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Search of human proteins with 7662078
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
(1564 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 3117 0.0
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 63 3e-09
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 62 3e-09
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 62 3e-09
gi|83415184 transmembrane and tetratricopeptide repeat containin... 57 1e-07
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 56 2e-07
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 55 5e-07
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 55 7e-07
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 52 4e-06
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 52 4e-06
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 51 8e-06
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 51 8e-06
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 51 8e-06
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 47 1e-04
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 47 1e-04
gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens] 47 1e-04
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho... 47 1e-04
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap... 47 1e-04
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap... 47 1e-04
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap... 47 1e-04
gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H... 47 1e-04
gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho... 47 1e-04
gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa... 45 4e-04
gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa... 45 4e-04
gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa... 45 4e-04
gi|224809432 transmembrane and tetratricopeptide repeat containi... 45 4e-04
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 44 0.001
gi|118402596 cell division cycle protein 23 [Homo sapiens] 44 0.001
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 44 0.002
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 43 0.003
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 3117 bits (8080), Expect = 0.0
Identities = 1564/1564 (100%), Positives = 1564/1564 (100%)
Query: 1 MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQ 60
MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQ
Sbjct: 1 MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQ 60
Query: 61 SAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCK 120
SAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCK
Sbjct: 61 SAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCK 120
Query: 121 KLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQ 180
KLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQ
Sbjct: 121 KLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQ 180
Query: 181 LLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPL 240
LLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPL
Sbjct: 181 LLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPL 240
Query: 241 EVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLK 300
EVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLK
Sbjct: 241 EVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLK 300
Query: 301 ESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEAL 360
ESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEAL
Sbjct: 301 ESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEAL 360
Query: 361 IKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLA 420
IKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLA
Sbjct: 361 IKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLA 420
Query: 421 EVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALT 480
EVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALT
Sbjct: 421 EVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALT 480
Query: 481 HFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVE 540
HFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVE
Sbjct: 481 HFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVE 540
Query: 541 LEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNC 600
LEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNC
Sbjct: 541 LEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNC 600
Query: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK
Sbjct: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
Query: 661 KKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLA 720
KKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLA
Sbjct: 661 KKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLA 720
Query: 721 GDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWC 780
GDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWC
Sbjct: 721 GDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWC 780
Query: 781 DLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGI 840
DLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGI
Sbjct: 781 DLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGI 840
Query: 841 GNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIG 900
GNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIG
Sbjct: 841 GNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIG 900
Query: 901 QALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMN 960
QALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMN
Sbjct: 901 QALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMN 960
Query: 961 AIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYN 1020
AIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYN
Sbjct: 961 AIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYN 1020
Query: 1021 VAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSI 1080
VAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSI
Sbjct: 1021 VAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSI 1080
Query: 1081 VESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATL 1140
VESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATL
Sbjct: 1081 VESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATL 1140
Query: 1141 SKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLS 1200
SKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLS
Sbjct: 1141 SKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLS 1200
Query: 1201 RVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQ 1260
RVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQ
Sbjct: 1201 RVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQ 1260
Query: 1261 KAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENY 1320
KAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENY
Sbjct: 1261 KAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENY 1320
Query: 1321 NQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKP 1380
NQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKP
Sbjct: 1321 NQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKP 1380
Query: 1381 LPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKL 1440
LPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKL
Sbjct: 1381 LPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKL 1440
Query: 1441 SSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARE 1500
SSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARE
Sbjct: 1441 SSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARE 1500
Query: 1501 TRRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQR 1560
TRRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQR
Sbjct: 1501 TRRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQR 1560
Query: 1561 LSSQ 1564
LSSQ
Sbjct: 1561 LSSQ 1564
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 62.8 bits (151), Expect = 3e-09
Identities = 136/671 (20%), Positives = 254/671 (37%), Gaps = 130/671 (19%)
Query: 244 CLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESP 303
C L+E G+ D+ ++ + P L+G + K Y A+ + L+ +P
Sbjct: 136 CFCLLE-GDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNP 194
Query: 304 VCTSGW-YHLAEAQVKMHRPKEAVLSCSQALKIVDN-LGASGNSLYQRNLCLHLKAEALI 361
C + + VK+++ ++A L+ S+AL++ +GA L A++
Sbjct: 195 GCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGA-------------LVGLAVL 241
Query: 362 KLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAE 421
+L++ +AD+I + L S AY S + + D ++
Sbjct: 242 ELNN--------------KEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSK 287
Query: 422 V-HALEALIHFTKKDYLQAEKCFQRA----LEKDTEVA-EYHYQLGLTYWFMGEETRKDK 475
V H H T+ + +QAE C+Q A +++D + A +Y+YQ
Sbjct: 288 VQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQ---------------- 331
Query: 476 TKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAV 535
T F ++ + + G Y+ YR GDK A C+ K + + E+
Sbjct: 332 ---ATQFASSSFVLPFFGLGQMYI---YR---GDKENASQCFEKVLKAYPNNYETMKILG 382
Query: 536 DLSVELEDME---MALAILTTVTQKASAGTAKWAWLRRGLYYL----KAGQHSQAVADLQ 588
L ED E +A L VT++ W L + L + A LQ
Sbjct: 383 SLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQ 442
Query: 589 AALRAD--PKDFNCWESLGEAYLSRGGYTTALKSF------TKASELNPESIYSV----- 635
++AD P+ N ++G + G A K F KA + E Y+
Sbjct: 443 EKVQADVPPEILN---NVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTT 499
Query: 636 -FKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVD 694
+ +A + + + ++ EA Y+ I+++ +YV +C+L + A +
Sbjct: 500 SYNLARLYEAMCEFHEAEKLYKNILREHPNYV-------DCYLRLGAMA-------RDKG 545
Query: 695 YIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLK 754
+A ++F ALQ D W L G+ P GQK+ +++LK
Sbjct: 546 NFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGP------------GQKKFERILK 593
Query: 755 KNELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCL 814
+ +++ N W Q L + + K +++L
Sbjct: 594 QPS-------TQSDTYSMLALGNVW----------LQTLHQPTRDREKEKRHQDRALAIY 636
Query: 815 KKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTN 874
K+ +R D+ N N +G V + G + A+ F + ++ + W NL +Y+
Sbjct: 637 KQVLRNDAKNLYAANGIGAVLAHKGY--FREARDVFAQVREATADISDVWLNLAHIYVEQ 694
Query: 875 ENIEQAHEAFK 885
+ A + ++
Sbjct: 695 KQYISAVQMYE 705
Score = 36.6 bits (83), Expect = 0.20
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 23 KEALKHC-KTVLKQEKNNYNAWVFIG---VAAAELEQPDQAQSAYKKAAELEPDQLLAWQ 78
KE C + VLK NNY +G A+ + E+ D A+ KK E PD + AW
Sbjct: 357 KENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWI 416
Query: 79 GLANLYEK 86
LA + E+
Sbjct: 417 ELAQILEQ 424
Score = 35.8 bits (81), Expect = 0.33
Identities = 109/530 (20%), Positives = 196/530 (36%), Gaps = 88/530 (16%)
Query: 567 WLRRGLYYLKAGQHSQAVADLQAA-------LRADPKD-FNCWESLGEAYLSRGG----- 613
W+ L Y K G+ + V L+AA R KD C ++L Y+ +
Sbjct: 44 WIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNK 103
Query: 614 ------YTTALKSFTKASELNPESIYSVFKVAAIQQILG-KYKEAVAQYQMIIKKKEDYV 666
T A +T A ++ + A + G K +A AQ+ ++ + + +
Sbjct: 104 DNKKDLITQATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNI 163
Query: 667 PALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT-CALQHRADVS-CLWKLAGDAC 724
PAL LG+ + K DY A+ Y +KAL C + R + C KL
Sbjct: 164 PAL--LGKACISFNKK---DYRG--ALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEK 216
Query: 725 TCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWCDLGI 784
L ++N +G L+G + K+ + + G + RA + ++ +
Sbjct: 217 ARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLA 276
Query: 785 NY------YRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRL----DSNNHLYWNA---- 830
N+ Y + QHLA + +++ + +S + L ++ + D Y+ A
Sbjct: 277 NHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFA 336
Query: 831 --------LGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQ--- 879
G+ Y G+ A CF K +++ N LG LY +E+ E+
Sbjct: 337 SSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDI 396
Query: 880 AHEAFKMAQSLDPSYLMCWIGQALIAE------AVGSYDTMD-LFRHTTELNMHTE---- 928
A K P + WI A I E A+ +Y T + + + ++ E
Sbjct: 397 AKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNN 456
Query: 929 --------GALGYA--YWVCTTLQDKSNRETELYQYNILQ-------------MNAIPAA 965
G LG A Y++ + + K+ E + + YN + M A
Sbjct: 457 VGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEA 516
Query: 966 QVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAED 1015
+ + + NY + LG + EA++ ++ A+ + Q D
Sbjct: 517 EKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPD 566
Score = 34.3 bits (77), Expect = 0.97
Identities = 68/347 (19%), Positives = 129/347 (37%), Gaps = 45/347 (12%)
Query: 833 VVACYSGIGNYALAQHCFIKSIQSEQI---------NAVAWT---NLGVLYLTNENIEQA 880
V A + +GN A+ F+ S+ + NA++ T NL LY +A
Sbjct: 457 VGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEA 516
Query: 881 HEAFKMAQSLDPSYLMCWIGQALIAEAVGS-YDTMDLFRHTTELNMHTEGALGYAYWVCT 939
+ +K P+Y+ C++ +A G+ Y+ D F+ ++N
Sbjct: 517 EKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQIN--------------- 561
Query: 940 TLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQL---- 995
QD + + + ++ + P Q + +++ + ++ML N LQ
Sbjct: 562 --QDHPDAWSLIGNLHLAKQEWGP-GQKKFERILKQPSTQSDTYSMLALGNVWLQTLHQP 618
Query: 996 ---KKEAANAYQRAILLLQTAEDQDTYNV-AIRNYGRLLCSTGEYDKAIQAF---KSTPL 1048
+++ RA+ + + D N+ A G +L G + +A F +
Sbjct: 619 TRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATA 678
Query: 1049 EVLEDIIGFALALFMKGLYKESSKAYERALSIVESEQDKAHILTALAITEYKQGKTDVAK 1108
++ + + A + Y + + YE L Q+ ++ LA +K GK K
Sbjct: 679 DISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQN-TEVVLYLARALFKCGKLQECK 737
Query: 1109 TLLFKCSILKEPTTESL--QALCALGLAMQDATLSKAALNELLKHIK 1153
L K + T + AL LA K+ L E+L +K
Sbjct: 738 QTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVK 784
Score = 33.5 bits (75), Expect = 1.7
Identities = 17/64 (26%), Positives = 33/64 (51%)
Query: 21 EYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGL 80
E+ EA K K +L++ N + ++ +G A + +A +K+A ++ D AW +
Sbjct: 512 EFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLI 571
Query: 81 ANLY 84
NL+
Sbjct: 572 GNLH 575
Score = 33.1 bits (74), Expect = 2.2
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 1075 ERALSIVESEQDKAHILTALAITEYKQGKTDVAKTLL 1111
+ +SI++ E + HI ALA+ YKQGKT+ LL
Sbjct: 28 DEVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLL 64
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 62.4 bits (150), Expect = 3e-09
Identities = 68/300 (22%), Positives = 121/300 (40%), Gaps = 15/300 (5%)
Query: 402 FDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLG 461
F++A + + L +Y +L V EA I + +A + RAL A H L
Sbjct: 204 FEKAVTLDPNFLDAYINLGNV-LKEARI------FDRAVAAYLRALSLSPNHAVVHGNLA 256
Query: 462 LTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAF 521
Y+ G A+ + +A L + +C L + ++ G A CY A
Sbjct: 257 CVYYEQGLIDL-----AIDTYRRAIELQPHFPDAYCNLANALKEK-GSVAEAEDCYNTAL 310
Query: 522 ELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHS 581
L T A+S ++ E ++E A+ + + A + L L + G+
Sbjct: 311 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ--QQGKLQ 368
Query: 582 QAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAI 641
+A+ + A+R P + + ++G AL+ +T+A ++NP + +A+I
Sbjct: 369 EALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 428
Query: 642 QQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALE 701
+ G EA+A Y+ +K K D+ A L C ++ D K V + LE
Sbjct: 429 HKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLE 488
Score = 49.3 bits (116), Expect = 3e-05
Identities = 54/265 (20%), Positives = 107/265 (40%), Gaps = 28/265 (10%)
Query: 820 LDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQ 879
L N LY + +G A+ C++K+I+++ AVAW+NLG ++ I
Sbjct: 140 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 199
Query: 880 AHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCT 939
A F+ A +LDP++L +I + + +D + + L++ A+ + C
Sbjct: 200 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRA-VAAYLRALSLSPNHAVVHGNLACV 258
Query: 940 TLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEA 999
Y+ ++ + A + +E ++ A+ L + EA
Sbjct: 259 -----------YYEQGLIDL-----AIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEA 302
Query: 1000 ANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDII---- 1055
+ Y A+ L T D ++ N + G ++A++ ++ LEV +
Sbjct: 303 EDCYNTALRLCPTHAD------SLNNLANIKREQGNIEEAVRLYRKA-LEVFPEFAAAHS 355
Query: 1056 GFALALFMKGLYKESSKAYERALSI 1080
A L +G +E+ Y+ A+ I
Sbjct: 356 NLASVLQQQGKLQEALMHYKEAIRI 380
Score = 45.4 bits (106), Expect = 4e-04
Identities = 79/388 (20%), Positives = 147/388 (37%), Gaps = 75/388 (19%)
Query: 566 AWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKAS 625
A+ G Y + GQ +A+ + ALR P + + +L A ++ G A++++ A
Sbjct: 81 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 140
Query: 626 ELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALV 685
+ NP+ + + + LG+ +EA A Y I+ + ++ A LG + L
Sbjct: 141 QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL- 199
Query: 686 DYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAG--DACTCLY----AVAPSKVNVHV 739
A+ + EKA+ L ++ + K A D Y +++P+ VH
Sbjct: 200 ------AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 253
Query: 740 LGVLLGQKEG--------------------------KQVLKKNELLHLGGRCYGRALKLM 773
+ ++G LK+ + CY AL+L
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLC 313
Query: 774 STS----NTWCDL---------GINYYRQA----QHLAETGSNMNDLKE---LLEKSLHC 813
T N ++ + YR+A A SN+ + + L+++L
Sbjct: 314 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH 373
Query: 814 LKKAVRLDSNNHLYWNALGVVACYSGIGNYAL-------AQHCFIKSIQSEQINAVAWTN 866
K+A+R+ YS +GN A C+ ++IQ A A +N
Sbjct: 374 YKEAIRISPT---------FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 424
Query: 867 LGVLYLTNENIEQAHEAFKMAQSLDPSY 894
L ++ + NI +A +++ A L P +
Sbjct: 425 LASIHKDSGNIPEAIASYRTALKLKPDF 452
Score = 33.1 bits (74), Expect = 2.2
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 10/92 (10%)
Query: 1340 GRISEAETLCTKNLKSNPDQPAVILLLRQV--QCKPLLESQKPLPDAVLEELQKTVMSNS 1397
G AE C + + PD V+LLL + QC+ L D + N
Sbjct: 25 GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRL--------DRSAHFSTLAIKQNP 76
Query: 1398 TSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQL 1429
A+ L +VY+ +G ++ A YR +L+L
Sbjct: 77 LLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 108
Score = 32.0 bits (71), Expect = 4.8
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 25 ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLY 84
A+ H + + + N +A++ +G E D+A +AY +A L P+ + LA +Y
Sbjct: 200 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 259
Query: 85 EKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKL---------VDLYYQEKKHLEV 135
+ I+ D Y++ ++L +C++ L D Y +
Sbjct: 260 YEQGLIDLAID---TYRRAIELQPHF-PDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 315
Query: 136 -ARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNN 176
A + + L ++EQG EE +L+RK + E +N
Sbjct: 316 HADSLNNLANIKREQG-NIEEAVRLYRKALEVFPEFAAAHSN 356
Score = 32.0 bits (71), Expect = 4.8
Identities = 35/169 (20%), Positives = 72/169 (42%), Gaps = 12/169 (7%)
Query: 357 AEALIKLSDYDSSEEAIRTLDQI--SDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLS 414
A AL + +E+ T ++ + AD++ L +K R +G+ +EA ++ L
Sbjct: 290 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIK----REQGNIEEAVRLYRKALE 345
Query: 415 SYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKD 474
+P+ A H+ A + + +A ++ A+ A+ + +G T + +D
Sbjct: 346 VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTL-----KEMQD 400
Query: 475 KTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFEL 523
AL + +A +++ L ++D G+ A YR A +L
Sbjct: 401 VQGALQCYTRAIQINPAFADAHSNLASIHKD-SGNIPEAIASYRTALKL 448
Score = 31.6 bits (70), Expect = 6.3
Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 14/135 (10%)
Query: 23 KEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLAN 82
+EAL H K ++ +A+ +G E++ A Y +A ++ P A LA+
Sbjct: 368 QEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLAS 427
Query: 83 LYEKYNHI-----------NAKDDLPGVYQKLLDLYESV-DKQKWCDVCKKLVDLYYQ-- 128
+++ +I K D P Y L + V D + + KKLV +
Sbjct: 428 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQL 487
Query: 129 EKKHLEVARTWHKLI 143
EK L H ++
Sbjct: 488 EKNRLPSVHPHHSML 502
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 62.4 bits (150), Expect = 3e-09
Identities = 68/300 (22%), Positives = 121/300 (40%), Gaps = 15/300 (5%)
Query: 402 FDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLG 461
F++A + + L +Y +L V EA I + +A + RAL A H L
Sbjct: 214 FEKAVTLDPNFLDAYINLGNV-LKEARI------FDRAVAAYLRALSLSPNHAVVHGNLA 266
Query: 462 LTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAF 521
Y+ G A+ + +A L + +C L + ++ G A CY A
Sbjct: 267 CVYYEQGLIDL-----AIDTYRRAIELQPHFPDAYCNLANALKEK-GSVAEAEDCYNTAL 320
Query: 522 ELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHS 581
L T A+S ++ E ++E A+ + + A + L L + G+
Sbjct: 321 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ--QQGKLQ 378
Query: 582 QAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAI 641
+A+ + A+R P + + ++G AL+ +T+A ++NP + +A+I
Sbjct: 379 EALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 438
Query: 642 QQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALE 701
+ G EA+A Y+ +K K D+ A L C ++ D K V + LE
Sbjct: 439 HKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLE 498
Score = 49.3 bits (116), Expect = 3e-05
Identities = 54/265 (20%), Positives = 107/265 (40%), Gaps = 28/265 (10%)
Query: 820 LDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQ 879
L N LY + +G A+ C++K+I+++ AVAW+NLG ++ I
Sbjct: 150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 209
Query: 880 AHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCT 939
A F+ A +LDP++L +I + + +D + + L++ A+ + C
Sbjct: 210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRA-VAAYLRALSLSPNHAVVHGNLACV 268
Query: 940 TLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEA 999
Y+ ++ + A + +E ++ A+ L + EA
Sbjct: 269 -----------YYEQGLIDL-----AIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEA 312
Query: 1000 ANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDII---- 1055
+ Y A+ L T D ++ N + G ++A++ ++ LEV +
Sbjct: 313 EDCYNTALRLCPTHAD------SLNNLANIKREQGNIEEAVRLYRKA-LEVFPEFAAAHS 365
Query: 1056 GFALALFMKGLYKESSKAYERALSI 1080
A L +G +E+ Y+ A+ I
Sbjct: 366 NLASVLQQQGKLQEALMHYKEAIRI 390
Score = 45.4 bits (106), Expect = 4e-04
Identities = 79/388 (20%), Positives = 147/388 (37%), Gaps = 75/388 (19%)
Query: 566 AWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKAS 625
A+ G Y + GQ +A+ + ALR P + + +L A ++ G A++++ A
Sbjct: 91 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 150
Query: 626 ELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALV 685
+ NP+ + + + LG+ +EA A Y I+ + ++ A LG + L
Sbjct: 151 QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL- 209
Query: 686 DYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAG--DACTCLY----AVAPSKVNVHV 739
A+ + EKA+ L ++ + K A D Y +++P+ VH
Sbjct: 210 ------AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 263
Query: 740 LGVLLGQKEG--------------------------KQVLKKNELLHLGGRCYGRALKLM 773
+ ++G LK+ + CY AL+L
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLC 323
Query: 774 STS----NTWCDL---------GINYYRQA----QHLAETGSNMNDLKE---LLEKSLHC 813
T N ++ + YR+A A SN+ + + L+++L
Sbjct: 324 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH 383
Query: 814 LKKAVRLDSNNHLYWNALGVVACYSGIGNYAL-------AQHCFIKSIQSEQINAVAWTN 866
K+A+R+ YS +GN A C+ ++IQ A A +N
Sbjct: 384 YKEAIRISPT---------FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 434
Query: 867 LGVLYLTNENIEQAHEAFKMAQSLDPSY 894
L ++ + NI +A +++ A L P +
Sbjct: 435 LASIHKDSGNIPEAIASYRTALKLKPDF 462
Score = 33.1 bits (74), Expect = 2.2
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 10/92 (10%)
Query: 1340 GRISEAETLCTKNLKSNPDQPAVILLLRQV--QCKPLLESQKPLPDAVLEELQKTVMSNS 1397
G AE C + + PD V+LLL + QC+ L D + N
Sbjct: 35 GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRL--------DRSAHFSTLAIKQNP 86
Query: 1398 TSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQL 1429
A+ L +VY+ +G ++ A YR +L+L
Sbjct: 87 LLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 118
Score = 32.0 bits (71), Expect = 4.8
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 25 ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLY 84
A+ H + + + N +A++ +G E D+A +AY +A L P+ + LA +Y
Sbjct: 210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269
Query: 85 EKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKL---------VDLYYQEKKHLEV 135
+ I+ D Y++ ++L +C++ L D Y +
Sbjct: 270 YEQGLIDLAID---TYRRAIELQPHF-PDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Query: 136 -ARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNN 176
A + + L ++EQG EE +L+RK + E +N
Sbjct: 326 HADSLNNLANIKREQG-NIEEAVRLYRKALEVFPEFAAAHSN 366
Score = 32.0 bits (71), Expect = 4.8
Identities = 35/169 (20%), Positives = 72/169 (42%), Gaps = 12/169 (7%)
Query: 357 AEALIKLSDYDSSEEAIRTLDQI--SDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLS 414
A AL + +E+ T ++ + AD++ L +K R +G+ +EA ++ L
Sbjct: 300 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIK----REQGNIEEAVRLYRKALE 355
Query: 415 SYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKD 474
+P+ A H+ A + + +A ++ A+ A+ + +G T + +D
Sbjct: 356 VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTL-----KEMQD 410
Query: 475 KTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFEL 523
AL + +A +++ L ++D G+ A YR A +L
Sbjct: 411 VQGALQCYTRAIQINPAFADAHSNLASIHKD-SGNIPEAIASYRTALKL 458
Score = 31.6 bits (70), Expect = 6.3
Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 14/135 (10%)
Query: 23 KEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLAN 82
+EAL H K ++ +A+ +G E++ A Y +A ++ P A LA+
Sbjct: 378 QEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLAS 437
Query: 83 LYEKYNHI-----------NAKDDLPGVYQKLLDLYESV-DKQKWCDVCKKLVDLYYQ-- 128
+++ +I K D P Y L + V D + + KKLV +
Sbjct: 438 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQL 497
Query: 129 EKKHLEVARTWHKLI 143
EK L H ++
Sbjct: 498 EKNRLPSVHPHHSML 512
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 57.4 bits (137), Expect = 1e-07
Identities = 92/427 (21%), Positives = 160/427 (37%), Gaps = 48/427 (11%)
Query: 298 GLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKI-------VDNLG------ASGN 344
G++ P Y+ A R KEA+ ALK+ ++NLG A
Sbjct: 367 GVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEAK 426
Query: 345 SLYQRNLCLHLKAEALI-----KLSDYDSSEEAIRTL-DQISDADNIPGLLVLKSLAYRN 398
YQR L LH + + L + EEAI L D I +
Sbjct: 427 MYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAE 486
Query: 399 KGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHY 458
+ F EA +I + + + PD +++H + +A +Q+A++
Sbjct: 487 QERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMV 546
Query: 459 QLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYR 518
LG Y +GE + ++ + K A + ++ LG Y + G A Y+
Sbjct: 547 NLGRLYRSLGENSMAEE------WYKRALQVAHKAEILSPLGALYYNT-GRYEEALQIYQ 599
Query: 519 KAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAG 578
+A L + E A + + + A + + + + + L Y K
Sbjct: 600 EAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLL--SAIYSKQE 657
Query: 579 QHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTT-------ALKSFTKASELNPES 631
H +A+ + AL+ PKD + E + ++G A +S+ A +LNP+
Sbjct: 658 NHDKALDAIDKALQLKPKDPKV---ISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQ 714
Query: 632 IYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGK 691
+ + IQ I GKY A A Y+ AL+ + + L+ A +D L+ +
Sbjct: 715 AQAWMNMGGIQHIKGKYVSARAYYER----------ALQLVPDSKLLKENLAKLDRLEKR 764
Query: 692 AVDYIEK 698
+ EK
Sbjct: 765 LQEVREK 771
Score = 53.9 bits (128), Expect = 1e-06
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 20/240 (8%)
Query: 965 AQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIR 1024
A +L ++ +A A++ L L + KEA YQ I + D +N
Sbjct: 459 AITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIK--NCPDSSDLHN---- 512
Query: 1025 NYGRLLCSTGEYDKAI----QAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSI 1080
NYG L TG +KA+ QA K +P + ++ G + + Y+RAL +
Sbjct: 513 NYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVA-MVNLGRLYRSLGENSMAEEWYKRALQV 571
Query: 1081 VESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATL 1140
KA IL+ L Y G+ + A + + + L +P+ L+ A LA+ T
Sbjct: 572 AH----KAEILSPLGALYYNTGRYEEALQIYQEAAAL-QPSQRELRLALAQVLAVMGQTK 626
Query: 1141 SKAALNELLKHIKHKDSNYQRCL-LTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLL 1199
++ HI +++ C L SAIY+ Q I KA+ P DP + S L
Sbjct: 627 EA---EKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISEL 683
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/304 (20%), Positives = 115/304 (37%), Gaps = 35/304 (11%)
Query: 254 TDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLA 313
T E + Y R +++ + L LG +K E+A+ L + +K P + LA
Sbjct: 422 TAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLA 481
Query: 314 EAQVKMHRPKEA-------VLSCSQALKIVDNLGA---------SGNSLYQRNLCLHLKA 357
+ R KEA + +C + + +N G + YQ+ + L
Sbjct: 482 SLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSH 541
Query: 358 EALI--------KLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIM 409
+ L + +EE + Q++ I L Y N G ++EA +I
Sbjct: 542 HVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPL---GALYYNTGRYEEALQIY 598
Query: 410 EDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGE 469
++ + P E+ A + +AEK + ++T E + L Y
Sbjct: 599 QEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIY----- 653
Query: 470 ETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKN---RARGCYRKAFELDDT 526
+++ KAL KA +L KV L + + ++N +A YR A +L+
Sbjct: 654 SKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPD 713
Query: 527 DAES 530
A++
Sbjct: 714 QAQA 717
Score = 37.0 bits (84), Expect = 0.15
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 25/235 (10%)
Query: 1222 HILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQKAALLSPGDPAIWAGLMAACH 1281
H+ N G+ LY ++ + +S AE+ AL+ KA +LSP + A
Sbjct: 542 HVAMVNLGR---LYRSLGE----NSMAEEWYKRALQVAHKAEILSP----LGALYYNTGR 590
Query: 1282 ADDKLALVNNT---QPKRIDLYLALLS--AVSASIKDEKFFENYNQS-----LEKWSLSQ 1331
++ L + QP + +L LAL AV K+ + N+ S LE + L
Sbjct: 591 YEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLS 650
Query: 1332 AVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKPLPDAVLEELQK 1391
A+ + +A K L+ P P VI L + L E L D E +
Sbjct: 651 AIYSKQENH--DKALDAIDKALQLKPKDPKVISELFFTKGNQLREQN--LLDKAFESYRV 706
Query: 1392 TVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKLSSLLRL 1446
V N AW + + +G +A Y ++LQL L+ L RL
Sbjct: 707 AVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRL 761
Score = 35.0 bits (79), Expect = 0.57
Identities = 25/104 (24%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 806 LLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWT 865
L EK++ ++A++L ++H+ LG + Y +G ++A+ + +++Q A +
Sbjct: 523 LPEKAVAHYQQAIKLSPSHHVAMVNLGRL--YRSLGENSMAEEWYKRALQVAH-KAEILS 579
Query: 866 NLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVG 909
LG LY E+A + ++ A +L PS + A + +G
Sbjct: 580 PLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMG 623
Score = 31.6 bits (70), Expect = 6.3
Identities = 96/474 (20%), Positives = 183/474 (38%), Gaps = 87/474 (18%)
Query: 436 YLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKV 495
+L E F+ ++ A+ HY F+ ++ R + A+ H+ A +L
Sbjct: 357 WLSRESLFRSGVQTLPHNAKVHYNYAN---FLKDQGRNKE--AIYHYRTALKLYPRHASA 411
Query: 496 FCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVT 555
LG RD A+ Y++A +L + A +L L+ E +T +
Sbjct: 412 LNNLGTLTRDTA----EAKMYYQRALQLHP---QHNRALFNLGNLLKSQEKKEEAITLLK 464
Query: 556 QKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYT 615
G + + A + L A+L A+ + F E + Y
Sbjct: 465 DSIKYGP----------------EFADAYSSL-ASLLAEQERFKEAEEI---------YQ 498
Query: 616 TALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGEC 675
T +K+ +S+L+ Y VF V G ++AVA YQ IK + A+ LG
Sbjct: 499 TGIKNCPDSSDLHNN--YGVFLVDT-----GLPEKAVAHYQQAIKLSPSHHVAMVNLGRL 551
Query: 676 HLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADV----SCLWKLAG--DACTCLY- 728
+ + + ++ A ++ ++AL+ + H+A++ L+ G + +Y
Sbjct: 552 YRSLGENSM-------AEEWYKRALQ-----VAHKAEILSPLGALYYNTGRYEEALQIYQ 599
Query: 729 ---AVAPSKVNV-----HVLGVLLGQKEGKQVLKKNELLHLGG-RCYGRALKLMSTSNTW 779
A+ PS+ + VL V+ KE +++ G CY R L + +
Sbjct: 600 EAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECY-RLLSAIYSKQEN 658
Query: 780 CDLGINYYRQAQHLAETGSNM---------NDLKE--LLEKSLHCLKKAVRLDSNNHLYW 828
D ++ +A L + N L+E LL+K+ + AV+L+ + W
Sbjct: 659 HDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAW 718
Query: 829 NALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHE 882
+G + G Y A+ + +++Q + + NL L + +++ E
Sbjct: 719 MNMGGIQHIK--GKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 770
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 56.2 bits (134), Expect = 2e-07
Identities = 89/388 (22%), Positives = 155/388 (39%), Gaps = 37/388 (9%)
Query: 286 KKYEDAVRNLTEGLKESPVCTSGWYHLA-----EAQVKMHRPKEAVLSCSQALKIVDNLG 340
KK DA+ + +G + + Y+L E ++M K A+ + A+ + N
Sbjct: 1175 KKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY-KLAITDLTTAISMDKN-- 1231
Query: 341 ASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGL--LVLKSLAYRN 398
S + Y R LC E + L+DY + + DA L + + L Y
Sbjct: 1232 -SYTAFYNRALCYTKIRELQMALTDYG--------IVLLLDATETVKLNTFLNRGLIYVE 1282
Query: 399 KGSFDEAAK-IMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYH 457
G + A + + L S + + HA A+ H ++ +A F AL+ + + +
Sbjct: 1283 LGQYGFALEDFKQAALISRTNGSLCHAT-AMCHHRINEFEEAVNFFTWALKINPCFLDAY 1341
Query: 458 YQLGLTYWFMGEETRKDKTK-ALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGC 516
G +Y G + + TK A FLKA ++ K G+ + A+G
Sbjct: 1342 VGRGNSYMEYGHD---EATKQAQKDFLKALHINPAYIKARISFGYNLQ--------AQGK 1390
Query: 517 YRKAFE----LDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGL 572
++KA+ DTD ++ A +V M A + + T RG+
Sbjct: 1391 FQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGV 1450
Query: 573 YYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESI 632
+ G A+ D Q A+ +PK + + G Y ++ A F+KA + +PE+
Sbjct: 1451 IHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENE 1510
Query: 633 YSVFKVAAIQQILGKYKEAVAQYQMIIK 660
Y + A IL KY+EA + +I+
Sbjct: 1511 YVLMNRAITNTILKKYEEAKEDFANVIE 1538
Score = 38.5 bits (88), Expect = 0.051
Identities = 100/521 (19%), Positives = 187/521 (35%), Gaps = 82/521 (15%)
Query: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
+A+ RRG Y K G+ A+ DLQ + +P N + YL + AL
Sbjct: 918 FAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYI 977
Query: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAAL 684
+ N + + A I + A+ Y IK GE + + K
Sbjct: 978 HKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLA 1037
Query: 685 VD------YLDGKAVDYIEK-------------ALEYFTCAL-------QHRADVSCLWK 718
+D + D K D + K A+E FT L Q R + K
Sbjct: 1038 IDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMK 1097
Query: 719 LAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNT 778
A +Y +A + L + + L++ + +A++++
Sbjct: 1098 YYDLAKFTIYQIAEMDKGLSELSPM-----------QQALIYSFCENHDKAIEVLD---- 1142
Query: 779 WCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVA--- 835
GI++ R + + + + ++++ LKKA+ S++ +A + A
Sbjct: 1143 ----GISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCL 1198
Query: 836 -----CYSGIGN----YALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKM 886
CY GN Y LA +I ++ + A+ N + Y ++ A + +
Sbjct: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGI 1258
Query: 887 AQSLDPS---YLMCWIGQALIAEAVGSYD-TMDLFRHTTELNMHTEGALGYAYWVCTTLQ 942
LD + L ++ + LI +G Y ++ F+ L T G+L +A +C
Sbjct: 1259 VLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRI 1317
Query: 943 DKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANA 1002
++ + + A+ L+ YV R +Y H + K+A
Sbjct: 1318 NEFEEAVNFFTW------ALKINPCFLDAYVGRGNSYME--------YGHDEATKQAQKD 1363
Query: 1003 YQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAF 1043
+ +A+ + Y A ++G L + G++ KA F
Sbjct: 1364 FLKALHI------NPAYIKARISFGYNLQAQGKFQKAWNHF 1398
Score = 34.7 bits (78), Expect = 0.74
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 3/137 (2%)
Query: 544 MEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKD---FNC 600
M LAI T + + A+ R L Y K + A+ D L D + N
Sbjct: 1213 MTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNT 1272
Query: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
+ + G Y+ G Y AL+ F +A+ ++ + A + +++EAV + +K
Sbjct: 1273 FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
Query: 661 KKEDYVPALKGLGECHL 677
++ A G G ++
Sbjct: 1333 INPCFLDAYVGRGNSYM 1349
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 55.1 bits (131), Expect = 5e-07
Identities = 89/388 (22%), Positives = 155/388 (39%), Gaps = 37/388 (9%)
Query: 286 KKYEDAVRNLTEGLKESPVCTSGWYHLA-----EAQVKMHRPKEAVLSCSQALKIVDNLG 340
KK DA+ + +G + + Y+L E ++M K A+ + A+ + N
Sbjct: 1175 KKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTY-KLAITDLTTAISMDKN-- 1231
Query: 341 ASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGL--LVLKSLAYRN 398
S + Y R LC E + L+DY + + DA L + + L Y
Sbjct: 1232 -SYIAFYNRALCYTKIRELQMALTDYG--------IVLLLDATETVKLNTFLNRGLIYVE 1282
Query: 399 KGSFDEAAK-IMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYH 457
G + A + + L S + + HA A+ H ++ +A F AL+ + + +
Sbjct: 1283 LGQYGFALEDFKQAALISRTNGSLCHAT-AMCHHRINEFEEAVNFFTWALKINPCFLDAY 1341
Query: 458 YQLGLTYWFMGEETRKDKTK-ALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGC 516
G +Y G + + TK A FLKA ++ K G+ + A+G
Sbjct: 1342 VGRGNSYMEYGHD---EATKQAQKDFLKALHINPAYIKARISFGYNLQ--------AQGK 1390
Query: 517 YRKAFE----LDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGL 572
++KA+ DTD ++ A +V M A + + T RG+
Sbjct: 1391 FQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGV 1450
Query: 573 YYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESI 632
+ G A+ D Q A+ +PK + + G Y ++ A F+KA + +PE+
Sbjct: 1451 IHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENE 1510
Query: 633 YSVFKVAAIQQILGKYKEAVAQYQMIIK 660
Y + A IL KY+EA + +I+
Sbjct: 1511 YVLMNRAITNTILKKYEEAKEDFANVIE 1538
Score = 39.7 bits (91), Expect = 0.023
Identities = 100/521 (19%), Positives = 188/521 (36%), Gaps = 82/521 (15%)
Query: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
+A+ RRG Y K G+ A+ DLQ + +P N + YL + AL
Sbjct: 918 FAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYI 977
Query: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAAL 684
+ N + + A I + A+ Y IK GE + + K
Sbjct: 978 HKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLA 1037
Query: 685 VD------YLDGKAVDYIEK-------------ALEYFTCAL-------QHRADVSCLWK 718
+D + D K D + K A+E FT L Q R + K
Sbjct: 1038 IDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMK 1097
Query: 719 LAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNT 778
A +Y +A + L + + L++ + +A++++
Sbjct: 1098 YYDLAKFTIYQIAEMDKGLSELSPM-----------QQALIYSFCENHDKAIEVLD---- 1142
Query: 779 WCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVA--- 835
GI++ R + + + + ++++ LKKA+ S++ +A + A
Sbjct: 1143 ----GISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCL 1198
Query: 836 -----CYSGIGN----YALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKM 886
CY GN Y LA +I ++ + +A+ N + Y ++ A + +
Sbjct: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGI 1258
Query: 887 AQSLDPS---YLMCWIGQALIAEAVGSYD-TMDLFRHTTELNMHTEGALGYAYWVCTTLQ 942
LD + L ++ + LI +G Y ++ F+ L T G+L +A +C
Sbjct: 1259 VLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRI 1317
Query: 943 DKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANA 1002
++ + + A+ L+ YV R +Y H + K+A
Sbjct: 1318 NEFEEAVNFFTW------ALKINPCFLDAYVGRGNSYME--------YGHDEATKQAQKD 1363
Query: 1003 YQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAF 1043
+ +A+ + Y A ++G L + G++ KA F
Sbjct: 1364 FLKALHI------NPAYIKARISFGYNLQAQGKFQKAWNHF 1398
Score = 34.3 bits (77), Expect = 0.97
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 3/137 (2%)
Query: 544 MEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKD---FNC 600
M LAI T + + A+ R L Y K + A+ D L D + N
Sbjct: 1213 MTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNT 1272
Query: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
+ + G Y+ G Y AL+ F +A+ ++ + A + +++EAV + +K
Sbjct: 1273 FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
Query: 661 KKEDYVPALKGLGECHL 677
++ A G G ++
Sbjct: 1333 INPCFLDAYVGRGNSYM 1349
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 54.7 bits (130), Expect = 7e-07
Identities = 91/404 (22%), Positives = 161/404 (39%), Gaps = 33/404 (8%)
Query: 265 VEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKE 324
V+M +K + + KAL + D + T + + G ++ E ++M K
Sbjct: 1160 VQMKAKRTKEAVEVLKKALDASSHSDKGPDATT-ISADCLYNLGLCYMEEGNLQMTY-KL 1217
Query: 325 AVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADN 384
A+ + A+ + N S + Y R LC E + L+DY + + DA
Sbjct: 1218 AITDLTTAISMDKN---SYIAFYNRALCYTKIRELQMALTDYG--------IVLLLDATE 1266
Query: 385 IPGL--LVLKSLAYRNKGSFDEAAK-IMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEK 441
L + + L Y G + A + + L S + + HA A+ H ++ +A
Sbjct: 1267 TVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHAT-AMCHHRINEFEEAVN 1325
Query: 442 CFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTK-ALTHFLKAARLDTYMGKVFCYLG 500
F AL+ + + + G +Y G + + TK A FLKA ++ K G
Sbjct: 1326 FFTWALKINPCFLDAYVGRGNSYMEYGHD---EATKQAQKDFLKALHINPAYIKARISFG 1382
Query: 501 HYYRDVVGDKNRARGCYRKAFE----LDDTDAESGAAAVDLSVELEDMEMALAILTTVTQ 556
+ + A+G ++KA+ DTD ++ A +V M A + +
Sbjct: 1383 YNLQ--------AQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINA 1434
Query: 557 KASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTT 616
T RG+ + G A+ D Q A+ +PK + + G Y ++
Sbjct: 1435 AMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQ 1494
Query: 617 ALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
A F+KA + +PE+ Y + A IL KY+EA + +I+
Sbjct: 1495 ASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIE 1538
Score = 40.0 bits (92), Expect = 0.018
Identities = 100/521 (19%), Positives = 188/521 (36%), Gaps = 82/521 (15%)
Query: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
+A+ RRG Y K G+ A+ DLQ + +P N + YL + AL
Sbjct: 918 FAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYI 977
Query: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAAL 684
+ N + + A I + A+ Y IK GE + + K
Sbjct: 978 HKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLA 1037
Query: 685 VD------YLDGKAVDYIEK-------------ALEYFTCAL-------QHRADVSCLWK 718
+D + D K D + K A+E FT L Q R + K
Sbjct: 1038 IDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMK 1097
Query: 719 LAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNT 778
A +Y +A + L + + L++ + +A++++
Sbjct: 1098 YYDLAKFTIYQIAEMDKGLSELSPM-----------QQALIYSFCENHDKAIEVLD---- 1142
Query: 779 WCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVA--- 835
GI++ R + + + + ++++ LKKA+ S++ +A + A
Sbjct: 1143 ----GISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDASSHSDKGPDATTISADCL 1198
Query: 836 -----CYSGIGN----YALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKM 886
CY GN Y LA +I ++ + +A+ N + Y ++ A + +
Sbjct: 1199 YNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGI 1258
Query: 887 AQSLDPS---YLMCWIGQALIAEAVGSYD-TMDLFRHTTELNMHTEGALGYAYWVCTTLQ 942
LD + L ++ + LI +G Y ++ F+ L T G+L +A +C
Sbjct: 1259 VLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA-LISRTNGSLCHATAMCHHRI 1317
Query: 943 DKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANA 1002
++ + + A+ L+ YV R +Y H + K+A
Sbjct: 1318 NEFEEAVNFFTW------ALKINPCFLDAYVGRGNSYME--------YGHDEATKQAQKD 1363
Query: 1003 YQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAF 1043
+ +A+ + Y A ++G L + G++ KA F
Sbjct: 1364 FLKALHI------NPAYIKARISFGYNLQAQGKFQKAWNHF 1398
Score = 34.3 bits (77), Expect = 0.97
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 3/137 (2%)
Query: 544 MEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKD---FNC 600
M LAI T + + A+ R L Y K + A+ D L D + N
Sbjct: 1213 MTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNT 1272
Query: 601 WESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIK 660
+ + G Y+ G Y AL+ F +A+ ++ + A + +++EAV + +K
Sbjct: 1273 FLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALK 1332
Query: 661 KKEDYVPALKGLGECHL 677
++ A G G ++
Sbjct: 1333 INPCFLDAYVGRGNSYM 1349
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 52.0 bits (123), Expect = 4e-06
Identities = 73/325 (22%), Positives = 128/325 (39%), Gaps = 59/325 (18%)
Query: 356 KAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSS 415
KA ++ DY+ + E ++ L++ L +L Y K F +A SS
Sbjct: 430 KAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGK-DFAQA--------SS 480
Query: 416 YPDLA---EVHALEALIH-----FTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFM 467
Y D+A + + AL + F DY +A + ++ AL D+ E Y +GLTY
Sbjct: 481 YADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTY--- 537
Query: 468 GEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTD 527
E +AL FLK + +V + + Y EL +
Sbjct: 538 --EKLNRLDEALDCFLKLHAILRNSAEVLYQIANIY------------------ELMENP 577
Query: 528 AESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADL 587
+++ +E + ++++ T Q S + G Y + G SQA
Sbjct: 578 SQA----------IEWLMQVVSVIPTDPQVLS---------KLGELYDREGDKSQAFQYY 618
Query: 588 QAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGK 647
+ R P + E LG Y+ + A++ F +AS + P + VA+ + G
Sbjct: 619 YESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGN 678
Query: 648 YKEAVAQYQMIIKKKEDYVPALKGL 672
Y++A+ Y+ +K + V L+ L
Sbjct: 679 YQKALDTYKDTHRKFPENVECLRFL 703
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 52.0 bits (123), Expect = 4e-06
Identities = 73/325 (22%), Positives = 128/325 (39%), Gaps = 59/325 (18%)
Query: 356 KAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSS 415
KA ++ DY+ + E ++ L++ L +L Y K F +A SS
Sbjct: 421 KAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGK-DFAQA--------SS 471
Query: 416 YPDLA---EVHALEALIH-----FTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFM 467
Y D+A + + AL + F DY +A + ++ AL D+ E Y +GLTY
Sbjct: 472 YADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTY--- 528
Query: 468 GEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTD 527
E +AL FLK + +V + + Y EL +
Sbjct: 529 --EKLNRLDEALDCFLKLHAILRNSAEVLYQIANIY------------------ELMENP 568
Query: 528 AESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADL 587
+++ +E + ++++ T Q S + G Y + G SQA
Sbjct: 569 SQA----------IEWLMQVVSVIPTDPQVLS---------KLGELYDREGDKSQAFQYY 609
Query: 588 QAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGK 647
+ R P + E LG Y+ + A++ F +AS + P + VA+ + G
Sbjct: 610 YESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGN 669
Query: 648 YKEAVAQYQMIIKKKEDYVPALKGL 672
Y++A+ Y+ +K + V L+ L
Sbjct: 670 YQKALDTYKDTHRKFPENVECLRFL 694
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 51.2 bits (121), Expect = 8e-06
Identities = 74/323 (22%), Positives = 126/323 (39%), Gaps = 49/323 (15%)
Query: 591 LRADPK---DFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGK 647
L+A+ K DF C LG L Y AL ++ + L + +K AA LG
Sbjct: 85 LKAEGKVESDFFC--QLGHFNLLLEDYPKALSAYQRYYSLQSD----YWKNAAFLYGLGL 138
Query: 648 YKEAVAQYQMIIKKKEDYV---PALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT 704
+Q IK ++ + P+ E HL + V+ DY E +L++F
Sbjct: 139 VYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN------TDY-ESSLKHFQ 191
Query: 705 CALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGR 764
AL V C + CT ++ +++ H+ + Q++ + E
Sbjct: 192 LAL-----VDC------NPCT----LSNAEIQFHIAHLYETQRKYHSAKEAYE------- 229
Query: 765 CYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNN 824
+L+ T N + +Q + T + D ++ L+K++ D N+
Sbjct: 230 ------QLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNS 283
Query: 825 HLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAF 884
W LG CYS IG A + +SI + +A W ++GVLY A +A+
Sbjct: 284 GQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY 341
Query: 885 KMAQSLDPSYLMCWIGQALIAEA 907
A LD + W+ + E+
Sbjct: 342 ICAVQLDHGHAAAWMDLGTLYES 364
Score = 35.4 bits (80), Expect = 0.44
Identities = 18/48 (37%), Positives = 22/48 (45%)
Query: 41 NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88
+ W IGV + QP A AY A +L+ AW L LYE N
Sbjct: 319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 366
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 51.2 bits (121), Expect = 8e-06
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 17/144 (11%)
Query: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
+A+ G ++ + +A+A + A+R +P+ +N W LG Y + ++ A F KA
Sbjct: 608 YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 667
Query: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQ-----------------MIIKKKEDYVP 667
++NP+S + + +Q L K ++A+ ++ E Y
Sbjct: 668 LDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKS 727
Query: 668 ALKGLGECHLMMAKAALVDYLDGK 691
AL+ L E ++ K +LV +L GK
Sbjct: 728 ALQELEELKQIVPKESLVYFLIGK 751
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 803 LKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAV 862
L E L+K+L C + A+R++ ++ W LG++ Y ++LA+ F K++ ++V
Sbjct: 619 LTEELDKALACFRNAIRVNPRHYNAWYGLGMI--YYKQEKFSLAEMHFQKALDINPQSSV 676
Query: 863 AWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSY 911
++GV+ + E+A + A +DP +C +A + A Y
Sbjct: 677 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKY 725
Score = 40.0 bits (92), Expect = 0.018
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 18/163 (11%)
Query: 756 NELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLK----ELLEKSL 811
N L HL Y L + +L + Y QA+ + + + + E+ +L
Sbjct: 492 NILSHLPSHHYNTGWVLCQIGRAYFEL--SEYMQAERIFSEVRRIENYRVEGMEIYSTTL 549
Query: 812 HCLKKAVRL----------DSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINA 861
L+K V L D N+ W A G C+S + +A F ++IQ + A
Sbjct: 550 WHLQKDVALSVLSKDLTDMDKNSPEAWCAAG--NCFSLQREHDIAIKFFQRAIQVDPNYA 607
Query: 862 VAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALI 904
A+T LG ++ E +++A F+ A ++P + W G +I
Sbjct: 608 YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMI 650
Score = 39.7 bits (91), Expect = 0.023
Identities = 104/543 (19%), Positives = 201/543 (37%), Gaps = 82/543 (15%)
Query: 161 RKLTQFLAE--STEDQNNETQQLL---FTAFENALGL-SDKIPSEDHQVLYRHFIQSLSK 214
R++T LA+ S+ Q + T Q+L T+ NAL S ++ + D + + K
Sbjct: 346 REVTPILAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMK 405
Query: 215 FPHESARLK---KACEGMINIYPTVQYPLEVLCLH--LIESGNLTDEGQQYCCRLVEMDS 269
FP + K K +G I P + LE+ L +I G ++ Q + +
Sbjct: 406 FPPKIPNRKTKSKTNKGGIT-QPNINDSLEITKLDSSIISEGKISTITPQI--QAFNLQK 462
Query: 270 KSGPGLIGL------GIKALQDKKYEDAVRNLTEGLKESPVCTSGWY--HLAEAQVKMHR 321
+ GL+ L G AL ++A+ L+ S +GW + A ++
Sbjct: 463 AAAEGLMSLLREMGKGYLALCSYNCKEAINILSH--LPSHHYNTGWVLCQIGRAYFELSE 520
Query: 322 PKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISD 381
+A S+ +I +N G +Y L HL+ + + + D ++D
Sbjct: 521 YMQAERIFSEVRRI-ENYRVEGMEIYSTTLW-HLQKDVALSVLSKD-----------LTD 567
Query: 382 AD-NIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAE 440
D N P + + D A K + + P+ A + L ++ +A
Sbjct: 568 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 627
Query: 441 KCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDK-TKALTHFLKAARLDTYMGKVFCYL 499
CF+ A+ + Y LG+ Y+ +++K + A HF KA ++ + C++
Sbjct: 628 ACFRNAIRVNPRHYNAWYGLGMIYY------KQEKFSLAEMHFQKALDINPQSSVLLCHI 681
Query: 500 GHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKAS 559
G + + +A KA +D +
Sbjct: 682 G-VVQHALKKSEKALDTLNKAIVIDPKNP------------------------------- 709
Query: 560 AGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALK 619
R ++ A+ +L+ + PK+ + +G+ Y G AL
Sbjct: 710 -----LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 764
Query: 620 SFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMM 679
+F+ A +L+P+ + K A ++ L +E + Q + I+ E ++ + L
Sbjct: 765 NFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHA 824
Query: 680 AKA 682
A++
Sbjct: 825 AES 827
Score = 38.1 bits (87), Expect = 0.067
Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 21/146 (14%)
Query: 774 STSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGV 833
++ WC G + Q +H + ++ ++A+++D N + LG
Sbjct: 571 NSPEAWCAAGNCFSLQREH---------------DIAIKFFQRAIQVDPNYAYAYTLLGH 615
Query: 834 VACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDP- 892
+ + ALA CF +I+ + AW LG++Y E A F+ A ++P
Sbjct: 616 EFVLTEELDKALA--CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 673
Query: 893 -SYLMCWIG--QALIAEAVGSYDTMD 915
S L+C IG Q + ++ + DT++
Sbjct: 674 SSVLLCHIGVVQHALKKSEKALDTLN 699
Score = 35.4 bits (80), Expect = 0.44
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 20 KEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQG 79
+E+ A+K + ++ + N A+ +G E+ D+A + ++ A + P AW G
Sbjct: 587 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 646
Query: 80 LANLYEKYNHINAKDDLPGVYQKLLDL 106
L +Y K + + +QK LD+
Sbjct: 647 LGMIYYKQEKFSLAE---MHFQKALDI 670
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 51.2 bits (121), Expect = 8e-06
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 17/144 (11%)
Query: 565 WAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKA 624
+A+ G ++ + +A+A + A+R +P+ +N W LG Y + ++ A F KA
Sbjct: 602 YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 661
Query: 625 SELNPESIYSVFKVAAIQQILGKYKEAVAQYQ-----------------MIIKKKEDYVP 667
++NP+S + + +Q L K ++A+ ++ E Y
Sbjct: 662 LDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKS 721
Query: 668 ALKGLGECHLMMAKAALVDYLDGK 691
AL+ L E ++ K +LV +L GK
Sbjct: 722 ALQELEELKQIVPKESLVYFLIGK 745
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 803 LKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAV 862
L E L+K+L C + A+R++ ++ W LG++ Y ++LA+ F K++ ++V
Sbjct: 613 LTEELDKALACFRNAIRVNPRHYNAWYGLGMI--YYKQEKFSLAEMHFQKALDINPQSSV 670
Query: 863 AWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSY 911
++GV+ + E+A + A +DP +C +A + A Y
Sbjct: 671 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKY 719
Score = 40.0 bits (92), Expect = 0.018
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 18/163 (11%)
Query: 756 NELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLK----ELLEKSL 811
N L HL Y L + +L + Y QA+ + + + + E+ +L
Sbjct: 486 NILSHLPSHHYNTGWVLCQIGRAYFEL--SEYMQAERIFSEVRRIENYRVEGMEIYSTTL 543
Query: 812 HCLKKAVRL----------DSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINA 861
L+K V L D N+ W A G C+S + +A F ++IQ + A
Sbjct: 544 WHLQKDVALSVLSKDLTDMDKNSPEAWCAAG--NCFSLQREHDIAIKFFQRAIQVDPNYA 601
Query: 862 VAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALI 904
A+T LG ++ E +++A F+ A ++P + W G +I
Sbjct: 602 YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMI 644
Score = 39.7 bits (91), Expect = 0.023
Identities = 104/543 (19%), Positives = 201/543 (37%), Gaps = 82/543 (15%)
Query: 161 RKLTQFLAE--STEDQNNETQQLL---FTAFENALGL-SDKIPSEDHQVLYRHFIQSLSK 214
R++T LA+ S+ Q + T Q+L T+ NAL S ++ + D + + K
Sbjct: 340 REVTPILAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMK 399
Query: 215 FPHESARLK---KACEGMINIYPTVQYPLEVLCLH--LIESGNLTDEGQQYCCRLVEMDS 269
FP + K K +G I P + LE+ L +I G ++ Q + +
Sbjct: 400 FPPKIPNRKTKSKTNKGGIT-QPNINDSLEITKLDSSIISEGKISTITPQI--QAFNLQK 456
Query: 270 KSGPGLIGL------GIKALQDKKYEDAVRNLTEGLKESPVCTSGWY--HLAEAQVKMHR 321
+ GL+ L G AL ++A+ L+ S +GW + A ++
Sbjct: 457 AAAEGLMSLLREMGKGYLALCSYNCKEAINILSH--LPSHHYNTGWVLCQIGRAYFELSE 514
Query: 322 PKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISD 381
+A S+ +I +N G +Y L HL+ + + + D ++D
Sbjct: 515 YMQAERIFSEVRRI-ENYRVEGMEIYSTTLW-HLQKDVALSVLSKD-----------LTD 561
Query: 382 AD-NIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAE 440
D N P + + D A K + + P+ A + L ++ +A
Sbjct: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621
Query: 441 KCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDK-TKALTHFLKAARLDTYMGKVFCYL 499
CF+ A+ + Y LG+ Y+ +++K + A HF KA ++ + C++
Sbjct: 622 ACFRNAIRVNPRHYNAWYGLGMIYY------KQEKFSLAEMHFQKALDINPQSSVLLCHI 675
Query: 500 GHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKAS 559
G + + +A KA +D +
Sbjct: 676 G-VVQHALKKSEKALDTLNKAIVIDPKNP------------------------------- 703
Query: 560 AGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALK 619
R ++ A+ +L+ + PK+ + +G+ Y G AL
Sbjct: 704 -----LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 758
Query: 620 SFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMM 679
+F+ A +L+P+ + K A ++ L +E + Q + I+ E ++ + L
Sbjct: 759 NFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHA 818
Query: 680 AKA 682
A++
Sbjct: 819 AES 821
Score = 38.1 bits (87), Expect = 0.067
Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 21/146 (14%)
Query: 774 STSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGV 833
++ WC G + Q +H + ++ ++A+++D N + LG
Sbjct: 565 NSPEAWCAAGNCFSLQREH---------------DIAIKFFQRAIQVDPNYAYAYTLLGH 609
Query: 834 VACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDP- 892
+ + ALA CF +I+ + AW LG++Y E A F+ A ++P
Sbjct: 610 EFVLTEELDKALA--CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Query: 893 -SYLMCWIG--QALIAEAVGSYDTMD 915
S L+C IG Q + ++ + DT++
Sbjct: 668 SSVLLCHIGVVQHALKKSEKALDTLN 693
Score = 35.4 bits (80), Expect = 0.44
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 20 KEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQG 79
+E+ A+K + ++ + N A+ +G E+ D+A + ++ A + P AW G
Sbjct: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
Query: 80 LANLYEKYNHINAKDDLPGVYQKLLDL 106
L +Y K + + +QK LD+
Sbjct: 641 LGMIYYKQEKFSLAE---MHFQKALDI 664
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 47.4 bits (111), Expect = 1e-04
Identities = 156/752 (20%), Positives = 272/752 (36%), Gaps = 131/752 (17%)
Query: 395 AYRNKGSFDEAAKIMEDLLSSYPDLAE----VHALEALIHFTK--------KDYLQAEKC 442
AY + +FD+A +L +L E + A L H + K Y + +
Sbjct: 403 AYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLG 462
Query: 443 FQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTY--MGKVFCYLG 500
L+ LG+ + G+ K TH A L Y G+ + +G
Sbjct: 463 IAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHK-THLCIAQELSDYAAQGRAYGNMG 521
Query: 501 HYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASA 560
+ Y A G Y +A + +++++++ + +Q ++
Sbjct: 522 NAYN--------ALGMYDQA----------------VKYHRQELQISMEVNDRASQASTH 557
Query: 561 GTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKS 620
G A+ G + +A QH Q ++ LR + +LG + SRG Y A
Sbjct: 558 GNLAVAYQALGAHD-RALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPY 616
Query: 621 FTKASELNPE--SIYSVFKVAA----IQQILGKYKEAVAQYQMIIKKKEDYVPAL-KGLG 673
+ + L P+ + KV LG Y+EAV Y+ + +D L +
Sbjct: 617 YEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKA 676
Query: 674 ECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPS 733
C+L +A AL+++ KA + + L +A L L GD C
Sbjct: 677 YCNLGLAFKALLNF--SKAEECQKYLLSLAQSLNNSQAKFRALGNL-GDIFIC------- 726
Query: 734 KVNVHVLGVLLGQKEGKQVLKKNEL-LHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQH 792
+K+ +K E L L + R L+ ++ + LG Y ++
Sbjct: 727 ------------KKDINGAIKFYEQQLGLAHQVKDRRLE----ASAYAALGTAYRMIQKY 770
Query: 793 LAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIK 852
G + +L+ E L L R ++ HL A Y +G Y +A C+ +
Sbjct: 771 DKALGYHTQELEVYQE--LSDLPGECR--AHGHL-------AAVYMALGKYTMAFKCYEE 819
Query: 853 SIQSEQ------INAVAWTNLGVLYLTNENIEQAHEAFK----MAQSLDPSYLMCWIGQA 902
+ Q + A + N+G+ + +E+A F+ M Q L + + G+A
Sbjct: 820 QLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRA 879
Query: 903 L-----IAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNIL 957
EA+G Y E A+ Y + Q + + + Y L
Sbjct: 880 YGNLGDCYEALGDY----------------EEAIKYYEQYLSVAQSLNRMQDQAKAYRGL 923
Query: 958 -----QMNAIPAAQVILNKYVERIQ------NYAPAFTMLGYLNEHLQLKKEAANAYQRA 1006
M ++ A V K + N A A+ LG L+ L ++A + +R
Sbjct: 924 GNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQ 983
Query: 1007 ILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIG---FALALFM 1063
+ + + +D+ + A G + GEYD A+Q + L++ E+ A
Sbjct: 984 LNIARDMKDRALESDAACGLGGVYQQMGEYDTALQ-YHQLDLQIAEETNNPTCQGRAYGN 1042
Query: 1064 KGLYKESSKAYERALSIVESEQDKAHILTALA 1095
GL ES +ERA+ E A + LA
Sbjct: 1043 LGLTYESLGTFERAVVYQEQHLSIAAQMNDLA 1074
Score = 47.0 bits (110), Expect = 1e-04
Identities = 115/568 (20%), Positives = 202/568 (35%), Gaps = 145/568 (25%)
Query: 578 GQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFK 637
G A+ AL DP++ + + AY+ Y AL KA LNP+ + F+
Sbjct: 72 GDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFR 131
Query: 638 VAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLD-------- 689
Q LG++ +A+A + + + + L G+ E + K+ + D L+
Sbjct: 132 QGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAM---KSPMRDSLEPTYQQLQK 188
Query: 690 ------------------------GKAVDYIEKALEYFTCALQHRADV-----SCLWKLA 720
G +V +E AL+ TC+L+ R V S W L
Sbjct: 189 MKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLG 248
Query: 721 GDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWC 780
+ Y V LG + G+ R +G
Sbjct: 249 NTEKSTGYMQQDLDV-----AKTLGDQTGE------------CRAHG------------- 278
Query: 781 DLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGI 840
+LG ++ + + +E L H L A++L + Y+ I
Sbjct: 279 NLGSAFFSKGNY-----------REALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAI 327
Query: 841 GNY--ALAQH--CFIKSIQS--EQINAVAWTNLGVLYLTN---ENIEQAHEA-FKMAQSL 890
G+Y ALA H C + + QS E A N+G +Y+ EN Q HE K+A+
Sbjct: 328 GDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAK-- 385
Query: 891 DPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETE 950
DL E ++ Y Y + N +
Sbjct: 386 ------------------------DLGNKREEARAYSNLGSAYHY--------RRNFDKA 413
Query: 951 LYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLL 1010
+ +N + + AQ ++ K +E A+ LG+ +Q + A +++ + +
Sbjct: 414 MSYHNYV----LELAQELMEKAIE-----MRAYAGLGHAARCMQDLERAKQYHEQQLGIA 464
Query: 1011 QTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFAL----------A 1060
+ +D+ A N G + G+YD A++ K T L + +++ +A A
Sbjct: 465 EDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHK-THLCIAQELSDYAAQGRAYGNMGNA 523
Query: 1061 LFMKGLYKESSKAYERALSIVESEQDKA 1088
G+Y ++ K + + L I D+A
Sbjct: 524 YNALGMYDQAVKYHRQELQISMEVNDRA 551
Score = 37.4 bits (85), Expect = 0.11
Identities = 125/610 (20%), Positives = 222/610 (36%), Gaps = 77/610 (12%)
Query: 542 EDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCW 601
+D+++A + + + G A+ +G Y H + L L+ +
Sbjct: 259 QDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLV-LAMKLKDREAASSAL 317
Query: 602 ESLGEAYLSRGGYTTALKS------FTKASELNPESIYSVFKVAAIQQILGKYKEAVAQY 655
SLG Y + G Y AL S K S+ + + A+ +G ++ AV +
Sbjct: 318 SSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCH 377
Query: 656 QMIIK------KKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDY----IEKALEYFTC 705
+ +K K + A LG + KA+ Y +E A E
Sbjct: 378 EQHLKIAKDLGNKREEARAYSNLGSAYHYRRNF-------DKAMSYHNYVLELAQELMEK 430
Query: 706 ALQHRADVSCLWKLAGDACTCLYAVAPSK-VNVHVLGVLLGQKEGKQVLKKNE---LLHL 761
A++ RA + G A C+ + +K + LG+ K+ + + ++H
Sbjct: 431 AIEMRA-----YAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQ 485
Query: 762 GGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDL----------KELLEKSL 811
Y ALKL T +Y Q + G+ N L ++ L+ S+
Sbjct: 486 MKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISM 545
Query: 812 HCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALA-QHC-----FIKSIQSEQINAVAWT 865
+A + ++ +L Y +G + A QH + ++ Q A A +
Sbjct: 546 EVNDRASQASTHGNL-------AVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALS 598
Query: 866 NLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNM 925
NLG + + QA ++ L P L G+ + +G Y L + E
Sbjct: 599 NLGNFHCSRGEYVQAAPYYEQYLRLAPD-LQDMEGEGKVCHNLG-YAHYCLGNY-QEAVK 655
Query: 926 HTEGALGYAYWVCTTL-QDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFT 984
+ E L A + L Q K+ L +L + Q L + + N F
Sbjct: 656 YYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFR 715
Query: 985 MLGYLNEHLQLKKE---AANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQ 1041
LG L + KK+ A Y++ + L +D+ A G +YDKA+
Sbjct: 716 ALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKAL- 774
Query: 1042 AFKSTPLEVLEDII---------GFALALFMK-GLYKESSKAYERALSIVESEQD---KA 1088
+ + LEV +++ G A++M G Y + K YE L + + +D +A
Sbjct: 775 GYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEA 834
Query: 1089 HILTALAITE 1098
+ + IT+
Sbjct: 835 QVYGNMGITK 844
Score = 34.7 bits (78), Expect = 0.74
Identities = 43/180 (23%), Positives = 69/180 (38%), Gaps = 27/180 (15%)
Query: 978 NYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYD 1037
N A A+ LG + LQ YQ + + + D + A+ N G CS GEY
Sbjct: 559 NLAVAYQALGAHDRALQ-------HYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYV 611
Query: 1038 KAIQAFKS--TPLEVLEDIIG-------FALALFMKGLYKESSKAYERALSIVESEQDKA 1088
+A ++ L+D+ G A + G Y+E+ K YE+ L++ + DK
Sbjct: 612 QAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDK- 670
Query: 1089 HILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATLSKAALNEL 1148
Q K L FK + E + L +L ++ ++ AL L
Sbjct: 671 ----------LSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNL 720
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/110 (27%), Positives = 52/110 (47%)
Query: 574 YLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIY 633
Y KA + A+ A+ +P + + + AYL Y AL T+A EL+ + I
Sbjct: 38 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97
Query: 634 SVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAA 683
++ AA LGK++ A+ Y+ ++K K A EC+ ++ + A
Sbjct: 98 GYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKA 147
>gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]
Length = 626
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/85 (28%), Positives = 46/85 (54%)
Query: 571 GLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPE 630
G+ + +G+ ++A+ AAL P+D++ W LG + A++++T+A E+ P
Sbjct: 481 GVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPG 540
Query: 631 SIYSVFKVAAIQQILGKYKEAVAQY 655
I S + + LG Y+EAV+ +
Sbjct: 541 FIRSRYNLGISCINLGAYREAVSNF 565
Score = 39.3 bits (90), Expect = 0.030
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 571 GLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPE 630
GL LK G + ++AA+ DP D W+ LG A+ + + EL P
Sbjct: 333 GLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPN 392
Query: 631 SIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDY---VPALKGLGECHLMMAKAAL-VD 686
++ ++ +A G ++A + IK+ Y V + KG M+K+ +
Sbjct: 393 NLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSS 452
Query: 687 YLDGKAVDYIEKA 699
L+G Y+E A
Sbjct: 453 VLEGVKELYLEAA 465
Score = 37.7 bits (86), Expect = 0.088
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 30 KTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYNH 89
+ + Q+ + AW F+G+ AE E A A ++ EL+P+ L A LA Y H
Sbjct: 350 EAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGH 409
>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
sapiens]
Length = 864
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/200 (22%), Positives = 88/200 (44%), Gaps = 15/200 (7%)
Query: 764 RCYGRALKLMSTSNTWCDLGINYYRQAQH---LAETGSNMNDLKELLEKSLHCLKKAVRL 820
+CY + K +C + ++ + A+H LA G +N L + E++ ++K +R
Sbjct: 19 KCYEQ--KQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKK-EEAYEFVRKGLRN 75
Query: 821 DSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQA 880
D +H+ W+ G++ Y A C+ +++ ++ N +L +L + ++E
Sbjct: 76 DVKSHVCWHVYGLLQ--RSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGY 133
Query: 881 HEAFKMAQSLDPSYLMCWIGQALIAEAVGSYD----TMDLFRHTTELNMHTEGALGYAYW 936
E L P+ WIG A+ + YD ++ FR T ++ + Y Y
Sbjct: 134 RETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQV---PPNKIDYEYS 190
Query: 937 VCTTLQDKSNRETELYQYNI 956
Q++ RE +L Q ++
Sbjct: 191 ELILYQNQVMREADLLQESL 210
Score = 31.2 bits (69), Expect = 8.2
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 570 RGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNP 629
+GL G+ +A ++ LR D K CW G S Y A+K + A +L+
Sbjct: 52 KGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDK 111
Query: 630 ESIYSVFKVAAIQ---QILGKYKEAVAQYQMI 658
+++ + ++ +Q + L Y+E +YQ++
Sbjct: 112 DNLQILRDLSLLQIQMRDLEGYRE--TRYQLL 141
>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo
sapiens]
Length = 1347
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 810 SLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGV 869
++ L+K++ D N+ W LG CYS IG A + +SI + +A W ++GV
Sbjct: 266 AIQYLQKSLEADPNSGQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGV 323
Query: 870 LYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEA 907
LY A +A+ A LD + W+ + E+
Sbjct: 324 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 361
Score = 35.4 bits (80), Expect = 0.44
Identities = 18/48 (37%), Positives = 22/48 (45%)
Query: 41 NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88
+ W IGV + QP A AY A +L+ AW L LYE N
Sbjct: 316 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 363
Score = 31.2 bits (69), Expect = 8.2
Identities = 16/76 (21%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 15 DAIRNKEYKE--ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPD 72
D + +K KE A+++ + L+ + N+ +W F+G + + + A +Y+++ +
Sbjct: 254 DLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEA 313
Query: 73 QLLAWQGLANLYEKYN 88
W + LY++ N
Sbjct: 314 SADTWCSIGVLYQQQN 329
>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo
sapiens]
Length = 1079
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 810 SLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGV 869
++ L+K++ D N+ W LG CYS IG A + +SI + +A W ++GV
Sbjct: 266 AIQYLQKSLEADPNSGQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGV 323
Query: 870 LYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEA 907
LY A +A+ A LD + W+ + E+
Sbjct: 324 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 361
Score = 35.4 bits (80), Expect = 0.44
Identities = 18/48 (37%), Positives = 22/48 (45%)
Query: 41 NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88
+ W IGV + QP A AY A +L+ AW L LYE N
Sbjct: 316 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 363
Score = 31.2 bits (69), Expect = 8.2
Identities = 16/76 (21%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 15 DAIRNKEYKE--ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPD 72
D + +K KE A+++ + L+ + N+ +W F+G + + + A +Y+++ +
Sbjct: 254 DLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEA 313
Query: 73 QLLAWQGLANLYEKYN 88
W + LY++ N
Sbjct: 314 SADTWCSIGVLYQQQN 329
>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo
sapiens]
Length = 1240
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 810 SLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGV 869
++ L+K++ D N+ W LG CYS IG A + +SI + +A W ++GV
Sbjct: 266 AIQYLQKSLEADPNSGQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGV 323
Query: 870 LYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEA 907
LY A +A+ A LD + W+ + E+
Sbjct: 324 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 361
Score = 35.4 bits (80), Expect = 0.44
Identities = 18/48 (37%), Positives = 22/48 (45%)
Query: 41 NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88
+ W IGV + QP A AY A +L+ AW L LYE N
Sbjct: 316 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 363
Score = 31.2 bits (69), Expect = 8.2
Identities = 16/76 (21%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 15 DAIRNKEYKE--ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPD 72
D + +K KE A+++ + L+ + N+ +W F+G + + + A +Y+++ +
Sbjct: 254 DLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEA 313
Query: 73 QLLAWQGLANLYEKYN 88
W + LY++ N
Sbjct: 314 SADTWCSIGVLYQQQN 329
>gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo
sapiens]
Length = 429
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/200 (22%), Positives = 88/200 (44%), Gaps = 15/200 (7%)
Query: 764 RCYGRALKLMSTSNTWCDLGINYYRQAQH---LAETGSNMNDLKELLEKSLHCLKKAVRL 820
+CY + K +C + ++ + A+H LA G +N L + E++ ++K +R
Sbjct: 19 KCYEQ--KQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKK-EEAYEFVRKGLRN 75
Query: 821 DSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQA 880
D +H+ W+ G++ Y A C+ +++ ++ N +L +L + ++E
Sbjct: 76 DVKSHVCWHVYGLLQ--RSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGY 133
Query: 881 HEAFKMAQSLDPSYLMCWIGQALIAEAVGSYD----TMDLFRHTTELNMHTEGALGYAYW 936
E L P+ WIG A+ + YD ++ FR T ++ + Y Y
Sbjct: 134 RETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQV---PPNKIDYEYS 190
Query: 937 VCTTLQDKSNRETELYQYNI 956
Q++ RE +L Q ++
Sbjct: 191 ELILYQNQVMREADLLQESL 210
Score = 31.2 bits (69), Expect = 8.2
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 570 RGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNP 629
+GL G+ +A ++ LR D K CW G S Y A+K + A +L+
Sbjct: 52 KGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDK 111
Query: 630 ESIYSVFKVAAIQ---QILGKYKEAVAQYQMI 658
+++ + ++ +Q + L Y+E +YQ++
Sbjct: 112 DNLQILRDLSLLQIQMRDLEGYRE--TRYQLL 141
>gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo
sapiens]
Length = 311
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/200 (22%), Positives = 88/200 (44%), Gaps = 15/200 (7%)
Query: 764 RCYGRALKLMSTSNTWCDLGINYYRQAQH---LAETGSNMNDLKELLEKSLHCLKKAVRL 820
+CY + K +C + ++ + A+H LA G +N L + E++ ++K +R
Sbjct: 19 KCYEQ--KQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKK-EEAYEFVRKGLRN 75
Query: 821 DSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQA 880
D +H+ W+ G++ Y A C+ +++ ++ N +L +L + ++E
Sbjct: 76 DVKSHVCWHVYGLLQ--RSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGY 133
Query: 881 HEAFKMAQSLDPSYLMCWIGQALIAEAVGSYD----TMDLFRHTTELNMHTEGALGYAYW 936
E L P+ WIG A+ + YD ++ FR T ++ + Y Y
Sbjct: 134 RETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQV---PPNKIDYEYS 190
Query: 937 VCTTLQDKSNRETELYQYNI 956
Q++ RE +L Q ++
Sbjct: 191 ELILYQNQVMREADLLQESL 210
Score = 31.2 bits (69), Expect = 8.2
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 570 RGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNP 629
+GL G+ +A ++ LR D K CW G S Y A+K + A +L+
Sbjct: 52 KGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDK 111
Query: 630 ESIYSVFKVAAIQ---QILGKYKEAVAQYQMI 658
+++ + ++ +Q + L Y+E +YQ++
Sbjct: 112 DNLQILRDLSLLQIQMRDLEGYRE--TRYQLL 141
>gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo
sapiens]
Length = 515
Score = 45.4 bits (106), Expect = 4e-04
Identities = 64/278 (23%), Positives = 118/278 (42%), Gaps = 49/278 (17%)
Query: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT 704
LG Y+EA Q++ +K++E + + L +AK + ++D AL F
Sbjct: 238 LGMYREAEKQFKSALKQQE--------MVDTFLYLAKVYV-------SLDQPVTALNLFK 282
Query: 705 CALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGR 764
L K G+ T L +A ++ + + + K+VLK++
Sbjct: 283 QGLD---------KFPGEV-TLLCGIA--RIYEEMNNMSSAAEYYKEVLKQDNT------ 324
Query: 765 CYGRALKLMSTSNTWCD---LGINYYRQAQHLA-ETGSNMNDL------KELLEKSLHCL 814
+ A+ + +++ + D + + +YR+ + G N+L + + +L
Sbjct: 325 -HVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSF 383
Query: 815 KKAVRLDSNNHL---YWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLY 871
++A+ L N W LG VA GIG+ LA CF ++ + +A A+ NL VL
Sbjct: 384 ERALSLAENEEEAADVWYNLGHVAV--GIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 441
Query: 872 LTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVG 909
+ ++EQA + A SL P A I++ +G
Sbjct: 442 MRKGHVEQARALLQTASSLAPHMYEPHFNFATISDKIG 479
Score = 38.9 bits (89), Expect = 0.039
Identities = 19/71 (26%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 22 YKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81
Y+EA K K+ LKQ++ + ++++ L+QP A + +K+ + P ++ G+A
Sbjct: 241 YREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIA 299
Query: 82 NLYEKYNHINA 92
+YE+ N++++
Sbjct: 300 RIYEEMNNMSS 310
Score = 37.7 bits (86), Expect = 0.088
Identities = 29/135 (21%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 543 DMEMALAILTTVTQKASAGTAKWAW-LRRGLYYLKAGQHSQAVADLQAALRADPKDFNCW 601
D++ AL + T+ + W W ++ G Y + G + +A ++AL+ + +
Sbjct: 205 DVKTALDLAALSTEHSQY--KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTF 261
Query: 602 ESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKK 661
L + Y+S TAL F + + P + + +A I + + A Y+ ++K+
Sbjct: 262 LYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQ 321
Query: 662 KEDYVPALKGLGECH 676
+V A+ +G H
Sbjct: 322 DNTHVEAIACIGSNH 336
Score = 34.7 bits (78), Expect = 0.74
Identities = 48/200 (24%), Positives = 79/200 (39%), Gaps = 13/200 (6%)
Query: 366 YDSSEEAIRTLDQISDA-DNIPGLLVLK---SLAYRNKGSFDEAAKIMEDLLSSYPDLAE 421
Y S ++ + L+ D PG + L + Y + AA+ +++L E
Sbjct: 268 YVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVE 327
Query: 422 VHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTH 481
A HF A + ++R L+ + LGL ++ + D T LT
Sbjct: 328 AIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQY---DMT--LTS 382
Query: 482 FLKAARL---DTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLS 538
F +A L + V+ LGH + GD N A C+R A ++ AE+ L
Sbjct: 383 FERALSLAENEEEAADVWYNLGHVAVGI-GDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 441
Query: 539 VELEDMEMALAILTTVTQKA 558
+ +E A A+L T + A
Sbjct: 442 MRKGHVEQARALLQTASSLA 461
Score = 31.2 bits (69), Expect = 8.2
Identities = 39/165 (23%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 1017 DTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYER 1076
D +A+R Y RLL G Y+ Q F + L F Y + ++ER
Sbjct: 340 DQPEIALRFYRRLL-QMGIYNG--QLFNN-----------LGLCCFYAQQYDMTLTSFER 385
Query: 1077 ALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQ 1136
ALS+ E+E++ A + L G T++A + E+ L L +
Sbjct: 386 ALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKG 445
Query: 1137 DATLSKAALNELLKHIKHK-DSNYQRCLLTSAIYALQGRSVAVQK 1180
++A L H + ++ ++ I LQ VA QK
Sbjct: 446 HVEQARALLQTASSLAPHMYEPHFNFATISDKIGDLQRSYVAAQK 490
>gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo
sapiens]
Length = 475
Score = 45.4 bits (106), Expect = 4e-04
Identities = 64/278 (23%), Positives = 118/278 (42%), Gaps = 49/278 (17%)
Query: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT 704
LG Y+EA Q++ +K++E + + L +AK + ++D AL F
Sbjct: 198 LGMYREAEKQFKSALKQQE--------MVDTFLYLAKVYV-------SLDQPVTALNLFK 242
Query: 705 CALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGR 764
L K G+ T L +A ++ + + + K+VLK++
Sbjct: 243 QGLD---------KFPGEV-TLLCGIA--RIYEEMNNMSSAAEYYKEVLKQDNT------ 284
Query: 765 CYGRALKLMSTSNTWCD---LGINYYRQAQHLA-ETGSNMNDL------KELLEKSLHCL 814
+ A+ + +++ + D + + +YR+ + G N+L + + +L
Sbjct: 285 -HVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSF 343
Query: 815 KKAVRLDSNNHL---YWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLY 871
++A+ L N W LG VA GIG+ LA CF ++ + +A A+ NL VL
Sbjct: 344 ERALSLAENEEEAADVWYNLGHVAV--GIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 401
Query: 872 LTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVG 909
+ ++EQA + A SL P A I++ +G
Sbjct: 402 MRKGHVEQARALLQTASSLAPHMYEPHFNFATISDKIG 439
Score = 38.9 bits (89), Expect = 0.039
Identities = 19/71 (26%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 22 YKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81
Y+EA K K+ LKQ++ + ++++ L+QP A + +K+ + P ++ G+A
Sbjct: 201 YREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIA 259
Query: 82 NLYEKYNHINA 92
+YE+ N++++
Sbjct: 260 RIYEEMNNMSS 270
Score = 37.7 bits (86), Expect = 0.088
Identities = 29/135 (21%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 543 DMEMALAILTTVTQKASAGTAKWAW-LRRGLYYLKAGQHSQAVADLQAALRADPKDFNCW 601
D++ AL + T+ + W W ++ G Y + G + +A ++AL+ + +
Sbjct: 165 DVKTALDLAALSTEHSQY--KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTF 221
Query: 602 ESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKK 661
L + Y+S TAL F + + P + + +A I + + A Y+ ++K+
Sbjct: 222 LYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQ 281
Query: 662 KEDYVPALKGLGECH 676
+V A+ +G H
Sbjct: 282 DNTHVEAIACIGSNH 296
Score = 34.7 bits (78), Expect = 0.74
Identities = 48/200 (24%), Positives = 79/200 (39%), Gaps = 13/200 (6%)
Query: 366 YDSSEEAIRTLDQISDA-DNIPGLLVLK---SLAYRNKGSFDEAAKIMEDLLSSYPDLAE 421
Y S ++ + L+ D PG + L + Y + AA+ +++L E
Sbjct: 228 YVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVE 287
Query: 422 VHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTH 481
A HF A + ++R L+ + LGL ++ + D T LT
Sbjct: 288 AIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQY---DMT--LTS 342
Query: 482 FLKAARL---DTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLS 538
F +A L + V+ LGH + GD N A C+R A ++ AE+ L
Sbjct: 343 FERALSLAENEEEAADVWYNLGHVAVGI-GDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 401
Query: 539 VELEDMEMALAILTTVTQKA 558
+ +E A A+L T + A
Sbjct: 402 MRKGHVEQARALLQTASSLA 421
Score = 31.2 bits (69), Expect = 8.2
Identities = 39/165 (23%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 1017 DTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYER 1076
D +A+R Y RLL G Y+ Q F + L F Y + ++ER
Sbjct: 300 DQPEIALRFYRRLL-QMGIYNG--QLFNN-----------LGLCCFYAQQYDMTLTSFER 345
Query: 1077 ALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQ 1136
ALS+ E+E++ A + L G T++A + E+ L L +
Sbjct: 346 ALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKG 405
Query: 1137 DATLSKAALNELLKHIKHK-DSNYQRCLLTSAIYALQGRSVAVQK 1180
++A L H + ++ ++ I LQ VA QK
Sbjct: 406 HVEQARALLQTASSLAPHMYEPHFNFATISDKIGDLQRSYVAAQK 450
>gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo
sapiens]
Length = 505
Score = 45.4 bits (106), Expect = 4e-04
Identities = 64/278 (23%), Positives = 118/278 (42%), Gaps = 49/278 (17%)
Query: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT 704
LG Y+EA Q++ +K++E + + L +AK + ++D AL F
Sbjct: 228 LGMYREAEKQFKSALKQQE--------MVDTFLYLAKVYV-------SLDQPVTALNLFK 272
Query: 705 CALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGR 764
L K G+ T L +A ++ + + + K+VLK++
Sbjct: 273 QGLD---------KFPGEV-TLLCGIA--RIYEEMNNMSSAAEYYKEVLKQDNT------ 314
Query: 765 CYGRALKLMSTSNTWCD---LGINYYRQAQHLA-ETGSNMNDL------KELLEKSLHCL 814
+ A+ + +++ + D + + +YR+ + G N+L + + +L
Sbjct: 315 -HVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSF 373
Query: 815 KKAVRLDSNNHL---YWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLY 871
++A+ L N W LG VA GIG+ LA CF ++ + +A A+ NL VL
Sbjct: 374 ERALSLAENEEEAADVWYNLGHVAV--GIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 431
Query: 872 LTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVG 909
+ ++EQA + A SL P A I++ +G
Sbjct: 432 MRKGHVEQARALLQTASSLAPHMYEPHFNFATISDKIG 469
Score = 38.9 bits (89), Expect = 0.039
Identities = 19/71 (26%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 22 YKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81
Y+EA K K+ LKQ++ + ++++ L+QP A + +K+ + P ++ G+A
Sbjct: 231 YREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIA 289
Query: 82 NLYEKYNHINA 92
+YE+ N++++
Sbjct: 290 RIYEEMNNMSS 300
Score = 37.7 bits (86), Expect = 0.088
Identities = 29/135 (21%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 543 DMEMALAILTTVTQKASAGTAKWAW-LRRGLYYLKAGQHSQAVADLQAALRADPKDFNCW 601
D++ AL + T+ + W W ++ G Y + G + +A ++AL+ + +
Sbjct: 195 DVKTALDLAALSTEHSQY--KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTF 251
Query: 602 ESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKK 661
L + Y+S TAL F + + P + + +A I + + A Y+ ++K+
Sbjct: 252 LYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQ 311
Query: 662 KEDYVPALKGLGECH 676
+V A+ +G H
Sbjct: 312 DNTHVEAIACIGSNH 326
Score = 34.7 bits (78), Expect = 0.74
Identities = 48/200 (24%), Positives = 79/200 (39%), Gaps = 13/200 (6%)
Query: 366 YDSSEEAIRTLDQISDA-DNIPGLLVLK---SLAYRNKGSFDEAAKIMEDLLSSYPDLAE 421
Y S ++ + L+ D PG + L + Y + AA+ +++L E
Sbjct: 258 YVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVE 317
Query: 422 VHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTH 481
A HF A + ++R L+ + LGL ++ + D T LT
Sbjct: 318 AIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQY---DMT--LTS 372
Query: 482 FLKAARL---DTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLS 538
F +A L + V+ LGH + GD N A C+R A ++ AE+ L
Sbjct: 373 FERALSLAENEEEAADVWYNLGHVAVGI-GDTNLAHQCFRLALVNNNNHAEAYNNLAVLE 431
Query: 539 VELEDMEMALAILTTVTQKA 558
+ +E A A+L T + A
Sbjct: 432 MRKGHVEQARALLQTASSLA 451
Score = 31.2 bits (69), Expect = 8.2
Identities = 39/165 (23%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 1017 DTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYER 1076
D +A+R Y RLL G Y+ Q F + L F Y + ++ER
Sbjct: 330 DQPEIALRFYRRLL-QMGIYNG--QLFNN-----------LGLCCFYAQQYDMTLTSFER 375
Query: 1077 ALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQ 1136
ALS+ E+E++ A + L G T++A + E+ L L +
Sbjct: 376 ALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKG 435
Query: 1137 DATLSKAALNELLKHIKHK-DSNYQRCLLTSAIYALQGRSVAVQK 1180
++A L H + ++ ++ I LQ VA QK
Sbjct: 436 HVEQARALLQTASSLAPHMYEPHFNFATISDKIGDLQRSYVAAQK 480
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 45.4 bits (106), Expect = 4e-04
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 26/183 (14%)
Query: 309 WYHLAEAQVKMHRPKEAVLSCSQALKI--VDNLGASGNSLY-QRNLCLHLKAEALIKLSD 365
WY+LA +++ P EA+ + ++AL++ L +++ Q + + L+ EA +L
Sbjct: 600 WYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLS 659
Query: 366 YDSSEE---------AIRTLDQISDAD-------------NIPGLLVLKSLAYRNKGSFD 403
Y + E + +D D + + L +L Y
Sbjct: 660 YINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNLALLYSQTAKEL 719
Query: 404 EAAKIMEDLLSSYPDLAEVHALEA-LIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGL 462
+A I+E+LL YPD + L+ ++ KKD L A+KCF+R LE D + + L +
Sbjct: 720 KALPILEELLRYYPDHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSNVQGKHNLCV 779
Query: 463 TYW 465
Y+
Sbjct: 780 VYF 782
Score = 43.1 bits (100), Expect = 0.002
Identities = 83/433 (19%), Positives = 170/433 (39%), Gaps = 61/433 (14%)
Query: 18 RNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAW 77
RN +++ + LK KNN W +G A + ++A + +A ++PD + A
Sbjct: 424 RNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAH 483
Query: 78 QGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVAR 137
+ Y+ N ++ + + L+ + + +K+ HL V
Sbjct: 484 MNVGRTYKNLNRTKEAEESYMMAKSLMP--QIIPGKKYAARIAP---------NHLNVYI 532
Query: 138 TWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQLLFTAFENALGLSDKIP 197
LI+ + + EE QL+R+ + +Q + E L ++ +
Sbjct: 533 NLANLIRANESR---LEEADQLYRQAISM--------RPDFKQAYISRGELLLKMNKPLK 581
Query: 198 SEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPLEVLCLHLIESGNLTDEG 257
+++ ++++L + +A L Y L ++ + L E +E
Sbjct: 582 AKEA------YLKAL-ELDRNNADL--------------WYNLAIVHIELKEP----NEA 616
Query: 258 QQYCCRLVEMDSKSGPGLIGLGIKALQD---KKYEDAVRNLTEGLKESPVCTSGWYHLAE 314
+ R +E++ K L I + K +A + L + E P+ +G+++L
Sbjct: 617 LKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLGM 676
Query: 315 AQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIR 374
+ + EA + +A+K+ + ++ L+ NL L L ++ +L EE +R
Sbjct: 677 LAMDDKKDNEAEIWMKKAIKLQADFRSA---LF--NLAL-LYSQTAKELKALPILEELLR 730
Query: 375 TLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKK 434
D+I GL++ + K A K E +L P + +++F +K
Sbjct: 731 YYP-----DHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSNVQGKHNLCVVYFEEK 785
Query: 435 DYLQAEKCFQRAL 447
D L+AE+C L
Sbjct: 786 DLLKAERCLLETL 798
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 564 KWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTK 623
K A++ RG LK + +A AL D + + W +L ++ ALK+F +
Sbjct: 563 KQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNR 622
Query: 624 ASELNPESIYSVFKVAAIQQILGKYK-EAVAQYQMIIKKKEDYVPALKGLGECHLMMAKA 682
A ELNP+ ++F A + Q G+ K A+ +++ E+ + A + +
Sbjct: 623 ALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDA-----NGYFNLGML 677
Query: 683 ALVDYLDGKAVDYIEKALE 701
A+ D D +A +++KA++
Sbjct: 678 AMDDKKDNEAEIWMKKAIK 696
Score = 41.6 bits (96), Expect = 0.006
Identities = 24/118 (20%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
Query: 846 AQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIA 905
A+ ++K+++ ++ NA W NL ++++ + +A + F A L+P + + A++
Sbjct: 582 AKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVM 641
Query: 906 EAVGSYDTMDLFRH--TTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMNA 961
+ G R + +N A GY + DK + E E++ +++ A
Sbjct: 642 QESGEVKLRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQA 699
Score = 38.9 bits (89), Expect = 0.039
Identities = 21/82 (25%), Positives = 37/82 (45%)
Query: 589 AALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKY 648
+AL+ + + W ++G A + + ALK F +A+ + P+ I + V + L +
Sbjct: 437 SALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRT 496
Query: 649 KEAVAQYQMIIKKKEDYVPALK 670
KEA Y M +P K
Sbjct: 497 KEAEESYMMAKSLMPQIIPGKK 518
Score = 35.0 bits (79), Expect = 0.57
Identities = 23/99 (23%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Query: 391 LKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKD 450
L +L N+ +EA ++ +S PD + + + L+A++ + +ALE D
Sbjct: 534 LANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELD 593
Query: 451 TEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLD 489
A+ Y L + + + K+ +AL +F +A L+
Sbjct: 594 RNNADLWYNLAIVHIEL-----KEPNEALKNFNRALELN 627
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 44.3 bits (103), Expect = 0.001
Identities = 22/87 (25%), Positives = 44/87 (50%)
Query: 596 KDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQY 655
++ ++ G AY ++ Y A +TKA ++ P++ AA +LG+++EA+
Sbjct: 26 REAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDA 85
Query: 656 QMIIKKKEDYVPALKGLGECHLMMAKA 682
Q ++ + +V G+CHL + A
Sbjct: 86 QQSVRLDDSFVRGHLREGKCHLSLGNA 112
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 44.3 bits (103), Expect = 0.001
Identities = 25/106 (23%), Positives = 47/106 (44%)
Query: 571 GLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPE 630
G YY QH +A Q AL+ +P+ W +G Y+ + A++++ A E+N
Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397
Query: 631 SIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECH 676
+ + + +IL + Y+ + + + L LGEC+
Sbjct: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECY 443
Score = 37.0 bits (84), Expect = 0.15
Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 12/158 (7%)
Query: 16 AIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLL 75
++R++ K AL + + LK AW +G E++ A AY+ A E+
Sbjct: 342 SLRSQHEKAAL-YFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYR 400
Query: 76 AWQGLANLYE--------KYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYY 127
AW GL YE Y + A P + L+ L E +K KK Y+
Sbjct: 401 AWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK---CYW 457
Query: 128 QEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQ 165
+ +V + + EQ E+E+ Q + K Q
Sbjct: 458 RAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Score = 35.0 bits (79), Expect = 0.57
Identities = 36/171 (21%), Positives = 66/171 (38%), Gaps = 15/171 (8%)
Query: 566 AWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKAS 625
AW G Y++ S A+ + A+ + +D+ W LG+ Y L + +A
Sbjct: 367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAH 426
Query: 626 ELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMM-----A 680
+L P + + + L + EA Y + AL L + H + A
Sbjct: 427 QLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQA 486
Query: 681 KAALVDYLD-----GKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTC 726
+ Y+ G+ V+++E+ + A ++ A KL +A TC
Sbjct: 487 AQCYIKYIQDIYSCGEIVEHLEE-----STAFRYLAQYYFKCKLWDEASTC 532
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 48/288 (16%)
Query: 395 AYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVA 454
AY+ K FD A K + P +A ++F K DY + + ++A+E E
Sbjct: 235 AYKKK-DFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENR 293
Query: 455 EYHYQLGLTYWFMGEET-RKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRA 513
E + Q+ Y +G +++K K HF + + H DV+ +A
Sbjct: 294 EDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAE-----------HRTPDVLKKCQQA 342
Query: 514 RGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLY 573
++ L A ++ + LE+ +G
Sbjct: 343 EKILKEQERL---------AYINPDLALEEKN------------------------KGNE 369
Query: 574 YLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIY 633
+ G + QA+ A++ +PKD + + Y + ALK + +L P I
Sbjct: 370 CFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIK 429
Query: 634 SVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAK 681
+ AA + + Y +A+ YQ + A G C MMA+
Sbjct: 430 GYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRC--MMAQ 475
Score = 38.1 bits (87), Expect = 0.067
Identities = 25/112 (22%), Positives = 48/112 (42%)
Query: 570 RGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNP 629
+G L G A+ A++ DP + + + AY +G Y A + K +L P
Sbjct: 10 KGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKP 69
Query: 630 ESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAK 681
+ + AA + L +++EA Y+ +K + + +GL +A+
Sbjct: 70 DWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAE 121
>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 42.7 bits (99), Expect = 0.003
Identities = 73/314 (23%), Positives = 116/314 (36%), Gaps = 39/314 (12%)
Query: 364 SDYDSSEEAIRTLDQIS--DADNIPGLLV---LKSLAYRNKGSFDEAAKIMEDLLSSYPD 418
SD D ++ L++++ DA+ P L L S Y F+E E+ L +P
Sbjct: 283 SDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEE-----ENPLRDHPQ 337
Query: 419 LAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKA 478
E E L + D A F+ A+++D + E LG T +E
Sbjct: 338 PFE----EGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALR 393
Query: 479 LTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDL- 537
LK M + + + R Y A+ T AE GA L
Sbjct: 394 RCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLG 453
Query: 538 ------------SVELEDMEMALAIL----TTVTQKASAGTAKWAWLRRGLYYLKAGQHS 581
S+ LE E+ LA + T++ G G+ + +G++
Sbjct: 454 PSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGL--------GVLFNLSGEYD 505
Query: 582 QAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAI 641
+AV AAL P D+ W LG + A+ ++ +A EL P I S + +
Sbjct: 506 KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGIS 565
Query: 642 QQILGKYKEAVAQY 655
LG ++EAV +
Sbjct: 566 CINLGAHREAVEHF 579
Score = 36.2 bits (82), Expect = 0.26
Identities = 18/52 (34%), Positives = 28/52 (53%)
Query: 30 KTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81
+ ++Q+ + AW ++G AE EQ A SA ++ EL+PD A LA
Sbjct: 359 EAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALA 410
Score = 35.4 bits (80), Expect = 0.44
Identities = 17/51 (33%), Positives = 27/51 (52%)
Query: 21 EYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEP 71
EY +A+ L N+Y W +G A Q ++A +AY++A EL+P
Sbjct: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 553
Score = 35.0 bits (79), Expect = 0.57
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 5/107 (4%)
Query: 794 AETGSNMNDLKELLEKSLHCLKK-----AVRLDSNNHLYWNALGVVACYSGIGNYALAQH 848
A G + L LL SL K AVRLD + G+ ++ G Y A
Sbjct: 450 AGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVD 509
Query: 849 CFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYL 895
CF ++ + + W LG E+A A++ A L P Y+
Sbjct: 510 CFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYI 556
Score = 32.7 bits (73), Expect = 2.8
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 589 AALRADPK----DFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQI 644
AA+R DP D C LG + G Y A+ FT A + P K+ A
Sbjct: 477 AAVRLDPTSIDPDVQC--GLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
Query: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLG 673
+ +EAVA Y+ ++ + Y+ + LG
Sbjct: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLG 563
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,261,476
Number of Sequences: 37866
Number of extensions: 2208951
Number of successful extensions: 7103
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 6205
Number of HSP's gapped (non-prelim): 802
length of query: 1564
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1448
effective length of database: 13,855,062
effective search space: 20062129776
effective search space used: 20062129776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.