Search of human proteins with 7706083

Search of human proteins with 7706083

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706083 complement component 1, r subcomponent-like
precursor [Homo sapiens]
         (487 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706083 complement component 1, r subcomponent-like precursor...  1030   0.0  
gi|66347875 complement component 1, r subcomponent [Homo sapiens]     391   e-109
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...   181   2e-45
gi|4502495 complement component 1, s subcomponent precursor [Hom...   179   5e-45
gi|41393602 complement component 1, s subcomponent precursor [Ho...   179   5e-45
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...   170   2e-42
gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]       136   5e-32
gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]         136   5e-32
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...   130   2e-30
gi|45580723 haptoglobin-related protein [Homo sapiens]                129   5e-30
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           121   2e-27
gi|4503635 coagulation factor II preproprotein [Homo sapiens]         118   1e-26
gi|4503625 coagulation factor X preproprotein [Homo sapiens]          117   2e-26
gi|4506115 protein C [Homo sapiens]                                   110   3e-24
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]         110   4e-24
gi|148806900 epidermis-specific serine protease-like protein [Ho...   107   2e-23
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          107   2e-23
gi|13994276 marapsin [Homo sapiens]                                   106   4e-23
gi|33695155 hepsin [Homo sapiens]                                     106   5e-23
gi|4504481 hepsin [Homo sapiens]                                      106   5e-23
gi|4506143 neurotrypsin precursor [Homo sapiens]                      105   1e-22
gi|34098976 marapsin 2 [Homo sapiens]                                 104   2e-22
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            104   2e-22
gi|148231605 ovochymase 2 [Homo sapiens]                              104   2e-22
gi|4506153 prostasin preproprotein [Homo sapiens]                     103   4e-22
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   103   5e-22
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             102   6e-22
gi|4503627 coagulation factor XI precursor [Homo sapiens]             102   1e-21
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          102   1e-21
gi|110815798 ovochymase 1 [Homo sapiens]                              102   1e-21

>gi|7706083 complement component 1, r subcomponent-like precursor
           [Homo sapiens]
          Length = 487

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 1   MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEP 60
           MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEP
Sbjct: 1   MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEP 60

Query: 61  YGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLG 120
           YGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLG
Sbjct: 61  YGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLG 120

Query: 121 RPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQPISEASRGSEA 180
           RPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQPISEASRGSEA
Sbjct: 121 RPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQPISEASRGSEA 180

Query: 181 INAPGDNPAKVQNHCQEPYYQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIA 240
           INAPGDNPAKVQNHCQEPYYQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIA
Sbjct: 181 INAPGDNPAKVQNHCQEPYYQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIA 240

Query: 241 QNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVN 300
           QNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVN
Sbjct: 241 QNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVN 300

Query: 301 VFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCL 360
           VFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCL
Sbjct: 301 VFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCL 360

Query: 361 PDNETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMF 420
           PDNETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMF
Sbjct: 361 PDNETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMF 420

Query: 421 CVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGYDFYTKVLSYVDWIK 480
           CVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGYDFYTKVLSYVDWIK
Sbjct: 421 CVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGYDFYTKVLSYVDWIK 480

Query: 481 GVMNGKN 487
           GVMNGKN
Sbjct: 481 GVMNGKN 487


>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
          Length = 705

 Score =  391 bits (1004), Expect = e-109
 Identities = 176/303 (58%), Positives = 226/303 (74%), Gaps = 9/303 (2%)

Query: 189 AKVQNHCQEPYYQA--------AAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIA 240
           A++Q +C EPYY+         +  G  TC   G WK+ Q GE++ +C+PVCG+PV P+ 
Sbjct: 400 ARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVE 459

Query: 241 QNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVN 300
           Q Q  +G  +AK+GNFPWQ FT+IHGRGGGALLGDRWILTAAHT+YPK+  + + N S++
Sbjct: 460 QRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEA-QSNASLD 518

Query: 301 VFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCL 360
           VFLGHT ++E++KLGNHP+ RV VHPDYRQ+ES+NF GDIALLEL++S+ LGPN+LP+CL
Sbjct: 519 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 578

Query: 361 PDNETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMF 420
           PDN+T Y  GL+GYVSGFG+    +  +L++ RLPVA  +AC  WL+ + R +VFS NMF
Sbjct: 579 PDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 638

Query: 421 CVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGYDFYTKVLSYVDWIK 480
           C G  + +   CQGDSG V+ V D +   WVATGIVSWGIGC  GY FYTKVL+YVDWIK
Sbjct: 639 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIK 698

Query: 481 GVM 483
             M
Sbjct: 699 KEM 701



 Score =  127 bits (319), Expect = 2e-29
 Identities = 72/157 (45%), Positives = 94/157 (59%), Gaps = 3/157 (1%)

Query: 24  MWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF 83
           MW L L      C   GS+ + Q+L  ++TSP +P+PY    E++T I  P G+ V+LVF
Sbjct: 1   MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVF 60

Query: 84  QDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQP 143
           Q FDLEPS+ C  D V IS       +FCGQ GSPLG PPG++EF+S G  + LTF T  
Sbjct: 61  QQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDF 120

Query: 144 SS-ENKTAHLHKGFLALYQTVAVNYSQPISEASRGSE 179
           S+ EN T   +KGFLA YQ  AV+  +  S +  G E
Sbjct: 121 SNEENGTIMFYKGFLAYYQ--AVDLDECASRSKLGEE 155



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 17/139 (12%)

Query: 35  ACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF-QDFDLEPSQD 93
           +C    S  L  E    ++S  YP  Y      +  I+   G  + L F + FD++  Q 
Sbjct: 188 SCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQ 247

Query: 94  --CAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENKTAH 151
             C  D + I   G +  +FCG+Q     RPP   +  +S  ++ L F T  S ++    
Sbjct: 248 VHCPYDQLQIYANGKNIGEFCGKQ-----RPP---DLDTSSNAVDLLFFTDESGDS---- 295

Query: 152 LHKGFLALYQTVAVNYSQP 170
             +G+   Y T  +   QP
Sbjct: 296 --RGWKLRYTTEIIKCPQP 312


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score =  181 bits (458), Expect = 2e-45
 Identities = 110/324 (33%), Positives = 163/324 (50%), Gaps = 36/324 (11%)

Query: 189 AKVQNHCQEPYYQAAA--AGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQN-QTT 245
           ++++  CQEPYY+      G  TC+  G W ++  G  +  C+P CG+P   +    +  
Sbjct: 391 SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRI 450

Query: 246 LGSSRAKLGNFPWQAFTSIHGR---------GGGALLGDRWILTAAHTVYPK---DSVSL 293
           +G   A+ G FPWQA   +            G GALL   WILTAAH +  +    +V  
Sbjct: 451 IGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIP 510

Query: 294 RKNQSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGP 353
              + V V+LG   + +     N    RVV+HPD+      N++ DIAL++LQ  +PLGP
Sbjct: 511 VSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFN---IQNYNHDIALVQLQEPVPLGP 567

Query: 354 NVLPVCLPDNETLYRSG-LLGYVSGFGMEMGWLTTE-------------LKYSRLPVAPR 399
           +V+PVCLP  E    +  +LG V+G+G+    +T +             L+Y +LPV P 
Sbjct: 568 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 627

Query: 400 EACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWG 459
             C    + R      ++NMFC G        C GDSG  +V++D+ +  WV  G+VSWG
Sbjct: 628 AECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWG 687

Query: 460 ----IGCGEGYDFYTKVLSYVDWI 479
                G  + Y  YTKV +YVDW+
Sbjct: 688 GPEECGSKQVYGVYTKVSNYVDWV 711



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 47/145 (32%), Positives = 73/145 (50%), Gaps = 6/145 (4%)

Query: 24  MWWLLLWGVLQACPTRGSVLLAQ--ELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRL 81
           M WLLL+  L    ++ S    +   +  Q+ SPGYP+ Y    E + +I  P+GF ++L
Sbjct: 1   MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL 60

Query: 82  VFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRT 141
            F  F+LE S  C  D V +       + FCG++ +   + PGQ   +S G  + +TFR+
Sbjct: 61  YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS 120

Query: 142 QPSSENKTAHLHKGFLALYQTVAVN 166
             S+E +      GF A Y  V V+
Sbjct: 121 DFSNEER----FTGFDAHYMAVDVD 141



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 11/100 (11%)

Query: 52  LTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQD-FDLE--PSQDCAGDSVTISFVGSDP 108
           +TSP +P PY K  E    I+  EGF V L F+D FD+E  P   C  D + I       
Sbjct: 197 ITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVL 256

Query: 109 SQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENK 148
             FCG++              +   S+ + F +  S EN+
Sbjct: 257 GPFCGEK--------APEPISTQSHSVLILFHSDNSGENR 288


>gi|4502495 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  179 bits (454), Expect = 5e-45
 Identities = 115/307 (37%), Positives = 157/307 (51%), Gaps = 31/307 (10%)

Query: 195 CQEPYY--QAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAK 252
           C+EPYY  +    G   CA  G+W +   G E+ +C+PVCG P  P  + Q  +G S A 
Sbjct: 386 CEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDAD 445

Query: 253 LGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAI--DE 310
           + NFPWQ F   +   GGAL+ + W+LTAAH V          N+   +++G T++    
Sbjct: 446 IKNFPWQVFFD-NPWAGGALINEYWVLTAAHVV--------EGNREPTMYVGSTSVQTSR 496

Query: 311 MLKLGNHPVHRVVVHPDYRQNE----SHNFSGDIALLELQHSIPLGPNVLPVCLPDNETL 366
           + K        V +HP ++  E      NF  DIAL+ L+  + +GP V P+CLP   + 
Sbjct: 497 LAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSD 556

Query: 367 YR--SGLLGYVSGFG-MEMGWLTTELKYSRLPVAPREACNAWLQKRQRPE------VFSD 417
           Y    G LG +SG+G  E       LK +RLPVAP   C     K ++P       VF+ 
Sbjct: 557 YNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKE--VKVEKPTADAEAYVFTP 614

Query: 418 NMFCVGDETQRHSVCQGDSGSVYVVWD-NHAHHWVATGIVSWGIGCGEGYDFYTKVLSYV 476
           NM C G E    S C+GDSG  + V D N    + A G+VSWG  CG  Y  YT+V +YV
Sbjct: 615 NMICAGGEKGMDS-CKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYTRVKNYV 672

Query: 477 DWIKGVM 483
           DWI   M
Sbjct: 673 DWIMKTM 679



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 10/143 (6%)

Query: 24  MWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF 83
           MW ++L+ +L        V     +  ++ SP YP+ Y    E S DI+ PEG+ + L F
Sbjct: 1   MWCIVLFSLL------AWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYF 54

Query: 84  QDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQP 143
              D+E S++CA DSV I    ++  + CGQ+ S     P   EF      L++ F++  
Sbjct: 55  THLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDF 114

Query: 144 SSENKTAHLHKGFLALYQTVAVN 166
           S+E +      GF A Y    +N
Sbjct: 115 SNEER----FTGFAAYYVATDIN 133



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 10/102 (9%)

Query: 51  QLTSPGYPEPYGKGQESSTDIKAPEGF--AVRLVFQDFDLEPSQDCAGDSVTISFVGSDP 108
           ++ SP YP+PY +       I+  +GF   V L  +DFD+E +        ++ FV  D 
Sbjct: 186 EIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDR 245

Query: 109 --SQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENK 148
               +CG         PG     +   +L + F+T  + + K
Sbjct: 246 QFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQKK 281


>gi|41393602 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  179 bits (454), Expect = 5e-45
 Identities = 115/307 (37%), Positives = 157/307 (51%), Gaps = 31/307 (10%)

Query: 195 CQEPYY--QAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAK 252
           C+EPYY  +    G   CA  G+W +   G E+ +C+PVCG P  P  + Q  +G S A 
Sbjct: 386 CEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDAD 445

Query: 253 LGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAI--DE 310
           + NFPWQ F   +   GGAL+ + W+LTAAH V          N+   +++G T++    
Sbjct: 446 IKNFPWQVFFD-NPWAGGALINEYWVLTAAHVV--------EGNREPTMYVGSTSVQTSR 496

Query: 311 MLKLGNHPVHRVVVHPDYRQNE----SHNFSGDIALLELQHSIPLGPNVLPVCLPDNETL 366
           + K        V +HP ++  E      NF  DIAL+ L+  + +GP V P+CLP   + 
Sbjct: 497 LAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSD 556

Query: 367 YR--SGLLGYVSGFG-MEMGWLTTELKYSRLPVAPREACNAWLQKRQRPE------VFSD 417
           Y    G LG +SG+G  E       LK +RLPVAP   C     K ++P       VF+ 
Sbjct: 557 YNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKE--VKVEKPTADAEAYVFTP 614

Query: 418 NMFCVGDETQRHSVCQGDSGSVYVVWD-NHAHHWVATGIVSWGIGCGEGYDFYTKVLSYV 476
           NM C G E    S C+GDSG  + V D N    + A G+VSWG  CG  Y  YT+V +YV
Sbjct: 615 NMICAGGEKGMDS-CKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYTRVKNYV 672

Query: 477 DWIKGVM 483
           DWI   M
Sbjct: 673 DWIMKTM 679



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 10/143 (6%)

Query: 24  MWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF 83
           MW ++L+ +L        V     +  ++ SP YP+ Y    E S DI+ PEG+ + L F
Sbjct: 1   MWCIVLFSLL------AWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYF 54

Query: 84  QDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQP 143
              D+E S++CA DSV I    ++  + CGQ+ S     P   EF      L++ F++  
Sbjct: 55  THLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDF 114

Query: 144 SSENKTAHLHKGFLALYQTVAVN 166
           S+E +      GF A Y    +N
Sbjct: 115 SNEER----FTGFAAYYVATDIN 133



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 10/102 (9%)

Query: 51  QLTSPGYPEPYGKGQESSTDIKAPEGF--AVRLVFQDFDLEPSQDCAGDSVTISFVGSDP 108
           ++ SP YP+PY +       I+  +GF   V L  +DFD+E +        ++ FV  D 
Sbjct: 186 EIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDR 245

Query: 109 --SQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENK 148
               +CG         PG     +   +L + F+T  + + K
Sbjct: 246 QFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQKK 281


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score =  170 bits (431), Expect = 2e-42
 Identities = 143/503 (28%), Positives = 211/503 (41%), Gaps = 82/503 (16%)

Query: 51  QLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF-QDFDLE--PSQDCAGDSVTISFVGSD 107
           +L+SP YP PY K    +  I   EGF+V L F + FD+E  P   C  D + I     +
Sbjct: 195 ELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREE 254

Query: 108 PSQFCG---------------------QQGS-----------------PLGRPPGQREFV 129
              FCG                     + G                  P+  P G    V
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPV 314

Query: 130 SSGRSLRLTFRT--QPSSENKTAHLH-KGFLALYQTVA-----------VNYSQPISEAS 175
            +   L+ +F    +   E    HL  K F A+ Q              V+   P    S
Sbjct: 315 QAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPS 374

Query: 176 RGSEAINAPGDNPAK--VQNHCQEPYYQAAAA-GALTCATPGTWKDRQDGEEVLQCMPVC 232
              E I  PG    K  +Q  C+E +Y      G   C   G W   +  + +  C PVC
Sbjct: 375 GRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVC 434

Query: 233 GRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVS 292
           G  ++         G  +AK G+FPWQ          GALL D W+LTAAH VY +    
Sbjct: 435 G--LSARTTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQK--- 489

Query: 293 LRKNQSVNVFLGHTAIDEMLKLGNHPV----HRVVVHPDYRQNESHNFSGDIALLELQHS 348
                ++++ +G      + +L  H        V +H  Y  +    F  DIAL++L + 
Sbjct: 490 -HDASALDIRMG-----TLKRLSPHYTQAWSEAVFIHEGYTHDA--GFDNDIALIKLNNK 541

Query: 349 IPLGPNVLPVCLP--DNETLYRSGLLGYVSGFGM-EMGWLTTELKYSRLPVAPREACNAW 405
           + +  N+ P+CLP  + E+  R+  +G  SG+G+ + G+L   L Y  +P+   + C A 
Sbjct: 542 VVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAA 601

Query: 406 LQKRQRPE-VFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWG-IGCG 463
            +K   P    + NM C G E+     C+GDSG   V  D+    W   GIVSWG + CG
Sbjct: 602 YEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCG 661

Query: 464 EG--YDFYTKVLSYVDWIKGVMN 484
           E   Y  YTKV++Y+ WI+ +++
Sbjct: 662 EAGQYGVYTKVINYIPWIENIIS 684



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 53/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 51  QLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQ 110
           +L SPG+P  Y   QE    + AP G+ +RL F  FDLE S  C  D V +S      + 
Sbjct: 29  RLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLAT 88

Query: 111 FCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQP 170
            CGQ+ +   R PG+  F S G SL +TFR+  S+E        GF A Y    ++  Q 
Sbjct: 89  LCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP----FTGFEAFYAAEDIDECQV 144

Query: 171 ISEASRGSEAINAPGDNPAKVQNHCQE---PYYQAAAAG 206
                       APG+ P    +HC      +Y +  AG
Sbjct: 145 ------------APGEAPT-CDHHCHNHLGGFYCSCRAG 170


>gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]
          Length = 347

 Score =  136 bits (342), Expect = 5e-32
 Identities = 89/310 (28%), Positives = 142/310 (45%), Gaps = 36/310 (11%)

Query: 191 VQNHCQEPY-YQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSS 249
           V+  C+  Y  +    G  T      W ++  G+++ +C  VCG+P  P    Q  LG  
Sbjct: 48  VRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGH 107

Query: 250 RAKLGNFPWQAFTSIHGR--GGGALLGDRWILTAAHTVYPKDSVSLRKNQ---SVNVFLG 304
               G+FPWQA    H     G  L+ ++W+LT A  ++   S +        ++ +++G
Sbjct: 108 LDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVG 167

Query: 305 HTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNE 364
              + E        + +VV+HP+Y Q        DI L++L+  + +   V+P+CLP  +
Sbjct: 168 KKQLVE--------IEKVVLHPNYSQV-------DIGLIKLKQKVSVNERVMPICLPSKD 212

Query: 365 TLYRSGLLGYVSGFGMEMGW-LTTELKYSRLPVAPREACNAWLQKRQRPE---------- 413
                G +GYVSG+G    +  T  LKY  LPVA ++ C    +    PE          
Sbjct: 213 YA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGV 271

Query: 414 --VFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEG-YDFYT 470
             + +++ FC G    +   C GD+GS + V D     W ATGI+S+   C    Y  Y 
Sbjct: 272 QPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYV 331

Query: 471 KVLSYVDWIK 480
           KV S  DW++
Sbjct: 332 KVTSIQDWVQ 341


>gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]
          Length = 406

 Score =  136 bits (342), Expect = 5e-32
 Identities = 89/310 (28%), Positives = 142/310 (45%), Gaps = 36/310 (11%)

Query: 191 VQNHCQEPY-YQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSS 249
           V+  C+  Y  +    G  T      W ++  G+++ +C  VCG+P  P    Q  LG  
Sbjct: 107 VRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGH 166

Query: 250 RAKLGNFPWQAFTSIHGR--GGGALLGDRWILTAAHTVYPKDSVSLRKNQ---SVNVFLG 304
               G+FPWQA    H     G  L+ ++W+LT A  ++   S +        ++ +++G
Sbjct: 167 LDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVG 226

Query: 305 HTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNE 364
              + E        + +VV+HP+Y Q        DI L++L+  + +   V+P+CLP  +
Sbjct: 227 KKQLVE--------IEKVVLHPNYSQV-------DIGLIKLKQKVSVNERVMPICLPSKD 271

Query: 365 TLYRSGLLGYVSGFGMEMGW-LTTELKYSRLPVAPREACNAWLQKRQRPE---------- 413
                G +GYVSG+G    +  T  LKY  LPVA ++ C    +    PE          
Sbjct: 272 YA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGV 330

Query: 414 --VFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEG-YDFYT 470
             + +++ FC G    +   C GD+GS + V D     W ATGI+S+   C    Y  Y 
Sbjct: 331 QPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYV 390

Query: 471 KVLSYVDWIK 480
           KV S  DW++
Sbjct: 391 KVTSIQDWVQ 400


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score =  130 bits (328), Expect = 2e-30
 Identities = 97/319 (30%), Positives = 139/319 (43%), Gaps = 30/319 (9%)

Query: 189 AKVQNHCQEPYYQAAA--AGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTL 246
           ++++  CQEPYY+      G  TC+  G W ++  G  +  C+PVCG P           
Sbjct: 391 SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSRKLMARIF 450

Query: 247 GSSRAKLGNFPWQAFTSIHGRG----GGALLGDRWILTAAHTVY----PKDSV----SLR 294
               A+ G  PW A  S H  G    GG+LLG  WI+TAAH ++    P+D       L 
Sbjct: 451 NGRPAQKGTTPWIAMLS-HLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDSDLL 509

Query: 295 KNQSVNVFLG-HTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGP 353
                 + LG H  +       +  V    +HP Y  N    F  D+AL+EL  S  L  
Sbjct: 510 SPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPN---TFENDVALVELLESPVLNA 566

Query: 354 NVLPVCLPDNETLYRSGLLGYVSGFGMEMGWLTTE-LKYSRLPVAPREACNAWLQKRQRP 412
            V+P+CLP+     + G +  VSG+G +      E L    +P+     C    QK   P
Sbjct: 567 FVMPICLPEGPQ--QEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTC----QKAYAP 620

Query: 413 --EVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDF 468
             +  + +M C G++      C GDSG   V  +     W   G VSWG  CG  + Y  
Sbjct: 621 LKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGV 680

Query: 469 YTKVLSYVDWIKGVMNGKN 487
           Y+ +    DWI+ V   +N
Sbjct: 681 YSYIHHNKDWIQRVTGVRN 699



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 47/145 (32%), Positives = 73/145 (50%), Gaps = 6/145 (4%)

Query: 24  MWWLLLWGVLQACPTRGSVLLAQ--ELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRL 81
           M WLLL+  L    ++ S    +   +  Q+ SPGYP+ Y    E + +I  P+GF ++L
Sbjct: 1   MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL 60

Query: 82  VFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRT 141
            F  F+LE S  C  D V +       + FCG++ +   + PGQ   +S G  + +TFR+
Sbjct: 61  YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS 120

Query: 142 QPSSENKTAHLHKGFLALYQTVAVN 166
             S+E +      GF A Y  V V+
Sbjct: 121 DFSNEER----FTGFDAHYMAVDVD 141



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 11/100 (11%)

Query: 52  LTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQD-FDLE--PSQDCAGDSVTISFVGSDP 108
           +TSP +P PY K  E    I+  EGF V L F+D FD+E  P   C  D + I       
Sbjct: 197 ITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVL 256

Query: 109 SQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENK 148
             FCG++              +   S+ + F +  S EN+
Sbjct: 257 GPFCGEK--------APEPISTQSHSVLILFHSDNSGENR 288


>gi|45580723 haptoglobin-related protein [Homo sapiens]
          Length = 348

 Score =  129 bits (325), Expect = 5e-30
 Identities = 85/294 (28%), Positives = 136/294 (46%), Gaps = 35/294 (11%)

Query: 206 GALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIH 265
           G  T      W ++  G+++ +C  VCG+P  P    Q  LG      G+FPWQA    H
Sbjct: 65  GVYTLNDKKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSH 124

Query: 266 GR--GGGALLGDRWILTAAHTVYPKDSVSLRKNQ---SVNVFLGHTAIDEMLKLGNHPVH 320
                G  L+ ++W+LT A  ++   S +        ++ +++G   + E        + 
Sbjct: 125 HNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVE--------IE 176

Query: 321 RVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFGM 380
           +VV+HP+Y Q        DI L++L+  + +   V+P+CLP ++     G +GYVSG+G 
Sbjct: 177 KVVLHPNYHQV-------DIGLIKLKQKVLVNERVMPICLP-SKNYAEVGRVGYVSGWGQ 228

Query: 381 EMGW-LTTELKYSRLPVAPREACNAWLQKRQRPE------------VFSDNMFCVGDETQ 427
              + LT  LKY  LPVA +  C    +    P+            + +++ FCVG    
Sbjct: 229 SDNFKLTDHLKYVMLPVADQYDCITHYEGSTCPKWKAPKSPVGVQPILNEHTFCVGMSKY 288

Query: 428 RHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEG-YDFYTKVLSYVDWIK 480
           +   C GD+GS + V D     W A GI+S+   C    Y  Y KV S   W++
Sbjct: 289 QEDTCYGDAGSAFAVHDLEEDTWYAAGILSFDKSCAVAEYGVYVKVTSIQHWVQ 342


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  121 bits (303), Expect = 2e-27
 Identities = 84/273 (30%), Positives = 137/273 (50%), Gaps = 25/273 (9%)

Query: 218 DRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGD 275
           D +DG +   C   CG        +   +G + +  G +PWQA   + GR   GGAL+ D
Sbjct: 556 DCRDGSDEEHCD--CGLQ----GPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD 609

Query: 276 RWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAIDEMLKLG-NHPVHRVVVHPDYRQNESH 334
           RW++TAAH  + +DS++        VFLG    +       +  V R+++HP Y + +SH
Sbjct: 610 RWVITAAHC-FQEDSMA--STVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHP-YHEEDSH 665

Query: 335 NFSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG--MEMGWLTTELKYS 392
           ++  D+ALL+L H +     V PVCLP     +  GL  +++G+G   E G ++  L+  
Sbjct: 666 DY--DVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKV 723

Query: 393 RLPVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVA 452
            + + P++ C+   + +  P      M C G    +   CQGDSG   +V    +  W  
Sbjct: 724 DVQLIPQDLCSEVYRYQVTP-----RMLCAGYRKGKKDACQGDSGGP-LVCKALSGRWFL 777

Query: 453 TGIVSWGIGCGEG--YDFYTKVLSYVDWIKGVM 483
            G+VSWG+GCG    +  YT++   + WI+ V+
Sbjct: 778 AGLVSWGLGCGRPNYFGVYTRITGVISWIQQVV 810


>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score =  118 bits (296), Expect = 1e-26
 Identities = 85/270 (31%), Positives = 125/270 (46%), Gaps = 53/270 (19%)

Query: 249 SRAKLGNFPWQAFTSIHGRG----GGALLGDRWILTAAHTV-YPKDSVSLRKNQSVNVFL 303
           S A++G  PWQ             G +L+ DRW+LTAAH + YP    +  +N       
Sbjct: 368 SDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN------- 420

Query: 304 GHTAIDEMLKLGNHP-------------VHRVVVHPDYRQNESHNFSGDIALLELQHSIP 350
                D ++++G H              + ++ +HP Y   E  N   DIAL++L+  + 
Sbjct: 421 -----DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRE--NLDRDIALMKLKKPVA 473

Query: 351 LGPNVLPVCLPDNET---LYRSGLLGYVSGFG-MEMGWLT-------TELKYSRLPVAPR 399
               + PVCLPD ET   L ++G  G V+G+G ++  W         + L+   LP+  R
Sbjct: 474 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 533

Query: 400 EACNAWLQKRQRPEVFSDNMFCVG---DETQRHSVCQGDSGSVYVVWDNHAHHWVATGIV 456
             C    + R      +DNMFC G   DE +R   C+GDSG  +V+     + W   GIV
Sbjct: 534 PVCKDSTRIR-----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIV 588

Query: 457 SWGIGCGEG--YDFYTKVLSYVDWIKGVMN 484
           SWG GC     Y FYT V     WI+ V++
Sbjct: 589 SWGEGCDRDGKYGFYTHVFRLKKWIQKVID 618


>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
          Length = 488

 Score =  117 bits (294), Expect = 2e-26
 Identities = 85/244 (34%), Positives = 113/244 (46%), Gaps = 27/244 (11%)

Query: 246 LGSSRAKLGNFPWQAFT---SIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVF 302
           +G    K G  PWQA        G  GG +L + +ILTAAH +Y        K   V V 
Sbjct: 236 VGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQA------KRFKVRVG 289

Query: 303 LGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPD 362
             +T  +E    G   VH V V   + +     +  DIA+L L+  I    NV P CLP+
Sbjct: 290 DRNTEQEE----GGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPE 345

Query: 363 N---ETLYRSGLLGYVSGFGM--EMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSD 417
               E+   +   G VSGFG   E G  +T LK   +P   R +C     K     + + 
Sbjct: 346 RDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC-----KLSSSFIITQ 400

Query: 418 NMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGE--GYDFYTKVLSY 475
           NMFC G +T++   CQGDSG  +V        +  TGIVSWG GC     Y  YTKV ++
Sbjct: 401 NMFCAGYDTKQEDACQGDSGGPHVT--RFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAF 458

Query: 476 VDWI 479
           + WI
Sbjct: 459 LKWI 462


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score =  110 bits (275), Expect = 3e-24
 Identities = 87/302 (28%), Positives = 131/302 (43%), Gaps = 55/302 (18%)

Query: 222 GEEVLQCMPV----CGRPVTPIAQNQTTL----------------GSSRAKLGNFPWQAF 261
           G+++LQC P     CGRP   + + ++ L                     + G+ PWQ  
Sbjct: 169 GDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVV 228

Query: 262 TSIHGRG---GGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAIDEMLKLG-NH 317
                +    G  L+   W+LTAAH         + +++ + V LG   +    K   + 
Sbjct: 229 LLDSKKKLACGAVLIHPSWVLTAAHC--------MDESKKLLVRLGEYDLRRWEKWELDL 280

Query: 318 PVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDN----ETLYRSGLLG 373
            +  V VHP+Y ++ + N   DIALL L     L   ++P+CLPD+      L ++G   
Sbjct: 281 DIKEVFVHPNYSKSTTDN---DIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQET 337

Query: 374 YVSGFGMEMGW-------LTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFCVGDET 426
            V+G+G             T  L + ++PV P   C+  +       + S+NM C G   
Sbjct: 338 LVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMS-----NMVSENMLCAGILG 392

Query: 427 QRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDFYTKVLSYVDWIKGVMN 484
            R   C+GDSG   V   +    W   G+VSWG GCG    Y  YTKV  Y+DWI G + 
Sbjct: 393 DRQDACEGDSGGPMVA--SFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIR 450

Query: 485 GK 486
            K
Sbjct: 451 DK 452


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score =  110 bits (274), Expect = 4e-24
 Identities = 81/244 (33%), Positives = 111/244 (45%), Gaps = 25/244 (10%)

Query: 246 LGSSRAKLGNFPWQAFTS--IHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFL 303
           +G   AK G FPWQ   +  +    GG+++ ++WI+TAAH V             + V  
Sbjct: 228 VGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV--------ETGVKITVVA 279

Query: 304 GHTAIDEMLKLGN-HPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPD 362
           G   I+E         V R++ H +Y     + ++ DIALLEL   + L   V P+C+ D
Sbjct: 280 GEHNIEETEHTEQKRNVIRIIPHHNYNA-AINKYNHDIALLELDEPLVLNSYVTPICIAD 338

Query: 363 NE--TLYRSGLLGYVSGFG--MEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDN 418
            E   ++     GYVSG+G     G     L+Y R+P+  R  C      R       +N
Sbjct: 339 KEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATC-----LRSTKFTIYNN 393

Query: 419 MFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDFYTKVLSYV 476
           MFC G        CQGDSG  +V           TGI+SWG  C     Y  YTKV  YV
Sbjct: 394 MFCAGFHEGGRDSCQGDSGGPHVTEVEGTS--FLTGIISWGEECAMKGKYGIYTKVSRYV 451

Query: 477 DWIK 480
           +WIK
Sbjct: 452 NWIK 455


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  107 bits (267), Expect = 2e-23
 Identities = 77/271 (28%), Positives = 121/271 (44%), Gaps = 32/271 (11%)

Query: 231 VCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG----GGALLGDRWILTAAHTVY 286
           VCG+PV     +   +G   A  G +PWQ   S+H       GG+L+ +R ILTAAH + 
Sbjct: 18  VCGQPV----YSSRVVGGQDAAAGRWPWQV--SLHFDHNFICGGSLVSERLILTAAHCIQ 71

Query: 287 PKDSVSLRKNQSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQ 346
           P  +       S  V+LG   + +  K   + V ++V+HP Y+       + D+ALL+L 
Sbjct: 72  PTWTTF-----SYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQDT-----TADVALLKLS 121

Query: 347 HSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFGMEMGWLTTE----LKYSRLPVAPREAC 402
             +     +LP+CLP            +V+G+G        +    L+ + +P+  R+AC
Sbjct: 122 SQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQAC 181

Query: 403 NAWLQK-----RQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVS 457
                           V  ++  C GD       C+GDSG       +    W+ TG+VS
Sbjct: 182 EQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGV--WIQTGVVS 239

Query: 458 WGIGCGEGY-DFYTKVLSYVDWIKGVMNGKN 487
           WG+ CG+     YT V+ Y  WI   ++  N
Sbjct: 240 WGLECGKSLPGVYTNVIYYQKWINATISRAN 270


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  107 bits (267), Expect = 2e-23
 Identities = 73/244 (29%), Positives = 111/244 (45%), Gaps = 21/244 (8%)

Query: 243 QTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKDSVSLRKNQSVN 300
           Q  LG + A+ G++PWQ    ++     GG+L+ + WILTAAH          R N +  
Sbjct: 185 QRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHC--------FRSNSNPR 236

Query: 301 VFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCL 360
            ++  + I          V  +++H +Y+     N   DIAL+ L++S+    ++  VCL
Sbjct: 237 DWIATSGISTTFPKLRMRVRNILIHNNYKSATHEN---DIALVRLENSVTFTKDIHSVCL 293

Query: 361 PDNETLYRSGLLGYVSGFGME--MGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDN 418
           P        G   YV+G+G +   G    EL+  ++ +   + CNA              
Sbjct: 294 PAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNA---PHSYNGAILSG 350

Query: 419 MFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDFYTKVLSYV 476
           M C G        CQGDSG   V  D+    W   GIVSWG  CG  +    YT+V +Y+
Sbjct: 351 MLCAGVPQGGVDACQGDSGGPLVQEDSR-RLWFIVGIVSWGDQCGLPDKPGVYTRVTAYL 409

Query: 477 DWIK 480
           DWI+
Sbjct: 410 DWIR 413


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  106 bits (265), Expect = 4e-23
 Identities = 79/278 (28%), Positives = 129/278 (46%), Gaps = 33/278 (11%)

Query: 222 GEEVLQCMPVCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWIL 279
           G +  +    CGRP          +G    + G +PWQ     +G    GG+L+ ++W+L
Sbjct: 16  GSQRAKAATACGRP----RMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVL 71

Query: 280 TAAHTVYPKDSVSLRKNQSVNVFLGHTAIDEMLKLGNHP----VHRVVVHPDYRQNESHN 335
           TAAH        SL +     V LG     ++++ G H     V +V  +P Y+   S  
Sbjct: 72  TAAHCFRNTSETSLYQ-----VLLGAR---QLVQPGPHAMYARVRQVESNPLYQGTAS-- 121

Query: 336 FSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG--MEMGWLTTE--LKY 391
            S D+AL+EL+  +P    +LPVCLPD   ++ +G+  +V+G+G   E   L     L+ 
Sbjct: 122 -SADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQK 180

Query: 392 SRLPVAPREACNAWLQK----RQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHA 447
             +P+     CN    K      +P+   ++M C G E  +   C+GDSG   V     +
Sbjct: 181 LAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS 240

Query: 448 HHWVATGIVSWGIGCGEGY--DFYTKVLSYVDWIKGVM 483
             W+  G++SWG GC        Y +V ++ +WI  ++
Sbjct: 241 --WLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  106 bits (264), Expect = 5e-23
 Identities = 88/263 (33%), Positives = 117/263 (44%), Gaps = 30/263 (11%)

Query: 232 CGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKD 289
           CGR   P+ +    +G     LG +PWQ      G    GG+LL   W+LTAAH    ++
Sbjct: 153 CGRRKLPVDR---IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209

Query: 290 SVSLRKNQSVNVFLGHTA--IDEMLKLGNHPVHRVVVHPDY---RQNESHNFSGDIALLE 344
            V  R      VF G  A      L+LG   V  VV H  Y   R   S   S DIAL+ 
Sbjct: 210 RVLSRWR----VFAGAVAQASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVH 262

Query: 345 LQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG--MEMGWLTTELKYSRLPVAPREAC 402
           L   +PL   + PVCLP        G +  V+G+G     G     L+ +R+P+   + C
Sbjct: 263 LSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVC 322

Query: 403 NA--WLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWD--NHAHHWVATGIVSW 458
           N   +   + +P+     MFC G        CQGDSG  +V  D  +    W   GIVSW
Sbjct: 323 NGADFYGNQIKPK-----MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW 377

Query: 459 GIGC--GEGYDFYTKVLSYVDWI 479
           G GC   +    YTKV  + +WI
Sbjct: 378 GTGCALAQKPGVYTKVSDFREWI 400


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  106 bits (264), Expect = 5e-23
 Identities = 88/263 (33%), Positives = 117/263 (44%), Gaps = 30/263 (11%)

Query: 232 CGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKD 289
           CGR   P+ +    +G     LG +PWQ      G    GG+LL   W+LTAAH    ++
Sbjct: 153 CGRRKLPVDR---IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209

Query: 290 SVSLRKNQSVNVFLGHTA--IDEMLKLGNHPVHRVVVHPDY---RQNESHNFSGDIALLE 344
            V  R      VF G  A      L+LG   V  VV H  Y   R   S   S DIAL+ 
Sbjct: 210 RVLSRWR----VFAGAVAQASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVH 262

Query: 345 LQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG--MEMGWLTTELKYSRLPVAPREAC 402
           L   +PL   + PVCLP        G +  V+G+G     G     L+ +R+P+   + C
Sbjct: 263 LSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVC 322

Query: 403 NA--WLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWD--NHAHHWVATGIVSW 458
           N   +   + +P+     MFC G        CQGDSG  +V  D  +    W   GIVSW
Sbjct: 323 NGADFYGNQIKPK-----MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW 377

Query: 459 GIGC--GEGYDFYTKVLSYVDWI 479
           G GC   +    YTKV  + +WI
Sbjct: 378 GTGCALAQKPGVYTKVSDFREWI 400


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  105 bits (261), Expect = 1e-22
 Identities = 85/268 (31%), Positives = 126/268 (47%), Gaps = 29/268 (10%)

Query: 231 VCGRPVTPIAQNQTTLGSSRAKLGNFPWQA---FTSIHGRG----GGALLGDRWILTAAH 283
           VCG  +    Q +  +G   +  G +PWQ      S HG G    G  LL   W+LTAAH
Sbjct: 618 VCGLRLLHRRQKRI-IGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676

Query: 284 TVYPKDSVSLRKNQSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALL 343
               K   +  ++ +V V   HT + E  +     V ++V+H +YR + S     DIAL+
Sbjct: 677 CF--KRYGNSTRSYAVRVGDYHTLVPEEFE-EEIGVQQIVIHREYRPDRSDY---DIALV 730

Query: 344 ELQ----HSIPLGPNVLPVCLPD-NETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAP 398
            LQ           +VLP CLP   E   ++    Y++G+G      +  L+ + +P+ P
Sbjct: 731 RLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLP 790

Query: 399 REACNAWLQKRQRPEVFSDNMFCVGD--ETQRHSVCQGDSGSVYVVWDNHAHHWVATGIV 456
           +  C    + R     F+  M C G+  E +R   CQGDSG   ++ +     WV  G+ 
Sbjct: 791 KRFCEERYKGR-----FTGRMLCAGNLHEHKRVDSCQGDSGGP-LMCERPGESWVVYGVT 844

Query: 457 SWGIGCG--EGYDFYTKVLSYVDWIKGV 482
           SWG GCG  +    YTKV ++V WIK V
Sbjct: 845 SWGYGCGVKDSPGVYTKVSAFVPWIKSV 872


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  104 bits (260), Expect = 2e-22
 Identities = 80/260 (30%), Positives = 123/260 (47%), Gaps = 34/260 (13%)

Query: 232 CGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG----GGALLGDRWILTAAHTVYP 287
           CGRP    +     LG   A    +PWQ   S+H  G    GG++L + W+L+AAH  + 
Sbjct: 51  CGRP----SMEGKILGGVPAPERKWPWQV--SVHYAGLHVCGGSILNEYWVLSAAHCFH- 103

Query: 288 KDSVSLRKNQSVNVFLGHTAIDEMLKLGNHP----VHRVVVHPDYRQNESHNFSGDIALL 343
                  +++++ ++  +  +  +   GNH     V+RV++HP Y     H   GD+AL+
Sbjct: 104 -------RDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMY--HPIGGDVALV 154

Query: 344 ELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFGM--EMGWLTTELKYSRLPVAPREA 401
           +L+  I    +VLPVCL   E    S    + +G+G+  + G  + EL+  +LP+     
Sbjct: 155 QLKTRIVFSESVLPVCLATPEVNLTSANC-WATGWGLVSKQGETSDELQEMQLPLILEPW 213

Query: 402 CNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIG 461
           C+  L       +  D M C GD     +VC+GDSG   V   N +  W+  GIVSWG G
Sbjct: 214 CH--LLYGHMSYIMPD-MLCAGDILNAKTVCEGDSGGPLVCEFNRS--WLQIGIVSWGRG 268

Query: 462 CGEGY--DFYTKVLSYVDWI 479
           C        Y  V  +  WI
Sbjct: 269 CSNPLYPGVYASVSYFSKWI 288


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  104 bits (259), Expect = 2e-22
 Identities = 82/251 (32%), Positives = 118/251 (47%), Gaps = 32/251 (12%)

Query: 246 LGSSRAKLGNFPWQAFTSIHGRG-----GGALLGDRWILTAAHTVYP--KDSVSLRKNQS 298
           +G   A    +PWQ    +HG       GG+L+  +W+LTAAH V P  KD  +LR    
Sbjct: 32  VGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR---- 87

Query: 299 VNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPV 358
           V +   H    + L     PV R++VHP +   +      DIALLEL+  + +  +V  V
Sbjct: 88  VQLREQHLYYQDQLL----PVSRIIVHPQFYTAQ---IGADIALLELEEPVNVSSHVHTV 140

Query: 359 CLPDNETLYRSGLLGYVSGFG----MEMGWLTTELKYSRLPVAPREACNA----WLQKRQ 410
            LP     +  G+  +V+G+G     E       LK  ++P+     C+A          
Sbjct: 141 TLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGD 200

Query: 411 RPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGY--DF 468
              +  D+M C G+ T+R S CQGDSG   V   N    W+  G+VSWG GC +      
Sbjct: 201 DVRIVRDDMLCAGN-TRRDS-CQGDSGGPLVCKVNGT--WLQAGVVSWGEGCAQPNRPGI 256

Query: 469 YTKVLSYVDWI 479
           YT+V  Y+DWI
Sbjct: 257 YTRVTYYLDWI 267


>gi|148231605 ovochymase 2 [Homo sapiens]
          Length = 564

 Score =  104 bits (259), Expect = 2e-22
 Identities = 66/225 (29%), Positives = 108/225 (48%), Gaps = 12/225 (5%)

Query: 246 LGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFL 303
           LG S+ + G++PWQ       +   GG+++  +W++TAAH +  ++ VS     +    L
Sbjct: 53  LGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDL 112

Query: 304 GHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDN 363
             T   E        +  V++HP +   +  ++  DIALL++  +   G  V P+CLP+ 
Sbjct: 113 SQTDPGEQTLT----IETVIIHPHFSTKKPMDY--DIALLKMAGAFQFGHFVGPICLPEL 166

Query: 364 ETLYRSGLLGYVSGFGM--EMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFC 421
              + +G +   +G+G   E G L+  L+   LP+   E C A L   +RP +      C
Sbjct: 167 REQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRP-ISGKTFLC 225

Query: 422 VGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGY 466
            G        CQGDSG   ++  N    W   G+ SWG+GCG G+
Sbjct: 226 TGFPDGGRDACQGDSGGS-LMCRNKKGAWTLAGVTSWGLGCGRGW 269



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 41  SVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVT 100
           +VL  + L Q L    YPE Y          +A +   ++L FQ  ++E S DC  D VT
Sbjct: 435 TVLFEEGLIQSLN---YPENYSDKANCDWIFQASKHHLIKLSFQSLEIEESGDCTSDYVT 491

Query: 101 I 101
           +
Sbjct: 492 V 492


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  103 bits (257), Expect = 4e-22
 Identities = 79/254 (31%), Positives = 113/254 (44%), Gaps = 22/254 (8%)

Query: 239 IAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKDSVSLRKN 296
           +A      G S A  G +PWQ   +  G    GG+L+ ++W+L+AAH  +P +       
Sbjct: 39  VAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHC-FPSE----HHK 93

Query: 297 QSVNVFLGHTAIDEMLKLGN-HPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNV 355
           ++  V LG   +D   +      +  ++ HP Y Q  S    GDIALL+L   I     +
Sbjct: 94  EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ---GDIALLQLSRPITFSRYI 150

Query: 356 LPVCLPDNETLYRSGLLGYVSGFG---MEMGWLTTE-LKYSRLPVAPREACNAWLQ---K 408
            P+CLP     + +GL   V+G+G     +  LT + L+   +P+  RE CN       K
Sbjct: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210

Query: 409 RQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGY 466
            + P    ++M C G        CQGDSG            W  TGIVSWG  CG     
Sbjct: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGL--WYLTGIVSWGDACGARNRP 268

Query: 467 DFYTKVLSYVDWIK 480
             YT   SY  WI+
Sbjct: 269 GVYTLASSYASWIQ 282


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  103 bits (256), Expect = 5e-22
 Identities = 75/241 (31%), Positives = 117/241 (48%), Gaps = 21/241 (8%)

Query: 246 LGSSRAKLGNFPWQAFTSIHGRG--GGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFL 303
           +G + + L  +PWQA     G    GG+++   WI+TAAH VY    + L K+ ++ V L
Sbjct: 218 VGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVY---DLYLPKSWTIQVGL 274

Query: 304 GHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDN 363
             + +D      +H V ++V H  Y+     N   DIAL++L   +     + PVCLP++
Sbjct: 275 V-SLLDNPAP--SHLVEKIVYHSKYKPKRLGN---DIALMKLAGPLTFNEMIQPVCLPNS 328

Query: 364 ETLYRSGLLGYVSGFGME---MGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMF 420
           E  +  G + + SG+G      G  +  L ++ +P+   + CN    +     + S +M 
Sbjct: 329 EENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICN---HRDVYGGIISPSML 385

Query: 421 CVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGE--GYDFYTKVLSYVDW 478
           C G  T     CQGDSG   V  +     W   G  S+GIGC E      YT+V S++DW
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRL--WKLVGATSFGIGCAEVNKPGVYTRVTSFLDW 443

Query: 479 I 479
           I
Sbjct: 444 I 444


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  102 bits (255), Expect = 6e-22
 Identities = 75/246 (30%), Positives = 117/246 (47%), Gaps = 28/246 (11%)

Query: 246 LGSSRAKLGNFPWQA-----FTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVN 300
           +G + +  G +PWQ       T+     GG+L+G +W+LTAAH     D + L+      
Sbjct: 392 VGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF---DGLPLQ--DVWR 446

Query: 301 VFLGHTAIDEMLK-LGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVC 359
           ++ G   + ++ K      +  +++H +Y+ +E ++   DIAL++LQ  +       P+C
Sbjct: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH---DIALIKLQAPLNYTEFQKPIC 503

Query: 360 LP---DNETLYRS-GLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVF 415
           LP   D  T+Y +  + G+  GF  E G +   L+   +P+   E C    QKR +    
Sbjct: 504 LPSKGDTSTIYTNCWVTGW--GFSKEKGEIQNILQKVNIPLVTNEEC----QKRYQDYKI 557

Query: 416 SDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDFYTKVL 473
           +  M C G +      C+GDSG   V    H   W   GI SWG GC   E    YTKV 
Sbjct: 558 TQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPGVYTKVA 615

Query: 474 SYVDWI 479
            Y+DWI
Sbjct: 616 EYMDWI 621


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  102 bits (253), Expect = 1e-21
 Identities = 77/248 (31%), Positives = 115/248 (46%), Gaps = 32/248 (12%)

Query: 246 LGSSRAKLGNFPWQAFTSIHGRG-------GGALLGDRWILTAAHTVYPKDSVSLRKNQS 298
           +G + +  G +PWQ   ++H          GG+++G++WILTAAH  Y  +S  + +  S
Sbjct: 389 VGGTASVRGEWPWQV--TLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446

Query: 299 VNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPV 358
               L  + I E        V  +++H  Y+  ES     DIALL+L+ ++    +  P+
Sbjct: 447 G--ILNQSEIKEDTSFFG--VQEIIIHDQYKMAES---GYDIALLKLETTVNYTDSQRPI 499

Query: 359 CLP---DNETLYRSGLLGYVSGFGMEM--GWLTTELKYSRLPVAPREACNAWLQKRQRPE 413
           CLP   D   +Y      +V+G+G       +   L+ +++P+   E C    QKR R  
Sbjct: 500 CLPSKGDRNVIYTDC---WVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC----QKRYRGH 552

Query: 414 VFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCG--EGYDFYTK 471
             +  M C G        C+GDSG       N   H V  GI SWG GC   E    YT 
Sbjct: 553 KITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLV--GITSWGEGCAQRERPGVYTN 610

Query: 472 VLSYVDWI 479
           V+ YVDWI
Sbjct: 611 VVEYVDWI 618


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  102 bits (253), Expect = 1e-21
 Identities = 83/275 (30%), Positives = 122/275 (44%), Gaps = 27/275 (9%)

Query: 216 WKDRQD---GEEV-LQCMPVCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRG--G 269
           W+ R +   G+ V L+C     RP+         +G      G +PWQA  ++  R   G
Sbjct: 190 WQPRNNCTSGQVVSLRCSECGARPLA-----SRIVGGQSVAPGRWPWQASVALGFRHTCG 244

Query: 270 GALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYR 329
           G++L  RW++TAAH ++   S  L +  S  V  G  +   +       V R++ HP Y 
Sbjct: 245 GSVLAPRWVVTAAHCMH---SFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLY- 300

Query: 330 QNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG---MEMGWLT 386
              + N   D+ALL LQ ++     V  VCLP  E  +  G   +VSG+G       + +
Sbjct: 301 --SAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSS 358

Query: 387 TELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNH 446
             L+ + +P+   + CN+           +  M C G    R   CQGDSG   V  D  
Sbjct: 359 DMLQDTVVPLFSTQLCNS---SCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGD 415

Query: 447 AHHWVATGIVSWGIGCGEGY--DFYTKVLSYVDWI 479
              W   G+VSWG GC E      Y KV  ++DWI
Sbjct: 416 T--WRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWI 448


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  102 bits (253), Expect = 1e-21
 Identities = 70/214 (32%), Positives = 105/214 (49%), Gaps = 12/214 (5%)

Query: 257 PWQAF--TSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAIDEMLKL 314
           PWQ    +  H   GG+L+ +  ++TAAH +   DS+S ++ +++ V  G  ++ +  K 
Sbjct: 59  PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCL---DSLSEKQLKNITVTSGEYSLFQKDKQ 115

Query: 315 G-NHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLG 373
             N PV +++ HP+Y   E    S DIALL L+H +  G  V P+CLPD++     G+L 
Sbjct: 116 EQNIPVSKIITHPEYNSREY--MSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILC 173

Query: 374 YVSGFG--MEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSV 431
             SG+G   +    +  L+   LP+    ACN  L+    P +    M C G        
Sbjct: 174 LSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPL-GRTMLCAGFPDWGMDA 232

Query: 432 CQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEG 465
           CQGDSG   +V       W+  GI SW  GC  G
Sbjct: 233 CQGDSGGP-LVCRRGGGIWILAGITSWVAGCAGG 265



 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 81/266 (30%), Positives = 122/266 (45%), Gaps = 23/266 (8%)

Query: 231 VCG-RPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHG--RGGGALLGDRWILTAAHTVYP 287
           VCG  P +P   ++   G   A    +PWQ      G  + GGA++   WILTAAH V  
Sbjct: 560 VCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQL 619

Query: 288 KDSVSLRKNQSVNVFLGHTAIDEMLKLGNHPVHR---VVVHPDYRQNESHNFSGDIALLE 344
           K++       S  +  G    D  LK     V R   ++VH D+    + ++  DIAL++
Sbjct: 620 KNNPL-----SWTIIAGDH--DRNLKESTEQVRRAKHIIVHEDFN---TLSYDSDIALIQ 669

Query: 345 LQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFG--MEMGWLTTELKYSRLPVAPREAC 402
           L   +     V PVCLP +     S  +  V+G+G     G L + L+  ++ V  RE C
Sbjct: 670 LSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVC 729

Query: 403 NAWLQKRQRPEVFSDNMFCVG-DETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIG 461
                    P   ++ M C G   +     CQGDSG   V    +   +V  GIVSWG G
Sbjct: 730 EHTYYS-AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENG-PFVLYGIVSWGAG 787

Query: 462 CGEGY--DFYTKVLSYVDWIKGVMNG 485
           C + +    + +V+ ++DWI+  +NG
Sbjct: 788 CVQPWKPGVFARVMIFLDWIQSKING 813



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 17/48 (35%), Positives = 25/48 (52%)

Query: 54  SPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTI 101
           S  YP+ Y         I APE   ++L F+DF ++ S +C  D+V I
Sbjct: 433 SAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVI 480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,484,800
Number of Sequences: 37866
Number of extensions: 1125862
Number of successful extensions: 3101
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 2387
Number of HSP's gapped (non-prelim): 404
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.