Search of human proteins with 139394604

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|139394604 bromo adjacent homology domain containing 1 [Homo
sapiens]
         (780 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|139394604 bromo adjacent homology domain containing 1 [Homo s...  1636   0.0  
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]    69   2e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    68   3e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    67   6e-11
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         67   8e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          62   2e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          62   2e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          62   2e-09
gi|153792074 proline rich 12 [Homo sapiens]                            57   9e-08
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    55   2e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     55   2e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   2e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    55   3e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    54   4e-07
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    54   7e-07
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    54   7e-07
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    54   7e-07
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...    53   1e-06
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...    53   1e-06
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...    53   1e-06
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...    53   1e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    53   1e-06
gi|117938768 GNAS complex locus alex [Homo sapiens]                    51   4e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    51   4e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   6e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              50   1e-05
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    50   1e-05
gi|18959210 WIRE protein [Homo sapiens]                                49   2e-05
gi|188536004 zinc finger protein 469 [Homo sapiens]                    48   3e-05
gi|208022661 hypothetical protein LOC57701 [Homo sapiens]              48   3e-05

>gi|139394604 bromo adjacent homology domain containing 1 [Homo
           sapiens]
          Length = 780

 Score = 1636 bits (4236), Expect = 0.0
 Identities = 780/780 (100%), Positives = 780/780 (100%)

Query: 1   MTHTRRKSLPMLSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKNYPLRKR 60
           MTHTRRKSLPMLSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKNYPLRKR
Sbjct: 1   MTHTRRKSLPMLSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKNYPLRKR 60

Query: 61  PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLA 120
           PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLA
Sbjct: 61  PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLA 120

Query: 121 SLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGS 180
           SLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGS
Sbjct: 121 SLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGS 180

Query: 181 RDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPP 240
           RDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPP
Sbjct: 181 RDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPP 240

Query: 241 APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPL 300
           APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPL
Sbjct: 241 APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPL 300

Query: 301 SKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGN 360
           SKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGN
Sbjct: 301 SKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGN 360

Query: 361 PADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPS 420
           PADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPS
Sbjct: 361 PADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPS 420

Query: 421 SVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGC 480
           SVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGC
Sbjct: 421 SVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGC 480

Query: 481 RSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAK 540
           RSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAK
Sbjct: 481 RSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAK 540

Query: 541 PPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRRRRRTNGWVPVGAACEK 600
           PPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRRRRRTNGWVPVGAACEK
Sbjct: 541 PPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRRRRRTNGWVPVGAACEK 600

Query: 601 AVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGE 660
           AVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGE
Sbjct: 601 AVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGE 660

Query: 661 LMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFC 720
           LMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFC
Sbjct: 661 LMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFC 720

Query: 721 AMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ 780
           AMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ
Sbjct: 721 AMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ 780


>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
          Length = 2608

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 10/222 (4%)

Query: 499  PAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHT 558
            PA  L  C    VP        L++  S P   A+ C  S    +G+ +G    SS +  
Sbjct: 2354 PALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATVAGTGAGSGPSSSSKSK 2413

Query: 559  ARSKAARRPSHPKQ-PRVQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDE---PEPAIRK 614
             + K A   S  K+  R QRP P    R + + ++P     + +            A + 
Sbjct: 2414 LKRKEALSFSKAKELSRRQRP-PSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKL 2472

Query: 615  SYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHL 674
             Y+A+ R  ET+RV D  +  S  R  + PY+ +I ++WE+  S  +++ + W+Y PE  
Sbjct: 2473 FYKAIVRGEETLRVGDCAVFLSAGRP-NLPYIGRIESMWESWGSN-MVVKVKWFYHPEET 2530

Query: 675  QGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEY 716
            + G+     +   N ++ S H+D+N V  I  KC V+   +Y
Sbjct: 2531 KLGKRQCDGK---NALYQSCHEDENDVQTISHKCQVVAREQY 2569



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 157 RDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPK 202
           R++A G  +  K+RP   + GG  R     P P +G  R+G PAP+
Sbjct: 226 REKA-GKAAEGKERPAAEEDGGKERHKLVLPVPADGHCREGGPAPR 270


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 113/410 (27%), Positives = 145/410 (35%), Gaps = 68/410 (16%)

Query: 187  PAPDEGPRRDGDPAPKRLASLN-AAAFLKLSQERELPLRLPRAHAEVDGRSTEPPA---- 241
            P P EGP     PAPK+  +L+  ++  K ++    P  +P A     G  T P A    
Sbjct: 894  PFPKEGP---ATPAPKQAPALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPPS 949

Query: 242  ----PKAPRPKW---------PKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATP 288
                P  P PKW         P   G     + +GA +  AA PP  +G P  P P   P
Sbjct: 950  PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009

Query: 289  CGPSV-------QPSHQPLSKALESPLGLRPHLPLLMGGQAAL---KPEPGRPGEESPAP 338
              P+V        P+  P  K   +P    P  P   G  AA    K  P  P    P+P
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP--KGSPAATPLPKGAPTTPAATLPSP 1067

Query: 339  KQELHQPSF---PTPQLSPLPMP-GNPA--DYNGLCVGPELTALGSFYLYCGQEGLQCGG 392
            K     PS    PTP  +  P P G PA     G  + P  T          + GL    
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP------KGGLATPP 1121

Query: 393  YSPCPMLPEG-KLSP---VAAPHEEGLLLAPSSV---PSGTPFQHPPWGSSRYCSSEDTG 445
            +   P  P     SP   +A P  +G    P++    P G     PP G+    ++    
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 446  VNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLG 505
              G    G+   S   A TT    P   P    G  +      P   A  P SP    L 
Sbjct: 1182 PKG----GLATPSPKGAPTTPAATP---PSPKGGLATPSPKGAPTTPAATPPSPKGG-LA 1233

Query: 506  CP----VPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRT 551
             P     P+ P A  P P     T  P+      P +A PPS  K GL T
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPK--GAPTPPAATPPS-LKGGLAT 1280



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 93/383 (24%), Positives = 121/383 (31%), Gaps = 64/383 (16%)

Query: 234  GRSTEPP--APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
            G +T  P  AP  P    P   G     + +GA +  AA PP  +G P  P P   P  P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267

Query: 292  SVQPSH------QPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQP 345
            +  P         P  K   +P  + P  P    G  A  P  G P   +  P      P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPK---GGPATSPPKGAPTPPAATPPSPKGSP 1324

Query: 346  SFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLS 405
              P P+ +P P    P    G    P  T                 G    P   EG   
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK-------------GGPTTPSSKEGPTP 1371

Query: 406  PVAAP-HEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGT 464
            P A P H+ G  + P S   G     P          + T         V+PLS   A  
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSP--------KGDPTSP------AVIPLSPKKAPA 1417

Query: 465  T-----CGGCPYKMPFAAEGCRSLGQLEFPLPEA--GHPASPAH------PLLGCPVPSV 511
            T         P K          +   + P   A  G PA+P+       P +  P P  
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477

Query: 512  PPAAEPVPHLQTPTSEPQTVA--------RACPQSAKPPSGSKSGLRTGSSCRHTARSKA 563
            PPA + V    +P   P T A           P S K    + S  R   +   T  SK 
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537

Query: 564  ARRPSHPKQ----PRVQRPRPRR 582
                  PK+    P +  P P++
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKK 1560



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 133/555 (23%), Positives = 183/555 (32%), Gaps = 81/555 (14%)

Query: 54   NYPLRKR-PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLA 112
            N P  K  P  P   +A  + +T     + P+ A  A   P  +P  PSP  +   P   
Sbjct: 892  NLPFPKEGPATPAPKQAPALSMTS----SSPKKA-RATPAPKGIPASPSPKGAPTPPAAT 946

Query: 113  QPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPR 172
             P  +   +  +         +   +  A T  S  G P     +   T   +++   P+
Sbjct: 947  PPSPKGGPATPSP--------KWAPTPPAATPPSPKGGPATPSPKGAPTPP-AATPPSPK 997

Query: 173  LGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEV 232
                 GG    SP+ AP   P     P+PK   S  A  F K +     P   P +    
Sbjct: 998  -----GGPATPSPKGAPT--PPAVTPPSPK--GSPAATPFPKGASTP--PAATPPSPKGS 1046

Query: 233  DGRSTEPP-APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
               +  P  AP  P    P   G     + +GA +  AA PP  +G P  P P   P  P
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106

Query: 292  SVQPSH------QPLSKALESPLGLRPHLPLLMGGQAALKPE--PGRPGEESPAPKQELH 343
            +  P         P  K   +     P  P   GG A   P+  P  P    P+PK  L 
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSP--KGGLATPPPKGAPTTPAATPPSPKGGL- 1163

Query: 344  QPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGY-SPCP----- 397
              + P P+ +P      P    G    P  +  G+            GG  +P P     
Sbjct: 1164 --ATPPPKGAPTTPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 398  ---MLPEGKLSPVAAPHEEGLLLAPSSV---PSGTPFQHPPWGSSRYCSSEDTGVNGYSI 451
                 P      +A P  +G    P++    P G P   PP G+    ++    + G   
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 452  C----GVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCP 507
                 G    +V    +  GG     P  A           P P A  P SP     G P
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGA-----------PTPPAATPPSPK----GSP 1324

Query: 508  VPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRP 567
              + PP   P P   TP S   T     P        SK G  T SS      +  A  P
Sbjct: 1325 -GTPPPKGAPTPPAVTPPSPKGT-----PTLPATTPSSKGGPTTPSS--KEGPTPPAATP 1376

Query: 568  SHPKQPRVQRPRPRR 582
            SH   P +  P P+R
Sbjct: 1377 SHKGGPAMTPPSPKR 1391



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 92/377 (24%), Positives = 128/377 (33%), Gaps = 36/377 (9%)

Query: 222  PLRLPRAHAEVDGRS-TEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPD 280
            P   P    +VDG S T   AP A  PK         P    GAS+  A+         D
Sbjct: 741  PAGTPPGTKKVDGISHTSALAPVASSPK-------ECPTEDSGASA-TASSKGTLTYLAD 792

Query: 281  EPWPSATPCGPSVQ-PSHQPLSKALESPLG--LRPHLPLLMGGQAALKPEPGRPGEESPA 337
             P P      P  + P  +  S   ++P+G    P  P+    +A+  PE     + S  
Sbjct: 793  SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV----EASFLPENSLSFQGSKD 848

Query: 338  PKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFY-LYCGQEGLQCGGYSPC 396
                 H P+ P+P+ +P P    P    G+ + P+ T   S   L   +EG         
Sbjct: 849  SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908

Query: 397  PMLPEGKLSPV---AAPHEEGLLLAPS-----SVPSGTPFQ---HPPWGSSRYCSSEDTG 445
            P L     SP    A P  +G+  +PS     + P+ TP      P   S ++  +    
Sbjct: 909  PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968

Query: 446  VNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLG 505
                   G    S   A T     P   P    G  +      P P A  P SP      
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAATP---PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025

Query: 506  CPVP---SVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSK 562
             P P   S PPAA P     +P + P  + +  P +      S  G     S +      
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATP--LPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 563  AARRPSHPKQPRVQRPR 579
            AA  PS    P    P+
Sbjct: 1084 AATPPSPKGGPATPSPK 1100



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 112/510 (21%), Positives = 172/510 (33%), Gaps = 106/510 (20%)

Query: 61   PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLA 120
            P  P++P A K + T     + P+ A  A   P   P  P+  PSS     A P  RR  
Sbjct: 1472 PPSPKEPPAPKQVATS----SSPKKAP-ATPAPMGAPTLPAVIPSSPKEVPATPSSRR-- 1524

Query: 121  SLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGS 180
              +  A    LL ++  ++LA   +     P  +    + T    + K+ P        S
Sbjct: 1525 --DPIAPTATLLSKKTPATLAP--KEALIPPAMTVPSPKKTPAIPTPKEAPATPS----S 1576

Query: 181  RDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPP 240
            ++ S  PA      + G P+PK L                                  PP
Sbjct: 1577 KEASSPPAVTPSTYK-GAPSPKELLI--------------------------------PP 1603

Query: 241  APKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPL 300
            A  +P PK               A +  A  PP  +  P  P P  TP  P V PS   L
Sbjct: 1604 AVTSPSPK--------------EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS--SL 1647

Query: 301  SKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPL---PM 357
              +  SP  +   +     G    +   G P ++ P   +E+     P P+ +P+   P 
Sbjct: 1648 KDSPTSPASVTCKM-----GATVPQASKGLPAKKGPTALKEVLVA--PAPESTPIITAPT 1700

Query: 358  PGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLL 417
               P         P +    S     G +G      +P P+LP  K S   A  ++    
Sbjct: 1701 RKGPQTKKSSATSPPICPDPS--AKNGSKG-PLSTVAPAPLLPVQKDSSKTAKGKDA--- 1754

Query: 418  APSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAA 477
              S  P G P   P        S   T +   +   VLP   + + +     P  +P A 
Sbjct: 1755 --SHSPKG-PLAPPE-------SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804

Query: 478  EGCRSLGQLEFPLPEAGHPA--SPAHPLLGCP----VPSVPPAAEPVPH--------LQT 523
                +L   +  LP +      SP+ PL        +P +PP  EP+          +  
Sbjct: 1805 SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP--EPISGGVPFQSVLVNM 1862

Query: 524  PTSEPQTVARACPQSAKPPSGSKSGLRTGS 553
            PT +   +    P + +P + +  G  T S
Sbjct: 1863 PTPKSAGIPVPTPSAKQPVTKNNKGSGTES 1892



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 3/95 (3%)

Query: 478 EGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQ 537
           EG  SL     P+ E      P  P      P  P        L T    P+ + ++ P 
Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-IPKSVPS 736

Query: 538 SAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQ 572
            + PP+G+  G +      HT  S  A   S PK+
Sbjct: 737 PSLPPAGTPPGTKKVDGISHT--SALAPVASSPKE 769


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 125/472 (26%), Positives = 163/472 (34%), Gaps = 92/472 (19%)

Query: 88   EADELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSR 147
            EA  L P     P   P  E P    P   RL+ L    ++ L    E++        S 
Sbjct: 622  EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL--PVVSRLSPPPEESPLSPPPEESP 679

Query: 148  AGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASL 207
               P                   P    L     D    P P++ P             L
Sbjct: 680  TSPP-------------------PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720

Query: 208  NAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPK-APRPKWPKVNGKNYPKAWQGASS 266
              +  L L +E +L  R    H      S  P  P  +PRP+ P ++    P+A +   S
Sbjct: 721  EESPLLPLPEEPQLCPRSEGPHL-----SPRPEEPHLSPRPEEPHLS----PQAEEPHLS 771

Query: 267  GEAAGPPGWQGCPDEPWPSATPCGP--SVQPSHQPLSKALESP-LGLRPHLPLL--MGGQ 321
             +    P     P+EP  S    GP  S QP    LS   E P L   P  P L     +
Sbjct: 772  PQPE-EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830

Query: 322  AALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYL 381
            + L P+   P   SP P++    P    P LSP   P  P +  G C  PE   L   + 
Sbjct: 831  SHLSPQSEEPCL-SPRPEESHLSPELEKPPLSP--RPEKPPEEPGQCPAPEELPL---FP 884

Query: 382  YCGQEGLQCGGYSPCPMLPEGKLS----PVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSR 437
              G+  L        P+L E  LS    P  +P  E L L+PS  PS +P   PP     
Sbjct: 885  PPGEPSLS-------PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP----- 932

Query: 438  YCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAG--H 495
                             LP  ++         P     A      LG+LE+P    G   
Sbjct: 933  ---------------DPLPPPLS---------PIITAAAPPALSPLGELEYPFGAKGDSD 968

Query: 496  PASP-AHPLLGCPVPSVPPAA-----EPVPHLQTPTSEPQTVARACPQSAKP 541
            P SP A P+L  P+ S PP A     EPVP +  P S    V  A P   +P
Sbjct: 969  PESPLAAPILETPI-SPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEP 1019



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 135/530 (25%), Positives = 184/530 (34%), Gaps = 116/530 (21%)

Query: 56   PLRKRPLVP--EKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSP--APSSEDPGL 111
            PL + PL+P  E+P+ C           GP  +   +E P   P+P  P  +P +E+P L
Sbjct: 719  PLEESPLLPLPEEPQLCP-------RSEGPHLSPRPEE-PHLSPRPEEPHLSPQAEEPHL 770

Query: 112  A-QPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKR 170
            + QP +  L ++  E   +                 +A  PH S   +      S   + 
Sbjct: 771  SPQPEEPCLCAVPEEPHLS----------------PQAEGPHLSPQPEELH--LSPQTEE 812

Query: 171  PRLGDLGGGSRDLSPEPAPDEGPRRDGDP--APKRLASLNAAAFLKLSQERELPLRLPRA 228
            P L  +      LSP+P       +  +P  +P+   S        LS E E P   PR 
Sbjct: 813  PHLSPVPE-EPCLSPQPEESHLSPQSEEPCLSPRPEES-------HLSPELEKPPLSPRP 864

Query: 229  HA--EVDGRSTEPPA-PKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPS 285
                E  G+   P   P  P P  P ++    P   + A S    G P     P  P P 
Sbjct: 865  EKPPEEPGQCPAPEELPLFPPPGEPSLS----PLLGEPALS--EPGEP-----PLSPLPE 913

Query: 286  ATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQA--ALKP---------EPGRPGEE 334
              P  PS +PS   LS  L  P  L P L  ++   A  AL P           G    E
Sbjct: 914  ELPLSPSGEPS---LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE 970

Query: 335  SPAPKQELHQPSFPTPQLS--------PLPMPGNPADYNGLCVGPELTALGSFYLYCGQE 386
            SP     L  P  P P+ +        P+ +P +P    G  VGP    L         E
Sbjct: 971  SPLAAPILETPISPPPEANCTDPEPVPPMILPPSP----GSPVGPASPIL--------ME 1018

Query: 387  GLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSE---- 442
             L       C  L +  L P  +P  +    +P ++P   P    P G     S E    
Sbjct: 1019 PLP----PQCSPLLQHSLVPQNSPPSQ---CSPPALPLSVPSPLSPIGKVVGVSDEAELH 1071

Query: 443  --DTGVNGYSICGVLPLSVTHAGTTCGG---CPYKMPFAA-EGCRSLGQLEFPL------ 490
              +T       C  L  S T    +  G   CP   P  A +    LG+   PL      
Sbjct: 1072 EMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAP 1131

Query: 491  ---PEAGH-PASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACP 536
               PE G  P S A  L G PV   P    PV  ++      QT  +  P
Sbjct: 1132 GSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 87/385 (22%), Positives = 135/385 (35%), Gaps = 61/385 (15%)

Query: 177 GGGSRDLSPEPAPDEGPRR-DGDPAPKRLASLNAAAFLKLSQEREL---PLRLPRAHAEV 232
           GG    + P+   + GP + +  P  K    L       L++E  L   P   P +    
Sbjct: 398 GGHVTSMQPK---EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPE 454

Query: 233 DGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAA--GPPGWQGCPDEPWPSATPCG 290
           +  ++ PP      P   ++     P+A   +   E +   PP  +  P  P P ++P  
Sbjct: 455 ESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES-PLSPPPESSPFS 513

Query: 291 PSVQPSHQPLSKALESPLGLRPHLPLLMGGQAA-LKPEPGRPGEESPAPKQELHQPSFPT 349
           P  +    PLS   ESP       PL    +A+ L P    P EESP        P+ P 
Sbjct: 514 PLEE---SPLSPPEESPPSPALETPLSPPPEASPLSP----PFEESPLSPPPEELPTSPP 566

Query: 350 PQLSPLPMP------GNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGK 403
           P+ S L  P        P + + +   PE + L                +   P+ P  +
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRL-------------FPPFEESPLSPPPE 613

Query: 404 LSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAG 463
            SP++ P E   L  P   P  +P   PP  S      E + ++   +  V  LS     
Sbjct: 614 ESPLSPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSRLSPLPV--VSRLSPPPEE 668

Query: 464 TTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEP------ 517
           +     P + P +            P PEA   + P       P P   PA+ P      
Sbjct: 669 SPLSPPPEESPTS------------PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716

Query: 518 -VPHLQTPTSEPQTVARACPQSAKP 541
            +P  ++P        + CP+S  P
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGP 741



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 83/332 (25%), Positives = 108/332 (32%), Gaps = 50/332 (15%)

Query: 238  EPPAPKAPR--PKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQP 295
            EP  P AP   P +P   G        GASS   AG PG         P   P  P   P
Sbjct: 2186 EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP--DP 2243

Query: 296  SHQPLSKALESPLGLRPHLPLLMGGQAA---LKPEP-GRPGEESPAPKQEL--HQPSFPT 349
              +P   +L++ L + P  P + GG+A+   L P P G   +     K+EL    PS+  
Sbjct: 2244 FLKPRCPSLDN-LAV-PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP 2301

Query: 350  PQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAA 409
            P L  +  P +     GL    EL     F         Q       P  P   L P   
Sbjct: 2302 PNLGFVDSPSSGTHLGGL----ELKTPDVFKAPLTPRASQVE-----PQSPGLGLRPQEP 2352

Query: 410  PHEEGLLLAPSSVPS-------GTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHA 462
            P  + L  +P S P          P+  PP       +         S C + P S+   
Sbjct: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQPP------LTPRPQPPPPESCCALPPRSLP-- 2404

Query: 463  GTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQ 522
                       PF+        Q     P    P S       CP P  P    P P+  
Sbjct: 2405 ---------SDPFSRVPASPQSQSSSQSPLTPRPLSAE---AFCPSPVTPRFQSPDPY-S 2451

Query: 523  TPTSEPQTVARACPQSAKP-PSGSKSGLRTGS 553
             P S PQ+     P    P P   +   + GS
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS 2483



 Score = 37.0 bits (84), Expect = 0.070
 Identities = 96/412 (23%), Positives = 133/412 (32%), Gaps = 63/412 (15%)

Query: 185 PEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKA 244
           PE +P   P      +P   + L+       S   E PL  P      +     PP  ++
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP-----EASPLSPPFEES 552

Query: 245 PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKAL 304
           P    P+    + P       +   + PP  +  P  P P  +P  P  + S        
Sbjct: 553 PLSPPPEELPTSPPP-----EASRLSPPP--EESPMSPPPEESPMSPPPEASRL-FPPFE 604

Query: 305 ESPLGLRPH-LPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPAD 363
           ESPL   P   PL    +A+    P      SP P++    P     +LSPLP+      
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV------ 658

Query: 364 YNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVP 423
            + L   PE                        P+ P  + SP + P E   L  P   P
Sbjct: 659 VSRLSPPPE----------------------ESPLSPPPEESPTSPPPEASRLSPP---P 693

Query: 424 SGTPFQHPPWGSSRYCSSEDTGVN-GYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRS 482
             +P   PP  S      ED+ ++       +LPL            P+  P   E   S
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS 753

Query: 483 LGQLEFPL-PEAGHP---ASPAHPLLGCPVPSVP--------PAAEPVP---HLQTPTSE 527
               E  L P+A  P     P  P L C VP  P        P   P P   HL   T E
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCL-CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE 812

Query: 528 PQ-TVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRP 578
           P  +     P  +  P  S    ++   C      ++   P   K P   RP
Sbjct: 813 PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 56/238 (23%), Positives = 77/238 (32%), Gaps = 31/238 (13%)

Query: 180  SRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP 239
            S   S  PA  +       P   R  S  A     ++   + P    R  +    R    
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464

Query: 240  PAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQ----- 294
            P  K PRP+ P+V  K       G+ +  + G  G        +P+A P GP+ +     
Sbjct: 2465 PLHKPPRPQPPEVAFK------AGSLAHTSLGAGG--------FPAALPAGPAGELHAKV 2510

Query: 295  PSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSP 354
            PS QP +       G     P  M  +       G P  + P P+  L  P        P
Sbjct: 2511 PSGQPPNFVRSPGTGAFVGTPSPM--RFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGP 2568

Query: 355  LPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCG----GYSPCPMLPEGKLSPVA 408
             P  G P   N         A G+F+      G   G     Y   P+ P   L P A
Sbjct: 2569 GPTLGKPQSTN------YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 78/336 (23%), Positives = 109/336 (32%), Gaps = 65/336 (19%)

Query: 42   PESPGHLTGRRKNYPLRKRPLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPS 101
            P+SPG   G R   P   + L P  P           ++  P S  +    PP  P+P  
Sbjct: 2340 PQSPG--LGLRPQEPPPAQALAPSPPSH--------PDIFRPGSYTDPYAQPPLTPRPQP 2389

Query: 102  PAPSS----------EDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDP 151
            P P S           DP    P   +  S +   L    L  E       T R ++ DP
Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449

Query: 152  H-RSRDRDRATGGWSSSKKRPR---------LGDL-------GGGSRDLSPEPAPDEGPR 194
            + R   R ++   ++   K PR          G L       GG    L   PA +   +
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509

Query: 195  RDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNG 254
                  P  + S    AF+        P+R     A V   S +PP P+   P    +N 
Sbjct: 2510 VPSGQPPNFVRSPGTGAFVGTPS----PMRFTFPQA-VGEPSLKPPVPQPGLPPPHGINS 2564

Query: 255  KNYPKAWQGASSGEAAGPP---GWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLR 311
               P        G   G P    +        PS +P GPS   + +    +   P  + 
Sbjct: 2565 HFGP--------GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616

Query: 312  P------HLPLLMGGQAALKPEPGRPGEESPAPKQE 341
            P       LP L  G +       R G  SP  K+E
Sbjct: 2617 PPPAPDGSLPYLSHGASQ------RSGITSPVEKRE 2646


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 124/577 (21%), Positives = 192/577 (33%), Gaps = 76/577 (13%)

Query: 180  SRDLSPEPAPDEGPRRDGDPAPKRLASLNA-AAFLKLSQERELPLRLPRAHAEVDGRSTE 238
            +R   P+P+P   P     PAP+  A L A A  L  +    +P   P+       R+ E
Sbjct: 2389 ARPAPPQPSPAP-PAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKK---ARAAE 2444

Query: 239  PPAPKAPRPKWPK-----------VNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWP--- 284
                K PR    +           V      KA +     E  G  GWQ    EP     
Sbjct: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ----EPKSLLS 2500

Query: 285  --SATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQEL 342
              S  P   S +P   P  KA +  L   P   L        K       E+  A + E 
Sbjct: 2501 LGSYPPAAGSSEPK-APWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESES 2559

Query: 343  HQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLP-E 401
               S      S      + ++  G   G +    G     CG  G  C   S     P  
Sbjct: 2560 SSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG-----CGTGGRNCSAASSRAASPAS 2614

Query: 402  GKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTH 461
               S  ++        + SS  S +        SS   SS  +  +  S       S T 
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674

Query: 462  AGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHL 521
              ++C       P    G  +   L     +    A P+    G   P+  P A P    
Sbjct: 2675 EDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP---- 2730

Query: 522  QTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPR 581
              PT   Q  A+A    AK     + G+   ++      +K  R PS   +P++    P 
Sbjct: 2731 PQPTQPLQPKAQA---GAKSRPKKREGVHLPTT---KELAKRQRLPSVENRPKIAAFLPA 2784

Query: 582  RRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKT 641
            R+       W   G   ++          A +  Y+A+ R  E IR+ D  +  S  R  
Sbjct: 2785 RQL------WKWFGKPTQRR----GMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRP- 2833

Query: 642  STPYVAKISALWENPESGELMMSLLWYYRPEHLQGGR----------------------S 679
            + PY+ +I ++WE+     +++ + W+Y PE    G+                      S
Sbjct: 2834 NLPYIGRIQSMWES-WGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQKSSRSLPAALRVS 2892

Query: 680  PSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEY 716
                + ++  ++ S H D+N V  +  KC V+   +Y
Sbjct: 2893 SQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQY 2929



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 9/132 (6%)

Query: 137  TSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRD 196
            +SS + +  S +     S     ++   SSS            S   S     D     D
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682

Query: 197  GDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAP--RPKWPKVNG 254
             + AP   A  +A A L     ++     P AH+   G+ T  P P+AP  +P  P    
Sbjct: 2683 DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSP--GKKTPAPQPQAPPPQPTQPL--- 2737

Query: 255  KNYPKAWQGASS 266
               PKA  GA S
Sbjct: 2738 --QPKAQAGAKS 2747


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 128/549 (23%), Positives = 183/549 (33%), Gaps = 112/549 (20%)

Query: 100 PSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDR 159
           PS A +S +   A+  K+    +  EA          +S L   +R R      + + DR
Sbjct: 60  PSAASTSSNDSKAETVKKSAKKVKEEA----------SSPLKSNKRQREKVASDTEEADR 109

Query: 160 ATGGWSSSKK--RPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQ 217
            +   + +++  RP     G G    S     DEG     DP      + + +  +   Q
Sbjct: 110 TSSKKTKTQEISRPNSPSEGEGESSDS-RSVNDEG---SSDPKDIDQDNRSTSPSIPSPQ 165

Query: 218 ERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQG 277
           + E       + A+      +PPA +AP                 G +   ++ PPG   
Sbjct: 166 DNESD---SDSSAQQQMLQAQPPALQAPT----------------GVTPAPSSAPPG--- 203

Query: 278 CPDEPWPSATPCGPSVQPSHQPLSKAL----ESPLGLRPHLPLLMGGQAALKPEPGRPGE 333
            P  P P  TP   +V P   P +       ++P    PH  +    Q A    P RP  
Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI----QQAPALHPQRPPS 259

Query: 334 ESPAPKQELH-----------QPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLY 382
             P P    H           QPS P+    PL   G P  ++ L  GP L   G    +
Sbjct: 260 PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS-LQAGPLLQHPGPPQPF 318

Query: 383 ----CGQEGLQCGGYSPCPMLPEGKLSPVAA---------PHEEGLLLAPSSV-----PS 424
                  +G    G SP    P   L   A+         P E+ L  AP ++     P 
Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378

Query: 425 GTPFQHPPWGSSRYCSSEDTGVNGYSICGVLP----------LSVTHAGTT----CGGCP 470
            TP    P   +       +G + +S+   LP          LS  H  +         P
Sbjct: 379 TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 438

Query: 471 YKMPFAAEGCRSLGQLE---FPLPEAGHPASPAHPLLGCP-------VPSVPPAAEP--V 518
              P  +   +  G  +    P P A HP +  H +   P       VP  PP   P   
Sbjct: 439 QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 498

Query: 519 PHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSC-------RHTARSKAARRPSHPK 571
           P   TP + P T A+     A    GS +G   GSSC       +  A   A    S P 
Sbjct: 499 PSTSTPPAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTVQIKEEALDDAEEPESPPP 555

Query: 572 QPRVQRPRP 580
            PR   P P
Sbjct: 556 PPRSPSPEP 564



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 95/409 (23%), Positives = 134/409 (32%), Gaps = 77/409 (18%)

Query: 226 PRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYP--KAWQGASSGEAAGPPGWQGCPDEPW 283
           P  H  +   +     P AP    P ++G+  P   + Q     +  GPP   G P +  
Sbjct: 266 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325

Query: 284 PSATPCG--------------PSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPG 329
               P G              P+ Q + Q      E PL   P  PL M     +KP P 
Sbjct: 326 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---PPAPLAM---PHIKPPPT 379

Query: 330 RPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQ 389
            P  + PAP+   H P    P  SP  M  N      L   P L  L S   +       
Sbjct: 380 TPIPQLPAPQAHKHPPHLSGP--SPFSMNAN------LPPPPALKPLSSLSTHHPPSAHP 431

Query: 390 CGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGY 449
                P  ++P+ +  P +     GL  + +  P   P  HPP G  +         + +
Sbjct: 432 ----PPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPF 485

Query: 450 SICGVLPL--------SVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLP---------- 491
              G  P+        S   AG      P     AA G    G    PLP          
Sbjct: 486 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 545

Query: 492 EAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVA---------RACPQS---A 539
           +A  P SP       P P   P+ EP   + TP+   Q+            +C ++    
Sbjct: 546 DAEEPESP-------PPPPRSPSPEPTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYF 597

Query: 540 KPPSGSKSGLRTGSS---CRHTARSKAARRPSHPKQPRVQRPRPRRRRR 585
            P +GSK   +   +    +  A  KA       K+   +R R R R R
Sbjct: 598 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 128/549 (23%), Positives = 183/549 (33%), Gaps = 112/549 (20%)

Query: 100  PSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDR 159
            PS A +S +   A+  K+    +  EA          +S L   +R R      + + DR
Sbjct: 614  PSAASTSSNDSKAETVKKSAKKVKEEA----------SSPLKSNKRQREKVASDTEEADR 663

Query: 160  ATGGWSSSKK--RPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQ 217
             +   + +++  RP     G G    S     DEG     DP      + + +  +   Q
Sbjct: 664  TSSKKTKTQEISRPNSPSEGEGESSDS-RSVNDEG---SSDPKDIDQDNRSTSPSIPSPQ 719

Query: 218  ERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQG 277
            + E       + A+      +PPA +AP                 G +   ++ PPG   
Sbjct: 720  DNESD---SDSSAQQQMLQAQPPALQAPT----------------GVTPAPSSAPPG--- 757

Query: 278  CPDEPWPSATPCGPSVQPSHQPLSKAL----ESPLGLRPHLPLLMGGQAALKPEPGRPGE 333
             P  P P  TP   +V P   P +       ++P    PH  +    Q A    P RP  
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI----QQAPALHPQRPPS 813

Query: 334  ESPAPKQELH-----------QPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLY 382
              P P    H           QPS P+    PL   G P  ++ L  GP L   G    +
Sbjct: 814  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS-LQAGPLLQHPGPPQPF 872

Query: 383  ----CGQEGLQCGGYSPCPMLPEGKLSPVAA---------PHEEGLLLAPSSV-----PS 424
                   +G    G SP    P   L   A+         P E+ L  AP ++     P 
Sbjct: 873  GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 425  GTPFQHPPWGSSRYCSSEDTGVNGYSICGVLP----------LSVTHAGTT----CGGCP 470
             TP    P   +       +G + +S+   LP          LS  H  +         P
Sbjct: 933  TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992

Query: 471  YKMPFAAEGCRSLGQLE---FPLPEAGHPASPAHPLLGCP-------VPSVPPAAEP--V 518
               P  +   +  G  +    P P A HP +  H +   P       VP  PP   P   
Sbjct: 993  QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 1052

Query: 519  PHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSC-------RHTARSKAARRPSHPK 571
            P   TP + P T A+     A    GS +G   GSSC       +  A   A    S P 
Sbjct: 1053 PSTSTPPAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTVQIKEEALDDAEEPESPPP 1109

Query: 572  QPRVQRPRP 580
             PR   P P
Sbjct: 1110 PPRSPSPEP 1118



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 95/409 (23%), Positives = 134/409 (32%), Gaps = 77/409 (18%)

Query: 226  PRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYP--KAWQGASSGEAAGPPGWQGCPDEPW 283
            P  H  +   +     P AP    P ++G+  P   + Q     +  GPP   G P +  
Sbjct: 820  PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879

Query: 284  PSATPCG--------------PSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPG 329
                P G              P+ Q + Q      E PL   P  PL M     +KP P 
Sbjct: 880  QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---PPAPLAM---PHIKPPPT 933

Query: 330  RPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQ 389
             P  + PAP+   H P    P  SP  M  N      L   P L  L S   +       
Sbjct: 934  TPIPQLPAPQAHKHPPHLSGP--SPFSMNAN------LPPPPALKPLSSLSTHHPPSAHP 985

Query: 390  CGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGY 449
                 P  ++P+ +  P +     GL  + +  P   P  HPP G  +         + +
Sbjct: 986  ----PPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPF 1039

Query: 450  SICGVLPL--------SVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLP---------- 491
               G  P+        S   AG      P     AA G    G    PLP          
Sbjct: 1040 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 1099

Query: 492  EAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVA---------RACPQS---A 539
            +A  P SP       P P   P+ EP   + TP+   Q+            +C ++    
Sbjct: 1100 DAEEPESP-------PPPPRSPSPEPTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYF 1151

Query: 540  KPPSGSKSGLRTGSS---CRHTARSKAARRPSHPKQPRVQRPRPRRRRR 585
             P +GSK   +   +    +  A  KA       K+   +R R R R R
Sbjct: 1152 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 128/549 (23%), Positives = 183/549 (33%), Gaps = 112/549 (20%)

Query: 100  PSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDR 159
            PS A +S +   A+  K+    +  EA          +S L   +R R      + + DR
Sbjct: 614  PSAASTSSNDSKAETVKKSAKKVKEEA----------SSPLKSNKRQREKVASDTEEADR 663

Query: 160  ATGGWSSSKK--RPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQ 217
             +   + +++  RP     G G    S     DEG     DP      + + +  +   Q
Sbjct: 664  TSSKKTKTQEISRPNSPSEGEGESSDS-RSVNDEG---SSDPKDIDQDNRSTSPSIPSPQ 719

Query: 218  ERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQG 277
            + E       + A+      +PPA +AP                 G +   ++ PPG   
Sbjct: 720  DNESD---SDSSAQQQMLQAQPPALQAPT----------------GVTPAPSSAPPG--- 757

Query: 278  CPDEPWPSATPCGPSVQPSHQPLSKAL----ESPLGLRPHLPLLMGGQAALKPEPGRPGE 333
             P  P P  TP   +V P   P +       ++P    PH  +    Q A    P RP  
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI----QQAPALHPQRPPS 813

Query: 334  ESPAPKQELH-----------QPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLY 382
              P P    H           QPS P+    PL   G P  ++ L  GP L   G    +
Sbjct: 814  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS-LQAGPLLQHPGPPQPF 872

Query: 383  ----CGQEGLQCGGYSPCPMLPEGKLSPVAA---------PHEEGLLLAPSSV-----PS 424
                   +G    G SP    P   L   A+         P E+ L  AP ++     P 
Sbjct: 873  GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 425  GTPFQHPPWGSSRYCSSEDTGVNGYSICGVLP----------LSVTHAGTT----CGGCP 470
             TP    P   +       +G + +S+   LP          LS  H  +         P
Sbjct: 933  TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992

Query: 471  YKMPFAAEGCRSLGQLE---FPLPEAGHPASPAHPLLGCP-------VPSVPPAAEP--V 518
               P  +   +  G  +    P P A HP +  H +   P       VP  PP   P   
Sbjct: 993  QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 1052

Query: 519  PHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSC-------RHTARSKAARRPSHPK 571
            P   TP + P T A+     A    GS +G   GSSC       +  A   A    S P 
Sbjct: 1053 PSTSTPPAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTVQIKEEALDDAEEPESPPP 1109

Query: 572  QPRVQRPRP 580
             PR   P P
Sbjct: 1110 PPRSPSPEP 1118



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 95/409 (23%), Positives = 134/409 (32%), Gaps = 77/409 (18%)

Query: 226  PRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYP--KAWQGASSGEAAGPPGWQGCPDEPW 283
            P  H  +   +     P AP    P ++G+  P   + Q     +  GPP   G P +  
Sbjct: 820  PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879

Query: 284  PSATPCG--------------PSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPG 329
                P G              P+ Q + Q      E PL   P  PL M     +KP P 
Sbjct: 880  QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---PPAPLAM---PHIKPPPT 933

Query: 330  RPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQ 389
             P  + PAP+   H P    P  SP  M  N      L   P L  L S   +       
Sbjct: 934  TPIPQLPAPQAHKHPPHLSGP--SPFSMNAN------LPPPPALKPLSSLSTHHPPSAHP 985

Query: 390  CGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGY 449
                 P  ++P+ +  P +     GL  + +  P   P  HPP G  +         + +
Sbjct: 986  ----PPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--PPASHPPTGLHQVAPQPPFAQHPF 1039

Query: 450  SICGVLPL--------SVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLP---------- 491
               G  P+        S   AG      P     AA G    G    PLP          
Sbjct: 1040 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 1099

Query: 492  EAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVA---------RACPQS---A 539
            +A  P SP       P P   P+ EP   + TP+   Q+            +C ++    
Sbjct: 1100 DAEEPESP-------PPPPRSPSPEPTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYF 1151

Query: 540  KPPSGSKSGLRTGSS---CRHTARSKAARRPSHPKQPRVQRPRPRRRRR 585
             P +GSK   +   +    +  A  KA       K+   +R R R R R
Sbjct: 1152 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 134/559 (23%), Positives = 175/559 (31%), Gaps = 92/559 (16%)

Query: 33   GVEGVEPGMPESPGHLTGRRKNYP-----LRKRPLVPEKPKACKVLLTRLENVAGPRSAD 87
            G    +P  P  PG  +G     P       K P +P    A  + L +    +GP  A 
Sbjct: 983  GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQ----SGPHQAA 1038

Query: 88   EADELPPDLPKPPSPAPSSEDP-GLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRS 146
                 PP  P PP PAP+SE   GL  P             ++  L R         ++ 
Sbjct: 1039 P----PPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKL 1094

Query: 147  RAGDPHRSRDRDRA-------------TGGWSSSKKRPRLGDLGGGSRDLS---PEPAPD 190
             A +     D D+A                 SS + RP L  LG    D+    P P PD
Sbjct: 1095 YAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLG----DIDFCPPNPGPD 1150

Query: 191  EGPR----------RDGDPAPK-----RLASLNAAAFLKLSQERELPLRLPRAHAEVDGR 235
             GPR          RDG P P+     R   +   A    +       + PR      GR
Sbjct: 1151 -GPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGR 1209

Query: 236  STEPPAPKAPRPKWPKVNGKNYPKAWQ--GASSGEAAGPPGWQGCPDEPWPSATPCGPSV 293
              E        P  P     + PKA +  G SSG+A                        
Sbjct: 1210 KAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKE 1269

Query: 294  QPSHQPLSKA------LESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSF 347
                QP  K+      L+     + H PL    QA L P    P    P+      QP  
Sbjct: 1270 VEEKQPEMKSGFMASFLDFLKSGKRHPPLY---QAGLTPPLSPPKSVPPSVPARGLQPQP 1326

Query: 348  PTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPV 407
            P     P P P       G     E             EGL  G  SPC  L        
Sbjct: 1327 PATPAVPHPPPSGAFGLGGALEAAE------------SEGLGLGCPSPCKRL-------- 1366

Query: 408  AAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCG 467
                +E L     ++PS +  +      +R    +++  +  S     PL+     +T  
Sbjct: 1367 ----DEELKRNLETLPSFSSDEEDSVAKNR--DLQESISSAISALDDPPLAGPKDTSTPD 1420

Query: 468  GCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLL-GCPVPSVPPAAEPVPHLQTPTS 526
            G P     A  G   L      LP A    +P  PLL   P P+ PPA  P P    P  
Sbjct: 1421 GPPLAPAAAVPGPPPLP----GLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPP 1476

Query: 527  EPQTVARACPQSAKPPSGS 545
             PQ    + P    P   S
Sbjct: 1477 PPQPALPSPPPLVAPTPSS 1495



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 80/296 (27%), Positives = 99/296 (33%), Gaps = 60/296 (20%)

Query: 67   PKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAP---------SSEDPGLAQPRKR 117
            P A KV +  LE    P + D A + PP  P PP P P            +P    PR R
Sbjct: 814  PSASKVGVHLLE----PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869

Query: 118  RLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLG 177
               SL+       LL               A +P      D   G  +S  K P      
Sbjct: 870  PEESLDPPGAMQELL--------------GALEPLPPAPGDTGVGPPNSEGKDP-----A 910

Query: 178  GGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRST 237
            G  R  SP+          G  AP R   L +  F     + E     P       G + 
Sbjct: 911  GAYRSPSPQ----------GTKAP-RFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAA 959

Query: 238  EPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSA--TPCGPSVQP 295
            +      P    P+  G   PKA  G   G  A  P    CP     +   TP G  + P
Sbjct: 960  DDYGKAGP----PEDEGD--PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETP-GLGLDP 1012

Query: 296  SHQPLSKALESPLGLRPHLPLLMGG--QAALKPEPGRPGEESPA--PKQELHQPSF 347
            +  P    L S +   P L L+  G  QAA  P P  P   +PA  PK  L  P F
Sbjct: 1013 NKPP---ELPSTVNAEP-LGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIF 1064



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 19/137 (13%)

Query: 222  PLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDE 281
            PL  P+  +  DG    P AP A  P  P + G   P A    S+G    P   +  P  
Sbjct: 1409 PLAGPKDTSTPDG---PPLAPAAAVPGPPPLPG--LPSA---NSNGTPEPPLLEEKPPPT 1460

Query: 282  PWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQE 341
            P P+ TP  P   P   P   AL SP       P L+    +  P P  P    P P   
Sbjct: 1461 PPPAPTP-QPQPPPPPPPPQPALPSP-------PPLVAPTPSSPPPPPLP---PPPPPAM 1509

Query: 342  LHQPSFPTPQLSPLPMP 358
               P  P P  +PL  P
Sbjct: 1510 PSPPPPPPPAAAPLAAP 1526



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 24/98 (24%), Positives = 33/98 (33%)

Query: 264  ASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAA 323
            +S+  A   P   G  D   P   P  P+      P    L S        P L+  +  
Sbjct: 1399 SSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP 1458

Query: 324  LKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNP 361
              P P    +  P P     QP+ P+P     P P +P
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSP 1496



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 73/319 (22%), Positives = 104/319 (32%), Gaps = 57/319 (17%)

Query: 12   LSSGLTGRREPLQMEDSNMEQGVEGVEPG-MPESPGHLTGRRKNYPLRKRPLVPEKPKAC 70
            L S LT  RE ++ +   +E+    ++ G M      L   +++ PL +  L P      
Sbjct: 1254 LDSSLT--REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP----- 1306

Query: 71   KVLLTRLENVAGPRSADEADELPPDLPKPPSPAPS-------------SEDPGLA--QPR 115
               L+  ++V     A      PP  P  P P PS             SE  GL    P 
Sbjct: 1307 ---LSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPC 1363

Query: 116  KRRLASL--NAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRL 173
            KR    L  N E L +   + ED+ +             ++RD   +     S+   P L
Sbjct: 1364 KRLDEELKRNLETLPSFSSDEEDSVA-------------KNRDLQESISSAISALDDPPL 1410

Query: 174  GDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASL-----NAAAFLKLSQERELPLRLPRA 228
                 G +D S    P   P     P P  L  L     N      L +E+  P   P  
Sbjct: 1411 A----GPKDTSTPDGPPLAPAA-AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465

Query: 229  HAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATP 288
              +       PP P  P+P  P       P     +       PP     P  P P    
Sbjct: 1466 TPQPQ----PPPPPPPPQPALPSPPPLVAPTP--SSPPPPPLPPPPPPAMPSPPPPPPPA 1519

Query: 289  CGPSVQPSHQPLSKALESP 307
              P   P  +P + + E P
Sbjct: 1520 AAPLAAPPEEPAAPSPEDP 1538



 Score = 30.8 bits (68), Expect = 5.0
 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 93   PPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNL----LLEREDTSSLAGTRRSRA 148
            PP +P PP P P +  P  A P +    S     L +     L ++++T+++ G     A
Sbjct: 1506 PPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEA 1565

Query: 149  GD 150
            G+
Sbjct: 1566 GE 1567


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 121/479 (25%), Positives = 162/479 (33%), Gaps = 102/479 (21%)

Query: 239 PPAPKAPRP-----KWPKVNG------------------KNYPKAWQGA--SSGEAAGPP 273
           PPA  APRP      +P ++G                   N    W+ A   +G   G P
Sbjct: 465 PPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAP 524

Query: 274 GWQGCPDEPWPSATPCG--------PSVQPSHQPLSKALESPLGLR------PHLPLLMG 319
            WQ     P P A P          PSV P     S ++ S   +R      P  PL   
Sbjct: 525 AWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPN 584

Query: 320 GQAALKPEPGRPGEESPAPKQELHQ--------PSFPTPQLSPLPMPGNPADYNGLCVGP 371
               L  +PG P  ++P    E+ Q        P FP P+  P P   + A  + L  G 
Sbjct: 585 DWDPL--DPGVPAPQAPQAPSEVPQLVSETWASPLFPAPR--PFPAQSS-ASGSFLLSGW 639

Query: 372 ELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPV-AAPHEEGLLLAPSSVPSGTPFQH 430
           +    G+     G      G     P + E +     ++P E+      SS   G P + 
Sbjct: 640 DPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGED------SSSLGGGPSRR 693

Query: 431 PPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCP-YKMPFAAEGCRSL----GQ 485
            P      CS E         C  LPL    A    GG P    P   E   SL    G 
Sbjct: 694 GPL-PCPLCSRE-------GACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGS 745

Query: 486 L-EFPL-PEAGHPASPAHPLLGCPVPSVP---PAAEPVPHLQTPTSEPQTVARACPQS-- 538
           L + P+ P A  P     PL+G   P  P   P   P P    P +     A   P S  
Sbjct: 746 LADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAV 805

Query: 539 AKPPSG-SKSGLRTGSSCRHT---------------ARSKAARRPSHPKQPRVQRPRPRR 582
           A P SG S  G + G S   T               A  +   RP  P +P    P P  
Sbjct: 806 ASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEP----PDPGA 861

Query: 583 RRRRRTNGWVPVGAACEKAVYVLD-EPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRK 640
            R     G +P+    EK  +V+    E  +    + V R+   +  +     ++GPRK
Sbjct: 862 PRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRN--LLGEKGATARETGPRK 918



 Score = 36.6 bits (83), Expect = 0.092
 Identities = 75/303 (24%), Positives = 108/303 (35%), Gaps = 67/303 (22%)

Query: 78   ENVAGPRSADEADELPPDLPKPPSPAPSSEDPG---LAQPRKR-----------RLASLN 123
            E V  PR+       PP+ P P +P P   DPG   L  PR++            L SL 
Sbjct: 845  EGVPRPRA-------PPEPPDPGAPRP-PPDPGPLPLPGPREKPTFVVQVSTEQLLMSLR 896

Query: 124  AEALNNLLLEREDTSSLAGTRRSRAGDPHRSR----DRDRATGGWSSSKKRPRLGDLGGG 179
             +   NLL E+  T+   G R++  G  +R +    +RD    G  + K+ P L     G
Sbjct: 897  EDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLG--NGKQAPSLSLPVNG 954

Query: 180  SRDLS---------PEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQEREL---PLRLPR 227
               L           E A + G    G P  +     N        +E+ L    LR P 
Sbjct: 955  VTVLENGDQRAPGIEEKAAENGAL--GSPEREEKVLENGELTPPRREEKALENGELRSPE 1012

Query: 228  AHAE--VDGRSTEPPAPKAPRPKWPKVNGKNYPK-AWQGASSGEAAGPPGWQGCPDE--P 282
            A  +  V+G  T P +      K  +  G  +P+   +   +G    P  W+  P+   P
Sbjct: 1013 AGEKVLVNGGLTPPKS----EDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGP 1068

Query: 283  WPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQEL 342
             P+     P       P   A+ S            GG+ A       PG   PAPK   
Sbjct: 1069 APTIGEPAPETSLERAPAPSAVVSSRN---------GGETA-------PGPLGPAPKNGT 1112

Query: 343  HQP 345
             +P
Sbjct: 1113 LEP 1115



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 46/199 (23%), Positives = 60/199 (30%), Gaps = 54/199 (27%)

Query: 82   GPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLA 141
            GP S  +A     D  +P  P P    P  AQPR+   A                     
Sbjct: 1155 GPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPA--------------------- 1193

Query: 142  GTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAP 201
                     P R+R      G   +   R       GG   LS +  P + P R G   P
Sbjct: 1194 ---------PPRARPEVAPEGEPGAPDSR------AGGDTALSGDGDPPK-PERKGPEMP 1237

Query: 202  KRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP-PAPKAPRPKWPKVNGKNYPKA 260
            +    L            ++  RL R    +   +  P P P   RP W           
Sbjct: 1238 RLFLDLGPPQ----GNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPW----------- 1282

Query: 261  WQGASSGEAAGPPGWQGCP 279
             +GA +G A G  G  G P
Sbjct: 1283 -EGADAGAAGGEAGGAGAP 1300


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 112/476 (23%), Positives = 162/476 (34%), Gaps = 85/476 (17%)

Query: 119 LASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGG 178
           LA  +A+ LN  + + E  S +AG  +   G P +  ++ +   G  S   +P+     G
Sbjct: 11  LALSSAQNLNEDVSQEESPSLIAGNPQ---GAPPQGGNKPQ---GPPSPPGKPQGPPPQG 64

Query: 179 GSRDLSPEPAPDE--------GPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHA 230
           G++   P P P +        G +  G P P +            S+    P   P+   
Sbjct: 65  GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG--DKSRSPRSPPGKPQGPP 122

Query: 231 EVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCG 290
              G   + P P   +P+ P   G N P+           GPP          P   P G
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-----------GPP----------PPGKPQG 161

Query: 291 PSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTP 350
           P  Q  ++  S++  SP G +P  P   GG     P P  PG+    P Q  ++P  P P
Sbjct: 162 PPPQGDNK--SRSSRSPPG-KPQGPPPQGGNQPQGPPP-PPGKPQGPPPQGGNKPQGPPP 217

Query: 351 QLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAP 410
              P   P    + +     P     G       Q G Q  G  P P  P+G       P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGP----PPQGGNQPQGPPPPPGKPQG-------P 266

Query: 411 HEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCP 470
             +G        P G P   PP G S+  SS              P          GG  
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS------------PPGKPQGPPPQGGNQ 314

Query: 471 YKMPFAAEGCRSLGQLEFPLPEAGH-PASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQ 529
            + P         G+ + P P+ G+ P  P  P  G P    P         ++P  +PQ
Sbjct: 315 PQGPPPPP-----GKPQGPPPQGGNKPQGPPPP--GKPQGPPPQGGSKSRSARSPPGKPQ 367

Query: 530 TVARA---CPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRR 582
              +     PQ   PP+G               ++  A +P  P +P  Q  RP R
Sbjct: 368 GPPQQEGNNPQGPPPPAGGNP---------QQPQAPPAGQPQGPPRP-PQGGRPSR 413


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 123/525 (23%), Positives = 173/525 (32%), Gaps = 76/525 (14%)

Query: 82  GPR-SADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSL 140
           GPR S   A E     P P +    S   GL +P  R L+S    +   L        S 
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS----SATPLSSPARSGPSA 259

Query: 141 AGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPA 200
            GT R+ A   H S+ + +        +  P   D       LS  P     P   G  A
Sbjct: 260 RGTPRAPA---HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP--SGTKA 314

Query: 201 PKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPR-----PKWPKVNGK 255
                  NAA  L  +     PL  P   A        PP+P AP      P  P     
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLA--------PPSPSAPPSLQTLPSPPATPPS 366

Query: 256 NYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLS-KALESPLGLRPHL 314
             P +    ++     PP  Q  P    P +    PS+Q    PL+  +L++   L    
Sbjct: 367 QAPPSM---TTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGS-- 420

Query: 315 PLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGL--CVGP- 371
           P L    + L   P +      +P +    P    P  +PL +P +P     L   V P 
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480

Query: 372 -------ELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAP--SSV 422
                   L AL S   +  Q  L        P+  +  L+P +       L  P   ++
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLS--SLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 423 PSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGC-- 480
           PS  P   PP  ++                   PL+  H  T    CP   P  A     
Sbjct: 539 PSLAP---PPLQTAS-----------------APLTTPHLETP--PCPAPCPLQAPPSPL 576

Query: 481 -----RSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARAC 535
                 +   +  P P+A  PA  + PL G P P + P A P P      + P   A   
Sbjct: 577 TTPPPETPSSIATPPPQAP-PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635

Query: 536 PQSAKP--PSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRP 578
           P ++ P  P  + S     +   H  ++  +  PS P Q     P
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 138/515 (26%), Positives = 171/515 (33%), Gaps = 86/515 (16%)

Query: 61  PLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSED--PGLAQPRKRR 118
           PL P  P A   L T     A P S     + PP +  PP  AP S    P +  P    
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPS-----QAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396

Query: 119 LASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGG 178
             SL A      L   + T+SL        G P       +AT  + +   R     L  
Sbjct: 397 SPSLQAPPSPLALSSLQATTSL--------GSPTL-----QATHSFLTMSPRQTQASLTS 443

Query: 179 GSRDLS--PEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRS 236
            SR  S  P+  P + P     PA   L +  + A   LS     PL +    A     S
Sbjct: 444 PSRPASTPPDSPPLQAPL--SLPASPPLQTSLSPAVSPLSS----PLTIHPLQALSSLAS 497

Query: 237 TEPPAPKAPRPKWP-KVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQP 295
             P AP +     P +      P + Q         P      P E  PS  P  P +Q 
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQ-------TPPASLTTPPLENLPSLAP--PPLQT 548

Query: 296 SHQPLSKA-LESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQ---ELHQP---SFP 348
           +  PL+   LE+P    P  PL         P P  P   +  P Q    L  P     P
Sbjct: 549 ASAPLTTPHLETPPCPAP-CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607

Query: 349 TPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVA 408
           +P LSPL  P   A        P   AL           LQ     P        LSP+A
Sbjct: 608 SPPLSPLATPPPQA--------PPXLAL---------PPLQAPPSPPA----SPPLSPLA 646

Query: 409 APHEEG-------LLLAPSSVPSGTPFQHP--PWGSSRYCSSEDTGVNGYSICGVLPLSV 459
            P  +        LL AP S P   P Q P  P  S     S              PL V
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706

Query: 460 THAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLL---GCPVPSVPPAAE 516
             +       P   P A    ++   L  P P    P+ PA P +     P P VPP   
Sbjct: 707 PPSPP---ASPPMSPSATPPPQAPPPLAAP-PLQVPPSPPASPPMSPSATPPPRVPPLL- 761

Query: 517 PVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRT 551
             P LQ P S P ++  +    AKPP  +   L T
Sbjct: 762 AAPPLQVPPSPPASLPMS--PLAKPPPQAPPALAT 794



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 93/374 (24%), Positives = 117/374 (31%), Gaps = 95/374 (25%)

Query: 239  PPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQ 298
            PP+P A  P  P       P+A         A PP     P  P P++ P  PS  P  +
Sbjct: 707  PPSPPASPPMSPSATPP--PQA-----PPPLAAPP--LQVPPSP-PASPPMSPSATPPPR 756

Query: 299  PLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMP 358
                    PL + P  P  +      KP P  P             P+  TP L  LP P
Sbjct: 757  VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP-------------PALATPPLQALPSP 803

Query: 359  GNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEG---- 414
              PA + G                          +SP   LP   +SP+A P  +     
Sbjct: 804  --PASFPGQ-----------------------APFSPSASLP---MSPLATPPPQAPPVL 835

Query: 415  ---LLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVL----------PLSVTH 461
               LL  P S P+    Q P    +      DT V+G  +   L            S T 
Sbjct: 836  AAPLLQVPPSPPASPTLQAPRRPPT---PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892

Query: 462  AGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASP--------AHPLLGCPVPSVPP 513
            +G    G         E  R         PE G  ASP         HP      P+ P 
Sbjct: 893  SGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948

Query: 514  A---AEPVPHLQTPTSEPQTVARAC-------PQSAKP-PSGSKSGLRTGSSCRHTARSK 562
            A   A   P    P + P +    C       P+SA P P     G   G+S    A   
Sbjct: 949  AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008

Query: 563  AARRPSH-PKQPRV 575
             A   S  PKQ R+
Sbjct: 1009 GAGASSRSPKQARL 1022



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 89/377 (23%), Positives = 114/377 (30%), Gaps = 75/377 (19%)

Query: 189 PDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVD---GRSTEPPAPKAP 245
           P E P     P P+   +L +     L      PL  P   A           PP+P A 
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639

Query: 246 RPKWPKVN-GKNYPKAWQGASSGEAAGPPGWQG--CPDEPWPSATPCGPSVQPSHQPLSK 302
            P  P        P A           PP       P  P P++ P  PS  P  Q    
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPS 698

Query: 303 ALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPA 362
               PL + P  P       +  P P  P   +  P Q    P   +P +SP   P  P 
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-ASPPMSPSATP--PP 755

Query: 363 DYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSV 422
               L   P L                    SP   LP   +SP+A P  +    AP ++
Sbjct: 756 RVPPLLAAPPLQV----------------PPSPPASLP---MSPLAKPPPQ----APPAL 792

Query: 423 PSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRS 482
            +  P Q  P   + +                               P + PF+      
Sbjct: 793 AT-PPLQALPSPPASF-------------------------------PGQAPFSPSASLP 820

Query: 483 LGQLEFPLPEAGHPASPAHPLLGCPVPSVP-------PAAEPVPHLQTPTSEPQTVARAC 535
           +  L  P P+A  P   A PLL  P PS P       P   P P   T  S P+      
Sbjct: 821 MSPLATPPPQA--PPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877

Query: 536 PQSAKPPSGSKSGLRTG 552
           P    PPS S S   +G
Sbjct: 878 PGPPPPPSRSPSSTLSG 894


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 95/365 (26%), Positives = 130/365 (35%), Gaps = 73/365 (20%)

Query: 93  PPDLPKPPSP--APSSEDPGLAQPRKRRLASL---NAEALNNLLLEREDTSSLAGTRRSR 147
           PP LP PP P  AP    P  A P     +SL   + +  + LL + +      GTR  +
Sbjct: 8   PPPLPPPPPPLGAPPPPPPS-APPVSTDTSSLRRADPKGRSALLADIQQ-----GTRLRK 61

Query: 148 AGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASL 207
                 ++  DR+     SSK   + G   GGS +              G   P  L  L
Sbjct: 62  V-----TQINDRSAPQIESSKGTNKEG---GGSANTR------------GASTPPTLGDL 101

Query: 208 NAAAFLKLSQERELPLRLPRAHAEVDGRST-EPPAPKAPRPKWPK--VNGKNYPKAWQ-- 262
            A  F         P+  P    +V G  T + P  +AP P+ P   ++G   P A    
Sbjct: 102 FAGGF---------PVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRL 152

Query: 263 ---GASSGEAAGPPGWQGCPDEPWPSATPCGPSVQP---SHQPLSKALESPLG--LRPHL 314
                + G A   P     P  P P+  P  P + P   S  P+   L SP G   + +L
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212

Query: 315 PLLMGGQAALKPEPGRPGEESPAP--KQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPE 372
           P++        P P  P   +P P     +       PQL+PL +P  P         P 
Sbjct: 213 PVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP---------PP 263

Query: 373 LTALGSFYLYCGQEGLQCGGYSPC-----PMLPEGKLSPVAAPHEEGLLLAPSSVPSGTP 427
           L  L      CG  GL+    SP      P  P   L P A+      L AP      + 
Sbjct: 264 LPLLPP----CGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS 319

Query: 428 FQHPP 432
            + PP
Sbjct: 320 SETPP 324



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 50/195 (25%), Positives = 68/195 (34%), Gaps = 30/195 (15%)

Query: 174 GDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFL--KLSQERELPLRLPRAHAE 231
           G L  G+  +   P P   P     P P     L  A+ L  K  + +  PL LP     
Sbjct: 205 GPLTKGNLPVVAPPVPC-APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLP----- 258

Query: 232 VDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
                  PP P  P   +P +      KA   + + +A  PP     P  P P    C P
Sbjct: 259 ----PIPPPLPLLPPCGYPGL------KAEPASPAQDAQEPPA----PPPPLPPYASCSP 304

Query: 292 SVQPSHQPL---SKALESPLGLRPHLPLLMG-----GQAALKPEPGRPGEESPAPKQELH 343
                  PL   + + E+P  L P  P         G  AL   P  PG +    K+   
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364

Query: 344 QPSFPTPQLSPLPMP 358
           +P     +L+P P P
Sbjct: 365 RPGAGGGKLNPPPAP 379


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 129/498 (25%), Positives = 163/498 (32%), Gaps = 130/498 (26%)

Query: 57   LRKRPLVPEKPKACKVLLTRLENVAGPRSADEADEL---PPDL---PK------------ 98
            L+K+P  P +P A K LL R E      + D  +EL   PPD+   P+            
Sbjct: 712  LKKKP--PPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPL 769

Query: 99   --PPSPAPSSEDPG---LAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHR 153
              PPSP PSS  PG   L+ P      S   + +                 + RA  PH 
Sbjct: 770  HFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI-----------------QPRAPGPH- 811

Query: 154  SRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEG----PRRDGDPAPKRLASLNA 209
            +         + +    P LG        L P  +P  G    P     PAP  +A L +
Sbjct: 812  AMPVAPGPALYPAPAYTPELG--------LVPRSSPQHGVVSSPYVGVGPAPP-VAGLPS 862

Query: 210  AAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEA 269
            A   + S   EL + +  A   VD      P+  APRP                  +   
Sbjct: 863  APPPQFSGP-ELAMAVRPATTTVDSIQAPIPSHTAPRP------------------NPTP 903

Query: 270  AGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPL---LMGGQAALKP 326
            A PP              PC P   P  QPL      P G +  +P       G  A  P
Sbjct: 904  APPP--------------PCFPVPPP--QPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP 947

Query: 327  EPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQE 386
             P    +  P P+    Q   P P   PLP+  +P  +      P L    S Y Y  Q 
Sbjct: 948  APRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQ-HPHLFPPQA--PGLLPPQSPYPYAPQP 1004

Query: 387  GLQCGGYSPCPMLPEGKLSPVA--APHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDT 444
            G+   G  P P+  +    P     P   G L  PS  P   P  HPP       S+   
Sbjct: 1005 GVL--GQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP--HPPLAYGPAPSTRPM 1060

Query: 445  GVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLL 504
            G                        P   P    G  S GQ     P      SPA    
Sbjct: 1061 G------------------------PQAAPLTIRGPSSAGQ---STPSPHLVPSPAPSPG 1093

Query: 505  GCPVPSVPPAAEPVPHLQ 522
              PVP  PPAAEP P L+
Sbjct: 1094 PGPVPPRPPAAEPPPCLR 1111


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 100/378 (26%), Positives = 124/378 (32%), Gaps = 54/378 (14%)

Query: 197  GDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKN 256
            G P P  +   +    LK     +    LP    E  G   EP  P  P P  P + G  
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 257  YPKAWQGASS-GEAAGPPGWQGCPDEPWPSAT--------PCGPSVQPSHQPLSKALESP 307
              K   G       +GP G+QG P +P             P GP   P   P    L  P
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPG-LPGQPGLIGP 1022

Query: 308  LGLR----------------PHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQ 351
             GL+                P  P  + GQ      PG+ G++       +  P  P P+
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 352  LSP-LP-MPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAA 409
              P LP  PGNP    G    P L  L       GQ GL     +P P  P+G   P   
Sbjct: 1083 GEPGLPGYPGNPG-IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP--- 1138

Query: 410  PHEEGLLLAPSSV-PSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGG 468
            P   GL   P  V   G P Q  P G       +  G+ G             AG    G
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD--GIPG------------PAGQK--G 1182

Query: 469  CPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEP 528
             P +  F   G   L  L     + G P  P +P  G P P   P     P +Q P   P
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 529  QTVARAC--PQSAKPPSG 544
             +   A   P+    P G
Sbjct: 1241 GSPGPALEGPKGNPGPQG 1258



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 86/299 (28%), Positives = 107/299 (35%), Gaps = 53/299 (17%)

Query: 174  GDLGGGSRDLSPEPAPDEG-PRRDGDPAPK-RLASLNAAAFLKLSQERELPLRLPRAHAE 231
            G +GGG     P P  ++G P +DG P P  +        F         P  LP    +
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG-----PPGLPGLSGQ 1203

Query: 232  VD--GRSTEPPAPKAPRPK-------WPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEP 282
                G    P  P  P PK       +P V G   P    G +     G PG QG P  P
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263

Query: 283  WPSA-----TPCGPSVQPSHQPLSKALESP--LGLRPHLPLLMG--GQAALKPEPGRPGE 333
             P+       P GP   P +  +     +P   GL P LP L G  G   L+  PGRPG 
Sbjct: 1264 GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL-PGLPGLKGDQGPPGLQGNPGRPGL 1322

Query: 334  ESPAPKQEL-HQPSFPTPQLSPLPMPGN--PADYNGLCVGPELTALGSFYLYCGQEGLQC 390
                    L   P FP  +  P  +PG+  P    GL +GP            G  GL  
Sbjct: 1323 NGMKGDPGLPGVPGFPGMK-GPSGVPGSAGPEGEPGL-IGPP-----------GPPGLP- 1368

Query: 391  GGYSPCPMLPEGKLSPVAAPHEEGLLLAPS-SVPSGTPFQHPPWGSSRYCSSEDTGVNG 448
             G S   ++ +G   P   P + GL   P    P G P    P G        D G NG
Sbjct: 1369 -GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG--------DPGRNG 1418



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 42/132 (31%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 240 PAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQP 299
           P P  P P  P   G   PK  +G       GPPG  G    P P     GP+ QP   P
Sbjct: 756 PGPPGP-PGLPGFKGALGPKGDRGFPG--PPGPPGRTGLDGLPGPKGD-VGPNGQPG--P 809

Query: 300 LSKALESPLGLR--PHLPLLMG--GQAAL------KPEPGRPGEESPAPKQELHQPSFPT 349
           +       +G++  P  P + G  GQ  L      K +PG PG + P P  E   P  P 
Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 350 PQLSPLPMPGNP 361
               P+  PG+P
Sbjct: 870 AP-GPIGPPGSP 880



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 66/247 (26%), Positives = 87/247 (35%), Gaps = 38/247 (15%)

Query: 179  GSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTE 238
            G   +  +P     P + GD     ++S+          E  LP   P  +  + G   +
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYP-GNPGIKGSVGD 1102

Query: 239  PPAPKAP-------RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
            P  P  P       +P  P   G   P   +G S     GPPG  G P EP P      P
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-----GPPGNPGLPGEPGPVGGGGHP 1157

Query: 292  SVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFP--T 349
              QP   P  K      G+         G A  K EPG+PG  +P P      P  P  +
Sbjct: 1158 G-QPG-PPGEKGKPGQDGIP--------GPAGQKGEPGQPGFGNPGP------PGLPGLS 1201

Query: 350  PQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPML--PEGKLSPV 407
             Q     +PG P   N    GP+      F+ + G +G      SP P L  P+G   P 
Sbjct: 1202 GQKGDGGLPGIPG--NPGLPGPK--GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 408  AAPHEEG 414
              P   G
Sbjct: 1258 GPPGRPG 1264



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 28/150 (18%)

Query: 233 DGRSTEPPAPKAP-RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
           DG    P  P  P +P  P + G    K   G       GPPG +G P  P P   P  P
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGIPGS---KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 292 S-VQPSHQPLSKALESPLGL-------RPHLPLLMGGQAALKPE--------PGRPGEES 335
             +     P       P G         P  P L G + AL P+        PG PG   
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 336 ----PAPKQELHQPSFPTPQLSPLPMPGNP 361
               P PK ++     P  Q  P+  PG P
Sbjct: 791 LDGLPGPKGDVG----PNGQPGPMGPPGLP 816



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 72/250 (28%)

Query: 239 PPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSAT--PCGPSVQPS 296
           PP P       P   G+   K  +G       GPPG  G P  P       P GP + PS
Sbjct: 395 PPGP-------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS 447

Query: 297 HQ------------PLSKALESPLGLR---------------------PHLPLLMGGQAA 323
            +            P  K L+   G++                     P LP L G   +
Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 324 L-----KPEPGRPGEESPAPKQEL----HQPSFPTPQLSP---LPMPGNPADYNGLCVGP 371
           L     K E G+ G   P     +      P FP  +  P   L  PG   D  G    P
Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD-KGELGSP 566

Query: 372 ELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP--------VAAPHEEGLLLAPSSV- 422
               L       GQ+GL        P LP  K  P           P   GL   P ++ 
Sbjct: 567 GAPGLPGLPGTPGQDGL--------PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 423 PSGTPFQHPP 432
           P G P   PP
Sbjct: 619 PMGPPGFGPP 628


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 100/378 (26%), Positives = 124/378 (32%), Gaps = 54/378 (14%)

Query: 197  GDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKN 256
            G P P  +   +    LK     +    LP    E  G   EP  P  P P  P + G  
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 257  YPKAWQGASS-GEAAGPPGWQGCPDEPWPSAT--------PCGPSVQPSHQPLSKALESP 307
              K   G       +GP G+QG P +P             P GP   P   P    L  P
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPG-LPGQPGLIGP 1022

Query: 308  LGLR----------------PHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQ 351
             GL+                P  P  + GQ      PG+ G++       +  P  P P+
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 352  LSP-LP-MPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAA 409
              P LP  PGNP    G    P L  L       GQ GL     +P P  P+G   P   
Sbjct: 1083 GEPGLPGYPGNPG-IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP--- 1138

Query: 410  PHEEGLLLAPSSV-PSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGG 468
            P   GL   P  V   G P Q  P G       +  G+ G             AG    G
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD--GIPG------------PAGQK--G 1182

Query: 469  CPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEP 528
             P +  F   G   L  L     + G P  P +P  G P P   P     P +Q P   P
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 529  QTVARAC--PQSAKPPSG 544
             +   A   P+    P G
Sbjct: 1241 GSPGPALEGPKGNPGPQG 1258



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 42/132 (31%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 240 PAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQP 299
           P P  P P  P   G   PK  +G       GPPG  G    P P     GP+ QP   P
Sbjct: 756 PGPPGP-PGLPGFKGALGPKGDRGFPG--PPGPPGRTGLDGLPGPKGD-VGPNGQPG--P 809

Query: 300 LSKALESPLGLR--PHLPLLMG--GQAAL------KPEPGRPGEESPAPKQELHQPSFPT 349
           +       +G++  P  P + G  GQ  L      K +PG PG + P P  E   P  P 
Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 350 PQLSPLPMPGNP 361
               P+  PG+P
Sbjct: 870 AP-GPIGPPGSP 880



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 67/248 (27%), Positives = 88/248 (35%), Gaps = 38/248 (15%)

Query: 179  GSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTE 238
            G   +  +P     P + GD     ++S+          E  LP   P  +  + G   +
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYP-GNPGIKGSVGD 1102

Query: 239  PPAPKAP-------RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
            P  P  P       +P  P   G   P   +G S     GPPG  G P EP P      P
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-----GPPGNPGLPGEPGPVGGGGHP 1157

Query: 292  SVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFP--T 349
              QP   P  K      G+         G A  K EPG+PG  +P P      P  P  +
Sbjct: 1158 G-QPG-PPGEKGKPGQDGIP--------GPAGQKGEPGQPGFGNPGP------PGLPGLS 1201

Query: 350  PQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPML--PEGKLSPV 407
             Q     +PG P   N    GP+      F+ + G +G      SP P L  P+G   P 
Sbjct: 1202 GQKGDGGLPGIPG--NPGLPGPK--GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 408  AAPHEEGL 415
              P   GL
Sbjct: 1258 GPPGRPGL 1265



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 52/187 (27%), Positives = 62/187 (33%), Gaps = 33/187 (17%)

Query: 187  PAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPR 246
            P P   P R G P P                  E P  LP  +  + G    P  P  P 
Sbjct: 1254 PGPQGPPGRPGLPGP------------------EGPPGLP-GNGGIKGEKGNPGQPGLPG 1294

Query: 247  PKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQ-PSHQPLSKALE 305
               P + G   P   QG       G PG  G   +P     P  P ++ PS  P S   E
Sbjct: 1295 --LPGLKGDQGPPGLQGNP-----GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1347

Query: 306  SPLGL-----RPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGN 360
               GL      P LP   G    +K + G PG       + L  P  P     P   PG+
Sbjct: 1348 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1407

Query: 361  PADYNGL 367
            P   NGL
Sbjct: 1408 PG-RNGL 1413



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 28/150 (18%)

Query: 233 DGRSTEPPAPKAP-RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
           DG    P  P  P +P  P + G    K   G       GPPG +G P  P P   P  P
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGIPGS---KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 292 S-VQPSHQPLSKALESPLGL-------RPHLPLLMGGQAALKPE--------PGRPGEES 335
             +     P       P G         P  P L G + AL P+        PG PG   
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 336 ----PAPKQELHQPSFPTPQLSPLPMPGNP 361
               P PK ++     P  Q  P+  PG P
Sbjct: 791 LDGLPGPKGDVG----PNGQPGPMGPPGLP 816



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 72/250 (28%)

Query: 239 PPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSAT--PCGPSVQPS 296
           PP P       P   G+   K  +G       GPPG  G P  P       P GP + PS
Sbjct: 395 PPGP-------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS 447

Query: 297 HQ------------PLSKALESPLGLR---------------------PHLPLLMGGQAA 323
            +            P  K L+   G++                     P LP L G   +
Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 324 L-----KPEPGRPGEESPAPKQEL----HQPSFPTPQLSP---LPMPGNPADYNGLCVGP 371
           L     K E G+ G   P     +      P FP  +  P   L  PG   D  G    P
Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD-KGELGSP 566

Query: 372 ELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP--------VAAPHEEGLLLAPSSV- 422
               L       GQ+GL        P LP  K  P           P   GL   P ++ 
Sbjct: 567 GAPGLPGLPGTPGQDGL--------PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 423 PSGTPFQHPP 432
           P G P   PP
Sbjct: 619 PMGPPGFGPP 628


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 100/378 (26%), Positives = 124/378 (32%), Gaps = 54/378 (14%)

Query: 197  GDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKN 256
            G P P  +   +    LK     +    LP    E  G   EP  P  P P  P + G  
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 257  YPKAWQGASS-GEAAGPPGWQGCPDEPWPSAT--------PCGPSVQPSHQPLSKALESP 307
              K   G       +GP G+QG P +P             P GP   P   P    L  P
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPG-LPGQPGLIGP 1022

Query: 308  LGLR----------------PHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQ 351
             GL+                P  P  + GQ      PG+ G++       +  P  P P+
Sbjct: 1023 PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082

Query: 352  LSP-LP-MPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAA 409
              P LP  PGNP    G    P L  L       GQ GL     +P P  P+G   P   
Sbjct: 1083 GEPGLPGYPGNPG-IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP--- 1138

Query: 410  PHEEGLLLAPSSV-PSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGG 468
            P   GL   P  V   G P Q  P G       +  G+ G             AG    G
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD--GIPG------------PAGQK--G 1182

Query: 469  CPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEP 528
             P +  F   G   L  L     + G P  P +P  G P P   P     P +Q P   P
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 529  QTVARAC--PQSAKPPSG 544
             +   A   P+    P G
Sbjct: 1241 GSPGPALEGPKGNPGPQG 1258



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 42/132 (31%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 240 PAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQP 299
           P P  P P  P   G   PK  +G       GPPG  G    P P     GP+ QP   P
Sbjct: 756 PGPPGP-PGLPGFKGALGPKGDRGFPG--PPGPPGRTGLDGLPGPKGD-VGPNGQPG--P 809

Query: 300 LSKALESPLGLR--PHLPLLMG--GQAAL------KPEPGRPGEESPAPKQELHQPSFPT 349
           +       +G++  P  P + G  GQ  L      K +PG PG + P P  E   P  P 
Sbjct: 810 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 350 PQLSPLPMPGNP 361
               P+  PG+P
Sbjct: 870 AP-GPIGPPGSP 880



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 70/260 (26%), Positives = 91/260 (35%), Gaps = 40/260 (15%)

Query: 179  GSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTE 238
            G   +  +P     P + GD     ++S+          E  LP   P  +  + G   +
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYP-GNPGIKGSVGD 1102

Query: 239  PPAPKAP-------RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
            P  P  P       +P  P   G   P   +G S     GPPG  G P EP P      P
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-----GPPGNPGLPGEPGPVGGGGHP 1157

Query: 292  SVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFP--T 349
              QP   P  K      G+         G A  K EPG+PG  +P P      P  P  +
Sbjct: 1158 G-QPG-PPGEKGKPGQDGIP--------GPAGQKGEPGQPGFGNPGP------PGLPGLS 1201

Query: 350  PQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPML--PEGKLSPV 407
             Q     +PG P   N    GP+      F+ + G +G      SP P L  P+G   P 
Sbjct: 1202 GQKGDGGLPGIPG--NPGLPGPK--GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 408  AAPHEEGLLLAPSSVPSGTP 427
              P   G    P   P G P
Sbjct: 1258 GPPGRPGFQGLPG--PEGPP 1275



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 57/190 (30%), Positives = 70/190 (36%), Gaps = 21/190 (11%)

Query: 184  SPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPK 243
            SP PA  EGP+  G+P P+         F  L    E P  LP  +  + G    P  P 
Sbjct: 1242 SPGPAL-EGPK--GNPGPQ--GPPGRPGFQGLPGP-EGPPGLP-GNGGIKGEKGNPGQPG 1294

Query: 244  APRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQ-PSHQPLSK 302
             P    P + G   P   QG       G PG  G   +P     P  P ++ PS  P S 
Sbjct: 1295 LPG--LPGLKGDQGPPGLQGNP-----GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1347

Query: 303  ALESPLGL-----RPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPM 357
              E   GL      P LP   G    +K + G PG       + L  P  P     P   
Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1407

Query: 358  PGNPADYNGL 367
            PG+P   NGL
Sbjct: 1408 PGDPG-RNGL 1416



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 28/150 (18%)

Query: 233 DGRSTEPPAPKAP-RPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGP 291
           DG    P  P  P +P  P + G    K   G       GPPG +G P  P P   P  P
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGIPGS---KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 292 S-VQPSHQPLSKALESPLGL-------RPHLPLLMGGQAALKPE--------PGRPGEES 335
             +     P       P G         P  P L G + AL P+        PG PG   
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTG 790

Query: 336 ----PAPKQELHQPSFPTPQLSPLPMPGNP 361
               P PK ++     P  Q  P+  PG P
Sbjct: 791 LDGLPGPKGDVG----PNGQPGPMGPPGLP 816



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 72/250 (28%)

Query: 239 PPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSAT--PCGPSVQPS 296
           PP P       P   G+   K  +G       GPPG  G P  P       P GP + PS
Sbjct: 395 PPGP-------PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS 447

Query: 297 HQ------------PLSKALESPLGLR---------------------PHLPLLMGGQAA 323
            +            P  K L+   G++                     P LP L G   +
Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 324 L-----KPEPGRPGEESPAPKQEL----HQPSFPTPQLSP---LPMPGNPADYNGLCVGP 371
           L     K E G+ G   P     +      P FP  +  P   L  PG   D  G    P
Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD-KGELGSP 566

Query: 372 ELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP--------VAAPHEEGLLLAPSSV- 422
               L       GQ+GL        P LP  K  P           P   GL   P ++ 
Sbjct: 567 GAPGLPGLPGTPGQDGL--------PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 423 PSGTPFQHPP 432
           P G P   PP
Sbjct: 619 PMGPPGFGPP 628


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/297 (26%), Positives = 106/297 (35%), Gaps = 42/297 (14%)

Query: 85  SADEADELPPDLPKP-PSPAPSSEDPGL---------AQPRKRRLASLNAEA-LNNLLLE 133
           S D A E PP  P P P PAP + D  L         A P+K    S N +A L   LL+
Sbjct: 426 SGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLK 485

Query: 134 ------REDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEP 187
                 R+  S+       R     + R R+R        K+R R        +      
Sbjct: 486 SLRSRLRDGPSAPLEAPEPRKPVTAQERQRER------EEKRRRRQERAKEREKRRQERE 539

Query: 188 APDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP---PAPKA 244
             + G    G P+   LA L  +   +   ER   +  P A A     +  P   P P  
Sbjct: 540 RKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTP 599

Query: 245 PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKAL 304
            +P  P       P   Q  S+G  +GP         P P+  P GP+  P+  P    +
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGP--------VPQPACPPPGPAPHPTGPPGPIPV 651

Query: 305 ESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNP 361
            +P  +     LL     +L P PG PG  +P        P FP P L P    G P
Sbjct: 652 PAPPQIATSTSLL--AAQSLVPPPGLPGSSTPGV-----LPYFP-PGLPPPDAGGAP 700



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 11/123 (8%)

Query: 468 GCP---YKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTP 524
           GCP      P+A  G  ++   E P P       PA   +   +   PP +EP P  +  
Sbjct: 413 GCPDVEMPSPWAPSGDCAM---ESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG 469

Query: 525 TSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRR 584
                T A      A      +S LR G S      +   R+P   ++ + +R   RRRR
Sbjct: 470 AISDNTKAAL---KAALLKSLRSRLRDGPSA--PLEAPEPRKPVTAQERQREREEKRRRR 524

Query: 585 RRR 587
           + R
Sbjct: 525 QER 527


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/297 (26%), Positives = 106/297 (35%), Gaps = 42/297 (14%)

Query: 85  SADEADELPPDLPKP-PSPAPSSEDPGL---------AQPRKRRLASLNAEA-LNNLLLE 133
           S D A E PP  P P P PAP + D  L         A P+K    S N +A L   LL+
Sbjct: 426 SGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLK 485

Query: 134 ------REDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEP 187
                 R+  S+       R     + R R+R        K+R R        +      
Sbjct: 486 SLRSRLRDGPSAPLEAPEPRKPVTAQERQRER------EEKRRRRQERAKEREKRRQERE 539

Query: 188 APDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP---PAPKA 244
             + G    G P+   LA L  +   +   ER   +  P A A     +  P   P P  
Sbjct: 540 RKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTP 599

Query: 245 PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKAL 304
            +P  P       P   Q  S+G  +GP         P P+  P GP+  P+  P    +
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGP--------VPQPACPPPGPAPHPTGPPGPIPV 651

Query: 305 ESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNP 361
            +P  +     LL     +L P PG PG  +P        P FP P L P    G P
Sbjct: 652 PAPPQIATSTSLL--AAQSLVPPPGLPGSSTPGV-----LPYFP-PGLPPPDAGGAP 700



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 11/123 (8%)

Query: 468 GCP---YKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTP 524
           GCP      P+A  G  ++   E P P       PA   +   +   PP +EP P  +  
Sbjct: 413 GCPDVEMPSPWAPSGDCAM---ESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG 469

Query: 525 TSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRR 584
                T A      A      +S LR G S      +   R+P   ++ + +R   RRRR
Sbjct: 470 AISDNTKAAL---KAALLKSLRSRLRDGPSA--PLEAPEPRKPVTAQERQREREEKRRRR 524

Query: 585 RRR 587
           + R
Sbjct: 525 QER 527


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/297 (26%), Positives = 106/297 (35%), Gaps = 42/297 (14%)

Query: 85  SADEADELPPDLPKP-PSPAPSSEDPGL---------AQPRKRRLASLNAEA-LNNLLLE 133
           S D A E PP  P P P PAP + D  L         A P+K    S N +A L   LL+
Sbjct: 426 SGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLK 485

Query: 134 ------REDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEP 187
                 R+  S+       R     + R R+R        K+R R        +      
Sbjct: 486 SLRSRLRDGPSAPLEAPEPRKPVTAQERQRER------EEKRRRRQERAKEREKRRQERE 539

Query: 188 APDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP---PAPKA 244
             + G    G P+   LA L  +   +   ER   +  P A A     +  P   P P  
Sbjct: 540 RKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTP 599

Query: 245 PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKAL 304
            +P  P       P   Q  S+G  +GP         P P+  P GP+  P+  P    +
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGP--------VPQPACPPPGPAPHPTGPPGPIPV 651

Query: 305 ESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNP 361
            +P  +     LL     +L P PG PG  +P        P FP P L P    G P
Sbjct: 652 PAPPQIATSTSLL--AAQSLVPPPGLPGSSTPGV-----LPYFP-PGLPPPDAGGAP 700



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 11/123 (8%)

Query: 468 GCP---YKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTP 524
           GCP      P+A  G  ++   E P P       PA   +   +   PP +EP P  +  
Sbjct: 413 GCPDVEMPSPWAPSGDCAM---ESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG 469

Query: 525 TSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRR 584
                T A      A      +S LR G S      +   R+P   ++ + +R   RRRR
Sbjct: 470 AISDNTKAAL---KAALLKSLRSRLRDGPSA--PLEAPEPRKPVTAQERQREREEKRRRR 524

Query: 585 RRR 587
           + R
Sbjct: 525 QER 527


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/297 (26%), Positives = 106/297 (35%), Gaps = 42/297 (14%)

Query: 85  SADEADELPPDLPKP-PSPAPSSEDPGL---------AQPRKRRLASLNAEA-LNNLLLE 133
           S D A E PP  P P P PAP + D  L         A P+K    S N +A L   LL+
Sbjct: 287 SGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLK 346

Query: 134 ------REDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEP 187
                 R+  S+       R     + R R+R        K+R R        +      
Sbjct: 347 SLRSRLRDGPSAPLEAPEPRKPVTAQERQRER------EEKRRRRQERAKEREKRRQERE 400

Query: 188 APDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP---PAPKA 244
             + G    G P+   LA L  +   +   ER   +  P A A     +  P   P P  
Sbjct: 401 RKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTP 460

Query: 245 PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKAL 304
            +P  P       P   Q  S+G  +GP         P P+  P GP+  P+  P    +
Sbjct: 461 VQPTSPPPGPVAQPTGPQPQSAGSTSGP--------VPQPACPPPGPAPHPTGPPGPIPV 512

Query: 305 ESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNP 361
            +P  +     LL     +L P PG PG  +P        P FP P L P    G P
Sbjct: 513 PAPPQIATSTSLL--AAQSLVPPPGLPGSSTPGV-----LPYFP-PGLPPPDAGGAP 561



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 11/123 (8%)

Query: 468 GCP---YKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTP 524
           GCP      P+A  G  ++   E P P       PA   +   +   PP +EP P  +  
Sbjct: 274 GCPDVEMPSPWAPSGDCAM---ESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG 330

Query: 525 TSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRR 584
                T A      A      +S LR G S      +   R+P   ++ + +R   RRRR
Sbjct: 331 AISDNTKAAL---KAALLKSLRSRLRDGPSA--PLEAPEPRKPVTAQERQREREEKRRRR 385

Query: 585 RRR 587
           + R
Sbjct: 386 QER 388


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 94/430 (21%), Positives = 130/430 (30%), Gaps = 68/430 (15%)

Query: 42   PESPGHLTGRRKNYPLRKRPLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPS 101
            P +P   TG     P+      P+ P A    L     +  P++        P    PP 
Sbjct: 605  PATPAAATGEAA--PVLTVQPAPQAPPAVSTPLPL--GLQQPQAQQPPQAPTPQAAAPPQ 660

Query: 102  PAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSR----AGDPHRS--- 154
                   PGLA   ++ +      A    +L ++         RS+    A  PH S   
Sbjct: 661  ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA 720

Query: 155  ----------RDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPD-------EGPRRDG 197
                      +D   AT     +   P+  D        SP PAP        +GP    
Sbjct: 721  SVIVSAPPPAQDPAPATPVAKGAGLGPQAPD-----SQASPAPAPQIPAAAPLKGPGPSS 775

Query: 198  DPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNY 257
             P+    A L  +  L        P R P     V    +EPP    P P+ P      +
Sbjct: 776  SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835

Query: 258  PKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPL-----------SKALES 306
                    +     PP     P  P P   P  P  QP   PL           S A+ S
Sbjct: 836  V-----IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890

Query: 307  PLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELH---QPSFPTP------QLSPLPM 357
                   LP        L+  P +   +SP P   LH   +P+ P P      Q+   P 
Sbjct: 891  SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950

Query: 358  PGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLL 417
            P  P         P+        +  G       G +P        L P+ +P     +L
Sbjct: 951  PALPQ--------PKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP--AASVL 1000

Query: 418  APSSVPSGTP 427
                 PSGTP
Sbjct: 1001 VSGQAPSGTP 1010



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 68/239 (28%), Positives = 82/239 (34%), Gaps = 47/239 (19%)

Query: 215 LSQER-ELPLRLPRAHAEVDGRS--TEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAG 271
           L QER + PL     H  V      + PP  + P P  P   G     A  G  + ++  
Sbjct: 700 LPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG-----AGLGPQAPDSQA 754

Query: 272 PPGWQGCPDEPWPSATPC---GPSVQPS--HQPLSKALESPLGLRPHLPLLMGGQAALKP 326
            P     P    P+A P    GPS  PS  HQ       +PLG  PHLP          P
Sbjct: 755 SPA----PAPQIPAAAPLKGPGPSSSPSLPHQ-------APLGDSPHLP---------SP 794

Query: 327 EPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCV------------GPELT 374
            P RP    P+  Q + +P    P L P P P  P    G+ V             P  T
Sbjct: 795 HPTRPPSRPPSRPQSVSRPP-SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853

Query: 375 ALGSFYLYCGQEGLQCGG-YSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPP 432
           A G        +     G   P P LP    S   A   E     P+  PS    Q PP
Sbjct: 854 APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP 912


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 131/561 (23%), Positives = 187/561 (33%), Gaps = 106/561 (18%)

Query: 68  KACKVLLTRLENVAGPRSADEADEL----------PPDLPKPPSPAPSSEDPGLAQPRKR 117
           K C + LT L   A    +  +  L          P  LP+ P P+      GL +    
Sbjct: 98  KLCPLSLTSLPREAAVNFSYRSQTLLQEAQVLQGSPELLPRSPKPS------GLQRLAPE 151

Query: 118 RLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLG 177
              +L    L +L L  +D  + A  R    G P  S    ++T   SS + RPR+    
Sbjct: 152 EATALPLRRLCHLSLMEKDLGTTAHPR----GFPELSH---KSTAAASSRQSRPRVR--- 201

Query: 178 GGSRDLSPEPAPDEGPRRDGDPAPKRLASL-----NAAAFLKLSQERE-----------L 221
             S  L P      G +      PKRL+ L      AA   +    R            L
Sbjct: 202 --SASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTL 259

Query: 222 PLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASS----------GEAAG 271
           P       + +  R +  P P+    +      +   + W+              G    
Sbjct: 260 PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPL 319

Query: 272 PPGWQ------GCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALK 325
           PPG        G P +P P  TP  P   P+                H P+L  G +   
Sbjct: 320 PPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQ-------------HQPILTPGHSQPI 366

Query: 326 PEPGRP--GEESPAPKQELHQPSFPTP--QLSPLP--MPGNPADYNGLCVGPELTALGSF 379
           P PG+P   +  P P + L     PTP   L+P P  MPG P     L + P L  L   
Sbjct: 367 PTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRP-----LRLPPPLRLLRPG 421

Query: 380 YLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYC 439
                Q     G   P P+LP G+      P +    L P   P       PP   SR  
Sbjct: 422 QPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQP---LPPG--PDARSISDPPAPRSRLP 476

Query: 440 SSEDTGVNGYSICGVLPLSVTHAG-TTCGGCPYKMPFAAEGCRSLGQLE----FPLPEAG 494
                G+      G  P +   A  TT  G P      AE   ++G  +    F + E  
Sbjct: 477 IRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIA 536

Query: 495 HPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVA--------RACPQSAKPP--SG 544
              SP+         S  P+      L+ P+ +P+ ++        R+  + AK P  SG
Sbjct: 537 AAESPSATY--SATFSCKPSGAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSG 594

Query: 545 SKSGLRTGSSCRHTARSKAAR 565
            +S  R  +    T  S+  R
Sbjct: 595 PRSAQRRNAVSSSTNNSRTKR 615


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 130/550 (23%), Positives = 170/550 (30%), Gaps = 93/550 (16%)

Query: 35  EGVEPGMPESPGHLTGRRKNYPLRKRPLVPEKPKACKVLLTRLENVAGPRSADEADELPP 94
           +   PG   SPG  +G  +  PL ++ L   +  A + +       A  RSA  A     
Sbjct: 98  KNTSPGPVSSPGRASGTTRPGPLGQKGL---RISAEETVARGKATEAPKRSALSAG---- 150

Query: 95  DLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRS 154
              +  +  P+   P  A  R+ R A      L              G R+S +     S
Sbjct: 151 --ARRDTSGPTPGTPSPAMARRSRAAGTEV-GLPRPAPSARPRPPTEGPRKSVS-----S 202

Query: 155 RDRDRATGGWSSSKKRPRLGDLGG----GSRDLSPEPAPDEGPRRDG------------- 197
                 T    ++++RP  G  GG     SR LS    P   P R G             
Sbjct: 203 ASEHSTTEPSPAARRRPSAG--GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260

Query: 198 -DPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKN 256
             P PK L +L         ++    L    +        + PP+P AP    P +    
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP----PSLQTLP 316

Query: 257 YPKAWQGASSGEAAGPPGWQG----CPDEPW-PSATPCGPSVQPSHQPLSKALESPLGLR 311
            P A   + +  + G P  Q      P  P  P ATP      P   P + AL  PL   
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP------PPQAPPALAL-PPLQAP 369

Query: 312 PHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGP 371
           P  P          P P  P   +    Q    P    P  +P   P +P       V P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP------VSP 423

Query: 372 ELTALGSFYLYCGQEGLQCGGYSPC--PMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQ 429
             T             LQ     P   PM P     P A P     L AP    +  P Q
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP----LAAPPLQLAKPPPQ 479

Query: 430 HPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFP 489
            PP                       PL    +       P + PF+      +  L  P
Sbjct: 480 APP------------------ALATPPLQALPSPP--ASFPGQAPFSPSASLPMSPLATP 519

Query: 490 LPEAGHPASPAHPLLGCPVPSVP-------PAAEPVPHLQTPTSEPQTVARACPQSAKPP 542
            P+A  P   A PLL  P PS P       P   P P   T  S P+      P    PP
Sbjct: 520 PPQA--PPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576

Query: 543 SGSKSGLRTG 552
           S S S   +G
Sbjct: 577 SRSPSSTLSG 586



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 59/199 (29%), Positives = 74/199 (37%), Gaps = 26/199 (13%)

Query: 397 PMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVL- 455
           P    G+ +P A     G + +P    SGT    P        S+E+T   G +      
Sbjct: 86  PASGRGERAPPAKNTSPGPVSSPGRA-SGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144

Query: 456 -PLSVTHAGTTCGGCP-YKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPP 513
             LS      T G  P    P  A   R+ G  E  LP     A P  P  G P  SV  
Sbjct: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPPTEG-PRKSVSS 202

Query: 514 AAEPVPHLQTPTSEPQTVARACPQSA----KPPSGSKSG--------LRTGSSCRHTARS 561
           A+E        T+EP   AR  P +     +P S S S          R+G S R T R+
Sbjct: 203 ASEH------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256

Query: 562 KAARRPSHPKQPRVQRPRP 580
            A   PS PK   +Q  RP
Sbjct: 257 PA--HPSQPKPKGLQALRP 273


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 133/577 (23%), Positives = 173/577 (29%), Gaps = 117/577 (20%)

Query: 35  EGVEPGMPESPGHLTGRRKNYPLRKRPL------------VPEKPKACKVLLTRLENVAG 82
           +   PG   SPG  +G  +  PL ++ L              E PK   +      + +G
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166

Query: 83  P-----------RSADEADEL------PPDLPKPPSPAP-----------SSEDPGLAQP 114
           P           RS     E+      P   P+PP+  P           ++E    A+ 
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 115 RKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDP----HRSRDRDRATGGWSSSKKR 170
           R      L   A  +L       SS A +  S  G P    H S+ + +        +  
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286

Query: 171 PRLGDLGGGSRDLSPEPAPDEGPRRD-GDPAPKRLASLNAAAFLKLSQERELPLRLPRAH 229
           P   D       LS  P     P       AP  L +   ++ L       LPL      
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL------ 340

Query: 230 AEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQG----CPDEPW-P 284
                    PP+P AP    P +     P A   + +  + G P  Q      P  P  P
Sbjct: 341 --------APPSPSAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 388

Query: 285 SATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQ 344
            ATP      P   P + AL  PL   P  P          P P  P   +    Q    
Sbjct: 389 LATP------PPQAPPALAL-PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441

Query: 345 PSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPC--PMLPEG 402
           P    P  +P   P +P       V P  T             LQ     P   PM P  
Sbjct: 442 PPPSPPVQAPFSPPASPP------VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 403 KLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHA 462
              P A P     L AP    +  P Q PP                       PL    +
Sbjct: 496 TPPPQAPPP----LAAPPLQLAKPPPQAPP------------------ALATPPLQALPS 533

Query: 463 GTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVP-------PAA 515
                  P + PF+      +  L  P P+A  P   A PLL  P PS P       P  
Sbjct: 534 PP--ASFPGQAPFSPSASLPMSPLATPPPQA--PPVLAAPLLQVP-PSPPASPTLQAPRR 588

Query: 516 EPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTG 552
            P P   T  S P+      P    PPS S S   +G
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 97/396 (24%), Positives = 125/396 (31%), Gaps = 85/396 (21%)

Query: 223 LRLPRAHAEVDGRSTEPPAPKA-PRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDE 281
           L LP   A     ++ P +P A P P+ P     +  +A           PP     P  
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA----PFSPPPSPP--VQAPFS 453

Query: 282 PWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQ- 340
           P P++ P  PS  P  Q        PL + P  P       +  P P  P   +  P Q 
Sbjct: 454 P-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 341 ----ELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPC 396
                   P+  TP L  LP P  PA + G                          +SP 
Sbjct: 513 AKPPPQAPPALATPPLQALPSP--PASFPGQ-----------------------APFSPS 547

Query: 397 PMLPEGKLSPVAAPHEEG-------LLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGY 449
             LP   +SP+A P  +        LL  P S P+    Q P    +      DT V+G 
Sbjct: 548 ASLP---MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT---PGPDTSVSGP 601

Query: 450 SICGVL----------PLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASP 499
            +   L            S T +G    G         E  R         PE G  ASP
Sbjct: 602 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASP 657

Query: 500 --------AHPLLGCPVPSVPPA---AEPVPHLQTPTSEPQTVARAC-------PQSAKP 541
                    HP      P+ P A   A   P    P + P +    C       P+SA P
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717

Query: 542 -PSGSKSGLRTGSSCRHTARSKAARRPSH-PKQPRV 575
            P     G   G+S    A    A   S  PKQ R+
Sbjct: 718 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 106/500 (21%), Positives = 156/500 (31%), Gaps = 87/500 (17%)

Query: 93  PPDLPKPPSPAPSS--EDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGD 150
           PP  P+PP P   +     G A    R+  +  A  +    +   +++  AG  RS    
Sbjct: 29  PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP--ESAPRAGPTRSAGTS 86

Query: 151 PHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAA 210
                 R  A+G           G+    +++ SP P    G R  G   P  L      
Sbjct: 87  SRNPASRPPASGR----------GERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLR 135

Query: 211 AFLKLSQERELPLRLPRAHAEVDG--RSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGE 268
              + +  R      P+  A   G  R T  P P  P P   +          +  ++G 
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR----------RSRAAGT 185

Query: 269 AAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEP 328
             G P        P PSA P  P+  P     S +  S                    EP
Sbjct: 186 EVGLP-------RPAPSARPRPPTEGPRKSVSSASEHSTT------------------EP 220

Query: 329 GRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVG-PELTALGSFYLYCGQEG 387
                  P+    L +P+  +   S  P+  +PA       G P   A  S     G + 
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPL-SSPARSGPSARGTPRAPAHPSQPKPKGLQA 279

Query: 388 LQCGGYSP-----CPMLPEGKLSPVAAPHEEGLLL--APSSVPSGTPFQHPPWGSSRYCS 440
           L+    +P      P L     SP+A P     L   AP ++P+       P  SS  C 
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA------TPHSSSLTCQ 333

Query: 441 SEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPA 500
                     +   LPL+               P A    ++   L  P  +A H   P+
Sbjct: 334 ----------LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383

Query: 501 HPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKP--PSGSKSGLRTGSSCRHT 558
            PL         P A P P      + P   A   P ++ P  P  + S     +   H 
Sbjct: 384 PPL--------SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435

Query: 559 ARSKAARRPSHPKQPRVQRP 578
            ++  +  PS P Q     P
Sbjct: 436 LQAPFSPPPSPPVQAPFSPP 455


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 128/557 (22%), Positives = 179/557 (32%), Gaps = 115/557 (20%)

Query: 94  PDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHR 153
           PD   PP   P+ ED   A  ++R+ +S       +L +ER         RR R  +  R
Sbjct: 430 PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEI----SLAVER--------ARRRREEEERR 477

Query: 154 SRDRDRATGGWSSSKKRPRLGD-LGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAF 212
            ++  RA    + ++K  RL +  G   + L  EPA    P     PAP           
Sbjct: 478 MQEERRA----ACAEKLKRLDEKFGAPDKRLKAEPAAP--PAAPSTPAPPP--------- 522

Query: 213 LKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGP 272
             + +E   P   P A A       E PA   P    P       P    G  S  +   
Sbjct: 523 -AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSS 581

Query: 273 PGWQGCPDEPW---------------------PSATPCGPSVQPSHQPLSKALESPLGLR 311
             ++  P EP                      P   P G  + P+ QP S+ L  P    
Sbjct: 582 GSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP---- 637

Query: 312 PHLPLLMGGQAALKPEPGRPGEESPAPKQELHQ-PSFPTPQLSPLPMPGNPAD--YNGLC 368
                    Q +L P   R  +E    +Q+ HQ          P P+P +P      G  
Sbjct: 638 -------KYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAV 690

Query: 369 VGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP---VAAPHEEGLLL-------- 417
             P+        LY G  G         P +P     P   +  P+ +  LL        
Sbjct: 691 PAPQAPPPPPKALYPGALGRP-------PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDF 743

Query: 418 -APSSVPSG-TPFQHPPWGSSRYCSSEDTGVNGYSIC---GVLPLSVTHA-------GTT 465
             P   PSG  P +    G S   SSE    +  ++    G  P+    A        T 
Sbjct: 744 YPPGVHPSGLVPRERSDSGGS---SSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800

Query: 466 CGGCPYKMPF---AAEGCRSLGQLEFPLPE-----AGHPASPAHPLLGCPVPSVPPAAEP 517
               P   P    A E  + +     P+P      A +P  P +   G P+ S  P  EP
Sbjct: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPI-SRFPLEEP 859

Query: 518 VPH-LQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQ 576
            P  L  P    +      P   K P   ++   TG         +A R+P+       Q
Sbjct: 860 GPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG--------PEAGRKPARGVGSGGQ 911

Query: 577 RPRPRRRRRRRTNGWVP 593
            P P RR  R    W P
Sbjct: 912 GPPPPRRESRTETRWGP 928



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 72/296 (24%), Positives = 100/296 (33%), Gaps = 52/296 (17%)

Query: 90   DELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAG 149
            +E PP LP PP P  SS    L Q      A +  +AL  L   +   ++  G  R + G
Sbjct: 1444 EERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQ-QALAQLSSRQGSVTAPGGHPRHKPG 1502

Query: 150  DPHRSR----------DRDRATGGWSS----SKKRPRLGDLGGGSRD---LSPEPAPDEG 192
             P   +          +  R   G SS     +  P +  +GG  RD   +SP P     
Sbjct: 1503 LPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFP----- 1557

Query: 193  PRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKV 252
            P+R   P  K           +L QE  LP   P   +   G   E P P+A      + 
Sbjct: 1558 PKRRERPPRKP----------ELLQEESLP---PPHSSGFLGSKPEGPGPQAE----SRD 1600

Query: 253  NGKN--YPKAWQGASSGEAAGPPGWQGCPDEPW-----PSATPCGPSVQPSHQPLSKALE 305
             G     P  W    +  A     ++    EPW     P     G  +  S   +  + +
Sbjct: 1601 TGTEALTPHIWNRLHT--ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGD 1658

Query: 306  SPLGLRPHLPLLM---GGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMP 358
            S +   P         G + A +  P RPG  SP        P    P   P P P
Sbjct: 1659 SQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAP 1714



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 58/280 (20%), Positives = 92/280 (32%), Gaps = 48/280 (17%)

Query: 52  RKNYPLRKRPLVPEKPKACKVLLTRLENVAG----------------PRSADEADELPPD 95
           R+     +R +  E+  AC   L RL+   G                P +      +P +
Sbjct: 468 RRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKE 527

Query: 96  LPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSR 155
           LP PP+P P+S      +P +   A            +   T  +A      +G    S 
Sbjct: 528 LPAPPAPPPASAPTPETEPEEPAQAP---------PAQSTPTPGVAAAPTLVSGGGSTS- 577

Query: 156 DRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKL 215
               ++G + +S   P+L    G      PEP P+E P     P PK          ++ 
Sbjct: 578 --STSSGSFEASPVEPQLPSKEG------PEP-PEEVPPPTTPPVPK----------VEP 618

Query: 216 SQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGW 275
             +   P R P +      +  +   P+  R +  ++  +     WQ    G A   P  
Sbjct: 619 KGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTP-- 676

Query: 276 QGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLP 315
              P  P P      P+ Q    P        LG  P +P
Sbjct: 677 -VPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMP 715



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 512 PPAAEPVPHLQTPTSEPQTVARACPQSAK-PPSGSKSGLRTGSSCRHTARSKAARRPS 568
           PP ++P+P  QTP S       A P++    PSG KS  +  +S  H A     R  S
Sbjct: 105 PPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQ--ASVTHGAHGDGGRASS 160


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 89/352 (25%), Positives = 106/352 (30%), Gaps = 54/352 (15%)

Query: 233 DGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGC-PDEPWPSATPCGP 291
           D    E P+  A  P+ P   G N P+       G+  GPP   G  P  P P   P GP
Sbjct: 22  DVSQEESPSLIAGNPQGPSPQGGNKPQG-PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 80

Query: 292 SVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQ 351
              P     S++  SP G +P  P   GG     P P  PG+    P Q  ++P  P P 
Sbjct: 81  ---PPQGDKSRSPRSPPG-KPQGPPPQGGNQPQGPPP-PPGKPQGPPPQGGNRPQGPPPP 135

Query: 352 LSPLPMP------GNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLS 405
             P   P       +P    G   GP             Q G Q  G  P P  P+G   
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPP-----------PQGGNQPQGPPPPPGKPQG--- 181

Query: 406 PVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTT 465
               P  +G        P G P   PP G     S    G          P      G  
Sbjct: 182 ----PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG---------KPQGPPPQGGN 228

Query: 466 CGGCPYKMPFAAEGCRSLG--QLEFPLPEA---GHPASPAHPLLGCPVPSVPPAAEPVPH 520
               P   P   +G    G  + + P P     G PA           P   P   P   
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288

Query: 521 LQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQ 572
              P   P        Q   PP+G   G           R     RPS P Q
Sbjct: 289 GNNPQGPPPPAGGNPQQPQAPPAGQPQG---------PPRPPQGGRPSRPPQ 331



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 81/325 (24%), Positives = 105/325 (32%), Gaps = 59/325 (18%)

Query: 226 PRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEP-WP 284
           P+  +   G   + P P   +P+ P   G N P+       G+  GPP        P  P
Sbjct: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQG--PPPPGKPQGPPPQGDKSRSPRSP 93

Query: 285 SATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRP------GEESPAP 338
              P GP  Q  +QP  +    P G     P   G +    P PG+P      G++S +P
Sbjct: 94  PGKPQGPPPQGGNQP--QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151

Query: 339 KQELHQPSFPTPQ-----LSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGY 393
           +    +P  P PQ       P P PG P        GP                   GG 
Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-------GPP----------------PQGGK 188

Query: 394 SPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCS--------SEDTG 445
            P    P GK      P  +G     S  P G P   PP G ++                
Sbjct: 189 KPQGPPPPGK---PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245

Query: 446 VNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLG 505
             G    G  P          GG   +   +  G +  G    P  E  +P  P  P  G
Sbjct: 246 QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG-KPQGP---PQQEGNNPQGPPPPAGG 301

Query: 506 CP-VPSVPPAAEPVPHLQTPTSEPQ 529
            P  P  PPA +P    Q P   PQ
Sbjct: 302 NPQQPQAPPAGQP----QGPPRPPQ 322



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 80/327 (24%), Positives = 110/327 (33%), Gaps = 65/327 (19%)

Query: 119 LASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGG 178
           LA  +A+ LN  + + E  S +AG  +  +      +  ++  G      K       GG
Sbjct: 11  LALSSAQNLNEDVSQEESPSLIAGNPQGPS-----PQGGNKPQGPPPPPGKPQGPPPQGG 65

Query: 179 GSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTE 238
                 P P   +GP   GD                 S+    P   P+      G   +
Sbjct: 66  NKPQGPPPPGKPQGPPPQGDK----------------SRSPRSPPGKPQGPPPQGGNQPQ 109

Query: 239 PPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEP-WPSATPCGPSVQPSH 297
            P P   +P+ P   G N P+       G+  GPP        P  P   P GP  Q  +
Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQG--PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 167

Query: 298 QPLSKALESPLGLRPHLPLLMGGQAAL-KPEPGRP------GEESPAPKQELHQPSFPTP 350
           QP  +    P G +P  P   GG+     P PG+P      G++S + +    +P  P P
Sbjct: 168 QP--QGPPPPPG-KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP 224

Query: 351 Q-----LSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLS 405
           Q       P P PG P        GP                   GG  P    P GK  
Sbjct: 225 QGGNQPQGPPPPPGKPQ-------GPP----------------PQGGNKPQGPPPPGK-- 259

Query: 406 PVAAPHEEGLLLAPSSVPSGTPFQHPP 432
           P   P + G     +  P G P Q PP
Sbjct: 260 PQGPPAQGGSKSQSARSPPGKP-QGPP 285



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 41/166 (24%), Positives = 55/166 (33%), Gaps = 23/166 (13%)

Query: 177 GGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRS 236
           GG      P P   +GP   GD                 S+  + P   P+      G  
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDK----------------SRSSQSPPGKPQGPPPQGGNQ 229

Query: 237 TEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEP--WPSATPCGPSVQ 294
            + P P   +P+ P   G N P+       G+  GPP   G   +    P   P GP  Q
Sbjct: 230 PQGPPPPPGKPQGPPPQGGNKPQG--PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ 287

Query: 295 PSHQPLSKALESPLGLRPHLPLL-MGGQAALKPEPGRPGEESPAPK 339
             + P  +    P G  P  P     GQ    P P + G  S  P+
Sbjct: 288 EGNNP--QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 59/227 (25%), Positives = 79/227 (34%), Gaps = 30/227 (13%)

Query: 148 AGDPHRSRDRDRATGGWSSSKKRPRLGDLG--------GGSRDLSPEPAPDEGPRRDGDP 199
           +G P    D  RA+       +RP L DL         G     S  P P  G R +  P
Sbjct: 131 SGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPP 190

Query: 200 APKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPK 259
            P  + S  A A+   ++E+ LP   P     +      PPAP   +P    VN +  P 
Sbjct: 191 TPLPMHSSKAPAY---NREKPLP---PTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGP- 243

Query: 260 AWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMG 319
                 SG++  PP     P    P   P GPS  P+++   +  +    L    P  + 
Sbjct: 244 ------SGQSLAPPP----PPYRQPPGVPNGPS-SPTNESAPELPQRHNSLHRKTPGPVR 292

Query: 320 GQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNG 366
           G A   P    P   S  P      P    P     P P  P   NG
Sbjct: 293 GLAPPPPTSASPSLLSNRPPPPARDP----PSRGAAPPPPPPVIRNG 335



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 104/286 (36%), Gaps = 37/286 (12%)

Query: 92  LPPDLPKPPSPAP-------SSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTR 144
           +PP  P PP P P       ++E P L++  +R   +L  +      L++        T 
Sbjct: 3   IPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKV-------TN 55

Query: 145 RSRAGDPHRSRDRDRATG-GWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKR 203
            +    P   + +  + G G   +  +P+ G   GG   L P  A D      G PA + 
Sbjct: 56  INDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQI 115

Query: 204 LASLNAAAFLKLSQERELPLRLPRAHAEVD-GRSTEPPAPKAPRPKWPKVNGKNYPKAWQ 262
            +S  AA    +S     P        + D  R++ P  P+  RP  P ++  N   +  
Sbjct: 116 PSSRAAAPRPPVSAASGRP------QDDTDSSRASLPELPRMQRPSLPDLSRPNTTSS-T 168

Query: 263 GASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQA 322
           G     +A PP   G      P+  P   S  P++       E PL   P   L  G + 
Sbjct: 169 GMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYN-----REKPLPPTPGQRLHPGREG 223

Query: 323 ALKPEPGRPGEESPAPKQELHQPSF------PTPQLSPLPMPGNPA 362
              P P +P    P+P      PS       P P   P  +P  P+
Sbjct: 224 PPAPPPVKP---PPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPS 266


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 140/601 (23%), Positives = 199/601 (33%), Gaps = 138/601 (22%)

Query: 43  ESPGHLTGRRKNYP----------LRKRPLVPEKPKACKVLLTRLENVAGPRSADEADEL 92
           ++P  L GR +  P           R +P + E P+  ++   +L  V  P+       L
Sbjct: 103 QAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPL 162

Query: 93  PPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPH 152
            P LP+  +  P++E+ G  +  +   +S  +           + +S + T R  A  P 
Sbjct: 163 RPGLPRTEAQ-PAAEELGFHRCFQEPPSSFTST----------NYTSPSATPRPPAPGPP 211

Query: 153 RSRDRD----------RATGG--WSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPA 200
           +SR             +A+G   W  + +    G    G     PEP P +G R  G P 
Sbjct: 212 QSRGTSPLQPGSYPEYQASGADSWPPAAENSFPG-ANFGVPPAEPEPIP-KGSRPGGSP- 268

Query: 201 PKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEP-PAPKAPRP--KWPKVNGKNY 257
                             R +  + P     + G ST+P PA  A       P V   + 
Sbjct: 269 ------------------RGVSFQFP--FPALHGASTKPFPADVAGHAFTNGPLVFAFHQ 308

Query: 258 PKAWQGASSGEAAGPPGWQGCPDEPWPSATPC---GPSVQPSHQPLSKALESP----LGL 310
           P   QGA   EA G       P +P PS  PC    P     H  LS AL SP       
Sbjct: 309 P---QGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAP 365

Query: 311 RPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVG 370
           RP    L      + PE  RP    P+ +  L     P   L     PG     +G+   
Sbjct: 366 RPFSDSLHKSLTKILPE--RP----PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTS 419

Query: 371 PELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEE---GLLLAPSSVPSGTP 427
           P            G    +     P P        P AAP+     G L A  S+     
Sbjct: 420 P------------GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSM----F 463

Query: 428 FQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPY------KMPFAAEGCR 481
           F   P    R C  +             PL       T    P+      ++PF A G  
Sbjct: 464 FNGQPSPGQRLCLPQSA-----------PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPE 512

Query: 482 SLGQLEFPLPEAGHPASPAHPLL-------GCPV-----PSVPPAAEPV----------P 519
             G  +  L  AG    P   L        G P          P A+P+          P
Sbjct: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572

Query: 520 HLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPR 579
           H  TP+  P  V  A P  +  PS + +    GS+C  ++ S  +  P++P     Q P 
Sbjct: 573 H-GTPSLPPPRVVGASPSESPLPSPATN--TAGSTC--SSLSPMSSSPANPSSEESQLPG 627

Query: 580 P 580
           P
Sbjct: 628 P 628



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 114/493 (23%), Positives = 157/493 (31%), Gaps = 135/493 (27%)

Query: 12   LSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKNYPLRKRPLVPEKPKACK 71
            L S +T     ++ +  N E     ++    E P    G    +PL+ +  V  + KA  
Sbjct: 840  LDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKA-- 897

Query: 72   VLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSED-PGLAQPRKRRLASLNAEAL--- 127
                                LP   P P +P P     P   +P+ R L     EA    
Sbjct: 898  -----------------PPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPS 940

Query: 128  --------NNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGG 179
                      L L R+D  S      S +G            GG  +S  RPR  D G G
Sbjct: 941  QGRQQRRGKQLKLFRKDLDSGGAAEGSGSG------------GGGRASGLRPRRND-GLG 987

Query: 180  SRDLSPEPAP----DEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRL-PRAHAEVDG 234
             R   P P P     + P    DPAP+   +       + S+ R LP R  PR      G
Sbjct: 988  ER---PPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGG 1044

Query: 235  R---------------------STEPPAPKAPRPKWPKVNG-------KNYPKAWQGASS 266
                                  ++E    + P P+ P   G       +   +  QG   
Sbjct: 1045 AWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPRE 1104

Query: 267  GEAAGP-------PGWQGCPDEP-WPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLM 318
             E   P        G  G P  P  P  +  GP   P  +  S++LE+            
Sbjct: 1105 DEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET------------ 1152

Query: 319  GGQAALKPEPGRPGEESPAPKQELH-----------QPSFPTPQLSPLPMPGNPADYNGL 367
             G AA +  P      S APK  L            +PS   PQ +  P     +     
Sbjct: 1153 -GAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEES----- 1206

Query: 368  CVGPELT----ALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVP 423
               P+ T    AL S    C  E     G SP  ++PE    P  + H+ G     +  P
Sbjct: 1207 --APDSTEFTEALRSPPAACAGE----MGASPGLLIPE---QPPPSRHDTG-----TPKP 1252

Query: 424  SGTPFQHPPWGSS 436
            SG+     P GSS
Sbjct: 1253 SGSLANTAPHGSS 1265



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 40/168 (23%), Positives = 59/168 (35%), Gaps = 15/168 (8%)

Query: 92   LPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDP 151
            + P  PK   P PSS+  G  +P  +       +  +  L     T+    +  SR+  P
Sbjct: 3691 MKPATPKA-KPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAP 3749

Query: 152  HRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAA 211
             R   R +A     S  K PR     G    L P+   +   +R     P    S +  +
Sbjct: 3750 ERLPARAQA----KSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGS 3805

Query: 212  FLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPK 259
            F +     + P R PR  A           P    P  PK N +N P+
Sbjct: 3806 FGRAPSAPDKPPRTPRKQA----------TPSRVLPTKPKPNSQNKPR 3843



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 83/356 (23%), Positives = 104/356 (29%), Gaps = 97/356 (27%)

Query: 87  DEADELPPDLPKPPSPAPSS---------------------EDPGLAQPRKRRLASLNAE 125
           +EA    P  P P  PAPS                        PG A    R  +    +
Sbjct: 315 EEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHK 374

Query: 126 ALNNLLLEREDTSS--LAGTR--------RSRAGDPHRSRDRDRATGGWSSSKKRP---- 171
           +L  +L ER  ++   L  TR        R   G  +R+   D + G   +    P    
Sbjct: 375 SLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPP 434

Query: 172 -RLGDLGGGSRDLSPEPAPDEGPRR-------DGDPAPKRLASLNAAAFLKLSQERELPL 223
            RL  L   +   +P P P  GP         +G P+P +   L  +A L   Q   LP 
Sbjct: 435 ARLPQLWDPTA--APYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQV--LPT 490

Query: 224 RLPRAHA--------------EVDGRS-----TEPPAPKAPRPKWPKV------------ 252
             P  H               E  G S     T    P  PR K P V            
Sbjct: 491 ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP-GPREKLPAVRSSQGGSPALFT 549

Query: 253 -NGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLR 311
            NG   P A Q    G A       G P  P P      PS  P   P +    S     
Sbjct: 550 YNGMTDPGA-QPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCS-- 606

Query: 312 PHLPLLMGGQAALKPEPGRPGEESP------APKQELHQPSFPTPQLSPLPMPGNP 361
                     + +   P  P  E         P    H P+ P    SP P P  P
Sbjct: 607 --------SLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPP 654


>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
          Length = 1334

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 152/604 (25%), Positives = 197/604 (32%), Gaps = 98/604 (16%)

Query: 8   SLPMLSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKN-YPLRKRPLVPEK 66
           SLP +   LT  + P +   S      EG  P  P   GH  G+R+  +  + RP  P  
Sbjct: 114 SLPQIP--LTPLQPPSEPPASPSLSSTEG--PAAPLPLGHCAGQREVCWEQQLRPGGPGP 169

Query: 67  PKACKVLLTRLENVAGP--------RSADEADEL---PPDLP-KPPSPAPSSEDP----- 109
           P A    L  L              R+ +E D L    P  P +PP   P S +P     
Sbjct: 170 PAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGEL 229

Query: 110 -GLAQPRKRRLASLNAEALNNL--LLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSS 166
            G  QP     A        NL  LL  E      G           SR   +A G  S 
Sbjct: 230 CGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSG 289

Query: 167 SKKRPRLGDLGGGSRDLSPEPA-PDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRL 225
               P     G  S   S E   P+E P  D          LN    L+   E  L   L
Sbjct: 290 PNCAP-----GSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLE-DTESYLQAFL 343

Query: 226 PRAHAEVDGRSTEPPAPKAPRPKWPKVN-GKNYPK-AWQGAS----------SGEAAGP- 272
             A   ++G    P    +P    P+++  K  PK AW G +          + E  GP 
Sbjct: 344 AGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPL 403

Query: 273 ---PGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPG 329
                + G  D P  S        +P H   S  ++S L + P  P     Q  L P P 
Sbjct: 404 PFLSMFMGAGDAPLGS--------RPGHPHSSSQVKSKLQIGPPSP--GEAQGPLLPSPA 453

Query: 330 RPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQ 389
           R  +    P      PS   PQLSP  +P N                    + C   G  
Sbjct: 454 RGLKFLKLPPTSEKSPSPGGPQLSP-QLPRNSR------------------IPCRNSG-- 492

Query: 390 CGGYSPCPMLPE-----GKLSPVAAPHEEGLLLAPS---SVPSGTPFQHPPWGSSRYCSS 441
               SP P+L       G+LSP  A   +GL  +PS   + P  T  + P    S   S 
Sbjct: 493 -SDGSPSPLLARRGLGGGELSPEGA---QGLPTSPSPCYTTPDSTQLRPPQSALSTTLSP 548

Query: 442 EDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHP-ASPA 500
                  Y    +L LS     T  G  P   P   +   +  QL   +P+A     SP 
Sbjct: 549 GPVVSPCYE--NILDLS---RSTFRGPSPEPPPSPLQ-VPTYPQLTLEVPQAPEVLRSPG 602

Query: 501 HPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTAR 560
            P   C   S P  +     L    SE     R  P ++       SG R G       R
Sbjct: 603 VPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLR 662

Query: 561 SKAA 564
            + A
Sbjct: 663 DRLA 666



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 62/284 (21%), Positives = 85/284 (29%), Gaps = 62/284 (21%)

Query: 36   GVEPGMPESPGHLTGRRKNYPLRK---RPLVPEKPKACKVLLTRLEN-----------VA 81
            G  PG P S     GRR+  P       P+      AC  L   L++            +
Sbjct: 1081 GKPPGKPSSE---PGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSS 1137

Query: 82   GPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLA 141
            G  S +     PP L  PP   P+   P    PR+          +  LL+     S  A
Sbjct: 1138 GTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPA 1197

Query: 142  GTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAP 201
                  A   HR                                E  PD+     G   P
Sbjct: 1198 FPALLPAAPGHRGH------------------------------ETCPDDPCEDPGPTPP 1227

Query: 202  KRLASLNAAAFLKLSQERELPLRLPRAHAE----------VDGRSTEPPAPKAPRPKWPK 251
             +LA        + +     PL  P    E          VD + ++ P+  +P P+ P 
Sbjct: 1228 VQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPP 1287

Query: 252  VNGKNYPKAWQGASSGEAA--GPPGW---QGCPDEPWPSATPCG 290
              G   P     A  G  A  GPPG    +   D  + S + CG
Sbjct: 1288 FGGSRTPSTSDMAEEGRVASGGPPGLETSESLSDSLYDSLSSCG 1331



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 7/95 (7%)

Query: 489  PLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGS--- 545
            P P  G       PL GC  P   P++EP    + P+ +  ++A   P S     GS   
Sbjct: 1063 PWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSED--SLAEPVPTSHFTACGSLTR 1120

Query: 546  --KSGLRTGSSCRHTARSKAARRPSHPKQPRVQRP 578
               SG+ T     H +    ++     K PR+  P
Sbjct: 1121 TLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPP 1155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,407,083
Number of Sequences: 37866
Number of extensions: 2792669
Number of successful extensions: 19227
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 1065
Number of HSP's that attempted gapping in prelim test: 14210
Number of HSP's gapped (non-prelim): 5363
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.