = 1e-39
 Identities = 108/360 (30%), Positives = 176/360 (48%), Gaps = 39/360 (10%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           ++I  +Y ++  +G+ GN LV+ ++       K+  ++F+ NLAL D  F+LTLP WAV 
Sbjct: 29  VMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL-KTVASVFLLNLALADLCFLLTLPLWAVY 87

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
            A++++WPFG  +CKI S   S N+YASVF LT +S+ RY ++   +KS   R       
Sbjct: 88  TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRR------- 140

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
                       AK  C+ IW LA LASLP+ I      +    + +  F  +       
Sbjct: 141 --------TMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLP 192

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
             LGL    K +LGF+ P  II+  Y L+ + +        K    +   +P      R 
Sbjct: 193 IGLGL---TKNILGFLFPFLIILTSYTLIWKAL--------KKAYEIQKNKP------RN 235

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
             + K +  +VL FF  W+P+Q  T   +LI+   +   +   +    A P+++C+A+ N
Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDT-AMPITICIAYFN 294

Query: 382 SCLNPVLYCLVRREFRKALKSLLWRI----ASPSITSMRPFTATTKP-EHEDQGLQAPAP 436
           +CLNP+ Y  + ++F++    LL  I     S S  S +  T + +P ++     + PAP
Sbjct: 295 NCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAP 354


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score =  157 bits (396), Expect = 3e-38
 Identities = 126/379 (33%), Positives = 181/379 (47%), Gaps = 51/379 (13%)

Query: 69  GGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTD 128
           G A SA   A   +L+ V+Y +VCA GL GN LV+Y++       K+  N+++ NLA+ D
Sbjct: 31  GPAPSAGARA---VLVPVLYLLVCAAGLGGNTLVIYVVLRFAKM-KTVTNIYILNLAVAD 86

Query: 129 FQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASAL 188
             ++L LPF A +NA  F WPFG  +C++V  +  +N + SVF LT MSV RY +V   L
Sbjct: 87  VLYMLGLPFLATQNAASF-WPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPL 145

Query: 189 KSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCL 248
            S R R                   AK      W L+   SLP  +F+    V     C 
Sbjct: 146 SSARWRRPR---------------VAKLASAAAWVLSLCMSLPLLVFA---DVQEGGTCN 187

Query: 249 VRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAV 308
             +P+ +       W  ++     +LGF  PL +I LCYLL+V  +   RAAG + G   
Sbjct: 188 ASWPEPV-----GLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKV---RAAGVRVGC-- 237

Query: 309 AGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQV 368
                     R   KVT+ V +VVL F  CWLP      +++ I   AV   QE     +
Sbjct: 238 -------VRRRSERKVTRMVLVVVLVFAGCWLP-----FFTVNIVNLAVALPQEPASAGL 285

Query: 369 YAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTAT-TKPEHE 427
           Y F   V L+++NSC NPVLY  +   FR++ + +L        +  +   AT  +P+  
Sbjct: 286 YFF--VVILSYANSCANPVLYGFLSDNFRQSFQKVL---CLRKGSGAKDADATEPRPDRI 340

Query: 428 DQGLQAPAPPHAAAEPDLL 446
            Q  +A  P H AA   L+
Sbjct: 341 RQQQEATPPAHRAAANGLM 359


>gi|4557861 somatostatin receptor 3 [Homo sapiens]
          Length = 418

 Score =  157 bits (396), Expect = 3e-38
 Identities = 122/380 (32%), Positives = 179/380 (47%), Gaps = 48/380 (12%)

Query: 57  PDGAPPGHPPGS--GGAESADTEARVRI---LISVVYWVVCALGLAGNLLVLYLMKSMQG 111
           P+ A    PP +  G   +  + A + +   LI +VY VVC +GL GN LV+Y++     
Sbjct: 15  PENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA 74

Query: 112 WRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVF 171
              S  N+++ NLAL D  F+L LPF A +NAL + WPFG  MC++V  V  +N + S+F
Sbjct: 75  -SPSVTNVYILNLALADELFMLGLPFLAAQNALSY-WPFGSLMCRLVMAVDGINQFTSIF 132

Query: 172 FLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLP 231
            LT MSV RY +V    +S R R                   A+ +   +W  +A+  LP
Sbjct: 133 CLTVMSVDRYLAVVHPTRSARWR---------------TAPVARTVSAAVWVASAVVVLP 177

Query: 232 SAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLV 291
             +FS   +  G   C +++P+         W   +      LGF  PL +I LCYLL+V
Sbjct: 178 VVVFSGVPR--GMSTCHMQWPEPAAA-----WRAGFIIYTAALGFFGPLLVICLCYLLIV 230

Query: 292 RFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSIL 351
             +   R+AG +  A     R      R   +VT+ V  VV  F LCW+P   L   +++
Sbjct: 231 VKV---RSAGRRVWAPSCQRR-----RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVV 282

Query: 352 IKFNAVP-FSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASP 410
                 P F   YFL         V L ++NSC NP+LY  +   F++  + +L R  S 
Sbjct: 283 CPLPEEPAFFGLYFLV--------VALPYANSCANPILYGFLSYRFKQGFRRVLLR-PSR 333

Query: 411 SITSMRPFTA-TTKPEHEDQ 429
            + S  P      K E ED+
Sbjct: 334 RVRSQEPTVGPPEKTEEEDE 353


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score =  155 bits (392), Expect = 7e-38
 Identities = 101/325 (31%), Positives = 164/325 (50%), Gaps = 45/325 (13%)

Query: 83  LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVEN 142
           +++ +Y+VVC +GL GN LV+Y++       K+  N+++ NLA+ D  F+L LPF A++ 
Sbjct: 45  VLTFIYFVVCIIGLCGNTLVIYVILRYAKM-KTITNIYILNLAIADELFMLGLPFLAMQV 103

Query: 143 ALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCC 202
           AL   WPFGKA+C++V  V  +N + S+F LT MS+ RY +V   +KS + R        
Sbjct: 104 AL-VHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPR----- 157

Query: 203 GRSLGDSCCFSAKALCVWIWALAALASLPSAIFS-TTVKVMGEELCLVRFPDKLLGRDRQ 261
                     +AK + + +W ++ L  LP  I++       G   C + +P      +  
Sbjct: 158 ----------TAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPG-----ESG 202

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
            W   +     +LGF++PL II LCYL ++  +              + G   G+S R+ 
Sbjct: 203 AWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVK-------------SSGIRVGSSKRKK 249

Query: 322 S--KVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAH 379
           S  KVT+ V+IVV  F  CWLP       S+ +  +  P  +         F   V L +
Sbjct: 250 SEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKG-------MFDFVVVLTY 302

Query: 380 SNSCLNPVLYCLVRREFRKALKSLL 404
           +NSC NP+LY  +   F+K+ +++L
Sbjct: 303 ANSCANPILYAFLSDNFKKSFQNVL 327


>gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]
          Length = 363

 Score =  150 bits (379), Expect = 2e-36
 Identities = 94/322 (29%), Positives = 152/322 (47%), Gaps = 38/322 (11%)

Query: 84  ISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENA 143
           I ++Y+++  +G   N++V+ L    +G +K S ++++ NLA+ D   + TLP WA   +
Sbjct: 47  IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVS-SIYIFNLAVADLLLLATLPLWATYYS 105

Query: 144 LDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCG 203
             + W FG  MCK+     ++NM+AS+FF+T MSV RY SV     S R           
Sbjct: 106 YRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNP-------- 157

Query: 204 RSLGDSCCFSAKALCVWIWALAALASLPSAIFS--TTVKVMGEELCLVRFPDKLLGRDRQ 261
                   + A  +   +W +A L+SLP+  F    T++ +G   C++ FP +   +   
Sbjct: 158 --------WQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQ--- 206

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL 321
            W       K +LGF++PL  I  CY  + + +    +               G +    
Sbjct: 207 -WSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNS--------------YGKNRITR 251

Query: 322 SKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSN 381
            +V K    VVL+F +CWLP   LT    L     +  S E       A P ++ L  +N
Sbjct: 252 DQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIN-SCEVIAVIDLALPFAILLGFTN 310

Query: 382 SCLNPVLYCLVRREFRKALKSL 403
           SC+NP LYC V   F++ L+S+
Sbjct: 311 SCVNPFLYCFVGNRFQQKLRSV 332


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score =  149 bits (377), Expect = 4e-36
 Identities = 108/353 (30%), Positives = 173/353 (49%), Gaps = 58/353 (16%)

Query: 66  PGSGGAESADTEAR-------------VRILISVVYWVVCALGLAGNLLVLYLMKSMQGW 112
           PG+G A+  +   R               ILIS +Y VVC +GL GN +V+Y++      
Sbjct: 30  PGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKM 89

Query: 113 RKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFF 172
            K++ N+++ NLA+ D   +L++PF  V + L   WPFG  +C++V  V ++NM+ S++ 
Sbjct: 90  -KTATNIYILNLAIADELLMLSVPF-LVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYC 147

Query: 173 LTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPS 232
           LT +SV RY +V   +K+ R R                   AK + + +W L+ L  LP 
Sbjct: 148 LTVLSVDRYVAVVHPIKAARYRRP---------------TVAKVVNLGVWVLSLLVILPI 192

Query: 233 AIFS-TTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLV 291
            +FS T     G   C +  P+       Q WL  +     L+GF+LP+G I LCY+L+ 
Sbjct: 193 VVFSRTAANSDGTVACNMLMPE-----PAQRWLVGFVLYTFLMGFLLPVGAICLCYVLI- 246

Query: 292 RFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSIL 351
             IA  R    K     AG +    S R   K+T  V +VV+ F +CW+P   +   ++ 
Sbjct: 247 --IAKMRMVALK-----AGWQQRKRSER---KITLMVMMVVMVFVICWMPFYVVQLVNVF 296

Query: 352 IKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLL 404
            + +    SQ           +SV L ++NSC NP+LY  +   F+++ + +L
Sbjct: 297 AEQDDATVSQ-----------LSVILGYANSCANPILYGFLSDNFKRSFQRIL 338


>gi|4885057 apelin receptor [Homo sapiens]
          Length = 380

 Score =  147 bits (371), Expect = 2e-35
 Identities = 107/361 (29%), Positives = 165/361 (45%), Gaps = 41/361 (11%)

Query: 83  LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVEN 142
           LI  +Y +V  LG  GN LVL+ +      ++ S ++F+ +LA+ D  FV+TLP WA   
Sbjct: 30  LIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYT 89

Query: 143 ALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCC 202
             D+ WPFG   CK+ S +  +NMYASVF LT +S  RY ++   + + R R    G   
Sbjct: 90  YRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSG--- 146

Query: 203 GRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTT--VKVMGEELCLVRFPDKLLGRDR 260
                      A A  V +W LAAL ++P  +  TT  ++   +  C + +         
Sbjct: 147 -----------AVATAV-LWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSE 194

Query: 261 QFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADR-RAAGTKGGAAVAGGRPTGASAR 319
             W          +GFV+P  I++ CY  + + IA   R    +G              R
Sbjct: 195 WAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEG-------------LR 241

Query: 320 RLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAH 379
           +  ++   + ++V++F LCW+P   + T  +L      P   + FL  +  FP   C+++
Sbjct: 242 KRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNI--FPYCTCISY 299

Query: 380 SNSCLNPVLYCLVRREFRKALKSLLW----RIASPSITSMRPFTATTKPEHEDQGLQAPA 435
            NSCLNP LY      FR+A  S+L     R A  S +S    +A+    H     Q P 
Sbjct: 300 VNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHS----QGPG 355

Query: 436 P 436
           P
Sbjct: 356 P 356


>gi|148228829 G protein-coupled receptor 1 [Homo sapiens]
          Length = 355

 Score =  146 bits (369), Expect = 3e-35
 Identities = 108/371 (29%), Positives = 173/371 (46%), Gaps = 67/371 (18%)

Query: 73  SADTEARVRILISVVYWV-------VCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLA 125
           S +++   ++ + VV+WV          LG+ GN +V++       W+K+   L+  NLA
Sbjct: 23  SLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFK--WKKTVTTLWFLNLA 80

Query: 126 LTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVA 185
           + DF F+L LP +    A++F WPFG  +CK  S    +NM+ASVFFLT +S+  Y  + 
Sbjct: 81  IADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLI 140

Query: 186 SALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEE 245
             + SHR           R+L +S       + ++IW LA+L   P+  F  TV+     
Sbjct: 141 HPVLSHR----------HRTLKNSL-----IVIIFIWLLASLIGGPALYFRDTVEFNNHT 185

Query: 246 LCLVRF----PDKLLGRDRQF-WLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA 300
           LC   F    PD  L R     W+      K ++G++ PL  + +CYL L+  +  R   
Sbjct: 186 LCYNNFQKHDPDLTLIRHHVLTWV------KFIIGYLFPLLTMSICYLCLIFKVKKR--- 236

Query: 301 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS 360
                           S    S+   ++ +VV++F +CW P    + W + I  N    S
Sbjct: 237 ----------------SILISSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHN----S 276

Query: 361 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFR--------KALKSLLWRIASPSI 412
             + + Q    P+S  LA  NSCLNP+LY L+ ++F+        + LK  LW ++    
Sbjct: 277 YSHHVMQA-GIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEILKYTLWEVSCSGT 335

Query: 413 TSMRPFTATTK 423
            S +   + TK
Sbjct: 336 VSEQLRNSETK 346


>gi|36951012 G protein-coupled receptor 1 [Homo sapiens]
          Length = 355

 Score =  146 bits (369), Expect = 3e-35
 Identities = 108/371 (29%), Positives = 173/371 (46%), Gaps = 67/371 (18%)

Query: 73  SADTEARVRILISVVYWV-------VCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLA 125
           S +++   ++ + VV+WV          LG+ GN +V++       W+K+   L+  NLA
Sbjct: 23  SLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFK--WKKTVTTLWFLNLA 80

Query: 126 LTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVA 185
           + DF F+L LP +    A++F WPFG  +CK  S    +NM+ASVFFLT +S+  Y  + 
Sbjct: 81  IADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLI 140

Query: 186 SALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEE 245
             + SHR           R+L +S       + ++IW LA+L   P+  F  TV+     
Sbjct: 141 HPVLSHR----------HRTLKNSL-----IVIIFIWLLASLIGGPALYFRDTVEFNNHT 185

Query: 246 LCLVRF----PDKLLGRDRQF-WLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA 300
           LC   F    PD  L R     W+      K ++G++ PL  + +CYL L+  +  R   
Sbjct: 186 LCYNNFQKHDPDLTLIRHHVLTWV------KFIIGYLFPLLTMSICYLCLIFKVKKR--- 236

Query: 301 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS 360
                           S    S+   ++ +VV++F +CW P    + W + I  N    S
Sbjct: 237 ----------------SILISSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHN----S 276

Query: 361 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFR--------KALKSLLWRIASPSI 412
             + + Q    P+S  LA  NSCLNP+LY L+ ++F+        + LK  LW ++    
Sbjct: 277 YSHHVMQA-GIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEILKYTLWEVSCSGT 335

Query: 413 TSMRPFTATTK 423
            S +   + TK
Sbjct: 336 VSEQLRNSETK 346


>gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
          Length = 328

 Score =  146 bits (368), Expect = 5e-35
 Identities = 112/371 (30%), Positives = 165/371 (44%), Gaps = 57/371 (15%)

Query: 40  NASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGN 99
           NAS   P   W      PD A       S  +  A   A + + + VVY V+CA+GLAGN
Sbjct: 3   NASFSEP---WPANASGPDPALSC----SNASTLAPLPAPLAVAVPVVYAVICAVGLAGN 55

Query: 100 LLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDF---KWPFGKAMCK 156
             VLY++       K+  NLF+ NLA+ D  F L LP     N  DF   +WPFG+ MCK
Sbjct: 56  SAVLYVLLRAPRM-KTVTNLFILNLAIADELFTLVLPI----NIADFLLRQWPFGELMCK 110

Query: 157 IVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKA 216
           ++  +   N ++S++FLT MS  RY  V +  +S R  G                 +A+A
Sbjct: 111 LIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYS-------------AARA 157

Query: 217 LCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGF 276
           + + +W +  L  LP A+F+      G   C++ FP     +   FW        ++LGF
Sbjct: 158 VSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFP-----QPEAFWWRASRLYTLVLGF 212

Query: 277 VLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSF 335
            +P+  I + Y  LL R  A R  +  K            A  R   +VT  V  ++   
Sbjct: 213 AIPVSTICVLYTTLLCRLHAMRLDSHAK------------ALERAKKRVTFLVVAILAVC 260

Query: 336 FLCWLPNQALTTWSILIKFNAVP--FSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVR 393
            LCW P    T  ++       P   +  YF+           L+++NSCLNP LY  + 
Sbjct: 261 LLCWTPYHLSTVVALTTDLPQTPLVIAISYFI---------TSLSYANSCLNPFLYAFLD 311

Query: 394 REFRKALKSLL 404
             FR+ L+ L+
Sbjct: 312 ASFRRNLRQLI 322


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score =  143 bits (361), Expect = 3e-34
 Identities = 111/370 (30%), Positives = 178/370 (48%), Gaps = 47/370 (12%)

Query: 38  SGNASLQLPDLWWELGLELPDGAPPGHPPGSG--GAESADTEARVRILISVVYWVVCALG 95
           S  A LQ P L+       P   P      SG  GA SA + A + I I+ +Y  VCA+G
Sbjct: 6   SAGAELQ-PPLFANASDAYPSACPSAGANASGPPGARSASSLA-LAIAITALYSAVCAVG 63

Query: 96  LAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMC 155
           L GN+LV++ +       K++ N+++ NLAL D     TLPF + +  ++  WPFG+ +C
Sbjct: 64  LLGNVLVMFGIVRYTKM-KTATNIYIFNLALADALATSTLPFQSAKYLME-TWPFGELLC 121

Query: 156 KIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAK 215
           K V  +   NM+ S+F LT MSV RY +V   +K+   R   +               AK
Sbjct: 122 KAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAK---------------AK 166

Query: 216 ALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLG 275
            + + IW LA+   +P  + + T    G  +C+++FP         +W  +      L  
Sbjct: 167 LINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPS-----PSWYWDTVTKICVFLFA 221

Query: 276 FVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLS 334
           FV+P+ II +CY L+L+R  + R  +G+K               R L ++T+ V +VV +
Sbjct: 222 FVVPILIITVCYGLMLLRLRSVRLLSGSK------------EKDRSLRRITRMVLVVVGA 269

Query: 335 FFLCWLP-NQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVR 393
           F +CW P +  +  W+++      P         V A  + + L ++NS LNPVLY  + 
Sbjct: 270 FVVCWAPIHIFVIVWTLVDIDRRDPL-------VVAALHLCIALGYANSSLNPVLYAFLD 322

Query: 394 REFRKALKSL 403
             F++  + L
Sbjct: 323 ENFKRCFRQL 332


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score =  142 bits (359), Expect = 5e-34
 Identities = 115/392 (29%), Positives = 171/392 (43%), Gaps = 52/392 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALKSLL----WRIASPSITSMR------PFTATTKPEHEDQG 430
           NSCLNPVLY  +   F++  +         I   + T +R      P TA T      Q 
Sbjct: 330 NSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQC 389

Query: 431 LQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDL 462
           L  P+    A E   L   PG +     RYDL
Sbjct: 390 LPIPSLSCWALEQGCLVVYPGPLQGPLVRYDL 421


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  141 bits (356), Expect = 1e-33
 Identities = 106/358 (29%), Positives = 166/358 (46%), Gaps = 51/358 (14%)

Query: 52  LGLELPDGAPPGHPPGSGG---AESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKS 108
           LG   P  A     P       A   D  A   + I  +Y +VC +GL GN LV++++  
Sbjct: 15  LGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILR 74

Query: 109 MQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYA 168
                K++ N+++ NLA+ D  F+L++PF A   AL   WPFG  +C+ V  V  +NM+ 
Sbjct: 75  YAKM-KTATNIYLLNLAVADELFMLSVPFVASSAALRH-WPFGSVLCRAVLSVDGLNMFT 132

Query: 169 SVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALA 228
           SVF LT +SV RY +V   L++   R                   AK + + +W  + L 
Sbjct: 133 SVFCLTVLSVDRYVAVVHPLRAATYRRPS---------------VAKLINLGVWLASLLV 177

Query: 229 SLPSAIFSTTVKVMGEE--LCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILC 286
           +LP AIF+ T    G +   C +++P          W  ++     LLGF+LP+  I LC
Sbjct: 178 TLPIAIFADTRPARGGQAVACNLQWP-------HPAWSAVFVVYTFLLGFLLPVLAIGLC 230

Query: 287 YLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALT 346
           YLL+V      RA   + G             R   K+T+ V +VV+ F LCW+P   + 
Sbjct: 231 YLLIV---GKMRAVALRAG--------WQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQ 279

Query: 347 TWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLL 404
             ++ +       +            VS+ L+++NSC NP+LY  +   FR+  + +L
Sbjct: 280 LLNLFVTSLDATVNH-----------VSLILSYANSCANPILYGFLSDNFRRFFQRVL 326


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  141 bits (355), Expect = 1e-33
 Identities = 102/323 (31%), Positives = 159/323 (49%), Gaps = 42/323 (13%)

Query: 80  VRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWA 139
           +++ I  +Y  VC  GL GN LV+Y++       K++ N+++ NLAL D   +LTLPF  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKM-KTATNIYIFNLALADTLVLLTLPFQG 108

Query: 140 VENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRG 199
            +  L F WPFG A+CK V  +   NM+ S F LTAMSV RY ++   +++   R   + 
Sbjct: 109 TDILLGF-WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSK- 166

Query: 200 DCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEEL-CLVRFPDKLLGR 258
                         A+A+ V IWALA++  +P AI   + +V  EE+ CLV  P      
Sbjct: 167 --------------AQAVNVAIWALASVVGVPVAIMG-SAQVEDEEIECLVEIP-----T 206

Query: 259 DRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASA 318
            + +W  ++     L  F++P+ +I +CY L++R +        +G   ++G R      
Sbjct: 207 PQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRL--------RGVRLLSGSR---EKD 255

Query: 319 RRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLA 378
           R L ++T+ V +VV  F  CW P Q      +L +   V  S E     V        L 
Sbjct: 256 RNLRRITRLVLVVVAVFVGCWTPVQVF----VLAQGLGVQPSSE---TAVAILRFCTALG 308

Query: 379 HSNSCLNPVLYCLVRREFRKALK 401
           + NSCLNP+LY  +   F+   +
Sbjct: 309 YVNSCLNPILYAFLDENFKACFR 331


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  141 bits (355), Expect = 1e-33
 Identities = 102/323 (31%), Positives = 159/323 (49%), Gaps = 42/323 (13%)

Query: 80  VRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWA 139
           +++ I  +Y  VC  GL GN LV+Y++       K++ N+++ NLAL D   +LTLPF  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKM-KTATNIYIFNLALADTLVLLTLPFQG 108

Query: 140 VENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRG 199
            +  L F WPFG A+CK V  +   NM+ S F LTAMSV RY ++   +++   R   + 
Sbjct: 109 TDILLGF-WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSK- 166

Query: 200 DCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEEL-CLVRFPDKLLGR 258
                         A+A+ V IWALA++  +P AI   + +V  EE+ CLV  P      
Sbjct: 167 --------------AQAVNVAIWALASVVGVPVAIMG-SAQVEDEEIECLVEIP-----T 206

Query: 259 DRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASA 318
            + +W  ++     L  F++P+ +I +CY L++R +        +G   ++G R      
Sbjct: 207 PQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRL--------RGVRLLSGSR---EKD 255

Query: 319 RRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLA 378
           R L ++T+ V +VV  F  CW P Q      +L +   V  S E     V        L 
Sbjct: 256 RNLRRITRLVLVVVAVFVGCWTPVQVF----VLAQGLGVQPSSE---TAVAILRFCTALG 308

Query: 379 HSNSCLNPVLYCLVRREFRKALK 401
           + NSCLNP+LY  +   F+   +
Sbjct: 309 YVNSCLNPILYAFLDENFKACFR 331


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score =  139 bits (349), Expect = 7e-33
 Identities = 107/369 (28%), Positives = 165/369 (44%), Gaps = 54/369 (14%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 164 ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 221

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 222 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 269

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 270 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 321

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 322 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 369

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 370 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 422

Query: 381 NSCLNPVLYCLVRREFRKALKSLL----WRIASPSITSMR------PFTATT--KPEHED 428
           NSCLNPVLY  +   F++  +         I   + T +R      P TA T  +  H+ 
Sbjct: 423 NSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQL 482

Query: 429 QGLQAPAPP 437
           + L+A   P
Sbjct: 483 ENLEAETAP 491


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score =  139 bits (349), Expect = 7e-33
 Identities = 107/369 (28%), Positives = 165/369 (44%), Gaps = 54/369 (14%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALKSLL----WRIASPSITSMR------PFTATT--KPEHED 428
           NSCLNPVLY  +   F++  +         I   + T +R      P TA T  +  H+ 
Sbjct: 330 NSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQL 389

Query: 429 QGLQAPAPP 437
           + L+A   P
Sbjct: 390 ENLEAETAP 398


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
          Length = 389

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
          Length = 418

 Score =  137 bits (344), Expect = 3e-32
 Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 42/321 (13%)

Query: 82  ILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE 141
           I I  +Y +VC +GL GN LV+Y++       K++ N+++ NLAL D     TLPF +V 
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKM-KTATNIYIFNLALADALATSTLPFQSV- 128

Query: 142 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC 201
           N L   WPFG  +CKIV  +   NM+ S+F L  MSV RY +V   +K            
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK------------ 176

Query: 202 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ 261
              +L      +AK + V  W L++   LP    +TT    G   C + F          
Sbjct: 177 ---ALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-----SHPTW 228

Query: 262 FWLGLYHSQKVLLGFVLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARR 320
           +W  L      +  F++P+ II +CY L+++R  + R  +G+K               R 
Sbjct: 229 YWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSK------------EKDRN 276

Query: 321 LSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHS 380
           L ++T+ V +VV  F +CW P         L+      F       Q  ++   + L ++
Sbjct: 277 LRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTF-------QTVSWHFCIALGYT 329

Query: 381 NSCLNPVLYCLVRREFRKALK 401
           NSCLNPVLY  +   F++  +
Sbjct: 330 NSCLNPVLYAFLDENFKRCFR 350


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,599,501
Number of Sequences: 37866
Number of extensions: 850044
Number of successful extensions: 5523
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 284
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4219
Number of HSP's gapped (non-prelim): 543
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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